WB:WBGene00000001 aap-1 Enables protein kinase binding activity. Involved in dauer larval development; determination of adult lifespan; and insulin receptor signaling pathway. Part of phosphatidylinositol 3-kinase complex. Expressed in anchor cell; intestine; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; SHORT syndrome; arthritis (multiple); and carcinoma (multiple). Is an ortholog of human PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2). WB:WBGene00000002 aat-1 Contributes to L-amino acid transmembrane transporter activity. Involved in amino acid transmembrane transport. Located in plasma membrane. Part of amino acid transport complex. Expressed in egg-laying apparatus; head motor neurons; and tail. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); glioblastoma; and lysinuric protein intolerance. Is an ortholog of human SLC7A8 (solute carrier family 7 member 8). WB:WBGene00000003 aat-2 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); esophagitis; and glioblastoma. Is an ortholog of human SLC7A5 (solute carrier family 7 member 5) and SLC7A8 (solute carrier family 7 member 8). WB:WBGene00000004 aat-3 Contributes to L-amino acid transmembrane transporter activity. Involved in amino acid transmembrane transport. Located in plasma membrane. Part of amino acid transport complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); esophagitis; and glioblastoma. Is an ortholog of human SLC7A5 (solute carrier family 7 member 5) and SLC7A8 (solute carrier family 7 member 8). WB:WBGene00000005 aat-4 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. WB:WBGene00000006 aat-5 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. WB:WBGene00000007 aat-6 Enables PDZ domain binding activity. Predicted to be involved in amino acid transmembrane transport. Located in apical plasma membrane. WB:WBGene00000008 aat-7 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. WB:WBGene00000009 aat-8 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. WB:WBGene00000010 aat-9 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Located in cell surface. Expressed in body wall musculature and neurons. WB:WBGene00000011 abc-1 Acts upstream of or within mitotic sister chromatid separation. WB:WBGene00000012 abf-1 Predicted to be involved in defense response to other organism. Predicted to be located in extracellular region. Expressed in body wall musculature; intestine; neurons; and pharynx. WB:WBGene00000013 abf-2 Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Predicted to be located in extracellular region. Expressed in excretory cell; marginal cell; and pharyngeal neurons. WB:WBGene00000014 abf-3 Involved in defense response to Gram-negative bacterium and innate immune response. Expressed in intestine and rectal gland cell. WB:WBGene00000015 abf-4 Is affected by several genes including daf-12; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Cadmium Chloride; bortezomib; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00000016 abf-5 Enriched in FLP based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00000017 abf-6 Enriched in posterior arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including rotenone; multi-walled carbon nanotube; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00000018 abl-1 Predicted to enable non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including defense response to other organism; negative regulation of DNA damage response, signal transduction by p53 class mediator; and negative regulation of engulfment of apoptotic cell. Predicted to be located in cytoplasm. Expressed in Q cell; germ cell; neurons; pharynx; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); leukemia (multiple); and lung non-small cell carcinoma. Is an ortholog of human ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) and ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase). WB:WBGene00000019 abt-1 Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human ABCA5 (ATP binding cassette subfamily A member 5). WB:WBGene00000020 abt-2 Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 9; autosomal recessive congenital ichthyosis (multiple); hypolipoproteinemia (multiple); and retinal degeneration (multiple). Is an ortholog of human ABCA12 (ATP binding cassette subfamily A member 12). WB:WBGene00000021 abt-3 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and npr-1 based on RNA-seq; tiling array; and microarray studies. Is affected by seven chemicals including Tunicamycin; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00000022 abt-4 Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in intracellular membrane-bounded organelle. Expressed in head and tail. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Is an ortholog of human ABCA3 (ATP binding cassette subfamily A member 3). WB:WBGene00000023 abt-5 Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in intracellular membrane-bounded organelle. Expressed in head. Is an ortholog of human ABCA10 (ATP binding cassette subfamily A member 10). WB:WBGene00000024 abu-1 Involved in endoplasmic reticulum unfolded protein response. Located in endoplasmic reticulum membrane. Expressed in pharynx. WB:WBGene00000025 abu-2 Involved in endoplasmic reticulum unfolded protein response. WB:WBGene00000026 abu-3 Is affected by several genes including lin-4; lin-14; and sir-2.1 based on microarray and RNA-seq studies. Is affected by resveratrol; Chlorpyrifos; and Sirolimus based on microarray studies. WB:WBGene00000027 abu-4 Involved in endoplasmic reticulum unfolded protein response. WB:WBGene00000028 abu-5 Involved in endoplasmic reticulum unfolded protein response. Expressed in pharyngeal muscle cell. WB:WBGene00000029 abu-6 Involved in pharynx development. Expressed in pharyngeal muscle cell. WB:WBGene00000030 abu-7 Involved in pharynx development. WB:WBGene00000031 abu-8 Involved in pharynx development. WB:WBGene00000032 abu-9 Involved in endoplasmic reticulum unfolded protein response. WB:WBGene00000033 abu-10 Involved in endoplasmic reticulum unfolded protein response. WB:WBGene00000034 abu-11 Involved in endoplasmic reticulum unfolded protein response. WB:WBGene00000035 ace-1 Enables acetylcholinesterase activity and identical protein binding activity. Involved in acetylcholine catabolic process and regulation of locomotion. Located in extracellular space. Expressed in CEP; M cell; OLL; body wall musculature; and non-striated muscle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); and autoimmune disease (multiple). Is an ortholog of human ACHE (acetylcholinesterase (Cartwright blood group)) and BCHE (butyrylcholinesterase). WB:WBGene00000036 ace-2 Enables acetylcholinesterase activity and protein homodimerization activity. Involved in acetylcholine catabolic process; cholinergic synaptic transmission; and regulation of locomotion. Predicted to be located in extracellular space and plasma membrane. Expressed in several structures, including command interneuron; neurons; pm5; somatic nervous system; and tail hypodermis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Huntington's disease; artery disease (multiple); and diabetes mellitus (multiple). Is an ortholog of human BCHE (butyrylcholinesterase). WB:WBGene00000037 ace-3 Enables acetylcholinesterase activity and protein homodimerization activity. Involved in several processes, including acetylcholine catabolic process; hatching; and regulation of backward locomotion. Predicted to be located in extracellular space and plasma membrane. Expressed in body wall musculature; neurons; pharyngeal muscle cell; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); and autoimmune disease (multiple). Is an ortholog of human ACHE (acetylcholinesterase (Cartwright blood group)) and BCHE (butyrylcholinesterase). WB:WBGene00000038 ace-4 Predicted to enable cholinesterase activity. Predicted to be involved in neurotransmitter catabolic process. Predicted to be located in extracellular space and plasma membrane. Expressed in body wall musculature; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); and autoimmune disease (multiple). Is an ortholog of human ACHE (acetylcholinesterase (Cartwright blood group)) and BCHE (butyrylcholinesterase). WB:WBGene00000039 acn-1 Predicted to enable metallopeptidase activity. Involved in ecdysis, collagen and cuticulin-based cuticle and nematode male tail tip morphogenesis. Acts upstream of or within with a negative effect on plasma membrane fusion. Predicted to be located in plasma membrane. Expressed in excretory gland cell; hypodermis; vulva; and in male. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Is an ortholog of human ACE2 (angiotensin converting enzyme 2). WB:WBGene00000040 aco-1 Enables aconitate hydratase activity. Involved in tricarboxylic acid metabolic process. Located in cytosol. Expressed in seam cell. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human ACO1 (aconitase 1). WB:WBGene00000041 aco-2 Predicted to enable 4 iron, 4 sulfur cluster binding activity and aconitate hydratase activity. Predicted to be involved in tricarboxylic acid cycle. Located in mitochondrion. Expressed widely. Human ortholog(s) of this gene implicated in infantile cerebellar-retinal degeneration and optic atrophy 9. Is an ortholog of human ACO2 (aconitase 2). WB:WBGene00000042 acr-2 Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in several processes, including calcium ion import across plasma membrane; neuromuscular synaptic transmission; and positive regulation of translation. Located in neuron projection. Expressed in AVE; DVB; cholinergic neurons; somatic nervous system; and vulval muscle. Human ortholog(s) of this gene implicated in lung disease (multiple); nicotine dependence; and stomach cancer. Is an ortholog of human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit) and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). WB:WBGene00000043 acr-3 Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in calcium ion import across plasma membrane. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in several diseases, including congenital myasthenic syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit) and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). WB:WBGene00000044 acr-5 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in cellular response to nicotine. Predicted to be located in neuron projection and synapse. Expressed in nerve ring; neurons; and tail. WB:WBGene00000045 acr-6 Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in lung disease (multiple); nicotine dependence; and stomach cancer. Is an ortholog of human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit) and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). WB:WBGene00000046 acr-7 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). WB:WBGene00000047 acr-8 Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in body wall musculature; enteric muscle; nerve ring; neurons; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including congenital myasthenic syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit); and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). WB:WBGene00000048 acr-9 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). WB:WBGene00000049 acr-10 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). WB:WBGene00000050 acr-11 Predicted to enable acetylcholine receptor activity; excitatory extracellular ligand-gated monoatomic ion channel activity; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in chemical synaptic transmission. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). WB:WBGene00000051 acr-12 Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in calcium ion import across plasma membrane and regulation of muscle contraction. Located in synapse. Expressed in neurons. Human ortholog(s) of this gene implicated in several diseases, including congenital myasthenic syndrome (multiple); lung disease (multiple); and nicotine dependence. Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit); and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). WB:WBGene00000053 acr-14 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). WB:WBGene00000054 acr-15 Predicted to enable acetylcholine receptor activity; excitatory extracellular ligand-gated monoatomic ion channel activity; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in cellular response to nicotine and chemical synaptic transmission. Predicted to be located in neuron projection and synapse. Expressed in body wall musculature and neurons. Used to study nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). WB:WBGene00000055 acr-16 Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in monoatomic ion transmembrane transport. Located in cell projection. Expressed in body wall musculature; linker cell; muscle cell; and neurons. Used to study nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). WB:WBGene00000056 acr-17 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00000057 acr-18 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in neurons and ray. WB:WBGene00000058 acr-19 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). WB:WBGene00000059 acr-20 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00000060 acr-21 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in cholinergic neurons and ventral cord neurons. Human ortholog(s) of this gene implicated in lung small cell carcinoma. Is an ortholog of human CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit). WB:WBGene00000061 lgc-11 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00000062 acr-23 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in body wall musculature; interneuron; and touch receptor neurons. WB:WBGene00000063 act-1 Predicted to be a structural constituent of cytoskeleton. Involved in cortical actin cytoskeleton organization; embryo development; and mitotic cytokinesis. Located in striated muscle thin filament. Expressed in body wall musculature and gonad. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Is an ortholog of human ACTB (actin beta). WB:WBGene00000064 act-2 Predicted to enable ATP binding activity. Involved in several processes, including cortical actin cytoskeleton organization; cytoskeleton-dependent cytokinesis; and embryo development. Located in actin filament and cell cortex. Expressed in body wall musculature; gonad; hypodermis; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Is an ortholog of human ACTB (actin beta). WB:WBGene00000065 act-3 Expressed in gonad and head. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Human ACTB Contributes to nucleosomal DNA binding activity. Human ACTB enables several functions, including Tat protein binding activity; enzyme binding activity; and kinesin binding activity. A structural constituent of postsynaptic actin cytoskeleton. Is predicted to encode a protein with the following domains: ATPase, nucleotide binding domain; Actin; Actin family; and Phosphorylation site. Is an ortholog of human ACTB (actin beta). WB:WBGene00000066 act-4 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in actin cytoskeleton organization and mitotic cytokinesis. Located in striated muscle thin filament. Expressed in body wall musculature; gonad; spermatheca; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Is an ortholog of human ACTB (actin beta). WB:WBGene00000067 act-5 Involved in several processes, including larval feeding behavior; microvillus assembly; and positive regulation of eating behavior. Located in microvillar actin bundle and terminal web. Expressed in excretory cell; gonad; intestine; pharyngeal-intestinal valve; and rectal gland cell. WB:WBGene00000068 acy-1 Predicted to enable adenylate cyclase activity. Involved in several processes, including locomotory exploration behavior; memory; and regulation of defecation. Predicted to be located in plasma membrane. Expressed in body wall musculature; ganglia; neurons; ventral nerve cord; and vulval muscle. Human ortholog(s) of this gene implicated in mood disorder. Is an ortholog of human ADCY9 (adenylate cyclase 9). WB:WBGene00000069 acy-2 Predicted to enable adenylate cyclase activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway and nematode larval development. Predicted to be located in plasma membrane. Expressed in CANL; CANR; head ganglion; and ventral cord neurons. Is an ortholog of human ADCY2 (adenylate cyclase 2) and ADCY7 (adenylate cyclase 7). WB:WBGene00000070 acy-3 Predicted to enable calcium- and calmodulin-responsive adenylate cyclase activity. Involved in negative regulation of protein kinase C signaling and regulation of establishment of cell polarity. Predicted to be located in plasma membrane. WB:WBGene00000071 acy-4 Predicted to enable adenylate cyclase activity. Involved in oocyte growth. Acts upstream of or within with a positive effect on oocyte maturation. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 44 and lethal congenital contracture syndrome. Is an ortholog of human ADCY6 (adenylate cyclase 6). WB:WBGene00000072 add-1 Predicted to enable actin filament binding activity. Involved in actin filament bundle organization; memory; and receptor localization to synapse. Located in postsynaptic density. Expressed in GLR; coelomocyte; and neurons. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); and familial combined hyperlipidemia. Is an ortholog of human ADD1 (adducin 1); ADD2 (adducin 2); and ADD3 (adducin 3). WB:WBGene00000073 add-2 Predicted to enable actin filament binding activity. Predicted to be located in cytoskeleton; plasma membrane; and postsynaptic density. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); and familial combined hyperlipidemia. Is an ortholog of human ADD1 (adducin 1); ADD2 (adducin 2); and ADD3 (adducin 3). WB:WBGene00000074 adm-2 Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Predicted to be located in endosome membrane; lysosomal membrane; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); endocrine gland cancer (multiple); and lung disease (multiple). Is an ortholog of human ADAM19 (ADAM metallopeptidase domain 19) and ADAM33 (ADAM metallopeptidase domain 33). WB:WBGene00000075 adm-4 Predicted to enable metalloendopeptidase activity. Involved in Notch signaling pathway and cell fate specification. Predicted to be located in plasma membrane. Expressed in gonad; hypodermis; tail; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease; inflammatory bowel disease; renal fibrosis; and type 2 diabetes mellitus. Is an ortholog of human ADAM17 (ADAM metallopeptidase domain 17). WB:WBGene00000076 adn-1 No description available WB:WBGene00000077 adn-2 No description available WB:WBGene00000078 adp-1 Acts upstream of or within negative adaptation of signaling pathway. WB:WBGene00000079 adr-1 Enables mRNA binding activity. Involved in several processes, including adenosine to inosine editing; determination of adult lifespan; and regulation of vulval development. Located in cytosolic ribosome and nucleus. Expressed in body wall musculature; intestine; nervous system; and vulva. WB:WBGene00000080 adr-2 Enables double-stranded RNA adenosine deaminase activity. Involved in adenosine to inosine editing; determination of adult lifespan; and positive regulation of chemotaxis. Located in cytoplasm and nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including Aicardi-Goutieres syndrome; Human papillomavirus infectious disease; and dyschromatosis symmetrica hereditaria. Is an ortholog of human ADARB1 (adenosine deaminase RNA specific B1). WB:WBGene00000081 ads-1 Predicted to enable FAD binding activity and alkylglycerone-phosphate synthase activity. Predicted to be involved in ether lipid biosynthetic process. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata type 3. Is an ortholog of human AGPS (alkylglycerone phosphate synthase). WB:WBGene00000082 adt-1 Predicted to enable metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization. Predicted to be located in extracellular matrix. Expressed in several structures, including amphid neurons; body wall musculature; pharyngeal muscle cell; ventral nerve cord; and vulva. WB:WBGene00000083 adt-2 Predicted to enable metalloendopeptidase activity. Involved in several processes, including collagen fibril organization; determination of adult lifespan; and regulation of cell size. Predicted to be located in extracellular matrix. Expressed in socket cell and vulva. WB:WBGene00000084 aex-1 Involved in several processes, including lipid transport involved in lipid storage; positive regulation of transport; and reproductive behavior. Predicted to be located in exocytic vesicle. Expressed in amphid neurons; body wall musculature; and intestine. WB:WBGene00000085 aex-2 Predicted to enable neuropeptide receptor activity. Involved in lipid transport involved in lipid storage; neuropeptide signaling pathway; and positive regulation of transport. Predicted to be located in cilium and plasma membrane. Expressed in alimentary muscle; head mesodermal cell; and somatic nervous system. WB:WBGene00000086 aex-3 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in several processes, including egg-laying behavior; mating; and positive regulation of transport. Predicted to be located in cytosol. Expressed in neurons. Used to study alcohol use disorder. Is an ortholog of human MADD (MAP kinase activating death domain). WB:WBGene00000088 aex-5 Enables serine-type endopeptidase activity. Involved in several processes, including neuropeptide processing; positive regulation of synaptic assembly at neuromuscular junction; and positive regulation of transport. Located in extracellular space. WB:WBGene00000089 aex-6 Predicted to enable GTP binding activity and GTPase activity. Involved in exocytosis; positive regulation of defecation; and positive regulation of protein catabolic process. Located in synaptic vesicle. Expressed in ALML; ALMR; BDUL; BDUR; and neurons. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Is an ortholog of human RAB27A (RAB27A, member RAS oncogene family). WB:WBGene00000090 age-1 Predicted to enable 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in several processes, including dauer entry; determination of adult lifespan; and regulation of synaptic assembly at neuromuscular junction. Located in cytoplasm and non-motile cilium. Part of phosphatidylinositol 3-kinase complex. Expressed in amphid neurons; anchor cell; hypodermis; and pharyngeal-intestinal valve. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of human PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta); PIK3CD (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta); and PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma). WB:WBGene00000091 age-2 No description available WB:WBGene00000092 ags-3 Enables G-protein alpha-subunit binding activity. Involved in regulation of feeding behavior. Located in membrane. Expressed in several structures, including hermaphrodite gonad; intestine; muscle cell; neurons; and tail. Human ortholog(s) of this gene implicated in sensorineural hearing loss. Is an ortholog of human GPSM1 (G protein signaling modulator 1) and GPSM2 (G protein signaling modulator 2). WB:WBGene00000093 agt-1 Enables damaged DNA binding activity and transferase activity, transferring alkyl or aryl (other than methyl) groups. Involved in DNA dealkylation involved in DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endocrine gland cancer (multiple); and high grade glioma (multiple). Is an ortholog of human MGMT (O-6-methylguanine-DNA methyltransferase). WB:WBGene00000094 agt-2 Enriched in OLL; PVD; germ line; and neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00000095 aha-1 Enables DNA binding activity; DNA-binding transcription factor activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Contributes to sequence-specific DNA binding activity. Involved in several processes, including cell differentiation; determination of adult lifespan; and social behavior. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in hypodermis; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in renal cell carcinoma and type 2 diabetes mellitus. Is an ortholog of human ARNT (aryl hydrocarbon receptor nuclear translocator) and ARNT2 (aryl hydrocarbon receptor nuclear translocator 2). WB:WBGene00000096 ahr-1 Enables DNA binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of locomotion and response to xenobiotic stimulus. Predicted to be located in nucleus. Predicted to be part of nuclear aryl hydrocarbon receptor complex. Expressed in ALML; ALMR; RMEL; RMER; and neurons. Human ortholog(s) of this gene implicated in pancreatic cancer and retinitis pigmentosa 85. Is an ortholog of human AHR (aryl hydrocarbon receptor). WB:WBGene00000097 aip-1 Predicted to enable zinc ion binding activity. Involved in cellular response to misfolded protein and response to arsenic-containing substance. Located in cytoplasm and nucleus. Expressed in body wall musculature; excretory cell; pharynx; and somatic gonad. Is an ortholog of human ZFAND2A (zinc finger AN1-type containing 2A) and ZFAND2B (zinc finger AN1-type containing 2B). WB:WBGene00000098 air-1 Enables protein serine/threonine kinase activity. Involved in mitotic spindle assembly and positive regulation of protein localization to centrosome. Located in condensed nuclear chromosome and spindle. Expressed in anterior distal tip cell; germ line; and posterior distal tip cell. WB:WBGene00000099 air-2 Enables ATPase binding activity; kinesin binding activity; and protein serine/threonine kinase activity. Involved in several processes, including chromosome condensation; regulation of actomyosin contractile ring contraction; and spindle midzone assembly. Located in condensed nuclear chromosome and spindle midzone. Expressed in oocyte and sperm. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); invasive ductal carcinoma; and prostate carcinoma in situ. Is an ortholog of human AURKB (aurora kinase B). WB:WBGene00000100 ajm-1 Predicted to enable cytoskeletal protein binding activity. Involved in cell-cell junction organization and embryo development. Located in apicolateral plasma membrane; cell-cell junction; and plasma membrane bounded cell projection. Expressed in several structures, including arcade cell and epithelial cell. Is an ortholog of human AJM1 (apical junction component 1 homolog). WB:WBGene00000101 aka-1 Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in endosomal transport. Predicted to be located in early endosome membrane. Is an ortholog of human ZFYVE9 (zinc finger FYVE-type containing 9). WB:WBGene00000102 akt-1 Enables calmodulin binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and protein serine/threonine kinase activity. Involved in several processes, including determination of adult lifespan; regulation of synaptic assembly at neuromuscular junction; and signal transduction. Located in axon; cytoplasmic side of plasma membrane; and somatodendritic compartment. Expressed in several structures, including excretory canal; neurons; pharynx; rectal gland cell; and ventral nerve cord. Used to study cancer. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); coronary artery disease (multiple); and glucose metabolism disease (multiple). Is an ortholog of human AKT1 (AKT serine/threonine kinase 1); AKT2 (AKT serine/threonine kinase 2); and AKT3 (AKT serine/threonine kinase 3). WB:WBGene00000103 akt-2 Enables phosphatidylinositol-3,4,5-trisphosphate binding activity and protein serine/threonine kinase activity. Involved in determination of adult lifespan; insulin receptor signaling pathway; and regulation of synaptic assembly at neuromuscular junction. Expressed in several structures, including excretory canal; neurons; pharynx; rectum; and vulva. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); coronary artery disease (multiple); and glucose metabolism disease (multiple). Is an ortholog of human AKT1 (AKT serine/threonine kinase 1); AKT2 (AKT serine/threonine kinase 2); and AKT3 (AKT serine/threonine kinase 3). WB:WBGene00000104 ale-1 No description available WB:WBGene00000105 alg-1 Enables RNA binding activity and RNA endonuclease activity. Involved in several processes, including regulation of development, heterochronic; regulatory ncRNA-mediated gene silencing; and vulval development. Located in P-body. Part of RISC complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; gonad; somatic cell; and tail. Is an ortholog of human AGO2 (argonaute RISC catalytic component 2). WB:WBGene00000106 alg-2 Enables RNA binding activity and RNA endonuclease activity. Involved in embryo development; nematode larval development; and regulatory ncRNA-mediated gene silencing. Located in cytoplasm. Part of RISC complex. Expressed in several structures, including gonad; hypodermis; neurons; somatic cell; and ventral nerve cord. Is an ortholog of human AGO2 (argonaute RISC catalytic component 2). WB:WBGene00000107 alh-1 Predicted to enable aldehyde dehydrogenase (NAD+) activity. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); diabetes mellitus (multiple); and liver disease (multiple). Is an ortholog of human ALDH1B1 (aldehyde dehydrogenase 1 family member B1). WB:WBGene00000108 alh-2 Predicted to enable aldehyde dehydrogenase (NAD+) activity. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); diabetes mellitus (multiple); and liver disease (multiple). Is an ortholog of human ALDH1B1 (aldehyde dehydrogenase 1 family member B1). WB:WBGene00000109 alh-3 Predicted to enable aldehyde dehydrogenase (NAD+) activity and formyltetrahydrofolate dehydrogenase activity. Predicted to be involved in 10-formyltetrahydrofolate catabolic process; biosynthetic process; and one-carbon metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ALDH1L1 (aldehyde dehydrogenase 1 family member L1) and ALDH1L2 (aldehyde dehydrogenase 1 family member L2). WB:WBGene00000110 alh-4 Predicted to enable aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in cellular aldehyde metabolic process. Predicted to be located in cytoplasm. Expressed in hypodermis. Used to study Sjogren-Larsson syndrome. Human ortholog(s) of this gene implicated in Sjogren-Larsson syndrome and arteriosclerosis. Is an ortholog of human ALDH3A1 (aldehyde dehydrogenase 3 family member A1); ALDH3A2 (aldehyde dehydrogenase 3 family member A2); and ALDH3B1 (aldehyde dehydrogenase 3 family member B1). WB:WBGene00000111 alh-5 Predicted to enable aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in cellular aldehyde metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Sjogren-Larsson syndrome and arteriosclerosis. Is an ortholog of human ALDH3A1 (aldehyde dehydrogenase 3 family member A1); ALDH3A2 (aldehyde dehydrogenase 3 family member A2); and ALDH3B1 (aldehyde dehydrogenase 3 family member B1). WB:WBGene00000112 alh-6 Predicted to enable 1-pyrroline-5-carboxylate dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Predicted to be located in mitochondrial matrix. Expressed in head and tail. Human ortholog(s) of this gene implicated in hyperprolinemia type 2. Is an ortholog of human ALDH4A1 (aldehyde dehydrogenase 4 family member A1). WB:WBGene00000113 alh-7 Predicted to enable succinate-semialdehyde dehydrogenase (NAD+) activity. Predicted to be involved in gamma-aminobutyric acid catabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in succinic semialdehyde dehydrogenase deficiency. Is an ortholog of human ALDH5A1 (aldehyde dehydrogenase 5 family member A1). WB:WBGene00000114 alh-8 Predicted to enable malonate-semialdehyde dehydrogenase (acetylating) activity and methylmalonate-semialdehyde dehydrogenase (acylating) activity. Predicted to be involved in thymine catabolic process and valine catabolic process. Located in mitochondrion. Is an ortholog of human ALDH6A1 (aldehyde dehydrogenase 6 family member A1). WB:WBGene00000115 alh-9 Predicted to enable aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in cellular aldehyde metabolic process. Expressed in ABa and seam cell. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and pyridoxine-dependent epilepsy. Is an ortholog of human ALDH7A1 (aldehyde dehydrogenase 7 family member A1). WB:WBGene00000116 alh-10 Predicted to enable oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. Is an ortholog of human ALDH8A1 (aldehyde dehydrogenase 8 family member A1). WB:WBGene00000117 alh-11 Predicted to enable 4-trimethylammoniobutyraldehyde dehydrogenase activity and aminobutyraldehyde dehydrogenase activity. Is an ortholog of human ALDH9A1 (aldehyde dehydrogenase 9 family member A1). WB:WBGene00000118 alh-12 Predicted to enable 4-trimethylammoniobutyraldehyde dehydrogenase activity and aminobutyraldehyde dehydrogenase activity. Is an ortholog of human ALDH9A1 (aldehyde dehydrogenase 9 family member A1). WB:WBGene00000119 ali-1 No description available WB:WBGene00000120 aly-1 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Is an ortholog of human ALYREF (Aly/REF export factor). WB:WBGene00000121 aly-2 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Is an ortholog of human ALYREF (Aly/REF export factor). WB:WBGene00000122 aly-3 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Is an ortholog of human ALYREF (Aly/REF export factor). WB:WBGene00000123 ama-1 Contributes to RNA polymerase II activity. Involved in embryo development; gastrulation; and mRNA transcription by RNA polymerase II. Located in chromosome and nuclear body. Part of euchromatin. Is an ortholog of human POLR2A (RNA polymerase II subunit A). WB:WBGene00000124 ama-2 No description available WB:WBGene00000125 amo-1 No description available WB:WBGene00000126 amo-2 No description available WB:WBGene00000127 amo-4 No description available WB:WBGene00000128 amo-5 No description available WB:WBGene00000129 amo-6 No description available WB:WBGene00000130 amo-7 No description available WB:WBGene00000131 amo-8 No description available WB:WBGene00000132 amo-9 No description available WB:WBGene00000133 amt-1 Predicted to enable ammonium transmembrane transporter activity. Predicted to be involved in ammonium homeostasis and ammonium transmembrane transport. Predicted to be located in membrane. WB:WBGene00000134 amt-2 Predicted to enable ammonium transmembrane transporter activity. Predicted to be involved in ammonium homeostasis and ammonium transmembrane transport. Predicted to be located in membrane. WB:WBGene00000135 amt-3 Predicted to enable ammonium transmembrane transporter activity. Predicted to be involved in ammonium homeostasis and ammonium transmembrane transport. Predicted to be located in membrane. Expressed in head and tail. WB:WBGene00000136 amt-4 Predicted to enable ammonium transmembrane transporter activity. Predicted to be involved in ammonium homeostasis and ammonium transmembrane transport. Predicted to be located in plasma membrane. WB:WBGene00000137 amx-1 Enables FAD-dependent H3K4me/H3K4me3 demethylase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in chemosensory neurons. Human ortholog(s) of this gene implicated in retinoblastoma. Is an ortholog of human KDM1B (lysine demethylase 1B). WB:WBGene00000138 amx-2 Predicted to enable oxidoreductase activity. Expressed in several structures, including HSN; anus; pharyngeal muscle cell; rectal epithelium; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Brunner Syndrome; alcohol use disorder; and panic disorder. Is an ortholog of human MAOA (monoamine oxidase A). WB:WBGene00000139 amx-3 Predicted to enable polyamine oxidase activity. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human PAOX (polyamine oxidase) and SMOX (spermine oxidase). WB:WBGene00000140 anc-1 Predicted to enable actin binding activity and kinesin binding activity. Involved in cytoskeleton organization; nucleus organization; and pronuclear migration. Located in nuclear envelope and perinuclear region of cytoplasm. Expressed in several structures, including body wall musculature; intestinal cell; and vulval muscle. Used to study Emery-Dreifuss muscular dystrophy. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-3; autosomal dominant Emery-Dreifuss muscular dystrophy 4; autosomal dominant Emery-Dreifuss muscular dystrophy 5; autosomal recessive spinocerebellar ataxia 8; and bipolar disorder. Is an ortholog of human SYNE1 (spectrin repeat containing nuclear envelope protein 1). WB:WBGene00000141 anx-1 No description available WB:WBGene00000142 aos-1 Contributes to SUMO activating enzyme activity. Involved in protein sumoylation. Predicted to be located in cytoplasm. Predicted to be part of SUMO activating enzyme complex. Is an ortholog of human SAE1 (SUMO1 activating enzyme subunit 1). WB:WBGene00000143 apc-2 Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in metaphase/anaphase transition of mitotic cell cycle. Predicted to be part of anaphase-promoting complex. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; lung disease (multiple); and primary angle-closure glaucoma. Is an ortholog of human ANAPC2 (anaphase promoting complex subunit 2). WB:WBGene00000144 apc-10 Predicted to be involved in cell division; meiotic cell cycle; and protein metabolic process. Predicted to be part of anaphase-promoting complex. Is an ortholog of human ANAPC10 (anaphase promoting complex subunit 10). WB:WBGene00000145 apc-11 Enables ubiquitin-protein transferase activity. Involved in anaphase-promoting complex-dependent catabolic process; embryo development; and meiotic chromosome segregation. Predicted to be located in nucleus. Predicted to be part of anaphase-promoting complex. Expressed in germ line. Is an ortholog of human ANAPC11 (anaphase promoting complex subunit 11). WB:WBGene00000146 ape-1 Enables p53 binding activity. Involved in negative regulation of apoptotic process. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including neurons and ventral nerve cord. Is an ortholog of human PPP1R13B (protein phosphatase 1 regulatory subunit 13B) and TP53BP2 (tumor protein p53 binding protein 2). WB:WBGene00000147 aph-1 Predicted to enable protein-macromolecule adaptor activity. Involved in several processes, including cell differentiation; pharynx development; and protein localization to cell surface. Predicted to be located in endoplasmic reticulum. Predicted to be part of gamma-secretase complex. Human ortholog(s) of this gene implicated in coronary artery disease. Is an ortholog of human APH1A (aph-1 homolog A, gamma-secretase subunit) and APH1B (aph-1 homolog B, gamma-secretase subunit). WB:WBGene00000148 aph-2 Involved in several processes, including Notch signaling pathway; egg-laying behavior; and pharynx development. Located in plasma membrane. Expressed in oocyte. Human ortholog(s) of this gene implicated in Alzheimer's disease; hidradenitis suppurativa; and schizophrenia. Is an ortholog of human NCSTN (nicastrin). WB:WBGene00000149 apl-1 Predicted to enable heparin binding activity and transition metal ion binding activity. Involved in body morphogenesis; ecdysis, collagen and cuticulin-based cuticle; and nematode larval development. Located in cytoplasmic vesicle; neuron projection; and neuronal cell body. Expressed in several structures, including epithelial cell; excretory cell; hermaphrodite gonad; neurons; and somatic nervous system. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in several diseases, including APP-related cerebral amyloid angiopathy; Alzheimer's disease 1; traumatic brain injury; and visual epilepsy. Is an ortholog of human APLP2 (amyloid beta precursor like protein 2). WB:WBGene00000150 apm-1 Predicted to enable clathrin adaptor activity. Involved in apical protein localization. Predicted to be located in clathrin-coated vesicle. Predicted to be part of clathrin adaptor complex. Expressed in head; nerve ring; tail; and vulva. Is an ortholog of human AP1M1 (adaptor related protein complex 1 subunit mu 1) and AP1M2 (adaptor related protein complex 1 subunit mu 2). WB:WBGene00000151 apn-1 Enables 3'-tyrosyl-DNA phosphodiesterase activity; DNA-(apurinic or apyrimidinic site) endonuclease activity; and double-stranded DNA 3'-5' DNA exonuclease activity. Involved in base-excision repair. Located in nucleus. Expressed in hermaphrodite gonad and male gonad. WB:WBGene00000152 apo-2 No description available WB:WBGene00000153 apo-3 No description available WB:WBGene00000154 apo-4 No description available WB:WBGene00000155 app-1 Enables metalloaminopeptidase activity; protein homodimerization activity; and zinc ion binding activity. Involved in proteolysis involved in protein catabolic process. Located in cytoplasm. Expressed in intestine. Human ortholog(s) of this gene implicated in acquired angioedema. Is an ortholog of human XPNPEP1 (X-prolyl aminopeptidase 1). WB:WBGene00000156 apr-1 Enables beta-catenin binding activity. Involved in several processes, including embryonic morphogenesis; regulation of Wnt signaling pathway; and regulation of multicellular organismal development. Located in adherens junction; cell cortex; and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; distal tip cell; and excretory cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Sotos syndrome 3; carcinoma (multiple); and gastrointestinal system cancer (multiple). Is an ortholog of human APC (APC regulator of WNT signaling pathway) and APC2 (APC regulator of WNT signaling pathway 2). WB:WBGene00000157 aps-2 Predicted to enable clathrin binding activity. Involved in several processes, including body morphogenesis; clathrin-dependent endocytosis; and nematode larval development. Predicted to be located in intracellular membrane-bounded organelle. Expressed in neurons. Human ortholog(s) of this gene implicated in familial hypocalciuric hypercalcemia 3. Is an ortholog of human AP2S1 (adaptor related protein complex 2 subunit sigma 1). WB:WBGene00000158 apg-1 Predicted to enable clathrin adaptor activity. Involved in apical protein localization and protein secretion. Predicted to be located in Golgi apparatus; cytoplasmic vesicle; and membrane. Predicted to be part of AP-1 adaptor complex. Is an ortholog of human AP1G1 (adaptor related protein complex 1 subunit gamma 1). WB:WBGene00000159 aps-1 Involved in apical protein localization. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of AP-1 adaptor complex. Human ortholog(s) of this gene implicated in MEDNIK syndrome; psoriasis 15; and syndromic X-linked intellectual disability 5. Is an ortholog of human AP1S1 (adaptor related protein complex 1 subunit sigma 1) and AP1S2 (adaptor related protein complex 1 subunit sigma 2). WB:WBGene00000160 apb-1 Predicted to enable clathrin binding activity. Involved in embryo development and receptor-mediated endocytosis. Predicted to be located in cytoplasm and membrane. Predicted to be part of clathrin adaptor complex. Is an ortholog of human AP1B1 (adaptor related protein complex 1 subunit beta 1). WB:WBGene00000161 apa-2 Enables GTPase activating protein binding activity. Involved in clathrin-dependent endocytosis; embryo development; and protein localization. Located in clathrin-coated endocytic vesicle and presynaptic periactive zone. Expressed in several structures, including anterior gonad arm; germ line; intestine; nervous system; and vulva. Is an ortholog of human AP2A1 (adaptor related protein complex 2 subunit alpha 1) and AP2A2 (adaptor related protein complex 2 subunit alpha 2). WB:WBGene00000162 apd-3 Predicted to be involved in intracellular transport and synaptic vesicle membrane organization. Predicted to be located in endosome membrane; presynaptic endosome; and terminal bouton. Predicted to be part of AP-3 adaptor complex. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome. Is an ortholog of human AP3D1 (adaptor related protein complex 3 subunit delta 1). WB:WBGene00000163 apb-3 Involved in embryo development and lysosome organization. Predicted to be located in clathrin-coated vesicle membrane. Predicted to be part of AP-3 adaptor complex. Expressed in motor neurons. Human ortholog(s) of this gene implicated in several diseases, including Hermansky-Pudlak syndrome 2; developmental and epileptic encephalopathy 48; and pulmonary fibrosis. Is an ortholog of human AP3B2 (adaptor related protein complex 3 subunit beta 2). WB:WBGene00000164 apm-3 Involved in lipid storage and lysosome organization. Predicted to be located in cytoplasmic vesicle. Predicted to be part of clathrin adaptor complex. Expressed in muscle cell; pharynx; spermatheca; and vulva. Is an ortholog of human AP3M1 (adaptor related protein complex 3 subunit mu 1). WB:WBGene00000165 aps-3 Predicted to be involved in vesicle-mediated transport. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human AP3S1 (adaptor related protein complex 3 subunit sigma 1) and AP3S2 (adaptor related protein complex 3 subunit sigma 2). WB:WBGene00000166 apt-9 Predicted to enable small GTPase binding activity. Involved in protein secretion. Predicted to be located in trans-Golgi network. Is an ortholog of human GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1). WB:WBGene00000168 apx-1 Predicted to enable Notch binding activity. Involved in several processes, including lateral inhibition; regulation of germ cell proliferation; and regulation of vulval development. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Expressed in several structures, including P6.paa; P6.pap; P6.ppa; non-striated muscle; and vulva. Human ortholog(s) of this gene implicated in spondylocostal dysostosis 1. Is an ortholog of human DLL3 (delta like canonical Notch ligand 3). WB:WBGene00000169 aqp-1 Enables channel activity. Involved in defense response to Gram-negative bacterium; glycerol transmembrane transport; and innate immune response. Located in basolateral plasma membrane. Expressed in intestine and pharynx. Human ortholog(s) of this gene implicated in several diseases, including brain edema; inflammatory bowel disease (multiple); and morbid obesity. Is an ortholog of several human genes including AQP3 (aquaporin 3 (Gill blood group)); AQP7 (aquaporin 7); and AQP9 (aquaporin 9). WB:WBGene00000170 aqp-2 Enables water channel activity. Involved in water transport. Predicted to be located in basolateral plasma membrane. Expressed in excretory cell; hypodermis; and muscle cell. Human ortholog(s) of this gene implicated in several diseases, including brain edema; inflammatory bowel disease (multiple); and morbid obesity. Is an ortholog of several human genes including AQP3 (aquaporin 3 (Gill blood group)); AQP7 (aquaporin 7); and AQP9 (aquaporin 9). WB:WBGene00000171 aqp-3 Enables water channel activity. Involved in glycerol transmembrane transport and water transport. Predicted to be located in basolateral plasma membrane. Expressed in excretory cell; intestine; and vas deferens. Human ortholog(s) of this gene implicated in several diseases, including brain edema; inflammatory bowel disease (multiple); and morbid obesity. Is an ortholog of several human genes including AQP3 (aquaporin 3 (Gill blood group)); AQP7 (aquaporin 7); and AQP9 (aquaporin 9). WB:WBGene00000172 aqp-4 Enables water channel activity. Involved in water transport. Located in apical plasma membrane. Expressed in intestine. Is an ortholog of human AQP8 (aquaporin 8). WB:WBGene00000173 aqp-5 Predicted to enable water channel activity. Predicted to be involved in water transport. Located in cell surface. Expressed in I1L; I1R; I2L; and I2R. Is an ortholog of human AQP8 (aquaporin 8). WB:WBGene00000174 aqp-6 Enables water channel activity. Involved in water transport. Located in neuronal cell body and non-motile cilium. Expressed in IL1 neuron. Is an ortholog of human AQP8 (aquaporin 8). WB:WBGene00000175 aqp-7 Enables water channel activity. Involved in glycerol transmembrane transport and water transport. Predicted to be located in basolateral plasma membrane. Expressed in muscle cell. WB:WBGene00000176 aqp-8 Predicted to enable glycerol channel activity and water channel activity. Predicted to be involved in glycerol transmembrane transport and water transport. Located in cell surface. Expressed in several structures, including excretory system; germ line; intestinal cell; non-striated muscle; and ray. Human ortholog(s) of this gene implicated in several diseases, including brain edema; inflammatory bowel disease (multiple); and morbid obesity. Is an ortholog of several human genes including AQP3 (aquaporin 3 (Gill blood group)); AQP7 (aquaporin 7); and AQP9 (aquaporin 9). WB:WBGene00000177 aqp-9 Predicted to enable channel activity. Predicted to be involved in transmembrane transport. Predicted to be located in cytoplasm. Is an ortholog of human AQP11 (aquaporin 11). WB:WBGene00000178 aqp-10 Predicted to enable channel activity. Involved in innate immune response. Predicted to be located in cytoplasm. Is an ortholog of human AQP11 (aquaporin 11); AQP12A (aquaporin 12A); and AQP12B (aquaporin 12B). WB:WBGene00000179 aqp-11 Predicted to enable channel activity. Predicted to be involved in transmembrane transport. Predicted to be located in cytoplasm. Is an ortholog of human AQP11 (aquaporin 11); AQP12A (aquaporin 12A); and AQP12B (aquaporin 12B). WB:WBGene00000180 arc-1 Predicted to enable GTPase activity; ion binding activity; and transferase activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in lysosomal membrane and plasma membrane. Is an ortholog of human TRIM23 (tripartite motif containing 23). WB:WBGene00000181 ard-1 Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)] activity. Predicted to be involved in androgen metabolic process; estrogen metabolic process; and fatty acid metabolic process. Predicted to be located in mitochondrion. Expressed in hypodermis. Human ortholog(s) of this gene implicated in Alzheimer's disease; osteosarcoma; pheochromocytoma; and syndromic X-linked intellectual disability type 10. Is an ortholog of human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10). WB:WBGene00000182 arf-1 Predicted to enable GTP binding activity and GTPase activity. Involved in several processes, including oocyte development; regulation of apoptotic process involved in development; and regulation of receptor-mediated endocytosis. Located in endoplasmic reticulum. Expressed in pharyngeal muscle cell; uterus; ventral nerve cord; and vulval precursor cell. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is an ortholog of human ARF1 (ADP ribosylation factor 1) and ARF3 (ADP ribosylation factor 3). WB:WBGene00000183 arf-5 Predicted to enable GTP binding activity and GTPase activity. Involved in embryo development and germ cell development. Predicted to be located in plasma membrane. Expressed in several structures, including body wall musculature; intestine; pharyngeal muscle cell; ventral nerve cord; and vulva. Is an ortholog of human ARF5 (ADP ribosylation factor 5). WB:WBGene00000184 arf-6 Predicted to enable GTP binding activity and GTPase activity. Involved in negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; and positive regulation of endosome to plasma membrane protein transport. Located in basolateral plasma membrane; cytoplasmic side of apical plasma membrane; and recycling endosome membrane. Expressed in several structures, including excretory cell; intestine; pharyngeal muscle cell; ventral nerve cord; and vulva. Is an ortholog of human ARF6 (ADP ribosylation factor 6). WB:WBGene00000185 arg-1 Predicted to enable Notch binding activity. Predicted to be involved in cell communication. Predicted to be located in membrane. Expressed in several structures, including head mesodermal cell; male distal tip cell; non-striated muscle; somatic gonad precursor; and tail. WB:WBGene00000186 ark-1 Predicted to enable protein tyrosine kinase activity. Involved in embryo development; negative regulation of epidermal growth factor receptor signaling pathway; and negative regulation of vulval development. WB:WBGene00000187 arl-1 Predicted to enable GTP binding activity and GTPase activity. Involved in positive regulation of nematode male tail tip morphogenesis. Predicted to be located in Golgi apparatus. Expressed in hyp10; hyp11; hyp8; hyp9; and ventral nerve cord. Is an ortholog of human ARL1 (ADP ribosylation factor like GTPase 1). WB:WBGene00000188 arl-3 Predicted to enable GTP binding activity. Predicted to be involved in cilium assembly. Predicted to be located in cytoplasm and microtubule cytoskeleton. Expressed in head neurons and tail neurons. Human ortholog(s) of this gene implicated in Joubert syndrome and retinitis pigmentosa 83. Is an ortholog of human ARL3 (ADP ribosylation factor like GTPase 3). WB:WBGene00000189 arl-5 Predicted to enable GTP binding activity and GTPase activity. Involved in microtubule cytoskeleton organization. Predicted to be located in trans-Golgi network. Is an ortholog of human ARL5A (ADP ribosylation factor like GTPase 5A) and ARL5B (ADP ribosylation factor like GTPase 5B). WB:WBGene00000190 warf-1 Predicted to enable GTP binding activity and GTPase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. WB:WBGene00000191 arl-7 Enriched in SIA; intestine; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Sodium Chloride; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00000192 arl-8 Predicted to enable GTP binding activity and GTPase activity. Involved in axo-dendritic transport; endosome to lysosome transport; and regulation of anterograde synaptic vesicle transport. Located in lysosome; presynaptic active zone; and synaptic vesicle. Expressed in coelomocyte and muscle cell. Is an ortholog of human ARL8A (ADP ribosylation factor like GTPase 8A). WB:WBGene00000193 arl-6 Enables GTPase activity. Involved in intracellular transport. Located in axoneme; cytosol; and dendrite. Expressed in ciliated neurons. Used to study Bardet-Biedl syndrome and ciliopathy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 1; Bardet-Biedl syndrome 3; and retinitis pigmentosa 55. Is an ortholog of human ARL6 (ADP ribosylation factor like GTPase 6). WB:WBGene00000195 arr-1 Predicted to enable G protein-coupled receptor binding activity. Involved in positive regulation of growth rate. Predicted to be located in cytoplasm. Expressed in HSN; amphid neurons; somatic nervous system; and tail. Human ortholog(s) of this gene implicated in eye disease (multiple); major depressive disorder; and portal hypertension. Is an ortholog of human ARRB1 (arrestin beta 1) and ARRB2 (arrestin beta 2). WB:WBGene00000196 aars-1 Predicted to enable alanine-tRNA ligase activity and aminoacyl-tRNA editing activity. Predicted to be involved in alanyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 8 and progressive leukoencephalopathy with ovarian failure. Is an ortholog of human AARS2 (alanyl-tRNA synthetase 2, mitochondrial). WB:WBGene00000197 aars-2 Predicted to enable alanine-tRNA ligase activity and aminoacyl-tRNA editing activity. Predicted to be involved in alanyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Expressed widely. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease axonal type 2N; developmental and epileptic encephalopathy 29; and trichothiodystrophy. Is an ortholog of human AARS1 (alanyl-tRNA synthetase 1). WB:WBGene00000198 art-1 Predicted to enable oxidoreductase activity. Predicted to be involved in very long-chain fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 14 and catecholaminergic polymorphic ventricular tachycardia 3. Is an ortholog of human TECR (trans-2,3-enoyl-CoA reductase). WB:WBGene00000199 arx-1 Predicted to enable ATP binding activity and actin binding activity. Predicted to contribute to actin filament binding activity. Involved in Arp2/3 complex-mediated actin nucleation; embryonic morphogenesis; and epithelial cell migration. Located in cell leading edge and cytoplasm. Expressed in hypodermis. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glioblastoma; and opisthorchiasis. Is an ortholog of human ACTR3 (actin related protein 3). WB:WBGene00000200 arx-2 Predicted to enable ATP binding activity and actin binding activity. Predicted to contribute to actin filament binding activity. Involved in Arp2/3 complex-mediated actin nucleation; embryonic morphogenesis; and epithelial cell migration. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of Arp2/3 protein complex. Expressed in Q cell; anchor cell; apoptotic cell; seam cell; and socket cell. Human ortholog(s) of this gene implicated in colorectal carcinoma. Is an ortholog of human ACTR2 (actin related protein 2). WB:WBGene00000201 arx-3 Predicted to enable actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation. Predicted to be located in actin cytoskeleton and cytoplasm. Predicted to be part of Arp2/3 protein complex. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); immunodeficiency 71; and myelodysplastic syndrome. Is an ortholog of human ARPC1A (actin related protein 2/3 complex subunit 1A) and ARPC1B (actin related protein 2/3 complex subunit 1B). WB:WBGene00000202 exos-4.2 Predicted to be involved in RNA metabolic process. Predicted to be located in nucleolus. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is an ortholog of human EXOSC6 (exosome component 6). WB:WBGene00000203 arx-5 Predicted to enable actin binding activity. Predicted to contribute to actin filament binding activity. Involved in epithelial cell migration and morphogenesis of embryonic epithelium. Located in striated muscle dense body. Human ortholog(s) of this gene implicated in diabetes mellitus. Is an ortholog of human ARPC3 (actin related protein 2/3 complex subunit 3). WB:WBGene00000204 arx-6 Predicted to enable actin filament binding activity. Involved in epithelial cell migration and morphogenesis of embryonic epithelium. Predicted to be located in actin cytoskeleton and cytoplasm. Predicted to be part of Arp2/3 protein complex. Human ortholog(s) of this gene implicated in Down syndrome. Is an ortholog of human ARPC4 (actin related protein 2/3 complex subunit 4). WB:WBGene00000205 arx-7 Predicted to enable actin filament binding activity. Involved in Arp2/3 complex-mediated actin nucleation; epithelial cell migration; and morphogenesis of embryonic epithelium. Located in cytoplasm. Expressed in anchor cell; hypodermis; and linker cell. Human ortholog(s) of this gene implicated in lung squamous cell carcinoma. Is an ortholog of human ARPC5 (actin related protein 2/3 complex subunit 5) and ARPC5L (actin related protein 2/3 complex subunit 5 like). WB:WBGene00000206 asb-1 Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Located in mitochondrion and non-motile cilium. Expressed in germ line. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma and hepatocellular carcinoma. Is an ortholog of human ATP5PB (ATP synthase peripheral stalk-membrane subunit b). WB:WBGene00000207 asb-2 Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Expressed in several structures, including gonad. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma and hepatocellular carcinoma. Is an ortholog of human ATP5PB (ATP synthase peripheral stalk-membrane subunit b). WB:WBGene00000208 trip-4 Predicted to enable transcription coactivator activity. Involved in dauer larval development. Predicted to be located in nucleus. Is an ortholog of human TRIP4 (thyroid hormone receptor interactor 4). WB:WBGene00000209 asg-1 Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in mitochondrial membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human ATP5MG (ATP synthase membrane subunit g). WB:WBGene00000210 asg-2 Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Located in mitochondrion and non-motile cilium. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human ATP5MG (ATP synthase membrane subunit g). WB:WBGene00000211 asm-1 Enables sphingomyelin phosphodiesterase activity. Involved in ceramide biosynthetic process and sphingomyelin catabolic process. Located in extracellular region and lysosome. Human ortholog(s) of this gene implicated in Niemann-Pick disease type A and Niemann-Pick disease type B. Is an ortholog of human SMPD1 (sphingomyelin phosphodiesterase 1). WB:WBGene00000212 asm-2 Enables sphingomyelin phosphodiesterase activity. Involved in ceramide biosynthetic process and sphingomyelin catabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in Niemann-Pick disease type A and Niemann-Pick disease type B. Is an ortholog of human SMPD1 (sphingomyelin phosphodiesterase 1). WB:WBGene00000213 asm-3 Predicted to enable acid sphingomyelin phosphodiesterase activity. Involved in lipid droplet disassembly. Predicted to be located in extracellular space and lysosome. Human ortholog(s) of this gene implicated in Niemann-Pick disease type A and Niemann-Pick disease type B. Is an ortholog of human SMPD1 (sphingomyelin phosphodiesterase 1). WB:WBGene00000214 asp-1 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Located in cytoplasm and external side of apical plasma membrane. Expressed in intestinal cell and intestine. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human PGC (progastricsin) and REN (renin). WB:WBGene00000215 asp-2 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. WB:WBGene00000216 asp-3 Predicted to enable aspartic-type endopeptidase activity. Involved in programmed necrotic cell death. Located in lysosome. Expressed in intestine and uterus. Is an ortholog of human NAPSA (napsin A aspartic peptidase). WB:WBGene00000217 asp-4 Predicted to enable aspartic-type endopeptidase activity. Involved in programmed necrotic cell death. Located in lysosome. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; and neuronal ceroid lipofuscinosis 10. Is an ortholog of human CTSD (cathepsin D). WB:WBGene00000218 asp-5 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human REN (renin). WB:WBGene00000219 asp-6 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Located in extracellular space. Expressed in hypodermal cell; intestine; muscle cell; pharynx; and pseudocoelom. WB:WBGene00000220 atf-2 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and protein heterodimerization activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in digestive tract; egg-laying apparatus; excretory system; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in severe acute respiratory syndrome. Is an ortholog of human NFIL3 (nuclear factor, interleukin 3 regulated) and NFILZ (NFIL3 like basic leucine zipper). WB:WBGene00000221 atf-4 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Human ortholog(s) of this gene implicated in prostate carcinoma. Is an ortholog of human ATF4 (activating transcription factor 4) and ATF5 (activating transcription factor 5). WB:WBGene00000222 atf-6 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in ATF6-mediated unfolded protein response and positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response. Predicted to be located in nucleus. Expressed in several structures, including intestine; muscle cell; pharyngeal gland cell; rectum; and vulva. Human ortholog(s) of this gene implicated in achromatopsia 7. Is an ortholog of human ATF6 (activating transcription factor 6) and ATF6B (activating transcription factor 6 beta). WB:WBGene00000223 atf-7 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and mitogen-activated protein kinase binding activity. Involved in several processes, including defense response to bacterium; regulation of innate immune response; and regulation of transcription by RNA polymerase II. Acts upstream of or within serotonin biosynthetic process. Located in nucleus. Part of chromatin. Expressed in body wall musculature; hypodermis; intestine; neurons; and rectal epithelial cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; colorectal cancer; and schizophrenia. Is an ortholog of human ATF2 (activating transcription factor 2); ATF7 (activating transcription factor 7); and CREB5 (cAMP responsive element binding protein 5). WB:WBGene00000224 atgp-1 Predicted to enable hydrolase activity, acting on glycosyl bonds. Predicted to be involved in carbohydrate metabolic process. Located in plasma membrane. Human ortholog(s) of this gene implicated in cystinuria. Is an ortholog of human SLC3A1 (solute carrier family 3 member 1). WB:WBGene00000225 atgp-2 Contributes to L-amino acid transmembrane transporter activity. Involved in amino acid transmembrane transport. Located in plasma membrane. Part of amino acid transport complex. Human ortholog(s) of this gene implicated in cystinuria. Is an ortholog of human SLC3A1 (solute carrier family 3 member 1). WB:WBGene00000226 atl-1 Predicted to enable 1-phosphatidylinositol-3-kinase activity and protein serine/threonine kinase activity. Involved in DNA damage checkpoint signaling; embryo development; and meiotic chromosome segregation. Located in nucleus. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Seckel syndrome 1; gastrointestinal system cancer (multiple); and pancreatic cancer. Is an ortholog of human ATR (ATR serine/threonine kinase). WB:WBGene00000227 atm-1 Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Involved in response to ionizing radiation. Part of chromatin. Used to study ataxia telangiectasia. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; breast cancer (multiple); gastrointestinal system cancer (multiple); and lung carcinoma (multiple). Is an ortholog of human ATM (ATM serine/threonine kinase). WB:WBGene00000228 atn-1 Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and muscle cell development. Located in dense body; striated muscle dense body; and striated muscle thin filament. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including congenital myopathy 8; focal segmental glomerulosclerosis 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of human ACTN2 (actinin alpha 2) and ACTN3 (actinin alpha 3). WB:WBGene00000229 atp-2 Enables protein domain specific binding activity. Involved in several processes, including determination of adult lifespan; inductive cell migration; and pharyngeal pumping. Located in mitochondrion and non-motile cilium. Expressed in HOB; head; ray neuron type B; and tail. Is an ortholog of human ATP5F1B (ATP synthase F1 subunit beta). WB:WBGene00000230 atp-3 Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Involved in determination of adult lifespan and proton motive force-driven mitochondrial ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase, stator stalk and proton-transporting ATP synthase complex, catalytic core F(1). Human ortholog(s) of this gene implicated in Alzheimer's disease and clear cell renal cell carcinoma. Is an ortholog of human ATP5PO (ATP synthase peripheral stalk subunit OSCP). WB:WBGene00000231 atx-2 Predicted to enable mRNA binding activity. Involved in several processes, including gamete generation; positive regulation of reproductive process; and regulation of cell cycle. Located in cytoplasm. Expressed in body wall musculature; dorsal nerve cord; germ line; gonad; and ventral nerve cord. Used to study autosomal dominant cerebellar ataxia. Human ortholog(s) of this gene implicated in late onset Parkinson's disease and spinocerebellar ataxia type 2. Is an ortholog of human ATXN2 (ataxin 2) and ATXN2L (ataxin 2 like). WB:WBGene00000232 avr-14 Enables extracellularly glutamate-gated chloride channel activity. Involved in several processes, including locomotion involved in locomotory behavior; regulation of pharyngeal pumping; and response to xenobiotic stimulus. Located in membrane. Expressed in head; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in hyperekplexia 1 and syndromic X-linked intellectual disability Pilgorge type. Is an ortholog of human GLRA1 (glycine receptor alpha 1); GLRA2 (glycine receptor alpha 2); and GLRA3 (glycine receptor alpha 3). WB:WBGene00000233 avr-15 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Involved in action potential; locomotion involved in locomotory behavior; and regulation of pharyngeal pumping. Predicted to be located in neuron projection and synapse. Expressed in motor neurons; pharynx; preanal ganglion neurons; somatic nervous system; and in male. Human ortholog(s) of this gene implicated in hyperekplexia 2 and syndromic X-linked intellectual disability Pilgorge type. Is an ortholog of human GLRA2 (glycine receptor alpha 2); GLRA3 (glycine receptor alpha 3); and GLRB (glycine receptor beta). WB:WBGene00000234 bac-1 No description available WB:WBGene00000235 baf-1 Predicted to enable double-stranded DNA binding activity and identical protein binding activity. Involved in several processes, including chromosome segregation; embryo development; and response to X-ray. Located in condensed chromosome, centromeric region; cytoplasm; and nucleus. Used to study muscular dystrophy. Human ortholog(s) of this gene implicated in Nestor-Guillermo progeria syndrome and hepatocellular carcinoma. Is an ortholog of human BANF1 (BAF nuclear assembly factor 1). WB:WBGene00000236 bag-1 Enables ATPase activator activity. Predicted to be involved in chaperone cofactor-dependent protein refolding and protein stabilization. Predicted to be located in cytosol; membrane; and nucleus. Human ortholog(s) of this gene implicated in breast cancer and reproductive organ cancer (multiple). Is an ortholog of human BAG1 (BAG cochaperone 1). WB:WBGene00000237 bam-2 Predicted to be involved in nervous system development. Located in plasma membrane. Expressed in head neurons; somatic gonad; tail neurons; ventral cord neurons; and vulF. WB:WBGene00000238 bar-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription coactivator activity. Involved in several processes, including nematode larval development; regulation of locomotion; and reproductive behavior. Located in several cellular components, including adherens junction; cytosol; and nucleus. Expressed in several structures, including gonad; intestine; and vulva. WB:WBGene00000239 bas-1 Predicted to enable L-dopa decarboxylase activity. Involved in several processes, including locomotion involved in locomotory behavior; phenol-containing compound biosynthetic process; and reproductive behavior. Predicted to be located in cytoplasm. Expressed in dopaminergic neurons; serotonergic neurons; socket cell; tail; and in male. Used to study cocaine abuse and nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including aromatic L-amino acid decarboxylase deficiency; bipolar disorder; and hyperinsulinism. Is an ortholog of human DDC (dopa decarboxylase). WB:WBGene00000240 pah-1 Enables phenylalanine 4-monooxygenase activity and tryptophan 5-monooxygenase activity. Involved in several processes, including aromatic amino acid metabolic process; determination of adult lifespan; and melanin biosynthetic process. Predicted to be located in cytoplasm. Expressed in hypodermis; seam cell; and tail. Used to study phenylketonuria. Human ortholog(s) of this gene implicated in intellectual disability and phenylketonuria. Is an ortholog of human PAH (phenylalanine hydroxylase). WB:WBGene00000241 bbs-1 Predicted to enable patched binding activity and smoothened binding activity. Involved in non-motile cilium assembly. Acts upstream of or within intraciliary retrograde transport and protein localization to cilium. Located in axoneme; ciliary basal body; and neuron projection. Expressed in ciliated neurons and sensory neurons. Used to study Bardet-Biedl syndrome; alcohol use disorder; and obesity. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 1 and obesity. Is an ortholog of human BBS1 (Bardet-Biedl syndrome 1). WB:WBGene00000242 bbs-2 Involved in non-motile cilium assembly. Located in ciliary basal body and neuron projection. Expressed in ciliated neurons and sensory neurons. Used to study Bardet-Biedl syndrome. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 2; obesity; and retinitis pigmentosa 74. Is an ortholog of human BBS2 (Bardet-Biedl syndrome 2). WB:WBGene00000244 bbs-8 Involved in several processes, including cilium organization; olfactory learning; and regulation of cellular localization. Located in cilium and dendrite terminus. Expressed in ciliated neurons; head; and sensory neurons. Used to study Bardet-Biedl syndrome and ciliopathy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 8 and retinitis pigmentosa 51. Is an ortholog of human TTC8 (tetratricopeptide repeat domain 8). WB:WBGene00000245 bca-1 Predicted to enable carbonate dehydratase activity and zinc ion binding activity. Acts upstream of or within IRE1-mediated unfolded protein response. WB:WBGene00000246 bcc-1 Predicted to enable RNA binding activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in diffuse cystic renal dysplasia. Is an ortholog of human BICC1 (BicC family RNA binding protein 1). WB:WBGene00000247 bec-1 Involved in several processes, including determination of adult lifespan; gamete generation; and nematode male tail tip morphogenesis. Located in cytoplasmic vesicle and nucleus. Expressed in several structures, including intestine; nervous system; pharynx; tail; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Barrett's esophagus; Machado-Joseph disease; and adenocarcinoma (multiple). Is an ortholog of human BECN1 (beclin 1). WB:WBGene00000248 ben-1 Predicted to enable GTP binding activity and structural molecule activity. Predicted to be a structural constituent of cytoskeleton. Involved in chemosensory behavior and egg-laying behavior. Predicted to be located in cytoplasm and microtubule. Expressed in coelomocyte; epithelial cell; muscle cell; and nervous system. Human ortholog(s) of this gene implicated in brain disease (multiple) and congenital symmetric circumferential skin creases 1. Is an ortholog of human TUBB (tubulin beta class I) and TUBB4A (tubulin beta 4A class IVa). WB:WBGene00000249 bir-1 Predicted to enable metal ion binding activity. Involved in several processes, including chromosome organization; egg-laying behavior; and inductive cell migration. Located in condensed chromosome and spindle midzone. Expressed in egg-laying apparatus; hypodermis; pharynx; rectal muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ductal carcinoma in situ; and endometrial hyperplasia. Is an ortholog of human BIRC5 (baculoviral IAP repeat containing 5). WB:WBGene00000250 bir-2 Predicted to enable metal ion binding activity. Acts upstream of or within with a positive effect on germ cell proliferation. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endometrial hyperplasia; and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue. Is an ortholog of human BIRC2 (baculoviral IAP repeat containing 2); BIRC3 (baculoviral IAP repeat containing 3); and BIRC5 (baculoviral IAP repeat containing 5). WB:WBGene00000251 bli-1 Predicted to be a structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in medial layer of collagen and cuticulin-based cuticle extracellular matrix. Expressed in hyp7 syncytium and seam cell. Human ortholog(s) of this gene implicated in Stickler syndrome and multiple epiphyseal dysplasia 6. Is an ortholog of human COL27A1 (collagen type XXVII alpha 1 chain) and COL9A1 (collagen type IX alpha 1 chain). WB:WBGene00000252 bli-2 Predicted to be a structural constituent of collagen and cuticulin-based cuticle. Involved in collagen and cuticulin-based cuticle development. Predicted to be located in external encapsulating structure. Predicted to be part of collagen trimer. WB:WBGene00000253 bli-3 Enables NAD(P)H oxidase H2O2-forming activity; heme binding activity; and peroxidase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; defense response to other organism; and post-embryonic development. Located in plasma membrane. Expressed in hypodermis; intestine; and neurons. Used to study phenylketonuria. Human ortholog(s) of this gene implicated in cholera; inflammatory bowel disease (multiple); and thyroid dyshormonogenesis 6. Is an ortholog of human DUOX2 (dual oxidase 2). WB:WBGene00000254 bli-4 Predicted to enable serine-type endopeptidase activity. Involved in several processes, including chemosensory behavior; collagen and cuticulin-based cuticle development; and positive regulation of synaptic assembly at neuromuscular junction. Located in nucleus. Expressed in head; hypodermis; ventral cord neurons; and vulva. WB:WBGene00000255 bli-5 Enables serine-type endopeptidase activity. A structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle; protein catabolic process; and vulval development. Expressed in excretory cell; excretory duct; and vulva. WB:WBGene00000256 bli-6 Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000257 bmk-1 Predicted to enable plus-end-directed microtubule motor activity. Involved in negative regulation of mitotic spindle elongation. Located in spindle midzone and spindle pole. Human ortholog(s) of this gene implicated in microcephaly with or without chorioretinopathy, lymphedema, or mental retardation. Is an ortholog of human KIF11 (kinesin family member 11). WB:WBGene00000259 bpl-1 Predicted to enable biotin-[acetyl-CoA-carboxylase] ligase activity. Predicted to be involved in protein modification process. Predicted to be located in cytoplasm. Expressed in Psub1. Human ortholog(s) of this gene implicated in holocarboxylase synthetase deficiency. Is an ortholog of human HLCS (holocarboxylase synthetase). WB:WBGene00000260 bpr-1 No description available WB:WBGene00000261 bpr-2 No description available WB:WBGene00000262 bra-1 Enables signaling receptor binding activity. Involved in determination of adult lifespan and negative regulation of transforming growth factor beta receptor signaling pathway. Located in axon and dendrite. Expressed in neurons. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 30 and stomach cancer. Is an ortholog of human ZMYND11 (zinc finger MYND-type containing 11). WB:WBGene00000263 F23H11.5 Predicted to be located in membrane. Expressed in hypodermis; intestine; and pharyngeal muscle cell. WB:WBGene00000264 brc-1 Enables ubiquitin protein ligase activity. Involved in several processes, including DNA repair; cellular response to ionizing radiation; and nuclear chromosome segregation. Part of BRCA1-BARD1 complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of human BRCA1 (BRCA1 DNA repair associated). WB:WBGene00000265 brd-1 Enables ubiquitin protein ligase activity. Involved in DNA repair and protein ubiquitination. Part of BRCA1-BARD1 complex. Human ortholog(s) of this gene implicated in breast cancer and ovarian cancer. Is an ortholog of human BARD1 (BRCA1 associated RING domain 1). WB:WBGene00000266 bre-1 Enables GDP-mannose 4,6-dehydratase activity. Involved in GDP-L-fucose biosynthetic process; GDP-mannose metabolic process; and response to toxic substance. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Human ortholog(s) of this gene implicated in open-angle glaucoma. Is an ortholog of human GMDS (GDP-mannose 4,6-dehydratase). WB:WBGene00000267 bre-2 Predicted to enable acetylglucosaminyltransferase activity. Involved in response to toxic substance. Predicted to be located in membrane. WB:WBGene00000268 bre-3 Predicted to enable beta-1,4-mannosyltransferase activity. Involved in carbohydrate biosynthetic process and response to toxic substance. Located in cytoplasm. Expressed in head neurons. WB:WBGene00000269 bre-4 Enables beta-1,4-N-acetylgalactosaminyltransferase activity. Involved in positive regulation of Notch signaling pathway; protein glycosylation; and response to toxic substance. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IId and multiple sclerosis. Is an ortholog of human B4GALT1 (beta-1,4-galactosyltransferase 1) and B4GALT3 (beta-1,4-galactosyltransferase 3). WB:WBGene00000270 bre-5 Enables acetylglucosaminyltransferase activity. Involved in several processes, including carbohydrate biosynthetic process; positive regulation of Notch signaling pathway; and regulation of mesodermal cell fate specification. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human B3GALNT1 (beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)); B3GALT9 (beta-1,3-galactosyltransferase 9); and B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5). WB:WBGene00000271 brf-1 Predicted to enable RNA polymerase III general transcription initiation factor activity and RNA polymerase III type 3 promoter sequence-specific DNA binding activity. Predicted to be involved in DNA-templated transcription initiation and transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIIB complex and transcription preinitiation complex. Human ortholog(s) of this gene implicated in cerebellofaciodental syndrome. Is an ortholog of human BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit). WB:WBGene00000272 bro-1 Enables transcription corepressor activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of locomotion involved in locomotory behavior. Located in nucleus. Part of core-binding activity factor complex. Expressed in hypodermis; muscle cell; pharyngeal neurons; ray precursor cell; and uterine seam cell. Human ortholog(s) of this gene implicated in acute myelomonocytic leukemia and hepatocellular carcinoma. Is an ortholog of human CBFB (core-binding factor subunit beta). WB:WBGene00000273 brp-1 Predicted to be located in membrane. WB:WBGene00000274 btf-1 Predicted to enable ATP-dependent activity, acting on DNA and DNA binding activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus. Is an ortholog of human BTAF1 (B-TFIID TATA-box binding protein associated factor 1). WB:WBGene00000275 bub-1 Enables kinetochore binding activity. Involved in several processes, including meiotic cell cycle; positive regulation of nematode male tail tip morphogenesis; and protein localization to kinetochore involved in kinetochore assembly. Located in kinetochore. Expressed in seam cell. Human ortholog(s) of this gene implicated in colorectal cancer and primary autosomal recessive microcephaly. Is an ortholog of human BUB1 (BUB1 mitotic checkpoint serine/threonine kinase). WB:WBGene00000276 byn-1 Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in cytoplasm and nucleolus. Predicted to be part of preribosome, small subunit precursor. Is an ortholog of human BYSL (bystin like). WB:WBGene00000277 cab-1 Involved in chemical synaptic transmission; positive regulation of anterior/posterior axon guidance; and ventral cord development. Predicted to be located in membrane and synapse. Is an ortholog of human NPDC1 (neural proliferation, differentiation and control 1). WB:WBGene00000278 cad-1 Acts upstream of or within programmed necrotic cell death. WB:WBGene00000279 cah-1 Predicted to enable hydro-lyase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be located in extracellular region. Expressed in ciliated neurons; head ganglion; sensory neurons; and tail neurons. Is an ortholog of human CA10 (carbonic anhydrase 10) and CA11 (carbonic anhydrase 11). WB:WBGene00000280 cah-2 Predicted to enable hydro-lyase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be located in extracellular region. Expressed in intestine; muscle cell; neurons; pharynx; and vulva. Is an ortholog of human CA10 (carbonic anhydrase 10) and CA11 (carbonic anhydrase 11). WB:WBGene00000281 cah-3 Predicted to enable carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be located in cytoplasm. Expressed in pharynx; somatic cell; and vulva. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Is an ortholog of human CA14 (carbonic anhydrase 14) and CA4 (carbonic anhydrase 4). WB:WBGene00000282 cah-4 Enables carbonate dehydratase activity. Involved in small molecule metabolic process. Predicted to be located in cytoplasm. Expressed in several structures, including body wall musculature; enteric muscle; excretory cell; rectal muscle; and somatic nervous system. Is an ortholog of several human genes including CA1 (carbonic anhydrase 1); CA3 (carbonic anhydrase 3); and CA5A (carbonic anhydrase 5A). WB:WBGene00000283 cah-5 Predicted to enable carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be located in cytoplasm. Expressed in several structures, including body wall musculature; head neurons; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive osteopetrosis 3; cerebellar ataxia, mental retardation and dysequlibrium syndrome; and colorectal carcinoma. Is an ortholog of human CA1 (carbonic anhydrase 1) and CA13 (carbonic anhydrase 13). WB:WBGene00000284 cah-6 Predicted to enable carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be located in cytoplasm. Expressed in head neurons; nervous system; and tail neurons. Is an ortholog of human CA6 (carbonic anhydrase 6). WB:WBGene00000285 cal-1 Predicted to enable calcium ion binding activity. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human CALML3 (calmodulin like 3); CALML4 (calmodulin like 4); and CALML5 (calmodulin like 5). WB:WBGene00000286 cal-2 Predicted to enable calcium ion binding activity. Expressed in head neurons; hypodermis; and tail neurons. WB:WBGene00000287 cal-3 Predicted to enable calcium ion binding activity. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human CALML3 (calmodulin like 3); CALML4 (calmodulin like 4); and CALML5 (calmodulin like 5). WB:WBGene00000288 cal-4 Predicted to enable calcium ion binding activity. WB:WBGene00000289 cam-1 Enables Wnt-protein binding activity; frizzled binding activity; and transmembrane receptor protein tyrosine kinase activity. Involved in generation of neurons and neuroblast migration. Located in axon; neuromuscular junction; and somatodendritic compartment. Expressed in several structures, including QL.aa; head; neurons; pharynx; and seam cell. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive Robinow syndrome; autosomal recessive nonsyndromic deafness 108; and brachydactyly type B1. Is an ortholog of human ROR1 (receptor tyrosine kinase like orphan receptor 1). WB:WBGene00000290 cam-2 No description available WB:WBGene00000291 can-1 No description available WB:WBGene00000292 cap-1 Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and barbed-end actin filament capping. Part of dynactin complex. Human ortholog(s) of this gene implicated in male infertility. Is an ortholog of human CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1) and CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2). WB:WBGene00000293 cap-2 Enables actin filament binding activity. Involved in actin cytoskeleton organization and embryonic axis specification. Located in cytoplasm. Part of dynactin complex. Expressed in tail. Is an ortholog of human CAPZB (capping actin protein of muscle Z-line subunit beta). WB:WBGene00000294 cas-1 Predicted to enable actin binding activity and adenylate cyclase binding activity. Predicted to be involved in actin filament organization; cAMP-mediated signaling; and cell morphogenesis. Predicted to be located in cytoplasm. Expressed in body wall musculature; intestine; neurons; pharynx; and spermatheca. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CAP1 (cyclase associated actin cytoskeleton regulatory protein 1) and CAP2 (cyclase associated actin cytoskeleton regulatory protein 2). WB:WBGene00000295 cat-1 Enables dopamine:sodium symporter activity and serotonin:sodium:chloride symporter activity. Involved in dopamine metabolic process; feeding behavior; and monoamine transport. Located in synaptic vesicle. Expressed in gonad; nervous system; and in male. Used to study amphetamine abuse and cocaine abuse. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; type 1 diabetes mellitus; and von Hippel-Lindau disease. Is an ortholog of human SLC18A1 (solute carrier family 18 member A1) and SLC18A2 (solute carrier family 18 member A2). WB:WBGene00000296 cat-2 Enables tyrosine 3-monooxygenase activity. Involved in several processes, including cellular response to amphetamine; dopamine biosynthetic process from tyrosine; and male mating behavior. Located in axon. Expressed in dopaminergic neurons; socket cell; and in male. Used to study several diseases, including amphetamine abuse; cocaine abuse; and nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; artery disease (multiple); and obesity. Is an ortholog of human TH (tyrosine hydroxylase). WB:WBGene00000297 cat-3 No description available WB:WBGene00000298 cat-4 Enables GTP cyclohydrolase I activity. Involved in dopamine biosynthetic process from tyrosine; melanin biosynthetic process; and tetrahydrobiopterin biosynthetic process. Predicted to be located in cytoplasm. Expressed in several structures, including body wall musculature; dopaminergic neurons; hyp7 syncytium; intestinal cell; and serotonergic neurons. Human ortholog(s) of this gene implicated in several diseases, including BH4-deficient hyperphenylalaninemia B; diabetic angiopathy; and movement disease (multiple). Is an ortholog of human GCH1 (GTP cyclohydrolase 1). WB:WBGene00000299 cat-5 No description available WB:WBGene00000300 cat-6 Acts upstream of or within non-motile cilium assembly. WB:WBGene00000301 cav-1 Predicted to enable molecular adaptor activity. Involved in Ras protein signal transduction; meiotic cell cycle; and regulation of egg-laying behavior. Located in cytoplasm and cytoplasmic side of plasma membrane. Expressed in several structures, including germ cell; gonad arm; nervous system; pharynx; and tail. Human ortholog(s) of this gene implicated in several diseases, including distal muscular dystrophy Tateyama type; glaucoma (multiple); lipodystrophy (multiple); and systemic scleroderma (multiple). Is an ortholog of human CAV1 (caveolin 1). WB:WBGene00000302 cav-2 Enables lipid transporter activity. Involved in parturition and regulation of egg-laying behavior. Located in apical plasma membrane. WB:WBGene00000308 C04A11.t1 Is affected by several genes including prg-1; etr-1; and hlh-26 based on RNA-seq studies. WB:WBGene00000310 C05C9.t1 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00000311 C05C9.t2 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00000366 cbp-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; histone acetyltransferase activity; and lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Involved in several processes, including positive regulation of transcription by RNA polymerase II; regulation of distal tip cell migration; and spermatogenesis. Located in cytoplasm and nucleus. Expressed in alimentary system; distal tip cell; head; and tail. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Huntington's disease; Rubinstein-Taybi syndrome; and leukemia (multiple). Is an ortholog of human CREBBP (CREB binding protein). WB:WBGene00000367 cca-1 Predicted to enable low voltage-gated calcium channel activity. Involved in membrane depolarization; positive regulation of action potential; and regulation of pharyngeal pumping. Predicted to be located in neuron projection. Predicted to be part of voltage-gated sodium channel complex. Expressed in several structures, including alimentary muscle; distal tip cell; pharyngeal neurons; serotonergic neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including cerebellar ataxia type 42; childhood absence epilepsy; and primary hyperaldosteronism. Is an ortholog of human CACNA1I (calcium voltage-gated channel subunit alpha1 I). WB:WBGene00000368 ccb-1 Predicted to enable high voltage-gated calcium channel activity. Involved in positive regulation of locomotion; regulation of calcium ion transport; and striated muscle contraction involved in embryonic body morphogenesis. Located in presynaptic active zone. Expressed in muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Brugada syndrome 4; episodic ataxia type 5; and intrinsic cardiomyopathy (multiple). Is an ortholog of human CACNB4 (calcium voltage-gated channel auxiliary subunit beta 4). WB:WBGene00000369 ccf-1 Predicted to enable poly(A)-specific ribonuclease activity. Involved in nuclear-transcribed mRNA poly(A) tail shortening and oogenesis. Located in P granule and P-body. Part of CCR4-NOT complex. Expressed in germ line. Is an ortholog of human CNOT7 (CCR4-NOT transcription complex subunit 7). WB:WBGene00000370 ccg-1 Enriched in several structures, including GLR; coelomocyte; enteric muscle; germ line; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by thirteen chemicals including aldicarb; rotenone; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00000371 cox-5B Predicted to enable metal ion binding activity. Involved in determination of adult lifespan; lipid storage; and proton motive force-driven mitochondrial ATP synthesis. Predicted to be located in mitochondrial envelope. Predicted to be part of mitochondrial respiratory chain complex IV. Is an ortholog of human COX5B (cytochrome c oxidase subunit 5B). WB:WBGene00000372 cyp-13A7 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00000373 cyp-14A5 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Involved in response to gamma radiation. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and hereditary spastic paraplegia 56. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1). WB:WBGene00000374 cyp-31A1 Enriched in neurons; sensory neurons; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Lithium Chloride; lithium carbonate; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00000375 cyp-44A1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and lipid storage disease (multiple). Is an ortholog of human CYP24A1 (cytochrome P450 family 24 subfamily A member 1). WB:WBGene00000376 ccr-4 Predicted to enable poly(A)-specific ribonuclease activity. Involved in nuclear-transcribed mRNA poly(A) tail shortening. Located in cytoplasm. Part of CCR4-NOT complex. Expressed in body wall musculature; germ line; neurons; somatic cell; and in male. Is an ortholog of human CNOT6 (CCR4-NOT transcription complex subunit 6) and CNOT6L (CCR4-NOT transcription complex subunit 6 like). WB:WBGene00000377 cct-1 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Located in nucleus. Part of chaperonin-containing T-complex. Expressed in nerve ring and in male. Is an ortholog of human TCP1 (t-complex 1). WB:WBGene00000378 cct-2 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytosol. Predicted to be part of chaperonin-containing T-complex. Expressed in head; pharyngeal muscle cell; tail; and touch receptor neurons. Is an ortholog of human CCT2 (chaperonin containing TCP1 subunit 2). WB:WBGene00000379 cct-4 Predicted to enable unfolded protein binding activity. Involved in post-embryonic body morphogenesis. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Expressed in head; tail; and touch receptor neurons. Is an ortholog of human CCT4 (chaperonin containing TCP1 subunit 4). WB:WBGene00000380 cct-5 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Part of chaperonin-containing T-complex. Is an ortholog of human CCT5 (chaperonin containing TCP1 subunit 5). WB:WBGene00000381 cct-6 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Is an ortholog of human CCT6B (chaperonin containing TCP1 subunit 6B). WB:WBGene00000382 cdc-6 Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in mitotic DNA replication checkpoint signaling. Located in condensed nuclear chromosome; cytoplasm; and nucleolus. Expressed in seam cell. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 5. Is an ortholog of human CDC6 (cell division cycle 6). WB:WBGene00000383 cdc-14 Enables phosphoprotein phosphatase activity. Involved in several processes, including cytoskeleton-dependent cytokinesis; mitotic spindle midzone assembly; and regulation of cell cycle process. Located in microtubule cytoskeleton; midbody; and nucleolus. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 32 and renal cell carcinoma. Is an ortholog of human CDC14A (cell division cycle 14A). WB:WBGene00000384 cdc-16 No description available WB:WBGene00000386 cdc-25.1 Predicted to enable protein tyrosine phosphatase activity. Involved in meiotic spindle organization and positive regulation of mitotic cell cycle. Located in nucleus. Expressed in several structures, including Z2; Z3; germ line; oocyte; and sperm. WB:WBGene00000387 cdc-25.2 Predicted to enable protein tyrosine phosphatase activity. Involved in epidermal cell division. Acts upstream of or within nematode male tail tip morphogenesis. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including diagonal muscle; germ line; hypodermis; oocyte; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive polycystic kidney disease; endometrial hyperplasia; and reproductive organ cancer (multiple). Is an ortholog of human CDC25B (cell division cycle 25B). WB:WBGene00000388 cdc-25.3 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in G2/M transition of mitotic cell cycle; positive regulation of G2/M transition of mitotic cell cycle; and positive regulation of G2/MI transition of meiotic cell cycle. Located in nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive polycystic kidney disease; endometrial hyperplasia; and reproductive organ cancer (multiple). Is an ortholog of human CDC25A (cell division cycle 25A); CDC25B (cell division cycle 25B); and CDC25C (cell division cycle 25C). WB:WBGene00000389 cdc-25.4 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in G2/M transition of mitotic cell cycle; positive regulation of G2/M transition of mitotic cell cycle; and positive regulation of G2/MI transition of meiotic cell cycle. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including ganglia; germ line; male-specific anatomical entity; pharyngeal cell; and ventral nerve cord. WB:WBGene00000390 cdc-42 Enables GTP binding activity and GTPase activity. Involved in several processes, including establishment of mitotic spindle orientation; positive regulation of nematode male tail tip morphogenesis; and regulation of cellular component organization. Located in centrosome; cytoplasm; and plasma membrane. Expressed in several structures, including AIY; P8.pa; hermaphrodite gonad; hypodermal cell; and nerve ring. Used to study cerebral cavernous malformation. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; bipolar disorder; fibrosarcoma; and rhinitis. Is an ortholog of human CDC42 (cell division cycle 42). WB:WBGene00000391 cdd-1 Enables RNA binding activity and deoxycytidine deaminase activity. Involved in RNA modification; deoxycytidine catabolic process; and uridine biosynthetic process. Predicted to be located in cytosol. Expressed in intestine; pharynx; and tail. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and stomach cancer. Is an ortholog of human CDA (cytidine deaminase). WB:WBGene00000392 cdd-2 Enables RNA binding activity; cytidine deaminase activity; and deoxycytidine deaminase activity. Involved in RNA modification; embryo development; and pyrimidine nucleoside metabolic process. Predicted to be located in cytosol. Expressed in intestine. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and stomach cancer. Is an ortholog of human CDA (cytidine deaminase). WB:WBGene00000393 cdf-1 Enables protein kinase binding activity. Involved in cellular response to zinc ion; positive regulation of Ras protein signal transduction; and positive regulation of vulval development. Located in basolateral plasma membrane. Expressed in several structures, including P5.ppp; P7.paa; rectal valve cell; vulval cell; and vulval muscle. Human ortholog(s) of this gene implicated in hypermanganesemia with dystonia 1. Is an ortholog of human SLC30A1 (solute carrier family 30 member 1). WB:WBGene00000395 cdh-3 Predicted to enable structural molecule activity. Involved in basement membrane disassembly and nematode male tail tip morphogenesis. Located in basement membrane; cytoplasm; and plasma membrane. Expressed in several structures, including HSN; VC neuron; anchor cell; epithelial cell; and ventral nerve cord. WB:WBGene00000396 cdh-4 Predicted to enable calcium ion binding activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Expressed in several structures, including QL; QR; VD neuron; non-striated muscle; and rectal gland cell. Human ortholog(s) of this gene implicated in carcinoma (multiple); colorectal cancer; and spinocerebellar ataxia 45. Is an ortholog of human FAT1 (FAT atypical cadherin 1); FAT2 (FAT atypical cadherin 2); and FAT3 (FAT atypical cadherin 3). WB:WBGene00000397 cdh-5 Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Usher syndrome type 1D; Usher syndrome type 1F; and autosomal recessive nonsyndromic deafness 23. Is an ortholog of human PCDH15 (protocadherin related 15). WB:WBGene00000399 cdh-7 Predicted to enable calcium ion binding activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in plasma membrane. WB:WBGene00000401 cdh-9 Predicted to enable calcium ion binding activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Is an ortholog of several human genes including PCDH1 (protocadherin 1); PCDH7 (protocadherin 7); and PCDH9 (protocadherin 9). WB:WBGene00000402 cdh-10 Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to be located in membrane. Expressed in K cell; K' cell; mc1; mc2; and seam cell. WB:WBGene00000403 casy-1 Predicted to enable several functions, including X11-like protein binding activity; amyloid-beta binding activity; and kinesin binding activity. Involved in several processes, including GABAergic synaptic transmission; olfactory learning; and positive regulation of synaptic vesicle transport. Located in several cellular components, including extracellular region; neuromuscular junction; and neuronal cell body membrane. Expressed in neurons. Is an ortholog of human CLSTN2 (calsyntenin 2) and CLSTN3 (calsyntenin 3). WB:WBGene00000405 cdk-1 Enables cyclin-dependent protein serine/threonine kinase activity and protein kinase binding activity. Involved in several processes, including positive regulation of meiotic nuclear division; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and sexual reproduction. Acts upstream of or within nematode male tail tip morphogenesis. Located in cytoplasm and nucleus. Expressed in embryonic cell and germ cell. Human ortholog(s) of this gene implicated in several diseases, including cervical cancer; hepatobiliary system cancer (multiple); and transitional cell carcinoma. Is an ortholog of human CDK1 (cyclin dependent kinase 1). WB:WBGene00000406 cdk-4 Enables protein serine/threonine kinase activity. Involved in nematode larval development; positive regulation of cell cycle process; and reproductive process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Expressed in gonad; intestine; neurons; and vulva. Used to study cancer. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); central nervous system cancer (multiple); and urinary system cancer (multiple). Is an ortholog of human CDK4 (cyclin dependent kinase 4) and CDK6 (cyclin dependent kinase 6). WB:WBGene00000407 cdk-5 Enables protein kinase activity. Involved in several processes, including GABAergic synaptic transmission; regulation of cellular localization; and regulation of synapse organization. Located in axon and synapse. Used to study epilepsy and lissencephaly. Human ortholog(s) of this gene implicated in Alzheimer's disease and lissencephaly 7 with cerebellar hypoplasia. Is an ortholog of human CDK5 (cyclin dependent kinase 5). WB:WBGene00000408 cdk-7 Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Involved in mRNA transcription and mitotic cell cycle, embryonic. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription factor TFIIK complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human CDK7 (cyclin dependent kinase 7). WB:WBGene00000409 cdk-8 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in G1/S transition of mitotic cell cycle. Predicted to be located in nucleus. Expressed in anchor cell and neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 87 and dilated cardiomyopathy. Is an ortholog of human CDK19 (cyclin dependent kinase 19) and CDK8 (cyclin dependent kinase 8). WB:WBGene00000410 cdk-9 Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Involved in embryo development; germ cell development; and nematode larval development. Part of euchromatin. Expressed in several structures, including germ line. Human ortholog(s) of this gene implicated in congestive heart failure. Is an ortholog of human CDK9 (cyclin dependent kinase 9). WB:WBGene00000411 cdl-1 Enables mRNA 3'-UTR binding activity. Involved in apoptotic process; embryo development; and mitotic chromosome condensation. Predicted to be located in cytoplasm. Predicted to be part of histone pre-mRNA 3'end processing complex. Expressed widely. Is an ortholog of human SLBP (stem-loop histone mRNA binding protein). WB:WBGene00000412 cdr-1 Involved in stress response to cadmium ion. Located in lysosome. Expressed in intestinal cell and intestine. WB:WBGene00000413 cdt-1 Predicted to enable DNA binding activity and DNA polymerase binding activity. Involved in positive regulation of nematode male tail tip morphogenesis. Located in cytoplasm and nucleus. Part of chromatin. Expressed in anchor cell; germ line; uterine epithelial cell; and vulD. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Is an ortholog of human CDT1 (chromatin licensing and DNA replication factor 1). WB:WBGene00000414 cec-1 Predicted to enable chromatin binding activity and methylated histone binding activity. Predicted to be involved in chromatin organization and negative regulation of transcription by RNA polymerase II. Predicted to be located in chromosome and nucleus. Predicted to be part of pericentric heterochromatin. Expressed in several structures, including germ line; oocyte; and somatic cell. WB:WBGene00000415 ced-1 Enables scavenger receptor activity. Involved in several processes, including cytoskeleton organization; left/right axis specification; and phagocytosis. Located in several cellular components, including phagocytic cup; phagocytic vesicle membrane; and pseudopodium membrane. Expressed in body wall musculature; engulfing cell; hyp7 syncytium; and muscle cell. Human ortholog(s) of this gene implicated in congenital myopathy 10B and early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome. Is an ortholog of human MEGF10 (multiple EGF like domains 10) and MEGF11 (multiple EGF like domains 11). WB:WBGene00000416 ced-2 Predicted to enable obsolete SH3/SH2 adaptor activity; receptor tyrosine kinase binding activity; and signaling adaptor activity. Involved in several processes, including engulfment of apoptotic cell; positive regulation of distal tip cell migration; and positive regulation of engulfment of apoptotic cell. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); chronic myeloid leukemia; and invasive ductal carcinoma. Is an ortholog of human CRK (CRK proto-oncogene, adaptor protein) and CRKL (CRK like proto-oncogene, adaptor protein). WB:WBGene00000417 ced-3 Enables cysteine-type endopeptidase activator activity involved in apoptotic process; cysteine-type endopeptidase activity involved in execution phase of apoptosis; and identical protein binding activity. Involved in several processes, including apoptotic process; protein metabolic process; and regulation of developmental process. Located in several cellular components, including neuronal cell body; perinuclear region of cytoplasm; and presynapse. Part of caspase complex. Expressed in several structures, including ABaraapapaa; NSM; apoptotic cell; germ line; and oocyte. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); gastrointestinal system cancer (multiple); and prostate disease (multiple). Is an ortholog of human CASP3 (caspase 3); CASP6 (caspase 6); and CASP7 (caspase 7). WB:WBGene00000418 ced-4 Enables several functions, including BH domain binding activity; ion binding activity; and peptidase activator activity. Involved in several processes, including muscle cell cellular homeostasis; positive regulation of synapse pruning; and regulation of apoptotic process. Located in several cellular components, including cytoplasm; membrane; and nucleus. Part of caspase complex. Expressed in several structures, including germ line. Human ortholog(s) of this gene implicated in Parkinson's disease; lung non-small cell carcinoma; and pancreatic cancer. Is an ortholog of human APAF1 (apoptotic peptidase activating factor 1). WB:WBGene00000419 ced-5 Enables SH3 domain binding activity and enzyme binding activity. Involved in several processes, including left/right axis specification; positive regulation of distal tip cell migration; and vesicle-mediated transport. Located in presynapse. Part of guanyl-nucleotide exchange factor complex. Expressed in body wall muscle cell; hermaphrodite somatic gonadal cell; and intestinal cell. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and immunodeficiency 40. Is an ortholog of human DOCK2 (dedicator of cytokinesis 2) and DOCK5 (dedicator of cytokinesis 5). WB:WBGene00000420 ced-6 Enables clathrin adaptor activity and scavenger receptor binding activity. Involved in several processes, including engulfment of apoptotic cell; left/right axis specification; and positive regulation of distal tip cell migration. Located in cytoplasmic side of plasma membrane and phagocytic vesicle. Is an ortholog of human GULP1 (GULP PTB domain containing engulfment adaptor 1). WB:WBGene00000421 ced-7 Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and lipid transporter activity. Involved in several processes, including establishment of localization; left/right axis specification; and positive regulation of distal tip cell migration. Located in plasma membrane. Expressed in Z2; Z3; germ line; neuronal sheath cell; and pharyngeal-intestinal valve. WB:WBGene00000422 ced-8 Enables phospholipid scramblase activity. Involved in apoptotic process; embryo development; and engulfment of apoptotic cell. Located in plasma membrane. Is an ortholog of human XKR6 (XK related 6). WB:WBGene00000423 ced-9 Enables GTPase activator activity and protein sequestering activity. Involved in several processes, including cellular component disassembly; positive regulation of reproductive process; and regulation of cellular component organization. Located in several cellular components, including mitochondrial outer membrane; neuronal cell body; and perinuclear region of cytoplasm. Expressed in several structures, including gonad. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; B-cell lymphoma (multiple); colorectal adenocarcinoma; and transient cerebral ischemia. Is an ortholog of human BCL2L2 (BCL2 like 2) and BCL2L2-PABPN1 (BCL2L2-PABPN1 readthrough). WB:WBGene00000424 ced-10 Enables GTP binding activity and GTPase activity. Involved in several processes, including axon development; establishment or maintenance of cell polarity; and regulation of cellular component organization. Located in cytoplasmic side of plasma membrane; cytoplasmic vesicle; and neuronal cell body. Expressed in several structures, including CAN; GABAergic neurons; distal tip cell; intestine; and somatic nervous system. Used to study epilepsy. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant intellectual developmental disorder 48; combined immunodeficiency (multiple); and gastrointestinal system cancer (multiple). Is an ortholog of human RAC1 (Rac family small GTPase 1). WB:WBGene00000425 ced-11 Predicted to enable monoatomic cation channel activity. Involved in apoptotic process. Predicted to be located in membrane. Expressed in apoptotic cell; head; hypodermis; and tail. WB:WBGene00000426 ced-12 Enables phosphatidylinositol phosphate binding activity; proline-rich region binding activity; and small GTPase binding activity. Involved in several processes, including cytoskeleton organization; engulfment of apoptotic cell; and left/right axis specification. Located in cytoplasm and plasma membrane. Part of guanyl-nucleotide exchange factor complex. Expressed in intestinal cell and tail. Is an ortholog of human ELMO1 (engulfment and cell motility 1); ELMO2 (engulfment and cell motility 2); and ELMO3 (engulfment and cell motility 3). WB:WBGene00000427 ced-13 Enables BH domain binding activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and positive regulation of apoptotic process. WB:WBGene00000428 ceh-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in DVC; lateral ganglion; and seam cell. Is an ortholog of human NKX1-1 (NK1 homeobox 1) and NKX1-2 (NK1 homeobox 2). WB:WBGene00000429 ceh-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in brain development; neuron differentiation; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in neurons; pharynx; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in carcinoma (multiple) and stomach cancer. Is an ortholog of human EMX1 (empty spiracles homeobox 1). WB:WBGene00000430 ceh-5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in brain development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including coelomocyte; head muscle; somatic nervous system; tail; and terminal bulb. Human ortholog(s) of this gene implicated in syndromic microphthalmia 11. Is an ortholog of human VAX1 (ventral anterior homeobox 1). WB:WBGene00000431 ceh-6 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in transdifferentiation. Acts upstream of with a positive effect on multicellular organismal-level water homeostasis. Located in cytosol and nucleus. Expressed in body wall musculature; hyp7 syncytium; intestine; and neurons. Human ortholog(s) of this gene implicated in X-linked deafness 2. Is an ortholog of human POU3F1 (POU class 3 homeobox 1); POU3F3 (POU class 3 homeobox 3); and POU3F4 (POU class 3 homeobox 4). WB:WBGene00000432 ceh-7 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in I3 neuron; head neurons; and in male. WB:WBGene00000433 ceh-8 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in lateral ganglion and somatic gonad precursor. Human ortholog(s) of this gene implicated in isolated microphthalmia 3 and retinal degeneration (multiple). Is an ortholog of human RAX2 (retina and anterior neural fold homeobox 2). WB:WBGene00000434 ceh-9 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head muscle; head neurons; intestine; lumbar neurons; and somatic nervous system. WB:WBGene00000435 ceh-10 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; generation of neurons; and regulation of cell migration. Located in nucleus. Expressed in ABalapppaa; CAN; head neurons; seam cell; and somatic nervous system. Human ortholog(s) of this gene implicated in eye disease (multiple). Is an ortholog of human VSX2 (visual system homeobox 2). WB:WBGene00000436 ceh-12 Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in central nervous system development and neuron projection morphogenesis. Predicted to be located in nucleus. Expressed in VB neuron; ventral nerve cord; and vulval muscle. Human ortholog(s) of this gene implicated in Currarino syndrome. Is an ortholog of human MNX1 (motor neuron and pancreas homeobox 1). WB:WBGene00000437 ceh-13 Predicted to enable DNA-binding transcription factor activity. Involved in cell-cell adhesion and embryo development. Located in cytoplasm and nucleus. Expressed in several structures, including embryonic cell; hypodermis; neurons; non-striated muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in Athabaskan brainstem dysgenesis syndrome and autistic disorder. Is an ortholog of human HOXB1 (homeobox B1) and HOXD1 (homeobox D1). WB:WBGene00000438 ceh-14 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in neuron development; positive regulation of transcription by RNA polymerase II; and thermosensory behavior. Located in nucleus. Expressed in several structures, including hypodermal cell; neurons; somatic nervous system; spermatheca; and tail. Human ortholog(s) of this gene implicated in panhypopituitarism. Is an ortholog of human LHX3 (LIM homeobox 3). WB:WBGene00000439 ceh-16 Enables sequence-specific DNA binding activity. Involved in several processes, including embryonic body morphogenesis; epidermal cell fate specification; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including ABarpa; AIZ; hyp5; retrovesicular ganglion neurons; and seam cell. Human ortholog(s) of this gene implicated in Parkinson's disease and autistic disorder. Is an ortholog of human EN1 (engrailed homeobox 1) and EN2 (engrailed homeobox 2). WB:WBGene00000440 ceh-17 Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in axon guidance; positive regulation of transcription by RNA polymerase II; and regulation of axon extension. Located in nucleus. Expressed in DA8; head muscle; head neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including congenital central hypoventilation syndrome; congenital fibrosis of the extraocular muscles 2; and neuroblastoma. Is an ortholog of human PHOX2A (paired like homeobox 2A). WB:WBGene00000441 ceh-18 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; gamete generation; and negative regulation of oocyte maturation. Located in nucleus. Expressed in body wall musculature; gonad; neurons; non-striated muscle; and somatic nervous system. Is an ortholog of human POU2F2 (POU class 2 homeobox 2) and POU2F3 (POU class 2 homeobox 3). WB:WBGene00000442 ceh-19 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in neurons. WB:WBGene00000443 ceh-20 Enables cis-regulatory region sequence-specific DNA binding activity and transcription coactivator binding activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell differentiation; positive regulation of mesodermal cell fate specification; and regulation of asymmetric cell division. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including P1.p; P2.p; neurons; seam cell; and somatic nervous system. Human ortholog(s) of this gene implicated in congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay; esophagus squamous cell carcinoma; and glaucoma. Is an ortholog of human PBX4 (PBX homeobox 4). WB:WBGene00000444 ceh-21 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed widely. WB:WBGene00000445 ceh-22 Enables sequence-specific DNA binding activity. Involved in several processes, including gonad morphogenesis; pharyngeal muscle development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including G1; gonad; neurons; pharyngeal cell; and ventral nerve cord. Used to study cancer. Is an ortholog of human NKX2-2 (NK2 homeobox 2). WB:WBGene00000446 ceh-23 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in determination of adult lifespan and positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation. Located in nucleus. Expressed in intestine; nervous system; and tail. WB:WBGene00000447 ceh-24 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation; regulation of transcription by RNA polymerase II; and regulation of transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Expressed in head muscle; intestine; neurons; non-striated muscle; and ventral nerve cord. Human ortholog(s) of this gene implicated in choreatic disease and thyroid gland papillary carcinoma. Is an ortholog of human NKX2-1 (NK2 homeobox 1) and NKX2-4 (NK2 homeobox 4). WB:WBGene00000448 pros-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in glial cell development. Located in nucleus. Expressed in several structures, including labial sensillum and neuronal sheath cell. Is an ortholog of human PROX1 (prospero homeobox 1). WB:WBGene00000449 ceh-27 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in I6 neuron; intestine; nerve ring; and nerve ring neurons. WB:WBGene00000450 ceh-28 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and regulation of neuron differentiation. Part of chromatin. Expressed in several structures, including ABalaappa; ABalaappaa; ABalaappap; ABalapapa; and M4 neuron. Human ortholog(s) of this gene implicated in several diseases, including aortic valve disease 2; congenital heart disease (multiple); and heart conduction disease (multiple). Is an ortholog of human NKX2-5 (NK2 homeobox 5). WB:WBGene00000451 ceh-30 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of apoptotic process; nervous system development; and sex differentiation. Located in nucleus. Expressed in embryonic cell and neurons. Human ortholog(s) of this gene implicated in colorectal cancer; oral squamous cell carcinoma; and stomach cancer. Is an ortholog of human BARHL2 (BarH like homeobox 2). WB:WBGene00000452 ceh-31 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in AVB; head neurons; nerve ring neurons; and pharynx. Human ortholog(s) of this gene implicated in Alzheimer's disease; high grade glioma; and triple-receptor negative breast cancer. Is an ortholog of human BARHL1 (BarH like homeobox 1). WB:WBGene00000453 ceh-32 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in post-embryonic animal morphogenesis. Located in nucleus. Expressed in several structures, including anterior hypodermis; gonadal sheath cell; head ganglion; pharyngeal neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including holoprosencephaly 2; optic disc anomalies with retinal and/or macular dystrophy; and renal Wilms' tumor. Is an ortholog of human SIX3 (SIX homeobox 3) and SIX6 (SIX homeobox 6). WB:WBGene00000454 ceh-33 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Expressed in head and head muscle. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant nonsyndromic deafness 23; carcinoma (multiple); and optic disc anomalies with retinal and/or macular dystrophy. Is an ortholog of human SIX1 (SIX homeobox 1); SIX2 (SIX homeobox 2); and SIX6 (SIX homeobox 6). WB:WBGene00000455 ceh-34 Enables sequence-specific DNA binding activity. Involved in mesodermal cell fate specification; positive regulation of apoptotic process involved in development; and regulation of DNA-templated transcription. Located in nucleus. Expressed in body wall musculature; corpus; head; male sex myoblast; and pharyngeal neurons. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant nonsyndromic deafness 23; carcinoma (multiple); and renal Wilms' tumor. Is an ortholog of human SIX1 (SIX homeobox 1) and SIX2 (SIX homeobox 2). WB:WBGene00000457 ceh-36 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in neuron fate specification; positive regulation of transcription by RNA polymerase II; and sensory perception of chemical stimulus. Located in nucleus. Expressed in ABaraappa; ABaraappaa; amphid neurons; and head neurons. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 5. Is an ortholog of human ARGFX (arginine-fifty homeobox); DPRX (divergent-paired related homeobox); and NOBOX (NOBOX oogenesis homeobox). WB:WBGene00000458 ceh-37 Enables DNA binding activity, bending and double-stranded telomeric DNA binding activity. Involved in neuron fate specification; olfactory behavior; and regulation of transcription by RNA polymerase II. Located in chromosome, telomeric region. Expressed in several structures, including ABarpaap; dorsal nerve cord; excretory cell; head muscle; and head neurons. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 7 and cone-rod dystrophy 2. Is an ortholog of human CRX (cone-rod homeobox). WB:WBGene00000459 ceh-38 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including body wall musculature; excretory cell; intestine; neurons; and somatic nervous system. WB:WBGene00000460 ceh-39 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and primary sex determination. Located in condensed nuclear chromosome and germ cell nucleus. Expressed in body wall musculature; germ line; gonad; neurons; and ventral nerve cord. WB:WBGene00000461 ceh-40 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in animal organ development; neuron development; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in dopaminergic neurons. WB:WBGene00000462 ceh-41 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in body wall musculature; neurons; and somatic nervous system. WB:WBGene00000463 ceh-43 Enables DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Involved in dopaminergic neuron differentiation and embryo development. Predicted to be located in nucleus. Expressed in several structures, including ABarpa; anterior hypodermis; neuronal sheath cell; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including amelogenesis imperfecta type 4; orofacial cleft 15; and split hand-foot malformation (multiple). Is an ortholog of human DLX1 (distal-less homeobox 1). WB:WBGene00000464 ceh-44 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head muscle; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including developmental and epileptic encephalopathy 67; gastrointestinal system cancer (multiple); and insulinoma. Is an ortholog of human CUX2 (cut like homeobox 2). WB:WBGene00000465 cpg-1 Enables chitin binding activity. Involved in several processes, including eggshell formation; mitotic cytokinesis; and regulation of cytokinesis. Located in external encapsulating structure. Expressed in eggshell; germ line; and oocyte. WB:WBGene00000466 cel-1 Enables polynucleotide 5'-phosphatase activity. Involved in polynucleotide 5' dephosphorylation and positive regulation of gene expression. Located in nucleus. Expressed in tail. Is an ortholog of human RNGTT (RNA guanylyltransferase and 5'-phosphatase). WB:WBGene00000467 cep-1 Enables several functions, including DNA-binding transcription factor activity; protein homodimerization activity; and zinc ion binding activity. Involved in several processes, including determination of adult lifespan; intracellular signal transduction; and positive regulation of transcription by RNA polymerase II. Located in germ cell nucleus; nucleolus; and nucleoplasm. Expressed in Z2; Z3; germ line; pharyngeal cell; and pharynx. Used to study cancer. WB:WBGene00000468 ces-1 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of programmed cell death and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human SCRT1 (scratch family transcriptional repressor 1) and SCRT2 (scratch family transcriptional repressor 2). WB:WBGene00000469 ces-2 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; identical protein binding activity; and protein heterodimerization activity. Involved in several processes, including apoptotic process; positive regulation of programmed cell death; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in excretory duct cell. Used to study acute lymphoblastic leukemia. Human ortholog(s) of this gene implicated in osteoporosis and stomach cancer. Is an ortholog of human DBP (D-box binding PAR bZIP transcription factor); HLF (HLF transcription factor, PAR bZIP family member); and TEF (TEF transcription factor, PAR bZIP family member). WB:WBGene00000470 ces-3 No description available WB:WBGene00000471 ces-4 No description available WB:WBGene00000472 cey-1 Predicted to enable nucleic acid binding activity. Predicted to be involved in regulation of gene expression. Located in endoplasmic reticulum. Expressed in germ cell; germ line; pharynx; and somatic cell. Is an ortholog of human YBX3 (Y-box binding protein 3). WB:WBGene00000473 cey-2 Predicted to enable nucleic acid binding activity. Predicted to be involved in regulation of gene expression. Part of ribonucleoprotein complex. Expressed in germ cell; germ line; pharynx; and somatic cell. Used to study Huntington's disease. Is an ortholog of human YBX2 (Y-box binding protein 2). WB:WBGene00000474 cey-3 Enables ribonucleoprotein complex binding activity. Predicted to be involved in regulation of gene expression. Part of ribonucleoprotein complex. Expressed in germ cell; head muscle; intestine; somatic cell; and somatic nervous system. Used to study Huntington's disease. WB:WBGene00000475 cey-4 Enables ribonucleoprotein complex binding activity. Predicted to be involved in regulation of gene expression. Part of ribonucleoprotein complex. Expressed in germ cell; germ line; and somatic cell. Is an ortholog of human YBX1 (Y-box binding protein 1) and YBX2 (Y-box binding protein 2). WB:WBGene00000476 cfi-1 Enables sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; neuron fate specification; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in ganglia; head muscle; neurons; and pharyngeal muscle cell. Is an ortholog of human ARID3B (AT-rich interaction domain 3B). WB:WBGene00000477 cft-1 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in excretory canal. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; alcoholic pancreatitis; bronchial disease (multiple); and lung disease (multiple). Is an ortholog of human CFTR (CF transmembrane conductance regulator). WB:WBGene00000478 cfz-2 Predicted to enable Wnt receptor activity and Wnt-protein binding activity. Involved in neuroblast migration; neuron migration; and positive regulation of motor neuron migration. Predicted to be located in plasma membrane. Expressed in intestine; nervous system; and pharynx. Is an ortholog of human FZD5 (frizzled class receptor 5). WB:WBGene00000479 cgh-1 Predicted to enable RNA helicase activity and mRNA binding activity. Involved in several processes, including P-body assembly; determination of adult lifespan; and negative regulation of translation. Located in P granule; P-body; and cytoplasmic stress granule. Part of messenger ribonucleoprotein complex. Expressed in several structures, including Z2; Z3; germ line; gonad; and neurons. Is an ortholog of human DDX6 (DEAD-box helicase 6). WB:WBGene00000480 cgp-1 Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Is an ortholog of human GTPBP1 (GTP binding protein 1). WB:WBGene00000481 cha-1 Enables choline O-acetyltransferase activity. Involved in acetylcholine biosynthetic process. Located in several cellular components, including cytosol; excitatory synapse; and neuronal cell body. Expressed in IL2 neuron. Human ortholog(s) of this gene implicated in Alzheimer's disease and congenital myasthenic syndrome 6. Is an ortholog of human CHAT (choline O-acetyltransferase). WB:WBGene00000482 chd-3 Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent activity, acting on DNA; and chromatin binding activity. Involved in cell fate determination; negative regulation of Ras protein signal transduction; and negative regulation of vulval development. Predicted to be located in nucleus. Predicted to be part of NuRD complex. Expressed in several structures, including distal tip cell; pharynx; ventral nerve cord; vulva; and vulval precursor cell. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung adenocarcinoma; and lymphoma. Is an ortholog of human CHD3 (chromodomain helicase DNA binding protein 3). WB:WBGene00000483 che-1 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including response to alkaline pH; response to metal ion; and response to methionine. Predicted to be located in nucleus. Expressed in ASEL and ASER. WB:WBGene00000484 che-2 Involved in several processes, including dauer larval development; negative regulation of transforming growth factor beta receptor signaling pathway; and positive regulation of locomotion involved in locomotory behavior. Located in ciliary basal body and non-motile cilium. Expressed in neurons. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 2. Is an ortholog of human IFT80 (intraflagellar transport 80). WB:WBGene00000485 che-3 Predicted to enable dynein light intermediate chain binding activity and minus-end-directed microtubule motor activity. Involved in several processes, including dauer entry; non-motile cilium assembly; and positive regulation of dauer larval development. Located in non-motile cilium. Expressed in I4 neuron; PDEL; PDER; and nerve ring. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 3. Is an ortholog of human DYNC2H1 (dynein cytoplasmic 2 heavy chain 1). WB:WBGene00000487 che-6 Predicted to enable cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Located in neuronal cell body. Expressed in ASEL; ASER; AWCL; and AWCR. Human ortholog(s) of this gene implicated in achromatopsia 2 and retinitis pigmentosa 49. Is an ortholog of several human genes including CNGA1 (cyclic nucleotide gated channel subunit alpha 1); CNGA2 (cyclic nucleotide gated channel subunit alpha 2); and CNGA3 (cyclic nucleotide gated channel subunit alpha 3). WB:WBGene00000488 che-7 Predicted to enable gap junction channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in gap junction and plasma membrane. Expressed in nervous system and tail neurons. WB:WBGene00000490 che-11 Involved in several processes, including dauer entry; determination of adult lifespan; and positive regulation of intracellular transport. Located in non-motile cilium. Expressed in head and neurons. Human ortholog(s) of this gene implicated in retinitis pigmentosa and short-rib thoracic dysplasia 9 with or without polydactyly. Is an ortholog of human IFT140 (intraflagellar transport 140). WB:WBGene00000491 che-12 Predicted to enable microtubule binding activity. Involved in several processes, including cilium assembly; hyperosmotic response; and sensory perception. Located in cilium; dendrite; and neuronal cell body. Expressed in amphid neurons and phasmid neurons. Used to study ciliopathy. Human ortholog(s) of this gene implicated in Joubert syndrome. Is an ortholog of human TOGARAM1 (TOG array regulator of axonemal microtubules 1) and TOGARAM2 (TOG array regulator of axonemal microtubules 2). WB:WBGene00000492 che-13 Involved in chemosensory behavior; cilium organization; and protein localization. Located in axoneme; ciliary basal body; and ciliary transition zone. Part of intraciliary transport particle B. Expressed in neurons. Used to study ciliopathy. Human ortholog(s) of this gene implicated in orofaciodigital syndrome. Is an ortholog of human IFT57 (intraflagellar transport 57). WB:WBGene00000493 che-14 Predicted to enable transmembrane transporter activity. Predicted to be involved in smoothened signaling pathway. Located in apical plasma membrane. Expressed in epithelial cell; excretory system; hypodermis; rectum; and vulva. Is an ortholog of human DISP1 (dispatched RND transporter family member 1) and DISP2 (dispatched RND transporter family member 2). WB:WBGene00000494 che-15 No description available WB:WBGene00000495 che-16 No description available WB:WBGene00000496 chs-1 Predicted to enable chitin synthase activity. Involved in cell wall chitin biosynthetic process; eggshell formation; and positive regulation of protein localization to cell cortex. Located in cell cortex and plasma membrane. Expressed in Psub1. WB:WBGene00000497 chs-2 Predicted to enable chitin synthase activity. Involved in chitin biosynthetic process and positive regulation of nematode larval development. Predicted to be located in cell periphery and cell septum. Expressed in pharynx. WB:WBGene00000498 chk-1 Predicted to enable protein serine/threonine kinase activity. Involved in embryo development and mitotic DNA replication checkpoint signaling. Predicted to be located in nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CHEK1 (checkpoint kinase 1). WB:WBGene00000499 chk-2 Predicted to enable protein serine/threonine kinase activity. Involved in positive regulation of histone H3-K9 methylation. Predicted to be located in cytoplasm and nucleus. Expressed in germline blastomere. Human ortholog(s) of this gene implicated in several diseases, including Li-Fraumeni syndrome 2; breast cancer (multiple); and germ cell cancer (multiple). Is an ortholog of human CHEK2 (checkpoint kinase 2). WB:WBGene00000500 chn-1 Enables Hsp70 protein binding activity; ubiquitin protein ligase binding activity; and ubiquitin-ubiquitin ligase activity. Involved in several processes, including determination of adult lifespan; egg-laying behavior; and protein ubiquitination. Located in cytoplasm. Expressed in several structures, including copulatory spicule; germ line; hermaphrodite distal tip cell; intestine; and pharynx. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 16 and cerebellar ataxia type 48. Is an ortholog of human STUB1 (STIP1 homology and U-box containing protein 1). WB:WBGene00000501 cho-1 Enables choline transmembrane transporter activity. Involved in choline transport. Located in axon; neuronal cell body; and synaptic vesicle. Expressed in head mesodermal cell; intestine; nerve ring; and neurons. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 20; distal hereditary motor neuronopathy type 7A; and major depressive disorder. Is an ortholog of human SLC5A7 (solute carrier family 5 member 7). WB:WBGene00000502 chp-1 Predicted to enable zinc ion binding activity. Predicted to be involved in centrosome duplication. Is an ortholog of human CHORDC1 (cysteine and histidine rich domain containing 1) and ITGB1BP2 (integrin subunit beta 1 binding protein 2). WB:WBGene00000503 cht-1 Enables chitinase activity. Involved in chitin catabolic process and response to fungus. Predicted to be located in extracellular region. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Is an ortholog of human CHIA (chitinase acidic). WB:WBGene00000504 cib-1 Acts upstream of or within cell fate specification and embryo development. WB:WBGene00000505 cib-3 No description available WB:WBGene00000506 cic-1 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Expressed in neurons. Is an ortholog of human CCNC (cyclin C). WB:WBGene00000507 cit-1.1 Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of DNA-templated transcription, elongation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of cyclin/CDK positive transcription elongation factor complex. Expressed widely. Is an ortholog of human CCNT1 (cyclin T1). WB:WBGene00000508 cit-1.2 Enables cyclin-dependent protein serine/threonine kinase activator activity. Involved in embryo development. Located in nucleus. Expressed in several structures, including head. Is an ortholog of human CCNT1 (cyclin T1). WB:WBGene00000509 cka-1 Enables choline kinase activity. Involved in CDP-choline pathway. Located in cell cortex. Human ortholog(s) of this gene implicated in several diseases, including colon adenoma; megaconial type congenital muscular dystrophy; narcolepsy; and recurrent hypersomnia. Is an ortholog of human CHKA (choline kinase alpha) and CHKB (choline kinase beta). WB:WBGene00000510 cka-2 Enables choline kinase activity. Involved in CDP-choline pathway. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including colon adenoma; megaconial type congenital muscular dystrophy; narcolepsy; and recurrent hypersomnia. Is an ortholog of human CHKA (choline kinase alpha). WB:WBGene00000511 ckb-1 Predicted to enable choline kinase activity and ethanolamine kinase activity. Predicted to be involved in CDP-choline pathway and phosphatidylethanolamine biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including colon adenoma; megaconial type congenital muscular dystrophy; narcolepsy; and recurrent hypersomnia. Is an ortholog of human CHKA (choline kinase alpha) and CHKB (choline kinase beta). WB:WBGene00000512 ckb-2 Enables choline kinase activity. Involved in CDP-choline pathway and IRE1-mediated unfolded protein response. Predicted to be located in cytoplasm. Expressed in head and tail. Human ortholog(s) of this gene implicated in several diseases, including colon adenoma; megaconial type congenital muscular dystrophy; narcolepsy; and recurrent hypersomnia. Is an ortholog of human CHKA (choline kinase alpha) and CHKB (choline kinase beta). WB:WBGene00000513 ckb-3 Predicted to enable choline kinase activity and ethanolamine kinase activity. Predicted to be involved in CDP-choline pathway and phosphatidylethanolamine biosynthetic process. Predicted to be located in cytoplasm. Expressed in Z1; Z4; pm6; and somatic gonad. Human ortholog(s) of this gene implicated in several diseases, including colon adenoma; megaconial type congenital muscular dystrophy; narcolepsy; and recurrent hypersomnia. Is an ortholog of human CHKA (choline kinase alpha) and CHKB (choline kinase beta). WB:WBGene00000514 ckb-4 Enables choline kinase activity. Involved in CDP-choline pathway. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including colon adenoma; megaconial type congenital muscular dystrophy; narcolepsy; and recurrent hypersomnia. Is an ortholog of human CHKA (choline kinase alpha) and CHKB (choline kinase beta). WB:WBGene00000515 ckc-1 Predicted to enable ethanolamine kinase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be located in cytoplasm. Is an ortholog of human ETNK2 (ethanolamine kinase 2). WB:WBGene00000516 cki-1 Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity. Involved in several processes, including gonad development; regulation of cell cycle process; and regulation of cell division. Located in nucleus. Expressed in several structures, including excretory duct; hermaphrodite somatic gonadal cell; hypodermal cell; pharynx; and somatic gonad precursor. Human ortholog(s) of this gene implicated in several diseases, including hematologic cancer (multiple); lung carcinoma (multiple); and urinary system cancer (multiple). Is an ortholog of human CDKN1B (cyclin dependent kinase inhibitor 1B). WB:WBGene00000517 cki-2 Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity. Involved in gonad development; regulation of cell cycle process; and regulation of cell division. Predicted to be located in nucleus. Expressed in several structures, including P3.pa; P3.pp; P5.ppp; P7.paa; and germ line. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); and urinary system cancer (multiple). Is an ortholog of human CDKN1B (cyclin dependent kinase inhibitor 1B). WB:WBGene00000518 ckk-1 Enables calmodulin binding activity and calmodulin-dependent protein kinase activity. Predicted to be involved in CAMKK-AMPK signaling cascade. Located in cytoplasm and nucleus. Expressed in head neurons; tail neurons; and vulval muscle. Human ortholog(s) of this gene implicated in high grade glioma. Is an ortholog of human CAMKK1 (calcium/calmodulin dependent protein kinase kinase 1). WB:WBGene00000519 cku-70 Predicted to enable telomeric DNA binding activity. Predicted to contribute to double-stranded DNA binding activity. Involved in DNA repair. Predicted to be located in nucleus. Predicted to be part of Ku70:Ku80 complex. Human ortholog(s) of this gene implicated in basal cell carcinoma and squamous cell carcinoma. Is an ortholog of human XRCC6 (X-ray repair cross complementing 6). WB:WBGene00000520 cku-80 Predicted to enable telomeric DNA binding activity. Predicted to contribute to double-stranded DNA binding activity. Involved in DNA repair. Predicted to be located in nucleus. Predicted to be part of Ku70:Ku80 complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); chronic obstructive pulmonary disease; and multiple myeloma. Is an ortholog of human XRCC5 (X-ray repair cross complementing 5). WB:WBGene00000521 cky-1 Contributes to sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. Expressed in pharyngeal cell. Is an ortholog of human NPAS4 (neuronal PAS domain protein 4). WB:WBGene00000522 clc-1 Involved in defense response to Gram-positive bacterium; epithelial cell-cell adhesion; and innate immune response. Located in cell-cell junction. Expressed in pharynx. WB:WBGene00000523 clc-2 Involved in epithelial cell-cell adhesion. Located in plasma membrane. Expressed in hypodermis and seam cell. WB:WBGene00000524 clc-3 Predicted to be involved in epithelial cell-cell adhesion. Located in plasma membrane. WB:WBGene00000525 clc-4 Predicted to be involved in epithelial cell-cell adhesion. Predicted to be located in membrane. WB:WBGene00000526 clc-5 Predicted to be located in plasma membrane. WB:WBGene00000527 cle-1 Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in several processes, including cholinergic synaptic transmission; generation of neurons; and inductive cell migration. Located in basement membrane and cell junction. Expressed in several structures, including basal lamina; head mesodermal cell; neurons; smooth muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in primary angle-closure glaucoma. Is an ortholog of human COL15A1 (collagen type XV alpha 1 chain) and COL18A1 (collagen type XVIII alpha 1 chain). WB:WBGene00000528 clh-1 Predicted to enable voltage-gated chloride channel activity. Predicted to be involved in chloride transport. Predicted to be located in plasma membrane. Expressed in several structures, including amphid sensillum; anterior hypodermis; cephalic sheath cell; spermatheca; and vulval cell. Human ortholog(s) of this gene implicated in Thomsen disease; idiopathic generalized epilepsy 11; and primary hyperaldosteronism. Is an ortholog of human CLCN1 (chloride voltage-gated channel 1) and CLCN2 (chloride voltage-gated channel 2). WB:WBGene00000529 clh-2 Predicted to enable voltage-gated chloride channel activity. Predicted to be involved in chloride transport. Predicted to be located in plasma membrane. Expressed in several structures, including ganglia; intestine; pharyngeal-intestinal valve; somatic nervous system; and vulval muscle. Human ortholog(s) of this gene implicated in Thomsen disease; idiopathic generalized epilepsy 11; and primary hyperaldosteronism. Is an ortholog of human CLCN1 (chloride voltage-gated channel 1) and CLCN2 (chloride voltage-gated channel 2). WB:WBGene00000530 clh-3 Enables voltage-gated chloride channel activity. Involved in chloride transmembrane transport. Located in plasma membrane. Expressed in egg-laying apparatus; epithelial cell; excretory cell; intestine; and muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Thomsen disease; idiopathic generalized epilepsy 11; and renal tubular transport disease (multiple). Is an ortholog of human CLCN1 (chloride voltage-gated channel 1) and CLCN2 (chloride voltage-gated channel 2). WB:WBGene00000531 clh-4 Predicted to enable voltage-gated chloride channel activity. Predicted to be involved in chloride transport. Predicted to be located in plasma membrane. Expressed in excretory cell. Human ortholog(s) of this gene implicated in Thomsen disease; idiopathic generalized epilepsy 11; and primary hyperaldosteronism. Is an ortholog of human CLCN1 (chloride voltage-gated channel 1) and CLCN2 (chloride voltage-gated channel 2). WB:WBGene00000532 clh-5 Predicted to enable voltage-gated chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in Golgi apparatus; early endosome; and synaptic vesicle. Expressed in several structures, including head and tail. Human ortholog(s) of this gene implicated in Raynaud-Claes syndrome and X-linked recessive disease (multiple). Is an ortholog of human CLCN4 (chloride voltage-gated channel 4). WB:WBGene00000533 clh-6 Predicted to enable chloride transmembrane transporter activity. Involved in lysosomal protein catabolic process. Predicted to be located in lysosomal membrane. Expressed in several structures, including body wall musculature; head; intestine; non-striated muscle; and tail. Human ortholog(s) of this gene implicated in autosomal dominant osteopetrosis 2 and autosomal recessive osteopetrosis 4. Is an ortholog of human CLCN7 (chloride voltage-gated channel 7). WB:WBGene00000534 cpi-2 Enables cysteine-type endopeptidase inhibitor activity. Involved in positive regulation of vitellogenesis; regulation of oocyte development; and regulation of protein processing. Located in extracellular space and yolk granule. Expressed in hypodermis; pharyngeal gland cell; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of several human genes including CST1 (cystatin SN); CST2 (cystatin SA); and CST3 (cystatin C). WB:WBGene00000535 cpi-1 Enables cysteine-type endopeptidase inhibitor activity. Predicted to be located in cytoplasm; extracellular space; and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of human CST1 (cystatin SN); CST3 (cystatin C); and CST4 (cystatin S). WB:WBGene00000536 clk-1 Enables transcription cis-regulatory region binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of multicellular organismal process; and regulation of macromolecule metabolic process. Located in mitochondrion and nucleus. Expressed widely. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 8. Is an ortholog of human COQ7 (coenzyme Q7, hydroxylase). WB:WBGene00000537 clk-2 Predicted to enable Hsp90 protein binding activity and telomeric DNA binding activity. Involved in several processes, including DNA damage checkpoint signaling; determination of adult lifespan; and response to radiation. Located in cytoplasm. Expressed in several structures, including distal tip cell; gonad; head ganglion; and preanal ganglion neurons. Is an ortholog of human TELO2 (telomere maintenance 2). WB:WBGene00000538 clk-3 Acts upstream of or within determination of adult lifespan. WB:WBGene00000539 cln-3.1 Involved in determination of adult lifespan and regulation of egg-laying behavior. Located in cytoplasm. Expressed in cuticle; diagonal muscle; hypodermis; intestine; and pharynx. Used to study neuronal ceroid lipofuscinosis. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 3. Is an ortholog of human CLN3 (CLN3 lysosomal/endosomal transmembrane protein, battenin). WB:WBGene00000540 cln-3.2 Involved in determination of adult lifespan and regulation of egg-laying behavior. Predicted to be located in lysosome. Used to study neuronal ceroid lipofuscinosis. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 3. Is an ortholog of human CLN3 (CLN3 lysosomal/endosomal transmembrane protein, battenin). WB:WBGene00000541 cln-3.3 Involved in determination of adult lifespan and regulation of egg-laying behavior. Predicted to be located in lysosome. Used to study neuronal ceroid lipofuscinosis. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 3. Is an ortholog of human CLN3 (CLN3 lysosomal/endosomal transmembrane protein, battenin). WB:WBGene00000542 clp-1 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Involved in several processes, including cellular response to calcium ion; muscle cell cellular homeostasis; and positive regulation of sarcomere organization. Located in M band. Expressed in GABAergic neurons; hypodermis; intestine; pharyngeal muscle cell; and vulva. Used to study Duchenne muscular dystrophy and hereditary spastic paraplegia. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant limb-girdle muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2A; hereditary spastic paraplegia 76; and stomach cancer. Is an ortholog of human CAPN3 (calpain 3) and CAPN9 (calpain 9). WB:WBGene00000543 clp-2 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Expressed in head; hypodermis; intestinal cell; muscle cell; and tail. Is an ortholog of human CAPN7 (calpain 7). WB:WBGene00000544 clp-3 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant limb-girdle muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2A; hereditary spastic paraplegia 76; and stomach cancer. Is an ortholog of several human genes including CAPN1 (calpain 1); CAPN2 (calpain 2); and CAPN3 (calpain 3). WB:WBGene00000545 clp-4 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Expressed in GABAergic neurons; body wall musculature; dorsal nerve cord; and ventral nerve cord. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant limb-girdle muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2A; hereditary spastic paraplegia 76; and stomach cancer. Is an ortholog of several human genes including CAPN1 (calpain 1); CAPN2 (calpain 2); and CAPN3 (calpain 3). WB:WBGene00000546 clp-6 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Expressed in hypodermis. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant limb-girdle muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2A; hereditary spastic paraplegia 76; and stomach cancer. Is an ortholog of several human genes including CAPN1 (calpain 1); CAPN2 (calpain 2); and CAPN3 (calpain 3). WB:WBGene00000547 clp-7 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Expressed in several structures, including excretory cell; hypodermis; neurons; ventral nerve cord; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant limb-girdle muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2A; and hereditary spastic paraplegia 76. Is an ortholog of human CAPN3 (calpain 3). WB:WBGene00000548 clr-1 Enables transmembrane receptor protein tyrosine phosphatase activity. Involved in several processes, including negative regulation of fibroblast growth factor receptor signaling pathway; netrin-activated signaling pathway; and positive regulation of synapse assembly. Located in plasma membrane and postsynapse. Expressed in several structures, including AVA; body wall musculature; muscle cell; preanal ganglion; and somatic gonad. Human ortholog(s) of this gene implicated in gastric adenocarcinoma; multiple sclerosis; and severe combined immunodeficiency. Is an ortholog of human PTPRC (protein tyrosine phosphatase receptor type C); PTPRG (protein tyrosine phosphatase receptor type G); and PTPRZ1 (protein tyrosine phosphatase receptor type Z1). WB:WBGene00000549 cls-2 Predicted to enable microtubule binding activity. Involved in cytoplasmic streaming; mitotic cytokinesis; and organelle organization. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and nucleus. Expressed in embryonic cell. Is an ortholog of human CLASP2 (cytoplasmic linker associated protein 2). WB:WBGene00000550 clu-1 Predicted to enable mRNA binding activity. Predicted to be involved in intracellular distribution of mitochondria. Predicted to be located in cytoplasm. Is an ortholog of human CLUH (clustered mitochondria homolog). WB:WBGene00000551 clx-1 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; procyanidin; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00000552 cmd-1 Predicted to enable calcium ion binding activity and enzyme regulator activity. Involved in several processes, including apoptotic cell clearance; establishment of meiotic spindle orientation; and positive chemotaxis. Located in cell periphery; microtubule cytoskeleton; and nuclear membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; catecholaminergic polymorphic ventricular tachycardia 4; intrinsic cardiomyopathy (multiple); and major depressive disorder. Is an ortholog of human CALM1 (calmodulin 1); CALM2 (calmodulin 2); and CALM3 (calmodulin 3). WB:WBGene00000553 cmk-1 Enables calmodulin binding activity and calmodulin-dependent protein kinase activity. Involved in several processes, including neuron projection morphogenesis; positive regulation of transcription by RNA polymerase II; and thermosensory behavior. Located in cytoplasm and nucleus. Expressed in neurons and vulval muscle. Is an ortholog of human CAMK1 (calcium/calmodulin dependent protein kinase I). WB:WBGene00000554 cnb-1 Enables calcium ion binding activity. Predicted to be involved in calcineurin-mediated signaling. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Expressed in several structures, including germ line; gonad; muscle cell; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease and dilated cardiomyopathy. Is an ortholog of human PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha). WB:WBGene00000555 cnc-1 Involved in defense response to fungus and innate immune response. Predicted to be located in membrane. WB:WBGene00000556 cnc-2 Involved in defense response to Gram-negative bacterium; defense response to fungus; and innate immune response. Predicted to be located in extracellular space. Expressed in hypodermis. WB:WBGene00000557 cnc-3 Enriched in germline precursor cell; hypodermis; intestine; male-specific anatomical entity; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including Ethanol; methylmercury hydroxide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00000558 cnc-4 Involved in defense response to fungus and innate immune response. Predicted to be located in membrane. Expressed in hypodermis; intestine; and seam cell. WB:WBGene00000559 cnc-5 Involved in defense response to fungus and innate immune response. WB:WBGene00000560 cnc-6 Involved in defense response to fungus and innate immune response. Expressed in intestine. WB:WBGene00000561 cnd-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Involved in axonal fasciculation and negative regulation of gliogenesis. Located in nucleus. Expressed in several structures, including ABalpapaa; ABalppapa; motor neurons; neuroblasts; and somatic nervous system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 72; glucose metabolism disease (multiple); and obesity. Is an ortholog of several human genes including NEUROD1 (neuronal differentiation 1); NEUROD2 (neuronal differentiation 2); and NEUROD4 (neuronal differentiation 4). WB:WBGene00000562 cng-1 Predicted to enable cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Involved in negative regulation of cGMP-mediated signaling; response to oxygen levels; and sensory perception. Located in neuronal cell body. Expressed in amphid neurons and head neurons. WB:WBGene00000563 cng-3 Predicted to enable cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Involved in multicellular organismal reproductive process; positive regulation of growth rate; and response to heat. Located in non-motile cilium. Expressed in amphid neurons. WB:WBGene00000564 cnk-1 Predicted to be located in cytoplasm and membrane. Human ortholog(s) of this gene implicated in syndromic X-linked mental retardation Hough type. Is an ortholog of human CNKSR2 (connector enhancer of kinase suppressor of Ras 2). WB:WBGene00000565 cnt-1 Enables phosphatidylinositol phosphate binding activity and small GTPase binding activity. Involved in apoptotic process; negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; and positive regulation of endosome to plasma membrane protein transport. Located in basolateral plasma membrane; cytoplasmic side of apical plasma membrane; and endosome membrane. Used to study cancer. Is an ortholog of human ACAP1 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 1); ACAP2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2); and ACAP3 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 3). WB:WBGene00000566 cnt-2 Predicted to enable GTPase activator activity and GTPase activity. Involved in asymmetric neuroblast division; cell fate determination involved in pattern specification; and regulation of receptor-mediated endocytosis. Expressed in tail. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma and prostate cancer. Is an ortholog of human AGAP3 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 3). WB:WBGene00000567 cnx-1 Enables calcium ion binding activity. Involved in IRE1-mediated unfolded protein response and response to heat. Located in perinuclear region of cytoplasm. Expressed in copulatory spicule; excretory cell; nervous system; seam cell; and spermatheca. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human CANX (calnexin) and CLGN (calmegin). WB:WBGene00000568 cod-1 No description available WB:WBGene00000569 cod-2 No description available WB:WBGene00000570 cod-3 No description available WB:WBGene00000571 cod-4 No description available WB:WBGene00000572 cod-5 No description available WB:WBGene00000573 cod-6 No description available WB:WBGene00000574 cod-7 No description available WB:WBGene00000575 cod-8 No description available WB:WBGene00000576 cod-9 No description available WB:WBGene00000577 cod-10 No description available WB:WBGene00000578 cod-11 No description available WB:WBGene00000579 cod-12 No description available WB:WBGene00000580 cod-13 No description available WB:WBGene00000581 cod-14 No description available WB:WBGene00000582 cod-15 No description available WB:WBGene00000583 cof-2 Predicted to be involved in signal transduction. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Is an ortholog of human GLDN (gliomedin). WB:WBGene00000584 cog-1 Enables DNA-binding transcription factor binding activity. Involved in several processes, including determination of left/right symmetry; neuron development involved in amphid sensory organ development; and regulation of gene expression. Predicted to be located in nucleus. Expressed in several structures, including body ganglion; egg-laying apparatus; head neurons; male-specific anatomical entity; and tail ganglion. Human ortholog(s) of this gene implicated in spastic ataxia 8. Is an ortholog of human NKX6-1 (NK6 homeobox 1) and NKX6-2 (NK6 homeobox 2). WB:WBGene00000585 cogc-2 Involved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIq. Is an ortholog of human COG2 (component of oligomeric golgi complex 2). WB:WBGene00000591 coh-1 Predicted to enable chromatin binding activity. Predicted to be involved in replication-born double-strand break repair via sister chromatid exchange and sister chromatid cohesion. Predicted to be located in nucleus. Predicted to be part of cohesin complex. Expressed in several structures, including anterior distal tip cell; anterior gonad arm; germ line; and posterior distal tip cell. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 4; carcinoma (multiple); and endometrial cancer. Is an ortholog of human RAD21 (RAD21 cohesin complex component) and RAD21L1 (RAD21 cohesin complex component like 1). WB:WBGene00000592 coh-3 Involved in meiotic sister chromatid cohesion. WB:WBGene00000593 col-2 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000594 col-3 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000595 col-5 No description available WB:WBGene00000596 col-7 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Expressed in seam cell. WB:WBGene00000597 col-8 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000598 col-9 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000599 col-10 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000600 col-11 No description available WB:WBGene00000601 col-12 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000602 col-13 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000603 col-14 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in Stickler syndrome and multiple epiphyseal dysplasia 6. Is an ortholog of human COL9A1 (collagen type IX alpha 1 chain). WB:WBGene00000604 col-15 No description available WB:WBGene00000605 col-16 No description available WB:WBGene00000606 col-17 Predicted to be part of collagen trimer. WB:WBGene00000607 col-18 No description available WB:WBGene00000608 col-19 A structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in alae of collagen and cuticulin-based cuticle extracellular matrix and annuli extracellular matrix. Expressed in cuticle; hyp7 syncytium; syncytium; vulva; and in male. WB:WBGene00000609 col-20 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000610 col-33 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Is an ortholog of human COL21A1 (collagen type XXI alpha 1 chain). WB:WBGene00000611 col-34 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000612 col-35 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000613 col-36 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Is an ortholog of human COL21A1 (collagen type XXI alpha 1 chain). WB:WBGene00000614 col-37 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000615 col-38 Predicted to be a structural constituent of cuticle. Involved in collagen and cuticulin-based cuticle development. Predicted to be located in nucleus. Expressed in hyp7 syncytium and seam cell. WB:WBGene00000616 col-39 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000617 col-40 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Expressed in hypodermis. WB:WBGene00000618 col-41 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Expressed in hypodermis and vulval precursor cell. WB:WBGene00000620 col-43 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Expressed in hypodermis. Is an ortholog of human C1QTNF9 (C1q and TNF related 9); C1QTNF9B (C1q and TNF related 9B); and OTOL1 (otolin 1). WB:WBGene00000621 col-44 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000622 col-45 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000623 col-46 Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000624 col-47 Predicted to be part of collagen trimer. WB:WBGene00000625 col-48 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000626 col-49 Predicted to be a structural constituent of cuticle. Involved in collagen and cuticulin-based cuticle development. Expressed in hyp7 syncytium and seam cell. WB:WBGene00000627 col-50 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000628 col-51 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000629 col-52 Predicted to be part of collagen trimer. WB:WBGene00000630 col-53 Predicted to be located in membrane. WB:WBGene00000631 col-54 Predicted to be a structural constituent of cuticle. Involved in defense response to Gram-negative bacterium. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000632 col-55 Predicted to be part of collagen trimer. WB:WBGene00000633 col-56 Predicted to be located in membrane. WB:WBGene00000634 col-58 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 5. Is an ortholog of human COLQ (collagen like tail subunit of asymmetric acetylcholinesterase). WB:WBGene00000636 col-60 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000637 col-61 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000638 col-62 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000639 col-63 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000640 col-64 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000641 col-65 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000642 col-66 Is affected by several genes including daf-2; prg-1; and osm-3 based on RNA-seq and microarray studies. Is affected by five chemicals including Hydrolyzable Tannins; Colistin; and dafa#1 based on microarray studies. WB:WBGene00000644 col-68 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000645 col-69 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000646 H17B01.2 Predicted to be part of collagen trimer. WB:WBGene00000647 col-71 Predicted to be a structural constituent of cuticle. Involved in collagen and cuticulin-based cuticle development. Predicted to be located in membrane and nucleus. Expressed in hyp7 syncytium and seam cell. WB:WBGene00000648 col-72 Predicted to be located in membrane. Predicted to be part of collagen trimer. Is an ortholog of human COL24A1 (collagen type XXIV alpha 1 chain). WB:WBGene00000649 col-73 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000650 col-74 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000651 col-75 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000652 col-76 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000653 col-77 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in Bethlem myopathy and Ullrich congenital muscular dystrophy. Is an ortholog of human COL6A2 (collagen type VI alpha 2 chain). WB:WBGene00000654 col-78 Predicted to be located in membrane. WB:WBGene00000655 col-79 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000656 col-80 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Is an ortholog of human COL21A1 (collagen type XXI alpha 1 chain). WB:WBGene00000657 col-81 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000658 col-83 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000659 col-84 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 5. Is an ortholog of human COLQ (collagen like tail subunit of asymmetric acetylcholinesterase). WB:WBGene00000660 col-85 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000661 col-86 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000662 col-87 Predicted to be part of collagen trimer. WB:WBGene00000663 col-88 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000664 col-89 Predicted to be a structural constituent of cuticle. Involved in IRE1-mediated unfolded protein response. Predicted to be part of collagen trimer. Expressed in head; neurons; and tail. WB:WBGene00000665 col-90 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000666 col-91 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000667 col-92 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Expressed in hypodermis. WB:WBGene00000668 col-93 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000669 col-94 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000670 col-95 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000671 col-96 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000672 col-97 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000673 col-98 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000674 col-99 Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in axon guidance. Located in extracellular space; neuromuscular junction; and plasma membrane. Part of collagen trimer. Expressed in anal depressor muscle; body wall musculature; hypodermis; neurons; and retrovesicular ganglion. Human ortholog(s) of this gene implicated in congenital fibrosis of the extraocular muscles 5. Is an ortholog of human COL23A1 (collagen type XXIII alpha 1 chain) and COL25A1 (collagen type XXV alpha 1 chain). WB:WBGene00000675 col-101 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000676 col-102 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000677 col-103 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000678 col-104 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000679 col-105 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000680 col-106 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000681 col-107 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000682 col-108 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000683 col-109 Predicted to be a structural constituent of cuticle. Involved in IRE1-mediated unfolded protein response. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000684 col-110 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000685 col-111 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000687 col-113 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000688 col-114 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000689 col-115 Predicted to be located in membrane. WB:WBGene00000690 col-116 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000691 col-117 Predicted to be a structural constituent of cuticle. WB:WBGene00000692 col-118 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000693 col-119 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in artery disease (multiple); brain small vessel disease 2; and porencephaly. Is an ortholog of human COL4A2 (collagen type IV alpha 2 chain). WB:WBGene00000694 col-120 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000695 col-121 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Expressed in hyp7 syncytium. WB:WBGene00000696 col-122 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000697 col-123 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in Bethlem myopathy; Ullrich congenital muscular dystrophy; and congenital myasthenic syndrome 5. Is an ortholog of human COL6A2 (collagen type VI alpha 2 chain) and COLQ (collagen like tail subunit of asymmetric acetylcholinesterase). WB:WBGene00000698 col-124 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000699 col-125 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000700 col-126 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000701 col-127 Predicted to be a structural constituent of cuticle. WB:WBGene00000702 col-128 Predicted to be located in membrane. WB:WBGene00000703 col-129 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000704 col-130 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Expressed in intestine and vulva. WB:WBGene00000705 col-131 Predicted to be located in membrane. WB:WBGene00000706 col-132 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000707 col-133 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000708 col-135 Predicted to be located in extracellular matrix and extracellular space. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in Stickler syndrome and multiple epiphyseal dysplasia 2. Is an ortholog of human COL9A2 (collagen type IX alpha 2 chain). WB:WBGene00000709 col-136 Is affected by several genes including rrf-3; sir-2.1; and prg-1 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00000710 col-137 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000711 col-138 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000712 col-139 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000713 col-140 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000714 col-141 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in Bethlem myopathy and Ullrich congenital muscular dystrophy. Is an ortholog of human COL6A2 (collagen type VI alpha 2 chain). WB:WBGene00000715 col-142 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000716 col-143 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000717 col-144 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Expressed in hypodermis. WB:WBGene00000718 col-145 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000719 col-146 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000720 col-147 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000721 col-148 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000722 col-149 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000723 col-150 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000724 col-151 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000725 col-152 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Is an ortholog of human COL21A1 (collagen type XXI alpha 1 chain). WB:WBGene00000726 col-153 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000727 col-154 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000728 col-155 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000729 col-156 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000730 col-157 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000731 col-158 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000732 col-159 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000733 col-160 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000734 col-161 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000735 col-162 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000736 col-163 Predicted to be located in membrane. WB:WBGene00000737 col-164 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000738 col-165 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000739 col-166 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000740 col-167 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000741 col-168 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000742 col-169 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000743 col-170 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000744 col-171 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000745 col-172 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000746 col-173 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000747 col-174 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000748 col-175 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Is an ortholog of human COL21A1 (collagen type XXI alpha 1 chain). WB:WBGene00000749 col-176 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000750 col-177 Predicted to be located in membrane. WB:WBGene00000751 col-178 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Expressed widely. WB:WBGene00000752 col-179 Predicted to be a structural constituent of cuticle. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in Stickler syndrome; multiple epiphyseal dysplasia 2; and pulmonary tuberculosis. Is an ortholog of human COL9A2 (collagen type IX alpha 2 chain) and MARCO (macrophage receptor with collagenous structure). WB:WBGene00000753 col-180 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000754 col-181 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Is an ortholog of human COL5A3 (collagen type V alpha 3 chain) and MARCO (macrophage receptor with collagenous structure). WB:WBGene00000755 col-182 Enriched in AFD; PLM; hypodermis; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-six chemicals including methylmercury hydroxide; 1-methylnicotinamide; and nicotinic acid based on RNA-seq; microarray; and proteomic studies. WB:WBGene00000756 col-183 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Expressed in hypodermis. WB:WBGene00000757 col-184 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000758 col-185 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00000759 col-186 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00000760 col-187 Predicted to be located in membrane. WB:WBGene00000761 coq-1 Predicted to enable prenyltransferase activity. Involved in ubiquinone biosynthetic process. Predicted to be extrinsic component of mitochondrial inner membrane. Predicted to be part of transferase complex. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 2. Is an ortholog of human PDSS1 (decaprenyl diphosphate synthase subunit 1). WB:WBGene00000762 coq-2 Predicted to enable 4-hydroxybenzoate decaprenyltransferase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrial membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 1. Is an ortholog of human COQ2 (coenzyme Q2, polyprenyltransferase). WB:WBGene00000763 coq-3 Predicted to enable hexaprenyldihydroxybenzoate methyltransferase activity. Involved in nematode larval development and ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Is an ortholog of human COQ3 (coenzyme Q3, methyltransferase). WB:WBGene00000764 coq-4 Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Predicted to be extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 7. Is an ortholog of human COQ4 (coenzyme Q4). WB:WBGene00000765 coq-5 Predicted to enable methyltransferase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 9. Is an ortholog of human COQ5 (coenzyme Q5, methyltransferase). WB:WBGene00000766 coq-6 Predicted to enable oxidoreductase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 6. Is an ortholog of human COQ6 (coenzyme Q6, monooxygenase). WB:WBGene00000767 coq-8 Predicted to enable ATP binding activity and transferase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Expressed in coelomocyte; hypodermis; muscle cell; and neurons. Human ortholog(s) of this gene implicated in nephrotic syndrome type 9 and primary coenzyme Q10 deficiency 4. Is an ortholog of human COQ8A (coenzyme Q8A) and COQ8B (coenzyme Q8B). WB:WBGene00000768 cor-1 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to be located in cytoplasm and cytoskeleton. Expressed in several structures, including QL.a; QL.pa; QR.a; QR.pa; and oxygen sensory neurons. Human ortholog(s) of this gene implicated in coronin-1A deficiency. Is an ortholog of several human genes including CORO1A (coronin 1A); CORO1B (coronin 1B); and CORO1C (coronin 1C). WB:WBGene00000769 cow-1 No description available WB:WBGene00000770 cpb-1 Predicted to enable mRNA 3'-UTR binding activity; ribosome binding activity; and translation regulator activity, nucleic acid binding. Involved in meiotic cell cycle and spermatogenesis. Located in cytoplasm. Expressed in Z2; Z3; and germ line. Human ortholog(s) of this gene implicated in portal hypertension and primary biliary cholangitis. Is an ortholog of human CPEB2 (cytoplasmic polyadenylation element binding protein 2). WB:WBGene00000771 cpb-2 Predicted to enable mRNA 3'-UTR binding activity; ribosome binding activity; and translation regulator activity, nucleic acid binding. Predicted to be involved in negative regulation of cytoplasmic translation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of messenger ribonucleoprotein complex. WB:WBGene00000772 cpb-3 Predicted to enable mRNA 3'-UTR binding activity; ribosome binding activity; and translation regulator activity, nucleic acid binding. Predicted to be involved in negative regulation of cytoplasmic translation. Predicted to be located in several cellular components, including neuron projection; nucleus; and synapse. Predicted to be part of messenger ribonucleoprotein complex. Expressed in PVDL; PVDR; and germ line. Human ortholog(s) of this gene implicated in liver cirrhosis. Is an ortholog of human CPEB1 (cytoplasmic polyadenylation element binding protein 1). WB:WBGene00000773 cpf-1 Predicted to be involved in mRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage stimulating factor complex. Is an ortholog of human CSTF1 (cleavage stimulation factor subunit 1). WB:WBGene00000774 cpf-2 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA 3'-end processing. Located in nuclear speck. Is an ortholog of human CSTF2 (cleavage stimulation factor subunit 2) and CSTF2T (cleavage stimulation factor subunit 2 tau variant). WB:WBGene00000775 cpin-1 Predicted to enable deaminase activity. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in stomach cancer. Is an ortholog of human GDA (guanine deaminase). WB:WBGene00000776 cpl-1 Predicted to enable cysteine-type endopeptidase activity. Involved in several processes, including lipid droplet disassembly; positive regulation of vitellogenesis; and regulation of apoptosis involved in tissue homeostasis. Located in several cellular components, including lysosome; vesicle lumen; and yolk granule. Expressed in several structures, including cuticle; eggshell; hermaphrodite gonad; pharynx; and vulva. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy and type 2 diabetes mellitus. Is an ortholog of human CTSL (cathepsin L). WB:WBGene00000777 cpn-1 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to be located in actin cytoskeleton. WB:WBGene00000778 cpn-2 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to be located in actin cytoskeleton. Is an ortholog of human TAGLN (transgelin). WB:WBGene00000779 cpn-3 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Located in myofibril. Expressed in anal region; body wall musculature; egg-laying apparatus; enteric muscle; and head neurons. WB:WBGene00000780 cpn-4 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to be located in actin cytoskeleton. WB:WBGene00000781 cpr-1 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). WB:WBGene00000782 cpr-2 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. WB:WBGene00000783 cpr-3 Predicted to enable cysteine-type endopeptidase activity. Involved in innate immune response. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). WB:WBGene00000784 cpr-4 Enables cysteine-type endopeptidase activity. Involved in cellular response to UV; cellular response to gamma radiation; and proteolysis involved in protein catabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). WB:WBGene00000785 cpr-5 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). WB:WBGene00000786 cpr-6 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). WB:WBGene00000787 cps-6 Enables endonuclease activity; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Located in mitochondrion. Is an ortholog of human ENDOG (endonuclease G). WB:WBGene00000788 cpz-1 Predicted to enable cysteine-type endopeptidase activity. Involved in several processes, including ecdysis, collagen and cuticulin-based cuticle; gonad morphogenesis; and post-embryonic development. Located in collagen and cuticulin-based cuticle extracellular matrix; extracellular space; and yolk granule. Expressed in several structures, including anterior hypodermis; cuticle; intestine; pharynx; and vulva. Is an ortholog of human CTSZ (cathepsin Z). WB:WBGene00000789 cpz-2 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSZ (cathepsin Z). WB:WBGene00000792 crb-1 Predicted to enable calcium ion binding activity. Predicted to be involved in establishment or maintenance of epithelial cell apical/basal polarity and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in apical part of cell and cytoplasm. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in eye disease (multiple); focal segmental glomerulosclerosis 9; and ventriculomegaly - cystic kidney disease. Is an ortholog of human CRB1 (crumbs cell polarity complex component 1). WB:WBGene00000793 crh-1 Enables identical protein binding activity and transcription coactivator binding activity. Involved in determination of adult lifespan; intracellular signal transduction; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Expressed in several structures, including germ line; gonad; head ganglion; intestine; and neurons. Human ortholog(s) of this gene implicated in Pick's disease and schizophrenia. Is an ortholog of human ATF1 (activating transcription factor 1); CREB1 (cAMP responsive element binding protein 1); and CREM (cAMP responsive element modulator). WB:WBGene00000794 crn-1 Enables flap endonuclease activity. Involved in apoptotic DNA fragmentation. Located in nucleus. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human FEN1 (flap structure-specific endonuclease 1). WB:WBGene00000795 crn-2 Enables DNA nuclease activity. Involved in apoptotic DNA fragmentation and apoptotic cell clearance. Predicted to be located in cytosol. Expressed in head and tail. Is an ortholog of human TATDN1 (TatD DNase domain containing 1). WB:WBGene00000796 crn-3 Predicted to enable 3'-5'-RNA exonuclease activity and single-stranded RNA binding activity. Involved in apoptotic DNA fragmentation; apoptotic cell clearance; and embryo development. Predicted to be located in nucleolus. Predicted to be part of nuclear exosome (RNase complex). Is an ortholog of human EXOSC10 (exosome component 10). WB:WBGene00000797 crn-4 Enables nuclease activity and single-stranded DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Predicted to be located in cytoplasm. Is an ortholog of human ERI1 (exoribonuclease 1). WB:WBGene00000798 crn-5 Enables double-stranded DNA binding activity and enzyme binding activity. Involved in RNA processing and apoptotic DNA fragmentation. Part of exosome (RNase complex). Is an ortholog of human EXOSC5 (exosome component 5). WB:WBGene00000799 crn-6 Enables deoxyribonuclease II activity. Involved in apoptotic DNA fragmentation. Is an ortholog of human DNASE2B (deoxyribonuclease 2 beta). WB:WBGene00000800 cars-1 Predicted to enable ATP binding activity and cysteine-tRNA ligase activity. Predicted to be involved in cysteinyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Is an ortholog of human CARS1 (cysteinyl-tRNA synthetase 1). WB:WBGene00000801 cars-2 Enriched in OLL; PVD; sensory neurons; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including rrf-3; clk-1; and isp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; rotenone; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00000802 crt-1 Enables calcium ion binding activity. Involved in several processes, including IRE1-mediated unfolded protein response; defecation; and hemidesmosome assembly. Located in cytoplasm. Expressed in several structures, including coelomocyte; excretory system; intestine; pharynx; and sperm. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in several diseases, including endocrine gland cancer (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Is an ortholog of human CALR (calreticulin). WB:WBGene00000803 csb-1 Predicted to enable ATP-dependent activity, acting on DNA and DNA binding activity. Involved in UV protection and transcription-coupled nucleotide-excision repair. Predicted to be located in nucleus. Expressed in several structures, including copulatory spicule; egg-laying apparatus; neurons; oocyte; and postcloacal sensillum. Used to study Cockayne syndrome. Human ortholog(s) of this gene implicated in several diseases, including Cockayne syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human ERCC6 (ERCC excision repair 6, chromatin remodeling factor). WB:WBGene00000804 csc-1 Involved in mitotic cleavage furrow ingression and nuclear division. Located in condensed nuclear chromosome; meiotic spindle midzone; and mitotic spindle midzone. Expressed in oocyte. WB:WBGene00000805 csg-1 No description available WB:WBGene00000806 csg-2 No description available WB:WBGene00000807 csg-3 No description available WB:WBGene00000808 csg-4 No description available WB:WBGene00000809 csg-6 No description available WB:WBGene00000810 csg-7 No description available WB:WBGene00000811 csg-8 No description available WB:WBGene00000812 csk-1 Enables protein tyrosine kinase activity. Involved in several processes, including feeding behavior; muscle cell development; and nematode larval development. Located in cell-cell junction and plasma membrane. Expressed in several structures, including anus; head neurons; hermaphrodite somatic gonadal cell; pharyngeal muscle cell; and vulval cell. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human CSK (C-terminal Src kinase). WB:WBGene00000813 csn-1 Predicted to be involved in oogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of COP9 signalosome. Is an ortholog of human GPS1 (G protein pathway suppressor 1). WB:WBGene00000814 csn-2 Predicted to be involved in oogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of COP9 signalosome. Expressed in head. Is an ortholog of human COPS2 (COP9 signalosome subunit 2). WB:WBGene00000815 csn-3 Involved in establishment of mitotic spindle localization; mitotic cytokinesis; and ubiquitin-dependent protein catabolic process. Part of COP9 signalosome. Is an ortholog of human COPS3 (COP9 signalosome subunit 3). WB:WBGene00000816 csn-4 Predicted to be involved in oogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of COP9 signalosome. Is an ortholog of human COPS4 (COP9 signalosome subunit 4). WB:WBGene00000817 csn-5 Enables DEAD/H-box RNA helicase binding activity. Involved in gonad development and oogenesis. Located in A band and nucleus. Expressed in tail. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human COPS5 (COP9 signalosome subunit 5). WB:WBGene00000818 csn-6 Predicted to enable metallopeptidase activity. Predicted to be involved in oogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of COP9 signalosome. Is an ortholog of human COPS6 (COP9 signalosome subunit 6). WB:WBGene00000819 csp-1 Enables cysteine-type endopeptidase activity. Involved in several processes, including negative regulation of cellular response to manganese ion; positive regulation of apoptotic process; and positive regulation of cellular response to gamma radiation. Located in germ cell nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); gastrointestinal system cancer (multiple); and prostate disease (multiple). Is an ortholog of several human genes including CASP3 (caspase 3); CASP6 (caspase 6); and CASP7 (caspase 7). WB:WBGene00000820 csp-2 Enables caspase binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and zymogen binding activity. Involved in positive regulation of brood size; positive regulation of fertilization; and regulation of apoptotic process. Part of protease inhibitor complex. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); chronic myeloid leukemia; and ductal carcinoma in situ. Is an ortholog of human CASP6 (caspase 6). WB:WBGene00000821 csp-3 Enables caspase binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and zymogen binding activity. Involved in positive regulation of behavior; positive regulation of embryonic development; and regulation of apoptotic process. Located in cytoplasm. Expressed in several structures, including germ line. WB:WBGene00000822 csq-1 Enables calcium ion binding activity. Involved in calcium ion homeostasis. Located in several cellular components, including apical plasma membrane; nucleus; and sarcolemma. Expressed in body wall musculature; isthmus; terminal bulb; and vulval muscle. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia 2 and type 2 diabetes mellitus. Is an ortholog of human CASQ1 (calsequestrin 1) and CASQ2 (calsequestrin 2). WB:WBGene00000824 cta-1 No description available WB:WBGene00000825 cta-2 No description available WB:WBGene00000826 cta-3 No description available WB:WBGene00000827 cta-4 No description available WB:WBGene00000828 cta-5 No description available WB:WBGene00000829 ctb-1 Predicted to enable electron transfer activity and metal ion binding activity. Predicted to contribute to ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex III. WB:WBGene00000830 ctl-1 Enables catalase activity. Predicted to be involved in hydrogen peroxide catabolic process and response to hydrogen peroxide. Predicted to be located in mitochondrion and peroxisome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Is an ortholog of human CAT (catalase). WB:WBGene00000831 ctl-2 Enables catalase activity. Involved in determination of adult lifespan and peroxisome organization. Located in peroxisome. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Is an ortholog of human CAT (catalase). WB:WBGene00000832 ctn-1 Predicted to enable actin filament binding activity and cadherin binding activity. Involved in regulation of locomotion. Located in plasma membrane and striated muscle dense body. Expressed in body wall musculature; non-striated muscle; and somatic nervous system. Used to study Duchenne muscular dystrophy. Is an ortholog of human CTNNAL1 (catenin alpha like 1). WB:WBGene00000833 cts-1 Predicted to enable citrate (Si)-synthase activity. Predicted to be involved in carbohydrate metabolic process and tricarboxylic acid cycle. Located in mitochondrion. Expressed in anal depressor muscle and ventral cord neurons. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and hypertrophic cardiomyopathy. Is an ortholog of human CS (citrate synthase). WB:WBGene00000834 cua-1 Enables copper ion transmembrane transporter activity. Involved in copper ion transport. Located in vacuolar membrane. Expressed in neurons; pharynx; and pm6. Used to study Menkes disease. Human ortholog(s) of this gene implicated in several diseases, including Menkes disease; Wilson disease; and X-linked recessive disease (multiple). Is an ortholog of human ATP7A (ATPase copper transporting alpha). WB:WBGene00000835 cuc-1 Enables copper chaperone activity. Involved in copper ion transport. Located in cytosol. Expressed in hyp5; hyp6; and hyp7 syncytium. Is an ortholog of human ATOX1 (antioxidant 1 copper chaperone). WB:WBGene00000836 cul-1 Predicted to enable protein-macromolecule adaptor activity and ubiquitin protein ligase binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of cell cycle; and regulation of apoptotic process. Predicted to be located in cytoplasm. Predicted to be part of SCF ubiquitin ligase complex. Expressed in intestine; muscle cell; and neurons. Is an ortholog of human CUL1 (cullin 1). WB:WBGene00000837 cul-2 Predicted to enable protein-macromolecule adaptor activity and ubiquitin protein ligase binding activity. Involved in several processes, including anaphase-promoting complex-dependent catabolic process; positive regulation of metaphase/anaphase transition of meiotic cell cycle; and reproductive process. Located in cytoplasm and nucleus. Part of Cul2-RING ubiquitin ligase complex. Expressed in several structures, including P1; P12; P2; germ line; and nerve ring. Is an ortholog of human CUL2 (cullin 2). WB:WBGene00000838 cul-3 Enables POZ domain binding activity. Involved in cell development and protein metabolic process. Part of Cul3-RING ubiquitin ligase complex. Expressed in head; linker cell; and tail. Human ortholog(s) of this gene implicated in pseudohypoaldosteronism. Is an ortholog of human CUL3 (cullin 3). WB:WBGene00000839 cul-4 Predicted to enable ubiquitin protein ligase binding activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Expressed in embryonic cell; germ line; gonad; intestine; and oocyte. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Cabezas type. Is an ortholog of human CUL4B (cullin 4B). WB:WBGene00000840 cul-5 Predicted to enable protein-macromolecule adaptor activity and ubiquitin protein ligase binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be part of Cul5-RING ubiquitin ligase complex and SCF ubiquitin ligase complex. Expressed in several structures, including head; intestine; nervous system; tail; and vulval muscle. Is an ortholog of human CUL5 (cullin 5). WB:WBGene00000841 cul-6 Predicted to enable protein-macromolecule adaptor activity and ubiquitin protein ligase binding activity. Involved in defense response to virus. Predicted to be part of SCF ubiquitin ligase complex. Expressed in intestine and pharynx. Is an ortholog of human CUL1 (cullin 1). WB:WBGene00000842 cup-1 Acts upstream of or within endocytosis. WB:WBGene00000843 cup-2 Predicted to enable misfolded protein binding activity; signal recognition particle binding activity; and ubiquitin-specific protease binding activity. Involved in endocytosis and response to misfolded protein. Located in early endosome and perinuclear endoplasmic reticulum. Expressed widely. Is an ortholog of human DERL1 (derlin 1). WB:WBGene00000844 cup-3 Acts upstream of or within endocytosis. WB:WBGene00000845 cup-4 Predicted to enable neurotransmitter receptor activity. Involved in several processes, including determination of adult lifespan; positive regulation of egg-laying behavior; and response to caloric restriction. Located in cytoplasmic vesicle membrane. WB:WBGene00000846 cup-5 Predicted to enable NAADP-sensitive calcium-release channel activity and phosphatidylinositol-3,5-bisphosphate binding activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; determination of adult lifespan; and lysosomal lumen acidification. Located in endolysosome and lysosomal membrane. Expressed in coelomocyte; head; intestinal cell; and neurons. Used to study mucolipidosis type IV. Human ortholog(s) of this gene implicated in glycoproteinosis and mucolipidosis type IV. Is an ortholog of human MCOLN1 (mucolipin TRP cation channel 1); MCOLN2 (mucolipin TRP cation channel 2); and MCOLN3 (mucolipin TRP cation channel 3). WB:WBGene00000848 cup-8 Acts upstream of or within endocytosis. WB:WBGene00000849 cup-9 Acts upstream of or within endocytosis. WB:WBGene00000850 cup-11 Acts upstream of or within endocytosis. WB:WBGene00000851 cut-1 Predicted to be a structural constituent of cuticle. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in cuticle and seam cell. WB:WBGene00000853 cut-6 Predicted to be a structural constituent of cuticle. Located in alae of collagen and cuticulin-based cuticle extracellular matrix. Expressed in hypodermal cell. WB:WBGene00000854 cux-7 Enriched in OLL; body wall muscle cell; germ line; and interneuron based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on RNA-seq and microarray studies. Is affected by five chemicals including D-glucose; Zidovudine; and paraquat based on RNA-seq and microarray studies. Human AKAP17A enables protein kinase A binding activity. Is an ortholog of human AKAP17A (A-kinase anchoring protein 17A). WB:WBGene00000857 cwn-1 Enables receptor tyrosine kinase binding activity. Involved in several processes, including neuroblast migration; neuron migration; and positive regulation of axon guidance. Predicted to be located in extracellular space. Expressed in several structures, including CAN; hypodermal cell; intestine; muscle cell; and somatic nervous system. Human ortholog(s) of this gene implicated in Mullerian aplasia and hyperandrogenism and endometrial carcinoma. Is an ortholog of human WNT4 (Wnt family member 4). WB:WBGene00000858 cwn-2 Predicted to enable cytokine activity and frizzled binding activity. Involved in several processes, including neuroblast migration; neuron migration; and pattern specification process. Predicted to be located in extracellular space. Expressed in several structures, including P5.ppp; P7.paa; RME; pharynx; and rectal gland cell. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant Robinow syndrome 1; endometrial carcinoma; and germ cell cancer (multiple). Is an ortholog of human WNT5A (Wnt family member 5A) and WNT5B (Wnt family member 5B). WB:WBGene00000859 cwp-1 Enriched in neurons and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00000860 cwp-2 Enriched in neurons and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and rrf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00000861 cwp-3 Enriched in neurons and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; alg-1; and csr-1 based on tiling array and RNA-seq studies. Is affected by Rifampin and Sirolimus based on RNA-seq studies. WB:WBGene00000862 cwp-4 Enriched in head mesodermal cell; neurons; and ray based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; daf-12; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Sodium Chloride and antimycin based on RNA-seq studies. WB:WBGene00000863 cya-1 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in meiotic cell cycle. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin A2-CDK2 complex. Human ortholog(s) of this gene implicated in acute myeloid leukemia; embryonal carcinoma; and prostate cancer. Is an ortholog of human CCNA1 (cyclin A1) and CCNA2 (cyclin A2). WB:WBGene00000864 cya-2 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in mitotic cell cycle phase transition. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin A2-CDK2 complex. WB:WBGene00000865 cyb-1 Enables cyclin-dependent protein serine/threonine kinase regulator activity and ubiquitin protein ligase binding activity. Involved in mitotic cell cycle; oocyte maturation; and positive regulation of protein phosphorylation. Located in cytoplasm and nucleus. Expressed in germ cell; male gonad; and oocyte. Human ortholog(s) of this gene implicated in several diseases, including in situ carcinoma; renal cell carcinoma; and reproductive organ cancer (multiple). Is an ortholog of human CCNB1 (cyclin B1). WB:WBGene00000866 cyb-2.1 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in anterior/posterior axis specification, embryo and oocyte maturation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including in situ carcinoma; renal cell carcinoma; and reproductive organ cancer (multiple). Is an ortholog of human CCNB1 (cyclin B1). WB:WBGene00000867 cyb-2.2 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in anterior/posterior axis specification, embryo; meiotic cell cycle; and oocyte maturation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Human ortholog(s) of this gene implicated in several diseases, including in situ carcinoma; renal cell carcinoma; and reproductive organ cancer (multiple). Is an ortholog of human CCNB1 (cyclin B1). WB:WBGene00000868 cyb-3 Enables cyclin-dependent protein serine/threonine kinase regulator activity. Involved in several processes, including chromosome organization; regulation of cell cycle; and sexual reproduction. Acts upstream of or within nematode male tail tip morphogenesis. Located in cytoplasm and nucleus. Expressed in several structures, including EMS; Psub2; germ cell; germ line; and male gonad. Is an ortholog of human CCNB3 (cyclin B3). WB:WBGene00000869 cyc-1 Predicted to enable electron transfer activity; heme binding activity; and metal ion binding activity. Involved in determination of adult lifespan and proton motive force-driven mitochondrial ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex III. Expressed in several structures, including germ line. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 6. Is an ortholog of human CYC1 (cytochrome c1). WB:WBGene00000870 cyd-1 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in several processes, including regulation of cell cycle process; regulation of cell division; and reproductive process. Acts upstream of or within nematode male tail tip morphogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Expressed in gonad; hypodermis; intestine; neurons; and vulva. Human ortholog(s) of this gene implicated in several diseases, including breast carcinoma (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human CCND3 (cyclin D3). WB:WBGene00000871 cye-1 Enables cyclin-dependent protein serine/threonine kinase regulator activity. Involved in several processes, including developmental process involved in reproduction; regulation of mitotic cell cycle; and regulation of protein localization. Located in nucleus. Part of chromatin. Expressed in several structures, including germ line; gonad; and male sex myoblast. Human ortholog(s) of this gene implicated in carcinoma (multiple); cervix uteri carcinoma in situ; and urinary bladder cancer. Is an ortholog of human CCNE1 (cyclin E1) and CCNE2 (cyclin E2). WB:WBGene00000872 cyk-1 Predicted to enable actin binding activity and small GTPase binding activity. Involved in pronuclear migration. Located in actomyosin contractile ring; cleavage furrow; and cytoplasmic side of plasma membrane. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in auditory system disease (multiple) and primary ovarian insufficiency 2A. Is an ortholog of human DIAPH1 (diaphanous related formin 1). WB:WBGene00000873 cyk-2 Acts upstream of or within embryo development and mitotic cleavage furrow formation. WB:WBGene00000874 cyk-3 Enables cysteine-type deubiquitinase activity. Involved in several processes, including cellular component organization; positive regulation of TORC1 signaling; and regulation of asymmetric protein localization involved in cell fate determination. Located in cytoplasm and microtubule organizing center. Expressed in coelomocyte; excretory cell; head neurons; hypodermis; and pharynx. Is an ortholog of human USP32 (ubiquitin specific peptidase 32). WB:WBGene00000875 cyk-4 Enables GTPase activator activity. Involved in mitotic cleavage furrow ingression; mitotic spindle midzone assembly; and polar body extrusion after meiotic divisions. Located in mitotic spindle midzone and plasma membrane. Part of centralspindlin complex. Expressed in germ cell; gonad; and tail. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia. Is an ortholog of human RACGAP1 (Rac GTPase activating protein 1). WB:WBGene00000876 cyl-1 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Acts upstream of or within nematode male tail tip morphogenesis. Predicted to be located in nucleus. Is an ortholog of human CCNL1 (cyclin L1). WB:WBGene00000877 cyn-1 Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including Bell's palsy; aggressive periodontitis; and gastrointestinal system cancer (multiple). Is an ortholog of human PPIA (peptidylprolyl isomerase A); PPIAL4C (peptidylprolyl isomerase A like 4C); and PPIF (peptidylprolyl isomerase F). WB:WBGene00000878 cyn-2 Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Bell's palsy; aggressive periodontitis; and gastrointestinal system cancer (multiple). Is an ortholog of human PPIA (peptidylprolyl isomerase A); PPIAL4C (peptidylprolyl isomerase A like 4C); and PPIF (peptidylprolyl isomerase F). WB:WBGene00000879 cyn-3 Enables peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Located in obsolete cell. Expressed in excretory system. Human ortholog(s) of this gene implicated in several diseases, including Bell's palsy; aggressive periodontitis; and gastrointestinal system cancer (multiple). Is an ortholog of human PPIA (peptidylprolyl isomerase A); PPIAL4C (peptidylprolyl isomerase A like 4C); and PPIF (peptidylprolyl isomerase F). WB:WBGene00000880 cyn-4 Predicted to enable ubiquitin protein ligase activity. Involved in feminization of hermaphroditic germ-line. Predicted to be located in nucleus. Predicted to be part of catalytic step 2 spliceosome. Expressed in body wall musculature; germ line; intestine; pharynx; and uterus. Is an ortholog of human PPIL2 (peptidylprolyl isomerase like 2). WB:WBGene00000881 cyn-5 Enables peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Located in cytoplasm. Expressed in intestine. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Is an ortholog of human PPIB (peptidylprolyl isomerase B). WB:WBGene00000882 cyn-6 Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Is an ortholog of human PPIB (peptidylprolyl isomerase B). WB:WBGene00000883 cyn-7 Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Bell's palsy; aggressive periodontitis; and gastrointestinal system cancer (multiple). Is an ortholog of human PPIA (peptidylprolyl isomerase A); PPIAL4C (peptidylprolyl isomerase A like 4C); and PPIF (peptidylprolyl isomerase F). WB:WBGene00000884 cyn-8 Enables peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Located in nucleus. Is an ortholog of human PPIG (peptidylprolyl isomerase G). WB:WBGene00000885 cyn-9 Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Expressed in hypodermis. Is an ortholog of human NKTR (natural killer cell triggering receptor). WB:WBGene00000886 cyn-10 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human PPIL3 (peptidylprolyl isomerase like 3). WB:WBGene00000887 cyn-11 Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Is an ortholog of human PPIH (peptidylprolyl isomerase H). WB:WBGene00000888 cyn-12 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be part of catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 14. Is an ortholog of human PPIL1 (peptidylprolyl isomerase like 1). WB:WBGene00000889 cyn-13 Enables nuclease activity. Involved in apoptotic DNA fragmentation. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Is an ortholog of human PPIE (peptidylprolyl isomerase E). WB:WBGene00000890 sig-7 Enables RNA polymerase II complex binding activity. Involved in nematode larval development; positive regulation of developmental process; and transcription elongation-coupled chromatin remodeling. Located in nucleoplasm. Part of euchromatin. Expressed in several structures, including intestine. Is an ortholog of human PPIL4 (peptidylprolyl isomerase like 4). WB:WBGene00000891 cyn-15 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Is an ortholog of human PPWD1 (peptidylprolyl isomerase domain and WD repeat containing 1). WB:WBGene00000892 cyn-16 Enables peptidyl-prolyl cis-trans isomerase activity. Predicted to be part of catalytic step 2 spliceosome. Expressed in intestine and ventral cord neurons. Is an ortholog of human CWC27 (CWC27 spliceosome associated cyclophilin). WB:WBGene00000893 cyn-17 Enriched in several structures, including ABplppppaa; RIH; arcade cell; germ line; and pharynx based on microarray; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including 1-methylnicotinamide; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00000894 dab-1 Enables clathrin heavy chain binding activity and protein domain specific binding activity. Involved in several processes, including ecdysis, collagen and cuticulin-based cuticle; egg-laying behavior; and positive regulation of growth rate. Located in cell cortex; clathrin-coated pit; and cytoplasmic vesicle. Expressed in several structures, including P5.ppp; amphid sheath cell; anchor cell; oocyte; and vulval cell. Human ortholog(s) of this gene implicated in autistic disorder and spinocerebellar ataxia type 37. Is an ortholog of human DAB1 (DAB adaptor protein 1). WB:WBGene00000895 dac-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in thermotaxis. Located in nucleus. Expressed in amphid neurons; cuticular ala; and tail. Is an ortholog of human DACH1 (dachshund family transcription factor 1). WB:WBGene00000896 dad-1 Involved in negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Is an ortholog of human DAD1 (defender against cell death 1). WB:WBGene00000897 daf-1 Predicted to enable activin binding activity; activin receptor activity, type I; and transforming growth factor beta receptor activity. Involved in several processes, including dauer entry; determination of adult lifespan; and response to bacterium. Predicted to be located in plasma membrane. Predicted to be part of activin receptor complex. Expressed in several structures, including distal tip cell; ganglia; inner labial sensillum; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); glaucoma (multiple); and hypertension (multiple). Is an ortholog of human ACVR1B (activin A receptor type 1B); ACVR1C (activin A receptor type 1C); and TGFBR1 (transforming growth factor beta receptor 1). WB:WBGene00000898 daf-2 Enables PTB domain binding activity; SH2 domain binding activity; and protein kinase binding activity. Involved in several processes, including dauer exit; regulation of developmental process; and regulation of macromolecule metabolic process. Acts upstream of with a negative effect on protein import into nucleus. Located in several cellular components, including cytoplasmic vesicle; neuronal cell body; and plasma membrane bounded cell projection. Expressed in several structures, including XXX cell; amphid neurons; coelomocyte; gonad; and nerve ring. Used to study Parkinson's disease and diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; glucose metabolism disease (multiple); kidney cancer (multiple); and liver disease (multiple). Is an ortholog of human IGF1R (insulin like growth factor 1 receptor); INSR (insulin receptor); and INSRR (insulin receptor related receptor). WB:WBGene00000899 daf-3 Enables cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and regulation of pharyngeal pumping. Located in condensed chromosome; cytoplasm; and nucleus. Expressed in several structures, including P1; P2; hermaphrodite distal tip cell; hypodermal cell; and neurons. WB:WBGene00000900 daf-4 Enables BMP binding activity. Involved in several processes, including defense response to other organism; regulation of BMP signaling pathway; and regulation of anatomical structure morphogenesis. Located in plasma membrane. Expressed in several structures, including ganglia; intestine; somatic nervous system; tail hypodermis; and vulva. Used to study Marfan syndrome. Human ortholog(s) of this gene implicated in several diseases, including Loeys-Dietz syndrome 2; artery disease (multiple); and gastrointestinal system cancer (multiple). Is an ortholog of human ACVR2B (activin A receptor type 2B). WB:WBGene00000901 daf-5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. Expressed in several structures, including XXX cell; ganglia; hermaphrodite distal tip cell; intestine; and muscle cell. Is an ortholog of human SKI (SKI proto-oncogene) and SKIL (SKI like proto-oncogene). WB:WBGene00000902 daf-6 Involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of dauer larval development; and regulation of insulin receptor signaling pathway. Located in cytoplasmic vesicle and plasma membrane. Expressed in several structures, including cuticle; excretory system; interfacial epithelial cell; neurons; and vulval cell. Is an ortholog of human PTCHD3 (patched domain containing 3 (gene/pseudogene)). WB:WBGene00000903 daf-7 Predicted to enable cytokine activity and transforming growth factor beta receptor binding activity. Involved in several processes, including cellular response to organic substance; regulation of gene expression; and response to bacterium. Located in extracellular space. Expressed in coelomocyte; head neurons; pharynx; and in male. Human ortholog(s) of this gene implicated in myostatin-related muscle hypertrophy and vertebral hypersegmentation and orofacial anomalies. Is an ortholog of human GDF11 (growth differentiation factor 11). WB:WBGene00000904 daf-8 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including dauer entry; determination of adult lifespan; and regulation of transcription by RNA polymerase II. Located in cytosol and nucleus. Expressed in excretory cell; hermaphrodite distal tip cell; intestine; neurons; and ventral nerve cord. WB:WBGene00000905 daf-9 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in cell-cell signaling; dauer larval development; and regulation of cell migration. Located in neuronal cell body and perinuclear region of cytoplasm. Expressed in several structures, including anterior ganglion; excretory cell; intestine; spermatheca; and vulval muscle. WB:WBGene00000906 daf-10 Involved in several processes, including non-motile cilium assembly; positive regulation of dauer larval development; and receptor localization to non-motile cilium. Located in ciliary basal body. Human ortholog(s) of this gene implicated in cranioectodermal dysplasia 1. Is an ortholog of human IFT122 (intraflagellar transport 122). WB:WBGene00000907 daf-11 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in several processes, including determination of adult lifespan; response to oxygen-containing compound; and signal transduction. Located in dendrite; neuronal cell body; and non-motile cilium. Expressed in ADLL; ADLR; ASHL; and ASHR. WB:WBGene00000908 daf-12 Enables nuclear receptor activity; sequence-specific DNA binding activity; and steroid hormone binding activity. Involved in several processes, including determination of adult lifespan; heat acclimation; and positive regulation of dauer larval development. Located in nucleus. Expressed in several structures, including gonad; neurons; pharyngeal muscle cell; somatic gonad precursor; and vulva. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); autosomal recessive limb-girdle muscular dystrophy type 2B; carcinoma (multiple); and lung disease (multiple). Is an ortholog of human VDR (vitamin D receptor). WB:WBGene00000909 daf-13 No description available WB:WBGene00000910 daf-14 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; I-SMAD binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; egg-laying behavior; and negative regulation of dauer larval development. Predicted to be part of heteromeric SMAD protein complex. Expressed in several structures, including anal sphincter muscle; excretory duct cell; intestine; nerve ring; and phasmid sheath cell. WB:WBGene00000911 daf-15 Predicted to enable protein kinase activator activity and protein-macromolecule adaptor activity. Involved in dauer larval development; determination of adult lifespan; and regulation of autophagosome assembly. Part of TORC1 complex. Expressed in several structures, including body wall musculature; excretory cell; hermaphrodite distal tip cell; intestine; and pharyngeal muscle cell. Is an ortholog of human RPTOR (regulatory associated protein of MTOR complex 1). WB:WBGene00000912 daf-16 Enables several functions, including 14-3-3 protein binding activity; beta-catenin binding activity; and enzyme binding activity. Involved in several processes, including defense response to other organism; regulation of DNA-templated transcription; and regulation of dauer larval development. Located in cytosol and nucleus. Expressed in several structures, including gonad; hypodermis; neurons; somatic cell; and ventral nerve cord. Used to study Parkinson's disease and diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; alveolar rhabdomyosarcoma; reproductive organ cancer (multiple); and rheumatoid arthritis. Is an ortholog of human FOXO4 (forkhead box O4). WB:WBGene00000913 daf-18 Enables protein tyrosine phosphatase activity. Involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis. Acts upstream of with a positive effect on protein import into nucleus. Located in several cellular components, including axon; cytoplasmic side of plasma membrane; and somatodendritic compartment. Expressed in several structures, including Z2; egg-laying apparatus; germ line; oocyte; and somatic nervous system. Used to study cancer. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and nervous system cancer (multiple). Is an ortholog of human PTEN (phosphatase and tensin homolog). WB:WBGene00000914 daf-19 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including defense response to Gram-negative bacterium; male mating behavior; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within serotonin biosynthetic process. Located in nucleus. Expressed in several structures, including body wall musculature; excretory cell; intestine; neurons; and somatic nervous system. Is an ortholog of human RFX3 (regulatory factor X3). WB:WBGene00000915 hsp-90 Enables several functions, including ATP hydrolysis activity; nuclear glucocorticoid receptor binding activity; and protein phosphatase 5 binding activity. Involved in several processes, including determination of adult lifespan; protein export from nucleus; and protein stabilization. Located in perinuclear region of cytoplasm and protein-containing complex. Expressed in several structures, including excretory system; germ line; intestine; nerve ring; and pharynx. Human ortholog(s) of this gene implicated in Alzheimer's disease; autoimmune disease (multiple); and gastrointestinal system cancer (multiple). Is an ortholog of human HSP90AB1 (heat shock protein 90 alpha family class B member 1). WB:WBGene00000917 daf-25 Predicted to enable metal ion binding activity. Involved in several processes, including dauer exit; positive regulation of cGMP-mediated signaling; and protein localization to cell periphery. Located in non-motile cilium. Expressed in intestine and sensory neurons. Is an ortholog of human ANKMY2 (ankyrin repeat and MYND domain containing 2). WB:WBGene00000918 daf-26 No description available WB:WBGene00000919 daf-27 No description available WB:WBGene00000920 daf-28 Predicted to enable insulin receptor binding activity. Involved in several processes, including insulin receptor signaling pathway; negative regulation of dauer entry; and regulation of synaptic assembly at neuromuscular junction. Acts upstream of with a negative effect on protein import into nucleus. Located in extracellular space and synapse. Expressed in several structures, including distal tip cell; egg-laying apparatus; neurons; pharynx; and ventral nerve cord. WB:WBGene00000921 daf-29 No description available WB:WBGene00000922 daf-30 No description available WB:WBGene00000923 daf-31 Predicted to enable peptide-glutamate-alpha-N-acetyltransferase activity and peptide-serine-alpha-N-acetyltransferase activity. Involved in dauer exit; determination of adult lifespan; and multicellular organism reproduction. Predicted to be part of NatA complex. Expressed in hypodermal cell and neurons. Human ortholog(s) of this gene implicated in Ogden syndrome and syndromic microphthalmia 1. Is an ortholog of human NAA10 (N-alpha-acetyltransferase 10, NatA catalytic subunit) and NAA11 (N-alpha-acetyltransferase 11, NatA catalytic subunit). WB:WBGene00000924 daf-32 No description available WB:WBGene00000925 daf-33 No description available WB:WBGene00000926 daf-34 No description available WB:WBGene00000927 daf-35 No description available WB:WBGene00000928 dao-2 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-six chemicals including methylmercury hydroxide; 1-methylnicotinamide; and manganese chloride based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00000929 dao-3 Predicted to enable methenyltetrahydrofolate cyclohydrolase activity and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in tetrahydrofolate interconversion. Predicted to be located in cytosol. Is an ortholog of human MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase). WB:WBGene00000930 dao-4 Involved in collagen and cuticulin-based cuticle development. Predicted to be located in extracellular region and nucleus. Expressed in hyp7 syncytium and seam cell. WB:WBGene00000931 dao-5 Enables RNA polymerase I core binding activity and rDNA binding activity. Involved in several processes, including determination of adult lifespan; insulin receptor signaling pathway; and nucleolar large rRNA transcription by RNA polymerase I. Located in nucleolus and nucleoplasm. Expressed in germline precursor cell; gonadal sheath cell; hypodermis; and somatic cell. Is an ortholog of human NOLC1 (nucleolar and coiled-body phosphoprotein 1). WB:WBGene00000932 dao-6 Enriched in several structures, including ABalppppaa; anterior arcade cell; excretory cell; head mesodermal cell; and pharyngeal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Cadmium Chloride; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00000933 dap-3 Predicted to be a structural constituent of ribosome. Predicted to be involved in apoptotic process. Predicted to be located in mitochondrial ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human DAP3 (death associated protein 3). WB:WBGene00000934 dat-1 Enables amine transmembrane transporter activity; chloride channel activity; and dopamine:sodium symporter activity. Involved in several processes, including cellular response to amphetamine; establishment of localization; and regulation of locomotion involved in locomotory behavior. Located in neuron projection membrane; neuronal cell body membrane; and presynaptic membrane. Expressed in dopaminergic neurons; tail; and in male. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; neurocirculatory asthenia; and nicotine dependence. Is an ortholog of human SLC6A2 (solute carrier family 6 member 2) and SLC6A3 (solute carrier family 6 member 3). WB:WBGene00000935 daz-1 Predicted to enable mRNA 3'-UTR binding activity and translation activator activity. Predicted to be involved in 3'-UTR-mediated mRNA stabilization and positive regulation of translational initiation. Located in cytoplasm. Expressed in germ line; gonad; and in male. Is an ortholog of several human genes including DAZ1 (deleted in azoospermia 1); DAZ2 (deleted in azoospermia 2); and DAZ3 (deleted in azoospermia 3). WB:WBGene00000936 dbl-1 Predicted to enable BMP receptor binding activity and cytokine activity. Involved in several processes, including defense response to other organism; positive regulation of macromolecule metabolic process; and regulation of developmental process. Predicted to be located in extracellular space. Expressed in body wall musculature; nervous system; pm2 precursor; and in male. Used to study Marfan syndrome. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); carcinoma (multiple); and eye disease (multiple). Is an ortholog of human BMP7 (bone morphogenetic protein 7). WB:WBGene00000937 dbr-1 Predicted to enable RNA lariat debranching enzyme activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in brain disease. Is an ortholog of human DBR1 (debranching RNA lariats 1). WB:WBGene00000938 dcp-66 Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in chromatin organization; mitochondrial unfolded protein response; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of NuRD complex. Expressed in neurons and tail. Human ortholog(s) of this gene implicated in GAND syndrome. Is an ortholog of human GATAD2B (GATA zinc finger domain containing 2B). WB:WBGene00000939 dcr-1 Enables deoxyribonuclease I activity and ribonuclease III activity. Involved in several processes, including nucleic acid metabolic process; olfactory learning; and positive regulation of primary miRNA processing. Acts upstream of or within defense response to Gram-positive bacterium. Located in cytosol and nucleus. Expressed in germ line; intestine; neurons; and somatic cell. Human ortholog(s) of this gene implicated in several diseases, including DICER1 syndrome; gastrointestinal system cancer (multiple); and multinodular goiter. Is an ortholog of human DICER1 (dicer 1, ribonuclease III). WB:WBGene00000940 dcs-1 Enables RNA 7-methylguanosine cap binding activity; hydrolase activity, acting on acid anhydrides; and sulfate adenylyltransferase (ADP) activity. Involved in nucleobase-containing compound metabolic process; response to heat; and sulfur compound metabolic process. Located in cytoplasm and nucleus. Is an ortholog of human DCPS (decapping enzyme, scavenger). WB:WBGene00000941 ddp-1 Predicted to enable metal ion binding activity. Involved in mitochondrion organization. Predicted to be located in mitochondrial inner membrane. Used to study deafness-dystonia-optic neuronopathy syndrome. Human ortholog(s) of this gene implicated in deafness-dystonia-optic neuronopathy syndrome and dystonia. Is an ortholog of human TIMM8A (translocase of inner mitochondrial membrane 8A). WB:WBGene00000942 deb-1 A structural constituent of cytoskeleton. Involved in positive regulation of ovulation. Located in several cellular components, including cytoskeleton; dense body; and striated muscle dense body. Expressed in gonad. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1W and hypertrophic cardiomyopathy 15. Is an ortholog of human VCL (vinculin). WB:WBGene00000943 dec-1 No description available WB:WBGene00000944 dec-2 No description available WB:WBGene00000945 dec-7 No description available WB:WBGene00000946 dec-9 No description available WB:WBGene00000947 dec-10 No description available WB:WBGene00000948 dec-11 No description available WB:WBGene00000949 dec-12 No description available WB:WBGene00000950 deg-1 Predicted to enable ligand-gated sodium channel activity. Involved in response to acidic pH and response to amino acid. Predicted to be located in membrane. Expressed in AVG; IL1 neuron; anal depressor muscle; body wall musculature; and command interneuron. Used to study hypokalemic periodic paralysis and neurodegenerative disease. Human ortholog(s) of this gene implicated in bronchiectasis (multiple) and renal tubular transport disease (multiple). Is an ortholog of human SCNN1B (sodium channel epithelial 1 subunit beta); SCNN1D (sodium channel epithelial 1 subunit delta); and SCNN1G (sodium channel epithelial 1 subunit gamma). WB:WBGene00000951 deg-3 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in positive regulation of locomotion involved in locomotory behavior and regulation of programmed cell death. Predicted to be located in neuron projection and synapse. Expressed in ALA; AVG; PVC; and mechanosensory neurons. Used to study neurodegenerative disease. WB:WBGene00000952 del-1 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Expressed in PVD; cholinergic neurons; motor neurons; and in male. Human ortholog(s) of this gene implicated in bronchiectasis (multiple) and renal tubular transport disease (multiple). Is an ortholog of human SCNN1B (sodium channel epithelial 1 subunit beta); SCNN1D (sodium channel epithelial 1 subunit delta); and SCNN1G (sodium channel epithelial 1 subunit gamma). WB:WBGene00000953 del-2 Expressed in ASEL; ASER; and neurons. WB:WBGene00000954 des-1 No description available WB:WBGene00000955 des-2 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Located in plasma membrane. Expressed in AIY; ALA; IL2 neuron; and pm1. WB:WBGene00000956 des-3 No description available WB:WBGene00000957 des-4 No description available WB:WBGene00000958 dgk-1 Enables ATP-dependent diacylglycerol kinase activity and small GTPase binding activity. Involved in several processes, including cellular response to dopamine; lipid phosphorylation; and regulation of defecation. Located in several cellular components, including axon; cell body; and perinuclear region of cytoplasm. Expressed in excretory canal; neurons; and ventral cord neurons. Is an ortholog of human DGKQ (diacylglycerol kinase theta). WB:WBGene00000959 dgk-2 Predicted to enable ATP binding activity and ATP-dependent diacylglycerol kinase activity. Predicted to be involved in lipid phosphorylation and protein kinase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in nephrotic syndrome type 7. Is an ortholog of human DGKE (diacylglycerol kinase epsilon). WB:WBGene00000960 dgk-3 Predicted to enable ATP-dependent diacylglycerol kinase activity. Involved in olfactory behavior; regulation of long-term neuronal synaptic plasticity; and thermotaxis. Predicted to be located in plasma membrane. Expressed in amphid neurons; head; and pharyngeal lumen. Is an ortholog of human DGKA (diacylglycerol kinase alpha); DGKB (diacylglycerol kinase beta); and DGKG (diacylglycerol kinase gamma). WB:WBGene00000961 dgn-1 Predicted to enable laminin binding activity. Involved in anatomical structure morphogenesis; inductive cell migration; and positive regulation of locomotion. Located in basal plasma membrane. Expressed in several structures, including ALM; PVP; e2; gonad; and lumbar ganglion. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; Fukuyama congenital muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2D; autosomal recessive limb-girdle muscular dystrophy type 2P; bronchopulmonary dysplasia; congenital muscular dystrophy-dystroglycanopathy type A9; and inclusion body myositis. Is an ortholog of human DAG1 (dystroglycan 1). WB:WBGene00000962 dhc-1 Predicted to enable minus-end-directed microtubule motor activity. Involved in several processes, including cellular localization; neuron remodeling; and regulation of cellular localization. Located in several cellular components, including kinetochore; nuclear envelope; and spindle pole. Expressed in germ cell; head; somatic cell; and tail. Used to study epilepsy and lissencephaly. Human ortholog(s) of this gene implicated in Alzheimer's disease; Charcot-Marie-Tooth disease axonal type 2O; autosomal dominant intellectual developmental disorder 13; and spinal muscular atrophy with lower extremity predominant 1. Is an ortholog of human DYNC1H1 (dynein cytoplasmic 1 heavy chain 1). WB:WBGene00000963 dhp-1 Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Involved in pyrimidine nucleobase catabolic process. Located in nucleus. Expressed in hyp7 syncytium. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome; dihydropyrimidinase deficiency; and purine-pyrimidine metabolic disorder. Is an ortholog of human DPYS (dihydropyrimidinase). WB:WBGene00000964 dhp-2 Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Involved in pyrimidine nucleobase catabolic process. Located in cytoplasm. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome; dihydropyrimidinase deficiency; and purine-pyrimidine metabolic disorder. Is an ortholog of human DPYS (dihydropyrimidinase). WB:WBGene00000965 dhs-1 Enriched in germ line and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; let-7; and gld-1 based on microarray; proteomic; and RNA-seq studies. Is affected by seven chemicals including Zidovudine; paraquat; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and short chain dehydrogenase. WB:WBGene00000966 dhs-2 Predicted to enable oxidoreductase activity. Predicted to be involved in steroid metabolic process. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 13; fundus albipunctatus; and night blindness. Is an ortholog of several human genes including HSD17B6 (hydroxysteroid 17-beta dehydrogenase 6); RDH16 (retinol dehydrogenase 16); and RDH5 (retinol dehydrogenase 5). WB:WBGene00000967 dhs-3 Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Involved in response to oxidative stress. Located in lipid droplet. Expressed in intestinal cell. Is an ortholog of human SDR16C5 (short chain dehydrogenase/reductase family 16C member 5). WB:WBGene00000968 dhs-4 Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be located in lipid droplet. Is an ortholog of human SDR16C5 (short chain dehydrogenase/reductase family 16C member 5). WB:WBGene00000969 dhs-5 Predicted to enable oxidoreductase activity. Predicted to be located in endoplasmic reticulum. Expressed in enteric muscle; hypodermis; and vm1. WB:WBGene00000970 dhs-6 Predicted to be located in mitochondrion. Is an ortholog of human HSDL2 (hydroxysteroid dehydrogenase like 2). WB:WBGene00000971 dhs-7 Predicted to be involved in regulation of reactive oxygen species metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Is an ortholog of human WWOX (WW domain containing oxidoreductase). WB:WBGene00000972 dhs-8 Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Is an ortholog of human WWOX (WW domain containing oxidoreductase). WB:WBGene00000973 dhs-9 Predicted to enable oxidoreductase activity. Expressed in head. Is an ortholog of human DHRS1 (dehydrogenase/reductase 1). WB:WBGene00000974 dhs-11 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B8 (hydroxysteroid 17-beta dehydrogenase 8). WB:WBGene00000975 dhs-12 Predicted to enable oxidoreductase activity. Predicted to be located in cytoplasm. Is an ortholog of human CBR1 (carbonyl reductase 1) and CBR3 (carbonyl reductase 3). WB:WBGene00000976 dhs-13 Predicted to enable carbonyl reductase (NADPH) activity. Is an ortholog of human DHRS2 (dehydrogenase/reductase 2); DHRS4 (dehydrogenase/reductase 4); and DHRS4L2 (dehydrogenase/reductase 4 like 2). WB:WBGene00000977 dhs-14 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00000978 dhs-15 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00000979 dhs-16 Enables steroid dehydrogenase activity. Involved in steroid catabolic process. Predicted to be located in intracellular membrane-bounded organelle. Expressed in head neurons; hypodermis; tail neurons; and terminal bulb. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 13; fundus albipunctatus; and night blindness. Is an ortholog of several human genes including DHRS9 (dehydrogenase/reductase 9); HSD17B6 (hydroxysteroid 17-beta dehydrogenase 6); and RDH5 (retinol dehydrogenase 5). WB:WBGene00000980 dhs-17 Expressed in XXXL and XXXR. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and short chain dehydrogenase. WB:WBGene00000981 dhs-18 Predicted to be located in mitochondrion. Is an ortholog of human HSDL2 (hydroxysteroid dehydrogenase like 2). WB:WBGene00000982 dhs-19 Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be located in lipid droplet. Is an ortholog of human SDR16C5 (short chain dehydrogenase/reductase family 16C member 5). WB:WBGene00000983 dhs-20 Predicted to enable oxidoreductase activity. Predicted to be involved in steroid metabolic process. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 13; fundus albipunctatus; and night blindness. Is an ortholog of several human genes including DHRS9 (dehydrogenase/reductase 9); HSD17B6 (hydroxysteroid 17-beta dehydrogenase 6); and RDH5 (retinol dehydrogenase 5). WB:WBGene00000984 dhs-21 Enables L-xylulose reductase (NADP+) activity and carbonyl reductase (NADPH) activity. Involved in xylulose catabolic process. Located in plasma membrane. Expressed in hermaphrodite gonad; hypodermis; and intestine. Human ortholog(s) of this gene implicated in pentosuria. Is an ortholog of human DCXR (dicarbonyl and L-xylulose reductase). WB:WBGene00000985 dhs-22 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 13 and Leber hereditary optic neuropathy. Is an ortholog of several human genes including RDH11 (retinol dehydrogenase 11); RDH12 (retinol dehydrogenase 12); and RDH13 (retinol dehydrogenase 13). WB:WBGene00000986 dhs-23 Predicted to enable oxidoreductase activity. Expressed in head. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00000987 dhs-24 Enriched in ABalaaaala; ABalaapaaa; and AFD based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and let-7 based on microarray; proteomic; and RNA-seq studies. Is affected by seven chemicals including rotenone; Alovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and short chain dehydrogenase. WB:WBGene00000988 dhs-25 Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Is an ortholog of human HSD17B8 (hydroxysteroid 17-beta dehydrogenase 8). WB:WBGene00000989 dhs-26 Predicted to enable oxidoreductase activity. Predicted to be located in membrane. Is an ortholog of human DHRS1 (dehydrogenase/reductase 1). WB:WBGene00000990 dhs-27 Predicted to enable oxidoreductase activity. Predicted to be located in membrane. WB:WBGene00000991 dhs-28 Predicted to enable oxidoreductase activity. Involved in several processes, including carbohydrate derivative metabolic process; dauer entry; and positive regulation of developmental process. Located in peroxisome. Expressed in hypodermis. Used to study obesity. Human ortholog(s) of this gene implicated in D-bifunctional protein deficiency; Perrault syndrome; and Stiff-Person syndrome. Is an ortholog of human HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4). WB:WBGene00000992 dhs-29 Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be located in lipid droplet. WB:WBGene00000993 dhs-30 Predicted to enable oxidoreductase activity. Predicted to be located in membrane. Is an ortholog of human DHRS7B (dehydrogenase/reductase 7B). WB:WBGene00000994 ints-6 Predicted to be involved in snRNA 3'-end processing. Predicted to be part of integrator complex. Expressed in several structures, including neurons. Is an ortholog of human INTS6 (integrator complex subunit 6) and INTS6L (integrator complex subunit 6 like). WB:WBGene00000995 die-1 Involved in neuron development involved in amphid sensory organ development and positive regulation of gene expression. Expressed in several structures, including amphid neurons; intestine; pharynx; somatic nervous system; and tail. WB:WBGene00000996 dif-1 Predicted to enable acyl carnitine transmembrane transporter activity. Involved in mitochondrial transport. Located in mitochondrial envelope. Expressed in intestine. Human ortholog(s) of this gene implicated in carnitine-acylcarnitine translocase deficiency. Is an ortholog of human SLC25A20 (solute carrier family 25 member 20). WB:WBGene00000997 dif-2 No description available WB:WBGene00000998 dig-1 Predicted to enable calcium ion binding activity. Expressed in several structures, including GLR; body wall musculature; head mesodermal cell; male sex myoblast; and non-striated muscle. WB:WBGene00000999 dig-2 No description available WB:WBGene00001000 dim-1 Predicted to be located in cytoplasm. Expressed in body wall musculature. WB:WBGene00001001 dis-3 Predicted to enable 3'-5'-RNA exonuclease activity and endonuclease activity. Predicted to be involved in rRNA catabolic process. Predicted to be located in cytoplasm and nucleolus. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is an ortholog of human DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease). WB:WBGene00001002 div-1 Predicted to enable DNA binding activity. Predicted to be involved in DNA replication initiation. Predicted to be located in nucleus. Predicted to be part of alpha DNA polymerase:primase complex. Expressed in gonad; vulva; and vulval precursor cell. Is an ortholog of human POLA2 (DNA polymerase alpha 2, accessory subunit). WB:WBGene00001003 div-2 No description available WB:WBGene00001005 dlc-1 Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in several processes, including apoptotic process; cell division; and meiotic cell cycle. Predicted to be located in cytoplasm; microtubule; and nuclear envelope. Predicted to be part of cytoplasmic dynein complex. Expressed in several structures, including germ cell; germ line; rectal valve cell; somatic cell; and ventral nerve cord. Is an ortholog of human DYNLL2 (dynein light chain LC8-type 2). WB:WBGene00001006 dlg-1 Predicted to enable guanylate kinase activity. Involved in embryo development and zonula adherens assembly. Located in adherens junction and apical junction complex. Expressed in several structures, including arcade cell; germ line; intestine; pharyngeal cell; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease; cervix uteri carcinoma in situ; intellectual disability (multiple); and invasive ductal carcinoma. Is an ortholog of human DLG1 (discs large MAGUK scaffold protein 1); DLG3 (discs large MAGUK scaffold protein 3); and DLG4 (discs large MAGUK scaffold protein 4). WB:WBGene00001007 dli-1 Predicted to enable dynein heavy chain binding activity. Involved in regulation of dendrite morphogenesis and retrograde axonal transport. Located in microtubule plus-end and neuron projection. Expressed in ciliated neurons; hypodermis; and pharynx. Is an ortholog of human DYNC1LI2 (dynein cytoplasmic 1 light intermediate chain 2). WB:WBGene00001008 dlk-1 Enables ubiquitin protein ligase binding activity. Involved in several processes, including p38MAPK cascade; regulation of axon extension; and sprouting of injured axon. Located in neuronal cell body and synapse. Expressed in PLML and PLMR. Is an ortholog of human MAP3K12 (mitogen-activated protein kinase kinase kinase 12). WB:WBGene00001009 dmo-1 No description available WB:WBGene00001010 dmo-2 No description available WB:WBGene00001011 dmo-3 No description available WB:WBGene00001012 dmo-5 No description available WB:WBGene00001013 dmo-6 No description available WB:WBGene00001014 dmo-7 No description available WB:WBGene00001015 dmo-8 No description available WB:WBGene00001016 dna-2 Enables 5'-3' DNA helicase activity; single-stranded DNA endodeoxyribonuclease activity; and single-stranded DNA helicase activity. Involved in DNA metabolic process. Located in nucleus. Expressed in gonad; oocyte; spermatheca; and uterus. Human ortholog(s) of this gene implicated in Seckel syndrome 8; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6; and isolated growth hormone deficiency type IA. Is an ortholog of human DNA2 (DNA replication helicase/nuclease 2). WB:WBGene00001017 dnc-1 Predicted to enable dynein intermediate chain binding activity and microtubule binding activity. Involved in several processes, including establishment of mitotic spindle orientation; regulation of dendrite morphogenesis; and single fertilization. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and midbody. Part of dynactin complex. Expressed in AB; P0; and Psub1. Human ortholog(s) of this gene implicated in Perry syndrome; amyotrophic lateral sclerosis type 1; and distal hereditary motor neuronopathy type 7B. Is an ortholog of human DCTN1 (dynactin subunit 1). WB:WBGene00001018 dnc-2 Involved in chromosome segregation; establishment of mitotic spindle orientation; and single fertilization. Located in cytoplasm; kinetochore; and microtubule cytoskeleton. Part of dynactin complex. Expressed in body wall musculature; neurons; seam cell; somatic nervous system; and tail. Is an ortholog of human DCTN2 (dynactin subunit 2). WB:WBGene00001019 dnj-1 Predicted to enable Hsp70 protein binding activity. Involved in protein-containing complex assembly. Located in endoplasmic reticulum membrane. Expressed in head neurons; tail neurons; and vulval muscle. Is an ortholog of human DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12) and DNAJB14 (DnaJ heat shock protein family (Hsp40) member B14). WB:WBGene00001020 dnj-2 Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human DNAJC25 (DnaJ heat shock protein family (Hsp40) member C25) and DNAJC25-GNG10 (DNAJC25-GNG10 readthrough). WB:WBGene00001021 dnj-3 Predicted to be located in membrane. WB:WBGene00001022 dnj-4 Predicted to be located in membrane. Is an ortholog of human DNAJC4 (DnaJ heat shock protein family (Hsp40) member C4). WB:WBGene00001023 dnj-5 Predicted to be located in membrane. Is an ortholog of human DNAJC14 (DnaJ heat shock protein family (Hsp40) member C14). WB:WBGene00001025 dnj-7 Predicted to enable misfolded protein binding activity; protein kinase inhibitor activity; and protein-folding chaperone binding activity. Involved in PERK-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum lumen. Expressed in head. Is an ortholog of human DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3). WB:WBGene00001026 dnj-8 Predicted to be involved in autophagy. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human DNAJC16 (DnaJ heat shock protein family (Hsp40) member C16). WB:WBGene00001027 dnj-9 Predicted to be involved in cristae formation. Predicted to be located in mitochondrion. Is an ortholog of human DNAJC11 (DnaJ heat shock protein family (Hsp40) member C11). WB:WBGene00001028 dnj-10 Predicted to enable unfolded protein binding activity. Involved in embryo development and nematode larval development. Predicted to be located in mitochondrion. Expressed in head and tail. Is an ortholog of human DNAJA3 (DnaJ heat shock protein family (Hsp40) member A3). WB:WBGene00001029 dnj-11 Predicted to enable Hsp70 protein binding activity and ribosome binding activity. Predicted to be involved in 'de novo' cotranslational protein folding. Located in cytosol. Expressed in several structures, including head; muscle cell; neurons; and tail. Is an ortholog of human DNAJC2 (DnaJ heat shock protein family (Hsp40) member C2). WB:WBGene00001030 dnj-12 Enables ATPase activator activity. Predicted to be involved in protein refolding. Predicted to be located in cytosol. Is an ortholog of human DNAJA1 (DnaJ heat shock protein family (Hsp40) member A1) and DNAJA4 (DnaJ heat shock protein family (Hsp40) member A4). WB:WBGene00001031 dnj-13 Enables ATPase activator activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in congenital myopathy 21. Is an ortholog of human DNAJB5 (DnaJ heat shock protein family (Hsp40) member B5). WB:WBGene00001032 dnj-14 Involved in determination of adult lifespan; locomotion; and neurotransmitter secretion. Predicted to be located in type Is terminal bouton. Used to study neuronal ceroid lipofuscinosis. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 4. Is an ortholog of human DNAJC5 (DnaJ heat shock protein family (Hsp40) member C5) and DNAJC5B (DnaJ heat shock protein family (Hsp40) member C5 beta). WB:WBGene00001033 dnj-15 Predicted to enable ATPase activator activity and protein-folding chaperone binding activity. Predicted to be involved in [2Fe-2S] cluster assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in sideroblastic anemia. Is an ortholog of human HSCB (HscB mitochondrial iron-sulfur cluster cochaperone). WB:WBGene00001034 dnj-16 Enriched in several structures, including ABplapaaapa; ABprapaaapa; germ line; intestine; and neurons based on RNA-seq; tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by nine chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: DnaJ domain and Chaperone J-domain superfamily. WB:WBGene00001035 dnj-17 Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be located in cytoplasm. Expressed in head neurons. Is an ortholog of human DNAJC21 (DnaJ heat shock protein family (Hsp40) member C21). WB:WBGene00001036 dnj-18 Predicted to be involved in mitochondrion organization and negative regulation of apoptotic process. Predicted to be located in mitochondrion. WB:WBGene00001037 dnj-19 Predicted to enable protein-folding chaperone binding activity. Involved in response to topologically incorrect protein. Predicted to be located in cytosol. Is an ortholog of human DNAJA2 (DnaJ heat shock protein family (Hsp40) member A2). WB:WBGene00001038 dnj-20 Predicted to enable misfolded protein binding activity and unfolded protein binding activity. Predicted to be involved in protein maturation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in polycystic kidney disease. Is an ortholog of human DNAJB11 (DnaJ heat shock protein family (Hsp40) member B11). WB:WBGene00001039 dnj-21 Predicted to enable ATPase activator activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 5. Is an ortholog of human DNAJC19 (DnaJ heat shock protein family (Hsp40) member C19). WB:WBGene00001040 dnj-22 Predicted to be involved in spliceosomal complex disassembly. Predicted to be part of spliceosomal complex. Is an ortholog of human DNAJC17 (DnaJ heat shock protein family (Hsp40) member C17). WB:WBGene00001041 dnj-23 Predicted to enable heat shock protein binding activity. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human DNAJC9 (DnaJ heat shock protein family (Hsp40) member C9). WB:WBGene00001042 dnj-24 Predicted to enable protein folding chaperone; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in chaperone-mediated protein folding. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 1 and distal spinal muscular atrophy type 5. Is an ortholog of human DNAJB8 (DnaJ heat shock protein family (Hsp40) member B8). WB:WBGene00001043 dnj-25 Predicted to enable clathrin binding activity. Involved in receptor-mediated endocytosis. Predicted to be located in cytoplasm; intracellular membrane-bounded organelle; and vesicle. Human ortholog(s) of this gene implicated in Parkinson's disease 19A. Is an ortholog of human DNAJC6 (DnaJ heat shock protein family (Hsp40) member C6). WB:WBGene00001044 dnj-26 Predicted to enable Hsp70 protein binding activity. Predicted to be involved in cellular response to misfolded protein and chaperone cofactor-dependent protein refolding. Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00001045 dnj-27 Predicted to enable misfolded protein binding activity; oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; and protein-disulfide reductase activity. Involved in IRE1-mediated unfolded protein response. Located in endoplasmic reticulum lumen. Expressed in several structures, including body wall musculature; gonadal sheath cell; intestine; rectum; and vulva. Is an ortholog of human DNAJC10 (DnaJ heat shock protein family (Hsp40) member C10). WB:WBGene00001046 dnj-28 Predicted to enable misfolded protein binding activity and protein-folding chaperone binding activity. Acts upstream of or within PERK-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum. Expressed in head and tail. Is an ortholog of human DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3). WB:WBGene00001047 dnj-29 Predicted to enable protein transmembrane transporter activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane and post-translational protein targeting to endoplasmic reticulum membrane. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of Sec62/Sec63 complex. Human ortholog(s) of this gene implicated in polycystic liver disease. Is an ortholog of human SEC63 (SEC63 homolog, protein translocation regulator). WB:WBGene00001048 dnj-30 Predicted to be located in nucleus. Is an ortholog of human DNAJC8 (DnaJ heat shock protein family (Hsp40) member C8). WB:WBGene00001049 dog-1 Predicted to enable DNA helicase activity. Involved in DNA metabolic process; regulation of DNA-templated DNA replication; and reproduction. Predicted to be located in nucleus. Expressed in head and tail. Used to study Fanconi anemia. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; Fanconi anemia complementation group J; and cervical squamous cell carcinoma. Is an ortholog of human BRIP1 (BRCA1 interacting helicase 1). WB:WBGene00001050 dom-3 Predicted to enable mRNA 5'-diphosphatase activity. Predicted to be involved in NAD-cap decapping; nuclear-transcribed mRNA catabolic process; and nucleic acid phosphodiester bond hydrolysis. Predicted to be located in cytosol and nucleus. Is an ortholog of human DXO (decapping exoribonuclease). WB:WBGene00001051 cks-1 Enables protein kinase binding activity. Involved in regulation of mitotic cell cycle, embryonic. Predicted to be located in nucleus. Predicted to be part of SCF ubiquitin ligase complex and cyclin-dependent protein kinase holoenzyme complex. Is an ortholog of human CKS1B (CDC28 protein kinase regulatory subunit 1B). WB:WBGene00001052 dop-1 Enables dopamine neurotransmitter receptor activity, coupled via Gs; epinephrine binding activity; and norepinephrine binding activity. Involved in several processes, including adenylate cyclase-activating dopamine receptor signaling pathway; habituation; and mechanosensory behavior. Predicted to be located in dendrite. Expressed in several structures, including accessory cell; excretory gland cell; head muscle; mechanosensory neurons; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; attention deficit hyperactivity disorder; blepharospasm; and kidney failure. Is an ortholog of human DRD1 (dopamine receptor D1). WB:WBGene00001053 dop-2 Enables dopamine neurotransmitter receptor activity, coupled via Gi/Go. Involved in several processes, including cellular response to organonitrogen compound; male mating behavior; and regulation of locomotion involved in locomotory behavior. Predicted to be located in dendrite. Expressed in GLR; male-specific anatomical entity; and neurons. Used to study Parkinson's disease and nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; end stage renal disease; essential tremor 1; and type 2 diabetes mellitus. Is an ortholog of human DRD3 (dopamine receptor D3). WB:WBGene00001054 dpf-1 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Middle East respiratory syndrome; autosomal dominant intellectual developmental disorder 33; and motor neuron disease (multiple). Is an ortholog of human DPP6 (dipeptidyl peptidase like 6). WB:WBGene00001055 dpf-2 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in plasma membrane. Expressed in head. Human ortholog(s) of this gene implicated in Middle East respiratory syndrome; squamous cell carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human FAP (fibroblast activation protein alpha). WB:WBGene00001056 dpf-3 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human DPP8 (dipeptidyl peptidase 8) and DPP9 (dipeptidyl peptidase 9). WB:WBGene00001057 dpf-4 Predicted to enable serine-type peptidase activity. Predicted to be involved in proteolysis. Located in nucleus. WB:WBGene00001058 dpf-5 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human APEH (acylaminoacyl-peptide hydrolase). WB:WBGene00001059 dpf-6 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in plasma membrane. WB:WBGene00001060 dpf-7 Predicted to enable serine-type endopeptidase activity. WB:WBGene00001061 dpl-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including negative regulation of Ras protein signal transduction; negative regulation of vulval development; and regulation of cell cycle. Located in nucleus. Expressed in germ line; gonad; and hyp7 syncytium. Human ortholog(s) of this gene implicated in mismatch repair cancer syndrome. Is an ortholog of human TFDP1 (transcription factor Dp-1); TFDP2 (transcription factor Dp-2); and TFDP3 (transcription factor Dp family member 3). WB:WBGene00001062 dpr-1 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00001063 dpy-1 Involved in body morphogenesis and regulation of growth. Predicted to be located in membrane. WB:WBGene00001064 dpy-2 Predicted to be a structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle; post-embryonic body morphogenesis; and regulation of growth. Predicted to be part of collagen trimer. Expressed in head neurons and pharynx. Used to study skin disease. WB:WBGene00001065 dpy-3 Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Used to study skin disease. Is an ortholog of human C1QTNF9 (C1q and TNF related 9); C1QTNF9B (C1q and TNF related 9B); and OTOL1 (otolin 1). WB:WBGene00001066 dpy-4 Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); brain small vessel disease 2; and multiple epiphyseal dysplasia 6. Is an ortholog of human COL27A1 (collagen type XXVII alpha 1 chain); COL4A2 (collagen type IV alpha 2 chain); and COL9A1 (collagen type IX alpha 1 chain). WB:WBGene00001067 dpy-5 A structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and post-embryonic body morphogenesis. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in hypodermis. WB:WBGene00001068 dpy-6 Enables calmodulin binding activity. WB:WBGene00001069 dpy-7 A structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and post-embryonic body morphogenesis. Located in annular furrow extracellular matrix. Expressed in several structures, including P1; P12; P2; cuticle; and hypodermis. Used to study skin disease. WB:WBGene00001070 dpy-8 Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Used to study skin disease. WB:WBGene00001071 dpy-9 Predicted to be a structural constituent of cuticle. Involved in regulation of gene expression. Predicted to be located in membrane. Predicted to be part of collagen trimer. Used to study skin disease. WB:WBGene00001072 dpy-10 Predicted to be a structural constituent of collagen and cuticulin-based cuticle. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; locomotion; and post-embryonic body morphogenesis. Predicted to be part of collagen trimer. Used to study skin disease. WB:WBGene00001073 dpy-11 Enables protein-disulfide reductase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; post-embryonic body morphogenesis; and protein folding. Located in endomembrane system. Expressed in several structures, including R1_hyp; R2_hyp; R3_hyp; R4_hyp; and R5_hyp. Is an ortholog of human TMX1 (thioredoxin related transmembrane protein 1). WB:WBGene00001074 dpy-13 Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in collagen and cuticulin-based cuticle extracellular matrix. WB:WBGene00001075 dpy-14 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. Expressed in anterior ganglion; hyp7 syncytium; and lateral ganglion left neurons. WB:WBGene00001076 dpy-17 Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be part of collagen trimer. Used to study Marfan syndrome. WB:WBGene00001077 dpy-18 Enables procollagen-proline 4-dioxygenase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; embryo development; and embryonic body morphogenesis. Located in endoplasmic reticulum. Expressed in hypodermis; muscle cell; neurons; and pharynx. Human ortholog(s) of this gene implicated in myopia. Is an ortholog of human P4HA1 (prolyl 4-hydroxylase subunit alpha 1) and P4HA2 (prolyl 4-hydroxylase subunit alpha 2). WB:WBGene00001078 dpy-19 Enables mannosyltransferase activity. Predicted to be involved in carbohydrate metabolic process; cell differentiation; and nervous system development. Located in perinuclear region of cytoplasm. Expressed in several structures, including P1; P2; QL; QR; and seam cell. Human ortholog(s) of this gene implicated in spermatogenic failure 9. Is an ortholog of human DPY19L2 (dpy-19 like 2). WB:WBGene00001079 dpy-20 Enables sequence-specific double-stranded DNA binding activity. WB:WBGene00001080 dpy-21 Enables histone H4K20 demethylase activity. Predicted to be involved in chromatin remodeling. Located in X chromosome. Is an ortholog of human RSBN1L (round spermatid basic protein 1 like). WB:WBGene00001081 dpy-22 Predicted to enable transcription coactivator activity. Involved in negative regulation of epidermal growth factor receptor signaling pathway and negative regulation of vulval development. Located in nucleus. Expressed in several structures, including hypodermal cell; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in several diseases, including X-linked recessive disease (multiple); major depressive disorder; and phobic disorder. Is an ortholog of human MED12L (mediator complex subunit 12L). WB:WBGene00001082 dpy-23 Predicted to enable clathrin adaptor activity. Involved in several processes, including necroptotic process; positive regulation of Wnt protein secretion; and protein localization to non-motile cilium. Located in periciliary membrane compartment and synaptic vesicle. Expressed in anal depressor muscle; germ line; neurons; rectal epithelial cell; and spermatheca. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Is an ortholog of human AP2M1 (adaptor related protein complex 2 subunit mu 1). WB:WBGene00001084 dpy-25 No description available WB:WBGene00001085 dpy-26 Involved in dosage compensation by hypoactivation of X chromosome; meiotic sister chromatid segregation; and mitotic sister chromatid segregation. Located in condensed nuclear chromosome. Part of dosage compensation complex. Expressed widely. WB:WBGene00001086 dpy-27 Enables sequence-specific DNA binding activity. Involved in dosage compensation by hypoactivation of X chromosome. Located in X chromosome and nuclear chromosome. Part of dosage compensation complex. Is an ortholog of human SMC4 (structural maintenance of chromosomes 4). WB:WBGene00001087 dpy-28 Predicted to enable histone binding activity. Involved in meiotic sister chromatid segregation; mitotic sister chromatid segregation; and negative regulation of reciprocal meiotic recombination. Located in X chromosome and nucleus. Part of dosage compensation complex. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Is an ortholog of human NCAPD2 (non-SMC condensin I complex subunit D2). WB:WBGene00001088 dpy-30 Involved in several processes, including dosage compensation by hypoactivation of X chromosome; nematode male tail tip morphogenesis; and transdifferentiation. Located in nucleus. Is an ortholog of human DPY30 (dpy-30 histone methyltransferase complex regulatory subunit). WB:WBGene00001089 dre-1 Predicted to enable zinc ion binding activity. Involved in several processes, including mesodermal cell migration; nematode larval development; and positive regulation of apoptotic process involved in development. Located in cytoplasm and nucleus. Expressed in several structures, including P5.ppp; gonad; hypodermis; non-striated muscle; and vulva. Human ortholog(s) of this gene implicated in breast carcinoma; gastrointestinal system cancer (multiple); and lung non-small cell carcinoma. Is an ortholog of human FBXO11 (F-box protein 11). WB:WBGene00001090 drh-1 Predicted to enable several functions, including ATP binding activity; DNA binding activity; and helicase activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome and primary immunodeficiency disease. Is an ortholog of human RIGI (RNA sensor RIG-I). WB:WBGene00001091 drh-2 Enriched in intestine; muscle cell; and neurons based on microarray and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and rrf-3 based on proteomic; microarray; and RNA-seq studies. Is affected by twelve chemicals including rotenone; levamisole; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00001092 dro-1 Predicted to enable RNA polymerase II general transcription initiation factor activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be part of negative cofactor 2 complex. Is an ortholog of human DR1 (down-regulator of transcription 1). WB:WBGene00001093 drp-1 Predicted to enable GTP binding activity; GTPase activity; and microtubule binding activity. Involved in apoptotic mitochondrial changes; embryo development; and mitochondrial fission. Located in mitochondrion. Expressed in several structures, including germ line; non-striated muscle; preanal ganglion; rectal muscle; and somatic nervous system. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; encephalopathy due to defective mitochondrial and peroxisomal fission 1; optic atrophy 5; and pulmonary fibrosis. Is an ortholog of human DNM1L (dynamin 1 like). WB:WBGene00001094 dars-1 Predicted to enable RNA binding activity and aspartate-tRNA ligase activity. Predicted to be involved in aspartyl-tRNA aminoacylation. Predicted to be located in cytosol. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Is an ortholog of human DARS1 (aspartyl-tRNA synthetase 1). WB:WBGene00001095 dars-2 Predicted to enable aspartate-tRNA ligase activity. Predicted to be involved in aspartyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Is an ortholog of human DARS2 (aspartyl-tRNA synthetase 2, mitochondrial). WB:WBGene00001096 dsc-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of defecation rhythm and regulation of DNA-templated transcription. Located in cell projection; cytoplasm; and nucleus. Expressed in amphid neurons; enteric muscle; and mechanosensory neurons. Human ortholog(s) of this gene implicated in several diseases, including frontonasal dysplasia 1; frontonasal dysplasia 2; and gastrointestinal system cancer (multiple). Is an ortholog of human ALX1 (ALX homeobox 1); ALX3 (ALX homeobox 3); and ALX4 (ALX homeobox 4). WB:WBGene00001097 dsc-2 No description available WB:WBGene00001098 dsc-3 No description available WB:WBGene00001099 dsc-4 Predicted to enable lipid transfer activity and phospholipid transporter activity. Involved in lipoprotein transport and plasma lipoprotein particle assembly. Located in endoplasmic reticulum. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including abetalipoproteinemia; familial hypercholesterolemia; and hyperinsulinism. Is an ortholog of human MTTP (microsomal triglyceride transfer protein). WB:WBGene00001100 dsc-5 No description available WB:WBGene00001101 dsh-1 Enables receptor tyrosine kinase binding activity. Involved in Wnt signaling pathway, regulating spindle positioning. Predicted to be located in cytosol. Expressed in several structures, including germ line; gonad; neurons; tail; and vulva. Human ortholog(s) of this gene implicated in DiGeorge syndrome and autosomal dominant Robinow syndrome 2. Is an ortholog of human DVL1 (dishevelled segment polarity protein 1). WB:WBGene00001102 dsh-2 Predicted to enable frizzled binding activity. Involved in several processes, including Wnt signaling pathway, regulating spindle positioning; embryonic morphogenesis; and left/right axis specification. Located in cell cortex. Expressed in several structures, including QL; QR; distal tip cell; midbody; and somatic gonad precursor. Human ortholog(s) of this gene implicated in DiGeorge syndrome; Robinow syndrome (multiple); and lung cancer. Is an ortholog of human DVL1 (dishevelled segment polarity protein 1). WB:WBGene00001103 dsl-1 Enables Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in extracellular region and membrane. Expressed in several structures, including P6.paa; P6.pap; P6.ppa; P6.ppp; and vulval cell. WB:WBGene00001104 dsl-2 Predicted to enable Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in membrane. Expressed in head and tail. WB:WBGene00001105 dsl-3 Predicted to enable Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in membrane. WB:WBGene00001106 dsl-4 Predicted to enable Notch binding activity. Predicted to be involved in cell communication. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Adams-Oliver syndrome; limb ischemia; and temporal arteritis. Is an ortholog of human DLL1 (delta like canonical Notch ligand 1) and DLL4 (delta like canonical Notch ligand 4). WB:WBGene00001107 dsl-5 Predicted to enable Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in membrane. WB:WBGene00001108 dsl-6 Predicted to enable Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in membrane. WB:WBGene00001109 dsl-7 Predicted to enable Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in membrane. WB:WBGene00001110 duo-1 Predicted to enable cysteine-type deubiquitinase activity. Is an ortholog of human OTUD1 (OTU deubiquitinase 1). WB:WBGene00001111 duo-2 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including mex-1; smg-2; and let-418 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; multi-walled carbon nanotube; and metformin based on microarray and RNA-seq studies. WB:WBGene00001112 duo-3 Predicted to enable cysteine-type deubiquitinase activity. Is an ortholog of human USP29 (ubiquitin specific peptidase 29). WB:WBGene00001113 dur-1 Enriched in body wall musculature; cephalic sheath cell; germ line; muscle cell; and sensory neurons based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on proteomic; microarray; and RNA-seq studies. Is affected by twenty-five chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq; microarray; and proteomic studies. WB:WBGene00001114 dur-91 No description available WB:WBGene00001115 dyb-1 Enables acetylcholine transmembrane transporter activity and cytoskeletal protein binding activity. Involved in several processes, including muscle cell cellular homeostasis; positive regulation of cholinergic synaptic transmission; and sarcomere organization. Located in plasma membrane. Part of dystrobrevin complex. Expressed in body wall musculature; non-striated muscle; somatic nervous system; and tail neurons. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in left ventricular noncompaction. Is an ortholog of human DTNA (dystrobrevin alpha). WB:WBGene00001116 dyc-1 A structural constituent of muscle. Involved in several processes, including muscle cell cellular homeostasis; regulation of egg-laying behavior; and sarcomere organization. Located in axon and striated muscle dense body. Part of dystrophin-associated glycoprotein complex. Expressed in SDQL; SDQR; body wall musculature; head neurons; and vulval muscle. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in nephrotic syndrome type 22. Is an ortholog of human NOS1AP (nitric oxide synthase 1 adaptor protein). WB:WBGene00001117 dyf-1 Predicted to enable intraciliary transport particle B binding activity. Involved in intraciliary transport and protein localization to plasma membrane. Located in axonemal microtubule and ciliary basal body. Expressed in amphid neurons; inner labial neurons; outer labial neurons; and phasmid neurons. Is an ortholog of human IFT70A (intraflagellar transport 70A) and IFT70B (intraflagellar transport 70B). WB:WBGene00001118 dyf-2 Involved in several processes, including chemotaxis; cilium organization; and olfactory behavior. Acts upstream of or within cilium assembly and intraciliary retrograde transport. Located in non-motile cilium. Part of intraciliary transport particle B. Expressed in neurons and oxygen sensory neurons. Human ortholog(s) of this gene implicated in several diseases, including Caroli disease; Senior-Loken syndrome; and asphyxiating thoracic dystrophy 5. Is an ortholog of human WDR19 (WD repeat domain 19). WB:WBGene00001119 dyf-3 Involved in several processes, including chemosensory behavior; cilium assembly; and response to alkaline pH. Located in axon; dendrite; and neuronal cell body. Expressed in neurons. Is an ortholog of human CLUAP1 (clusterin associated protein 1). WB:WBGene00001121 dyf-5 Predicted to enable ATP binding activity and MAP kinase activity. Involved in cilium organization; protein localization; and regulation of non-motile cilium assembly. Located in neuronal cell body and plasma membrane bounded cell projection. Expressed in lateral ganglion and neurons. Human ortholog(s) of this gene implicated in endocrine-cerebro-osteodysplasia syndrome; juvenile myoclonic epilepsy 10; and retinitis pigmentosa 62. Is an ortholog of human MAK (male germ cell associated kinase). WB:WBGene00001122 dyf-6 Involved in intraciliary transport and non-motile cilium assembly. Located in dendrite and neuronal cell body. Expressed in ciliated neurons and hypodermis. Is an ortholog of human IFT46 (intraflagellar transport 46). WB:WBGene00001123 dyf-7 Enables protein self-association. Involved in amphid sensory organ dendrite retrograde extension and neuron projection extension. Located in dendrite membrane. WB:WBGene00001125 dyf-9 No description available WB:WBGene00001126 dyf-10 No description available WB:WBGene00001127 dyf-11 Predicted to enable microtubule binding activity. Involved in several processes, including cilium organization; dauer entry; and hyperosmotic response. Located in axoneme and ciliary basal body. Part of intraciliary transport particle B. Expressed in ciliated neurons and sensory neurons. Human ortholog(s) of this gene implicated in Senior-Loken syndrome. Is an ortholog of human TRAF3IP1 (TRAF3 interacting protein 1). WB:WBGene00001128 dyf-12 No description available WB:WBGene00001129 dyf-13 Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in intraciliary anterograde transport and intraciliary transport involved in cilium assembly. Predicted to be located in ciliary basal body and ciliary base. Predicted to be part of intraciliary transport particle B. Expressed in neurons. Is an ortholog of human IFT56 (intraflagellar transport 56). WB:WBGene00001130 dyn-1 Enables GTPase activity. Involved in several processes, including embryo development; endocytosis; and necroptotic process. Located in several cellular components, including plasma membrane; plasma membrane bounded cell projection; and spindle microtubule. Expressed in several structures, including neurons; non-striated muscle; pharyngeal-intestinal valve; rectal valve cell; and somatic nervous system. Used to study early infantile epileptic encephalopathy. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Charcot-Marie-Tooth disease dominant intermediate B; centronuclear myopathy 1; and developmental and epileptic encephalopathy (multiple). Is an ortholog of human DNM1 (dynamin 1); DNM2 (dynamin 2); and DNM3 (dynamin 3). WB:WBGene00001131 dys-1 Predicted to enable actin binding activity and zinc ion binding activity. Involved in several processes, including forward locomotion; muscle cell cellular homeostasis; and sarcomere organization. Located in striated muscle dense body. Part of dystrobrevin complex. Expressed in body wall musculature; head muscle; pharyngeal muscle cell; and vulval muscle. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in several diseases, including Becker muscular dystrophy; Duchenne muscular dystrophy; cognitive disorder; dilated cardiomyopathy (multiple); and ovarian cancer. Is an ortholog of human DMD (dystrophin) and UTRN (utrophin). WB:WBGene00001132 alp-1 Predicted to enable actin binding activity and muscle alpha-actinin binding activity. Involved in determination of adult lifespan and pharyngeal pumping. Located in several cellular components, including actin filament bundle; basal part of cell; and striated muscle dense body. Expressed in body wall musculature; hypodermis; marginal cell; and pharyngeal muscle cell. Used to study cardiomyopathy and myopathy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1C; distal myopathy; myofibrillar myopathy 4; and myotonic dystrophy type 1. Is an ortholog of human PDLIM5 (PDZ and LIM domain 5). WB:WBGene00001133 eat-2 Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in several processes, including feeding behavior; positive regulation of multicellular organismal process; and regulation of eating behavior. Located in neuromuscular junction and plasma membrane. Part of acetylcholine-gated channel complex. Expressed in pm4 and pm5. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). WB:WBGene00001134 eat-3 Predicted to enable GTPase activity and microtubule binding activity. Involved in several processes, including mitochondrial fusion; nematode larval development; and response to superoxide. Located in mitochondrion. Expressed in intestinal cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Behr syndrome; dominant optic atrophy plus syndrome; and mitochondrial DNA depletion syndrome 14. Is an ortholog of human OPA1 (OPA1 mitochondrial dynamin like GTPase). WB:WBGene00001135 eat-4 Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neurotransmitter transmembrane transporter activity. Involved in several processes, including glutamatergic synaptic transmission; positive regulation of backward locomotion; and regulation of male mating behavior. Predicted to be located in excitatory synapse and synaptic vesicle membrane. Expressed in intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Is an ortholog of human SLC17A7 (solute carrier family 17 member 7) and SLC17A8 (solute carrier family 17 member 8). WB:WBGene00001136 eat-5 Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in gap junction and plasma membrane. Expressed in K' cell and pharynx. WB:WBGene00001137 eat-6 Enables P-type sodium:potassium-exchanging transporter activity. Involved in several processes, including action potential; monoatomic ion transport; and regulation of muscle contraction. Located in membrane. Expressed in several structures, including coelomocyte; intestine; neurons; pharynx; and vulval muscle. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2DD; alternating hemiplegia of childhood; and brain disease (multiple). Is an ortholog of human ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3). WB:WBGene00001139 eat-8 No description available WB:WBGene00001140 eat-9 No description available WB:WBGene00001141 eat-10 No description available WB:WBGene00001142 eat-13 No description available WB:WBGene00001143 eat-14 No description available WB:WBGene00001144 eat-15 No description available WB:WBGene00001145 eat-16 Enables GTPase activator activity. Involved in several processes, including phospholipase C-inhibiting G protein-coupled receptor signaling pathway; regulation of cell communication; and response to monoamine. Located in cytoplasm; neuron projection; and plasma membrane. Expressed in HSNL; HSNR; neurons; pharyngeal muscle cell; and vulval muscle. Human ortholog(s) of this gene implicated in bradyopsia 1. Is an ortholog of human RGS9 (regulator of G protein signaling 9). WB:WBGene00001147 eat-18 Involved in chemical synaptic transmission and regulation of pharyngeal pumping. Predicted to be located in membrane. WB:WBGene00001148 eat-20 Predicted to enable calcium ion binding activity. Located in axon and cell surface. Expressed in several structures, including anterior ganglion (post); coelomocyte; pharynx; ray neurons; and somatic nervous system. WB:WBGene00001149 bcat-1 Predicted to enable branched-chain-amino-acid transaminase activity. Involved in branched-chain amino acid catabolic process; embryo development; and nematode larval development. Acts upstream of or within determination of adult lifespan. Located in mitochondrion. Is an ortholog of human BCAT2 (branched chain amino acid transaminase 2). WB:WBGene00001150 ech-1.1 Predicted to enable enoyl-CoA hydratase activity and long-chain-3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial fatty acid beta-oxidation multienzyme complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; fatty liver disease; and mitochondrial trifunctional protein deficiency. Is an ortholog of human HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha). WB:WBGene00001151 ech-2 Predicted to enable hydro-lyase activity. Predicted to be located in mitochondrion. Is an ortholog of human ECHDC3 (enoyl-CoA hydratase domain containing 3). WB:WBGene00001152 ech-3 Involved in IRE1-mediated unfolded protein response. WB:WBGene00001153 ech-4 Predicted to enable fatty-acyl-CoA binding activity. Involved in fatty acid beta-oxidation and lipid storage. Expressed in hypodermis. Is an ortholog of human ECI2 (enoyl-CoA delta isomerase 2). WB:WBGene00001154 ech-5 Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 1 and renal tubular transport disease. Is an ortholog of human AUH (AU RNA binding methylglutaconyl-CoA hydratase) and ECHDC2 (enoyl-CoA hydratase domain containing 2). WB:WBGene00001155 ech-6 Predicted to enable enoyl-CoA hydratase activity. Predicted to be involved in fatty acid beta-oxidation. Located in mitochondrion. Is an ortholog of human ECHS1 (enoyl-CoA hydratase, short chain 1). WB:WBGene00001156 ech-7 Predicted to enable enoyl-CoA hydratase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Is an ortholog of human ECHS1 (enoyl-CoA hydratase, short chain 1). WB:WBGene00001157 ech-8 Predicted to enable 3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in Fanconi renotubular syndrome 3. Is an ortholog of human EHHADH (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase). WB:WBGene00001158 ech-9 Predicted to enable 3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in Fanconi renotubular syndrome 3. Is an ortholog of human EHHADH (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase). WB:WBGene00001159 eff-1 Enables fusogenic activity and identical protein binding activity. Involved in several processes, including anatomical structure morphogenesis; egg-laying behavior; and pharyngeal muscle development. Located in cell-cell contact zone; cytoplasm; and plasma membrane. Expressed in several structures, including P3.pa; P3.pp; hypodermis; tail spike; and vulval cell. WB:WBGene00001160 efk-1 Enables elongation factor-2 kinase activity. Predicted to be involved in myosin II filament disassembly. Human ortholog(s) of this gene implicated in Alzheimer's disease and lung adenocarcinoma. Is an ortholog of human EEF2K (eukaryotic elongation factor 2 kinase). WB:WBGene00001161 efl-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including embryonic digestive tract morphogenesis; negative regulation of Ras protein signal transduction; and negative regulation of vulval development. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Expressed in gonad. Human ortholog(s) of this gene implicated in Lynch syndrome and prostate carcinoma. Is an ortholog of human E2F4 (E2F transcription factor 4). WB:WBGene00001162 efl-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Expressed in dorsal nerve cord; head muscle; intestine; spermatheca; and ventral nerve cord. Is an ortholog of human E2F6 (E2F transcription factor 6). WB:WBGene00001163 efn-2 Predicted to enable ephrin receptor binding activity. Predicted to be involved in axon guidance and ephrin receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in several structures, including excretory gland cell; head neurons; motor neurons; pharyngeal muscle cell; and retrovesicular ganglion neurons. Human ortholog(s) of this gene implicated in several diseases, including craniofrontonasal syndrome; gastrointestinal system cancer (multiple); and varicose veins. Is an ortholog of human EFNB1 (ephrin B1) and EFNB3 (ephrin B3). WB:WBGene00001164 efn-3 Predicted to enable ephrin receptor binding activity. Predicted to be involved in axon guidance and ephrin receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome; dysostosis; and stomach cancer. Is an ortholog of human EFNB1 (ephrin B1). WB:WBGene00001165 efn-4 Predicted to enable ephrin receptor binding activity. Involved in several processes, including embryonic morphogenesis; nematode male tail tip morphogenesis; and regulation of axon guidance. Located in axon and neuronal cell body. Expressed in several structures, including CAN; epithelial cell; ganglia; intestinal cell; and somatic nervous system. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome; dysostosis; and stomach cancer. Is an ortholog of human EFNB1 (ephrin B1). WB:WBGene00001166 eftu-2 Predicted to enable GTPase activity and U5 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol. Predicted to be part of U2-type catalytic step 2 spliceosome and U4/U6 x U5 tri-snRNP complex. Human ortholog(s) of this gene implicated in several diseases, including esophageal atresia; hepatitis B; and mandibulofacial dysostosis, Guion-Almeida type. Is an ortholog of human EFTUD2 (elongation factor Tu GTP binding domain containing 2). WB:WBGene00001167 eef-2 Predicted to enable GTPase activity; ribosome binding activity; and translation elongation factor activity. Involved in defense response to Gram-negative bacterium and negative regulation of gene expression. Predicted to be located in cytosol. Predicted to be part of ribonucleoprotein complex. Expressed in several structures, including germ line. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; brain glioblastoma multiforme; carcinoma (multiple); and spinocerebellar ataxia type 26. Is an ortholog of human EEF2 (eukaryotic translation elongation factor 2). WB:WBGene00001168 eef-1A.1 Enables GTPase activity. Predicted to be involved in translational elongation. Predicted to be located in cytoplasm. Expressed in hypodermis; intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant intellectual developmental disorder 38; developmental and epileptic encephalopathy 33; and ovarian cancer. Is an ortholog of human EEF1A1 (eukaryotic translation elongation factor 1 alpha 1); EEF1A1P5 (eukaryotic translation elongation factor 1 alpha 1 pseudogene 5); and EEF1A2 (eukaryotic translation elongation factor 1 alpha 2). WB:WBGene00001169 eef-1A.2 Predicted to enable GTP binding activity; GTPase activity; and translation elongation factor activity. Predicted to be involved in translational elongation. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant intellectual developmental disorder 38; developmental and epileptic encephalopathy 33; and ovarian cancer. Is an ortholog of human EEF1A1 (eukaryotic translation elongation factor 1 alpha 1); EEF1A1P5 (eukaryotic translation elongation factor 1 alpha 1 pseudogene 5); and EEF1A2 (eukaryotic translation elongation factor 1 alpha 2). WB:WBGene00001170 egl-1 Involved in several processes, including actin filament depolymerization; apoptotic process; and positive regulation of cellular component organization. Located in cytosol; mitochondrion; and presynapse. Expressed in several structures, including ABalappaapp; ABaraapapaad; HSN; URX; and proctodeal cell. WB:WBGene00001171 egl-2 Enables protein kinase binding activity. Involved in chemosensory behavior; egg-laying behavior; and muscle contraction. Located in microvillus membrane. Expressed in several structures, including intestinal cell; lumbar neurons; sensory neurons; vulval muscle; and in male. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma; hepatocellular carcinoma; and renal cell carcinoma. Is an ortholog of human KCNH5 (potassium voltage-gated channel subfamily H member 5). WB:WBGene00001172 egl-3 Enables FBXO family protein binding activity and serine-type endopeptidase activity. Involved in several processes, including modulation of chemical synaptic transmission; protein processing; and regulation of multicellular organismal process. Located in axon. Expressed in several structures, including mechanosensory neurons; nerve ring; pharynx; tail; and uv1. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in myocardial infarction and type 2 diabetes mellitus. Is an ortholog of human PCSK2 (proprotein convertase subtilisin/kexin type 2). WB:WBGene00001173 egl-4 Enables cGMP-dependent protein kinase activity. Involved in several processes, including regulation of multicellular organismal process; regulation of signal transduction; and response to oxygen-containing compound. Located in cytosol and nucleus. Expressed in several structures, including marginal cell; nerve ring; neurons; spermatheca; and vulval muscle. Used to study ciliopathy. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Is an ortholog of human PRKG1 (protein kinase cGMP-dependent 1). WB:WBGene00001174 egl-5 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including nematode male tail tip morphogenesis; neuron migration; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including neurons; non-striated muscle; ray precursor cell; rectal epithelial cell; and somatic nervous system. Is an ortholog of human HOXA7 (homeobox A7). WB:WBGene00001175 egl-6 Predicted to enable G protein-coupled peptide receptor activity. Involved in negative regulation of egg-laying behavior. Predicted to be located in plasma membrane. Expressed in GLR; nerve ring; and neurons. WB:WBGene00001176 egl-7 No description available WB:WBGene00001177 egl-8 Predicted to enable phosphatidylinositol phospholipase C activity. Involved in several processes, including dopamine receptor signaling pathway; positive regulation of acetylcholine secretion, neurotransmission; and taxis. Located in plasma membrane. Expressed in intestine; nervous system; non-striated muscle; and vas deferens. Used to study nicotine dependence. Is an ortholog of human PLCB4 (phospholipase C beta 4). WB:WBGene00001178 egl-9 Enables peptidyl-proline 4-dioxygenase activity. Involved in regulation of protein localization and response to hypoxia. Located in dendrite and nucleus. Expressed in ventral nerve cord and vulval precursor cell. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma and familial erythrocytosis 3. Is an ortholog of human EGLN1 (egl-9 family hypoxia inducible factor 1) and EGLN2 (egl-9 family hypoxia inducible factor 2). WB:WBGene00001179 egl-10 Predicted to enable GTPase activator activity. Involved in several processes, including dopamine receptor signaling pathway; regulation of egg-laying behavior; and rhythmic behavior. Located in cytoplasm and neuron projection. Expressed in body wall musculature and neurons. Is an ortholog of human RGS6 (regulator of G protein signaling 6) and RGS7 (regulator of G protein signaling 7). WB:WBGene00001180 egl-11 No description available WB:WBGene00001181 egl-12 No description available WB:WBGene00001182 egl-13 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell fate commitment; regulation of DNA-templated transcription; and vulval development. Located in nucleus. Expressed in several structures, including developing hermaphrodite gonad; egg-laying apparatus; intestinal cell; neurons; and uterine pi cell. Human ortholog(s) of this gene implicated in high grade glioma. Is an ortholog of human SOX13 (SRY-box transcription factor 13); SOX5 (SRY-box transcription factor 5); and SOX6 (SRY-box transcription factor 6). WB:WBGene00001183 egl-14 No description available WB:WBGene00001184 egl-15 Enables protein kinase activity. Involved in several processes, including egg-laying behavior; muscle cell cellular homeostasis; and regulation of protein stability. Predicted to be located in membrane. Predicted to be part of receptor complex. Expressed in head neurons; hypodermis; intestine; male sex myoblast; and vulval muscle. Used to study bone disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; bone disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human FGFR2 (fibroblast growth factor receptor 2). WB:WBGene00001185 egl-17 Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in regulation of cell migration and regulation of egg-laying behavior. Located in extracellular space. Expressed in several structures, including M4 neuron; P5.p; P7.p; male-specific anatomical entity; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including germ cell cancer (multiple); hypogonadotropic hypogonadism (multiple); and prostate disease (multiple). Is an ortholog of human FGF18 (fibroblast growth factor 18) and FGF8 (fibroblast growth factor 8). WB:WBGene00001186 egl-18 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cell fate specification; membrane fusion; and nematode larval development. Located in nucleus. Expressed in several structures, including ABprpppppaa; body wall muscle cell from MS lineage; nervous system; seam cell; and vulva. WB:WBGene00001187 egl-19 Enables voltage-gated calcium channel activity. Involved in several processes, including determination of left/right asymmetry in nervous system; positive regulation of striated muscle contraction; and regulation of pharyngeal pumping. Located in plasma membrane. Expressed in several structures, including alimentary muscle; body wall musculature; neurons; preanal ganglion; and tail. Used to study Duchenne muscular dystrophy and Timothy syndrome. Human ortholog(s) of this gene implicated in several diseases, including Brugada syndrome 3; X-linked recessive disease (multiple); and muscle tissue disease (multiple). Is an ortholog of human CACNA1C (calcium voltage-gated channel subunit alpha1 C); CACNA1F (calcium voltage-gated channel subunit alpha1 F); and CACNA1S (calcium voltage-gated channel subunit alpha1 S). WB:WBGene00001188 egl-20 Enables receptor tyrosine kinase binding activity. Involved in several processes, including left/right axis specification; neuron migration; and regulation of locomotion. Located in extracellular space. Expressed in several structures, including body wall muscle cell from C lineage; intestinal muscle; neuroblasts; rectal epithelial cell; and somatic nervous system. Is an ortholog of human WNT16 (Wnt family member 16). WB:WBGene00001189 egl-21 Enables carboxypeptidase activity. Involved in several processes, including cellular response to carbon dioxide; regulation of multicellular organismal process; and regulation of neurotransmitter levels. Located in axon; cytoplasmic vesicle; and neuronal cell body. Expressed in nervous system and uv1. Human ortholog(s) of this gene implicated in carboxypeptidase N deficiency; morbid obesity; and type 2 diabetes mellitus. Is an ortholog of human CPE (carboxypeptidase E). WB:WBGene00001190 egl-23 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00001191 egl-24 No description available WB:WBGene00001193 egl-26 Predicted to enable acyltransferase activity. Involved in several processes, including egg-laying behavior; positive regulation of vulval development; and vulval development. Located in cytoplasmic side of apical plasma membrane. Expressed in several structures, including buccal cavity; excretory canal; hermaphrodite gonad; rectum; and vulval cell. WB:WBGene00001194 egl-27 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; chromatin binding activity; and enzyme binding activity. Involved in several processes, including egg-laying behavior; hemidesmosome assembly; and nematode male tail tip morphogenesis. Located in nucleus. Expressed in several structures, including Y cell; intestinal cell; neurons; pharynx; and somatic gonad precursor. Human ortholog(s) of this gene implicated in dentatorubral-pallidoluysian atrophy and schizophrenia. Is an ortholog of human RERE (arginine-glutamic acid dipeptide repeats). WB:WBGene00001195 egl-28 No description available WB:WBGene00001196 egl-30 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in several processes, including cellular response to dopamine; regulation of localization; and regulation of locomotion. Located in axon; cell cortex; and neuronal cell body. Expressed in several structures, including vulval cell. Human ortholog(s) of this gene implicated in several diseases, including Sturge-Weber syndrome; autosomal dominant hypocalcemia 2; and familial hypocalciuric hypercalcemia 2. Is an ortholog of human GNA11 (G protein subunit alpha 11). WB:WBGene00001197 egl-31 No description available WB:WBGene00001198 egl-32 Acts upstream of or within egg-laying behavior; sensory perception of chemical stimulus; and transforming growth factor beta receptor signaling pathway. WB:WBGene00001199 egl-33 No description available WB:WBGene00001200 egl-34 No description available WB:WBGene00001201 egl-35 No description available WB:WBGene00001202 egl-36 Enables voltage-gated monoatomic ion channel activity. Involved in monoatomic ion transmembrane transport. Predicted to be located in somatodendritic compartment and synapse. Predicted to be part of voltage-gated potassium channel complex. Expressed in head muscle; hermaphrodite distal tip cell; neurons; non-striated muscle; and spermatheca. Human ortholog(s) of this gene implicated in Alzheimer's disease; electroclinical syndrome (multiple); and glioblastoma. Is an ortholog of human KCNC1 (potassium voltage-gated channel subfamily C member 1); KCNC2 (potassium voltage-gated channel subfamily C member 2); and KCNC4 (potassium voltage-gated channel subfamily C member 4). WB:WBGene00001203 egl-37 No description available WB:WBGene00001204 egl-38 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including developmental process involved in reproduction; positive regulation of transcription by RNA polymerase II; and vulval development. Located in nucleus. Expressed in body wall musculature; egg-laying apparatus; head neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including congenital nongoitrous hypothyroidism 2; focal segmental glomerulosclerosis 7; and renal Wilms' tumor. Is an ortholog of human PAX2 (paired box 2); PAX5 (paired box 5); and PAX8 (paired box 8). WB:WBGene00001205 egl-40 Acts upstream of or within dauer larval development. WB:WBGene00001206 egl-42 No description available WB:WBGene00001207 egl-43 Enables DNA-binding transcription factor activity. Involved in several processes, including regulation of developmental process; regulation of mitotic cell cycle; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including MSaaap; MSpaap; gonad; neurons; and somatic gonad precursor. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1LL and myeloid neoplasm. Is an ortholog of human MECOM (MDS1 and EVI1 complex locus) and PRDM16 (PR/SET domain 16). WB:WBGene00001208 egl-44 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and transcription coactivator binding activity. Involved in several processes, including generation of neurons; positive regulation of exit from mitosis; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including anterior hypodermis; body wall musculature; ganglia; neurons; and pharynx. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Is an ortholog of human TEAD2 (TEA domain transcription factor 2) and TEAD4 (TEA domain transcription factor 4). WB:WBGene00001209 egl-45 Predicted to enable mRNA binding activity and translation regulator activity. Predicted to contribute to translation initiation factor activity. Involved in egg-laying behavior and embryo development. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3e; eukaryotic translation initiation factor 3 complex, eIF3m; and multi-eIF complex. Expressed in neurons. Is an ortholog of human EIF3A (eukaryotic translation initiation factor 3 subunit A). WB:WBGene00001210 egl-46 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including detection of chemical stimulus; generation of neurons; and positive regulation of exit from mitosis. Located in nucleus. Expressed in several structures, including QL.aa; QL.pp; QR.aa; QR.pp; and neurons. Is an ortholog of human INSM2 (INSM transcriptional repressor 2). WB:WBGene00001211 egl-47 Predicted to enable G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and egg-laying behavior. Predicted to be located in axon; membrane; and somatodendritic compartment. Expressed in HSNL; HSNR; PVQL; PVQR; and vulva. WB:WBGene00001212 egl-49 No description available WB:WBGene00001213 egl-50 No description available WB:WBGene00001214 ego-1 Predicted to enable RNA-dependent RNA polymerase activity. Involved in gamete generation; nuclear pore localization; and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in P granule; condensed nuclear chromosome; and metaphase plate. Expressed in germ line. WB:WBGene00001215 ego-2 Involved in positive regulation of Notch signaling pathway and protein localization to basolateral plasma membrane. Located in cytoplasm and nucleus. Expressed widely. Is an ortholog of human PTPN23 (protein tyrosine phosphatase non-receptor type 23). WB:WBGene00001216 ego-3 No description available WB:WBGene00001217 ego-4 No description available WB:WBGene00001218 ego-5 No description available WB:WBGene00001220 eha-1 No description available WB:WBGene00001221 ehn-1 No description available WB:WBGene00001222 ehn-2 No description available WB:WBGene00001223 ehn-3 Predicted to enable metal ion binding activity. Involved in gonad development and positive regulation of gene expression. Located in nucleus. Expressed in Z1; Z4; and somatic gonad precursor. WB:WBGene00001224 ehs-1 Involved in chemical synaptic transmission and synaptic vesicle endocytosis. Located in axon; plasma membrane; and synapse. Expressed in epithelial cell; intestine; muscle cell; and nervous system. Is an ortholog of human EPS15 (epidermal growth factor receptor pathway substrate 15) and EPS15L1 (epidermal growth factor receptor pathway substrate 15 like 1). WB:WBGene00001225 eif-3.B Predicted to enable RNA binding activity and translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in regulation of translational initiation and translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Is an ortholog of human EIF3B (eukaryotic translation initiation factor 3 subunit B). WB:WBGene00001226 eif-3.C Predicted to enable translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Is an ortholog of human EIF3C (eukaryotic translation initiation factor 3 subunit C) and EIF3CL (eukaryotic translation initiation factor 3 subunit C like). WB:WBGene00001227 eif-3.D Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in pharynx. Is an ortholog of human EIF3D (eukaryotic translation initiation factor 3 subunit D). WB:WBGene00001228 eif-3.E Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in nucleus. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in head and tail. Is an ortholog of human EIF3E (eukaryotic translation initiation factor 3 subunit E). WB:WBGene00001229 eif-3.F Predicted to enable translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Involved in translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 67. Is an ortholog of human EIF3F (eukaryotic translation initiation factor 3 subunit F). WB:WBGene00001230 eif-3.G Enables mRNA 5'-UTR binding activity. Involved in positive regulation of translation. Located in cytoplasm. Expressed in germ line and somatic cell. Is an ortholog of human EIF3G (eukaryotic translation initiation factor 3 subunit G). WB:WBGene00001231 eif-3.H Predicted to enable metallopeptidase activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in formation of cytoplasmic translation initiation complex. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic 43S preinitiation complex; eukaryotic translation initiation factor 3 complex; and polysomal ribosome. Human ortholog(s) of this gene implicated in breast cancer and prostate carcinoma. Is an ortholog of human EIF3H (eukaryotic translation initiation factor 3 subunit H). WB:WBGene00001232 eif-3.I Predicted to enable RNA binding activity and translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Is an ortholog of human EIF3I (eukaryotic translation initiation factor 3 subunit I). WB:WBGene00001233 eif-3.K Predicted to enable RNA binding activity and ribosome binding activity. Predicted to contribute to translation initiation factor activity. Involved in positive regulation of apoptotic process. Located in cytoplasm. Expressed in several structures, including embryonic cell and germ line. Is an ortholog of human EIF3K (eukaryotic translation initiation factor 3 subunit K). WB:WBGene00001234 eif-6 Predicted to enable ribosomal large subunit binding activity. Involved in miRNA-mediated gene silencing. Predicted to be located in cytosol and nucleolus. Predicted to be part of preribosome, large subunit precursor. Used to study obesity. Is an ortholog of human EIF6 (eukaryotic translation initiation factor 6). WB:WBGene00001235 elb-1 Enables protein domain specific binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Part of Cul2-RING ubiquitin ligase complex. Is an ortholog of human ELOB (elongin B). WB:WBGene00001236 elc-1 Enables protein domain specific binding activity and protein-macromolecule adaptor activity. Involved in anterior/posterior axis specification, embryo; positive regulation of metaphase/anaphase transition of meiotic cell cycle; and sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation. Part of Cul2-RING ubiquitin ligase complex. Expressed in hypodermis; pharynx; and vulval muscle. Is an ortholog of human ELOC (elongin C). WB:WBGene00001237 elc-2 Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be part of elongin complex. Expressed in ADFL and ADFR. Is an ortholog of human ELOC (elongin C). WB:WBGene00001238 eld-1 No description available WB:WBGene00001239 elo-1 Predicted to enable fatty acid elongase activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in membrane. WB:WBGene00001240 elo-2 Predicted to enable fatty acid elongase activity. Involved in several processes, including determination of adult lifespan; lipid metabolic process; and regulation of gene expression. Predicted to be located in membrane. Expressed in intestine; pharyngeal muscle cell; tail; uterus; and ventral nerve cord. Is an ortholog of human ELOVL3 (ELOVL fatty acid elongase 3) and ELOVL6 (ELOVL fatty acid elongase 6). WB:WBGene00001241 elo-3 Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Expressed in tail. Is an ortholog of human ELOVL3 (ELOVL fatty acid elongase 3) and ELOVL6 (ELOVL fatty acid elongase 6). WB:WBGene00001242 elo-4 Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human ELOVL3 (ELOVL fatty acid elongase 3) and ELOVL6 (ELOVL fatty acid elongase 6). WB:WBGene00001243 elo-5 Predicted to enable fatty acid elongase activity. Involved in methyl-branched fatty acid biosynthetic process. Predicted to be located in membrane. Expressed in amphid neurons and intestine. WB:WBGene00001244 elo-6 Predicted to enable fatty acid elongase activity. Involved in methyl-branched fatty acid biosynthetic process. Predicted to be located in membrane. Expressed in amphid neurons; intestine; nerve ring; and vulva. WB:WBGene00001245 elo-7 Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to be located in membrane. WB:WBGene00001246 elo-8 Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to be located in membrane. WB:WBGene00001247 elo-9 Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to be located in membrane. Is an ortholog of human ELOVL3 (ELOVL fatty acid elongase 3) and ELOVL6 (ELOVL fatty acid elongase 6). WB:WBGene00001248 elp-1 Predicted to enable microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization. Located in dendrite; neuromuscular junction; and neuronal cell body. Expressed in several structures, including hypodermal cell; intestine; mechanosensory neurons; spermatheca; and vulval muscle. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in subcortical band heterotopia. Is an ortholog of human EML2 (EMAP like 2). WB:WBGene00001249 elt-1 Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including epidermal cell fate specification; regulation of transcription by RNA polymerase II; and spermatid development. Located in nucleus. Expressed in several structures, including V1L.a; V1R.a; V2L.a; seam cell; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including X-linked recessive disease (multiple); bone marrow cancer (multiple); and carcinoma (multiple). Is an ortholog of human GATA1 (GATA binding protein 1); GATA2 (GATA binding protein 2); and GATA3 (GATA binding protein 3). WB:WBGene00001250 elt-2 Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and enzyme inhibitor activity. Involved in several processes, including defense response to other organism; determination of adult lifespan; and nematode larval development. Located in nucleus. Expressed in several structures, including AWC; Ealaa; Ealp; Earaa; and intestine. Human ortholog(s) of this gene implicated in several diseases, including adenocarcinoma (multiple); artery disease (multiple); and congenital heart disease (multiple). Is an ortholog of human GATA4 (GATA binding protein 4); GATA5 (GATA binding protein 5); and GATA6 (GATA binding protein 6). WB:WBGene00001251 elt-3 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; lysosome organization; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including Caaaaa; Caaaap; hermaphrodite distal tip cell; hypodermal cell; and rectum. WB:WBGene00001252 elt-4 Enables double-stranded DNA binding activity. Involved in determination of adult lifespan and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in intestine; marginal cell; pm6; and pm7. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); congenital heart disease (multiple); and familial atrial fibrillation. Is an ortholog of human GATA5 (GATA binding protein 5). WB:WBGene00001253 elt-6 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate commitment; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABprpppppaa; and body wall muscle cell from MS lineage. WB:WBGene00001256 emb-2 No description available WB:WBGene00001257 emb-3 No description available WB:WBGene00001258 emb-4 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed in embryonic cell. Is an ortholog of human AQR (aquarius intron-binding spliceosomal factor). WB:WBGene00001259 emb-5 Predicted to enable histone binding activity and nucleosome binding activity. Predicted to be involved in nucleosome organization and transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Expressed in tail. Is an ortholog of human SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor). WB:WBGene00001261 emb-7 No description available WB:WBGene00001262 emb-8 Predicted to enable FMN binding activity; NADPH-hemoprotein reductase activity; and flavin adenine dinucleotide binding activity. Involved in eggshell formation and lipid biosynthetic process. Predicted to be located in cytosol. Expressed in intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in Antley-Bixler syndrome with disordered steroidogenesis; congenital adrenal hyperplasia; and cytochrome P450 oxidoreductase deficiency. Is an ortholog of human POR (cytochrome p450 oxidoreductase). WB:WBGene00001263 emb-9 Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in several processes, including positive regulation of axon regeneration; positive regulation of protein secretion; and response to serotonin. Located in basement membrane. Expressed in several structures, including coelomocyte; egg-laying apparatus; gonad; nerve ring; and rectal muscle. Human ortholog(s) of this gene implicated in several diseases, including X-linked Alport syndrome; X-linked deafness 6; and artery disease (multiple). Is an ortholog of human COL4A1 (collagen type IV alpha 1 chain). WB:WBGene00001265 emb-11 No description available WB:WBGene00001266 emb-12 No description available WB:WBGene00001267 emb-13 Acts upstream of or within embryonic morphogenesis. WB:WBGene00001269 emb-15 No description available WB:WBGene00001271 emb-17 No description available WB:WBGene00001272 emb-18 No description available WB:WBGene00001273 emb-19 No description available WB:WBGene00001274 emb-20 No description available WB:WBGene00001275 emb-21 No description available WB:WBGene00001276 emb-22 No description available WB:WBGene00001277 emb-23 No description available WB:WBGene00001278 emb-24 No description available WB:WBGene00001279 emb-25 No description available WB:WBGene00001280 emb-26 No description available WB:WBGene00001281 emb-27 Involved in asymmetric cell division; eggshell formation; and polarity specification of anterior/posterior axis. Located in synapse. Expressed in GABAergic neurons. Is an ortholog of human CDC16 (cell division cycle 16). WB:WBGene00001282 emb-28 No description available WB:WBGene00001284 emb-30 Involved in several processes, including anterior/posterior axis specification; asymmetric cell division; and metaphase/anaphase transition of meiosis I. Predicted to be located in nuclear periphery. Predicted to be part of anaphase-promoting complex. Is an ortholog of human ANAPC4 (anaphase promoting complex subunit 4). WB:WBGene00001285 emb-31 No description available WB:WBGene00001286 emb-32 No description available WB:WBGene00001287 emb-34 No description available WB:WBGene00001288 emb-35 No description available WB:WBGene00001289 emb-40 No description available WB:WBGene00001290 emb-46 No description available WB:WBGene00001291 emb-47 No description available WB:WBGene00001292 emb-48 No description available WB:WBGene00001293 emb-49 No description available WB:WBGene00001294 emb-50 No description available WB:WBGene00001295 emb-52 No description available WB:WBGene00001296 emb-53 No description available WB:WBGene00001297 emb-57 No description available WB:WBGene00001298 emb-60 No description available WB:WBGene00001299 emb-61 No description available WB:WBGene00001300 emb-62 No description available WB:WBGene00001301 emb-67 No description available WB:WBGene00001302 emb-85 No description available WB:WBGene00001303 sec-61.G Predicted to enable protein-transporting ATPase activity. Involved in oocyte growth and ovulation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of Sec61 translocon complex and Ssh1 translocon complex. Expressed in germ line. Is an ortholog of human SEC61G (SEC61 translocon subunit gamma). WB:WBGene00001304 emo-2 No description available WB:WBGene00001305 emo-3 No description available WB:WBGene00001306 emo-4 No description available WB:WBGene00001307 emo-5 No description available WB:WBGene00001308 emo-6 No description available WB:WBGene00001309 emr-1 Enables lamin binding activity. Involved in several processes, including mitotic cytokinesis; nuclear envelope organization; and response to X-ray. Located in nuclear inner membrane. Used to study Emery-Dreifuss muscular dystrophy. Is an ortholog of human LEMD1 (LEM domain containing 1). WB:WBGene00001310 end-1 Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in endodermal cell fate specification and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in E; E lineage cell; Ea; and Ep. WB:WBGene00001311 end-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate specification and mesodermal cell fate specification. Located in nucleus. Expressed in E; E lineage cell; Ea; Ep; and intestine. WB:WBGene00001312 eno-2 No description available WB:WBGene00001313 eno-3 No description available WB:WBGene00001314 eno-4 No description available WB:WBGene00001315 eno-6 No description available WB:WBGene00001316 eno-7 No description available WB:WBGene00001317 eno-8 No description available WB:WBGene00001318 eno-9 No description available WB:WBGene00001319 eno-11 No description available WB:WBGene00001320 ent-1 Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Located in plasma membrane. Expressed in intestine; isthmus; metacorpus; procorpus; and terminal bulb. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Is an ortholog of human SLC29A2 (solute carrier family 29 member 2) and SLC29A3 (solute carrier family 29 member 3). WB:WBGene00001322 enu-1 No description available WB:WBGene00001323 enu-2 No description available WB:WBGene00001324 eor-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; nematode male tail tip morphogenesis; and signal transduction. Located in nucleus. Expressed in several structures, including dorsal nerve cord; gonad; pharynx; and vulval precursor cell. WB:WBGene00001325 eor-2 Involved in several processes, including nematode male tail tip morphogenesis; neuron migration; and signal transduction. Located in nucleus. Expressed in several structures, including P5.ppp; hyp12; neurons; ventral nerve cord; and vulval cell. Is an ortholog of human CCDC82 (coiled-coil domain containing 82). WB:WBGene00001326 eos-1 Acts upstream of or within osmosensory signaling pathway. WB:WBGene00001327 eos-2 Acts upstream of or within osmosensory signaling pathway. WB:WBGene00001328 epi-1 Predicted to be an extracellular matrix structural constituent. Involved in several processes, including basement membrane organization; generation of neurons; and response to misfolded protein. Located in basement membrane. Expressed in several structures, including anal depressor muscle; basal lamina; body wall musculature; egg-laying apparatus; and intestine. Human ortholog(s) of this gene implicated in familial nephrotic syndrome; junctional epidermolysis bullosa; and lung small cell carcinoma. Is an ortholog of human LAMA5 (laminin subunit alpha 5). WB:WBGene00001329 epn-1 Predicted to enable clathrin binding activity and phospholipid binding activity. Predicted to be involved in endocytosis. Located in early phagosome; phagocytic cup; and pseudopodium. Expressed in anterior gonad arm; coelomocyte; head; intestine; and vulva. Is an ortholog of human EPN1 (epsin 1); EPN2 (epsin 2); and EPN3 (epsin 3). WB:WBGene00001330 eps-8 Enables actin filament binding activity. Involved in several processes, including anatomical structure morphogenesis; barbed-end actin filament capping; and supramolecular fiber organization. Located in apical part of cell; brush border; and hemidesmosome. Expressed in several structures, including P3.pa; P3.pp; P5.ppp; P7.paa; and P9.p. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 102; autosomal recessive nonsyndromic deafness 106; and hypotrichosis 5. Is an ortholog of human EPS8L1 (EPS8 like 1). WB:WBGene00001331 erd-2.1 Predicted to enable ER retention sequence binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in cis-Golgi network and endoplasmic reticulum. Expressed in head and tail. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 21. Is an ortholog of human KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2). WB:WBGene00001332 eri-1 Enables 3'-5'-RNA exonuclease activity. Involved in RNA metabolic process; regulation of gene expression; and sexual reproduction. Located in cytoplasm. Expressed in neurons and spermatheca. Is an ortholog of human ERI1 (exoribonuclease 1). WB:WBGene00001333 erm-1 Enables cytoskeletal anchor activity and structural molecule activity. Involved in several processes, including actin filament organization; nematode larval development; and protein localization to basolateral plasma membrane. Located in actin filament; apical part of cell; and membrane-enclosed lumen. Expressed in several structures, including PVD; excretory canal; germ line; germline precursor cell; and uterine toroidal epithelial cell. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 24 and immunodeficiency 50. Is an ortholog of human EZR (ezrin) and MSN (moesin). WB:WBGene00001334 ero-1 Predicted to enable protein-disulfide reductase activity. Involved in IRE1-mediated unfolded protein response and protein folding in endoplasmic reticulum. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human ERO1A (endoplasmic reticulum oxidoreductase 1 alpha) and ERO1B (endoplasmic reticulum oxidoreductase 1 beta). WB:WBGene00001335 F35A5.8 Predicted to be involved in membrane organization. Predicted to be located in membrane. Is an ortholog of human SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2). WB:WBGene00001336 qars-1 Predicted to enable glutamine-tRNA ligase activity. Predicted to be involved in glutaminyl-tRNA aminoacylation. Predicted to be located in cytosol. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Is an ortholog of human QARS1 (glutaminyl-tRNA synthetase 1). WB:WBGene00001337 ears-1 Predicted to enable glutamate-tRNA ligase activity. Predicted to be involved in glutamyl-tRNA aminoacylation. Predicted to be located in cytosol. Predicted to be part of methionyl glutamyl tRNA synthetase complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 15. Is an ortholog of human EPRS1 (glutamyl-prolyl-tRNA synthetase 1). WB:WBGene00001338 ears-2 Predicted to enable glutamate-tRNA ligase activity. Predicted to be involved in glutamyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 12. Is an ortholog of human EARS2 (glutamyl-tRNA synthetase 2, mitochondrial). WB:WBGene00001340 etr-1 Predicted to enable mRNA 3'-UTR binding activity. Involved in determination of adult lifespan. Located in nucleus. Expressed in body wall musculature; cloacal sphincter muscle; copulatory spicule; non-striated muscle; and somatic gonad. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 97. Is an ortholog of human CELF1 (CUGBP Elav-like family member 1). WB:WBGene00001341 evl-1 No description available WB:WBGene00001342 evl-2 No description available WB:WBGene00001343 evl-3 No description available WB:WBGene00001344 evl-4 No description available WB:WBGene00001345 fos-1 Enables several functions, including RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; chromatin binding activity; and identical protein binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of stress response to copper ion; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including gonad; neurons; uterine pi cell; ventral uterine precursor; and vulval cell. WB:WBGene00001346 evl-6 No description available WB:WBGene00001347 evl-7 No description available WB:WBGene00001348 evl-8 No description available WB:WBGene00001349 evl-9 No description available WB:WBGene00001350 evl-12 No description available WB:WBGene00001351 evl-13 No description available WB:WBGene00001352 evl-14 Involved in meiotic sister chromatid cohesion and mitotic sister chromatid cohesion. Predicted to be located in nucleus. Predicted to be part of chromatin. Is an ortholog of human PDS5A (PDS5 cohesin associated factor A) and PDS5B (PDS5 cohesin associated factor B). WB:WBGene00001353 evl-15 No description available WB:WBGene00001354 evl-16 No description available WB:WBGene00001355 evl-17 No description available WB:WBGene00001357 evl-19 No description available WB:WBGene00001358 evl-20 Predicted to enable GTP binding activity. Involved in several processes, including cortical microtubule organization; female genitalia development; and mitotic cytokinesis. Located in cytoplasm; microtubule cytoskeleton; and plasma membrane. Expressed in several structures, including P3.p hermaphrodite; hermaphrodite gonad; hyp12; proctodeum; and vulval cell. Is an ortholog of human ARL2 (ADP ribosylation factor like GTPase 2). WB:WBGene00001359 evl-21 No description available WB:WBGene00001360 evl-23 No description available WB:WBGene00001361 evl-24 No description available WB:WBGene00001362 exc-1 Predicted to enable GTP binding activity. Involved in epithelial cell development and regulation of tube size. Predicted to be located in membrane. Expressed in amphid sheath cell and excretory canal. WB:WBGene00001364 exc-3 Acts upstream of or within epithelial cell development and regulation of tube size. WB:WBGene00001365 exc-4 Predicted to enable chloride channel activity. Involved in epithelial cell development and regulation of tube size. Located in apical junction complex; apical plasma membrane; and lysosome. Expressed in several structures, including amphid sheath cell; excretory system; pharyngeal muscle cell; rectum; and vulva. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in X-linked intellectual disability-cardiomegaly-congestive heart failure syndrome and autosomal recessive nonsyndromic deafness 103. Is an ortholog of human CLIC2 (chloride intracellular channel 2) and CLIC4 (chloride intracellular channel 4). WB:WBGene00001366 exc-5 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in cell morphogenesis; epithelial cell development; and regulation of tube size. Located in several cellular components, including actin cytoskeleton; apical cortex; and cell body. Expressed in excretory cell; hermaphrodite gonad; neurons; pharyngeal muscle cell; and rectal epithelium. Used to study Charcot-Marie-Tooth disease type 4H and X-linked Aarskog syndrome. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 4H; X-linked Aarskog syndrome; and invasive ductal carcinoma. Is an ortholog of several human genes including FGD1 (FYVE, RhoGEF and PH domain containing 1); FGD3 (FYVE, RhoGEF and PH domain containing 3); and FGD4 (FYVE, RhoGEF and PH domain containing 4). WB:WBGene00001368 exc-7 Enables single-stranded RNA binding activity. Involved in several processes, including epithelial cell development; regulation of alternative mRNA splicing, via spliceosome; and regulation of neuron differentiation. Located in nuclear speck. Expressed in several structures, including excretory cell; neurons; somatic nervous system; tail; and vulva. Is an ortholog of human ELAVL4 (ELAV like RNA binding protein 4). WB:WBGene00001369 exc-8 Acts upstream of or within epithelial cell development and regulation of tube size. WB:WBGene00001371 exl-1 Predicted to enable chloride channel activity. Predicted to be involved in chloride transport. Located in apical plasma membrane; cytoplasm; and muscle cell projection membrane. Expressed in coelomocyte; intestine; muscle cell; and neurons. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in X-linked intellectual disability-cardiomegaly-congestive heart failure syndrome. Is an ortholog of human CLIC2 (chloride intracellular channel 2) and CLIC4 (chloride intracellular channel 4). WB:WBGene00001372 exo-3 Enables DNA-(apurinic or apyrimidinic site) endonuclease activity and phosphoric diester hydrolase activity. Involved in base-excision repair; embryo development; and nematode larval development. Predicted to be located in nucleus. Expressed in hermaphrodite gonad and male gonad. Human ortholog(s) of this gene implicated in several diseases, including female reproductive organ cancer (multiple); prostate carcinoma in situ; and spina bifida. Is an ortholog of human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1). WB:WBGene00001373 exp-1 Enables GABA receptor activity and excitatory extracellular ligand-gated monoatomic ion channel activity. Involved in several processes, including lipid transport involved in lipid storage; metal ion transport; and positive regulation of multicellular organismal process. Located in neuromuscular junction. Expressed in Y cell; enteric muscle; and neurons. WB:WBGene00001374 exp-2 Enables inward rectifier potassium channel activity. Involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Expressed in intestinal cell; muscle cell; nerve ring; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26. Is an ortholog of human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1). WB:WBGene00001375 exp-3 No description available WB:WBGene00001376 exp-4 No description available WB:WBGene00001377 eya-1 Predicted to enable protein tyrosine phosphatase activity and transcription coactivator activity. Involved in several processes, including egg-laying behavior; positive regulation of cellular response to heat; and regulation of apoptotic process. Located in nucleus. Expressed in several structures, including body wall musculature; intestine; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including auditory system disease (multiple); branchiootorenal syndrome 1; and dilated cardiomyopathy 1J. Is an ortholog of several human genes including EYA1 (EYA transcriptional coactivator and phosphatase 1); EYA2 (EYA transcriptional coactivator and phosphatase 2); and EYA4 (EYA transcriptional coactivator and phosphatase 4). WB:WBGene00001378 fab-1 No description available WB:WBGene00001379 fab-2 No description available WB:WBGene00001380 fab-3 No description available WB:WBGene00001381 fab-4 No description available WB:WBGene00001382 faf-1 No description available WB:WBGene00001383 fam-1 No description available WB:WBGene00001384 fam-2 No description available WB:WBGene00001385 far-1 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Expressed in male. WB:WBGene00001386 far-2 Predicted to enable fatty acid binding activity and retinol binding activity. Predicted to be located in extracellular region. Expressed in body wall musculature; vulval muscle; and in male. WB:WBGene00001387 far-3 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Expressed in vulva and in male. WB:WBGene00001388 far-4 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. WB:WBGene00001389 far-5 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Expressed in male. WB:WBGene00001390 far-6 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Expressed in male. WB:WBGene00001391 far-7 Enables oleic acid binding activity. Located in cytoplasm. Expressed in excretory canal; excretory cell; hypodermis; and in male. WB:WBGene00001392 far-8 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. WB:WBGene00001393 fat-1 Predicted to enable oxidoreductase activity. Involved in positive regulation of locomotion and unsaturated fatty acid biosynthetic process. Predicted to be located in membrane. Expressed in intestine; nerve ring; and touch receptor neurons. Used to study alcohol use disorder. WB:WBGene00001394 fat-2 Enables stearoyl-CoA 9-desaturase activity. Involved in several processes, including collagen and cuticulin-based cuticle development; fatty acid biosynthetic process; and innate immune response. Predicted to be located in membrane. WB:WBGene00001395 fat-3 Enables stearoyl-CoA 9-desaturase activity. Involved in several processes, including egg-laying behavior; signal release; and system process. Predicted to be located in membrane. Expressed in body wall musculature; head neurons; intestine; pharynx; and tail neurons. Used to study alcohol use disorder and lipid metabolism disorder. Is an ortholog of human FADS2 (fatty acid desaturase 2) and FADS3 (fatty acid desaturase 3). WB:WBGene00001396 fat-4 Enables stearoyl-CoA 9-desaturase activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in membrane. Expressed in nerve ring and touch receptor neurons. Used to study alcohol use disorder. Is an ortholog of human FADS1 (fatty acid desaturase 1). WB:WBGene00001397 fat-5 Predicted to enable iron ion binding activity and stearoyl-CoA 9-desaturase activity. Involved in long-chain fatty acid biosynthetic process and post-embryonic development. Predicted to be located in endoplasmic reticulum membrane. Expressed in intestine and tail. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Is an ortholog of human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5). WB:WBGene00001398 fat-6 Enables stearoyl-CoA 9-desaturase activity. Involved in innate immune response; long-chain fatty acid biosynthetic process; and post-embryonic development. Predicted to be located in endoplasmic reticulum membrane. Expressed in hypodermis. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Is an ortholog of human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5). WB:WBGene00001399 fat-7 Enables stearoyl-CoA 9-desaturase activity. Involved in fatty acid biosynthetic process and post-embryonic development. Acts upstream of or within intracellular oxygen homeostasis and response to hypoxia. Predicted to be located in endoplasmic reticulum membrane. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Is an ortholog of human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5). WB:WBGene00001400 fax-1 Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including neuron differentiation; positive regulation of transcription by RNA polymerase II; and regulation of locomotion. Located in nucleus. Expressed in several structures, including CEP; hermaphrodite distal tip cell; interneuron; pharyngeal motor neurons; and rect_D. Human ortholog(s) of this gene implicated in enhanced S-cone syndrome and retinitis pigmentosa 37. Is an ortholog of human NR2E3 (nuclear receptor subfamily 2 group E member 3). WB:WBGene00001401 fbf-1 Enables mRNA 3'-UTR binding activity. Involved in several processes, including germline cell cycle switching, mitotic to meiotic cell cycle; olfactory learning; and regulation of gene expression. Located in germ cell nucleus and perinuclear region of cytoplasm. Expressed in germ line. WB:WBGene00001402 fbf-2 Enables mRNA 3'-UTR binding activity. Involved in negative regulation of translation. Located in P granule. Used to study obesity. WB:WBGene00001403 fbl-1 An extracellular matrix structural constituent. Involved in extracellular matrix organization; positive regulation of locomotion; and protein localization. Located in basement membrane. Expressed in ALM; GLR; basal lamina; hyp7 syncytium; and nerve ring. Is an ortholog of human FBLN1 (fibulin 1). WB:WBGene00001404 fbp-1 Predicted to enable fructose 1,6-bisphosphate 1-phosphatase activity. Predicted to be involved in carbohydrate metabolic process and organophosphate metabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in fructose-1,6-bisphosphatase deficiency. Is an ortholog of human FBP1 (fructose-bisphosphatase 1) and FBP2 (fructose-bisphosphatase 2). WB:WBGene00001405 fce-1 Enables metalloendopeptidase activity. Involved in CAAX-box protein processing. Located in membrane. Expressed in head. Human ortholog(s) of this gene implicated in mandibuloacral dysplasia type B lipodystrophy and restrictive dermopathy 1. Is an ortholog of human ZMPSTE24 (zinc metallopeptidase STE24). WB:WBGene00001406 fce-2 Enables cysteine-type endopeptidase activity. Involved in CAAX-box protein processing. Located in membrane. Is an ortholog of human RCE1 (Ras converting CAAX endopeptidase 1). WB:WBGene00001407 feb-1 No description available WB:WBGene00001408 fed-1 No description available WB:WBGene00001409 fed-2 No description available WB:WBGene00001410 feh-1 Enables amyloid-beta binding activity. Involved in embryo development; feeding behavior; and nematode larval development. Located in actin filament. Expressed in nerve ring; pharynx; tail neurons; and ventral cord neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease and cognitive disorder. Is an ortholog of human APBB2 (amyloid beta precursor protein binding family B member 2). WB:WBGene00001411 fem-1 Enables protein phosphatase binding activity. Involved in several processes, including proteasome-mediated ubiquitin-dependent protein catabolic process; regulation of germ cell proliferation; and sex determination. Located in protein-containing complex. Part of Cul2-RING ubiquitin ligase complex. Expressed in several structures, including germ line. Is an ortholog of human FEM1A (fem-1 homolog A) and FEM1C (fem-1 homolog C). WB:WBGene00001412 fem-2 Enables calmodulin-dependent protein phosphatase activity. Involved in male sex determination; masculinization of hermaphroditic germ-line; and nematode male tail tip morphogenesis. Located in protein-containing complex. Is an ortholog of human PPM1F (protein phosphatase, Mg2+/Mn2+ dependent 1F). WB:WBGene00001413 fem-3 Enables protein phosphatase binding activity. Involved in several processes, including protein localization to chromatin; regulation of reproductive process; and sex determination. Located in cytoplasm and protein-containing complex. Expressed in germ line; spermatid; and in male. WB:WBGene00001414 fer-1 Predicted to enable calcium-dependent phospholipid binding activity. Involved in several processes, including amoeboid sperm motility; membrane organization; and pseudopodium organization. Located in neuronal cell body membrane; organelle membrane; and pseudopodium membrane. Expressed in body wall muscle cell; spermatid; spermatocyte; and in male. Used to study limb-girdle muscular dystrophy. Human ortholog(s) of this gene implicated in Miyoshi muscular dystrophy 1; autosomal recessive limb-girdle muscular dystrophy type 2B; autosomal recessive nonsyndromic deafness 9; distal muscular dystrophy with anterior tibial onset; and hereditary angioedema. Is an ortholog of human DYSF (dysferlin) and MYOF (myoferlin). WB:WBGene00001415 fer-2 No description available WB:WBGene00001417 fer-4 No description available WB:WBGene00001418 fer-6 No description available WB:WBGene00001419 fer-7 No description available WB:WBGene00001420 fer-14 No description available WB:WBGene00001423 fib-1 Predicted to enable RNA binding activity; histone H2AQ104 methyltransferase activity; and rRNA methyltransferase activity. Involved in nucleologenesis and positive regulation of translation. Located in nucleolus and nucleoplasm. Is an ortholog of human FBL (fibrillarin). WB:WBGene00001424 fis-1 Predicted to be involved in mitochondrion organization and peroxisome fission. Located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human FIS1 (fission, mitochondrial 1). WB:WBGene00001425 fis-2 Involved in apoptotic process. Acts upstream of or within IRE1-mediated unfolded protein response. Located in mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human FIS1 (fission, mitochondrial 1). WB:WBGene00001426 fkb-1 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in chaperone-mediated protein folding. Is an ortholog of human FKBP2 (FKBP prolyl isomerase 2). WB:WBGene00001427 fkb-2 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Graves' disease. Is an ortholog of human FKBP1A (FKBP prolyl isomerase 1A); FKBP1B (FKBP prolyl isomerase 1B); and FKBP1C (FKBP prolyl isomerase family member 1C). WB:WBGene00001428 fkb-3 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum. Expressed in hypodermis. Is an ortholog of human FKBP9 (FKBP prolyl isomerase 9). WB:WBGene00001429 fkb-4 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 11. Is an ortholog of human FKBP10 (FKBP prolyl isomerase 10) and FKBP9 (FKBP prolyl isomerase 9). WB:WBGene00001430 fkb-5 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum. Expressed in hypodermis. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 11. Is an ortholog of human FKBP10 (FKBP prolyl isomerase 10) and FKBP9 (FKBP prolyl isomerase 9). WB:WBGene00001431 fkb-6 Enables Hsp90 protein binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in chaperone-mediated protein folding. Predicted to be located in cytoplasm. Expressed in dorsal nerve cord; intestine; and ventral nerve cord. Human ortholog(s) of this gene implicated in major depressive disorder. Is an ortholog of human FKBP4 (FKBP prolyl isomerase 4) and FKBP5 (FKBP prolyl isomerase 5). WB:WBGene00001432 fkb-7 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome kyphoscoliotic type 2. Is an ortholog of human FKBP14 (FKBP prolyl isomerase 14) and FKBP7 (FKBP prolyl isomerase 7). WB:WBGene00001433 fkb-8 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be located in cytoplasm. WB:WBGene00001434 fkh-2 Enables DNA-binding transcription factor activity. Involved in several processes, including nematode larval development; neuron differentiation; and non-motile cilium assembly. Located in nucleus. Expressed in several structures, including AWB; Daaa; body wall muscle cell from D lineage; head muscle; and somatic nervous system. Is an ortholog of human FOXG1 (forkhead box G1). WB:WBGene00001435 fkh-3 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00001436 fkh-4 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Located in nucleus. WB:WBGene00001437 fkh-5 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons. WB:WBGene00001438 fkh-6 Enables sequence-specific DNA binding activity. Involved in male germ-line sex determination and male gonad development. Predicted to be located in nucleus. Expressed in gonadal sheath cell; male gonad; somatic gonad precursor; spermatheca; and in male. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 4. Is an ortholog of human FOXI2 (forkhead box I2) and FOXI3 (forkhead box I3). WB:WBGene00001439 fkh-7 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including intestine; neurons; pharynx; reproductive system; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); communication disorder (multiple); and tuberculosis (multiple). Is an ortholog of human FOXP2 (forkhead box P2). WB:WBGene00001440 fkh-8 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ASEL; ASER; head neurons; neurons; and tail neurons. Human ortholog(s) of this gene implicated in several diseases, including lymphedema-distichiasis syndrome; obesity; and type 2 diabetes mellitus. Is an ortholog of human FOXC2 (forkhead box C2); FOXL3 (forkhead box L3); and FOXL3-OT1. WB:WBGene00001441 fkh-9 Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including axon regeneration; determination of adult lifespan; and learning or memory. Acts upstream of or within ERAD pathway and defense response to other organism. Located in nucleus. Expressed in several structures, including intestine; neurons; pharyngeal-intestinal valve; rectal valve cell; and somatic nervous system. WB:WBGene00001442 fkh-10 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in gonad and pharyngeal neurons. Is an ortholog of human FOXL3 (forkhead box L3) and FOXL3-OT1. WB:WBGene00001443 fli-1 Predicted to enable actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in actin filament-based process and barbed-end actin filament capping. Located in nucleus. Expressed in body wall musculature; germ line; hermaphrodite gonad; and non-striated muscle. Is an ortholog of human FLII (FLII actin remodeling protein). WB:WBGene00001444 flp-1 Enables neuropeptide receptor binding activity. Involved in several processes, including mechanosensory behavior; regulation of egg-laying behavior; and response to serotonin. Predicted to be located in extracellular region. Expressed in RIG; nerve ring; and neurons. WB:WBGene00001445 flp-2 Involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of protein secretion; and sleep. Acts upstream of with a positive effect on mitochondrial unfolded protein response. Expressed in MC neuron; interneuron; and nerve ring. WB:WBGene00001446 flp-3 Involved in negative regulation of action potential; neuropeptide signaling pathway; and regulation of pharyngeal pumping. Predicted to be located in extracellular region. Expressed in head; motor neurons; sensory neurons; somatic nervous system; and in male. WB:WBGene00001447 flp-4 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in nerve ring; pharyngeal neurons; and sensory neurons. WB:WBGene00001448 flp-5 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in head; neurons; and pharyngeal muscle cell. WB:WBGene00001449 flp-6 Predicted to enable receptor ligand activity. Involved in several processes, including determination of adult lifespan; germ-line stem cell population maintenance; and response to heat. Predicted to be located in extracellular region. Expressed in several structures, including anal region; ciliated neurons; head mesodermal cell; interneuron; and nerve ring. WB:WBGene00001450 flp-7 Enables neuropeptide receptor binding activity. Involved in negative regulation of locomotion; neuropeptide signaling pathway; and second-messenger-mediated signaling. Located in extracellular space. Expressed in nerve ring and neurons. WB:WBGene00001451 flp-8 Involved in negative regulation of turning behavior involved in mating. Predicted to be located in extracellular region. Expressed in PVM; head; nerve ring; and tail. WB:WBGene00001452 flp-9 Enables neuropeptide receptor binding activity. Involved in action potential; locomotory behavior; and neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in nerve ring. WB:WBGene00001453 flp-10 Involved in negative regulation of egg-laying behavior; negative regulation of turning behavior involved in mating; and thigmotaxis. Expressed in nerve ring and neurons. WB:WBGene00001454 flp-11 Enables neuropeptide receptor binding activity. Involved in neuropeptide signaling pathway and sleep. Predicted to be located in extracellular region. Expressed in nerve ring; neurons; and uv1. WB:WBGene00001455 flp-12 Involved in negative regulation of turning behavior involved in mating. Expressed in nerve ring and neurons. WB:WBGene00001456 flp-13 Enables neuropeptide receptor binding activity. Involved in neuropeptide signaling pathway; regulation of cellular response to heat; and regulation of circadian sleep/wake cycle, sleep. Predicted to be located in extracellular region. Expressed in nerve ring; neurons; and spicule protractor muscle. WB:WBGene00001457 flp-14 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in axon; extracellular region; and perikaryon. Expressed in ganglia and nerve ring. WB:WBGene00001458 flp-15 Expressed in I2 neuron; PHA; accessory cell; and nerve ring. WB:WBGene00001459 flp-16 Involved in cellular response to carbon dioxide; negative regulation of pharyngeal pumping; and negative regulation of striated muscle contraction. Predicted to be located in extracellular region. Expressed in nerve ring. WB:WBGene00001460 flp-17 Involved in negative regulation of egg-laying behavior. Located in neuron projection and neuronal cell body. Expressed in BAG; nerve ring; and neurons. WB:WBGene00001461 flp-18 Predicted to enable neuropeptide Y receptor binding activity. Involved in neuropeptide signaling pathway; regulation of muscle contraction; and sleep. Predicted to be located in extracellular space. Expressed in coelomocyte; head; neurons; tail; and in male. WB:WBGene00001462 flp-19 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in HSN; head neurons; nerve ring; and tail. WB:WBGene00001463 flp-20 Involved in negative regulation of turning behavior involved in mating. Expressed in head mesodermal cell; nerve ring; and neurons. WB:WBGene00001464 flp-21 Enables neuropeptide Y receptor binding activity. Involved in G protein-coupled receptor signaling pathway; feeding behavior; and sleep. Predicted to be located in extracellular space. Expressed in several structures, including P9; head neurons; pharyngeal neurons; spicule neurons; and tail neurons. WB:WBGene00001465 flr-1 Predicted to enable ligand-gated sodium channel activity. Involved in defecation and ultradian rhythm. Located in nuclear membrane and plasma membrane. Is an ortholog of human ASIC1 (acid sensing ion channel subunit 1); ASIC2 (acid sensing ion channel subunit 2); and ASIC3 (acid sensing ion channel subunit 3). WB:WBGene00001466 gpla-1 Predicted to enable hormone receptor binding activity. Predicted to be involved in cell surface receptor signaling pathway. Located in extracellular space. Expressed in interneuron and pharyngeal neurons. Is an ortholog of human GPHA2 (glycoprotein hormone subunit alpha 2). WB:WBGene00001467 flr-3 No description available WB:WBGene00001468 flr-4 Predicted to enable protein serine/threonine kinase activity. Involved in defecation. Located in plasma membrane. Expressed in AUAL; AUAR; intestine; isthmus; and neurons. WB:WBGene00001469 flr-5 No description available WB:WBGene00001470 baz-2 Predicted to enable DNA binding activity and metal ion binding activity. Part of chromatin. Expressed in several structures, including AB lineage cell; ABplappppa; hermaphrodite distal tip cell; neurons; and vulva. Is an ortholog of human BAZ2A (bromodomain adjacent to zinc finger domain 2A) and BAZ2B (bromodomain adjacent to zinc finger domain 2B). WB:WBGene00001471 flu-1 No description available WB:WBGene00001473 flu-3 No description available WB:WBGene00001474 flu-4 No description available WB:WBGene00001475 fmi-1 Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Involved in anterior/posterior axon guidance and interneuron axon guidance. Located in axon. Expressed in nervous system and somatic nervous system. Human ortholog(s) of this gene implicated in hereditary lymphedema. Is an ortholog of human CELSR2 (cadherin EGF LAG seven-pass G-type receptor 2). WB:WBGene00001476 fmo-1 Predicted to enable monooxygenase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Expressed in excretory gland cell and head. Human ortholog(s) of this gene implicated in hypertension and trimethylaminuria. Is an ortholog of several human genes including FMO2 (flavin containing dimethylaniline monoxygenase 2); FMO3 (flavin containing dimethylaniline monoxygenase 3); and FMO4 (flavin containing dimethylaniline monoxygenase 4). WB:WBGene00001477 fmo-2 Enables monooxygenase activity. Involved in defense response to Gram-negative bacterium and one-carbon metabolic process. Located in cytoplasm. Expressed in excretory gland cell; head; intestinal cell; intestine; and neurons. Human ortholog(s) of this gene implicated in hypertension and trimethylaminuria. Is an ortholog of several human genes including FMO2 (flavin containing dimethylaniline monoxygenase 2); FMO3 (flavin containing dimethylaniline monoxygenase 3); and FMO4 (flavin containing dimethylaniline monoxygenase 4). WB:WBGene00001478 fmo-3 Predicted to enable monooxygenase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hypertension and trimethylaminuria. Is an ortholog of several human genes including FMO2 (flavin containing dimethylaniline monoxygenase 2); FMO3 (flavin containing dimethylaniline monoxygenase 3); and FMO4 (flavin containing dimethylaniline monoxygenase 4). WB:WBGene00001479 fmo-4 Predicted to enable monooxygenase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Expressed in excretory duct cell; excretory socket cell; hypodermal cell; intestine; and ventral nerve cord. Human ortholog(s) of this gene implicated in hypertension and trimethylaminuria. Is an ortholog of several human genes including FMO2 (flavin containing dimethylaniline monoxygenase 2); FMO3 (flavin containing dimethylaniline monoxygenase 3); and FMO4 (flavin containing dimethylaniline monoxygenase 4). WB:WBGene00001480 fmo-5 Predicted to enable monooxygenase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Expressed in excretory gland cell; intestine; and ventral nerve cord. Human ortholog(s) of this gene implicated in hypertension and trimethylaminuria. Is an ortholog of several human genes including FMO2 (flavin containing dimethylaniline monoxygenase 2); FMO3 (flavin containing dimethylaniline monoxygenase 3); and FMO4 (flavin containing dimethylaniline monoxygenase 4). WB:WBGene00001481 fog-1 Enables mRNA 3'-UTR binding activity. Involved in cell fate specification; germ-line sex determination; and spermatogenesis. Located in cytoplasm and nuclear periphery. Expressed in germ line. WB:WBGene00001482 fog-2 Involved in several processes, including cytoplasmic streaming; developmental process involved in reproduction; and positive regulation of cell differentiation. Located in cytoplasm. Expressed in germ line. WB:WBGene00001483 fog-3 Predicted to enable transcription corepressor activity. Involved in cell fate specification; developmental process involved in reproduction; and positive regulation of oocyte development. Located in cytoplasm and nuclear periphery. Expressed in germ line. Is an ortholog of human TOB1 (transducer of ERBB2, 1). WB:WBGene00001484 fox-1 Enables pre-mRNA intronic binding activity and single-stranded RNA binding activity. Involved in several processes, including intergenic mRNA trans splicing; primary sex determination; and regulation of gene expression. Located in nucleus. Expressed in body wall musculature; intestine; pharynx; and vulval muscle. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; hypoplastic left heart syndrome; myotonic dystrophy type 1; and type 2 diabetes mellitus. Is an ortholog of human RBFOX1 (RNA binding fox-1 homolog 1) and RBFOX3 (RNA binding fox-1 homolog 3). WB:WBGene00001485 fre-1 Predicted to enable FMN binding activity; flavin adenine dinucleotide binding activity; and oxidoreductase activity. Predicted to be involved in iron-sulfur cluster assembly. Located in nucleus. Expressed in neurons and pharyngeal muscle cell. Is an ortholog of human NDOR1 (NADPH dependent diflavin oxidoreductase 1). WB:WBGene00001486 frh-1 Predicted to enable several functions, including 2 iron, 2 sulfur cluster binding activity; ferroxidase activity; and iron ion binding activity. Involved in determination of adult lifespan; response to hydrogen peroxide; and response to superoxide. Located in mitochondrion. Expressed in amphid neurons; body wall musculature; pharyngeal muscle cell; and spermatheca. Used to study Friedreich ataxia. Human ortholog(s) of this gene implicated in Friedreich ataxia 1 and type 2 diabetes mellitus. Is an ortholog of human FXN (frataxin). WB:WBGene00001487 frk-1 Enables beta-catenin binding activity and protein kinase activity. Involved in several processes, including embryonic body morphogenesis; negative regulation of canonical Wnt signaling pathway; and regulation of epidermal cell differentiation. Located in several cellular components, including cell-cell junction; nucleus; and plasma membrane. Expressed in several structures, including germ line; hermaphrodite gonad; hypodermis; intestine; and sperm. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00001488 frm-1 Predicted to enable actin binding activity and structural molecule activity. Predicted to be involved in actomyosin structure organization. Located in plasma membrane. Expressed in several structures, including intestine and pharynx. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 11; esophagus squamous cell carcinoma; and meningioma. Is an ortholog of human EPB41L1 (erythrocyte membrane protein band 4.1 like 1) and EPB41L3 (erythrocyte membrane protein band 4.1 like 3). WB:WBGene00001489 frm-2 Predicted to enable cytoskeletal protein binding activity. Predicted to be involved in actomyosin structure organization. Predicted to be located in cytoskeleton. Expressed in intestinal cell; pharyngeal epithelial cell; and sensory neurons. Is an ortholog of human EPB41L4B (erythrocyte membrane protein band 4.1 like 4B) and EPB41L5 (erythrocyte membrane protein band 4.1 like 5). WB:WBGene00001490 frm-3 Enables GABA receptor binding activity. Involved in gamma-aminobutyric acid receptor clustering. Predicted to be located in adherens junction and plasma membrane. Expressed in dorsal nerve cord. Human ortholog(s) of this gene implicated in congenital nystagmus 1. Is an ortholog of human FARP2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2). WB:WBGene00001491 frm-4 Predicted to be involved in actomyosin structure organization. Predicted to be located in cytoskeleton. Expressed in PVDL; PVDR; head; and tail. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with eye movement abnormalities and ataxia. Is an ortholog of human FRMD3 (FERM domain containing 3) and FRMD5 (FERM domain containing 5). WB:WBGene00001492 frm-5.1 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Is an ortholog of human FRMPD2 (FERM and PDZ domain containing 2). WB:WBGene00001493 frm-7 Predicted to be involved in positive regulation of hippo signaling. Predicted to be located in cytoplasmic side of apical plasma membrane. Is an ortholog of human FRMD1 (FERM domain containing 1). WB:WBGene00001494 frm-8 Expressed in PVDL and PVDR. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 104. Human FRMPD4 enables phosphatidylinositol-4,5-bisphosphate binding activity. Is predicted to encode a protein with the following domains: FERM/acyl-CoA-binding protein superfamily; Ubiquitin-like domain superfamily; FERM superfamily, second domain; WW domain; PDZ superfamily; Band 4.1 domain; PDZ domain; and FERM central domain. Is an ortholog of human FRMPD1 (FERM and PDZ domain containing 1); FRMPD3 (FERM and PDZ domain containing 3); and FRMPD4 (FERM and PDZ domain containing 4). WB:WBGene00001495 F31B12.3 Enriched in head mesodermal cell; neurons; and spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00001496 frm-10 Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to be located in plasma membrane. Is an ortholog of human FRMD8 (FERM domain containing 8). WB:WBGene00001497 fars-1 Predicted to enable phenylalanine-tRNA ligase activity. Involved in translation. Predicted to be located in cytoplasm. Predicted to be part of phenylalanine-tRNA ligase complex. Is an ortholog of human FARSA (phenylalanyl-tRNA synthetase subunit alpha). WB:WBGene00001498 fars-3 Predicted to enable magnesium ion binding activity. Predicted to contribute to phenylalanine-tRNA ligase activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Predicted to be part of phenylalanine-tRNA ligase complex. Is an ortholog of human FARSB (phenylalanyl-tRNA synthetase subunit beta). WB:WBGene00001499 fsn-1 Enables protease binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of neuron projection development; and positive regulation of neuromuscular synaptic transmission. Located in neuromuscular junction; neuron projection; and presynapse. Is an ortholog of human FBXO45 (F-box protein 45). WB:WBGene00001500 ftn-1 Enables identical protein binding activity. Involved in intracellular iron ion homeostasis. Predicted to be located in cytoplasm. Expressed in intestine and pharyngeal-intestinal valve. Human ortholog(s) of this gene implicated in several diseases, including hemochromatosis type 5; hyperferritinemia-cataract syndrome; and neurodegeneration with brain iron accumulation 3. Is an ortholog of human FTH1 (ferritin heavy chain 1); FTHL17 (ferritin heavy chain like 17); and FTMT (ferritin mitochondrial). WB:WBGene00001501 ftn-2 Enables identical protein binding activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in cytoplasm. Expressed in body wall musculature and hypodermis. Human ortholog(s) of this gene implicated in several diseases, including hemochromatosis type 5; hyperferritinemia-cataract syndrome; and neurodegeneration with brain iron accumulation 3. Is an ortholog of human FTMT (ferritin mitochondrial). WB:WBGene00001502 ftt-2 Enables DNA-binding transcription factor binding activity. Involved in cytoplasmic sequestering of protein; dauer larval development; and negative regulation of protein import into nucleus. Located in cytoplasm and nucleus. Expressed in several structures, including C; E; Psub3; gonad; and intestine. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ovarian cancer; and urinary bladder cancer. Is an ortholog of human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) and YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). WB:WBGene00001503 fum-1 Predicted to enable fumarate hydratase activity. Predicted to be involved in fumarate metabolic process; malate metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Human ortholog(s) of this gene implicated in fumarase deficiency and lung non-small cell carcinoma. Is an ortholog of human FH (fumarate hydratase). WB:WBGene00001505 fut-1 Enables 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity and glycoprotein 3-alpha-L-fucosyltransferase activity. Involved in carbohydrate biosynthetic process and fucosylation. Predicted to be located in Golgi membrane. Expressed in chemosensory neurons; pharyngeal-intestinal valve; rectal valve cell; and retrovesicular ganglion. Is an ortholog of human FUT3 (fucosyltransferase 3 (Lewis blood group)); FUT5 (fucosyltransferase 5); and FUT6 (fucosyltransferase 6). WB:WBGene00001506 fut-2 Enables galactoside 2-alpha-L-fucosyltransferase activity. Involved in macromolecule glycosylation. Predicted to be located in Golgi cisterna membrane. Expressed in intestinal cell. WB:WBGene00001507 fut-4 Predicted to enable fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to be located in Golgi cisterna membrane. Is an ortholog of human FUT7 (fucosyltransferase 7). WB:WBGene00001508 fut-8 Enables galactoside 6-L-fucosyltransferase activity and glycoprotein 6-alpha-L-fucosyltransferase activity. Involved in fucosylation and protein N-linked glycosylation. Predicted to be located in Golgi cisterna membrane. Is an ortholog of human FUT8 (fucosyltransferase 8). WB:WBGene00001509 fzo-1 Predicted to enable GTPase activity. Involved in mitochondrial fusion. Predicted to be located in mitochondrial outer membrane. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Charcot-Marie-Tooth disease (multiple); multiple symmetric lipomatosis; and primary pulmonary hypertension. Is an ortholog of human MFN2 (mitofusin 2). WB:WBGene00001510 fzr-1 Predicted to enable anaphase-promoting complex binding activity and ubiquitin-protein transferase activator activity. Involved in cell cycle G1/S phase transition and regulation of cell division. Located in cytoplasm and nucleus. Expressed in intestinal cell; seam cell; ventral cord blast cell; and vulval precursor cell. WB:WBGene00001511 fzy-1 Predicted to enable anaphase-promoting complex binding activity and ubiquitin ligase activator activity. Involved in asymmetric cell division; meiotic cell cycle; and polarity specification of anterior/posterior axis. Located in condensed chromosome and cytoplasm. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 109. Is an ortholog of human CDC20 (cell division cycle 20) and FZR1 (fizzy and cell division cycle 20 related 1). WB:WBGene00001512 gab-1 Enables GABA-A receptor activity and extracellular ligand-gated monoatomic ion channel activity. Involved in monoatomic ion transport. Predicted to be located in neuron projection and synapse. Predicted to be part of GABA-A receptor complex. Expressed in neurons. Human ortholog(s) of this gene implicated in autistic disorder and epilepsy (multiple). Is an ortholog of human GABRB1 (gamma-aminobutyric acid type A receptor subunit beta1) and GABRB2 (gamma-aminobutyric acid type A receptor subunit beta2). WB:WBGene00001513 gad-1 Involved in cell migration involved in gastrulation; establishment of mitotic spindle orientation; and regulation of mitotic cell cycle. Predicted to be located in nucleus and site of double-strand break. Expressed in germ line. Is an ortholog of human WDR70 (WD repeat domain 70). WB:WBGene00001514 xnd-1 Expressed in several structures, including P4; Z2; Z3; germ line; and pharynx. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00001515 gap-1 Predicted to enable GTPase activator activity. Involved in chemosensory behavior; learning or memory; and negative regulation of Ras protein signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Noonan syndrome. Is an ortholog of human RASA3 (RAS p21 protein activator 3). WB:WBGene00001516 gap-2 Predicted to enable GTPase activator activity. Involved in learning or memory and negative regulation of Ras protein signal transduction. Predicted to be located in cytoplasm. Expressed in several structures, including head muscle; head neurons; non-striated muscle; tail; and vulva. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 5; gastrointestinal system cancer (multiple); and lung non-small cell carcinoma. Is an ortholog of human DAB2IP (DAB2 interacting protein); RASAL2 (RAS protein activator like 2); and SYNGAP1 (synaptic Ras GTPase activating protein 1). WB:WBGene00001517 gar-1 Enables G protein-coupled acetylcholine receptor activity. Involved in cholinergic synaptic transmission. Located in postsynaptic membrane. Expressed in PVM and head neurons. WB:WBGene00001518 gar-2 Enables G protein-coupled acetylcholine receptor activity. Involved in G protein-coupled receptor signaling pathway; negative regulation of cholinergic synaptic transmission; and response to xenobiotic stimulus. Located in axon. Expressed in neurons. WB:WBGene00001519 gar-3 Enables G protein-coupled acetylcholine receptor activity. Involved in several processes, including G protein-coupled acetylcholine receptor signaling pathway; positive regulation of acetylcholine secretion, neurotransmission; and positive regulation of protein localization to synapse. Located in plasma membrane. Expressed in body wall musculature; linker cell; neurons; non-striated muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; autoimmune disease of the nervous system (multiple); and lung disease (multiple). Is an ortholog of human CHRM1 (cholinergic receptor muscarinic 1); CHRM3 (cholinergic receptor muscarinic 3); and CHRM5 (cholinergic receptor muscarinic 5). WB:WBGene00001520 gas-1 Predicted to enable several functions, including 4 iron, 4 sulfur cluster binding activity; NAD binding activity; and NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone and response to xenobiotic stimulus. Located in intracellular membrane-bounded organelle. Expressed in anterior gonad arm; body wall musculature; nervous system; non-striated muscle; and tail. Used to study alcohol use disorder and mitochondrial complex I deficiency. Human ortholog(s) of this gene implicated in several diseases, including Leigh disease; multiple sclerosis; and nuclear type mitochondrial complex I deficiency 6. Is an ortholog of human NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2). WB:WBGene00001521 gas-2 No description available WB:WBGene00001522 gbh-1 Predicted to enable gamma-butyrobetaine dioxygenase activity and iron ion binding activity. Predicted to be involved in carnitine biosynthetic process. Predicted to be located in mitochondrion. Is an ortholog of human BBOX1 (gamma-butyrobetaine hydroxylase 1). WB:WBGene00001523 gbh-2 Predicted to enable iron ion binding activity and trimethyllysine dioxygenase activity. Predicted to be involved in carnitine biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human TMLHE (trimethyllysine hydroxylase, epsilon). WB:WBGene00001526 gck-1 Enables mitogen-activated protein kinase binding activity and protein serine/threonine kinase activity. Involved in several processes, including positive regulation of endocytic recycling; regulation of Golgi organization; and regulation of oocyte development. Located in cytoplasm and cytoplasmic side of apical plasma membrane. Used to study cerebral cavernous malformation. Is an ortholog of human STK26 (serine/threonine kinase 26). WB:WBGene00001527 gcs-1 Predicted to enable glutamate-cysteine ligase activity. Involved in several processes, including glutathione biosynthetic process; response to arsenic-containing substance; and response to superoxide. Predicted to be part of glutamate-cysteine ligase complex. Expressed in ASIL; ASIR; intestine; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including colorectal cancer; cystic fibrosis; and glutamate-cysteine ligase deficiency. Is an ortholog of human GCLC (glutamate-cysteine ligase catalytic subunit). WB:WBGene00001528 gcy-1 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in chemosensory behavior; chemotaxis; and response to metal ion. Predicted to be located in plasma membrane. Expressed in PVT; head neurons; and intestine. WB:WBGene00001529 gcy-2 Expressed in PVT and head neurons. WB:WBGene00001530 gcy-3 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Expressed in ASER; ASIL; ASIR; and PVT. WB:WBGene00001531 gcy-4 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in several processes, including chemosensory behavior; chemotaxis; and response to salt. Predicted to be located in plasma membrane. Expressed in ASER. WB:WBGene00001532 gcy-5 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in several processes, including chemosensory behavior; chemotaxis; and response to salt. Located in cilium. Expressed in ASER; amphid neurons; head neurons; and nervous system. WB:WBGene00001533 gcy-6 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in several processes, including chemosensory behavior; positive regulation of calcium-mediated signaling; and response to magnesium ion. Predicted to be located in plasma membrane. Expressed in ASEL. WB:WBGene00001534 gcy-7 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in chemosensory behavior; chemotaxis; and response to magnesium ion. Located in cilium. Expressed in ASEL. WB:WBGene00001535 gcy-8 Enables guanylate cyclase activity. Involved in microvillus organization and response to temperature stimulus. Located in microvillus membrane and neuron projection terminus. Expressed in AFDL and AFDR. WB:WBGene00001536 gcy-9 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in several processes, including cellular response to acidic pH; detection of chemical stimulus; and positive regulation of neuronal action potential. Located in neuronal cell body and non-motile cilium. Expressed in BAGL and BAGR. WB:WBGene00001537 gcy-11 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Expressed in pharyngeal muscle cell. WB:WBGene00001538 gcy-12 Enables guanylate cyclase activity. Involved in negative regulation of dauer larval development; regulation of growth; and regulation of locomotion involved in locomotory behavior. Located in dendrite; non-motile cilium; and perikaryon. Expressed in excretory gland cell; ganglia; head muscle; and head neurons. WB:WBGene00001539 gcy-13 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Expressed in RIML; RIMR; and nervous system. WB:WBGene00001540 gcy-14 Enables identical protein binding activity. Involved in several processes, including chemosensory behavior; response to alkaline pH; and response to lithium ion. Predicted to be located in plasma membrane. Expressed in ASEL; AWCL; AWCR; and PVT. WB:WBGene00001541 gcy-15 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Expressed in ASGL and ASGR. WB:WBGene00001542 gcy-17 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Expressed in PHAL; PHAR; and head. WB:WBGene00001543 gcy-18 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis. Located in microvillus membrane and neuron projection terminus. Expressed in intestine and nervous system. WB:WBGene00001544 gcy-19 Predicted to enable ATP binding activity; guanylate cyclase activity; and protein kinase activity. Predicted to be involved in cGMP biosynthetic process and intracellular signal transduction. Predicted to be located in membrane. Expressed in inner labial neurons and nervous system. WB:WBGene00001545 gcy-20 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Expressed in ASEL; AWCL; AWCR; excretory canal; and excretory gland cell. WB:WBGene00001546 gcy-21 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Expressed in amphid neurons. WB:WBGene00001547 gcy-22 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in several processes, including positive regulation of calcium-mediated signaling; response to metal ion; and response to methionine. Predicted to be located in plasma membrane. Expressed in ASER. WB:WBGene00001548 gcy-23 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis. Located in neuron projection terminus. Expressed in AFDL and AFDR. WB:WBGene00001549 gcy-25 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Expressed in AQR; PQR; URXL; URXR; and neurons. WB:WBGene00001550 gcy-27 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in chemosensory behavior and sensory perception of bitter taste. Predicted to be located in plasma membrane. Expressed in amphid neurons and head mesodermal cell. Human ortholog(s) of this gene implicated in congenital diarrhea 6. Is an ortholog of human GUCY2C (guanylate cyclase 2C). WB:WBGene00001551 gcy-31 Enables oxygen sensor activity. Involved in response to oxygen levels. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Expressed in BAGL; BAGR; and head. WB:WBGene00001552 gcy-32 Predicted to enable guanylate cyclase activity. Predicted to be involved in cGMP-mediated signaling and response to oxygen levels. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Expressed in AQR; PQR; URXL; and URXR. Is an ortholog of human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)). WB:WBGene00001553 gcy-33 Enables carbon monoxide sensor activity; nitric oxide binding activity; and oxygen sensor activity. Involved in chemosensory behavior; response to oxygen levels; and sensory perception of bitter taste. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Expressed in oxygen sensory neurons. WB:WBGene00001554 gcy-34 Predicted to enable guanylate cyclase activity. Involved in chemosensory behavior and sensory perception of bitter taste. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)). WB:WBGene00001555 gcy-35 Enables carbon monoxide binding activity; nitric oxide binding activity; and oxygen sensor activity. Involved in several processes, including aerotaxis; cGMP-mediated signaling; and response to hyperoxia. Located in dendrite and neuronal cell body. Expressed in body wall musculature and pharyngeal muscle cell. Is an ortholog of human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)). WB:WBGene00001556 gcy-36 Enables oxygen sensor activity. Involved in feeding behavior and response to oxygen levels. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)). WB:WBGene00001557 gcy-37 Predicted to enable guanylate cyclase activity. Predicted to be involved in cGMP-mediated signaling and response to oxygen levels. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Is an ortholog of human GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)). WB:WBGene00001558 gdi-1 Predicted to enable Rab GDP-dissociation inhibitor activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Down syndrome; non-syndromic X-linked intellectual disability 41; and psychotic disorder. Is an ortholog of human GDI1 (GDP dissociation inhibitor 1) and GDI2 (GDP dissociation inhibitor 2). WB:WBGene00001559 gei-1 Predicted to enable GTPase activator activity. Predicted to be involved in actin cytoskeleton organization and regulation of Rho protein signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human DLC1 (DLC1 Rho GTPase activating protein); STARD13 (StAR related lipid transfer domain containing 13); and STARD8 (StAR related lipid transfer domain containing 8). WB:WBGene00001560 gei-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head neurons; intestine; and tail neurons. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 45. Is an ortholog of human CIC (capicua transcriptional repressor). WB:WBGene00001561 gei-4 Involved in negative regulation of Ras protein signal transduction and negative regulation of vulval development. WB:WBGene00001562 lin-66 Involved in negative regulation of gene expression and regulation of development, heterochronic. Located in cytoplasm. Expressed in body wall musculature; hypodermis; intestine; neurons; and vulval muscle. WB:WBGene00001563 gei-6 Enriched in OLL; PLM; PVD; and germ line based on microarray and RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and lin-4 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; D-glucose; and bisphenol S based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00001564 icl-1 Predicted to enable isocitrate lyase activity and malate synthase activity. Involved in determination of adult lifespan. Located in mitochondrion. Expressed in hypodermal cell and pharynx. WB:WBGene00001565 gei-8 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including anal depressor muscle; egg-laying apparatus; germ line; somatic nervous system; and tail ganglion. Human ortholog(s) of this gene implicated in Huntington's disease. Is an ortholog of human NCOR1 (nuclear receptor corepressor 1). WB:WBGene00001566 acdh-13 Predicted to enable acyl-CoA dehydrogenase activity. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 20. Is an ortholog of human ACAD9 (acyl-CoA dehydrogenase family member 9). WB:WBGene00001568 snpc-4 Predicted to enable RNA polymerase III type 3 promoter sequence-specific DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in protein folding. Predicted to be located in nucleus. Predicted to be part of snRNA-activating protein complex. Expressed in germ cell; head neurons; intestine; and somatic gonad. Is an ortholog of human SNAPC4 (small nuclear RNA activating complex polypeptide 4). WB:WBGene00001569 meg-3 Involved in embryo development; gamete generation; and organelle localization. Located in P granule. Expressed in several structures, including germ cell and oocyte. WB:WBGene00001570 gei-13 Predicted to enable metal ion binding activity. Predicted to be involved in negative regulation of transcription elongation by RNA polymerase II. Predicted to be part of NELF complex. WB:WBGene00001571 gei-14 Enriched in ABplpappaa; GABAergic neurons; germ line; germline precursor cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including D-glucose; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00001572 gei-15 Located in cell junction and striated muscle dense body. WB:WBGene00001574 gei-17 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and SUMO ligase activity. Involved in several processes, including meiotic metaphase I plate congression; protein sumoylation; and regulation of cellular response to stress. Located in metaphase plate. Part of chromatin. Expressed in motor neurons. Is an ortholog of human PIAS1 (protein inhibitor of activated STAT 1); PIAS2 (protein inhibitor of activated STAT 2); and PIAS3 (protein inhibitor of activated STAT 3). WB:WBGene00001575 gei-18 Predicted to enable ATPase activator activity. Predicted to be involved in membrane organization. Predicted to be located in membrane. Expressed in anterior hypodermis and pharynx. WB:WBGene00001576 gem-3 No description available WB:WBGene00001577 gem-4 Predicted to enable calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion. Predicted to be located in plasma membrane. Expressed in several structures, including Z2; Z3; head mesodermal cell; hermaphrodite gonad; and somatic gonad precursor. Is an ortholog of human CPNE5 (copine 5) and CPNE9 (copine family member 9). WB:WBGene00001578 ges-1 Enables carboxylesterase activity. Involved in cellular catabolic process. Located in peroxisome. Expressed in pharynx. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1). WB:WBGene00001579 gex-2 Predicted to enable RNA 7-methylguanosine cap binding activity. Involved in several processes, including embryonic body morphogenesis; positive regulation of clathrin-dependent endocytosis; and positive regulation of egg-laying behavior. Located in cell junction. Part of SCAR complex. Human ortholog(s) of this gene implicated in several diseases, including Schaaf-Yang syndrome; autism spectrum disorder; and epilepsy (multiple). Is an ortholog of human CYFIP1 (cytoplasmic FMR1 interacting protein 1) and CYFIP2 (cytoplasmic FMR1 interacting protein 2). WB:WBGene00001580 gex-3 Involved in several processes, including egg-laying behavior; embryonic morphogenesis; and positive regulation of cellular component organization. Located in cell junction. Part of SCAR complex. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in immunodeficiency 72. Is an ortholog of human NCKAP1 (NCK associated protein 1). WB:WBGene00001581 gfi-1 Involved in chromatin remodeling. Located in membrane raft. Expressed in I1L; I1R; RIH; and intestine. WB:WBGene00001582 gfi-2 Predicted to enable enzyme inhibitor activity and myosin phosphatase regulator activity. Predicted to be located in cytoplasm. Is an ortholog of human PPP1R16A (protein phosphatase 1 regulatory subunit 16A) and PPP1R16B (protein phosphatase 1 regulatory subunit 16B). WB:WBGene00001583 gfi-3 Predicted to be involved in anaphase-promoting complex-dependent catabolic process and positive regulation of mitotic metaphase/anaphase transition. Predicted to be part of anaphase-promoting complex. Expressed in germ line and sperm. Is an ortholog of human ANAPC5 (anaphase promoting complex subunit 5). WB:WBGene00001584 nrde-4 Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. WB:WBGene00001585 gfl-1 Predicted to enable chromatin binding activity and histone binding activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Is an ortholog of human YEATS4 (YEATS domain containing 4). WB:WBGene00001586 lgc-57 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Predicted to be part of chloride channel complex. Expressed in AIB; nerve ring neurons; and ventral cord neurons. WB:WBGene00001587 lgc-58 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in nerve ring and neurons. WB:WBGene00001588 lgc-56 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in head neurons. WB:WBGene00001589 gip-1 Predicted to enable gamma-tubulin binding activity. Predicted to contribute to microtubule minus-end binding activity. Predicted to be involved in meiotic cell cycle; microtubule cytoskeleton organization; and mitotic cell cycle. Predicted to be located in centrosome and equatorial microtubule organizing center. Predicted to be part of gamma-tubulin complex. WB:WBGene00001590 lipt-1 Predicted to enable lipoyltransferase activity. Predicted to be involved in protein modification process. Predicted to be located in mitochondrion. Is an ortholog of human LIPT1 (lipoyltransferase 1). WB:WBGene00001591 glc-1 Enables extracellularly glutamate-gated chloride channel activity; glutamate binding activity; and identical protein binding activity. Involved in chloride transmembrane transport; locomotion involved in locomotory behavior; and protein complex oligomerization. Located in plasma membrane. Expressed in body wall musculature; head neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in hyperekplexia 1; hyperekplexia 2; and syndromic X-linked intellectual disability Pilgorge type. Is an ortholog of human GLRA2 (glycine receptor alpha 2) and GLRA3 (glycine receptor alpha 3). WB:WBGene00001592 glc-2 Enables extracellularly glutamate-gated chloride channel activity. Involved in chloride transmembrane transport. Located in plasma membrane. Expressed in pm4. Human ortholog(s) of this gene implicated in hyperekplexia 1 and syndromic X-linked intellectual disability Pilgorge type. Is an ortholog of human GLRA1 (glycine receptor alpha 1); GLRA2 (glycine receptor alpha 2); and GLRA3 (glycine receptor alpha 3). WB:WBGene00001593 glc-3 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Involved in locomotion involved in locomotory behavior; sensory perception of chemical stimulus; and sensory processing. Predicted to be located in neuron projection and synapse. Expressed in M4 neuron; head ganglion; and tail neurons. Human ortholog(s) of this gene implicated in hyperekplexia 1 and syndromic X-linked intellectual disability Pilgorge type. Is an ortholog of human GLRA1 (glycine receptor alpha 1); GLRA2 (glycine receptor alpha 2); and GLRA3 (glycine receptor alpha 3). WB:WBGene00001594 glc-4 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in AIYL and AIYR. WB:WBGene00001595 gld-1 Enables mRNA 3'-UTR binding activity; mRNA 5'-UTR binding activity; and single-stranded RNA binding activity. Involved in negative regulation of nitrogen compound metabolic process; oocyte fate determination; and regulation of reproductive process. Located in P granule and cytosol. Expressed in germ line; head neurons; tail neurons; ventral nerve cord; and in male. Is an ortholog of human QKI (QKI, KH domain containing RNA binding). WB:WBGene00001596 gld-2 Enables poly(A) RNA polymerase activity. Involved in several processes, including nucleus organization; positive regulation of meiosis I; and regulation of cell division. Located in P granule and protein-containing complex. Part of RNA-directed RNA polymerase complex. Expressed in germ line and oocyte. Is an ortholog of human TENT2 (terminal nucleotidyltransferase 2). WB:WBGene00001597 gld-3 Enables polynucleotide adenylyltransferase activator activity and protein domain specific binding activity. Involved in several processes, including developmental process involved in reproduction; positive regulation of meiotic nuclear division; and vulval development. Located in P granule. Part of RNA-directed RNA polymerase complex. Expressed in germ line and in male. WB:WBGene00001598 glh-1 Enables RNA helicase activity; enzyme binding activity; and protein self-association. Involved in germ cell development and post-embryonic development. Located in P granule. Expressed in germ line and gonad. Is an ortholog of human DDX4 (DEAD-box helicase 4). WB:WBGene00001599 glh-2 Enables JUN kinase binding activity; RNA helicase activity; and protein self-association. Involved in germ cell development and post-embryonic development. Located in P granule. Expressed in germ line and gonad. Is an ortholog of human DDX4 (DEAD-box helicase 4). WB:WBGene00001600 glh-3 Enables DEAD/H-box RNA helicase binding activity; JUN kinase binding activity; and protein self-association. Predicted to be involved in cell differentiation and gamete generation. Located in P granule. Expressed in gonad. Is an ortholog of human DDX4 (DEAD-box helicase 4). WB:WBGene00001601 glh-4 Enables JUN kinase binding activity. Involved in gamete generation and regulation of cell population proliferation. Located in P granule. WB:WBGene00001602 gln-1 Predicted to enable glutamate-ammonia ligase activity. Predicted to be involved in glutamine biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; schizophrenia; and temporal lobe epilepsy. Is an ortholog of human GLUL (glutamate-ammonia ligase). WB:WBGene00001603 gln-2 Predicted to enable glutamate-ammonia ligase activity. Predicted to be involved in glutamine biosynthetic process. Predicted to be located in cytoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; schizophrenia; and temporal lobe epilepsy. Is an ortholog of human GLUL (glutamate-ammonia ligase). WB:WBGene00001604 gln-3 Predicted to enable glutamate-ammonia ligase activity. Predicted to be involved in glutamine biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; schizophrenia; and temporal lobe epilepsy. Is an ortholog of human GLUL (glutamate-ammonia ligase). WB:WBGene00001605 gln-4 Enriched in germ line and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including methylmercuric chloride; manganese chloride; and stavudine based on microarray and RNA-seq studies. WB:WBGene00001606 gln-5 Predicted to enable glutamate-ammonia ligase activity. Predicted to be involved in glutamine biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; schizophrenia; and temporal lobe epilepsy. Is an ortholog of human GLUL (glutamate-ammonia ligase). WB:WBGene00001607 gln-6 Predicted to enable glutamate-ammonia ligase activity. Predicted to be involved in glutamine biosynthetic process. Predicted to be located in cytoplasm. Expressed in anterior gonad arm and germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; schizophrenia; and temporal lobe epilepsy. Is an ortholog of human GLUL (glutamate-ammonia ligase). WB:WBGene00001608 R07B1.8 Enriched in arc ant V; hyp1; and hyp2 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00001609 glp-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription coactivator activity. Involved in several processes, including cytoplasmic streaming; positive regulation of cell population proliferation; and regulation of gene expression. Located in cytoplasm; endomembrane system; and lateral plasma membrane. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including AB lineage cell; anus; germ line; neurons; and somatic nervous system. Used to study cancer and obesity. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including NOTCH1 (notch receptor 1); NOTCH2 (notch receptor 2); and NOTCH3 (notch receptor 3). WB:WBGene00001612 glr-1 Enables enzyme binding activity and ionotropic glutamate receptor activity. Involved in several processes, including forward locomotion; learning or memory; and positive regulation of locomotion. Located in several cellular components, including perinuclear endoplasmic reticulum; postsynapse; and somatodendritic compartment. Part of ionotropic glutamate receptor complex. Expressed in interneuron; neurons; and ventral nerve cord. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; childhood absence epilepsy; and intellectual disability (multiple). Is an ortholog of human GRIA2 (glutamate ionotropic receptor AMPA type subunit 2) and GRIA3 (glutamate ionotropic receptor AMPA type subunit 3). WB:WBGene00001613 glr-2 Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane. Expressed in DVA; M1 neuron; linker cell; nerve ring; and neurons. Human ortholog(s) of this gene implicated in intellectual disability (multiple) and schizophrenia. Is an ortholog of several human genes including GRIA1 (glutamate ionotropic receptor AMPA type subunit 1); GRIA2 (glutamate ionotropic receptor AMPA type subunit 2); and GRIA3 (glutamate ionotropic receptor AMPA type subunit 3). WB:WBGene00001614 glr-3 Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in detection of cold stimulus involved in thermoception and detection of temperature stimulus involved in sensory perception of pain. Predicted to be located in postsynaptic density membrane. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Is an ortholog of human GRIK3 (glutamate ionotropic receptor kainate type subunit 3) and GRIK4 (glutamate ionotropic receptor kainate type subunit 4). WB:WBGene00001615 glr-4 Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane. Expressed in cholinergic neurons and head neurons. Is an ortholog of human GRIK4 (glutamate ionotropic receptor kainate type subunit 4). WB:WBGene00001616 glr-5 Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane. Expressed in VC neuron and nerve ring neurons. Is an ortholog of human GRIK4 (glutamate ionotropic receptor kainate type subunit 4). WB:WBGene00001617 glr-6 Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane. WB:WBGene00001618 glr-7 Predicted to enable glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 18. Is an ortholog of human GRID1 (glutamate ionotropic receptor delta type subunit 1) and GRID2 (glutamate ionotropic receptor delta type subunit 2). WB:WBGene00001619 glr-8 Predicted to enable ionotropic glutamate receptor activity. Predicted to be involved in ionotropic glutamate receptor signaling pathway and monoatomic ion transmembrane transport. Predicted to be located in plasma membrane. Expressed in head neurons and pharyngeal neurons. WB:WBGene00001620 glt-1 Enables L-glutamate transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport. Located in cell projection. Expressed in body wall musculature; cephalic sheath cell; hypodermis; and muscle cell. Human ortholog(s) of this gene implicated in Huntington's disease; amyotrophic lateral sclerosis; and developmental and epileptic encephalopathy 41. Is an ortholog of human SLC1A2 (solute carrier family 1 member 2). WB:WBGene00001621 glt-3 Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in plasma membrane. Expressed in excretory cell and pharynx. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in Huntington's disease; amyotrophic lateral sclerosis; and developmental and epileptic encephalopathy 41. Is an ortholog of human SLC1A2 (solute carrier family 1 member 2). WB:WBGene00001622 glt-4 Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in plasma membrane. Expressed in head neurons and metacorpus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); dicarboxylic aminoaciduria; and neurodegenerative disease (multiple). Is an ortholog of human SLC1A1 (solute carrier family 1 member 1) and SLC1A6 (solute carrier family 1 member 6). WB:WBGene00001623 glt-5 Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in plasma membrane. Expressed in pharynx. Human ortholog(s) of this gene implicated in Huntington's disease; amyotrophic lateral sclerosis; and developmental and epileptic encephalopathy 41. Is an ortholog of human SLC1A2 (solute carrier family 1 member 2). WB:WBGene00001624 glt-6 Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in plasma membrane. Expressed in marginal cell. Human ortholog(s) of this gene implicated in Huntington's disease; amyotrophic lateral sclerosis; and developmental and epileptic encephalopathy 41. Is an ortholog of human SLC1A2 (solute carrier family 1 member 2). WB:WBGene00001625 glt-7 Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport. Predicted to be located in plasma membrane. Expressed in excretory canal. Human ortholog(s) of this gene implicated in Huntington's disease; amyotrophic lateral sclerosis; and developmental and epileptic encephalopathy 41. Is an ortholog of human SLC1A2 (solute carrier family 1 member 2). WB:WBGene00001626 gly-1 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. Expressed in pharyngeal neurons and seam cell. Is an ortholog of several human genes including GCNT1 (glucosaminyl (N-acetyl) transferase 1); GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type); and GCNT4 (glucosaminyl (N-acetyl) transferase 4). WB:WBGene00001627 gly-2 Enables calmodulin binding activity and hexosyltransferase activity. Involved in protein N-linked glycosylation. Located in nucleus. Expressed in hermaphrodite gonad; neurons; pharyngeal-intestinal valve; pm8; and somatic nervous system. Is an ortholog of human MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase) and MGAT5B (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B). WB:WBGene00001628 gly-3 Enables polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi apparatus. Expressed in hypodermis; intestine; rectal gland cell; and reproductive system. Is an ortholog of human GALNT1 (polypeptide N-acetylgalactosaminyltransferase 1). WB:WBGene00001629 gly-4 Enables polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Is an ortholog of human GALNT2 (polypeptide N-acetylgalactosaminyltransferase 2). WB:WBGene00001630 gly-5 Enables polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human GALNT12 (polypeptide N-acetylgalactosaminyltransferase 12); GALNT4 (polypeptide N-acetylgalactosaminyltransferase 4); and POC1B-GALNT4 (POC1B-GALNT4 readthrough). WB:WBGene00001631 gly-6 Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in Golgi apparatus. WB:WBGene00001632 gly-7 Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in Golgi apparatus. Is an ortholog of human GALNT7 (polypeptide N-acetylgalactosaminyltransferase 7). WB:WBGene00001633 gly-8 Predicted to enable Notch binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in regulation of Notch signaling pathway. Predicted to be located in Golgi apparatus. Is an ortholog of human GALNT11 (polypeptide N-acetylgalactosaminyltransferase 11) and GALNTL5 (polypeptide N-acetylgalactosaminyltransferase like 5). WB:WBGene00001635 gly-10 Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in Golgi apparatus. Is an ortholog of human GALNTL6 (polypeptide N-acetylgalactosaminyltransferase like 6). WB:WBGene00001636 gly-11 Predicted to enable Notch binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in regulation of Notch signaling pathway. Predicted to be located in Golgi apparatus. Expressed in excretory cell; hypodermis; and pharyngeal cell. Is an ortholog of human GALNT11 (polypeptide N-acetylgalactosaminyltransferase 11). WB:WBGene00001637 gly-12 Enables alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity. Involved in protein N-linked glycosylation. Located in perinuclear region of cytoplasm. Expressed in body wall musculature; ganglia; hypodermis; and intestine. Is an ortholog of human MGAT1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase). WB:WBGene00001638 gly-13 Predicted to enable alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity. Predicted to be involved in protein N-linked glycosylation. Located in perinuclear region of cytoplasm. Expressed in several structures, including ganglia; intestine; muscle cell; ventral nerve cord; and vulva. Is an ortholog of human MGAT1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase). WB:WBGene00001639 gly-14 Enables alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity. Involved in protein N-linked glycosylation. Located in perinuclear region of cytoplasm. Is an ortholog of human MGAT1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase). WB:WBGene00001640 gly-15 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in cataract 13 with adult i phenotype. Is an ortholog of several human genes including GCNT1 (glucosaminyl (N-acetyl) transferase 1); GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type); and GCNT4 (glucosaminyl (N-acetyl) transferase 4). WB:WBGene00001641 gly-16 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. Expressed in seam cell. Human ortholog(s) of this gene implicated in cataract 13 with adult i phenotype. Is an ortholog of several human genes including GCNT1 (glucosaminyl (N-acetyl) transferase 1); GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type); and GCNT4 (glucosaminyl (N-acetyl) transferase 4). WB:WBGene00001642 gly-17 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in cataract 13 with adult i phenotype. Is an ortholog of several human genes including GCNT1 (glucosaminyl (N-acetyl) transferase 1); GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type); and GCNT4 (glucosaminyl (N-acetyl) transferase 4). WB:WBGene00001643 gly-18 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. Expressed in several structures, including GLR; distal tip cell; enteric muscle; ventral nerve cord; and vm1. Human ortholog(s) of this gene implicated in cataract 13 with adult i phenotype. Is an ortholog of several human genes including GCNT1 (glucosaminyl (N-acetyl) transferase 1); GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type); and GCNT4 (glucosaminyl (N-acetyl) transferase 4). WB:WBGene00001644 gly-19 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. Expressed in anal sphincter muscle and intestine. Human ortholog(s) of this gene implicated in cataract 13 with adult i phenotype. Is an ortholog of several human genes including GCNT1 (glucosaminyl (N-acetyl) transferase 1); GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type); and GCNT4 (glucosaminyl (N-acetyl) transferase 4). WB:WBGene00001645 gly-20 Predicted to enable alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity. Involved in protein N-linked glycosylation. Predicted to be located in Golgi membrane. Used to study carbohydrate metabolic disorder. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIa. Is an ortholog of human MGAT2 (alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase). WB:WBGene00001646 gna-1 Predicted to enable glucosamine 6-phosphate N-acetyltransferase activity and monosaccharide binding activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. Is an ortholog of human GNPNAT1 (glucosamine-phosphate N-acetyltransferase 1). WB:WBGene00001647 gna-2 Predicted to enable glucosamine 6-phosphate N-acetyltransferase activity and monosaccharide binding activity. Involved in chitin biosynthetic process and eggshell formation. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human GNPNAT1 (glucosamine-phosphate N-acetyltransferase 1). WB:WBGene00001648 goa-1 Enables several functions, including G protein activity; G protein-coupled acetylcholine receptor activity; and GTP binding activity. Involved in several processes, including detection of cold stimulus involved in thermoception; negative regulation of cholinergic synaptic transmission; and response to monoamine. Located in cell cortex. Expressed in several structures, including neurons; non-striated muscle; pharynx; spermatheca; and vulva. Used to study developmental and epileptic encephalopathy and early infantile epileptic encephalopathy. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 17 and neurodevelopmental disorder with involuntary movements. Is an ortholog of human GNAO1 (G protein subunit alpha o1). WB:WBGene00001649 gob-1 Enables trehalose-phosphatase activity. Involved in carbohydrate derivative catabolic process; dephosphorylation; and trehalose biosynthetic process. Located in cytoplasm. Expressed in several structures, including body wall musculature; head neurons; intestine; pharynx; and tail. WB:WBGene00001650 gon-1 Enables metallopeptidase activity. Involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; muscle organ morphogenesis; and negative regulation of presynapse assembly. Predicted to be located in extracellular matrix. Expressed in amphid neurons; excretory cell; gonad; motor neurons; and muscle cell. Used to study obesity and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Is an ortholog of human ADAMTS20 (ADAM metallopeptidase with thrombospondin type 1 motif 20) and ADAMTS9 (ADAM metallopeptidase with thrombospondin type 1 motif 9). WB:WBGene00001651 gon-2 Predicted to enable monoatomic cation channel activity. Involved in defecation; gonad development; and mitotic cell cycle. Predicted to be located in plasma membrane. Expressed in gonad and intestine. Human ortholog(s) of this gene implicated in several diseases, including amyotrophic lateral sclerosis-parkinsonism/dementia complex 1; congenital stationary night blindness 1C; and intestinal hypomagnesemia 1. Is an ortholog of human TRPM3 (transient receptor potential cation channel subfamily M member 3) and TRPM7 (transient receptor potential cation channel subfamily M member 7). WB:WBGene00001652 gon-3 No description available WB:WBGene00001653 gon-4 Predicted to enable transcription coregulator activity. Involved in gonad development and positive regulation of cell division. Located in germ cell nucleus. Expressed in germ line and gonad. Is an ortholog of human GON4L (gon-4 like) and YY1AP1 (YY1 associated protein 1). WB:WBGene00001654 gon-5 No description available WB:WBGene00001655 gon-6 No description available WB:WBGene00001656 gon-7 No description available WB:WBGene00001657 gon-8 No description available WB:WBGene00001658 gon-9 No description available WB:WBGene00001659 gon-11 No description available WB:WBGene00001660 gop-1 Predicted to be involved in endosomal transport; endosome to lysosome transport; and regulation of autophagosome maturation. Predicted to be located in endolysosome membrane and late endosome. Expressed in coelomocyte; intestinal cell; non-striated muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in Addison's disease and autoimmune disease (multiple). Is an ortholog of human CLEC16A (C-type lectin domain containing 16A). WB:WBGene00001661 gop-2 Predicted to enable GTPase activity. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human GPN1 (GPN-loop GTPase 1). WB:WBGene00001662 gop-3 Predicted to be involved in mitochondrial respiratory chain complex assembly and protein insertion into mitochondrial outer membrane. Predicted to be located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease. Is an ortholog of human SAMM50 (SAMM50 sorting and assembly machinery component). WB:WBGene00001663 gpa-1 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Expressed in several structures, including SPD; chemosensory neurons; head mesodermal cell; pharyngeal neurons; and postcloacal sensillum. WB:WBGene00001664 gpa-2 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium; olfactory learning; and positive regulation of gene expression. Located in axon; neuronal cell body; and non-motile cilium. Expressed in anal sphincter muscle; ganglia; and pharyngeal cell. WB:WBGene00001665 gpa-3 Enables olfactory receptor binding activity. Involved in several processes, including cellular response to cGMP; regulation of gene expression; and signal transduction. Located in axon; neuronal cell body; and non-motile cilium. Expressed in AWAL; AWAR; AWCL; and AWCR. WB:WBGene00001666 gpa-4 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Located in non-motile cilium. Expressed in several structures, including P lineage cell; body wall musculature; neurons; somatic gonad; and vulval precursor cell. Human ortholog(s) of this gene implicated in achromatopsia 4; congenital stationary night blindness 1G; and congenital stationary night blindness autosomal dominant 3. Is an ortholog of human GNAI1 (G protein subunit alpha i1). WB:WBGene00001667 gpa-5 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway and phospholipase C-activating dopamine receptor signaling pathway. Located in axon; neuronal cell body; and synapse. Expressed in amphid neurons. WB:WBGene00001668 gpa-6 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Located in axon and neuronal cell body. Expressed in ciliated neurons and head mesodermal cell. WB:WBGene00001669 gpa-7 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Located in cytosol and nucleus. Expressed in head; muscle cell; neurons; tail; and in male. WB:WBGene00001670 gpa-8 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Expressed in AQR; PQR; URXL; URXR; and head. WB:WBGene00001671 gpa-9 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Expressed in ASJ; lumbar neurons; pharyngeal muscle cell; and spermatheca. WB:WBGene00001672 gpa-10 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in short-term memory. Predicted to be part of heterotrimeric G-protein complex. Expressed in neurons and spermatheca. WB:WBGene00001673 gpa-11 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in determination of adult lifespan and serotonin receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Expressed in SMD and chemosensory neurons. WB:WBGene00001674 gpa-12 Predicted to enable D5 dopamine receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in antifungal innate immune response and positive regulation of gene expression. Located in cytoplasm and nucleus. Expressed in several structures, including excretory cell; intestine; nerve ring; neurons; and pharynx. Is an ortholog of human GNA12 (G protein subunit alpha 12) and GNA13 (G protein subunit alpha 13). WB:WBGene00001675 gpa-13 Enables G-protein alpha-subunit binding activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Located in axon; neuronal cell body; and non-motile cilium. Expressed in RIH and ciliated neurons. WB:WBGene00001676 gpa-14 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Expressed in neurons and vulval muscle. WB:WBGene00001677 gpa-15 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Located in non-motile cilium. Expressed in chemosensory neurons and hermaphrodite somatic gonadal cell. WB:WBGene00001678 gpa-16 Predicted to enable several functions, including G-protein beta/gamma-subunit complex binding activity; GTPase activity; and guanyl ribonucleotide binding activity. Involved in embryonic axis specification and establishment of mitotic spindle orientation. Located in cell cortex. Expressed in several structures, including Psub4; Z2; Z3; neurons; and pharynx. Human ortholog(s) of this gene implicated in achromatopsia 4; congenital stationary night blindness 1G; and congenital stationary night blindness autosomal dominant 3. Is an ortholog of human GNAI1 (G protein subunit alpha i1). WB:WBGene00001679 gpb-1 Predicted to enable signaling receptor complex adaptor activity. Involved in several processes, including establishment of mitotic spindle orientation; negative regulation of locomotion; and regulation of egg-laying behavior. Predicted to be located in cytoplasm. Predicted to be part of heterotrimeric G-protein complex. Expressed in several structures, including body wall musculature; germ line; intestine; pharynx; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease dominant intermediate F; artery disease (multiple); and hematologic cancer (multiple). Is an ortholog of human GNB1 (G protein subunit beta 1) and GNB4 (G protein subunit beta 4). WB:WBGene00001680 gpb-2 Predicted to enable signaling receptor complex adaptor activity. Involved in several processes, including cellular response to organonitrogen compound; regulation of egg-laying behavior; and regulation of pharyngeal pumping. Located in neuronal cell body. Expressed in body wall musculature; neurons; pharyngeal muscle cell; and vulval muscle. Human ortholog(s) of this gene implicated in intellectual developmental disorder with cardiac arrhythmia. Is an ortholog of human GNB5 (G protein subunit beta 5). WB:WBGene00001681 gpc-1 Predicted to enable G-protein beta-subunit binding activity. Involved in sensory perception of taste. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Expressed in RIB; amphid neurons; and phasmid neurons. Is an ortholog of human GNG7 (G protein subunit gamma 7). WB:WBGene00001682 gpc-2 Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Expressed in muscle cell and neurons. Is an ortholog of human GNG13 (G protein subunit gamma 13). WB:WBGene00001683 gpd-1 Predicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). WB:WBGene00001684 gpd-2 Predicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in several structures, including AB; Psub1; and head. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). WB:WBGene00001685 gpd-3 Predicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in several structures, including gonad; intestine; and pharynx. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). WB:WBGene00001686 gpd-4 Predicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). WB:WBGene00001687 gpn-1 Involved in several processes, including epidermis morphogenesis; nematode larval development; and neuron migration. Predicted to be located in cell surface. Expressed in neuroblasts and ventral cord neurons. Human ortholog(s) of this gene implicated in Keipert syndrome; hepatocellular carcinoma; and omodysplasia 1. Is an ortholog of several human genes including GPC1 (glypican 1); GPC4 (glypican 4); and GPC6 (glypican 6). WB:WBGene00001688 gpr-1 Enables G-protein alpha-subunit binding activity and GDP-dissociation inhibitor activity. Predicted to be involved in cell division. Located in aster and cell cortex. Expressed in P lineage cell. WB:WBGene00001689 gpr-2 Enables GDP-dissociation inhibitor activity. Predicted to be involved in cell division. Located in aster and cell cortex. Expressed in P lineage cell. WB:WBGene00001690 grd-1 Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in extracellular region. WB:WBGene00001691 grd-2 Predicted to enable cholesterol binding activity; endopeptidase activity; and signaling receptor binding activity. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in extracellular region. Expressed in excretory duct and excretory pore. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); gastrointestinal system cancer (multiple); and glomerulonephritis (multiple). Is an ortholog of human DHH (desert hedgehog signaling molecule); IHH (Indian hedgehog signaling molecule); and SHH (sonic hedgehog signaling molecule). WB:WBGene00001692 grd-3 Predicted to enable signaling receptor binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular region. WB:WBGene00001693 grd-4 Enriched in RME; dopaminergic neurons; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-three chemicals including cholesterol; lathosterol; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001694 grd-5 Predicted to enable signaling receptor binding activity. Involved in embryo development. Predicted to be located in extracellular region. Expressed in anterior arcade cell; pharyngeal neurons; rectal epithelium; and vulval cell. WB:WBGene00001695 grd-6 Expressed in excretory duct and excretory pore. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001696 grd-7 Predicted to enable signaling receptor binding activity. Predicted to be involved in cell communication. Predicted to be located in extracellular region. Expressed in seam cell. WB:WBGene00001697 grd-8 Acts upstream of or within nematode male tail mating organ morphogenesis. Expressed in OLLL and OLLR. WB:WBGene00001698 grd-9 Acts upstream of or within nematode male tail mating organ morphogenesis. WB:WBGene00001699 grd-10 Enriched in several structures, including ABalppppaa; PLM; germ line; non-striated muscle; and somatic nervous system based on Chronogram; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including nicotinic acid; rotenone; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001700 grd-11 Predicted to be involved in protein autoprocessing. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); gastrointestinal system cancer (multiple); and glomerulonephritis (multiple). Is an ortholog of human DHH (desert hedgehog signaling molecule); IHH (Indian hedgehog signaling molecule); and SHH (sonic hedgehog signaling molecule). WB:WBGene00001701 grd-12 Expressed in head; tail; and vulC. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001702 grd-13 Expressed in intestine; isthmus; metacorpus; procorpus; and rectal epithelium. WB:WBGene00001703 grd-14 Expressed in rectal epithelium. WB:WBGene00001704 grd-15 Enriched in arc ant V based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including mianserin; Zidovudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001705 grd-16 Enriched in hyp3 and interfacial epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00001706 grd-17 Is affected by several genes including eat-2; clk-1; and npr-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including rotenone; D-glucose; and metformin based on RNA-seq studies. WB:WBGene00001707 grh-1 Enables sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 28 and posterior polymorphous corneal dystrophy 4. Is an ortholog of human GRHL1 (grainyhead like transcription factor 1); GRHL2 (grainyhead like transcription factor 2); and GRHL3 (grainyhead like transcription factor 3). WB:WBGene00001708 grk-1 Predicted to enable protein kinase activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including Oguchi disease-2; essential hypertension; and rheumatoid arthritis. Is an ortholog of human GRK5 (G protein-coupled receptor kinase 5) and GRK6 (G protein-coupled receptor kinase 6). WB:WBGene00001709 grk-2 Predicted to enable G protein-coupled receptor binding activity and G protein-coupled receptor kinase activity. Involved in several processes, including positive regulation of egg-laying behavior; positive regulation of growth rate; and serotonin catabolic process. Expressed in neurons and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including bacterial pneumonia; rheumatoid arthritis; and toxic shock syndrome. Is an ortholog of human GRK2 (G protein-coupled receptor kinase 2) and GRK3 (G protein-coupled receptor kinase 3). WB:WBGene00001710 grl-1 Expressed in lumbar ganglion and tail. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001711 grl-2 Expressed in head. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001712 grl-3 Enriched in PLM; Z1; Z4; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001713 grl-4 Expressed in anterior arcade cell; head; hypodermis; and vulval cell. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001714 grl-5 Expressed in hypodermal cell; hypodermis; rectal epithelium; and ventral cord blast cell. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001715 grl-6 Expressed in PVT. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001716 grl-7 Located in apical plasma membrane. Expressed in hypodermal cell and ventral cord blast cell. WB:WBGene00001717 grl-8 Expressed in rectal epithelium. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001718 grl-9 Expressed in terminal bulb. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001719 grl-10 Expressed in tail; vulA; vulB1; and vulB2. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001720 grl-11 Expressed in pm6. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001721 grl-12 Expressed in AMsoL and AMsoR. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001722 grl-13 Enriched in AVA; I5 neuron; RIAL; RIAR; and dopaminergic neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including clk-1; sek-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001723 grl-14 Expressed in anterior arcade cell. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001724 grl-15 Expressed in vulB1; vulB2; vulC; vulD; and vulE. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001725 grl-16 Enriched in several structures, including arc ant V; germ line; hypodermis; neurons; and rectal epithelial cell based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-four chemicals including hydrogen sulfide; 1-methylnicotinamide; and nicotinic acid based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001726 grl-17 Expressed in head and terminal bulb. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001727 grl-18 Enriched in GABAergic neurons and accessory cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; glp-1; and let-60 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Rifampin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001728 grl-19 Expressed in excretory duct and excretory pore. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001729 grl-20 Enriched in AVK; dopaminergic neurons; head neurons; and rectal epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including cholesterol; lathosterol; and methylmercuric chloride based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001730 grl-21 Enriched in ABplpapppa; anterior ganglion; germline precursor cell; interfacial epithelial cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; quantitative PCR; tiling array; and RNA-seq studies. Is affected by twenty-eight chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001731 grl-22 Enriched in Cappppv; Cpppppv; hypodermis; and tail hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001732 grl-23 Enriched in AVK; FLP; and neurons based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00001733 grl-24 Enriched in hypodermis based on tiling array studies. Is affected by several genes including sir-2.1; alg-1; and mex-3 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including methylmercury hydroxide; methylmercuric chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001734 grl-25 Predicted to be located in cytoplasm. Expressed in intestine; nervous system; and reproductive system. WB:WBGene00001735 grl-26 Expressed in anterior arcade cell and posterior arcade cell. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001736 grl-27 Expressed in anterior arcade cell; head; posterior arcade cell; and seam cell. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001737 grl-28 Expressed in AMshL and AMshR. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001738 grl-29 Expressed in rectal epithelium. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001739 grl-30 Is affected by several genes including daf-12; aak-2; and dcr-1 based on microarray and RNA-seq studies. Is affected by bortezomib based on RNA-seq studies. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00001740 gro-1 Predicted to enable tRNA dimethylallyltransferase activity. Involved in determination of adult lifespan and regulation of growth. Located in mitochondrion and nucleus. Expressed widely. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 35. Is an ortholog of human TRIT1 (tRNA isopentenyltransferase 1). WB:WBGene00001741 gro-2 No description available WB:WBGene00001742 gro-3 No description available WB:WBGene00001743 grp-1 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Located in midbody and nucleus. Expressed in somatic cell. Is an ortholog of human CYTH4 (cytohesin 4). WB:WBGene00001744 gars-1 Predicted to enable glycine-tRNA ligase activity and protein dimerization activity. Predicted to be involved in diadenosine tetraphosphate biosynthetic process and mitochondrial glycyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2D and distal hereditary motor neuronopathy type 5A. Is an ortholog of human GARS1 (glycyl-tRNA synthetase 1). WB:WBGene00001745 gsa-1 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in several processes, including negative regulation of protein kinase C signaling; pharyngeal pumping; and positive regulation of oocyte maturation. Predicted to be located in membrane. Predicted to be part of heterotrimeric G-protein complex. Expressed in several structures, including excretory cell; intestine; neurons; non-striated muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including ACTH-independent macronodular adrenal hyperplasia 1; Alzheimer's disease; dystonia 25; and pseudohypoparathyroidism (multiple). Is an ortholog of human GNAL (G protein subunit alpha L). WB:WBGene00001746 gsk-3 Enables protein serine/threonine kinase activity. Involved in several processes, including engulfment of apoptotic cell; left/right axis specification; and regulation of cellular component organization. Predicted to be located in cytosol and nucleus. Expressed in distal tip cell; seam cell; and sperm. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; bipolar disorder; carcinoma (multiple); and degenerative disc disease. Is an ortholog of human GSK3A (glycogen synthase kinase 3 alpha) and GSK3B (glycogen synthase kinase 3 beta). WB:WBGene00001747 gsp-1 Predicted to enable protein serine/threonine phosphatase activity. Involved in negative regulation of protein phosphorylation and positive regulation of gene expression. Predicted to be located in cytoplasm and nucleus. Expressed in oocyte. Human ortholog(s) of this gene implicated in Noonan syndrome-like disorder with loose anagen hair 2. Is an ortholog of human PPP1CB (protein phosphatase 1 catalytic subunit beta). WB:WBGene00001748 gsp-2 Enables protein serine/threonine phosphatase activity. Predicted to be involved in cell division; chromatin organization; and meiotic cell cycle. Located in chromosome; cytoplasm; and nuclear membrane. Expressed in body wall musculature; gonad; intestine; nervous system; and oocyte. Is an ortholog of human PPP1CA (protein phosphatase 1 catalytic subunit alpha). WB:WBGene00001749 gst-1 Enables glutathione transferase activity. Involved in cellular detoxification; defense response to other organism; and regulation of cellular response to manganese ion. Predicted to be located in cytosol. Expressed in DA neuron. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). WB:WBGene00001750 gst-2 Predicted to enable glutathione transferase activity. Expressed in head. WB:WBGene00001751 gst-3 Predicted to enable glutathione transferase activity. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001752 gst-4 Enables glutathione transferase activity. Involved in glutathione metabolic process. Located in contractile fiber. Expressed in body wall musculature; hypodermis; muscle cell; and pharynx. WB:WBGene00001753 gst-5 Predicted to enable glutathione transferase activity. Involved in innate immune response. Expressed in intestine and nerve ring. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001754 gst-6 Predicted to enable glutathione transferase activity. Involved in innate immune response. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001755 gst-7 Predicted to enable glutathione transferase activity. Involved in innate immune response. Expressed in germ line; head; and hypodermis. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001756 gst-8 Predicted to enable glutathione transferase activity. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001757 gst-9 Predicted to enable glutathione transferase activity. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001758 gst-10 Enables glutathione transferase activity. Involved in several processes, including determination of adult lifespan; heat acclimation; and response to UV-C. Predicted to be located in cytosol. Expressed in head and tail. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). WB:WBGene00001759 gst-11 Enriched in ABaraapapaa; ABaraapppaa; head mesodermal cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Human HPGDS enables metal ion binding activity; prostaglandin-D synthase activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001760 gst-12 Enriched in several structures, including ABarpaapap; ABarpaappa; germ line; neuronal sheath cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. WB:WBGene00001761 gst-13 Involved in innate immune response. WB:WBGene00001762 gst-14 Predicted to enable transferase activity. Expressed in intestine and pharynx. WB:WBGene00001763 gst-15 Enriched in head mesodermal cell; neurons; and pharyngeal muscle cell based on tiling array; RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by twenty chemicals including Mercuric Chloride; stavudine; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. WB:WBGene00001764 gst-16 Enriched in several structures, including germ line; interfacial epithelial cell; interneuron; male distal tip cell; and rectal gland cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by twenty-five chemicals including Heme; hydrogen sulfide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. WB:WBGene00001765 gst-17 Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal domain; and Glutathione S-transferase, C-terminal. WB:WBGene00001766 gst-18 Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal domain; Thioredoxin-like superfamily; and Glutathione S-transferase, C-terminal. WB:WBGene00001767 gst-19 Enriched in several structures, including AVH; Caaaaa; Caaaap; Caaapa; and pm6 based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twenty chemicals including Heme; hydrogen sulfide; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. WB:WBGene00001768 gst-20 Predicted to enable glutathione transferase activity. Involved in determination of adult lifespan. Predicted to be located in cytoplasm. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001769 gst-21 Enriched in hypodermis; neuronal sheath cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on RNA-seq and microarray studies. Is affected by twenty-five chemicals including tryptophan; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. WB:WBGene00001770 gst-22 Enriched in several structures, including cephalic sheath cell; head mesodermal cell; intestine; muscle cell; and rectal gland cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Heme; 1-methylnicotinamide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. WB:WBGene00001771 gst-23 Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). WB:WBGene00001772 gst-24 Involved in innate immune response. Expressed in head and tail. WB:WBGene00001773 gst-25 Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). WB:WBGene00001774 gst-26 Enriched in g1; head mesodermal cell; intestine; mechanosensory neurons; and muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty chemicals including glutathione; rotenone; and Tunicamycin based on proteomic; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. WB:WBGene00001775 gst-27 Enriched in PVP; arcade cell; head mesodermal cell; intestine; and mechanosensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including glutathione; nicotinic acid; and rotenone based on proteomic; RNA-seq; and microarray studies. Human HPGDS enables metal ion binding activity; prostaglandin-D synthase activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001776 gst-28 Enriched in several structures, including GABAergic neurons; excretory cell; head mesodermal cell; neuronal sheath cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including glutathione; 25-azacoprostane; and methylmercury hydroxide based on proteomic; RNA-seq; and microarray studies. Human HPGDS enables metal ion binding activity; prostaglandin-D synthase activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001777 gst-29 Enriched in muscle cell; neurons; and retrovesicular ganglion based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including Heme; Zidovudine; and Sodium Chloride based on microarray and RNA-seq studies. Human HPGDS enables metal ion binding activity; prostaglandin-D synthase activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001778 gst-30 Expressed in head; tail; and vulva. Human HPGDS enables metal ion binding activity; prostaglandin-D synthase activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001779 gst-31 Enriched in anterior hypodermis; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by twenty chemicals including 1-methylnicotinamide; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. WB:WBGene00001780 gst-32 Involved in response to reactive oxygen species. WB:WBGene00001781 gst-33 Expressed in tail. Human HPGDS enables metal ion binding activity; prostaglandin-D synthase activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001782 gst-34 Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including juglone; metformin; and Sirolimus based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Human GSTA1 enables several functions, including glutathione peroxidase activity; glutathione transferase activity; and steroid delta-isomerase activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3). WB:WBGene00001783 gst-35 Predicted to enable transferase activity. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3). WB:WBGene00001784 gst-36 Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in obsolete oxidation-reduction process. WB:WBGene00001785 gst-37 Expressed in gonad; head; and tail. Human HPGDS enables metal ion binding activity; prostaglandin-D synthase activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001786 gst-38 Predicted to enable transferase activity. Involved in PERK-mediated unfolded protein response and innate immune response. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001787 gst-39 Enriched in g1; head mesodermal cell; intestine; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including glutathione; methylmercuric chloride; and rotenone based on proteomic; microarray; and RNA-seq studies. Human HPGDS enables metal ion binding activity; prostaglandin-D synthase activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). WB:WBGene00001788 gst-40 Enriched in enteric muscle; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including aldicarb; D-glucose; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. WB:WBGene00001789 gst-41 Predicted to enable transferase activity. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). WB:WBGene00001790 gst-42 Enables identical protein binding activity. Predicted to be involved in L-phenylalanine catabolic process and glutathione metabolic process. Predicted to be located in mitochondrion. Expressed in intestine. Is an ortholog of human GSTZ1 (glutathione S-transferase zeta 1). WB:WBGene00001791 gst-43 Predicted to enable glutathione transferase activity and maleylacetoacetate isomerase activity. Predicted to be involved in L-phenylalanine catabolic process and glutathione metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human GSTZ1 (glutathione S-transferase zeta 1). WB:WBGene00001792 gst-44 Predicted to enable glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Involved in response to reactive oxygen species. Predicted to be located in cytoplasm. Expressed in excretory cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Is an ortholog of human GSTO1 (glutathione S-transferase omega 1) and GSTO2 (glutathione S-transferase omega 2). WB:WBGene00001793 gsy-1 Predicted to enable glycogen (starch) synthase activity. Predicted to be involved in glycogen biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in cardiovascular system disease and glycogen storage disease. Is an ortholog of human GYS1 (glycogen synthase 1) and GYS2 (glycogen synthase 2). WB:WBGene00001794 gta-1 Predicted to enable 4-aminobutyrate transaminase activity and pyridoxal phosphate binding activity. Predicted to be involved in gamma-aminobutyric acid catabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease; GABA aminotransferase deficiency; and Huntington's disease. Is an ortholog of human ABAT (4-aminobutyrate aminotransferase). WB:WBGene00001795 gtl-1 Predicted to enable monoatomic cation channel activity. Involved in defecation. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1; cataract; and congenital stationary night blindness 1C. Is an ortholog of human TRPM1 (transient receptor potential cation channel subfamily M member 1); TRPM3 (transient receptor potential cation channel subfamily M member 3); and TRPM7 (transient receptor potential cation channel subfamily M member 7). WB:WBGene00001796 gtl-2 Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Located in basal plasma membrane. Expressed in excretory canal; excretory cell; hypodermis; pharyngeal muscle cell; and pharynx. Used to study MASA syndrome. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1; cataract; and congenital stationary night blindness 1C. Is an ortholog of human TRPM1 (transient receptor potential cation channel subfamily M member 1); TRPM3 (transient receptor potential cation channel subfamily M member 3); and TRPM7 (transient receptor potential cation channel subfamily M member 7). WB:WBGene00001798 gum-2 No description available WB:WBGene00001799 gum-3 No description available WB:WBGene00001800 gum-4 No description available WB:WBGene00001801 gum-5 No description available WB:WBGene00001802 gum-6 No description available WB:WBGene00001803 lite-1 Enables blue light photoreceptor activity. Involved in locomotory behavior and response to light stimulus. Located in neuron projection; neuronal cell body; and plasma membrane. Expressed in ganglia; hyp3; and pharyngeal neurons. WB:WBGene00001804 gur-3 Predicted to be involved in sensory perception of taste. Located in nucleus. Expressed in AVDL; AVDR; I2L; I2R; and I4 neuron. WB:WBGene00001805 gur-4 Predicted to be located in membrane. WB:WBGene00001806 gur-5 Predicted to be located in membrane. WB:WBGene00001807 gus-1 No description available WB:WBGene00001808 gut-2 Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in P-body. Predicted to be part of Lsm1-7-Pat1 complex and ribonucleoprotein complex. Is an ortholog of human LSM2 (LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated). WB:WBGene00001809 gut-4 No description available WB:WBGene00001810 hab-1 No description available WB:WBGene00001811 haf-1 Enables peptide transmembrane transporter activity. Involved in mitochondrial unfolded protein response; peptide transport; and protein import into mitochondrial matrix. Located in mitochondrial inner membrane. Is an ortholog of human ABCB10 (ATP binding cassette subfamily B member 10). WB:WBGene00001812 haf-2 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be located in membrane. Expressed in intestine and muscle cell. Is an ortholog of human ABCB9 (ATP binding cassette subfamily B member 9). WB:WBGene00001813 haf-3 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in intestine and spermatheca. Is an ortholog of human ABCB10 (ATP binding cassette subfamily B member 10). WB:WBGene00001814 haf-4 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in lipid metabolic process and lysosomal transport. Located in lysosomal membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); bronchial disease (multiple); and lung disease (multiple). Is an ortholog of human ABCB9 (ATP binding cassette subfamily B member 9). WB:WBGene00001815 hmt-1 Enables cadmium ion transmembrane transporter activity. Involved in cadmium ion transmembrane transport; cellular detoxification of cadmium ion; and detoxification of copper ion. Located in endosome and vacuolar membrane. Expressed in coelomocyte; head neurons; intestinal cell; and tail neurons. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Is an ortholog of human ABCB6 (ATP binding cassette subfamily B member 6 (Langereis blood group)). WB:WBGene00001816 haf-6 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in perinuclear endoplasmic reticulum. Expressed in germ line; intestine; and muscle cell. Is an ortholog of human ABCB8 (ATP binding cassette subfamily B member 8). WB:WBGene00001817 haf-7 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); bronchial disease (multiple); and systemic scleroderma (multiple). Is an ortholog of human TAP2 (transporter 2, ATP binding cassette subfamily B member). WB:WBGene00001818 haf-8 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); bronchial disease (multiple); and systemic scleroderma (multiple). Is an ortholog of human ABCB9 (ATP binding cassette subfamily B member 9); TAP1 (transporter 1, ATP binding cassette subfamily B member); and TAP2 (transporter 2, ATP binding cassette subfamily B member). WB:WBGene00001819 haf-9 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in lysosomal transport and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in lysosomal membrane. Is an ortholog of human ABCB9 (ATP binding cassette subfamily B member 9). WB:WBGene00001820 ham-1 Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including generation of neurons; protein localization; and spindle localization. Located in cell cortex and nucleus. Expressed in neuroblasts. Human ortholog(s) of this gene implicated in Alzheimer's disease and pre-eclampsia. Is an ortholog of human STOX1 (storkhead box 1). WB:WBGene00001821 ham-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in cell fate determination; cell migration; and regulation of neuron differentiation. Located in nucleus. WB:WBGene00001823 hap-1 Predicted to enable nucleoside triphosphate diphosphatase activity. Predicted to be involved in nucleoside triphosphate catabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including developmental and epileptic encephalopathy 35; hepatitis C; and rheumatoid arthritis. Is an ortholog of human ITPA (inosine triphosphatase). WB:WBGene00001824 hbl-1 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; negative regulation of transcription by RNA polymerase II; and nematode larval development. Located in nucleus. Expressed in several structures, including body wall musculature; germ line; hypodermis; neurons; and ventral nerve cord. WB:WBGene00001825 hcd-1 No description available WB:WBGene00001826 hcd-2 No description available WB:WBGene00001827 hcf-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; transcription coregulator activity; and transcription coregulator binding activity. Involved in several processes, including dauer exit; determination of adult lifespan; and regulation of DNA-templated transcription. Acts upstream of or within defense response to other organism and response to endoplasmic reticulum stress. Located in nucleus. Part of transcription regulator complex. Expressed widely. Human ortholog(s) of this gene implicated in methylmalonic acidemia and homocysteinemia cblX type. Is an ortholog of human HCFC1 (host cell factor C1) and HCFC2 (host cell factor C2). WB:WBGene00001828 hch-1 Predicted to enable metalloendopeptidase activity. Involved in hatching and neuron migration. Predicted to be located in extracellular region. Expressed in hypodermis and seam cell. WB:WBGene00001829 hcp-1 Involved in chromosome segregation; organelle organization; and protein localization. Located in kinetochore; nucleus; and spindle. Expressed in AB and Psub1. WB:WBGene00001830 hcp-2 Predicted to enable actin filament binding activity and microfilament motor activity. Involved in chromosome segregation; meiotic spindle organization; and protein localization. Located in kinetochore. WB:WBGene00001831 hcp-3 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in several processes, including negative regulation of mitotic centrosome separation; non-membrane-bounded organelle assembly; and protein localization to chromosome. Located in kinetochore and nucleus. Expressed in embryonic cell; hyp3; hyp4; hyp7 syncytium; and seam cell. WB:WBGene00001832 hcp-4 Involved in several processes, including kinetochore assembly; negative regulation of mitotic centrosome separation; and nuclear chromosome segregation. Located in cytoplasm; kinetochore; and nucleoplasm. WB:WBGene00001833 hcp-6 Predicted to enable histone binding activity. Involved in attachment of mitotic spindle microtubules to kinetochore; embryo development; and mitotic chromosome condensation. Located in condensed chromosome, centromeric region and nucleoplasm. Part of condensin complex. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Is an ortholog of human NCAPD3 (non-SMC condensin II complex subunit D3). WB:WBGene00001834 hda-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and histone deacetylase activity. Contributes to transcription corepressor activity. Involved in several processes, including developmental process involved in reproduction; negative regulation of signal transduction; and regulation of transcription by RNA polymerase II. Acts upstream of or within chromatin organization; determination of adult lifespan; and mitochondrial unfolded protein response. Located in cytoplasm and germ cell nucleus. Part of NuRD complex. Expressed in anchor cell; germ line; nervous system; tail; and vulva. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); and prostate disease (multiple). Is an ortholog of human HDAC1 (histone deacetylase 1) and HDAC2 (histone deacetylase 2). WB:WBGene00001835 hda-2 Predicted to enable histone deacetylase activity and transcription corepressor activity. Involved in DNA protection and nematode male tail tip morphogenesis. Predicted to be located in nucleus. Predicted to be part of histone deacetylase complex. Expressed in distal tip cell; gonadal sheath cell; nerve ring; pharynx; and uterus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); intrahepatic cholestasis of pregnancy; and pulmonary hypertension. Is an ortholog of human HDAC3 (histone deacetylase 3). WB:WBGene00001836 hda-3 Predicted to enable histone deacetylase activity and transcription corepressor activity. Involved in DNA protection. Located in nucleus. Expressed in several structures, including ASHL and ASHR. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); and prostate disease (multiple). Is an ortholog of human HDAC1 (histone deacetylase 1) and HDAC2 (histone deacetylase 2). WB:WBGene00001837 hda-4 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of transcription by RNA polymerase II; receptor guanylyl cyclase signaling pathway; and regulation of neuron differentiation. Located in nucleus. Expressed in amphid neurons; body wall musculature; motor neurons; seam cell; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); gastrointestinal system cancer (multiple); and neurodegenerative disease (multiple). Is an ortholog of several human genes including HDAC4 (histone deacetylase 4); HDAC5 (histone deacetylase 5); and HDAC9 (histone deacetylase 9). WB:WBGene00001838 hda-10 Predicted to enable histone deacetylase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be part of histone deacetylase complex. Is an ortholog of human HDAC10 (histone deacetylase 10). WB:WBGene00001839 hdl-1 Predicted to enable carboxy-lyase activity. Predicted to be involved in amino acid metabolic process and dopamine biosynthetic process. Predicted to be located in cytoplasm. WB:WBGene00001840 hel-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in determination of adult lifespan; nuclear mRNA surveillance; and positive regulation of gene expression. Located in nucleus. Part of transcription regulator complex. Expressed in hypodermis; intestine; and neurons. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Is an ortholog of human DDX39A (DExD-box helicase 39A). WB:WBGene00001841 hen-1 Predicted to enable transmembrane receptor protein tyrosine kinase activator activity. Involved in dauer larval development and nervous system process. Located in axon and neuronal cell body. Expressed in neurons; pharyngeal muscle cell; and vulva. WB:WBGene00001842 her-1 Enables signaling receptor binding activity. Involved in male sex determination. Located in extracellular region. WB:WBGene00001843 hgo-1 Predicted to enable homogentisate 1,2-dioxygenase activity. Predicted to be involved in L-phenylalanine catabolic process. Located in striated muscle dense body. Expressed in body wall musculature and vulval muscle. Human ortholog(s) of this gene implicated in alkaptonuria. Is an ortholog of human HGD (homogentisate 1,2-dioxygenase). WB:WBGene00001844 hid-1 Involved in several processes, including cellular response to carbon dioxide; defecation; and negative regulation of pharyngeal pumping. Located in several cellular components, including Golgi cisterna; cytosol; and neuron projection. Expressed in intestine; nervous system; and uv1. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 105. Is an ortholog of human HID1 (HID1 domain containing). WB:WBGene00001845 hid-2 Acts upstream of or within dauer larval development and response to heat. WB:WBGene00001846 hid-3 No description available WB:WBGene00001847 hid-4 Acts upstream of or within dauer larval development and response to heat. WB:WBGene00001848 hid-5 No description available WB:WBGene00001849 hid-6 No description available WB:WBGene00001850 hid-7 No description available WB:WBGene00001851 hif-1 Enables DNA-binding transcription factor activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including cellular response to caloric restriction; determination of adult lifespan; and heat acclimation. Located in nucleus. Expressed widely. Used to study cancer. Human ortholog(s) of this gene implicated in several diseases, including arthritis (multiple); familial erythrocytosis 4; and hypertension (multiple). Is an ortholog of human EPAS1 (endothelial PAS domain protein 1) and HIF3A (hypoxia inducible factor 3 subunit alpha). WB:WBGene00001852 hil-1 Predicted to enable double-stranded DNA binding activity and nucleosomal DNA binding activity. Involved in several processes, including body morphogenesis; egg-laying behavior; and pharynx development. Located in intermediate filament cytoskeleton and nucleolus. Expressed in several structures, including body wall musculature; excretory system; head neurons; marginal cell; and vulval muscle. WB:WBGene00001853 hil-2 Predicted to enable double-stranded DNA binding activity and nucleosomal DNA binding activity. Predicted to be involved in chromosome condensation and negative regulation of DNA recombination. Predicted to be located in nucleus. Predicted to be part of nucleosome. Is an ortholog of human H1-8 (H1.8 linker histone). WB:WBGene00001854 hil-3 Predicted to enable double-stranded DNA binding activity and nucleosomal DNA binding activity. Predicted to be involved in chromosome condensation and negative regulation of DNA recombination. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed widely. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Is an ortholog of human H1-8 (H1.8 linker histone). WB:WBGene00001855 hil-4 Predicted to enable double-stranded DNA binding activity and nucleosomal DNA binding activity. Predicted to be involved in chromosome condensation and negative regulation of DNA recombination. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed in several structures, including somatic cell. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Is an ortholog of human H1-8 (H1.8 linker histone). WB:WBGene00001856 hil-5 Predicted to enable double-stranded DNA binding activity and nucleosomal DNA binding activity. Predicted to be involved in chromosome condensation and negative regulation of DNA recombination. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed widely. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Is an ortholog of human H1-8 (H1.8 linker histone). WB:WBGene00001857 hil-6 Predicted to enable double-stranded DNA binding activity and nucleosomal DNA binding activity. Predicted to be involved in chromosome condensation and negative regulation of DNA recombination. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed widely. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Is an ortholog of human H1-8 (H1.8 linker histone). WB:WBGene00001858 hil-7 Predicted to enable DNA binding activity. Predicted to be a structural constituent of chromatin. Predicted to be involved in nucleosome assembly. Predicted to be part of nucleosome. Expressed widely. WB:WBGene00001859 hil-8 Predicted to enable DNA binding activity. Predicted to be involved in nucleosome assembly. Predicted to be part of nucleosome. WB:WBGene00001860 him-1 Enables DNA binding activity. Involved in chromosome segregation; embryo development; and response to radiation. Located in nucleus. Part of chromatin and cohesin complex. Expressed in linker cell. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 2; congestive heart failure; and developmental and epileptic encephalopathy 85. Is an ortholog of human SMC1B (structural maintenance of chromosomes 1B). WB:WBGene00001861 him-2 No description available WB:WBGene00001862 him-3 Enables DNA binding activity. Involved in regulation of centriole-centriole cohesion and synaptonemal complex assembly. Located in lateral element. Expressed in oocyte and spermatocyte. Is an ortholog of human HORMAD1 (HORMA domain containing 1) and HORMAD2 (HORMA domain containing 2). WB:WBGene00001863 him-4 An extracellular matrix structural constituent. Involved in basement membrane disassembly. Located in basement membrane. Expressed in body wall musculature; germ cell; germ line; gonad; and pharynx. Human ortholog(s) of this gene implicated in age related macular degeneration 1. Is an ortholog of human HMCN1 (hemicentin 1). WB:WBGene00001864 him-5 Involved in meiotic DNA double-strand break formation involved in reciprocal meiotic recombination and meiotic chromosome segregation. Located in condensed chromosome. Expressed in gonad. WB:WBGene00001865 him-6 Enables 3'-5' DNA helicase activity and enzyme binding activity. Involved in several processes, including determination of adult lifespan; meiotic nuclear division; and resolution of recombination intermediates. Located in chromosome and nucleus. Used to study Bloom syndrome. Human ortholog(s) of this gene implicated in Bloom syndrome. Is an ortholog of human BLM (BLM RecQ like helicase). WB:WBGene00001866 him-7 No description available WB:WBGene00001867 him-8 Involved in meiotic chromosome segregation. Located in X chromosome; condensed nuclear chromosome; and nuclear envelope. WB:WBGene00001869 him-10 Predicted to enable structural molecule activity. Involved in nuclear chromosome segregation and organelle organization. Located in kinetochore. Part of Ndc80 complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and oral cavity carcinoma in situ. Is an ortholog of human NUF2 (NUF2 component of NDC80 kinetochore complex). WB:WBGene00001870 him-11 No description available WB:WBGene00001871 him-13 No description available WB:WBGene00001872 him-14 Predicted to enable double-stranded DNA binding activity. Involved in chiasma assembly; embryo development; and resolution of meiotic recombination intermediates. Located in nucleus. Expressed in embryonic cell and gonad. Human ortholog(s) of this gene implicated in primary ovarian insufficiency and spermatogenic failure 2. Is an ortholog of human MSH4 (mutS homolog 4). WB:WBGene00001874 him-17 Involved in germline cell cycle switching, mitotic to meiotic cell cycle and resolution of meiotic recombination intermediates. Part of chromatin. Expressed in germ line; head; and tail. WB:WBGene00001875 his-1 Predicted to enable DNA binding activity. Predicted to be involved in nucleosome assembly. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001876 his-2 Enables methylated histone binding activity. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001877 his-3 Predicted to enable DNA binding activity. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001878 his-4 Predicted to enable DNA binding activity. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001879 his-5 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001880 his-6 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001881 his-7 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001882 his-8 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001883 his-9 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Expressed in several structures, including MI neuron and e3D. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001884 his-10 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in defense response to Gram-negative bacterium and innate immune response. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001885 his-11 Predicted to enable DNA binding activity. Involved in innate immune response. Part of chromatin. Is an ortholog of several human genes including H2BC12 (H2B clustered histone 12); H2BC17 (H2B clustered histone 17); and H2BC3 (H2B clustered histone 3). WB:WBGene00001886 his-12 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001887 his-13 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001888 his-14 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001889 his-15 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in innate immune response. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC12 (H2B clustered histone 12); H2BC17 (H2B clustered histone 17); and H2BC3 (H2B clustered histone 3). WB:WBGene00001890 his-16 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001891 his-17 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001892 his-18 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001893 his-19 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001894 his-20 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001895 his-21 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001896 his-22 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001898 his-24 Enables H3K27me3 modified histone binding activity. Involved in defense response to Gram-positive bacterium and negative regulation of gene expression. Located in chromosome, telomeric region; cytoplasm; and nucleus. Expressed in several structures, including germ line and gonad. Is an ortholog of human H1-0 (H1.0 linker histone) and H1-8 (H1.8 linker histone). WB:WBGene00001899 his-25 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001900 his-26 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in positive regulation of transcription by RNA polymerase II. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001901 his-27 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001902 his-28 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001903 his-29 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC12 (H2B clustered histone 12); H2BC17 (H2B clustered histone 17); and H2BC3 (H2B clustered histone 3). WB:WBGene00001904 his-30 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001905 his-31 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001906 his-32 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001907 his-33 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001908 his-34 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in innate immune response. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC12 (H2B clustered histone 12); H2BC17 (H2B clustered histone 17); and H2BC3 (H2B clustered histone 3). WB:WBGene00001909 his-35 Predicted to enable DNA binding activity. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001910 C50F4.6 Enriched in several structures, including GLR; MSpppaaa; germ line; head mesodermal cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including mianserin; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00001911 his-37 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001912 his-38 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in positive regulation of transcription by RNA polymerase II. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001913 his-39 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of human H2BK1 (H2B.K variant histone 1). WB:WBGene00001914 his-40 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001915 his-41 Predicted to enable DNA binding activity. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001916 his-42 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001917 his-43 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in innate immune response. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001918 his-44 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in innate immune response. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC12 (H2B clustered histone 12); H2BC17 (H2B clustered histone 17); and H2BC3 (H2B clustered histone 3). WB:WBGene00001919 his-45 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001920 his-46 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001921 his-47 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001922 his-48 Predicted to enable DNA binding activity. Involved in innate immune response. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Expressed in gonad. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001923 his-49 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001924 his-50 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001925 his-51 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001926 his-52 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001927 his-53 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001928 his-54 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001929 his-55 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001930 his-56 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001931 his-57 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001932 his-58 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Expressed in sperm and spermatid. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001933 his-59 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001934 his-60 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001935 his-61 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Expressed in somatic cell. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001936 his-62 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001937 his-63 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4). WB:WBGene00001938 his-64 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in positive regulation of transcription by RNA polymerase II. Expressed in head; somatic cell; and tail. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001939 his-65 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001940 his-66 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H2BC3 (H2B clustered histone 3); H2BC5 (H2B clustered histone 5); and H2BC8 (H2B clustered histone 8). WB:WBGene00001941 his-67 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in positive regulation of transcription by RNA polymerase II. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). WB:WBGene00001942 his-68 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone). WB:WBGene00001943 his-69 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in nucleus. Predicted to be part of nucleosome. WB:WBGene00001944 his-70 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed in sperm. Is an ortholog of human H3Y1 (H3.Y histone 1) and H3Y2 (H3.Y histone 2). WB:WBGene00001945 his-71 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed in several structures, including somatic cell. Is an ortholog of human H3-3A (H3.3 histone A) and H3-3B (H3.3 histone B). WB:WBGene00001946 his-72 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Located in nucleus. Part of nucleosome. Expressed in several structures, including germ cell; somatic cell; and in male. Is an ortholog of human H3-3A (H3.3 histone A) and H3-3B (H3.3 histone B). WB:WBGene00001947 his-73 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. WB:WBGene00001948 hlh-1 Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Involved in positive regulation of mesodermal cell fate specification; positive regulation of transcription by RNA polymerase II; and striated muscle cell differentiation. Acts upstream of or within positive regulation of muscle cell differentiation. Located in nucleus. Expressed in several structures, including C lineage cell; D lineage cell; I4 neuron; MSaaaapa; and body wall muscle cell. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in congenital myopathy 17 and congenital structural myopathy. Is an ortholog of several human genes including MYF5 (myogenic factor 5); MYF6 (myogenic factor 6); and MYOD1 (myogenic differentiation 1). WB:WBGene00001949 hlh-2 Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; bHLH transcription factor binding activity; and protein dimerization activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including generation of neurons; regulation of metabolic process; and sex differentiation. Located in cytoplasm and nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including distal tip cell; enteric muscle; lateral ganglion; ray precursor cell; and terminal bulb. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including Fuchs' endothelial dystrophy; Pitt-Hopkins syndrome; and agammaglobulinemia (multiple). Is an ortholog of human TCF12 (transcription factor 12); TCF3 (transcription factor 3); and TCF4 (transcription factor 4). WB:WBGene00001950 hlh-3 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein heterodimerization activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including regulation of axon extension involved in axon guidance; regulation of egg-laying behavior; and response to food. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including AB lineage cell; ABplapppapp; ABplpapaaa; nerve ring; and neurons. Is an ortholog of human ASCL1 (achaete-scute family bHLH transcription factor 1). WB:WBGene00001951 hlh-4 Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and bHLH transcription factor binding activity. Involved in positive regulation of transcription by RNA polymerase II and response to food. Part of RNA polymerase II transcription regulator complex. Expressed in ABalppppaav; ABpraaapaav; ADLL; and ADLR. WB:WBGene00001952 hlh-6 Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including pharyngeal gland morphogenesis; positive regulation of eating behavior; and positive regulation of pharynx morphogenesis. Located in cell projection and nucleus. Is an ortholog of human ASCL3 (achaete-scute family bHLH transcription factor 3). WB:WBGene00001953 hlh-8 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in mesodermal cell fate specification; positive regulation of transcription by RNA polymerase II; and vulval cell fate specification. Predicted to be located in nucleus. Expressed in several structures, including M.dla; M.dra; M.vla; body wall muscle cell from M lineage; and enteric muscle. Used to study Saethre-Chotzen syndrome. Human ortholog(s) of this gene implicated in several diseases, including Barber-Say syndrome; Sweeney-Cox syndrome; and synostosis (multiple). Is an ortholog of human TWIST2 (twist family bHLH transcription factor 2). WB:WBGene00001954 hlh-10 Enables protein heterodimerization activity and transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Expressed in ADLL; ADLR; ASEL; ASER; and neurons. Human ortholog(s) of this gene implicated in coronary artery disease and ventricular septal defect. Is an ortholog of human MSC (musculin) and TCF21 (transcription factor 21). WB:WBGene00001955 hlh-11 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including excretory cell; intestinal cell; male-specific anatomical entity; non-striated muscle; and somatic nervous system. Is an ortholog of human TFAP4 (transcription factor AP-4). WB:WBGene00001956 hlh-12 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in gonad morphogenesis; positive regulation of distal tip cell migration; and positive regulation of gene expression. Located in nucleus. Expressed in anterior distal tip cell; distal tip cell; linker cell; and posterior distal tip cell. Is an ortholog of human FERD3L (Fer3 like bHLH transcription factor). WB:WBGene00001957 hlh-13 Enables DNA-binding transcription factor binding activity. Involved in dauer exit and response to oxidative stress. Predicted to be located in nucleus. Expressed in neurons. Is an ortholog of human FERD3L (Fer3 like bHLH transcription factor). WB:WBGene00001958 hlh-14 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; generation of neurons; and positive regulation of growth rate. Located in nucleus. Expressed in several structures, including ABplapppaap; ABplapppapa; ABprapppaap; ABprapppapa; and neurons. WB:WBGene00001959 hlh-15 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in positive regulation of DNA-templated transcription. Acts upstream of or within determination of adult lifespan. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism. Is an ortholog of human NHLH2 (nescient helix-loop-helix 2). WB:WBGene00001960 hlh-16 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Involved in neuron projection development. Predicted to be located in nucleus. Expressed in ABplpapaaa; ABplpapaap; ABprpapaaa; ABprpapaap; and ventral ganglion. WB:WBGene00001961 hlh-17 Predicted to enable DNA-binding transcription factor activity and E-box binding activity. Involved in positive regulation of dopaminergic synaptic transmission and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in CEPshDL; CEPshDR; CEPshVL; CEPshVR; and ventral cord neurons. Is an ortholog of human BHLHE22 (basic helix-loop-helix family member e22) and BHLHE23 (basic helix-loop-helix family member e23). WB:WBGene00001962 hlh-19 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. WB:WBGene00001963 btb-1 Enriched in germ line based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and unc-30 based on microarray and RNA-seq studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00001964 hlh-25 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including dauer exit; determination of adult lifespan; and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including MSpa; anal depressor muscle; body wall musculature; intestinal cell; and neurons. WB:WBGene00001965 hlh-26 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ABpla; ABplp; ABpra; and ABprp. WB:WBGene00001966 hlh-27 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including ABpla; ABplp; ABprp; MSaa; and MSpa. WB:WBGene00001967 hlh-28 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including E; Ea; Ep; MSa; and MSp. WB:WBGene00001968 hlh-29 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including amphid sheath cell; coelomocyte; ganglia; non-striated muscle; and rectal gland cell. WB:WBGene00001969 hlp-1 No description available WB:WBGene00001970 hlp-2 No description available WB:WBGene00001971 hmg-1.1 Predicted to enable transcription cis-regulatory region binding activity. Predicted to be located in nucleus. Expressed in head neurons; pharynx; tail neurons; ventral nerve cord; and vulva. WB:WBGene00001972 hmg-1.2 Enables transcription cis-regulatory region binding activity. Involved in several processes, including gonad development; positive regulation of transcription by RNA polymerase II; and vulval development. Located in nucleus. Expressed in several structures, including tail. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; cerebral infarction; and syndromic microphthalmia 13. Is an ortholog of human HMGB3 (high mobility group box 3). WB:WBGene00001973 hmg-3 Predicted to enable histone binding activity and nucleosome binding activity. Involved in pharynx development and regulation of embryonic development. Located in nucleus. Is an ortholog of human SSRP1 (structure specific recognition protein 1). WB:WBGene00001974 hmg-4 Predicted to enable histone binding activity and nucleosome binding activity. Involved in pharynx development and regulation of embryonic development. Located in nucleus. Expressed in several structures, including coelomocyte; head muscle; neurons; somatic cell; and somatic nervous system. Is an ortholog of human SSRP1 (structure specific recognition protein 1). WB:WBGene00001975 hmg-5 Enables identical protein binding activity and telomeric DNA binding activity. Involved in mitochondrial DNA metabolic process. Located in chromosome, telomeric region and mitochondrial nucleoid. Expressed in dorsal nerve cord; head muscle; head neurons; oocyte; and ventral nerve cord. Human ortholog(s) of this gene implicated in Alzheimer's disease; mitochondrial DNA depletion syndrome 15; and obesity. Is an ortholog of human TFAM (transcription factor A, mitochondrial). WB:WBGene00001976 hmg-11 Predicted to enable DNA binding activity. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including Silver-Russell syndrome; leiomyoma; and ovarian cancer. Is an ortholog of human HMGA2 (high mobility group AT-hook 2). WB:WBGene00001977 hmg-12 Enables RNA polymerase II core promoter sequence-specific DNA binding activity. Involved in positive regulation of gene expression. Predicted to be located in nucleus. WB:WBGene00001978 hmp-1 Enables actin filament binding activity and beta-catenin binding activity. Involved in several processes, including cortical actin cytoskeleton organization; embryonic morphogenesis; and regulation of actin cytoskeleton organization. Located in adherens junction and apical junction complex. Part of catenin complex. Expressed in several structures, including distal tip cell; germ cell; intestinal cell; neuroblasts; and pharyngeal cell. Human ortholog(s) of this gene implicated in several diseases, including arrhythmogenic right ventricular dysplasia 13; cervix uteri carcinoma in situ; and urinary system cancer (multiple). Is an ortholog of human CTNNA2 (catenin alpha 2). WB:WBGene00001979 hmp-2 Enables several functions, including alpha-catenin binding activity; cadherin binding activity; and transcription coactivator activity. Involved in several processes, including cytoskeleton organization; embryonic morphogenesis; and left/right axis specification. Located in adherens junction and nucleus. Part of catenin complex. Expressed in distal tip cell and germ cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; gastrointestinal system cancer (multiple); germ cell cancer (multiple); and urinary system cancer (multiple). Is an ortholog of human JUP (junction plakoglobin). WB:WBGene00001980 hmr-1 Enables beta-catenin binding activity and delta-catenin binding activity. Involved in cytoskeleton organization; embryo development; and gastrulation. Located in adherens junction; distal dendrite; and plasma membrane. Part of catenin complex. Expressed in several structures, including germline precursor cell; hypodermis; motor neurons; nerve ring; and neuroblasts. WB:WBGene00001981 hnd-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in gonad development. Acts upstream of or within gonadal mesoderm development and positive regulation of muscle cell differentiation. Predicted to be located in nucleus. Expressed in several structures, including Daa; Dap; Dpa; Dpp; and somatic gonad precursor. Is an ortholog of human HAND1 (heart and neural crest derivatives expressed 1). WB:WBGene00001982 hnl-1 No description available WB:WBGene00001983 hoe-1 Predicted to enable 3'-tRNA processing endoribonuclease activity. Involved in nematode larval development; positive regulation of vulval development; and sexual reproduction. Predicted to be located in mitochondrion. Expressed in germ line. Used to study prostate cancer. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 17. Is an ortholog of human ELAC2 (elaC ribonuclease Z 2). WB:WBGene00001984 hog-1 Predicted to be involved in protein autoprocessing. Predicted to be located in extracellular region. Expressed in rectal epithelium. WB:WBGene00001985 hop-1 Predicted to enable endopeptidase activity. Involved in several processes, including egg-laying behavior; positive regulation of Notch signaling pathway; and regulation of vulval development. Predicted to be located in several cellular components, including apical plasma membrane; cytoplasm; and plasma membrane bounded cell projection. WB:WBGene00001986 hot-1 Predicted to be involved in olfactory behavior and response to odorant. Predicted to be located in axon and neuronal cell body. WB:WBGene00001987 hot-2 Predicted to be involved in olfactory behavior and response to odorant. Predicted to be located in axon and neuronal cell body. WB:WBGene00001988 hot-3 Predicted to be involved in olfactory behavior and response to odorant. Predicted to be located in axon and neuronal cell body. WB:WBGene00001989 hot-4 Predicted to be involved in olfactory behavior and response to odorant. Predicted to be located in axon and neuronal cell body. Expressed in head and tail. WB:WBGene00001990 hot-5 Predicted to be involved in olfactory behavior and response to odorant. Predicted to be located in axon and neuronal cell body. WB:WBGene00001991 hot-6 Predicted to be located in membrane. WB:WBGene00001992 hot-7 Enriched in CEP socket cell; enteric muscle; head mesodermal cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; lin-35; and daf-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including nicotinic acid; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00001993 hpd-1 Predicted to enable 4-hydroxyphenylpyruvate dioxygenase activity. Predicted to be involved in tyrosine catabolic process. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hawkinsinuria and tyrosinemia type III. Is an ortholog of human HPD (4-hydroxyphenylpyruvate dioxygenase). WB:WBGene00001994 hpk-1 Predicted to enable protein serine/threonine kinase activity and protein tyrosine kinase activity. Involved in several processes, including autophagosome assembly; determination of adult lifespan; and response to heat. Located in nucleus. Expressed in several structures, including gonad and neurons. Used to study Parkinson's disease. Is an ortholog of human HIPK1 (homeodomain interacting protein kinase 1); HIPK2 (homeodomain interacting protein kinase 2); and HIPK3 (homeodomain interacting protein kinase 3). WB:WBGene00001995 hpl-1 Enables enzyme binding activity and methylated histone binding activity. Involved in several processes, including developmental process involved in reproduction; negative regulation of vulval development; and positive regulation of growth rate. Located in nucleus. Part of heterochromatin. Expressed in several structures, including neurons. Human ortholog(s) of this gene implicated in lung adenocarcinoma and prostate cancer. Is an ortholog of human CBX3 (chromobox 3). WB:WBGene00001996 hpl-2 Enables H3K27me3 modified histone binding activity and chromatin binding activity. Involved in several processes, including developmental process involved in reproduction; nematode larval development; and regulation of gene expression. Located in nuclear periphery. Expressed in several structures, including AWCL; AWCR; hyp7 syncytium; and vulval precursor cell. WB:WBGene00001997 hpr-9 Predicted to be involved in DNA integrity checkpoint signaling; DNA repair; and cellular response to ionizing radiation. Predicted to be located in nucleus. Predicted to be part of checkpoint clamp complex. Is an ortholog of human RAD9B (RAD9 checkpoint clamp component B). WB:WBGene00001998 hpr-17 Predicted to enable chromatin binding activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in DNA damage checkpoint signaling; DNA repair; and mitotic DNA replication checkpoint signaling. Predicted to be located in nucleus. Is an ortholog of human RAD17 (RAD17 checkpoint clamp loader component). WB:WBGene00001999 hrpa-1 Predicted to enable mRNA 3'-UTR binding activity. Involved in hemidesmosome assembly. Located in chromosome, telomeric region. Expressed in several structures, including germ line. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; amyotrophic lateral sclerosis type 20; carcinoma (multiple); and inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 2. Is an ortholog of human HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1) and HNRNPA3 (heterogeneous nuclear ribonucleoprotein A3). WB:WBGene00002000 hrpr-1 Predicted to enable mRNA binding activity. Located in nucleus. Expressed widely. Is an ortholog of human HNRNPR (heterogeneous nuclear ribonucleoprotein R) and SYNCRIP (synaptotagmin binding cytoplasmic RNA interacting protein). WB:WBGene00002001 hars-1 Predicted to enable RNA binding activity; histidine-tRNA ligase activity; and identical protein binding activity. Involved in germ cell development; nematode larval development; and translation. Predicted to be located in cytosol and mitochondrion. Used to study Perrault syndrome and sensory peripheral neuropathy. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease, axonal type 2W; Perrault syndrome; and Usher syndrome type 3B. Is an ortholog of human HARS1 (histidyl-tRNA synthetase 1) and HARS2 (histidyl-tRNA synthetase 2, mitochondrial). WB:WBGene00002002 hsb-1 Predicted to enable transcription corepressor activity. Predicted to be involved in cellular heat acclimation. Predicted to be located in cytosol and nucleus. Is an ortholog of human HSBP1 (heat shock factor binding protein 1). WB:WBGene00002003 hse-5 Predicted to enable heparosan-N-sulfate-glucuronate 5-epimerase activity. Involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification; regulation of cell migration; and regulation of growth. Predicted to be located in Golgi apparatus. Expressed in hypodermis. Human ortholog(s) of this gene implicated in cerebrovascular disease and hypertension. Is an ortholog of human GLCE (glucuronic acid epimerase). WB:WBGene00002004 hsf-1 Enables several functions, including DNA-binding transcription factor activity; calmodulin binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including ascaroside biosynthetic process; defense response to other organism; and positive regulation of metabolic process. Located in cytoplasm; nuclear body; and nuclear stress granule. Part of chromatin. Expressed in several structures, including germ cell; hypodermis; intestine; neurons; and somatic cell. Human ortholog(s) of this gene implicated in Huntington's disease and cataract 5 multiple types. Is an ortholog of human HSF1 (heat shock transcription factor 1) and HSF2 (heat shock transcription factor 2). WB:WBGene00002005 hsp-1 Enables ATP hydrolysis activity. Involved in determination of adult lifespan; response to heat; and retrograde transport, endosome to Golgi. Located in cytosol and nucleus. Expressed in germ line and intestine. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); brain disease (multiple); and eye disease (multiple). Is an ortholog of human HSPA8 (heat shock protein family A (Hsp70) member 8). WB:WBGene00002006 hsp-2 Enriched in germ line based on proteomic studies. Is affected by several genes including daf-16; lin-4; and eat-2 based on proteomic; microarray; and RNA-seq studies. Is affected by seven chemicals including metformin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00002007 hsp-3 Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum lumen; membrane; and nucleus. Predicted to be part of endoplasmic reticulum chaperone complex. Expressed in several structures, including germ line; hypodermis; intestinal muscle; pharyngeal-intestinal valve; and tail. Human ortholog(s) of this gene implicated in several diseases, including dopamine beta-hydroxylase deficiency; inflammatory bowel disease; and rheumatoid arthritis. Is an ortholog of human HSPA5 (heat shock protein family A (Hsp70) member 5). WB:WBGene00002008 hsp-4 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in endoplasmic reticulum unfolded protein response. Located in rough endoplasmic reticulum. Expressed in PVDL; PVDR; intestinal muscle; and spermatheca. Human ortholog(s) of this gene implicated in several diseases, including dopamine beta-hydroxylase deficiency; inflammatory bowel disease; and rheumatoid arthritis. Is an ortholog of human HSPA5 (heat shock protein family A (Hsp70) member 5). WB:WBGene00002009 hsp-5 No description available WB:WBGene00002010 hsp-6 Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Involved in mitochondrial unfolded protein response. Located in mitochondrion. Expressed in muscle cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; autosomal dominant sideroblastic anemia 4; and rheumatoid arthritis. Is an ortholog of human HSPA9 (heat shock protein family A (Hsp70) member 9). WB:WBGene00002011 hsp-12.2 Enables heat shock protein binding activity. Predicted to be involved in protein refolding and response to heat. Located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease axonal type 2F; cataract (multiple); and myofibrillar myopathy (multiple). Is an ortholog of human CRYAA (crystallin alpha A); CRYAB (crystallin alpha B); and HSPB6 (heat shock protein family B (small) member 6). WB:WBGene00002012 hsp-12.3 Enables heat shock protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in cataract (multiple); dilated cardiomyopathy 1II; and myofibrillar myopathy (multiple). Is an ortholog of human CRYAA (crystallin alpha A); CRYAB (crystallin alpha B); and HSPB6 (heat shock protein family B (small) member 6). WB:WBGene00002013 hsp-12.6 Enables identical protein binding activity. Predicted to be involved in protein refolding and response to heat. Located in cytoplasm. Expressed in hypodermis; intestine; muscle cell; and spermatid. Human ortholog(s) of this gene implicated in cataract (multiple); dilated cardiomyopathy 1II; and myofibrillar myopathy (multiple). Is an ortholog of human CRYAA (crystallin alpha A); CRYAB (crystallin alpha B); and HSPB6 (heat shock protein family B (small) member 6). WB:WBGene00002015 hsp-16.1 Predicted to enable unfolded protein binding activity. Involved in defense response to Gram-negative bacterium and response to heat. Located in Golgi medial cisterna. Expressed in several structures, including coelomocyte; enteric muscle; intestine; pharynx; and ventral nerve cord. WB:WBGene00002016 hsp-16.2 Predicted to enable unfolded protein binding activity. Involved in response to heat. Located in cytoplasm. Expressed in several structures, including coelomocyte; enteric muscle; gonad; somatic nervous system; and spermatid. WB:WBGene00002017 hsp-16.11 Predicted to enable unfolded protein binding activity. Involved in endoplasmic reticulum unfolded protein response. WB:WBGene00002018 hsp-16.41 Predicted to enable unfolded protein binding activity. Involved in defense response to Gram-negative bacterium and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including alimentary muscle; coelomocyte; intestine; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Is an ortholog of human CRYAA (crystallin alpha A). WB:WBGene00002019 hsp-16.48 Predicted to enable unfolded protein binding activity. Involved in determination of adult lifespan and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including coelomocyte; enteric muscle; intestine; nervous system; and pharynx. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Is an ortholog of human CRYAA (crystallin alpha A). WB:WBGene00002020 hsp-16.49 Predicted to enable unfolded protein binding activity. Involved in endoplasmic reticulum unfolded protein response. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Is an ortholog of human CRYAA (crystallin alpha A). WB:WBGene00002021 hsp-17 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in excretory cell. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Is an ortholog of human CRYAA (crystallin alpha A). WB:WBGene00002023 hsp-25 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Located in M band and striated muscle dense body. Expressed in body wall musculature; gonad; pharynx; and spermatheca. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and distal hereditary motor neuronopathy type 2A. Is an ortholog of human HSPB8 (heat shock protein family B (small) member 8). WB:WBGene00002024 hsp-43 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including copulatory spicule; hermaphrodite gonad; pharyngeal-intestinal valve; rectal valve cell; and vulva. WB:WBGene00002025 hsp-60 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including mitochondrial unfolded protein response; mitochondrion organization; and nematode larval development. Located in mitochondrion. Expressed in hypodermis; intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; artery disease (multiple); and autoimmune disease of musculoskeletal system (multiple). Is an ortholog of human HSPD1 (heat shock protein family D (Hsp60) member 1). WB:WBGene00002026 hsp-70 Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Involved in determination of adult lifespan and response to heat. Part of chaperonin-containing T-complex. Is an ortholog of human HSPA6 (heat shock protein family A (Hsp70) member 6) and HSPA7 (heat shock protein family A (Hsp70) member 7 (pseudogene)). WB:WBGene00002027 hsr-9 Predicted to enable histone binding activity. Predicted to be involved in DNA damage checkpoint signaling and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in germ cell. Human ortholog(s) of this gene implicated in pulmonary hypertension. Is an ortholog of human TP53BP1 (tumor protein p53 binding protein 1). WB:WBGene00002028 hst-1 Predicted to enable [heparan sulfate]-glucosamine N-sulfotransferase activity and deacetylase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 46. Is an ortholog of several human genes including NDST1 (N-deacetylase and N-sulfotransferase 1); NDST2 (N-deacetylase and N-sulfotransferase 2); and NDST3 (N-deacetylase and N-sulfotransferase 3). WB:WBGene00002029 hst-2 Enables heparan sulfate 2-O-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification; regulation of growth; and regulation of locomotion. Predicted to be located in Golgi apparatus. Expressed in several structures, including P6.paa; P6.pap; P6.ppa; hermaphrodite distal tip cell; and somatic nervous system. Is an ortholog of human HS2ST1 (heparan sulfate 2-O-sulfotransferase 1). WB:WBGene00002030 hst-3.1 Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Expressed in several structures, including coelomocyte; distal tip cell; neurons; non-striated muscle; and rectal epithelial cell. Is an ortholog of human HS3ST1 (heparan sulfate-glucosamine 3-sulfotransferase 1) and HS3ST5 (heparan sulfate-glucosamine 3-sulfotransferase 5). WB:WBGene00002031 hst-6 Predicted to enable heparan sulfate 6-O-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification and regulation of growth. Predicted to be located in membrane. Expressed in AIBL; AIBR; RIML; RIMR; and neurons. Human ortholog(s) of this gene implicated in Paganini-Miozzo syndrome and hypogonadotropic hypogonadism 15 with or without anosmia. Is an ortholog of human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1). WB:WBGene00002032 htp-1 Involved in regulation of centriole-centriole cohesion. Located in lateral element. Expressed in Z2 and Z3. Is an ortholog of human HORMAD1 (HORMA domain containing 1). WB:WBGene00002033 htp-2 Involved in regulation of centriole-centriole cohesion. Located in lateral element. WB:WBGene00002034 htp-3 Involved in homologous chromosome pairing at meiosis and meiotic DNA double-strand break formation. Located in lateral element. Part of chromatin. Expressed in Z2; Z3; embryonic cell; germ line; and neurons. WB:WBGene00002035 hum-1 Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be located in several cellular components, including actin cytoskeleton; microvillus; and vesicle. Predicted to be part of myosin complex. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 6. Is an ortholog of human MYO1E (myosin IE). WB:WBGene00002036 hum-2 Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be located in actin cytoskeleton; cytoplasm; and vesicle. Predicted to be part of myosin complex. Expressed in DB1. Human ortholog(s) of this gene implicated in Griscelli syndrome type 1; microvillus inclusion disease; and progressive familial intrahepatic cholestasis. Is an ortholog of human MYO5A (myosin VA); MYO5B (myosin VB); and MYO5C (myosin VC). WB:WBGene00002037 hum-4 Enables calmodulin binding activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be located in several cellular components, including actin cytoskeleton; actin-based cell projection; and vesicle. Predicted to be part of myosin complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 3 and sensorineural hearing loss. Is an ortholog of human MYO15A (myosin XVA) and MYO16 (myosin XVI). WB:WBGene00002038 hum-5 Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be located in several cellular components, including actin cytoskeleton; microvillus; and vesicle. Predicted to be part of myosin complex. Expressed in head and tail. Is an ortholog of human MYO1G (myosin IG). WB:WBGene00002039 hum-6 Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament-based process; sensory organ development; and sensory perception of sound. Predicted to be located in several cellular components, including actin cytoskeleton; microvillus; and vesicle. Predicted to be part of myosin VI complex. Human ortholog(s) of this gene implicated in several diseases, including Usher syndrome type 1; auditory system disease (multiple); and congenital nystagmus. Is an ortholog of human MYO7A (myosin VIIA). WB:WBGene00002040 hum-7 Enables calmodulin binding activity and plus-end directed microfilament motor activity. Involved in actin-myosin filament sliding. Predicted to be located in actin filament. Predicted to be part of myosin complex. Expressed in accessory cell; pharynx; pm6; pm7; and terminal bulb. Human ortholog(s) of this gene implicated in celiac disease and congenital myasthenic syndrome. Is an ortholog of human MYO9A (myosin IXA). WB:WBGene00002041 hum-8 Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization; endocytosis; and vesicle transport along actin filament. Predicted to be located in actin cytoskeleton and endocytic vesicle. Predicted to be part of myosin complex. Human ortholog(s) of this gene implicated in auditory system disease (multiple) and reproductive organ cancer (multiple). Is an ortholog of human MYO6 (myosin VI). WB:WBGene00002042 hus-1 Involved in several processes, including DNA damage response; determination of adult lifespan; and telomere maintenance. Located in germ cell nucleus. Part of chromatin. Expressed in germ line. Is an ortholog of human HUS1B (HUS1 checkpoint clamp component B). WB:WBGene00002043 hyl-1 Predicted to enable sphingosine N-acyltransferase activity. Involved in regulation of locomotion. Located in axon. Expressed in motor neurons. Is an ortholog of human CERS6 (ceramide synthase 6). WB:WBGene00002044 hyl-2 Predicted to enable sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Expressed in head; hypodermis; intestine; tail; and terminal bulb. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 9. Is an ortholog of human CERS6 (ceramide synthase 6). WB:WBGene00002045 icd-1 Involved in embryo development and negative regulation of apoptotic process. Located in mitochondrion. Expressed in several structures, including germ line; intestine; pharynx; preanal ganglion; and somatic nervous system. Is an ortholog of human BTF3 (basic transcription factor 3) and BTF3L4 (basic transcription factor 3 like 4). WB:WBGene00002046 icln-1 Predicted to be involved in mRNA cis splicing, via spliceosome and spliceosomal snRNP assembly. Predicted to be located in cytosol. Predicted to be part of pICln-Sm protein complex and spliceosomal complex. Is an ortholog of human CLNS1A (chloride nucleotide-sensitive channel 1A). WB:WBGene00002047 icp-1 Enables protein serine/threonine kinase activator activity. Involved in mitotic cytokinesis and nuclear division. Located in kinetochore and nucleus. Is an ortholog of human INCENP (inner centromere protein). WB:WBGene00002048 ida-1 Predicted to enable transmembrane receptor protein tyrosine phosphatase activity. Involved in positive regulation of anterior/posterior axon guidance; positive regulation of neurotransmitter secretion; and ventral cord development. Located in dense core granule and synapse. Expressed in several structures, including buccal cavity; neurons; preanal ganglion; somatic nervous system; and uv1. Used to study Parkinson's disease and diabetes mellitus. Human ortholog(s) of this gene implicated in prediabetes syndrome and type 1 diabetes mellitus. Is an ortholog of human PTPRN2 (protein tyrosine phosphatase receptor type N2). WB:WBGene00002049 idf-1 Acts upstream of or within body morphogenesis and syncytium formation by plasma membrane fusion. WB:WBGene00002050 ifa-1 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Located in intermediate filament. Expressed in several structures, including egg-laying apparatus; excretory cell; neurons; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). WB:WBGene00002051 ifa-3 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Predicted to be located in nuclear envelope and nuclear lamina. Expressed in hypodermis and ventral cord neurons. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). WB:WBGene00002052 ifa-4 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Predicted to be located in intermediate filament; nuclear envelope; and nuclear lamina. Expressed in several structures, including egg-laying apparatus; excretory canal; pharyngeal-intestinal valve; rectum; and spermathecal-uterine valve cell. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). WB:WBGene00002053 ifb-1 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Located in apical plasma membrane. Expressed in several structures, including egg-laying apparatus; excretory system; pharyngeal-intestinal valve; pharynx; and somatic nervous system. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). WB:WBGene00002054 ifb-2 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Located in apical cortex; cell junction; and terminal web. Expressed in intestine. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). WB:WBGene00002055 ifc-1 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Predicted to be located in nuclear envelope and nuclear lamina. Expressed in hypodermis; intestine; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including Dowling-Degos disease; ichthyosis (multiple); and palmoplantar keratosis (multiple). Is an ortholog of several human genes including KRT1 (keratin 1); KRT2 (keratin 2); and KRT3 (keratin 3). WB:WBGene00002056 ifc-2 Predicted to be a structural constituent of cytoskeleton. Involved in post-embryonic digestive tract morphogenesis. Located in cytoplasm and desmosome. Expressed in several structures, including excretory canal; intestinal cell; pharyngeal-intestinal valve; pharynx; and rectal valve cell. Human ortholog(s) of this gene implicated in several diseases, including Dowling-Degos disease; ichthyosis (multiple); and palmoplantar keratosis (multiple). Is an ortholog of several human genes including KRT1 (keratin 1); KRT2 (keratin 2); and KRT3 (keratin 3). WB:WBGene00002057 ifd-1 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Predicted to be located in nuclear envelope and nuclear lamina. Expressed in intestine. WB:WBGene00002058 ifd-2 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Predicted to be located in nuclear envelope and nuclear lamina. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including DES (desmin); GFAP (glial fibrillary acidic protein); and KRT7 (keratin 7). WB:WBGene00002059 ife-1 Enables RNA 7-methylguanosine cap binding activity and RNA trimethylguanosine cap binding activity. Involved in embryo development; oocyte maturation; and spermatid development. Located in P granule. Expressed in germ line; gonad; oocyte; primary spermatocyte; and secondary spermatocyte. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human EIF4E (eukaryotic translation initiation factor 4E) and EIF4E1B (eukaryotic translation initiation factor 4E family member 1B). WB:WBGene00002060 ife-2 Enables RNA 7-methylguanosine cap binding activity and RNA trimethylguanosine cap binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of response to oxidative stress; and positive regulation of translation. Located in cytoplasmic stress granule. Expressed in several structures, including excretory canal; germ line; pharynx; spermatheca; and vulva. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human EIF4E (eukaryotic translation initiation factor 4E) and EIF4E1B (eukaryotic translation initiation factor 4E family member 1B). WB:WBGene00002061 ife-3 Enables RNA 7-methylguanosine cap binding activity. Involved in embryo development. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of eukaryotic translation initiation factor 4F complex. Expressed in germ line; gonad; and oocyte. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human EIF4E (eukaryotic translation initiation factor 4E) and EIF4E1B (eukaryotic translation initiation factor 4E family member 1B). WB:WBGene00002062 ife-4 Enables RNA 7-methylguanosine cap binding activity. Predicted to be involved in regulation of translation and translational initiation. Predicted to be part of eukaryotic translation initiation factor 4F complex. Expressed in several structures, including HSN; pharyngeal cell; somatic cell; somatic gonad precursor; and somatic nervous system. Is an ortholog of human EIF4E2 (eukaryotic translation initiation factor 4E family member 2). WB:WBGene00002063 ife-5 Enables RNA 7-methylguanosine cap binding activity and RNA trimethylguanosine cap binding activity. Involved in embryo development. Predicted to be part of eukaryotic translation initiation factor 4F complex. Expressed in germ line. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human EIF4E (eukaryotic translation initiation factor 4E). WB:WBGene00002064 iff-1 Predicted to enable translation elongation factor activity. Involved in gamete generation and protein localization. Predicted to be located in cytoplasm. Expressed in germ line and gonad. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human EIF5A (eukaryotic translation initiation factor 5A). WB:WBGene00002065 iff-2 Predicted to enable translation elongation factor activity. Involved in gamete generation; nematode larval development; and sex differentiation. Predicted to be located in cytoplasm. Expressed in excretory cell; hypodermis; pharynx; rectal muscle; and spermatheca. Is an ortholog of human EIF5A2 (eukaryotic translation initiation factor 5A2) and EIF5AL1 (eukaryotic translation initiation factor 5A like 1). WB:WBGene00002066 ifg-1 Predicted to enable mRNA binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Located in cytosol. Part of eukaryotic translation initiation factor 4F complex. Expressed in several structures, including gonad. Human ortholog(s) of this gene implicated in late onset Parkinson's disease. Is an ortholog of human EIF4G3 (eukaryotic translation initiation factor 4 gamma 3). WB:WBGene00002067 ifp-1 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Predicted to be located in nuclear envelope and nuclear lamina. Expressed in head; head neurons; intestine; pharynx; and ventral nerve cord. WB:WBGene00002068 ify-1 Enables protease binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including cortical granule exocytosis; nuclear division; and protein stabilization. Located in condensed chromosome; cytoplasm; and spindle microtubule. Expressed in germ cell. WB:WBGene00002069 ikb-1 Predicted to enable NF-kappaB binding activity. Involved in defense response to Gram-negative bacterium. Located in cytoplasm. Human ortholog(s) of this gene implicated in common variable immunodeficiency 10. Is an ortholog of human NFKB2 (nuclear factor kappa B subunit 2). WB:WBGene00002070 ile-1 Predicted to enable mannose binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in factor V deficiency and factor XIII deficiency. Is an ortholog of human LMAN1 (lectin, mannose binding 1). WB:WBGene00002071 ile-2 Predicted to enable mannose binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder and autosomal recessive intellectual developmental disorder 52. Is an ortholog of human LMAN2 (lectin, mannose binding 2) and LMAN2L (lectin, mannose binding 2 like). WB:WBGene00002072 ima-1 Enables nuclear import signal receptor activity. Involved in protein import into nucleus. Located in cytoplasm and nucleoplasm. Part of nuclear pore. Expressed in germ line. WB:WBGene00002073 ima-2 Enables nuclear import signal receptor activity. Involved in several processes, including organelle organization; protein import into nucleus; and regulation of chromosome segregation. Located in cytoplasm and nuclear envelope. Expressed in Z2; Z3; and germ line. Is an ortholog of human KPNA2 (karyopherin subunit alpha 2) and KPNA7 (karyopherin subunit alpha 7). WB:WBGene00002074 ima-3 Enables nuclear import signal receptor activity. Involved in several processes, including nuclear pore organization; protein import into nucleus; and sexual reproduction. Located in cytoplasm and nuclear envelope. Part of nuclear pore. Expressed in germ line; gonad; hypodermis; muscle cell; and neurons. Is an ortholog of human KPNA3 (karyopherin subunit alpha 3) and KPNA4 (karyopherin subunit alpha 4). WB:WBGene00002075 imb-1 Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Involved in embryo development and reproduction. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human KPNB1 (karyopherin subunit beta 1). WB:WBGene00002076 imb-2 Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in protein import into nucleus. Predicted to be located in cytoplasm and nucleus. Expressed in AWC-ON; AWCL; and AWCR. Human ortholog(s) of this gene implicated in intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies. Is an ortholog of human TNPO2 (transportin 2). WB:WBGene00002077 imb-3 Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in protein import into nucleus. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human IPO5 (importin 5) and RANBP6 (RAN binding protein 6). WB:WBGene00002078 xpo-1 Predicted to enable nuclear export signal receptor activity. Predicted to be involved in ribosomal large subunit export from nucleus and ribosomal small subunit export from nucleus. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung adenocarcinoma; and pancreatic cancer. Is an ortholog of human XPO1 (exportin 1). WB:WBGene00002079 xpo-2 Predicted to enable nuclear export signal receptor activity. Predicted to be involved in protein export from nucleus and protein import into nucleus. Predicted to be located in cytosol and nuclear envelope. Is an ortholog of human CSE1L (chromosome segregation 1 like). WB:WBGene00002080 xpo-3 Predicted to enable tRNA binding activity. Predicted to be involved in tRNA re-export from nucleus. Predicted to be located in cytoplasm and nuclear matrix. Predicted to be part of nuclear pore. Is an ortholog of human XPOT (exportin for tRNA). WB:WBGene00002081 ina-1 Enables transmembrane signaling receptor activity. Involved in several processes, including anatomical structure morphogenesis; cell-cell adhesion mediated by integrin; and generation of neurons. Located in phagocytic cup. Part of integrin complex. Expressed in several structures, including distal tip cell; hermaphrodite gonad; neurons; ventral nerve cord; and vulE. Used to study cancer and epilepsy. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; congenital muscular dystrophy due to integrin alpha-7 deficiency; and junctional epidermolysis bullosa with pyloric atresia. Is an ortholog of human ITGA6 (integrin subunit alpha 6). WB:WBGene00002082 inb-1 No description available WB:WBGene00002083 inf-1 Predicted to enable translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to be located in cytoplasmic stress granule. Expressed in germ line; intestine; and neurons. Is an ortholog of human EIF4A1 (eukaryotic translation initiation factor 4A1). WB:WBGene00002084 ins-1 Predicted to enable hormone activity. Involved in several processes, including learning or memory; negative regulation of insulin receptor signaling pathway; and regulation of dauer entry. Located in several cellular components, including cytoplasmic vesicle; neuron projection; and neuronal cell body. Expressed in several structures, including distal tip cell; egg-laying apparatus; head muscle; neurons; and somatic nervous system. WB:WBGene00002085 ins-2 Predicted to enable hormone activity. Involved in negative regulation of dauer entry. Predicted to be located in extracellular region. Expressed in amphid sensillum; ciliated neurons; head muscle; intestine; and nerve ring. WB:WBGene00002086 ins-3 Predicted to enable hormone activity. Involved in dauer larval development and negative regulation of dauer entry. Predicted to be located in extracellular region. Expressed in several structures, including coelomocyte; egg-laying apparatus; gonad; head muscle; and nervous system. WB:WBGene00002087 ins-4 Predicted to enable hormone activity. Involved in dauer larval development; negative regulation of dauer entry; and regulation of synaptic assembly at neuromuscular junction. Predicted to be located in extracellular region. Expressed in several structures, including gonad; head muscle; neurons; somatic nervous system; and vulva. WB:WBGene00002088 ins-5 Predicted to enable hormone activity. Involved in dauer larval development. Predicted to be located in extracellular region. Expressed in several structures, including coelomocyte; head muscle; neurons; somatic nervous system; and vulva. WB:WBGene00002089 ins-6 Enables insulin receptor binding activity. Involved in several processes, including insulin receptor signaling pathway; negative regulation of dauer entry; and olfactory learning. Predicted to be located in extracellular space. Expressed in several structures, including ciliated neurons; coelomocyte; head muscle; somatic nervous system; and tail. WB:WBGene00002090 ins-7 Predicted to enable hormone activity. Involved in olfactory learning. Predicted to be located in extracellular region and membrane. Expressed in several structures, including distal tip cell; egg-laying apparatus; head muscle; neurons; and somatic nervous system. WB:WBGene00002091 ins-8 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in several structures, including egg-laying apparatus; gonad; head muscle; neurons; and somatic nervous system. WB:WBGene00002092 ins-9 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in coelomocyte; intestine; nerve ring; and neurons. WB:WBGene00002093 ins-10 Expressed in several structures, including coelomocyte; head muscle; neurons; ventral nerve cord; and vulva. WB:WBGene00002094 ins-11 Involved in innate immune response. Predicted to be located in extracellular region. Expressed in several structures, including coelomocyte; distal tip cell; head muscle; neurons; and somatic nervous system. WB:WBGene00002095 ins-12 Expressed in head neurons; motor neurons; nerve ring neurons; rectum; and sensory neurons. Is predicted to encode a protein with the following domain: Insulin-like superfamily. WB:WBGene00002096 ins-13 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in intestine; neurons; and rectum. WB:WBGene00002097 ins-14 Expressed in head neurons; motor neurons; nerve ring neurons; and sensory neurons. Is predicted to encode a protein with the following domain: Insulin-like superfamily. WB:WBGene00002098 ins-15 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in several structures, including egg-laying apparatus; gonad; head muscle; neurons; and ventral nerve cord. WB:WBGene00002099 ins-16 Expressed in distal tip cell; intestine; neurons; and pharynx. Is predicted to encode a protein with the following domain: Insulin-like superfamily. WB:WBGene00002100 ins-17 Involved in dauer larval development. Predicted to be located in extracellular region. Expressed in several structures, including egg-laying apparatus; gonad; head muscle; neurons; and somatic nervous system. WB:WBGene00002101 ins-18 Involved in maintenance of dauer; negative regulation of insulin receptor signaling pathway; and regulation of dauer entry. Expressed in several structures, including coelomocyte; gonad; head muscle; nerve ring; and neurons. WB:WBGene00002102 ins-19 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. WB:WBGene00002103 ins-20 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in head neurons and sensory neurons. WB:WBGene00002104 ins-21 Predicted to be located in extracellular region. Expressed in intestine; nerve ring; neurons; spermatheca; and vulval muscle. WB:WBGene00002105 ins-22 Predicted to be located in extracellular region. Expressed in nervous system; pharynx; rectum; and vulval muscle. WB:WBGene00002106 ins-23 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in gonad; neurons; non-striated muscle; pharynx; and somatic nervous system. WB:WBGene00002107 ins-24 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. WB:WBGene00002108 ins-25 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in motor neurons; nerve ring neurons; and tail neurons. WB:WBGene00002109 ins-26 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in several structures, including coelomocyte; head muscle; intestine; neurons; and ventral nerve cord. WB:WBGene00002110 ins-27 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in body wall musculature; distal tip cell; hypodermis; neurons; and non-striated muscle. WB:WBGene00002111 ins-28 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in coelomocyte; intestine; neurons; and vulva. WB:WBGene00002112 ins-29 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in coelomocyte; head neurons; pharynx; and sensory neurons. WB:WBGene00002113 ins-30 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in head muscle; intestine; neurons; and ventral nerve cord. WB:WBGene00002114 ins-31 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in coelomocyte; male gonad; and seminal vesicle. WB:WBGene00002115 ins-32 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in intestine and nervous system. WB:WBGene00002116 ins-33 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in head muscle; head neurons; and tail. WB:WBGene00002117 ins-34 Expressed in several structures, including coelomocyte; head muscle; intestine; uterus; and ventral nerve cord. WB:WBGene00002118 ins-35 Predicted to enable insulin receptor binding activity. Involved in insulin receptor signaling pathway and negative regulation of dauer larval development. Located in extracellular space. Expressed in neurons; rectum; and ventral nerve cord. WB:WBGene00002119 ins-36 Expressed in several structures, including coelomocyte; head muscle; intestine; neurons; and ventral nerve cord. WB:WBGene00002120 ins-37 Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in intestine. WB:WBGene00002121 ins-38 Expressed in coelomocyte; neurons; and ventral nerve cord. WB:WBGene00002123 inx-1 Predicted to enable gap junction channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Located in gap junction. Expressed in neurons and pm1. WB:WBGene00002124 inx-2 Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in gap junction and plasma membrane. Expressed in AVK; intestine; pharyngeal-intestinal valve; and pharynx. WB:WBGene00002125 inx-3 Enables actin filament binding activity and gap junction channel activity. Involved in embryonic morphogenesis and positive regulation of pharyngeal pumping. Located in cytoplasm and gap junction. Expressed in several structures, including arcade cell; cephalic sheath cell; neurons; pharyngeal cell; and rectum. WB:WBGene00002127 inx-5 Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in gap junction and plasma membrane. Expressed in hermaphrodite gonad; interfacial epithelial cell; interneuron; and intestine. WB:WBGene00002128 inx-6 Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in gap junction and plasma membrane. Expressed in head neurons; pharyngeal cell; and rectal valve cell. WB:WBGene00002129 inx-7 Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in gap junction and plasma membrane. Expressed in neurons; pharyngeal cell; and rectal gland cell. WB:WBGene00002130 inx-8 Predicted to enable gap junction hemi-channel activity. Acts upstream of or within with a positive effect on germ cell proliferation. Located in gap junction. Expressed in several structures, including egg-laying apparatus; ganglia; gonad; pharyngeal muscle cell; and spermatocyte. WB:WBGene00002131 inx-9 Predicted to enable gap junction channel activity. Acts upstream of or within with a positive effect on germ cell proliferation. Located in gap junction. Expressed in several structures, including gonad; interfacial epithelial cell; nerve ring neurons; pharyngeal cell; and spermatocyte. WB:WBGene00002132 inx-10 Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Located in gap junction. Expressed in several structures, including DD neuron; hermaphrodite gonad; interneuron; pharyngeal cell; and rectal epithelium. WB:WBGene00002133 inx-11 Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Located in gap junction. Expressed in several structures, including egg-laying apparatus; epithelial cell; pharynx; spermatocyte; and tail neurons. WB:WBGene00002134 inx-12 Predicted to enable gap junction hemi-channel activity. Involved in positive regulation of nematode male tail tip morphogenesis. Predicted to be located in gap junction and plasma membrane. Expressed in several structures, including head ganglion; interfacial epithelial cell; neurons; posterior lateral ganglion; and tail hypodermis. WB:WBGene00002135 inx-13 Predicted to enable gap junction channel activity. Involved in positive regulation of nematode male tail tip morphogenesis. Predicted to be located in gap junction and plasma membrane. Expressed in several structures, including CAN; amphid sheath cell; ganglia; pharyngeal motor neurons; and tail hypodermis. WB:WBGene00002136 inx-14 Predicted to enable gap junction hemi-channel activity. Acts upstream of or within with a positive effect on germ cell proliferation. Acts upstream of or within with a negative effect on oocyte maturation. Located in gap junction. Expressed in several structures, including GABAergic neurons; germ cell; germ line; non-striated muscle; and somatic gonad precursor. WB:WBGene00002137 inx-15 Predicted to enable gap junction channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in gap junction and plasma membrane. Expressed in intestine. WB:WBGene00002138 inx-16 Predicted to enable gap junction hemi-channel activity. Involved in calcium-mediated signaling; regulation of defecation rhythm; and regulation of neuromuscular synaptic transmission. Located in gap junction. Expressed in intestine. WB:WBGene00002139 inx-17 Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in gap junction and plasma membrane. Expressed in nerve ring neurons and rectal valve cell. WB:WBGene00002140 inx-18 Predicted to enable gap junction channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Located in gap junction. Expressed in g1; head neurons; and interneuron. WB:WBGene00002141 inx-19 Enables calcium channel inhibitor activity; gap junction hemi-channel activity; and protein kinase inhibitor activity. Involved in determination of left/right asymmetry in nervous system and intercellular transport. Located in gap junction and neuronal cell body membrane. Expressed in several structures, including K' cell; head neurons; hermaphrodite distal tip cell; lumbar neurons; and pharyngeal neurons. WB:WBGene00002142 inx-20 Predicted to enable gap junction channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in gap junction and plasma membrane. Expressed in pharyngeal cell and rectal valve cell. WB:WBGene00002143 inx-21 Predicted to enable gap junction channel activity. Acts upstream of or within with a positive effect on germ cell proliferation. Located in gap junction. Expressed in several structures, including Z2; Z3; germ cell; intestine; and somatic gonad precursor. WB:WBGene00002144 inx-22 Predicted to enable gap junction channel activity. Acts upstream of or within with a positive effect on germ cell proliferation. Acts upstream of or within with a negative effect on oocyte maturation. Located in gap junction. Expressed in several structures, including GLR; germ cell; germ line; gonad; and somatic gonad precursor. WB:WBGene00002145 ipp-2 No description available WB:WBGene00002146 ipp-5 Predicted to enable inositol-polyphosphate 5-phosphatase activity. Involved in epidermal growth factor receptor signaling pathway; inositol phosphate-mediated signaling; and ovulation. Expressed in spermatheca. Is an ortholog of human INPP5A (inositol polyphosphate-5-phosphatase A). WB:WBGene00002147 ire-1 Enables RNA endonuclease activity. Involved in nematode larval development; positive regulation of transcription by RNA polymerase II; and response to hypoxia. Acts upstream of with a positive effect on IRE1-mediated unfolded protein response and intrinsic apoptotic signaling pathway by p53 class mediator. Located in neuronal cell body. Expressed widely. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and oropharynx cancer. Is an ortholog of human ERN2 (endoplasmic reticulum to nucleus signaling 2). WB:WBGene00002148 gon-14 Enables signaling receptor binding activity. Involved in several processes, including gonad morphogenesis; negative regulation of vulval development; and system process. Located in nucleus. Expressed in several structures, including amphid socket cell; anal sphincter muscle; gonad; pharyngeal segment; and somatic gonad precursor. WB:WBGene00002149 irk-1 Enables inward rectifier potassium channel activity. Involved in regulation of G protein-coupled receptor signaling pathway and regulation of egg-laying behavior. Located in neuron projection and neuronal cell body. Expressed in egg-laying apparatus; gonad; intestine; and neurons. Human ortholog(s) of this gene implicated in several diseases, including glucose metabolism disease (multiple); heart conduction disease (multiple); and long QT syndrome (multiple). Is an ortholog of several human genes including KCNJ2 (potassium inwardly rectifying channel subfamily J member 2); KCNJ3 (potassium inwardly rectifying channel subfamily J member 3); and KCNJ4 (potassium inwardly rectifying channel subfamily J member 4). WB:WBGene00002150 irk-2 Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of monoatomic ion transmembrane transport. Predicted to be located in plasma membrane. Expressed in intestine; pharyngeal-intestinal valve cell; spermatheca; and uterus. Human ortholog(s) of this gene implicated in several diseases, including glucose metabolism disease (multiple); heart conduction disease (multiple); and long QT syndrome (multiple). Is an ortholog of several human genes including KCNJ2 (potassium inwardly rectifying channel subfamily J member 2); KCNJ4 (potassium inwardly rectifying channel subfamily J member 4); and KCNJ5 (potassium inwardly rectifying channel subfamily J member 5). WB:WBGene00002151 irk-3 Predicted to enable inward rectifier potassium channel activity. Involved in short-term memory. Predicted to be located in plasma membrane. Expressed in HSNL; HSNR; and sensory neurons. Human ortholog(s) of this gene implicated in several diseases, including Bartter disease type 2; EAST syndrome; and Leber congenital amaurosis 16. Is an ortholog of human KCNJ10 (potassium inwardly rectifying channel subfamily J member 10); KCNJ13 (potassium inwardly rectifying channel subfamily J member 13); and KCNJ15 (potassium inwardly rectifying channel subfamily J member 15). WB:WBGene00002152 iars-1 Predicted to enable isoleucine-tRNA ligase activity. Predicted to be involved in isoleucyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Expressed in body wall musculature; hypodermis; and ventral nerve cord. Is an ortholog of human IARS1 (isoleucyl-tRNA synthetase 1). WB:WBGene00002153 iars-2 Predicted to enable isoleucine-tRNA ligase activity. Predicted to be involved in isoleucyl-tRNA aminoacylation and mitochondrial translation. Predicted to be located in mitochondrion. Is an ortholog of human IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial). WB:WBGene00002162 isp-1 Predicted to enable oxidoreductase activity. Involved in mitochondrial electron transport, ubiquinol to cytochrome c; positive regulation of nematode larval development; and regulation of macromolecule metabolic process. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex III. Expressed in head and tail. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency. Is an ortholog of human UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1) and UQCRFS1P1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 pseudogene 1). WB:WBGene00002163 ist-1 Predicted to enable insulin receptor binding activity; phosphatidylinositol 3-kinase binding activity; and transmembrane receptor protein tyrosine kinase adaptor activity. Involved in dauer larval development; insulin receptor signaling pathway; and short-term memory. WB:WBGene00002169 isw-1 Predicted to enable ATP-dependent activity, acting on DNA and DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and positive regulation of vulval development. Part of chromatin. Expressed in several structures, including head. Is an ortholog of human SMARCA1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1). WB:WBGene00002173 itr-1 Enables myosin binding activity. Involved in several processes, including multicellular organism reproduction; positive regulation of pharyngeal pumping; and system process. Located in endoplasmic reticulum and membrane. Expressed in several structures, including egg-laying apparatus; ganglia; gonad; non-striated muscle; and tail hypodermis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Gillespie syndrome; and isolated anhidrosis with normal sweat glands. Is an ortholog of human ITPR1 (inositol 1,4,5-trisphosphate receptor type 1); ITPR2 (inositol 1,4,5-trisphosphate receptor type 2); and ITPR3 (inositol 1,4,5-trisphosphate receptor type 3). WB:WBGene00002174 itx-1 Located in adherens junction and basolateral plasma membrane. Expressed in anterior ganglion; intestine; spermatheca; and vulval muscle. WB:WBGene00002175 jac-1 Enables cadherin binding activity. Involved in embryonic body morphogenesis; regulation of actin cytoskeleton organization; and regulation of protein localization. Located in adherens junction. Part of catenin complex. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including DiGeorge syndrome; blepharocheilodontic syndrome 2; and oral squamous cell carcinoma. Is an ortholog of human ARVCF (ARVCF delta catenin family member). WB:WBGene00002176 jip-1 Enriched in head mesodermal cell; neurons; pharynx; retrovesicular ganglion; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; sek-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; allantoin; and metformin based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Human MAPK8IP1 enables MAP-kinase scaffold activity and kinesin binding activity. Is predicted to encode a protein with the following domains: Variant SH3 domain; PH-like domain superfamily; PTB/PI domain; SH3-like domain superfamily; Phosphotyrosine interaction domain (PTB/PID); and SH3 domain. Is an ortholog of human MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1). WB:WBGene00002177 jkk-1 Enables JUN kinase kinase activity. Involved in hyperosmotic response and locomotion. Located in axon; cytoplasm; and neuronal cell body. Expressed in neurons. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lung adenocarcinoma; and prostate carcinoma in situ. Is an ortholog of human MAP2K7 (mitogen-activated protein kinase kinase 7). WB:WBGene00002178 jnk-1 Enables JUN kinase activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of cellular response to manganese ion; and vesicle transport along actin filament. Located in several cellular components, including axon; neuronal cell body; and nucleus. Expressed in AIYL; AIYR; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; abdominal aortic aneurysm; carcinoma (multiple); and intestinal benign neoplasm (multiple). Is an ortholog of human MAPK10 (mitogen-activated protein kinase 10); MAPK8 (mitogen-activated protein kinase 8); and MAPK9 (mitogen-activated protein kinase 9). WB:WBGene00002179 jph-1 Predicted to enable structural molecule activity. Involved in locomotion and positive regulation of engulfment of apoptotic cell. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Predicted to be part of junctional membrane complex. Expressed in body wall musculature; muscle cell; and nerve ring. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2K; Huntington's disease-like 2; and intrinsic cardiomyopathy (multiple). Is an ortholog of human JPH3 (junctophilin 3). WB:WBGene00002180 jtr-1 Predicted to be involved in mitotic cytokinesis. Predicted to be located in cytoplasm; microtubule cytoskeleton; and midbody. Is an ortholog of human JTB (jumping translocation breakpoint). WB:WBGene00002181 kal-1 Enables heparan sulfate proteoglycan binding activity; heparin binding activity; and syndecan binding activity. Involved in anatomical structure morphogenesis; embryo development; and neuron migration. Located in cell surface. Expressed in several structures, including egg-laying apparatus; excretory cell; nerve ring; neuroblasts; and neurons. Used to study Kallmann syndrome. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 1 with or without anosmia. Is an ortholog of human ANOS1 (anosmin 1). WB:WBGene00002182 kap-1 Contributes to microtubule motor activity. Involved in intraciliary anterograde transport; negative regulation of non-motile cilium assembly; and positive regulation of non-motile cilium assembly. Located in ciliary transition zone and non-motile cilium. Part of axonemal heterotrimeric kinesin-II complex. Expressed in ciliated neurons. Is an ortholog of human KIFAP3 (kinesin associated protein 3). WB:WBGene00002183 kat-1 Predicted to enable acetyl-CoA C-acetyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Located in mitochondrion. Expressed in body wall musculature. Used to study obesity. Human ortholog(s) of this gene implicated in arteriosclerosis; beta-ketothiolase deficiency; and carbohydrate metabolic disorder. Is an ortholog of human ACAT1 (acetyl-CoA acetyltransferase 1). WB:WBGene00002184 kel-1 Expressed in g1. Human ortholog(s) of this gene implicated in pseudohypoaldosteronism. Human KLHL3 enables cullin family protein binding activity and ubiquitin ligase-substrate adaptor activity. Is predicted to encode a protein with the following domains: Kelch-type beta propeller; Kelch repeat type 1; and Kelch motif. Is an ortholog of human KLHL3 (kelch like family member 3). WB:WBGene00002185 kel-3 Expressed in head and tail. Is predicted to encode a protein with the following domains: BTB/POZ domain; BTB-kelch protein; BTB And C-terminal Kelch; Kelch-type beta propeller; Kelch motif; BTB/Kelch-associated; SKP1/BTB/POZ domain superfamily; and Kelch repeat type 1. Is an ortholog of human KLHL18 (kelch like family member 18). WB:WBGene00002186 kel-10 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; methylmercury hydroxide; and nicotinic acid based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in spermatogenic failure 11. Is predicted to encode a protein with the following domains: BTB/POZ domain; BTB-kelch protein; BTB And C-terminal Kelch; Kelch-type beta propeller; Kelch motif; BTB/Kelch-associated; SKP1/BTB/POZ domain superfamily; and Kelch repeat type 1. Is an ortholog of human KLHL10 (kelch like family member 10). WB:WBGene00002187 kgb-1 Enables DEAD/H-box RNA helicase binding activity; JUN kinase activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including gamete generation; response to inorganic substance; and response to toxic substance. Located in cytoplasm. Expressed in several structures, including excretory cell; germ line; gonad; nerve ring; and tail ganglion. WB:WBGene00002188 kgb-2 Predicted to enable JUN kinase activity. Predicted to be involved in JNK cascade. Predicted to be located in cytoplasm and nucleus. WB:WBGene00002189 kin-1 Enables cAMP-dependent protein kinase activity. Involved in positive regulation of oocyte maturation. Predicted to be located in cytosol and nucleus. Predicted to be part of cAMP-dependent protein kinase complex. Expressed in several structures, including excretory cell; gonad; head muscle; intestine; and ventral cord neurons. Human ortholog(s) of this gene implicated in several diseases, including adrenal cortical adenoma; platelet-type bleeding disorder 19; and primary pigmented nodular adrenocortical disease. Is an ortholog of human PRKACA (protein kinase cAMP-activated catalytic subunit alpha). WB:WBGene00002190 kin-2 Predicted to enable cAMP-dependent protein kinase regulator activity. Involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling. Located in cytosol and membrane. Part of cAMP-dependent protein kinase complex. Expressed in body wall musculature; hypodermis; and intestine. Human ortholog(s) of this gene implicated in Carney complex; acrodysostosis; and primary pigmented nodular adrenocortical disease. Is an ortholog of human PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta). WB:WBGene00002191 kin-3 Enables protein serine/threonine kinase activity. Involved in response to hermaphrodite contact and vulval location. Located in neuronal cell body; nucleus; and plasma membrane bounded cell projection. Part of protein kinase CK2 complex. Expressed in oocyte. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human CSNK2A1 (casein kinase 2 alpha 1) and CSNK2A3 (casein kinase 2 alpha 3). WB:WBGene00002192 kin-4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm. Expressed in head neurons; intestine; and tail neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 108; female breast cancer; and mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations. Is an ortholog of human MAST1 (microtubule associated serine/threonine kinase 1) and MAST3 (microtubule associated serine/threonine kinase 3). WB:WBGene00002193 kin-5 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00002194 kin-6 Is affected by several genes including daf-12; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Tunicamycin; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00002195 kin-9 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. WB:WBGene00002196 kin-10 Predicted to enable protein kinase regulator activity. Involved in response to hermaphrodite contact and vulval location. Located in neuronal cell body; nucleus; and plasma membrane bounded cell projection. Part of protein kinase CK2 complex. Expressed in germ cell; gonad; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in leiomyoma. Is an ortholog of human CSNK2B (casein kinase 2 beta). WB:WBGene00002197 kin-12 No description available WB:WBGene00002198 kin-14 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Expressed in head neurons; marginal cell; pharyngeal muscle cell; pharyngeal-intestinal valve; and tail neurons. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00002199 kin-15 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in hyp6 and hyp7 syncytium. WB:WBGene00002200 kin-16 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in hyp6 and hyp7 syncytium. WB:WBGene00002201 kin-18 Predicted to enable protein serine/threonine kinase activity. Involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. Located in cell cortex. Expressed in several structures, including alimentary muscle; excretory cell; intestine; nerve ring; and pharyngeal-intestinal valve. Is an ortholog of human TAOK1 (TAO kinase 1); TAOK2 (TAO kinase 2); and TAOK3 (TAO kinase 3). WB:WBGene00002202 kin-19 Predicted to enable protein serine/threonine kinase activity. Involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in centrosome; cytoplasm; and nucleus. Expressed in several structures, including BDU; marginal cell; seam cell; tail; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease and inclusion body myositis. Is an ortholog of human CSNK1A1 (casein kinase 1 alpha 1). WB:WBGene00002203 kin-20 Enables protein serine/threonine kinase activity. Involved in regulation of collateral sprouting and regulation of locomotion. Located in adherens junction and nucleus. Expressed in several structures, including hypodermal cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; advanced sleep phase syndrome 2; and invasive ductal carcinoma. Is an ortholog of human CSNK1E (casein kinase 1 epsilon) and TPTEP2-CSNK1E (TPTEP2-CSNK1E readthrough). WB:WBGene00002204 kin-21 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00002205 kin-23 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00002206 kin-24 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00002207 sid-3 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in cytoplasm. Expressed in several structures, including excretory canal; intestine; phasmid neurons; rectal gland cell; and somatic cell. Is an ortholog of human TNK2 (tyrosine kinase non receptor 2). WB:WBGene00002208 kin-26 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00002209 kin-27 No description available WB:WBGene00002210 kin-29 Enables histone deacetylase inhibitor activity and protein serine/threonine kinase activity. Involved in several processes, including dauer entry; positive regulation of growth rate; and transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. Expressed in body wall musculature; hypodermis; intestine; nervous system; and non-striated muscle. WB:WBGene00002211 kin-30 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of several human genes including FLT3 (fms related receptor tyrosine kinase 3); KIT (KIT proto-oncogene, receptor tyrosine kinase); and PDGFRA (platelet derived growth factor receptor alpha). WB:WBGene00002212 kin-31 Expressed in body wall musculature. WB:WBGene00002213 kin-32 Predicted to enable ATP binding activity and protein tyrosine kinase activity. Predicted to be involved in regulation of cellular component organization and signal complex assembly. Predicted to be located in dendritic spine and focal adhesion. Expressed in body wall musculature; head mesodermal cell; head neurons; and uterine muscle. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ductal carcinoma in situ; and endometrial hyperplasia. Is an ortholog of human PTK2 (protein tyrosine kinase 2). WB:WBGene00002214 klc-1 Predicted to enable kinesin binding activity. Involved in establishment of meiotic spindle localization and polar body extrusion after meiotic divisions. Predicted to be located in cytoplasm. Predicted to be part of kinesin complex. Human ortholog(s) of this gene implicated in Alzheimer's disease and relapsing-remitting multiple sclerosis. Is an ortholog of human KLC1 (kinesin light chain 1). WB:WBGene00002215 klc-2 Enables kinesin binding activity. Involved in several processes, including axon extension; establishment of organelle localization; and polar body extrusion after meiotic divisions. Located in cytoplasm and nuclear envelope. Part of kinesin I complex. Expressed in body ganglion; muscle cell; pharynx; and somatic nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; SPOAN syndrome; and relapsing-remitting multiple sclerosis. Is an ortholog of human KLC1 (kinesin light chain 1) and KLC2 (kinesin light chain 2). WB:WBGene00002216 klp-3 Predicted to enable microtubule binding activity. Involved in chromosome separation. Predicted to be located in microtubule cytoskeleton. Expressed in marginal cell. Is an ortholog of human KIFC3 (kinesin family member C3). WB:WBGene00002217 klp-4 Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in cytoskeleton-dependent intracellular transport and microtubule-based movement. Located in axon; cytoplasmic microtubule; and neuronal cell body. Expressed in distal tip cell; dorsal nerve cord; head; and ventral nerve cord. Is an ortholog of human KIF13A (kinesin family member 13A) and KIF13B (kinesin family member 13B). WB:WBGene00002218 klp-6 Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in cytoskeleton-dependent intracellular transport and microtubule-based movement. Located in neuronal cell body and plasma membrane bounded cell projection. Expressed in ciliated neurons; head; tail; and in male. Used to study autosomal dominant polycystic kidney disease. Is an ortholog of human KIF28P (kinesin family member 28, pseudogene). WB:WBGene00002219 klp-7 Enables kinetochore binding activity. Involved in several processes, including egg-laying behavior; microtubule cytoskeleton organization; and regulation of cell cycle. Located in centrosome; kinetochore; and meiotic spindle pole. Expressed in distal tip cell; neurons; seam cell; and tail. Human ortholog(s) of this gene implicated in colorectal cancer and complex cortical dysplasia with other brain malformations 3. Is an ortholog of human KIF2A (kinesin family member 2A); KIF2B (kinesin family member 2B); and KIF2C (kinesin family member 2C). WB:WBGene00002220 gcc-1 Predicted to be located in Golgi apparatus. Expressed in several structures, including head. WB:WBGene00002221 klp-10 Enriched in germ line; head mesodermal cell; and intestine based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including daf-16; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00002222 klp-11 Enables microtubule motor activity. Involved in microtubule-based movement. Part of axonemal heterotrimeric kinesin-II complex. Expressed in amphid neurons; dorsal nerve cord; inner labial neurons; phasmid neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in retinitis pigmentosa 89. Is an ortholog of human KIF3B (kinesin family member 3B) and KIF3C (kinesin family member 3C). WB:WBGene00002223 klp-12 Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Predicted to be located in microtubule. Predicted to be part of kinesin complex. Expressed in head. Human ortholog(s) of this gene implicated in congenital fibrosis of the extraocular muscles 1. Is an ortholog of human KIF21B (kinesin family member 21B). WB:WBGene00002224 klp-13 Predicted to enable ATP hydrolysis activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Predicted to be involved in microtubule-based movement. Predicted to be located in microtubule. Predicted to be part of kinesin complex. Is an ortholog of human KIF19 (kinesin family member 19). WB:WBGene00002225 klp-15 Enables minus-end-directed microtubule motor activity. Involved in chromosome segregation and microtubule-based movement. Predicted to be located in microtubule cytoskeleton and nucleus. Predicted to be part of kinesin complex. Expressed in germ line and hypodermis. Is an ortholog of human KIFC1 (kinesin family member C1). WB:WBGene00002226 klp-16 Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in chromosome segregation. Located in neuronal cell body. Expressed in several structures, including ABa; EMS; Psub2; germ line; and head. WB:WBGene00002227 klp-17 Predicted to enable microtubule binding activity. Involved in chromosome segregation. Predicted to be located in microtubule cytoskeleton. Expressed in germ line and sperm. WB:WBGene00002228 klp-18 Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in meiotic spindle assembly. Located in cell cortex; microtubule; and spindle pole. Expressed in Z2; Z3; and germ line. Is an ortholog of human KIF15 (kinesin family member 15). WB:WBGene00002229 klp-19 Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in meiotic chromosome condensation and meiotic spindle midzone assembly. Located in condensed nuclear chromosome; nucleoplasm; and spindle. Expressed in germ line. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 100. Is an ortholog of human KIF4A (kinesin family member 4A). WB:WBGene00002230 klp-20 Enables microtubule motor activity. Involved in microtubule-based movement. Part of axonemal heterotrimeric kinesin-II complex. Expressed in ciliated neurons; distal tip cell; and head. Human ortholog(s) of this gene implicated in silicosis. Is an ortholog of human KIF3A (kinesin family member 3A). WB:WBGene00002231 knl-1 Enables microtubule binding activity. Involved in several processes, including mitotic spindle assembly checkpoint signaling; organelle organization; and positive regulation of protein localization to kinetochore. Located in kinetochore. Part of chromatin and outer kinetochore. WB:WBGene00002232 kpc-1 Enables serine-type endopeptidase activity and signaling receptor binding activity. Involved in several processes, including neuron development; positive regulation of developmental process; and protein processing. Located in neuronal cell body. Expressed in several structures, including PVD; epithelial cell; nervous system; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in arteriosclerosis; colon adenocarcinoma; and colorectal adenocarcinoma. Is an ortholog of human FURIN (furin, paired basic amino acid cleaving enzyme). WB:WBGene00002233 kqt-1 Enables potassium channel activity. Involved in G protein-coupled acetylcholine receptor signaling pathway; intracellular signal transduction; and potassium ion transport. Predicted to be located in plasma membrane and synapse. Predicted to be part of voltage-gated potassium channel complex. Expressed in head neurons; pharyngeal muscle cell; and touch receptor neurons. Used to study developmental and epileptic encephalopathy and long QT syndrome. Human ortholog(s) of this gene implicated in several diseases, including auditory system disease (multiple); autistic disorder; and electroclinical syndrome (multiple). Is an ortholog of human KCNQ4 (potassium voltage-gated channel subfamily Q member 4). WB:WBGene00002234 kqt-2 Predicted to enable calmodulin binding activity and outward rectifier potassium channel activity. Involved in defecation. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Expressed in amphid neurons; intestine; sensory neurons; tail; and in male. WB:WBGene00002235 kqt-3 Enables potassium channel activity. Involved in G protein-coupled acetylcholine receptor signaling pathway and potassium ion transport. Predicted to be located in plasma membrane and synapse. Predicted to be part of voltage-gated potassium channel complex. Expressed in head neurons; intestine; and sensory neurons. Used to study Jervell-Lange Nielsen syndrome. Human ortholog(s) of this gene implicated in heart conduction disease (multiple); long QT syndrome (multiple); and seminoma. Is an ortholog of human KCNQ1 (potassium voltage-gated channel subfamily Q member 1). WB:WBGene00002238 kars-1 Predicted to enable lysine-tRNA ligase activity and tRNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of nematode larval development; and regulation of brood size. Predicted to be located in cytosol and mitochondrion. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Expressed in tail. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate B and autosomal recessive nonsyndromic deafness 89. Is an ortholog of human KARS1 (lysyl-tRNA synthetase 1). WB:WBGene00002239 ksr-1 Enables mitogen-activated protein kinase kinase binding activity and protein kinase activity. Involved in several processes, including defense response to Gram-positive bacterium; myoblast migration; and positive regulation of vulval development. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Is an ortholog of human KSR1 (kinase suppressor of ras 1). WB:WBGene00002240 ksr-2 Enables protein kinase activity. Involved in several processes, including nematode male tail tip morphogenesis; positive regulation of vulval development; and vulval development. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Is an ortholog of human KSR1 (kinase suppressor of ras 1) and KSR2 (kinase suppressor of ras 2). WB:WBGene00002241 kup-1 Enriched in several structures, including AVK; MSaapaapa; accessory cell; anterior arcade cell; and g2 based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; glp-1; and gld-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including rotenone; mianserin; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00002242 kvs-1 Enables voltage-gated potassium channel activity. Involved in several processes, including forward locomotion; hyperosmotic response; and mechanosensory behavior. Part of voltage-gated potassium channel complex. Expressed in PDA; amphid neurons; anal depressor muscle; sperm; and ventral cord neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26. Is an ortholog of human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1). WB:WBGene00002243 lad-2 Enables semaphorin receptor activity. Involved in anterior/posterior axon guidance; dorsal/ventral axon guidance; and regulation of axon guidance. Located in plasma membrane. Expressed in lumbar neurons and nerve ring neurons. Used to study MASA syndrome. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; MASA syndrome; carcinoma (multiple); and pheochromocytoma. Is an ortholog of human L1CAM (L1 cell adhesion molecule). WB:WBGene00002244 laf-1 Enables RNA strand annealing activity; identical protein binding activity; and molecular condensate scaffold activity. Involved in several processes, including masculinization of hermaphroditic germ-line; positive regulation of embryonic development; and positive regulation of fertilization. Located in P granule. Expressed in germ line. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and syndromic X-linked intellectual disability. Is an ortholog of human DDX3X (DEAD-box helicase 3 X-linked) and DDX3Y (DEAD-box helicase 3 Y-linked). WB:WBGene00002245 lag-1 Enables Notch binding activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coactivator binding activity. Involved in several processes, including cell differentiation; dauer exit; and regulation of RNA metabolic process. Located in nucleus. Part of RNA polymerase II transcription regulator complex and chromatin. Expressed in several structures, including P4.p; P5.p; P6.p; P7.p; and P8.p. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome and dilated cardiomyopathy. Is an ortholog of human RBPJ (recombination signal binding protein for immunoglobulin kappa J region). WB:WBGene00002246 lag-2 Enables Notch binding activity. Involved in several processes, including maintenance of dauer; regulation of basement membrane organization; and regulation of cell population proliferation. Located in cell projection membrane and neuronal cell body membrane. Expressed in several structures, including distal tip cell; germ line; hypodermal cell; neurons; and vulval cell. WB:WBGene00002247 lam-1 Involved in pharynx development and positive regulation of locomotion. Located in basement membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including Pierson syndrome; amelogenesis imperfecta type 1A; and lung carcinoma (multiple). Is an ortholog of human LAMB1 (laminin subunit beta 1) and LAMB2 (laminin subunit beta 2). WB:WBGene00002248 lam-3 Predicted to be involved in animal organ morphogenesis and tissue development. Located in basement membrane. Expressed in several structures, including excretory canal; pharyngeal-intestinal valve; pharynx; somatic nervous system; and spermatheca. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy; congenital merosin-deficient muscular dystrophy 1A; and myopia. Is an ortholog of human LAMA1 (laminin subunit alpha 1) and LAMA2 (laminin subunit alpha 2). WB:WBGene00002249 lap-1 Enables identical protein binding activity. Involved in regulation of egg-laying behavior and regulation of growth rate. Predicted to be located in cytoplasm. Expressed in buccal cavity; intestine; and pharynx. Is an ortholog of human NPEPL1 (aminopeptidase like 1). WB:WBGene00002250 lap-2 Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. WB:WBGene00002251 lat-1 Enables endopeptidase activity. Involved in several processes, including anterior/posterior pattern specification; embryo development; and self proteolysis. Located in plasma membrane. Expressed in several structures, including ABarppaapa; AIY; Caaaaa; Caaaap; and pharynx. Is an ortholog of human ADGRL3 (adhesion G protein-coupled receptor L3). WB:WBGene00002252 lat-2 Enables endopeptidase activity. Involved in self proteolysis. Predicted to be located in plasma membrane. Expressed in excretory cell and pharynx. Is an ortholog of human ADGRL1 (adhesion G protein-coupled receptor L1) and ADGRL2 (adhesion G protein-coupled receptor L2). WB:WBGene00002253 lbp-1 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. WB:WBGene00002254 lbp-2 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. WB:WBGene00002255 lbp-3 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. WB:WBGene00002256 lbp-4 Predicted to enable lipid binding activity. WB:WBGene00002257 lbp-5 Enables fatty acid binding activity. Predicted to be involved in fatty acid transport. Located in nucleus and perinuclear region of cytoplasm. Expressed in hypodermis and tail. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1G; glioblastoma; and pre-eclampsia. Is an ortholog of several human genes including FABP4 (fatty acid binding protein 4); FABP7 (fatty acid binding protein 7); and PMP2 (peripheral myelin protein 2). WB:WBGene00002258 lbp-6 Predicted to enable fatty acid binding activity. Predicted to be involved in fatty acid transport. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Charcot-Marie-Tooth disease type 1G; Down syndrome; and artery disease (multiple). Is an ortholog of several human genes including FABP3 (fatty acid binding protein 3); FABP4 (fatty acid binding protein 4); and FABP7 (fatty acid binding protein 7). WB:WBGene00002259 lbp-7 Predicted to enable fatty acid binding activity. Predicted to be involved in fatty acid transport. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Charcot-Marie-Tooth disease type 1G; Down syndrome; and artery disease (multiple). Is an ortholog of several human genes including FABP3 (fatty acid binding protein 3); FABP7 (fatty acid binding protein 7); and PMP2 (peripheral myelin protein 2). WB:WBGene00002260 lbp-8 Enables long-chain fatty acid transporter activity and oleic acid binding activity. Involved in long-chain fatty acid transport. Located in lysosome and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 1G; glioblastoma; and pre-eclampsia. Is an ortholog of several human genes including FABP7 (fatty acid binding protein 7); FABP9 (fatty acid binding protein 9); and PMP2 (peripheral myelin protein 2). WB:WBGene00002261 ldb-1 Enables DNA-binding transcription factor activity; DNA-binding transcription factor binding activity; and LIM domain binding activity. Involved in several processes, including mechanosensory behavior; positive regulation of vulval development; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Expressed in several structures, including AIY; body wall musculature; gonad; neurons; and vulval muscle. WB:WBGene00002262 ldh-1 Predicted to enable L-lactate dehydrogenase activity. Predicted to be involved in lactate metabolic process and pyruvate metabolic process. Predicted to be located in mitochondrion. Expressed in tail. Is an ortholog of several human genes including LDHA (lactate dehydrogenase A); LDHB (lactate dehydrogenase B); and LDHC (lactate dehydrogenase C). WB:WBGene00002263 lea-1 Predicted to enable lipid binding activity. Involved in hyperosmotic response; response to desiccation; and response to heat. Predicted to be located in extracellular region. Expressed in several structures, including excretory cell; head; intestine; pharynx; and tail neurons. Is an ortholog of human PLIN4 (perilipin 4). WB:WBGene00002264 lec-1 Enables galactoside binding activity. Located in collagen and cuticulin-based cuticle extracellular matrix. Is an ortholog of human LGALS9 (galectin 9) and LGALS9B (galectin 9B). WB:WBGene00002265 lec-2 Predicted to enable galactoside binding activity. Located in membrane raft and plasma membrane. WB:WBGene00002266 lec-3 Predicted to enable galactoside binding activity. Located in plasma membrane. Is an ortholog of human LGALS9 (galectin 9) and LGALS9B (galectin 9B). WB:WBGene00002267 lec-4 Enables galactoside binding activity. Located in membrane raft. Is an ortholog of human LGALS9 (galectin 9) and LGALS9B (galectin 9B). WB:WBGene00002268 lec-5 Predicted to enable galactoside binding activity. Located in membrane raft. Is an ortholog of human LGALS9 (galectin 9); LGALS9B (galectin 9B); and LGALS9C (galectin 9C). WB:WBGene00002269 lec-6 Predicted to enable galactoside binding activity. Located in cytoplasm. Expressed in intestine and pharynx. Is an ortholog of human LGALS7 (galectin 7) and LGALS7B (galectin 7B). WB:WBGene00002270 lec-7 Predicted to enable galactoside binding activity. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; aortic valve stenosis; and liver cirrhosis. Is an ortholog of human LGALS3 (galectin 3). WB:WBGene00002271 lec-8 Enables glycolipid binding activity. Involved in response to toxic substance. Located in cytoplasmic vesicle. Expressed in intestine; pharyngeal-intestinal valve; tail; virL; and virR. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; aortic valve stenosis; and liver cirrhosis. Is an ortholog of human LGALS3 (galectin 3). WB:WBGene00002272 lec-9 Enables glycolipid binding activity. Located in cytoplasm. WB:WBGene00002273 lec-10 Enables glycolipid binding activity. Located in apical part of cell and cytoplasm. Expressed in intestine. WB:WBGene00002274 lec-11 Predicted to enable galactoside binding activity. Involved in innate immune response. Located in cytoplasm. WB:WBGene00002275 lem-2 Enables chromatin DNA binding activity and lamin binding activity. Involved in several processes, including mitotic cytokinesis; organelle organization; and response to X-ray. Located in chromosome and nuclear envelope. Used to study Emery-Dreifuss muscular dystrophy and cataract 46 juvenile-onset. Human ortholog(s) of this gene implicated in Buschke-Ollendorff syndrome and cataract 46 juvenile-onset. Is an ortholog of human LEMD2 (LEM domain nuclear envelope protein 2) and LEMD3 (LEM domain containing 3). WB:WBGene00002276 lem-3 Enables DNA endonuclease activity. Involved in several processes, including DNA metabolic process; cellular response to hydroxyurea; and response to radiation. Located in several cellular components, including condensed chromosome; midbody; and mitotic spindle midzone. Expressed in embryonic cell. Is an ortholog of human ANKLE1 (ankyrin repeat and LEM domain containing 1). WB:WBGene00002278 lep-2 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm. Expressed in developing hermaphrodite gonad; hypodermis; neurons; and pharynx. Human ortholog(s) of this gene implicated in central precocious puberty 2. Is an ortholog of several human genes including MKRN1 (makorin ring finger protein 1); MKRN3 (makorin ring finger protein 3); and MKRN4P (makorin ring finger protein 4, pseudogene). WB:WBGene00002279 let-1 Acts upstream of or within embryo development and nematode larval development. WB:WBGene00002280 let-2 An extracellular matrix structural constituent conferring tensile strength. Involved in several processes, including embryo development; gonad morphogenesis; and regulation of distal tip cell migration. Located in basement membrane. Part of collagen type IV trimer. Expressed in several structures, including coelomocyte; egg-laying apparatus; rectal muscle; spermatheca; and tail. Human ortholog(s) of this gene implicated in several diseases, including X-linked Alport syndrome; X-linked deafness 6; and artery disease (multiple). Is an ortholog of human COL4A1 (collagen type IV alpha 1 chain); COL4A5 (collagen type IV alpha 5 chain); and COL4A6 (collagen type IV alpha 6 chain). WB:WBGene00002281 let-3 Acts upstream of or within nematode larval development. WB:WBGene00002282 let-4 Involved in several processes, including epithelial cell development; nematode larval development; and positive regulation of membrane permeability. Located in apical part of cell. Expressed in excretory system; hypodermis; rectal epithelial cell; and vulva. WB:WBGene00002283 let-5 Acts upstream of or within nematode larval development. WB:WBGene00002284 let-6 Acts upstream of or within nematode larval development. WB:WBGene00002285 let-7 Enables mRNA 3'-UTR binding activity. Involved in several processes, including negative regulation of Ras protein signal transduction; negative regulation of gene expression; and regulation of development, heterochronic. Part of RISC complex. Expressed in several structures, including gonad; hypodermis; somatic nervous system; touch receptor neurons; and vulval precursor cell. Used to study cancer. WB:WBGene00002286 let-9 No description available WB:WBGene00002287 let-10 No description available WB:WBGene00002288 let-11 No description available WB:WBGene00002289 let-12 No description available WB:WBGene00002290 let-13 No description available WB:WBGene00002291 let-14 No description available WB:WBGene00002292 let-15 No description available WB:WBGene00002293 let-16 No description available WB:WBGene00002294 let-18 No description available WB:WBGene00002295 let-19 Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Expressed in several structures, including TL.a; TL.p; TR.a; TR.p; and seam cell. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder and dextro-looped transposition of the great arteries. Is an ortholog of human MED13 (mediator complex subunit 13) and MED13L (mediator complex subunit 13L). WB:WBGene00002296 let-20 No description available WB:WBGene00002297 ect-2 Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; mitotic cytokinesis; and regulation of actin filament-based process. Located in cell cortex. Expressed in several structures, including P1.p; germ line; hermaphrodite gonad; neuroblasts; and somatic gonad precursor. Is an ortholog of human ECT2 (epithelial cell transforming 2). WB:WBGene00002298 let-22 No description available WB:WBGene00002299 let-23 Enables epidermal growth factor receptor activity. Involved in several processes, including determination of adult lifespan; positive regulation of vulval development; and vulval cell fate specification. Located in cell-cell junction and plasma membrane. Expressed in several structures, including apoptotic cell; egg-laying apparatus; excretory duct cell; head; and vulval precursor cell. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hypertension (multiple); and reproductive organ cancer (multiple). Is an ortholog of human EGFR (epidermal growth factor receptor) and ERBB4 (erb-b2 receptor tyrosine kinase 4). WB:WBGene00002300 let-24 No description available WB:WBGene00002301 let-25 No description available WB:WBGene00002302 let-26 No description available WB:WBGene00002303 let-27 No description available WB:WBGene00002304 let-28 No description available WB:WBGene00002305 let-30 No description available WB:WBGene00002306 let-31 No description available WB:WBGene00002307 let-32 No description available WB:WBGene00002308 let-33 No description available WB:WBGene00002309 let-34 No description available WB:WBGene00002310 let-35 No description available WB:WBGene00002311 let-36 No description available WB:WBGene00002312 let-37 No description available WB:WBGene00002313 let-38 No description available WB:WBGene00002314 let-39 No description available WB:WBGene00002315 let-40 No description available WB:WBGene00002316 let-41 No description available WB:WBGene00002318 let-43 No description available WB:WBGene00002319 let-44 No description available WB:WBGene00002320 let-45 No description available WB:WBGene00002321 let-46 No description available WB:WBGene00002322 let-47 No description available WB:WBGene00002323 let-48 No description available WB:WBGene00002324 let-49 Predicted to enable transcription coregulator activity. Involved in embryo development and reproduction. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is an ortholog of human MED7 (mediator complex subunit 7). WB:WBGene00002325 let-50 No description available WB:WBGene00002326 let-51 No description available WB:WBGene00002327 let-52 No description available WB:WBGene00002328 let-53 No description available WB:WBGene00002329 let-54 No description available WB:WBGene00002330 let-55 No description available WB:WBGene00002331 let-56 No description available WB:WBGene00002332 let-57 No description available WB:WBGene00002333 let-58 No description available WB:WBGene00002334 let-59 No description available WB:WBGene00002335 let-60 Enables GTP binding activity; phospholipase binding activity; and protein serine/threonine kinase binding activity. Involved in several processes, including learning or memory; positive regulation of receptor localization to synapse; and positive regulation of vulval development. Located in cell cortex. Expressed in several structures, including germ line; gonad; head neurons; pharyngeal muscle cell; and vulval cell. Used to study RASopathy and prostate cancer. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); hematologic cancer (multiple); and malignant astrocytoma (multiple). Is an ortholog of human HRAS (HRas proto-oncogene, GTPase). WB:WBGene00002336 let-61 No description available WB:WBGene00002337 let-63 No description available WB:WBGene00002338 let-64 No description available WB:WBGene00002340 let-66 No description available WB:WBGene00002341 let-67 No description available WB:WBGene00002342 let-68 No description available WB:WBGene00002343 let-69 No description available WB:WBGene00002344 let-70 Enables ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Involved in programmed cell death involved in cell development; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of ubiquitin ligase complex. Expressed in several structures, including P1; P2; linker cell; ventral ganglion; and ventral nerve cord. Is an ortholog of human UBE2D2 (ubiquitin conjugating enzyme E2 D2) and UBE2D3 (ubiquitin conjugating enzyme E2 D3). WB:WBGene00002345 let-71 No description available WB:WBGene00002346 let-72 No description available WB:WBGene00002347 let-73 No description available WB:WBGene00002348 myo-1 A structural constituent of muscle. Involved in muscle contraction and pharyngeal pumping. Located in striated muscle myosin thick filament. Expressed in pharynx. Human ortholog(s) of this gene implicated in several diseases, including contractures, pterygia, and spondylocarpotarsal fusion syndrome 1A; distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3). WB:WBGene00002349 let-78 No description available WB:WBGene00002350 let-79 No description available WB:WBGene00002351 let-80 No description available WB:WBGene00002352 let-81 No description available WB:WBGene00002353 let-82 No description available WB:WBGene00002354 let-83 No description available WB:WBGene00002355 let-84 No description available WB:WBGene00002356 let-85 No description available WB:WBGene00002357 let-86 No description available WB:WBGene00002358 let-87 No description available WB:WBGene00002359 let-88 No description available WB:WBGene00002360 let-89 No description available WB:WBGene00002361 let-90 No description available WB:WBGene00002362 let-91 No description available WB:WBGene00002363 let-92 Enables DEAD/H-box RNA helicase binding activity. Involved in organelle organization. Located in several cellular components, including axonal growth cone; centrosome; and neuronal cell body. Part of protein phosphatase type 2A complex. Human ortholog(s) of this gene implicated in Parkinson's disease; congestive heart failure; and prostate cancer. Is an ortholog of human PPP2CA (protein phosphatase 2 catalytic subunit alpha) and PPP2CB (protein phosphatase 2 catalytic subunit beta). WB:WBGene00002364 let-93 No description available WB:WBGene00002365 let-96 No description available WB:WBGene00002366 let-97 No description available WB:WBGene00002367 let-98 No description available WB:WBGene00002368 let-99 Involved in establishment of mitotic spindle orientation. Located in cell cortex. Expressed in embryonic cell. WB:WBGene00002369 let-100 No description available WB:WBGene00002371 let-102 No description available WB:WBGene00002374 let-105 No description available WB:WBGene00002375 let-106 No description available WB:WBGene00002376 let-107 No description available WB:WBGene00002378 let-109 No description available WB:WBGene00002379 let-110 No description available WB:WBGene00002380 let-111 No description available WB:WBGene00002381 let-112 No description available WB:WBGene00002382 let-113 No description available WB:WBGene00002383 let-114 No description available WB:WBGene00002384 let-115 No description available WB:WBGene00002385 let-116 No description available WB:WBGene00002386 let-117 No description available WB:WBGene00002387 let-118 No description available WB:WBGene00002388 let-119 No description available WB:WBGene00002389 let-120 No description available WB:WBGene00002390 let-121 No description available WB:WBGene00002391 let-122 No description available WB:WBGene00002392 let-123 No description available WB:WBGene00002393 lpr-1 Involved in nematode larval development and tube development. Predicted to be located in extracellular region. Expressed in several structures, including P1; P12; P2; excretory system; and hypodermal cell. WB:WBGene00002394 let-125 No description available WB:WBGene00002395 let-126 No description available WB:WBGene00002396 let-127 No description available WB:WBGene00002397 let-128 No description available WB:WBGene00002399 let-130 No description available WB:WBGene00002400 let-131 No description available WB:WBGene00002401 let-132 No description available WB:WBGene00002402 let-133 No description available WB:WBGene00002403 let-134 No description available WB:WBGene00002404 let-135 No description available WB:WBGene00002405 let-136 No description available WB:WBGene00002406 let-137 No description available WB:WBGene00002407 let-138 No description available WB:WBGene00002408 let-139 No description available WB:WBGene00002409 let-140 No description available WB:WBGene00002410 let-141 No description available WB:WBGene00002411 let-142 No description available WB:WBGene00002412 let-143 No description available WB:WBGene00002413 let-144 No description available WB:WBGene00002414 let-145 No description available WB:WBGene00002415 let-146 No description available WB:WBGene00002417 let-148 No description available WB:WBGene00002418 let-149 No description available WB:WBGene00002419 let-150 No description available WB:WBGene00002420 let-151 No description available WB:WBGene00002422 let-153 No description available WB:WBGene00002423 let-154 No description available WB:WBGene00002424 let-155 No description available WB:WBGene00002425 let-156 No description available WB:WBGene00002426 let-157 No description available WB:WBGene00002427 let-158 No description available WB:WBGene00002428 let-159 No description available WB:WBGene00002429 let-160 No description available WB:WBGene00002430 let-161 No description available WB:WBGene00002431 let-162 No description available WB:WBGene00002432 let-163 No description available WB:WBGene00002433 let-164 No description available WB:WBGene00002434 let-170 No description available WB:WBGene00002435 let-171 No description available WB:WBGene00002436 let-172 No description available WB:WBGene00002437 let-173 No description available WB:WBGene00002438 let-174 No description available WB:WBGene00002439 let-175 No description available WB:WBGene00002440 let-176 No description available WB:WBGene00002441 let-178 No description available WB:WBGene00002442 let-179 No description available WB:WBGene00002443 let-180 No description available WB:WBGene00002444 let-181 No description available WB:WBGene00002445 let-182 No description available WB:WBGene00002446 let-183 No description available WB:WBGene00002447 let-184 No description available WB:WBGene00002448 let-185 No description available WB:WBGene00002449 let-186 No description available WB:WBGene00002450 let-187 No description available WB:WBGene00002451 let-188 No description available WB:WBGene00002452 let-189 No description available WB:WBGene00002453 let-190 No description available WB:WBGene00002454 let-191 No description available WB:WBGene00002455 let-192 No description available WB:WBGene00002456 let-193 No description available WB:WBGene00002457 let-201 No description available WB:WBGene00002458 let-202 No description available WB:WBGene00002459 let-203 No description available WB:WBGene00002460 let-204 No description available WB:WBGene00002461 let-205 No description available WB:WBGene00002462 let-206 No description available WB:WBGene00002463 let-207 No description available WB:WBGene00002464 let-208 No description available WB:WBGene00002465 let-236 No description available WB:WBGene00002466 let-237 Acts upstream of or within embryo development. WB:WBGene00002467 let-238 No description available WB:WBGene00002468 let-239 No description available WB:WBGene00002469 let-240 No description available WB:WBGene00002470 let-241 No description available WB:WBGene00002471 let-242 No description available WB:WBGene00002472 let-243 No description available WB:WBGene00002473 let-244 No description available WB:WBGene00002474 let-245 No description available WB:WBGene00002475 let-246 No description available WB:WBGene00002476 let-247 No description available WB:WBGene00002477 let-248 No description available WB:WBGene00002478 let-249 No description available WB:WBGene00002479 let-250 No description available WB:WBGene00002480 let-251 No description available WB:WBGene00002481 let-252 No description available WB:WBGene00002482 let-253 No description available WB:WBGene00002483 let-254 No description available WB:WBGene00002484 let-255 No description available WB:WBGene00002485 let-256 No description available WB:WBGene00002486 let-257 No description available WB:WBGene00002487 let-258 No description available WB:WBGene00002488 let-259 No description available WB:WBGene00002489 let-260 No description available WB:WBGene00002490 let-261 No description available WB:WBGene00002491 let-262 No description available WB:WBGene00002492 let-263 No description available WB:WBGene00002493 let-264 No description available WB:WBGene00002494 let-265 No description available WB:WBGene00002495 let-266 No description available WB:WBGene00002496 let-267 No description available WB:WBGene00002497 let-268 Enables UDP-glucose:glycoprotein glucosyltransferase activity. Involved in collagen biosynthetic process and protein glycosylation. Predicted to be located in endoplasmic reticulum. Expressed in GLR and body wall musculature. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome kyphoscoliotic type 1; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1). WB:WBGene00002498 let-269 No description available WB:WBGene00002499 let-270 No description available WB:WBGene00002500 let-271 No description available WB:WBGene00002501 let-272 No description available WB:WBGene00002502 let-273 No description available WB:WBGene00002503 let-274 No description available WB:WBGene00002504 let-275 No description available WB:WBGene00002505 let-276 No description available WB:WBGene00002506 let-277 No description available WB:WBGene00002507 let-278 No description available WB:WBGene00002508 let-279 No description available WB:WBGene00002509 let-280 No description available WB:WBGene00002510 let-281 No description available WB:WBGene00002511 let-282 No description available WB:WBGene00002512 let-284 No description available WB:WBGene00002513 let-285 No description available WB:WBGene00002514 let-286 No description available WB:WBGene00002515 let-287 No description available WB:WBGene00002516 let-288 No description available WB:WBGene00002517 let-289 No description available WB:WBGene00002518 let-290 No description available WB:WBGene00002519 let-291 No description available WB:WBGene00002520 let-292 No description available WB:WBGene00002521 let-293 No description available WB:WBGene00002522 let-294 No description available WB:WBGene00002523 let-295 No description available WB:WBGene00002524 let-296 No description available WB:WBGene00002525 let-297 No description available WB:WBGene00002526 let-298 No description available WB:WBGene00002527 let-301 No description available WB:WBGene00002528 let-302 No description available WB:WBGene00002529 let-303 No description available WB:WBGene00002530 let-304 No description available WB:WBGene00002531 let-305 No description available WB:WBGene00002532 let-306 No description available WB:WBGene00002533 let-307 No description available WB:WBGene00002534 let-308 No description available WB:WBGene00002535 let-309 No description available WB:WBGene00002536 let-311 No description available WB:WBGene00002537 let-312 No description available WB:WBGene00002538 let-313 No description available WB:WBGene00002539 let-314 No description available WB:WBGene00002540 let-315 No description available WB:WBGene00002541 let-316 No description available WB:WBGene00002542 let-317 No description available WB:WBGene00002543 let-318 No description available WB:WBGene00002544 let-319 No description available WB:WBGene00002545 let-320 No description available WB:WBGene00002546 let-321 No description available WB:WBGene00002547 let-322 No description available WB:WBGene00002548 let-323 No description available WB:WBGene00002549 let-324 No description available WB:WBGene00002550 let-325 No description available WB:WBGene00002551 let-326 No description available WB:WBGene00002552 let-327 No description available WB:WBGene00002553 let-329 No description available WB:WBGene00002555 let-331 No description available WB:WBGene00002556 let-332 No description available WB:WBGene00002557 let-334 No description available WB:WBGene00002558 let-335 No description available WB:WBGene00002559 let-336 No description available WB:WBGene00002560 let-337 No description available WB:WBGene00002561 let-338 No description available WB:WBGene00002562 let-339 No description available WB:WBGene00002563 let-340 No description available WB:WBGene00002564 let-342 No description available WB:WBGene00002565 let-343 No description available WB:WBGene00002566 let-344 No description available WB:WBGene00002567 let-345 No description available WB:WBGene00002568 let-346 No description available WB:WBGene00002569 let-347 No description available WB:WBGene00002570 let-348 No description available WB:WBGene00002571 let-349 No description available WB:WBGene00002572 let-350 Acts upstream of or within reproduction. WB:WBGene00002573 let-351 No description available WB:WBGene00002574 let-352 No description available WB:WBGene00002575 let-353 No description available WB:WBGene00002577 let-356 No description available WB:WBGene00002578 let-357 No description available WB:WBGene00002579 let-359 No description available WB:WBGene00002580 let-360 No description available WB:WBGene00002581 let-361 No description available WB:WBGene00002583 let-363 Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including box C/D snoRNP assembly; determination of adult lifespan; and regulation of gene expression. Located in cytoplasm. Part of TORC1 complex and TORC2 complex. Expressed in several structures, including intestine; muscle cell; neurons; pharynx; and vulva. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); interstitial cystitis; and kidney angiomyolipoma. Is an ortholog of human MTOR (mechanistic target of rapamycin kinase). WB:WBGene00002587 let-367 No description available WB:WBGene00002589 let-369 No description available WB:WBGene00002591 let-371 No description available WB:WBGene00002592 let-372 No description available WB:WBGene00002593 let-373 No description available WB:WBGene00002594 let-374 No description available WB:WBGene00002595 let-375 No description available WB:WBGene00002596 let-376 No description available WB:WBGene00002601 let-381 Enables sequence-specific DNA binding activity. Involved in mesodermal cell fate specification; nematode larval development; and positive regulation of mesodermal cell fate specification. Located in nucleus. Expressed in M.dlp; M.drp; body wall muscle cell from M lineage; and coelomocyte. Human ortholog(s) of this gene implicated in persistent fetal circulation syndrome. Is an ortholog of human FOXF1 (forkhead box F1). WB:WBGene00002607 let-387 No description available WB:WBGene00002608 let-388 No description available WB:WBGene00002610 let-390 No description available WB:WBGene00002612 let-392 No description available WB:WBGene00002613 let-393 No description available WB:WBGene00002614 let-394 No description available WB:WBGene00002615 let-395 No description available WB:WBGene00002618 let-398 No description available WB:WBGene00002619 let-399 No description available WB:WBGene00002621 let-401 No description available WB:WBGene00002622 let-402 No description available WB:WBGene00002623 let-403 No description available WB:WBGene00002624 let-404 No description available WB:WBGene00002625 let-405 No description available WB:WBGene00002626 let-406 No description available WB:WBGene00002627 let-407 No description available WB:WBGene00002628 let-408 No description available WB:WBGene00002629 let-409 No description available WB:WBGene00002630 let-410 No description available WB:WBGene00002631 let-411 No description available WB:WBGene00002632 let-413 Involved in several processes, including adherens junction assembly; embryonic digestive tract morphogenesis; and maintenance of epithelial cell apical/basal polarity. Located in basolateral plasma membrane. Expressed in epithelial cell; nerve ring; rectum; and spermatheca. Is an ortholog of human SCRIB (scribble planar cell polarity protein). WB:WBGene00002633 let-414 No description available WB:WBGene00002634 let-415 No description available WB:WBGene00002635 let-416 No description available WB:WBGene00002636 let-417 No description available WB:WBGene00002637 let-418 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in embryonic digestive tract morphogenesis; negative regulation of transcription by RNA polymerase II; and negative regulation of vulval development. Part of RNA polymerase II transcription repressor complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; gonad; and somatic nervous system. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung adenocarcinoma; and lymphoma. Is an ortholog of human CHD3 (chromodomain helicase DNA binding protein 3). WB:WBGene00002638 let-419 No description available WB:WBGene00002639 let-420 No description available WB:WBGene00002640 let-421 No description available WB:WBGene00002641 let-422 No description available WB:WBGene00002642 let-423 No description available WB:WBGene00002643 let-424 No description available WB:WBGene00002644 let-426 No description available WB:WBGene00002645 let-427 No description available WB:WBGene00002646 let-428 No description available WB:WBGene00002647 let-429 No description available WB:WBGene00002648 let-430 No description available WB:WBGene00002649 let-431 No description available WB:WBGene00002650 let-433 No description available WB:WBGene00002651 let-434 No description available WB:WBGene00002652 let-436 No description available WB:WBGene00002653 let-437 No description available WB:WBGene00002654 let-438 No description available WB:WBGene00002655 let-439 No description available WB:WBGene00002656 let-440 No description available WB:WBGene00002657 let-441 No description available WB:WBGene00002658 let-442 No description available WB:WBGene00002659 let-443 No description available WB:WBGene00002660 let-444 No description available WB:WBGene00002661 let-445 No description available WB:WBGene00002662 let-447 No description available WB:WBGene00002663 let-448 No description available WB:WBGene00002664 let-449 No description available WB:WBGene00002665 let-450 No description available WB:WBGene00002666 let-452 No description available WB:WBGene00002667 let-453 No description available WB:WBGene00002668 let-454 No description available WB:WBGene00002669 let-455 No description available WB:WBGene00002670 let-456 No description available WB:WBGene00002671 let-458 No description available WB:WBGene00002672 let-459 No description available WB:WBGene00002673 let-460 No description available WB:WBGene00002675 let-463 No description available WB:WBGene00002676 let-464 No description available WB:WBGene00002677 let-466 No description available WB:WBGene00002678 let-467 No description available WB:WBGene00002679 let-468 No description available WB:WBGene00002680 let-469 No description available WB:WBGene00002681 let-470 No description available WB:WBGene00002682 let-471 No description available WB:WBGene00002683 let-472 No description available WB:WBGene00002684 let-473 No description available WB:WBGene00002685 let-474 No description available WB:WBGene00002686 let-475 No description available WB:WBGene00002687 let-476 No description available WB:WBGene00002688 let-478 No description available WB:WBGene00002689 let-479 No description available WB:WBGene00002690 let-480 No description available WB:WBGene00002691 let-481 No description available WB:WBGene00002692 let-500 No description available WB:WBGene00002693 let-501 No description available WB:WBGene00002694 let-502 Predicted to enable Rho-dependent protein serine/threonine kinase activity. Involved in several processes, including embryonic body morphogenesis; pharyngeal gland morphogenesis; and pharynx development. Located in adherens junction; contractile fiber; and nucleus. Expressed in several structures, including P3.p hermaphrodite; Z2; Z3; gonad; and hypodermis. Is an ortholog of human ROCK1 (Rho associated coiled-coil containing protein kinase 1) and ROCK2 (Rho associated coiled-coil containing protein kinase 2). WB:WBGene00002696 let-504 Predicted to enable chromatin binding activity. Predicted to be involved in regulation of gene expression. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability. Is an ortholog of human NKAP (NFKB activating protein). WB:WBGene00002697 let-505 No description available WB:WBGene00002698 let-506 No description available WB:WBGene00002699 let-507 No description available WB:WBGene00002700 let-508 No description available WB:WBGene00002702 let-510 No description available WB:WBGene00002703 let-511 No description available WB:WBGene00002704 let-513 No description available WB:WBGene00002705 let-514 No description available WB:WBGene00002706 let-515 No description available WB:WBGene00002707 let-516 No description available WB:WBGene00002709 let-518 No description available WB:WBGene00002711 let-520 No description available WB:WBGene00002712 let-521 No description available WB:WBGene00002714 let-523 No description available WB:WBGene00002715 let-524 No description available WB:WBGene00002716 let-525 No description available WB:WBGene00002717 let-526 Predicted to enable DNA binding activity. Predicted to contribute to nucleosome binding activity. Involved in gonad development; nematode larval development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including excretory cell; gonad; pharynx; tail precursor cell; and vulva. Used to study alcohol use disorder and cancer. Human ortholog(s) of this gene implicated in several diseases, including Coffin-Siris syndrome (multiple); carcinoma (multiple); and pre-eclampsia. Is an ortholog of human ARID1A (AT-rich interaction domain 1A). WB:WBGene00002719 let-528 No description available WB:WBGene00002721 let-530 No description available WB:WBGene00002723 let-532 No description available WB:WBGene00002724 let-533 No description available WB:WBGene00002726 let-535 No description available WB:WBGene00002727 let-536 No description available WB:WBGene00002728 let-538 No description available WB:WBGene00002729 let-539 No description available WB:WBGene00002730 let-540 No description available WB:WBGene00002731 let-541 No description available WB:WBGene00002732 let-542 No description available WB:WBGene00002733 let-543 No description available WB:WBGene00002734 let-544 No description available WB:WBGene00002735 let-545 No description available WB:WBGene00002736 let-546 No description available WB:WBGene00002737 let-547 No description available WB:WBGene00002738 let-548 No description available WB:WBGene00002739 let-549 No description available WB:WBGene00002740 let-550 No description available WB:WBGene00002741 let-551 No description available WB:WBGene00002742 let-552 No description available WB:WBGene00002743 let-554 No description available WB:WBGene00002744 let-555 No description available WB:WBGene00002745 let-556 No description available WB:WBGene00002746 let-557 No description available WB:WBGene00002747 let-558 No description available WB:WBGene00002748 let-559 No description available WB:WBGene00002749 let-560 No description available WB:WBGene00002750 let-571 No description available WB:WBGene00002751 let-572 No description available WB:WBGene00002752 let-573 No description available WB:WBGene00002753 let-574 No description available WB:WBGene00002756 let-577 No description available WB:WBGene00002757 let-578 No description available WB:WBGene00002758 let-579 No description available WB:WBGene00002759 let-580 No description available WB:WBGene00002761 let-582 No description available WB:WBGene00002762 let-583 No description available WB:WBGene00002763 let-584 No description available WB:WBGene00002765 let-586 No description available WB:WBGene00002766 let-587 No description available WB:WBGene00002767 let-588 No description available WB:WBGene00002768 let-589 No description available WB:WBGene00002769 let-590 No description available WB:WBGene00002770 let-592 No description available WB:WBGene00002771 let-593 No description available WB:WBGene00002776 let-598 No description available WB:WBGene00002778 let-600 No description available WB:WBGene00002783 let-607 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including regulation of distal tip cell migration; regulation of establishment of cell polarity; and regulation of signal transduction. Part of chromatin. Expressed in several structures, including coelomocyte; excretory cell; gonad; pseudocoelom; and somatic cell. WB:WBGene00002785 let-609 No description available WB:WBGene00002786 let-610 No description available WB:WBGene00002789 let-613 No description available WB:WBGene00002790 let-614 No description available WB:WBGene00002791 let-615 No description available WB:WBGene00002792 let-618 No description available WB:WBGene00002793 let-619 No description available WB:WBGene00002794 let-620 No description available WB:WBGene00002795 let-621 No description available WB:WBGene00002796 let-622 No description available WB:WBGene00002797 let-623 No description available WB:WBGene00002798 let-624 No description available WB:WBGene00002799 let-625 No description available WB:WBGene00002800 let-626 No description available WB:WBGene00002801 let-627 No description available WB:WBGene00002802 let-628 No description available WB:WBGene00002803 let-629 No description available WB:WBGene00002804 let-630 Predicted to enable rRNA binding activity and ribosomal small subunit binding activity. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 51. Is an ortholog of human PTCD3 (pentatricopeptide repeat domain 3). WB:WBGene00002806 let-632 No description available WB:WBGene00002807 let-633 No description available WB:WBGene00002808 let-634 No description available WB:WBGene00002809 let-635 No description available WB:WBGene00002810 let-636 No description available WB:WBGene00002811 let-637 No description available WB:WBGene00002812 let-638 No description available WB:WBGene00002813 let-639 No description available WB:WBGene00002814 let-640 No description available WB:WBGene00002815 let-641 No description available WB:WBGene00002816 let-642 No description available WB:WBGene00002817 let-643 No description available WB:WBGene00002818 let-644 No description available WB:WBGene00002819 let-645 No description available WB:WBGene00002821 let-647 No description available WB:WBGene00002822 let-648 No description available WB:WBGene00002823 let-649 No description available WB:WBGene00002824 let-650 No description available WB:WBGene00002825 let-651 No description available WB:WBGene00002826 let-652 No description available WB:WBGene00002827 let-653 A structural constituent of cuticle. Involved in several processes, including cuticle pattern formation; embryonic ectodermal digestive tract morphogenesis; and regulation of developmental process. Located in apical plasma membrane; extracellular space; and supramolecular fiber. Expressed in excretory duct cell; excretory socket cell; rectal epithelial cell; and vulval cell. WB:WBGene00002828 let-655 No description available WB:WBGene00002829 let-656 No description available WB:WBGene00002830 let-657 No description available WB:WBGene00002831 let-658 No description available WB:WBGene00002832 let-659 No description available WB:WBGene00002833 let-660 No description available WB:WBGene00002834 let-661 No description available WB:WBGene00002835 let-662 No description available WB:WBGene00002836 let-664 No description available WB:WBGene00002837 let-700 No description available WB:WBGene00002838 let-702 No description available WB:WBGene00002839 let-704 No description available WB:WBGene00002840 let-705 No description available WB:WBGene00002841 let-706 No description available WB:WBGene00002842 let-707 No description available WB:WBGene00002843 let-709 No description available WB:WBGene00002844 let-710 No description available WB:WBGene00002845 let-711 Predicted to enable molecular adaptor activity. Involved in several processes, including microtubule cytoskeleton organization; nematode larval development; and nuclear-transcribed mRNA poly(A) tail shortening. Located in cytoplasm. Part of CCR4-NOT complex. Expressed in germ line; gonad; and in male. Human ortholog(s) of this gene implicated in holoprosencephaly. Is an ortholog of human CNOT1 (CCR4-NOT transcription complex subunit 1). WB:WBGene00002846 let-712 No description available WB:WBGene00002847 let-713 No description available WB:WBGene00002848 let-714 No description available WB:WBGene00002849 let-715 No description available WB:WBGene00002850 let-716 Predicted to enable RNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human PDCD11 (programmed cell death 11). WB:WBGene00002851 let-717 No description available WB:WBGene00002852 let-718 No description available WB:WBGene00002853 let-719 No description available WB:WBGene00002854 let-720 No description available WB:WBGene00002855 let-721 Predicted to enable electron-transferring-flavoprotein dehydrogenase activity. Predicted to be involved in electron transport chain. Located in mitochondrion. Expressed in gonad; hypodermis; spermatheca; tail; and vas deferens. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Is an ortholog of human ETFDH (electron transfer flavoprotein dehydrogenase). WB:WBGene00002856 let-722 No description available WB:WBGene00002857 let-723 No description available WB:WBGene00002858 let-724 No description available WB:WBGene00002859 let-725 No description available WB:WBGene00002860 let-727 No description available WB:WBGene00002861 let-728 No description available WB:WBGene00002862 let-729 No description available WB:WBGene00002863 let-730 No description available WB:WBGene00002864 let-732 No description available WB:WBGene00002865 let-733 No description available WB:WBGene00002866 let-734 No description available WB:WBGene00002867 let-736 No description available WB:WBGene00002868 let-737 No description available WB:WBGene00002869 let-738 No description available WB:WBGene00002870 let-739 No description available WB:WBGene00002871 let-741 No description available WB:WBGene00002872 let-743 No description available WB:WBGene00002873 let-746 No description available WB:WBGene00002874 let-747 No description available WB:WBGene00002875 let-748 No description available WB:WBGene00002876 let-750 No description available WB:WBGene00002877 let-752 No description available WB:WBGene00002878 let-753 No description available WB:WBGene00002879 let-754 Predicted to enable adenylate kinase activity. Involved in negative regulation of protein kinase C signaling and regulation of establishment of cell polarity. Predicted to be located in mitochondrion. Expressed in head and tail. Human ortholog(s) of this gene implicated in reticular dysgenesis. Is an ortholog of human AK2 (adenylate kinase 2). WB:WBGene00002880 let-755 No description available WB:WBGene00002881 let-756 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; growth factor activity; and protein kinase binding activity. Involved in fibroblast growth factor receptor signaling pathway; nematode larval development; and regulation of cellular component organization. Located in cytoplasm; extracellular space; and nuclear lumen. Expressed in several structures, including CAN; OLL; cephalic sensillum; muscle cell; and pharyngeal cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; brain disease (multiple); carcinoma (multiple); and eye disease (multiple). Is an ortholog of human FGF3 (fibroblast growth factor 3). WB:WBGene00002882 let-758 No description available WB:WBGene00002883 let-759 No description available WB:WBGene00002884 let-760 No description available WB:WBGene00002885 let-761 No description available WB:WBGene00002886 let-762 No description available WB:WBGene00002887 let-763 No description available WB:WBGene00002888 let-764 No description available WB:WBGene00002889 let-765 Predicted to enable chromatin DNA binding activity and histone binding activity. Involved in several processes, including nematode male tail tip morphogenesis; positive regulation of Ras protein signal transduction; and vulval cell fate specification. Located in nucleus. Expressed in several structures, including P3.pa; P3.pp; P4.pa; P5.ppp; and P7.paa. Is an ortholog of human SBNO1 (strawberry notch homolog 1). WB:WBGene00002890 let-766 No description available WB:WBGene00002891 let-767 Enables long-chain-fatty-acyl-CoA reductase activity and testosterone dehydrogenase [NAD(P)] activity. Involved in several processes, including female genitalia development; long-chain fatty acid biosynthetic process; and steroid metabolic process. Located in apical cortex and endoplasmic reticulum. Expressed in hypodermis; intestine; and pharynx. Used to study obesity. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). WB:WBGene00002892 let-768 No description available WB:WBGene00002893 let-769 No description available WB:WBGene00002894 let-771 No description available WB:WBGene00002895 let-774 No description available WB:WBGene00002896 let-775 No description available WB:WBGene00002897 let-776 No description available WB:WBGene00002898 let-777 No description available WB:WBGene00002899 let-778 No description available WB:WBGene00002900 let-780 No description available WB:WBGene00002901 let-782 No description available WB:WBGene00002902 let-783 No description available WB:WBGene00002903 let-784 No description available WB:WBGene00002904 let-786 No description available WB:WBGene00002905 let-789 No description available WB:WBGene00002906 let-791 No description available WB:WBGene00002907 let-792 No description available WB:WBGene00002908 let-793 No description available WB:WBGene00002909 let-794 No description available WB:WBGene00002910 let-795 No description available WB:WBGene00002911 let-796 No description available WB:WBGene00002912 let-797 No description available WB:WBGene00002913 let-798 No description available WB:WBGene00002914 let-799 No description available WB:WBGene00002915 let-805 Predicted to enable cytokine binding activity and cytokine receptor activity. Involved in hemidesmosome assembly. Located in hemidesmosome. Expressed in hypodermal cell; hypodermis; pharynx; touch receptor neurons; and uterine seam cell. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome and vesicoureteral reflux. Is an ortholog of human TNXB (tenascin XB). WB:WBGene00002916 let-809 No description available WB:WBGene00002917 let-810 No description available WB:WBGene00002918 let-811 No description available WB:WBGene00002919 let-812 No description available WB:WBGene00002920 let-813 No description available WB:WBGene00002921 let-814 No description available WB:WBGene00002922 let-815 No description available WB:WBGene00002923 let-816 No description available WB:WBGene00002924 let-817 No description available WB:WBGene00002925 let-818 No description available WB:WBGene00002926 let-819 No description available WB:WBGene00002927 let-820 No description available WB:WBGene00002928 let-821 No description available WB:WBGene00002929 let-822 No description available WB:WBGene00002930 let-823 No description available WB:WBGene00002931 let-824 No description available WB:WBGene00002932 let-825 No description available WB:WBGene00002933 let-826 No description available WB:WBGene00002934 let-827 No description available WB:WBGene00002935 let-828 No description available WB:WBGene00002936 let-829 No description available WB:WBGene00002937 let-830 No description available WB:WBGene00002938 let-831 No description available WB:WBGene00002939 let-832 No description available WB:WBGene00002940 let-834 No description available WB:WBGene00002941 let-835 No description available WB:WBGene00002942 let-836 No description available WB:WBGene00002943 let-837 No description available WB:WBGene00002944 let-838 No description available WB:WBGene00002945 let-839 No description available WB:WBGene00002946 let-840 No description available WB:WBGene00002947 let-841 No description available WB:WBGene00002948 let-842 No description available WB:WBGene00002949 let-843 No description available WB:WBGene00002950 let-844 No description available WB:WBGene00002951 let-852 No description available WB:WBGene00002952 let-853 No description available WB:WBGene00002953 let-854 No description available WB:WBGene00002954 let-855 No description available WB:WBGene00002955 let-856 No description available WB:WBGene00002956 let-857 No description available WB:WBGene00002957 let-858 Predicted to enable RNA binding activity. Involved in gastrulation and germ-line stem cell division. Located in germ cell nucleus and nucleoplasm. Part of chromatin. Expressed in somatic cell. Is an ortholog of human CWC22 (CWC22 spliceosome associated protein homolog). WB:WBGene00002958 let-908 No description available WB:WBGene00002959 let-972 No description available WB:WBGene00002960 let-974 No description available WB:WBGene00002961 let-975 No description available WB:WBGene00002962 let-976 No description available WB:WBGene00002963 let-977 No description available WB:WBGene00002964 let-978 No description available WB:WBGene00002965 let-979 No description available WB:WBGene00002966 let-980 No description available WB:WBGene00002967 let-981 No description available WB:WBGene00002968 let-982 No description available WB:WBGene00002969 let-983 No description available WB:WBGene00002970 let-984 No description available WB:WBGene00002971 let-985 No description available WB:WBGene00002972 let-986 No description available WB:WBGene00002973 let-987 No description available WB:WBGene00002974 lev-1 Enables acetylcholine receptor activity and acetylcholine-gated monoatomic cation-selective channel activity. Involved in regulation of egg-laying behavior; regulation of locomotion; and transmembrane transport. Located in neuron projection; neuronal cell body; and postsynaptic membrane. Expressed in body wall musculature; dorsal nerve cord; nerve ring; ventral cord neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including congenital myasthenic syndrome (multiple); lung disease (multiple); and nicotine dependence. Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit); and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). WB:WBGene00002975 lev-8 Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in several structures, including DD neuron; anal depressor muscle; ganglia; head neurons; and uterine-vulval cell. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 1A and congenital myasthenic syndrome 1B. Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit). WB:WBGene00002976 lev-9 Predicted to enable peptidase inhibitor activity. Located in extracellular space. Expressed in body wall musculature; cholinergic neurons; dorsal nerve cord; nerve ring; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; IgA glomerulonephritis; autoimmune disease (multiple); and coronary artery disease (multiple). Is an ortholog of several human genes including C4BPA (complement component 4 binding protein alpha); CR1 (complement C3b/C4b receptor 1 (Knops blood group)); and CR1L (complement C3b/C4b receptor 1 like). WB:WBGene00002977 lev-10 Located in membrane; synapse; and varicosity. WB:WBGene00002978 lev-11 Enables actin filament binding activity. Involved in several processes, including actin filament organization; regulation of actin polymerization or depolymerization; and spicule insertion. Located in striated muscle thin filament. Expressed in several structures, including body wall musculature; germ line; intestine; non-striated muscle; and pharynx. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); muscle tissue disease (multiple); and thyroid gland papillary carcinoma. Is an ortholog of several human genes including TPM1 (tropomyosin 1); TPM2 (tropomyosin 2); and TPM3 (tropomyosin 3). WB:WBGene00002979 lfe-2 Predicted to enable inositol tetrakisphosphate kinase activity and inositol-1,4,5-trisphosphate 3-kinase activity. Predicted to be involved in inositol phosphate biosynthetic process. Predicted to be located in cytoplasm and nucleus. Expressed in spermatheca. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human ITPKA (inositol-trisphosphate 3-kinase A); ITPKB (inositol-trisphosphate 3-kinase B); and ITPKC (inositol-trisphosphate 3-kinase C). WB:WBGene00002980 lgg-1 Predicted to enable GABA receptor binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including defense response to other organism; plasma membrane repair; and positive regulation of autophagosome assembly. Located in bounding membrane of organelle; neuron projection; and neuronal cell body. Expressed in several structures, including egg-laying apparatus; germ cell; hypodermis; intestine; and nervous system. Is an ortholog of human GABARAP (GABA type A receptor-associated protein). WB:WBGene00002981 lgg-2 Predicted to enable microtubule binding activity and ubiquitin protein ligase binding activity. Involved in cellular response to toxic substance; defense response to other organism; and positive regulation of autophagosome maturation. Acts upstream of or within with a positive effect on plasma membrane repair. Located in autophagosome membrane. Expressed in hypodermis; muscle cell; pharynx; spermatheca; and vulva. Human ortholog(s) of this gene implicated in glioblastoma; hypertrophic cardiomyopathy; and liver cirrhosis. Is an ortholog of human MAP1LC3A (microtubule associated protein 1 light chain 3 alpha); MAP1LC3B (microtubule associated protein 1 light chain 3 beta); and MAP1LC3B2 (microtubule associated protein 1 light chain 3 beta 2). WB:WBGene00002982 lgg-3 Involved in cellular response to toxic substance; determination of adult lifespan; and xenophagy. Acts upstream of or within with a positive effect on plasma membrane repair. Located in autophagosome membrane. Is an ortholog of human ATG12 (autophagy related 12). WB:WBGene00002983 lgx-1 Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds. Predicted to be involved in carbohydrate metabolic process. Expressed in somatic cell. WB:WBGene00002984 lgx-2 No description available WB:WBGene00002985 lig-1 Predicted to enable DNA ligase (ATP) activity. Predicted to be involved in DNA ligation and Okazaki fragment processing involved in mitotic DNA replication. Predicted to be located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in inherited metabolic disorder and primary immunodeficiency disease. Is an ortholog of human LIG1 (DNA ligase 1). WB:WBGene00002986 lig-4 Predicted to enable ATP binding activity; DNA binding activity; and DNA ligase (ATP) activity. Involved in DNA repair. Predicted to be located in nucleus. Predicted to be part of DNA ligase IV complex and DNA-dependent protein kinase-DNA ligase 4 complex. Expressed in head neurons; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including DNA ligase IV deficiency; multiple myeloma; and prostate cancer. Is an ortholog of human LIG4 (DNA ligase 4). WB:WBGene00002987 lim-4 Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell differentiation; positive regulation of transcription by RNA polymerase II; and serotonin biosynthetic process. Located in nucleus. Expressed in several structures, including ABalpppppa; head muscle; head neurons; lumbar neurons; and somatic nervous system. Is an ortholog of human LHX6 (LIM homeobox 6) and LHX8 (LIM homeobox 8). WB:WBGene00002988 lim-6 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including regulation of gene expression; system process; and uterus morphogenesis. Located in nucleus. Expressed in several structures, including amphid neurons; excretory system; hermaphrodite gonad; nerve ring neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 7 and nail-patella syndrome. Is an ortholog of human LMX1B (LIM homeobox transcription factor 1 beta). WB:WBGene00002989 lim-7 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including gonad morphogenesis; head morphogenesis; and pharynx development. Located in nucleus. Expressed in several structures, including body wall musculature; head neurons; lumbar neurons; pharyngeal neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including atrial fibrillation; diabetes mellitus (multiple); and heart septal defect (multiple). Is an ortholog of human ISL1 (ISL LIM homeobox 1) and ISL2 (ISL LIM homeobox 2). WB:WBGene00002990 lin-1 Enables sequence-specific DNA binding activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; negative regulation of transcription by RNA polymerase II; and vulval development. Located in nucleus. Part of RNA polymerase II transcription repressor complex. Expressed in vulval precursor cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Lewy body dementia; and schizophrenia. Is an ortholog of human ELK1 (ETS transcription factor ELK1). WB:WBGene00002991 lin-2 Enables insulin-like growth factor receptor binding activity. Involved in several processes, including egg-laying behavior; positive regulation of vulval development; and protein localization to membrane. Located in cell junction. Expressed in several structures, including CAN; HSN; isthmus; somatic nervous system; and vulval precursor cell. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in FG syndrome and syndromic X-linked intellectual disability Najm type. Is an ortholog of human CASK (calcium/calmodulin dependent serine protein kinase). WB:WBGene00002992 lin-3 Enables receptor ligand activity. Involved in several processes, including positive regulation of ovulation; positive regulation of vulval development; and reproductive process. Located in plasma membrane. Expressed in several structures, including excretory canal; germ line; hermaphrodite gonad; rectal epithelial cell; and vulF. WB:WBGene00002993 lin-4 Enables mRNA 3'-UTR binding activity. Involved in several processes, including egg-laying behavior; mating; and negative regulation of gene expression. Part of polysome. Expressed in several structures, including P5.p hermaphrodite; P7.p hermaphrodite; gonad; neurons; and ventral nerve cord. WB:WBGene00002994 lin-5 Enables dynein complex binding activity. Involved in several processes, including gonad development; microtubule cytoskeleton organization; and regulation of protein localization. Located in cell cortex; condensed chromosome; and spindle. WB:WBGene00002996 lin-7 Enables protein-macromolecule adaptor activity and signaling receptor binding activity. Involved in several processes, including egg-laying behavior; positive regulation of vulval development; and protein localization to basolateral plasma membrane. Located in cell-cell junction. Expressed in gonad; head; somatic gonad precursor; somatic nervous system; and vulval precursor cell. Is an ortholog of human LIN7A (lin-7 homolog A, crumbs cell polarity complex component); LIN7B (lin-7 homolog B, crumbs cell polarity complex component); and LIN7C (lin-7 homolog C, crumbs cell polarity complex component). WB:WBGene00002997 lin-8 Involved in negative regulation of vulval development. Located in nucleus. Expressed in germ line; head neurons; and oocyte. WB:WBGene00002998 lin-9 Predicted to enable DNA binding activity. Involved in embryo development; male sex differentiation; and regulation of multicellular organismal development. Part of DRM complex. Is an ortholog of human LIN9 (lin-9 DREAM MuvB core complex component). WB:WBGene00002999 lin-10 Enables small GTPase binding activity. Involved in several processes, including neuron-neuron synaptic transmission; positive regulation of backward locomotion; and protein localization. Located in several cellular components, including Golgi trans cisterna; somatodendritic compartment; and trans-Golgi network transport vesicle. Expressed in several structures, including ganglia; somatic gonad precursor; somatic nervous system; vulva; and vulval precursor cell. Is an ortholog of human APBA1 (amyloid beta precursor protein binding family A member 1) and APBA2 (amyloid beta precursor protein binding family A member 2). WB:WBGene00003000 lin-11 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including axonal fasciculation; egg-laying behavior; and positive regulation of vulval development. Predicted to be located in nucleus. Expressed in several structures, including head muscle; neurons; somatic nervous system; uterus; and vulva. Is an ortholog of human LHX1 (LIM homeobox 1). WB:WBGene00003001 lin-12 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including cell fate commitment; egg-laying behavior; and nematode larval development. Located in apical plasma membrane and nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including body wall muscle cell from M lineage; gonadal sheath cell; somatic nervous system; vulval cell; and vulval precursor cell. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); ductal carcinoma in situ; and hemangioblastoma. Is an ortholog of human NOTCH4 (notch receptor 4). WB:WBGene00003002 lin-13 Predicted to enable DNA binding activity and metal ion binding activity. Involved in negative regulation of vulval development and reproduction. Located in nucleus. Expressed in several structures, including body wall musculature; hermaphrodite distal tip cell; hypodermal cell; intestine; and neurons. WB:WBGene00003003 lin-14 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and single-stranded DNA binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; regulation of cell fate specification; and regulation of nematode larval development, heterochronic. Located in condensed nuclear chromosome. Expressed in several structures, including QL; QR; neurons; oocyte; and somatic nervous system. WB:WBGene00003004 lin-15 No description available WB:WBGene00003005 lin-16 No description available WB:WBGene00003006 lin-17 Enables receptor tyrosine kinase binding activity. Involved in several processes, including axis specification; cell differentiation; and sex differentiation. Located in neuron projection membrane. Expressed in several structures, including P3.p male; P4.p male; PQR; epithelial cell; and male-specific anatomical entity. WB:WBGene00003007 lin-18 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. Located in cytoplasm; nucleus; and plasma membrane. Expressed in body wall musculature; neurons; vulva; and vulval precursor cell. Is an ortholog of human RYK (receptor like tyrosine kinase). WB:WBGene00003008 lin-22 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in anterior/posterior pattern specification; negative regulation of gene expression; and nematode male tail tip morphogenesis. Acts upstream of or within epidermal cell fate specification. Predicted to be located in nucleus. Expressed in seam cell. Human ortholog(s) of this gene implicated in hemangiopericytoma. Is an ortholog of human HES1 (hes family bHLH transcription factor 1). WB:WBGene00003009 lin-23 Enables beta-catenin binding activity and phosphatase binding activity. Involved in several processes, including negative regulation of centrosome duplication; regulation of protein stability; and ubiquitin-dependent protein catabolic process. Located in cytosol and nucleus. Part of cytoplasmic SCF ubiquitin ligase complex. Expressed in several structures, including body wall musculature; enteric muscle; germ line; hypodermal cell; and neurons. Is an ortholog of human FBXW11 (F-box and WD repeat domain containing 11). WB:WBGene00003010 lin-24 Enriched in several structures, including germ line; head mesodermal cell; interfacial epithelial cell; neurons; and pharyngeal muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by five chemicals including Zidovudine; bortezomib; and paraquat based on RNA-seq and microarray studies. WB:WBGene00003011 lin-25 Involved in defense response to Gram-positive bacterium and vulval development. Acts upstream of or within with a positive effect on cell fate specification. Located in cytoplasm and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; hermaphrodite distal tip cell; and vulval cell. WB:WBGene00003012 lin-26 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; tissue development; and vulval development. Located in nucleus. Expressed in several structures, including Z2; epithelial cell; germ line; gonad; and somatic gonad precursor. WB:WBGene00003013 lin-27 No description available WB:WBGene00003014 lin-28 Enables RNA binding activity and enzyme binding activity. Involved in several processes, including regulation of cell fate specification; regulation of development, heterochronic; and regulation of gene expression. Located in cytoplasm and nucleus. Expressed in germ line; hypodermis; muscle cell; nervous system; and neurons. Is an ortholog of human LIN28A (lin-28 homolog A). WB:WBGene00003015 lin-29 Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including regulation of cellular component organization; regulation of gene expression; and regulation of nematode larval development. Located in nucleus. Expressed in several structures, including R2_hyp; gonad; hypodermis; neurons; and proctodeal cell. Is an ortholog of human ZNF362 (zinc finger protein 362). WB:WBGene00003016 lin-30 No description available WB:WBGene00003017 lin-31 Enables sequence-specific DNA binding activity. Involved in vulval development. Located in nucleus. Expressed in several structures, including P11.p; P9.p; gonad; nerve ring; and vulval precursor cell. Is an ortholog of human FOXB2 (forkhead box B2). WB:WBGene00003018 lin-32 Enables protein heterodimerization activity; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in several processes, including negative regulation of gliogenesis; nematode male tail tip morphogenesis; and neurogenesis. Located in nucleus. Expressed in several structures, including QL.a; QR.a; distal tip cell; oxygen sensory neurons; and ray precursor cell. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness. Is an ortholog of human ATOH1 (atonal bHLH transcription factor 1). WB:WBGene00003019 lin-33 Enriched in several structures, including ABalaaaarl; accessory cell; excretory cell; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-7; and gld-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including procyanidin; Sirolimus; and Rifampin based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00003020 lin-35 Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of cell cycle; negative regulation of vulval development; and positive regulation of brood size. Located in nucleus. Expressed in several structures, including head and tail. Used to study intellectual disability. Human ortholog(s) of this gene implicated in several diseases, including germ cell cancer (multiple); high grade glioma (multiple); and urinary system cancer (multiple). Is an ortholog of human RBL1 (RB transcriptional corepressor like 1) and RBL2 (RB transcriptional corepressor like 2). WB:WBGene00003021 lin-36 Predicted to enable DNA binding activity and metal ion binding activity. Involved in embryonic digestive tract morphogenesis. Predicted to be located in nucleus. Expressed in several structures, including P3.pa; P5.ppp; P7.paa; neurons; and vulval cell. WB:WBGene00003022 lin-37 Involved in embryonic digestive tract morphogenesis. Located in nucleus. Expressed widely. WB:WBGene00003024 lin-39 Enables cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of DNA-templated transcription; positive regulation of developmental process; and regulation of cell division. Located in nucleus. Expressed in several structures, including hypodermis; male-specific anatomical entity; neurons; somatic nervous system; and ventral cord blast cell. Is an ortholog of human HOXA5 (homeobox A5). WB:WBGene00003025 lin-40 Predicted to enable histone deacetylase binding activity; transcription coactivator activity; and transcription corepressor activity. Acts upstream of or within chromatin organization; mitochondrial unfolded protein response; and positive regulation of protein localization to nucleus. Located in nucleus. Part of NuRD complex. Expressed in distal tip cell and somatic cell. Is an ortholog of human MTA1 (metastasis associated 1) and MTA3 (metastasis associated 1 family member 3). WB:WBGene00003026 lin-41 Enables mRNA binding activity and translation repressor activity. Involved in several processes, including negative regulation of gene expression; regulation of developmental process; and reproductive process. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm. Part of messenger ribonucleoprotein complex. Expressed in several structures, including germ cell; hypodermal cell; intestine; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in hydrocephalus. Is an ortholog of human TRIM71 (tripartite motif containing 71). WB:WBGene00003028 lin-43 No description available WB:WBGene00003029 lin-44 Predicted to enable cytokine activity and frizzled binding activity. Involved in several processes, including nematode male tail tip morphogenesis; neuron migration; and positive regulation of cell projection organization. Predicted to be located in extracellular space. Expressed in several structures, including P6.pa; P6.pp; anchor cell; rectal epithelial cell; and tail. Human ortholog(s) of this gene implicated in several diseases, including Schopf-Schulz-Passarge syndrome; carcinoma (multiple); and split hand-foot malformation 6. Is an ortholog of several human genes including WNT10B (Wnt family member 10B); WNT11 (Wnt family member 11); and WNT9B (Wnt family member 9B). WB:WBGene00003030 lin-45 Enables small GTPase binding activity. Involved in several processes, including defense response to Gram-positive bacterium; intracellular signal transduction; and vulval development. Expressed in head neurons and vulval precursor cell. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome with multiple lentigines (multiple); carcinoma (multiple); and central nervous system benign neoplasm (multiple). Is an ortholog of human BRAF (B-Raf proto-oncogene, serine/threonine kinase). WB:WBGene00003031 lin-46 Predicted to enable molecular adaptor activity and molybdopterin molybdotransferase activity. Involved in regulation of development, heterochronic. Located in cytoplasm and nucleus. Expressed in hypodermis; seam cell; and vulval precursor cell. WB:WBGene00003032 lin-47 No description available WB:WBGene00003033 lin-48 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in anatomical structure morphogenesis and response to salt stress. Located in nucleus. Expressed in ciliated neurons; interfacial epithelial cell; intestine; labial sensillum; and tail. Human ortholog(s) of this gene implicated in posterior polymorphous corneal dystrophy 1. Is an ortholog of human OVOL1 (ovo like transcriptional repressor 1) and OVOL2 (ovo like zinc finger 2). WB:WBGene00003034 lin-49 Predicted to enable histone binding activity and nucleosome binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Is an ortholog of human BRPF1 (bromodomain and PHD finger containing 1) and BRPF3 (bromodomain and PHD finger containing 3). WB:WBGene00003035 lin-52 Involved in embryo development; negative regulation of signal transduction; and regulation of neurogenesis. Predicted to be located in nucleus. Predicted to be part of DRM complex. Expressed in AS neuron; anal depressor muscle; chemosensory neurons; excretory cell; and intestine. Is an ortholog of human LIN52 (lin-52 DREAM MuvB core complex component). WB:WBGene00003036 lin-53 Enables histone deacetylase binding activity. Involved in several processes, including cell fate specification; embryonic digestive tract morphogenesis; and nematode male tail tip morphogenesis. Acts upstream of or within mitochondrial unfolded protein response. Located in nucleus. Part of DRM complex and NuRD complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P7.p hermaphrodite; and P8.p hermaphrodite. Is an ortholog of human RBBP4 (RB binding protein 4, chromatin remodeling factor) and RBBP7 (RB binding protein 7, chromatin remodeling factor). WB:WBGene00003037 lin-54 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in autosome and condensed nuclear chromosome. Part of DRM complex. Expressed in several structures, including pharynx and vulva. Is an ortholog of human LIN54 (lin-54 DREAM MuvB core complex component) and TESMIN (testis expressed metallothionein like protein). WB:WBGene00003038 lin-56 Involved in several processes, including protein localization to nucleus; protein stabilization; and vulval development. Located in nucleus. Expressed in somatic cell. WB:WBGene00003039 mir-48 Involved in miRNA-mediated gene silencing by inhibition of translation and positive regulation of development, heterochronic. Expressed in P5.p hermaphrodite; P7.p hermaphrodite; RID; and seam cell. Used to study Parkinson's disease. WB:WBGene00003040 lin-59 Predicted to enable histone H3K36 methyltransferase activity. Involved in several processes, including ectodermal cell fate specification; egg-laying behavior; and nematode male tail tip morphogenesis. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed in hypodermis; intestine; and muscle cell. Used to study leukemia. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 52. Is an ortholog of human ASH1L (ASH1 like histone lysine methyltransferase). WB:WBGene00003041 lin-61 Predicted to enable chromatin binding activity and methylated histone binding activity. Involved in vulval development. Located in nucleus. Part of chromatin. Expressed widely. Is an ortholog of human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2) and MBTD1 (mbt domain containing 1). WB:WBGene00003042 lin-62 No description available WB:WBGene00003043 lip-1 Predicted to enable MAP kinase tyrosine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; and protein tyrosine/threonine phosphatase activity. Involved in several processes, including negative regulation of Ras protein signal transduction; positive regulation of vulval development; and vulval cell fate specification. Located in plasma membrane. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and germ line. Human ortholog(s) of this gene implicated in breast cancer and hypogonadotropic hypogonadism 19 with or without anosmia. Is an ortholog of human DUSP6 (dual specificity phosphatase 6) and DUSP7 (dual specificity phosphatase 7). WB:WBGene00003044 lir-1 Expressed in several structures, including head; intestinal cell; muscle cell; pharynx; and tail. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00003045 lir-2 Enriched in intestine; neurons; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including dpy-10; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; stavudine; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00003046 lir-3 Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Expressed in muscle cell; neurons; spermatheca; and vulva. WB:WBGene00003047 lis-1 Predicted to enable dynein complex binding activity and microtubule plus-end binding activity. Involved in several processes, including chiasma assembly; microtubule-based process; and organelle localization. Located in cell cortex; perinuclear region of cytoplasm; and supramolecular complex. Part of cytoplasmic dynein complex. Expressed in several structures, including hermaphrodite gonad; hypodermis; neurons; preanal ganglion; and somatic nervous system. Used to study lissencephaly. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lissencephaly 1; and schizophrenia. Is an ortholog of human PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1). WB:WBGene00003048 lit-1 Enables beta-catenin binding activity and protein serine/threonine kinase activity. Involved in several processes, including cell fate commitment; polarity specification of proximal/distal axis; and positive regulation of nematode male tail tip morphogenesis. Located in cell cortex and nucleus. Part of serine/threonine protein kinase complex. Expressed in several structures, including hermaphrodite gonad; pharynx; tail hypodermis; and vulva. Is an ortholog of human NLK (nemo like kinase). WB:WBGene00003049 liv-2 No description available WB:WBGene00003050 liv-4 No description available WB:WBGene00003051 liv-5 No description available WB:WBGene00003052 lmn-1 Enables histone binding activity; identical protein binding activity; and structural molecule activity. Involved in several processes, including cellular localization; determination of adult lifespan; and regulation of cell cycle. Located in nuclear envelope and nuclear periphery. Expressed in several structures, including ventral cord blast cell. Used to study Emery-Dreifuss muscular dystrophy; congenital muscular dystrophy; and progeria. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2B1; autosomal dominant Emery-Dreifuss muscular dystrophy 2; autosomal recessive Emery-Dreifuss muscular dystrophy 3; brain disease (multiple); congenital muscular dystrophy due to LMNA mutation; and intrinsic cardiomyopathy (multiple). Is an ortholog of human LMNA (lamin A/C). WB:WBGene00003053 lmp-1 Predicted to be involved in establishment of protein localization to organelle. Located in cytoplasmic vesicle and lysosomal membrane. Expressed in coelomocyte; germ line; and pharynx. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Is an ortholog of human LAMP2 (lysosomal associated membrane protein 2). WB:WBGene00003054 lmr-1 No description available WB:WBGene00003055 lon-1 Involved in several processes, including negative regulation of BMP signaling pathway; negative regulation of DNA endoreduplication; and positive regulation of growth rate. Located in adherens junction and plasma membrane. Expressed in head; hypodermis; intestinal cell; intestine; and tail. WB:WBGene00003056 lon-2 Enables growth factor binding activity. Involved in several processes, including negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; regulation of cell migration; and regulation of mesodermal cell fate specification. Located in cell surface. Expressed in hypodermis and intestine. WB:WBGene00003057 lon-3 Predicted to be a structural constituent of collagen and cuticulin-based cuticle. Involved in body morphogenesis and regulation of growth. Located in annuli extracellular matrix. Expressed in several structures, including H1L.apa; H1L.appa; H1L.p; cuticle; and hypodermal cell. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 5. Is an ortholog of human COLQ (collagen like tail subunit of asymmetric acetylcholinesterase). WB:WBGene00003058 lov-1 Enables protein domain specific binding activity. Involved in response to hermaphrodite contact and vulval location. Located in neuronal cell body and non-motile cilium. Expressed in CEM and in male. Used to study autosomal dominant polycystic kidney disease. WB:WBGene00003059 lpd-2 Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Expressed in nervous system. Is an ortholog of human NGDN (neuroguidin). WB:WBGene00003060 lpd-3 Predicted to be involved in synaptic vesicle endocytosis. Predicted to be located in membrane and presynapse. Expressed in intestine. Human ortholog(s) of this gene implicated in Alkuraya-Kucinskas syndrome. Is an ortholog of human BLTP1 (bridge-like lipid transfer protein family member 1). WB:WBGene00003061 lpd-5 Involved in lipid storage. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in Leigh disease and nuclear type mitochondrial complex I deficiency 1. Is an ortholog of human NDUFS4 (NADH:ubiquinone oxidoreductase subunit S4). WB:WBGene00003062 lpd-6 Predicted to enable rRNA binding activity. Involved in lipid storage. Predicted to be located in membrane. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human PPAN (peter pan homolog) and PPAN-P2RY11 (PPAN-P2RY11 readthrough). WB:WBGene00003063 lpd-7 Predicted to enable RNA binding activity. Involved in lipid storage. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of PeBoW complex. Is an ortholog of human PES1 (pescadillo ribosomal biogenesis factor 1). WB:WBGene00003064 nfu-1 Predicted to enable 4 iron, 4 sulfur cluster binding activity and iron ion binding activity. Involved in lipid storage. Predicted to be located in mitochondrion. Used to study multiple mitochondrial dysfunctions syndrome 1. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 1. Is an ortholog of human NFU1 (NFU1 iron-sulfur cluster scaffold). WB:WBGene00003065 lpd-9 Involved in lipid storage. Predicted to be located in membrane. WB:WBGene00003066 lpl-1 Predicted to enable lipoyl(octanoyl) transferase activity. Predicted to be involved in organic substance metabolic process and primary metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human LIPT2 (lipoyl(octanoyl) transferase 2). WB:WBGene00003067 lrg-1 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including nicotinic acid; Alovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00003068 lrk-1 Predicted to enable metal ion binding activity; protein kinase activity; and purine ribonucleoside triphosphate binding activity. Involved in several processes, including axon extension involved in axon guidance; cellular localization; and negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Located in Golgi apparatus and neuronal cell body. Expressed in hermaphrodite distal tip cell; neurons; pharynx; and vulva. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in osteosclerotic metaphyseal dysplasia. Is an ortholog of human LRRK1 (leucine rich repeat kinase 1). WB:WBGene00003069 lrn-1 Acts upstream of or within conditioned taste aversion. WB:WBGene00003070 lrn-2 Acts upstream of or within conditioned taste aversion. WB:WBGene00003071 lrp-1 Enables sterol transporter activity. Involved in several processes, including ecdysis, collagen and cuticulin-based cuticle; nematode larval development; and regulation of locomotion. Located in apical plasma membrane and endocytic vesicle. Expressed in head; hyp6; hyp7 syncytium; and hypodermal cell. Human ortholog(s) of this gene implicated in Donnai-Barrow syndrome and autoimmune thyroiditis. Is an ortholog of human LRP2 (LDL receptor related protein 2). WB:WBGene00003072 lrp-2 Involved in regulation of cell migration. Predicted to be located in plasma membrane. Expressed in tail. WB:WBGene00003073 lars-1 Predicted to enable leucine-tRNA ligase activity. Involved in positive regulation of protein phosphorylation and translation. Human ortholog(s) of this gene implicated in infantile liver failure syndrome 1. Is an ortholog of human LARS1 (leucyl-tRNA synthetase 1). WB:WBGene00003074 lars-2 Predicted to enable leucine-tRNA ligase activity. Predicted to be involved in leucyl-tRNA aminoacylation and mitochondrial translation. Predicted to be located in mitochondrion. Expressed in body wall musculature; intestine; and neurons. Used to study Perrault syndrome. Human ortholog(s) of this gene implicated in Perrault syndrome. Is an ortholog of human LARS2 (leucyl-tRNA synthetase 2, mitochondrial). WB:WBGene00003075 lrx-1 Enriched in mc3; pharynx; pm1; pm2; and pm7 based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including multi-walled carbon nanotube; D-glucose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: LDL receptor-like superfamily; Low-density lipoprotein receptor domain class A; and Low-density lipoprotein (LDL) receptor class A repeat. WB:WBGene00003076 lsm-1 Predicted to enable RNA cap binding activity. Predicted to be involved in deadenylation-dependent decapping of nuclear-transcribed mRNA. Located in P-body and cytoplasmic stress granule. Expressed in germ line and somatic cell. Is an ortholog of human LSM1 (LSM1 homolog, mRNA degradation associated). WB:WBGene00003077 lsm-3 Predicted to enable RNA binding activity. Predicted to be involved in P-body assembly and mRNA splicing, via spliceosome. Located in P-body. Is an ortholog of human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated). WB:WBGene00003078 lsm-4 Predicted to enable U6 snRNA binding activity. Predicted to be involved in P-body assembly and spliceosomal snRNP assembly. Located in cytoplasm and nucleus. Expressed in germ line and somatic cell. Human ortholog(s) of this gene implicated in atherosclerosis. Is an ortholog of human LSM4 (LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated). WB:WBGene00003079 lsm-5 Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Lsm1-7-Pat1 complex; U4/U6 x U5 tri-snRNP complex; and U6 snRNP. Is an ortholog of human LSM5 (LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated). WB:WBGene00003080 lsm-6 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome and maturation of SSU-rRNA. Predicted to be located in P-body and nucleolus. Predicted to be part of U4/U6 x U5 tri-snRNP complex; U6 snRNP; and sno(s)RNA-containing ribonucleoprotein complex. Expressed in body wall musculature; hermaphrodite somatic gonadal cell; and muscle cell. Is an ortholog of human LSM6 (LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated). WB:WBGene00003081 lsm-7 Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA processing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Lsm1-7-Pat1 complex and ribonucleoprotein complex. Is an ortholog of human LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated). WB:WBGene00003082 lsm-8 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex; U6 snRNP; and precatalytic spliceosome. Is an ortholog of human LSM8 (LSM8 homolog, U6 small nuclear RNA associated). WB:WBGene00003083 lst-1 Enables G-protein alpha-subunit binding activity. Involved in regulation of gene expression. Expressed in several structures, including accessory cell; amphid neurons; germ line; gonad; and oocyte. WB:WBGene00003084 lst-2 Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be located in early endosome membrane. Is an ortholog of human ZFYVE28 (zinc finger FYVE-type containing 28). WB:WBGene00003085 ccar-1 Predicted to enable hydrolase activity. Involved in hemidesmosome assembly. Predicted to be located in nucleus. Expressed widely. Is an ortholog of human CCAR1 (cell division cycle and apoptosis regulator 1). WB:WBGene00003086 lst-4 Enables enzyme binding activity; phosphatidylinositol phosphate binding activity; and protein self-association. Involved in execution phase of apoptosis and phagosome-lysosome fusion involved in apoptotic cell clearance. Located in early phagosome. Expressed in embryonic cell; gonad; and gonadal sheath cell. Is an ortholog of human SNX18 (sorting nexin 18) and SNX33 (sorting nexin 33). WB:WBGene00003087 lsy-2 Predicted to enable metal ion binding activity. Involved in nematode larval development; neuron fate specification; and positive regulation of gene expression. Located in nucleus. Expressed in several structures, including ASE; head muscle; head neurons; intestine; and somatic nervous system. WB:WBGene00003088 lsy-6 Enables mRNA 3'-UTR binding activity. Involved in determination of left/right asymmetry in nervous system and miRNA-mediated gene silencing. Expressed in ASEL; head neurons; and tail neurons. WB:WBGene00003089 ltd-1 Predicted to enable metal ion binding activity. Predicted to be involved in muscle structure development. Located in cell-cell junction and cytoplasm. Expressed in epithelial cell and isthmus. Human ortholog(s) of this gene implicated in myofibrillar myopathy 7. Is an ortholog of human KY (kyphoscoliosis peptidase). WB:WBGene00003090 lys-1 Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and innate immune response. Located in apical part of cell and cytoplasmic vesicle. Expressed in intestine and neurons. WB:WBGene00003091 lys-2 Predicted to enable lysozyme activity. Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and innate immune response. WB:WBGene00003092 lys-3 Involved in stress response to copper ion. WB:WBGene00003093 lys-4 Predicted to enable lysozyme activity. Involved in defense response to Gram-positive bacterium. WB:WBGene00003094 lys-5 Predicted to enable lysozyme activity. Involved in defense response to Gram-positive bacterium. WB:WBGene00003095 lys-6 Predicted to enable lysozyme activity. Predicted to be involved in innate immune response and signal transduction. WB:WBGene00003096 lys-7 Involved in defense response to other organism. Expressed in head neurons; intestine; and rectal gland cell. WB:WBGene00003097 lys-8 Involved in pharyngeal gland morphogenesis. Expressed in neurons and pharyngeal gland cell. WB:WBGene00003098 lys-9 Predicted to enable hydrolase activity. Predicted to be involved in innate immune response and signal transduction. WB:WBGene00003099 lys-10 Predicted to be involved in innate immune response and signal transduction. WB:WBGene00003100 mab-3 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of nematode male tail tip morphogenesis. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ADF; SMD; and in male. WB:WBGene00003101 mab-4 No description available WB:WBGene00003102 mab-5 Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including body ganglion; body wall musculature; male-specific anatomical entity; neurons; and vulval cell. Is an ortholog of human HOXB8 (homeobox B8) and HOXC8 (homeobox C8). WB:WBGene00003103 mab-6 No description available WB:WBGene00003104 mab-7 Predicted to be located in plasma membrane. Expressed in PQR; hypodermis; and vulva. WB:WBGene00003105 mab-8 No description available WB:WBGene00003106 mab-9 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and post-embryonic hindgut morphogenesis. Located in nucleus. Expressed in several structures, including B.a; B.p; neurons; proctodeum; and rectal epithelial cell. Human ortholog(s) of this gene implicated in atrial heart septal defect 4; tetralogy of Fallot; and ventricular septal defect. Is an ortholog of human TBX20 (T-box transcription factor 20). WB:WBGene00003107 mab-10 Enables DNA-binding transcription factor binding activity and transcription coregulator activity. Involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. Located in nucleus. Expressed in several structures, including gonad; hypodermis; pharynx; somatic nervous system; and vulval cell. Is an ortholog of human NAB1 (NGFI-A binding protein 1). WB:WBGene00003108 mab-12 No description available WB:WBGene00003109 mab-17 No description available WB:WBGene00003110 mab-19 No description available WB:WBGene00003111 mab-20 Enables semaphorin receptor binding activity. Involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. Located in cell surface. Expressed in several structures, including linker cell; ray neurons; ray precursor cell; somatic nervous system; and vulval cell. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Is an ortholog of human SEMA3B (semaphorin 3B) and SEMA3C (semaphorin 3C). WB:WBGene00003112 mab-21 Involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis. Expressed in several structures, including PVC; VA2; hyp7 syncytium; ray 6; and sensory neurons. Human ortholog(s) of this gene implicated in coloboma and syndromic microphthalmia 14. Is an ortholog of human MAB21L1 (mab-21 like 1) and MAB21L2 (mab-21 like 2). WB:WBGene00003114 mab-23 Predicted to enable metal ion binding activity and sequence-specific DNA binding activity. Involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process. Located in nucleus. Expressed in several structures, including U cell; hermaphrodite gonad; neurons; tail hypodermis; and ventral nerve cord. WB:WBGene00003115 mab-24 No description available WB:WBGene00003116 mab-25 No description available WB:WBGene00003117 mab-27 No description available WB:WBGene00003119 mac-1 Predicted to enable ATP hydrolysis activity and preribosome binding activity. Involved in lipid storage; negative regulation of apoptotic process; and positive regulation of nematode larval development. Predicted to be located in nucleus. Is an ortholog of human NVL (nuclear VCP like). WB:WBGene00003121 mad-2 No description available WB:WBGene00003122 mad-3 No description available WB:WBGene00003123 mag-1 Involved in feminization of hermaphroditic germ-line; nuclear mRNA surveillance; and positive regulation of reproductive process. Predicted to be located in nucleus. Predicted to be part of catalytic step 2 spliceosome and exon-exon junction complex. Is an ortholog of human MAGOH (mago homolog, exon junction complex subunit) and MAGOHB (mago homolog B, exon junction complex subunit). WB:WBGene00003124 mai-1 Enables ATPase inhibitor activity. Located in cytoplasm. Expressed in coelomocyte; cuticle; hypodermis; rectum; and vulva. Is an ortholog of human ATP5IF1 (ATP synthase inhibitory factor subunit 1). WB:WBGene00003128 mal-4 No description available WB:WBGene00003129 map-1 Predicted to enable metalloaminopeptidase activity. Predicted to be involved in protein modification process and proteolysis. Predicted to be located in cytosol. Is an ortholog of human METAP1 (methionyl aminopeptidase 1). WB:WBGene00003130 map-2 Enables exopeptidase activity. Acts upstream of or within with a positive effect on germ cell proliferation. Predicted to be located in cytoplasm. Is an ortholog of human METAP2 (methionyl aminopeptidase 2). WB:WBGene00003131 mar-1 No description available WB:WBGene00003132 mat-1 Involved in asymmetric cell division; cortical granule exocytosis; and polarity specification of anterior/posterior axis. Predicted to be located in cytoplasm. Predicted to be part of anaphase-promoting complex. Is an ortholog of human CDC27 (cell division cycle 27). WB:WBGene00003133 apc-1 Predicted to enable molecular adaptor activity. Involved in several processes, including establishment of meiotic spindle localization; metaphase/anaphase transition of cell cycle; and polarity specification of anterior/posterior axis. Part of anaphase-promoting complex. Human ortholog(s) of this gene implicated in Rothmund-Thomson syndrome. Is an ortholog of human ANAPC1 (anaphase promoting complex subunit 1). WB:WBGene00003134 mat-3 Predicted to enable molecular adaptor activity. Involved in asymmetric cell division; polarity specification of anterior/posterior axis; and positive regulation of metaphase/anaphase transition of meiosis I. Predicted to be part of anaphase-promoting complex. Is an ortholog of human CDC23 (cell division cycle 23). WB:WBGene00003135 mau-1 No description available WB:WBGene00003136 mau-2 Predicted to enable double-stranded DNA binding activity. Involved in anterior/posterior axon guidance; dorsal/ventral axon guidance; and egg-laying behavior. Located in axon and cytoplasm. Expressed in nervous system; oocyte; and vulval muscle. Is an ortholog of human MAU2 (MAU2 sister chromatid cohesion factor). WB:WBGene00003137 mau-3 No description available WB:WBGene00003138 mau-4 No description available WB:WBGene00003139 mau-5 No description available WB:WBGene00003140 mau-6 No description available WB:WBGene00003141 mau-7 No description available WB:WBGene00003142 mau-8 Expressed in body wall musculature; germ line; hypodermis; intestine; and pharynx. Is predicted to encode a protein with the following domains: Phosducin, thioredoxin-like domain; Phosducin, N-terminal domain superfamily; Phosducin; and Thioredoxin-like superfamily. Is an ortholog of human PDC (phosducin) and PDCL (phosducin like). WB:WBGene00003143 max-1 Involved in motor neuron axon guidance. Predicted to be located in cytoskeleton. Expressed in neurons. Is an ortholog of human PLEKHH1 (pleckstrin homology, MyTH4 and FERM domain containing H1) and PLEKHH2 (pleckstrin homology, MyTH4 and FERM domain containing H2). WB:WBGene00003144 max-2 Enables mitogen-activated protein kinase kinase kinase binding activity; protein serine/threonine kinase activity; and small GTPase binding activity. Involved in several processes, including gonad morphogenesis; inductive cell migration; and signal transduction. Predicted to be located in cytoplasm. Expressed in neurons; pharynx; and ventral nerve cord. WB:WBGene00003145 max-4 No description available WB:WBGene00003146 max-5 No description available WB:WBGene00003147 max-6 No description available WB:WBGene00003148 mbf-1 Predicted to enable DNA binding activity. Predicted to be located in nucleus. Expressed in tail. Is an ortholog of human EDF1 (endothelial differentiation related factor 1). WB:WBGene00003149 mbk-1 Predicted to enable protein serine/threonine kinase activity and transcription coactivator activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in several structures, including anterior gonad arm. Used to study Down syndrome and intellectual disability. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; abdominal obesity-metabolic syndrome 3; and autosomal dominant intellectual developmental disorder 7. Is an ortholog of human DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A). WB:WBGene00003150 mbk-2 Enables protein serine/threonine kinase activity and protein tyrosine kinase activity. Involved in several processes, including P granule disassembly; asymmetric protein localization involved in cell fate determination; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in cell cortex and intracellular non-membrane-bounded organelle. Expressed in several structures, including body wall musculature; embryonic cell; gonad; oocyte; and pharynx. Used to study Down syndrome. Is an ortholog of human DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) and DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3). WB:WBGene00003151 mca-1 Enables P-type calcium transporter activity and calmodulin binding activity. Involved in calcium ion transport and intracellular calcium ion homeostasis. Located in membrane. Expressed in excretory canal. WB:WBGene00003153 mca-3 Predicted to enable P-type calcium transporter activity. Involved in several processes, including negative regulation of cytosolic calcium ion concentration; positive regulation of endocytosis; and positive regulation of growth rate. Located in plasma membrane. Expressed in body wall musculature; coelomocyte; intestine; nervous system; and touch receptor neurons. Human ortholog(s) of this gene implicated in X-linked spinocerebellar ataxia 1; autosomal dominant intellectual developmental disorder; and nonsyndromic deafness (multiple). Is an ortholog of several human genes including ATP2B1 (ATPase plasma membrane Ca2+ transporting 1); ATP2B2 (ATPase plasma membrane Ca2+ transporting 2); and ATP2B3 (ATPase plasma membrane Ca2+ transporting 3). WB:WBGene00003154 mcm-2 Predicted to enable single-stranded DNA binding activity. Predicted to contribute to 3'-5' DNA helicase activity and single-stranded DNA helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication; double-strand break repair via break-induced replication; and mitotic DNA replication initiation. Located in condensed chromosome and pronucleus. Expressed in excretory cell; intestine; and uterus. Human ortholog(s) of this gene implicated in Alzheimer's disease and autosomal dominant nonsyndromic deafness 70. Is an ortholog of human MCM2 (minichromosome maintenance complex component 2). WB:WBGene00003155 mcm-3 Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Predicted to be involved in DNA strand elongation involved in DNA replication; double-strand break repair via break-induced replication; and mitotic DNA replication initiation. Located in condensed chromosome and pronucleus. Expressed in ciliated neurons. Is an ortholog of human MCM3 (minichromosome maintenance complex component 3). WB:WBGene00003156 mcm-4 Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Involved in gonad development; locomotion; and nervous system development. Located in nucleus. Expressed in several structures, including P lineage cell; Q lineage cell; Z2; somatic gonad precursor; and sperm. Human ortholog(s) of this gene implicated in immunodeficiency 54. Is an ortholog of human MCM4 (minichromosome maintenance complex component 4). WB:WBGene00003157 mcm-5 Predicted to enable single-stranded DNA binding activity. Predicted to contribute to 3'-5' DNA helicase activity and single-stranded DNA helicase activity. Predicted to be involved in DNA replication initiation and double-strand break repair via break-induced replication. Predicted to be located in nucleus. Predicted to be part of MCM complex. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 8. Is an ortholog of human MCM5 (minichromosome maintenance complex component 5). WB:WBGene00003158 mcm-6 Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded 3'-5' DNA helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication; double-strand break repair via break-induced replication; and mitotic DNA replication. Predicted to be located in nucleus. Predicted to be part of MCM complex. Is an ortholog of human MCM6 (minichromosome maintenance complex component 6). WB:WBGene00003159 mcm-7 Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Involved in MCM complex assembly; embryo development; and mitotic sister chromatid segregation. Predicted to be located in nucleus. Predicted to be part of MCM complex. Expressed in several structures, including anchor cell; intestine; tail; uterine epithelial cell; and vulval precursor cell. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and pancreatic ductal carcinoma. Is an ortholog of human MCM7 (minichromosome maintenance complex component 7). WB:WBGene00003160 mdf-1 Enables protein kinase binding activity. Involved in embryo development; mitotic spindle assembly; and regulation of mitotic sister chromatid separation. Located in kinetochore; nuclear membrane; and nuclear periphery. Expressed in Z1; Z2; Z3; Z4; and intestine. Human ortholog(s) of this gene implicated in lymphoma; mosaic variegated aneuploidy syndrome; and prostate cancer. Is an ortholog of human MAD1L1 (mitotic arrest deficient 1 like 1). WB:WBGene00003161 mdf-2 Involved in embryo development; mitotic spindle assembly checkpoint signaling; and response to anoxia. Located in kinetochore; microtubule cytoskeleton; and nucleus. Expressed in germ line. Is an ortholog of human MAD2L1 (mitotic arrest deficient 2 like 1). WB:WBGene00003162 mdh-2 Enables L-malate dehydrogenase activity. Involved in malate metabolic process. Located in mitochondrion. Used to study hyperglycemia. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 51. Is an ortholog of human MDH2 (malate dehydrogenase 2). WB:WBGene00003163 mdl-1 Enables protein heterodimerization activity. Contributes to sequence-specific DNA binding activity. Involved in determination of adult lifespan and regulation of cell differentiation. Located in nucleus. Part of transcription regulator complex. Expressed in body wall musculature; neurons; pharynx; and somatic nervous system. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in neurofibrosarcoma and prostate cancer. Is an ortholog of human MXI1 (MAX interactor 1, dimerization protein). WB:WBGene00003164 mdt-6 Predicted to enable transcription coactivator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is an ortholog of human MED6 (mediator complex subunit 6). WB:WBGene00003165 mec-1 Predicted to enable serine-type endopeptidase inhibitor activity. Involved in detection of mechanical stimulus involved in sensory perception of touch; extracellular structure organization; and mechanosensory behavior. Predicted to be located in extracellular space. Expressed in PVT; cholinergic neurons; intestinal muscle; and touch receptor neurons. WB:WBGene00003166 mec-2 Enables cholesterol binding activity. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. Located in neuron projection membrane. Expressed in sensory neurons. Used to study nephrotic syndrome. Is an ortholog of human STOM (stomatin). WB:WBGene00003167 mec-3 Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including mechanosensory behavior; neuron projection organization; and positive regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. Expressed in VA neuron; touch receptor neurons; ventral nerve cord; and vulva. Is an ortholog of human LHX1 (LIM homeobox 1) and LHX5 (LIM homeobox 5). WB:WBGene00003168 mec-4 Enables ligand-gated sodium channel activity. Involved in regulation of multicellular organismal process; response to mechanical stimulus; and sodium ion transmembrane transport. Located in axon and neuron projection membrane. Expressed in touch receptor neurons. Used to study ischemia and neurodegenerative disease. Human ortholog(s) of this gene implicated in bronchiectasis (multiple); neuroblastoma; and renal tubular transport disease (multiple). Is an ortholog of human SCNN1B (sodium channel epithelial 1 subunit beta); SCNN1D (sodium channel epithelial 1 subunit delta); and SCNN1G (sodium channel epithelial 1 subunit gamma). WB:WBGene00003169 mec-5 Predicted to be an extracellular matrix structural constituent. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. Located in extracellular matrix. Expressed in head; hypodermis; muscle cell; tail; and touch receptor neurons. WB:WBGene00003170 mec-6 Predicted to enable arylesterase activity and sodium channel activity. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. Predicted to be located in axon and plasma membrane. Expressed in several structures, including enteric muscle; excretory cell; mechanosensory neurons; nerve ring; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); eye disease (multiple); and hematologic cancer (multiple). Is an ortholog of human PON1 (paraoxonase 1). WB:WBGene00003171 mec-7 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in cytoplasmic microtubule organization; positive regulation of multicellular organismal process; and response to mechanical stimulus. Located in neuron projection and neuronal cell body. Expressed in BDU and mechanosensory neurons. Used to study hypokalemic periodic paralysis. Human ortholog(s) of this gene implicated in Leber congenital amaurosis with early-onset deafness; brain disease (multiple); and congenital symmetric circumferential skin creases 1. Is an ortholog of human TUBB (tubulin beta class I); TUBB4A (tubulin beta 4A class IVa); and TUBB4B (tubulin beta 4B class IVb). WB:WBGene00003172 mec-8 Predicted to enable mRNA binding activity. Involved in several processes, including hemidesmosome assembly; mechanosensory behavior; and nematode larval development. Located in nucleus. Expressed in several structures, including head muscle; hypodermis; and vulva. Is an ortholog of human RBPMS (RNA binding protein, mRNA processing factor) and RBPMS2 (RNA binding protein, mRNA processing factor 2). WB:WBGene00003173 mec-9 Predicted to enable calcium ion binding activity and serine-type endopeptidase inhibitor activity. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. Predicted to be located in extracellular region. Expressed in PVDL; PVDR; head neurons; touch receptor neurons; and ventral cord neurons. WB:WBGene00003174 mec-10 Enables ligand-gated sodium channel activity. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. Located in cell body membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in bronchiectasis (multiple); neuroblastoma; and renal tubular transport disease (multiple). Is an ortholog of human SCNN1B (sodium channel epithelial 1 subunit beta); SCNN1D (sodium channel epithelial 1 subunit delta); and SCNN1G (sodium channel epithelial 1 subunit gamma). WB:WBGene00003175 mec-12 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in several processes, including positive regulation of multicellular organismal process; response to mechanical stimulus; and thigmotaxis. Located in axon; microtubule; and neuronal cell body. Expressed in nerve ring and neurons. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; amyotrophic lateral sclerosis type 22; and lissencephaly 3. Is an ortholog of human TUBA3C (tubulin alpha 3c) and TUBA3D (tubulin alpha 3d). WB:WBGene00003176 mec-14 Predicted to enable oxidoreductase activity. Involved in positive regulation of multicellular organismal process and response to mechanical stimulus. WB:WBGene00003177 mec-15 Involved in several processes, including positive regulation of GABAergic synaptic transmission; positive regulation of multicellular organismal process; and response to mechanical stimulus. Located in perikaryon. Expressed in neurons and spermatheca. Is an ortholog of human FBXW9 (F-box and WD repeat domain containing 9). WB:WBGene00003178 mec-17 Enables tubulin N-acetyltransferase activity. Involved in mechanoreceptor differentiation and thigmotaxis. Predicted to be located in microtubule. Expressed in touch receptor neurons. Used to study neurodegenerative disease. Is an ortholog of human ATAT1 (alpha tubulin acetyltransferase 1). WB:WBGene00003179 mec-18 Predicted to enable CoA-ligase activity. Involved in detection of mechanical stimulus involved in sensory perception of touch and mechanosensory behavior. Located in neuron projection and neuronal cell body. Expressed in PLML; PLMR; and touch receptor neurons. WB:WBGene00003180 med-1 Enables sequence-specific DNA binding activity. Involved in endodermal cell fate specification and pharynx development. Located in nucleus. Expressed in several structures, including MSaaaap; MSaapap; MSappp; MSppapa; and MSppapp. WB:WBGene00003181 med-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate specification and pharynx development. Predicted to be located in nucleus. Expressed in E; EMS; MS; and gonad. WB:WBGene00003182 mef-2 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and histone deacetylase binding activity. Involved in several processes, including receptor guanylyl cyclase signaling pathway; regulation of acetylcholine secretion, neurotransmission; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including hypodermis. Used to study autism spectrum disorder and intellectual disability. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; lung cancer; and neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language. Is an ortholog of human MEF2A (myocyte enhancer factor 2A); MEF2C (myocyte enhancer factor 2C); and MEF2D (myocyte enhancer factor 2D). WB:WBGene00003183 mei-1 Enables several functions, including ATP binding activity; MATH domain binding activity; and microtubule severing ATPase activity. Involved in several processes, including cytoskeleton organization; female meiotic nuclear division; and negative regulation of meiotic spindle elongation. Located in meiotic spindle pole and nucleus. Part of chromatin and katanin complex. Expressed in ciliated neurons; germ line; and head neurons. Is an ortholog of human KATNA1 (katanin catalytic subunit A1) and KATNAL1 (katanin catalytic subunit A1 like 1). WB:WBGene00003184 mei-2 Contributes to microtubule severing ATPase activity. Involved in embryo development; meiotic spindle organization; and microtubule depolymerization. Located in cytoplasm; nucleus; and spindle pole. Part of katanin complex. WB:WBGene00003185 mek-1 Enables JUN kinase kinase activity and SH2 domain binding activity. Involved in several processes, including gamete generation; response to metal ion; and stress-activated MAPK cascade. Predicted to be located in cytoplasm. Expressed in several structures, including ganglia; hermaphrodite gonad; intestine; nerve ring; and pharynx. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lung adenocarcinoma; and prostate carcinoma in situ. Is an ortholog of human MAP2K7 (mitogen-activated protein kinase kinase 7). WB:WBGene00003186 mek-2 Enables protein serine/threonine/tyrosine kinase activity and scaffold protein binding activity. Involved in defense response to Gram-positive bacterium; intracellular signal transduction; and vulval development. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); cardiofaciocutaneous syndrome 3; and cardiofaciocutaneous syndrome 4. Is an ortholog of human MAP2K1 (mitogen-activated protein kinase kinase 1) and MAP2K2 (mitogen-activated protein kinase kinase 2). WB:WBGene00003187 mel-1 Acts upstream of or within embryo development. WB:WBGene00003189 mel-3 Acts upstream of or within embryo development. WB:WBGene00003190 mel-4 Acts upstream of or within embryo development. WB:WBGene00003191 mel-5 Acts upstream of or within embryo development. WB:WBGene00003192 mel-7 Acts upstream of or within embryo development. WB:WBGene00003193 mel-8 Acts upstream of or within embryo development. WB:WBGene00003194 mel-9 Acts upstream of or within embryo development. WB:WBGene00003195 mel-10 Acts upstream of or within embryo development. WB:WBGene00003196 mel-11 Predicted to enable enzyme inhibitor activity and phosphatase regulator activity. Involved in embryo development and embryonic body morphogenesis. Located in adherens junction and cytoplasm. Expressed in Z2; Z3; hyp7 syncytium; intestine; and pharynx. Is an ortholog of human PPP1R12B (protein phosphatase 1 regulatory subunit 12B). WB:WBGene00003197 mel-12 Acts upstream of or within embryo development. WB:WBGene00003198 mel-13 Acts upstream of or within embryo development. WB:WBGene00003199 mel-14 Acts upstream of or within embryo development. WB:WBGene00003201 mel-16 Acts upstream of or within embryo development. WB:WBGene00003202 mel-17 Acts upstream of or within embryo development. WB:WBGene00003203 mel-18 Acts upstream of or within embryo development. WB:WBGene00003204 mel-20 Acts upstream of or within embryo development. WB:WBGene00003205 mel-22 Acts upstream of or within embryo development. WB:WBGene00003206 mel-23 No description available WB:WBGene00003207 mel-24 No description available WB:WBGene00003208 mel-25 No description available WB:WBGene00003209 mel-26 Enables several functions, including cullin family protein binding activity; identical protein binding activity; and protein kinase binding activity. Involved in several processes, including cytoskeleton organization; positive regulation of TORC1 signaling; and protein metabolic process. Located in several cellular components, including cleavage furrow; condensed chromosome; and sarcomere. Expressed in germ line and muscle cell. WB:WBGene00003210 mel-28 Enables molecular adaptor activity. Involved in mitotic sister chromatid segregation and nuclear pore complex assembly. Located in kinetochore; nuclear envelope; and nucleoplasm. Part of nuclear pore. WB:WBGene00003211 mel-29 No description available WB:WBGene00003212 mel-30 No description available WB:WBGene00003213 mel-31 No description available WB:WBGene00003214 mel-32 Predicted to enable several functions, including glycine hydroxymethyltransferase activity; ion binding activity; and nucleic acid binding activity. Involved in embryo development. Located in mitochondrion. Human ortholog(s) of this gene implicated in breast cancer and ovarian cancer. Is an ortholog of human SHMT1 (serine hydroxymethyltransferase 1). WB:WBGene00003215 mel-33 No description available WB:WBGene00003216 memi-1 Enriched in AFD; Y cell; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00003217 mel-44 No description available WB:WBGene00003218 mep-1 Enables RNA binding activity; enzyme binding activity; and identical protein binding activity. Involved in developmental process involved in reproduction; positive regulation of gene expression; and vulval development. Located in nucleus. Expressed in anchor cell; embryonic cell; excretory cell; germ line; and somatic nervous system. WB:WBGene00003219 mes-1 Predicted to enable protein tyrosine kinase activity. Involved in several processes, including cell fate commitment; establishment of mitotic spindle localization; and left/right axis specification. Located in plasma membrane. Expressed in E; Psub2; Psub3; and Psub4. WB:WBGene00003220 mes-2 Enables histone H3K27 methyltransferase activity. Involved in epigenetic regulation of gene expression; germ-line stem cell division; and tissue development. Part of PcG protein complex and nucleosome. Expressed in Z2; Z3; germ line; hypodermis; and intestine. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human EZH1 (enhancer of zeste 1 polycomb repressive complex 2 subunit) and EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit). WB:WBGene00003221 mes-3 Involved in regulation of gene expression. Located in nucleus. Part of PcG protein complex and nucleosome. Expressed in several structures, including Caa; Psub4; Z2; Z3; and germ line. WB:WBGene00003222 mes-4 Enables histone H3K36 methyltransferase activity. Involved in germ-line sex determination and heterochromatin formation. Acts upstream of or within with a positive effect on inactivation of X chromosome by heterochromatin formation. Located in X chromosome; autosome; and nuclear chromosome. Part of chromatin. Expressed in Z2; Z3; and germ line. Human ortholog(s) of this gene implicated in several diseases, including Sotos syndrome 1; lung non-small cell carcinoma; and neuroblastoma. Is an ortholog of human NSD1 (nuclear receptor binding SET domain protein 1); NSD2 (nuclear receptor binding SET domain protein 2); and NSD3 (nuclear receptor binding SET domain protein 3). WB:WBGene00003223 mes-5 No description available WB:WBGene00003224 mes-6 Predicted to contribute to nucleosome binding activity. Involved in regulation of gene expression. Part of PcG protein complex and nucleosome. Expressed in Z2; Z3; germ line; intestinal cell; and oocyte. Is an ortholog of human EED (embryonic ectoderm development). WB:WBGene00003225 mev-1 Predicted to enable heme binding activity. Involved in several processes, including defense response to other organism; determination of adult lifespan; and regulation of response to oxidative stress. Located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including Carney-Stratakis syndrome; gastrointestinal stromal tumor; and paraganglioma. Is an ortholog of human SDHC (succinate dehydrogenase complex subunit C). WB:WBGene00003226 mev-2 No description available WB:WBGene00003227 mev-3 No description available WB:WBGene00003228 mex-1 Predicted to enable mRNA 3'-UTR binding activity. Involved in several processes, including embryonic pattern specification; establishment of cell polarity; and formation of primary germ layer. Located in P granule. Expressed in germ line. WB:WBGene00003229 mex-3 Enables single-stranded RNA binding activity. Involved in several processes, including negative regulation of muscle cell differentiation; organelle inheritance; and regulation of gene expression. Located in P granule. Expressed in distal tip cell and embryonic cell. Is an ortholog of human MEX3A (mex-3 RNA binding family member A) and MEX3B (mex-3 RNA binding family member B). WB:WBGene00003230 mex-5 Enables RNA binding activity; protein domain specific binding activity; and protein kinase binding activity. Involved in regulation of protein localization. Located in P granule and centrosome. Expressed in germ line; head muscle; head neurons; intestine; and somatic nervous system. WB:WBGene00003231 mex-6 Enables mRNA 3'-UTR binding activity; protein domain specific binding activity; and protein kinase binding activity. Involved in regulation of protein localization. Located in P granule. Expressed in AB; ABa; ABp; and germ line. WB:WBGene00003232 mgl-1 Predicted to enable group II metabotropic glutamate receptor activity. Involved in positive regulation of lipid storage. Predicted to be located in plasma membrane. Expressed in nerve ring; neurons; and pharyngeal nervous system. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; autistic disorder; and congenital stationary night blindness 1B. Is an ortholog of human GRM3 (glutamate metabotropic receptor 3). WB:WBGene00003233 mgl-2 Predicted to enable G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential; adenylate cyclase inhibiting G protein-coupled glutamate receptor activity; and neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to be located in postsynaptic density membrane. Expressed in several structures, including glutamatergic neurons; head neurons; pharyngeal nervous system; somatic nervous system; and tail neurons. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 13 and spinocerebellar ataxia 44. Is an ortholog of human GRM1 (glutamate metabotropic receptor 1). WB:WBGene00003234 mif-1 Predicted to enable cytokine activity and phenylpyruvate tautomerase activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cystic fibrosis; and lung disease (multiple). Is an ortholog of human MIF (macrophage migration inhibitory factor). WB:WBGene00003235 mif-2 Predicted to enable cytokine activity and phenylpyruvate tautomerase activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular space. Expressed in body wall musculature; hypodermis; and vulval muscle. Is an ortholog of human DDT (D-dopachrome tautomerase) and DDTL (D-dopachrome tautomerase like). WB:WBGene00003236 mif-3 Predicted to enable cytokine activity and phenylpyruvate tautomerase activity. Involved in regulation of lipid storage and regulation of peptide transport. Located in nucleus. Expressed in body wall musculature; pharyngeal muscle cell; and vulval muscle. WB:WBGene00003237 mif-4 Predicted to enable cytokine activity and phenylpyruvate tautomerase activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular space. WB:WBGene00003238 mig-1 Predicted to enable Wnt receptor activity and Wnt-protein binding activity. Involved in several processes, including mitochondrial unfolded protein response; neuron migration; and positive regulation of axon guidance. Predicted to be located in plasma membrane. Expressed in anal depressor muscle; head muscle; and neurons. Human ortholog(s) of this gene implicated in exudative vitreoretinopathy 1 and prostate carcinoma in situ. Is an ortholog of human FZD4 (frizzled class receptor 4). WB:WBGene00003239 mig-2 Enables GTPase activity and protein kinase binding activity. Involved in several processes, including actin cytoskeleton organization; axon guidance; and cell migration. Located in cytoplasm; cytoplasmic side of plasma membrane; and neuron projection. Expressed in several structures, including CAN; HSN; distal tip cell; touch receptor neurons; and vulval cell. Used to study epilepsy. Is an ortholog of human RHOG (ras homolog family member G). WB:WBGene00003240 mig-4 No description available WB:WBGene00003241 mig-5 Predicted to enable frizzled binding activity. Involved in several processes, including cell differentiation; inductive cell migration; and non-canonical Wnt signaling pathway. Located in cell cortex. Expressed in several structures, including distal tip cell; linker cell; nerve ring; posterior lateral left ganglion; and somatic gonad precursor. Human ortholog(s) of this gene implicated in DiGeorge syndrome; Robinow syndrome (multiple); and lung cancer. Is an ortholog of human DVL1 (dishevelled segment polarity protein 1); DVL2 (dishevelled segment polarity protein 2); and DVL3 (dishevelled segment polarity protein 3). WB:WBGene00003242 mig-6 Predicted to enable serine-type endopeptidase inhibitor activity. Involved in several processes, including anatomical structure morphogenesis; distal tip cell migration; and nematode larval development. Located in basement membrane. Expressed in several structures, including CAN; GLR; basal lamina; enteric muscle; and somatic gonad precursor. Is an ortholog of human PAPLN (papilin, proteoglycan like sulfated glycoprotein). WB:WBGene00003243 mig-10 Enables SH3 domain binding activity. Involved in several processes, including cell migration; cell projection organization; and egg-laying behavior. Located in neuronal cell body membrane; plasma membrane bounded cell projection; and presynaptic cytosol. Part of filamentous actin. Expressed in hermaphrodite gonad; neurons; and tail. Is an ortholog of human RAPH1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1). WB:WBGene00003244 mig-12 No description available WB:WBGene00003245 mig-13 Involved in positive regulation of cell migration. Located in axon; neuronal cell body; and plasma membrane. Expressed in several structures, including QR.a; QR.p; QR.pa; body ganglion; and somatic neurons. WB:WBGene00003246 mig-14 Predicted to enable Wnt-protein binding activity. Involved in several processes, including Wnt signaling pathway; embryonic morphogenesis; and left/right axis specification. Located in basolateral plasma membrane and cytoplasmic vesicle. Expressed in several structures, including CAN; anal region; intestinal muscle; tail hypodermis; and ventral nerve cord. Is an ortholog of human WLS (Wnt ligand secretion mediator). WB:WBGene00003247 mig-15 Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including body morphogenesis; dorsal/ventral axon guidance; and regulation of GABAergic synaptic transmission. Predicted to be located in cytoplasm. Expressed in several structures, including QL; QR; body wall musculature; pharynx; and somatic nervous system. Used to study epilepsy. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive intellectual developmental disorder 54; gastrointestinal system cancer (multiple); and hepatitis B. Is an ortholog of human MAP4K4 (mitogen-activated protein kinase kinase kinase kinase 4); MINK1 (misshapen like kinase 1); and TNIK (TRAF2 and NCK interacting kinase). WB:WBGene00003248 mig-17 Enables metallopeptidase activity. Involved in several processes, including gonad morphogenesis; protein processing; and regulation of distal tip cell migration. Located in basement membrane and extracellular space. Expressed in several structures, including body wall musculature; gonad; head; intestine; and ventral nerve cord. WB:WBGene00003249 mig-18 Predicted to be located in basement membrane and extracellular region. Expressed in body wall musculature; gonad; and pharyngeal muscle cell. WB:WBGene00003250 mig-19 No description available WB:WBGene00003251 mig-20 No description available WB:WBGene00003252 mig-21 Predicted to enable signaling receptor activity. Involved in several processes, including cell migration; determination of left/right asymmetry in nervous system; and regulation of canonical Wnt signaling pathway. Predicted to be located in plasma membrane. Expressed in QL; QR; and body wall musculature. WB:WBGene00003253 mig-22 Enables enzyme binding activity. Predicted to be involved in chondroitin sulfate biosynthetic process. Predicted to be located in Golgi cisterna membrane. Expressed in anterior distal tip cell; oocyte; posterior distal tip cell; and vulva. Is an ortholog of human CHPF (chondroitin polymerizing factor) and CHPF2 (chondroitin polymerizing factor 2). WB:WBGene00003254 mig-23 Enables ADP phosphatase activity; GDP phosphatase activity; and UDP phosphatase activity. Involved in several processes, including gonad morphogenesis; positive regulation of protein glycosylation; and ribonucleoside diphosphate catabolic process. Located in cytoplasm. Expressed in head and tail. Is an ortholog of human ENTPD4 (ectonucleoside triphosphate diphosphohydrolase 4) and ENTPD7 (ectonucleoside triphosphate diphosphohydrolase 7). WB:WBGene00003256 mig-25 No description available WB:WBGene00003257 mig-26 No description available WB:WBGene00003258 cogc-1 Involved in several processes, including gonad morphogenesis; regulation of cell migration; and vulval development. Predicted to be located in Golgi apparatus. Predicted to be part of Golgi transport complex. Expressed in germ line. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIg. Is an ortholog of human COG1 (component of oligomeric golgi complex 1). WB:WBGene00003259 mio-1 No description available WB:WBGene00003260 mir-1 Expressed in body wall musculature; muscle cell; and pharyngeal muscle cell. Used to study Parkinson's disease. WB:WBGene00003261 mir-2 Predicted to enable mRNA base-pairing translational repressor activity. Predicted to be involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be part of RISC complex. Expressed in neurons. WB:WBGene00003262 mir-34 Involved in several processes, including determination of adult lifespan; negative regulation of autophagy; and response to heat. Expressed in excretory canal; hypodermis; neurons; somatic nervous system; and vulval precursor cell. WB:WBGene00003263 mir-35 Predicted to enable mRNA binding activity. Predicted to be involved in RNA destabilization. Expressed in germ line. WB:WBGene00003264 mir-36 Predicted to enable mRNA binding activity. Predicted to be involved in RNA destabilization. Expressed in germ line. WB:WBGene00003265 mir-37 Predicted to enable mRNA binding activity. Predicted to be involved in RNA destabilization. Expressed in germ line. WB:WBGene00003266 mir-38 Expressed in germ line. WB:WBGene00003267 mir-39 Expressed in germ line. WB:WBGene00003268 mir-40 Expressed in germ line. WB:WBGene00003269 mir-41 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by four chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and nicotine based on RNA-seq studies. WB:WBGene00003270 mir-42 Expressed in seam cell. WB:WBGene00003271 mir-43 Expressed in germ line and seam cell. WB:WBGene00003272 mir-44 Expressed in seam cell. WB:WBGene00003273 mir-45 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00003274 mir-46 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. WB:WBGene00003275 mir-47 Is affected by several genes including hsf-1; eat-2; and prg-1 based on RNA-seq studies. Is affected by four chemicals including nicotine; multi-walled carbon nanotube; and Microcystin-LR based on quantitative PCR; RNA-seq; and microarray studies. WB:WBGene00003277 mir-49 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR studies. WB:WBGene00003278 mir-50 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Used to study Parkinson's disease. WB:WBGene00003279 mir-51 Expressed in arcade cell and tail hypodermis. WB:WBGene00003280 mir-52 Expressed in several structures, including arcade cell; coelomocyte; gonad; hypodermis; and vulva. WB:WBGene00003281 mir-53 Expressed in arcade cell; distal tip cell; hypodermis; muscle cell; and neurons. WB:WBGene00003282 mir-54 Expressed in several structures, including excretory system; hypodermis; neurons; and seam cell. WB:WBGene00003283 mir-55 Expressed in several structures, including excretory system; hypodermis; neurons; and seam cell. WB:WBGene00003284 mir-56 Predicted to be involved in RNA destabilization. Expressed in several structures, including excretory system; hypodermis; neurons; and seam cell. WB:WBGene00003285 mir-57 Expressed in several structures, including P11; P12; body wall musculature; hypodermis; and tail spike. WB:WBGene00003286 mir-58.1 Expressed in several structures, including excretory cell; hypodermis; intestine; pharynx; and spermatheca. WB:WBGene00003287 mir-59 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. WB:WBGene00003288 mir-60 Is affected by several genes including daf-12; eat-2; and glp-4 based on tiling array and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00003289 mir-61 Involved in miRNA-mediated gene silencing and regulation of vulval development. Expressed in several structures, including P5.p hermaphrodite; P5.pa; P5.pp; P7.p hermaphrodite; and P7.pa. WB:WBGene00003290 mir-62 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. WB:WBGene00003291 mir-63 Expressed in neurons. WB:WBGene00003292 mir-64 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. Used to study Parkinson's disease. WB:WBGene00003293 mir-65 Is affected by several genes including eat-2; glp-4; and prg-1 based on RNA-seq studies. Used to study Parkinson's disease. WB:WBGene00003294 mir-66 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by nicotine based on RNA-seq studies. WB:WBGene00003295 mir-67 Expressed in body wall musculature; intestinal muscle; and vulval muscle. WB:WBGene00003296 Y51H4A.27 No description available WB:WBGene00003297 Y41D4B.25 Is affected by daf-12 based on tiling array studies. WB:WBGene00003298 mir-70 Is affected by several genes including eat-2; glp-4; and prg-1 based on RNA-seq studies. Is affected by methylmercury hydroxide based on RNA-seq studies. WB:WBGene00003299 mir-71 Enables mRNA 3'-UTR binding activity. Involved in several processes, including determination of adult lifespan; determination of left/right asymmetry in nervous system; and miRNA-mediated gene silencing. Predicted to be part of RISC complex. Expressed in several structures, including AWC; excretory cell; muscle cell; somatic gonad; and vulval precursor cell. WB:WBGene00003300 mir-72 Is affected by several genes including daf-12; eat-2; and glp-4 based on tiling array and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00003301 mir-73 Is affected by several genes including daf-12; eat-2; and glp-4 based on tiling array and RNA-seq studies. Is affected by multi-walled carbon nanotube and graphene oxide based on RNA-seq studies. WB:WBGene00003302 mir-74 Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by Microcystin-LR and sanguinarine based on microarray and RNA-seq studies. WB:WBGene00003303 mir-75 Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by methylmercury hydroxide and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00003304 mir-76 Enriched in neurons based on RNA-seq studies. Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR studies. WB:WBGene00003305 mir-77 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. Used to study Parkinson's disease. WB:WBGene00003306 mir-78 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by Microcystin-LR based on microarray studies. WB:WBGene00003307 mir-79 Expressed in hypodermis. WB:WBGene00003308 mir-80 Involved in regulation of gene expression. Expressed in excretory cell; hypodermis; pharynx; somatic nervous system; and tail neurons. Used to study Parkinson's disease. WB:WBGene00003309 mir-81 Is affected by several genes including eat-2; alg-1; and alg-2 based on RNA-seq studies. WB:WBGene00003310 mir-82 Expressed in amphid neurons; excretory gland cell; and tail neurons. WB:WBGene00003311 mir-83 Expressed in body wall musculature; neurons; and pharynx. Used to study Parkinson's disease. WB:WBGene00003312 mir-84 Predicted to enable translation repressor activity. Involved in several processes, including miRNA-mediated gene silencing by inhibition of translation; negative regulation of Ras protein signal transduction; and positive regulation of development, heterochronic. Expressed in several structures, including P5.ppp; gonad; somatic gonad precursor; touch receptor neurons; and vulval precursor cell. Used to study Parkinson's disease. WB:WBGene00003313 mir-85 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by nicotine based on RNA-seq studies. WB:WBGene00003314 mir-86 Expressed in dorsal nerve cord; nerve ring; tail neurons; and ventral nerve cord. WB:WBGene00003315 mir-87 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. WB:WBGene00003316 C32E12.6 No description available WB:WBGene00003317 C32C4.4 No description available WB:WBGene00003318 mir-90 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by nicotine and sanguinarine based on quantitative PCR and RNA-seq studies. WB:WBGene00003319 mir-124 Expressed in nervous system and tail. Used to study Werner syndrome. Is an ortholog of human MIR124-1 (microRNA 124-1); MIR124-2 (microRNA 124-2); and MIR124-3 (microRNA 124-3). WB:WBGene00003321 mir-228 Expressed in germ line; neuronal sheath cell; and seam cell. WB:WBGene00003322 mir-229 Is affected by several genes including eat-2; alg-1; and alg-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00003323 mir-230 Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by nicotine and sanguinarine based on quantitative PCR and RNA-seq studies. Used to study Parkinson's disease. WB:WBGene00003324 mir-231 Expressed in muscle cell. WB:WBGene00003325 mir-232 Enriched in neurons based on RNA-seq studies. Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine based on RNA-seq studies. WB:WBGene00003326 mir-233 Expressed in intestine. WB:WBGene00003327 mir-234 Expressed in neurons. WB:WBGene00003328 mir-235 Expressed in AMsoL; AMsoR; and hypodermis. WB:WBGene00003329 mir-236 Expressed in pharynx. WB:WBGene00003330 mir-237 Expressed in gonad; seam cell; somatic gonad precursor; and vulval precursor cell. WB:WBGene00003331 mir-238 Is affected by several genes including eat-2; glp-4; and prg-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. Used to study Parkinson's disease. WB:WBGene00003332 mir-239.1 Is affected by several genes including daf-12; eat-2; and glp-4 based on tiling array and RNA-seq studies. Is affected by nicotine based on RNA-seq studies. WB:WBGene00003333 mir-239.2 Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by graphene oxide; sodium arsenite; and paraquat based on RNA-seq studies. WB:WBGene00003334 mir-240 Expressed in intestinal cell. WB:WBGene00003335 mir-241 Involved in miRNA-mediated gene silencing by inhibition of translation and positive regulation of development, heterochronic. Expressed in body wall musculature; excretory canal; hermaphrodite distal tip cell; and touch receptor neurons. Used to study Parkinson's disease. WB:WBGene00003336 mir-242 Is affected by several genes including daf-12; prg-1; and alg-1 based on tiling array and RNA-seq studies. Is affected by nicotine based on quantitative PCR and RNA-seq studies. WB:WBGene00003337 mir-243 Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by nicotine; multi-walled carbon nanotube; and sanguinarine based on quantitative PCR and RNA-seq studies. WB:WBGene00003338 mir-244 Is affected by several genes including eat-2; glp-4; and prg-1 based on RNA-seq studies. Is affected by graphene oxide and nicotine based on RNA-seq studies. WB:WBGene00003339 mir-245 Expressed in neurons. WB:WBGene00003340 mir-246 Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by graphene oxide based on RNA-seq studies. WB:WBGene00003341 mir-247 Expressed in neurons and seam cell. WB:WBGene00003342 mir-248 Is affected by several genes including eat-2; glp-4; and prg-1 based on RNA-seq studies. WB:WBGene00003343 mir-249 Expressed in head neurons and seam cell. WB:WBGene00003344 mir-250 Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. WB:WBGene00003345 mir-251 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. WB:WBGene00003346 mir-252 Is affected by several genes including eat-2; alg-1; and alg-2 based on RNA-seq studies. Is affected by Microcystin-LR based on microarray studies. WB:WBGene00003347 mir-253 Is affected by several genes including eat-2; prg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine based on RNA-seq studies. WB:WBGene00003348 mir-254 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by nicotine and sanguinarine based on RNA-seq studies. WB:WBGene00003349 mir-255 Is affected by several genes including eat-2; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine; multi-walled carbon nanotube; and paraquat based on quantitative PCR and RNA-seq studies. WB:WBGene00003350 mir-256 No description available WB:WBGene00003351 mir-257 Is affected by several genes including alg-1; alg-2; and meg-3 based on RNA-seq studies. Is affected by nicotine based on RNA-seq studies. WB:WBGene00003352 mir-258.1 Is affected by alg-1; alg-2; and alg-5 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR studies. WB:WBGene00003353 mir-259 Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by four chemicals including nicotine; multi-walled carbon nanotube; and graphene oxide based on quantitative PCR; RNA-seq; and microarray studies. WB:WBGene00003354 mir-260 Is affected by several genes including tph-1; glp-4; and cat-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube; nicotine; and sodium arsenite based on RNA-seq studies. WB:WBGene00003355 mir-261 No description available WB:WBGene00003356 mir-262 Is affected by several genes including tph-1; glp-4; and cat-2 based on RNA-seq studies. Is affected by nicotine and multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00003357 mir-264 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00003358 mir-265 No description available WB:WBGene00003359 mir-266 No description available WB:WBGene00003360 mir-267 No description available WB:WBGene00003361 mir-268 Enriched in neurons based on RNA-seq studies. Is affected by daf-12 based on tiling array studies. WB:WBGene00003362 mir-269 Is affected by alg-5 based on RNA-seq studies. WB:WBGene00003363 mir-270 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00003364 mir-271 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00003365 mir-272 No description available WB:WBGene00003366 mir-273 Enables mRNA regulatory element binding translation repressor activity. Involved in asymmetric protein localization involved in cell fate determination; miRNA-mediated gene silencing; and neuroblast fate determination. Expressed in ASEL and ASER. WB:WBGene00003367 mix-1 Predicted to enable chromatin binding activity. Involved in several processes, including dosage compensation by hypoactivation of X chromosome; mitotic chromosome condensation; and positive regulation of nematode male tail tip morphogenesis. Located in chromosome, centromeric region and condensed chromosome. Part of dosage compensation complex. Expressed in AB. Human ortholog(s) of this gene implicated in colon adenocarcinoma. Is an ortholog of human SMC2 (structural maintenance of chromosomes 2). WB:WBGene00003368 mkk-4 Enables mitogen-activated protein kinase kinase kinase binding activity. Involved in axon regeneration; p38MAPK cascade; and regulation of developmental growth. Located in cytoplasm. Expressed in head; neurons; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); invasive ductal carcinoma; and prostate carcinoma in situ. Is an ortholog of human MAP2K4 (mitogen-activated protein kinase kinase 4). WB:WBGene00003369 mlc-1 Predicted to enable myosin heavy chain binding activity. Involved in several processes, including muscle organ development; nematode larval development; and regulation of muscle contraction. Part of muscle myosin complex. Expressed in anal depressor muscle; body wall musculature; pharyngeal muscle cell; pharynx; and vulval muscle. Human ortholog(s) of this gene implicated in distal arthrogryposis type 1C and hypertrophic cardiomyopathy 10. Is an ortholog of human MYL10 (myosin light chain 10); MYL5 (myosin light chain 5); and MYL7 (myosin light chain 7). WB:WBGene00003370 mlc-2 Predicted to enable myosin heavy chain binding activity. Involved in several processes, including nematode larval development; regulation of muscle contraction; and regulation of pharyngeal pumping. Predicted to be located in cytoplasm. Predicted to be part of myosin II complex. Expressed in body wall musculature; pharyngeal muscle cell; pharynx; and vulval muscle. Human ortholog(s) of this gene implicated in distal arthrogryposis type 1C and hypertrophic cardiomyopathy 10. Is an ortholog of human MYL10 (myosin light chain 10); MYL5 (myosin light chain 5); and MYL7 (myosin light chain 7). WB:WBGene00003371 mlc-3 Predicted to enable calcium ion binding activity. Located in striated muscle myosin thick filament. Expressed in head neurons; nervous system; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy 8. Is an ortholog of human MYL3 (myosin light chain 3) and MYL6B (myosin light chain 6B). WB:WBGene00003372 mlc-4 Predicted to enable myosin heavy chain binding activity. Involved in several processes, including cytoskeleton-dependent cytokinesis; embryonic body morphogenesis; and nematode larval development. Located in cytoplasm. Part of filamentous actin. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy and megacystis-microcolon-intestinal hypoperistalsis syndrome. Is an ortholog of human MYL9 (myosin light chain 9). WB:WBGene00003373 mlh-1 Predicted to enable ATP hydrolysis activity. Predicted to be involved in mismatch repair. Predicted to be located in nucleus. Predicted to be part of MutLalpha complex. Human ortholog(s) of this gene implicated in several diseases, including Lynch syndrome (multiple); carcinoma (multiple); and cervix uteri carcinoma in situ. Is an ortholog of human MLH1 (mutL homolog 1). WB:WBGene00003374 mlk-1 Enables protein kinase C binding activity; receptor tyrosine kinase binding activity; and scaffold protein binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of axon extension involved in regeneration; and stress-activated MAPK cascade. Predicted to be located in cytoplasm. Expressed in body wall musculature; hypodermis; intestine; and pharynx. Is an ortholog of human MAP3K21 (mitogen-activated protein kinase kinase kinase 21) and MAP3K9 (mitogen-activated protein kinase kinase kinase 9). WB:WBGene00003375 mlp-1 Predicted to enable metal ion binding activity. Located in striated muscle dense body. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1M and hypertrophic cardiomyopathy 12. Is an ortholog of human CSRP1 (cysteine and glycine rich protein 1); CSRP2 (cysteine and glycine rich protein 2); and CSRP3 (cysteine and glycine rich protein 3). WB:WBGene00003376 mls-1 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in muscle cell fate specification and post-embryonic development. Located in nucleus. Expressed in anal depressor muscle and egg-laying apparatus. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in several diseases, including DiGeorge syndrome; congenital heart disease (multiple); and velocardiofacial syndrome. Is an ortholog of human TBX1 (T-box transcription factor 1). WB:WBGene00003377 mls-2 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including establishment of mitotic spindle orientation; neuron differentiation involved in amphid sensory organ development; and regulation of cell differentiation. Located in nucleus. Expressed in several structures, including AB lineage cell; AWC-ON; M.dla; head; and somatic nervous system. Human ortholog(s) of this gene implicated in oculoauricular syndrome. Is an ortholog of human HMX1 (H6 family homeobox 1). WB:WBGene00003378 mml-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in determination of adult lifespan and negative regulation of transcription by RNA polymerase II. Located in mitochondrion and nucleus. Expressed in excretory cell; hypodermis; intestine; and muscle cell. Is an ortholog of human MLXIP (MLX interacting protein) and MLXIPL (MLX interacting protein like). WB:WBGene00003379 mnm-1 No description available WB:WBGene00003380 mnm-2 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of axon guidance. Located in nucleus. Expressed in several structures, including intestine; neurons; rectum; spermathecal-uterine junction; and vulva. WB:WBGene00003381 mnm-3 No description available WB:WBGene00003382 mnm-4 No description available WB:WBGene00003384 moc-1 Predicted to enable molybdopterin molybdotransferase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process; postsynaptic neurotransmitter receptor diffusion trapping; and synapse organization. Predicted to be located in cytosol; dendrite; and postsynapse. Expressed in tail. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type C. Is an ortholog of human GPHN (gephyrin). WB:WBGene00003385 moc-2 Predicted to enable molybdopterin molybdotransferase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. WB:WBGene00003386 mod-1 Enables serotonin binding activity and serotonin-gated chloride channel activity. Involved in several processes, including behavioral response to starvation; locomotory exploration behavior; and positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway. Located in neuronal cell body and plasma membrane. Expressed in body wall musculature and neurons. Used to study cocaine abuse. WB:WBGene00003387 mod-5 Enables serotonin:sodium:chloride symporter activity. Involved in serotonin uptake. Predicted to be located in neuron projection. Expressed in several structures, including nerve ring. Used to study cocaine abuse. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; alexithymia; and attention deficit hyperactivity disorder. Is an ortholog of human SLC6A4 (solute carrier family 6 member 4). WB:WBGene00003388 moe-3 Predicted to enable mRNA binding activity and metal ion binding activity. Expressed in coelomocyte; gonad; intestine; neurons; and ventral nerve cord. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00003389 mog-1 Predicted to enable 3'-5' RNA helicase activity and RNA binding activity. Involved in feminization of hermaphroditic germ-line. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Expressed widely. Human ortholog(s) of this gene implicated in retinitis pigmentosa 84. Is an ortholog of human DHX38 (DEAH-box helicase 38). WB:WBGene00003390 mog-2 Enables U2 snRNA binding activity. Involved in feminization of hermaphroditic germ-line; germline cell cycle switching, mitotic to meiotic cell cycle; and mRNA 3'-splice site recognition. Located in nucleoplasm. Part of U2 snRNP. Human ortholog(s) of this gene implicated in connective tissue disease. Is an ortholog of human SNRPA1 (small nuclear ribonucleoprotein polypeptide A'). WB:WBGene00003391 mog-3 Involved in feminization of hermaphroditic germ-line and meiotic cell cycle. Located in nucleus. Expressed in germ line. Is an ortholog of human CWC25 (CWC25 spliceosome associated protein homolog). WB:WBGene00003392 mog-4 Predicted to enable RNA binding activity and helicase activity. Involved in developmental growth; developmental process involved in reproduction; and embryonic body morphogenesis. Predicted to be located in nucleus. Is an ortholog of human DHX16 (DEAH-box helicase 16). WB:WBGene00003393 mog-5 Predicted to enable RNA binding activity and RNA helicase activity. Involved in developmental growth; developmental process involved in reproduction; and embryonic body morphogenesis. Predicted to be located in nucleus. Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human DHX8 (DEAH-box helicase 8). WB:WBGene00003394 mom-1 Predicted to enable Wnt-protein binding activity and palmitoleoyltransferase activity. Involved in several processes, including Wnt signaling pathway, regulating spindle positioning; asymmetric protein localization involved in cell fate determination; and embryonic morphogenesis. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in focal dermal hypoplasia. Is an ortholog of human PORCN (porcupine O-acyltransferase). WB:WBGene00003395 mom-2 Enables receptor tyrosine kinase binding activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; embryonic morphogenesis; and neuron migration. Predicted to be located in extracellular space. Expressed in several structures, including HSN; P5.ppp; P7.paa; anchor cell; and epithelial cell. WB:WBGene00003396 mom-4 Enables MAP kinase kinase kinase activity. Involved in several processes, including cell fate commitment; embryonic digestive tract morphogenesis; and signal transduction. Located in striated muscle dense body. Expressed in BAGL and BAGR. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); frontometaphyseal dysplasia 2; and intrinsic cardiomyopathy (multiple). Is an ortholog of human MAP3K7 (mitogen-activated protein kinase kinase kinase 7). WB:WBGene00003397 mom-5 Predicted to enable Wnt receptor activity and Wnt-protein binding activity. Involved in several processes, including embryonic morphogenesis; neuron migration; and regulation of locomotion. Predicted to be located in plasma membrane. Expressed in several structures, including QL.a; anus; gonad; nervous system; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including Williams-Beuren syndrome; nonsyndromic congenital nail disorder 1; and omodysplasia 2. Is an ortholog of human FZD1 (frizzled class receptor 1); FZD2 (frizzled class receptor 2); and FZD7 (frizzled class receptor 7). WB:WBGene00003398 mor-1 No description available WB:WBGene00003399 mor-2 No description available WB:WBGene00003400 dapk-1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and positive regulation of apoptotic process. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in urinary bladder cancer. Is an ortholog of human DAPK1 (death associated protein kinase 1). WB:WBGene00003401 mpk-1 Enables MAP kinase activity. Involved in several processes, including determination of adult lifespan; intracellular signal transduction; and positive regulation of nitrogen compound metabolic process. Located in cytoplasm and nucleus. Expressed in F cell; U cell; germ line; gonad; and oocyte. Used to study cancer. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Noonan syndrome 13; carcinoma (multiple); and childhood pilocytic astrocytoma. Is an ortholog of human MAPK1 (mitogen-activated protein kinase 1). WB:WBGene00003402 mpk-2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in prostate cancer. Is an ortholog of human MAPK7 (mitogen-activated protein kinase 7). WB:WBGene00003403 mps-1 Enables potassium channel regulator activity and protein serine/threonine kinase activity. Involved in several processes, including hyperosmotic response; mechanosensory behavior; and negative regulation of potassium ion transport. Located in axolemma; dendrite membrane; and neuronal cell body membrane. Part of voltage-gated potassium channel complex. Expressed in amphid neurons; touch receptor neurons; and vulva. WB:WBGene00003404 mpz-1 Enables GTPase activating protein binding activity. Located in axon. Expressed in body wall musculature; nerve ring; neurons; and vulval muscle. Human ortholog(s) of this gene implicated in hydrocephalus. Is an ortholog of human MPDZ (multiple PDZ domain crumbs cell polarity complex component) and PATJ (PATJ crumbs cell polarity complex component). WB:WBGene00003405 mre-11 Predicted to enable single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in DNA damage response and nucleic acid metabolic process. Located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lynch syndrome; endometrial cancer; and gastrointestinal system cancer (multiple). Is an ortholog of human MRE11 (MRE11 homolog, double strand break repair nuclease). WB:WBGene00003406 mrg-1 Involved in several processes, including protein localization to euchromatin; regulation of transcription by RNA polymerase II; and sexual reproduction. Located in autosome. Part of euchromatin. Expressed in several structures, including Caa; Cpa; Psub4; oocyte; and somatic cell. Is an ortholog of human MORF4L2 (mortality factor 4 like 2). WB:WBGene00003407 mrp-1 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in dauer larval development; regulatory ncRNA-mediated post-transcriptional gene silencing; and stress response to metal ion. Located in plasma membrane. Expressed in several structures, including intestine; pharyngeal-intestinal valve; pharynx; rectal valve cell; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including bile duct disease (multiple); leukemia (multiple); and lung disease (multiple). Is an ortholog of human ABCC3 (ATP binding cassette subfamily C member 3). WB:WBGene00003408 mrp-2 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including bile duct disease (multiple); leukemia (multiple); and lung disease (multiple). Is an ortholog of human ABCC3 (ATP binding cassette subfamily C member 3). WB:WBGene00003409 mrp-3 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00003410 mrp-4 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in lipid transport involved in lipid storage and lysosome organization. Located in endocytic vesicle and gut granule. WB:WBGene00003411 mrp-5 Enables ABC-type vitamin B12 transporter activity. Involved in cobalamin transport. Predicted to be located in membrane. Expressed in several structures, including body wall musculature; hypodermis; intestine; muscle cell; and pharynx. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human ABCC12 (ATP binding cassette subfamily C member 12) and ABCC5 (ATP binding cassette subfamily C member 5). WB:WBGene00003412 mrp-6 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human ABCC4 (ATP binding cassette subfamily C member 4). WB:WBGene00003413 mrp-7 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in response to methylmercury. Predicted to be located in membrane. Expressed in DA neuron. Human ortholog(s) of this gene implicated in several diseases, including bile duct disease (multiple); leukemia (multiple); and lung disease (multiple). Is an ortholog of human ABCC1 (ATP binding cassette subfamily C member 1) and ABCC2 (ATP binding cassette subfamily C member 2). WB:WBGene00003414 mrp-8 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in arterial calcification of infancy; coronary artery disease; and pseudoxanthoma elasticum. Is an ortholog of human ABCC6 (ATP binding cassette subfamily C member 6). WB:WBGene00003415 mars-1 Predicted to enable methionine-tRNA ligase activity. Predicted to be involved in methionyl-tRNA aminoacylation. Predicted to be located in cytosol. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2U and trichothiodystrophy. Is an ortholog of human MARS1 (methionyl-tRNA synthetase 1). WB:WBGene00003416 mars-2 No description available WB:WBGene00003417 mrt-2 Predicted to enable 3'-5' exonuclease activity and damaged DNA binding activity. Involved in DNA damage response and telomere maintenance via telomerase. Predicted to be located in nucleus. Predicted to be part of checkpoint clamp complex. Is an ortholog of human RAD1 (RAD1 checkpoint DNA exonuclease). WB:WBGene00003418 msh-2 Predicted to enable double-strand/single-strand DNA junction binding activity and mismatched DNA binding activity. Involved in DNA damage response; maintenance of DNA repeat elements; and reproduction. Predicted to be located in nucleus. Predicted to be part of MutSalpha complex. Human ortholog(s) of this gene implicated in several diseases, including Lynch syndrome (multiple); carcinoma (multiple); and cervix uteri carcinoma in situ. Is an ortholog of human MSH2 (mutS homolog 2). WB:WBGene00003419 msh-3 No description available WB:WBGene00003420 msh-4 Enriched in Z1.p; Z4.a; germline precursor cell; gon_male_dtc anterior; and gon_male_dtc posterior based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00003421 msh-5 Predicted to enable double-stranded DNA binding activity. Involved in chiasma assembly. Located in nucleus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; primary ovarian insufficiency 13; and spermatogenic failure. Is an ortholog of human MSH5 (mutS homolog 5). WB:WBGene00003422 msh-6 Predicted to enable four-way junction DNA binding activity and mismatched DNA binding activity. Involved in maintenance of DNA repeat elements and mismatch repair. Predicted to be located in nucleus. Predicted to be part of MutSalpha complex. Used to study Lynch syndrome. Human ortholog(s) of this gene implicated in several diseases, including colorectal carcinoma; hereditary nonpolyposis colorectal cancer type 5; and mismatch repair cancer syndrome. Is an ortholog of human MSH6 (mutS homolog 6). WB:WBGene00003423 msi-1 Enables mRNA binding activity. Involved in nervous system process. Located in cytoplasm. Expressed in SMDVL; head neurons; and intestine. Is an ortholog of human MSI1 (musashi RNA binding protein 1) and MSI2 (musashi RNA binding protein 2). WB:WBGene00003424 msp-3 Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and spermatocyte. WB:WBGene00003425 msp-10 Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003426 msp-19 Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003427 msp-24 Expressed in gonad; oocyte; and sperm. WB:WBGene00003428 msp-29 Expressed in gonad; oocyte; and sperm. WB:WBGene00003429 msp-31 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003430 msp-32 Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003431 msp-33 Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003432 msp-36 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003433 msp-37 Expressed in gonad; oocyte; and sperm. WB:WBGene00003434 msp-38 Involved in oocyte maturation and positive regulation of smooth muscle contraction. Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003435 msp-40 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003436 msp-41 Expressed in gonad; oocyte; and sperm. WB:WBGene00003437 msp-42 Expressed in gonad; oocyte; and sperm. WB:WBGene00003438 msp-45 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003439 msp-46 Expressed in gonad; oocyte; and sperm. WB:WBGene00003440 msp-47 Expressed in gonad; oocyte; and sperm. WB:WBGene00003441 msp-48 Expressed in gonad; oocyte; and sperm. WB:WBGene00003442 msp-49 Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003443 msp-50 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003444 msp-51 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003445 msp-52 Expressed in gonad; oocyte; and sperm. WB:WBGene00003446 msp-53 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003447 msp-54 Expressed in gonad; oocyte; and sperm. WB:WBGene00003448 msp-55 Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003449 msp-56 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003450 msp-57 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003451 msp-58 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003452 msp-59 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003453 msp-60 Expressed in gonad; oocyte; and sperm. WB:WBGene00003454 msp-61 Expressed in gonad; oocyte; and sperm. WB:WBGene00003455 msp-62 Expressed in gonad; oocyte; and sperm. WB:WBGene00003456 msp-63 Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003457 msp-64 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003458 msp-65 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003459 msp-70 Expressed in gonad; oocyte; and sperm. WB:WBGene00003460 msp-71 Expressed in gonad; oocyte; and sperm. WB:WBGene00003461 msp-72 Expressed in gonad; oocyte; and sperm. WB:WBGene00003462 msp-74 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003463 msp-76 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003464 msp-77 Involved in oocyte maturation; positive regulation of MAPK cascade; and positive regulation of smooth muscle contraction. Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003465 msp-78 Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003466 msp-79 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003467 msp-81 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003468 msp-113 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003469 msp-142 Expressed in gonad; oocyte; and sperm. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00003470 msp-152 Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm. WB:WBGene00003471 mtd-1 Involved in positive regulation of detection of mechanical stimulus involved in sensory perception of touch. Located in plasma membrane. Expressed in touch receptor neurons. WB:WBGene00003472 mtk-1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in MAPK cascade and phosphorylation. Predicted to be located in cytoplasm. Is an ortholog of human MAP3K4 (mitogen-activated protein kinase kinase kinase 4). WB:WBGene00003473 mtl-1 Enables cadmium ion binding activity and zinc ion binding activity. Involved in response to heat and response to metal ion. Predicted to be located in cytoplasm. Expressed in intestine; pharynx; and terminal bulb. WB:WBGene00003474 mtl-2 Enables cadmium ion binding activity and zinc ion binding activity. Involved in response to cadmium ion and response to heat. Expressed in intestinal cell and intestine. WB:WBGene00003475 mtm-1 Enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity; phosphatidylinositol-3-phosphate phosphatase activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in negative regulation of engulfment of apoptotic cell and phospholipid dephosphorylation. Located in apical cortex; cytosol; and plasma membrane. Expressed in several structures, including coelomocyte; hermaphrodite somatic gonadal cell; neurons; pharynx; and vulva. Used to study centronuclear myopathy. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4B1 and congenital structural myopathy. Is an ortholog of human MTM1 (myotubularin 1); MTMR1 (myotubularin related protein 1); and MTMR2 (myotubularin related protein 2). WB:WBGene00003476 mtm-3 Enables inositol bisphosphate phosphatase activity and phosphatidylinositol phosphate phosphatase activity. Involved in several processes, including determination of adult lifespan; positive regulation of autophagosome maturation; and regulation of endocytosis. Located in cytoplasm. Expressed in body wall musculature and head neurons. Is an ortholog of human MTMR3 (myotubularin related protein 3). WB:WBGene00003477 mtm-5 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in cytoplasm and membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4B2 and Charcot-Marie-Tooth disease type 4B3. Is an ortholog of human SBF1 (SET binding factor 1) and SBF2 (SET binding factor 2). WB:WBGene00003478 mtm-6 Enables phosphatase binding activity. Involved in several processes, including nematode larval development; phosphatidylinositol metabolic process; and pinocytosis. Located in apical plasma membrane and cytosol. Expressed in several structures, including anal depressor muscle; coelomocyte; intestinal cell; preanal ganglion; and tail. Used to study centronuclear myopathy. Is an ortholog of human MTMR6 (myotubularin related protein 6); MTMR7 (myotubularin related protein 7); and MTMR8 (myotubularin related protein 8). WB:WBGene00003479 mtm-9 Enables phosphatase binding activity. Involved in pinocytosis and regulation of cell migration. Located in cytosol and plasma membrane. Expressed in several structures, including CAN; PDE; coelomocyte; epithelial cell; and vulva. Used to study centronuclear myopathy. Is an ortholog of human MTMR9 (myotubularin related protein 9). WB:WBGene00003480 klf-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of gene expression and regulation of lipid metabolic process. Predicted to be located in nucleus. Expressed in germ line and vulva. Used to study obesity. Is an ortholog of human KLF12 (KLF transcription factor 12); KLF2 (KLF transcription factor 2); and KLF8 (KLF transcription factor 8). WB:WBGene00003481 mua-2 No description available WB:WBGene00003482 mua-3 Predicted to enable collagen binding activity and intermediate filament binding activity. Involved in cell-matrix adhesion. Located in hemidesmosome and intermediate filament. Expressed in several structures, including amphid neurons; enteric muscle; excretory system; phasmid sensillum; and rectum. Used to study Marfan syndrome. Human ortholog(s) of this gene implicated in multiple epiphyseal dysplasia 5 and osteoarthritis. Is an ortholog of human MATN3 (matrilin 3). WB:WBGene00003483 mua-4 No description available WB:WBGene00003484 mua-5 No description available WB:WBGene00003485 mua-6 Predicted to be a structural constituent of cytoskeleton. Involved in cell-cell adhesion. Located in hemidesmosome. Expressed in hypodermis; touch receptor neurons; uterus; and ventral cord neurons. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). WB:WBGene00003486 mua-7 No description available WB:WBGene00003487 mua-8 No description available WB:WBGene00003488 mua-9 No description available WB:WBGene00003489 mua-10 No description available WB:WBGene00003490 mud-1 No description available WB:WBGene00003491 mum-1 No description available WB:WBGene00003492 mum-2 No description available WB:WBGene00003493 mum-3 No description available WB:WBGene00003494 mup-1 No description available WB:WBGene00003495 mup-2 Predicted to enable tropomyosin binding activity. Involved in several processes, including axonal fasciculation; muscle structure development; and ovulation. Predicted to be part of troponin complex. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; intrinsic cardiomyopathy (multiple); and muscle tissue disease (multiple). Is an ortholog of human TNNT1 (troponin T1, slow skeletal type); TNNT2 (troponin T2, cardiac type); and TNNT3 (troponin T3, fast skeletal type). WB:WBGene00003496 mup-3 No description available WB:WBGene00003497 mup-4 Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Located in hemidesmosome. Part of hemidesmosome associated protein complex. Expressed in body wall musculature; hypodermis; pharynx; touch receptor neurons; and vulval cell. Human ortholog(s) of this gene implicated in multiple epiphyseal dysplasia 5 and osteoarthritis. Is an ortholog of human MATN2 (matrilin 2) and MATN3 (matrilin 3). WB:WBGene00003498 mut-1 No description available WB:WBGene00003499 mut-2 Predicted to enable nucleotidyltransferase activity. Involved in several processes, including embryo development; meiotic chromosome segregation; and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in mutator focus. Expressed in germ line. WB:WBGene00003500 mut-3 No description available WB:WBGene00003501 mut-4 No description available WB:WBGene00003502 mut-5 No description available WB:WBGene00003503 mut-6 No description available WB:WBGene00003504 mut-7 Predicted to enable 3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing. Involved in obsolete negative regulation of transposition, DNA-mediated; olfactory learning; and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in cytosol; mutator focus; and nucleus. Expressed in AWCL; AWCR; and somatic cell. Is an ortholog of human EXD3 (exonuclease 3'-5' domain containing 3). WB:WBGene00003506 mut-9 No description available WB:WBGene00003507 mut-14 Predicted to enable RNA binding activity and RNA helicase activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in mutator focus. Expressed in germ cell and germ line. WB:WBGene00003508 mut-16 Involved in obsolete negative regulation of transposition, DNA-mediated; regulatory ncRNA-mediated post-transcriptional gene silencing; and siRNA processing. Located in mutator focus and nucleus. Expressed in several structures, including germ cell; germ line; and somatic cell. WB:WBGene00003509 mxl-1 Enables protein domain specific binding activity and protein heterodimerization activity. Contributes to sequence-specific DNA binding activity. Involved in determination of adult lifespan. Located in nucleus. Part of transcription regulator complex. Expressed in tail neurons. Human ortholog(s) of this gene implicated in lung small cell carcinoma and pheochromocytoma. Is an ortholog of human MAX (MYC associated factor X). WB:WBGene00003510 mxl-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in determination of adult lifespan. Acts upstream of or within negative regulation of gene expression. Located in cytoplasm and nucleus. Expressed in hypodermis and intestine. Is an ortholog of human MLX (MAX dimerization protein MLX). WB:WBGene00003511 mxl-3 Enables DNA-binding transcription factor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II; regulation of fatty acid biosynthetic process; and response to food. Acts upstream of with a positive effect on insulin receptor signaling pathway. Located in cytoplasm and nucleus. Expressed in AWCL; AWCR; neurons; and pharynx. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in lung small cell carcinoma and pheochromocytoma. Is an ortholog of human MAX (MYC associated factor X). WB:WBGene00003514 myo-2 Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in muscle contraction and sarcomere organization. Predicted to be located in cytoplasm and myosin filament. Predicted to be part of muscle myosin complex. Expressed in neurons and pharynx. Human ortholog(s) of this gene implicated in several diseases, including congenital heart disease (multiple); distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3). WB:WBGene00003515 myo-3 Enables cytoskeletal motor activity. Involved in locomotory behavior and positive regulation of ovulation. Located in A band and striated muscle myosin thick filament. Expressed in body wall musculature; enteric muscle; gonad; vulval muscle; and in male. Human ortholog(s) of this gene implicated in several diseases, including congenital heart disease (multiple); distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3). WB:WBGene00003516 nab-1 Predicted to enable actin filament binding activity. Involved in synapse assembly. Located in actin cytoskeleton and presynapse. Expressed in several structures, including egg-laying apparatus; excretory canal; hermaphrodite distal tip cell; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; hepatocellular carcinoma; and schizophrenia. Is an ortholog of human PPP1R9A (protein phosphatase 1 regulatory subunit 9A) and PPP1R9B (protein phosphatase 1 regulatory subunit 9B). WB:WBGene00003517 nac-1 Enables low-affinity sodium:dicarboxylate symporter activity and succinate transmembrane transporter activity. Involved in succinate transport. Predicted to be located in membrane. Expressed in alimentary system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 25. Is an ortholog of human SLC13A2 (solute carrier family 13 member 2) and SLC13A5 (solute carrier family 13 member 5). WB:WBGene00003518 nac-2 Enables citrate transmembrane transporter activity and succinate transmembrane transporter activity. Involved in several processes, including carboxylic acid transport; determination of adult lifespan; and regulation of growth. Predicted to be located in membrane. Expressed in rect_D; rect_VL; and rect_VR. Is an ortholog of human SLC13A2 (solute carrier family 13 member 2). WB:WBGene00003519 nac-3 Enables high-affinity sodium:dicarboxylate symporter activity and succinate transmembrane transporter activity. Involved in determination of adult lifespan and succinate transport. Predicted to be located in membrane. Expressed in alimentary system. Is an ortholog of human SLC13A2 (solute carrier family 13 member 2). WB:WBGene00003520 nas-1 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in arcade cell; marginal cell; and pharyngeal muscle cell. WB:WBGene00003521 nas-2 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in head; intestine; and rectal gland cell. WB:WBGene00003522 nas-3 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in PDE; hypodermal cell; intestine; and pharyngeal muscle cell. WB:WBGene00003523 nas-4 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in intestine; marginal cell; and pharynx. WB:WBGene00003524 nas-5 Predicted to enable metalloendopeptidase activity. Involved in pharyngeal pumping and pharynx development. Predicted to be located in extracellular region. Expressed in marginal cell; pharyngeal gland cell; rectal gland cell; and uterine seam cell. WB:WBGene00003525 nas-6 Predicted to enable metalloendopeptidase activity. Involved in pharyngeal pumping and pharynx development. Predicted to be located in extracellular region. Expressed in body wall musculature; hyp7 syncytium; intestine; mc2; and pharyngeal muscle cell. Is an ortholog of human MEP1A (meprin A subunit alpha) and MEP1B (meprin A subunit beta). WB:WBGene00003526 nas-7 Predicted to enable metalloendopeptidase activity. Involved in pharyngeal pumping and pharynx development. Predicted to be located in extracellular region. Expressed in several structures, including arcade cell; hypodermis; pharyngeal cell; spermatheca; and vulva. Is an ortholog of human ASTL (astacin like metalloendopeptidase). WB:WBGene00003527 nas-8 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Is an ortholog of human ASTL (astacin like metalloendopeptidase); MEP1A (meprin A subunit alpha); and MEP1B (meprin A subunit beta). WB:WBGene00003528 nas-9 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in hyp7 syncytium; spermatheca; and uterus. WB:WBGene00003529 nas-10 Predicted to enable metalloendopeptidase activity and zinc ion binding activity. Predicted to be involved in proteolysis. WB:WBGene00003530 nas-11 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in hyp7 syncytium; intestine; and neuronal sheath cell. WB:WBGene00003531 nas-12 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in g1AL; g1AR; g1P; g2L; and g2R. WB:WBGene00003532 nas-13 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in IL2L; IL2R; and amphid neurons. Is an ortholog of human ASTL (astacin like metalloendopeptidase). WB:WBGene00003533 nas-14 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in marginal cell and pharyngeal muscle cell. WB:WBGene00003534 nas-15 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in marginal cell; pm3; pm4; pm5; and pm6. WB:WBGene00003535 nas-16 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in intestine. WB:WBGene00003536 nas-17 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. WB:WBGene00003537 nas-18 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. WB:WBGene00003538 nas-19 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in marginal cell; pharyngeal muscle cell; rectal gland cell; and spermatheca. WB:WBGene00003539 nas-20 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. WB:WBGene00003540 nas-21 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in gonad; hyp7 syncytium; intestine; and uterine seam cell. WB:WBGene00003541 nas-22 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. WB:WBGene00003542 nas-23 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in hyp7 syncytium; intestine; pharyngeal muscle cell; and rectum. WB:WBGene00003543 nas-24 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. WB:WBGene00003544 nas-25 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in arcade cell; marginal cell; and rectal gland cell. WB:WBGene00003545 nas-27 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in hyp7 syncytium; intestine; and rectal epithelium. WB:WBGene00003546 nas-28 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in coelomocyte; intestine; and pharyngeal muscle cell. WB:WBGene00003547 nas-29 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. WB:WBGene00003548 nas-30 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Expressed in rectal epithelium. WB:WBGene00003549 nas-31 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in AMshL; AMshR; PHshL; PHshR; and head. WB:WBGene00003550 nas-32 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in head mesodermal cell; head neurons; and non-striated muscle. WB:WBGene00003551 nas-33 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in hyp12; intestine; and tail hypodermis. WB:WBGene00003552 nas-36 Predicted to enable metalloendopeptidase activity. Involved in molting cycle. Predicted to be located in extracellular region. Expressed in hypodermal cell and vulva. WB:WBGene00003553 nas-37 Enables metalloendopeptidase activity. Involved in collagen and cuticulin-based cuticle development and ecdysis, collagen and cuticulin-based cuticle. Located in extracellular region. Expressed in cuticle; epithelial cell; intestine; and rectal gland cell. WB:WBGene00003554 nas-38 Predicted to enable metalloendopeptidase activity. Involved in PERK-mediated unfolded protein response. Predicted to be located in extracellular region. WB:WBGene00003555 nas-39 Predicted to enable metalloendopeptidase activity. Predicted to be involved in dorsal/ventral pattern formation and protein processing. Predicted to be located in extracellular space. Expressed in neurons and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in atrial heart septal defect 6; coronary artery disease; and osteogenesis imperfecta type 13. Is an ortholog of human BMP1 (bone morphogenetic protein 1) and TLL2 (tolloid like 2). WB:WBGene00003556 nas-40 Enriched in male based on RNA-seq studies. Is affected by several genes including rrf-3; tph-1; and cat-2 based on RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00003558 nca-2 Predicted to enable monoatomic cation channel activity. Involved in positive regulation of GABAergic synaptic transmission; positive regulation of cholinergic synaptic transmission; and positive regulation of locomotion. Predicted to be located in plasma membrane. Expressed in several structures, including intestine; pharyngeal neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in congenital limbs-face contractures-hypotonia-developmental delay syndrome. Is an ortholog of human NALCN (sodium leak channel, non-selective). WB:WBGene00003559 ncl-1 Enables translation repressor activity. Involved in several processes, including negative regulation of DNA-templated transcription; negative regulation of ribosome biogenesis; and nucleologenesis. Located in cytoplasm. Expressed in head and tail. Is an ortholog of human TRIM3 (tripartite motif containing 3). WB:WBGene00003560 ncl-2 No description available WB:WBGene00003561 ncr-1 Predicted to enable cholesterol binding activity. Involved in several processes, including cholesterol homeostasis; positive regulation of growth rate; and regulation of egg-laying behavior. Predicted to be located in late endosome; lysosome; and plasma membrane. Expressed in several structures, including excretory cell; head neurons; hypodermis; lumbar neurons; and pharynx. Used to study Niemann-Pick disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease type C1. Is an ortholog of human NPC1 (NPC intracellular cholesterol transporter 1). WB:WBGene00003562 ncr-2 Predicted to enable cholesterol binding activity. Involved in cholesterol homeostasis; cholesterol transport; and nematode larval development. Predicted to be located in plasma membrane. Expressed in XXXL; XXXR; gonadal sheath cell; spermatheca; and ventral nerve cord. Used to study Niemann-Pick disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease type C1. Is an ortholog of human NPC1 (NPC intracellular cholesterol transporter 1). WB:WBGene00003563 ncs-1 Predicted to enable calcium ion binding activity and calcium sensitive guanylate cyclase activator activity. Involved in chemosensory behavior; chemotaxis; and response to alkaline pH. Located in neuronal cell body. Expressed in head neurons; pm1; and tail neurons. Is an ortholog of human NCS1 (neuronal calcium sensor 1). WB:WBGene00003564 ncs-2 Predicted to enable calcium ion binding activity. Expressed in GABAergic neurons; cholinergic neurons; motor neurons; nervous system; and ventral nerve cord. Is an ortholog of human RCVRN (recoverin). WB:WBGene00003565 ncs-3 Predicted to enable calcium ion binding activity. WB:WBGene00003566 ncx-1 Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in calcium ion import across plasma membrane and sodium ion transmembrane transport. Predicted to be located in axon; postsynapse; and sarcolemma. Expressed in AIYL and AIYR. Human ortholog(s) of this gene implicated in Alzheimer's disease and pulmonary hypertension. Is an ortholog of human SLC8A1 (solute carrier family 8 member A1) and SLC8A2 (solute carrier family 8 member A2). WB:WBGene00003567 ncx-2 Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in calcium ion import across plasma membrane and sodium ion transmembrane transport. Predicted to be located in axon; postsynapse; and sarcolemma. Expressed in non-striated muscle and pharynx. Human ortholog(s) of this gene implicated in Alzheimer's disease and pulmonary hypertension. Is an ortholog of human SLC8A2 (solute carrier family 8 member A2). WB:WBGene00003568 ncx-3 Predicted to enable calcium:sodium antiporter activity; calmodulin binding activity; and metal ion binding activity. Predicted to be involved in metal ion transport. Predicted to be located in membrane. Expressed in dorsal nerve cord; head neurons; phasmid neurons; and ventral nerve cord. WB:WBGene00003569 ncx-4 Predicted to enable calcium channel activity and calcium, potassium:sodium antiporter activity. Predicted to be involved in calcium ion transmembrane transport and intracellular calcium ion homeostasis. Predicted to be located in membrane. Expressed in amphid neurons; labial sensillum; somatic nervous system; and tail neurons. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1D. Is an ortholog of human SLC24A1 (solute carrier family 24 member 1) and SLC24A2 (solute carrier family 24 member 2). WB:WBGene00003570 ncx-5 Predicted to enable calcium channel activity and calcium, potassium:sodium antiporter activity. Predicted to be involved in calcium ion transmembrane transport and intracellular calcium ion homeostasis. Predicted to be located in membrane. Expressed in oxygen sensory neurons. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1D. Is an ortholog of human SLC24A1 (solute carrier family 24 member 1) and SLC24A2 (solute carrier family 24 member 2). WB:WBGene00003571 ncx-6 Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in intracellular calcium ion homeostasis and monoatomic cation transport. Predicted to be located in membrane. Expressed in ADLL and ADLR. Is an ortholog of human SLC8B1 (solute carrier family 8 member B1). WB:WBGene00003572 ncx-7 Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in intracellular calcium ion homeostasis and monoatomic cation transport. Predicted to be located in membrane. Expressed in ADLL; ADLR; amphid neurons; and tail neurons. Is an ortholog of human SLC8B1 (solute carrier family 8 member B1). WB:WBGene00003573 ncx-8 Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in intracellular calcium ion homeostasis and monoatomic cation transport. Predicted to be located in membrane. Expressed in intestine and pharynx. Is an ortholog of human SLC8B1 (solute carrier family 8 member B1). WB:WBGene00003574 ncx-9 Enables calcium:sodium antiporter activity. Involved in calcium export from the mitochondrion and regulation of dorsal/ventral axon guidance. Located in mitochondrion. Expressed in head neurons; neurons; and seam cell. Is an ortholog of human SLC8B1 (solute carrier family 8 member B1). WB:WBGene00003575 ncx-10 Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in intracellular calcium ion homeostasis and monoatomic cation transport. Predicted to be located in membrane. Expressed in pharyngeal muscle cell and terminal bulb. Is an ortholog of human SLC8B1 (solute carrier family 8 member B1). WB:WBGene00003576 ndc-80 Enables protein domain specific binding activity. Involved in several processes, including chromosome organization; gonad morphogenesis; and positive regulation of kinetochore assembly. Located in kinetochore. Part of Ndc80 complex. Human ortholog(s) of this gene implicated in colorectal cancer; lung non-small cell carcinoma; and stomach cancer. Is an ortholog of human NDC80 (NDC80 kinetochore complex component). WB:WBGene00003577 ndg-4 Predicted to be located in membrane. Expressed in hyp3; hyp5; hypodermal cell; and intestine. WB:WBGene00003578 ndx-1 Predicted to enable 8-oxo-GDP phosphatase activity; 8-oxo-dGDP phosphatase activity; and magnesium ion binding activity. Located in sarcoplasmic reticulum. Expressed in spermatheca and vulval muscle. Is an ortholog of human NUDT18 (nudix hydrolase 18). WB:WBGene00003579 ndx-2 Predicted to enable ADP-ribose diphosphatase activity. Predicted to be involved in nucleoside phosphate metabolic process and ribose phosphate metabolic process. Predicted to be located in nucleus. Is an ortholog of human NUDT5 (nudix hydrolase 5). WB:WBGene00003580 ndx-3 Predicted to enable CoA pyrophosphatase activity and metal ion binding activity. Is an ortholog of human NUDT8 (nudix hydrolase 8). WB:WBGene00003581 ndx-4 Enables 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity and bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity. Involved in nucleotide metabolic process. Is an ortholog of human NUDT2 (nudix hydrolase 2). WB:WBGene00003582 dcap-2 Enables 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity. Involved in several processes, including deadenylation-dependent decapping of nuclear-transcribed mRNA; determination of adult lifespan; and nematode larval development. Located in P granule and P-body. Is an ortholog of human DCP2 (decapping mRNA 2). WB:WBGene00003583 ndx-6 Predicted to enable ADP-ribose diphosphatase activity and metal ion binding activity. Is an ortholog of human NUDT9 (nudix hydrolase 9). WB:WBGene00003584 ndx-7 Predicted to enable hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides and metal ion binding activity. Is an ortholog of human NUDT19 (nudix hydrolase 19). WB:WBGene00003585 ndx-8 Enables CoA pyrophosphatase activity; hydroxymethylglutaryl-CoA hydrolase activity; and succinyl-CoA hydrolase activity. Involved in coenzyme A catabolic process. Predicted to be located in peroxisome. Is an ortholog of human NUDT7 (nudix hydrolase 7). WB:WBGene00003586 ndx-9 Predicted to enable NADH pyrophosphatase activity. Predicted to be involved in NAD catabolic process; NADH metabolic process; and NADP catabolic process. Predicted to be located in peroxisome. Is an ortholog of human NUDT13 (nudix hydrolase 13). WB:WBGene00003587 ned-8 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Involved in negative regulation of DNA damage response, signal transduction by p53 class mediator; negative regulation of gene expression; and regulation of apoptotic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Parkinson's disease and malignant astrocytoma. Is an ortholog of human NEDD8 (NEDD8 ubiquitin like modifier). WB:WBGene00003588 nex-1 Enables heparin binding activity and phospholipid binding activity. Involved in engulfment of apoptotic cell. Located in intracellular membrane-bounded organelle and plasma membrane. Expressed in hypodermis; pharynx; spermathecal-uterine junction; uterine toroidal epithelial cell; and vulva. WB:WBGene00003589 nex-2 Enables phospholipid binding activity and sulfur compound binding activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); and reproductive organ cancer (multiple). Is an ortholog of human ANXA7 (annexin A7). WB:WBGene00003590 nex-3 Enables phospholipid binding activity and sulfur compound binding activity. Predicted to be located in cytoplasm. Is an ortholog of human ANXA3 (annexin A3). WB:WBGene00003591 nex-4 Predicted to enable calcium ion binding activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in cholangiocarcinoma; hepatocellular carcinoma; and pancreatic ductal carcinoma. Is an ortholog of several human genes including ANXA10 (annexin A10); ANXA8 (annexin A8); and ANXA9 (annexin A9). WB:WBGene00003592 nfi-1 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of transcription by RNA polymerase II; regulation of egg-laying behavior; and regulation of pharyngeal pumping. Acts upstream of or within determination of adult lifespan. Predicted to be located in nucleus. Expressed in several structures, including body wall musculature; egg-laying apparatus; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in Marshall-Smith syndrome; NFIA-related disorder; and Sotos syndrome 2. Is an ortholog of human NFIA (nuclear factor I A). WB:WBGene00003593 nfm-1 Predicted to enable actin binding activity and integrin binding activity. Predicted to be involved in several processes, including regulation of cellular localization; regulation of gliogenesis; and regulation of hippo signaling. Predicted to be located in several cellular components, including adherens junction; apical part of cell; and filopodium. Expressed in excretory gland cell; gonadal sheath cell; intestinal cell; pharyngeal muscle cell; and rectal gland cell. Human ortholog(s) of this gene implicated in several diseases, including acoustic neuroma; gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human NF2 (NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor). WB:WBGene00003594 nft-1 Predicted to enable bis(5'-adenosyl)-triphosphatase activity and deaminated glutathione amidase activity. Predicted to be involved in amide catabolic process and nucleobase-containing compound metabolic process. Expressed in tail. Is an ortholog of human NIT1 (nitrilase 1). WB:WBGene00003595 ngn-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Involved in several processes, including axon development; negative regulation of gliogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including ABaraappaa; ABplpapaaa; ABplpapaap; MSpa; and ventral ganglion. Human ortholog(s) of this gene implicated in congenital malabsorptive diarrhea 4; glucose intolerance; and type 2 diabetes mellitus. Is an ortholog of human NEUROG3 (neurogenin 3). WB:WBGene00003596 ngp-1 Predicted to enable GTP binding activity. Predicted to be located in nucleolus. Is an ortholog of human GNL2 (G protein nucleolar 2). WB:WBGene00003597 nhl-1 Enables ubiquitin-protein transferase activity. Involved in protein ubiquitination. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2R. Is an ortholog of human TRIM2 (tripartite motif containing 2). WB:WBGene00003598 nhl-2 Enables DEAD/H-box RNA helicase binding activity. Involved in positive regulation of development, heterochronic; protein localization to cell cortex; and regulation of establishment of cell polarity. Located in P granule and P-body. Expressed in several structures, including germ line. Is an ortholog of human TRIM45 (tripartite motif containing 45). WB:WBGene00003599 nhl-3 Predicted to enable ubiquitin protein ligase activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); and pre-eclampsia. Is an ortholog of human PML (PML nuclear body scaffold) and TRIM45 (tripartite motif containing 45). WB:WBGene00003600 nhr-1 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in regulation of response to osmotic stress. Predicted to be located in nucleus. WB:WBGene00003601 nhr-2 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation; hormone-mediated signaling pathway; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including Cpaaaa; Cpaaap; Cpaapa; Cpaapp; and germ line. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); congenital nongoitrous hypothyroidism 6; and cystic fibrosis. Is an ortholog of human PPARA (peroxisome proliferator activated receptor alpha) and THRA (thyroid hormone receptor alpha). WB:WBGene00003602 nhr-3 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in hormone-mediated signaling pathway; regulation of transcription by RNA polymerase II; and tissue development. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Expressed in head neurons; hypodermis; muscle cell; and ventral nerve cord. WB:WBGene00003603 nhr-4 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in intestine; neurons; pharynx; and tail. WB:WBGene00003604 nhr-5 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003605 nhr-6 Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II; regulation of ovulation; and spermathecum morphogenesis. Located in nucleus. Expressed in BAGL; BAGR; chemosensory neurons; head neurons; and spermatheca. Human ortholog(s) of this gene implicated in Parkinson's disease and extraskeletal myxoid chondrosarcoma. Is an ortholog of human NR4A2 (nuclear receptor subfamily 4 group A member 2) and NR4A3 (nuclear receptor subfamily 4 group A member 3). WB:WBGene00003606 nhr-7 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation; hormone-mediated signaling pathway; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003607 nhr-8 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in cholesterol homeostasis. Located in nucleus. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); autosomal recessive limb-girdle muscular dystrophy type 2B; carcinoma (multiple); and lung disease (multiple). Is an ortholog of human VDR (vitamin D receptor). WB:WBGene00003608 nhr-9 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003609 nhr-10 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Part of chromatin. Expressed in intestine. WB:WBGene00003610 nhr-11 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003611 nhr-12 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003612 nhr-13 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in intestine. WB:WBGene00003613 nhr-14 Enables steroid hormone binding activity. Involved in defense response to Gram-negative bacterium; negative regulation of protein localization to nucleus; and regulation of innate immune response. Located in nucleus. Expressed in head and intestinal cell. WB:WBGene00003614 nhr-15 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head muscle and pharynx. WB:WBGene00003615 nhr-16 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003616 nhr-17 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in tail. WB:WBGene00003617 nhr-18 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in anal depressor muscle; intestinal muscle; and vulval muscle. WB:WBGene00003618 nhr-19 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003619 nhr-20 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head and tail. WB:WBGene00003620 nhr-21 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003621 nhr-22 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Located in cytosol and nucleus. Expressed in coelomocyte; hypodermis; intestine; neurons; and non-striated muscle. WB:WBGene00003622 nhr-23 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including defense response to Gram-negative bacterium; positive regulation of transcription by RNA polymerase II; and spermatogenesis. Located in nucleus. Part of chromatin. Expressed in several structures, including hypodermis; oocyte; spermatocyte; tail; and vulval precursor cell. Human ortholog(s) of this gene implicated in idiopathic generalized epilepsy 15 and immunodeficiency 42. Is an ortholog of human RORA (RAR related orphan receptor A); RORB (RAR related orphan receptor B); and RORC (RAR related orphan receptor C). WB:WBGene00003623 nhr-25 Enables armadillo repeat domain binding activity. Involved in molting cycle and positive regulation of nematode male tail tip morphogenesis. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including excretory system; gonad; hypodermal cell; tail; and vulval precursor cell. Human ortholog(s) of this gene implicated in several diseases, including Zellweger syndrome; gonadal dysgenesis (multiple); and primary ovarian insufficiency 7. Is an ortholog of human NR5A2 (nuclear receptor subfamily 5 group A member 2). WB:WBGene00003624 nhr-28 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in hypodermis; intestine; and pharynx. WB:WBGene00003625 nhr-31 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Involved in embryo development; post-embryonic animal morphogenesis; and response to osmotic stress. Predicted to be located in nucleus. Expressed in excretory cell. WB:WBGene00003626 nhr-32 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003627 nhr-34 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003628 nhr-35 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including Fanconi renotubular syndrome 4; glucose metabolism disease (multiple); and liver disease (multiple). Is an ortholog of human HNF4A (hepatocyte nuclear factor 4 alpha). WB:WBGene00003629 nhr-38 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in hormone-mediated signaling pathway; regulation of transcription by RNA polymerase II; and tissue development. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Expressed in AFDL and AFDR. WB:WBGene00003630 nhr-40 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including P1; P2; egg-laying apparatus; rectal gland cell; and somatic nervous system. WB:WBGene00003632 nhr-42 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in hypodermis; intestine; and pharynx. WB:WBGene00003633 nhr-43 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in dorsal nerve cord; excretory cell; head neurons; hypodermis; and intestine. WB:WBGene00003634 nhr-44 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head muscle; intestine; neurons; and pharynx. WB:WBGene00003635 nhr-45 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003636 nhr-46 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in several structures, including hypodermis; intestine; muscle cell; neurons; and spermatheca. WB:WBGene00003637 nhr-47 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head neurons; spermatheca; tail neurons; and ventral nerve cord. WB:WBGene00003638 nhr-48 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including anterior gonad arm; pharyngeal gland cell; and spermatheca. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); autosomal recessive limb-girdle muscular dystrophy type 2B; carcinoma (multiple); and lung disease (multiple). Is an ortholog of human VDR (vitamin D receptor). WB:WBGene00003639 nhr-49 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in determination of adult lifespan; positive regulation of transcription from RNA polymerase II promoter in response to stress; and regulation of fatty acid metabolic process. Located in cytoplasm and nucleus. Expressed in hypodermis; intestinal cell; intestine; muscle cell; and neurons. Used to study alcohol use disorder and obesity. Human ortholog(s) of this gene implicated in several diseases, including Fanconi renotubular syndrome 4; glucose metabolism disease (multiple); and liver disease (multiple). Is an ortholog of human HNF4A (hepatocyte nuclear factor 4 alpha). WB:WBGene00003640 nhr-50 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in ganglia; neurons; and tail. WB:WBGene00003641 nhr-51 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons; intestine; and tail neurons. WB:WBGene00003642 nhr-52 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons. WB:WBGene00003643 nhr-53 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003644 nhr-54 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons; intestine; pharynx; and tail neurons. WB:WBGene00003645 nhr-55 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003646 nhr-56 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in dorsal nerve cord; head neurons; intestine; tail neurons; and ventral nerve cord. WB:WBGene00003647 nhr-57 Predicted to enable DNA-binding transcription factor activity. Involved in response to hypoxia. Predicted to be located in nucleus. Expressed in several structures, including cephalic sheath cell; ciliated neurons; excretory system; intestine; and vulva. WB:WBGene00003648 nhr-58 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in excretory cell; excretory duct; excretory gland cell; and vulva. WB:WBGene00003649 nhr-59 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003650 nhr-60 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Located in nuclear envelope. Expressed in several structures, including VC neuron; pharyngeal gland cell; ray; seam cell; and uv1. WB:WBGene00003651 nhr-61 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003652 nhr-62 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in several structures, including excretory cell; intestine; neurons; spermatheca; and ventral nerve cord. WB:WBGene00003653 nhr-63 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in metacorpus; procorpus; terminal bulb; and vulva. WB:WBGene00003654 nhr-64 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in hypodermis; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including Fanconi renotubular syndrome 4; glucose metabolism disease (multiple); and liver disease (multiple). Is an ortholog of human HNF4A (hepatocyte nuclear factor 4 alpha) and HNF4G (hepatocyte nuclear factor 4 gamma). WB:WBGene00003655 nhr-65 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in several structures, including excretory cell; intestine; muscle cell; pharynx; and tail spike. WB:WBGene00003656 nhr-66 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in several structures, including head ganglion; hypodermis; neurons; terminal bulb; and ventral nerve cord. WB:WBGene00003657 nhr-67 Enables DNA-binding transcription factor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including gonad morphogenesis; negative regulation of G1/S transition of mitotic cell cycle; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including excretory cell; head ganglion; neurons; rectal valve cell; and vulval cell. Is an ortholog of human NR2E1 (nuclear receptor subfamily 2 group E member 1). WB:WBGene00003658 nhr-68 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Part of chromatin. Expressed in head muscle and head neurons. WB:WBGene00003659 nhr-69 Enables SMAD binding activity and steroid hormone binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including ASI; hypodermis; intestine; tail neurons; and uterine toroidal epithelial cell. Human ortholog(s) of this gene implicated in several diseases, including Fanconi renotubular syndrome 4; glucose metabolism disease (multiple); and liver disease (multiple). Is an ortholog of human HNF4A (hepatocyte nuclear factor 4 alpha) and HNF4G (hepatocyte nuclear factor 4 gamma). WB:WBGene00003660 nhr-70 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003661 nhr-71 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine; pharyngeal neurons; seam cell; and vulva. WB:WBGene00003662 nhr-72 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00003663 nhr-73 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00003664 nhr-74 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00003665 nhr-75 Expressed in seam cell. WB:WBGene00003667 nhr-77 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00003668 nhr-78 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003669 nhr-79 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in several structures, including Ealaa; Ealp; Earaa; amphid neurons; and intestine. WB:WBGene00003670 nhr-80 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Involved in determination of adult lifespan; positive regulation of metabolic process; and post-embryonic development. Located in nucleus. Expressed in head; intestine; muscle cell; somatic nervous system; and tail neurons. WB:WBGene00003671 nhr-81 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00003672 nhr-82 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00003673 nhr-83 Expressed in ganglia and neurons. WB:WBGene00003674 nhr-84 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in ganglia; intestine; and pharynx. WB:WBGene00003675 nhr-85 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation; hormone-mediated signaling pathway; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in excretory duct cell; hypodermis; rectal epithelium; and vulva. Human ortholog(s) of this gene implicated in several diseases, including alcoholic liver cirrhosis; brain small vessel disease; and type 2 diabetes mellitus. Is an ortholog of human NR1D1 (nuclear receptor subfamily 1 group D member 1) and NR1D2 (nuclear receptor subfamily 1 group D member 2). WB:WBGene00003676 nhr-86 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in hypodermis and pharynx. WB:WBGene00003677 nhr-87 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003678 nhr-88 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003679 nhr-89 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00003680 nhr-90 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in amphid neurons; intestine; and phasmid neurons. WB:WBGene00003681 nhr-91 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in anterior ganglion; excretory cell; seam cell; spermatheca; and vulva. Is an ortholog of human NR6A1 (nuclear receptor subfamily 6 group A member 1). WB:WBGene00003682 nhr-92 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003683 nhr-93 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003684 nhr-94 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003685 nhr-95 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003686 nhr-96 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003687 nhr-97 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003688 nhr-98 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in pharynx. WB:WBGene00003689 nhr-99 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003690 nhr-100 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003691 nhr-101 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003692 nhr-102 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003693 nhr-103 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003694 nhr-104 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003695 nhr-105 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003696 nhr-106 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003697 nhr-107 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003698 nhr-108 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head neurons; intestine; neurons; pharyngeal gland cell; and tail neurons. WB:WBGene00003699 nhr-109 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003700 nhr-110 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003701 nhr-111 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in PVD; head neurons; intestine; pharynx; and somatic gonad precursor. Human ortholog(s) of this gene implicated in enhanced S-cone syndrome and retinitis pigmentosa 37. Is an ortholog of human NR2E3 (nuclear receptor subfamily 2 group E member 3). WB:WBGene00003702 nhr-112 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in nucleus. Expressed in head and tail. WB:WBGene00003703 nhr-113 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00003704 nhr-114 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in regulation of gene expression. Acts upstream of with a positive effect on S-adenosylmethionine cycle. Located in nucleus. Expressed in germ line; hypodermis; and intestine. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human NR1H3 (nuclear receptor subfamily 1 group H member 3). WB:WBGene00003705 nhr-115 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Involved in innate immune response. Predicted to be located in nucleus. WB:WBGene00003706 nhr-116 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003707 nhr-117 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in terminal bulb. WB:WBGene00003708 nhr-118 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003709 nhr-119 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in hypodermis and intestine. WB:WBGene00003710 nhr-120 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003711 nhr-121 Enables steroid hormone binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003712 nhr-122 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003713 nhr-123 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in dorsal nerve cord; head neurons; intestine; pharynx; and ventral nerve cord. WB:WBGene00003714 nhr-124 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003715 nhr-125 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003716 nhr-126 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003717 nhr-127 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00003718 nhr-128 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003719 nhr-129 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003720 nhr-130 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003721 nhr-131 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in intestine and pharynx. WB:WBGene00003722 nhr-132 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in excretory cell and vulva. WB:WBGene00003723 nhr-133 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in several structures, including coelomocyte; excretory cell; neurons; rectal gland cell; and ventral nerve cord. WB:WBGene00003724 nhr-134 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003725 nhr-135 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00003726 nhr-136 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in response to starvation. Predicted to be located in nucleus. WB:WBGene00003727 nhr-137 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in membrane and nucleus. Expressed in neurons. WB:WBGene00003728 nhr-138 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00003729 nhx-1 Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to be located in plasma membrane. Expressed in AIYL; AIYR; hypodermis; intestine; and muscle cell. WB:WBGene00003730 nhx-2 Enables sodium:proton antiporter activity. Involved in several processes, including determination of adult lifespan; positive regulation of growth rate; and regulation of transport. Located in apical plasma membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive spinocerebellar ataxia 19; congenital secretory sodium diarrhea 8; and end stage renal disease. Is an ortholog of human SLC9A3 (solute carrier family 9 member A3) and SLC9A5 (solute carrier family 9 member A5). WB:WBGene00003731 nhx-3 Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to be located in plasma membrane. Expressed in epithelial cell; hypodermis; and spermathecal-uterine junction. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 8 and end stage renal disease. Is an ortholog of human SLC9A3 (solute carrier family 9 member A3) and SLC9A5 (solute carrier family 9 member A5). WB:WBGene00003732 nhx-4 Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to be located in plasma membrane. Expressed widely. WB:WBGene00003733 nhx-5 Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to be located in plasma membrane and recycling endosome. Expressed in several structures, including HSN; excretory cell; ganglia; ventral nerve cord; and vulC. Human ortholog(s) of this gene implicated in Christianson syndrome; X-linked intellectual developmental disorder 108; and autistic disorder. Is an ortholog of human SLC9A9 (solute carrier family 9 member A9). WB:WBGene00003734 nhx-6 Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to be located in plasma membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive spinocerebellar ataxia 19; congenital secretory sodium diarrhea 8; and end stage renal disease. Is an ortholog of human SLC9A2 (solute carrier family 9 member A2); SLC9A3 (solute carrier family 9 member A3); and SLC9A5 (solute carrier family 9 member A5). WB:WBGene00003735 nhx-8 Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport and regulation of intracellular pH. Predicted to be located in membrane. Expressed in several structures, including hypodermis; pharyngeal muscle cell; pharyngeal-intestinal valve; rectal valve cell; and vulva. Is an ortholog of human SLC9A8 (solute carrier family 9 member A8). WB:WBGene00003736 nhx-9 Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to be located in plasma membrane. Expressed in excretory cell; intestine; and phasmid sensillum. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 8 and end stage renal disease. Is an ortholog of human SLC9A3 (solute carrier family 9 member A3) and SLC9A5 (solute carrier family 9 member A5). WB:WBGene00003738 nid-1 An extracellular matrix structural constituent. Involved in several processes, including cholinergic synaptic transmission; nervous system development; and positive regulation of anterior/posterior axon guidance. Located in basal part of cell and basement membrane. Expressed in several structures, including enteric muscle; gonad; labial sensillum; neurons; and vulval cell. Is an ortholog of human NID1 (nidogen 1). WB:WBGene00003739 nlp-1 Involved in cellular response to carbon dioxide; negative regulation of pharyngeal pumping; and thigmotaxis. Expressed in intestine; lateral ganglion; and neurons. WB:WBGene00003740 nlp-2 Involved in embryo development and positive regulation of error-prone translesion synthesis. Expressed in AWAL; AWAR; head neurons; intestine; and uv1. WB:WBGene00003741 nlp-3 Predicted to be involved in neuropeptide signaling pathway. Expressed in alimentary muscle; intestine; neurons; oocyte; and vulva. WB:WBGene00003742 nlp-4 Predicted to be located in cell surface and extracellular region. WB:WBGene00003743 nlp-5 Predicted to be involved in neuropeptide signaling pathway. Expressed in nervous system and spermatheca. WB:WBGene00003744 nlp-6 Predicted to be involved in neuropeptide signaling pathway. Expressed in ASI; intestine; and neurons. WB:WBGene00003745 nlp-7 Involved in several processes, including determination of adult lifespan; positive regulation of egg-laying behavior; and response to caloric restriction. Expressed in egg-laying apparatus and nervous system. WB:WBGene00003746 nlp-8 Involved in sleep. Predicted to be located in extracellular region. Expressed in intestine; neurons; and pharynx. WB:WBGene00003747 nlp-9 Predicted to be involved in neuropeptide signaling pathway. Expressed in intestine; neurons; spermatheca; and vulval muscle. WB:WBGene00003748 nlp-10 Predicted to be involved in neuropeptide signaling pathway. Expressed in lateral ganglion; neurons; and in male. WB:WBGene00003749 nlp-11 Predicted to be involved in neuropeptide signaling pathway. Expressed in neurons. WB:WBGene00003750 nlp-12 Enables cholecystokinin receptor binding activity. Involved in foraging behavior and neuropeptide signaling pathway. Located in neuron projection and neuronal cell body. Expressed in DVA; PVDL; PVDR; coelomocyte; and tail neurons. WB:WBGene00003751 nlp-13 Predicted to be involved in neuropeptide signaling pathway. Expressed in several structures, including intestine; pharyngeal neurons; spermatheca; tail; and vulva. WB:WBGene00003752 nlp-14 Predicted to enable neuropeptide hormone activity. Involved in cellular response to carbon dioxide and negative regulation of pharyngeal pumping. Expressed in neurons and in male. WB:WBGene00003753 nlp-15 Predicted to enable neuropeptide hormone activity. Predicted to be involved in neuropeptide signaling pathway. Expressed in several structures, including XXX cell; intestine; neurons; pharynx; and vulva. WB:WBGene00003754 nlp-16 Expressed in head neurons; intestine; and lateral ganglion. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00003755 nlp-17 Predicted to be involved in neuropeptide signaling pathway. Expressed in PVQL; PVQR; and in male. WB:WBGene00003756 nlp-18 Predicted to be involved in neuropeptide signaling pathway. Expressed in intestine; neurons; rectal gland cell; and spermatheca. WB:WBGene00003757 nlp-19 Predicted to be involved in neuropeptide signaling pathway. Expressed in head neurons; pharyngeal neurons; spermatheca; and ventral nerve cord. WB:WBGene00003758 nlp-20 Predicted to be involved in neuropeptide signaling pathway. Expressed in head neurons; intestine; pharyngeal neurons; spermatheca; and tail neurons. WB:WBGene00003759 nlp-21 Predicted to be involved in neuropeptide signaling pathway. Expressed in body wall musculature; dorsal nerve cord; intestine; and neurons. WB:WBGene00003760 nlp-22 Involved in embryo development and positive regulation of error-prone translesion synthesis. Expressed in RIAL; RIAR; head; and ventral nerve cord. WB:WBGene00003761 nlp-23 Predicted to be involved in neuropeptide signaling pathway. Expressed in hypodermis and tail. WB:WBGene00003762 nlp-24 Predicted to be involved in neuropeptide signaling pathway. Expressed in ASIL; ASIR; hypodermis; pharyngeal neurons; and spermatheca. WB:WBGene00003763 nlp-25 Predicted to be involved in neuropeptide signaling pathway. Expressed in embryonic cell. WB:WBGene00003764 nlp-26 Predicted to be involved in neuropeptide signaling pathway. Expressed in several structures, including P2.p; P3.pa; P3.pp; P4.pa; and P4.pp. WB:WBGene00003765 nlp-27 Involved in defense response to Gram-negative bacterium. Predicted to be located in membrane. Expressed in ASI; head neurons; hypodermis; intestine; and spermatheca. WB:WBGene00003766 nlp-28 Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in extracellular region. WB:WBGene00003767 nlp-29 Predicted to enable neuropeptide receptor binding activity. Predicted to be involved in defense response to other organism; killing of cells of another organism; and neuropeptide signaling pathway. Predicted to be located in extracellular space. Expressed in hyp7 syncytium; hypodermis; and intestine. WB:WBGene00003768 nlp-30 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in hypodermis. WB:WBGene00003769 nlp-31 Enables double-stranded DNA binding activity. Involved in defense response to Gram-negative bacterium; defense response to fungus; and killing of cells of another organism. Predicted to be located in extracellular region. Expressed in hypodermis. WB:WBGene00003770 nlp-32 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in head. WB:WBGene00003771 nlp-33 Involved in defense response to fungus and innate immune response. Predicted to be located in extracellular region. WB:WBGene00003772 nlr-1 Enables actin filament binding activity and gap junction channel activity. Involved in positive regulation of gap junction assembly and positive regulation of pharyngeal pumping. Located in gap junction. Expressed in RIS; pharyngeal gland cell; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Pitt-Hopkins syndrome; autistic disorder; and communication disorder (multiple). Is an ortholog of human CNTNAP5 (contactin associated protein family member 5). WB:WBGene00003773 nlt-1 Predicted to enable lipid binding activity. Predicted to be located in cytosol. Is an ortholog of human SCP2D1 (SCP2 sterol binding domain containing 1). WB:WBGene00003774 nmr-1 Predicted to enable ligand-gated monoatomic ion channel activity and signaling receptor activity. Predicted to contribute to NMDA glutamate receptor activity. Involved in locomotory behavior and regulation of forward locomotion. Located in neuron projection; plasma membrane; and synapse. Expressed in ganglia; gonadal sheath cell; head mesodermal cell; nerve ring neurons; and oocyte. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; alcohol use disorder; autosomal dominant intellectual developmental disorder 8; and developmental and epileptic encephalopathy 101. Is an ortholog of human GRIN1 (glutamate ionotropic receptor NMDA type subunit 1). WB:WBGene00003775 nmr-2 Predicted to enable NMDA glutamate receptor activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Predicted to be located in postsynaptic density membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Huntington's disease; epilepsy (multiple); and gastrointestinal system cancer (multiple). Is an ortholog of human GRIN2C (glutamate ionotropic receptor NMDA type subunit 2C). WB:WBGene00003776 nmy-1 Predicted to enable actin filament binding activity and microfilament motor activity. Involved in several processes, including nematode larval development; protein localization; and regulation of embryonic cell shape. Located in adherens junction and contractile fiber. Expressed in head; hypodermis; and tail. Human ortholog(s) of this gene implicated in several diseases, including aortic aneurysm (multiple); auditory system disease (multiple); and blood platelet disease (multiple). Is an ortholog of human MYH11 (myosin heavy chain 11). WB:WBGene00003777 nmy-2 Enables calmodulin binding activity and protein kinase binding activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; cell division; and regulation of anatomical structure morphogenesis. Located in several cellular components, including cleavage furrow; contractile ring; and mitotic spindle. Expressed in several structures, including distal tip cell; germ line; hypodermal cell; neuroblasts; and rectal gland cell. Human ortholog(s) of this gene implicated in several diseases, including aortic aneurysm (multiple); auditory system disease (multiple); and blood platelet disease (multiple). Is an ortholog of human MYH10 (myosin heavy chain 10); MYH11 (myosin heavy chain 11); and MYH9 (myosin heavy chain 9). WB:WBGene00003778 nnt-1 Predicted to enable NAD(P)+ transhydrogenase activity and NADP binding activity. Predicted to be involved in NADPH regeneration. Located in mitochondrion. Expressed in ganglia; intestine; pharyngeal-intestinal valve; and somatic nervous system. Human ortholog(s) of this gene implicated in familial glucocorticoid deficiency. Is an ortholog of human NNT (nicotinamide nucleotide transhydrogenase). WB:WBGene00003779 nob-1 Enables sequence-specific DNA binding activity. Involved in several processes, including nematode male tail tip morphogenesis; pattern specification process; and positive regulation of nematode male tail tip morphogenesis. Located in nucleus. Expressed in head muscle; intestine; linker cell; somatic nervous system; and tail. Is an ortholog of several human genes including HOXA9 (homeobox A9); HOXB9 (homeobox B9); and HOXC10 (homeobox C10). WB:WBGene00003780 nob-3 No description available WB:WBGene00003783 nos-1 Predicted to enable mRNA binding activity. Involved in medium-term memory and short-term memory. Predicted to be located in perinuclear region of cytoplasm. Expressed in Z2 and Z3. Human ortholog(s) of this gene implicated in spermatogenic failure 12. Is an ortholog of human NANOS1 (nanos C2HC-type zinc finger 1); NANOS2 (nanos C2HC-type zinc finger 2); and NANOS3 (nanos C2HC-type zinc finger 3). WB:WBGene00003784 nos-2 Predicted to enable mRNA binding activity and zinc ion binding activity. Involved in oogenesis and regulation of cell cycle. Located in cytoplasm. Expressed in P0; P4; Z2; and Z3. Human ortholog(s) of this gene implicated in spermatogenic failure 12. Is an ortholog of human NANOS1 (nanos C2HC-type zinc finger 1); NANOS2 (nanos C2HC-type zinc finger 2); and NANOS3 (nanos C2HC-type zinc finger 3). WB:WBGene00003785 nos-3 Predicted to enable RNA binding activity. Involved in positive regulation of meiotic nuclear division. Located in cytoplasm. Expressed in several structures, including Psub3; Psub4; Z2; Z3; and germ line. WB:WBGene00003786 npa-1 Enriched in PVP; RIF; head mesodermal cell; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on proteomic; microarray; and RNA-seq studies. Is affected by twenty-three chemicals including Astaxanthin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Nematode polyprotein allergen ABA-1; Polyprotein allergen, nematode; and DVA-1 superfamily. WB:WBGene00003787 npp-1 Enables calmodulin binding activity. Involved in several processes, including organelle organization; positive regulation of mitotic cell cycle, embryonic; and regulation of asymmetric cell division. Located in nuclear envelope. Expressed in several structures, including hypodermis. Human ortholog(s) of this gene implicated in dystonia. Is an ortholog of human NUP54 (nucleoporin 54). WB:WBGene00003788 npp-2 Predicted to be a structural constituent of nuclear pore. Involved in embryo development; nucleus organization; and protein localization to organelle. Part of nuclear pore. Human ortholog(s) of this gene implicated in nephrotic syndrome type 17. Is an ortholog of human NUP85 (nucleoporin 85). WB:WBGene00003789 npp-3 Predicted to be a structural constituent of nuclear pore. Involved in several processes, including establishment of localization in cell; positive regulation of nematode male tail tip morphogenesis; and regulation of cell cycle. Predicted to be located in nucleus. Predicted to be part of nuclear pore inner ring. Expressed in embryonic cell. Human ortholog(s) of this gene implicated in nephrotic syndrome type 13. Is an ortholog of human NUP205 (nucleoporin 205). WB:WBGene00003790 npp-4 Predicted to enable phospholipid binding activity. Predicted to be a structural constituent of nuclear pore. Involved in determination of adult lifespan; embryo development; and organelle organization. Predicted to be part of nuclear pore central transport channel. WB:WBGene00003791 npp-5 Predicted to be a structural constituent of nuclear pore. Involved in several processes, including kinetochore assembly; protein localization to kinetochore; and regulation of nucleus size. Located in nuclear membrane. Part of nuclear pore. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome; nephrotic syndrome type 11; and ovarian dysgenesis 6. Is an ortholog of human NUP107 (nucleoporin 107). WB:WBGene00003792 npp-6 Predicted to be a structural constituent of nuclear pore. Involved in several processes, including nucleus organization; positive regulation of nematode male tail tip morphogenesis; and protein localization to organelle. Located in nuclear membrane. Part of nuclear pore. Human ortholog(s) of this gene implicated in nephrotic syndrome type 19. Is an ortholog of human NUP160 (nucleoporin 160). WB:WBGene00003793 npp-7 Predicted to enable nuclear localization sequence binding activity. Predicted to be a structural constituent of nuclear pore. Involved in several processes, including determination of adult lifespan; nucleus organization; and regulation of exit from mitosis. Located in nuclear membrane. Part of nuclear pore. Is an ortholog of human POM121 (POM121 transmembrane nucleoporin) and POM121C (POM121 transmembrane nucleoporin C). WB:WBGene00003794 npp-8 Predicted to be a structural constituent of nuclear pore. Involved in embryo development; nucleus organization; and regulation of exit from mitosis. Part of nuclear pore. Human ortholog(s) of this gene implicated in familial atrial fibrillation. Is an ortholog of human NUP155 (nucleoporin 155). WB:WBGene00003795 npp-9 Predicted to enable metal ion binding activity. Predicted to contribute to GTPase activator activity. Involved in embryo development and nucleus organization. Part of nuclear pore. Human ortholog(s) of this gene implicated in brain disease; inflammatory myofibroblastic tumor; and multiple myeloma. Is an ortholog of human RANBP2 (RAN binding protein 2). WB:WBGene00003796 npp-10 Enables RNA binding activity. Involved in embryo development; organelle organization; and protein localization to organelle. Located in P granule; kinetochore; and nuclear envelope. Part of nuclear pore. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia. Is an ortholog of human NUP98 (nucleoporin 98 and 96 precursor). WB:WBGene00003797 npp-11 Predicted to enable phospholipid binding activity. Predicted to be a structural constituent of nuclear pore. Involved in embryo development; establishment of mitotic spindle orientation; and nucleus organization. Located in nuclear envelope. Expressed in head. Human ortholog(s) of this gene implicated in primary biliary cholangitis and striatonigral degeneration. Is an ortholog of human NUP62 (nucleoporin 62) and NUP62CL (nucleoporin 62 C-terminal like). WB:WBGene00003798 npp-12 Part of nuclear pore. Is an ortholog of human NUP210 (nucleoporin 210) and NUP210L (nucleoporin 210 like). WB:WBGene00003799 npp-13 Predicted to be a structural constituent of nuclear pore. Involved in several processes, including organelle organization; protein import into nucleus; and regulation of cell cycle. Predicted to be located in membrane and nucleus. Predicted to be part of nuclear pore. Human ortholog(s) of this gene implicated in nephrotic syndrome type 12. Is an ortholog of human NUP93 (nucleoporin 93). WB:WBGene00003800 npp-14 Enables caspase binding activity. Involved in negative regulation of execution phase of apoptosis. Predicted to be located in nuclear membrane. Predicted to be part of nuclear pore. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; acute myeloid leukemia; and brain disease. Is an ortholog of human NUP214 (nucleoporin 214). WB:WBGene00003801 npp-15 Predicted to be a structural constituent of nuclear pore. Predicted to be involved in poly(A)+ mRNA export from nucleus; protein import into nucleus; and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Located in kinetochore and nuclear membrane. Part of nuclear pore. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome and nephrotic syndrome type 18. Is an ortholog of human NUP133 (nucleoporin 133). WB:WBGene00003802 npp-16 Predicted to be involved in protein import into nucleus. Predicted to be located in nuclear membrane. Predicted to be part of nuclear pore. Is an ortholog of human NUP50 (nucleoporin 50). WB:WBGene00003803 rae-1 Predicted to enable RNA binding activity and ubiquitin binding activity. Predicted to be involved in RNA export from nucleus and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to be located in axon; nucleus; and synapse. Predicted to be part of nuclear pore. Is an ortholog of human RAE1 (ribonucleic acid export 1). WB:WBGene00003804 npp-18 Predicted to enable structural molecule activity. Predicted to be involved in cellular response to amino acid starvation and positive regulation of TORC1 signaling. Predicted to be located in lysosomal membrane and nuclear envelope. Predicted to be part of Seh1-associated complex and nuclear pore outer ring. Is an ortholog of human SEH1L (SEH1 like nucleoporin). WB:WBGene00003805 npp-19 Predicted to enable phospholipid binding activity. Predicted to be a structural constituent of nuclear pore. Involved in embryo development; nucleus organization; and regulation of exit from mitosis. Located in nuclear envelope. Part of nuclear pore. Is an ortholog of human NUP35 (nucleoporin 35). WB:WBGene00003806 npp-20 Predicted to enable structural molecule activity. Involved in several processes, including organelle organization; positive regulation of division septum assembly; and protein import into nucleus. Part of nuclear pore. Is an ortholog of human SEC13 (SEC13 homolog, nuclear pore and COPII coat complex component). WB:WBGene00003807 npr-1 Enables neuropeptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; behavioral response to ethanol; and thermotaxis. Located in axon; plasma membrane; and somatodendritic compartment. Expressed in excretory system; neurons; pharyngeal muscle cell; and preanal ganglion. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in hypertension. Is an ortholog of human PRLHR (prolactin releasing hormone receptor). WB:WBGene00003808 npr-2 Predicted to enable neuropeptide binding activity and neuropeptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection and plasma membrane. Expressed in head neurons and interneuron. WB:WBGene00003809 nrf-1 No description available WB:WBGene00003810 nrf-3 No description available WB:WBGene00003811 nrf-4 No description available WB:WBGene00003812 nrf-5 Enables phosphatidylserine binding activity. Involved in lipid transport and positive regulation of engulfment of apoptotic cell. Located in extracellular region. Expressed in apoptotic cell; body wall musculature; intestine; and pharyngeal cell. WB:WBGene00003813 nrf-6 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups and lipid binding activity. Predicted to be involved in lipid transport. Predicted to be located in membrane. Expressed in hyp3; hyp5; and intestine. WB:WBGene00003814 nrf-8 No description available WB:WBGene00003815 nars-1 Predicted to enable asparagine-tRNA ligase activity. Involved in translation. Predicted to be located in cytoplasm. Is an ortholog of human NARS1 (asparaginyl-tRNA synthetase 1). WB:WBGene00003816 asns-1 Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity. Predicted to be involved in asparagine biosynthetic process. Predicted to be located in cytosol. Is an ortholog of human ASNS (asparagine synthetase (glutamine-hydrolyzing)). WB:WBGene00003818 nsf-1 Predicted to enable ATP hydrolysis activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in Golgi stack. Expressed in several structures, including egg-laying apparatus; excretory gland cell; intestinal cell; pharynx; and rectal gland cell. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 96. Is an ortholog of human NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase). WB:WBGene00003821 nst-1 Predicted to enable GTP binding activity. Involved in germ cell development; nematode larval development; and regulation of growth. Located in nucleolus and nucleoplasm. Expressed widely. Used to study obesity. Is an ortholog of human GNL3L (G protein nucleolar 3 like). WB:WBGene00003822 nsy-1 Enables MAP kinase kinase kinase activity; mitogen-activated protein kinase kinase binding activity; and protein serine/threonine/tyrosine kinase activity. Involved in several processes, including defense response to other organism; determination of adult lifespan; and egg-laying behavior. Located in axon cytoplasm; neuronal cell body; and postsynaptic density. Expressed in head; rectal gland cell; and tail. Used to study amphetamine abuse. Human ortholog(s) of this gene implicated in Huntington's disease and perinatal necrotizing enterocolitis. Is an ortholog of human MAP3K5 (mitogen-activated protein kinase kinase kinase 5). WB:WBGene00003825 ntl-2 Predicted to be involved in regulation of DNA-templated transcription and regulation of stem cell population maintenance. Predicted to be part of CCR4-NOT core complex. Is an ortholog of human CNOT2 (CCR4-NOT transcription complex subunit 2). WB:WBGene00003826 ntl-3 Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in P-body. Predicted to be part of CCR4-NOT core complex. Is an ortholog of human CNOT3 (CCR4-NOT transcription complex subunit 3). WB:WBGene00003827 ntl-4 Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be part of CCR4-NOT complex. Is an ortholog of human CNOT4 (CCR4-NOT transcription complex subunit 4). WB:WBGene00003828 nuc-1 Enables deoxyribonuclease II activity. Involved in apoptotic DNA fragmentation. Acts upstream of or within with a positive effect on negative regulation of antimicrobial peptide production. Located in lysosome. Expressed in body wall musculature; head; intestinal cell; and vulva. Is an ortholog of human DNASE2 (deoxyribonuclease 2, lysosomal) and DNASE2B (deoxyribonuclease 2 beta). WB:WBGene00003829 nud-1 Enables identical protein binding activity and unfolded protein binding activity. Involved in several processes, including GABAergic synaptic transmission; establishment of organelle localization; and vulval development. Predicted to be located in cytoplasm. Expressed in gonad; hypodermis; intestine; and neurons. Used to study epilepsy and lissencephaly. Is an ortholog of human NUDC (nuclear distribution C, dynein complex regulator). WB:WBGene00003830 num-1 Enables enzyme binding activity and protein domain specific binding activity. Involved in endocytic recycling; phospholipid transport; and protein targeting to membrane. Located in basolateral plasma membrane and cytoplasm. Expressed in several structures, including alimentary muscle; hermaphrodite gonad; nerve ring; pseudocoelom; and rectal valve cell. Is an ortholog of human NUMB (NUMB endocytic adaptor protein) and NUMBL (NUMB like endocytic adaptor protein). WB:WBGene00003831 nuo-1 Predicted to enable several functions, including 4 iron, 4 sulfur cluster binding activity; NADH dehydrogenase (ubiquinone) activity; and nucleotide binding activity. Involved in several processes, including dauer exit; determination of adult lifespan; and inductive cell migration. Located in mitochondrion. Used to study mitochondrial complex I deficiency. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 4. Is an ortholog of human NDUFV1 (NADH:ubiquinone oxidoreductase core subunit V1). WB:WBGene00003832 nup-1 No description available WB:WBGene00003833 nup-2 No description available WB:WBGene00003834 nxf-1 Predicted to enable RNA binding activity. Predicted to be involved in mRNA export from nucleus. Located in nuclear envelope; nucleolus; and nucleoplasm. Part of nuclear pore. Is an ortholog of human NXF1 (nuclear RNA export factor 1); NXF2 (nuclear RNA export factor 2); and NXF2B (nuclear RNA export factor 2B). WB:WBGene00003835 nxf-2 Predicted to enable RNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to be located in nucleus. Expressed in germ cell. Is an ortholog of several human genes including NXF1 (nuclear RNA export factor 1); NXF2 (nuclear RNA export factor 2); and NXF3 (nuclear RNA export factor 3). WB:WBGene00003836 nxt-1 Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nuclear pore central transport channel. Is an ortholog of human NXT1 (nuclear transport factor 2 like export factor 1) and NXT2 (nuclear transport factor 2 like export factor 2). WB:WBGene00003837 oat-1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Is an ortholog of several human genes including SLC22A17 (solute carrier family 22 member 17); SLC22A6 (solute carrier family 22 member 6); and SLC22A8 (solute carrier family 22 member 8). WB:WBGene00003838 ocr-1 Enables temperature-gated cation channel activity. Involved in heat acclimation. Predicted to be located in membrane. Expressed in ADLL; ADLR; AWAL; and AWAR. Human ortholog(s) of this gene implicated in several diseases, including keratosis (multiple); migraine with aura; and rosacea. Is an ortholog of human TRPV5 (transient receptor potential cation channel subfamily V member 5) and TRPV6 (transient receptor potential cation channel subfamily V member 6). WB:WBGene00003839 ocr-2 Enables temperature-gated cation channel activity. Involved in heat acclimation. Located in non-motile cilium and plasma membrane. Expressed in several structures, including SMDVL; body ganglion; head neurons; lumbar neurons; and uterus. Human ortholog(s) of this gene implicated in several diseases, including keratosis (multiple); motor neuron disease (multiple); and osteochondrodysplasia (multiple). Is an ortholog of human TRPV5 (transient receptor potential cation channel subfamily V member 5). WB:WBGene00003840 ocr-3 Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Expressed in rectal gland cell and socket cell. Human ortholog(s) of this gene implicated in hyperparathyroidism. Is an ortholog of human TRPV5 (transient receptor potential cation channel subfamily V member 5) and TRPV6 (transient receptor potential cation channel subfamily V member 6). WB:WBGene00003841 ocr-4 Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Expressed in OLQDL; OLQDR; OLQVL; OLQVR; and uv1. Human ortholog(s) of this gene implicated in several diseases, including keratosis (multiple); motor neuron disease (multiple); and osteochondrodysplasia (multiple). Is an ortholog of human TRPV5 (transient receptor potential cation channel subfamily V member 5) and TRPV6 (transient receptor potential cation channel subfamily V member 6). WB:WBGene00003842 oct-1 Enables organic cation transmembrane transporter activity. Involved in determination of adult lifespan and organic cation transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including myelodysplastic syndrome; rheumatoid arthritis; and systemic primary carnitine deficiency disease. Is an ortholog of human SLC22A4 (solute carrier family 22 member 4). WB:WBGene00003843 oct-2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC22A15 (solute carrier family 22 member 15). WB:WBGene00003844 odc-1 Enables ornithine decarboxylase activity. Involved in putrescine biosynthetic process from ornithine. Predicted to be located in cytoplasm. Expressed in intestine and male gonad. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and liver cirrhosis. Is an ortholog of human AZIN1 (antizyme inhibitor 1); AZIN2 (antizyme inhibitor 2); and ODC1 (ornithine decarboxylase 1). WB:WBGene00003845 odd-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine. Is an ortholog of human OSR1 (odd-skipped related transcription factor 1) and OSR2 (odd-skipped related transciption factor 2). WB:WBGene00003846 odd-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine. Is an ortholog of human OSR1 (odd-skipped related transcription factor 1) and OSR2 (odd-skipped related transciption factor 2). WB:WBGene00003847 blmp-1 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of distal tip cell migration; regulation of developmental process; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Expressed in several structures, including distal tip cell; dorsal nerve cord; enteric muscle; neurons; and tail hypodermis. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung adenocarcinoma; and non-Hodgkin lymphoma (multiple). Is an ortholog of human PRDM1 (PR/SET domain 1). WB:WBGene00003848 odr-1 Predicted to enable ATP binding activity; guanylate cyclase activity; and protein kinase activity. Predicted to be involved in cGMP biosynthetic process and intracellular signal transduction. Predicted to be located in membrane. Expressed in I1 neuron and amphid neurons. Human ortholog(s) of this gene implicated in congenital diarrhea 6. Is an ortholog of human GUCY2C (guanylate cyclase 2C). WB:WBGene00003849 odr-2 Involved in olfactory behavior and response to odorant. Located in axon; external side of plasma membrane; and neuronal cell body. Expressed in head neurons; sensory neurons; somatic nervous system; tail; and in male. WB:WBGene00003850 odr-3 Enables olfactory receptor binding activity. Involved in several processes, including hyperosmotic response; olfactory behavior; and response to odorant. Located in neuronal cell body and non-motile cilium. Expressed in amphid neurons. WB:WBGene00003851 odr-4 Involved in olfactory behavior; receptor localization to non-motile cilium; and response to odorant. Located in intracellular membrane-bounded organelle and protein-containing complex. Expressed in chemosensory neurons and neurons. Is an ortholog of human ODR4 (odr-4 GPCR localization factor homolog). WB:WBGene00003852 odr-5 No description available WB:WBGene00003853 odr-6 No description available WB:WBGene00003854 odr-7 Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in negative adaptation of signaling pathway; positive chemotaxis; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in AWAL and AWAR. WB:WBGene00003856 odr-10 Enables G protein-coupled olfactory receptor activity and G-protein alpha-subunit binding activity. Involved in several processes, including detection of chemical stimulus involved in sensory perception; olfactory behavior; and positive chemotaxis. Located in non-motile cilium; periciliary membrane compartment; and somatodendritic compartment. Expressed in AWAL; AWAR; and in male. WB:WBGene00003857 ogr-1 No description available WB:WBGene00003858 ogt-1 Enables protein N-acetylglucosaminyltransferase activity; protein O-acetylglucosaminyltransferase activity; and protein serine/threonine phosphatase activity. Involved in several processes, including dauer larval development; glycogen metabolic process; and lipid storage. Located in nucleus and perinuclear region of cytoplasm. Expressed in several structures, including hypodermal cell; intestine; neurons; and somatic cell. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in aortic valve stenosis and non-syndromic X-linked intellectual disability 106. Is an ortholog of human OGT (O-linked N-acetylglucosamine (GlcNAc) transferase). WB:WBGene00003859 oig-1 Predicted to be involved in nervous system development. Predicted to be located in extracellular space; membrane; and neuron projection. Expressed in neurons. WB:WBGene00003860 oig-2 Predicted to be involved in axon guidance and cell adhesion. Located in sarcoplasmic reticulum. Expressed in several structures, including midbody; neurons; pharynx; tail; and ventral nerve cord. WB:WBGene00003861 oig-3 Expressed in PVT; gonad; gonadal sheath cell; and pharynx. Is predicted to encode a protein with the following domains: Immunoglobulin-like fold; Immunoglobulin-like domain superfamily; Immunoglobulin I-set; Phosphorylation site; and Immunoglobulin I-set domain. WB:WBGene00003862 old-1 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in hypodermis; male gonad; neurons; and pharynx. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); and prostate cancer. Is an ortholog of human FLT3 (fms related receptor tyrosine kinase 3). WB:WBGene00003863 old-2 Predicted to enable transmembrane receptor protein tyrosine kinase activator activity and transmembrane receptor protein tyrosine kinase activity. Involved in determination of adult lifespan. Predicted to be located in membrane. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); and prostate cancer. Is an ortholog of human FLT3 (fms related receptor tyrosine kinase 3). WB:WBGene00003864 oma-1 Enables mRNA 3'-UTR AU-rich region binding activity and mRNA regulatory element binding translation repressor activity. Involved in several processes, including negative regulation of cell differentiation; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Part of messenger ribonucleoprotein complex. Expressed in several structures, including head muscle; neurons; oocyte; somatic nervous system; and vulva. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00003865 oma-2 Enables mRNA regulatory element binding translation repressor activity. Involved in several processes, including meiotic nuclear membrane disassembly; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Expressed in several structures, including germ line; head muscle; intestine; oocyte; and somatic nervous system. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00003866 ooc-1 Acts upstream of or within embryo development. WB:WBGene00003867 ooc-2 No description available WB:WBGene00003868 ooc-3 Predicted to enable chloride channel activity. Involved in embryo development; establishment of mitotic spindle orientation; and protein localization. Located in endoplasmic reticulum. Expressed in P0. WB:WBGene00003869 ooc-4 No description available WB:WBGene00003870 ooc-5 Predicted to enable ATP binding activity and ATP hydrolysis activity. Involved in cellular response to misfolded protein. Located in several cellular components, including endoplasmic reticulum; perinuclear region of cytoplasm; and spindle. Expressed in several structures, including CAN; intestine; pharyngeal-intestinal valve; pharynx; and rectal gland cell. Used to study torsion dystonia 1. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-5 and torsion dystonia 1. Is an ortholog of human TOR1A (torsin family 1 member A) and TOR1B (torsin family 1 member B). WB:WBGene00003876 pept-2 Predicted to enable dipeptide transmembrane transporter activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in membrane. Expressed in anal depressor muscle; anal sphincter muscle; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human SLC15A1 (solute carrier family 15 member 1). WB:WBGene00003877 pept-1 Enables dipeptide transmembrane transporter activity. Involved in several processes, including chemical homeostasis; nitrogen compound transport; and regulation of signal transduction. Located in apical plasma membrane. Expressed in intestine. Used to study obesity. Is an ortholog of human SLC15A1 (solute carrier family 15 member 1). WB:WBGene00003878 pept-3 Enables dipeptide transmembrane transporter activity and proton channel activity. Involved in dipeptide transport and proton transmembrane transport. Predicted to be located in membrane. Expressed in AVAL; AVAR; pharynx; and touch receptor neurons. Is an ortholog of human SLC15A1 (solute carrier family 15 member 1) and SLC15A2 (solute carrier family 15 member 2). WB:WBGene00003879 ora-1 Enriched in several structures, including ABplapaaaa; BDU; cholinergic neurons; posterior arcade cell; and touch receptor neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00003880 ora-2 No description available WB:WBGene00003881 ora-4 No description available WB:WBGene00003882 orc-2 Predicted to enable DNA replication origin binding activity. Predicted to be involved in DNA replication. Located in nuclear chromosome. Is an ortholog of human ORC2 (origin recognition complex subunit 2). WB:WBGene00003883 osm-1 Involved in dauer entry and non-motile cilium assembly. Located in ciliary transition zone and non-motile cilium. Part of intraciliary transport particle B. Expressed in amphid neurons; ciliated neurons; phasmid neurons; and sensory neurons. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 20; retinitis pigmentosa 71; and short-rib thoracic dysplasia 10 with or without polydactyly. Is an ortholog of human IFT172 (intraflagellar transport 172). WB:WBGene00003884 osm-3 Enables plus-end-directed microtubule motor activity. Involved in several processes, including cilium organization; dauer entry; and regulation of non-motile cilium assembly. Located in neuronal cell body; perinuclear region of cytoplasm; and plasma membrane bounded cell projection. Part of kinesin complex. Expressed in ciliated neurons. Is an ortholog of human KIF17 (kinesin family member 17). WB:WBGene00003885 osm-5 Predicted to enable kinesin binding activity. Involved in several processes, including dauer entry; locomotory exploration behavior; and non-motile cilium assembly. Located in ciliary basal body; neuron projection; and non-motile cilium. Part of intraciliary transport particle B. Expressed in amphid sensillum and neurons. Used to study autosomal dominant polycystic kidney disease. Is an ortholog of human IFT88 (intraflagellar transport 88). WB:WBGene00003886 osm-6 Involved in several processes, including non-motile cilium assembly; response to osmotic stress; and sensory perception of mechanical stimulus. Located in cilium; cytoplasm; and neuronal cell body. Expressed in neurons. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Is an ortholog of human IFT52 (intraflagellar transport 52). WB:WBGene00003887 osm-7 Predicted to enable Notch binding activity. Involved in regulation of gene expression and response to osmotic stress. Predicted to be located in extracellular space. Expressed in hypodermis. WB:WBGene00003888 osm-8 Involved in regulation of gene expression and response to osmotic stress. Located in extracellular space. Expressed in hyp7 syncytium. WB:WBGene00003889 osm-9 Enables calcium channel activity and temperature-gated cation channel activity. Involved in several processes, including heat acclimation; negative adaptation of signaling pathway; and nervous system process. Located in neuronal cell body; non-motile cilium; and perinuclear region of cytoplasm. Expressed in RIG; head mesodermal cell; rectal gland cell; sensory neurons; and uterine toroidal epithelial cell. Human ortholog(s) of this gene implicated in several diseases, including keratosis (multiple); motor neuron disease (multiple); and osteochondrodysplasia (multiple). Is an ortholog of human TRPV3 (transient receptor potential cation channel subfamily V member 3); TRPV4 (transient receptor potential cation channel subfamily V member 4); and TRPV5 (transient receptor potential cation channel subfamily V member 5). WB:WBGene00003890 osm-10 Enables osmosensor activity. Involved in osmosensory signaling pathway. Located in axon; cytoplasm; and neuronal cell body. WB:WBGene00003891 osm-11 Enables Notch binding activity. Involved in several processes, including positive regulation of Notch signaling pathway; response to osmotic stress; and vulval development. Located in apical part of cell and extracellular space. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and hermaphrodite gonad. WB:WBGene00003892 osm-12 Involved in chemotaxis; cilium organization; and protein localization to microvillus membrane. Located in ciliary basal body; neuron projection; and non-motile cilium. Expressed in ciliated neurons and sensory neurons. Used to study Bardet-Biedl syndrome. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 7. Is an ortholog of human BBS7 (Bardet-Biedl syndrome 7). WB:WBGene00003893 ost-1 Enables calcium ion binding activity. Located in basement membrane and extracellular space. Expressed in body wall musculature; gonad; head; pharynx; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); osteogenesis imperfecta type 17; and progressive osseous heteroplasia. Is an ortholog of human SPARC (secreted protein acidic and cysteine rich). WB:WBGene00003898 oxi-1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Human ortholog(s) of this gene implicated in Kaufman oculocerebrofacial syndrome. Is an ortholog of human UBE3B (ubiquitin protein ligase E3B). WB:WBGene00003899 oxy-2 No description available WB:WBGene00003900 oxy-3 No description available WB:WBGene00003901 paa-1 Enables DEAD/H-box RNA helicase binding activity. Involved in embryo development. Located in P granule; microtubule cytoskeleton; and nuclear envelope. Part of protein phosphatase type 2A complex. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 36. Is an ortholog of human PPP2R1A (protein phosphatase 2 scaffold subunit Aalpha) and PPP2R1B (protein phosphatase 2 scaffold subunit Abeta). WB:WBGene00003902 pab-1 Enables mRNA binding activity. Involved in several processes, including gamete generation; positive regulation of reproductive process; and regulation of cell cycle. Located in P granule and P-body. Part of polysome. Expressed in intestine. Is an ortholog of several human genes including PABPC1 (poly(A) binding protein cytoplasmic 1); PABPC3 (poly(A) binding protein cytoplasmic 3); and PABPC4 (poly(A) binding protein cytoplasmic 4). WB:WBGene00003903 pab-2 Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Part of polysome. Is an ortholog of human PABPC1 (poly(A) binding protein cytoplasmic 1) and PABPC3 (poly(A) binding protein cytoplasmic 3). WB:WBGene00003904 pabp-2 Predicted to enable poly(A) binding activity. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in oculopharyngeal muscular dystrophy. Is an ortholog of human PABPN1 (poly(A) binding protein nuclear 1). WB:WBGene00003905 pad-1 Predicted to be involved in Golgi to endosome transport and protein transport. Predicted to be located in endosome and trans-Golgi network. Expressed in head and tail. Used to study Down syndrome. Is an ortholog of human DOP1A (DOP1 leucine zipper like protein A) and DOP1B (DOP1 leucine zipper like protein B). WB:WBGene00003906 paf-1 Enables 1-alkyl-2-acetylglycerophosphocholine esterase activity. Involved in lipid catabolic process. Predicted to be located in cytosol and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and glomerulonephritis (multiple). Is an ortholog of human PAFAH2 (platelet activating factor acetylhydrolase 2) and PLA2G7 (phospholipase A2 group VII). WB:WBGene00003907 paf-2 Enables 1-alkyl-2-acetylglycerophosphocholine esterase activity. Involved in lipid catabolic process and morphogenesis of embryonic epithelium. Predicted to be located in cytosol and endoplasmic reticulum membrane. Expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and glomerulonephritis (multiple). Is an ortholog of human PAFAH2 (platelet activating factor acetylhydrolase 2) and PLA2G7 (phospholipase A2 group VII). WB:WBGene00003908 pag-1 No description available WB:WBGene00003909 pag-3 Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; transcription corepressor activity; and transcription corepressor binding activity. Involved in several processes, including negative regulation of secretion by cell; neuroblast fate specification; and regulation of locomotion. Located in nucleus. Expressed in several structures, including P1.aap; P11.aaap; P12.aaap; neurons; and retrovesicular ganglion. Used to study alcohol use disorder. Is an ortholog of human ZNF683 (zinc finger protein 683). WB:WBGene00003910 pag-6 No description available WB:WBGene00003911 pak-1 Enables GTP binding activity and protein kinase activity. Involved in several processes, including anatomical structure morphogenesis; hemidesmosome assembly; and inductive cell migration. Located in several cellular components, including axon; hemidesmosome; and neuronal cell body. Expressed in several structures, including P5.p hermaphrodite; P7.p hermaphrodite; gonad; hypodermis; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); kidney cancer (multiple); and non-syndromic X-linked intellectual disability 30. Is an ortholog of human PAK1 (p21 (RAC1) activated kinase 1); PAK2 (p21 (RAC1) activated kinase 2); and PAK3 (p21 (RAC1) activated kinase 3). WB:WBGene00003912 pal-1 Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell fate commitment; embryonic pattern specification; and positive regulation of RNA metabolic process. Located in condensed nuclear chromosome. Expressed in several structures, including ABprpppppaa; enteric muscle; epithelial cell; oocyte; and tail spike. Human ortholog(s) of this gene implicated in Barrett's esophagus. Is an ortholog of human CDX1 (caudal type homeobox 1) and CDX2 (caudal type homeobox 2). WB:WBGene00003913 pal-2 No description available WB:WBGene00003914 pam-1 Enables metalloaminopeptidase activity. Involved in several processes, including exit from meiosis; first cell cycle pseudocleavage; and regulation of reproductive process. Located in condensed chromosome; cytoplasm; and mitotic spindle pole. Expressed in amphid process; intestine; male-specific anatomical entity; nerve ring; and tail neurons. Is an ortholog of human NPEPPS (aminopeptidase puromycin sensitive). WB:WBGene00003915 pan-1 Enables DEAD/H-box RNA helicase binding activity. Involved in germ cell development and molting cycle. Located in P granule and plasma membrane. Expressed in several structures, including germ line; gonad; head muscle; somatic cell; and somatic nervous system. WB:WBGene00003916 par-1 Enables myosin II tail binding activity; protein serine/threonine kinase activity; and ubiquitin protein ligase binding activity. Involved in several processes, including cell fate commitment; embryonic pattern specification; and vulval development. Located in P granule and cell cortex. Expressed in germ line and vulva. Human ortholog(s) of this gene implicated in visual impairment and progressive phthisis bulbi. Is an ortholog of human MARK1 (microtubule affinity regulating kinase 1). WB:WBGene00003917 par-2 Enables microtubule binding activity; phosphatidylinositol phosphate binding activity; and protein kinase binding activity. Involved in asymmetric cell division; asymmetric protein localization involved in cell fate determination; and establishment of mitotic spindle orientation. Located in P granule; posterior cell cortex; and protein-containing complex. Expressed in germ line. WB:WBGene00003918 par-3 Predicted to enable phosphatidylinositol binding activity. Involved in several processes, including establishment of mitotic spindle orientation; gonad development; and polarity specification of anterior/posterior axis. Located in several cellular components, including P granule; basal part of cell; and cell cortex. Is extrinsic component of cytoplasmic side of plasma membrane. Expressed in several structures, including AB; Psub1; excretory cell; hermaphrodite gonad; and vulval cell. Is an ortholog of human PARD3B (par-3 family cell polarity regulator beta). WB:WBGene00003919 par-4 Enables calmodulin binding activity and protein serine/threonine kinase activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; cell division; and determination of adult lifespan. Located in cell cortex. Expressed widely. Used to study Peutz-Jeghers syndrome. Human ortholog(s) of this gene implicated in several diseases, including Peutz-Jeghers syndrome; familial melanoma; and female reproductive organ cancer (multiple). Is an ortholog of human STK11 (serine/threonine kinase 11). WB:WBGene00003920 par-5 Involved in several processes, including cellular localization; determination of adult lifespan; and first cell cycle pseudocleavage. Located in cell cortex and nucleus. Expressed in head neurons. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ovarian cancer; and urinary bladder cancer. Is an ortholog of human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) and YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). WB:WBGene00003921 par-6 Enables protein kinase C binding activity and small GTPase binding activity. Involved in several processes, including establishment of mitotic spindle localization; gonad development; and polarity specification of anterior/posterior axis. Located in P granule and cell cortex. Is extrinsic component of cytoplasmic side of plasma membrane. Expressed in several structures, including ABa; EMS; Psub2; Psub3; and excretory cell. Is an ortholog of human PARD6B (par-6 family cell polarity regulator beta). WB:WBGene00003922 pas-1 Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Human ortholog(s) of this gene implicated in myocardial infarction. Is an ortholog of human PSMA6 (proteasome 20S subunit alpha 6). WB:WBGene00003923 pas-2 Enables identical protein binding activity. Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Is an ortholog of human PSMA2 (proteasome 20S subunit alpha 2). WB:WBGene00003924 pas-3 Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Is an ortholog of human PSMA4 (proteasome 20S subunit alpha 4). WB:WBGene00003925 pas-4 Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Expressed in tail. Is an ortholog of human PSMA7 (proteasome 20S subunit alpha 7) and PSMA8 (proteasome 20S subunit alpha 8). WB:WBGene00003926 pas-5 Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Expressed in body wall musculature; germ line; gonad; hypodermis; and vulva. Is an ortholog of human PSMA5 (proteasome 20S subunit alpha 5). WB:WBGene00003927 pas-6 Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Is an ortholog of human PSMA1 (proteasome 20S subunit alpha 1). WB:WBGene00003928 pas-7 Enables identical protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Located in cytoplasm and nucleus. Is an ortholog of human PSMA3 (proteasome 20S subunit alpha 3). WB:WBGene00003929 pat-2 Enables transmembrane signaling receptor activity. Involved in several processes, including muscle cell cellular homeostasis; positive regulation of cellular component organization; and regulation of locomotion. Located in M band; cell surface; and striated muscle dense body. Expressed in body wall musculature; distal tip cell; hypodermis; and touch receptor neurons. Human ortholog(s) of this gene implicated in several diseases, including abdominal aortic aneurysm; blood platelet disease (multiple); and von Willebrand's disease (multiple). Is an ortholog of several human genes including ITGA2B (integrin subunit alpha 2b); ITGA5 (integrin subunit alpha 5); and ITGAV (integrin subunit alpha V). WB:WBGene00003930 pat-3 Predicted to enable integrin binding activity. Involved in several processes, including muscle cell cellular homeostasis; positive regulation of cellular component organization; and regulation of locomotion. Located in several cellular components, including contractile fiber; focal adhesion; and lateral plasma membrane. Part of integrin complex. Expressed in several structures, including GABAergic neurons; egg-laying apparatus; enteric muscle; gonad; and vulval precursor cell. Used to study cancer. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); and lung carcinoma (multiple). Is an ortholog of human ITGB1 (integrin subunit beta 1). WB:WBGene00003931 pat-4 Enables integrin binding activity and protein-macromolecule adaptor activity. Involved in several processes, including integrin-mediated signaling pathway; organelle organization; and positive regulation of supramolecular fiber organization. Located in adherens junction; basal plasma membrane; and contractile fiber. Part of integrin complex. Expressed in body wall musculature; gonad; non-striated muscle; pharynx; and touch receptor neurons. Human ortholog(s) of this gene implicated in ovarian cancer; pancreatic cancer; and prostate adenocarcinoma. Is an ortholog of human ILK (integrin linked kinase). WB:WBGene00003932 pat-6 Predicted to enable actin binding activity. Involved in several processes, including muscle cell cellular homeostasis; positive regulation of sarcomere organization; and striated muscle cell development. Located in M band; basal plasma membrane; and striated muscle dense body. Expressed in body wall musculature; gonad; non-striated muscle; and touch receptor neurons. Is an ortholog of human PARVA (parvin alpha). WB:WBGene00003933 pat-9 Predicted to enable chromatin insulator sequence binding activity. Involved in regulation of striated muscle cell differentiation. Located in nucleus. Expressed in body wall musculature and gonad. WB:WBGene00003934 pat-10 Enables troponin I binding activity. Involved in embryo development; muscle contraction; and skeletal muscle thin filament assembly. Located in contractile fiber. Expressed in body wall musculature; gonadal sheath cell; rectal muscle; and vulval muscle. Is an ortholog of human CALML6 (calmodulin like 6). WB:WBGene00003935 pat-11 No description available WB:WBGene00003936 pat-12 Involved in embryonic morphogenesis and hemidesmosome assembly. Located in hemidesmosome. Expressed in head neurons; mechanosensory neurons; rectum; seam cell; and spermatheca. WB:WBGene00003937 pax-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to Gram-negative bacterium. Located in nucleus. Expressed in epithelial cell and pharyngeal cell. Human ortholog(s) of this gene implicated in branchiootorenal syndrome and tooth agenesis. Is an ortholog of human PAX9 (paired box 9). WB:WBGene00003938 pax-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome and nucleus. Expressed in vulD. Human ortholog(s) of this gene implicated in several diseases, including congenital nongoitrous hypothyroidism 2; focal segmental glomerulosclerosis 7; and renal Wilms' tumor. Is an ortholog of human PAX2 (paired box 2); PAX5 (paired box 5); and PAX8 (paired box 8). WB:WBGene00003939 pax-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in epidermal cell fate specification; gonad morphogenesis; and hemidesmosome assembly. Located in nucleus. Expressed in several structures, including AB lineage cell; E lineage cell; P9/10L; hypodermal cell; and tail. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma and congenital myopathy 19. Is an ortholog of human PAX7 (paired box 7). WB:WBGene00003940 pbm-1 No description available WB:WBGene00003941 pbo-1 Predicted to enable calcium ion binding activity. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in spastic ataxia. Is an ortholog of human CHP1 (calcineurin like EF-hand protein 1) and CHP2 (calcineurin like EF-hand protein 2). WB:WBGene00003942 pbo-3 No description available WB:WBGene00003943 pbo-4 Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Involved in several processes, including defecation; lipid transport involved in lipid storage; and positive regulation of multicellular organismal process. Located in basolateral plasma membrane. Expressed in intestine. WB:WBGene00003946 pbo-7 No description available WB:WBGene00003947 pbs-1 Predicted to enable endopeptidase activity. Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; autoimmune disease (multiple); and carcinoma (multiple). Is an ortholog of human PSMB9 (proteasome 20S subunit beta 9). WB:WBGene00003948 pbs-2 Predicted to enable endopeptidase activity. Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Is an ortholog of human PSMB7 (proteasome 20S subunit beta 7). WB:WBGene00003949 pbs-3 Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Is an ortholog of human PSMB3 (proteasome 20S subunit beta 3). WB:WBGene00003950 pbs-4 Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Is an ortholog of human PSMB2 (proteasome 20S subunit beta 2). WB:WBGene00003951 pbs-5 Predicted to enable endopeptidase activity. Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Human ortholog(s) of this gene implicated in JMP syndrome. Is an ortholog of human PSMB5 (proteasome 20S subunit beta 5). WB:WBGene00003952 pbs-6 Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Expressed in pharynx. Is an ortholog of human PSMB1 (proteasome 20S subunit beta 1). WB:WBGene00003953 pbs-7 Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Is an ortholog of human PSMB4 (proteasome 20S subunit beta 4). WB:WBGene00003954 pcm-1 Enables protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. Involved in multicellular organismal response to stress; regulation of autophagy; and response to starvation. Located in axon; cytosol; and neuronal cell body. Expressed in several structures, including alimentary muscle; dorso-rectal ganglion; gonad; somatic nervous system; and vulval muscle. Human ortholog(s) of this gene implicated in Alzheimer's disease and malignant astrocytoma. Is an ortholog of human PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase). WB:WBGene00003955 pcn-1 Enables DNA polymerase binding activity. Predicted to be involved in leading strand elongation; mismatch repair; and translesion synthesis. Predicted to be located in nucleus. Predicted to be part of PCNA complex. Human ortholog(s) of this gene implicated in several diseases, including Lewy body dementia; invasive ductal carcinoma; and kidney cancer (multiple). Is an ortholog of human PCNA (proliferating cell nuclear antigen). WB:WBGene00003956 pcp-1 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human PRCP (prolylcarboxypeptidase). WB:WBGene00003957 pcp-2 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. Is an ortholog of human PRSS16 (serine protease 16). WB:WBGene00003958 pcp-3 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. Is an ortholog of human PRSS16 (serine protease 16). WB:WBGene00003959 pcp-4 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. Is an ortholog of human PRSS16 (serine protease 16). WB:WBGene00003960 pcs-1 Enables glutathione gamma-glutamylcysteinyltransferase activity. Involved in phytochelatin biosynthetic process and response to metal ion. Expressed in several structures, including coelomocyte; non-striated muscle; pharyngeal-intestinal valve; pharynx; and rectal valve cell. WB:WBGene00003961 pct-1 Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in regulation of transcription involved in G1/S transition of mitotic cell cycle. Located in axon and dendrite. Is an ortholog of human CDK16 (cyclin dependent kinase 16). WB:WBGene00003962 pdi-1 Enables protein disulfide isomerase activity and protein-glutamine gamma-glutamyltransferase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum. Expressed in hypodermis. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Is an ortholog of human P4HB (prolyl 4-hydroxylase subunit beta). WB:WBGene00003963 pdi-2 Enables protein disulfide isomerase activity and protein-glutamine gamma-glutamyltransferase activity. Contributes to peptidyl-proline 4-dioxygenase activity. Involved in macromolecule modification and obsolete oxidation-reduction process. Located in endoplasmic reticulum. Part of procollagen-proline 4-dioxygenase complex. Expressed in several structures, including germ line and hypodermis. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Is an ortholog of human P4HB (prolyl 4-hydroxylase subunit beta). WB:WBGene00003964 pdi-3 Enables protein disulfide isomerase activity and protein-glutamine gamma-glutamyltransferase activity. Involved in several processes, including collagen and cuticulin-based cuticle development; egg-laying behavior; and male anatomical structure morphogenesis. Predicted to be located in endoplasmic reticulum. Expressed in hypodermis; intestine; and seam cell. Human ortholog(s) of this gene implicated in autoimmune hepatitis and liver cirrhosis. Is an ortholog of human PDIA3 (protein disulfide isomerase family A member 3). WB:WBGene00003965 pdk-1 Enables protein kinase activity. Involved in several processes, including cellular response to reactive oxygen species; dauer larval development; and regulation of synaptic assembly at neuromuscular junction. Located in axon; neuronal cell body; and nucleus. Expressed in several structures, including gonad; intestine; neurons; pharynx; and ventral nerve cord. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and prostate cancer. Is an ortholog of human PDPK1 (3-phosphoinositide dependent protein kinase 1). WB:WBGene00003966 pdl-1 Predicted to be involved in sensory perception of light stimulus. Predicted to be located in cytoplasm. Expressed in oxygen sensory neurons. Human ortholog(s) of this gene implicated in Joubert syndrome 22. Is an ortholog of human PDE6D (phosphodiesterase 6D). WB:WBGene00003967 pdr-1 Enables ubiquitin conjugating enzyme binding activity. Contributes to ubiquitin-protein transferase activity. Involved in several processes, including determination of adult lifespan; negative regulation of engulfment of apoptotic cell; and protein metabolic process. Located in mitochondrial outer membrane and neuronal cell body. Part of ubiquitin ligase complex. Expressed in muscle cell and neurons. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; Parkinson's disease 2; and female reproductive organ cancer (multiple). Is an ortholog of human PRKN (parkin RBR E3 ubiquitin protein ligase). WB:WBGene00003968 peb-1 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including germ line; hypodermis; pharyngeal cell; pharyngeal-intestinal valve; and rectal epithelial cell. WB:WBGene00003969 pef-1 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in detection of stimulus involved in sensory perception. Located in neuronal cell body. Expressed in hypodermis; intestinal cell; muscle cell; and neurons. Is an ortholog of human PPEF1 (protein phosphatase with EF-hand domain 1). WB:WBGene00003970 pek-1 Enables eukaryotic translation initiation factor 2alpha kinase activity. Involved in several processes, including PERK-mediated unfolded protein response; nematode larval development; and positive regulation of protein phosphorylation. Predicted to be located in endoplasmic reticulum membrane and nucleus. Expressed in intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in Wolcott-Rallison syndrome and type 1 diabetes mellitus. Is an ortholog of human EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3). WB:WBGene00003971 pel-1 No description available WB:WBGene00003972 pel-2 No description available WB:WBGene00003973 pel-3 No description available WB:WBGene00003974 pel-4 No description available WB:WBGene00003975 pen-2 Involved in several processes, including Notch signaling pathway; cell differentiation; and pharynx development. Located in membrane. Expressed in intestine; muscle cell; neurons; and vulva. Human ortholog(s) of this gene implicated in hidradenitis suppurativa. Is an ortholog of human PSENEN (presenilin enhancer, gamma-secretase subunit). WB:WBGene00003976 pes-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryo development and nematode larval development. Located in cytoplasm and nucleus. Expressed in several structures, including ABplaaaap; ABplaaapa; body wall muscle cell from D lineage; neurons; and somatic gonad precursor. WB:WBGene00003977 pes-2.1 Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including hydrogen sulfide; methylmercuric chloride; and mianserin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00003978 pes-4 Predicted to enable mRNA binding activity. Predicted to be involved in regulation of RNA metabolic process and regulation of gene expression. Predicted to be located in cytoplasm and nucleus. Expressed in rectal epithelium. Is an ortholog of several human genes including PCBP1 (poly(rC) binding protein 1); PCBP2 (poly(rC) binding protein 2); and PCBP3 (poly(rC) binding protein 3). WB:WBGene00003979 pes-5 Predicted to be located in membrane. WB:WBGene00003980 pes-7 Predicted to enable GTPase activator activity; actin filament binding activity; and calmodulin binding activity. Predicted to be involved in mitotic actomyosin contractile ring assembly actin filament organization. Predicted to be located in cell cortex. Expressed in ganglia; intestine; muscle cell; and tail. Is an ortholog of human IQGAP1 (IQ motif containing GTPase activating protein 1); IQGAP2 (IQ motif containing GTPase activating protein 2); and IQGAP3 (IQ motif containing GTPase activating protein 3). WB:WBGene00003981 pes-8 Predicted to be located in membrane. Expressed in hermaphrodite gonad and rectum. WB:WBGene00003982 pes-9 Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human CNDP2 (carnosine dipeptidase 2). WB:WBGene00003983 pes-10 Located in cytoplasm and nucleus. WB:WBGene00003984 pes-11 No description available WB:WBGene00003985 pes-12 No description available WB:WBGene00003986 mct-4 Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 7 and lymphangioleiomyomatosis. Is an ortholog of several human genes including SLC16A1 (solute carrier family 16 member 1); SLC16A7 (solute carrier family 16 member 7); and SLC16A8 (solute carrier family 16 member 8). WB:WBGene00003987 pes-23 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00003988 pex-3 No description available WB:WBGene00003989 pfn-1 Predicted to enable actin monomer binding activity. Predicted to be involved in sequestering of actin monomers. Predicted to be located in cell cortex. Expressed in gonadal sheath cell; nerve ring; neurons; spermatheca; and vulva. WB:WBGene00003990 pfn-2 Predicted to enable actin monomer binding activity. Involved in muscle thin filament assembly. Predicted to be located in cell cortex. Expressed in pharynx and spermatheca. WB:WBGene00003991 pfn-3 Predicted to enable actin monomer binding activity. Involved in muscle thin filament assembly. Located in striated muscle dense body. Expressed in body wall musculature. WB:WBGene00003992 pgl-1 Enables RNA endonuclease activity; identical protein binding activity; and protein self-association. Involved in P granule organization and germ-line stem cell division. Located in P granule. Expressed in germ line. WB:WBGene00003993 pgl-2 Predicted to be involved in oogenesis. Located in P granule. Expressed in germ line. WB:WBGene00003994 pgl-3 Enables RNA endonuclease activity and identical protein binding activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis and obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. Located in P granule. Expressed in Psub1 and germ line. WB:WBGene00003995 pgp-1 Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Involved in defense response to other organism; response to metal ion; and response to nematicide. Located in apical plasma membrane. Expressed in intestinal cell; intestine; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of human ABCB1 (ATP binding cassette subfamily B member 1); ABCB4 (ATP binding cassette subfamily B member 4); and ABCB5 (ATP binding cassette subfamily B member 5). WB:WBGene00003996 pgp-2 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in gut granule assembly and lipid storage. Located in gut granule membrane. Expressed in AWAL and AWAR. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of human ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4). WB:WBGene00003997 pgp-3 Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Involved in defense response to Gram-negative bacterium; innate immune response; and stress response to cadmium ion. Located in apical plasma membrane. Expressed in excretory canal; excretory cell; intestinal cell; intestine; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of several human genes including ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4). WB:WBGene00003998 pgp-4 Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing and stress response to cadmium ion. Predicted to be located in plasma membrane. Expressed in excretory canal. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of several human genes including ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4). WB:WBGene00003999 pgp-5 Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Involved in several processes, including defense response to bacterium; response to nematicide; and stress response to metal ion. Predicted to be located in plasma membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human ABCB1 (ATP binding cassette subfamily B member 1) and ABCB4 (ATP binding cassette subfamily B member 4). WB:WBGene00004000 pgp-6 Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Involved in response to nematicide. Predicted to be located in plasma membrane. Expressed in amphid neurons and head. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of several human genes including ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4). WB:WBGene00004001 pgp-7 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in stress response to cadmium ion. Predicted to be located in membrane. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of several human genes including ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4). WB:WBGene00004002 pgp-8 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in head neurons. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of several human genes including ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4). WB:WBGene00004003 pgp-9 Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of human ABCB1 (ATP binding cassette subfamily B member 1); ABCB4 (ATP binding cassette subfamily B member 4); and ABCB5 (ATP binding cassette subfamily B member 5). WB:WBGene00004004 pgp-10 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00004005 pgp-11 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be located in membrane. WB:WBGene00004006 pgp-12 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in response to nematicide. Predicted to be located in membrane. Expressed in head and tail. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of several human genes including ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4). WB:WBGene00004007 pgp-13 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in amphid neurons and intestine. WB:WBGene00004008 pgp-14 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in response to nematicide. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human ABCB1 (ATP binding cassette subfamily B member 1); ABCB4 (ATP binding cassette subfamily B member 4); and ABCB5 (ATP binding cassette subfamily B member 5). WB:WBGene00004009 pgp-15 Expressed in head neurons and tail neurons. WB:WBGene00004010 pha-1 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Involved in embryonic digestive tract morphogenesis; nematode larval development; and reproduction. Located in cytoplasm. Expressed in body wall muscle cell and pharynx. WB:WBGene00004011 pha-2 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including eating behavior; muscle structure development; and pharyngeal gland morphogenesis. Located in nucleus. Expressed in head neurons; intestine; pharynx; and rectal gland cell. Is an ortholog of human HHEX (hematopoietically expressed homeobox). WB:WBGene00004012 pha-3 Acts upstream of or within pharynx development. WB:WBGene00004013 pha-4 Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; pharynx development; and positive regulation of metabolic process. Located in nucleus. Expressed in several structures, including arcade cell; enteric muscle; gonad; pharynx; and rectum. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); lung carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human FOXA1 (forkhead box A1) and FOXA2 (forkhead box A2). WB:WBGene00004014 phb-1 Involved in several processes, including defecation; developmental process involved in reproduction; and mitochondrion morphogenesis. Located in mitochondrial membrane. Part of mitochondrial prohibitin complex. Expressed in several structures, including body wall musculature; excretory canal; hypodermis; intestine; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including cervix uteri carcinoma in situ; prostate carcinoma in situ; and sporadic breast cancer. Is an ortholog of human PHB1 (prohibitin 1). WB:WBGene00004015 phb-2 Predicted to enable protein homodimerization activity. Involved in several processes, including defecation; developmental process involved in reproduction; and mitochondrion organization. Located in mitochondrial membrane. Part of mitochondrial prohibitin complex. Expressed in body wall musculature; excretory canal; hypodermis; intestine; and neurons. Is an ortholog of human PHB2 (prohibitin 2). WB:WBGene00004016 phf-5 Predicted to be involved in mRNA splicing, via spliceosome. Located in cytoplasm and nucleus. Expressed in body wall musculature; intestine; pharyngeal muscle cell; pharynx; and rectal muscle. Is an ortholog of human PHF5A (PHD finger protein 5A). WB:WBGene00004017 phg-1 Involved in negative regulation of cell cycle G1/S phase transition. Located in plasma membrane. Expressed in muscle cell and pharynx. WB:WBGene00004019 phm-3 No description available WB:WBGene00004020 pho-1 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Located in membrane raft. Expressed in intestine. Used to study obesity. WB:WBGene00004021 pho-2 No description available WB:WBGene00004022 pho-3 No description available WB:WBGene00004023 pho-4 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00004024 php-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of nematode male tail tip morphogenesis. Predicted to be located in nucleus. Expressed in several structures, including coelomocyte; head neurons; intestine; somatic nervous system; and tail neurons. Human ortholog(s) of this gene implicated in congenital vertical talus. Is an ortholog of human HOXC10 (homeobox C10). WB:WBGene00004025 phy-2 Enables peptidyl-proline 4-dioxygenase activity. Involved in macromolecule modification and obsolete oxidation-reduction process. Located in endoplasmic reticulum. Expressed in excretory cell; hypodermis; and spermatheca. Human ortholog(s) of this gene implicated in myopia. Is an ortholog of human P4HA1 (prolyl 4-hydroxylase subunit alpha 1). WB:WBGene00004026 phy-3 Predicted to enable procollagen-proline 4-dioxygenase activity. Predicted to be located in endoplasmic reticulum. Expressed in spermatheca. WB:WBGene00004027 pie-1 Predicted to enable mRNA 3'-UTR binding activity. Involved in several processes, including embryonic pattern specification; formation of primary germ layer; and negative regulation of nitrogen compound metabolic process. Located in several cellular components, including P granule; centrosome; and cytosol. Expressed in germ line; head muscle; and nerve ring. WB:WBGene00004028 pif-1 Predicted to enable 5'-3' DNA helicase activity. Predicted to be involved in DNA duplex unwinding and DNA replication. Predicted to be located in replication fork. Is an ortholog of human PIF1 (PIF1 5'-to-3' DNA helicase). WB:WBGene00004029 pik-1 Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in cellular response to lipopolysaccharide and signal transduction. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Expressed in RMGL; RMGR; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of musculoskeletal system (multiple); diffuse scleroderma; and melioidosis. Is an ortholog of human IRAK1 (interleukin 1 receptor associated kinase 1). WB:WBGene00004030 pin-2 Predicted to enable metal ion binding activity. Predicted to be involved in several processes, including cell-cell junction organization; positive regulation of integrin-mediated signaling pathway; and positive regulation of substrate adhesion-dependent cell spreading. Located in cytoplasm; nucleus; and varicosity. Expressed in PVT. WB:WBGene00004031 pis-1 Involved in programmed cell death. Part of MLL3/4 complex. Is an ortholog of human PAXIP1 (PAX interacting protein 1). WB:WBGene00004032 pkc-1 Enables protein kinase C activity. Involved in several processes, including nervous system process; regulation of presynaptic dense core granule exocytosis; and signaling. Located in cholinergic synapse and neuron projection. Expressed in ganglia; linker cell; and neurons. Human ortholog(s) of this gene implicated in cerebral infarction. Is an ortholog of human PRKCE (protein kinase C epsilon). WB:WBGene00004033 pkc-2 Enables calcium-dependent protein kinase C activity and protein serine kinase activity. Predicted to be involved in intracellular signal transduction. Located in several cellular components, including cytosol; neuron projection; and neuronal cell body. Expressed in body wall musculature; intestine; neurons; somatic nervous system; and tail ganglion. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; brain disease (multiple); carcinoma (multiple); and ductal carcinoma in situ. Is an ortholog of human PRKCA (protein kinase C alpha) and PRKCB (protein kinase C beta). WB:WBGene00004034 pkc-3 Enables protein domain specific binding activity and protein serine/threonine kinase activity. Involved in several processes, including antifungal innate immune response; gonad development; and response to wounding. Located in apical plasma membrane; cortical actin cytoskeleton; and cytosol. Expressed in several structures, including Psub4; enteric muscle; hypodermis; pharyngeal-intestinal valve; and vulva. Human ortholog(s) of this gene implicated in invasive ductal carcinoma and ovarian carcinoma. Is an ortholog of human PRKCI (protein kinase C iota) and PRKCZ (protein kinase C zeta). WB:WBGene00004035 pkd-2 Enables calcium channel activity. Involved in calcium ion transport; response to hermaphrodite contact; and vulval location. Located in several cellular components, including neuronal cell body; perinuclear region of cytoplasm; and plasma membrane bounded cell projection. Expressed in CEM; nerve ring; neurons; and ray. Used to study autosomal dominant polycystic kidney disease. Human ortholog(s) of this gene implicated in intracranial aneurysm; polycystic kidney disease 2; and retinal degeneration. Is an ortholog of human PKD2 (polycystin 2, transient receptor potential cation channel) and PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel). WB:WBGene00004036 plc-1 Enables GTPase inhibitor activity; phosphatidylinositol phospholipase C activity; and small GTPase binding activity. Involved in several processes, including 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process; defense response to Gram-positive bacterium; and positive regulation of protein import into nucleus. Expressed in excretory system; intestine; neurons; spermatheca; and vulva. Human ortholog(s) of this gene implicated in gastric adenocarcinoma; nephrotic syndrome type 2; and nephrotic syndrome type 3. Is an ortholog of human PLCE1 (phospholipase C epsilon 1). WB:WBGene00004037 plc-2 Predicted to enable phosphatidylinositol phospholipase C activity. Predicted to be involved in phosphatidylinositol-mediated signaling and release of sequestered calcium ion into cytosol. WB:WBGene00004038 plc-3 Predicted to enable phosphatidylinositol phospholipase C activity. Involved in sleep. Expressed in ALA; gonad; intestine; and non-striated muscle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); familial adenomatous polyposis; and familial cold autoinflammatory syndrome 3. Is an ortholog of human PLCG2 (phospholipase C gamma 2). WB:WBGene00004039 plc-4 Predicted to enable phosphatidylinositol phospholipase C activity. Predicted to be involved in phosphatidylinositol-mediated signaling and release of sequestered calcium ion into cytosol. Expressed in vas deferens. Human ortholog(s) of this gene implicated in Alzheimer's disease; nonsyndromic congenital nail disorder 3; and spermatogenic failure 17. Is an ortholog of human PLCD3 (phospholipase C delta 3). WB:WBGene00004040 pld-1 Predicted to enable phospholipase D activity. Predicted to be involved in phospholipid catabolic process and regulation of vesicle-mediated transport. Predicted to be located in intracellular membrane-bounded organelle. Expressed in tail. Human ortholog(s) of this gene implicated in developmental cardiac valvular defect; pancreatic ductal adenocarcinoma; and renal cell carcinoma. Is an ortholog of human PLD1 (phospholipase D1). WB:WBGene00004041 plg-1 Expressed in vas deferens and in male. WB:WBGene00004042 plk-1 Enables protein serine/threonine kinase activity. Involved in organelle organization; positive regulation of nematode male tail tip morphogenesis; and regulation of cell cycle. Located in several cellular components, including condensed chromosome; microtubule cytoskeleton; and nucleus. Expressed in AB and embryonic cell. Human ortholog(s) of this gene implicated in several diseases, including breast carcinoma; reproductive organ cancer (multiple); and urinary bladder cancer. Is an ortholog of human PLK1 (polo like kinase 1). WB:WBGene00004043 plk-2 Predicted to enable protein serine/threonine kinase activity. Involved in regulation of meiosis I. Located in cytoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including breast carcinoma; reproductive organ cancer (multiple); and urinary bladder cancer. Is an ortholog of human PLK1 (polo like kinase 1). WB:WBGene00004044 plk-3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mitotic spindle organization. Predicted to be located in several cellular components, including kinetochore; microtubule cytoskeleton; and nucleus. Human ortholog(s) of this gene implicated in several diseases, including breast carcinoma; reproductive organ cancer (multiple); and urinary bladder cancer. Is an ortholog of human PLK1 (polo like kinase 1). WB:WBGene00004045 pll-1 Predicted to enable phosphatidylinositol phospholipase C activity. Predicted to be involved in intracellular signal transduction and lipid catabolic process. Expressed in AIYL and AIYR. Is an ortholog of human PLCL1 (phospholipase C like 1 (inactive)) and PLCL2 (phospholipase C like 2). WB:WBGene00004046 plp-1 Enables double-stranded telomeric DNA binding activity. Involved in germ cell development and regulation of locomotion. Located in P granule and nucleus. Expressed in several structures, including Caa; Cpa; Psub4; oocyte; and somatic cell. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 31. Is an ortholog of human PURB (purine rich element binding protein B). WB:WBGene00004047 plx-1 Enables semaphorin receptor activity. Involved in epidermis development; nematode male tail mating organ morphogenesis; and nematode male tail tip morphogenesis. Located in ruffle membrane. Expressed in several structures, including DA9; epithelial cell; non-striated muscle; somatic nervous system; and tail. Is an ortholog of several human genes including PLXNA1 (plexin A1); PLXNA2 (plexin A2); and PLXNA3 (plexin A3). WB:WBGene00004048 plx-2 Enables semaphorin receptor activity. Involved in several processes, including axonal fasciculation; nematode male tail tip morphogenesis; and regulation of axon guidance. Located in cell leading edge and cell surface. Expressed in several structures, including P3/4L; P9/10L; P9/10R; neuroblasts; and ray structural cell. WB:WBGene00004049 parp-1 Enables NAD+ ADP-ribosyltransferase activity. Involved in determination of adult lifespan. Predicted to be located in nucleolus. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; idiopathic pulmonary fibrosis; and perinatal necrotizing enterocolitis. Is an ortholog of human PARP1 (poly(ADP-ribose) polymerase 1). WB:WBGene00004050 parp-2 Enables NAD+ ADP-ribosyltransferase activity. Predicted to be involved in double-strand break repair. Predicted to be located in nucleolus. Is an ortholog of human PARP2 (poly(ADP-ribose) polymerase 2). WB:WBGene00004051 parg-1 Enables poly(ADP-ribose) glycohydrolase activity. Involved in nucleotide-sugar metabolic process and response to gamma radiation. Located in neuron projection and nucleus. Expressed in tail neurons and ventral cord neurons. Is an ortholog of human BPHL (biphenyl hydrolase like) and PARG (poly(ADP-ribose) glycohydrolase). WB:WBGene00004052 parg-2 Enables poly(ADP-ribose) glycohydrolase activity. Involved in nucleotide-sugar metabolic process and response to gamma radiation. Located in cytoplasm. Expressed in head neurons and tail neurons. Is an ortholog of human BPHL (biphenyl hydrolase like) and PARG (poly(ADP-ribose) glycohydrolase). WB:WBGene00004053 tank-1 Predicted to enable NAD+ ADP-ribosyltransferase activity and NAD+-protein ADP-ribosyltransferase activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of programmed cell death; and response to gamma radiation. Located in nucleus. WB:WBGene00004054 AC8.1 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Alovudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00004055 pmk-1 Enables MAP kinase activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including behavioral response to nicotine; defense response to other organism; and response to inorganic substance. Located in cytosol and nucleus. Expressed in several structures, including germ line; head neurons; intestine; and vulval precursor cell. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple). Is an ortholog of human MAPK11 (mitogen-activated protein kinase 11) and MAPK14 (mitogen-activated protein kinase 14). WB:WBGene00004056 pmk-2 Enables MAP kinase activity. Involved in intracellular signal transduction and response to osmotic stress. Located in cytoplasm. Expressed in ganglia; gonad; intestine; and nerve ring. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple). Is an ortholog of human MAPK11 (mitogen-activated protein kinase 11) and MAPK14 (mitogen-activated protein kinase 14). WB:WBGene00004057 pmk-3 Enables protein kinase binding activity and protein serine/threonine kinase activity. Involved in several processes, including behavioral response to nicotine; p38MAPK cascade; and regulation of axon extension. Located in cytoplasm and nucleus. Expressed in several structures, including amphid neurons; gonad; and intestine. WB:WBGene00004058 pmp-1 Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in Zellweger syndrome and congenital bile acid synthesis defect 5. Is an ortholog of human ABCD3 (ATP binding cassette subfamily D member 3). WB:WBGene00004059 pmp-2 Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in peroxisomal membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in Zellweger syndrome and congenital bile acid synthesis defect 5. Is an ortholog of human ABCD3 (ATP binding cassette subfamily D member 3). WB:WBGene00004060 pmp-3 Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in peroxisomal membrane. Is an ortholog of human ABCD4 (ATP binding cassette subfamily D member 4). WB:WBGene00004061 pmp-4 Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in peroxisomal membrane. Used to study adrenoleukodystrophy. Human ortholog(s) of this gene implicated in adrenoleukodystrophy. Is an ortholog of human ABCD1 (ATP binding cassette subfamily D member 1) and ABCD2 (ATP binding cassette subfamily D member 2). WB:WBGene00004062 pmp-5 Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in peroxisomal membrane. Is an ortholog of human ABCD4 (ATP binding cassette subfamily D member 4). WB:WBGene00004063 pmr-1 Enables P-type calcium transporter activity and P-type manganese transporter activity. Involved in several processes, including metal ion transport; response to metal ion; and response to oxidative stress. Located in Golgi apparatus and membrane. Expressed in male gonad; seam cell; and spermatheca. Human ortholog(s) of this gene implicated in Hailey-Hailey disease. Is an ortholog of human ATP2C1 (ATPase secretory pathway Ca2+ transporting 1) and ATP2C2 (ATPase secretory pathway Ca2+ transporting 2). WB:WBGene00004064 pms-2 Predicted to enable ATP hydrolysis activity. Predicted to be involved in mismatch repair. Predicted to be part of MutLalpha complex. Human ortholog(s) of this gene implicated in several diseases, including hereditary nonpolyposis colorectal cancer type 4; mismatch repair cancer syndrome; and reproductive organ cancer (multiple). Is an ortholog of human PMS2 (PMS1 homolog 2, mismatch repair system component). WB:WBGene00004066 pna-2 No description available WB:WBGene00004068 pnk-1 Predicted to enable pantothenate kinase activity. Predicted to be involved in coenzyme A biosynthetic process. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in cataract. Is an ortholog of human PANK4 (pantothenate kinase 4 (inactive)). WB:WBGene00004070 pnm-2 No description available WB:WBGene00004071 pnm-3 No description available WB:WBGene00004072 pnm-4 No description available WB:WBGene00004073 pnm-5 No description available WB:WBGene00004074 pnm-6 No description available WB:WBGene00004075 pod-1 Enables actin filament binding activity. Located in cell cortex of cell tip and cleavage furrow. Is an ortholog of human CORO7 (coronin 7). WB:WBGene00004076 pod-2 Predicted to enable acetyl-CoA carboxylase activity. Involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; nematode larval development; and polarity specification of anterior/posterior axis. Predicted to be located in endoplasmic reticulum membrane and mitochondrion. Expressed in CANL; CANR; and excretory duct. Used to study muscular disease. Is an ortholog of human ACACA (acetyl-CoA carboxylase alpha). WB:WBGene00004077 pop-1 Enables several functions, including beta-catenin binding activity; enzyme binding activity; and transcription corepressor binding activity. Involved in several processes, including mesodermal cell fate commitment; regulation of cell division; and regulation of gene expression. Located in cytoplasm and nucleus. Expressed in several structures, including ABplpapaaa; ABprpapaaa; oocyte; somatic nervous system; and vulva. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including diabetes mellitus (multiple); endocrine gland cancer (multiple); and prostate disease (multiple). Is an ortholog of human TCF7L2 (transcription factor 7 like 2). WB:WBGene00004078 pos-1 Enables mRNA 3'-UTR binding activity; poly(U) RNA binding activity; and transcription corepressor activity. Involved in several processes, including cell fate specification; embryonic pattern specification; and negative regulation of transcription by RNA polymerase II. Located in P granule. Expressed in several structures, including Psub4; germ line; neurons; oocyte; and rectal gland cell. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein); ZFP36L1 (ZFP36 ring finger protein like 1); and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00004083 pph-1 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00004084 pph-2 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00004085 pph-4.1 Predicted to enable protein serine/threonine phosphatase activity. Involved in chiasma assembly; embryo development; and regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination. Located in centrosome and cytoplasm. Is an ortholog of human PPP4C (protein phosphatase 4 catalytic subunit). WB:WBGene00004086 pph-4.2 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in double-strand break repair via homologous recombination. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human PPP4C (protein phosphatase 4 catalytic subunit). WB:WBGene00004087 ppk-1 Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity and calmodulin binding activity. Involved in protein localization and regulation of mitotic spindle elongation. Located in plasma membrane. Expressed in egg-laying apparatus; gonad; seam cell; and ventral nerve cord. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Is an ortholog of human PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha). WB:WBGene00004088 ppk-2 Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity and 1-phosphatidylinositol-5-phosphate 4-kinase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to be located in plasma membrane. Is an ortholog of human PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha). WB:WBGene00004089 ppk-3 Predicted to enable 1-phosphatidylinositol-3-phosphate 5-kinase activity and phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Located in axon; cytoplasm; and neuronal cell body. Expressed in hypodermis; non-striated muscle; somatic nervous system; and tail neurons. Human ortholog(s) of this gene implicated in Fleck corneal dystrophy. Is an ortholog of human PIKFYVE (phosphoinositide kinase, FYVE-type zinc finger containing). WB:WBGene00004090 eif-2Bgamma Predicted to enable guanyl-nucleotide exchange factor activity and translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Located in cytoplasm. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter 3. Is an ortholog of human EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma). WB:WBGene00004091 pps-1 Predicted to enable adenylylsulfate kinase activity. Predicted to be involved in 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process and sulfate assimilation. Predicted to be located in nucleus. Expressed in epithelial cell and pharyngeal gland cell. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Pakistani type. Is an ortholog of human PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) and PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2). WB:WBGene00004092 ppt-1 Enables palmitoyl-(protein) hydrolase activity. Involved in several processes, including egg-laying behavior; mitochondrion organization; and protein catabolic process. Predicted to be located in lysosome. Used to study neuronal ceroid lipofuscinosis. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 1. Is an ortholog of human PPT1 (palmitoyl-protein thioesterase 1). WB:WBGene00004093 ppw-1 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. WB:WBGene00004094 ppw-2 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. WB:WBGene00004095 pqe-1 Predicted to enable exonuclease activity. Involved in negative regulation of gene expression. Located in nucleus. Expressed in ventral cord neurons. Is an ortholog of human REXO1 (RNA exonuclease 1 homolog). WB:WBGene00004096 pqm-1 Predicted to enable chromatin insulator sequence binding activity. Involved in several processes, including defense response to other organism; positive regulation of macromolecule metabolic process; and regulation of vitellogenesis. Located in cytoplasm and nucleus. Expressed in head muscle; head neurons; intestinal cell; neurons; and pseudocoelom. WB:WBGene00004098 pqn-2 Enriched in ALML; ALMR; BDUL; BDUR; and pharynx based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including aldicarb; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00004099 abu-15 Involved in endoplasmic reticulum unfolded protein response and pharynx development. Expressed in pharyngeal muscle cell. WB:WBGene00004100 pqn-8 Involved in pharyngeal gland morphogenesis. Expressed in g1. WB:WBGene00004101 hgrs-1 Enables ubiquitin binding activity. Involved in protein localization to non-motile cilium. Located in early endosome and endosome membrane. Part of ESCRT-0 complex. Expressed in several structures, including coelomocyte; excretory canal; hermaphrodite gonad; intestine; and vulva. Is an ortholog of human HGS (hepatocyte growth factor-regulated tyrosine kinase substrate). WB:WBGene00004102 pqn-10 Predicted to be located in membrane. WB:WBGene00004103 pqn-11 Enriched in male-specific anatomical entity based on microarray studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00004104 pqn-13 Enriched in several structures, including head mesodermal cell; neurons; pharyngeal-intestinal valve; pharynx; and posterior arcade cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-eight chemicals including 1-methylnicotinamide; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Cysteine rich repeat, tripleX and Cysteine rich repeat. WB:WBGene00004105 szy-20 Predicted to enable RNA binding activity. Involved in several processes, including negative regulation of protein localization to centrosome; positive regulation of fertilization; and regulation of cell cycle. Located in centrosome; cytoplasm; and nucleolus. WB:WBGene00004106 pqn-15 Predicted to enable ATP-dependent activity, acting on DNA and DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including Coffin-Siris syndrome 4; carcinoma (multiple); and rhabdoid cancer. Is an ortholog of human SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4). WB:WBGene00004107 pqn-16 Enriched in AMshL and AMshR based on single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and lin-35 based on microarray and RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00004108 pqn-18 Enriched in head mesodermal cell; intestine; lateral ganglion; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including stavudine; Zidovudine; and paraquat based on RNA-seq and microarray studies. WB:WBGene00004109 stam-1 Enables ubiquitin binding activity. Involved in several processes, including cellular localization; ephrin receptor signaling pathway; and response to hermaphrodite contact. Located in cilium and early endosome. Part of ESCRT-0 complex. Expressed in CEM; male gonad; neurons; and pharyngeal-intestinal valve. Used to study polycystic kidney disease. Is an ortholog of human STAM (signal transducing adaptor molecule). WB:WBGene00004110 pqn-20 Enriched in AVK; OLL; PVD; and germ line based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by eight chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00004111 pqn-21 Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including body wall musculature; intestine; spermatheca; tail; and ventral nerve cord. WB:WBGene00004112 pqn-22 Enriched in DB neuron; germ line; and muscle cell based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including methylmercuric chloride; Alovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Zasp-like motif. WB:WBGene00004113 pqn-24 Located in mitochondrion. Expressed in head muscle. WB:WBGene00004114 pqn-25 Predicted to be located in membrane. Expressed in intestine and pharyngeal gland cell. WB:WBGene00004115 pqn-26 Enriched in GABAergic neurons; arcade cell; head mesodermal cell; and pharynx based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including D-glucose; sesamin; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Thioredoxin-like superfamily. WB:WBGene00004116 pqn-27 Enriched in AFD; AVK; NSM; and germ line based on RNA-seq studies. Is affected by several genes including daf-16; age-1; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by seven chemicals including nicotine; Zidovudine; and stearic acid based on proteomic; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: Armadillo-type fold and Phosphorylation site. WB:WBGene00004117 sin-3 Contributes to histone deacetylase activity. Involved in several processes, including cell fate specification; nematode male tail mating organ morphogenesis; and vulval development. Acts upstream of or within defense response to other organism and response to endoplasmic reticulum stress. Predicted to be located in nucleus. Predicted to be part of Sin3 complex. Expressed in CEP; inner labial neurons; ray structural cell; socket cell; and ventral nerve cord. Human ortholog(s) of this gene implicated in Huntington's disease and chromosome 15q24 deletion syndrome. Is an ortholog of human SIN3A (SIN3 transcription regulator family member A) and SIN3B (SIN3 transcription regulator family member B). WB:WBGene00004118 pqn-29 Enriched in ABaraappaa; AFD; and pharynx based on microarray; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; Cadmium Chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00004119 pqn-31 Enriched in head mesodermal cell and pharynx based on RNA-seq studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-one chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00004120 pqn-32 Enriched in hypodermis; interfacial epithelial cell; intestine; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-nine chemicals including hydrogen sulfide; Nitric Oxide; and methylmercury hydroxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00004121 ptrn-1 Enables microtubule minus-end binding activity. Involved in cytoplasmic microtubule organization and nematode larval development. Located in microtubule minus-end. Expressed in hypodermis; intestine; nervous system; and pharynx. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Is an ortholog of human CAMSAP1 (calmodulin regulated spectrin associated protein 1); CAMSAP2 (calmodulin regulated spectrin associated protein family member 2); and CAMSAP3 (calmodulin regulated spectrin associated protein family member 3). WB:WBGene00004122 pqn-35 Predicted to be located in membrane. Expressed in pharyngeal muscle cell. WB:WBGene00004123 pqn-36 Enriched in ABalappaap; interfacial epithelial cell; neurons; retrovesicular ganglion; and tail hypodermis based on microarray and single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; metformin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00004124 pqn-37 Enriched in ABarpapaapp; ABplaaaaapp; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cystine-knot cytokine. WB:WBGene00004125 mdt-30 Enriched in several structures, including ABalpppapa; AVA; GLR; germ line; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; sir-2.1; and npr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00004126 pqn-39 Enriched in ABplpppppp; ABprpppppp; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00004127 abu-12 Enriched in anterior ganglion (ant); head mesodermal cell; hypodermis; interfacial epithelial cell; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00004128 pqn-41 Predicted to be located in cytoplasm. Expressed in several structures, including linker cell. WB:WBGene00004129 pqn-42 Enriched in GABAergic neurons and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00004130 ketn-1 Predicted to enable actin binding activity. Located in I band. Expressed in anal depressor muscle; body wall musculature; male gonad; and pharyngeal muscle cell. WB:WBGene00004131 tent-5 Predicted to enable poly(A) RNA polymerase activity. Predicted to be involved in mRNA stabilization. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; osteoarthritis; and osteogenesis imperfecta type 18. Is an ortholog of human TENT5A (terminal nucleotidyltransferase 5A); TENT5B (terminal nucleotidyltransferase 5B); and TENT5D (terminal nucleotidyltransferase 5D). WB:WBGene00004132 ifet-1 Predicted to enable mRNA binding activity. Involved in negative regulation of translation. Located in P granule. Part of messenger ribonucleoprotein complex. Expressed in gonad. Is an ortholog of human EIF4ENIF1 (eukaryotic translation initiation factor 4E nuclear import factor 1). WB:WBGene00004133 abu-13 Enriched in arc ant V; hypodermis; mechanosensory neurons; rectal epithelial cell; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-seven chemicals including Ethanol; Nitric Oxide; and methylmercury hydroxide based on RNA-seq and microarray studies. WB:WBGene00004134 myrf-1 Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in ecdysis, collagen and cuticulin-based cuticle and nematode larval development. Located in basal part of cell and endoplasmic reticulum. Expressed in several structures, including ciliated neurons; excretory duct; gonad; pharyngeal cell; and somatic nervous system. Human ortholog(s) of this gene implicated in cerebral infarction; congenital diaphragmatic hernia; and eye disease (multiple). Is an ortholog of human MYRFL (myelin regulatory factor like). WB:WBGene00004135 pqn-48 Predicted to enable oxidoreductase activity. Is an ortholog of human IFI30 (IFI30 lysosomal thiol reductase). WB:WBGene00004136 pqn-51 Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIA complex. Is an ortholog of human GTF2A1 (general transcription factor IIA subunit 1). WB:WBGene00004138 pqn-53 Located in nucleus. WB:WBGene00004139 pqn-54 Enriched in DA neuron; VA neuron; pharynx; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-seven chemicals including hydrogen sulfide; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00004140 ebax-1 Enables Hsp90 protein binding activity; misfolded protein binding activity; and signaling receptor binding activity. Involved in positive regulation of miRNA catabolic process; regulation of locomotion; and regulation of reproductive process. Located in axon; cytosol; and neuronal cell body. Part of Cul2-RING ubiquitin ligase complex. Expressed in excretory cell; nervous system; and vulval muscle. Is an ortholog of human ZSWIM8 (zinc finger SWIM-type containing 8). WB:WBGene00004141 pqn-57 Expressed in pharyngeal muscle cell and rectum. WB:WBGene00004143 pqn-59 Predicted to be located in cytoplasm and nucleus. Expressed widely. Is an ortholog of human UBAP2L (ubiquitin associated protein 2 like). WB:WBGene00004144 srlf-35 Enriched in ABaraapapaa; ABaraapppaa; arcade cell; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty chemicals including methylmercuric chloride; Mercuric Chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00004145 pqn-62 Enriched in Cappppv; Cpppppv; body wall muscle cell; head mesodermal cell; and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: SAP domain superfamily. WB:WBGene00004146 pqn-63 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; ASE; and cholinergic neurons based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-nine chemicals including cholesterol; lathosterol; and hydrogen sulfide based on microarray and RNA-seq studies. WB:WBGene00004147 larp-5 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in positive regulation of translation. Predicted to be located in cytoplasmic stress granule and cytosol. Expressed in PVDL; PVDR; and neurons. Is an ortholog of human LARP4 (La ribonucleoprotein 4) and LARP4B (La ribonucleoprotein 4B). WB:WBGene00004148 pqn-65 Expressed in gonad. WB:WBGene00004149 trpl-5 Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in membrane. WB:WBGene00004150 pqn-67 Expressed in tail. Is predicted to encode a protein with the following domain: Cysteine-rich repeat. WB:WBGene00004151 pqn-68 Predicted to enable D-tyrosyl-tRNA(Tyr) deacylase activity. Predicted to be involved in tRNA metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human DTD1 (D-aminoacyl-tRNA deacylase 1). WB:WBGene00004152 pqn-70 Enriched in germ line; head mesodermal cell; and neurons based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including hsf-1; gld-1; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00004153 pqn-71 Enriched in several structures, including arcade cell; mechanosensory neurons; nerve ring neurons; pharyngeal-intestinal valve cell; and pharynx based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including aldicarb; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00004154 pqn-72 Predicted to be involved in actin filament polymerization. Predicted to be located in actin filament. WB:WBGene00004155 pqn-73 Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in membrane. Predicted to be part of mediator complex. Expressed in arcade cell. WB:WBGene00004156 pqn-74 Predicted to enable chitin binding activity. Involved in endoplasmic reticulum unfolded protein response. Predicted to be located in extracellular region. WB:WBGene00004157 pqn-75 Expressed in pharyngeal gland cell and pharynx. WB:WBGene00004158 pqn-76 Is affected by several genes including daf-2; sir-2.1; and adr-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Neurotoxins; Cry5B; and silicon dioxide nanoparticle based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1096 and Protein of unknown function (DUF1096). WB:WBGene00004159 pqn-78 Is affected by several genes including daf-2; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including aldicarb; Neurotoxins; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1096 and Protein of unknown function (DUF1096). WB:WBGene00004160 pqn-79 Is affected by several genes including daf-2; pmk-1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including aldicarb; Neurotoxins; and Cry5B based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1096 and Protein of unknown function (DUF1096). WB:WBGene00004161 pqn-80 Enriched in ABalppppppa; ABpraaapppa; and body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and lin-39 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including rotenone; D-glucose; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Hpc2-related domain and HPC2 and ubinuclein domain. WB:WBGene00004163 pqn-82 Expressed in intestine. WB:WBGene00004164 pqn-83 Predicted to be located in membrane. WB:WBGene00004165 pqn-84 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00004166 scc-2 Enables cohesin loader activity. Involved in several processes, including chromosome organization; double-strand break repair involved in meiotic recombination; and regulation of cell cycle process. Located in chromosome and nucleus. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 1. Is an ortholog of human NIPBL (NIPBL cohesin loading factor). WB:WBGene00004167 pqn-87 Enriched in AVK; PDB; RIS; and germ line based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; daf-12; and let-7 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by eight chemicals including rotenone; Tunicamycin; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00004168 pqn-88 Enriched in MSaapaapa; MSpapaapa; and pharyngeal gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00004169 pqn-89 Predicted to be located in membrane. WB:WBGene00004170 pqn-90 Is affected by several genes including clk-1; aak-2; and lin-15B based on microarray; RNA-seq; and tiling array studies. Is affected by fifteen chemicals including aldicarb; sodium arsenite; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00004171 pqn-91 Is affected by several genes including sir-2.1; aak-2; and lin-15B based on microarray and RNA-seq studies. Is affected by five chemicals including Heme; sodium arsenite; and Neurotoxins based on microarray and RNA-seq studies. WB:WBGene00004172 pqn-92 Expressed in head neurons and pharynx. WB:WBGene00004173 pqn-94 Enriched in pharyngeal muscle cell and pm7 based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including rotenone; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00004174 abu-14 Involved in pharynx development. Expressed in buccal cavity; cuticle; grinder; marginal cell; and pharyngeal muscle cell. WB:WBGene00004175 pqn-96 Enriched in MSpppaaa; germ line; germline precursor cell; head mesodermal cell; and mc3 based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; sir-2.1; and clk-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00004176 srlf-36 Predicted to be located in membrane. WB:WBGene00004177 srlf-37 Predicted to be located in membrane. WB:WBGene00004178 prg-1 Enables 21U-RNA binding activity. Involved in 21U-RNA metabolic process; gamete generation; and positive regulation of mitotic nuclear division. Located in P granule. Expressed in germ line. Is an ortholog of human PIWIL1 (piwi like RNA-mediated gene silencing 1) and PIWIL3 (piwi like RNA-mediated gene silencing 3). WB:WBGene00004179 prg-2 Expressed in germ line. WB:WBGene00004180 pri-1 Predicted to enable DNA primase activity and metal ion binding activity. Predicted to be involved in DNA replication, synthesis of RNA primer. Predicted to be part of alpha DNA polymerase:primase complex. Is an ortholog of human PRIM1 (DNA primase subunit 1). WB:WBGene00004181 pri-2 Predicted to enable 4 iron, 4 sulfur cluster binding activity; DNA binding activity; and metal ion binding activity. Involved in positive regulation of nematode male tail tip morphogenesis. Predicted to be part of alpha DNA polymerase:primase complex. Is an ortholog of human PRIM2 (DNA primase subunit 2). WB:WBGene00004182 prk-1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cytoplasm. WB:WBGene00004183 prk-2 Predicted to enable protein serine/threonine kinase activity. Involved in regulation of synapse assembly. Predicted to be located in cytoplasm. Is an ortholog of human PIM1 (Pim-1 proto-oncogene, serine/threonine kinase). WB:WBGene00004184 ptp-4A2 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human PTP4A2 (protein tyrosine phosphatase 4A2). WB:WBGene00004185 pro-1 Involved in germ cell development; gonad development; and rRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of Rix1 complex and nuclear pre-replicative complex. Expressed widely. Is an ortholog of human WDR18 (WD repeat domain 18). WB:WBGene00004186 prpf-4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Is an ortholog of human PRPF4B (pre-mRNA processing factor 4B). WB:WBGene00004187 prp-8 Predicted to enable pre-mRNA intronic binding activity and snRNA binding activity. Predicted to be involved in spliceosomal tri-snRNP complex assembly. Predicted to be located in nucleus. Predicted to be part of U5 snRNP and catalytic step 2 spliceosome. Expressed in germ line. Used to study retinitis pigmentosa 13. Human ortholog(s) of this gene implicated in retinitis pigmentosa 13. Is an ortholog of human PRPF8 (pre-mRNA processing factor 8). WB:WBGene00004188 prp-21 Predicted to enable RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP; U2-type prespliceosome; and catalytic step 2 spliceosome. Is an ortholog of human SF3A1 (splicing factor 3a subunit 1). WB:WBGene00004189 pars-1 Predicted to enable proline-tRNA ligase activity. Predicted to be involved in prolyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Predicted to be part of aminoacyl-tRNA synthetase multienzyme complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 15. Is an ortholog of human EPRS1 (glutamyl-prolyl-tRNA synthetase 1). WB:WBGene00004190 pars-2 Predicted to enable proline-tRNA ligase activity. Predicted to be involved in prolyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 75. Is an ortholog of human PARS2 (prolyl-tRNA synthetase 2, mitochondrial). WB:WBGene00004191 prx-1 Predicted to enable ATP hydrolysis activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to be located in cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in Heimler syndrome 1; peroxisome biogenesis disorder 1A; and peroxisome biogenesis disorder 1B. Is an ortholog of human PEX1 (peroxisomal biogenesis factor 1). WB:WBGene00004192 prx-2 Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 5A. Is an ortholog of human PEX2 (peroxisomal biogenesis factor 2). WB:WBGene00004193 prx-3 Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in protein import into peroxisome membrane. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 10A. Is an ortholog of human PEX3 (peroxisomal biogenesis factor 3). WB:WBGene00004194 prx-5 Enables peroxisome targeting sequence binding activity. Involved in nematode larval development and protein import into peroxisome matrix. Predicted to be located in cytosol and peroxisomal membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Is an ortholog of human PEX5 (peroxisomal biogenesis factor 5). WB:WBGene00004195 prx-6 Predicted to enable ATP hydrolysis activity. Involved in nematode larval development. Predicted to be located in cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in Heimler syndrome 2 and peroxisome biogenesis disorder 4A. Is an ortholog of human PEX6 (peroxisomal biogenesis factor 6). WB:WBGene00004196 prx-11 Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in peroxisomal membrane. Is an ortholog of human PEX11G (peroxisomal biogenesis factor 11 gamma). WB:WBGene00004197 prx-12 Predicted to enable ubiquitin-protein transferase activity. Involved in nematode larval development and peroxisome organization. Predicted to be located in peroxisomal membrane. Predicted to be part of peroxisomal importomer complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 3A and peroxisome biogenesis disorder 3B. Is an ortholog of human PEX12 (peroxisomal biogenesis factor 12). WB:WBGene00004198 prx-13 Involved in nematode larval development. Predicted to be located in peroxisomal membrane. Predicted to be part of peroxisomal importomer complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 11A. Is an ortholog of human PEX13 (peroxisomal biogenesis factor 13). WB:WBGene00004199 prx-14 Predicted to enable signaling receptor binding activity. Predicted to be involved in protein import into peroxisome matrix, docking. Predicted to be located in peroxisomal membrane. Predicted to be part of peroxisomal importomer complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 13A. Is an ortholog of human PEX14 (peroxisomal biogenesis factor 14). WB:WBGene00004200 prx-16 No description available WB:WBGene00004201 prx-19 Predicted to enable peroxisome membrane targeting sequence binding activity. Involved in nematode larval development. Predicted to be located in peroxisomal membrane. Expressed in pharynx. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 12A. Is an ortholog of human PEX19 (peroxisomal biogenesis factor 19). WB:WBGene00004202 pry-1 Enables ubiquitin ligase-substrate adaptor activity. Involved in several processes, including axon guidance; negative regulation of vulval development; and proteasome-mediated ubiquitin-dependent protein catabolic process. Located in cell cortex; membrane; and nucleus. Part of beta-catenin destruction complex. Expressed in several structures, including QL.a; hypodermal cell; neurons; ventral cord blast cell; and vulval precursor cell. WB:WBGene00004203 swsn-1 Enables identical protein binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of vulval development; and positive regulation of growth rate. Predicted to be part of SWI/SNF complex. Expressed in several structures, including vulval cell. Used to study alcohol use disorder and cancer. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 8; carcinoma (multiple); and hydrocephalus. Is an ortholog of human SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1) and SMARCC2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2). WB:WBGene00004204 swsn-4 Predicted to enable ATP-dependent activity, acting on DNA and DNA binding activity. Involved in gonad development. Predicted to be located in nucleus. Expressed in several structures, including head; hyp7 syncytium; tail; ventral cord neurons; and vulval cell. Used to study alcohol use disorder and cancer. Human ortholog(s) of this gene implicated in several diseases, including Coffin-Siris syndrome 4; carcinoma (multiple); and rhabdoid cancer. Is an ortholog of human SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2) and SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4). WB:WBGene00004205 psr-1 Enables identical protein binding activity and phosphatidylserine binding activity. Involved in engulfment of apoptotic cell. Located in plasma membrane. Expressed in engulfing cell. Is an ortholog of human JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase). WB:WBGene00004206 pst-1 Enables 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity. Involved in 3'-phosphoadenosine 5'-phosphosulfate transport. Located in Golgi cisterna membrane. Expressed in AMshL; AMshR; pharyngeal gland cell; and seam cell. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 26. Is an ortholog of human SLC35B2 (solute carrier family 35 member B2). WB:WBGene00004207 ptb-1 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome and regulation of RNA splicing. Predicted to be located in nucleus. Expressed in several structures, including amphid neurons; head; muscle cell; somatic gonad; and tail. Is an ortholog of human PTBP1 (polypyrimidine tract binding protein 1); PTBP2 (polypyrimidine tract binding protein 2); and PTBP3 (polypyrimidine tract binding protein 3). WB:WBGene00004208 ptc-1 Predicted to enable hedgehog family protein binding activity; hedgehog receptor activity; and smoothened binding activity. Involved in molting cycle. Located in plasma membrane. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); colorectal adenoma; and holoprosencephaly 7. Is an ortholog of human PTCH1 (patched 1) and PTCH2 (patched 2). WB:WBGene00004209 ptc-2 Enriched in several structures, including coelomocyte; germ line; germline precursor cell; rectal epithelial cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by paraquat and Sirolimus based on microarray studies. WB:WBGene00004210 ptc-3 Predicted to enable hedgehog family protein binding activity; hedgehog receptor activity; and smoothened binding activity. Involved in molting cycle. Located in apical plasma membrane and cytoplasmic vesicle. Expressed in several structures, including CEP; cloaca; egg-laying apparatus; excretory duct; and preanal ganglion. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); colorectal adenoma; and holoprosencephaly 7. Is an ortholog of human PTCH1 (patched 1) and PTCH2 (patched 2). WB:WBGene00004211 ptd-2 Predicted to enable transmembrane transporter activity. Predicted to be involved in smoothened signaling pathway. Predicted to be located in membrane. Is an ortholog of human DISP1 (dispatched RND transporter family member 1). WB:WBGene00004212 ptl-1 Enables kinesin binding activity and microtubule binding activity. Involved in microtubule polymerization and positive regulation of nematode male tail tip morphogenesis. Located in axon. Expressed in intestinal muscle; neurons; and tail. Used to study tauopathy. Human ortholog(s) of this gene implicated in Alzheimer's disease; brain disease (multiple); and breast cancer. Is an ortholog of human MAP4 (microtubule associated protein 4). WB:WBGene00004213 ptp-1 Predicted to enable protein tyrosine phosphatase activity. Located in sarcoplasmic reticulum. Expressed in muscle cell; nerve ring; neurons; pharyngeal nervous system; and ventral nerve cord. Is an ortholog of human PTPN3 (protein tyrosine phosphatase non-receptor type 3) and PTPN4 (protein tyrosine phosphatase non-receptor type 4). WB:WBGene00004214 ptp-2 Predicted to enable non-membrane spanning protein tyrosine phosphatase activity and phosphotyrosine residue binding activity. Involved in several processes, including nematode larval development; positive regulation of signal transduction; and positive regulation of vulval development. Located in cytoplasmic vesicle. Expressed in body wall musculature; head ganglion; pharynx; spermatheca; and tail. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 1; Noonan syndrome with multiple lentigines 1; and anogenital venereal wart. Is an ortholog of human PTPN6 (protein tyrosine phosphatase non-receptor type 6). WB:WBGene00004215 ptp-3 Enables protein tyrosine phosphatase activity. Involved in several processes, including embryonic morphogenesis; nervous system development; and neuroblast migration. Located in adherens junction and synapse. Expressed in embryonic cell; hypodermis; and nervous system. Human ortholog(s) of this gene implicated in hyperinsulinism and obesity. Is an ortholog of human PTPRD (protein tyrosine phosphatase receptor type D) and PTPRF (protein tyrosine phosphatase receptor type F). WB:WBGene00004216 ptr-1 Involved in molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Is an ortholog of human PTCHD3 (patched domain containing 3 (gene/pseudogene)). WB:WBGene00004217 ptr-2 Predicted to enable transmembrane transporter activity. Involved in mitotic cytokinesis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1) and PTCHD4 (patched domain containing 4). WB:WBGene00004218 ptr-3 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. WB:WBGene00004219 ptr-4 Involved in endocytosis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Expressed in cuticular ala; epithelial cell; hyp7 syncytium; rectum; and vulva. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1) and PTCHD4 (patched domain containing 4). WB:WBGene00004220 ptr-5 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. WB:WBGene00004221 ptr-6 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Expressed in anterior hypodermis. WB:WBGene00004222 ptr-8 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Expressed in hypodermis and rectum. WB:WBGene00004223 ptr-9 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1); PTCHD3 (patched domain containing 3 (gene/pseudogene)); and PTCHD4 (patched domain containing 4). WB:WBGene00004224 ptr-10 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Expressed in accessory cell. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1) and PTCHD4 (patched domain containing 4). WB:WBGene00004225 ptr-11 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. WB:WBGene00004226 ptr-12 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. WB:WBGene00004227 ptr-13 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. WB:WBGene00004228 ptr-14 Predicted to enable transmembrane transporter activity. Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. WB:WBGene00004229 ptr-15 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Is an ortholog of human PTCHD3 (patched domain containing 3 (gene/pseudogene)). WB:WBGene00004230 ptr-16 Predicted to be involved in endocytosis and molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1); PTCHD3 (patched domain containing 3 (gene/pseudogene)); and PTCHD4 (patched domain containing 4). WB:WBGene00004231 ptr-17 Predicted to be involved in endocytosis and molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1). WB:WBGene00004232 ptr-18 Involved in endocytosis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Located in apical plasma membrane. Expressed in hypodermal cell; seam cell; and ventral cord blast cell. WB:WBGene00004233 ptr-19 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1) and PTCHD4 (patched domain containing 4). WB:WBGene00004234 ptr-20 Involved in molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1) and PTCHD4 (patched domain containing 4). WB:WBGene00004235 ptr-21 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. WB:WBGene00004236 ptr-22 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1) and PTCHD3 (patched domain containing 3 (gene/pseudogene)). WB:WBGene00004237 ptr-23 Involved in endocytosis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Expressed in hypodermis. WB:WBGene00004238 ptr-24 Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. WB:WBGene00004239 puf-3 Enables mRNA 3'-UTR binding activity. Predicted to be involved in post-transcriptional regulation of gene expression. Predicted to be located in cytoplasm and nucleus. Expressed in germ line. WB:WBGene00004240 puf-4 Is affected by several genes including rrf-3; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by Sodium Chloride and adsorbable organic bromine compound based on RNA-seq and microarray studies. WB:WBGene00004241 puf-5 Enables mRNA 3'-UTR binding activity. Involved in positive regulation of embryonic development. Located in P granule. Expressed in germ line and oocyte. WB:WBGene00004242 puf-6 Predicted to enable mRNA 3'-UTR binding activity. Involved in germ cell development and negative regulation of cell population proliferation. Predicted to be located in cytoplasm and nucleus. WB:WBGene00004243 puf-7 Predicted to enable mRNA 3'-UTR binding activity. Involved in germ cell development. Predicted to be located in cytoplasm and nucleus. WB:WBGene00004244 puf-8 Enables mRNA 3'-UTR binding activity. Involved in male meiotic nuclear division; negative regulation of MAPK cascade; and spermatogenesis. Located in P granule and nuclear periphery. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; germ line; sperm; and vulva. Used to study obesity. Human ortholog(s) of this gene implicated in cerebellar ataxia type 47. Is an ortholog of human PUM1 (pumilio RNA binding family member 1) and PUM2 (pumilio RNA binding family member 2). WB:WBGene00004245 puf-9 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in mRNA catabolic process and negative regulation of translation. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including HSN; gonad; ventral nerve cord; vulval muscle; and vulval precursor cell. Human ortholog(s) of this gene implicated in cerebellar ataxia type 47. Is an ortholog of human PUM2 (pumilio RNA binding family member 2). WB:WBGene00004246 puf-10 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Alovudine; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00004247 pun-1 No description available WB:WBGene00004248 pus-1 Predicted to enable pseudouridine synthase activity. Predicted to be involved in mRNA pseudouridine synthesis and tRNA pseudouridine synthesis. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in myopathy, lactic acidosis, and sideroblastic anemia 1. Is an ortholog of human PUS1 (pseudouridine synthase 1). WB:WBGene00004249 pvf-1 Predicted to enable growth factor receptor binding activity. Involved in negative regulation of netrin-activated signaling pathway and nematode male tail tip morphogenesis. Predicted to be located in extracellular space. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; central nervous system cancer (multiple); diabetic retinopathy (multiple); and reproductive organ cancer (multiple). Is an ortholog of human PDGFA (platelet derived growth factor subunit A) and PDGFB (platelet derived growth factor subunit B). WB:WBGene00004250 pvl-4 No description available WB:WBGene00004251 pvl-5 No description available WB:WBGene00004252 pvl-6 No description available WB:WBGene00004253 pvp-1 No description available WB:WBGene00004254 pxf-1 Enables guanyl-nucleotide exchange factor activity. Involved in collagen and cuticulin-based cuticle development; epidermis development; and molting cycle. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in several structures, including cholinergic neurons; hermaphrodite somatic gonadal cell; hyp4; nerve ring neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 7. Is an ortholog of human RAPGEF2 (Rap guanine nucleotide exchange factor 2) and RAPGEF6 (Rap guanine nucleotide exchange factor 6). WB:WBGene00004255 epac-1 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in plasma membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in autistic disorder and congestive heart failure. Is an ortholog of human RAPGEF3 (Rap guanine nucleotide exchange factor 3). WB:WBGene00004256 pxn-1 Predicted to enable peroxidase activity. Involved in muscle attachment and positive regulation of axon guidance. Located in basement membrane. Expressed in several structures, including egg-laying apparatus; excretory cell; intestine; somatic nervous system; and spermathecal-uterine valve cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; asthma (multiple); kidney failure (multiple); and lung disease (multiple). Is an ortholog of human PXDN (peroxidasin) and PXDNL (peroxidasin like). WB:WBGene00004257 pxn-2 Predicted to enable peroxidase activity. Involved in several processes, including embryonic body morphogenesis; muscle attachment; and regulation of cellular component organization. Located in basement membrane. Expressed in PVQL; PVQR; hypodermis; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; asthma (multiple); kidney failure (multiple); and lung disease (multiple). Is an ortholog of human PXDN (peroxidasin) and PXDNL (peroxidasin like). WB:WBGene00004258 pyc-1 Predicted to enable pyruvate carboxylase activity. Predicted to be involved in gluconeogenesis and pyruvate metabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in pyruvate carboxylase deficiency disease. Is an ortholog of human PC (pyruvate carboxylase). WB:WBGene00004259 pyr-1 Predicted to enable aspartate carbamoyltransferase activity and dihydroorotase activity. Predicted to contribute to carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity. Involved in several processes, including pharyngeal gland morphogenesis; pharynx development; and pyrimidine nucleobase biosynthetic process. Predicted to be located in cytosol. Expressed in intestine. Used to study carbamoyl phosphate synthetase I deficiency disease and orotic aciduria. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 50. Is an ortholog of human CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase). WB:WBGene00004261 qid-6 No description available WB:WBGene00004264 qua-1 Involved in molting cycle and nematode larval development. Acts upstream of or within nematode male tail mating organ morphogenesis. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in several structures, including P1; P12; P2; excretory system; and hypodermal cell. WB:WBGene00004265 qui-1 Involved in response to alkaloid. Located in axon; nucleus; and somatodendritic compartment. Expressed in ganglia; head neurons; and nerve ring. WB:WBGene00004266 rab-1 Predicted to enable GTPase activity. Predicted to be involved in autophagosome assembly and intracellular protein transport. Predicted to be located in endomembrane system. Expressed in tail. Is an ortholog of human RAB1A (RAB1A, member RAS oncogene family); RAB1B (RAB1B, member RAS oncogene family); and RAB1C (RAB1C, member RAS oncogene family (pseudogene)). WB:WBGene00004267 rab-3 Predicted to enable GTPase activity and myosin V binding activity. Involved in several processes, including positive regulation of anterior/posterior axon guidance; regulation of GABAergic synaptic transmission; and ventral cord development. Located in neuron projection and synaptic vesicle. Expressed in nervous system; neurons; and uv1. Used to study alcohol use disorder and epilepsy. Is an ortholog of human RAB3A (RAB3A, member RAS oncogene family). WB:WBGene00004268 rab-5 Enables GTPase activating protein binding activity and GTPase activity. Involved in embryo development; protein localization; and vesicle-mediated transport. Located in several cellular components, including cholinergic synapse; cytoplasmic vesicle; and periciliary membrane compartment. Expressed in several structures, including ventral cord neurons. Is an ortholog of human RAB5B (RAB5B, member RAS oncogene family) and RAB5C (RAB5C, member RAS oncogene family). WB:WBGene00004269 rab-6.1 Predicted to enable GTPase activity. Involved in cortical granule exocytosis and cuticle development. Located in Golgi cisterna and cortical granule. Expressed in several structures, including RIG; command interneuron; gonad; intestine; and vulva. Is an ortholog of human RAB6A (RAB6A, member RAS oncogene family). WB:WBGene00004270 rab-6.2 Enables GTP binding activity. Involved in several processes, including early endosome to Golgi transport; positive regulation of feeding behavior; and protein stabilization. Located in Golgi trans cisterna. Expressed in several structures, including coelomocyte; command interneuron; gonad; pharynx; and vulva. Is an ortholog of human RAB6A (RAB6A, member RAS oncogene family) and RAB6B (RAB6B, member RAS oncogene family). WB:WBGene00004271 rab-7 Enables GTPase activity. Involved in several processes, including oocyte growth; positive regulation of early endosome to late endosome transport; and vesicle-mediated transport. Located in late endosome membrane; lysosome; and phagocytic vesicle membrane. Expressed in several structures, including oocyte. Used to study obesity. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B. Is an ortholog of human RAB7A (RAB7A, member RAS oncogene family). WB:WBGene00004272 rab-8 Enables GTPase activating protein binding activity and ankyrin repeat binding activity. Involved in several processes, including embryonic genitalia morphogenesis; negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; and protein secretion. Located in apical part of cell and cytoplasmic vesicle. Expressed in body wall musculature. Is an ortholog of human RAB8B (RAB8B, member RAS oncogene family). WB:WBGene00004273 rab-10 Enables GTPase activating protein binding activity and ankyrin repeat binding activity. Involved in several processes, including negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; receptor recycling; and vesicle-mediated transport. Located in several cellular components, including Golgi medial cisterna; cholinergic synapse; and cytoplasmic vesicle. Expressed in several structures, including PVD; coelomocyte; hermaphrodite gonad; hypodermis; and somatic nervous system. Is an ortholog of human RAB10 (RAB10, member RAS oncogene family). WB:WBGene00004274 rab-11.1 Predicted to enable GTP binding activity and GTPase activity. Involved in several processes, including eggshell formation; membrane addition at site of mitotic cytokinesis; and vesicle-mediated transport. Located in Golgi trans cisterna membrane; cortical granule; and recycling endosome. Expressed in gonad. Is an ortholog of human RAB11A (RAB11A, member RAS oncogene family). WB:WBGene00004275 rab-11.2 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in exocytosis. Predicted to be located in Golgi apparatus and recycling endosome. Is an ortholog of human RAB11A (RAB11A, member RAS oncogene family). WB:WBGene00004276 rab-14 Predicted to enable GTPase activity. Involved in phagolysosome assembly involved in apoptotic cell clearance and phagosome acidification involved in apoptotic cell clearance. Located in early endosome; phagocytic vesicle; and trans-Golgi network. Expressed in gonadal sheath cell; hypodermis; intestine; and pharyngeal muscle cell. Is an ortholog of human RAB14 (RAB14, member RAS oncogene family). WB:WBGene00004277 rab-18 Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport and lipid droplet organization. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in Warburg micro syndrome 3. Is an ortholog of human RAB18 (RAB18, member RAS oncogene family). WB:WBGene00004278 rab-19 Predicted to enable GTPase activity. Predicted to be involved in autophagosome assembly and intracellular protein transport. Predicted to be located in endomembrane system. Expressed in anal depressor muscle and excretory cell. Is an ortholog of human RAB43 (RAB43, member RAS oncogene family). WB:WBGene00004279 rab-21 Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to be located in early endosome. Is an ortholog of human RAB21 (RAB21, member RAS oncogene family). WB:WBGene00004281 rab-28 Predicted to enable GTPase activity. Involved in several processes, including axoneme assembly; locomotory exploration behavior; and regulation of cilium assembly. Located in cilium; neuronal cell body; and periciliary membrane compartment. Expressed in ciliated neurons and in male. Used to study ciliopathy. Human ortholog(s) of this gene implicated in cone-rod dystrophy 18. Is an ortholog of human RAB28 (RAB28, member RAS oncogene family). WB:WBGene00004282 rab-30 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in Golgi cisterna and trans-Golgi network. Is an ortholog of human RAB30 (RAB30, member RAS oncogene family). WB:WBGene00004283 rab-33 Predicted to enable GTP binding activity and GTPase activity. Predicted to be located in Golgi apparatus and endosome. Human ortholog(s) of this gene implicated in Smith-McCort dysplasia 2. Is an ortholog of human RAB33B (RAB33B, member RAS oncogene family). WB:WBGene00004284 rab-35 Enables GTPase activating protein binding activity and ankyrin repeat binding activity. Involved in endocytic recycling. Located in early endosome; plasma membrane; and recycling endosome membrane. Expressed in several structures, including oocyte. Is an ortholog of human RAB35 (RAB35, member RAS oncogene family). WB:WBGene00004285 rab-37 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in regulation of exocytosis. Predicted to be located in Golgi apparatus and endosome. Expressed in head neurons and tail neurons. Is an ortholog of human RAB26 (RAB26, member RAS oncogene family) and RAB37 (RAB37, member RAS oncogene family). WB:WBGene00004286 rab-39 Enables GTP binding activity. Involved in positive regulation of response to oxidative stress. Predicted to be located in Golgi apparatus; cytoplasmic vesicle membrane; and plasma membrane. Expressed in head mesodermal cell; head neurons; hypodermis; rectal gland cell; and tail neurons. Human ortholog(s) of this gene implicated in Waisman syndrome and non-syndromic X-linked intellectual disability 72. Is an ortholog of human RAB39A (RAB39A, member RAS oncogene family) and RAB39B (RAB39B, member RAS oncogene family). WB:WBGene00004287 rac-2 Enables GTP binding activity and GTPase activity. Involved in actin filament organization; axon guidance; and neuron migration. Located in axon and plasma membrane. Expressed in nerve ring and neurons. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant intellectual developmental disorder 48; colon adenoma; and gastrointestinal system cancer (multiple). Is an ortholog of human RAC1 (Rac family small GTPase 1). WB:WBGene00004291 rad-4 Acts upstream of or within several processes, including DNA damage response; meiotic chromosome segregation; and response to UV. WB:WBGene00004293 rad-7 Acts upstream of or within reproduction and response to UV. WB:WBGene00004295 rad-9 Acts upstream of or within embryo development; reproduction; and response to UV. WB:WBGene00004296 rad-50 Predicted to enable G-quadruplex DNA binding activity; double-stranded telomeric DNA binding activity; and single-stranded telomeric DNA binding activity. Predicted to be involved in chromosome organization and nucleic acid metabolic process. Predicted to be located in condensed nuclear chromosome. Predicted to be part of Mre11 complex. Human ortholog(s) of this gene implicated in invasive ductal carcinoma and transitional cell carcinoma. Is an ortholog of human RAD50 (RAD50 double strand break repair protein). WB:WBGene00004297 rad-51 Enables several functions, including ATP hydrolysis activity; DEAD/H-box RNA helicase binding activity; and catalytic activity, acting on DNA. Involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; meiotic chromosome condensation; and negative regulation of apoptotic process. Located in condensed nuclear chromosome; germ cell nucleus; and site of double-strand break. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia complementation group R; congenital mirror movement disorder; and ovary epithelial cancer. Is an ortholog of human RAD51 (RAD51 recombinase). WB:WBGene00004298 rad-54.L Enables ATP-dependent activity, acting on DNA. Predicted to be involved in double-strand break repair via synthesis-dependent strand annealing and reciprocal meiotic recombination. Located in nucleus. Human ortholog(s) of this gene implicated in breast cancer; non-Hodgkin lymphoma; and pancreatic cancer. Is an ortholog of human RAD54L (RAD54 like). WB:WBGene00004299 ram-1 No description available WB:WBGene00004300 ram-2 Predicted to be a structural constituent of cuticle. Involved in nematode male tail tip morphogenesis and sensory organ development. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00004301 ram-5 Involved in nematode male tail tip morphogenesis. Located in plasma membrane. Expressed in ray structural cell. WB:WBGene00004302 ran-1 Predicted to enable GTPase activity. Involved in embryo development and oogenesis. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Is an ortholog of human RAN (RAN, member RAS oncogene family). WB:WBGene00004303 ran-2 Predicted to enable GTPase activator activity and small GTPase binding activity. Involved in embryo development. Predicted to be located in cytosol; nucleus; and perinuclear region of cytoplasm. Expressed in intestinal cell. Is an ortholog of human RANGAP1 (Ran GTPase activating protein 1). WB:WBGene00004304 ran-3 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in embryo development and positive regulation of nematode male tail tip morphogenesis. Predicted to be located in cytoplasm. Is an ortholog of human RCC1 (regulator of chromosome condensation 1). WB:WBGene00004305 ran-4 Predicted to enable nuclear import signal receptor activity. Predicted to be involved in protein import into nucleus. Predicted to be located in cytoplasm. Predicted to be part of nuclear pore central transport channel. Human ortholog(s) of this gene implicated in diabetic retinopathy. Is an ortholog of human NUTF2 (nuclear transport factor 2). WB:WBGene00004306 ran-5 Predicted to contribute to GTPase activator activity. Predicted to be involved in intracellular transport. Predicted to be located in cytoplasm. Predicted to be part of nuclear pore. Is an ortholog of human RANBP3 (RAN binding protein 3). WB:WBGene00004307 rap-1 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in collagen and cuticulin-based cuticle development and epidermis development. Predicted to be located in plasma membrane. Expressed in several structures, including germ line; gonad; and neurons. Is an ortholog of human RAP1A (RAP1A, member of RAS oncogene family) and RAP1B (RAP1B, member of RAS oncogene family). WB:WBGene00004308 rap-2 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in collagen and cuticulin-based cuticle development and epidermis development. Predicted to be located in plasma membrane. Expressed in DA8; DA9; and motor neurons. Is an ortholog of human RAP2A (RAP2A, member of RAS oncogene family). WB:WBGene00004309 rap-3 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Rap protein signal transduction and negative regulation of cell migration. Predicted to be located in plasma membrane. Expressed in pharynx. WB:WBGene00004310 ras-1 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in parturition and vulval development. Predicted to be located in plasma membrane. Used to study RASopathy. Human ortholog(s) of this gene implicated in Noonan syndrome 12. Is an ortholog of human RRAS (RAS related) and RRAS2 (RAS related 2). WB:WBGene00004311 ras-2 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in signal transduction. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 11. Is an ortholog of human MRAS (muscle RAS oncogene homolog). WB:WBGene00004312 rba-1 Predicted to enable histone binding activity. Involved in cell fate specification; nematode male tail tip morphogenesis; and regulation of neurogenesis. Predicted to be located in nucleus. Predicted to be part of ESC/E(Z) complex and NuRD complex. Is an ortholog of human RBBP7 (RB binding protein 7, chromatin remodeling factor). WB:WBGene00004313 rbc-1 Predicted to be involved in vacuolar acidification. Predicted to be part of RAVE complex. Expressed in several structures, including cuticle; neurons; ventral nerve cord; vm1; and vulva. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 71 and developmental and epileptic encephalopathy 81. Is an ortholog of human DMXL1 (Dmx like 1) and DMXL2 (Dmx like 2). WB:WBGene00004314 rbc-2 Predicted to be located in cytoplasm. Is an ortholog of human WDR7 (WD repeat domain 7). WB:WBGene00004315 rbd-1 Predicted to enable RNA binding activity. Involved in several processes, including collagen and cuticulin-based cuticle development; positive regulation of growth rate; and vulval development. Located in nucleolus. Is an ortholog of human RBM19 (RNA binding motif protein 19). WB:WBGene00004316 rbf-1 Predicted to enable metal ion binding activity. Involved in dense core granule exocytosis and positive regulation of locomotion. Located in synaptic vesicle. Expressed in dorsal nerve cord; nerve ring; neurons; and ventral nerve cord. Is an ortholog of human RPH3A (rabphilin 3A). WB:WBGene00004317 rbg-1 Predicted to enable GTPase activator activity and small GTPase binding activity. Involved in amyloid fibril formation; autophagy; and positive regulation of autophagosome assembly. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Warburg micro syndrome 1. Is an ortholog of human RAB3GAP1 (RAB3 GTPase activating protein catalytic subunit 1). WB:WBGene00004318 rbg-2 Predicted to enable enzyme regulator activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Martsolf syndrome and Warburg micro syndrome 2. Is an ortholog of human RAB3GAP2 (RAB3 GTPase activating non-catalytic protein subunit 2). WB:WBGene00004319 rbr-2 Enables histone H3K4me/H3K4me2/H3K4me3 demethylase activity. Involved in determination of adult lifespan and regulation of vulval development. Located in nucleus. Expressed in several structures, including anchor cell and vulval precursor cell. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of musculoskeletal system (multiple); gastrointestinal system cancer (multiple); and intellectual disability (multiple). Is an ortholog of several human genes including KDM5A (lysine demethylase 5A); KDM5C (lysine demethylase 5C); and KDM5D (lysine demethylase 5D). WB:WBGene00004320 rbx-1 Predicted to enable cullin family protein binding activity and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of intracellular signal transduction; positive regulation of metaphase/anaphase transition of meiotic cell cycle; and sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation. Part of Cul2-RING ubiquitin ligase complex. Expressed in germ line; gonad; linker cell; and oocyte. Is an ortholog of human RBX1 (ring-box 1). WB:WBGene00004321 rcan-1 Enables protein phosphatase 2B binding activity and protein serine/threonine phosphatase inhibitor activity. Involved in several processes, including male mating behavior; positive regulation of nematode male tail tip morphogenesis; and thermosensory behavior. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including non-striated muscle; pharyngeal cell; somatic nervous system; tail; and vulva. Used to study Down syndrome. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human RCAN1 (regulator of calcineurin 1); RCAN2 (regulator of calcineurin 2); and RCAN3 (RCAN family member 3). WB:WBGene00004322 rcq-5 Predicted to enable 3'-5' DNA helicase activity and four-way junction helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication and double-strand break repair via homologous recombination. Located in nucleus. Expressed in several structures, including germ line; intestinal cell; and oocyte. Is an ortholog of human RECQL5 (RecQ like helicase 5). WB:WBGene00004323 rde-1 Enables DEAD/H-box RNA helicase binding activity; RNA endonuclease activity, producing 5'-phosphomonoesters; and siRNA binding activity. Involved in obsolete conversion of ds siRNA to ss siRNA involved in RNA interference; regulatory ncRNA-mediated heterochromatin formation; and regulatory ncRNA-mediated post-transcriptional gene silencing. Part of RISC complex. WB:WBGene00004324 rde-2 Involved in several processes, including meiotic chromosome segregation and regulatory ncRNA-mediated gene silencing. Located in cytosol and mutator focus. Expressed in germ line. WB:WBGene00004326 rde-4 Enables double-stranded RNA binding activity; protein homodimerization activity; and single-stranded RNA binding activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing and siRNA processing. Part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in dystonia 16. Is an ortholog of human PRKRA (protein activator of interferon induced protein kinase EIF2AK2) and TARBP2 (TARBP2 subunit of RISC loading complex). WB:WBGene00004328 rdy-2 Predicted to be located in membrane. Expressed in excretory canal; hyp7 syncytium; and neuronal sheath cell. WB:WBGene00004330 rdy-4 No description available WB:WBGene00004331 rdy-5 No description available WB:WBGene00004332 rec-1 Involved in meiotic DNA double-strand break formation involved in reciprocal meiotic recombination. WB:WBGene00004333 rec-8 Predicted to enable chromatin binding activity and damaged DNA binding activity. Involved in double-strand break repair and organelle organization. Located in nuclear lumen and spindle. Part of chromatin. Expressed in Z2; Z3; embryonic cell; and gonad. WB:WBGene00004334 ref-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including epidermal cell fate specification; negative regulation of transcription by RNA polymerase II; and nematode male tail tip morphogenesis. Located in nucleus. Expressed in several structures, including E lineage cell; embryonic cell; intestine; mc3V; and pharyngeal cell. Is an ortholog of human HES5 (hes family bHLH transcription factor 5). WB:WBGene00004335 ref-2 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including neuron fate specification; positive regulation of transcription by RNA polymerase II; and regulation of cell division. Acts upstream of or within with a positive effect on nematode larval development. Located in nucleus. Expressed in several structures, including IL1 neuron; P3.p male; neuroblasts; rectal epithelial cell; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including Dandy-Walker syndrome; X-linked VACTERL association; and holoprosencephaly 5. Is an ortholog of several human genes including ZIC1 (Zic family member 1); ZIC2 (Zic family member 2); and ZIC3 (Zic family member 3). WB:WBGene00004336 ret-1 Located in endomembrane system. Expressed in several structures, including gonad and nervous system. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 12. Is an ortholog of human RTN3 (reticulon 3). WB:WBGene00004337 rfc-1 Predicted to enable DNA binding activity. Predicted to be involved in DNA repair and DNA replication. Predicted to be located in nucleus. Predicted to be part of DNA replication factor C complex. Human ortholog(s) of this gene implicated in West Nile fever. Is an ortholog of human RFC1 (replication factor C subunit 1). WB:WBGene00004338 rfc-2 Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA binding activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in DNA repair and DNA-templated DNA replication. Predicted to be located in nucleus. Predicted to be part of DNA replication factor C complex. Is an ortholog of human RFC2 (replication factor C subunit 2). WB:WBGene00004339 rfc-3 Predicted to enable DNA binding activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in DNA repair and DNA-templated DNA replication. Predicted to be located in nucleus. Predicted to be part of DNA replication factor C complex. Is an ortholog of human RFC3 (replication factor C subunit 3). WB:WBGene00004340 rfc-4 Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to contribute to DNA clamp loader activity. Involved in DNA replication. Predicted to be located in nucleus. Predicted to be part of DNA replication factor C complex. Is an ortholog of human RFC4 (replication factor C subunit 4). WB:WBGene00004341 rfl-1 Predicted to enable NEDD8 activating enzyme activity. Involved in negative regulation of DNA damage response, signal transduction by p53 class mediator and protein neddylation. Located in cytoplasm and nucleus. Expressed in head; tail; and vulval cell. Is an ortholog of human UBA3 (ubiquitin like modifier activating enzyme 3). WB:WBGene00004342 rfs-1 Enables ATPase binding activity. Involved in DNA recombinase assembly and resolution of meiotic recombination intermediates. Part of DNA recombinase mediator complex. Human ortholog(s) of this gene implicated in hereditary breast ovarian cancer syndrome. Is an ortholog of human RAD51D (RAD51 paralog D). WB:WBGene00004343 rgr-1 Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Expressed in germ line. Is an ortholog of human MED14 (mediator complex subunit 14). WB:WBGene00004344 rgs-1 Enables GTPase activator activity. Involved in chemosensory behavior and sensory perception of bitter taste. Expressed in head; neurons; and tail. Is an ortholog of human RGS19 (regulator of G protein signaling 19). WB:WBGene00004345 rgs-2 Enables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Expressed in head neurons; pharyngeal muscle cell; tail neurons; uterine muscle; and ventral cord neurons. Is an ortholog of human RGS19 (regulator of G protein signaling 19). WB:WBGene00004346 rgs-3 Involved in chemosensory behavior and sensory perception of bitter taste. Expressed in amphid neurons and phasmid neurons. WB:WBGene00004347 rgs-4 Enriched in head mesodermal cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; glp-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: RGS, subdomain 2; RGS domain; RGS domain superfamily; and Regulator of G protein signaling domain. WB:WBGene00004348 rgs-5 Predicted to be involved in protein localization. Predicted to be located in mitochondrion and plasma membrane. Is an ortholog of human AKAP10 (A-kinase anchoring protein 10). WB:WBGene00004349 rgs-6 Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Human ortholog(s) of this gene implicated in nephrolithiasis. Is an ortholog of human RGS14 (regulator of G protein signaling 14). WB:WBGene00004350 rgs-7 Enables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Located in cell cortex. Is an ortholog of several human genes including RGS1 (regulator of G protein signaling 1); RGS13 (regulator of G protein signaling 13); and RGS4 (regulator of G protein signaling 4). WB:WBGene00004351 rgs-8.1 Expressed in PVT and intestine. Human RGS1 enables G-protein alpha-subunit binding activity and GTPase activator activity. Is predicted to encode a protein with the following domains: RGS, subdomain 1/3; RGS, subdomain 2; RGS domain superfamily; Regulator of G protein signaling domain; and RGS domain. Is an ortholog of human RGS1 (regulator of G protein signaling 1). WB:WBGene00004352 rgs-9 Predicted to be involved in negative regulation of signal transduction. WB:WBGene00004353 rgs-10 Involved in embryo development and reproduction. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma and essential hypertension. Is an ortholog of several human genes including RGS1 (regulator of G protein signaling 1); RGS2 (regulator of G protein signaling 2); and RGS4 (regulator of G protein signaling 4). WB:WBGene00004354 rgs-11 Predicted to be involved in negative regulation of signal transduction. Is an ortholog of human RGS3 (regulator of G protein signaling 3). WB:WBGene00004355 rha-1 Predicted to enable ATP hydrolysis activity; helicase activity; and nucleic acid binding activity. Involved in germ cell development and negative regulation of gene expression, epigenetic. Predicted to be located in nucleolus. Predicted to be part of ribonucleoprotein complex. Expressed in germ line and oocyte. Is an ortholog of human DHX9 (DExH-box helicase 9). WB:WBGene00004356 rhi-1 Predicted to enable Rho GDP-dissociation inhibitor activity. Predicted to be involved in Rho protein signal transduction. Located in cytosol and membrane. Human ortholog(s) of this gene implicated in nephrotic syndrome type 8. Is an ortholog of human ARHGDIA (Rho GDP dissociation inhibitor alpha); ARHGDIB (Rho GDP dissociation inhibitor beta); and ARHGDIG (Rho GDP dissociation inhibitor gamma). WB:WBGene00004357 rho-1 Enables several functions, including GTP binding activity; GTPase activating protein binding activity; and GTPase activity. Involved in several processes, including actomyosin structure organization; positive regulation of acetylcholine secretion, neurotransmission; and positive regulation of locomotion. Located in cell cortex and cleavage furrow. Expressed widely. Human ortholog(s) of this gene implicated in several diseases, including colorectal cancer; multiple sclerosis; and ovarian carcinoma. Is an ortholog of human RHOA (ras homolog family member A). WB:WBGene00004358 rhr-1 Enables ammonium transmembrane transporter activity. Involved in ammonium transmembrane transport. Predicted to be located in plasma membrane. Expressed in head. Human ortholog(s) of this gene implicated in Rh deficiency syndrome; Rh isoimmunization; and overhydrated hereditary stomatocytosis. Is an ortholog of human RHAG (Rh associated glycoprotein); RHBG (Rh family B glycoprotein); and RHCG (Rh family C glycoprotein). WB:WBGene00004359 rhr-2 Predicted to enable ammonium transmembrane transporter activity. Predicted to be involved in ammonium homeostasis and ammonium transmembrane transport. Located in apical plasma membrane. Expressed in several structures, including body wall musculature; head neurons; spermatheca; ventral nerve cord; and vulva. Human ortholog(s) of this gene implicated in Rh deficiency syndrome and overhydrated hereditary stomatocytosis. Is an ortholog of human RHAG (Rh associated glycoprotein); RHBG (Rh family B glycoprotein); and RHCG (Rh family C glycoprotein). WB:WBGene00004360 rib-1 Enables enzyme binding activity. Contributes to acetylglucosaminyltransferase activity and glucuronosyltransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process and pharynx development. Located in protein-containing complex. Expressed in several structures, including alimentary muscle; hypodermal cell; nervous system; pharynx; and reproductive system. Used to study hereditary multiple exostoses. Human ortholog(s) of this gene implicated in chondrosarcoma and hereditary multiple exostoses. Is an ortholog of human EXTL1 (exostosin like glycosyltransferase 1). WB:WBGene00004361 rib-2 Enables enzyme binding activity and heparan sulfate N-acetylglucosaminyltransferase activity. Contributes to glucuronosyltransferase activity. Involved in embryonic morphogenesis; heparan sulfate proteoglycan biosynthetic process; and pharynx development. Located in protein-containing complex. Used to study hereditary multiple exostoses. Is an ortholog of human EXTL3 (exostosin like glycosyltransferase 3). WB:WBGene00004362 ric-1 Acts upstream of or within cholinergic synaptic transmission. WB:WBGene00004363 ric-3 Enables protein folding chaperone. Involved in several processes, including cholinergic synaptic transmission; positive regulation of cholinergic synaptic transmission; and protein localization to cell surface. Located in intracellular membrane-bounded organelle; neuron projection; and neuronal cell body. Expressed in body wall musculature; neurons; and pharyngeal muscle cell. Is an ortholog of human RIC3 (RIC3 acetylcholine receptor chaperone). WB:WBGene00004364 ric-4 Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in cholinergic synaptic transmission. Located in plasma membrane and synapse. Expressed in several structures, including CAN; excretory gland cell; mechanosensory neurons; rectal gland cell; and somatic nervous system. Human ortholog(s) of this gene implicated in Down syndrome and congenital myasthenic syndrome 18. Is an ortholog of human SNAP25 (synaptosome associated protein 25). WB:WBGene00004365 ric-6 No description available WB:WBGene00004367 ric-8 Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including negative regulation of protein kinase C signaling; protein localization to cell cortex; and regulation of feeding behavior. Located in aster; cell cortex; and kinetochore microtubule. Expressed in germ line and neurons. Is an ortholog of human RIC8A (RIC8 guanine nucleotide exchange factor A). WB:WBGene00004368 ric-19 Enables small GTPase binding activity. Involved in dense core granule maturation; regulation of locomotion involved in locomotory behavior; and regulation of neurotransmitter secretion. Located in Golgi apparatus. Expressed in several structures, including excretory system; head; intestine; muscle cell; and nervous system. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Is an ortholog of human ICA1L (islet cell autoantigen 1 like). WB:WBGene00004369 rig-1 Predicted to be located in membrane. Expressed in PVC; head ganglion; hypodermis; and pharyngeal cell. WB:WBGene00004370 rig-3 Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Located in axon and synapse. Expressed in several structures, including AVA; amphid sheath cell; coelomocyte; pharyngeal neurons; and somatic nervous system. WB:WBGene00004371 rig-4 Predicted to be involved in cell adhesion. Predicted to be located in membrane. Expressed in several structures, including DA neuron; excretory cell; somatic neurons; spermathecal-uterine junction; and vulva. Is an ortholog of human SDK1 (sidekick cell adhesion molecule 1) and SDK2 (sidekick cell adhesion molecule 2). WB:WBGene00004372 rig-5 Predicted to be located in neuron projection. Expressed in head ganglion; intestine; and pharyngeal cell. Human ortholog(s) of this gene implicated in ovarian cancer. Is an ortholog of several human genes including LSAMP (limbic system associated membrane protein); NTM (neurotrimin); and OPCML (opioid binding protein/cell adhesion molecule like). WB:WBGene00004373 rme-1 Enables ATP hydrolysis activity and protein domain specific binding activity. Involved in several processes, including endocytic recycling; lipid tube assembly involved in organelle fission; and necroptotic process. Located in recycling endosome membrane. Expressed in coelomocyte; germ line; gonad; intestine; and pharynx. Is an ortholog of human EHD1 (EH domain containing 1). WB:WBGene00004374 rme-2 Enables low-density lipoprotein particle receptor activity. Involved in embryo development; oocyte development; and ovulation. Located in endosome membrane and plasma membrane. Expressed in germ cell; germ line; and gonad. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; female reproductive organ cancer (multiple); hepatobiliary system cancer (multiple); and high grade glioma (multiple). Is an ortholog of human EGF (epidermal growth factor). WB:WBGene00004375 rme-4 Predicted to enable phosphatidylinositol phosphate binding activity. Involved in endocytic recycling. Located in clathrin-coated pit. Expressed in several structures, including engulfing cell and linker cell. Is an ortholog of human DENND1A (DENN domain containing 1A); DENND1B (DENN domain containing 1B); and DENND1C (DENN domain containing 1C). WB:WBGene00004377 rme-6 Enables small GTPase binding activity. Involved in endocytosis; molting cycle; and regulation of clathrin-dependent endocytosis. Located in clathrin-coated endocytic vesicle; early endosome; and plasma membrane. Expressed in several structures, including anterior gonad arm; coelomocyte; intestine; oocyte; and pharynx. Is an ortholog of human GAPVD1 (GTPase activating protein and VPS9 domains 1). WB:WBGene00004378 rme-8 Enables identical protein binding activity. Involved in several processes, including mechanosensory behavior; positive regulation of nematode male tail tip morphogenesis; and vesicle-mediated transport. Located in endosome. Expressed in coelomocyte; hypodermal cell; muscle cell; oocyte; and uterus. Human ortholog(s) of this gene implicated in Parkinson's disease. Is an ortholog of human DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13). WB:WBGene00004380 rnf-1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Is an ortholog of human RNF183 (ring finger protein 183). WB:WBGene00004381 rnf-5 Enables ubiquitin protein ligase activity. Involved in several processes, including inductive cell migration; striated muscle cell development; and ubiquitin-dependent protein catabolic process. Located in cell junction; nucleus; and striated muscle dense body. Expressed in head neurons; hypodermis; and tail neurons. Is an ortholog of human RNF185 (ring finger protein 185) and RNF5 (ring finger protein 5). WB:WBGene00004382 rnh-1.0 Enables RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 2. Is an ortholog of human RNASEH1 (ribonuclease H1). WB:WBGene00004383 rnh-2 Predicted to enable RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer and mismatch repair. Predicted to be part of ribonuclease H2 complex. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Is an ortholog of human RNASEH2A (ribonuclease H2 subunit A). WB:WBGene00004384 rnp-1 Predicted to enable RNA binding activity. Involved in oocyte fate commitment; positive regulation of oocyte development; and spermatogenesis. Predicted to be located in nuclear speck. Is an ortholog of human RBM4 (RNA binding motif protein 4) and RBM4B (RNA binding motif protein 4B). WB:WBGene00004385 rnp-2 Predicted to enable U1 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U1 snRNP. Human ortholog(s) of this gene implicated in Alzheimer's disease; connective tissue disease; and disease of cellular proliferation. Is an ortholog of human SNRPA (small nuclear ribonucleoprotein polypeptide A) and SNRPB2 (small nuclear ribonucleoprotein polypeptide B2). WB:WBGene00004386 rnp-3 Predicted to enable U1 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U1 snRNP. Human ortholog(s) of this gene implicated in Alzheimer's disease; connective tissue disease; and disease of cellular proliferation. Is an ortholog of human SNRPA (small nuclear ribonucleoprotein polypeptide A) and SNRPB2 (small nuclear ribonucleoprotein polypeptide B2). WB:WBGene00004387 rnp-4 Enables U2 snRNA binding activity; mRNA binding activity; and pre-mRNA binding activity. Involved in several processes, including feminization of hermaphroditic germ-line; nuclear mRNA surveillance; and positive regulation of oogenesis. Located in cytoplasm and nucleus. Expressed in several structures, including germ line. Human ortholog(s) of this gene implicated in thrombocytopenia-absent radius syndrome. Is an ortholog of human RBM8A (RNA binding motif protein 8A). WB:WBGene00004388 rnp-5 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of ASAP complex. Is an ortholog of human RNPS1 (RNA binding protein with serine rich domain 1). WB:WBGene00004389 rnp-6 Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome; mRNA splice site recognition; and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human PUF60 (poly(U) binding splicing factor 60). WB:WBGene00004390 rnp-7 Predicted to enable U1 snRNA binding activity and mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U1 snRNP and U2-type prespliceosome. Human ortholog(s) of this gene implicated in Alzheimer's disease; disease of mental health; and systemic lupus erythematosus. Is an ortholog of human SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70). WB:WBGene00004391 rnr-1 Predicted to enable ATP binding activity and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to be part of ribonucleoside-diphosphate reductase complex. Expressed in head; somatic gonad precursor; and tail. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human RRM1 (ribonucleotide reductase catalytic subunit M1). WB:WBGene00004392 rnr-2 Predicted to enable ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Involved in embryo development. Predicted to be located in cytosol. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 5; lung non-small cell carcinoma; and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human RRM2 (ribonucleotide reductase regulatory subunit M2). WB:WBGene00004393 rnt-1 Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Involved in several processes, including nematode male tail tip morphogenesis; positive regulation of locomotion involved in locomotory behavior; and regulation of gene expression. Acts upstream of or within dopamine metabolic process. Located in nucleus. Part of core-binding activity factor complex. Expressed in body wall musculature; intestine; neurons; ray precursor cell; and seam cell. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); invasive ductal carcinoma; and osteochondrodysplasia (multiple). Is an ortholog of human RUNX2 (RUNX family transcription factor 2) and RUNX3 (RUNX family transcription factor 3). WB:WBGene00004394 rol-1 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00004395 rol-3 Predicted to enable ATP binding activity and protein kinase activity. Involved in embryo development and locomotion. Located in cell leading edge and cell periphery. Expressed in head; seam cell; and vulval precursor cell. Is an ortholog of human ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase). WB:WBGene00004397 rol-6 A structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in hypodermis. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 5. Is an ortholog of human COLQ (collagen like tail subunit of asymmetric acetylcholinesterase). WB:WBGene00004398 rol-8 Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. WB:WBGene00004399 rol-9 No description available WB:WBGene00004400 rom-1 Predicted to enable serine-type endopeptidase activity. Involved in positive regulation of vulval development. Predicted to be located in membrane. Expressed in several structures, including head and tail. Is an ortholog of human RHBDL1 (rhomboid like 1) and RHBDL3 (rhomboid like 3). WB:WBGene00004401 rom-2 Predicted to enable serine-type endopeptidase activity. Predicted to be located in membrane. Is an ortholog of human RHBDL3 (rhomboid like 3). WB:WBGene00004402 rom-3 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in regulation of epidermal growth factor receptor signaling pathway and regulation of protein secretion. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in palmoplantar keratoderma-esophageal carcinoma syndrome. Is an ortholog of human RHBDF1 (rhomboid 5 homolog 1) and RHBDF2 (rhomboid 5 homolog 2). WB:WBGene00004403 rom-4 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in regulation of epidermal growth factor receptor signaling pathway and regulation of protein secretion. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in palmoplantar keratoderma-esophageal carcinoma syndrome. Is an ortholog of human RHBDF1 (rhomboid 5 homolog 1) and RHBDF2 (rhomboid 5 homolog 2). WB:WBGene00004404 rom-5 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in signal peptide processing. Predicted to be located in membrane. WB:WBGene00004405 rop-1 Predicted to enable RNA binding activity. Predicted to be located in cytoplasm. Predicted to be part of ribonucleoprotein complex. Expressed in several structures, including intestine and neurons. Is an ortholog of human RO60 (Ro60, Y RNA binding protein). WB:WBGene00004406 rot-1 No description available WB:WBGene00004407 rot-3 No description available WB:WBGene00004408 rla-0 Predicted to enable large ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal large subunit assembly. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in somatic cell and tail. Is an ortholog of human RPLP0 (ribosomal protein lateral stalk subunit P0) and RPLP0P6 (ribosomal protein lateral stalk subunit P0 pseudogene 6). WB:WBGene00004409 rla-1 Predicted to enable protein kinase activator activity and ribonucleoprotein complex binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in cytosolic ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPLP1 (ribosomal protein lateral stalk subunit P1). WB:WBGene00004410 rla-2 Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translational elongation. Predicted to be located in cytosolic ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in body wall musculature and intestine. Is an ortholog of human RPLP2 (ribosomal protein lateral stalk subunit P2). WB:WBGene00004411 rpc-1 Predicted to enable DNA binding activity and DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nuclear lumen. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in Wiedemann-Rautenstrauch syndrome and hypomyelinating leukodystrophy 7. Is an ortholog of human POLR3A (RNA polymerase III subunit A). WB:WBGene00004412 rpl-1 Predicted to enable RNA binding activity. Predicted to be involved in maturation of LSU-rRNA. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL10A (ribosomal protein L10a). WB:WBGene00004413 rpl-2 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL8 (ribosomal protein L8). WB:WBGene00004414 rpl-3 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2D. Is an ortholog of human RPL3 (ribosomal protein L3). WB:WBGene00004415 rpl-4 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL4 (ribosomal protein L4). WB:WBGene00004416 rpl-5 Predicted to enable 5S rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal large subunit assembly. Predicted to be located in cytoplasm; nucleus; and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in hyp7 syncytium; intestine; and pharyngeal cell. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 6; T-cell acute lymphoblastic leukemia; and glioblastoma. Is an ortholog of human RPL5 (ribosomal protein L5). WB:WBGene00004417 rpl-6 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in cytosol; ribosome; and rough endoplasmic reticulum. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL6 (ribosomal protein L6). WB:WBGene00004418 rpl-7 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in somatic cell. Is an ortholog of human RPL7 (ribosomal protein L7). WB:WBGene00004419 rpl-7A Enables calmodulin binding activity. Predicted to be involved in maturation of LSU-rRNA. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL7A (ribosomal protein L7a). WB:WBGene00004420 rpl-9 Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in intestine and tail. Is an ortholog of human RPL9 (ribosomal protein L9). WB:WBGene00004421 rpl-10 Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal large subunit assembly. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in head; pharyngeal muscle cell; and tail. Human ortholog(s) of this gene implicated in autistic disorder; spermatogenic failure 63; and syndromic X-linked mental retardation 35. Is an ortholog of human RPL10 (ribosomal protein L10) and RPL10L (ribosomal protein L10 like). WB:WBGene00004422 rpl-11.1 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasm; nucleus; and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in germ line. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 7 and T-cell acute lymphoblastic leukemia. Is an ortholog of human RPL11 (ribosomal protein L11). WB:WBGene00004423 rpl-11.2 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasm; nucleus; and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in embryonic cell; head; posterior gonad arm; and tail. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 7 and T-cell acute lymphoblastic leukemia. Is an ortholog of human RPL11 (ribosomal protein L11). WB:WBGene00004424 rpl-12 Predicted to enable large ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in intestine. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Is an ortholog of human RPL12 (ribosomal protein L12). WB:WBGene00004425 rpl-13 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytosol. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL13 (ribosomal protein L13). WB:WBGene00004426 rpl-14 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Is an ortholog of human RPL14 (ribosomal protein L14). WB:WBGene00004427 rpl-15 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 12. Is an ortholog of human RPL15 (ribosomal protein L15). WB:WBGene00004428 rpl-16 Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in negative regulation of translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL13A (ribosomal protein L13a). WB:WBGene00004429 rpl-17 Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL17 (ribosomal protein L17). WB:WBGene00004430 rpl-18 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 18. Is an ortholog of human RPL18 (ribosomal protein L18). WB:WBGene00004431 rpl-19 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL19 (ribosomal protein L19). WB:WBGene00004432 rpl-20 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL18A (ribosomal protein L18a). WB:WBGene00004433 rpl-21 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in hypotrichosis 12. Is an ortholog of human RPL21 (ribosomal protein L21). WB:WBGene00004434 rpl-22 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human RPL22 (ribosomal protein L22). WB:WBGene00004435 rpl-23 Predicted to enable large ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL23 (ribosomal protein L23). WB:WBGene00004436 rpl-24.1 Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL24 (ribosomal protein L24). WB:WBGene00004437 rpl-24.2 Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in nucleolus. Is an ortholog of human RSL24D1 (ribosomal L24 domain containing 1). WB:WBGene00004438 rpl-25.1 Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal large subunit assembly. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL23A (ribosomal protein L23a). WB:WBGene00004439 rpl-25.2 Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal large subunit assembly. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL23A (ribosomal protein L23a). WB:WBGene00004440 rpl-26 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal large subunit biogenesis. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 11. Is an ortholog of human RPL26 (ribosomal protein L26) and RPL26L1 (ribosomal protein L26 like 1). WB:WBGene00004441 rpl-27 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasmic side of rough endoplasmic reticulum membrane. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Is an ortholog of human RPL27 (ribosomal protein L27). WB:WBGene00004442 rpl-28 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL28 (ribosomal protein L28). WB:WBGene00004443 rpl-29 Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL29 (ribosomal protein L29). WB:WBGene00004444 rpl-30 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in herpes simplex. Is an ortholog of human RPL30 (ribosomal protein L30). WB:WBGene00004445 rpl-31 Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL31 (ribosomal protein L31). WB:WBGene00004446 rpl-32 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL32 (ribosomal protein L32). WB:WBGene00004447 rpl-33 Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal large subunit biogenesis. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 5 and glioblastoma. Is an ortholog of human RPL35A (ribosomal protein L35a). WB:WBGene00004448 rpl-34 Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosome biogenesis. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL34 (ribosomal protein L34). WB:WBGene00004449 rpl-35 Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 19. Is an ortholog of human RPL35 (ribosomal protein L35). WB:WBGene00004450 rpl-36 Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in cytosol and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL36 (ribosomal protein L36). WB:WBGene00004451 rpl-37 Predicted to enable RNA binding activity. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL37 (ribosomal protein L37). WB:WBGene00004452 rpl-38 Predicted to be a structural constituent of ribosome. Predicted to be involved in protein-RNA complex assembly. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL38 (ribosomal protein L38). WB:WBGene00004453 rpl-39 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL39 (ribosomal protein L39) and RPL39P5 (ribosomal protein L39 pseudogene 5). WB:WBGene00004454 rpl-36.A Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL36A (ribosomal protein L36a) and RPL36AL (ribosomal protein L36a like). WB:WBGene00004455 rpl-42 Enriched in AVK; germ line; and neurons based on RNA-seq studies. Is affected by several genes including rrf-3; pgl-1; and aak-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Tunicamycin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00004456 rpl-43 Predicted to enable metal ion binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL37A (ribosomal protein L37a). WB:WBGene00004457 rpm-1 Enables mitogen-activated protein kinase kinase kinase binding activity; protein phosphatase binding activity; and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of intracellular signal transduction; regulation of neuron projection development; and regulation of synapse assembly. Located in axon; neuromuscular junction; and presynaptic periactive zone. Expressed in several structures, including coelomocyte; hermaphrodite distal tip cell; nerve ring; pharynx; and touch receptor neurons. Is an ortholog of human MYCBP2 (MYC binding protein 2). WB:WBGene00004458 rpn-1 Predicted to enable enzyme regulator activity. Involved in nematode larval development and reproduction. Predicted to be located in nucleus and proteasome storage granule. Predicted to be part of proteasome regulatory particle, base subcomplex. Is an ortholog of human PSMD2 (proteasome 26S subunit ubiquitin receptor, non-ATPase 2). WB:WBGene00004459 rpn-2 Enables protein kinase C binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in several cellular components, including cell cortex; mitotic spindle; and nuclear membrane. Expressed in intestine. Is an ortholog of human PSMD1 (proteasome 26S subunit, non-ATPase 1). WB:WBGene00004460 rpn-3 Predicted to enable enzyme regulator activity. Involved in programmed cell death involved in cell development. Predicted to be part of proteasome regulatory particle, lid subcomplex. Expressed in head; intestine; and tail. Is an ortholog of human PSMD3 (proteasome 26S subunit, non-ATPase 3). WB:WBGene00004461 rpn-5 Predicted to be located in cytoplasm. Predicted to be part of proteasome regulatory particle, lid subcomplex. Is an ortholog of human PSMD12 (proteasome 26S subunit, non-ATPase 12). WB:WBGene00004462 rpn-6.1 Predicted to enable structural molecule activity. Involved in determination of adult lifespan; proteasome assembly; and ubiquitin-dependent protein catabolic process. Located in nucleus. Expressed in intestine and pharynx. Is an ortholog of human PSMD11 (proteasome 26S subunit, non-ATPase 11). WB:WBGene00004463 rpn-7 Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome regulatory particle. Expressed in tail. Is an ortholog of human PSMD6 (proteasome 26S subunit, non-ATPase 6). WB:WBGene00004464 rpn-8 Predicted to enable metallopeptidase activity. Involved in programmed cell death involved in cell development. Predicted to be part of proteasome complex. Is an ortholog of human PSMD7 (proteasome 26S subunit, non-ATPase 7). WB:WBGene00004465 rpn-9 Predicted to enable structural molecule activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of proteasome regulatory particle, lid subcomplex. Is an ortholog of human PSMD13 (proteasome 26S subunit, non-ATPase 13). WB:WBGene00004466 rpn-10 Predicted to enable polyubiquitin modification-dependent protein binding activity. Involved in spermatogenesis and ubiquitin-dependent protein catabolic process. Located in cytoplasm and nucleus. Expressed in several structures, including excretory cell; gonad; intestine; pharynx; and vulva. Is an ortholog of human PSMD4 (proteasome 26S subunit ubiquitin receptor, non-ATPase 4). WB:WBGene00004467 rpn-11 Predicted to enable metallopeptidase activity and proteasome binding activity. Involved in programmed cell death involved in cell development. Predicted to be part of proteasome regulatory particle, lid subcomplex. Is an ortholog of human PSMD14 (proteasome 26S subunit, non-ATPase 14). WB:WBGene00004468 rpn-12 Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome regulatory particle, lid subcomplex. Is an ortholog of human PSMD8 (proteasome 26S subunit, non-ATPase 8). WB:WBGene00004469 rps-0 Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal small subunit assembly. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic small ribosomal subunit. Expressed in tail. Is an ortholog of human RPSA (ribosomal protein SA). WB:WBGene00004470 rps-1 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytosol. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS3A (ribosomal protein S3A). WB:WBGene00004471 rps-2 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS2 (ribosomal protein S2). WB:WBGene00004472 rps-3 Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of apoptotic signaling pathway. Predicted to be located in nucleus. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS3 (ribosomal protein S3). WB:WBGene00004473 rps-4 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS4X (ribosomal protein S4 X-linked); RPS4Y1 (ribosomal protein S4 Y-linked 1); and RPS4Y2 (ribosomal protein S4 Y-linked 2). WB:WBGene00004474 rps-5 Predicted to enable mRNA binding activity and rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit assembly and translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit and small-subunit processome. Is an ortholog of human RPS5 (ribosomal protein S5). WB:WBGene00004475 rps-6 Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in cytoplasm; nucleolus; and ribosome. Predicted to be part of small-subunit processome. Is an ortholog of human RPS6 (ribosomal protein S6). WB:WBGene00004476 rps-7 Predicted to be a structural constituent of ribosome. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit and small-subunit processome. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 8. Is an ortholog of human RPS7 (ribosomal protein S7). WB:WBGene00004477 rps-8 Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in cytoplasm; intracellular non-membrane-bounded organelle; and membrane. Predicted to be part of cytosolic small ribosomal subunit and small-subunit processome. Is an ortholog of human RPS8 (ribosomal protein S8). WB:WBGene00004478 rps-9 Predicted to enable rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in cytoplasm; nucleolus; and ribosome. Predicted to be part of cytosolic small ribosomal subunit and small-subunit processome. Is an ortholog of human RPS9 (ribosomal protein S9). WB:WBGene00004479 rps-10 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 9. Is an ortholog of human RPS10 (ribosomal protein S10) and RPS10P5 (ribosomal protein S10 pseudogene 5). WB:WBGene00004480 rps-11 Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS11 (ribosomal protein S11). WB:WBGene00004481 rps-12 Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in nucleolus and ribosome. Predicted to be part of cytosolic small ribosomal subunit and small-subunit processome. Is an ortholog of human RPS12 (ribosomal protein S12). WB:WBGene00004482 rps-13 Predicted to enable small ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of cytosolic small ribosomal subunit and small-subunit processome. Is an ortholog of human RPS13 (ribosomal protein S13). WB:WBGene00004483 rps-14 Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit assembly and translation. Predicted to be located in cytoplasm; nucleolus; and ribosome. Predicted to be part of cytosolic small ribosomal subunit and small-subunit processome. Expressed in tail. Human ortholog(s) of this gene implicated in chromosome 5q deletion syndrome. Is an ortholog of human RPS14 (ribosomal protein S14). WB:WBGene00004484 rps-15 Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS15 (ribosomal protein S15). WB:WBGene00004485 rps-16 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS16 (ribosomal protein S16). WB:WBGene00004486 rps-17 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 4. Is an ortholog of human RPS17 (ribosomal protein S17). WB:WBGene00004487 rps-18 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytosol. Predicted to be part of small ribosomal subunit. Is an ortholog of human RPS18 (ribosomal protein S18). WB:WBGene00004488 rps-19 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit assembly. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 1. Is an ortholog of human RPS19 (ribosomal protein S19). WB:WBGene00004489 rps-20 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS20 (ribosomal protein S20). WB:WBGene00004490 rps-21 Predicted to be a structural constituent of ribosome. Predicted to be involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in cytosol; ribosome; and rough endoplasmic reticulum. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS21 (ribosomal protein S21). WB:WBGene00004491 rps-22 Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 20. Is an ortholog of human RPS15A (ribosomal protein S15a). WB:WBGene00004492 rps-23 Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit and polysomal ribosome. Human ortholog(s) of this gene implicated in brachycephaly, trichomegaly, and developmental delay. Is an ortholog of human RPS23 (ribosomal protein S23). WB:WBGene00004493 rps-24 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in Diamond-blackfan anemia 3. Is an ortholog of human RPS24 (ribosomal protein S24). WB:WBGene00004494 rps-25 Predicted to be a structural constituent of ribosome. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS25 (ribosomal protein S25). WB:WBGene00004495 rps-26 Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in cytoplasmic side of rough endoplasmic reticulum membrane. Predicted to be part of cytosolic small ribosomal subunit and polysomal ribosome. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 10. Is an ortholog of human RPS26 (ribosomal protein S26). WB:WBGene00004496 rps-27 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit assembly. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 17. Is an ortholog of human RPS27 (ribosomal protein S27). WB:WBGene00004497 rps-28 Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation; maturation of SSU-rRNA; and ribosomal small subunit assembly. Predicted to be located in cytoplasmic side of rough endoplasmic reticulum membrane. Predicted to be part of cytosolic small ribosomal subunit and polysomal ribosome. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 15 with mandibulofacial dysostosis. Is an ortholog of human RPS28 (ribosomal protein S28). WB:WBGene00004498 rps-29 Predicted to enable zinc ion binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 13. Is an ortholog of human RPS29 (ribosomal protein S29). WB:WBGene00004499 rps-30 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human FAU (FAU ubiquitin like and ribosomal protein S30 fusion). WB:WBGene00004501 rpt-1 Predicted to enable proteasome-activating activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome regulatory particle, base subcomplex. Is an ortholog of human PSMC2 (proteasome 26S subunit, ATPase 2). WB:WBGene00004502 rpt-2 Enables ubiquitin protein ligase binding activity. Involved in negative regulation of gene expression. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome regulatory particle, base subcomplex. Expressed in head. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with poor growth, spastic tetraplegia, and hearing loss. Is an ortholog of human PSMC1 (proteasome 26S subunit, ATPase 1). WB:WBGene00004503 rpt-3 Predicted to enable proteasome-activating activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome regulatory particle, base subcomplex. Is an ortholog of human PSMC4 (proteasome 26S subunit, ATPase 4). WB:WBGene00004504 rpt-4 Enables identical protein binding activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of protein stability. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cytosolic proteasome complex and proteasome regulatory particle, base subcomplex. Is an ortholog of human PSMC6 (proteasome 26S subunit, ATPase 6). WB:WBGene00004505 rpt-5 Predicted to enable proteasome-activating activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome regulatory particle, base subcomplex. Expressed in head and tail. Used to study obesity. Is an ortholog of human PSMC3 (proteasome 26S subunit, ATPase 3). WB:WBGene00004506 rpt-6 Predicted to enable proteasome-activating activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome regulatory particle, base subcomplex. Is an ortholog of human PSMC5 (proteasome 26S subunit, ATPase 5). WB:WBGene00004507 rpy-1 Predicted to enable acetylcholine receptor binding activity. Predicted to be involved in cholinergic synaptic transmission and positive regulation of neuromuscular synaptic transmission. Predicted to be located in neuromuscular junction and plasma membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 11 and fetal akinesia deformation sequence syndrome 2. Is an ortholog of human RAPSN (receptor associated protein of the synapse). WB:WBGene00004508 rrf-1 Enables DEAD/H-box RNA helicase binding activity and RNA-dependent RNA polymerase activity. Involved in siRNA processing. Located in mutator focus and nucleus. Part of polysome. WB:WBGene00004509 rrf-2 Predicted to enable RNA-dependent RNA polymerase activity. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be part of nuclear RNA-directed RNA polymerase complex. WB:WBGene00004510 rrf-3 Predicted to enable RNA-dependent RNA polymerase activity. Involved in regulatory ncRNA-mediated heterochromatin formation and spermatogenesis. Predicted to be part of nuclear RNA-directed RNA polymerase complex. Expressed in head and tail. WB:WBGene00004511 rrn-1 No description available WB:WBGene00004512 rrn-1.1 Enriched in distal tip cell; germ line; and neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; aak-2; and unc-30 based on RNA-seq and microarray studies. Is affected by Ethanol; multi-walled carbon nanotube; and Ketamine based on RNA-seq studies. WB:WBGene00004513 rrn-1.2 Is affected by several genes including daf-16; daf-12; and aak-2 based on RNA-seq studies. Is affected by Ethanol; multi-walled carbon nanotube; and Ketamine based on RNA-seq studies. WB:WBGene00004514 rrn-1.3 No description available WB:WBGene00004515 rrn-1.4 No description available WB:WBGene00004516 rrn-1.5 No description available WB:WBGene00004517 rrn-1.6 No description available WB:WBGene00004518 rrn-1.7 No description available WB:WBGene00004519 rrn-1.8 No description available WB:WBGene00004520 rrn-1.9 No description available WB:WBGene00004521 rrn-1.10 No description available WB:WBGene00004522 rrn-1.11 No description available WB:WBGene00004523 rrn-1.12 No description available WB:WBGene00004524 rrn-1.13 No description available WB:WBGene00004525 rrn-1.14 No description available WB:WBGene00004526 rrn-1.15 No description available WB:WBGene00004527 rrn-1.16 No description available WB:WBGene00004528 rrn-1.17 No description available WB:WBGene00004529 rrn-1.18 No description available WB:WBGene00004530 rrn-1.19 No description available WB:WBGene00004531 rrn-1.20 No description available WB:WBGene00004532 rrn-1.21 No description available WB:WBGene00004533 rrn-1.22 No description available WB:WBGene00004534 rrn-1.23 No description available WB:WBGene00004535 rrn-1.24 No description available WB:WBGene00004536 rrn-1.25 No description available WB:WBGene00004537 rrn-1.26 No description available WB:WBGene00004538 rrn-1.27 No description available WB:WBGene00004539 rrn-1.28 No description available WB:WBGene00004540 rrn-1.29 No description available WB:WBGene00004541 rrn-1.30 No description available WB:WBGene00004542 rrn-1.31 No description available WB:WBGene00004543 rrn-1.32 No description available WB:WBGene00004544 rrn-1.33 No description available WB:WBGene00004545 rrn-1.34 No description available WB:WBGene00004546 rrn-1.35 No description available WB:WBGene00004547 rrn-1.36 No description available WB:WBGene00004548 rrn-1.37 No description available WB:WBGene00004549 rrn-1.38 No description available WB:WBGene00004550 rrn-1.39 No description available WB:WBGene00004551 rrn-1.40 No description available WB:WBGene00004552 rrn-1.41 No description available WB:WBGene00004553 rrn-1.42 No description available WB:WBGene00004554 rrn-1.43 No description available WB:WBGene00004555 rrn-1.44 No description available WB:WBGene00004556 rrn-1.45 No description available WB:WBGene00004557 rrn-1.46 No description available WB:WBGene00004558 rrn-1.47 No description available WB:WBGene00004559 rrn-1.48 No description available WB:WBGene00004560 rrn-1.49 No description available WB:WBGene00004561 rrn-1.50 No description available WB:WBGene00004562 rrn-1.51 No description available WB:WBGene00004563 rrn-1.52 No description available WB:WBGene00004564 rrn-1.53 No description available WB:WBGene00004565 rrn-1.54 No description available WB:WBGene00004566 rrn-1.55 No description available WB:WBGene00004567 rrn-2.1 Enriched in I4 neuron; PDB; distal tip cell; excretory gland cell; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and npr-1 based on RNA-seq studies. Is affected by nine chemicals including Ethanol; Nitric Oxide; and 1-methylnicotinamide based on RNA-seq studies. WB:WBGene00004568 rrn-2.2 No description available WB:WBGene00004569 rrn-2.3 No description available WB:WBGene00004570 rrn-2.4 No description available WB:WBGene00004571 rrn-2.5 No description available WB:WBGene00004572 rrn-2.6 No description available WB:WBGene00004573 rrn-2.7 No description available WB:WBGene00004574 rrn-2.8 No description available WB:WBGene00004575 rrn-2.9 No description available WB:WBGene00004576 rrn-2.10 No description available WB:WBGene00004577 rrn-2.11 No description available WB:WBGene00004578 rrn-2.12 No description available WB:WBGene00004579 rrn-2.13 No description available WB:WBGene00004580 rrn-2.14 No description available WB:WBGene00004581 rrn-2.15 No description available WB:WBGene00004582 rrn-2.16 No description available WB:WBGene00004583 rrn-2.17 No description available WB:WBGene00004584 rrn-2.18 No description available WB:WBGene00004585 rrn-2.19 No description available WB:WBGene00004586 rrn-2.20 No description available WB:WBGene00004587 rrn-2.21 No description available WB:WBGene00004588 rrn-2.22 No description available WB:WBGene00004589 rrn-2.23 No description available WB:WBGene00004590 rrn-2.24 No description available WB:WBGene00004591 rrn-2.25 No description available WB:WBGene00004592 rrn-2.26 No description available WB:WBGene00004593 rrn-2.27 No description available WB:WBGene00004594 rrn-2.28 No description available WB:WBGene00004595 rrn-2.29 No description available WB:WBGene00004596 rrn-2.30 No description available WB:WBGene00004597 rrn-2.31 No description available WB:WBGene00004598 rrn-2.32 No description available WB:WBGene00004599 rrn-2.33 No description available WB:WBGene00004600 rrn-2.34 No description available WB:WBGene00004601 rrn-2.35 No description available WB:WBGene00004602 rrn-2.36 No description available WB:WBGene00004603 rrn-2.37 No description available WB:WBGene00004604 rrn-2.38 No description available WB:WBGene00004605 rrn-2.39 No description available WB:WBGene00004606 rrn-2.40 No description available WB:WBGene00004607 rrn-2.41 No description available WB:WBGene00004608 rrn-2.42 No description available WB:WBGene00004609 rrn-2.43 No description available WB:WBGene00004610 rrn-2.44 No description available WB:WBGene00004611 rrn-2.45 No description available WB:WBGene00004612 rrn-2.46 No description available WB:WBGene00004613 rrn-2.47 No description available WB:WBGene00004614 rrn-2.48 No description available WB:WBGene00004615 rrn-2.49 No description available WB:WBGene00004616 rrn-2.50 No description available WB:WBGene00004617 rrn-2.51 No description available WB:WBGene00004618 rrn-2.52 No description available WB:WBGene00004619 rrn-2.53 No description available WB:WBGene00004620 rrn-2.54 No description available WB:WBGene00004621 rrn-2.55 No description available WB:WBGene00004622 rrn-3.1 Enriched in excretory cell; germ line; intestine; and neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; npr-1; and aak-2 based on RNA-seq studies. Is affected by six chemicals including rotenone; multi-walled carbon nanotube; and sesamin based on RNA-seq and microarray studies. WB:WBGene00004623 rrn-3.2 No description available WB:WBGene00004624 rrn-3.3 No description available WB:WBGene00004625 rrn-3.4 No description available WB:WBGene00004626 rrn-3.5 No description available WB:WBGene00004627 rrn-3.6 No description available WB:WBGene00004628 rrn-3.7 No description available WB:WBGene00004629 rrn-3.8 No description available WB:WBGene00004630 rrn-3.9 No description available WB:WBGene00004631 rrn-3.10 No description available WB:WBGene00004632 rrn-3.11 No description available WB:WBGene00004633 rrn-3.12 No description available WB:WBGene00004634 rrn-3.13 No description available WB:WBGene00004635 rrn-3.14 No description available WB:WBGene00004636 rrn-3.15 No description available WB:WBGene00004637 rrn-3.16 No description available WB:WBGene00004638 rrn-3.17 No description available WB:WBGene00004639 rrn-3.18 No description available WB:WBGene00004640 rrn-3.19 No description available WB:WBGene00004641 rrn-3.20 No description available WB:WBGene00004642 rrn-3.21 No description available WB:WBGene00004643 rrn-3.22 No description available WB:WBGene00004644 rrn-3.23 No description available WB:WBGene00004645 rrn-3.24 No description available WB:WBGene00004646 rrn-3.25 No description available WB:WBGene00004647 rrn-3.26 No description available WB:WBGene00004648 rrn-3.27 No description available WB:WBGene00004649 rrn-3.28 No description available WB:WBGene00004650 rrn-3.29 No description available WB:WBGene00004651 rrn-3.30 No description available WB:WBGene00004652 rrn-3.31 No description available WB:WBGene00004653 rrn-3.32 No description available WB:WBGene00004654 rrn-3.33 No description available WB:WBGene00004655 rrn-3.34 No description available WB:WBGene00004656 rrn-3.35 No description available WB:WBGene00004657 rrn-3.36 No description available WB:WBGene00004658 rrn-3.37 No description available WB:WBGene00004659 rrn-3.38 No description available WB:WBGene00004660 rrn-3.39 No description available WB:WBGene00004661 rrn-3.40 No description available WB:WBGene00004662 rrn-3.41 No description available WB:WBGene00004663 rrn-3.42 No description available WB:WBGene00004664 rrn-3.43 No description available WB:WBGene00004665 rrn-3.44 No description available WB:WBGene00004666 rrn-3.45 No description available WB:WBGene00004667 rrn-3.46 No description available WB:WBGene00004668 rrn-3.47 No description available WB:WBGene00004669 rrn-3.48 No description available WB:WBGene00004670 rrn-3.49 No description available WB:WBGene00004671 rrn-3.50 No description available WB:WBGene00004672 rrn-3.51 No description available WB:WBGene00004673 rrn-3.52 No description available WB:WBGene00004674 rrn-3.53 No description available WB:WBGene00004675 rrn-3.54 No description available WB:WBGene00004676 rrn-3.55 No description available WB:WBGene00004677 rrn-3.56 Enriched in DA neuron; MC neuron; cephalic sheath cell; and command interneuron based on single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and npr-1 based on RNA-seq studies. Is affected by eight chemicals including rotenone; multi-walled carbon nanotube; and allantoin based on RNA-seq studies. WB:WBGene00004678 rrs-1 No description available WB:WBGene00004679 rars-1 Predicted to enable arginine-tRNA ligase activity. Involved in determination of adult lifespan; regulation of gene expression; and translation. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 9. Is an ortholog of human RARS1 (arginyl-tRNA synthetase 1). WB:WBGene00004680 rars-2 Predicted to enable arginine-tRNA ligase activity. Predicted to be involved in arginyl-tRNA aminoacylation and mitochondrial translation. Predicted to be located in mitochondrion. Expressed in body wall musculature and pharynx. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 6. Is an ortholog of human RARS2 (arginyl-tRNA synthetase 2, mitochondrial). WB:WBGene00004681 rsd-2 Located in cytoplasm and nucleolus. Expressed in germ cell. WB:WBGene00004682 rsd-3 Predicted to enable clathrin binding activity and phospholipid binding activity. Predicted to be involved in endocytosis. Predicted to be located in endosome and plasma membrane. Predicted to be part of clathrin vesicle coat. Expressed in several structures, including body wall musculature; coelomocyte; excretory canal; intestine; and pharynx. Is an ortholog of human CLINT1 (clathrin interactor 1). WB:WBGene00004683 rsd-4 No description available WB:WBGene00004684 rsd-6 Predicted to be involved in P granule organization; piRNA processing; and spermatogenesis. Located in cytoplasm. WB:WBGene00004685 rsn-1 No description available WB:WBGene00004686 rsn-2 No description available WB:WBGene00004687 rsn-3 No description available WB:WBGene00004688 rsn-4 No description available WB:WBGene00004689 rsn-5 No description available WB:WBGene00004690 rsn-6 No description available WB:WBGene00004691 rsn-7 No description available WB:WBGene00004692 rsn-8 No description available WB:WBGene00004693 rsn-9 No description available WB:WBGene00004694 rsn-10 No description available WB:WBGene00004695 rsn-11 No description available WB:WBGene00004696 rsn-12 No description available WB:WBGene00004697 rsn-13 No description available WB:WBGene00004698 rsp-1 Predicted to enable RNA binding activity. Involved in gonad development; regulation of growth rate; and spermatogenesis. Located in nucleus. Expressed in several structures, including intestine and pharyngeal neurons. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; Huntington's disease; and carcinoma (multiple). Is an ortholog of human SRSF5 (serine and arginine rich splicing factor 5) and SRSF6 (serine and arginine rich splicing factor 6). WB:WBGene00004699 rsp-2 Predicted to enable RNA binding activity. Involved in developmental process involved in reproduction; nematode larval development; and regulation of growth rate. Located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; carcinoma (multiple); and proliferative diabetic retinopathy. Is an ortholog of human SRSF5 (serine and arginine rich splicing factor 5) and SRSF6 (serine and arginine rich splicing factor 6). WB:WBGene00004700 rsp-3 Predicted to enable RNA binding activity. Involved in embryo development. Predicted to be located in nuclear speck. Expressed in PVDL; PVDR; and gonad. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); lung non-small cell carcinoma (multiple); and urinary system cancer (multiple). Is an ortholog of human SRSF1 (serine and arginine rich splicing factor 1). WB:WBGene00004701 rsp-4 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); and lung cancer (multiple). Is an ortholog of human SRSF2 (serine and arginine rich splicing factor 2). WB:WBGene00004702 rsp-5 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed widely. WB:WBGene00004703 rsp-6 Predicted to enable mRNA binding activity. Involved in gonad development and regulation of termination of DNA-templated transcription. Located in nucleus. Expressed in several structures, including PVDL and PVDR. Human ortholog(s) of this gene implicated in bipolar disorder; clear cell renal cell carcinoma; and ovary epithelial cancer. Is an ortholog of human SRSF7 (serine and arginine rich splicing factor 7). WB:WBGene00004704 rsp-7 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Human ortholog(s) of this gene implicated in autism spectrum disorder and myelodysplastic syndrome. Is an ortholog of human SREK1 (splicing regulatory glutamic acid and lysine rich protein 1). WB:WBGene00004705 rsp-8 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome and positive regulation of mRNA splicing, via spliceosome. Predicted to be part of spliceosomal complex. Expressed in head and tail. Human ortholog(s) of this gene implicated in macular degeneration. Is an ortholog of human TRA2A (transformer 2 alpha homolog) and TRA2B (transformer 2 beta homolog). WB:WBGene00004706 rsr-1 Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Expressed in hypodermis. Human ortholog(s) of this gene implicated in gestational diabetes. Is an ortholog of human SRRM1 (serine and arginine repetitive matrix 1). WB:WBGene00004708 rte-1 No description available WB:WBGene00004709 rtm-1 No description available WB:WBGene00004710 rtm-2 No description available WB:WBGene00004711 rtm-3 No description available WB:WBGene00004712 rtm-4 No description available WB:WBGene00004713 rtr-1 No description available WB:WBGene00004714 rtu-1 No description available WB:WBGene00004715 rtw-3 No description available WB:WBGene00004716 rtw-5 No description available WB:WBGene00004717 rtw-6 No description available WB:WBGene00004718 rtw-7 No description available WB:WBGene00004719 sad-1 Enables protein kinase activity. Involved in cellular component organization; cellular localization; and establishment or maintenance of cell polarity. Located in axon and dendrite. Expressed in nervous system. Is an ortholog of human BRSK1 (BR serine/threonine kinase 1) and BRSK2 (BR serine/threonine kinase 2). WB:WBGene00004721 san-1 Predicted to enable protein kinase activity. Involved in mitotic spindle assembly checkpoint signaling and response to anoxia. Located in kinetochore and nucleoplasm. WB:WBGene00004723 sap-49 Predicted to enable RNA binding activity. Predicted to be involved in positive regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U12-type spliceosomal complex and U2 snRNP. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in Nager acrofacial dysostosis; cervical cancer; and endocrine gland cancer (multiple). Is an ortholog of human SF3B4 (splicing factor 3b subunit 4). WB:WBGene00004725 sas-2 No description available WB:WBGene00004726 sas-4 Involved in centriole replication and maintenance of protein location. Located in centriole. Expressed in gonad; intestinal cell; and sperm. WB:WBGene00004727 sax-1 Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including cell projection organization; negative regulation of cell growth; and regulation of cell shape. Located in cytoplasm; neuron projection; and nucleus. Expressed in hypodermis; muscle cell; nerve ring; and seam cell. Is an ortholog of human STK38 (serine/threonine kinase 38). WB:WBGene00004728 sax-2 Involved in neuron projection development. Predicted to be located in cell cortex and site of polarized growth. Expressed in head neurons; tail neurons; and ventral nerve cord. Is an ortholog of human FRY (FRY microtubule binding protein) and FRYL (FRY like transcription coactivator). WB:WBGene00004729 sax-3 Enables axon guidance receptor activity. Involved in generation of neurons and regulation of sensory neuron axon guidance. Located in plasma membrane. Expressed in several structures, including QR.a; QR.p; body wall musculature; neuroblasts; and neurons. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive congenital nystagmus; hematologic cancer (multiple); and myositis (multiple). Is an ortholog of human ROBO1 (roundabout guidance receptor 1); ROBO2 (roundabout guidance receptor 2); and ROBO3 (roundabout guidance receptor 3). WB:WBGene00004730 sax-5 No description available WB:WBGene00004731 sax-6 No description available WB:WBGene00004732 sax-7 Enables ankyrin binding activity. Involved in several processes, including cell development; establishment of mitotic spindle orientation; and regulation of cell morphogenesis. Located in several cellular components, including axolemma; lateral plasma membrane; and somatodendritic compartment. Expressed in several structures, including gonad; neurons; pharynx; somatic nervous system; and vulval cell. Used to study MASA syndrome. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human NFASC (neurofascin) and NRCAM (neuronal cell adhesion molecule). WB:WBGene00004734 sax-9 No description available WB:WBGene00004735 sbp-1 Enables DNA-binding transcription factor activity. Involved in several processes, including cellular response to zinc ion; fatty acid metabolic process; and positive regulation of macromolecule metabolic process. Located in nucleus. Expressed in several structures, including amphid neurons; head; intestine; and neurons. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including carotid artery disease; diabetes mellitus (multiple); and vascular dementia. Is an ortholog of human SREBF2 (sterol regulatory element binding transcription factor 2). WB:WBGene00004736 sca-1 Enables P-type calcium transporter activity and chromatin DNA binding activity. Involved in several processes, including IRE1-mediated unfolded protein response; calcium ion import; and chemical homeostasis. Located in cytoplasmic vesicle and endomembrane system. Expressed in several structures, including egg-laying apparatus; excretory system; intestine; non-striated muscle; and spermatheca. Human ortholog(s) of this gene implicated in Brody myopathy; hypertension (multiple); and keratosis (multiple). Is an ortholog of human ATP2A3 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3). WB:WBGene00004737 scc-1 Predicted to enable chromatin binding activity and damaged DNA binding activity. Involved in meiotic cell cycle. Located in nucleus. Part of cohesin complex. Expressed in several structures, including SDQ; germ line; seam cell; touch receptor neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 4; carcinoma (multiple); and endometrial cancer. Is an ortholog of human RAD21 (RAD21 cohesin complex component) and RAD21L1 (RAD21 cohesin complex component like 1). WB:WBGene00004738 scc-3 Predicted to enable DNA binding activity and chromatin binding activity. Involved in organelle organization and regulation of DNA damage checkpoint. Located in condensed chromosome. Part of chromatin and cohesin complex. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including intellectual disability (multiple); primary ovarian insufficiency 8; and spermatogenic failure 61. Is an ortholog of human STAG1 (STAG1 cohesin complex component) and STAG2 (STAG2 cohesin complex component). WB:WBGene00004739 scd-1 Enriched in several structures, including ABalppppppa; ABpraaapppa; head mesodermal cell; neurons; and pharyngeal cell based on Chronogram; microarray; RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including 1-methylnicotinamide; rotenone; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00004740 scd-2 Predicted to enable ATP binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in dauer larval development; sensory perception of chemical stimulus; and sensory processing. Predicted to be located in plasma membrane. Expressed in AIAL; AIAR; NSML; and NSMR. Is an ortholog of human ALK (ALK receptor tyrosine kinase) and LTK (leukocyte receptor tyrosine kinase). WB:WBGene00004741 scd-3 No description available WB:WBGene00004742 scl-1 Involved in determination of adult lifespan; response to UV; and response to heat. Predicted to be located in extracellular space. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00004743 scm-1 Predicted to be involved in protein transport. Located in cytoplasmic vesicle. Expressed in amphid neurons; coelomocyte; and spermatheca. Is an ortholog of human SCAMP1 (secretory carrier membrane protein 1) and SCAMP2 (secretory carrier membrane protein 2). WB:WBGene00004744 scp-1 Predicted to enable sterol binding activity. Predicted to be involved in regulation of cholesterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of SREBP-SCAP complex. Is an ortholog of human SCAP (SREBF chaperone). WB:WBGene00004745 sdc-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in regulation of macromolecule metabolic process and sex determination. Located in nuclear chromosome. WB:WBGene00004746 sdc-2 Involved in dosage compensation by hypoactivation of X chromosome and negative regulation of transcription by RNA polymerase II. Located in nuclear chromosome. WB:WBGene00004747 sdc-3 Enables sequence-specific DNA binding activity. Involved in several processes, including mitotic sister chromatid segregation; negative regulation of transcription by RNA polymerase II; and sex determination. Located in X chromosome and nucleus. Expressed in germ line and oocyte. WB:WBGene00004748 sdf-9 Predicted to enable protein tyrosine phosphatase activity. Involved in dauer larval development. Located in plasma membrane. Expressed in XXXL; XXXR; and head. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human PTPN1 (protein tyrosine phosphatase non-receptor type 1). WB:WBGene00004749 sdn-1 Involved in embryo development; epidermis morphogenesis; and nematode larval development. Located in cell surface. Expressed in several structures, including neuroblasts; neurons; pharynx; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Hodgkin's lymphoma; cleft lip; and glucose metabolism disease (multiple). Is an ortholog of human SDC1 (syndecan 1); SDC2 (syndecan 2); and SDC4 (syndecan 4). WB:WBGene00004750 sea-1 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in dosage compensation by hypoactivation of X chromosome; positive regulation of transcription by RNA polymerase II; and sex determination. Located in nucleus. Expressed in several structures, including coelomocyte; head muscle; intestine; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in Abruzzo-Erickson syndrome; X-linked cleft palate with or without ankyloglossia; and bone disease (multiple). Is an ortholog of several human genes including TBX15 (T-box transcription factor 15); TBX4 (T-box transcription factor 4); and TBX6 (T-box transcription factor 6). WB:WBGene00004751 sea-2 Enables double-stranded RNA binding activity and single-stranded RNA binding activity. Involved in several processes, including determination of adult lifespan; regulation of gene expression; and response to heat. Located in cytoplasm and nucleus. Expressed in intestinal cell; nerve ring neurons; neurons; pharyngeal muscle cell; and seam cell. WB:WBGene00004752 sec-5 Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to be part of exocyst. Expressed in anchor cell; embryonic cell; and excretory canal. Is an ortholog of human EXOC2 (exocyst complex component 2). WB:WBGene00004753 sec-8 Predicted to be involved in Golgi to plasma membrane transport; chemical synaptic transmission; and exocytosis. Predicted to be located in growth cone membrane and synapse. Predicted to be part of exocyst. Expressed in embryonic cell; excretory canal; and hypodermis. Is an ortholog of human EXOC4 (exocyst complex component 4). WB:WBGene00004754 sec-23 Predicted to enable GTPase activator activity. Predicted to be involved in COPII-coated vesicle cargo loading. Located in endoplasmic reticulum exit site. Expressed in hypodermis. Human ortholog(s) of this gene implicated in Cowden syndrome 7; congenital dyserythropoietic anemia type II; and craniolenticulosutural dysplasia. Is an ortholog of human SEC23B (SEC23 homolog B, COPII coat complex component). WB:WBGene00004755 sec-24.1 Predicted to enable SNARE binding activity and zinc ion binding activity. Predicted to be involved in COPII-coated vesicle cargo loading. Predicted to be located in endoplasmic reticulum exit site. Predicted to be part of COPII vesicle coat. Expressed widely. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Is an ortholog of human SEC24D (SEC24 homolog D, COPII coat complex component). WB:WBGene00004756 sec-24.2 Predicted to enable SNARE binding activity and zinc ion binding activity. Predicted to be involved in COPII-coated vesicle cargo loading. Predicted to be located in endoplasmic reticulum exit site. Predicted to be part of COPII vesicle coat. Expressed in DA neuron. Is an ortholog of human SEC24A (SEC24 homolog A, COPII coat complex component). WB:WBGene00004758 sek-1 Enables MAP kinase kinase activity; mitogen-activated protein kinase kinase kinase binding activity; and protein serine kinase activity. Involved in several processes, including defense response to other organism; p38MAPK cascade; and positive regulation of egg-laying behavior. Expressed in excretory canal; linker cell; neurons; rectal epithelium; and uterine-vulval cell. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in several diseases, including Pick's disease; female reproductive organ cancer (multiple); and progressive supranuclear palsy. Is an ortholog of human MAP2K3 (mitogen-activated protein kinase kinase 3) and MAP2K6 (mitogen-activated protein kinase kinase 6). WB:WBGene00004759 sel-1 Predicted to contribute to ubiquitin-protein transferase activity. Involved in negative regulation of Notch signaling pathway. Located in cytoplasmic vesicle. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P7.p hermaphrodite; and P8.p hermaphrodite. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human SEL1L (SEL1L adaptor subunit of SYVN1 ubiquitin ligase). WB:WBGene00004760 sel-2 Predicted to enable protein kinase binding activity. Involved in several processes, including apical protein localization; negative regulation of Notch signaling pathway; and regulation of vulval development. Located in perinuclear region of cytoplasm. Expressed in several structures, including ganglia; pharyngeal-intestinal valve; rectum; somatic nervous system; and vulva. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in common variable immunodeficiency 8 and stomach cancer. Is an ortholog of human LRBA (LPS responsive beige-like anchor protein) and NBEA (neurobeachin). WB:WBGene00004761 sel-4 No description available WB:WBGene00004762 sel-5 Predicted to enable AP-2 adaptor complex binding activity and protein serine/threonine kinase activity. Predicted to be involved in positive regulation of Notch signaling pathway and regulation of clathrin-dependent endocytosis. Predicted to be located in cytoplasm. Used to study Parkinson's disease. Is an ortholog of human AAK1 (AP2 associated kinase 1). WB:WBGene00004764 sel-7 Enables identical protein binding activity and sequence-specific DNA binding activity. Involved in several processes, including lateral inhibition; negative regulation of transcription by RNA polymerase II; and positive regulation of Notch signaling pathway. Located in nucleus. Expressed in body wall musculature; pharyngeal muscle cell; and seam cell. WB:WBGene00004765 sel-8 Enables DNA-binding transcription factor binding activity; Notch binding activity; and transcription coactivator activity. Involved in several processes, including Notch signaling pathway; positive regulation of stem cell proliferation; and regulation of mesodermal cell fate specification. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and neurons. WB:WBGene00004766 sel-9 Involved in endoplasmic reticulum to Golgi vesicle-mediated transport; regulation of Notch signaling pathway; and regulation of transport. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human TMED2 (transmembrane p24 trafficking protein 2). WB:WBGene00004767 sel-10 Enables protein homodimerization activity and protein kinase binding activity. Involved in several processes, including negative regulation of Notch signaling pathway; negative regulation of centrosome duplication; and regulation of vulval development. Located in axon and cytoplasm. Expressed in body wall musculature; gonad; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in developmental delay, hypotonia, and impaired language. Is an ortholog of human FBXW7 (F-box and WD repeat domain containing 7). WB:WBGene00004768 sel-11 Predicted to enable metal ion binding activity and transferase activity. Involved in regulation of Notch signaling pathway and regulation of gene expression. Predicted to be located in cytoplasm. Is an ortholog of human SYVN1 (synoviolin 1). WB:WBGene00004769 sel-12 Predicted to enable endopeptidase activity. Involved in several processes, including apical protein localization; egg-laying behavior; and regulation of signal transduction. Located in perinuclear region of cytoplasm. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 3; Alzheimer's disease 4; Pick's disease; dilated cardiomyopathy (multiple); and hidradenitis suppurativa. Is an ortholog of human PSEN1 (presenilin 1) and PSEN2 (presenilin 2). WB:WBGene00004770 sem-1 No description available WB:WBGene00004771 sem-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cell fate specification; positive regulation of developmental process; and positive regulation of egg-laying behavior. Located in nucleus. Expressed in several structures, including E lineage cell; M.v nucleus; RMH; body wall muscle cell from M lineage; and neuroblasts. Human ortholog(s) of this gene implicated in several diseases, including Coffin-Siris syndrome (multiple); hypotrichosis-lymphedema-telangiectasia syndrome; and hypotrichosis-lymphedema-telangiectasia-renal defect syndrome. Is an ortholog of several human genes including SOX11 (SRY-box transcription factor 11); SOX18 (SRY-box transcription factor 18); and SOX4 (SRY-box transcription factor 4). WB:WBGene00004772 sem-3 No description available WB:WBGene00004773 sem-4 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell differentiation; regulation of transcription by RNA polymerase II; and response to oxidative stress. Located in nucleus. Expressed in several structures, including HSN; M lineage cell; rectal epithelial cell; rectum; and tail hypodermis. Human ortholog(s) of this gene implicated in several diseases, including Duane retraction syndrome; Duane-radial ray syndrome; and Holt-Oram syndrome. Is an ortholog of human SALL1 (spalt like transcription factor 1) and SALL3 (spalt like transcription factor 3). WB:WBGene00004774 sem-5 Enables epidermal growth factor receptor binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; male genitalia development; and regulation of vulval development. Predicted to be located in cytoplasm; nucleoplasm; and plasma membrane. Predicted to be part of COP9 signalosome. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P7.p hermaphrodite; and P8.p hermaphrodite. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 114; breast cancer; and reproductive organ cancer (multiple). Is an ortholog of human GRB2 (growth factor receptor bound protein 2). WB:WBGene00004775 sep-1 Predicted to enable cysteine-type endopeptidase activity. Involved in several processes, including nuclear division; polarity specification of anterior/posterior axis; and sexual reproduction. Located in several cellular components, including intracellular membrane-bounded organelle; metaphase plate; and microtubule cytoskeleton. Is an ortholog of human ESPL1 (extra spindle pole bodies like 1, separase). WB:WBGene00004776 ser-1 Enables G protein-coupled serotonin receptor activity and serotonin binding activity. Involved in several processes, including reproductive behavior; response to heat; and signal transduction. Located in plasma membrane. Expressed in several structures, including egg-laying apparatus; intestine; neurons; pharyngeal muscle cell; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; anorexia nervosa; and obsessive-compulsive disorder. Is an ortholog of human HTR2A (5-hydroxytryptamine receptor 2A) and HTR2B (5-hydroxytryptamine receptor 2B). WB:WBGene00004777 ser-2 Enables tyramine receptor activity. Involved in octopamine or tyramine signaling pathway. Located in plasma membrane. Expressed in body wall musculature; excretory gland cell; neurons; non-striated muscle; and uterine toroidal epithelial cell. WB:WBGene00004778 ser-3 Enables octopamine receptor activity. Involved in octopamine or tyramine signaling pathway. Predicted to be located in dendrite. Expressed in several structures, including ASH; SIA; head muscle; hermaphrodite gonad; and lumbar ganglion. WB:WBGene00004779 ser-4 Enables G protein-coupled serotonin receptor activity. Involved in regulation of locomotion and serotonin receptor signaling pathway. Predicted to be located in dendrite. Expressed in neurons; vm2; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; attention deficit hyperactivity disorder; conduct disorder; and panic disorder. Is an ortholog of human HTR1A (5-hydroxytryptamine receptor 1A). WB:WBGene00004780 ser-7 Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Located in membrane. Expressed in pharyngeal neurons and vulval muscle. Human ortholog(s) of this gene implicated in alcohol use disorder. Is an ortholog of human HTR7 (5-hydroxytryptamine receptor 7). WB:WBGene00004781 set-1 Predicted to enable histone H4K20 methyltransferase activity. Involved in embryo development. Located in nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P7.p hermaphrodite; and P8.p hermaphrodite. Is an ortholog of human KMT5A (lysine methyltransferase 5A). WB:WBGene00004782 set-2 Enables histone H3K4 methyltransferase activity. Involved in determination of adult lifespan and transdifferentiation. Located in nucleus. Expressed in several structures, including germ line; hermaphrodite distal tip cell; intestine; and nerve ring. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with speech impairment and dysmorphic facies. Is an ortholog of human SETD1A (SET domain containing 1A, histone lysine methyltransferase). WB:WBGene00004783 seu-1 Involved in dorsal/ventral axon guidance. Located in nucleus. Expressed in several structures, including hermaphrodite distal tip cell; intestine; pharynx; spermatheca; and ventral nerve cord. WB:WBGene00004784 seu-2 Acts upstream of or within dorsal/ventral axon guidance. WB:WBGene00004785 seu-3 Acts upstream of or within dorsal/ventral axon guidance. WB:WBGene00004786 sex-1 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in primary sex determination and regulation of gene expression. Located in nucleus. Expressed in gonad; intestine; oocyte; and ventral uterine precursor. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); liver disease (multiple); and lung carcinoma (multiple). Is an ortholog of human NR1D1 (nuclear receptor subfamily 1 group D member 1) and NR1D2 (nuclear receptor subfamily 1 group D member 2). WB:WBGene00004787 sft-1 Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrion. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4K and Leigh disease. Is an ortholog of human SURF1 (SURF1 cytochrome c oxidase assembly factor). WB:WBGene00004788 sft-4 Enables cargo receptor activity. Involved in several processes, including negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of vulval development; and protein exit from endoplasmic reticulum. Located in endoplasmic reticulum exit site and perinuclear region of cytoplasm. Expressed in several structures, including head; hermaphrodite gonad; pharyngeal muscle cell; tail; and vulval precursor cell. Is an ortholog of human SURF4 (surfeit 4). WB:WBGene00004789 sgk-1 Enables phosphatidylinositol-3,4,5-trisphosphate binding activity and protein serine/threonine kinase activity. Involved in several processes, including mesendoderm development; positive regulation of vitellogenesis; and regulation of protein localization to basolateral plasma membrane. Located in cytoplasm and nucleus. Expressed in intestine; neurons; and tail neurons. Human ortholog(s) of this gene implicated in cystadenocarcinoma (multiple); granulosa cell tumor; and hypertension. Is an ortholog of human C8orf44-SGK3 (C8orf44-SGK3 readthrough); SGK2 (serum/glucocorticoid regulated kinase 2); and SGK3 (serum/glucocorticoid regulated kinase family member 3). WB:WBGene00004790 sgn-1 Predicted to be involved in sarcomere organization. Predicted to be located in cytoskeleton and sarcolemma. Predicted to be part of sarcoglycan complex. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2C; autosomal recessive limb-girdle muscular dystrophy type 2F; dilated cardiomyopathy 1L; and type 2 diabetes mellitus. Is an ortholog of human SGCD (sarcoglycan delta); SGCG (sarcoglycan gamma); and SGCZ (sarcoglycan zeta). WB:WBGene00004791 sgs-2 No description available WB:WBGene00004792 shv-1 No description available WB:WBGene00004793 shw-3 Enables voltage-gated potassium channel activity. Involved in potassium ion transport. Located in axolemma; dendrite membrane; and neuronal cell body membrane. Expressed in PLML; PLMR; head neurons; intestine; and tail neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease; electroclinical syndrome (multiple); and glioblastoma. Is an ortholog of human KCNC1 (potassium voltage-gated channel subfamily C member 1); KCNC2 (potassium voltage-gated channel subfamily C member 2); and KCNC4 (potassium voltage-gated channel subfamily C member 4). WB:WBGene00004794 sia-1 No description available WB:WBGene00004795 sid-1 Enables RNA transmembrane transporter activity and double-stranded RNA binding activity. Involved in dsRNA transport and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in plasma membrane. Expressed in several structures, including pharynx. WB:WBGene00004796 sid-2 Involved in RNA transport and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in apical plasma membrane and cytoplasm. Expressed in ciliated neurons; excretory duct; intestine; and in male. WB:WBGene00004798 sip-1 Predicted to enable unfolded protein binding activity. Involved in several processes, including determination of adult lifespan; embryo development; and response to heat. Located in cytosol. Expressed in body wall musculature and gonad. WB:WBGene00004799 sir-2 No description available WB:WBGene00004800 sir-2.1 Enables deacetylase activity. Involved in dauer larval development; determination of adult lifespan; and intrinsic apoptotic signaling pathway in response to DNA damage. Located in chromosome, telomeric region; nucleus; and perinuclear region of cytoplasm. Expressed in several structures, including intestinal cell; neurons; retrovesicular ganglion; tail; and ventral nerve cord. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; non-alcoholic fatty liver disease; and senile cataract. Is an ortholog of human SIRT1 (sirtuin 1). WB:WBGene00004801 sir-2.2 Predicted to enable NAD+ binding activity and NAD-dependent histone deacetylase activity. Involved in innate immune response. Located in mitochondrion. Is an ortholog of human SIRT4 (sirtuin 4). WB:WBGene00004802 sir-2.3 Predicted to enable histone deacetylase activity. Predicted to be involved in chromatin remodeling. Located in mitochondrion. Expressed in body wall musculature; head; pharynx; and somatic gonad. Is an ortholog of human SIRT4 (sirtuin 4). WB:WBGene00004803 sir-2.4 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in P granule assembly and response to heat. Located in P granule; cytoplasmic stress granule; and nuclear envelope. Part of nuclear pore. Expressed in head neurons; spermathecal-uterine valve cell; and tail neurons. Is an ortholog of human SIRT6 (sirtuin 6). WB:WBGene00004804 skn-1 Enables Hsp70 protein binding activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including endoderm development; endoplasmic reticulum unfolded protein response; and positive regulation of macromolecule metabolic process. Located in endoplasmic reticulum; mitochondrion; and nucleus. Expressed in several structures, including germ line; head ganglion; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; liver disease (multiple); obesity; and pulmonary emphysema. Is an ortholog of several human genes including NFE2 (nuclear factor, erythroid 2); NFE2L1 (NFE2 like bZIP transcription factor 1); and NFE2L2 (NFE2 like bZIP transcription factor 2). WB:WBGene00004805 skn-4 No description available WB:WBGene00004806 skp-1 Involved in several processes, including molting cycle; reproductive process; and vulval development. Predicted to be part of spliceosomal complex. Expressed in egg-laying apparatus; hypodermis; pharynx; rectal muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and pancreatic cancer. Is an ortholog of human SNW1 (SNW domain containing 1). WB:WBGene00004807 skr-1 Predicted to enable cullin family protein binding activity. Involved in several processes, including negative regulation of intracellular signal transduction; regulation of cellular component organization; and regulation of protein stability. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including pharynx and spermatheca. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004808 skr-2 Predicted to enable cullin family protein binding activity. Involved in several processes, including establishment of mitotic spindle orientation; regulation of cell cycle; and regulation of protein stability. Part of SCF ubiquitin ligase complex. Expressed in intestine. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004809 skr-3 Predicted to enable cullin family protein binding activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in cytoplasm and nucleus. Expressed in intestine and pharynx. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004810 skr-4 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in intestine. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004811 skr-5 Predicted to enable cullin family protein binding activity. Involved in determination of adult lifespan. Predicted to be located in cytoplasm and nucleus. Expressed in hypodermis; intestinal cell; and vulval muscle. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004812 skr-6 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004813 skr-7 Predicted to enable cullin family protein binding activity. Involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004814 skr-8 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in intestine. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004815 skr-9 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in intestine. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004816 skr-10 Predicted to enable cullin family protein binding activity. Involved in embryo development; larval development; and post-embryonic body morphogenesis. Acts upstream of or within with a positive effect on mitotic cell cycle. Part of SCF ubiquitin ligase complex. Expressed in intestine. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004817 skr-11 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Lithium Chloride; stavudine; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00004818 skr-12 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in ASIL; ASIR; intestine; and pharynx. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004819 skr-13 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004820 skr-14 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004821 skr-15 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004822 skr-16 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004823 skr-17 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004824 F56B3.4 Predicted to be involved in transcription by RNA polymerase II. Is an ortholog of human RPAP1 (RNA polymerase II associated protein 1). WB:WBGene00004825 skr-19 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. WB:WBGene00004826 skr-20 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00004827 skr-21 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. WB:WBGene00004828 sle-1 Acts upstream of or within embryo development and mitotic cell cycle. WB:WBGene00004829 sli-1 Predicted to enable SH3 domain binding activity; receptor tyrosine kinase binding activity; and ubiquitin protein ligase activity. Involved in negative regulation of vulval development. Predicted to be located in membrane raft and plasma membrane. Expressed in several structures, including anal depressor muscle; body wall musculature; distal tip cell; head; and intestine. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung squamous cell carcinoma. Is an ortholog of human CBL (Cbl proto-oncogene); CBLB (Cbl proto-oncogene B); and CBLC (Cbl proto-oncogene C). WB:WBGene00004830 slo-1 Enables calcium-activated potassium channel activity and voltage-gated potassium channel activity. Involved in several processes, including behavioral response to ethanol; pharyngeal pumping; and sarcomere organization. Located in M band; striated muscle dense body; and synapse. Expressed in several structures, including AWC; body wall musculature; non-striated muscle; pharyngeal neurons; and somatic nervous system. Used to study Duchenne muscular dystrophy and alcohol use disorder. Human ortholog(s) of this gene implicated in Alzheimer's disease; idiopathic generalized epilepsy; paroxysmal nonkinesigenic dyskinesia 3; and spermatogenic failure. Is an ortholog of human KCNMA1 (potassium calcium-activated channel subfamily M alpha 1). WB:WBGene00004831 slo-2 Enables calcium-activated potassium channel activity and outward rectifier potassium channel activity. Involved in positive regulation of neurotransmitter secretion and potassium ion transport. Located in axon. Expressed in amphid neurons; body wall musculature; motor neurons; nerve ring; and vulval muscle. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy 5; developmental and epileptic encephalopathy 14; and developmental and epileptic encephalopathy 57. Is an ortholog of human KCNT1 (potassium sodium-activated channel subfamily T member 1) and KCNT2 (potassium sodium-activated channel subfamily T member 2). WB:WBGene00004832 sls-1 No description available WB:WBGene00004833 sls-2.1 Is affected by several genes including daf-12; cep-1; and hpl-2 based on tiling array and RNA-seq studies. WB:WBGene00004834 sls-2.2 Enriched in NSM based on RNA-seq studies. Is affected by daf-12; dcr-1; and etr-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00004835 sls-2.3 Is affected by several genes including daf-12; cep-1; and hpl-2 based on tiling array and RNA-seq studies. WB:WBGene00004836 sls-2.4 Enriched in NSM based on RNA-seq studies. Is affected by several genes including daf-12; cep-1; and car-1 based on tiling array and RNA-seq studies. WB:WBGene00004837 sls-2.5 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00004838 sls-2.6 No description available WB:WBGene00004839 sls-2.7 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00004840 sls-2.8 Is affected by several genes including daf-2; cep-1; and alg-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube and D-glucose based on RNA-seq studies. WB:WBGene00004841 sls-2.9 Is affected by several genes including hpl-2; set-2; and ints-4 based on tiling array and RNA-seq studies. WB:WBGene00004842 sls-2.10 Is affected by clk-1 and set-2 based on microarray and RNA-seq studies. WB:WBGene00004843 sls-2.11 Is affected by several genes including hpl-2; car-1; and set-2 based on tiling array and RNA-seq studies. WB:WBGene00004844 sls-2.12 Is affected by several genes including daf-2; cep-1; and car-1 based on RNA-seq and microarray studies. WB:WBGene00004845 sls-2.13 No description available WB:WBGene00004846 sls-2.14 Is affected by several genes including daf-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00004847 sls-2.15 Enriched in AFD and germ line based on RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and glh-1 based on microarray and RNA-seq studies. WB:WBGene00004848 sls-2.16 Is affected by several genes including daf-2; clk-1; and car-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00004849 sls-2.17 Enriched in germ line based on RNA-seq studies. Is affected by clk-1 and set-2 based on microarray and RNA-seq studies. WB:WBGene00004850 sls-2.18 Is affected by clk-1 and set-2 based on microarray and RNA-seq studies. WB:WBGene00004851 sls-2.19 Is affected by adr-1 based on RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00004854 slt-1 Enables signaling receptor binding activity. Involved in axon guidance; neuron migration; and regulation of neuron projection development. Predicted to be located in extracellular region. Expressed in anal sphincter muscle; anterior hypodermis; body wall musculature; nerve ring neurons; and socket cell. Human ortholog(s) of this gene implicated in atrial fibrillation; myositis (multiple); and proliferative diabetic retinopathy. Is an ortholog of human SLIT1 (slit guidance ligand 1); SLIT2 (slit guidance ligand 2); and SLIT3 (slit guidance ligand 3). WB:WBGene00004855 sma-1 Predicted to enable actin filament binding activity. Involved in several processes, including pharyngeal gland morphogenesis; pharynx development; and regulation of anatomical structure size. Located in apical plasma membrane; cytoplasm; and nucleus. Expressed in several structures, including excretory cell; hermaphrodite gonad; neurons; pharynx; and vulval cell. Is an ortholog of human SPTBN5 (spectrin beta, non-erythrocytic 5). WB:WBGene00004856 sma-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; I-SMAD binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including male anatomical structure morphogenesis; pharynx development; and regulation of anatomical structure morphogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of heteromeric SMAD protein complex. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including Loeys-Dietz syndrome 3; carcinoma (multiple); and reproductive organ cancer (multiple). Is an ortholog of human SMAD9 (SMAD family member 9). WB:WBGene00004857 sma-3 Enables transcription coactivator activity. Involved in several processes, including defense response to other organism; male anatomical structure morphogenesis; and regulation of developmental process. Located in cytoplasm and nucleus. Expressed in several structures, including hypodermis; intestine; pharynx; somatic gonad; and tail. WB:WBGene00004858 sma-4 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; I-SMAD binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; nematode male tail tip morphogenesis; and positive regulation of growth. Predicted to be located in cytoplasm and nucleus. Predicted to be part of heteromeric SMAD protein complex. Expressed in head neurons and pseudocoelom. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); colorectal adenoma; and female reproductive organ cancer (multiple). Is an ortholog of human SMAD4 (SMAD family member 4). WB:WBGene00004859 sma-5 Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including determination of adult lifespan; parturition; and positive regulation of cell size. Predicted to be located in cytoplasm and nucleus. Expressed in excretory cell; hypodermis; intestine; and pharynx. WB:WBGene00004860 sma-6 Enables BMP binding activity. Involved in several processes, including defense response to other organism; nematode male tail tip morphogenesis; and positive regulation of nitrogen compound metabolic process. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in ASI; hypodermis; intestinal cell; pharynx; and tail. Human ortholog(s) of this gene implicated in several diseases, including bone development disease (multiple); carcinoma (multiple); and glaucoma (multiple). Is an ortholog of human BMPR1B (bone morphogenetic protein receptor type 1B). WB:WBGene00004861 sma-8 No description available WB:WBGene00004862 sma-9 Enables transcription coactivator activity and transcription corepressor activity. Involved in several processes, including determination of adult lifespan; nematode male tail tip morphogenesis; and regulation of gene expression. Acts upstream of or within cellular response to heat. Located in nucleus. Expressed in several structures, including excretory cell; intestine; spermatheca; ventral cord neurons; and vulva. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 43. Is an ortholog of human HIVEP1 (HIVEP zinc finger 1); HIVEP2 (HIVEP zinc finger 2); and HIVEP3 (HIVEP zinc finger 3). WB:WBGene00004864 sma-12 Acts upstream of or within transforming growth factor beta receptor signaling pathway. WB:WBGene00004865 sma-13 Acts upstream of or within transforming growth factor beta receptor signaling pathway. WB:WBGene00004866 sma-14 Acts upstream of or within nematode male tail tip morphogenesis and transforming growth factor beta receptor signaling pathway. WB:WBGene00004867 sma-15 No description available WB:WBGene00004868 sma-16 Acts upstream of or within nematode male tail tip morphogenesis. WB:WBGene00004869 sma-17 No description available WB:WBGene00004870 sma-18 No description available WB:WBGene00004871 sma-19 Acts upstream of or within transforming growth factor beta receptor signaling pathway. WB:WBGene00004872 sma-20 Acts upstream of or within dauer larval development and nematode male tail tip morphogenesis. WB:WBGene00004873 smc-3 Predicted to enable cohesin loader activity and double-stranded DNA binding activity. Predicted to be involved in mitotic sister chromatid cohesion. Part of chromatin and cohesin complex. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 3; hepatocellular carcinoma; and intellectual disability. Is an ortholog of human SMC3 (structural maintenance of chromosomes 3). WB:WBGene00004874 smc-4 Predicted to enable ATP binding activity and ATP hydrolysis activity. Involved in mitotic sister chromatid segregation and positive regulation of nematode male tail tip morphogenesis. Located in chromosome, centromeric region and condensed chromosome. Expressed in head; linker cell; and tail. Is an ortholog of human SMC4 (structural maintenance of chromosomes 4). WB:WBGene00004875 smd-1 Enables adenosylmethionine decarboxylase activity. Involved in spermidine biosynthetic process and spermine biosynthetic process. Predicted to be located in cytosol. Expressed in intestine and neurons. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and prostate cancer. Is an ortholog of human AMD1 (adenosylmethionine decarboxylase 1). WB:WBGene00004876 smf-1 Predicted to enable cadmium ion transmembrane transporter activity; iron ion transmembrane transporter activity; and manganese ion transmembrane transporter activity. Involved in monoatomic cation homeostasis; negative regulation of cellular response to manganese ion; and response to manganese ion. Located in apical plasma membrane. Expressed in several structures, including excretory cell; hermaphrodite gonad; intestine; nerve ring; and neurons. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); leishmaniasis (multiple); and neurodegenerative disease (multiple). Is an ortholog of human SLC11A1 (solute carrier family 11 member 1) and SLC11A2 (solute carrier family 11 member 2). WB:WBGene00004877 smf-2 Predicted to enable cadmium ion transmembrane transporter activity; iron ion transmembrane transporter activity; and manganese ion transmembrane transporter activity. Involved in intracellular iron ion homeostasis; manganese ion homeostasis; and response to manganese ion. Located in apical plasma membrane. Expressed in dopaminergic neurons; gonadal sheath cell; marginal cell; and pharyngeal-intestinal valve. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); leishmaniasis (multiple); and neurodegenerative disease (multiple). Is an ortholog of human SLC11A1 (solute carrier family 11 member 1) and SLC11A2 (solute carrier family 11 member 2). WB:WBGene00004878 smf-3 Predicted to enable cadmium ion transmembrane transporter activity; iron ion transmembrane transporter activity; and manganese ion transmembrane transporter activity. Involved in several processes, including defense response to Gram-negative bacterium; monoatomic cation homeostasis; and response to manganese ion. Located in apical plasma membrane and organelle membrane. Expressed in several structures, including excretory cell; hypodermal cell; intestinal cell; neurons; and vulva. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); leishmaniasis (multiple); and neurodegenerative disease (multiple). Is an ortholog of human SLC11A1 (solute carrier family 11 member 1) and SLC11A2 (solute carrier family 11 member 2). WB:WBGene00004879 smg-1 Predicted to enable protein serine/threonine kinase activity. Involved in male genitalia development; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and obsolete hermaphrodite genitalia development. Predicted to be located in nucleus. Predicted to be part of TORC1 complex and TORC2 complex. Is an ortholog of human SMG1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase). WB:WBGene00004880 smg-2 Enables protein phosphatase 2A binding activity. Involved in embryonic genitalia morphogenesis; ncRNA metabolic process; and negative regulation of gene expression. Located in cytoplasm and nucleus. Expressed in intestinal cell and muscle cell. Is an ortholog of human UPF1 (UPF1 RNA helicase and ATPase). WB:WBGene00004881 smg-3 Enables enzyme binding activity. Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be located in cytoplasm. Predicted to be part of exon-exon junction complex and polysome. Is an ortholog of human UPF2 (UPF2 regulator of nonsense mediated mRNA decay). WB:WBGene00004882 smg-4 Predicted to enable mRNA binding activity. Involved in male genitalia development; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and obsolete hermaphrodite genitalia development. Located in nucleus and perinuclear region of cytoplasm. Expressed in intestinal cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 14. Is an ortholog of human UPF3A (UPF3A regulator of nonsense mediated mRNA decay) and UPF3B (UPF3B regulator of nonsense mediated mRNA decay). WB:WBGene00004883 smg-5 Enables DEAD/H-box RNA helicase binding activity and protein phosphatase 2A binding activity. Involved in embryonic genitalia morphogenesis; ncRNA metabolic process; and negative regulation of gene expression. Located in cytoplasm and nucleus. WB:WBGene00004884 smg-6 Predicted to enable telomerase RNA binding activity and telomeric DNA binding activity. Involved in embryonic genitalia morphogenesis; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be located in cytoplasm. Predicted to be part of telomerase holoenzyme complex. Is an ortholog of human SMG6 (SMG6 nonsense mediated mRNA decay factor). WB:WBGene00004885 smg-7 Predicted to enable telomerase RNA binding activity and telomeric DNA binding activity. Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Located in cytoplasm and nucleus. Is an ortholog of human SMG7 (SMG7 nonsense mediated mRNA decay factor). WB:WBGene00004886 smi-1 Involved in embryo development. Located in cytoplasm. Expressed in body wall musculature; intestine; and ventral cord neurons. Used to study spinal muscular atrophy. Is an ortholog of human GEMIN2 (gem nuclear organelle associated protein 2). WB:WBGene00004887 smn-1 Enables protein self-association. Involved in several processes, including determination of adult lifespan; pharyngeal pumping; and vulval development. Located in nucleus. Expressed in several structures, including body wall musculature; excretory cell; hypodermis; intestine; and vulval muscle. Used to study spinal muscular atrophy. Human ortholog(s) of this gene implicated in spinal muscular atrophy (multiple). Is an ortholog of human SMN1 (survival of motor neuron 1, telomeric) and SMN2 (survival of motor neuron 2, centromeric). WB:WBGene00004888 smo-1 Enables identical protein binding activity. Involved in several processes, including chromosome organization; multicellular organismal locomotion; and muscle cell cellular homeostasis. Predicted to be located in PML body. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; hermaphrodite somatic gonadal cell; and ventral nerve cord. Human ortholog(s) of this gene implicated in orofacial cleft 10. Is an ortholog of human SUMO1P1 (SUMO1 pseudogene 1). WB:WBGene00004889 smp-1 Enables semaphorin receptor binding activity. Involved in nematode male tail mating organ morphogenesis. Predicted to be located in membrane. Expressed in several structures, including hermaphrodite distal tip cell; non-striated muscle; ray; somatic nervous system; and vulval cell. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 16 with or without anosmia; progressive myoclonus epilepsy; and rheumatoid arthritis. Is an ortholog of several human genes including SEMA3B (semaphorin 3B); SEMA3C (semaphorin 3C); and SEMA6C (semaphorin 6C). WB:WBGene00004890 smp-2 Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Involved in nematode male tail mating organ morphogenesis. Predicted to be located in membrane. Expressed in several structures, including hook; inner labial neurons; pharyngeal cell; ray; and vulval cell. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy. Is an ortholog of several human genes including SEMA6A (semaphorin 6A); SEMA6B (semaphorin 6B); and SEMA6C (semaphorin 6C). WB:WBGene00004891 smr-1 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Is an ortholog of human SMNDC1 (survival motor neuron domain containing 1). WB:WBGene00004892 sms-1 Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in Golgi membrane. Expressed in head muscle; pharyngeal cell; rectal muscle; spermatheca; and vulval muscle. Human ortholog(s) of this gene implicated in calvarial doughnut lesions with bone fragility. Is an ortholog of human SGMS2 (sphingomyelin synthase 2). WB:WBGene00004893 sms-2 Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in membrane. WB:WBGene00004894 sms-3 Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in membrane. WB:WBGene00004895 smu-1 Enables protein homodimerization activity. Involved in several processes, including mechanosensory behavior; nematode larval development; and regulation of alternative mRNA splicing, via spliceosome. Located in nucleus. Expressed in several structures, including germ line. Is an ortholog of human SMU1 (SMU1 DNA replication regulator and spliceosomal factor). WB:WBGene00004896 smu-2 Involved in several processes, including mechanosensory behavior; nematode larval development; and regulation of alternative mRNA splicing, via spliceosome. Located in nucleolus. Expressed widely. Is an ortholog of human IK (IK cytokine). WB:WBGene00004897 snb-1 Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in several processes, including chemical synaptic transmission; defecation; and regulation of hindgut contraction. Located in several cellular components, including axon; presynaptic active zone; and secretory vesicle. Expressed in several structures, including AIY; CAN; excretory gland cell; somatic nervous system; and uv1. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and spastic ataxia 1. Is an ortholog of human VAMP2 (vesicle associated membrane protein 2). WB:WBGene00004898 snb-2 Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in vesicle fusion. Predicted to be located in plasma membrane. Predicted to be part of SNARE complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and spastic ataxia 1. Is an ortholog of human VAMP1 (vesicle associated membrane protein 1) and VAMP3 (vesicle associated membrane protein 3). WB:WBGene00004899 snb-5 Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in vesicle fusion. Predicted to be located in plasma membrane. Predicted to be part of SNARE complex. Is an ortholog of human VAMP7 (vesicle associated membrane protein 7). WB:WBGene00004900 snf-1 Predicted to enable symporter activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00004901 snf-2 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC6A7 (solute carrier family 6 member 7). WB:WBGene00004902 snf-3 Enables amino-acid betaine transmembrane transporter activity. Involved in amino-acid betaine transport. Predicted to be located in neuron projection. Expressed in excretory canal; neurons; tail hypodermis; and vulval cell. WB:WBGene00004903 snf-4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including hydrogen sulfide; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00004904 snf-5 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in plasma membrane. Expressed in amphid neurons; intestinal cell; pharyngeal neurons; and rectal gland cell. Is an ortholog of human SLC6A7 (solute carrier family 6 member 7). WB:WBGene00004905 snf-6 Enables PDZ domain binding activity and acetylcholine transmembrane transporter activity. Involved in acetylcholine transport; choline transport; and positive regulation of locomotion. Predicted to be located in postsynaptic membrane. Expressed in body wall musculature; enteric muscle; neurons; and vulval muscle. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in hyperekplexia 3 and obesity. Is an ortholog of human SLC6A14 (solute carrier family 6 member 14) and SLC6A5 (solute carrier family 6 member 5). WB:WBGene00004906 snf-7 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC6A7 (solute carrier family 6 member 7). WB:WBGene00004907 snf-8 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-12; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including Tunicamycin; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00004908 snf-9 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC6A7 (solute carrier family 6 member 7). WB:WBGene00004909 snf-10 Predicted to enable L-amino acid transmembrane transporter activity. Involved in positive regulation of amoeboid sperm motility. Located in cell body membrane. Expressed in germ line; secondary spermatocyte; sperm; spermatid; and spermatocyte. Is an ortholog of human SLC6A7 (solute carrier family 6 member 7). WB:WBGene00004910 snf-11 Enables gamma-aminobutyric acid:sodium:chloride symporter activity. Involved in gamma-aminobutyric acid transport. Located in neuron projection and neuronal cell body. Expressed in several structures, including GLR; enteric muscle; head mesodermal cell; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in myoclonic-atonic epilepsy and temporal lobe epilepsy. Is an ortholog of human SLC6A1 (solute carrier family 6 member 1). WB:WBGene00004911 snf-12 Enables STAT family protein binding activity. Involved in positive regulation of antifungal peptide production. Located in apical part of cell and endocytic vesicle. Expressed in excretory cell; hypodermis; socket cell; and vulva. WB:WBGene00004912 sng-1 Predicted to be involved in regulation of exocytosis and synaptic vesicle transport. Located in synaptic vesicle. Expressed in muscle cell and nervous system. Is an ortholog of human SYNGR1 (synaptogyrin 1); SYNGR2 (synaptogyrin 2); and SYNGR4 (synaptogyrin 4). WB:WBGene00004913 snn-1 Predicted to enable ATP binding activity. Involved in neuromuscular synaptic transmission. Located in presynaptic periactive zone. Expressed in epithelial cell and nervous system. Human ortholog(s) of this gene implicated in several diseases, including X-linked epilepsy with variable learning disabilities and behavior disorders; major depressive disorder; and non-syndromic X-linked intellectual disability 50. Is an ortholog of human SYN3 (synapsin III). WB:WBGene00004914 snr-1 Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Located in P granule. Expressed in germ line; gonad; head; and tail. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Is an ortholog of human SNRPD3 (small nuclear ribonucleoprotein D3 polypeptide). WB:WBGene00004915 snr-2 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytoplasm. Predicted to be part of spliceosomal complex and spliceosomal snRNP complex. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including Prader-Willi syndrome; cerebrocostomandibular syndrome; and mixed connective tissue disease. Is an ortholog of human SNRPN (small nuclear ribonucleoprotein polypeptide N) and SNURF (SNRPN upstream open reading frame). WB:WBGene00004916 snr-3 Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Located in P granule. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including nasopharynx carcinoma; nephritis; and systemic lupus erythematosus. Is an ortholog of human SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide). WB:WBGene00004917 snr-4 Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in cytosol and nucleus. Predicted to be part of pICln-Sm protein complex; spliceosomal complex; and spliceosomal snRNP complex. Expressed in gonad. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Is an ortholog of human SNRPD2 (small nuclear ribonucleoprotein D2 polypeptide). WB:WBGene00004918 snr-5 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol and nucleus. Predicted to be part of U1 snRNP; catalytic step 2 spliceosome; and pICln-Sm protein complex. Expressed in several structures, including enteric muscle; excretory cell; hypodermis; nervous system; and reproductive system. Human ortholog(s) of this gene implicated in nasopharynx carcinoma. Is an ortholog of human SNRPF (small nuclear ribonucleoprotein polypeptide F). WB:WBGene00004919 snr-6 Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Located in P granule. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hypotrichosis (multiple); and lupus nephritis. Is an ortholog of human SNRPE (small nuclear ribonucleoprotein polypeptide E). WB:WBGene00004920 snr-7 Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in P granule. Expressed in gonad. Human ortholog(s) of this gene implicated in nasopharynx carcinoma. Is an ortholog of human SNRPG (small nuclear ribonucleoprotein polypeptide G). WB:WBGene00004921 snt-1 Enables calcium ion sensor activity and calcium-dependent phospholipid binding activity. Involved in several processes, including defecation; regulation of pharyngeal pumping; and synaptic vesicle endocytosis. Located in synaptic vesicle. Expressed in several structures, including excretory gland cell; gonad; nervous system; pharyngeal gland cell; and rectal gland cell. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 7. Is an ortholog of human SYT1 (synaptotagmin 1). WB:WBGene00004922 snt-2 Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Predicted to be involved in cellular response to calcium ion; regulation of secretion by cell; and synaptic vesicle cycle. Located in dense core granule. Expressed in head neurons; intestine; and tail neurons. WB:WBGene00004923 snt-3 Enables calcium ion sensor activity and calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion; regulation of secretion by cell; and synaptic vesicle cycle. Predicted to be located in axon; plasma membrane; and secretory vesicle. Expressed in body wall musculature; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 7. Is an ortholog of human SYT1 (synaptotagmin 1) and SYT2 (synaptotagmin 2). WB:WBGene00004924 snt-4 Predicted to enable several functions, including SNARE binding activity; calcium ion binding activity; and phospholipid binding activity. Predicted to be involved in cellular response to calcium ion; regulation of secretion by cell; and vesicle-mediated transport. Predicted to be located in several cellular components, including axon; exocytic vesicle; and synapse. Expressed in intestine. Is an ortholog of human SYT4 (synaptotagmin 4). WB:WBGene00004925 snt-5 Predicted to enable several functions, including SNARE binding activity; calcium ion binding activity; and phospholipid binding activity. Predicted to be involved in cellular response to calcium ion; regulation of secretion by cell; and vesicle-mediated transport. Predicted to be located in several cellular components, including axon; exocytic vesicle; and synapse. Is an ortholog of several human genes including SYT3 (synaptotagmin 3); SYT6 (synaptotagmin 6); and SYT9 (synaptotagmin 9). WB:WBGene00004926 snt-6 Predicted to enable several functions, including SNARE binding activity; calcium ion binding activity; and phospholipid binding activity. Predicted to be involved in cellular response to calcium ion; regulation of secretion by cell; and vesicle-mediated transport. Predicted to be located in several cellular components, including axon; exocytic vesicle; and synapse. Is an ortholog of human SYT7 (synaptotagmin 7). WB:WBGene00004927 snx-1 Enables phosphatidylinositol-3,4,5-trisphosphate binding activity and protein self-association. Involved in several processes, including mechanosensory behavior; protein localization to postsynaptic membrane; and vesicle-mediated transport. Located in early endosome and early phagosome. Expressed in body wall musculature; gonadal sheath cell; head; hypodermis; and tail. Is an ortholog of human SNX1 (sorting nexin 1) and SNX2 (sorting nexin 2). WB:WBGene00004928 soc-1 Involved in dauer larval development. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 26 and chronic myeloid leukemia. Is an ortholog of several human genes including GAB1 (GRB2 associated binding protein 1); GAB2 (GRB2 associated binding protein 2); and GAB4 (GRB2 associated binding protein family member 4). WB:WBGene00004929 soc-2 Enables small GTPase binding activity. Involved in several processes, including fibroblast growth factor receptor signaling pathway; positive regulation of Ras protein signal transduction; and vulval development. Expressed in tail. Human ortholog(s) of this gene implicated in Noonan syndrome-like disorder with loose anagen hair 1 and atopic dermatitis. Is an ortholog of human SHOC2 (SHOC2 leucine rich repeat scaffold protein). WB:WBGene00004930 sod-1 Enables copper ion binding activity; protein homodimerization activity; and superoxide dismutase activity. Involved in regulation of brood size; regulation of vulval development; and removal of superoxide radicals. Located in cytosol and mitochondrion. Expressed in several structures, including intestinal cell; somatic gonad; and somatic nervous system. Used to study amyotrophic lateral sclerosis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); eye disease (multiple); and glucose metabolism disease (multiple). Is an ortholog of human SOD1 (superoxide dismutase 1). WB:WBGene00004931 sod-2 Enables protein homodimerization activity and superoxide dismutase activity. Involved in removal of superoxide radicals. Located in mitochondrial respirasome. Expressed in head and tail. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and hematologic cancer (multiple). Is an ortholog of human SOD2 (superoxide dismutase 2). WB:WBGene00004932 sod-3 Enables protein homodimerization activity and superoxide dismutase activity. Involved in removal of superoxide radicals. Located in mitochondrial respirasome. Expressed in several structures, including head; intestine; pharynx; tail; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and hematologic cancer (multiple). Is an ortholog of human SOD2 (superoxide dismutase 2). WB:WBGene00004933 sod-4 Enables superoxide dismutase activity. Involved in superoxide metabolic process. Located in extracellular space and membrane. Expressed in somatic gonad. WB:WBGene00004935 sog-2 Acts upstream of or within embryo development and germ cell development. WB:WBGene00004936 sog-3 Acts upstream of or within embryo development and germ cell development. WB:WBGene00004937 sog-4 Acts upstream of or within embryo development and germ cell development. WB:WBGene00004938 sog-5 Acts upstream of or within embryo development and germ cell development. WB:WBGene00004939 sog-6 Acts upstream of or within embryo development and germ cell development. WB:WBGene00004940 sog-7 No description available WB:WBGene00004941 sog-8 No description available WB:WBGene00004942 sog-9 No description available WB:WBGene00004943 sog-10 Acts upstream of or within embryo development; germ cell development; and masculinization of hermaphroditic germ-line. WB:WBGene00004944 sol-1 Enables channel regulator activity. Involved in several processes, including hyperosmotic response; positive regulation of glutamatergic synaptic transmission; and thigmotaxis. Located in neuron projection membrane and synapse. Part of ionotropic glutamate receptor complex. WB:WBGene00004945 sop-2 Enables RNA binding activity; protein homodimerization activity; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of cytoplasmic mRNA processing body assembly; neuron differentiation; and regulation of gene expression. Located in nuclear speck. Expressed widely. WB:WBGene00004946 sop-3 Predicted to be located in nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and neurons. WB:WBGene00004947 sos-1 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; female gamete generation; and positive regulation of vulval development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 4; Noonan syndrome 9; and reproductive organ cancer (multiple). Is an ortholog of human SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1). WB:WBGene00004949 sox-2 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in neuron fate specification. Predicted to be located in nucleus. Expressed in several structures, including AWC-ON; head neurons; hypodermis; neuroblasts; and rectal epithelial cell. Human ortholog(s) of this gene implicated in several diseases, including X-linked panhypopituitarism; carcinoma (multiple); and syndromic microphthalmia 3. Is an ortholog of human SOX2 (SRY-box transcription factor 2). WB:WBGene00004950 sox-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in neuron differentiation. Predicted to be located in nucleus. Expressed in head neurons and rectal epithelial cell. Is an ortholog of human SOX14 (SRY-box transcription factor 14) and SOX21 (SRY-box transcription factor 21). WB:WBGene00004951 spc-1 Predicted to enable actin filament binding activity. Involved in several processes, including embryonic body morphogenesis; nematode larval development; and regulation of growth. Predicted to be located in several cellular components, including cell junction; cortical actin cytoskeleton; and plasma membrane. Expressed in several structures, including body wall musculature; hermaphrodite gonad; intestine; pharynx; and vulval cell. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 5 and hereditary spherocytosis type 3. Is an ortholog of human SPTAN1 (spectrin alpha, non-erythrocytic 1). WB:WBGene00004952 spd-1 Enables microtubule binding activity. Involved in several processes, including ciliary body morphogenesis; gonad development; and microtubule bundle formation involved in mitotic spindle midzone assembly. Located in microtubule; mitotic spindle midzone; and nucleus. Is an ortholog of human PRC1 (protein regulator of cytokinesis 1). WB:WBGene00004953 spd-2 Enables protein kinase binding activity. Involved in several processes, including centriole replication; embryo development; and vulval development. Located in centriole; cytoplasm; and pericentriolar material. Expressed in intestinal cell. WB:WBGene00004954 spd-3 Involved in several processes, including homologous chromosome segregation; microtubule cytoskeleton organization; and vulval development. Located in mitochondrion. WB:WBGene00004955 spd-5 Enables identical protein binding activity. Involved in centrosome cycle; positive regulation of mitotic cell cycle, embryonic; and protein localization to organelle. Located in centrosome and cytoplasm. WB:WBGene00004956 spe-1 No description available WB:WBGene00004957 spe-3 No description available WB:WBGene00004958 spe-4 Predicted to enable endopeptidase activity. Involved in cellular component organization; protein localization; and spermatid development. Located in intracellular membrane-bounded organelle. Expressed in male. WB:WBGene00004959 spe-5 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in intracellular pH reduction; positive regulation of programmed cell death; and spermatocyte division. Located in cytoplasm. Expressed in sperm and spermatocyte. Human ortholog(s) of this gene implicated in autosomal dominant congenital deafness with onychodystrophy and renal tubular acidosis. Is an ortholog of human ATP6V1B1 (ATPase H+ transporting V1 subunit B1) and ATP6V1B2 (ATPase H+ transporting V1 subunit B2). WB:WBGene00004960 spe-6 Predicted to enable protein serine/threonine kinase activity. Involved in male meiosis chromosome separation; regulation of protein localization; and spermatid differentiation. Predicted to be located in nucleus. Expressed in sperm. WB:WBGene00004961 spe-7 Acts upstream of or within spermatogenesis. WB:WBGene00004962 spe-8 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Involved in spermatid development. Located in plasma membrane. Expressed in sperm and spermatocyte. WB:WBGene00004963 spe-9 Predicted to enable signaling receptor binding activity. Involved in single fertilization. Located in several cellular components, including cell surface; cytoplasm; and pseudopodium. Expressed in sperm and spermatid. Human ortholog(s) of this gene implicated in several diseases, including Adams-Oliver syndrome; limb ischemia; and temporal arteritis. Is an ortholog of human DLL1 (delta like canonical Notch ligand 1) and DLL4 (delta like canonical Notch ligand 4). WB:WBGene00004964 spe-10 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including amoeboid sperm motility; cellular component organization; and spermatid development. Located in membrane-bounded organelle. Expressed in spermatid. WB:WBGene00004965 spe-11 Involved in eggshell formation and prevention of polyspermy. Located in nucleus. WB:WBGene00004966 spe-12 Involved in spermatid development. Located in plasma membrane. Expressed in spermatid and in male. WB:WBGene00004967 spe-13 Acts upstream of or within single fertilization. WB:WBGene00004968 spe-14 No description available WB:WBGene00004969 spe-15 Predicted to enable actin filament binding activity and microfilament motor activity. Involved in organelle localization and spermatid development. Predicted to be located in actin cytoskeleton and endocytic vesicle. Predicted to be part of myosin complex. Expressed in primary spermatocyte. Human ortholog(s) of this gene implicated in auditory system disease (multiple) and reproductive organ cancer (multiple). Is an ortholog of human MYO6 (myosin VI). WB:WBGene00004970 spe-16 No description available WB:WBGene00004971 spe-17 Involved in spermatid development. WB:WBGene00004972 spe-26 Predicted to enable actin binding activity. Predicted to be located in cytoplasm and cytoskeleton. Expressed in spermatocyte and in male. Human ortholog(s) of this gene implicated in spermatogenic failure 11. Is an ortholog of human KLHL10 (kelch like family member 10). WB:WBGene00004973 spe-27 Involved in spermatid development. Expressed in sperm; spermatocyte; and in male. WB:WBGene00004974 spe-29 Involved in spermatid development. Predicted to be located in membrane. WB:WBGene00004975 spe-39 Involved in germ cell development; vacuolar protein processing; and vacuolar transport. Located in cytoplasm. Expressed in male-specific anatomical entity and in male. Human ortholog(s) of this gene implicated in arthrogryposis, renal dysfunction, and cholestasis 2. Is an ortholog of human VIPAS39 (VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog). WB:WBGene00004976 spe-41 Enables store-operated calcium channel activity. Involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization. Located in cytoplasmic vesicle and pseudopodium membrane. Expressed in sperm and spermatid. WB:WBGene00004977 spf-1 No description available WB:WBGene00004978 spg-7 Predicted to enable metalloendopeptidase activity. Involved in several processes, including mitochondrial protein processing; positive regulation of nematode male tail tip morphogenesis; and regulation of gene expression. Predicted to be located in mitochondrion. Predicted to be part of m-AAA complex. Expressed in germ line. Human ortholog(s) of this gene implicated in optic atrophy 12; spastic ataxia 5; and spinocerebellar ataxia type 28. Is an ortholog of human AFG3L2 (AFG3 like matrix AAA peptidase subunit 2). WB:WBGene00004979 sph-1 Located in cytoplasmic vesicle. Expressed in anal sphincter muscle and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in Alzheimer's disease and non-syndromic X-linked intellectual disability 96. Is an ortholog of human SYNPR (synaptoporin) and SYPL1 (synaptophysin like 1). WB:WBGene00004980 spk-1 Enables protein serine/threonine kinase activity. Involved in embryo development. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including gonad and tail. Is an ortholog of human SRPK1 (SRSF protein kinase 1); SRPK2 (SRSF protein kinase 2); and SRPK3 (SRSF protein kinase 3). WB:WBGene00004981 spl-1 Predicted to enable sphinganine-1-phosphate aldolase activity. Predicted to be involved in sphingolipid catabolic process. Predicted to be located in endoplasmic reticulum. Expressed in head and intestine. Human ortholog(s) of this gene implicated in nephrotic syndrome type 14. Is an ortholog of human SGPL1 (sphingosine-1-phosphate lyase 1). WB:WBGene00004984 spn-4 Predicted to enable mRNA binding activity. Predicted to be involved in nervous system development and regulation of alternative mRNA splicing, via spliceosome. Located in P granule. Expressed in several structures, including Psub4; Z2; Z3; germ line; and oocyte. WB:WBGene00004985 spo-11 Predicted to enable DNA binding activity. Involved in meiotic DNA double-strand break processing. Predicted to be located in nuclear chromosome. Is an ortholog of human SPO11 (SPO11 initiator of meiotic double strand breaks). WB:WBGene00004986 spp-1 Enables pore-forming activity. Involved in defense response to other organism and pore formation in membrane of another organism. Part of pore complex. WB:WBGene00004987 spp-2 Involved in defense response to Gram-positive bacterium. WB:WBGene00004988 spp-3 Enables identical protein binding activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Located in protein-containing complex. Expressed in SDQR. WB:WBGene00004989 spp-4 Enriched in hypodermis; intestine; male-specific anatomical entity; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including Heme; methylmercuric chloride; and bisphenol S based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Saposin-like type B, region 2; Saposin-like; Saposin B type domain; Saposin B type, region 2; and Phosphorylation site. WB:WBGene00004990 spp-5 Enables channel activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. WB:WBGene00004991 spp-6 Enriched in ALM; PLM; body wall muscle cell; and intestine based on tiling array; microarray; and RNA-seq studies. Is affected by several genes including skn-1; daf-12; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Saposin-like type B, region 2; Saposin-like; Saposin B type domain; and Saposin B type, region 2. WB:WBGene00004992 spp-7 Expressed in head neurons; intestine; and pm7. Is predicted to encode a protein with the following domains: Saposin-like type B, region 2; Saposin-like; Saposin B type domain; and Saposin B type, region 2. WB:WBGene00004993 spp-8 Enriched in OLL; PVD; hermaphrodite distal tip cell; intestine; and male distal tip cell based on SAGE; microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including 1-methylnicotinamide; mianserin; and D-glucose based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in atypical Gaucher's disease due to saposin c deficiency; combined saposin deficiency; and late onset Parkinson's disease. Human PSAP enables several functions, including ganglioside binding activity; protein homodimerization activity; and scaffold protein binding activity. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. Is an ortholog of human PSAP (prosaposin). WB:WBGene00004994 spp-9 Expressed in intestine and odorsensory neurons. Is predicted to encode a protein with the following domains: Saposin-like type B, region 2; Saposin-like; Saposin B type domain; and Saposin B type, region 2. WB:WBGene00004995 spp-10 Predicted to be involved in sphingolipid metabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including cystic fibrosis; lung disease (multiple); and sphingolipidosis (multiple). Is an ortholog of human PSAP (prosaposin) and PSAPL1 (prosaposin like 1). WB:WBGene00004996 spp-11 Enriched in ABprpapppa; anterior arcade cell; and dopaminergic neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pmk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including glycine; Chlorpyrifos; and single-walled carbon nanotube based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 3 and Charcot-Marie-Tooth disease type 4F. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. Is an ortholog of human PRX (periaxin). WB:WBGene00004997 spp-12 Enables pore-forming activity. Involved in defense response to Gram-positive bacterium and pore formation in membrane of another organism. Part of pore complex. Expressed in I4 neuron; I6 neuron; M4 neuron; NSML; and NSMR. WB:WBGene00004998 spp-13 Enriched in several structures, including head mesodermal cell; hypodermis; interfacial epithelial cell; intestine; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including Ethanol; methylmercury hydroxide; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Saposin-like type B, region 2; Saposin-like; Saposin B type domain; and Saposin B type, region 2. WB:WBGene00004999 spp-14 Expressed in male. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. WB:WBGene00005000 spp-15 Enriched in several structures, including body wall muscle cell; coelomocyte; distal tip cell; enteric muscle; and head mesodermal cell based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Saposin-like type B, region 2; Saposin-like; Saposin B type domain; and Saposin B type, region 2. WB:WBGene00005001 spp-16 Enriched in ALA; head mesodermal cell; intestine; and pm8 based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and mianserin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. WB:WBGene00005002 spp-17 Enriched in DA neuron; VA neuron; intestine; and pharyngeal muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by twenty-five chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. WB:WBGene00005003 spp-18 Involved in innate immune response. WB:WBGene00005004 spp-19 Predicted to be located in membrane. WB:WBGene00005005 spp-20 Enriched in dopaminergic neurons and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; age-1; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including diallyl trisulfide; Tunicamycin; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. WB:WBGene00005006 spr-1 Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of histone deacetylase complex and transcription regulator complex. Used to study Alzheimer's disease. Is an ortholog of human RCOR1 (REST corepressor 1); RCOR2 (REST corepressor 2); and RCOR3 (REST corepressor 3). WB:WBGene00005007 spr-2 Predicted to enable chromatin binding activity and histone binding activity. Involved in regulation of egg-laying behavior. Located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in several diseases, including hepatocellular carcinoma; seminoma; and sudden infant death syndrome. Is an ortholog of human SET (SET nuclear proto-oncogene) and SETSIP (SET like protein). WB:WBGene00005008 spr-3 Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in regulation of gene expression. Predicted to be located in nucleus. Used to study Alzheimer's disease. WB:WBGene00005009 spr-4 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in neurons. Used to study Alzheimer's disease and epilepsy. WB:WBGene00005010 spr-5 Enables FAD-dependent H3K4me/H3K4me3 demethylase activity. Involved in epigenetic regulation of gene expression. Located in cytoplasm and nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including alopecia areata; diabetic retinopathy; and hepatocellular carcinoma. Is an ortholog of human KDM1A (lysine demethylase 1A). WB:WBGene00005011 F26F4.8 Enriched in several structures, including ABalaaaala; cephalic sheath cell; ciliated neurons; germ line; and male distal tip cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type and Zinc finger C2H2 superfamily. WB:WBGene00005012 F26F4.2 Enriched in RIC; germ line; intestine; sperm; and in male based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray; RNA-seq; and proteomic studies. WB:WBGene00005013 jmjd-1.1 Predicted to enable histone demethylase activity and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in melanoma; prostate cancer; and syndromic X-linked intellectual disability Siderius type. Is an ortholog of human KDM7A (lysine demethylase 7A). WB:WBGene00005014 spt-4 Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in chromatin organization and regulation of transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of DSIF complex. Is an ortholog of human SUPT4H1 (SPT4 homolog, DSIF elongation factor subunit). WB:WBGene00005015 spt-5 Predicted to enable mRNA binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Part of euchromatin. Expressed in several structures, including head and tail. Is an ortholog of human SUPT5H (SPT5 homolog, DSIF elongation factor subunit). WB:WBGene00005016 sqt-1 A structural constituent of collagen and cuticulin-based cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be part of collagen trimer. WB:WBGene00005017 sqt-2 Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00005018 sqt-3 Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in hypodermis. WB:WBGene00005019 sqv-1 Predicted to enable NAD+ binding activity and UDP-glucuronate decarboxylase activity. Involved in several processes, including egg-laying behavior; pharynx development; and vulval development. Located in cytoplasm. Expressed in coelomocyte; oocyte; uterus; and vulva. Is an ortholog of human UXS1 (UDP-glucuronate decarboxylase 1). WB:WBGene00005020 sqv-2 Enables galactosylxylosylprotein 3-beta-galactosyltransferase activity. Involved in several processes, including egg-laying behavior; glycosaminoglycan biosynthetic process; and vulval development. Located in Golgi apparatus. Expressed in intestine. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome spondylodysplastic type 2 and spondyloepimetaphyseal dysplasia with joint laxity type 1. Is an ortholog of human B3GALT6 (beta-1,3-galactosyltransferase 6). WB:WBGene00005021 sqv-3 Enables galactosyltransferase activity. Involved in several processes, including egg-laying behavior; proteoglycan biosynthetic process; and vulval development. Located in membrane. Used to study Ehlers-Danlos syndrome. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome spondylodysplastic type 1. Is an ortholog of human B4GALT7 (beta-1,4-galactosyltransferase 7). WB:WBGene00005022 sqv-4 Enables UDP-glucose 6-dehydrogenase activity and identical protein binding activity. Involved in several processes, including egg-laying behavior; glycosaminoglycan biosynthetic process; and vulval development. Located in cytoplasm. Expressed in several structures, including germ line; hermaphrodite gonad; hypodermis; oocyte; and vulva. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 84. Is an ortholog of human UGDH (UDP-glucose 6-dehydrogenase). WB:WBGene00005023 sqv-5 Enables enzyme binding activity. Involved in several processes, including egg-laying behavior; positive regulation of vulval development; and vulval development. Located in cytoplasm. Expressed in oocyte; uterus; and vulva. Human ortholog(s) of this gene implicated in temtamy preaxial brachydactyly syndrome. Is an ortholog of human CHSY1 (chondroitin sulfate synthase 1) and CHSY3 (chondroitin sulfate synthase 3). WB:WBGene00005024 sqv-6 Enables protein xylosyltransferase activity. Involved in several processes, including UDP-D-xylose metabolic process; egg-laying behavior; and glycosaminoglycan biosynthetic process. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Desbuquois dysplasia; pseudoxanthoma elasticum; and type 1 diabetes mellitus. Is an ortholog of human XYLT1 (xylosyltransferase 1). WB:WBGene00005025 sqv-7 Enables UDP-N-acetylgalactosamine transmembrane transporter activity; UDP-galactose transmembrane transporter activity; and UDP-glucuronic acid transmembrane transporter activity. Involved in several processes, including egg-laying behavior; proteoglycan biosynthetic process; and pyrimidine nucleotide-sugar transmembrane transport. Located in cytoplasm. Expressed in hermaphrodite distal tip cell; oocyte; seam cell; and vulval cell. Human ortholog(s) of this gene implicated in schneckenbecken dysplasia. Is an ortholog of human SLC35D1 (solute carrier family 35 member D1). WB:WBGene00005026 sqv-8 Enables glucuronosyltransferase activity. Involved in several processes, including chondroitin sulfate biosynthetic process; multicellular organism reproduction; and pharynx development. Located in membrane. Human ortholog(s) of this gene implicated in Barrett's esophagus; Larsen-like syndrome B3GAT3 type; and schizophrenia. Is an ortholog of human B3GAT3 (beta-1,3-glucuronyltransferase 3). WB:WBGene00005027 sra-1 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00005028 sra-2 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in body wall musculature; head; and head neurons. WB:WBGene00005029 sra-3 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00005030 sra-4 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in pharynx. WB:WBGene00005031 sra-5 Is affected by etr-1; qui-1; and eri-1 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00005032 sra-6 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Located in cilium. Expressed in head and tail. WB:WBGene00005033 sra-7 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in head and tail. WB:WBGene00005034 sra-8 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00005035 sra-9 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in anchor cell; dorsal uterine cell; and vulval precursor cell. WB:WBGene00005036 sra-10 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in dorsal ganglion; muscle cell; and neurons. WB:WBGene00005037 sra-11 Predicted to enable olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception and olfactory learning. Predicted to be located in membrane. Expressed in VC neuron; interneuron; pharyngeal neurons; and ventral ganglion. WB:WBGene00005038 sra-12 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in ASJL; ASJR; ASKL; and ASKR. WB:WBGene00005039 sra-13 Enables olfactory receptor activity. Involved in several processes, including detection of chemical stimulus involved in sensory perception of smell; negative regulation of response to food; and negative regulation of vulval development. Predicted to be located in membrane. Expressed in amphid neurons; body wall musculature; head; hypodermis; and muscle cell. WB:WBGene00005040 sra-14 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in RID; chemosensory neurons; and ray. WB:WBGene00005041 sra-15 Enriched in AVK based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00005042 sra-16 Is affected by sir-2.1 based on microarray studies. Is affected by Microcystin-LR based on microarray studies. WB:WBGene00005043 sra-17 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ASIL; ASIR; AWAL; AWAR; and neurons. WB:WBGene00005044 sra-18 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005045 sra-19 Is affected by several genes including daf-2; lin-4; and eat-2 based on microarray studies. Is affected by resveratrol; adsorbable organic bromine compound; and Sirolimus based on microarray studies. WB:WBGene00005046 sra-20 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005047 sra-21 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005048 sra-22 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005049 sra-23 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in PQR; head; and neurons. WB:WBGene00005050 sra-24 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005051 sra-25 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head neurons and tail. WB:WBGene00005052 sra-26 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005053 sra-27 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005054 sra-28 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ASIL; ASIR; PQR; and neurons. WB:WBGene00005055 sra-29 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005056 sra-30 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005057 sra-31 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005058 sra-32 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00005059 sra-33 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00005060 sra-34 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00005061 sra-35 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in HSN and head neurons. WB:WBGene00005062 sra-36 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in ASIL; ASIR; DA8; DA9; and VA11. WB:WBGene00005063 sra-37 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00005064 sra-38 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in head. WB:WBGene00005065 sra-39 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in chemosensory neurons. WB:WBGene00005066 srb-1 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005067 srb-2 Enriched in neurons based on RNA-seq studies. Is affected by several genes including clk-1; ain-1; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00005068 srb-3 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in dendrite; perikaryon; and plasma membrane. WB:WBGene00005069 srb-4 Is affected by hmg-4; let-418; and dcp-66 based on RNA-seq studies. Is affected by resveratrol and Sirolimus based on microarray studies. WB:WBGene00005070 srb-5 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in dendrite; perikaryon; and plasma membrane. Expressed in ASKL and ASKR. WB:WBGene00005071 srb-6 Predicted to enable transmembrane signaling receptor activity. Involved in defense response to Gram-positive bacterium and detection of chemical stimulus. Located in cilium. Expressed in chemosensory neurons; head; tail; and uv1. WB:WBGene00005072 srb-7 Expressed in head. WB:WBGene00005073 srb-8 Is affected by several genes including daf-12; lin-4; and lin-14 based on tiling array and microarray studies. Is affected by five chemicals including resveratrol; Atrazine; and Chlorpyrifos based on microarray studies. WB:WBGene00005074 srb-9 Enriched in hypodermis based on RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00005075 srb-10 Is affected by sir-2.1 and ain-1 based on microarray studies. Is affected by four chemicals including resveratrol; Chlorpyrifos; and Diazinon based on microarray studies. WB:WBGene00005076 srb-11 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005077 src-1 Enables netrin receptor binding activity and non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including anatomical structure morphogenesis; axis specification; and establishment of mitotic spindle orientation. Located in contractile fiber and phagocytic cup. Expressed in several structures, including anchor cell; anus; distal tip cell; head neurons; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; diabetes mellitus (multiple); gastrointestinal system cancer (multiple); and lung non-small cell carcinoma (multiple). Is an ortholog of human FYN (FYN proto-oncogene, Src family tyrosine kinase); SRC (SRC proto-oncogene, non-receptor tyrosine kinase); and YES1 (YES proto-oncogene 1, Src family tyrosine kinase). WB:WBGene00005078 src-2 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Involved in pharynx development. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Expressed in anus; pharyngeal muscle cell; and vulva. Is an ortholog of human FRK (fyn related Src family tyrosine kinase). WB:WBGene00005079 srd-1 Predicted to be located in membrane. Expressed in AWAL and AWAR. WB:WBGene00005080 srd-2 Predicted to be located in membrane. WB:WBGene00005081 srd-3 Predicted to be located in membrane. WB:WBGene00005082 srd-4 Predicted to be located in membrane. Expressed in BAGL; BAGR; DA9; motor neurons; and tail neurons. WB:WBGene00005083 srd-5 Predicted to be located in membrane. Expressed in ASIL; ASIR; and AWC-OFF. WB:WBGene00005084 srd-6 No description available WB:WBGene00005085 srd-7 Predicted to be located in membrane. WB:WBGene00005086 srd-8 Predicted to be located in membrane. WB:WBGene00005087 srd-9 Predicted to be located in membrane. WB:WBGene00005088 srd-10 Predicted to be located in membrane. Expressed in chemosensory neurons. WB:WBGene00005089 srd-11 Predicted to be located in membrane. Expressed in AWBL; AWBR; and neurons. WB:WBGene00005090 srd-12 Predicted to be located in membrane. WB:WBGene00005091 srd-13 Predicted to be located in membrane. WB:WBGene00005092 srd-14 Enriched in AWB based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including 1-methylnicotinamide; rotenone; and Zidovudine based on RNA-seq studies. WB:WBGene00005093 srd-15 Predicted to be located in membrane. Expressed in amphid neurons. WB:WBGene00005094 srd-16 Predicted to be located in membrane. Expressed in chemosensory neurons. WB:WBGene00005095 srd-17 Predicted to be located in membrane. Expressed in AWCL and AWCR. WB:WBGene00005096 srd-18 Predicted to be located in membrane. WB:WBGene00005097 srd-19 Predicted to be located in membrane. WB:WBGene00005098 srd-20 Predicted to be located in membrane. WB:WBGene00005099 srd-21 Predicted to be located in membrane. WB:WBGene00005100 srd-22 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00005101 srd-23 Located in neuronal cell body and non-motile cilium. Expressed in ASKL; ASKR; AWBL; and AWBR. WB:WBGene00005102 srd-24 Is affected by clk-1 based on microarray studies. WB:WBGene00005103 srd-25 Predicted to be located in membrane. WB:WBGene00005104 srd-26 Predicted to be located in membrane. WB:WBGene00005105 srd-27 Predicted to be located in membrane. WB:WBGene00005106 srd-28 Involved in short-term memory. Predicted to be located in membrane. WB:WBGene00005107 srd-29 Predicted to be located in membrane. WB:WBGene00005108 srd-30 Predicted to be located in membrane. WB:WBGene00005109 srd-31 Predicted to be located in membrane. WB:WBGene00005110 srd-32 Predicted to be located in membrane. Expressed in several structures, including distal tip cell; enteric muscle; head mesodermal cell; neurons; and pharyngeal-intestinal valve. WB:WBGene00005111 srd-33 Predicted to be located in membrane. Expressed in ASEL; ASER; and neurons. WB:WBGene00005112 srd-34 Predicted to be located in membrane. WB:WBGene00005113 srd-35 Predicted to be located in membrane. WB:WBGene00005114 srd-36 Predicted to be located in membrane. Expressed in ASKL and ASKR. WB:WBGene00005115 srd-37 Is affected by eat-2 and etr-1 based on RNA-seq studies. WB:WBGene00005116 srd-38 Predicted to be located in membrane. WB:WBGene00005117 srd-39 Predicted to be located in membrane. WB:WBGene00005118 srd-40 Predicted to be located in membrane. WB:WBGene00005119 srd-41 Predicted to be located in membrane. WB:WBGene00005120 srd-42 Predicted to be located in membrane. WB:WBGene00005121 srd-43 Predicted to be located in membrane. WB:WBGene00005122 srd-44 Predicted to be located in membrane. WB:WBGene00005123 srd-45 Predicted to be located in membrane. WB:WBGene00005124 srd-46 Predicted to be located in membrane. WB:WBGene00005125 srd-47 Predicted to be located in membrane. WB:WBGene00005126 srd-48 Predicted to be located in membrane. WB:WBGene00005127 srd-49 Predicted to be located in membrane. WB:WBGene00005128 srd-50 Predicted to be located in membrane. WB:WBGene00005129 srd-51 Predicted to be located in membrane. WB:WBGene00005130 srd-52 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00005131 srd-53 Predicted to be located in membrane. WB:WBGene00005132 srd-54 Predicted to be located in membrane. WB:WBGene00005133 srd-55 Predicted to be located in membrane. WB:WBGene00005134 srd-56 Predicted to be located in membrane. WB:WBGene00005135 srd-58 Predicted to be located in membrane. WB:WBGene00005136 srd-59 Predicted to be located in membrane. WB:WBGene00005137 srd-60 Predicted to be located in membrane. WB:WBGene00005138 srd-61 Predicted to be located in membrane. WB:WBGene00005139 srd-62 Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq studies. WB:WBGene00005140 srd-63 Predicted to be located in membrane. WB:WBGene00005141 srd-64 Predicted to be located in membrane. WB:WBGene00005142 srd-65 Predicted to be located in membrane. WB:WBGene00005143 srd-66 Predicted to be located in membrane. WB:WBGene00005144 srd-67 Predicted to be located in membrane. WB:WBGene00005145 srd-68 Predicted to be located in membrane. WB:WBGene00005146 srd-69 Predicted to be located in membrane. WB:WBGene00005147 srd-70 Predicted to be located in membrane. WB:WBGene00005148 srd-71 Predicted to be located in membrane. WB:WBGene00005149 sre-1 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in neurons. WB:WBGene00005150 sre-2 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in plasma membrane. WB:WBGene00005151 srf-1 Used to study bacterial infectious disease. WB:WBGene00005152 srf-2 Used to study bacterial infectious disease. WB:WBGene00005153 srf-3 Enables UDP-N-acetylglucosamine transmembrane transporter activity and UDP-galactose transmembrane transporter activity. Involved in UDP-N-acetylglucosamine transmembrane transport and UDP-galactose transmembrane transport. Located in Golgi membrane and perinuclear region of cytoplasm. Expressed in pharyngeal gland cell; seam cell; spermatheca; and vas deferens. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIm. Is an ortholog of human SLC35A2 (solute carrier family 35 member A2). WB:WBGene00005154 srf-4 No description available WB:WBGene00005155 srf-5 No description available WB:WBGene00005156 srf-6 No description available WB:WBGene00005157 srf-8 No description available WB:WBGene00005158 srf-9 No description available WB:WBGene00005159 srg-1 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005160 srg-2 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005161 srg-3 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005162 srg-4 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ASIL; ASIR; ASKL; ASKR; and PVT. WB:WBGene00005163 srg-5 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head neurons and ray. WB:WBGene00005164 srg-6 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005165 srg-7 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head. WB:WBGene00005166 srg-8 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005167 srg-9 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head; neurons; and tail. WB:WBGene00005168 srg-10 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005169 srg-11 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005170 srg-13 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005171 srg-14 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head neurons; tail; and in male. WB:WBGene00005172 srg-15 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005173 srg-16 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005174 srg-17 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005175 srg-18 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by clk-1; sir-2.1; and rrf-3 based on microarray studies. WB:WBGene00005176 srg-19 Is affected by several genes including rrf-3; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00005177 srg-20 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005178 srg-21 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005179 srg-22 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005180 srg-23 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005181 srg-24 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005182 srg-25 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ciliated neurons. WB:WBGene00005183 srg-26 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005184 srg-27 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005185 srg-28 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005186 srg-29 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ASIL; ASIR; head muscle; neurons; and pharynx. WB:WBGene00005187 srg-30 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ASEL; ASER; and neurons. WB:WBGene00005188 srg-31 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in amphid neurons; anal depressor muscle; and lumbar neurons. WB:WBGene00005189 srg-32 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ganglia. WB:WBGene00005190 srg-33 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ASIL and ASIR. WB:WBGene00005191 srg-34 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005192 srg-35 Is affected by eat-2; etr-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00005193 srg-36 Predicted to enable transmembrane signaling receptor activity. Involved in dauer larval development. Located in non-motile cilium. Expressed in ASIL; ASIR; and neurons. WB:WBGene00005194 srg-37 Predicted to enable transmembrane signaling receptor activity. Involved in dauer larval development. Predicted to be located in membrane. Expressed in ASIL and ASIR. WB:WBGene00005195 srg-38 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005196 srg-39 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ASIL; ASIR; PVT; intestine; and pharynx. WB:WBGene00005197 srg-40 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005198 srg-41 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in nervous system and tail neurons. WB:WBGene00005199 srg-42 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005200 srg-43 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00005201 srg-44 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005202 srg-45 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005203 srg-46 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005204 srg-47 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Located in cilium. Expressed in ASIL and ASIR. WB:WBGene00005205 srg-48 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005206 srg-49 Is affected by several genes including daf-16; wdr-23; and smn-1 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00005207 srg-50 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005208 srg-51 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005210 srg-53 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005211 srg-54 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005212 srg-55 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005213 srg-56 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005214 srg-57 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005215 srg-58 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in AIML; AIMR; ASIL; and ASIR. WB:WBGene00005216 srg-59 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005217 srg-60 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005218 srg-61 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005219 srg-62 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005220 srg-63 Is affected by dafa#1 based on microarray studies. WB:WBGene00005221 srg-64 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head neurons. WB:WBGene00005222 srg-65 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005223 srg-66 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ASIL and ASIR. WB:WBGene00005224 srg-67 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005225 srg-68 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005226 srg-69 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005227 srh-1 Predicted to be located in membrane. WB:WBGene00005228 srh-2 Predicted to be located in membrane. Expressed in several structures, including Eala; Ealp; Eara; Earp; and intestine. WB:WBGene00005229 srh-3 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005230 srh-4 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005231 srh-5 Predicted to be located in membrane. Expressed in ADLL; ADLR; ASHL; and ASHR. WB:WBGene00005232 srh-6 Is affected by daf-2; eat-2; and mrps-5 based on microarray studies. WB:WBGene00005233 srh-7 Predicted to be located in membrane. Expressed in head neurons; intestine; and pharynx. WB:WBGene00005234 srh-8 Predicted to be located in membrane. WB:WBGene00005235 srh-9 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; dpy-21; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00005236 srh-10 Predicted to be located in membrane. Expressed in ASHL; ASHR; ASJL; and ASJR. WB:WBGene00005237 srh-11 Predicted to be located in membrane. Expressed in several structures, including PQR; PVT; head muscle; lateral ganglion; and ray. WB:WBGene00005238 srh-12 No description available WB:WBGene00005239 srh-13 No description available WB:WBGene00005240 srh-15 Predicted to be located in membrane. Expressed in chemosensory neurons and nerve ring neurons. WB:WBGene00005241 srh-16 Predicted to be located in membrane. WB:WBGene00005242 srh-17 Predicted to be located in membrane. WB:WBGene00005243 srh-18 Predicted to be located in membrane. Expressed in chemosensory neurons. WB:WBGene00005244 srh-19 Predicted to be located in membrane. WB:WBGene00005245 srh-20 Predicted to be located in membrane. WB:WBGene00005246 srh-21 Predicted to be located in membrane. WB:WBGene00005247 srh-22 Predicted to be located in membrane. WB:WBGene00005248 srh-23 Predicted to be located in membrane. WB:WBGene00005249 srh-25 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005250 srh-27 Predicted to be located in membrane. WB:WBGene00005251 srh-28 Predicted to be located in membrane. Expressed in ASHL; ASHR; ASJL; and ASJR. WB:WBGene00005252 srh-29 Is affected by etr-1 based on RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00005253 srh-30 Predicted to be located in membrane. WB:WBGene00005254 srh-31 Predicted to be located in membrane. WB:WBGene00005255 srh-32 Predicted to be located in membrane. WB:WBGene00005256 srh-33 Predicted to be located in membrane. WB:WBGene00005257 srh-34 Predicted to be located in membrane. WB:WBGene00005258 srh-35 Predicted to be located in membrane. WB:WBGene00005259 srh-36 Predicted to be located in membrane. WB:WBGene00005260 srh-37 Predicted to be located in membrane. WB:WBGene00005261 srh-38 Predicted to be located in membrane. WB:WBGene00005262 srh-39 Predicted to be located in membrane. WB:WBGene00005263 srh-40 Predicted to be located in membrane. WB:WBGene00005264 srh-41 Predicted to be located in membrane. WB:WBGene00005265 srh-42 Predicted to be located in membrane. WB:WBGene00005266 srh-43 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00005267 srh-44 Predicted to be located in membrane. WB:WBGene00005268 srh-45 Predicted to be located in membrane. WB:WBGene00005269 srh-46 Predicted to be located in membrane. WB:WBGene00005270 srh-47 Predicted to be located in membrane. WB:WBGene00005271 srh-48 Predicted to be located in membrane. WB:WBGene00005272 srh-49 Predicted to be located in membrane. WB:WBGene00005273 srh-50 Predicted to be located in membrane. WB:WBGene00005274 srh-51 Predicted to be located in membrane. WB:WBGene00005275 srh-52 Predicted to be located in membrane. WB:WBGene00005276 srh-53 No description available WB:WBGene00005277 srh-54 Enriched in neurons based on microarray studies. Is affected by several genes including eat-2; tph-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00005278 srh-55 Predicted to be located in membrane. WB:WBGene00005279 srh-56 Predicted to be located in membrane. Expressed in amphid neurons. WB:WBGene00005280 srh-57 Predicted to be located in membrane. WB:WBGene00005281 srh-59 Predicted to be located in membrane. WB:WBGene00005282 srh-60 Predicted to be located in membrane. WB:WBGene00005283 srh-61 Predicted to be located in membrane. WB:WBGene00005284 srh-62 Predicted to be located in membrane. Expressed in OLL and neurons. WB:WBGene00005285 srh-63 Predicted to be located in membrane. WB:WBGene00005286 srh-65 Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. WB:WBGene00005287 srh-66 Is affected by tatn-1 and clk-1 based on RNA-seq and microarray studies. WB:WBGene00005288 srh-67 Predicted to be located in membrane. WB:WBGene00005289 srh-68 Predicted to be located in membrane. Expressed in ADLL; ADLR; and neurons. WB:WBGene00005290 srh-69 Predicted to be located in membrane. WB:WBGene00005291 srh-70 Predicted to be located in membrane. WB:WBGene00005292 srh-71 Predicted to be located in membrane. Expressed in neurons; pharynx; and ray. WB:WBGene00005293 srh-72 Predicted to be located in membrane. WB:WBGene00005294 srh-73 Predicted to be located in membrane. WB:WBGene00005295 srh-74 Predicted to be located in membrane. Expressed in AWA and chemosensory neurons. WB:WBGene00005296 srh-75 Predicted to be located in membrane. WB:WBGene00005297 srh-76 Predicted to be located in membrane. Expressed in head neurons. WB:WBGene00005298 srh-77 Is affected by mex-3 and sir-2.1 based on RNA-seq and microarray studies. Is affected by aldicarb based on microarray studies. WB:WBGene00005299 srh-78 Predicted to be located in membrane. WB:WBGene00005300 srh-79 Predicted to be located in membrane. Expressed in chemosensory neurons. WB:WBGene00005301 srh-80 Predicted to be located in membrane. WB:WBGene00005302 srh-81 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol; Colistin; and nitroguanidine based on microarray studies. WB:WBGene00005303 srh-82 Predicted to be located in membrane. WB:WBGene00005304 srh-83 Predicted to be located in membrane. WB:WBGene00005305 srh-84 Is affected by etr-1; sir-2.1; and let-60 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00005306 srh-85 Predicted to be located in membrane. WB:WBGene00005307 srh-86 Is affected by several genes including lin-4; lin-14; and clk-1 based on microarray and RNA-seq studies. WB:WBGene00005308 srh-87 Predicted to be located in membrane. WB:WBGene00005309 srh-88 Predicted to be located in membrane. WB:WBGene00005310 srh-89 Predicted to be located in membrane. WB:WBGene00005311 srh-90 Enriched in CAN based on single-cell RNA-seq studies. Is affected by clk-1; daf-2; and eat-2 based on microarray studies. Is affected by dibromoacetic acid and adsorbable organic bromine compound based on microarray studies. WB:WBGene00005312 srh-91 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00005313 srh-92 Predicted to be located in membrane. WB:WBGene00005314 srh-93 Is affected by clk-1 based on microarray studies. WB:WBGene00005315 srh-95 Predicted to be located in membrane. WB:WBGene00005316 srh-97 Predicted to be located in membrane. WB:WBGene00005317 srh-98 Predicted to be located in membrane. WB:WBGene00005318 srh-99 Predicted to be located in membrane. WB:WBGene00005319 srh-100 Predicted to be located in membrane. Expressed in ASIL; ASIR; ASJL; ASJR; and ventral ganglion. WB:WBGene00005320 srh-101 Enriched in PHA based on single-cell RNA-seq studies. Is affected by clk-1; etr-1; and sir-2.1 based on microarray and RNA-seq studies. WB:WBGene00005321 srh-102 Predicted to be located in membrane. WB:WBGene00005322 srh-103 Is affected by tdp-1 based on microarray studies. WB:WBGene00005323 srh-104 Predicted to be located in membrane. WB:WBGene00005324 T27A1.1 Predicted to be located in membrane. WB:WBGene00005325 srh-106 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00005326 srh-107 Is affected by several genes including eat-2; let-418; and chd-3 based on RNA-seq and microarray studies. Is affected by dibromoacetic acid based on microarray studies. WB:WBGene00005327 srh-108 Enriched in neurons based on microarray studies. Is affected by etr-1; lpd-3; and lin-52 based on RNA-seq studies. Is affected by Sirolimus and allantoin based on microarray studies. WB:WBGene00005328 srh-109 Predicted to be located in membrane. WB:WBGene00005329 srh-110 Is affected by several genes including daf-2; rrf-3; and sir-2.1 based on microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies. WB:WBGene00005330 srh-111 Predicted to be located in membrane. WB:WBGene00005331 srh-112 Predicted to be located in membrane. WB:WBGene00005332 srh-113 Predicted to be located in membrane. WB:WBGene00005333 srh-114 Is affected by smn-1 and etr-1 based on RNA-seq studies. WB:WBGene00005334 srh-115 Predicted to be located in membrane. WB:WBGene00005335 srh-116 Predicted to be located in membrane. WB:WBGene00005336 srh-117 Is affected by several genes including sir-2.1; clk-1; and mut-2 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00005337 srh-118 Predicted to be located in membrane. WB:WBGene00005338 srh-119 Predicted to be located in membrane. WB:WBGene00005339 srh-120 Predicted to be located in membrane. WB:WBGene00005340 srh-122 Predicted to be located in membrane. WB:WBGene00005341 srh-123 Predicted to be located in membrane. WB:WBGene00005342 srh-125 Predicted to be located in membrane. WB:WBGene00005343 srh-126 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies. WB:WBGene00005344 srh-127 Predicted to be located in membrane. Expressed in pharyngeal neurons and sensory neurons. WB:WBGene00005345 srh-128 Predicted to be located in membrane. WB:WBGene00005346 srh-129 Predicted to be located in membrane. WB:WBGene00005347 srh-130 Predicted to be located in membrane. Expressed in head neurons; sensory neurons; and vulval cell. WB:WBGene00005348 srh-131 Predicted to be located in membrane. WB:WBGene00005349 srh-132 Predicted to be located in membrane. Expressed in ADLL; ADLR; and head mesodermal cell. WB:WBGene00005350 srh-133 Predicted to be located in membrane. WB:WBGene00005351 srh-134 Predicted to be located in membrane. WB:WBGene00005352 srh-135 Predicted to be located in membrane. WB:WBGene00005353 srh-136 Predicted to be located in membrane. WB:WBGene00005354 srh-137 Predicted to be located in membrane. WB:WBGene00005355 srh-138 Predicted to be located in membrane. WB:WBGene00005356 srh-139 Predicted to be located in membrane. Expressed in ADLL; ADLR; and neurons. WB:WBGene00005357 srh-140 Predicted to be located in membrane. WB:WBGene00005358 srh-141 Predicted to be located in membrane. WB:WBGene00005359 srh-142 Predicted to be located in membrane. Expressed in chemosensory neurons and pharynx. WB:WBGene00005360 srh-144 Is affected by clk-1; adr-1; and eat-2 based on microarray and RNA-seq studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00005361 srh-145 Predicted to be located in membrane. WB:WBGene00005362 srh-146 Predicted to be located in membrane. WB:WBGene00005363 srh-147 Predicted to be located in membrane. WB:WBGene00005364 srh-148 Predicted to be located in membrane. WB:WBGene00005365 srh-149 Predicted to be located in membrane. WB:WBGene00005366 srh-150 Enriched in ADL and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including sir-2.1; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00005367 srh-151 Is affected by etr-1 based on RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00005368 srh-152 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00005369 srh-153 Is affected by sir-2.1 based on microarray studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00005370 srh-154 Predicted to be located in membrane. WB:WBGene00005371 srh-155 Is affected by rsr-2; drh-3; and etr-1 based on tiling array and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00005372 srh-156 Is affected by sir-2.1 based on microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00005373 srh-157 Is affected by cyc-1; clk-1; and rrf-1 based on microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00005374 srh-158 Is affected by daf-16; bet-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00005375 srh-159 Predicted to be located in membrane. WB:WBGene00005376 srh-160 Is affected by several genes including daf-2; let-60; and sir-2.1 based on microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00005377 srh-161 No description available WB:WBGene00005378 srh-162 Is affected by clk-1 based on microarray studies. WB:WBGene00005379 srh-163 Is affected by several genes including skn-1; clk-1; and alg-1 based on microarray and RNA-seq studies. Is affected by Rifampin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00005380 srh-164 Is affected by etr-1 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00005381 srh-165 Is affected by several genes including eat-2; mut-2; and mir-34 based on tiling array and microarray studies. Is affected by allantoin and Sirolimus based on microarray studies. WB:WBGene00005382 srh-166 Predicted to be located in membrane. WB:WBGene00005383 srh-167 Predicted to be located in membrane. WB:WBGene00005384 srh-168 Is affected by sir-2.1 based on microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00005385 srh-169 Predicted to be located in membrane. WB:WBGene00005386 srh-170 Predicted to be located in membrane. WB:WBGene00005387 srh-171 Predicted to be located in membrane. WB:WBGene00005388 srh-172 Predicted to be located in membrane. WB:WBGene00005389 srh-173 Predicted to be located in membrane. WB:WBGene00005390 srh-174 Predicted to be located in membrane. WB:WBGene00005391 srh-175 Enriched in muscle cell and neurons based on microarray studies. Is affected by several genes including eat-2; sir-2.1; and qui-1 based on RNA-seq and microarray studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00005392 srh-177 Predicted to be located in membrane. WB:WBGene00005393 srh-178 Predicted to be located in membrane. WB:WBGene00005394 srh-179 Predicted to be located in membrane. WB:WBGene00005395 srh-180 Predicted to be located in membrane. WB:WBGene00005396 srh-181 Predicted to be located in membrane. WB:WBGene00005397 srh-182 Predicted to be located in membrane. Expressed in neurons. WB:WBGene00005398 srh-183 Predicted to be located in membrane. WB:WBGene00005399 srh-184 Predicted to be located in membrane. WB:WBGene00005400 srh-185 Predicted to be located in membrane. WB:WBGene00005401 srh-186 Predicted to be located in membrane. WB:WBGene00005402 srh-187 Predicted to be located in membrane. WB:WBGene00005403 srh-189 Is affected by several genes including daf-16; daf-12; and lin-4 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00005404 srh-190 Predicted to be located in membrane. WB:WBGene00005405 srh-192 Predicted to be located in membrane. WB:WBGene00005406 srh-193 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005407 srh-194 Predicted to be located in membrane. WB:WBGene00005408 srh-195 Predicted to be located in membrane. WB:WBGene00005409 srh-198 Is affected by eat-2 and adr-2 based on RNA-seq studies. Is affected by Psoralens and allantoin based on RNA-seq studies. WB:WBGene00005410 srh-199 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005411 srh-200 Predicted to be located in membrane. WB:WBGene00005412 srh-201 Predicted to be located in membrane. Expressed in amphid neurons; pharynx; and tail neurons. WB:WBGene00005413 srh-202 Is affected by etr-1 based on RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00005414 srh-203 Predicted to be located in membrane. WB:WBGene00005415 srh-204 Predicted to be located in membrane. WB:WBGene00005416 srh-206 Predicted to be located in membrane. WB:WBGene00005417 srh-207 Predicted to be located in membrane. WB:WBGene00005418 srh-208 Predicted to be located in membrane. WB:WBGene00005419 srh-209 Predicted to be located in membrane. WB:WBGene00005420 srh-210 Expressed in several structures, including ASH; head mesodermal cell; pharyngeal-intestinal valve; retrovesicular ganglion; and vulva. WB:WBGene00005421 srh-211 Predicted to be located in membrane. Expressed in PHA and amphid neurons. WB:WBGene00005422 srh-212 Predicted to be located in membrane. WB:WBGene00005423 srh-213 Predicted to be located in membrane. WB:WBGene00005424 srh-214 Predicted to be located in membrane. WB:WBGene00005425 srh-215 Predicted to be located in membrane. WB:WBGene00005426 srh-216 Predicted to be located in membrane. WB:WBGene00005427 srh-217 Predicted to be located in membrane. WB:WBGene00005428 srh-218 Predicted to be located in membrane. Expressed in chemosensory neurons and head. WB:WBGene00005429 srh-219 Predicted to be located in membrane. WB:WBGene00005430 srh-220 Predicted to be located in membrane. WB:WBGene00005431 srh-221 Is affected by dpy-21 and etr-1 based on RNA-seq studies. Is affected by nitroguanidine based on microarray studies. WB:WBGene00005432 srh-222 Predicted to be located in membrane. WB:WBGene00005433 srh-223 Predicted to be located in membrane. WB:WBGene00005434 srh-224 Is affected by sir-2.1 based on microarray studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00005435 srh-227 Predicted to be located in membrane. WB:WBGene00005436 srh-228 Is affected by several genes including sir-2.1; csr-1; and mir-34 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Serpentine type 7TM GPCR chemoreceptor Srh and 7TM GPCR, serpentine receptor class h (Srh). WB:WBGene00005437 srh-229 Predicted to be located in membrane. WB:WBGene00005438 srh-230 Enriched in ADL; ASH; and PHA based on single-cell RNA-seq studies. Is affected by several genes including daf-12; hpl-2; and dpy-21 based on RNA-seq and microarray studies. WB:WBGene00005439 srh-231 Predicted to be located in membrane. WB:WBGene00005440 srh-233 Predicted to be located in membrane. WB:WBGene00005441 srh-234 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in cilium. Expressed in ADLL and ADLR. WB:WBGene00005442 srh-235 Predicted to be located in membrane. WB:WBGene00005443 srh-236 Predicted to be located in membrane. WB:WBGene00005444 srh-237 Predicted to be located in membrane. WB:WBGene00005445 srh-238 Is affected by several genes including sir-2.1; qui-1; and adr-1 based on RNA-seq and microarray studies. Is affected by dafa#1 and adsorbable organic bromine compound based on microarray studies. WB:WBGene00005446 srh-239 Predicted to be located in membrane. WB:WBGene00005447 srh-240 Predicted to be located in membrane. WB:WBGene00005448 srh-241 Predicted to be located in membrane. Expressed in ASIL; ASIR; ASKL; ASKR; and intestine. WB:WBGene00005449 srh-243 Predicted to be located in membrane. WB:WBGene00005450 srh-244 Predicted to be located in membrane. WB:WBGene00005451 srh-245 Predicted to be located in membrane. WB:WBGene00005452 srh-246 Predicted to be located in membrane. WB:WBGene00005453 srh-247 Predicted to be located in membrane. WB:WBGene00005454 srh-248 Predicted to be located in membrane. WB:WBGene00005455 srh-249 Is affected by clk-1 based on microarray studies. WB:WBGene00005456 srh-250 Predicted to be located in membrane. WB:WBGene00005457 srh-251 Predicted to be located in membrane. WB:WBGene00005458 srh-252 Predicted to be located in membrane. WB:WBGene00005459 srh-253 Is affected by sir-2.1 based on microarray studies. Is affected by Chlorpyrifos and nitroguanidine based on microarray studies. WB:WBGene00005460 srh-254 Is affected by lpd-3; sir-2.1; and let-60 based on RNA-seq and microarray studies. Is affected by resveratrol and adsorbable organic bromine compound based on microarray studies. WB:WBGene00005461 srh-255 Predicted to be located in membrane. WB:WBGene00005462 srh-256 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00005463 srh-257 Predicted to be located in membrane. WB:WBGene00005464 srh-258 Predicted to be located in membrane. WB:WBGene00005465 srh-259 No description available WB:WBGene00005466 srh-260 Is affected by sir-2.1 based on microarray studies. WB:WBGene00005467 srh-261 Is affected by several genes including eat-2; clk-1; and mex-1 based on tiling array; microarray; and RNA-seq studies. Is affected by allantoin based on microarray studies. WB:WBGene00005468 srh-262 Is affected by several genes including sir-2.1; clk-1; and let-418 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00005469 srh-263 Is affected by daf-2 based on microarray studies. Is affected by Diazinon based on microarray studies. WB:WBGene00005470 srh-264 Predicted to be located in membrane. WB:WBGene00005471 srh-265 Predicted to be located in membrane. WB:WBGene00005472 srh-266 Predicted to be located in membrane. Expressed in ADLL; ADLR; and seam cell. WB:WBGene00005473 srh-267 Is affected by etr-1 and qui-1 based on RNA-seq studies. WB:WBGene00005474 srh-268 Predicted to be located in membrane. WB:WBGene00005475 srh-269 Predicted to be located in membrane. Expressed in chemosensory neurons; coelomocyte; and pharyngeal cell. WB:WBGene00005476 srh-270 Predicted to be located in membrane. Expressed in amphid sensillum; chemosensory neurons; head ganglion; ray; and vulva. WB:WBGene00005477 srh-271 Predicted to be located in membrane. WB:WBGene00005478 srh-272 Predicted to be located in membrane. WB:WBGene00005479 srh-274 Predicted to be located in membrane. WB:WBGene00005480 srh-275 Predicted to be located in membrane. WB:WBGene00005481 srh-276 Predicted to be located in membrane. WB:WBGene00005482 srh-277 Predicted to be located in membrane. Expressed in AINL; AINR; PVQL; PVQR; and neurons. WB:WBGene00005483 srh-278 Enriched in NSM based on tiling array studies. Is affected by several genes including lin-4; eat-2; and lin-14 based on tiling array; RNA-seq; and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00005484 srh-279 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005485 srh-280 Is affected by several genes including let-60; sir-2.1; and qui-1 based on RNA-seq and microarray studies. WB:WBGene00005486 srh-281 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005487 srh-282 Predicted to be located in membrane. WB:WBGene00005488 srh-283 Predicted to be located in membrane. WB:WBGene00005489 srh-284 Predicted to be located in membrane. WB:WBGene00005490 srh-286 Predicted to be located in membrane. WB:WBGene00005491 srh-287 Predicted to be located in membrane. WB:WBGene00005492 srh-288 Predicted to be located in membrane. WB:WBGene00005493 srh-289 Predicted to be located in membrane. WB:WBGene00005494 srh-290 Predicted to be located in membrane. WB:WBGene00005495 srh-291 Predicted to be located in membrane. WB:WBGene00005496 srh-292 Predicted to be located in membrane. WB:WBGene00005497 srh-293 Predicted to be located in membrane. WB:WBGene00005498 srh-294 Is affected by eat-2 based on RNA-seq studies. Is affected by metformin and Sirolimus based on RNA-seq studies. WB:WBGene00005499 srh-295 Predicted to be located in membrane. WB:WBGene00005500 srh-296 Predicted to be located in membrane. WB:WBGene00005501 srh-297 Predicted to be located in membrane. WB:WBGene00005502 srh-298 Predicted to be located in membrane. WB:WBGene00005503 srh-299 Predicted to be located in membrane. WB:WBGene00005504 srh-300 Predicted to be located in membrane. WB:WBGene00005505 srh-301 Predicted to be located in membrane. WB:WBGene00005506 srh-302 Is affected by cyc-1 based on microarray studies. WB:WBGene00005507 srh-303 Predicted to be located in membrane. WB:WBGene00005508 srh-304 Predicted to be located in membrane. WB:WBGene00005509 srh-305 Is affected by clk-1 and etr-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Serpentine type 7TM GPCR chemoreceptor Srh and 7TM GPCR, serpentine receptor class h (Srh). WB:WBGene00005510 srh-306 No description available WB:WBGene00005511 srh-307 Enriched in ASJ and muscle cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including eat-2; pgl-1; and eri-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00005512 srh-105 Predicted to be located in membrane. WB:WBGene00005513 sri-1 Predicted to be located in membrane. Expressed in OLL; head mesodermal cell; and interneuron. WB:WBGene00005514 sri-2 Predicted to be located in membrane. WB:WBGene00005515 sri-3 No description available WB:WBGene00005516 sri-4 Predicted to be located in membrane. WB:WBGene00005517 sri-5 Predicted to be located in membrane. Expressed in chemosensory neurons; egg-laying apparatus; pharynx; and ventral nerve cord. WB:WBGene00005518 sri-6 Predicted to be located in membrane. WB:WBGene00005519 sri-7 Predicted to be located in membrane. WB:WBGene00005520 sri-8 Enriched in germ line based on RNA-seq studies. Is affected by several genes including nhr-49; hpl-2; and qui-1 based on RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00005521 sri-9 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005522 sri-10 Predicted to be located in membrane. WB:WBGene00005523 sri-11 Predicted to be located in membrane. WB:WBGene00005524 sri-12 Predicted to be located in membrane. Expressed in ganglia. WB:WBGene00005525 sri-13 Predicted to be located in membrane. WB:WBGene00005526 sri-14 Involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Expressed in ASHL; ASHR; AWCL; and AWCR. WB:WBGene00005527 sri-15 Predicted to be located in membrane. WB:WBGene00005528 sri-16 Predicted to be located in membrane. WB:WBGene00005529 sri-17 Predicted to be located in membrane. WB:WBGene00005530 sri-18 Predicted to be located in membrane. Expressed in ADE and interneuron. WB:WBGene00005531 sri-19 Predicted to be located in membrane. Expressed in body wall musculature; head neurons; and vulval muscle. WB:WBGene00005532 sri-20 Predicted to be located in membrane. WB:WBGene00005533 sri-21 Predicted to be located in membrane. Expressed in RMD and chemosensory neurons. WB:WBGene00005534 sri-22 Is affected by ham-3 and daf-2 based on RNA-seq and microarray studies. Is affected by Colistin based on microarray studies. WB:WBGene00005535 sri-23 Is affected by several genes including sid-1; nhr-49; and hpl-2 based on RNA-seq studies. WB:WBGene00005536 sri-24 Predicted to be located in membrane. WB:WBGene00005537 sri-25 Predicted to be located in membrane. WB:WBGene00005538 sri-26 Predicted to be located in membrane. Expressed in chemosensory neurons. WB:WBGene00005539 sri-27 Predicted to be located in membrane. Expressed in intestine. WB:WBGene00005540 sri-28 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005541 sri-29 Predicted to be located in membrane. WB:WBGene00005542 sri-30 Predicted to be located in membrane. WB:WBGene00005543 sri-31 Predicted to be located in membrane. WB:WBGene00005544 sri-32 Predicted to be located in membrane. WB:WBGene00005545 sri-33 Predicted to be located in membrane. WB:WBGene00005546 sri-34 Predicted to be located in membrane. WB:WBGene00005547 sri-35 Is affected by several genes including sir-2.1; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00005548 sri-36 Predicted to be located in membrane. Expressed in PVT; head ganglion; pharyngeal-intestinal valve; and pharynx. WB:WBGene00005549 sri-37 Predicted to be located in membrane. WB:WBGene00005550 sri-38 Predicted to be located in membrane. WB:WBGene00005551 sri-39 Predicted to be located in membrane. Expressed in neurons. WB:WBGene00005552 sri-40 Predicted to be located in membrane. WB:WBGene00005553 sri-41 Enriched in neurons based on microarray studies. Is affected by qui-1; mut-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00005554 sri-42 Predicted to be located in membrane. WB:WBGene00005555 sri-43 Predicted to be located in membrane. WB:WBGene00005556 sri-44 Is affected by several genes including eat-2; cnd-1; and adr-1 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00005557 sri-45 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005558 sri-46 Predicted to be located in membrane. WB:WBGene00005559 sri-47 Predicted to be located in membrane. WB:WBGene00005560 sri-48 Predicted to be located in membrane. WB:WBGene00005561 sri-49 Is affected by several genes including eat-2; ifg-1; and adr-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00005562 sri-50 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005563 sri-51 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005564 sri-52 Is affected by cyc-1 and eat-2 based on microarray and RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00005565 sri-53 Predicted to be located in membrane. WB:WBGene00005566 sri-54 Predicted to be located in membrane. WB:WBGene00005567 sri-55 Is affected by several genes including isp-1; cyc-1; and rpn-10 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00005568 sri-56 Enriched in ASK based on single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and hda-2 based on microarray and RNA-seq studies. WB:WBGene00005569 sri-57 Predicted to be located in membrane. WB:WBGene00005570 sri-58 Is affected by adr-1; etr-1; and lpd-3 based on RNA-seq studies. WB:WBGene00005571 sri-59 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00005572 sri-60 Predicted to be located in membrane. WB:WBGene00005573 sri-61 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005574 sri-62 Predicted to be located in membrane. Expressed in ADLL; ADLR; and intestine. WB:WBGene00005575 sri-63 Predicted to be located in membrane. WB:WBGene00005576 sri-64 Is affected by hmg-3 and sir-2.1 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00005577 sri-65 Predicted to be located in membrane. WB:WBGene00005578 sri-66 Predicted to be located in membrane. WB:WBGene00005579 sri-67 Predicted to be located in membrane. WB:WBGene00005580 sri-68 Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00005581 sri-69 Predicted to be located in membrane. WB:WBGene00005582 sri-70 Predicted to be located in membrane. WB:WBGene00005583 sri-71 Predicted to be located in membrane. WB:WBGene00005584 sri-72 Predicted to be located in membrane. WB:WBGene00005585 sri-73 Predicted to be located in membrane. WB:WBGene00005586 sri-74 Predicted to be located in membrane. WB:WBGene00005587 sri-75 Is affected by several genes including sir-2.1; unc-30; and alg-1 based on RNA-seq and microarray studies. WB:WBGene00005588 sri-76 Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by Progesterone and Sirolimus based on microarray studies. WB:WBGene00005589 sri-77 Predicted to be located in membrane. WB:WBGene00005590 sri-78 Predicted to be located in membrane. WB:WBGene00005591 srj-1 Predicted to be located in membrane. WB:WBGene00005592 srj-4 Predicted to be located in membrane. Expressed in coelomocyte; neurons; and pharynx. WB:WBGene00005593 srj-5 Predicted to be located in membrane. Expressed in ASIL; ASIR; PVT; and pharynx. WB:WBGene00005594 srj-6 Predicted to be located in membrane. WB:WBGene00005595 srj-7 Predicted to be located in membrane. WB:WBGene00005596 srj-8 Predicted to be located in membrane. WB:WBGene00005597 srj-9 Predicted to be located in membrane. WB:WBGene00005598 srj-10 Predicted to be located in membrane. WB:WBGene00005599 srj-11 Predicted to be located in membrane. WB:WBGene00005600 srj-12 Is affected by clk-1 and wdr-23 based on microarray and RNA-seq studies. WB:WBGene00005601 srj-13 Predicted to be located in membrane. Expressed in intestine; neurons; pharynx; ventral ganglion; and vulval muscle. WB:WBGene00005602 srj-14 Predicted to be located in membrane. WB:WBGene00005603 srj-15 Predicted to be located in membrane. WB:WBGene00005604 srj-16 Enriched in GABAergic neurons and sensory neurons based on tiling array and RNA-seq studies. Is affected by rsr-2; clk-1; and tdp-1 based on tiling array and microarray studies. Is affected by four chemicals including dibromoacetic acid; tetrabromobisphenol A; and Microcystin-LR based on microarray studies. WB:WBGene00005605 srj-17 Is affected by clk-1; hda-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by estrogen and resveratrol based on microarray studies. WB:WBGene00005606 srj-18 Predicted to be located in membrane. WB:WBGene00005607 srj-19 Predicted to be located in membrane. WB:WBGene00005608 srj-20 Predicted to be located in membrane. Expressed in ASIL; ASIR; PVT; neurons; and seam cell. WB:WBGene00005609 srj-21 Predicted to be located in membrane. Expressed in CP neuron and odorsensory neurons. WB:WBGene00005610 srj-22 Predicted to be located in membrane. Expressed in CP neuron and odorsensory neurons. WB:WBGene00005611 srj-23 Predicted to be located in membrane. Expressed in ASIL; ASIR; and intestine. WB:WBGene00005612 srj-24 Predicted to be located in membrane. Expressed in hypodermis and neurons. WB:WBGene00005613 srj-25 Predicted to be located in membrane. Expressed in ASIL; ASIR; and ventral ganglion. WB:WBGene00005614 srj-26 Predicted to be located in membrane. WB:WBGene00005615 srj-27 Predicted to be located in membrane. Expressed in PVT; head neurons; and ray. WB:WBGene00005616 srj-29 Predicted to be located in membrane. WB:WBGene00005617 srj-32 Predicted to be located in membrane. WB:WBGene00005618 srj-33 Predicted to be located in membrane. WB:WBGene00005619 srj-34 Is affected by clk-1 and eat-2 based on microarray and RNA-seq studies. Is affected by metformin; Sirolimus; and tetrabromobisphenol A based on RNA-seq and microarray studies. WB:WBGene00005620 srj-35 Is affected by hpl-2 and swsn-1 based on RNA-seq studies. WB:WBGene00005621 srj-37 Predicted to be located in membrane. WB:WBGene00005622 srj-38 Predicted to be located in membrane. Expressed in neurons; pharynx; somatic nervous system; and in male. WB:WBGene00005623 srj-39 Predicted to be located in membrane. WB:WBGene00005624 srj-40 Predicted to be located in membrane. WB:WBGene00005625 srj-42 Predicted to be located in membrane. WB:WBGene00005626 srj-44 Predicted to be located in membrane. Expressed in head neurons. WB:WBGene00005627 srj-45 Predicted to be located in membrane. Expressed in AVM; amphid neurons; head neurons; and seam cell. WB:WBGene00005628 srj-49 Predicted to be located in membrane. WB:WBGene00005629 srj-50 Predicted to be located in membrane. WB:WBGene00005630 srj-51 Is affected by several genes including eat-2; sir-2.1; and tph-1 based on RNA-seq and microarray studies. WB:WBGene00005631 srj-52 Predicted to be located in membrane. WB:WBGene00005632 srj-53 Predicted to be located in membrane. WB:WBGene00005633 srj-54 Predicted to be located in membrane. Expressed in AIML; AIMR; and in male. WB:WBGene00005634 srj-55 Predicted to be located in membrane. WB:WBGene00005635 srj-57 Predicted to be located in membrane. WB:WBGene00005636 srl-1 No description available WB:WBGene00005637 srl-2 No description available WB:WBGene00005638 srm-1 Predicted to be located in membrane. Expressed in ganglia and pharynx. WB:WBGene00005639 srm-2 Predicted to be located in membrane. Expressed in neurons. WB:WBGene00005640 srn-1 Predicted to be located in membrane. Expressed in amphid neurons and head neurons. WB:WBGene00005641 sro-1 Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to be located in membrane. Expressed in SIADL; SIADR; SIAVL; and SIAVR. Is an ortholog of human OPN4 (opsin 4). WB:WBGene00005642 srp-1 Predicted to enable peptidase activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in proteolysis. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in several diseases, including familial encephalopathy with neuroserpin inclusion bodies; intermediate coronary syndrome; and thrombophilia (multiple). Is an ortholog of several human genes including SERPINB1 (serpin family B member 1); SERPINB8 (serpin family B member 8); and SERPINC1 (serpin family C member 1). WB:WBGene00005643 srp-2 Enables cysteine-type endopeptidase inhibitor activity and serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular space. Expressed in several structures, including anal sphincter muscle; cuticle; epithelial cell; intestine; and phasmid neurons. Used to study familial encephalopathy with neuroserpin inclusion bodies. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Is an ortholog of human SERPINI1 (serpin family I member 1) and SERPINI2 (serpin family I member 2). WB:WBGene00005644 srp-3 Predicted to enable peptidase activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. Expressed in body wall musculature; intestine; and muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Is an ortholog of human SERPINI1 (serpin family I member 1) and SERPINI2 (serpin family I member 2). WB:WBGene00005646 srp-5 Enriched in body wall muscle cell and hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by Hydrolyzable Tannins; Humic Substances; and Sirolimus based on microarray studies. WB:WBGene00005647 srp-6 Predicted to enable peptidase activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. Expressed in hermaphrodite gonad; intestine; pharyngeal-intestinal valve; socket cell; and vulva. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autosomal recessive nonsyndromic deafness 91; and familial encephalopathy with neuroserpin inclusion bodies. Is an ortholog of several human genes including SERPINB1 (serpin family B member 1); SERPINB8 (serpin family B member 8); and SERPINB9 (serpin family B member 9). WB:WBGene00005648 srp-7 Predicted to enable peptidase activity and serine-type endopeptidase inhibitor activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autosomal recessive nonsyndromic deafness 91; and thrombophilia (multiple). Is an ortholog of several human genes including SERPINB1 (serpin family B member 1); SERPINB8 (serpin family B member 8); and SERPINC1 (serpin family C member 1). WB:WBGene00005649 srp-8 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including SERPINB1 (serpin family B member 1); SERPINB8 (serpin family B member 8); and SERPINB9 (serpin family B member 9). WB:WBGene00005650 srp-9 Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including aldicarb; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00005651 srp-10 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including aldicarb; methylmercuric chloride; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00005652 srr-1 Predicted to be located in membrane. Expressed in neuronal sheath cell; pharynx; and ray. WB:WBGene00005653 srr-2 Predicted to be located in membrane. Expressed in isthmus and terminal bulb. WB:WBGene00005654 srr-3 Predicted to be located in membrane. Expressed in several structures, including RMD; anal depressor muscle; head mesodermal cell; pharyngeal-intestinal valve; and phasmid neurons. WB:WBGene00005655 srr-4 Involved in determination of adult lifespan. Predicted to be located in membrane. Expressed in head neurons; hypodermis; pharynx; phasmid neurons; and vulva. WB:WBGene00005656 srr-5 Enriched in AFD based on RNA-seq studies. Is affected by several genes including elt-2; lin-15B; and rrf-1 based on microarray and RNA-seq studies. Is affected by tryptophan and cadmium based on microarray studies. WB:WBGene00005657 srr-6 Predicted to be located in membrane. Expressed in retrovesicular ganglion. WB:WBGene00005658 srr-7 Predicted to be located in membrane. Expressed in PVT; chemosensory neurons; and lateral ganglion. WB:WBGene00005659 srr-8 Predicted to be located in membrane. Expressed in ASIL; ASIR; PVT; excretory cell; and head neurons. WB:WBGene00005660 srr-9 Predicted to be located in membrane. Expressed in ASIL; ASIR; and neurons. WB:WBGene00005661 srr-10 Predicted to be located in membrane. Expressed in ganglia; head neurons; and rectal gland cell. WB:WBGene00005662 sars-2 Predicted to enable serine-tRNA ligase activity and tRNA binding activity. Predicted to be involved in mitochondrial seryl-tRNA aminoacylation. Predicted to be located in mitochondrion. Is an ortholog of human SARS2 (seryl-tRNA synthetase 2, mitochondrial). WB:WBGene00005663 sars-1 Predicted to enable serine-tRNA ligase activity and tRNA binding activity. Involved in translation. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in intellectual disability and prostate carcinoma. Is an ortholog of human SARS1 (seryl-tRNA synthetase 1). WB:WBGene00005664 sru-1 Predicted to be located in membrane. Expressed in ciliated neurons and pharynx. WB:WBGene00005665 sru-2 Predicted to be located in membrane. Expressed in PHAL; PHAR; PHBL; and PHBR. WB:WBGene00005666 sru-3 Predicted to be located in membrane. WB:WBGene00005667 sru-4 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005668 sru-5 Enriched in ASI and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hpl-2; dpy-21; and qui-1 based on RNA-seq studies. Is affected by Colistin based on microarray studies. WB:WBGene00005669 sru-6 Predicted to be located in membrane. WB:WBGene00005670 sru-7 Predicted to be located in membrane. WB:WBGene00005671 sru-8 Predicted to be located in membrane. Expressed in neurons and ventral ganglion. WB:WBGene00005672 sru-9 Enriched in anal depressor muscle and intestinal muscle based on single-cell RNA-seq studies. Is affected by several genes including clk-1; bar-1; and mdt-15 based on tiling array; microarray; and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class u (Sru) and Serpentine type 7TM GPCR chemoreceptor Sru. WB:WBGene00005673 sru-10 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00005674 sru-11 Predicted to be located in membrane. WB:WBGene00005675 sru-12 Predicted to be located in membrane. Expressed in OLL and chemosensory neurons. WB:WBGene00005676 sru-13 Enriched in neurons based on RNA-seq and microarray studies. Is affected by several genes including clk-1; prg-1; and alg-1 based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class u (Sru) and Serpentine type 7TM GPCR chemoreceptor Sru. WB:WBGene00005677 sru-14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00005678 sru-15 Predicted to be located in membrane. WB:WBGene00005679 sru-16 Predicted to be located in membrane. WB:WBGene00005680 sru-17 Predicted to be located in membrane. Expressed in neurons. WB:WBGene00005681 sru-18 Predicted to be located in membrane. WB:WBGene00005682 sru-19 Predicted to be located in membrane. WB:WBGene00005683 sru-20 Predicted to be located in membrane. WB:WBGene00005684 sru-21 Predicted to be located in membrane. WB:WBGene00005685 sru-22 Predicted to be located in membrane. WB:WBGene00005686 sru-23 Predicted to be located in membrane. WB:WBGene00005687 sru-24 Predicted to be located in membrane. WB:WBGene00005688 sru-25 Predicted to be located in membrane. WB:WBGene00005689 sru-26 Predicted to be located in membrane. WB:WBGene00005690 sru-27 Predicted to be located in membrane. Expressed in neurons. WB:WBGene00005691 sru-28 Predicted to be located in membrane. WB:WBGene00005692 sru-29 Predicted to be located in membrane. WB:WBGene00005693 sru-30 Predicted to be located in membrane. Expressed in chemosensory neurons. WB:WBGene00005694 sru-31 Predicted to be located in membrane. WB:WBGene00005695 sru-32 Enriched in sensory neurons based on RNA-seq studies. Is affected by dpy-21 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00005696 sru-33 Enriched in neurons based on RNA-seq studies. Is affected by rsr-2; etr-1; and qui-1 based on tiling array and RNA-seq studies. WB:WBGene00005697 sru-34 Enriched in AVK based on RNA-seq studies. Is affected by clk-1 based on microarray studies. WB:WBGene00005698 sru-35 Predicted to be located in membrane. WB:WBGene00005699 sru-36 Predicted to be located in membrane. WB:WBGene00005700 sru-37 Predicted to be located in membrane. WB:WBGene00005701 sru-38 Located in neuronal cell body and plasma membrane bounded cell projection. Expressed in ASHL; ASHR; AWBL; and AWBR. WB:WBGene00005702 sru-39 Predicted to be located in membrane. WB:WBGene00005703 sru-40 Predicted to be located in membrane. WB:WBGene00005704 sru-41 Is affected by cyc-1 and etr-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00005705 sru-42 Predicted to be located in membrane. WB:WBGene00005706 sru-43 Is affected by eat-2 and sir-2.1 based on RNA-seq and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00005707 sru-44 Predicted to be located in membrane. WB:WBGene00005708 sru-45 Predicted to be located in membrane. WB:WBGene00005709 sru-46 Enriched in muscle cell; neurons; and retrovesicular ganglion based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq and microarray studies. Is affected by allantoin and nitroguanidine based on microarray studies. WB:WBGene00005710 sru-47 Predicted to be located in membrane. WB:WBGene00005711 sru-48 Predicted to be located in membrane. Expressed in PVT; amphid neurons; and intestine. WB:WBGene00005712 srv-1 Predicted to be located in membrane. Expressed in CAN; amphid neurons; and excretory duct. WB:WBGene00005713 srv-2 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00005714 srv-3 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005715 srv-4 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00005716 srv-5 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in amphid neurons and sensory neurons. WB:WBGene00005717 srv-6 Predicted to be located in membrane. WB:WBGene00005718 srv-7 Predicted to be located in membrane. WB:WBGene00005719 srv-8 Predicted to be located in membrane. Expressed in ASKL; ASKR; PHCL; PHCR; and sensory neurons. WB:WBGene00005720 srv-9 Predicted to be located in membrane. WB:WBGene00005721 srv-10 Predicted to be located in membrane. WB:WBGene00005722 srv-11 Predicted to be located in membrane. Expressed in ASHL and ASHR. WB:WBGene00005723 srv-12 Predicted to be located in membrane. Expressed in ADLL; ADLR; ASJL; and ASJR. WB:WBGene00005724 srv-13 Predicted to be located in membrane. WB:WBGene00005725 srv-14 Predicted to be located in membrane. WB:WBGene00005726 srv-15 Predicted to be located in membrane. WB:WBGene00005727 srv-16 Predicted to be located in membrane. WB:WBGene00005728 srv-17 Predicted to be located in membrane. Expressed in ASIL; ASIR; and pharynx. WB:WBGene00005729 srv-18 Is affected by several genes including eat-2; clk-1; and cyc-1 based on microarray and RNA-seq studies. Is affected by Diazinon based on microarray studies. WB:WBGene00005730 srv-19 Predicted to be located in membrane. WB:WBGene00005731 srv-20 Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00005732 srv-21 Predicted to be located in membrane. Expressed in ASHL; ASHR; ASJL; ASJR; and neurons. WB:WBGene00005733 srv-22 Predicted to be located in membrane. WB:WBGene00005734 srv-23 Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00005735 srv-24 Predicted to be located in membrane. WB:WBGene00005736 srv-25 Predicted to be located in membrane. WB:WBGene00005737 srv-26 Predicted to be located in membrane. WB:WBGene00005738 srv-27 Predicted to be located in membrane. Expressed in nerve ring neurons and sensory neurons. WB:WBGene00005739 srv-28 Predicted to be located in membrane. WB:WBGene00005740 srv-29 Predicted to be located in membrane. WB:WBGene00005741 srv-30 Predicted to be located in membrane. WB:WBGene00005742 srv-31 Predicted to be located in membrane. WB:WBGene00005743 srv-32 Predicted to be located in membrane. Expressed in PVQ and head ganglion. WB:WBGene00005744 ops-1 Predicted to be located in membrane. Expressed in ADLL; ADLR; ASGL; and ASGR. WB:WBGene00005745 srv-34 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in ASKL; ASKR; AWAL; AWAR; and retrovesicular ganglion. WB:WBGene00005746 srv-35 Is affected by cyc-1 and rrf-1 based on microarray studies. Is affected by Diazinon based on microarray studies. WB:WBGene00005747 srv-36 Enriched in OLL; PVD; cephalic sheath cell; dopaminergic neurons; and hypodermis based on tiling array studies. Is affected by several genes including eat-2; sir-2.1; and hpl-2 based on microarray and RNA-seq studies. Is affected by resveratrol; adsorbable organic bromine compound; and allantoin based on microarray studies. WB:WBGene00005748 srw-1 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005749 srw-2 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005750 srw-3 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005751 srw-4 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005752 srw-5 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00005753 srw-6 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005754 srw-7 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005755 srw-8 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005756 srw-9 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005757 srw-10 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005758 srw-11 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005759 srw-12 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005760 srw-13 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005761 srw-14 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005762 srw-15 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005763 srw-16 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005764 srw-17 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005765 srw-18 Is affected by sir-2.1 based on microarray studies. WB:WBGene00005766 srw-19 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005767 srw-20 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005768 srw-21 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005769 srw-22 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005770 srw-23 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005771 srw-24 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005772 srw-25 Is affected by several genes including mrps-5; etr-1; and his-3 based on RNA-seq studies. Is affected by nitroguanidine based on microarray studies. WB:WBGene00005773 srw-26 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005774 srw-27 Is affected by ain-1 and let-60 based on microarray studies. WB:WBGene00005775 srw-28 No description available WB:WBGene00005776 srw-29 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in neuronal sheath cell. WB:WBGene00005777 srw-30 Is affected by several genes including cyd-1; cdk-4; and rsr-2 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00005778 srw-31 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005779 srw-32 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005780 srw-33 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005781 srw-34 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005782 srw-35 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005783 srw-36 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005784 srw-37 Enriched in muscle cell and neurons based on microarray studies. Is affected by rsr-2 and qui-1 based on tiling array and RNA-seq studies. Is affected by dibromoacetic acid; Microcystin-LR; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00005785 srw-38 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005786 srw-39 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005787 srw-40 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005788 srw-41 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005789 srw-42 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005790 srw-43 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005791 srw-44 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005792 srw-45 Is affected by clk-1 based on microarray studies. WB:WBGene00005793 srw-46 Is affected by several genes including clk-1; pgl-1; and glh-1 based on microarray and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00005794 srw-47 Is affected by several genes including sir-2.1; mdt-15; and drh-3 based on tiling array; microarray; and RNA-seq studies. Is affected by dibromoacetic acid based on microarray studies. WB:WBGene00005795 srw-48 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005796 srw-49 No description available WB:WBGene00005797 srw-50 Is affected by resveratrol based on microarray studies. WB:WBGene00005798 srw-51 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005799 srw-52 Is affected by dafa#1 and adsorbable organic bromine compound based on microarray studies. WB:WBGene00005800 srw-53 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005801 srw-54 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005802 srw-55 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005803 srw-56 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005804 srw-57 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005805 srw-58 Is affected by several genes including sir-2.1; prg-1; and ain-1 based on tiling array and microarray studies. Is affected by aldicarb based on microarray studies. WB:WBGene00005806 srw-59 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005807 srw-60 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005808 srw-61 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005809 srw-62 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005810 srw-63 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005811 srw-64 Is affected by several genes including eat-2; nhr-25; and dpy-21 based on microarray and RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00005812 srw-65 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; hpl-2; and rsr-2 based on tiling array and RNA-seq studies. WB:WBGene00005813 srw-66 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005814 srw-67 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005815 srw-68 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005816 srw-69 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005817 srw-70 Is affected by several genes including daf-16; sir-2.1; and mdt-15 based on microarray and tiling array studies. Is affected by resveratrol; tetrabromobisphenol A; and dafa#1 based on microarray studies. WB:WBGene00005818 srw-71 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005819 srw-72 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005820 srw-73 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005821 srw-74 No description available WB:WBGene00005822 srw-75 Is affected by rsr-2 and mir-34 based on tiling array and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00005823 srw-76 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005824 srw-77 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005825 srw-78 Enriched in AVK and head mesodermal cell based on RNA-seq studies. Is affected by several genes including pgl-1; unc-30; and glh-1 based on RNA-seq and microarray studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00005826 srw-79 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005827 srw-80 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including let-418; adr-1; and etr-1 based on RNA-seq studies. WB:WBGene00005828 srw-81 No description available WB:WBGene00005829 srw-82 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005830 srw-83 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005831 srw-84 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005832 srw-85 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in neurons. WB:WBGene00005833 srw-86 Enriched in XXX cell; dopaminergic neurons; head mesodermal cell; intestine; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Ethanol; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00005834 srw-87 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005835 srw-88 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005836 srw-89 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005837 srw-90 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005838 srw-91 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005839 srw-92 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00005840 srw-93 Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00005841 srw-94 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005842 srw-95 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005843 srw-96 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including tryptophan; Rifampin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00005844 srw-97 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005845 srw-98 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005846 srw-99 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005847 srw-100 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005848 srw-101 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005849 srw-102 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005850 srw-103 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in amphid neurons; head neurons; and nervous system. WB:WBGene00005851 srw-104 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol and dafa#1 based on microarray studies. WB:WBGene00005852 srw-105 Is affected by cyc-1 and sir-2.1 based on microarray studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00005853 srw-106 Is affected by several genes including sir-2.1; clk-1; and isp-1 based on microarray studies. Is affected by four chemicals including cadmium; Ethanol; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00005854 srw-107 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005855 srw-108 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in ASKL; ASKR; and anterior hypodermis. WB:WBGene00005856 srw-109 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005857 srw-110 No description available WB:WBGene00005858 srw-111 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005859 srw-112 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005860 srw-113 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005861 srw-114 Is affected by several genes including lin-4; lin-14; and sir-2.1 based on microarray studies. Is affected by adsorbable organic bromine compound and allantoin based on microarray studies. WB:WBGene00005862 srw-115 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005863 srw-116 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00005864 srw-117 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005865 srw-118 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005866 srw-119 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in ASGL and ASGR. WB:WBGene00005867 srw-120 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005868 srw-121 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005869 srw-122 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005870 srw-123 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005871 srw-124 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005872 srw-125 Is affected by etr-1 based on RNA-seq studies. Is affected by allantoin based on microarray studies. WB:WBGene00005873 srw-126 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray studies. WB:WBGene00005874 srw-127 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005875 srw-128 No description available WB:WBGene00005876 srw-129 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005877 srw-130 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005878 srw-131 Is affected by clk-1; etr-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by adsorbable organic bromine compound and allantoin based on microarray studies. WB:WBGene00005879 srw-132 Is affected by several genes including let-60; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by aldicarb based on microarray studies. WB:WBGene00005880 srw-133 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005881 srw-134 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005882 srw-135 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005883 srw-136 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005884 srw-137 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005885 srw-138 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in ADLL and ADLR. WB:WBGene00005886 srw-139 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in neurons. WB:WBGene00005887 srw-140 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005888 srw-141 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005889 srw-142 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005890 srw-143 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005891 srw-144 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00005892 srx-1 Predicted to be located in membrane. Expressed in head mesodermal cell; neurons; and non-striated muscle. WB:WBGene00005893 srx-2 Predicted to be located in membrane. WB:WBGene00005894 srx-3 Predicted to be located in membrane. Expressed in motor neurons and nerve ring neurons. WB:WBGene00005895 srx-4 Predicted to be located in membrane. Expressed in amphid neurons; rectal epithelial cell; and vulval cell. WB:WBGene00005896 srx-5 Predicted to be located in membrane. WB:WBGene00005897 srx-6 Predicted to be located in membrane. WB:WBGene00005898 srx-7 Predicted to be located in membrane. WB:WBGene00005899 srx-8 Predicted to be located in membrane. WB:WBGene00005900 srx-9 Predicted to be located in membrane. WB:WBGene00005901 srx-10 Predicted to be located in membrane. Expressed in ASIL; ASIR; PVT; intestine; and pharynx. WB:WBGene00005902 srx-11 Enriched in RID based on RNA-seq studies. Is affected by cyc-1; hpl-2; and wdr-5.1 based on microarray and RNA-seq studies. Is affected by stavudine and Colistin based on RNA-seq and microarray studies. WB:WBGene00005903 srx-12 Predicted to be located in membrane. Expressed in ADFL; ADFR; and amphid sheath cell. WB:WBGene00005904 srx-13 Predicted to be located in membrane. WB:WBGene00005905 srx-14 Predicted to be located in membrane. Expressed in chemosensory neurons and head neurons. WB:WBGene00005906 srx-15 Enriched in AWA based on single-cell RNA-seq studies. Is affected by several genes including clk-1; bcat-1; and etr-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00005907 srx-16 Predicted to be located in membrane. WB:WBGene00005908 srx-17 Predicted to be located in membrane. Expressed in ASIL; ASIR; PVT; and ventral ganglion. WB:WBGene00005909 srx-18 Predicted to be located in membrane. WB:WBGene00005910 srx-19 Predicted to be located in membrane. WB:WBGene00005911 srx-20 Predicted to be located in membrane. WB:WBGene00005912 srx-21 Predicted to be located in membrane. WB:WBGene00005913 srx-22 Predicted to be located in membrane. Expressed in ASIL; ASIR; I2L; I2R; and neurons. WB:WBGene00005914 srx-23 Predicted to be located in membrane. WB:WBGene00005915 srx-24 Predicted to be located in membrane. WB:WBGene00005916 srx-25 Is affected by mdt-15 and nhr-25 based on microarray studies. WB:WBGene00005917 srx-26 Predicted to be located in membrane. WB:WBGene00005918 srx-27 Is affected by daf-2 and eat-2 based on microarray studies. Is affected by allantoin and Sirolimus based on microarray studies. WB:WBGene00005919 srx-28 Predicted to be located in membrane. WB:WBGene00005920 srx-29 Predicted to be located in membrane. WB:WBGene00005921 srx-30 Is affected by cyc-1; clk-1; and eat-2 based on microarray studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00005922 srx-31 Predicted to be located in membrane. WB:WBGene00005923 srx-32 Predicted to be located in membrane. WB:WBGene00005924 srx-33 Predicted to be located in membrane. WB:WBGene00005925 srx-34 Predicted to be located in membrane. WB:WBGene00005926 srx-35 Is affected by several genes including eat-2; mex-1; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00005927 srx-36 Predicted to be located in membrane. WB:WBGene00005928 srx-37 No description available WB:WBGene00005929 srx-38 Predicted to be located in membrane. WB:WBGene00005930 srx-39 Predicted to be located in membrane. WB:WBGene00005931 fbxa-199 Predicted to be located in membrane. WB:WBGene00005932 srx-41 Predicted to be located in membrane. Expressed in dorsal nerve cord; head muscle; head neurons; and tail neurons. WB:WBGene00005933 srx-42 Predicted to be located in membrane. WB:WBGene00005934 srx-43 Enables pheromone receptor activity. Involved in calcium-mediated signaling; cellular response to pheromone; and locomotory exploration behavior. Located in non-motile cilium and perikaryon. Expressed in ASIL and ASIR. WB:WBGene00005935 srx-44 Predicted to be located in membrane. Expressed in ADLL; ADLR; ASJL; and ASJR. WB:WBGene00005936 srx-45 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in linker cell. WB:WBGene00005937 srx-46 Predicted to be located in membrane. WB:WBGene00005938 srx-47 Predicted to be located in membrane. Expressed in intestine; odorsensory neurons; and tail. WB:WBGene00005939 srx-48 Predicted to be located in membrane. WB:WBGene00005940 srx-49 Is affected by rsr-2 and spt-16 based on tiling array and RNA-seq studies. Is affected by Mercuric Chloride and adsorbable organic bromine compound based on microarray studies. WB:WBGene00005941 srx-50 Predicted to be located in membrane. WB:WBGene00005942 srx-51 Predicted to be located in membrane. WB:WBGene00005943 srx-52 Is affected by clk-1 and sir-2.1 based on microarray studies. WB:WBGene00005944 srx-53 Is affected by several genes including hpl-2; cyc-1; and mir-34 based on microarray and tiling array studies. Is affected by five chemicals including resveratrol; dibromoacetic acid; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00005945 srx-54 Predicted to be located in membrane. WB:WBGene00005946 srx-55 Is affected by eat-2 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00005947 srx-56 Predicted to be located in membrane. WB:WBGene00005948 srx-57 Is affected by sir-2.1 based on microarray studies. WB:WBGene00005949 srx-58 Predicted to be located in membrane. WB:WBGene00005950 srx-59 Predicted to be located in membrane. WB:WBGene00005951 srx-60 Predicted to be located in membrane. WB:WBGene00005952 srx-61 Is affected by cyc-1 and adr-1 based on microarray and RNA-seq studies. WB:WBGene00005953 srx-62 Predicted to be located in membrane. WB:WBGene00005954 srx-63 Predicted to be located in membrane. WB:WBGene00005955 srx-64 Predicted to be located in membrane. WB:WBGene00005956 srx-65 Predicted to be located in membrane. WB:WBGene00005957 srx-66 Predicted to be located in membrane. WB:WBGene00005958 srx-67 Predicted to be located in membrane. WB:WBGene00005959 srx-68 Predicted to be located in membrane. WB:WBGene00005960 srx-69 Is affected by rrf-1 based on microarray studies. Is affected by single-walled carbon nanotube based on microarray studies. WB:WBGene00005961 srx-70 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00005962 srx-71 Is affected by clk-1 based on microarray studies. Is affected by resveratrol and allantoin based on microarray studies. WB:WBGene00005963 srx-72 Is affected by several genes including clk-1; let-418; and adr-1 based on microarray and RNA-seq studies. WB:WBGene00005964 srx-73 Predicted to be located in membrane. WB:WBGene00005965 srx-74 Enriched in anterior ganglion and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including clk-1; csr-1; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class x (Srx) and Serpentine type 7TM GPCR chemoreceptor Srx. WB:WBGene00005966 srx-75 Enriched in body wall musculature based on microarray studies. Is affected by several genes including sir-2.1; cyc-1; and ain-2 based on microarray and RNA-seq studies. WB:WBGene00005967 srx-76 Predicted to be located in membrane. Expressed in neurons and in male. WB:WBGene00005968 srx-77 Predicted to be located in membrane. WB:WBGene00005969 srx-78 Predicted to be located in membrane. WB:WBGene00005970 srx-79 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including rrf-1; mir-34; and etr-1 based on RNA-seq and microarray studies. Is affected by resveratrol; Diazinon; and copper sulfate based on microarray studies. WB:WBGene00005971 srx-80 Predicted to be located in membrane. WB:WBGene00005972 srx-81 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00005973 srx-82 Predicted to be located in membrane. WB:WBGene00005974 srx-83 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00005975 srx-84 Predicted to be located in membrane. WB:WBGene00005976 srx-85 Predicted to be located in membrane. WB:WBGene00005977 srx-86 Predicted to be located in membrane. WB:WBGene00005978 srx-87 Predicted to be located in membrane. WB:WBGene00005979 srx-88 Predicted to be located in membrane. WB:WBGene00005980 srx-89 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; alg-1; and glh-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Ag nanoparticles based on RNA-seq studies. WB:WBGene00005981 srx-90 Predicted to be located in membrane. WB:WBGene00005982 srx-91 Is affected by several genes including lin-4; eat-2; and lin-14 based on microarray and RNA-seq studies. WB:WBGene00005983 srx-92 Predicted to be located in membrane. WB:WBGene00005984 srx-93 Predicted to be located in membrane. WB:WBGene00005985 srx-94 Is affected by sir-2.1 based on microarray studies. Is affected by nitroguanidine based on microarray studies. WB:WBGene00005986 srx-95 Predicted to be located in membrane. WB:WBGene00005987 srx-96 Predicted to be located in membrane. WB:WBGene00005988 srx-97 Predicted to enable G protein-coupled olfactory receptor activity. Involved in olfactory behavior. Located in non-motile cilium. Expressed in ASHL; ASHR; PHBL; and PHBR. WB:WBGene00005989 srx-98 Predicted to be located in membrane. WB:WBGene00005990 srx-99 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00005991 srx-100 No description available WB:WBGene00005992 srx-101 Predicted to be located in membrane. WB:WBGene00005993 srx-102 Predicted to be located in membrane. WB:WBGene00005994 srx-103 Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00005995 srx-104 Predicted to be located in membrane. WB:WBGene00005996 srx-105 Predicted to be located in membrane. Expressed in chemosensory neurons. WB:WBGene00005997 srx-106 Is affected by cyc-1 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00005998 srx-107 Enriched in FLP based on microarray studies. Is affected by several genes including clk-1; dpy-21; and tdp-1 based on microarray and RNA-seq studies. Is affected by resveratrol and dafa#1 based on microarray studies. WB:WBGene00005999 srx-108 Predicted to be located in membrane. WB:WBGene00006000 srx-109 Is affected by clk-1; etr-1; and eri-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00006001 srx-110 Predicted to be located in membrane. Expressed in PHBL and PHBR. WB:WBGene00006002 srx-111 Predicted to be located in membrane. WB:WBGene00006003 srx-112 Predicted to be located in membrane. WB:WBGene00006004 srx-113 Predicted to be located in membrane. Expressed in FLP and tail neurons. WB:WBGene00006005 srx-114 Predicted to be located in membrane. WB:WBGene00006006 srx-115 Predicted to be located in membrane. WB:WBGene00006007 srx-116 Predicted to be located in membrane. WB:WBGene00006008 srx-117 Predicted to be located in membrane. WB:WBGene00006009 srx-118 Predicted to be located in membrane. WB:WBGene00006010 srx-119 Predicted to be located in membrane. WB:WBGene00006011 srx-120 Predicted to be located in membrane. WB:WBGene00006012 srx-121 Predicted to be located in membrane. WB:WBGene00006013 srx-122 Predicted to be located in membrane. WB:WBGene00006014 srx-123 Enriched in AUA and FLP based on microarray and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and cyc-1 based on microarray and RNA-seq studies. WB:WBGene00006015 srx-124 Enriched in AUA based on single-cell RNA-seq studies. Is affected by lpd-3 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00006016 srx-125 Predicted to be located in membrane. WB:WBGene00006017 srx-126 Enriched in sensory neurons based on RNA-seq studies. Is affected by clk-1 and sir-2.1 based on microarray studies. Is affected by dafa#1 and allantoin based on microarray studies. WB:WBGene00006018 srx-127 Is affected by sir-2.1 based on microarray studies. WB:WBGene00006019 srx-128 Predicted to be located in membrane. WB:WBGene00006020 srx-129 Predicted to be located in membrane. WB:WBGene00006021 srx-130 Predicted to be located in membrane. WB:WBGene00006022 srx-131 Predicted to be located in membrane. WB:WBGene00006023 srx-132 Is affected by clk-1 and sir-2.1 based on microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00006024 srx-133 Predicted to be located in membrane. WB:WBGene00006025 srx-134 Predicted to be located in membrane. WB:WBGene00006026 srx-135 Predicted to be located in membrane. WB:WBGene00006027 srx-136 Predicted to be located in membrane. WB:WBGene00006028 srx-137 Predicted to be located in membrane. WB:WBGene00006029 srx-138 Is affected by cyc-1 and sir-2.1 based on microarray studies. WB:WBGene00006038 ssp-9 Enriched in several structures, including ALM; BDU; amphid sheath cell; germ line; and sperm based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; methylmercuric chloride; and D-glucose based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; Immunoglobulin-like fold; MSP (Major sperm protein) domain; and Phosphorylation site. WB:WBGene00006039 ssp-10 Enriched in amphid sheath cell; germ line; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on RNA-seq; microarray; and proteomic studies. Is affected by twenty-seven chemicals including hydrogen sulfide; Ethanol; and methylmercury hydroxide based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; Immunoglobulin-like fold; MSP (Major sperm protein) domain; and Phosphorylation site. WB:WBGene00006040 ssp-11 Enriched in sperm and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including Ethanol; methylmercuric chloride; and D-glucose based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; Immunoglobulin-like fold; MSP (Major sperm protein) domain; and Phosphorylation site. WB:WBGene00006044 ssp-16 Expressed in male gonad. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; Immunoglobulin-like fold; MSP (Major sperm protein) domain; and Phosphorylation site. WB:WBGene00006047 ssp-19 Enables protein homodimerization activity. Expressed in spermatheca. WB:WBGene00006048 ssp-31 Enriched in AFD; amphid sheath cell; intestine; sperm; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00006049 ssp-32 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; antimycin; and cholesterol based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00006050 ssq-1 Enriched in several structures, including amphid sheath cell; distal tip cell; germ line; neurons; and sperm based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-six chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq; microarray; and proteomic studies. WB:WBGene00006051 ssq-2 Enriched in several structures, including ALN; BDU; distal tip cell; sperm; and touch receptor neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-eight chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq; microarray; and proteomic studies. WB:WBGene00006052 ssq-3 Enriched in ABarppaapp; ABarpppapp; intestine; and sperm based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by thirty chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00006053 ssq-4 Enriched in amphid sheath cell and sperm based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-eight chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq; microarray; and proteomic studies. WB:WBGene00006054 ssr-1 No description available WB:WBGene00006055 ssr-2 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be located in plasma membrane. Is an ortholog of human RASD2 (RASD family member 2). WB:WBGene00006056 sss-1 Enriched in several structures, including ABalaaaarl; ABalaaaarr; amphid sheath cell; germ line; and sperm based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by thirty-one chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00006057 sss-2 Enriched in germ line; intestine; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray and RNA-seq studies. Is affected by thirty-one chemicals including hydrogen sulfide; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00006058 sst-20 Predicted to be located in membrane. WB:WBGene00006059 stc-1 Predicted to enable ATP binding activity and ATP-dependent protein folding chaperone. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum. Is an ortholog of human HSPA13 (heat shock protein family A (Hsp70) member 13). WB:WBGene00006060 sth-1 Located in plasma membrane. Expressed in germ line and spermatheca. WB:WBGene00006061 stl-1 Predicted to be involved in mitochondrion organization. Located in mitochondrion. Expressed in head neurons and pharynx. Is an ortholog of human STOML2 (stomatin like 2). WB:WBGene00006062 stn-1 Enables acetylcholine transmembrane transporter activity and calcium channel regulator activity. Involved in several processes, including muscle cell cellular homeostasis; regulation of locomotion; and sarcomere organization. Part of dystrophin-associated glycoprotein complex. Expressed in body wall musculature; neurons; and vulval muscle. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in long QT syndrome 12 and sudden infant death syndrome. Is an ortholog of human SNTB2 (syntrophin beta 2). WB:WBGene00006063 sto-1 Predicted to be located in plasma membrane. WB:WBGene00006064 sto-2 Predicted to be located in plasma membrane. Is an ortholog of human STOM (stomatin). WB:WBGene00006065 sto-3 Predicted to be located in plasma membrane. Expressed in RIB; ray neuron type B; and tail. WB:WBGene00006066 sto-4 Predicted to be located in plasma membrane. Expressed in neurons. WB:WBGene00006067 sto-5 Predicted to be located in plasma membrane. Expressed in FLPL and FLPR. WB:WBGene00006068 sto-6 Predicted to be located in plasma membrane. WB:WBGene00006069 str-1 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Located in non-motile cilium. WB:WBGene00006070 str-2 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Located in non-motile cilium. Expressed in ASIL; ASIR; AWC-ON; AWCL; and AWCR. WB:WBGene00006071 str-3 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in plasma membrane. Expressed in ASIL and ASIR. WB:WBGene00006072 str-4 Predicted to be located in membrane. WB:WBGene00006073 str-5 Predicted to be located in membrane. WB:WBGene00006074 str-6 Predicted to be located in membrane. WB:WBGene00006075 str-7 Predicted to be located in membrane. WB:WBGene00006076 str-8 Predicted to be located in membrane. WB:WBGene00006077 str-9 Predicted to be located in membrane. WB:WBGene00006078 str-10 Predicted to be located in membrane. WB:WBGene00006079 str-11 No description available WB:WBGene00006080 str-12 Predicted to be located in membrane. WB:WBGene00006081 str-13 Predicted to be located in membrane. WB:WBGene00006082 str-14 Predicted to be located in membrane. WB:WBGene00006083 str-15 Predicted to be located in membrane. WB:WBGene00006084 str-16 Predicted to be located in membrane. WB:WBGene00006085 str-18 Predicted to be located in membrane. WB:WBGene00006086 str-19 Predicted to be located in membrane. WB:WBGene00006087 str-20 Predicted to be located in membrane. WB:WBGene00006088 str-21 No description available WB:WBGene00006089 str-22 Is affected by clk-1 and eat-2 based on microarray studies. WB:WBGene00006090 str-23 Predicted to be located in membrane. WB:WBGene00006091 str-24 Is affected by 2 and 4-dinitroanisole based on microarray studies. WB:WBGene00006092 str-25 Predicted to be located in membrane. WB:WBGene00006093 str-27 Predicted to be located in membrane. WB:WBGene00006094 str-28 Predicted to be located in membrane. WB:WBGene00006095 str-29 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00006096 str-30 Predicted to be located in membrane. WB:WBGene00006097 str-31 Predicted to be located in membrane. Expressed in PVT; hypodermis; rectal epithelial cell; and vulva. WB:WBGene00006098 str-32 Predicted to be located in membrane. WB:WBGene00006099 str-33 Predicted to be located in membrane. Expressed in ALML; ALMR; PLML; PLMR; and head neurons. WB:WBGene00006100 str-34 No description available WB:WBGene00006101 str-35 Is affected by clk-1 and sir-2.1 based on microarray studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class r (Str) and Serpentine type 7TM GPCR chemoreceptor Str. WB:WBGene00006102 str-37 Predicted to be located in membrane. WB:WBGene00006103 str-38 Predicted to be located in membrane. WB:WBGene00006104 str-39 Predicted to be located in membrane. WB:WBGene00006105 str-40 Predicted to be located in membrane. WB:WBGene00006106 str-41 Predicted to be located in membrane. WB:WBGene00006107 str-42 No description available WB:WBGene00006108 str-43 Predicted to be located in membrane. WB:WBGene00006109 str-44 Located in non-motile cilium. Expressed in AWAL; AWAR; AWBL; AWBR; and in male. WB:WBGene00006110 str-45 Predicted to be located in membrane. WB:WBGene00006111 str-46 Predicted to be located in membrane. WB:WBGene00006112 str-47 Predicted to be located in membrane. WB:WBGene00006113 str-48 Predicted to be located in membrane. WB:WBGene00006114 str-49 Is affected by several genes including sir-2.1; etr-1; and hlh-26 based on RNA-seq and microarray studies. WB:WBGene00006115 str-50 No description available WB:WBGene00006116 str-51 Is affected by clk-1 and sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00006117 str-52 Predicted to be located in membrane. Expressed in chemosensory neurons; head; pharynx; tail hypodermis; and tail neurons. WB:WBGene00006118 str-53 Is affected by wdr-23 and let-60 based on RNA-seq and microarray studies. WB:WBGene00006119 str-54 No description available WB:WBGene00006120 str-55 Predicted to be located in membrane. WB:WBGene00006121 str-56 Predicted to be located in membrane. WB:WBGene00006122 str-57 Predicted to be located in membrane. WB:WBGene00006123 str-58 Is affected by lin-14 and lin-4 based on microarray studies. WB:WBGene00006124 str-60 Predicted to be located in membrane. WB:WBGene00006125 str-61 Predicted to be located in membrane. WB:WBGene00006126 str-63 Predicted to be located in membrane. WB:WBGene00006127 str-64 Predicted to be located in membrane. WB:WBGene00006128 str-66 Predicted to be located in membrane. WB:WBGene00006129 str-67 Predicted to be located in membrane. WB:WBGene00006130 str-68 Predicted to be located in membrane. WB:WBGene00006131 str-69 Predicted to be located in membrane. WB:WBGene00006132 str-70 Is affected by resveratrol based on microarray studies. WB:WBGene00006133 str-71 Predicted to be located in membrane. WB:WBGene00006134 str-73 Predicted to be located in membrane. WB:WBGene00006135 str-74 Predicted to be located in membrane. Expressed in amphid neurons and head neurons. WB:WBGene00006136 str-76 Predicted to be located in membrane. WB:WBGene00006137 str-77 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006138 str-78 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006139 str-79 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006140 str-81 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006141 str-82 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006142 str-83 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006143 str-84 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in PVQ; chemosensory neurons; and retrovesicular ganglion. WB:WBGene00006144 str-85 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in head neurons and pharynx. WB:WBGene00006145 str-86 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006146 str-87 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006147 str-88 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006148 str-89 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006149 str-90 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in neurons. WB:WBGene00006150 str-92 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006151 str-93 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006152 str-94 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006153 str-96 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006154 str-97 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in ASIL; ASIR; and M1 neuron. WB:WBGene00006155 str-99 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006156 str-101 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006157 str-102 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in anal depressor muscle and head neurons. WB:WBGene00006158 str-103 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006159 str-106 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006160 str-108 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006161 str-109 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006162 str-111 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006163 str-112 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006164 str-113 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006165 str-114 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in chemosensory neurons; head muscle; and vulval muscle. WB:WBGene00006166 str-115 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006167 str-116 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in AWAL; AWAR; and in male. WB:WBGene00006168 str-117 Is affected by Ketamine based on RNA-seq studies. WB:WBGene00006169 str-118 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006170 str-119 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006171 str-120 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006172 str-121 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in head neurons and pharynx. WB:WBGene00006173 str-122 Is affected by several genes including sir-2.1; pgl-1; and mex-1 based on tiling array; RNA-seq; and microarray studies. Is affected by fluoranthene and adsorbable organic bromine compound based on microarray studies. WB:WBGene00006174 str-123 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in ASIL; ASIR; neurons; pharyngeal neurons; and pharynx. WB:WBGene00006175 str-124 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006176 str-125 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in head neurons and interneuron. WB:WBGene00006177 str-128 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. WB:WBGene00006178 str-129 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in head neurons. WB:WBGene00006179 str-130 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in AWC-OFF and neurons. WB:WBGene00006180 str-131 Predicted to enable G protein-coupled olfactory receptor activity. Involved in short-term memory. Predicted to be located in membrane. WB:WBGene00006181 str-133 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00006182 str-134 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006183 str-135 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006184 str-136 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006185 str-137 Is affected by let-60 based on microarray studies. WB:WBGene00006186 str-139 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006187 str-138 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006188 str-140 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006189 str-141 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006190 str-143 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in PVT; excretory system; head neurons; intestine; and pharynx. WB:WBGene00006191 str-144 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006192 str-145 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006193 str-146 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006194 str-147 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00006195 str-148 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in excretory duct cell; excretory pore; and seam cell. WB:WBGene00006196 str-149 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006197 str-150 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006198 str-151 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006199 str-153 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006200 str-154 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006201 str-155 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006202 str-156 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006203 str-158 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006204 str-159 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006205 str-160 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006206 str-161 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006207 str-162 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006208 str-163 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Located in non-motile cilium. Expressed in AWBL and AWBR. WB:WBGene00006209 str-164 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in AWAL; AWAR; and in male. WB:WBGene00006210 str-165 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006211 str-166 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006212 str-168 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006213 str-169 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006214 str-170 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006215 str-171 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006216 str-172 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006217 str-173 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006218 str-174 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006219 str-175 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006220 str-176 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in acute kidney failure and rheumatoid arthritis. Is an ortholog of several human genes including SLC22A14 (solute carrier family 22 member 14); SLC22A2 (solute carrier family 22 member 2); and SLC22A4 (solute carrier family 22 member 4). WB:WBGene00006221 str-177 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006222 str-178 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in ADLL; ADLR; and PVT. WB:WBGene00006223 str-179 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. Is affected by metformin and Psoralens based on RNA-seq studies. WB:WBGene00006224 str-180 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006225 str-181 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006226 str-182 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006227 str-183 Enriched in sensory neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00006228 str-185 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006229 str-187 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006230 str-188 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006231 str-190 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006232 str-193 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006233 str-196 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006234 str-198 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006235 str-199 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in AWCL; AWCR; and nervous system. WB:WBGene00006236 str-200 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006237 str-204 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006238 str-205 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006239 str-206 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006240 str-207 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006241 str-208 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006242 str-209 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006243 str-210 No description available WB:WBGene00006244 str-211 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006245 str-212 No description available WB:WBGene00006246 str-213 Is affected by sir-2.1 based on microarray studies. WB:WBGene00006247 str-214 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006248 str-216 Is affected by several genes including daf-2; eat-2; and smg-2 based on RNA-seq and microarray studies. WB:WBGene00006249 str-217 Predicted to enable G protein-coupled olfactory receptor activity. Involved in response to insecticide. Predicted to be located in plasma membrane. Expressed in ADLL and ADLR. WB:WBGene00006250 str-219 Is affected by resveratrol based on microarray studies. WB:WBGene00006251 str-220 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in AWBL and AWBR. WB:WBGene00006252 str-221 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006253 str-222 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006254 str-223 Is affected by hpl-2; sftb-1; and eri-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00006255 str-224 Enriched in MSpaaaaa; g1AL; g1AR; and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Chlorpyrifos; Diazinon; and allantoin based on microarray studies. WB:WBGene00006256 str-225 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006257 str-226 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006258 str-227 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006259 str-228 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006260 str-229 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006261 str-230 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006262 str-231 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in ASIL and ASIR. WB:WBGene00006263 str-232 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006264 str-233 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in BAGL; BAGR; head; head neurons; and rectal epithelial cell. WB:WBGene00006265 str-236 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in several structures, including ASI; PVT; intestine; pharynx; and ventral ganglion. WB:WBGene00006266 str-238 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006267 str-239 No description available WB:WBGene00006268 str-240 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006269 str-242 No description available WB:WBGene00006270 str-243 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006271 str-244 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006272 str-245 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006273 str-246 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006274 str-247 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in several structures, including ASI; PVT; head; intestine; and vulval muscle. WB:WBGene00006275 str-248 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006276 str-249 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in PVT and head neurons. WB:WBGene00006277 str-250 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in several structures, including ASI; pharynx; rectal epithelium; somatic nervous system; and tail hypodermis. WB:WBGene00006278 str-252 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006279 str-253 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in head neurons. WB:WBGene00006280 str-254 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006281 str-255 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006282 str-256 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006283 str-257 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006284 str-258 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006285 str-259 Is affected by smg-2; camt-1; and etr-1 based on RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00006286 str-260 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in AWAL; AWAR; and in male. WB:WBGene00006287 str-261 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in ASKL; ASKR; AWAL; and AWAR. WB:WBGene00006288 str-262 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in head neurons and vulval muscle. WB:WBGene00006289 str-263 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00006290 stu-2 No description available WB:WBGene00006291 stu-3 No description available WB:WBGene00006292 stu-6 No description available WB:WBGene00006293 stu-8 Acts upstream of or within embryo development; mitotic cell cycle; and vulval development. WB:WBGene00006294 stu-9 Acts upstream of or within embryo development and mitotic cell cycle. WB:WBGene00006295 stu-10 Acts upstream of or within embryo development and establishment of mitotic spindle orientation. WB:WBGene00006296 stu-11 Acts upstream of or within embryo development and establishment of mitotic spindle orientation. WB:WBGene00006297 stu-12 Acts upstream of or within embryo development and mitotic cell cycle. WB:WBGene00006298 stu-13 Acts upstream of or within embryo development and mitotic cell cycle. WB:WBGene00006299 stu-14 Acts upstream of or within embryo development and mitotic cell cycle. WB:WBGene00006300 stu-15 Acts upstream of or within embryo development and mitotic cell cycle. WB:WBGene00006301 stu-16 Acts upstream of or within embryo development; mitotic cell cycle; and vulval development. WB:WBGene00006302 stu-17 Acts upstream of or within embryo development; mitotic cell cycle; and vulval development. WB:WBGene00006304 stu-19 Acts upstream of or within embryo development and mitotic cell cycle. WB:WBGene00006305 sud-1 No description available WB:WBGene00006306 sue-1 Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Predicted to be involved in calcium-ion regulated exocytosis; cellular response to calcium ion; and regulation of secretion by cell. Predicted to be located in exocytic vesicle and plasma membrane. WB:WBGene00006307 suf-1 Predicted to enable mRNA binding activity. Predicted to be involved in RNA 3'-end processing. Predicted to be located in nucleus. Is an ortholog of human CSTF3 (cleavage stimulation factor subunit 3). WB:WBGene00006308 sul-1 Enables heparan sulfate 6-O-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification. Predicted to be located in Golgi stack; cell surface; and endoplasmic reticulum. Is an ortholog of human SULF1 (sulfatase 1) and SULF2 (sulfatase 2). WB:WBGene00006309 sul-2 Predicted to enable sulfuric ester hydrolase activity. Expressed in chemosensory neurons. Human ortholog(s) of this gene implicated in X-linked recessive disease (multiple); metachromatic leukodystrophy; and mucopolysaccharidosis IVA. Is an ortholog of human STS (steroid sulfatase). WB:WBGene00006310 sul-3 Predicted to enable sulfuric ester hydrolase activity. Human ortholog(s) of this gene implicated in mucopolysaccharidosis VI. Is an ortholog of human ARSI (arylsulfatase family member I) and ARSJ (arylsulfatase family member J). WB:WBGene00006311 sun-1 Predicted to enable protein-membrane adaptor activity. Involved in several processes, including centrosome localization; embryo development; and regulation of centrosome duplication. Located in nuclear envelope. Expressed in several structures, including Caa; Psub4; Z2; Z3; and germ line. Human ortholog(s) of this gene implicated in spermatogenic failure 16. Is an ortholog of human SUN5 (Sad1 and UNC84 domain containing 5). WB:WBGene00006313 sup-2 No description available WB:WBGene00006314 sup-5 Expressed in several structures, including body wall musculature; hermaphrodite gonad; hypodermis; intestine; and vulva. WB:WBGene00006315 sup-6 Is affected by several genes including daf-12; rrf-3; and pgl-1 based on tiling array and RNA-seq studies. Is affected by Tunicamycin and sodium arsenite based on RNA-seq studies. WB:WBGene00006316 sup-7 Expressed in several structures, including body wall musculature; hermaphrodite gonad; hypodermis; intestine; and vulva. WB:WBGene00006318 sup-9 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Involved in regulation of muscle contraction. Located in muscle cell projection membrane and striated muscle dense body. Expressed in body wall musculature; muscle cell; and neurons. Human ortholog(s) of this gene implicated in Birk-Barel syndrome and primary pulmonary hypertension. Is an ortholog of human KCNK3 (potassium two pore domain channel subfamily K member 3) and KCNK9 (potassium two pore domain channel subfamily K member 9). WB:WBGene00006319 sup-10 Enables potassium channel regulator activity. Involved in regulation of muscle contraction and regulation of potassium ion transport. Located in plasma membrane and striated muscle dense body. Expressed in anal depressor muscle; body wall musculature; head neurons; intestinal muscle; and vulval muscle. WB:WBGene00006320 sup-11 No description available WB:WBGene00006321 sup-12 Enables pre-mRNA intronic binding activity and single-stranded RNA binding activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; regulation of actin cytoskeleton organization; and regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck. Part of ribonucleoprotein complex. Is an ortholog of human RBM24 (RNA binding motif protein 24) and RBM38 (RNA binding motif protein 38). WB:WBGene00006322 sup-13 No description available WB:WBGene00006323 sup-16 No description available WB:WBGene00006324 sup-17 Predicted to enable metalloendopeptidase activity. Involved in several processes, including nematode male tail tip morphogenesis; positive regulation of transforming growth factor beta receptor signaling pathway; and vulval development. Located in cytoplasmic vesicle membrane and plasma membrane. Expressed in M lineage cell; hypodermis; intestinal cell; spermatheca; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease 18; colorectal cancer; and reticulate acropigmentation of Kitamura. Is an ortholog of human ADAM10 (ADAM metallopeptidase domain 10). WB:WBGene00006326 sup-19 No description available WB:WBGene00006327 sup-21 Expressed in body wall musculature; hermaphrodite gonad; hypodermis; intestine; and vulva. WB:WBGene00006328 sup-22 No description available WB:WBGene00006329 sup-23 No description available WB:WBGene00006330 sup-24 Expressed in several structures, including body wall musculature; hermaphrodite gonad; hypodermis; intestine; and vulva. WB:WBGene00006331 sup-26 Enables mRNA 3'-UTR binding activity. Involved in negative regulation of translation. Located in cytoplasm. Expressed in several structures, including gonad. Is an ortholog of human RBMS1 (RNA binding motif single stranded interacting protein 1); RBMS2 (RNA binding motif single stranded interacting protein 2); and RBMS3 (RNA binding motif single stranded interacting protein 3). WB:WBGene00006332 sup-27 No description available WB:WBGene00006333 sup-28 Expressed in body wall musculature; hermaphrodite gonad; hypodermis; intestine; and vulva. WB:WBGene00006334 sup-29 Expressed in body wall musculature; intestine; uterus; and vulva. WB:WBGene00006335 sup-30 No description available WB:WBGene00006336 sup-31 No description available WB:WBGene00006337 sup-32 No description available WB:WBGene00006338 sup-33 Expressed in several structures, including body wall musculature; hermaphrodite gonad; hypodermis; intestine; and vulva. WB:WBGene00006339 sup-34 Expressed in body wall musculature; egg-laying apparatus; hypodermis; intestine; and neurons. WB:WBGene00006342 sup-37 Involved in embryonic digestive tract morphogenesis. Located in nucleus. Expressed in neurons; pharynx; and spermatheca. WB:WBGene00006344 sup-39 Is affected by several genes including daf-12; etr-1; and rnp-6 based on tiling array and RNA-seq studies. WB:WBGene00006345 sup-40 No description available WB:WBGene00006346 sup-41 No description available WB:WBGene00006347 sup-42 No description available WB:WBGene00006348 sup-43 No description available WB:WBGene00006349 sur-2 Involved in defense response to Gram-positive bacterium; regulation of protein catabolic process; and regulation of transcription by RNA polymerase II. Part of mediator complex. Expressed in several structures, including P1.p; P2.p; P5.ppp; P7.paa; and vulval cell. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 18. Is an ortholog of human MED23 (mediator complex subunit 23). WB:WBGene00006350 sur-4 No description available WB:WBGene00006351 sur-5 Predicted to enable acetoacetate-CoA ligase activity. Predicted to be involved in fatty acid metabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; gonad; hypodermal cell; and somatic cell. Is an ortholog of human AACS (acetoacetyl-CoA synthetase). WB:WBGene00006352 sur-6 Predicted to enable protein phosphatase regulator activity. Involved in embryo development; nematode larval development; and positive regulation of vulval development. Predicted to be located in cytosol. Predicted to be part of protein phosphatase type 2A complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; spinocerebellar ataxia type 12; and systemic lupus erythematosus. Is an ortholog of human PPP2R2A (protein phosphatase 2 regulatory subunit Balpha) and PPP2R2D (protein phosphatase 2 regulatory subunit Bdelta). WB:WBGene00006353 sur-7 Involved in several processes, including cellular response to zinc ion; muscle cell cellular homeostasis; and positive regulation of Ras protein signal transduction. Located in endoplasmic reticulum membrane. Expressed in several structures, including hypodermis; muscle cell; pharynx; tail; and vulva. WB:WBGene00006354 sus-1 No description available WB:WBGene00006355 suv-2 No description available WB:WBGene00006356 suv-3 No description available WB:WBGene00006357 suv-4 No description available WB:WBGene00006358 suv-5 No description available WB:WBGene00006359 swp-1 Predicted to enable RNA binding activity. Predicted to be involved in mRNA 5'-splice site recognition. Is an ortholog of human SFSWAP (splicing factor SWAP). WB:WBGene00006360 syc-1 No description available WB:WBGene00006361 syc-2 No description available WB:WBGene00006362 syc-3 No description available WB:WBGene00006363 syd-1 Enables GTPase activator activity; Roundabout binding activity; and small GTPase binding activity. Involved in cell projection organization; cellular localization; and locomotion. Located in presynaptic membrane. Expressed in nerve ring and neurons. Is an ortholog of human SYDE2 (synapse defective Rho GTPase homolog 2). WB:WBGene00006364 syd-2 Enables several functions, including cytoskeletal motor activator activity; kinesin binding activity; and protein homodimerization activity. Involved in several processes, including anterograde synaptic vesicle transport; egg-laying behavior; and positive regulation of anterograde synaptic vesicle transport. Located in axon; cytoplasm; and presynaptic active zone dense projection. Expressed in several structures, including excretory gland cell; nervous system; pharyngeal gland cell; rectal gland cell; and uv1. Is an ortholog of human PPFIA3 (PTPRF interacting protein alpha 3). WB:WBGene00006365 syg-1 Enables cell adhesion molecule binding activity. Involved in actin filament bundle assembly; cell-cell signaling; and nervous system development. Located in axon and synapse. Expressed in amphid sheath cell; egg-laying apparatus; head muscle; hypodermis; and neurons. Used to study nephrotic syndrome. Human ortholog(s) of this gene implicated in nephrotic syndrome type 23. Is an ortholog of human KIRREL1 (kirre like nephrin family adhesion molecule 1) and KIRREL2 (kirre like nephrin family adhesion molecule 2). WB:WBGene00006366 sym-1 Located in extracellular space. Expressed in vulB1 and vulB2. WB:WBGene00006367 sym-2 Predicted to enable mRNA binding activity. Involved in embryo development; embryonic body morphogenesis; and multicellular organismal movement. Predicted to be located in nucleoplasm. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 109. Is an ortholog of human ESRP1 (epithelial splicing regulatory protein 1) and ESRP2 (epithelial splicing regulatory protein 2). WB:WBGene00006368 sym-3 Enriched in several structures, including ABalapapapa; ABalapppapa; ABplpaaappa; ABprpaaappa; and head neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by eight chemicals including Lithium Chloride; Zidovudine; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: N-terminal C2 in EEIG1 and EHBP1 proteins; EEIG1/2-like; and NT-type C2 domain. Is an ortholog of human EEIG1 (estrogen-induced osteoclastogenesis regulator 1) and EEIG2 (EEIG family member 2). WB:WBGene00006369 sym-4 Enriched in several structures, including ABalapapap; ABalapppap; excretory cell; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including rotenone; stavudine; and fluvastatin based on RNA-seq and microarray studies. Human WDR44 enables molecular sequestering activity and small GTPase binding activity. Is predicted to encode a protein with the following domains: WD40 repeat; WD domain, G-beta repeat; WD40-repeat-containing domain superfamily; WD repeat-containing protein WDR44/Dgr2; WD40/YVTN repeat-like-containing domain superfamily; and Phosphorylation site. Is an ortholog of human WDR44 (WD repeat domain 44). WB:WBGene00006371 syx-3 Predicted to enable SNAP receptor activity and SNARE binding activity. Involved in positive regulation of defecation and regulation of muscle contraction. Located in plasma membrane. WB:WBGene00006372 syx-2 Predicted to enable SNAP receptor activity and SNARE binding activity. Involved in short-term memory. Predicted to be located in presynaptic active zone membrane and synaptic vesicle. Predicted to be part of SNARE complex. Expressed in several structures, including head neurons; hypodermis; neurons; and ventral cord neurons. WB:WBGene00006373 syx-5 Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in Golgi membrane. Predicted to be part of SNARE complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Is an ortholog of human STX5 (syntaxin 5). WB:WBGene00006374 syx-4 Predicted to enable SNAP receptor activity and SNARE binding activity. Involved in cortical granule exocytosis; positive regulation of cytokinesis; and regulation of exocytosis. Located in cleavage furrow; cortical granule; and perinuclear region of cytoplasm. Expressed in gonad and seam cell. WB:WBGene00006375 syp-1 Enables protein homodimerization activity. Involved in positive regulation of reciprocal meiotic recombination; regulation of chromosome segregation; and synaptonemal complex assembly. Located in central element. Expressed in germ line. WB:WBGene00006376 syp-2 Involved in positive regulation of reciprocal meiotic recombination and synaptonemal complex assembly. Located in central element. WB:WBGene00006377 syp-3 Involved in chiasma assembly; embryo development; and synaptonemal complex assembly. Located in central element and lateral element. WB:WBGene00006378 syr-1 No description available WB:WBGene00006379 sys-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; scaffold protein binding activity; and transcription coactivator activity. Involved in several processes, including cell fate commitment involved in formation of primary germ layer; gonad development; and regulation of gene expression. Located in several cellular components, including cell cortex; kinetochore; and pericentriolar material. Expressed in several structures, including ABplpapaap; ABprpapaap; Z1.aa; posterior distal tip cell; and tail hypodermis. WB:WBGene00006380 tab-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head neurons; intestine; and lateral ganglion. Is an ortholog of human BSX (brain specific homeobox). WB:WBGene00006381 tac-1 Enables protein domain specific binding activity. Involved in several processes, including regulation of microtubule polymerization or depolymerization; sexual reproduction; and spindle organization. Located in cytoplasm; kinetochore; and microtubule cytoskeleton. WB:WBGene00006382 taf-1 Predicted to enable several functions, including RNA polymerase II general transcription initiation factor activity; TBP-class protein binding activity; and histone acetyltransferase activity. Predicted to contribute to transcription cis-regulatory region binding activity. Involved in embryo development and transcription initiation at RNA polymerase II promoter. Located in nucleus. Human ortholog(s) of this gene implicated in X-linked dystonia-parkinsonism and syndromic X-linked intellectual disability. Is an ortholog of human TAF1L (TATA-box binding protein associated factor 1 like). WB:WBGene00006383 taf-2 Predicted to enable chromatin binding activity and transcription cis-regulatory region binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in embryo development and transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 40. Is an ortholog of human TAF2 (TATA-box binding protein associated factor 2). WB:WBGene00006384 taf-3 Predicted to enable p53 binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Is an ortholog of human TAF3 (TATA-box binding protein associated factor 3). WB:WBGene00006385 taf-4 Predicted to enable DNA binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in several processes, including determination of adult lifespan; regulation of mitotic cell cycle, embryonic; and transcription initiation at RNA polymerase II promoter. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spermatogenic failure 13. Is an ortholog of human TAF4B (TATA-box binding protein associated factor 4b). WB:WBGene00006386 taf-5 Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in embryo development and transcription by RNA polymerase II. Located in nucleus. Is an ortholog of human TAF5 (TATA-box binding protein associated factor 5). WB:WBGene00006387 taf-6.1 Predicted to enable transcription coactivator activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Is an ortholog of human TAF6 (TATA-box binding protein associated factor 6). WB:WBGene00006388 taf-7.1 Predicted to enable histone acetyltransferase regulator activity and transcription coactivator activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Is an ortholog of human TAF7 (TATA-box binding protein associated factor 7) and TAF7L (TATA-box binding protein associated factor 7 like). WB:WBGene00006389 taf-7.2 Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Is an ortholog of human TAF7 (TATA-box binding protein associated factor 7) and TAF7L (TATA-box binding protein associated factor 7 like). WB:WBGene00006390 taf-8 Predicted to enable protein heterodimerization activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Is an ortholog of human TAF8 (TATA-box binding protein associated factor 8). WB:WBGene00006391 taf-9 Predicted to enable transcription coactivator activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in embryo development; positive regulation of transcription by RNA polymerase II; and regulation of mitotic cell cycle, embryonic. Located in nucleus. Is an ortholog of human TAF9 (TATA-box binding protein associated factor 9). WB:WBGene00006392 taf-10 Predicted to enable promoter-specific chromatin binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in embryo development; positive regulation of transcription by RNA polymerase II; and regulation of mitotic cell cycle, embryonic. Located in nucleus. Is an ortholog of human TAF10 (TATA-box binding protein associated factor 10). WB:WBGene00006393 taf-11.1 Predicted to enable transcription coactivator activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Is an ortholog of several human genes including LINC02218 (long intergenic non-protein coding RNA 2218); TAF11 (TATA-box binding protein associated factor 11); and TAF11L4 (TATA-box binding protein associated factor 11 like 4). WB:WBGene00006394 taf-11.2 Predicted to enable transcription coactivator activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Is an ortholog of several human genes including TAF11 (TATA-box binding protein associated factor 11); TAF11L4 (TATA-box binding protein associated factor 11 like 4); and TAF11L6 (TATA-box binding protein associated factor 11 like 6). WB:WBGene00006395 taf-11.3 Predicted to enable transcription coactivator activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Is an ortholog of human TAF11 (TATA-box binding protein associated factor 11). WB:WBGene00006396 taf-12 Predicted to enable DNA binding activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Located in nucleus. Is an ortholog of human TAF12 (TATA-box binding protein associated factor 12). WB:WBGene00006397 taf-13 Predicted to enable protein heterodimerization activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 60. Is an ortholog of human TAF13 (TATA-box binding protein associated factor 13). WB:WBGene00006399 tag-4 Enriched in several structures, including ABalppppppa; ABplaapapa; ABplaapappp; ABpraaapppa; and amphid neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including sir-2.1; csr-1; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00006402 fut-3 Enables 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity. Involved in fucosylation. Predicted to be located in Golgi cisterna membrane. Is an ortholog of human FUT5 (fucosyltransferase 5) and FUT6 (fucosyltransferase 6). WB:WBGene00006404 tag-10 Located in membrane raft. Expressed in amphid neurons. WB:WBGene00006405 itsn-1 Predicted to enable molecular adaptor activity. Involved in positive regulation of synaptic vesicle endocytosis. Located in endocytic vesicle and presynaptic periactive zone. Expressed in neurons; somatic nervous system; tail; and vulva. Is an ortholog of human ITSN2 (intersectin 2). WB:WBGene00006406 srgp-1 Enables GTPase activator activity; protein self-association; and small GTPase binding activity. Involved in negative regulation of cell migration; negative regulation of phagocytosis, engulfment; and regulation of cell-cell adhesion. Located in adherens junction and cell cortex. Expressed in hypodermis; nerve ring; somatic cell; and spermatheca. Human ortholog(s) of this gene implicated in thyroid gland papillary carcinoma. Is an ortholog of human SRGAP1 (SLIT-ROBO Rho GTPase activating protein 1) and SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2). WB:WBGene00006407 lim-9 Enables protein domain specific binding activity. Predicted to be involved in DNA-templated transcription. Located in M band. Expressed in several structures, including body wall musculature; excretory canal; non-striated muscle; spermatheca; and vulva. Is an ortholog of human FHL2 (four and a half LIM domains 2). WB:WBGene00006408 tag-18 Enriched in ABalppappa; ABarappppa; germ line; intestine; and muscle cell based on proteomic; Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00006409 hdl-2 Predicted to enable carboxy-lyase activity. Predicted to be involved in amino acid metabolic process. Predicted to be located in cytoplasm. WB:WBGene00006410 nck-1 Predicted to enable receptor tyrosine kinase binding activity and signaling adaptor activity. Predicted to be involved in cell migration and signal transduction. Located in cytoplasm and nucleus. Expressed in several structures, including egg-laying apparatus; gonad; hypodermis; neuroblasts; and neurons. Is an ortholog of human NCK1 (NCK adaptor protein 1) and NCK2 (NCK adaptor protein 2). WB:WBGene00006411 octr-1 Enables octopamine receptor activity. Involved in negative regulation of innate immune response; octopamine signaling pathway; and regulation of IRE1-mediated unfolded protein response. Predicted to be located in dendrite. Expressed in head neurons; sensory neurons; tail; uterine toroidal epithelial cell; and in male. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); attention deficit hyperactivity disorder; and type 2 diabetes mellitus. Is an ortholog of human ADRA2A (adrenoceptor alpha 2A). WB:WBGene00006412 nlg-1 Predicted to enable neurexin family protein binding activity and signaling receptor activity. Involved in gamma-aminobutyric acid receptor clustering and negative regulation of neurotransmitter secretion. Located in axon; dendrite; and synapse. Expressed in several structures, including body wall musculature; diagonal muscle; neurons; tail; and ventral nerve cord. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human NLGN4Y (neuroligin 4 Y-linked). WB:WBGene00006414 raga-1 Predicted to enable GTPase activity. Involved in several processes, including determination of adult lifespan; positive regulation of TOR signaling; and regulation of growth. Predicted to be located in lysosome and nucleus. Predicted to be part of Gtr1-Gtr2 GTPase complex. Expressed in several structures, including anterior hypodermis and gonad. Is an ortholog of human RRAGA (Ras related GTP binding A). WB:WBGene00006415 tag-30 Predicted to be involved in neurogenesis. Predicted to be located in P-body and cytosol. Expressed in body wall musculature; intestinal muscle; and rectal muscle. Is an ortholog of human BTBD2 (BTB domain containing 2). WB:WBGene00006416 sams-5 Predicted to enable methionine adenosyltransferase activity. Predicted to be involved in S-adenosylmethionine biosynthetic process. Predicted to be located in cytosol. Expressed in MI neuron. Human ortholog(s) of this gene implicated in hypermethioninemia and lung cancer. Is an ortholog of human MAT1A (methionine adenosyltransferase 1A) and MAT2A (methionine adenosyltransferase 2A). WB:WBGene00006418 spl-2 Predicted to enable sphinganine-1-phosphate aldolase activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in nephrotic syndrome type 14. Is an ortholog of human SGPL1 (sphingosine-1-phosphate lyase 1). WB:WBGene00006419 oac-39 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00006423 asd-2 Enables pre-mRNA intronic binding activity and single-stranded RNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Located in P granule and nucleus. Part of ribonucleoprotein complex. Expressed in body wall musculature; hypodermis; and pharyngeal muscle cell. Is an ortholog of human QKI (QKI, KH domain containing RNA binding). WB:WBGene00006424 ctbp-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in hypodermis and nervous system. Used to study alcohol use disorder. Is an ortholog of human CTBP1 (C-terminal binding protein 1) and CTBP2 (C-terminal binding protein 2). WB:WBGene00006428 tkr-3 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in tail. WB:WBGene00006429 arrd-3 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC5 (arrestin domain containing 5). WB:WBGene00006430 tag-51 Enriched in body wall musculature; germ line; and neurons based on RNA-seq and microarray studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by five chemicals including stavudine; paraquat; and Colistin based on RNA-seq and microarray studies. Is an ortholog of human TAF1A (TATA-box binding protein associated factor, RNA polymerase I subunit A). WB:WBGene00006431 tag-52 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in cytoplasm. Expressed in anchor cell; gonad; spermatheca; and uterine toroidal epithelial cell. WB:WBGene00006432 atrn-1 Predicted to be located in membrane. Is an ortholog of human ATRN (attractin) and ATRNL1 (attractin like 1). WB:WBGene00006433 sdhb-1 Predicted to enable iron-sulfur cluster binding activity and ubiquinone binding activity. Predicted to be involved in aerobic respiration and respiratory electron transport chain. Located in mitochondrion. Expressed in head and tail. Used to study paraganglioma. Human ortholog(s) of this gene implicated in several diseases, including Carney-Stratakis syndrome; gastrointestinal stromal tumor; and mitochondrial complex II deficiency. Is an ortholog of human SDHB (succinate dehydrogenase complex iron sulfur subunit B). WB:WBGene00006434 prdx-2 Enables thioredoxin peroxidase activity. Involved in several processes, including determination of adult lifespan; positive regulation of brood size; and response to inorganic substance. Located in cytoplasm. Expressed in body wall musculature; corpus; gonad; head; and tail. Human ortholog(s) of this gene implicated in colorectal cancer; methylmalonic aciduria and homocystinuria type cblC; and oral squamous cell carcinoma. Is an ortholog of human PRDX1 (peroxiredoxin 1) and PRDX2 (peroxiredoxin 2). WB:WBGene00006435 stdh-4 Predicted to enable oxidoreductase activity. Predicted to be involved in fatty acid elongation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). WB:WBGene00006436 ttn-1 Enables actin filament binding activity and myosin binding activity. Predicted to be involved in phosphorylation. Located in A band and I band. Expressed in muscle cell. WB:WBGene00006437 mrck-1 Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including embryonic body morphogenesis; positive regulation of endocytic recycling; and regulation of Golgi organization. Located in cytoplasm. Expressed in Ea and Ep. Used to study cerebral cavernous malformation. Is an ortholog of human CDC42BPA (CDC42 binding protein kinase alpha) and CDC42BPB (CDC42 binding protein kinase beta). WB:WBGene00006438 nrfl-1 Enables protein-membrane adaptor activity. Predicted to be involved in protein localization to plasma membrane. Located in apical plasma membrane. Expressed in excretory canal; pharyngeal muscle cell; and tail. Human ortholog(s) of this gene implicated in hypophosphatemic nephrolithiasis/osteoporosis 2. Is an ortholog of human NHERF1 (NHERF family PDZ scaffold protein 1) and NHERF2 (NHERF family PDZ scaffold protein 2). WB:WBGene00006439 ant-1.1 Predicted to enable ATP:ADP antiporter activity. Involved in determination of adult lifespan; mitochondrion organization; and positive regulation of apoptotic process. Located in mitochondrion. Expressed in several structures, including body wall musculature; hermaphrodite somatic gonadal cell; intestine; pharynx; and vulva. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6). WB:WBGene00006440 nefr-1 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Expressed in lateral ganglion; nerve ring; and neurons. Used to study Charcot-Marie-Tooth disease. WB:WBGene00006441 cpna-4 Predicted to enable calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion. Predicted to be located in plasma membrane. WB:WBGene00006442 tag-65 Predicted to enable nucleic acid binding activity. Predicted to be involved in intracellular calcium ion homeostasis. Predicted to be located in perinuclear region of cytoplasm. Is an ortholog of human CHERP (calcium homeostasis endoplasmic reticulum protein). WB:WBGene00006443 pak-2 Predicted to enable protein serine/threonine kinase activity. Involved in nematode larval development. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Is an ortholog of human PAK4 (p21 (RAC1) activated kinase 4). WB:WBGene00006444 shn-1 Predicted to enable ionotropic glutamate receptor binding activity and synaptic receptor adaptor activity. Involved in defecation and rhythmic behavior. Predicted to be located in dendritic spine; postsynaptic density; and postsynaptic membrane. Expressed in several structures, including amphid neurons; egg-laying apparatus; pharyngeal-intestinal valve; somatic nervous system; and sperm. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in Phelan-McDermid syndrome; autistic disorder; and schizophrenia 15. Is an ortholog of human SHANK1 (SH3 and multiple ankyrin repeat domains 1). WB:WBGene00006445 tag-68 Predicted to enable I-SMAD binding activity and transcription regulator inhibitor activity. Predicted to be involved in several processes, including SMAD protein signal transduction; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Predicted to be part of heteromeric SMAD protein complex. Expressed in head neurons; intestine; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including aortic valve disease 2; idiopathic pulmonary fibrosis; and liver disease (multiple). Is an ortholog of human SMAD6 (SMAD family member 6) and SMAD7 (SMAD family member 7). WB:WBGene00006446 atx-3 Enables cysteine-type deubiquitinase activity. Involved in chemical synaptic transmission. Located in cytoplasm and nucleus. Expressed in coelomocyte; head; somatic nervous system; and tail neurons. Used to study Machado-Joseph disease. Human ortholog(s) of this gene implicated in Machado-Joseph disease. Is an ortholog of human ATXN3 (ataxin 3) and ATXN3L (ataxin 3 like). WB:WBGene00006447 tag-72 Predicted to enable RNA binding activity and mRNA (guanine-N7-)-methyltransferase activity. Predicted to be involved in 7-methylguanosine mRNA capping. Predicted to be located in nucleus. Predicted to be part of mRNA cap binding activity complex. Is an ortholog of human RNMT (RNA guanine-7 methyltransferase). WB:WBGene00006448 glod-4 Involved in determination of adult lifespan and methylglyoxal metabolic process. Expressed widely. Is an ortholog of human GLOD4 (glyoxalase domain containing 4). WB:WBGene00006449 alg-4 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Involved in spermatogenesis. Predicted to be located in P granule. WB:WBGene00006450 tag-77 Predicted to enable guanyl-nucleotide exchange factor activity and metal ion binding activity. Predicted to be located in cytoplasm. Expressed in hermaphrodite gonad and somatic gonad precursor. Is an ortholog of human FGD5 (FYVE, RhoGEF and PH domain containing 5) and FGD6 (FYVE, RhoGEF and PH domain containing 6). WB:WBGene00006452 heh-1 Predicted to enable sterol binding activity. Predicted to be involved in sterol transport. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in Niemann-Pick disease type C2. Is an ortholog of human NPC2 (NPC intracellular cholesterol transporter 2). WB:WBGene00006454 aex-4 Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in positive regulation of defecation and positive regulation of protein secretion. Located in plasma membrane. WB:WBGene00006459 tag-89 Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to be located in dendrite. WB:WBGene00006460 ppm-1.A Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of stress-activated MAPK cascade. Predicted to be located in cytosol and nucleus. Is an ortholog of human PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A) and PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B). WB:WBGene00006461 tag-96 Predicted to enable galactokinase activity. Predicted to be involved in galactose metabolic process. Predicted to be located in cytosol. Is an ortholog of human GALK2 (galactokinase 2). WB:WBGene00006462 svh-5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine and neurons. Is an ortholog of human EHF (ETS homologous factor); ELF3 (E74 like ETS transcription factor 3); and ELF5 (E74 like ETS transcription factor 5). WB:WBGene00006463 nduf-2.2 Predicted to enable NAD binding activity; oxidoreductase activity, acting on NAD(P)H; and quinone binding activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in several diseases, including Leigh disease; multiple sclerosis; and nuclear type mitochondrial complex I deficiency 6. Is an ortholog of human NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2). WB:WBGene00006464 bath-47 Expressed in head. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00006465 fntb-1 Predicted to enable protein prenyltransferase activity and zinc ion binding activity. Predicted to contribute to protein farnesyltransferase activity. Predicted to be part of protein farnesyltransferase complex. Expressed in body wall musculature; neurons; pharyngeal muscle cell; rectal epithelial cell; and vulval cell. Is an ortholog of human CHURC1-FNTB (CHURC1-FNTB readthrough) and FNTB (farnesyltransferase, CAAX box, beta). WB:WBGene00006466 tag-115 Predicted to be involved in mRNA export from nucleus. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription export complex 2. Is an ortholog of human SAC3D1 (SAC3 domain containing 1). WB:WBGene00006467 magu-2 Predicted to be involved in several processes, including establishment or maintenance of cell polarity; morphogenesis of an epithelial sheet; and protein localization to plasma membrane. Predicted to be located in adherens junction and plasma membrane. Expressed in head; hypodermis; and pharyngeal muscle cell. Is an ortholog of human PALS1 (protein associated with LIN7 1, MAGUK p55 family member). WB:WBGene00006468 rhgf-1 Enables microtubule binding activity. Involved in axon regeneration. Located in neuronal cell body and varicosity. Expressed in nervous system and spermatheca. Human ortholog(s) of this gene implicated in immunodeficiency 62. Is an ortholog of human ARHGEF11 (Rho guanine nucleotide exchange factor 11). WB:WBGene00006470 tag-120 Predicted to be involved in negative regulation of apoptotic signaling pathway. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Expressed in excretory system; neurons; and pharyngeal muscle cell. Is an ortholog of human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1). WB:WBGene00006471 nhr-233 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in membrane and nucleus. WB:WBGene00006472 tag-123 Predicted to be involved in protein localization to membrane. Predicted to be located in membrane. Expressed in several structures, including anterior gonad arm; head; pharyngeal muscle cell; rectal epithelium; and vulva. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Is an ortholog of human TM9SF2 (transmembrane 9 superfamily member 2). WB:WBGene00006473 tag-124 Predicted to enable pseudouridine synthase activity. Predicted to be involved in mRNA pseudouridine synthesis and tRNA pseudouridine synthesis. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human PUS3 (pseudouridine synthase 3). WB:WBGene00006474 wdr-5.1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in determination of adult lifespan; programmed cell death; and transdifferentiation. Located in cytoplasm and nucleus. Part of MLL3/4 complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; hermaphrodite gonad; neurons; and somatic gonad precursor. Is an ortholog of human WDR5 (WD repeat domain 5). WB:WBGene00006475 tyra-3 Predicted to enable G protein-coupled serotonin receptor activity; neurotransmitter receptor activity; and octopamine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to be located in dendrite. Expressed in SDQ; gonad; head neurons; and vulva. Used to study Parkinson's disease. WB:WBGene00006476 rhgf-2 Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in several processes, including Rho protein signal transduction; embryonic body morphogenesis; and positive regulation of transcription by RNA polymerase II. Located in axon and cell body. Expressed in several structures, including pharyngeal cell; seam cell; somatic nervous system; tail; and touch receptor neurons. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate C and distal spinal muscular atrophy type 4. Is an ortholog of human PLEKHG5 (pleckstrin homology and RhoGEF domain containing G5). WB:WBGene00006477 chup-1 Enables cholesterol binding activity. Involved in cholesterol import. Located in intracellular membrane-bounded organelle and plasma membrane. Expressed in several structures, including anal depressor muscle; hypodermis; intestine; pharynx; and reproductive system. Is an ortholog of human SIDT1 (SID1 transmembrane family member 1). WB:WBGene00006478 tag-131 Predicted to be located in endomembrane system and membrane. Is an ortholog of human CYB5D2 (cytochrome b5 domain containing 2). WB:WBGene00006479 tmbi-4 Predicted to be involved in negative regulation of apoptotic process. Predicted to be located in membrane. Is an ortholog of human TMBIM4 (transmembrane BAX inhibitor motif containing 4). WB:WBGene00006481 plrg-1 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of Prp19 complex and catalytic step 2 spliceosome. Expressed in head and tail. Is an ortholog of human PLRG1 (pleiotropic regulator 1). WB:WBGene00006483 dgk-4 Predicted to enable ATP-dependent diacylglycerol kinase activity. Predicted to be involved in diacylglycerol metabolic process; intracellular signal transduction; and lipid phosphorylation. Expressed in gonad; head; and tail. Is an ortholog of human DGKD (diacylglycerol kinase delta) and DGKH (diacylglycerol kinase eta). WB:WBGene00006484 tag-138 Predicted to enable clathrin binding activity and phospholipid binding activity. Predicted to be involved in endocytosis. Is an ortholog of human HIP1R (huntingtin interacting protein 1 related). WB:WBGene00006486 zipt-16 Predicted to enable monoatomic cation:bicarbonate symporter activity and zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion import across plasma membrane. Predicted to be located in membrane. Expressed in tail. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIn. Is an ortholog of human SLC39A8 (solute carrier family 39 member 8). WB:WBGene00006487 zipt-17 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion transmembrane transport. Predicted to be located in membrane. Expressed in pharyngeal muscle cell. WB:WBGene00006488 F56D6.6 Predicted to be located in membrane. WB:WBGene00006489 zhit-3 Predicted to be involved in box C/D snoRNP assembly; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and snoRNA localization. Located in nucleus. Is an ortholog of human ZNHIT6 (zinc finger HIT-type containing 6). WB:WBGene00006490 kdin-1 Predicted to enable PDZ domain binding activity and protein kinase regulator activity. Predicted to be located in membrane. Expressed in excretory cell. Is an ortholog of human KIDINS220 (kinase D interacting substrate 220). WB:WBGene00006491 acl-3 Predicted to enable 1-acylglycerophosphocholine O-acyltransferase activity. Predicted to be involved in cardiolipin acyl-chain remodeling and inner mitochondrial membrane organization. Predicted to be located in mitochondrial membrane. Human ortholog(s) of this gene implicated in Barth syndrome and dilated cardiomyopathy. Is an ortholog of human TAFAZZIN (tafazzin, phospholipid-lysophospholipid transacylase). WB:WBGene00006492 let-391 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00006493 ivns-1 Enriched in body wall musculature; intestine; neurons; pharynx; and somatic gonad precursor based on Chronogram; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; proteomic; RNA-seq; and microarray studies. Is affected by ten chemicals including stavudine; Tunicamycin; and bortezomib based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in immunodeficiency 70. Is predicted to encode a protein with the following domains: BTB/POZ domain; Kelch-type beta propeller; Kelch motif; BTB/Kelch-associated; SKP1/BTB/POZ domain superfamily; Galactose oxidase/kelch, beta-propeller; and Kelch repeat type 1. Is an ortholog of human IVNS1ABP (influenza virus NS1A binding protein). WB:WBGene00006494 zipt-7.2 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion transmembrane transport. Predicted to be located in membrane. Expressed in somatic cell. Human ortholog(s) of this gene implicated in agammaglobulinemia 9. Is an ortholog of human SLC39A7 (solute carrier family 39 member 7). WB:WBGene00006495 cpna-1 Enables phosphatase binding activity and protein-macromolecule adaptor activity. Involved in positive regulation of sarcomere organization. Located in M band and striated muscle dense body. Expressed in body wall musculature. WB:WBGene00006496 cgef-1 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in protein localization. Located in cell cortex and nucleoplasm. Expressed in hermaphrodite gonad; neurons; somatic gonad precursor; and vulva. Is an ortholog of human MCF2 (MCF.2 cell line derived transforming sequence); MCF2L (MCF.2 cell line derived transforming sequence like); and MCF2L2 (MCF.2 cell line derived transforming sequence-like 2). WB:WBGene00006497 tag-151 Predicted to enable GTP binding activity; GTPase activity; and U3 snoRNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of preribosome, small subunit precursor. Is an ortholog of human TSR1 (TSR1 ribosome maturation factor). WB:WBGene00006498 ten-1 Involved in several processes, including body morphogenesis; inductive cell migration; and system development. Located in nucleus and plasma membrane. Expressed in several structures, including body muscle cell; gonad; hypodermis; interfacial epithelial cell; and neurons. Human ortholog(s) of this gene implicated in essential tremor 5. Is an ortholog of human TENM2 (teneurin transmembrane protein 2) and TENM3 (teneurin transmembrane protein 3). WB:WBGene00006499 tag-153 Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening and regulation of stem cell population maintenance. Predicted to be located in P-body. Predicted to be part of CCR4-NOT core complex. WB:WBGene00006503 snx-3 Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in endocytic recycling and late endosome to Golgi transport. Located in endosome. Expressed in several structures, including pharynx and rectal epithelial cell. Is an ortholog of human SNX12 (sorting nexin 12) and SNX3 (sorting nexin 3). WB:WBGene00006504 kcc-1 Enables potassium:chloride symporter activity. Involved in chloride transmembrane transport and potassium ion transmembrane transport. Predicted to be located in plasma membrane. Expressed in several structures, including hermaphrodite distal tip cell; pharyngeal muscle cell; tail neurons; ventral nerve cord; and vulva. WB:WBGene00006505 lagr-1 Predicted to enable sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 8. Is an ortholog of human CERS1 (ceramide synthase 1). WB:WBGene00006508 tns-1 Predicted to enable protein tyrosine phosphatase activity. Involved in positive regulation of axon regeneration. Located in axon. Expressed in DD neuron; VD neuron; head; and intestinal muscle. Is an ortholog of human TNS1 (tensin 1). WB:WBGene00006509 tag-164 Predicted to be located in membrane. WB:WBGene00006510 mtrr-1 Predicted to enable FMN binding activity; [methionine synthase] reductase activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in homocysteine metabolic process and methionine biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including endocrine gland cancer (multiple); hematologic cancer (multiple); and homocystinuria. Is an ortholog of human MTRR (5-methyltetrahydrofolate-homocysteine methyltransferase reductase). WB:WBGene00006512 abcf-1 Predicted to enable ATP binding activity. Is an ortholog of human ABCF1 (ATP binding cassette subfamily F member 1). WB:WBGene00006513 rimb-1 Predicted to be involved in neuromuscular synaptic transmission. Predicted to be located in synapse. Expressed in dorsal nerve cord; head ganglion; nervous system; tail ganglion; and ventral nerve cord. Human ortholog(s) of this gene implicated in dystonia. Is an ortholog of human RIMBP2 (RIMS binding protein 2) and TSPOAP1 (TSPO associated protein 1). WB:WBGene00006514 tdp-1 Enables chromatin binding activity and single-stranded RNA binding activity. Involved in several processes, including RNA splicing; determination of adult lifespan; and hyperosmotic response. Located in nucleus. Expressed in several structures, including body wall musculature; intestine; muscle cell; neurons; and pharynx. Used to study amyotrophic lateral sclerosis type 10. Human ortholog(s) of this gene implicated in Alzheimer's disease; Lewy body dementia; and progressive supranuclear palsy. Is an ortholog of human TARDBP (TAR DNA binding protein). WB:WBGene00006515 txdc-9 Involved in microtubule cytoskeleton organization. Located in cytoplasm and nucleus. Expressed in nervous system; pharynx; and vulva. Is an ortholog of human TXNDC9 (thioredoxin domain containing 9). WB:WBGene00006516 vps-16 Predicted to enable actin binding activity. Involved in digestive tract development and embryo development. Predicted to be located in endosome. Predicted to be part of HOPS complex. Human ortholog(s) of this gene implicated in dystonia. Is an ortholog of human VPS16 (VPS16 core subunit of CORVET and HOPS complexes). WB:WBGene00006517 madd-3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleus. Expressed in anal depressor muscle; anal sphincter muscle; body wall musculature; and vulval muscle. Is an ortholog of human CLK2 (CDC like kinase 2). WB:WBGene00006518 bckd-1B Predicted to enable catalytic activity. Involved in positive regulation of fatty acid biosynthetic process and positive regulation of nematode larval development. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial alpha-ketoglutarate dehydrogenase complex. Human ortholog(s) of this gene implicated in maple syrup urine disease. Is an ortholog of human BCKDHB (branched chain keto acid dehydrogenase E1 subunit beta). WB:WBGene00006519 cox-6A Predicted to enable enzyme regulator activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate D and cytochrome-c oxidase deficiency disease. Is an ortholog of human COX6A2 (cytochrome c oxidase subunit 6A2). WB:WBGene00006520 egli-1 Predicted to be located in endoplasmic reticulum membrane. Expressed in head; neurons; spermatheca; and vulva. Is an ortholog of human TMEM41B (transmembrane protein 41B). WB:WBGene00006522 abcx-1 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in positive regulation of nematode male tail tip morphogenesis. Predicted to be located in membrane. Expressed in hyp11; hyp8; and hyp9. Human ortholog(s) of this gene implicated in several diseases, including arteriosclerosis; obesity; and sitosterolemia. Is an ortholog of human ABCG8 (ATP binding cassette subfamily G member 8). WB:WBGene00006523 tam-1 Predicted to enable ubiquitin protein ligase activity. Involved in several processes, including chromosome segregation; negative regulation of vulval development; and transcription initiation-coupled chromatin remodeling. Located in germ cell nucleus. Expressed in several structures, including germ line. WB:WBGene00006524 tap-1 Enables mitogen-activated protein kinase kinase kinase binding activity and protein kinase activator activity. Involved in endodermal cell fate specification and negative regulation of Ras protein signal transduction. Predicted to be located in cytosol and nucleus. Expressed in cholinergic neurons; coelomocyte; and somatic neurons. Is an ortholog of human TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1). WB:WBGene00006525 tax-2 Contributes to intracellular cGMP-activated cation channel activity. Involved in several processes, including G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; negative regulation of cGMP-mediated signaling; and positive regulation of macromolecule metabolic process. Part of cation channel complex. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in achromatopsia 3 and retinitis pigmentosa 45. Is an ortholog of human CNGB1 (cyclic nucleotide gated channel subunit beta 1) and CNGB3 (cyclic nucleotide gated channel subunit beta 3). WB:WBGene00006526 tax-4 Enables identical protein binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Involved in several processes, including detection of stimulus; regulation of growth; and response to temperature stimulus. Located in ciliary inversin compartment; dendrite; and non-motile cilium. Part of cation channel complex. Human ortholog(s) of this gene implicated in achromatopsia 2 and retinitis pigmentosa 49. Is an ortholog of human CNGA1 (cyclic nucleotide gated channel subunit alpha 1) and CNGA2 (cyclic nucleotide gated channel subunit alpha 2). WB:WBGene00006527 tax-6 Enables calcium ion binding activity and calmodulin-dependent protein phosphatase activity. Involved in several processes, including determination of adult lifespan; male mating behavior; and response to temperature stimulus. Located in several cellular components, including neuronal cell body; nucleus; and plasma membrane bounded cell projection. Expressed in several structures, including germ line; head neurons; muscle cell; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including aortic valve stenosis; cholangiocarcinoma; and developmental and epileptic encephalopathy 91. Is an ortholog of human PPP3CB (protein phosphatase 3 catalytic subunit beta) and PPP3CC (protein phosphatase 3 catalytic subunit gamma). WB:WBGene00006528 tba-1 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in embryo development; establishment of mitotic spindle orientation; and regulation of cytokinesis. Located in axon; somatodendritic compartment; and spindle. Expressed in several structures, including ganglia; germ line; intestine; neurons; and somatic nervous system. Is an ortholog of human TUBAL3 (tubulin alpha like 3). WB:WBGene00006529 tba-2 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in several processes, including centrosome localization; establishment of mitotic spindle orientation; and regulation of cytokinesis. Predicted to be located in cytoplasm and microtubule. Expressed in several structures, including body wall musculature; intestine; neurons; pharynx; and ventral nerve cord. Human ortholog(s) of this gene implicated in thrombocytopenia. Is an ortholog of human TUBA8 (tubulin alpha 8) and TUBAL3 (tubulin alpha like 3). WB:WBGene00006530 tba-4 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoplasm and microtubule. Is an ortholog of human TUBAL3 (tubulin alpha like 3). WB:WBGene00006531 tba-5 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in axonemal microtubule. Expressed in amphid neurons and phasmid neurons. WB:WBGene00006532 tba-6 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoplasm and microtubule. Expressed in HSN; ciliated neurons; intestine; and vulva. WB:WBGene00006533 tba-7 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoplasm and microtubule. Expressed in touch receptor neurons. WB:WBGene00006534 tba-8 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoplasm and microtubule. Expressed in germ line; posterior lateral ganglion; retrovesicular ganglion; seam cell; and ventral cord neurons. WB:WBGene00006535 tba-9 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoplasm and microtubule. Expressed in RIG; accessory cell; ciliated neurons; ventral cord neurons; and vulval muscle. WB:WBGene00006536 tbb-1 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in spindle microtubule. Expressed in several structures, including excretory gland cell; intestine; nervous system; pharynx; and uv1. Human ortholog(s) of this gene implicated in brain disease (multiple) and congenital symmetric circumferential skin creases 1. Is an ortholog of human TUBB (tubulin beta class I) and TUBB4A (tubulin beta 4A class IVa). WB:WBGene00006537 tbb-2 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in meiotic spindle organization. Located in spindle microtubule. Expressed in several structures, including germ line; gonad; oocyte; tail; and touch receptor neurons. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 1 and congenital fibrosis of the extraocular muscles 3A. Is an ortholog of several human genes including TUBB3 (tubulin beta 3 class III); TUBB6 (tubulin beta 6 class V); and TUBB8B (tubulin beta 8B). WB:WBGene00006538 tbb-4 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in axonemal microtubule. Expressed in HSN; accessory cell; epithelial cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Leber congenital amaurosis with early-onset deafness; complex cortical dysplasia with other brain malformations (multiple); and congenital symmetric circumferential skin creases 1. Is an ortholog of human TUBB4B (tubulin beta 4B class IVb). WB:WBGene00006539 tbb-6 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in PERK-mediated unfolded protein response. Predicted to be located in cytoplasm and microtubule. Expressed in pharynx. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 1 and congenital fibrosis of the extraocular muscles 3A. Is an ortholog of several human genes including TUBB3 (tubulin beta 3 class III); TUBB6 (tubulin beta 6 class V); and TUBB8B (tubulin beta 8B). WB:WBGene00006540 tbg-1 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in several processes, including maintenance of centrosome location; organelle organization; and regulation of cell cycle. Located in centrosome and cytoplasm. Expressed in gonad. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 4 and inclusion body myositis. Is an ortholog of human TUBG2 (tubulin gamma 2). WB:WBGene00006541 tbh-1 Enables tyramine-beta hydroxylase activity. Involved in octopamine biosynthetic process. Located in synapse. Expressed in RICL; RICR; and gonad. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; and dopamine beta-hydroxylase deficiency. Is an ortholog of human DBH (dopamine beta-hydroxylase). WB:WBGene00006542 tbp-1 Enables DNA-binding transcription factor activity; RNA polymerase II general transcription initiation factor binding activity; and minor groove of adenine-thymine-rich DNA binding activity. Involved in positive regulation of DNA-templated transcription. Located in nucleus. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; sleep apnea; and type 1 diabetes mellitus. Is an ortholog of human TBP (TATA-box binding protein) and TBPL2 (TATA-box binding protein like 2). WB:WBGene00006543 tbx-2 Enables DNA-binding transcription repressor activity; core promoter sequence-specific DNA binding activity; and enzyme binding activity. Involved in several processes, including muscle structure development; neuron migration; and olfactory behavior. Located in cytoplasm and nucleus. Expressed in amphid neurons; body wall musculature; head neurons; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); ulnar-mammary syndrome; and vertebral anomalies and variable endocrine and T-cell dysfunction. Is an ortholog of human TBX2 (T-box transcription factor 2) and TBX3 (T-box transcription factor 3). WB:WBGene00006544 tbx-7 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. WB:WBGene00006545 tbx-8 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic body morphogenesis. Located in nucleus. Expressed in several structures, including Eal; Ear; Epl; Epr; and intestine. Human ortholog(s) of this gene implicated in several diseases, including Holt-Oram syndrome; asthma, nasal polyps, and aspirin intolerance; and malaria. Is an ortholog of several human genes including EOMES (eomesodermin); TBR1 (T-box brain transcription factor 1); and TBX5 (T-box transcription factor 5). WB:WBGene00006546 tbx-9 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in embryonic body morphogenesis. Located in nucleus. Expressed in several structures, including ABarpa; Eal; Ear; Epl; and Epr. Human ortholog(s) of this gene implicated in several diseases, including Holt-Oram syndrome; asthma, nasal polyps, and aspirin intolerance; and malaria. Is an ortholog of several human genes including EOMES (eomesodermin); TBR1 (T-box brain transcription factor 1); and TBX5 (T-box transcription factor 5). WB:WBGene00006547 tbx-11 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00006549 tbx-30 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00006550 tbx-31 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00006551 tbx-32 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00006552 tbx-33 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00006553 tbx-34 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00006554 tbx-35 Enables sequence-specific DNA binding activity. Involved in cell fate specification; pharyngeal muscle development; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including MSaa; MSpa; MSpp; head neurons; and intestine. WB:WBGene00006555 tbx-36 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00006556 tbx-37 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pharynx development. Located in nucleus. Expressed in head neurons. Human ortholog(s) of this gene implicated in Abruzzo-Erickson syndrome; X-linked cleft palate with or without ankyloglossia; and bone disease (multiple). Is an ortholog of several human genes including TBX15 (T-box transcription factor 15); TBX4 (T-box transcription factor 4); and TBX6 (T-box transcription factor 6). WB:WBGene00006557 tbx-38 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pharynx development. Located in nucleus. Expressed in head neurons. Human ortholog(s) of this gene implicated in Abruzzo-Erickson syndrome; X-linked cleft palate with or without ankyloglossia; and bone disease (multiple). Is an ortholog of several human genes including TBX15 (T-box transcription factor 15); TBX4 (T-box transcription factor 4); and TBX6 (T-box transcription factor 6). WB:WBGene00006558 tbx-39 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head muscle; head neurons; intestine; tail neurons; and ventral nerve cord. WB:WBGene00006559 tbx-40 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in phasmid neurons. Human ortholog(s) of this gene implicated in Abruzzo-Erickson syndrome; X-linked cleft palate with or without ankyloglossia; and bone disease (multiple). Is an ortholog of several human genes including TBX15 (T-box transcription factor 15); TBX4 (T-box transcription factor 4); and TBX6 (T-box transcription factor 6). WB:WBGene00006560 tbx-41 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00006561 tcl-2 Involved in asymmetric cell division. Located in cytoplasm and nucleus. Expressed in several structures, including TL.p; TR.p; inner labial neurons; seam cell; and tail neurons. WB:WBGene00006562 tdc-1 Enables tyrosine decarboxylase activity. Involved in octopamine biosynthetic process. Located in axon and neuronal cell body. Expressed in hermaphrodite gonad and lateral ganglion. Human ortholog(s) of this gene implicated in several diseases, including aromatic L-amino acid decarboxylase deficiency; bipolar disorder; and hyperinsulinism. Is an ortholog of human DDC (dopa decarboxylase). WB:WBGene00006563 teg-1 Involved in positive regulation of miRNA processing and positive regulation of stem cell differentiation. Located in cytoplasm and nucleoplasm. Expressed in seam cell; uterus; and vulva. Is an ortholog of human CD2BP2 (CD2 cytoplasmic tail binding protein 2). WB:WBGene00006565 tfg-1 Predicted to enable identical protein binding activity. Involved in several processes, including cellular localization; regulation of cell growth; and regulation of cell size. Located in endoplasmic reticulum exit site and mitochondrion. Expressed in germ line; hypodermis; intestine; and muscle cell. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 57. Is an ortholog of human TFG (trafficking from ER to golgi regulator). WB:WBGene00006566 tgt-1 Predicted to enable tRNA-guanosine(34) queuine transglycosylase activity. Predicted to be involved in tRNA-guanine transglycosylation. Predicted to be located in cytoplasm. Is an ortholog of human QTRT1 (queuine tRNA-ribosyltransferase catalytic subunit 1). WB:WBGene00006567 tgt-2 Predicted to enable metal ion binding activity and tRNA-guanosine(34) queuine transglycosylase activity. Predicted to be involved in tRNA-guanine transglycosylation. Predicted to be located in cytoplasm. Is an ortholog of human QTRT2 (queuine tRNA-ribosyltransferase accessory subunit 2). WB:WBGene00006568 thk-1 Predicted to enable thymidine kinase activity. Predicted to be involved in thymidine metabolic process. Human ortholog(s) of this gene implicated in breast cancer; cervix carcinoma; and lung non-small cell carcinoma. Is an ortholog of human TK1 (thymidine kinase 1). WB:WBGene00006569 tig-1 No description available WB:WBGene00006570 tig-2 Predicted to enable cytokine activity. Predicted to be located in extracellular space. Expressed in cholinergic neurons; pharyngeal muscle cell; and touch receptor neurons. Human ortholog(s) of this gene implicated in breast cancer; renal cell carcinoma; and reproductive organ cancer (multiple). Is an ortholog of several human genes including BMP5 (bone morphogenetic protein 5); BMP7 (bone morphogenetic protein 7); and BMP8B (bone morphogenetic protein 8b). WB:WBGene00006571 tim-1 Predicted to enable DNA binding activity. Involved in embryo development; regulation of sister chromatid cohesion; and sister chromatid cohesion. Located in nucleus. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome. Is an ortholog of human TIMELESS (timeless circadian regulator). WB:WBGene00006572 tin-9.1 Predicted to enable metal ion binding activity. Involved in protein insertion into mitochondrial inner membrane; regulation of growth; and reproduction. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human TIMM9 (translocase of inner mitochondrial membrane 9). WB:WBGene00006573 tin-10 Predicted to enable metal ion binding activity. Involved in protein insertion into mitochondrial inner membrane; regulation of growth; and reproduction. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human TIMM10 (translocase of inner mitochondrial membrane 10). WB:WBGene00006574 tin-13 Predicted to enable metal ion binding activity. Predicted to be involved in protein insertion into mitochondrial inner membrane. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial intermembrane space protein transporter complex. Is an ortholog of human TIMM13 (translocase of inner mitochondrial membrane 13). WB:WBGene00006575 tir-1 Enables several functions, including NAD+ nucleosidase activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including NAD catabolic process; defense response to other organism; and regulation of gene expression. Acts upstream of or within serotonin biosynthetic process. Located in axon cytoplasm and cell body. Expressed in head. Used to study amyotrophic lateral sclerosis. Is an ortholog of human SARM1 (sterile alpha and TIR motif containing 1). WB:WBGene00006576 tkr-1 Predicted to enable tachykinin receptor activity. Predicted to be involved in tachykinin receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in ADEsoL; ADEsoR; PDEsoL; and PDEsoR. Human ortholog(s) of this gene implicated in exercise-induced bronchoconstriction and hypogonadotropic hypogonadism 11 with or without anosmia. Is an ortholog of human TACR1 (tachykinin receptor 1) and TACR3 (tachykinin receptor 3). WB:WBGene00006577 tlf-1 Predicted to enable general transcription initiation factor activity. Involved in embryo development; positive regulation of protein phosphorylation; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of chromatin. Expressed in several structures, including germ line. Is an ortholog of human TBPL1 (TATA-box binding protein like 1). WB:WBGene00006578 tli-1 Predicted to enable ubiquitin binding activity and ubiquitin conjugating enzyme binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Expressed in head and tail. Is an ortholog of human TOLLIP (toll interacting protein). WB:WBGene00006579 tlk-1 Enables protein serine/threonine kinase activity. Involved in regulation of transcription by RNA polymerase II. Located in nucleus. Part of chromatin. Expressed in germ line; head; posterior lateral ganglion; somatic cell; and somatic gonad. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Is an ortholog of human TLK2 (tousled like kinase 2). WB:WBGene00006580 tlp-1 Predicted to enable metal ion binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including body wall musculature; rectal valve cell; somatic nervous system; tail precursor cell; and tail spike. Is an ortholog of human ZNF503 (zinc finger protein 503) and ZNF703 (zinc finger protein 703). WB:WBGene00006582 tmd-2 Predicted to enable tropomyosin binding activity. Predicted to be involved in actin filament organization and myofibril assembly. Located in myofibril. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2G. Is an ortholog of human LMOD2 (leiomodin 2) and TMOD4 (tropomodulin 4). WB:WBGene00006583 tnc-2 Enables troponin I binding activity. Is an ortholog of human CALML6 (calmodulin like 6). WB:WBGene00006584 tni-1 Enables troponin C binding activity. Involved in backward locomotion. Part of muscle thin filament tropomyosin. Expressed in several structures, including body wall musculature; gonad; non-striated muscle; rectal muscle; and in male. Human ortholog(s) of this gene implicated in several diseases, including arthrogryposis multiplex congenita; distal arthrogryposis type 2B1; and intrinsic cardiomyopathy (multiple). Is an ortholog of human TNNI1 (troponin I1, slow skeletal type); TNNI2 (troponin I2, fast skeletal type); and TNNI3 (troponin I3, cardiac type). WB:WBGene00006585 tni-3 Enables troponin C binding activity. Involved in egg-laying behavior; muscle contraction; and post-embryonic body morphogenesis. Located in sarcomere. Expressed in body wall musculature; non-striated muscle; rectal muscle; and in male. Is an ortholog of human TNNI1 (troponin I1, slow skeletal type). WB:WBGene00006586 tni-4 Enables troponin C binding activity. Involved in embryo development and pharyngeal pumping. Located in sarcomere. Expressed in pharyngeal muscle cell and pharynx. Human ortholog(s) of this gene implicated in several diseases, including arthrogryposis multiplex congenita; distal arthrogryposis type 2B1; and intrinsic cardiomyopathy (multiple). Is an ortholog of human TNNI1 (troponin I1, slow skeletal type); TNNI2 (troponin I2, fast skeletal type); and TNNI3 (troponin I3, cardiac type). WB:WBGene00006587 tnt-2 Predicted to enable tropomyosin binding activity. Predicted to be involved in muscle contraction and sarcomere organization. Predicted to be part of troponin complex. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; intrinsic cardiomyopathy (multiple); and muscle tissue disease (multiple). Is an ortholog of human TNNT1 (troponin T1, slow skeletal type); TNNT2 (troponin T2, cardiac type); and TNNT3 (troponin T3, fast skeletal type). WB:WBGene00006588 tnt-3 Predicted to enable tropomyosin binding activity. Predicted to be involved in muscle contraction and sarcomere organization. Predicted to be part of troponin complex. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; intrinsic cardiomyopathy (multiple); and muscle tissue disease (multiple). Is an ortholog of human TNNT1 (troponin T1, slow skeletal type); TNNT2 (troponin T2, cardiac type); and TNNT3 (troponin T3, fast skeletal type). WB:WBGene00006589 tnt-4 Predicted to enable tropomyosin binding activity. Involved in several processes, including nematode larval development; pharyngeal gland morphogenesis; and pharynx development. Predicted to be part of troponin complex. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; intrinsic cardiomyopathy (multiple); and muscle tissue disease (multiple). Is an ortholog of human TNNT1 (troponin T1, slow skeletal type); TNNT2 (troponin T2, cardiac type); and TNNT3 (troponin T3, fast skeletal type). WB:WBGene00006590 toc-1 Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in zinc ion transport. Predicted to be located in Golgi apparatus. Is an ortholog of human SLC30A6 (solute carrier family 30 member 6). WB:WBGene00006591 toh-1 Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in arcade cell; egg-laying apparatus; hyp7 syncytium; intestine; and neuronal sheath cell. WB:WBGene00006592 dpy-31 Predicted to enable metalloendopeptidase activity. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in extracellular region. Expressed in several structures, including amphid sheath cell; excretory duct; hypodermis; socket cell; and vulva. WB:WBGene00006593 tol-1 Predicted to enable signaling receptor activity. Involved in defense response to Gram-negative bacterium and embryo development. Predicted to be located in extracellular matrix and extracellular space. Expressed in neurons. Is an ortholog of several human genes including CHAD (chondroadherin); ELFN2 (extracellular leucine rich repeat and fibronectin type III domain containing 2); and TRIL (TLR4 interactor with leucine rich repeats). WB:WBGene00006594 tom-1 Predicted to enable GTPase activator activity; myosin II binding activity; and syntaxin binding activity. Involved in several processes, including regulation of neurotransmitter levels; regulation of synaptic vesicle docking; and regulation of synaptic vesicle priming. Located in GABA-ergic synapse; cholinergic synapse; and neuromuscular junction. Is extrinsic component of neuronal dense core vesicle membrane. Part of SNARE complex. Expressed in head neurons; tail neurons; and ventral cord neurons. Is an ortholog of human STXBP5 (syntaxin binding protein 5). WB:WBGene00006595 top-1 Enables DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA replication; DNA topological change; and chromosome segregation. Located in nucleolus and spindle pole centrosome. Expressed in several structures, including IL socket cell; excretory cell; gonad; neurons; and oocyte. Is an ortholog of human TOP1 (DNA topoisomerase I) and TOP1MT (DNA topoisomerase I mitochondrial). WB:WBGene00006596 top-3 Enables DNA topoisomerase type I (single strand cut, ATP-independent) activity. Involved in DNA topological change. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 5. Is an ortholog of human TOP3A (DNA topoisomerase III alpha). WB:WBGene00006597 tor-1 Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in cellular response to misfolded protein. Predicted to be located in endoplasmic reticulum lumen. Expressed in anal depressor muscle; head mesodermal cell; head neurons; and intestinal muscle. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-5 and torsion dystonia 1. Is an ortholog of human TOR1A (torsin family 1 member A) and TOR1B (torsin family 1 member B). WB:WBGene00006598 tor-2 Predicted to enable ATP binding activity and ATP hydrolysis activity. Involved in cellular response to misfolded protein; negative regulation of gene expression; and regulation of neuron apoptotic process. Located in endoplasmic reticulum. Expressed in neurons. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-5 and torsion dystonia 1. Is an ortholog of human TOR1A (torsin family 1 member A) and TOR1B (torsin family 1 member B). WB:WBGene00006599 tpa-1 Enables mitogen-activated protein kinase kinase kinase binding activity and protein serine/threonine kinase activity. Involved in several processes, including defense response to other organism; positive regulation of antimicrobial peptide production; and positive regulation of axon regeneration. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including autoimmune lymphoproliferative syndrome type 3; fatty liver disease; and portal hypertension. Is an ortholog of human PRKCD (protein kinase C delta) and PRKCQ (protein kinase C theta). WB:WBGene00006600 tph-1 Predicted to enable tryptophan 5-monooxygenase activity. Involved in several processes, including determination of adult lifespan; locomotory exploration behavior; and positive regulation of transforming growth factor beta receptor signaling pathway. Located in cytosol and neuron projection. Expressed in CP neuron; nerve ring; and pharynx. Used to study alcohol use disorder and cocaine abuse. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; alcohol use disorder; attention deficit hyperactivity disorder; and autistic disorder. Is an ortholog of human TPH1 (tryptophan hydroxylase 1) and TPH2 (tryptophan hydroxylase 2). WB:WBGene00006601 tpi-1 Predicted to enable methylglyoxal synthase activity and triose-phosphate isomerase activity. Involved in cell redox homeostasis and determination of adult lifespan. Located in myofibril. Human ortholog(s) of this gene implicated in triosephosphate isomerase deficiency. Is an ortholog of human TPI1 (triosephosphate isomerase 1). WB:WBGene00006602 tps-1 Predicted to enable alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity. Predicted to contribute to trehalose-phosphatase activity. Predicted to be involved in trehalose biosynthetic process and trehalose metabolism in response to stress. Predicted to be part of alpha,alpha-trehalose-phosphate synthase complex (UDP-forming). Expressed in CAN; gonad; hypodermis; intestine; and isthmus. WB:WBGene00006603 tps-2 Predicted to enable alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity. Predicted to contribute to trehalose-phosphatase activity. Predicted to be involved in trehalose biosynthetic process and trehalose metabolism in response to stress. Predicted to be part of alpha,alpha-trehalose-phosphate synthase complex (UDP-forming). Expressed in hypodermis. WB:WBGene00006604 tra-1 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process. Located in cytoplasm and nucleus. Expressed in several structures, including AWA; germ line; gonad; intestine; and somatic cell. Human ortholog(s) of this gene implicated in several diseases, including Culler-Jones syndrome; gastrointestinal system cancer (multiple); and synostosis (multiple). Is an ortholog of human GLI1 (GLI family zinc finger 1); GLI2 (GLI family zinc finger 2); and GLI3 (GLI family zinc finger 3). WB:WBGene00006605 tra-2 Enables transmembrane signaling receptor activity. Involved in developmental process involved in reproduction and oocyte fate determination. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. Expressed in germ line. WB:WBGene00006606 tra-3 Enables cysteine-type endopeptidase activity. Involved in proteolysis and sex determination. Predicted to be located in cytoplasm. Expressed in several structures, including excretory cell; hypodermis; intestine; ventral nerve cord; and vulva. Human ortholog(s) of this gene implicated in neovascular inflammatory vitreoretinopathy. Is an ortholog of human CAPN5 (calpain 5). WB:WBGene00006607 tre-1 Predicted to enable alpha,alpha-trehalase activity. Predicted to be involved in trehalose catabolic process. Is an ortholog of human TREH (trehalase). WB:WBGene00006608 tre-2 Predicted to enable alpha,alpha-trehalase activity. Predicted to be involved in trehalose catabolic process. Is an ortholog of human TREH (trehalase). WB:WBGene00006609 tre-3 Predicted to enable alpha,alpha-trehalase activity. Predicted to be involved in trehalose catabolic process. Located in membrane raft. Expressed in head and tail. Is an ortholog of human TREH (trehalase). WB:WBGene00006610 tre-4 Predicted to enable alpha,alpha-trehalase activity. Predicted to be involved in trehalose catabolic process. Predicted to be located in membrane. Expressed in neurons and tail. Is an ortholog of human TREH (trehalase). WB:WBGene00006611 tre-5 Predicted to enable alpha,alpha-trehalase activity. Predicted to be involved in trehalose catabolic process. Expressed in head. Is an ortholog of human TREH (trehalase). WB:WBGene00006612 trf-1 Predicted to enable zinc ion binding activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in cytoplasm. Expressed in CEMDL; CEMDR; CEMVL; CEMVR; and tail. Human ortholog(s) of this gene implicated in brain disease and lung adenocarcinoma. Is an ortholog of human TRAF4 (TNF receptor associated factor 4). WB:WBGene00006613 trm-1 Predicted to enable tRNA (guanine-N2-)-methyltransferase activity. Predicted to be involved in tRNA N2-guanine methylation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 68. Is an ortholog of human TRMT1 (tRNA methyltransferase 1). WB:WBGene00006614 trp-1 Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in calcium ion transmembrane transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Expressed in neurons and non-striated muscle. Used to study nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including cerebellar ataxia type 41; chronic fatigue syndrome; and focal segmental glomerulosclerosis 2. Is an ortholog of human TRPC3 (transient receptor potential cation channel subfamily C member 3); TRPC6 (transient receptor potential cation channel subfamily C member 6); and TRPC7 (transient receptor potential cation channel subfamily C member 7). WB:WBGene00006615 trp-2 Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in calcium ion transmembrane transport and regulation of cytosolic calcium ion concentration. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Expressed in ASER; SMDDL; SMDDR; SMDVL; and SMDVR. Used to study nicotine dependence. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1H; lung cancer; and stomach cancer. Is an ortholog of human TRPC4 (transient receptor potential cation channel subfamily C member 4) and TRPC5 (transient receptor potential cation channel subfamily C member 5). WB:WBGene00006616 trp-4 Predicted to enable calcium channel activity. Predicted to be involved in sensory perception of mechanical stimulus. Predicted to be located in membrane. Expressed in dopaminergic neurons; dorsal-rectal ganglion neurons; head mesodermal cell; mechanosensory neurons; and rectum. Is an ortholog of human ANKRD28 (ankyrin repeat domain 28) and ANKRD44 (ankyrin repeat domain 44). WB:WBGene00006617 tars-1 Predicted to enable threonine-tRNA ligase activity. Involved in determination of adult lifespan. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 21 and nonphotosensitive trichothiodystrophy 7. Is an ortholog of human TARS3 (threonyl-tRNA synthetase 3). WB:WBGene00006618 trt-1 Predicted to enable DNA binding activity; metal ion binding activity; and telomerase RNA reverse transcriptase activity. Involved in telomere maintenance via telomerase. Predicted to be located in chromosome, telomeric region and nucleus. Used to study cancer. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); and urinary system cancer (multiple). Is an ortholog of human TERT (telomerase reverse transcriptase). WB:WBGene00006619 try-1 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Expressed in germ line. Is an ortholog of human PRSS33 (serine protease 33). WB:WBGene00006620 svh-1 Predicted to enable serine-type endopeptidase activity. Involved in several processes, including axon regeneration; positive regulation of multicellular organismal process; and protein destabilization. Predicted to be located in extracellular space. Expressed in ADLL and ADLR. Human ortholog(s) of this gene implicated in enterokinase deficiency. Is an ortholog of human TMPRSS15 (transmembrane serine protease 15). WB:WBGene00006621 try-3 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00006622 try-4 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00006623 try-5 Predicted to enable serine-type endopeptidase activity. Involved in spermatid development. Located in extracellular space and secretory vesicle. Expressed in several structures, including head; male gonad; male gonadal cell; tail; and uterus. WB:WBGene00006624 try-6 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00006625 try-7 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00006626 tsn-1 Predicted to enable RNA binding activity and nuclease activity. Involved in miRNA-mediated gene silencing. Located in cytosol and nucleus. Part of RISC complex. Expressed in head and tail. Is an ortholog of human SND1 (staphylococcal nuclease and tudor domain containing 1). WB:WBGene00006627 tsp-1 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00006628 tsp-2 Predicted to be located in membrane. WB:WBGene00006629 tsp-3 Predicted to be located in membrane. WB:WBGene00006630 tsp-4 Predicted to be located in membrane. Is an ortholog of several human genes including TSPAN1 (tetraspanin 1); TSPAN2 (tetraspanin 2); and TSPAN4 (tetraspanin 4). WB:WBGene00006631 tsp-5 Predicted to be located in membrane. Is an ortholog of human TSPAN1 (tetraspanin 1); TSPAN18 (tetraspanin 18); and TSPAN4 (tetraspanin 4). WB:WBGene00006632 tsp-6 Predicted to be located in membrane. Expressed in AWAL; AWAR; amphid neurons; and phasmid neurons. Human ortholog(s) of this gene implicated in several diseases, including breast carcinoma; reproductive organ cancer (multiple); and severe acute respiratory syndrome. Is an ortholog of human CD9 (CD9 molecule). WB:WBGene00006633 tsp-7 Predicted to be located in membrane. Expressed in DA neuron; head neurons; tail neurons; touch receptor neurons; and ventral cord neurons. Human ortholog(s) of this gene implicated in carotid artery disease and diabetic neuropathy. Is an ortholog of human CD63 (CD63 molecule). WB:WBGene00006634 tsp-8 Predicted to be located in membrane. WB:WBGene00006635 tsp-9 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency 6. Is an ortholog of human CD81 (CD81 molecule). WB:WBGene00006636 tsp-10 Predicted to be located in membrane. WB:WBGene00006637 tsp-11 Predicted to be located in membrane. WB:WBGene00006638 tsp-12 Enables protease binding activity. Involved in several processes, including nematode male tail tip morphogenesis; positive regulation of egg-laying behavior; and regulation of developmental process. Located in cytoplasmic vesicle membrane and plasma membrane. Expressed in several structures, including M lineage cell; germ line; intestine; pharynx; and vulval precursor cell. Used to study cancer. Is an ortholog of human TSPAN14 (tetraspanin 14); TSPAN17 (tetraspanin 17); and TSPAN5 (tetraspanin 5). WB:WBGene00006639 tsp-13 Predicted to be located in membrane. WB:WBGene00006640 tsp-14 Enables protease binding activity. Involved in several processes, including nematode male tail tip morphogenesis; positive regulation of egg-laying behavior; and regulation of developmental process. Predicted to be located in plasma membrane. Expressed in several structures, including germ line; nose; sperm; vulva; and vulval precursor cell. Used to study cancer. Is an ortholog of human TSPAN10 (tetraspanin 10). WB:WBGene00006641 tsp-15 Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and skin epidermis development. Predicted to be located in membrane. Expressed in body wall musculature; hyp7 syncytium; pharynx; seam cell; and vulva. WB:WBGene00006642 tsp-16 Predicted to be located in membrane. Is an ortholog of human UPK1B (uroplakin 1B). WB:WBGene00006643 tsp-17 Enables D2 dopamine receptor binding activity. Involved in cellular response to paraquat; negative regulation of response to oxidative stress; and regulation of dopamine uptake involved in synaptic transmission. Located in neuron projection; perinuclear region of cytoplasm; and plasma membrane. Expressed in several structures, including NSM; body wall musculature; dopaminergic neurons; hermaphrodite gonad; and vulva. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 58. Is an ortholog of human TSPAN3 (tetraspanin 3) and TSPAN7 (tetraspanin 7). WB:WBGene00006644 tsp-18 Predicted to be located in membrane. WB:WBGene00006645 tsp-19 Predicted to be located in membrane. WB:WBGene00006646 tsp-20 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex. Is an ortholog of several human genes including CD151 (CD151 molecule (Raph blood group)); CD37 (CD37 molecule); and TSPAN16 (tetraspanin 16). WB:WBGene00006647 tsr-1 Predicted to be involved in protein import into nucleus. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 2. Is an ortholog of human TNPO3 (transportin 3). WB:WBGene00006648 ttb-1 Predicted to enable RNA polymerase II general transcription initiation factor activity and TBP-class protein binding activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription preinitiation complex. Is an ortholog of human GTF2B (general transcription factor IIB). WB:WBGene00006649 tth-1 Predicted to enable actin monomer binding activity. Predicted to be involved in actin filament organization. Predicted to be located in cytosol. Expressed in distal tip cell; nerve ring; oocyte; spermatheca; and terminal bulb. WB:WBGene00006650 tts-1 Enriched in muscle cell and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including Ethanol; Nitric Oxide; and methylmercury hydroxide based on RNA-seq and microarray studies. WB:WBGene00006651 tts-2 Enriched in head mesodermal cell; intestine; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twenty-two chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq and microarray studies. WB:WBGene00006652 ttx-1 Enables DNA-binding transcription factor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including regulation of plasma membrane bounded cell projection assembly; thermosensory behavior; and transcription by RNA polymerase II. Located in nucleus. Expressed in head neurons and pharyngeal cell. Human ortholog(s) of this gene implicated in panhypopituitarism and syndromic microphthalmia 5. Is an ortholog of human OTX1 (orthodenticle homeobox 1). WB:WBGene00006653 ttx-2 No description available WB:WBGene00006654 ttx-3 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including neuron differentiation; regulation of developmental process; and response to temperature stimulus. Predicted to be located in nucleus. Expressed in head muscle; head neurons; and pharyngeal neurons. Is an ortholog of human LHX9 (LIM homeobox 9). WB:WBGene00006655 tub-1 Involved in positive regulation of neurogenesis and receptor localization to non-motile cilium. Located in cytoplasm; non-motile cilium; and periciliary membrane compartment. Expressed in neurons. Used to study obesity. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 15; obesity; and retinitis pigmentosa 14. Is an ortholog of human TUB (TUB bipartite transcription factor); TULP1 (TUB like protein 1); and TULP3 (TUB like protein 3). WB:WBGene00006656 twk-1 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in distal tip cell; gonadal sheath cell; and hypodermis. WB:WBGene00006657 twk-2 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in neurons. WB:WBGene00006658 twk-3 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in RIGL; RIGR; neurons; and pharynx. WB:WBGene00006659 twk-4 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in sensory neurons. WB:WBGene00006660 twk-5 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006661 twk-6 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in hypodermis and tail. Is an ortholog of several human genes including KCNK2 (potassium two pore domain channel subfamily K member 2); KCNK4 (potassium two pore domain channel subfamily K member 4); and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00006662 twk-7 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in neurons and ventral nerve cord. Is an ortholog of human KCNK17 (potassium two pore domain channel subfamily K member 17) and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00006663 twk-8 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in body wall musculature. WB:WBGene00006664 twk-9 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006665 twk-10 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006666 twk-11 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006667 twk-12 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006668 twk-13 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in cholinergic neurons and ventral cord neurons. WB:WBGene00006669 twk-14 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Is an ortholog of human KCNK12 (potassium two pore domain channel subfamily K member 12). WB:WBGene00006670 twk-16 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in DVA and interneuron. WB:WBGene00006671 twk-17 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in neurons. Is an ortholog of human KCNK17 (potassium two pore domain channel subfamily K member 17) and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00006672 twk-18 Enables outward rectifier potassium channel activity. Involved in locomotion; muscle contraction; and potassium ion transport. Predicted to be located in membrane. Expressed in body wall musculature. WB:WBGene00006673 twk-20 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in muscle cell and neurons. Human ortholog(s) of this gene implicated in Birk-Barel syndrome and primary pulmonary hypertension. Is an ortholog of human KCNK3 (potassium two pore domain channel subfamily K member 3) and KCNK9 (potassium two pore domain channel subfamily K member 9). WB:WBGene00006674 twk-21 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Is an ortholog of several human genes including KCNK2 (potassium two pore domain channel subfamily K member 2); KCNK4 (potassium two pore domain channel subfamily K member 4); and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00006675 twk-22 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in pharynx. Is an ortholog of several human genes including KCNK2 (potassium two pore domain channel subfamily K member 2); KCNK4 (potassium two pore domain channel subfamily K member 4); and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00006676 twk-23 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in intestine; muscle cell; and neurons. Is an ortholog of human KCNK2 (potassium two pore domain channel subfamily K member 2). WB:WBGene00006677 twk-24 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006678 twk-25 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006679 twk-26 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Is an ortholog of several human genes including KCNK2 (potassium two pore domain channel subfamily K member 2); KCNK4 (potassium two pore domain channel subfamily K member 4); and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00006680 twk-28 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in body wall musculature. WB:WBGene00006681 twk-29 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in interneuron. WB:WBGene00006682 twk-30 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in DD neuron; motor neurons; neurons; and ventral cord neurons. WB:WBGene00006683 twk-31 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006684 twk-32 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in interneuron. WB:WBGene00006685 twk-33 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Is an ortholog of several human genes including KCNK2 (potassium two pore domain channel subfamily K member 2); KCNK4 (potassium two pore domain channel subfamily K member 4); and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00006686 twk-34 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Is an ortholog of several human genes including KCNK2 (potassium two pore domain channel subfamily K member 2); KCNK4 (potassium two pore domain channel subfamily K member 4); and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00006687 twk-35 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006688 twk-36 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in excretory cell. WB:WBGene00006689 twk-37 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Is an ortholog of human KCNK17 (potassium two pore domain channel subfamily K member 17). WB:WBGene00006690 twk-39 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in migraine. Is an ortholog of human KCNK18 (potassium two pore domain channel subfamily K member 18). WB:WBGene00006691 twk-40 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in cholinergic neurons and ventral cord neurons. WB:WBGene00006692 twk-42 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006693 twk-43 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in cholinergic neurons and ventral cord neurons. WB:WBGene00006694 twk-44 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00006695 twk-45 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Is an ortholog of several human genes including KCNK2 (potassium two pore domain channel subfamily K member 2); KCNK4 (potassium two pore domain channel subfamily K member 4); and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00006696 twk-46 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in NSML; NSMR; PDEL; and PDER. Is an ortholog of human KCNK1 (potassium two pore domain channel subfamily K member 1) and KCNK6 (potassium two pore domain channel subfamily K member 6). WB:WBGene00006697 uaf-1 Enables pre-mRNA 3'-splice site binding activity. Involved in several processes, including embryonic body morphogenesis; mRNA 3'-splice site recognition; and nematode larval development. Located in nucleoplasm. Is an ortholog of human U2AF2 (U2 small nuclear RNA auxiliary factor 2). WB:WBGene00006698 uaf-2 Enables pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U2AF complex and spliceosomal complex. Is an ortholog of human U2AF1 (U2 small nuclear RNA auxiliary factor 1) and U2AF1L4 (U2 small nuclear RNA auxiliary factor 1 like 4). WB:WBGene00006699 uba-1 Predicted to enable ubiquitin activating enzyme activity. Involved in several processes, including developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and protein metabolic process. Located in nucleus. Expressed in anterior hypodermis; germ line; midbody; neurons; and pharynx. Human ortholog(s) of this gene implicated in VEXAS syndrome and X-linked spinal muscular atrophy 2. Is an ortholog of human UBA1 (ubiquitin like modifier activating enzyme 1). WB:WBGene00006700 uba-2 Enables SUMO activating enzyme activity. Involved in several processes, including anterior/posterior pattern specification; nematode larval development; and protein sumoylation. Predicted to be located in cytoplasm. Predicted to be part of SUMO activating enzyme complex. Is an ortholog of human UBA2 (ubiquitin like modifier activating enzyme 2). WB:WBGene00006701 ubc-1 Enables ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Involved in DNA repair and protein ubiquitination. Part of ubiquitin conjugating enzyme complex. Expressed in head and tail. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Nascimento type. Is an ortholog of human UBE2B (ubiquitin conjugating enzyme E2 B). WB:WBGene00006702 ubc-3 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Is an ortholog of human CDC34 (cell division cycle 34, ubiqiutin conjugating enzyme) and UBE2R2 (ubiquitin conjugating enzyme E2 R2). WB:WBGene00006703 ubc-6 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be located in nucleus. Expressed in germ line and oocyte. Is an ortholog of human UBE2J1 (ubiquitin conjugating enzyme E2 J1). WB:WBGene00006704 ubc-7 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Is an ortholog of human UBE2G1 (ubiquitin conjugating enzyme E2 G1). WB:WBGene00006705 ubc-8 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Is an ortholog of human UBE2H (ubiquitin conjugating enzyme E2 H). WB:WBGene00006706 ubc-9 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; SAM domain binding activity; and SUMO conjugating enzyme activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; pharyngeal muscle development; and protein sumoylation. Predicted to be located in nucleus. Expressed in body wall musculature; coelomocyte; pharynx; tail; and in male. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; ovarian cancer; and urinary bladder cancer. Is an ortholog of human UBE2I (ubiquitin conjugating enzyme E2 I). WB:WBGene00006707 ubc-12 Enables NEDD8 transferase activity. Involved in negative regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of nematode male tail tip morphogenesis; and protein neddylation. Predicted to be located in cytoplasm. Expressed in hyp10. Is an ortholog of human UBE2F (ubiquitin conjugating enzyme E2 F (putative)). WB:WBGene00006708 ubc-13 Contributes to ubiquitin-protein transferase activity. Involved in protein ubiquitination and regulation of protein localization to cell surface. Part of ubiquitin conjugating enzyme complex. Expressed in several structures, including intestinal cell. Is an ortholog of human UBE2N (ubiquitin conjugating enzyme E2 N) and UBE2NL (ubiquitin conjugating enzyme E2 N like (gene/pseudogene)). WB:WBGene00006709 ubc-14 Predicted to enable ATP binding activity and transferase activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be located in cytosol and endoplasmic reticulum. Is an ortholog of human UBE2G2 (ubiquitin conjugating enzyme E2 G2). WB:WBGene00006710 ubc-15 Enables ubiquitin protein ligase binding activity. WB:WBGene00006711 ubc-16 Predicted to enable ubiquitin conjugating enzyme activity. Involved in protein ubiquitination. Predicted to be located in nucleus. Expressed in germ line and oocyte. Is an ortholog of human UBE2W (ubiquitin conjugating enzyme E2 W). WB:WBGene00006712 ubc-17 Predicted to enable cysteine-type endopeptidase inhibitor activity and ubiquitin conjugating enzyme activity. Predicted to be involved in negative regulation of apoptotic process. Predicted to be located in nucleus. Is an ortholog of human BIRC6 (baculoviral IAP repeat containing 6). WB:WBGene00006713 ubc-18 Enables ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Involved in determination of adult lifespan; embryonic digestive tract morphogenesis; and protein metabolic process. Acts upstream of or within animal organ morphogenesis. Predicted to be located in nucleus. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human UBE2L3 (ubiquitin conjugating enzyme E2 L3) and UBE2L5 (ubiquitin conjugating enzyme E2 L5). WB:WBGene00006714 ubc-19 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in DNA damage response. Predicted to be located in nucleus. Is an ortholog of human AKTIP (AKT interacting protein). WB:WBGene00006715 ubc-20 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Is an ortholog of human UBE2K (ubiquitin conjugating enzyme E2 K). WB:WBGene00006716 ubc-21 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Is an ortholog of human UBE2K (ubiquitin conjugating enzyme E2 K). WB:WBGene00006717 ubc-22 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be located in nucleus. WB:WBGene00006718 ubc-23 Predicted to enable ubiquitin binding activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum and nucleus. Expressed in intestinal cell. Is an ortholog of human FAF1 (Fas associated factor 1). WB:WBGene00006719 ubc-24 Predicted to enable NEDD8 transferase activity. Predicted to be involved in protein neddylation. Predicted to be located in nucleus. WB:WBGene00006720 ubc-25 Predicted to enable ubiquitin conjugating enzyme activity. Involved in locomotion. Located in cytosol; neuronal cell body; and nucleus. Expressed in body wall musculature; embryonic cell; non-striated muscle; and somatic nervous system. Is an ortholog of human UBE2Q1 (ubiquitin conjugating enzyme E2 Q1). WB:WBGene00006721 ubh-1 Enables deNEDDylase activity and deubiquitinase activity. Involved in negative regulation of dauer larval development and positive regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in cytoplasm. Expressed in amphid neurons and intestinal cell. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and hereditary spastic paraplegia 79. Is an ortholog of human UCHL1 (ubiquitin C-terminal hydrolase L1) and UCHL3 (ubiquitin C-terminal hydrolase L3). WB:WBGene00006722 ubh-2 Enables deNEDDylase activity and deubiquitinase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Expressed in intestinal cell and neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and hereditary spastic paraplegia 79. Is an ortholog of human UCHL1 (ubiquitin C-terminal hydrolase L1) and UCHL3 (ubiquitin C-terminal hydrolase L3). WB:WBGene00006723 ubh-3 Enables deNEDDylase activity and deubiquitinase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Expressed in intestinal cell and neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and hereditary spastic paraplegia 79. Is an ortholog of human UCHL1 (ubiquitin C-terminal hydrolase L1) and UCHL3 (ubiquitin C-terminal hydrolase L3). WB:WBGene00006724 ubh-4 Enables cysteine-type deubiquitinase activity. Involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Expressed in intestine; muscle cell; and neurons. Is an ortholog of human UCHL5 (ubiquitin C-terminal hydrolase L5). WB:WBGene00006725 ubl-1 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human RPS27A (ribosomal protein S27a) and RPS27AP5 (ribosomal protein S27a pseudogene 5). WB:WBGene00006726 ubl-5 Predicted to enable protein tag activity. Involved in mitochondrial unfolded protein response and positive regulation of gene expression. Located in cytosol and nucleus. Part of transcription regulator complex. Expressed in intestine; pharynx; and terminal bulb. Is an ortholog of human UBL5 (ubiquitin like 5). WB:WBGene00006727 ubq-1 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Involved in programmed cell death involved in cell development and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in body wall musculature. Is an ortholog of human UBC (ubiquitin C). WB:WBGene00006728 ubq-2 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Involved in polarity specification of anterior/posterior axis. Predicted to be located in cytoplasm; nucleus; and ribosome. Predicted to be part of ribonucleoprotein complex. Expressed in several structures, including hermaphrodite gonad; intestine; pharyngeal-intestinal valve; pharynx; and somatic nervous system. Human ortholog(s) of this gene implicated in colon carcinoma. Is an ortholog of human UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1). WB:WBGene00006729 ucp-4 Predicted to enable transmembrane transporter activity. Involved in response to cold. Predicted to be located in membrane. Expressed in head muscle; head neurons; hypodermis; pharyngeal muscle cell; and pharynx. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human SLC25A27 (solute carrier family 25 member 27). WB:WBGene00006730 uev-1 Enables ubiquitin conjugating enzyme binding activity. Involved in regulation of locomotion involved in locomotory behavior and regulation of protein localization to cell surface. Located in cytosol; neuron projection; and nucleus. Expressed in several structures, including anus; distal tip cell; germ line; neurons; and ventral nerve cord. Is an ortholog of human UBE2V2 (ubiquitin conjugating enzyme E2 V2). WB:WBGene00006731 uev-2 Predicted to be located in nucleus. WB:WBGene00006732 uev-3 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in DNA damage response. Predicted to be located in nucleus. Expressed in several structures, including ventral cord neurons. WB:WBGene00006733 ufd-1 Predicted to enable polyubiquitin modification-dependent protein binding activity. Involved in ER-associated misfolded protein catabolic process; embryo development; and positive regulation of protein localization to nucleus. Located in nucleus. Part of VCP-NPL4-UFD1 AAA ATPase complex. Used to study velocardiofacial syndrome. Human ortholog(s) of this gene implicated in DiGeorge syndrome and schizophrenia. Is an ortholog of human UFD1 (ubiquitin recognition factor in ER associated degradation 1). WB:WBGene00006734 ufd-2 Enables protein-folding chaperone binding activity; ubiquitin protein ligase binding activity; and ubiquitin-ubiquitin ligase activity. Involved in determination of adult lifespan; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein ubiquitination. Located in cytoplasm and nucleus. Expressed in body wall musculature; hypodermis; neurons; and pharyngeal muscle cell. Is an ortholog of human UBE4B (ubiquitination factor E4B). WB:WBGene00006735 ula-1 Predicted to enable NEDD8 activating enzyme activity. Involved in negative regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human NAE1 (NEDD8 activating enzyme E1 subunit 1). WB:WBGene00006736 ulp-1 Predicted to enable deSUMOylase activity. Involved in embryo development; positive regulation of error-prone translesion synthesis; and regulation of protein localization. Predicted to be located in nucleus. Is an ortholog of human SENP2 (SUMO specific peptidase 2). WB:WBGene00006737 ulp-2 Predicted to enable deSUMOylase activity. Involved in adherens junction maintenance and regulation of cell-cell adhesion involved in gastrulation. Located in cytosol and nucleus. Expressed in hypodermis and neuroblasts. WB:WBGene00006738 ulp-3 Predicted to enable deNEDDylase activity. Predicted to be involved in proteolysis. Is an ortholog of human SENP8 (SUMO peptidase family member, NEDD8 specific). WB:WBGene00006739 ulp-4 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and deSUMOylase activity. Involved in innate immune response and positive regulation of protein import into nucleus. Acts upstream of or within determination of adult lifespan and mitochondrial unfolded protein response. Located in mitochondrial matrix. Expressed in HSNL; HSNR; body wall musculature; hypodermis; and pharynx. Is an ortholog of human SENP7 (SUMO specific peptidase 7). WB:WBGene00006740 ulp-5 Predicted to enable deSUMOylase activity. Predicted to be involved in proteolysis. Predicted to be located in nucleus. WB:WBGene00006741 unc-1 Enables ion channel regulator activity. Involved in positive regulation of cell communication by electrical coupling and response to xenobiotic stimulus. Located in axon and gap junction. Expressed in several structures, including enteric muscle; ganglia; head neurons; somatic nervous system; and vulval muscle. WB:WBGene00006742 unc-2 Predicted to enable high voltage-gated calcium channel activity. Involved in several processes, including determination of left/right asymmetry in nervous system; negative regulation of transforming growth factor beta receptor signaling pathway; and response to heat. Located in presynaptic active zone membrane. Expressed in several structures, including body wall musculature; excretory canal; nerve ring; neurons; and pharyngeal muscle cell. Used to study migraine. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system (multiple); brain disease (multiple); and episodic ataxia type 2. Is an ortholog of human CACNA1B (calcium voltage-gated channel subunit alpha1 B). WB:WBGene00006743 unc-3 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; histone acetyltransferase binding activity; and identical protein binding activity. Involved in several processes, including dauer larval development; neuron differentiation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in ABalappaap; ABalappaapp; and neurons. Human ortholog(s) of this gene implicated in hypotonia, ataxia, and delayed development syndrome. Is an ortholog of several human genes including EBF1 (EBF transcription factor 1); EBF2 (EBF transcription factor 2); and EBF4 (EBF family member 4). WB:WBGene00006744 unc-4 Enables DNA-binding transcription factor activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; nervous system development; and synaptic vesicle transport. Located in axon and nucleus. Expressed in I5 neuron; cholinergic neurons; and somatic nervous system. WB:WBGene00006745 unc-5 Enables netrin receptor activity and protein tyrosine kinase binding activity. Involved in several processes, including axon guidance; regulation of neuron projection development; and sex differentiation. Acts upstream of or within distal tip cell migration. Located in axonal growth cone. Expressed in several structures, including distal tip cell; excretory canal; head neurons; motor neurons; and somatic nervous system. Is an ortholog of human UNC5A (unc-5 netrin receptor A); UNC5B (unc-5 netrin receptor B); and UNC5C (unc-5 netrin receptor C). WB:WBGene00006746 unc-6 Predicted to enable signaling receptor binding activity. Involved in several processes, including axon guidance; regulation of locomotion; and sex differentiation. Acts upstream of or within dendrite morphogenesis. Located in axon; basement membrane; and cytoplasm. Expressed in several structures, including P1; VA12; accessory cell; interneuron; and somatic neurons. Human ortholog(s) of this gene implicated in congenital mirror movement disorder. Is an ortholog of human NTN1 (netrin 1). WB:WBGene00006747 unc-7 Enables gap junction channel activity. Involved in several processes, including regulation of multicellular organismal process; reproductive behavior; and response to anesthetic. Located in gap junction and neuron projection membrane. Expressed in several structures, including OL socket cell; intestine; muscle cell; neurons; and pharyngeal gland cell. WB:WBGene00006748 unc-8 Predicted to enable ligand-gated sodium channel activity. Involved in locomotion. Located in neuronal cell body. Expressed in neurons. Human ortholog(s) of this gene implicated in bronchiectasis (multiple) and renal tubular transport disease (multiple). Is an ortholog of human SCNN1B (sodium channel epithelial 1 subunit beta); SCNN1D (sodium channel epithelial 1 subunit delta); and SCNN1G (sodium channel epithelial 1 subunit gamma). WB:WBGene00006749 unc-9 Enables actin filament binding activity and gap junction channel activity. Involved in monoatomic ion transmembrane transport and positive regulation of locomotion. Located in gap junction. Expressed in several structures, including anchor cell; muscle cell; neurons; phasmid sheath cell; and somatic nervous system. WB:WBGene00006750 unc-10 Enables small GTPase binding activity. Involved in several processes, including chemical synaptic transmission; defecation; and positive regulation of cholinergic synaptic transmission. Located in axon and presynaptic active zone. Expressed in dorsal nerve cord; nerve ring; nervous system; uv1; and ventral nerve cord. Is an ortholog of human RIMS1 (regulating synaptic membrane exocytosis 1). WB:WBGene00006751 unc-11 Predicted to enable SNARE binding activity; clathrin heavy chain binding activity; and phosphatidylinositol binding activity. Involved in several processes, including endocytosis; necroptotic process; and protein localization to postsynaptic membrane. Located in clathrin-coated pit and presynaptic membrane. Expressed in several structures, including epithelial cell; excretory gland cell; pharyngeal gland cell; rectal gland cell; and somatic nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease and acute myeloid leukemia. Is an ortholog of human PICALM (phosphatidylinositol binding clathrin assembly protein) and SNAP91 (synaptosome associated protein 91). WB:WBGene00006752 unc-13 Predicted to enable calmodulin binding activity and syntaxin-1 binding activity. Involved in regulation of multicellular organismal process; spermatogenesis; and synaptic vesicle exocytosis. Located in presynaptic active zone. Expressed in head neurons; neurons; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is an ortholog of human UNC13C (unc-13 homolog C). WB:WBGene00006753 unc-14 Enables protein kinase binding activity and scaffold protein binding activity. Involved in regulation of protein localization and synaptic vesicle localization. Located in neuron projection. Expressed in several structures, including hypodermis; intestine; motor neurons; muscle cell; and uterus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 61. Is an ortholog of human RUSC1 (RUN and SH3 domain containing 1) and RUSC2 (RUN and SH3 domain containing 2). WB:WBGene00006754 unc-15 Enables SH3 domain binding activity; cytoskeletal protein binding activity; and protein kinase binding activity. Involved in several processes, including positive regulation of ovulation; positive regulation of sarcomere organization; and skeletal muscle myosin thick filament assembly. Located in A band and myosin filament. Expressed in alimentary muscle; body wall musculature; gonad; vulval muscle; and in male. Is an ortholog of human MYH16 (myosin heavy chain 16 (pseudogene)). WB:WBGene00006755 unc-16 Enables kinase binding activity; kinesin binding activity; and signaling adaptor activity. Involved in several processes, including defecation; egg-laying behavior; and regulation of JNK cascade. Located in axon; cell body; and cytoplasm. Expressed in body wall musculature; hypodermis; intestine; and nervous system. Human ortholog(s) of this gene implicated in endometrial cancer; hepatocellular carcinoma; and liver cirrhosis. Is an ortholog of human MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3). WB:WBGene00006756 unc-17 Enables acetylcholine transmembrane transporter activity. Involved in several processes, including cholinergic synaptic transmission; nematode larval development; and regulation of pharyngeal pumping. Located in neuron projection; organelle membrane; and synapse. Expressed in neurons; pm2; somatic nervous system; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; and congenital myasthenic syndrome 21. Is an ortholog of human SLC18A3 (solute carrier family 18 member A3). WB:WBGene00006757 unc-18 Enables syntaxin binding activity. Involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. Located in axon. Expressed in head neurons; intestine; nervous system; uv1; and ventral cord neurons. Used to study alcohol use disorder and developmental and epileptic encephalopathy. Human ortholog(s) of this gene implicated in West syndrome; developmental and epileptic encephalopathy 4; and familial hemophagocytic lymphohistiocytosis 5. Is an ortholog of human STXBP1 (syntaxin binding protein 1). WB:WBGene00006758 unc-20 No description available WB:WBGene00006759 unc-22 Enables protein kinase binding activity and protein serine/threonine kinase activity. Involved in several processes, including adult behavior; positive regulation of sarcomere organization; and positive regulation of striated muscle contraction. Located in A band. Expressed in body wall musculature; pharyngeal muscle cell; and vulval muscle. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2J; coronary artery disease; intrinsic cardiomyopathy (multiple); and tibial muscular dystrophy. Is an ortholog of human TTN (titin). WB:WBGene00006760 unc-23 Enables ATPase activator activity and heat shock protein binding activity. Acts upstream of with a positive effect on muscle attachment. Located in M band; nucleolus; and striated muscle dense body. Expressed in several structures, including anal depressor muscle; excretory canal; pharynx; touch receptor neurons; and vulva. Is an ortholog of human BAG2 (BAG cochaperone 2). WB:WBGene00006761 unc-24 Predicted to be located in plasma membrane. Is an ortholog of human STOML1 (stomatin like 1). WB:WBGene00006762 unc-25 Predicted to enable glutamate decarboxylase activity and pyridoxal phosphate binding activity. Involved in GABAergic synaptic transmission. Located in axon; perikaryon; and synapse. Expressed in EF neuron and neurons. Used to study alcohol use disorder; epilepsy; and spastic cerebral palsy. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; developmental and epileptic encephalopathy 89; and diabetes mellitus (multiple). Is an ortholog of human GAD1 (glutamate decarboxylase 1) and GAD2 (glutamate decarboxylase 2). WB:WBGene00006763 unc-26 Predicted to enable phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Involved in several processes, including cellular component organization; nitrogen compound transport; and regulation of locomotion. Located in synapse. Expressed in tail and ventral cord neurons. Used to study Down syndrome and early-onset Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease 20 and developmental and epileptic encephalopathy 53. Is an ortholog of human SYNJ1 (synaptojanin 1). WB:WBGene00006764 unc-27 Enables troponin C binding activity. Involved in locomotion and sarcomere organization. Located in sarcomere. Expressed in body wall musculature; non-striated muscle; and rectal muscle. Human ortholog(s) of this gene implicated in several diseases, including arthrogryposis multiplex congenita; distal arthrogryposis type 2B1; and intrinsic cardiomyopathy (multiple). Is an ortholog of human TNNI1 (troponin I1, slow skeletal type); TNNI2 (troponin I2, fast skeletal type); and TNNI3 (troponin I3, cardiac type). WB:WBGene00006765 unc-29 Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in several processes, including neuromuscular synaptic transmission; positive regulation of acetylcholine secretion, neurotransmission; and regulation of multicellular organismal process. Located in neuron projection; neuronal cell body; and postsynaptic membrane. Expressed in body wall musculature; head neurons; non-striated muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; autosomal dominant nocturnal frontal lobe epilepsy 1; and congenital myasthenic syndrome (multiple). Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit); CHRNA4 (cholinergic receptor nicotinic alpha 4 subunit); and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). WB:WBGene00006766 unc-30 Enables sequence-specific DNA binding activity. Involved in neuron differentiation; positive regulation of transcription by RNA polymerase II; and regulation of locomotion. Located in nucleus. Expressed in GABAergic neurons; ganglia; intestine; and ventral cord neurons. Human ortholog(s) of this gene implicated in Arts syndrome; clubfoot; and eye disease (multiple). Is an ortholog of human PITX2 (paired like homeodomain 2) and PITX3 (paired like homeodomain 3). WB:WBGene00006767 unc-31 Predicted to enable calcium ion binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including cellular response to carbon dioxide; regulation of multicellular organismal process; and signal release. Located in several cellular components, including axon; dense core granule; and neuronal cell body. Expressed in several structures, including CAN; egg-laying apparatus; excretory gland cell; rectal gland cell; and spermatheca. Is an ortholog of human CADPS2 (calcium dependent secretion activator 2). WB:WBGene00006768 unc-32 Predicted to enable ATPase binding activity. Involved in several processes, including cholinergic synaptic transmission; defense response to Gram-positive bacterium; and positive regulation of neurotransmitter secretion. Part of vacuolar proton-transporting V-type ATPase complex. Expressed in several structures, including alimentary muscle; hermaphrodite gonad; neurons; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive cutis laxa type IIA; autosomal recessive osteopetrosis 1; and developmental and epileptic encephalopathy 104. Is an ortholog of human ATP6V0A1 (ATPase H+ transporting V0 subunit a1). WB:WBGene00006769 unc-33 Enables filamin binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in several processes, including axon guidance; establishment or maintenance of cytoskeleton polarity; and regulation of locomotion. Located in neuron projection. Expressed in amphid socket cell; neuroblasts; neurons; pharyngeal cell; and somatic nervous system. Is an ortholog of human DPYSL2 (dihydropyrimidinase like 2). WB:WBGene00006770 unc-34 Enables signaling receptor binding activity. Involved in axon development; gonad morphogenesis; and positive regulation of locomotion. Located in several cellular components, including cell junction; cell leading edge; and filopodium tip. Expressed in epithelial cell. Used to study tauopathy. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human ENAH (ENAH actin regulator) and EVL (Enah/Vasp-like). WB:WBGene00006771 tln-1 Predicted to enable integrin binding activity. Involved in negative regulation of epidermal growth factor receptor signaling pathway; regulation of vulval development; and vulval cell fate specification. Located in basement membrane; contractile fiber; and lateral plasma membrane. Expressed in several structures, including Psub4; Z2; Z3; distal tip cell; and vulval cell. Is an ortholog of human TLN2 (talin 2). WB:WBGene00006772 unc-36 Enables calcium channel regulator activity and voltage-gated calcium channel activity. Involved in several processes, including egg-laying behavior; pharyngeal pumping; and serotonin receptor signaling pathway. Located in endoplasmic reticulum membrane and plasma membrane. Part of voltage-gated calcium channel complex. Expressed in head muscle; neurons; non-striated muscle; and ventral nerve cord. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 110 and retinal cone dystrophy 4. Is an ortholog of human CACNA2D3 (calcium voltage-gated channel auxiliary subunit alpha2delta 3). WB:WBGene00006773 unc-37 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription corepressor activity. Involved in several processes, including chemical synaptic transmission; regulation of axonogenesis; and regulation of synapse structure or activity. Located in nucleus. Expressed in several structures, including germ line; head; and tail. Is an ortholog of human TLE2 (TLE family member 2, transcriptional corepressor). WB:WBGene00006774 unc-38 Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in several processes, including calcium ion import across plasma membrane; neuromuscular synaptic transmission; and regulation of multicellular organismal process. Located in neuron projection and postsynaptic membrane. Expressed in several structures, including body wall musculature; copulatory spicule; enteric muscle; oblique male muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autosomal dominant nocturnal frontal lobe epilepsy (multiple); congenital myasthenic syndrome (multiple); and lung disease (multiple). Is an ortholog of human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit) and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). WB:WBGene00006775 unc-39 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; generation of neurons; and regulation of locomotion. Located in nucleus. Expressed in several structures, including AIA; IL2 neuron; RID; coelomocyte; and neuroblasts. Used to study branchiootorenal syndrome and myotonic dystrophy type 1. Human ortholog(s) of this gene implicated in branchiootorenal syndrome 2. Is an ortholog of human SIX4 (SIX homeobox 4) and SIX5 (SIX homeobox 5). WB:WBGene00006776 unc-40 Enables netrin receptor activity and protein domain specific binding activity. Involved in several processes, including axon guidance; regulation of locomotion; and sex differentiation. Acts upstream of or within dendrite morphogenesis and distal tip cell migration. Located in axonal growth cone and cell projection membrane. Part of receptor complex. Expressed in several structures, including hermaphrodite somatic gonadal cell; motor neurons; neuroblasts; somatic nervous system; and touch receptor neurons. Human ortholog(s) of this gene implicated in colorectal cancer; congenital mirror movement disorder; and esophagus squamous cell carcinoma. Is an ortholog of human DCC (DCC netrin 1 receptor) and NEO1 (neogenin 1). WB:WBGene00006777 unc-41 Predicted to enable clathrin adaptor activity. Involved in positive regulation of locomotion. Located in synapse. Expressed in DD neuron; VD neuron; and cholinergic neurons. Is an ortholog of human STON2 (stonin 2). WB:WBGene00006778 unc-42 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including larval locomotory behavior; neuron differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in hypodermis; nerve ring; and neurons. Human ortholog(s) of this gene implicated in hypogonadism and panhypopituitarism. Is an ortholog of several human genes including ESX1 (ESX homeobox 1); PROP1 (PROP paired-like homeobox 1); and RHOXF2 (Rhox homeobox family member 2). WB:WBGene00006779 unc-43 Enables identical protein binding activity; protein serine/threonine kinase activity; and transmembrane transporter binding activity. Involved in MAPK cascade; medium-term memory; and positive regulation of gene expression. Acts upstream of or within serotonin biosynthetic process. Located in axon cytoplasm. Expressed in several structures, including AWC; copulatory spicule; gonadal sheath cell; oocyte; and somatic nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; intellectual disability (multiple); and malignant astrocytoma. Is an ortholog of human CAMK2D (calcium/calmodulin dependent protein kinase II delta). WB:WBGene00006780 unc-44 Enables cell adhesion molecule binding activity. Involved in several processes, including axon guidance; establishment or maintenance of cytoskeleton polarity; and regulation of cellular component organization. Located in lateral plasma membrane. Expressed in hermaphrodite gonad; hypodermis; intestinal cell; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including ankyrin-B-related cardiac arrhythmia; autosomal recessive intellectual developmental disorder 37; and heart conduction disease (multiple). Is an ortholog of human ANK2 (ankyrin 2) and ANK3 (ankyrin 3). WB:WBGene00006781 unc-45 Enables identical protein binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including egg-laying behavior; embryo development; and sarcomere organization. Located in cell cortex and cleavage furrow. Expressed in body wall musculature and non-striated muscle. Human ortholog(s) of this gene implicated in cataract 43 and myofibrillar myopathy 11. Is an ortholog of human UNC45B (unc-45 myosin chaperone B). WB:WBGene00006782 unc-46 Located in cytoplasmic vesicle and neuromuscular junction. Expressed in GLR and neurons. WB:WBGene00006783 unc-47 Predicted to enable glycine transmembrane transporter activity. Predicted to be involved in gamma-aminobutyric acid transport; glycine transport; and neurotransmitter loading into synaptic vesicle. Located in synaptic vesicle. Expressed in neurons. Used to study alcohol use disorder. Is an ortholog of human SLC32A1 (solute carrier family 32 member 1). WB:WBGene00006784 unc-49 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Involved in gamma-aminobutyric acid signaling pathway; locomotory behavior; and regulation of backward locomotion. Located in neuromuscular junction and postsynaptic membrane. Expressed in AVA; anal sphincter muscle; body wall musculature; and somatic nervous system. Used to study epilepsy. WB:WBGene00006785 unc-50 Involved in receptor localization to synapse and regulation of muscle contraction. Located in Golgi membrane. Expressed in several structures, including alimentary muscle; gonad; intestine; neurons; and vulval muscle. Is an ortholog of human UNC50 (unc-50 inner nuclear membrane RNA binding protein). WB:WBGene00006786 unc-51 Enables protein serine/threonine kinase activity. Involved in several processes, including determination of adult lifespan; nematode male tail tip morphogenesis; and regulation of axon extension. Located in axon and neuronal cell body. Expressed in body wall musculature; motor neurons; pharyngeal muscle cell; and touch receptor neurons. Is an ortholog of human ULK1 (unc-51 like autophagy activating kinase 1) and ULK2 (unc-51 like autophagy activating kinase 2). WB:WBGene00006787 unc-52 An extracellular matrix structural constituent. Involved in several processes, including hemidesmosome assembly; muscle cell cellular homeostasis; and muscle structure development. Located in basement membrane and striated muscle dense body. Expressed in alimentary muscle; body wall musculature; gonad; and pharyngeal-intestinal valve. Human ortholog(s) of this gene implicated in several diseases, including Schwartz-Jampel syndrome 1; Silverman-Handmaker type dyssegmental dysplasia; and hyperglycemia. Is an ortholog of human HSPG2 (heparan sulfate proteoglycan 2). WB:WBGene00006788 unc-53 Predicted to enable actin filament binding activity. Involved in several processes, including backward locomotion; positive regulation of locomotion; and reproductive behavior. Located in cytoplasm. Expressed in several structures, including excretory cell; hermaphrodite distal tip cell; neurons; non-striated muscle; and socket cell. Is an ortholog of human NAV1 (neuron navigator 1). WB:WBGene00006789 unc-54 Enables actin filament binding activity and microfilament motor activity. A structural constituent of muscle. Involved in several processes, including egg-laying behavior; muscle contraction; and skeletal muscle myosin thick filament assembly. Located in A band and striated muscle myosin thick filament. Part of muscle myosin complex. Expressed in anal depressor muscle; body wall musculature; head; vulval muscle; and in male. Human ortholog(s) of this gene implicated in several diseases, including congenital heart disease (multiple); distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3). WB:WBGene00006790 unc-55 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in cell fate specification and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in motor neurons; somatic nervous system; and spicule muscle. Human ortholog(s) of this gene implicated in 46,XX sex reversal 5 and Bosch-Boonstra-Schaaf optic atrophy syndrome. Is an ortholog of human NR2F1 (nuclear receptor subfamily 2 group F member 1) and NR2F2 (nuclear receptor subfamily 2 group F member 2). WB:WBGene00006791 unc-57 Involved in clathrin-dependent endocytosis and necroptotic process. Located in neuromuscular junction. Expressed in several structures, including coelomocyte; head; hermaphrodite gonad; intestine; and muscle cell. Human ortholog(s) of this gene implicated in acute myeloid leukemia and high grade glioma. Is an ortholog of human SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2); SH3GL2 (SH3 domain containing GRB2 like 2, endophilin A1); and SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3). WB:WBGene00006792 unc-58 Enables outward rectifier potassium channel activity. Involved in several processes, including muscle contraction; parturition; and regulation of muscle contraction. Predicted to be located in membrane. Expressed in interneuron and motor neurons. Is an ortholog of human KCNK17 (potassium two pore domain channel subfamily K member 17) and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00006793 unc-59 Predicted to enable GTPase activity and molecular adaptor activity. Involved in egg-laying behavior; locomotion; and post-embryonic development. Located in cleavage furrow and midbody. Expressed in several structures, including buccal cavity; distal tip cell; germ line; pharynx; and sperm. Human ortholog(s) of this gene implicated in Lewy body dementia and Parkinson's disease. Is an ortholog of human SEPTIN7 (septin 7). WB:WBGene00006794 unc-60 Enables actin filament binding activity. Involved in several processes, including actin filament-based process; embryo development; and positive regulation of actin filament polymerization. Located in striated muscle thin filament. Part of ribonucleoprotein complex. Expressed in several structures, including germ line; hermaphrodite gonad; nerve ring; oocyte; and vulva. Human ortholog(s) of this gene implicated in brain compression; gallbladder carcinoma; and nemaline myopathy 7. Is an ortholog of human CFL2 (cofilin 2). WB:WBGene00006795 unc-61 Predicted to enable GTPase activity and molecular adaptor activity. Predicted to be involved in cytoskeleton-dependent cytokinesis. Located in cleavage furrow and midbody. Expressed in anterior distal tip cell; nerve ring; posterior distal tip cell; and ventral cord neurons. Human ortholog(s) of this gene implicated in Parkinson's disease. Is an ortholog of human SEPTIN11 (septin 11) and SEPTIN8 (septin 8). WB:WBGene00006796 unc-62 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cell fate specification; muscle cell differentiation; and regulation of macromolecule biosynthetic process. Acts upstream of or within lipid homeostasis. Located in nucleus. Part of chromatin. Expressed in several structures, including body wall musculature; neurons; reproductive system; ventral nerve cord; and vulval precursor cell. Used to study leukemia and restless legs syndrome. Human ortholog(s) of this gene implicated in several diseases, including cleft palate; cleft palate, cardiac defects, and intellectual disabillity; and open-angle glaucoma. Is an ortholog of human MEIS1 (Meis homeobox 1). WB:WBGene00006797 unc-63 Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in several processes, including calcium ion import across plasma membrane; cholinergic synaptic transmission; and regulation of multicellular organismal process. Located in neuromuscular junction and postsynaptic membrane. Expressed in ganglia; head muscle; motor neurons; non-striated muscle; and ventral nerve cord. Used to study alcohol use disorder and congenital myasthenic syndrome. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autosomal dominant nocturnal frontal lobe epilepsy (multiple); congenital myasthenic syndrome (multiple); and lung disease (multiple). Is an ortholog of human CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit); CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit); and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). WB:WBGene00006798 unc-64 Enables protein-folding chaperone binding activity. Involved in several processes, including chemical synaptic transmission; positive regulation of anterior/posterior axon guidance; and ventral cord development. Located in axon; basolateral plasma membrane; and somatodendritic compartment. Expressed in several structures, including excretory gland cell; hermaphrodite gonad; intestine; nervous system; and rectal gland cell. Human ortholog(s) of this gene implicated in several diseases, including Creutzfeldt-Jakob disease; Hirschsprung's disease; and generalized epilepsy with febrile seizures plus 9. Is an ortholog of human STX1A (syntaxin 1A). WB:WBGene00006799 unc-65 Acts upstream of or within cholinergic synaptic transmission. WB:WBGene00006801 unc-68 Predicted to enable calcium ion binding activity and ryanodine-sensitive calcium-release channel activity. Involved in locomotion; positive regulation of programmed cell death; and protein localization to organelle. Located in I band and sarcoplasmic reticulum. Expressed in body wall musculature; intestine; neurons; and non-striated muscle. Used to study congenital myopathy 1A and malignant hyperthermia. Human ortholog(s) of this gene implicated in several diseases, including catecholaminergic polymorphic ventricular tachycardia 1; intracranial vasospasm; and muscle tissue disease (multiple). Is an ortholog of human RYR1 (ryanodine receptor 1); RYR2 (ryanodine receptor 2); and RYR3 (ryanodine receptor 3). WB:WBGene00006802 unc-69 Involved in regulation of axon extension and regulation of synapse organization. Located in axon; neuronal cell body; and perinuclear region of cytoplasm. Expressed in CAN; HSN; ganglia; somatic nervous system; and touch receptor neurons. Is an ortholog of human SCOC (short coiled-coil protein). WB:WBGene00006803 unc-70 Predicted to enable actin filament binding activity. Involved in several processes, including dendrite development; embryonic body morphogenesis; and muscle cell cellular homeostasis. Located in cell junction; contractile fiber; and lateral plasma membrane. Expressed in hermaphrodite gonad and vulval cell. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 14; hereditary spherocytosis type 2; and spinocerebellar ataxia type 5. Is an ortholog of human SPTB (spectrin beta, erythrocytic). WB:WBGene00006804 unc-71 Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Located in membrane. Expressed in several structures, including buccal cavity; excretory system; nerve ring; neuronal sheath cell; and neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 61. Is an ortholog of human ADAM22 (ADAM metallopeptidase domain 22) and ADAM23 (ADAM metallopeptidase domain 23). WB:WBGene00006805 unc-73 Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in several processes, including cellular component organization; modulation of chemical synaptic transmission; and positive regulation of protein localization to synapse. Located in axon; cytoplasm; and muscle cell projection. Expressed in several structures, including egg-laying apparatus; hermaphrodite gonad; lumbar ganglion; neurons; and tail hypodermis. Used to study epilepsy. Human ortholog(s) of this gene implicated in artery disease (multiple); autosomal dominant intellectual developmental disorder 44; and cerebral infarction. Is an ortholog of human KALRN (kalirin RhoGEF kinase) and TRIO (trio Rho guanine nucleotide exchange factor). WB:WBGene00006806 unc-74 Acts upstream of or within egg-laying behavior. WB:WBGene00006807 unc-75 Enables single-stranded RNA binding activity. Involved in several processes, including cholinergic synaptic transmission; positive regulation of synaptic transmission; and regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck. Expressed in neurons and pharyngeal gland cell. Is an ortholog of human CELF5 (CUGBP Elav-like family member 5) and CELF6 (CUGBP Elav-like family member 6). WB:WBGene00006808 unc-76 Enables syntaxin binding activity. Involved in anterograde axonal protein transport; axonal fasciculation; and regulation of cellular component organization. Located in axon; neuronal cell body; and perinuclear region of cytoplasm. Expressed in neurons and somatic nervous system. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human FEZ1 (fasciculation and elongation protein zeta 1). WB:WBGene00006809 unc-77 Enables monoatomic cation channel activity. Involved in positive regulation of GABAergic synaptic transmission; positive regulation of cholinergic synaptic transmission; and positive regulation of locomotion. Located in axon. Expressed in cholinergic neurons; nerve ring; pharyngeal neurons; and tail ganglion. Used to study congenital limbs-face contractures-hypotonia-developmental delay syndrome. Human ortholog(s) of this gene implicated in congenital limbs-face contractures-hypotonia-developmental delay syndrome. Is an ortholog of human NALCN (sodium leak channel, non-selective). WB:WBGene00006810 unc-78 Enables actin filament binding activity. Involved in several processes, including myofibril assembly; regulation of actin polymerization or depolymerization; and regulation of locomotion. Located in myofibril and sarcoplasm. Expressed in body wall musculature; pharynx; spermatheca; uterus; and vulva. Is an ortholog of human WDR1 (WD repeat domain 1). WB:WBGene00006811 unc-79 Involved in several processes, including response to anesthetic; response to ethanol; and response to toluene. Located in axon. Expressed in head neurons; nerve ring; nervous system; tail neurons; and ventral cord neurons. Used to study alcohol use disorder. Is an ortholog of human UNC79 (unc-79 homolog, NALCN channel complex subunit). WB:WBGene00006812 unc-80 Enables monoatomic cation channel activity. Involved in several processes, including monoatomic cation homeostasis; positive regulation of locomotion; and response to anesthetic. Located in axon. Part of cation channel complex. Expressed in excretory canal; hermaphrodite distal tip cell; nervous system; and non-striated muscle. Is an ortholog of human UNC80 (unc-80 homolog, NALCN channel complex subunit). WB:WBGene00006814 unc-82 A structural constituent of muscle. Involved in striated muscle myosin thick filament assembly and striated muscle paramyosin thick filament assembly. Located in M band. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in anencephaly. Is an ortholog of human NUAK1 (NUAK family kinase 1) and NUAK2 (NUAK family kinase 2). WB:WBGene00006815 unc-83 Enables dynein light chain binding activity. Involved in several processes, including cellular localization; egg-laying behavior; and vulval development. Located in nuclear outer membrane. Expressed in several structures, including P1; P12; P2; P3; and P9. Used to study Emery-Dreifuss muscular dystrophy. WB:WBGene00006816 unc-84 Enables lamin binding activity. Involved in several processes, including egg-laying behavior; nuclear migration along microtubule; and vulval development. Located in nuclear inner membrane. Expressed in several structures, including oocyte. Human ortholog(s) of this gene implicated in spermatogenic failure 16. Is an ortholog of human SUN2 (Sad1 and UNC84 domain containing 2) and SUN3 (Sad1 and UNC84 domain containing 3). WB:WBGene00006817 unc-85 Predicted to enable histone binding activity. Involved in egg-laying behavior and post-embryonic development. Located in nucleus. Expressed in several structures, including germ line. Is an ortholog of human ASF1A (anti-silencing function 1A histone chaperone). WB:WBGene00006818 unc-86 Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in mechanosensory behavior; neuron differentiation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in neurons. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 15. Is an ortholog of human POU4F1 (POU class 4 homeobox 1); POU4F2 (POU class 4 homeobox 2); and POU4F3 (POU class 4 homeobox 3). WB:WBGene00006819 unc-87 Enables actin filament binding activity; cytoskeletal motor inhibitor activity; and myosin binding activity. Involved in actin cytoskeleton organization and negative regulation of muscle filament sliding. Located in I band; stress fiber; and striated muscle thin filament. Part of actomyosin, myosin complex part. Expressed in several structures, including non-striated muscle; pharynx; spermatheca; ventral ganglion; and vulva. WB:WBGene00006820 unc-89 Enables MATH domain binding activity; enzyme binding activity; and guanyl-nucleotide exchange factor activity. Involved in several processes, including myofibril assembly; pharyngeal gland morphogenesis; and regulation of striated muscle contraction. Located in M band. Expressed in alimentary muscle; gonad; tail; and vulval muscle. Human ortholog(s) of this gene implicated in centronuclear myopathy 5. Is an ortholog of human SPEG (striated muscle enriched protein kinase). WB:WBGene00006821 unc-90 No description available WB:WBGene00006822 unc-93 Enables potassium channel regulator activity. Involved in regulation of muscle contraction and regulation of potassium ion transport. Located in plasma membrane and striated muscle dense body. Expressed in SIA; body wall musculature; and non-striated muscle. Is an ortholog of human UNC93A (unc-93 homolog A). WB:WBGene00006823 unc-94 Predicted to enable tropomyosin binding activity. Involved in several processes, including myofibril assembly; nematode larval development; and pointed-end actin filament capping. Located in striated muscle thin filament and terminal web. Expressed in intestine; pharyngeal muscle cell; seam cell; spermatheca; and uterine muscle. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2G; megacystis-microcolon-intestinal hypoperistalsis syndrome; and nemaline myopathy 10. Is an ortholog of several human genes including TMOD1 (tropomodulin 1); TMOD3 (tropomodulin 3); and TMOD4 (tropomodulin 4). WB:WBGene00006824 unc-95 Enables protein domain specific binding activity. Located in M band; nucleus; and striated muscle dense body. WB:WBGene00006825 unc-96 Enables myosin binding activity. Involved in locomotion; regulation of cytoskeleton organization; and striated muscle myosin thick filament assembly. Located in M band and striated muscle myosin thick filament. Expressed in anal depressor muscle; body wall musculature; and pharyngeal muscle cell. WB:WBGene00006826 unc-97 Enables myosin binding activity. Involved in several processes, including muscle cell cellular homeostasis; positive regulation of sarcomere organization; and sensory perception of mechanical stimulus. Located in several cellular components, including adherens junction; basal plasma membrane; and contractile fiber. Expressed in body wall musculature and vulval muscle. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2W. Is an ortholog of human LIMS1 (LIM zinc finger domain containing 1) and LIMS2 (LIM zinc finger domain containing 2). WB:WBGene00006827 unc-98 Enables cytoskeletal protein binding activity. Involved in several processes, including locomotory behavior; myofibril assembly; and post-embryonic body morphogenesis. Located in M band and nucleus. Expressed in anal depressor muscle; body wall musculature; head muscle; and vulval muscle. WB:WBGene00006828 unc-100 No description available WB:WBGene00006829 unc-101 Predicted to enable clathrin adaptor activity. Involved in several processes, including cilium assembly; nematode larval development; and protein localization. Predicted to be located in clathrin-coated vesicle. Predicted to be part of clathrin adaptor complex. Expressed in several structures, including germ line; head; and tail. Is an ortholog of human AP1M1 (adaptor related protein complex 1 subunit mu 1). WB:WBGene00006830 unc-103 Predicted to enable inward rectifier potassium channel activity. Involved in mating behavior and regulation of muscle contraction. Predicted to be located in plasma membrane. Expressed in body wall musculature; neurons; non-striated muscle; and in male. Used to study long QT syndrome. Human ortholog(s) of this gene implicated in long QT syndrome 2 and short QT syndrome. Is an ortholog of human KCNH2 (potassium voltage-gated channel subfamily H member 2) and KCNH7 (potassium voltage-gated channel subfamily H member 7). WB:WBGene00006831 unc-104 Enables cytoskeletal protein binding activity; phosphatidylinositol phosphate binding activity; and plus-end-directed microtubule motor activity. Involved in several processes, including chemical synaptic transmission; regulation of cellular component organization; and regulation of cellular localization. Located in axon; presynapse; and somatodendritic compartment. Expressed in epithelial cell; muscle cell; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and neuropathy (multiple). Is an ortholog of human KIF1A (kinesin family member 1A). WB:WBGene00006832 unc-105 Enables monoatomic ion channel activity. Involved in calcium ion transport; magnesium ion transport; and muscle organ development. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in bronchiectasis (multiple) and renal tubular transport disease (multiple). Is an ortholog of human SCNN1B (sodium channel epithelial 1 subunit beta); SCNN1D (sodium channel epithelial 1 subunit delta); and SCNN1G (sodium channel epithelial 1 subunit gamma). WB:WBGene00006833 unc-108 Enables GTPase activity. Involved in several processes, including dense core granule maturation; phagosome maturation involved in apoptotic cell clearance; and regulation of locomotion involved in locomotory behavior. Located in axon; cytoplasm; and neuronal cell body. Expressed in several structures, including excretory gland cell; hermaphrodite somatic gonadal cell; neurons; pharyngeal gland cell; and rectal gland cell. Is an ortholog of human RAB2A (RAB2A, member RAS oncogene family). WB:WBGene00006835 unc-111 No description available WB:WBGene00006836 unc-112 Enables integrin binding activity; protein self-association; and protein-macromolecule adaptor activity. Involved in several processes, including muscle cell cellular homeostasis; positive regulation of supramolecular fiber organization; and regulation of engulfment of apoptotic cell. Located in cell-substrate junction; contractile fiber; and plasma membrane. Expressed in body wall musculature; non-striated muscle; and spermatheca. Used to study Kindler syndrome. Human ortholog(s) of this gene implicated in several diseases, including Kindler syndrome; leukocyte adhesion deficiency (multiple); and telangiectasis. Is an ortholog of human FERMT1 (FERM domain containing kindlin 1) and FERMT2 (FERM domain containing kindlin 2). WB:WBGene00006837 unc-113 No description available WB:WBGene00006838 unc-114 No description available WB:WBGene00006839 unc-115 Enables actin filament binding activity. Involved in neuron projection morphogenesis; regulation of filopodium assembly; and regulation of lamellipodium assembly. Located in basal plasma membrane and cytoplasm. Expressed in several structures, including PDE; excretory cell; pharynx; somatic nervous system; and vulva. Is an ortholog of human ABLIM2 (actin binding LIM protein family member 2). WB:WBGene00006840 unc-116 Enables plus-end-directed microtubule motor activity. Involved in several processes, including establishment of organelle localization; organelle organization; and positive regulation of cell projection organization. Located in several cellular components, including neuron projection; nuclear envelope; and synapse. Part of kinesin I complex. Expressed in several structures, including AVA; body ganglion; muscle cell; tail; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 3; asbestos-related lung carcinoma; autoimmune disease (multiple); and complex cortical dysplasia with other brain malformations 2. Is an ortholog of human KIF5A (kinesin family member 5A); KIF5B (kinesin family member 5B); and KIF5C (kinesin family member 5C). WB:WBGene00006841 unc-117 No description available WB:WBGene00006842 unc-118 No description available WB:WBGene00006843 unc-119 Predicted to enable lipid binding activity. Involved in several processes, including body morphogenesis; dauer larval development; and regulation of multicellular organismal process. Located in axon. Expressed in several structures, including body wall musculature; ganglia; neurons; seam cell; and somatic nervous system. Human ortholog(s) of this gene implicated in cone-rod dystrophy and immunodeficiency 13. Is an ortholog of human UNC119 (unc-119 lipid binding chaperone) and UNC119B (unc-119 lipid binding chaperone B). WB:WBGene00006844 unc-120 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within positive regulation of muscle cell differentiation. Located in nucleus. Expressed in non-striated muscle and pharyngeal cell. Human ortholog(s) of this gene implicated in cardiomyopathy; congestive heart failure; and lymphangioleiomyomatosis. Is an ortholog of human SRF (serum response factor). WB:WBGene00006845 unc-122 Involved in negative regulation of cholinergic synaptic transmission. Located in postsynaptic membrane. Expressed in body wall musculature and coelomocyte. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Is an ortholog of human GLDN (gliomedin) and OLFML2B (olfactomedin like 2B). WB:WBGene00006846 unc-123 No description available WB:WBGene00006848 unc-125 No description available WB:WBGene00006849 unc-126 No description available WB:WBGene00006850 unc-127 No description available WB:WBGene00006851 unc-128 No description available WB:WBGene00006852 unc-129 Enables signaling receptor binding activity. Involved in several processes, including axon guidance; backward locomotion; and inductive cell migration. Predicted to be located in extracellular space. Expressed in several structures, including CAN; PDE socket cell; body wall musculature; cholinergic neurons; and terminal bulb. Is an ortholog of human GDF10 (growth differentiation factor 10). WB:WBGene00006853 unc-130 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and transcription corepressor activity. Involved in several processes, including axon extension involved in axon guidance; negative regulation of transcription by RNA polymerase II; and nematode male tail tip morphogenesis. Located in nucleus. Expressed in several structures, including HO neuron; hypodermis; ray; tail; and ventral body wall muscle. Human ortholog(s) of this gene implicated in glaucoma and vitiligo. Is an ortholog of several human genes including FOXD3 (forkhead box D3); FOXD4 (forkhead box D4); and FOXD4L1 (forkhead box D4 like 1). WB:WBGene00006854 unc-131 No description available WB:WBGene00006856 usp-14 Predicted to enable cysteine-type deubiquitinase activity and proteasome binding activity. Predicted to be involved in regulation of proteasomal protein catabolic process. Predicted to be part of proteasome complex. Is an ortholog of human USP14 (ubiquitin specific peptidase 14). WB:WBGene00006857 uts-1 No description available WB:WBGene00006858 uts-2 No description available WB:WBGene00006859 uts-3 No description available WB:WBGene00006860 uts-4 No description available WB:WBGene00006861 cal-5 Predicted to enable calcium ion binding activity. WB:WBGene00006862 pnk-4 Predicted to enable pantothenate kinase activity. Predicted to be involved in coenzyme A biosynthetic process. Predicted to be located in cytosol and nucleus. Expressed in tail. Human ortholog(s) of this gene implicated in cataract. Is an ortholog of human PANK4 (pantothenate kinase 4 (inactive)). WB:WBGene00006863 gyg-1 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycogen biosynthetic process. Located in striated muscle dense body. Expressed in hypodermis. Is an ortholog of human GYG2 (glycogenin 2). WB:WBGene00006864 npr-16 Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection. Expressed in anal depressor muscle; neurons; ventral nerve cord; and vm1. Is an ortholog of human SSTR3 (somatostatin receptor 3). WB:WBGene00006865 slcf-2 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. Is an ortholog of several human genes including SLC2A11 (solute carrier family 2 member 11); SLC2A5 (solute carrier family 2 member 5); and SLC2A9 (solute carrier family 2 member 9). WB:WBGene00006866 uxt-1 No description available WB:WBGene00006867 uxt-2 No description available WB:WBGene00006868 vab-1 Enables ephrin receptor activity and protein domain specific binding activity. Involved in several processes, including cell development; embryonic morphogenesis; and regulation of axon guidance. Located in axon and plasma membrane. Expressed in several structures, including hypodermal cell; neuroblasts; neurons; oocyte; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; aortic dissection; cataract 6 multiple types; and gastrointestinal system cancer (multiple). Is an ortholog of several human genes including EPHB1 (EPH receptor B1); EPHB2 (EPH receptor B2); and EPHB3 (EPH receptor B3). WB:WBGene00006869 vab-2 Enables ephrin receptor binding activity. Involved in ephrin receptor signaling pathway and epidermis morphogenesis. Located in axon and external side of plasma membrane. Expressed in several structures, including anterior ganglion; neuroblasts; neurons; somatic nervous system; and ventral ganglion (post). Human ortholog(s) of this gene implicated in craniofrontonasal syndrome; dysostosis; and stomach cancer. Is an ortholog of human EFNB1 (ephrin B1). WB:WBGene00006870 vab-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including male anatomical structure morphogenesis; negative regulation of distal tip cell migration; and positive regulation of glial cell differentiation. Located in cytoplasm and nucleus. Expressed in several structures, including Y.p; distal tip cell; head muscle; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including bilateral optic nerve hypoplasia; eye disease (multiple); and glucose intolerance. Is an ortholog of human PAX6 (paired box 6). WB:WBGene00006871 vab-5 No description available WB:WBGene00006872 vab-6 No description available WB:WBGene00006873 vab-7 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cell fate specification and negative regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in muscle cell; neurons; somatic nervous system; and tail hypodermis. Is an ortholog of human EVX1 (even-skipped homeobox 1) and EVX2 (even-skipped homeobox 2). WB:WBGene00006874 vab-8 Predicted to enable ATP binding activity; microtubule binding activity; and microtubule motor activity. Involved in several processes, including egg-laying behavior; generation of neurons; and negative regulation of motor neuron migration. Located in striated muscle thin filament. Expressed in body wall musculature and neurons. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Is an ortholog of human KIF26A (kinesin family member 26A) and KIF26B (kinesin family member 26B). WB:WBGene00006875 vab-9 Involved in cell-cell adhesion; defense response to Gram-negative bacterium; and innate immune response. Located in cell junction. Expressed in epithelial cell; hypodermis; and nerve ring. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and mutilating palmoplantar keratoderma with periorificial keratotic plaques. Is an ortholog of human TMEM47 (transmembrane protein 47). WB:WBGene00006876 vab-10 Predicted to enable actin filament binding activity and structural molecule activity. Involved in epidermis morphogenesis. Located in apical plasma membrane; basal plasma membrane; and hemidesmosome. Expressed in several structures, including gonad; intestinal lumen; nerve ring; pharynx; and vulval cell. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex; hereditary sensory and autonomic neuropathy type 6; and lissencephaly 9 with complex brainstem malformation. Is an ortholog of human DST (dystonin). WB:WBGene00006877 vab-11 No description available WB:WBGene00006878 vab-12 No description available WB:WBGene00006880 vab-14 No description available WB:WBGene00006881 vab-15 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in embryonic morphogenesis; locomotory behavior; and parturition. Located in nucleus. Expressed in several structures, including P1; P12; P2; neuroblasts; and neurons. Human ortholog(s) of this gene implicated in several diseases, including cleft lip; orofacial cleft 5; and tooth disease (multiple). Is an ortholog of human MSX1 (msh homeobox 1). WB:WBGene00006882 vab-19 Involved in several processes, including actin cytoskeleton organization; cell-cell junction maintenance; and embryo development. Located in cell-cell junction; hemidesmosome; and intermediate filament. Expressed in hypodermis; marginal cell; uterus; and vulD. Used to study cancer. Human ortholog(s) of this gene implicated in nephrotic syndrome type 16; renal cell carcinoma; and spastic quadriplegic cerebral palsy 2. Is an ortholog of human KANK2 (KN motif and ankyrin repeat domains 2). WB:WBGene00006883 vab-22 No description available WB:WBGene00006884 vac-1 No description available WB:WBGene00006885 vac-2 No description available WB:WBGene00006886 vap-1 Predicted to be located in extracellular space. Expressed in amphid sheath cell. WB:WBGene00006887 vav-1 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in several processes, including negative regulation of Notch signaling pathway; positive regulation of nematode male tail tip morphogenesis; and regulation of vulval development. Predicted to be located in cytoplasm. Expressed in several structures, including gonad; intestinal cell; neurons; pharyngeal cell; and tail hypodermis. Is an ortholog of human VAV1 (vav guanine nucleotide exchange factor 1); VAV2 (vav guanine nucleotide exchange factor 2); and VAV3 (vav guanine nucleotide exchange factor 3). WB:WBGene00006888 vbh-1 Predicted to enable RNA binding activity and RNA helicase activity. Involved in developmental process involved in reproduction; positive regulation of embryonic development; and positive regulation of fertilization. Located in P granule and cytoplasmic stress granule. Expressed in several structures, including Z2; Z3; germ cell; somatic cell; and in male. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and syndromic X-linked intellectual disability. Is an ortholog of human DDX3X (DEAD-box helicase 3 X-linked). WB:WBGene00006889 pfd-3 Predicted to enable tubulin binding activity. Predicted to be involved in microtubule-based process and tubulin complex assembly. Located in cytoplasm. Expressed in body wall musculature; head muscle; oocyte; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human VBP1 (VHL binding protein 1). WB:WBGene00006890 vem-1 Involved in innate immune response. Located in axon. Expressed in AVG; head neurons; and somatic nervous system. Is an ortholog of human PGRMC1 (progesterone receptor membrane component 1). WB:WBGene00006891 ven-1 No description available WB:WBGene00006892 ven-2 No description available WB:WBGene00006893 spon-1 Predicted to enable metal ion binding activity and serine-type endopeptidase inhibitor activity. Involved in axon development; cell adhesion mediated by integrin; and muscle attachment. Located in M band; basement membrane; and striated muscle dense body. Expressed in basal lamina; coelomocyte; excretory canal; and pharynx. Is an ortholog of human SPON1 (spondin 1). WB:WBGene00006894 ver-1 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in nematode male tail tip morphogenesis. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in intestinal muscle; intestine; and neuronal sheath cell. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); eye disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including FLT1 (fms related receptor tyrosine kinase 1); FLT3 (fms related receptor tyrosine kinase 3); and FLT4 (fms related receptor tyrosine kinase 4). WB:WBGene00006895 ver-2 Expressed in ADLL and ADLR. WB:WBGene00006896 ver-3 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in nematode male tail tip morphogenesis. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in ALA; anal sphincter muscle; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including cerebrovascular disease (multiple); kidney cancer (multiple); and retinal disease (multiple). Is an ortholog of human FLT1 (fms related receptor tyrosine kinase 1). WB:WBGene00006897 ver-4 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in nematode male tail tip morphogenesis. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); eye disease (multiple); and reproductive organ cancer (multiple). Is an ortholog of human FLT1 (fms related receptor tyrosine kinase 1); FLT4 (fms related receptor tyrosine kinase 4); and KDR (kinase insert domain receptor). WB:WBGene00006901 vet-5 No description available WB:WBGene00006902 vet-6 Involved in gastrulation. Located in cytoplasm. WB:WBGene00006903 vet-7 No description available WB:WBGene00006904 vet-8 No description available WB:WBGene00006905 vet-9 No description available WB:WBGene00006906 vet-10 No description available WB:WBGene00006907 vet-11 No description available WB:WBGene00006908 vex-1 No description available WB:WBGene00006910 vha-1 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in several processes, including lysosomal lumen acidification; ovulation; and regulation of syncytium formation by plasma membrane fusion. Located in membrane raft. Expressed in excretory cell and rectum. Human ortholog(s) of this gene implicated in thyroid gland carcinoma. Is an ortholog of human ATP6V0C (ATPase H+ transporting V0 subunit c). WB:WBGene00006911 vha-2 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in programmed cell death and proton transmembrane transport. Predicted to be located in membrane. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Expressed in excretory cell and rectum. Human ortholog(s) of this gene implicated in thyroid gland carcinoma. Is an ortholog of human ATP6V0C (ATPase H+ transporting V0 subunit c). WB:WBGene00006912 vha-3 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Expressed in excretory cell; hypodermis; and intestinal cell. Human ortholog(s) of this gene implicated in thyroid gland carcinoma. Is an ortholog of human ATP6V0C (ATPase H+ transporting V0 subunit c). WB:WBGene00006913 vha-4 Predicted to enable proton transmembrane transporter activity. Involved in embryo development. Predicted to be located in membrane. Predicted to be part of proton-transporting two-sector ATPase complex, proton-transporting domain. Expressed in excretory cell and rectum. Is an ortholog of human ATP6V0B (ATPase H+ transporting V0 subunit b). WB:WBGene00006914 vha-5 Predicted to enable ATPase binding activity. Involved in several processes, including collagen and cuticulin-based cuticle development; exosomal secretion; and multicellular organismal-level water homeostasis. Located in apical plasma membrane; cell body membrane; and cytoplasmic vesicle. Part of vacuolar proton-transporting V-type ATPase complex. Expressed in several structures, including excretory cell; hypodermis; neuronal sheath cell; pharynx; and vulva. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive cutis laxa type IIA; autosomal recessive osteopetrosis 1; and developmental and epileptic encephalopathy 104. Is an ortholog of several human genes including ATP6V0A1 (ATPase H+ transporting V0 subunit a1); ATP6V0A2 (ATPase H+ transporting V0 subunit a2); and TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3). WB:WBGene00006915 vha-6 Predicted to enable ATPase binding activity. Involved in nematode larval development. Located in apical plasma membrane. Part of vacuolar proton-transporting V-type ATPase complex. Expressed in Psub2; excretory cell; hypodermis; pharyngeal-intestinal valve; and uterus. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive cutis laxa type IIA; autosomal recessive osteopetrosis 1; and developmental and epileptic encephalopathy 104. Is an ortholog of several human genes including ATP6V0A1 (ATPase H+ transporting V0 subunit a1); ATP6V0A2 (ATPase H+ transporting V0 subunit a2); and TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3). WB:WBGene00006916 vha-7 Predicted to enable ATPase binding activity. Predicted to be involved in vacuolar acidification. Predicted to be located in plasma membrane. Predicted to be part of vacuolar proton-transporting V-type ATPase complex. Expressed in hypodermis; spermatheca; and uterus. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive cutis laxa type IIA; autosomal recessive osteopetrosis 1; and developmental and epileptic encephalopathy 104. Is an ortholog of several human genes including ATP6V0A1 (ATPase H+ transporting V0 subunit a1); ATP6V0A2 (ATPase H+ transporting V0 subunit a2); and TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3). WB:WBGene00006917 vha-8 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Located in apical plasma membrane and cytoplasm. Expressed in head; hypodermis; and intestine. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIC. Is an ortholog of human ATP6V1E2 (ATPase H+ transporting V1 subunit E2). WB:WBGene00006918 vha-9 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in lysosomal lumen acidification. Predicted to be located in membrane. Predicted to be part of proton-transporting V-type ATPase, V1 domain. Is an ortholog of human ATP6V1F (ATPase H+ transporting V1 subunit F). WB:WBGene00006919 vha-10 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in positive regulation of programmed cell death and programmed cell death. Predicted to be part of vacuolar proton-transporting V-type ATPase complex. Is an ortholog of human ATP6V1G2 (ATPase H+ transporting V1 subunit G2). WB:WBGene00006920 vha-11 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in embryo development and ovulation. Predicted to be located in cytoplasm and membrane. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Expressed in excretory cell; hypodermis; and intestinal cell. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma and stomach carcinoma. Is an ortholog of human ATP6V1C1 (ATPase H+ transporting V1 subunit C1). WB:WBGene00006921 vha-12 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in several processes, including positive regulation of apoptotic process involved in development; positive regulation of neurotransmitter secretion; and regulation of intracellular pH. Predicted to be part of proton-transporting V-type ATPase, V1 domain. Expressed in excretory pore; hypodermal cell; muscle cell; neurons; and somatic cell. Human ortholog(s) of this gene implicated in autosomal dominant congenital deafness with onychodystrophy and renal tubular acidosis. Is an ortholog of human ATP6V1B2 (ATPase H+ transporting V1 subunit B2). WB:WBGene00006922 vhl-1 Involved in response to hypoxia. Part of Cul2-RING ubiquitin ligase complex. Expressed in several structures, including ADFL and ADFR. Used to study clear cell renal cell carcinoma and von Hippel-Lindau disease. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); familial erythrocytosis 2; and von Hippel-Lindau disease. Is an ortholog of human VHL (von Hippel-Lindau tumor suppressor). WB:WBGene00006923 vhp-1 Enables JUN kinase phosphatase activity and MAP kinase tyrosine/serine/threonine phosphatase activity. Involved in several processes, including regulation of cellular response to stress; regulation of defense response to bacterium; and regulation of protein localization to nucleus. Acts upstream of with a negative effect on protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human DUSP16 (dual specificity phosphatase 16) and DUSP8 (dual specificity phosphatase 8). WB:WBGene00006924 vig-1 Predicted to enable RNA binding activity. Part of RISC complex. Expressed in neurons. Is an ortholog of human HABP4 (hyaluronan binding protein 4) and SERBP1 (SERPINE1 mRNA binding protein 1). WB:WBGene00006925 vit-1 Predicted to enable lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in extracellular region. WB:WBGene00006926 vit-2 Predicted to enable lipid transporter activity. Predicted to be involved in lipid transport. Located in cytoplasmic vesicle; vesicle lumen; and yolk granule. Expressed in embryonic cell; gonad; intestine; oocyte; and pseudocoelom. WB:WBGene00006927 vit-3 Predicted to enable lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in extracellular region. Expressed in intestine. WB:WBGene00006928 vit-4 Predicted to enable lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in extracellular region. WB:WBGene00006929 vit-5 Predicted to enable lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in extracellular region. WB:WBGene00006930 vit-6 Predicted to enable lipid transporter activity. Involved in negative regulation of protein oxidation; negative regulation of reactive oxygen species biosynthetic process; and positive regulation of cholesterol import. Predicted to be located in extracellular region. WB:WBGene00006931 vps-26 Predicted to be involved in intracellular protein transport and retrograde transport, endosome to Golgi. Located in cytosol. Is an ortholog of human VPS26B (VPS26 retromer complex component B). WB:WBGene00006932 vps-34 Enables 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including cellular component organization; determination of adult lifespan; and regulation of transport. Located in cytoplasm; nuclear outer membrane; and nucleolus. Is an ortholog of human PIK3C3 (phosphatidylinositol 3-kinase catalytic subunit type 3). WB:WBGene00006933 vps-35 Involved in positive regulation of protein localization to cell periphery; protein localization to postsynaptic membrane; and regulation of presynapse assembly. Located in cytosol; dendrite; and neuronal cell body. Expressed in several structures, including body wall musculature; ciliated neurons; coelomocyte; intestine; and pharynx. Human ortholog(s) of this gene implicated in Parkinson's disease 17. Is an ortholog of human VPS35 (VPS35 retromer complex component). WB:WBGene00006934 vps-54 Enables syntaxin binding activity. Predicted to be involved in Golgi to vacuole transport and retrograde transport, endosome to Golgi. Part of GARP complex. Expressed in body wall musculature. Is an ortholog of human VPS54 (VPS54 subunit of GARP complex). WB:WBGene00006935 vars-1 Predicted to enable valine-tRNA ligase activity. Predicted to be involved in valyl-tRNA aminoacylation. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 20. Is an ortholog of human VARS2 (valyl-tRNA synthetase 2, mitochondrial). WB:WBGene00006936 glp-4 Predicted to enable valine-tRNA ligase activity. Involved in determination of adult lifespan. Predicted to be located in cytosol. Is an ortholog of human VARS1 (valyl-tRNA synthetase 1). WB:WBGene00006937 wah-1 Enables enzyme binding activity. Involved in apoptotic DNA fragmentation and positive regulation of phosphatidylserine exposure on apoptotic cell surface. Located in cytosol; mitochondrion; and nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; X-linked recessive disease (multiple); and dilated cardiomyopathy 1H. Is an ortholog of human AIFM1 (apoptosis inducing factor mitochondria associated 1). WB:WBGene00006938 wee-1.1 Predicted to enable protein kinase activity. Predicted to be involved in meiotic cell cycle and negative regulation of G2/MI transition of meiotic cell cycle. Predicted to be located in cytoplasm and nucleus. Expressed in Ea and Ep. Is an ortholog of human PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1). WB:WBGene00006939 wee-1.2 Is affected by several genes including daf-2; eat-2; and unc-30 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; stavudine; and Psoralens based on RNA-seq studies. WB:WBGene00006940 wee-1.3 Enables cyclin-dependent protein serine/threonine kinase inhibitor activity. Involved in several processes, including negative regulation of reproductive process; nematode larval development; and sexual reproduction. Acts upstream of or within nematode male tail tip morphogenesis. Located in several cellular components, including condensed chromosome; nuclear envelope; and perinuclear endoplasmic reticulum. Expressed in several structures, including germ line; intestine; oocyte; somatic cell; and spermatheca. Is an ortholog of human PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1). WB:WBGene00006941 wnk-1 Enables molecular condensate scaffold activity. Involved in several processes, including cell volume homeostasis; cellular hyperosmotic response; and multicellular organismal-level water homeostasis. Predicted to be located in cytoplasm. Expressed in body wall musculature; excretory cell; and spermatheca. Used to study pseudohypoaldosteronism. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 2A; hypertension; and pseudohypoaldosteronism. Is an ortholog of several human genes including WNK1 (WNK lysine deficient protein kinase 1); WNK3 (WNK lysine deficient protein kinase 3); and WNK4 (WNK lysine deficient protein kinase 4). WB:WBGene00006942 wrk-1 Predicted to enable axon guidance receptor activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules and synapse organization. Predicted to be located in axon; neuronal cell body; and plasma membrane. Expressed in several structures, including SMDVL; body ganglion; head neurons; hermaphrodite distal tip cell; and interfacial epithelial cell. WB:WBGene00006943 wrm-1 Enables several functions, including nuclear receptor binding activity; protein serine/threonine kinase activator activity; and transcription coactivator activity. Contributes to protein kinase activity. Involved in several processes, including axis specification; digestive tract development; and regulation of developmental process. Located in cell cortex and nucleus. Part of serine/threonine protein kinase complex. Expressed in several structures, including E; Psub2; gonadal primordium; linker cell; and seam cell. WB:WBGene00006944 wrn-1 Enables 3'-5' DNA helicase activity. Involved in DNA metabolic process; determination of adult lifespan; and response to ionizing radiation. Located in nucleoplasm and site of double-strand break. Expressed in several structures, including AWCL; AWCR; and germ line. Used to study Werner syndrome. Human ortholog(s) of this gene implicated in several diseases, including Werner syndrome; diffuse scleroderma; and senile cataract. Is an ortholog of human WRN (WRN RecQ like helicase). WB:WBGene00006945 wars-1 Predicted to enable tryptophan-tRNA ligase activity. Predicted to be involved in tryptophanyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in distal hereditary motor neuronopathy type 9. Is an ortholog of human WARS1 (tryptophanyl-tRNA synthetase 1). WB:WBGene00006946 prx-10 Predicted to enable tryptophan-tRNA ligase activity. Predicted to be involved in mitochondrial tryptophanyl-tRNA aminoacylation. Predicted to be located in mitochondrial matrix. Used to study obesity. Is an ortholog of human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial). WB:WBGene00006947 wrt-1 Predicted to enable peptidase activity. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cell surface; extracellular space; and plasma membrane. Expressed in hyp10; hyp6; hyp7 syncytium; hyp8; and hyp9. WB:WBGene00006948 wrt-2 Expressed in hypodermal cell and hypodermis. WB:WBGene00006949 wrt-3 Predicted to be located in extracellular region. Expressed in hermaphrodite distal tip cell; hypodermis; muscle cell; and pharyngeal gland cell. WB:WBGene00006950 wrt-4 Predicted to enable peptidase activity. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cell surface; extracellular space; and plasma membrane. Expressed in hyp10; hyp6; hyp7 syncytium; hyp8; and hyp9. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; gastrointestinal system cancer (multiple); and glomerulonephritis (multiple). Is an ortholog of human SHH (sonic hedgehog signaling molecule). WB:WBGene00006951 wrt-5 Predicted to enable signaling receptor binding activity. Predicted to be involved in cell communication. Predicted to be located in extracellular region. Expressed in several structures, including excretory system; hermaphrodite gonad; pharyngeal-intestinal valve; phasmid socket cell; and rectal valve cell. WB:WBGene00006952 wrt-6 Predicted to enable peptidase activity. Predicted to be involved in cell-cell signaling; protein autoprocessing; and system development. Predicted to be located in cell surface; extracellular space; and plasma membrane. Expressed in anterior ganglion (ant); hypodermis; and neuronal sheath cell. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; gastrointestinal system cancer (multiple); and glomerulonephritis (multiple). Is an ortholog of human SHH (sonic hedgehog signaling molecule). WB:WBGene00006953 wrt-7 Predicted to be involved in protein autoprocessing. Predicted to be located in extracellular region. WB:WBGene00006954 wrt-8 Predicted to enable peptidase activity. Predicted to be involved in cell-cell signaling; protein autoprocessing; and system development. Predicted to be located in cell surface; extracellular space; and plasma membrane. Expressed in hyp10; hyp6; hyp7 syncytium; hyp8; and hyp9. WB:WBGene00006955 wrt-9 Expressed in hypodermis. WB:WBGene00006956 wrt-10 Expressed in hypodermis; interfacial epithelial cell; and intestine. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00006957 wsp-1 Enables cytoskeletal regulatory protein binding activity and small GTPase binding activity. Involved in several processes, including embryonic morphogenesis; positive regulation of egg-laying behavior; and regulation of cellular component organization. Located in cell leading edge; cortical actin cytoskeleton; and presynaptic periactive zone. Expressed in Q cell; anchor cell; apoptotic cell; epithelial cell; and hypodermis. Is an ortholog of human WASL (WASP like actin nucleation promoting factor). WB:WBGene00006958 wve-1 Predicted to enable Arp2/3 complex binding activity and protein kinase A regulatory subunit binding activity. Involved in several processes, including generation of neurons; positive regulation of clathrin-dependent endocytosis; and positive regulation of egg-laying behavior. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of SCAR complex. Expressed in Q cell and anchor cell. Is an ortholog of human WASF1 (WASP family member 1); WASF2 (WASP family member 2); and WASF3 (WASP family member 3). WB:WBGene00006959 xbp-1 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including defense response to Gram-negative bacterium; determination of adult lifespan; and endoplasmic reticulum unfolded protein response. Predicted to be located in nucleus. Expressed widely. Is an ortholog of human XBP1 (X-box binding protein 1). WB:WBGene00006960 xbx-1 Predicted to enable dynein heavy chain binding activity. Involved in intraciliary retrograde transport and non-motile cilium assembly. Located in cilium. Expressed in neurons. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Is an ortholog of human DYNC2LI1 (dynein cytoplasmic 2 light intermediate chain 1). WB:WBGene00006961 xnp-1 Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and catalytic activity, acting on a nucleic acid. Involved in several processes, including embryo development; gonad development; and vulval development. Predicted to be located in nucleus. Expressed in germ line; hermaphrodite gonad; and vulval precursor cell. Used to study intellectual disability. Human ortholog(s) of this gene implicated in several diseases, including X-linked mental retardation-hypotonic facies syndrome-1; alpha thalassemia-X-linked intellectual disability syndrome; and lung carcinoma (multiple). Is an ortholog of human ATRX (ATRX chromatin remodeler). WB:WBGene00006962 xol-1 Involved in dosage compensation by hypoactivation of X chromosome; intergenic mRNA trans splicing; and male sex determination. Predicted to be located in nucleus. WB:WBGene00006963 xpa-1 Predicted to enable damaged DNA binding activity. Involved in several processes, including DNA repair; determination of adult lifespan; and response to UV-C. Located in nucleus. Human ortholog(s) of this gene implicated in xeroderma pigmentosum group A. Is an ortholog of human XPA (XPA, DNA damage recognition and repair factor). WB:WBGene00006964 xrn-2 Enables 5'-3' RNA exonuclease activity. Involved in several processes, including miRNA catabolic process; negative regulation of miRNA-mediated gene silencing; and regulation of vulval development. Located in nucleus. Expressed in M5 neuron; PVT; intestine; and pharyngeal epithelial cell. Human ortholog(s) of this gene implicated in adenoid cystic carcinoma; leiomyosarcoma; and lung cancer. Is an ortholog of human XRN2 (5'-3' exoribonuclease 2). WB:WBGene00006965 xtr-1 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in germ-line sex determination. Predicted to be located in plasma membrane. WB:WBGene00006966 xtr-2 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in germ-line sex determination. Predicted to be located in plasma membrane. WB:WBGene00006967 yrn-1 Part of ribonucleoprotein complex. WB:WBGene00006968 yars-2 Predicted to enable tyrosine-tRNA ligase activity. Predicted to be involved in tRNA aminoacylation. Predicted to be located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in myopathy, lactic acidosis, and sideroblastic anemia 2. Is an ortholog of human YARS2 (tyrosyl-tRNA synthetase 2). WB:WBGene00006970 zag-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; neuron differentiation; and regulation of cell differentiation. Located in nucleus. Expressed in body wall musculature; enteric muscle; neurons; pharynx; and somatic nervous system. Human ortholog(s) of this gene implicated in Hirschsprung's disease; Mowat-Wilson syndrome; and corneal dystrophy (multiple). Is an ortholog of human ZEB1 (zinc finger E-box binding homeobox 1) and ZEB2 (zinc finger E-box binding homeobox 2). WB:WBGene00006971 zak-1 Enables MAP kinase kinase kinase activity. Involved in stress-activated MAPK cascade. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in centronuclear myopathy 6 with fiber-type disproportion. Is an ortholog of human MAP3K20 (mitogen-activated protein kinase kinase kinase 20). WB:WBGene00006972 zen-2 No description available WB:WBGene00006973 zen-3 No description available WB:WBGene00006974 zen-4 Enables several functions, including identical protein binding activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Involved in several processes, including nuclear division; pronuclear migration; and regulation of actomyosin contractile ring contraction. Located in cleavage furrow; microtubule cytoskeleton; and midbody. Part of centralspindlin complex. Expressed in germ cell and gonad. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia type III. Is an ortholog of human KIF23 (kinesin family member 23). WB:WBGene00006975 zfp-1 Enables chromatin binding activity and methylated histone binding activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in condensed chromosome and nucleus. Expressed in several structures, including germ line; intestine; oocyte; pharynx; and seam cell. Human ortholog(s) of this gene implicated in acute monocytic leukemia and acute myeloid leukemia. Is an ortholog of human MLLT10 (MLLT10 histone lysine methyltransferase DOT1L cofactor) and MLLT6 (MLLT6, PHD finger containing). WB:WBGene00006976 zhp-3 Predicted to enable SUMO transferase activity. Involved in embryo development; meiotic chromosome segregation; and synaptonemal complex disassembly. Located in synaptonemal complex. Is an ortholog of human RNF212B (ring finger protein 212B). WB:WBGene00006977 zif-1 Involved in embryo development and ubiquitin-dependent protein catabolic process. WB:WBGene00006978 zig-1 Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in axon and plasma membrane. Expressed in ASEL; ASER; PVT; body wall musculature; and neurons. WB:WBGene00006979 zig-2 Predicted to be involved in axon guidance and cell adhesion. Predicted to be located in extracellular region and plasma membrane. Expressed in ASIL; ASIR; PVT; and head neurons. WB:WBGene00006980 zig-3 Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in axon and plasma membrane. Expressed in ASI; body wall musculature; nerve ring neurons; and vulva. WB:WBGene00006981 zig-4 Involved in neuron development. Predicted to be located in extracellular region and plasma membrane. Expressed in neurons and pharynx. WB:WBGene00006982 zig-5 Involved in pattern specification process. Predicted to be located in membrane. Expressed in ganglia. WB:WBGene00006983 zig-6 Involved in homeostatic process. Predicted to be located in neuron projection membrane. Expressed in body wall musculature; enteric muscle; head neurons; and vulval muscle. WB:WBGene00006984 zig-7 Predicted to be located in extracellular region. Expressed in body wall musculature. WB:WBGene00006985 zig-8 Predicted to be involved in synapse organization. Predicted to be located in neuron projection membrane. Expressed in PVT; head; and pharyngeal muscle cell. WB:WBGene00006986 zip-1 Predicted to enable DNA binding activity. WB:WBGene00006987 zmp-1 Enables metallopeptidase activity. Involved in basement membrane disassembly. Located in cell surface. Expressed in several structures, including P6.paal; P6.paar; P6.papl; gonad; and vulval cell. Human ortholog(s) of this gene implicated in prostate cancer and transitional cell carcinoma. Is an ortholog of human MMP15 (matrix metallopeptidase 15) and MMP24 (matrix metallopeptidase 24). WB:WBGene00006988 zyg-1 Enables identical protein binding activity and protein serine/threonine kinase activity. Involved in several processes, including non-membrane-bounded organelle assembly; regulation of cell cycle; and regulation of protein localization. Located in centriole and centrosome. WB:WBGene00006990 zyg-3 No description available WB:WBGene00006991 zyg-5 No description available WB:WBGene00006992 zyg-7 No description available WB:WBGene00006993 zyg-8 Enables microtubule binding activity. Involved in establishment of mitotic spindle localization; negative regulation of microtubule depolymerization; and response to temperature stimulus. Located in cytoplasm and microtubule cytoskeleton. Expressed in several structures, including amphid neurons; germ line; motor neurons; touch receptor neurons; and ventral nerve cord. Used to study dyslexia. Is an ortholog of human DCLK1 (doublecortin like kinase 1) and DCLK2 (doublecortin like kinase 2). WB:WBGene00006994 zyg-9 Predicted to enable microtubule binding activity and microtubule plus end polymerase. Involved in embryo development; meiotic spindle organization; and spindle elongation. Located in cytoplasm; kinetochore; and microtubule cytoskeleton. Is an ortholog of human CKAP5 (cytoskeleton associated protein 5). WB:WBGene00006995 zyg-10 No description available WB:WBGene00006996 zyg-11 Enables cyclin binding activity. Involved in several processes, including anaphase-promoting complex-dependent catabolic process; positive regulation of metaphase/anaphase transition of meiotic cell cycle; and sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation. Part of Cul2-RING ubiquitin ligase complex. Is an ortholog of human ZYG11B (zyg-11 family member B, cell cycle regulator). WB:WBGene00006997 zyg-12 Enables dynein light intermediate chain binding activity and protein self-association. Involved in several processes, including centrosome localization; chromosome segregation; and pronuclear migration. Located in centrosome and nuclear envelope. Expressed in gonad and oocyte. Used to study Emery-Dreifuss muscular dystrophy. Is an ortholog of human HOOK1 (hook microtubule tethering protein 1) and HOOK2 (hook microtubule tethering protein 2). WB:WBGene00006998 zyg-13 No description available WB:WBGene00006999 zyx-1 Enables DEAD/H-box RNA helicase binding activity. Involved in maintenance of synapse structure. Acts upstream of or within with a positive effect on smooth muscle contraction. Located in M band; nucleus; and striated muscle dense body. Expressed in muscle cell and neurons. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Is an ortholog of human LPP (LIM domain containing preferred translocation partner in lipoma) and TRIP6 (thyroid hormone receptor interactor 6). WB:WBGene00007000 tufm-1 Predicted to enable translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 4. Is an ortholog of human TUFM (Tu translation elongation factor, mitochondrial). WB:WBGene00007001 tufm-2 Predicted to enable translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Predicted to be located in mitochondrion. WB:WBGene00007002 pre-1 Acts upstream of or within determination of adult lifespan; multicellular organism reproduction; and multicellular organismal response to stress. WB:WBGene00007003 pre-7 Acts upstream of or within determination of adult lifespan; multicellular organism reproduction; and multicellular organismal response to stress. WB:WBGene00007004 pre-33 Acts upstream of or within determination of adult lifespan; multicellular organism reproduction; and multicellular organismal response to stress. WB:WBGene00007005 ssc-3 No description available WB:WBGene00007006 npr-3 Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to be located in membrane. Expressed in ventral cord neurons. Human ortholog(s) of this gene implicated in hypertension. Is an ortholog of human PRLHR (prolactin releasing hormone receptor). WB:WBGene00007007 mak-2 Enables mitogen-activated protein kinase binding activity. Involved in several processes, including behavioral response to nicotine; positive regulation of 3'-UTR-mediated mRNA stabilization; and regulation of axon extension. Located in cytoplasm; nucleus; and synapse. Expressed in body wall musculature; intestine; and pharynx. Human ortholog(s) of this gene implicated in patterned macular dystrophy 3. Is an ortholog of human MAPKAPK2 (MAPK activated protein kinase 2) and MAPKAPK3 (MAPK activated protein kinase 3). WB:WBGene00007008 rfp-1 Enables ubiquitin conjugating enzyme binding activity. Involved in glycolipid metabolic process. Located in nucleus. Expressed in germ line; intestinal cell; nerve ring; oocyte; and pharynx. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human RNF20 (ring finger protein 20) and RNF40 (ring finger protein 40). WB:WBGene00007009 wwp-1 Enables ubiquitin conjugating enzyme activity. Involved in defense response to bacterium; protein ubiquitination; and regulation of protein catabolic process. Acts upstream of or within determination of adult lifespan. Located in cytoplasm. Expressed in GABAergic neurons; cholinergic neurons; coelomocyte; somatic neurons; and vulval muscle. Is an ortholog of human WWP1 (WW domain containing E3 ubiquitin protein ligase 1) and WWP2 (WW domain containing E3 ubiquitin protein ligase 2). WB:WBGene00007010 alx-1 Enables Notch binding activity. Involved in cellular localization; endosome organization; and regulation of protein catabolic process. Located in basolateral plasma membrane; multivesicular body; and recycling endosome. Expressed in several structures, including vulva. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Is an ortholog of human PDCD6IP (programmed cell death 6 interacting protein). WB:WBGene00007011 mdt-1.2 Predicted to be located in nucleus. WB:WBGene00007012 mdt-4 Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex. Human ortholog(s) of this gene implicated in cervical cancer. Is an ortholog of human MED4 (mediator complex subunit 4). WB:WBGene00007013 mdt-8 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is an ortholog of human MED8 (mediator complex subunit 8). WB:WBGene00007014 mdt-10 Predicted to enable transcription coregulator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Is an ortholog of human MED10 (mediator complex subunit 10). WB:WBGene00007015 mdt-11 Predicted to enable transcription coregulator activity. Predicted to be involved in DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Is an ortholog of human MED11 (mediator complex subunit 11). WB:WBGene00007016 mdt-15 Enables nuclear receptor binding activity and transcription coactivator activity. Involved in several processes, including determination of adult lifespan; nematode larval development; and sequestering of triglyceride. Predicted to be located in nucleus. Predicted to be part of mediator complex. Expressed in head. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human MED15 (mediator complex subunit 15). WB:WBGene00007017 mdt-17 Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Human ortholog(s) of this gene implicated in infantile cerebral and cerebellar atrophy with postnatal progressive microcephaly. Is an ortholog of human MED17 (mediator complex subunit 17). WB:WBGene00007018 mdt-18 Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II and termination of RNA polymerase II transcription. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is an ortholog of human MED18 (mediator complex subunit 18). WB:WBGene00007019 mdt-19 Predicted to enable transcription coregulator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Is an ortholog of human MED19 (mediator complex subunit 19). WB:WBGene00007020 mdt-20 Predicted to enable transcription coactivator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus and protein-containing complex. Predicted to be part of mediator complex. Is an ortholog of human MED20 (mediator complex subunit 20). WB:WBGene00007021 immp-1 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Predicted to be located in membrane. Predicted to be part of mitochondrial inner membrane peptidase complex. Is an ortholog of human IMMP1L (inner mitochondrial membrane peptidase subunit 1). WB:WBGene00007022 mdt-22 Predicted to enable transcription coregulator activity. Predicted to be involved in DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Is an ortholog of human MED22 (mediator complex subunit 22). WB:WBGene00007023 mdt-27 Predicted to be located in nucleus. Predicted to be part of mediator complex. WB:WBGene00007024 plin-1 Involved in embryo development. Predicted to be located in lipid droplet. Expressed in germ line; hypodermal cell; and intestinal cell. WB:WBGene00007025 mdt-29 Involved in lateral inhibition; positive regulation of Notch signaling pathway; and regulation of cell fate specification. Predicted to be located in nucleus. Predicted to be part of mediator complex. Expressed in body wall musculature. WB:WBGene00007026 mdt-31 Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is an ortholog of human MED31 (mediator complex subunit 31). WB:WBGene00007027 ssl-1 Predicted to enable ATP hydrolysis activity and histone binding activity. Involved in negative regulation of cell fate specification. Predicted to be located in nucleus. Predicted to be part of Swr1 complex. Human ortholog(s) of this gene implicated in Floating-Harbor syndrome. Is an ortholog of human SRCAP (Snf2 related CREBBP activator protein). WB:WBGene00007028 trr-1 Involved in negative regulation of vulval development; positive regulation of growth rate; and reproduction. Located in condensed chromosome and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and germ line. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 75. Is an ortholog of human TRRAP (transformation/transcription domain associated protein). WB:WBGene00007029 mys-1 Predicted to enable histone H4K16 acetyltransferase activity and transcription coregulator activity. Involved in several processes, including negative regulation of DNA-templated transcription; negative regulation of cell fate specification; and protein localization to chromatin. Predicted to be located in nucleus. Predicted to be part of MSL complex. Used to study obesity. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human KAT5 (lysine acetyltransferase 5). WB:WBGene00007030 epc-1 Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Piccolo NuA4 histone acetyltransferase complex. Expressed in tail. Is an ortholog of human EPC1 (enhancer of polycomb homolog 1). WB:WBGene00007031 erf-1 Acts upstream of or within nematode male tail tip morphogenesis. WB:WBGene00007032 erf-2 Acts upstream of or within nematode male tail tip morphogenesis. WB:WBGene00007033 erf-3 No description available WB:WBGene00007034 erf-4 No description available WB:WBGene00007035 erf-5 No description available WB:WBGene00007036 sod-5 Predicted to enable copper ion binding activity and superoxide dismutase activity. Predicted to be involved in removal of superoxide radicals. Expressed in amphid neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); eye disease (multiple); and glucose metabolism disease (multiple). Is an ortholog of human SOD1 (superoxide dismutase 1). WB:WBGene00007038 gon-16 No description available WB:WBGene00007039 gon-15 No description available WB:WBGene00007041 tag-180 Predicted to enable voltage-gated calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated calcium channel complex. Expressed in head neurons; intestine; and tail neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 110. Is an ortholog of human CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1) and CACNA2D2 (calcium voltage-gated channel auxiliary subunit alpha2delta 2). WB:WBGene00007042 pbrm-1 Predicted to enable chromatin binding activity. Involved in gonad development. Predicted to be located in nucleus. Predicted to be part of RSC-type complex and SWI/SNF complex. Expressed in head; somatic cell; tail; and tail precursor cell. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Crohn's disease; carcinoma (multiple); and colorectal cancer. Is an ortholog of human PBRM1 (polybromo 1). WB:WBGene00007043 algn-10 Predicted to enable dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in long QT syndrome 2. Is an ortholog of human ALG10 (ALG10 alpha-1,2-glucosyltransferase) and ALG10B (ALG10 alpha-1,2-glucosyltransferase B). WB:WBGene00007044 cpna-5 Predicted to enable calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion. Predicted to be located in plasma membrane. Expressed in neurons. WB:WBGene00007045 pgap-2 Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 3. Is an ortholog of human PGAP2 (post-GPI attachment to proteins 2). WB:WBGene00007047 wts-1 Enables protein kinase activity and transcription coactivator binding activity. Involved in several processes, including apical protein localization; determination of adult lifespan; and digestive tract development. Located in apical plasma membrane and cytoplasm. Expressed in several structures, including excretory canal; hypodermis; intestine; spermatheca; and vulva. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human LATS1 (large tumor suppressor kinase 1). WB:WBGene00007048 nfx-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human NFX1 (nuclear transcription factor, X-box binding 1). WB:WBGene00007049 tag-191 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00007050 utp-20 Predicted to be located in nucleolus. Predicted to be part of 90S preribosome and small-subunit processome. Is an ortholog of human UTP20 (UTP20 small subunit processome component). WB:WBGene00007053 chd-7 Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and chromatin binding activity. Predicted to be involved in chromatin remodeling and regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of chromatin. Used to study CHARGE syndrome. Human ortholog(s) of this gene implicated in CHARGE syndrome and hypogonadotropic hypogonadism 5 with or without anosmia. Is an ortholog of human CHD6 (chromodomain helicase DNA binding protein 6). WB:WBGene00007054 scpl-1 Enables several functions, including LIM domain binding activity; kinase binding activity; and protein-macromolecule adaptor activity. Involved in dephosphorylation and regulation of egg-laying behavior. Located in I band and M band. Expressed in body wall musculature; pharyngeal muscle cell; and vulval muscle. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human CTDSP1 (CTD small phosphatase 1) and CTDSPL (CTD small phosphatase like). WB:WBGene00007055 tag-196 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Expressed in intestine and tail. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 13. Is an ortholog of human CTSF (cathepsin F). WB:WBGene00007056 crn-7 Enables deoxyribonuclease II activity. Involved in apoptotic DNA fragmentation. Acts upstream of or within with a positive effect on negative regulation of antimicrobial peptide production. Expressed in body wall musculature and head muscle. Is an ortholog of human DNASE2 (deoxyribonuclease 2, lysosomal). WB:WBGene00007057 ant-1.2 Predicted to enable ATP:ADP antiporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Located in mitochondrion. Expressed in body wall musculature; head neurons; intestine; pharynx; and seam cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6). WB:WBGene00007058 dmd-6 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to be located in nucleus. Expressed in several structures, including neurons; pharynx; rectum; tail; and vulva. WB:WBGene00007059 vps-52 Enables small GTPase binding activity and syntaxin binding activity. Involved in negative regulation of dense core granule transport; positive regulation of dense core granule transport; and positive regulation of locomotion involved in locomotory behavior. Located in Golgi cisterna; perikaryon; and perinuclear region of cytoplasm. Part of GARP complex. Expressed in distal tip cell; neurons; somatic cell; and somatic gonad. Is an ortholog of human VPS52 (VPS52 subunit of GARP complex). WB:WBGene00007060 wht-6 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including gout; hematologic cancer (multiple); and toxic encephalopathy. Is an ortholog of human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)). WB:WBGene00007062 ebp-3 Predicted to enable microtubule plus-end binding activity. Predicted to be involved in protein localization to microtubule; regulation of microtubule polymerization or depolymerization; and spindle assembly. Predicted to be located in microtubule cytoskeleton. Human ortholog(s) of this gene implicated in congenital symmetric circumferential skin creases 2. Is an ortholog of human MAPRE1 (microtubule associated protein RP/EB family member 1); MAPRE2 (microtubule associated protein RP/EB family member 2); and MAPRE3 (microtubule associated protein RP/EB family member 3). WB:WBGene00007063 2L52.1 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalppappa; ABarappppa; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by five chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00007064 rga-9 Predicted to enable GTPase activator activity. Predicted to be involved in signal transduction. WB:WBGene00007065 pot-3 Predicted to enable single-stranded telomeric DNA binding activity. Predicted to be located in chromosome, telomeric region and nucleus. WB:WBGene00007066 3R5.2 Is affected by several genes including daf-16; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00007067 rabr-2 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in vesicle-mediated transport. WB:WBGene00007068 cTel55X.1 Predicted to be located in endomembrane system. WB:WBGene00007070 ugt-49 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00007071 AC3.5 Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be located in cytoplasm. WB:WBGene00007072 ugt-1 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00007073 ugt-2 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1); UGT3A2 (UDP glycosyltransferase family 3 member A2); and UGT8 (UDP glycosyltransferase 8). WB:WBGene00007074 AC8.2 Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride and Diazinon based on microarray studies. WB:WBGene00007075 AC8.3 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00007076 AC8.4 Enriched in head mesodermal cell and intestine based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including metformin; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007077 AC8.5 Is affected by several genes including daf-16; dpy-21; and cyc-1 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Atrazine; and cadmium based on RNA-seq and microarray studies. WB:WBGene00007078 AC8.6 Is affected by several genes including daf-16; let-60; and sir-2.1 based on microarray and RNA-seq studies. WB:WBGene00007079 AC8.7 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00007080 sfxn-1.1 Predicted to enable serine transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human SFXN1 (sideroflexin 1) and SFXN3 (sideroflexin 3). WB:WBGene00007081 AH6.3 Predicted to be located in membrane. WB:WBGene00007082 acs-10 Predicted to enable CoA-ligase activity. WB:WBGene00007083 AH10.2 Predicted to be located in membrane. WB:WBGene00007085 AH10.4 Enriched in head mesodermal cell; neurons; and pharynx based on RNA-seq studies. Is affected by several genes including daf-12; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; Oligosaccharides; and fluoranthene based on RNA-seq and microarray studies. WB:WBGene00007087 B0001.2 Enriched in several structures, including body wall muscle cell; germ line; germline precursor cell; gonadal sheath cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on proteomic; microarray; and RNA-seq studies. Is affected by thirteen chemicals including manganese chloride; D-glucose; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF272) and Protein of unknown function DUF272. WB:WBGene00007088 B0001.3 Enriched in body wall muscle cell; germ line; sensory neurons; and somatic gonad precursor based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and fbf-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including D-glucose; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00007089 B0001.4 Predicted to enable ATP binding activity; cytidine kinase activity; and uridine kinase activity. Predicted to be involved in phosphorylation and pyrimidine ribonucleotide biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human UCK1 (uridine-cytidine kinase 1). WB:WBGene00007090 B0001.5 Enriched in several structures, including ABplaapaap; ABpraapaap; germ line; germline precursor cell; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and lin-35 based on microarray and RNA-seq studies. Is affected by eleven chemicals including D-glucose; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007091 eri-12 Located in cytoplasm. WB:WBGene00007092 B0001.7 Enriched in RIBL; RIBR; germ line; germline precursor cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; gld-1; and elt-2 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including manganese chloride; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00007093 B0001.8 Enriched in RIB; germ line; germline precursor cell; intestine; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-10; eat-2; and pmk-1 based on microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00007094 B0019.2 Enriched in ABplapapppp; ABprapapppp; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by nine chemicals including D-glucose; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545); Homeobox-like domain superfamily; SPK domain; and Phosphorylation site. WB:WBGene00007096 B0024.3 Predicted to be located in membrane. WB:WBGene00007097 B0024.4 Involved in defense response to Gram-negative bacterium. Located in membrane raft. WB:WBGene00007099 trx-2 Predicted to enable protein-disulfide reductase activity. Predicted to be involved in cell redox homeostasis. Located in mitochondrion. Expressed in AIY; ASEL; body wall musculature; and vulval muscle. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 29. Is an ortholog of human TXN2 (thioredoxin 2). WB:WBGene00007100 asps-1 Predicted to be involved in glucose homeostasis and intracellular protein transport. Predicted to be located in cytoplasm; nucleus; and vesicle membrane. Expressed in head; hypodermis; intestine; pharynx; and tail. Human ortholog(s) of this gene implicated in alveolar soft part sarcoma. Is an ortholog of human ASPSCR1 (ASPSCR1 tether for SLC2A4, UBX domain containing). WB:WBGene00007101 B0024.11 Predicted to enable pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in intellectual developmental disorder with abnormal behavior, microcephaly, and short stature. Is an ortholog of human PUS7 (pseudouridine synthase 7). WB:WBGene00007102 B0024.13 Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in dolichol biosynthetic process; dolichol-linked oligosaccharide biosynthetic process; and polyprenol catabolic process. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Kahrizi syndrome and congenital disorder of glycosylation Iq. Is an ortholog of human SRD5A3 (steroid 5 alpha-reductase 3). WB:WBGene00007103 crm-1 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in plasma membrane. Expressed in PVR; cholinergic neurons; and intestine. Is an ortholog of human CRIM1 (cysteine rich transmembrane BMP regulator 1). WB:WBGene00007104 B0024.15 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human B3GALT5 (beta-1,3-galactosyltransferase 5). WB:WBGene00007105 znf-207 Predicted to enable metal ion binding activity. Predicted to be located in nucleus. Expressed in muscle cell; nerve ring; nervous system; tail; and ventral nerve cord. Is an ortholog of human ZNF207 (zinc finger protein 207). WB:WBGene00007106 B0035.3 Predicted to enable ADP-ribosylglutamate hydrolase activity. Predicted to be involved in DNA damage response and purine nucleoside metabolic process. Predicted to be located in nucleoplasm. Is an ortholog of human MACROD2 (mono-ADP ribosylhydrolase 2). WB:WBGene00007107 pfd-4 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of prefoldin complex. Is an ortholog of human PFDN4 (prefoldin subunit 4). WB:WBGene00007108 gspd-1 Predicted to enable glucose-6-phosphate dehydrogenase activity. Predicted to be involved in glucose metabolic process and pentose-phosphate shunt, oxidative branch. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; diabetes mellitus (multiple); and favism. Is an ortholog of human G6PD (glucose-6-phosphate dehydrogenase). WB:WBGene00007109 edg-1 Enriched in germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including manganese chloride; bisphenol S; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00007110 leo-1 Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity. Predicted to be involved in positive regulation of transcription elongation by RNA polymerase II. Located in nucleus. Is an ortholog of human LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component). WB:WBGene00007111 sart-3 Enables U4 snRNA binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleoplasm. Is an ortholog of human SART3 (spliceosome associated factor 3, U4/U6 recycling protein). WB:WBGene00007112 B0035.13 Predicted to be involved in lipid metabolic process. WB:WBGene00007113 B0035.15 Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 15. Is an ortholog of human NDUFAF4 (NADH:ubiquinone oxidoreductase complex assembly factor 4). WB:WBGene00007114 mttu-1 Predicted to enable ATP binding activity; tRNA binding activity; and tRNA-5-taurinomethyluridine 2-sulfurtransferase. Predicted to be involved in tRNA wobble position uridine thiolation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in aminoglycoside-induced deafness; infantile liver failure syndrome; and transient infantile liver failure. Is an ortholog of human TRMU (tRNA mitochondrial 2-thiouridylase). WB:WBGene00007115 B0198.2 Predicted to be located in membrane. WB:WBGene00007116 B0198.3 Predicted to enable protein kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. WB:WBGene00007117 spe-42 Involved in single fertilization. Predicted to be located in membrane. Expressed in sperm. Is an ortholog of human DCST2 (DC-STAMP domain containing 2). WB:WBGene00007118 npp-22 Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in nuclear pore organization. Part of nuclear pore. Is an ortholog of human NDC1 (NDC1 transmembrane nucleoporin). WB:WBGene00007119 calf-1 Involved in determination of left/right asymmetry in nervous system; positive regulation of locomotion; and protein localization. Located in endoplasmic reticulum membrane. Expressed in AWCL and AWCR. WB:WBGene00007120 B0250.3 Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and unc-30 based on RNA-seq studies. WB:WBGene00007121 B0250.4 Enriched in body wall musculature; neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including sek-1; pgl-1; and isp-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including 1-methylnicotinamide; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00007122 B0250.5 Predicted to enable 3-hydroxyisobutyrate dehydrogenase activity. Predicted to be involved in valine catabolic process. Predicted to be located in mitochondrion. Is an ortholog of human HIBADH (3-hydroxyisobutyrate dehydrogenase). WB:WBGene00007123 srbc-79 Predicted to be located in membrane. WB:WBGene00007124 B0250.7 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by six chemicals including bisphenol A; bisphenol S; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007125 B0250.8 Enriched in AFD; ASER; PLM; germline precursor cell; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including clk-1; csr-1; and daf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Atrazine; and fluoranthene based on RNA-seq and microarray studies. WB:WBGene00007126 dhcr-7 Predicted to enable 7-dehydrocholesterol reductase activity and sterol delta7 reductase activity. Predicted to be involved in brassinosteroid biosynthetic process and cholesterol biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Greenberg dysplasia; Pelger-Huet anomaly; and Smith-Lemli-Opitz syndrome. Is an ortholog of human DHCR7 (7-dehydrocholesterol reductase). WB:WBGene00007127 srbc-78 Predicted to be located in membrane. WB:WBGene00007128 memb-1 Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in vesicle fusion. Predicted to be located in endomembrane system. Predicted to be part of SNARE complex. Expressed widely. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 6. Is an ortholog of human GOSR2 (golgi SNAP receptor complex member 2). WB:WBGene00007129 B0272.3 Predicted to enable 3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Expressed widely. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 4. Is an ortholog of human HADH (hydroxyacyl-CoA dehydrogenase). WB:WBGene00007130 B0272.4 Predicted to enable isomerase activity. Predicted to be located in peroxisome. Expressed widely. Is an ortholog of several human genes including CDY1 (chromodomain Y-linked 1); CDY2A (chromodomain Y-linked 2A); and CDYL (chromodomain Y like). WB:WBGene00007131 pals-26 Enriched in several structures, including Z1.p; dopaminergic neurons; excretory cell; head mesodermal cell; and male distal tip cell based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007132 pals-27 Enriched in several structures, including ABplapaaap; excretory cell; head mesodermal cell; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007133 B0284.3 Predicted to enable nucleic acid binding activity. WB:WBGene00007134 pals-28 Enriched in cephalic sheath cell and dopaminergic neurons based on tiling array studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; nanoparticle; and metformin based on microarray and RNA-seq studies. WB:WBGene00007135 cdk-12 Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in nematode larval development. Part of euchromatin. Expressed in several structures, including germ line and head. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; carcinoma (multiple); and congenital heart defects, dysmorphic facial features, and intellectual developmental disorder. Is an ortholog of human CDK13 (cyclin dependent kinase 13). WB:WBGene00007136 B0285.3 Expressed in head. WB:WBGene00007137 lcmt-1 Predicted to enable protein C-terminal leucine carboxyl O-methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in cytosol. Is an ortholog of human LCMT1 (leucine carboxyl methyltransferase 1). WB:WBGene00007138 B0285.6 Predicted to enable citrate transmembrane transporter activity and succinate transmembrane transporter activity. Predicted to be involved in citrate transport. Predicted to be located in membrane. Expressed in excretory cell. Is an ortholog of human SLC13A2 (solute carrier family 13 member 2). WB:WBGene00007139 mnp-1 Predicted to be located in cytoplasm. Expressed in Z1; Z4; body wall musculature; neuroblasts; and neurons. WB:WBGene00007140 cyp-29A4 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Is an ortholog of human CYP4V2 (cytochrome P450 family 4 subfamily V member 2). WB:WBGene00007141 pitr-4 Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Is an ortholog of human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2). WB:WBGene00007142 ttr-18 Predicted to be located in cell surface and extracellular region. WB:WBGene00007143 hacl-1 Predicted to enable thiamine pyrophosphate binding activity. Predicted to be involved in fatty acid alpha-oxidation. Predicted to be located in peroxisome. Is an ortholog of human HACL1 (2-hydroxyacyl-CoA lyase 1). WB:WBGene00007144 B0334.4 Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to be located in mitochondrial intermembrane space. Expressed in tail. Is an ortholog of human PRELID1 (PRELI domain containing 1). WB:WBGene00007145 B0334.5 Predicted to be involved in biosynthetic process. Human ortholog(s) of this gene implicated in Fanconi renotubular syndrome 5 and nuclear type mitochondrial complex I deficiency 17. Is an ortholog of human NDUFAF6 (NADH:ubiquinone oxidoreductase complex assembly factor 6). WB:WBGene00007146 npr-41 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of human GPR142 (G protein-coupled receptor 142). WB:WBGene00007147 B0334.9 Is affected by several genes including pgl-1; glh-1; and sma-4 based on RNA-seq and microarray studies. Is affected by five chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00007148 B0334.10 Enriched in germ line; neurons; and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; Doxycycline; and Chlorpyrifos based on microarray and RNA-seq studies. WB:WBGene00007149 B0334.13 Enriched in AFD; ASER; hypodermis; and seam cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; rotenone; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007150 acly-2 Predicted to enable ATP citrate synthase activity. Predicted to be involved in acetyl-CoA biosynthetic process and fatty acid biosynthetic process. Predicted to be located in cytosol. Is an ortholog of human ACLY (ATP citrate lyase). WB:WBGene00007151 B0365.2 Is affected by several genes including sir-2.1; smg-2; and adr-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube and fluoranthene based on RNA-seq and microarray studies. WB:WBGene00007152 clec-225 Enriched in AFD; MC neuron; hypodermis; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and elt-2 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; methylmercury hydroxide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00007153 clec-41 Involved in positive regulation of chemotaxis. WB:WBGene00007154 dhc-3 Predicted to enable minus-end-directed microtubule motor activity. Predicted to be involved in cilium movement involved in cell motility. Predicted to be located in 9+2 motile cilium. Predicted to be part of dynein complex. Expressed in HSN; lumbar right ganglion neurons; and outer labial neurons. WB:WBGene00007155 B0379.1 Enriched in several structures, including body wall musculature; enteric muscle; germ line; head mesodermal cell; and mechanosensory neurons based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including rotenone; D-glucose; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007156 B0379.2 Predicted to be located in membrane. WB:WBGene00007158 B0379.6 Is affected by several genes including daf-16; hpl-2; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00007159 B0379.7 Enriched in arcade cell; germ line; muscle cell; pharyngeal-intestinal valve cell; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; dpy-10; and pie-1 based on proteomic; microarray; and RNA-seq studies. Is affected by twenty-four chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00007160 B0391.1 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00007161 B0391.3 Is affected by several genes including daf-2; csr-1; and drh-3 based on RNA-seq and microarray studies. WB:WBGene00007162 fbxa-153 Enriched in several structures, including ABalaaaarl; ABalaaaarr; germ line; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00007163 fbxa-154 Enriched in several structures, including ABalppppaa; ABplpppaaa; AIZ; I5 neuron; and distal tip cell based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including eat-2; tph-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00007164 fbxa-139 Enriched in germ line and tail precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and daf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00007165 B0391.10 Enriched in several structures, including AVA; body wall muscle cell; germ line; germline precursor cell; and head mesodermal cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00007166 fbxa-152 Enriched in head mesodermal cell; neurons; retrovesicular ganglion; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; Sodium Chloride; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box A protein FB224; HTH domain in Mos1 transposase; and F-box domain. WB:WBGene00007167 rbg-3 Enables GTPase activator activity. Located in cytoplasm. Expressed in amphid neurons and phasmid neurons. Used to study obesity. Is an ortholog of human TBC1D5 (TBC1 domain family member 5). WB:WBGene00007168 B0393.3 Enriched in several structures, including GLR; ciliated neurons; germ line; male distal tip cell; and pharyngeal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eleven chemicals including manganese chloride; Zidovudine; and allantoin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Leucine Rich repeat; Leucine-rich repeat domain superfamily; and Leucine-rich repeat. Is an ortholog of human FBXL13 (F-box and leucine rich repeat protein 13). WB:WBGene00007169 B0393.4 Predicted to be involved in regulation of miRNA-mediated gene silencing and regulatory ncRNA-mediated gene silencing. WB:WBGene00007170 B0393.5 Predicted to enable calcium ion binding activity. Predicted to be an extracellular matrix structural constituent. Predicted to be involved in cell-matrix adhesion. Predicted to be located in collagen-containing extracellular matrix and membrane. WB:WBGene00007171 gex-5 Predicted to enable metal ion binding activity. WB:WBGene00007172 B0393.7 Predicted to be located in plasma membrane. WB:WBGene00007173 B0393.8 Predicted to be located in membrane. WB:WBGene00007174 mboa-1 Predicted to enable O-acyltransferase activity. Predicted to be involved in cholesterol metabolic process. Predicted to be located in endoplasmic reticulum membrane. Expressed in head and tail. Human ortholog(s) of this gene implicated in Chagas disease; coronary artery disease; and hepatocellular carcinoma. Is an ortholog of human SOAT2 (sterol O-acyltransferase 2). WB:WBGene00007175 B0395.3 Predicted to enable carnitine O-acetyltransferase activity. Predicted to be involved in carnitine metabolic process, CoA-linked. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation. Is an ortholog of human CRAT (carnitine O-acetyltransferase). WB:WBGene00007176 kcnl-1 Predicted to enable calmodulin binding activity and small conductance calcium-activated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in neuron projection; neuronal cell body; and plasma membrane. Expressed in egg-laying apparatus; enteric muscle; and neurons. Is an ortholog of human KCNN1 (potassium calcium-activated channel subfamily N member 1). WB:WBGene00007177 oac-1 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00007178 B0457.2 Enriched in hypodermis; intestine; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007179 B0457.4 Enriched in AFD; germ line; somatic gonad precursor; touch receptor neurons; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Rifampin; allantoin; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00007180 B0457.6 Enriched in several structures, including excretory cell; germline precursor cell; intestine; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by seventeen chemicals including rotenone; bisphenol A; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007181 B0462.1 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Tunicamycin; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00007182 fbxb-119 Enriched in SMBDL; SMBDR; SMBVL; and SMBVR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Mercuric Chloride; rotenone; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00007183 B0462.4 Enriched in ASHL; ASHR; XXXL; and XXXR based on single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including tryptophan; Mercuric Chloride; and sodium arsenite based on microarray and RNA-seq studies. WB:WBGene00007184 ctr-9 Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Cdc73/Paf1 complex. Is an ortholog of human CTR9 (CTR9 homolog, Paf1/RNA polymerase II complex component). WB:WBGene00007185 nlp-36 Expressed in head and tail. WB:WBGene00007186 B0464.6 Predicted to be located in membrane. Is an ortholog of human TMEM209 (transmembrane protein 209). WB:WBGene00007187 tag-342 Enables calmodulin binding activity. Predicted to be involved in positive regulation of DNA-templated transcription and transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human SUPT3H (SPT3 homolog, SAGA and STAGA complex component). WB:WBGene00007188 B0464.9 Predicted to enable protein C-terminal methylesterase activity and protein phosphatase 2A binding activity. Is an ortholog of human PPME1 (protein phosphatase methylesterase 1). WB:WBGene00007189 pigm-1 Predicted to enable mannosyltransferase activity. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of glycosylphosphatidylinositol-mannosyltransferase I complex. Is an ortholog of human PIGM (phosphatidylinositol glycan anchor biosynthesis class M). WB:WBGene00007190 rmd-3 Predicted to enable microtubule binding activity. Predicted to be located in mitochondrion; mitotic spindle pole; and spindle microtubule. Is an ortholog of human RMDN3 (regulator of microtubule dynamics 3). WB:WBGene00007191 lgc-20 Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00007192 nduf-11 Enriched in OLL; PVD; and germ line based on proteomic; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on proteomic; tiling array; RNA-seq; and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00007193 B0491.6 Predicted to enable helicase activity. WB:WBGene00007194 dph-5 Predicted to enable diphthine synthase activity. Predicted to be involved in methylation and peptidyl-diphthamide biosynthetic process from peptidyl-histidine. Is an ortholog of human DPH5 (diphthamide biosynthesis 5). WB:WBGene00007195 thoc-7 Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Predicted to be part of THO complex part of transcription export complex. Is an ortholog of human THOC7 (THO complex subunit 7). WB:WBGene00007196 B0513.4 Enriched in several structures, including ABalaapppa; ABalapaapa; germ line; gonadal sheath cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including hydrogen sulfide; Alovudine; and Zidovudine based on microarray; RNA-seq; and proteomic studies. WB:WBGene00007197 prdh-1 Predicted to enable FAD binding activity and proline dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Predicted to be located in mitochondrion. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in hyperprolinemia type 1 and schizophrenia 4. Is an ortholog of human PRODH (proline dehydrogenase 1). WB:WBGene00007198 B0513.6 Enriched in germ line and sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00007199 B0513.7 Is affected by several genes including daf-16; daf-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00007200 vamp-8 Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in exocytosis and vesicle fusion. Predicted to be located in membrane. Predicted to be part of SNARE complex. Is an ortholog of human VAMP8 (vesicle associated membrane protein 8). WB:WBGene00007201 exos-4.1 Predicted to enable RNA binding activity. Predicted to be involved in RNA metabolic process. Predicted to be located in nucleolus. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Is an ortholog of human EXOSC4 (exosome component 4). WB:WBGene00007202 B0564.2 Predicted to enable dioxygenase activity. Predicted to be located in nucleus. Is an ortholog of human ALKBH6 (alkB homolog 6). WB:WBGene00007203 best-1 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). WB:WBGene00007204 best-2 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). WB:WBGene00007205 B0564.5 No description available WB:WBGene00007206 B0564.6 Enriched in head mesodermal cell; muscle cell; and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; skn-1; and clk-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily and Leucine-rich repeat, cysteine-containing subtype. WB:WBGene00007207 fask-1 Predicted to enable RNA binding activity. Predicted to be involved in mitochondrial RNA processing and regulation of mitochondrial mRNA stability. Predicted to be located in mitochondrial matrix and ribonucleoprotein granule. Is an ortholog of human TBRG4 (transforming growth factor beta regulator 4). WB:WBGene00007208 B0564.9 Enriched in head mesodermal cell; muscle cell; and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; skn-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including aldicarb; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily and Leucine-rich repeat, cysteine-containing subtype. WB:WBGene00007209 BE10.1 Enriched in germ line; neurons; and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00007210 agmo-1 Predicted to enable glyceryl-ether monooxygenase activity. Predicted to be involved in membrane lipid metabolic process. Predicted to be located in endoplasmic reticulum. Expressed in hyp7 syncytium and seam cell. Is an ortholog of human AGMO (alkylglycerol monooxygenase). WB:WBGene00007211 BE10.3 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. WB:WBGene00007212 BE10.4 Enriched in germ line; hypodermis; neuronal sheath cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including mianserin; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007213 C01A2.1 Predicted to be located in membrane. WB:WBGene00007214 C01A2.2 Predicted to be located in membrane. WB:WBGene00007215 oxa-1 Predicted to enable membrane insertase activity. Predicted to be involved in protein insertion into mitochondrial inner membrane from matrix. Located in mitochondrion. Expressed in body wall musculature and pharyngeal muscle cell. Is an ortholog of human OXA1L (OXA1L mitochondrial inner membrane protein). WB:WBGene00007216 C01A2.4 Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Predicted to be located in multivesicular body. Predicted to be part of ESCRT III complex. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and chromosome 3-linked frontotemporal dementia. Is an ortholog of human CHMP2B (charged multivesicular body protein 2B). WB:WBGene00007217 tads-1 Predicted to be involved in mitotic DNA replication termination. Predicted to be located in nucleus. Is an ortholog of human RTF2 (replication termination factor 2). WB:WBGene00007218 C01A2.6 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Sodium Chloride; allantoin; and Psoralens based on RNA-seq studies. WB:WBGene00007219 nlp-38 Predicted to be involved in chemotaxis and neuropeptide signaling pathway. Predicted to be located in extracellular region. WB:WBGene00007220 C01B9.1 Enriched in body wall musculature; g2; intestine; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and Phosphorylation site. WB:WBGene00007221 cpna-3 Predicted to enable calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion. Predicted to be located in plasma membrane. WB:WBGene00007222 gldi-10 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. WB:WBGene00007223 znf-706 Predicted to be located in cytoplasm and nucleus. Is an ortholog of human ZNF706 (zinc finger protein 706). WB:WBGene00007224 C01G6.2 Predicted to be located in membrane. WB:WBGene00007225 C01G6.3 Enriched in several structures, including ABplpppapa; germ line; interfacial epithelial cell; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including Heme; Ethanol; and methylmercury hydroxide based on microarray; RNA-seq; and proteomic studies. WB:WBGene00007226 C01G6.4 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be part of ubiquitin ligase complex. Expressed in body wall musculature; intestine; neurons; and non-striated muscle. Is an ortholog of human RNF11 (ring finger protein 11). WB:WBGene00007227 gldi-3 Predicted to be involved in regulation of gene expression. Predicted to be located in nucleus. Is an ortholog of human TCF19 (transcription factor 19). WB:WBGene00007228 acs-7 Enables medium-chain fatty acid-CoA ligase activity. Involved in ascaroside biosynthetic process. Located in peroxisome. Expressed in intestinal cell. WB:WBGene00007229 C01G6.9 Enriched in germline precursor cell; hypodermis; and tail hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; methylmercuric chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00007230 C01G10.1 Predicted to be located in membrane. WB:WBGene00007231 C01G10.4 Enriched in accessory cell and male-specific anatomical entity based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including methylmercuric chloride; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00007232 C01G10.5 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; marginal cell; and mechanosensory neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by twenty-one chemicals including tryptophan; Tunicamycin; and bisphenol A based on microarray and RNA-seq studies. WB:WBGene00007233 C01G10.6 Enriched in ABalaaaala; ABalaapaaa; and mc3 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Sodium Chloride; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00007234 C01G10.7 Predicted to enable magnesium ion binding activity. Predicted to be involved in oxaloacetate metabolic process. Expressed in head. Is an ortholog of human CLYBL (citramalyl-CoA lyase). WB:WBGene00007235 ahsa-1 Predicted to enable ATPase activator activity. Predicted to be involved in protein folding. Predicted to be located in cytosol. Is an ortholog of human AHSA1 (activator of HSP90 ATPase activity 1). WB:WBGene00007236 C01G10.9 Predicted to enable S-methyl-5-thioribose-1-phosphate isomerase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human MRI1 (methylthioribose-1-phosphate isomerase 1). WB:WBGene00007237 C01G10.10 Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to be located in mitochondrion. Is an ortholog of human OSGEPL1 (O-sialoglycoprotein endopeptidase like 1). WB:WBGene00007238 C01G10.13 Is affected by Atrazine based on microarray studies. WB:WBGene00007239 C01G10.14 Predicted to be located in cytoskeleton. WB:WBGene00007240 C01G10.15 Enriched in several structures, including ABarpapaapp; ABplaaaaapp; AVA; MSaapaapa; and accessory cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Sodium Chloride; antimycin; and Ag nanoparticles based on RNA-seq studies. WB:WBGene00007241 txt-12 Enriched in marginal cell and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and lin-15B based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq studies. WB:WBGene00007242 madf-5 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. WB:WBGene00007243 nspb-7 Enriched in arcade cell; hypodermis; and pharyngeal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including D-glucose; Cry5B; and cholesterol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00007244 C01G12.3 Enriched in amphid sheath cell; germ line; pharyngeal cell; pharyngeal-intestinal valve; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00007245 C01G12.5 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00007246 nspb-10 Enriched in AVBL; AVBR; and arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and let-7 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including multi-walled carbon nanotube; Neurotoxins; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00007247 C01G12.7 Predicted to be located in membrane. WB:WBGene00007248 catp-4 Predicted to enable P-type sodium:potassium-exchanging transporter activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. WB:WBGene00007249 C01G12.9 Predicted to be located in membrane. WB:WBGene00007250 nspb-8 Enriched in MSpaaapa; arcade cell; pharyngeal cell; and pharyngeal-intestinal valve based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; D-glucose; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00007251 nspb-9 Enriched in several structures, including MSaaaaapa; MSaapapa; MSpapapa; pharyngeal cell; and pharyngeal-intestinal valve based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00007252 mlt-2 Involved in ecdysis, collagen and cuticulin-based cuticle. Predicted to be located in ciliary inversin compartment. Expressed in hyp7 syncytium. WB:WBGene00007253 C01H6.3 Enriched in neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007254 C01H6.4 Predicted to enable flavin adenine dinucleotide binding activity and monooxygenase activity. Predicted to be located in cytosol. WB:WBGene00007255 cnnm-4 Predicted to enable transmembrane transporter activity. Involved in determination of adult lifespan and positive regulation of gonad development. Predicted to be located in plasma membrane. WB:WBGene00007256 swsn-9 Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in muscle cell; pharynx; and somatic gonad. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in acute myeloid leukemia; carcinoma (multiple); and glioblastoma. Is an ortholog of human BRD7 (bromodomain containing 7). WB:WBGene00007257 C01H6.8 Predicted to be located in membrane. WB:WBGene00007258 hasp-1 Enables G-protein alpha-subunit binding activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. Expressed in PHB; PVT; head neurons; intestine; and seam cell. Is an ortholog of human HASPIN (histone H3 associated protein kinase). WB:WBGene00007259 C02B4.3 Is affected by several genes including daf-12; eat-2; and eri-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine; fluoranthene; and paraquat based on microarray studies. WB:WBGene00007260 olrn-1 Involved in olfactory learning. Predicted to be located in plasma membrane. Expressed in head neurons; pharyngeal cell; and rectal gland cell. WB:WBGene00007261 lron-3 Predicted to be located in membrane. Is an ortholog of human TPBG (trophoblast glycoprotein). WB:WBGene00007262 jud-4 Expressed in hypodermis and vulval muscle. WB:WBGene00007264 C02F4.4 Enriched in ASER; PLM; germline precursor cell; hypodermis; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including Ethanol; methylmercury hydroxide; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00007265 C02F4.5 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and lin-39 based on RNA-seq and microarray studies. WB:WBGene00007266 C03A3.1 Predicted to be located in membrane. WB:WBGene00007267 C03A3.2 Predicted to be located in membrane. Is an ortholog of human TMEM104 (transmembrane protein 104). WB:WBGene00007268 C03A3.3 Expressed in touch receptor neurons. Human MBLAC2 enables beta-lactamase activity and palmitoyl-CoA hydrolase activity. Is predicted to encode a protein with the following domains: Metallo-beta-lactamase; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; and Metallo-beta-lactamase superfamily. Is an ortholog of human MBLAC2 (metallo-beta-lactamase domain containing 2). WB:WBGene00007269 C03C10.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00007270 rei-1 Enables guanyl-nucleotide exchange factor activity. Involved in protein localization to Golgi membrane. Located in Golgi trans cisterna membrane. Is an ortholog of human SH3BP5 (SH3 domain binding protein 5) and SH3BP5L (SH3 binding domain protein 5 like). WB:WBGene00007271 C03C10.5 Enriched in several structures, including ABalpppappp; ABalppppaa; AUA; SAA; and amphid neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00007273 C03C10.7 Enriched in AFD; CEM; HOB; IL2 neuron; and ray neuron type B based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on microarray and RNA-seq studies. Is affected by eight chemicals including mianserin; multi-walled carbon nanotube; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00007274 C03C11.1 Predicted to be part of collagen trimer. WB:WBGene00007275 C03D6.1 Predicted to enable nucleic acid binding activity. Expressed in tail. WB:WBGene00007277 asfl-1 Predicted to enable histone binding activity. Involved in DNA replication and multicellular organismal reproductive process. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ASF1A (anti-silencing function 1A histone chaperone). WB:WBGene00007278 lab-1 Enables protein phosphatase 1 binding activity. Involved in meiotic sister chromatid cohesion and regulation of protein localization to nucleus. Located in condensed chromosome and nucleus. WB:WBGene00007279 C03E10.1 Predicted to be located in membrane. WB:WBGene00007280 C03E10.2 No description available WB:WBGene00007281 C03E10.3 Predicted to be located in membrane. WB:WBGene00007282 clec-223 Expressed in spermatheca. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00007283 clec-222 Enriched in germ line based on proteomic and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-four chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: C-type lectin fold. WB:WBGene00007284 C03H12.1 Predicted to be involved in cell migration; positive regulation of canonical Wnt signaling pathway; and regulation of protein localization to membrane. Predicted to be located in cell surface. Is an ortholog of human TXNDC11 (thioredoxin domain containing 11). WB:WBGene00007285 C04A11.1 Predicted to be located in membrane. WB:WBGene00007286 C04A11.2 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapapapa; AUA; and ciliated neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including methylmercury hydroxide; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007287 gck-4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cytoplasm. Expressed in head and tail. Is an ortholog of human SLK (STE20 like kinase) and STK10 (serine/threonine kinase 10). WB:WBGene00007288 C04A11.5 Enriched in excretory system; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including D-glucose; stavudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00007289 C04B4.1 Predicted to be involved in negative regulation of gene expression. Predicted to be located in cytoplasm. WB:WBGene00007290 C04B4.2 Predicted to be involved in negative regulation of gene expression. Predicted to be located in cytoplasm. Expressed in head. WB:WBGene00007291 lips-2 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00007292 C04B4.4 Predicted to be involved in negative regulation of gene expression. Predicted to be located in cytoplasm. WB:WBGene00007293 C04B4.5 Is affected by cyc-1; rsr-2; and lpd-3 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00007294 C04B4.6 Is affected by rsr-2 and lag-1 based on tiling array and RNA-seq studies. Is affected by Atrazine and dibromoacetic acid based on microarray studies. Is predicted to encode a protein with the following domain: Ubiquitin-like domain superfamily. WB:WBGene00007295 C04C11.1 Enriched in cephalic sheath cell; head mesodermal cell; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: CAP domain; Cysteine-rich secretory protein family; and CAP superfamily. WB:WBGene00007296 arrd-25 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. WB:WBGene00007297 vsra-1 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Involved in IRE1-mediated unfolded protein response. WB:WBGene00007298 C04F12.2 No description available WB:WBGene00007299 C04F12.5 Enriched in several structures, including germ line; germline precursor cell; intestine; neurons; and ventral nerve cord based on Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00007300 C04F12.6 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including age-1; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; cholesterol; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00007301 C04F12.7 Predicted to be located in membrane. WB:WBGene00007302 C04F12.8 Predicted to enable protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in dephosphorylation. Located in striated muscle myosin thick filament. Is an ortholog of human DUSP14 (dual specificity phosphatase 14); DUSP18 (dual specificity phosphatase 18); and DUSP21 (dual specificity phosphatase 21). WB:WBGene00007303 rnh-1.3 Predicted to enable RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer. WB:WBGene00007304 ttr-39 Predicted to be located in cell surface and extracellular region. WB:WBGene00007305 ttbk-5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Expressed in ASIL; ASIR; amphid neurons; and neurons. WB:WBGene00007306 C04G2.5 Enriched in NSM; g2L; g2R; germ line; and in male based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including Heme; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00007307 spch-1 Involved in male meiotic nuclear division. Part of chromatin. Expressed in sperm. WB:WBGene00007308 nsph-3.2 Enriched in several structures, including ABplppaaaap; AVB; amphid sheath cell; germ line; and sperm based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; proteomic; and RNA-seq studies. Is affected by thirty-nine chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Cytosolic motility protein. WB:WBGene00007309 C04G2.10 Predicted to enable histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. WB:WBGene00007310 irld-21 Enriched in several structures, including ASJ; Z1.p; intestine; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; mex-3; and mex-1 based on tiling array and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00007311 C04H4.1 Enriched in neurons based on tiling array and RNA-seq studies. Is affected by several genes including csr-1; mir-34; and etr-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00007312 C04H5.1 Predicted to enable protein heterodimerization activity. Predicted to be involved in rRNA (guanine-N7)-methylation and tRNA methylation. Is an ortholog of human TRMT112 (tRNA methyltransferase activator subunit 11-2). WB:WBGene00007313 clec-147 Enriched in several structures, including germ line; intestine; male distal tip cell; neurons; and retrovesicular ganglion based on microarray and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including methylmercuric chloride; rotenone; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00007314 gcy-29 Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Expressed in AVK and amphid neurons. WB:WBGene00007315 C04H5.7 Enriched in AVE; Z1.p; Z4.a; germ line; and gonad based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Lithium Chloride; Heme; and diallyl trisulfide based on microarray and RNA-seq studies. WB:WBGene00007316 nlp-41 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00007317 C05A9.2 Predicted to be located in membrane. WB:WBGene00007319 C05B5.1 Enriched in ABalappaap; ABplppppap; ABprppppap; and g1 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by stavudine; dafa#1; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007320 C05B5.2 Predicted to be located in membrane. WB:WBGene00007321 C05B5.4 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalapaaaa; AVE; and interfacial epithelial cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Uncharacterized protein C05B5.4-like. WB:WBGene00007322 C05B5.5 Enriched in Z1.p; Z4.a; germ line; intestine; and male distal tip cell based on proteomic; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including stavudine; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00007323 fbxa-155 Enriched in coelomocyte; germ line; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including tryptophan; methylmercury hydroxide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; Mos1 transposase, HTH domain; HTH domain in Mos1 transposase; and FTH domain. WB:WBGene00007324 C05B5.8 Predicted to be located in membrane. WB:WBGene00007325 C05C9.1 Predicted to enable lipid binding activity. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in Crohn's disease and severe acute respiratory syndrome. Is an ortholog of human BPI (bactericidal permeability increasing protein); BPIFC (BPI fold containing family C); and LBP (lipopolysaccharide binding protein). WB:WBGene00007326 C05C9.2 Enriched in neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; pgl-1; and alg-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00007327 C05C9.3 Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of mediator complex. WB:WBGene00007328 pho-10 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00007329 C05C10.2 Predicted to enable RNA binding activity. WB:WBGene00007330 C05C10.3 Predicted to enable succinyl-CoA:3-oxo-acid CoA-transferase activity. Predicted to be involved in cellular ketone body metabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder. Is an ortholog of human OXCT1 (3-oxoacid CoA-transferase 1) and OXCT2 (3-oxoacid CoA-transferase 2). WB:WBGene00007331 pho-11 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00007332 C05C10.5 Expressed in germ line. WB:WBGene00007333 ufd-3 Predicted to enable ubiquitin binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and ubiquitin recycling. Located in cytoplasm. Used to study amyotrophic lateral sclerosis. Is an ortholog of human PLAA (phospholipase A2 activating protein). WB:WBGene00007334 C05C10.7 Predicted to be located in membrane. WB:WBGene00007335 C05C12.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00007336 C05C12.4 Predicted to be located in membrane. WB:WBGene00007337 C05C12.5 Enriched in germ line; neurons; sperm; and in male based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by twenty-six chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00007338 C05C12.6 Predicted to be located in lysosomal membrane. WB:WBGene00007339 C05D12.1 Predicted to be located in membrane. Is an ortholog of human FRRS1 (ferric chelate reductase 1). WB:WBGene00007340 C05D12.2 Enriched in head mesodermal cell and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00007341 C05D12.4 Enriched in AVJL; AVJR; OLL; PVD; and intestine based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00007342 C05D12.5 Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00007343 gmap-2 Enriched in several structures, including XXX cell; germline precursor cell; interfacial epithelial cell; neurons; and rectal gland cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; RNA-seq; and microarray studies. Is affected by seventeen chemicals including 1-methylnicotinamide; D-glucose; and Neurotoxins based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: GM2-AP, lipid-recognition domain superfamily. WB:WBGene00007344 gmap-3 Enriched in cholinergic neurons; hypodermis; rectal epithelial cell; and rectal gland cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; tiling array; microarray; and RNA-seq studies. Is affected by twenty-nine chemicals including Heme; aldicarb; and 1-methylnicotinamide based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: GM2-AP, lipid-recognition domain superfamily. WB:WBGene00007345 C05E7.3 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppppapa; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007346 frpr-2 Predicted to be located in membrane. WB:WBGene00007347 C05G5.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in plasma membrane. Expressed in head neurons; nerve ring; tail neurons; and ventral nerve cord. Is an ortholog of human SLC49A3 (solute carrier family 49 member 3). WB:WBGene00007348 C05G5.2 Enriched in several structures, including MSpaaaaa; MSpaaapa; g2; ganglia; and rectal epithelial cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Zidovudine; paraquat; and resveratrol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007349 C05G5.3 Predicted to be located in membrane. Is an ortholog of human MXRA7 (matrix remodeling associated 7). WB:WBGene00007350 sucl-1 Predicted to enable succinate-CoA ligase (ADP-forming) activity and succinate-CoA ligase (GDP-forming) activity. Predicted to be involved in tricarboxylic acid cycle. Located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 9. Is an ortholog of human SUCLG1 (succinate-CoA ligase GDP/ADP-forming subunit alpha). WB:WBGene00007351 C05G5.5 Predicted to enable metalloendopeptidase activity. Predicted to be involved in negative regulation of Wnt signaling pathway and proteolysis. Predicted to be located in membrane. Is an ortholog of human TRABD2A (TraB domain containing 2A) and TRABD2B (TraB domain containing 2B). WB:WBGene00007352 cdc-48.1 Enables ATP hydrolysis activity and identical protein binding activity. Involved in several processes, including ER-associated misfolded protein catabolic process; determination of adult lifespan; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in nucleoplasm and perinuclear region of cytoplasm. Part of VCP-NPL4-UFD1 AAA ATPase complex. Expressed in several structures, including body wall musculature; germ line; and gonad. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2Y; frontotemporal dementia and/or amyotrophic lateral sclerosis-6; and inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 1. Is an ortholog of human VCP (valosin containing protein). WB:WBGene00007353 txt-13 Predicted to be located in membrane. WB:WBGene00007354 C06A1.3 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. Expressed in XXXL and XXXR. WB:WBGene00007355 rpb-6 Predicted to enable DNA binding activity and DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Involved in developmental process and reproduction. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Is an ortholog of human POLR2F (RNA polymerase II, I and III subunit F). WB:WBGene00007356 C06A1.6 Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Neurotoxins; Testosterone; and resveratrol based on microarray studies. WB:WBGene00007357 C06A12.3 Predicted to enable kinase regulator activity and protein kinase A binding activity. Predicted to be involved in regulation of canonical Wnt signaling pathway. Predicted to be located in cytoplasm. Is an ortholog of human GSKIP (GSK3B interacting protein). WB:WBGene00007358 lact-6 Enriched in Y cell and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including let-60; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercury hydroxide; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Beta-lactamase; Beta-lactamase/transpeptidase-like; and Beta-lactamase-related. WB:WBGene00007359 C06A12.8 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; csr-1; and nhr-114 based on microarray; tiling array; and RNA-seq studies. WB:WBGene00007360 C06B3.1 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00007361 oac-3 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00007362 cyp-35C1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2E1 (cytochrome P450 family 2 subfamily E member 1); and CYP2F1 (cytochrome P450 family 2 subfamily F member 1). WB:WBGene00007363 stdh-1 Predicted to enable oxidoreductase activity. Predicted to be involved in fatty acid elongation. Predicted to be located in endoplasmic reticulum. Expressed in head and tail. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). WB:WBGene00007364 stdh-3 Predicted to enable oxidoreductase activity. Predicted to be involved in fatty acid elongation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). WB:WBGene00007365 C06B3.6 Enriched in several structures, including ALA; PVT; coelomocyte; head mesodermal cell; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by twenty-six chemicals including diallyl trisulfide; Ethanol; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00007366 C06B3.7 Enriched in intestine; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twenty-seven chemicals including Heme; Nitric Oxide; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00007367 nhr-150 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00007368 C06B8.2 Enriched in OLL; PVD; body wall musculature; head mesodermal cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1647) and Protein of unknown function DUF1647. WB:WBGene00007369 C06B8.3 Enriched in NSM based on tiling array studies. Is affected by clk-1 and drh-3 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and Enoyl-(Acyl carrier protein) reductase. WB:WBGene00007370 str-264 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00007371 C06B8.5 No description available WB:WBGene00007372 C06B8.7 Predicted to be involved in endocytosis. Predicted to be located in membrane. WB:WBGene00007373 C06B8.11 Enriched in NSM based on tiling array studies. WB:WBGene00007374 C06C3.3 Predicted to be involved in intracellular signal transduction. Predicted to be located in microtubule and microtubule organizing center. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; autosomal recessive nonsyndromic deafness 66; and dyslexia. Is an ortholog of human DCDC2 (doublecortin domain containing 2). WB:WBGene00007375 C06C3.4 Expressed in hypodermis. WB:WBGene00007376 C06C3.5 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including age-1; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007377 C06C3.7 Enriched in ABaraapapp; ABaraapppp; AFD; body wall muscle cell; and pharyngeal muscle cell based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00007378 lido-17 Predicted to enable ATP-dependent peptidase activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in nucleus. WB:WBGene00007379 C06C6.1 Enriched in NSM and neurons based on tiling array studies. Is affected by several genes including daf-2; mex-1; and mir-34 based on microarray and RNA-seq studies. Is affected by resveratrol; tetrabromobisphenol A; and Sirolimus based on microarray studies. WB:WBGene00007380 C06C6.6 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on RNA-seq; microarray; and proteomic studies. Is affected by six chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00007381 C06C6.7 Predicted to be located in membrane. WB:WBGene00007382 C06C6.8 Predicted to be located in membrane. WB:WBGene00007383 C06C6.9 Predicted to be located in membrane. WB:WBGene00007384 swt-3 Predicted to enable sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport. Predicted to be located in Golgi membrane. Expressed in Z1; Z4; and spermatheca. Is an ortholog of human SLC50A1 (solute carrier family 50 member 1). WB:WBGene00007385 atp-5 Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase, stator stalk. Is an ortholog of human ATP5PD (ATP synthase peripheral stalk subunit d). WB:WBGene00007386 C06H2.2 Predicted to enable lipid binding activity. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 2. Is an ortholog of human STARD7 (StAR related lipid transfer domain containing 7). WB:WBGene00007387 jmjd-5 Predicted to enable histone H3K36 demethylase activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process and chromatin remodeling. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human KDM8 (lysine demethylase 8). WB:WBGene00007388 folt-1 Predicted to enable folic acid binding activity and vitamin transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Expressed in head; head muscle; and tail. Human ortholog(s) of this gene implicated in several diseases, including biotin-responsive basal ganglia disease; cleft lip; and dextro-looped transposition of the great arteries. Is an ortholog of human SLC19A3 (solute carrier family 19 member 3). WB:WBGene00007389 glb-3 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00007390 lmtr-3 Predicted to be involved in cellular response to amino acid stimulus and positive regulation of TOR signaling. Predicted to be part of Ragulator complex. Is an ortholog of human LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3). WB:WBGene00007391 C06H2.7 Enriched in PLML; PLMR; excretory cell; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; Zidovudine; and tert-Butylhydroperoxide based on RNA-seq and microarray studies. WB:WBGene00007392 fbxa-156 Enriched in head mesodermal cell; intestine; and lateral ganglion based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including 1-methylnicotinamide; D-glucopyranose; and 4-bromodiphenyl ether based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00007393 fbxa-157 Enriched in AWC; DD neuron; head mesodermal cell; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Tunicamycin; levamisole; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00007394 C06H5.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00007395 dcar-1 Predicted to enable neuropeptide receptor activity. Involved in defense response to fungus and response to wounding. Located in apical plasma membrane and non-motile cilium. Expressed in PVQ; amphid neurons; hyp7 syncytium; and uterus. WB:WBGene00007396 rnp-9 Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Involved in several processes, including determination of adult lifespan; hyperosmotic response; and response to heat. Located in nucleus. Expressed in head neurons; spermatheca; tail neurons; and ventral nerve cord. WB:WBGene00007397 C07A4.2 Predicted to be located in extracellular space. WB:WBGene00007398 C07A4.3 Predicted to be located in extracellular space. WB:WBGene00007399 clec-162 Predicted to enable carbohydrate binding activity. Predicted to be located in extracellular region. WB:WBGene00007400 bud-31 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human BUD31 (BUD31 homolog). WB:WBGene00007401 C07A9.5 Predicted to enable metal ion binding activity. WB:WBGene00007402 ugt-60 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT2A2 (UDP glucuronosyltransferase family 2 member A2). WB:WBGene00007403 set-3 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Expressed in AB; Psub1; hypodermis; and intestine. Is an ortholog of human SMYD4 (SET and MYND domain containing 4). WB:WBGene00007404 best-5 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). WB:WBGene00007405 C07A9.9 Enriched in several structures, including ABalappaap; ABalpppppa; ABplapppapp; enteric muscle; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including 4-bromodiphenyl ether; Zidovudine; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00007406 C07A9.10 Is affected by several genes including sir-2.1; clk-1; and mex-3 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Tunicamycin; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00007407 C07B5.2 Enriched in PLML; PLMR; hypodermis; and intestine based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; multi-walled carbon nanotube; and allantoin based on microarray and RNA-seq studies. WB:WBGene00007408 C07B5.3 Enriched in ABalapppaa; neurons; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by six chemicals including nicotinic acid; Mercuric Chloride; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00007409 C07B5.4 Predicted to be involved in actomyosin contractile ring assembly; mitotic cytokinesis; and septin ring organization. Predicted to be located in actomyosin contractile ring. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human RTKN2 (rhotekin 2). WB:WBGene00007410 C07B5.6 Enriched in several structures, including ABplapapppp; ABprapapppp; Z1.p; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and lin-29 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00007411 C07C7.1 Predicted to be located in membrane. WB:WBGene00007412 stip-1 Predicted to enable nucleic acid binding activity. Predicted to be involved in spliceosomal complex disassembly. Predicted to be located in nucleus. Predicted to be part of U2-type post-mRNA release spliceosomal complex. Is an ortholog of human TFIP11 (tuftelin interacting protein 11). WB:WBGene00007413 pro-2 Predicted to enable histone binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and ribosomal large subunit biogenesis. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Noc1p-Noc2p complex and Noc2p-Noc3p complex. Is an ortholog of human NOC2L (NOC2 like nucleolar associated transcriptional repressor). WB:WBGene00007414 C07E3.3 Enriched in several structures, including ABarppaapp; ABarpppapp; excretory gland cell; head mesodermal cell; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including diallyl trisulfide; rotenone; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007415 C07E3.4 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00007416 ceh-57 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in amphid neurons; intestine; neuroblasts; and somatic nervous system. WB:WBGene00007417 ceh-58 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in neurons and somatic nervous system. WB:WBGene00007418 C07E3.8 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. WB:WBGene00007419 C07E3.9 Predicted to enable calcium ion binding activity and phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion; lipid catabolic process; and phospholipid metabolic process. Predicted to be located in extracellular region. Is an ortholog of human PLA2G1B (phospholipase A2 group IB). WB:WBGene00007420 C07E3.10 Predicted to be located in membrane. WB:WBGene00007421 C07H4.1 Predicted to be located in membrane. WB:WBGene00007422 ugt-17 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00007423 C08B6.2 Is affected by several genes including skn-1; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including tryptophan; 1-methylnicotinamide; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00007424 C08B6.3 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00007425 cht-5 Predicted to enable chitinase activity. Predicted to be involved in cell wall macromolecule catabolic process and chitin catabolic process. Expressed in amphid neurons and hypodermis. WB:WBGene00007426 C08B6.5 Predicted to be located in membrane. WB:WBGene00007427 C08B6.6 Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including methylmercuric chloride; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00007428 wdr-20 Involved in positive regulation of locomotion involved in locomotory behavior; positive regulation of macromolecule metabolic process; and positive regulation of protein localization to cell surface. Expressed in head neurons; tail neurons; and ventral nerve cord. Is an ortholog of human DMWD (DM1 locus, WD repeat containing) and WDR20 (WD repeat domain 20). WB:WBGene00007429 C08B6.8 Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to be involved in nucleic acid metabolic process and obsolete RNA phosphodiester bond hydrolysis, exonucleolytic. Predicted to be located in mitochondrion. Is an ortholog of human REXO2 (RNA exonuclease 2). WB:WBGene00007430 C08B6.10 Enriched in RICL; RICR; germ line; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Cry5B; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007431 C08B6.11 Predicted to be located in membrane. WB:WBGene00007432 srxa-18 Predicted to be located in membrane. WB:WBGene00007433 swsn-7 Predicted to enable DNA binding activity. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 6 and gastrointestinal system cancer (multiple). Is an ortholog of human ARID2 (AT-rich interaction domain 2). WB:WBGene00007434 arp-6 Predicted to enable nucleosome binding activity. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of Swr1 complex. Is an ortholog of human ACTR6 (actin related protein 6). WB:WBGene00007435 algn-6 Predicted to enable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ic. Is an ortholog of human ALG6 (ALG6 alpha-1,3-glucosyltransferase). WB:WBGene00007436 C08B11.9 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalpapaap; GLR; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by eight chemicals including rotenone; stavudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF2452 and Protein of unknown function (DUF2452). Is an ortholog of human C1orf50 (chromosome 1 open reading frame 50). WB:WBGene00007437 C08E8.1 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00007438 C08E8.2 Predicted to enable hydrolase activity. Predicted to be involved in biosynthetic process. Is an ortholog of human APMAP (adipocyte plasma membrane associated protein). WB:WBGene00007439 C08E8.3 Enriched in hypodermis and muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including multi-walled carbon nanotube; bisphenol A; and procyanidin based on RNA-seq and microarray studies. WB:WBGene00007440 C08E8.4 Involved in innate immune response. WB:WBGene00007441 C08E8.5 Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. WB:WBGene00007442 C08E8.6 Enriched in ASER and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by adr-1 and mes-4 based on RNA-seq studies. Is affected by tryptophan based on microarray studies. WB:WBGene00007443 pfd-1 Predicted to enable protein folding chaperone and unfolded protein binding activity. Involved in gonad development. Located in cytoplasm. Expressed in head muscle; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human PFDN1 (prefoldin subunit 1). WB:WBGene00007444 C08F8.2 Predicted to enable DNA binding activity; DNA helicase activity; and RNA helicase activity. Predicted to be involved in DNA duplex unwinding; RNA catabolic process; and mitochondrial RNA 3'-end processing. Predicted to be located in mitochondrial matrix. Predicted to be part of mitochondrial degradosome. Is an ortholog of human SUPV3L1 (Suv3 like RNA helicase). WB:WBGene00007445 C08F8.3 Enriched in germ line; germline precursor cell; head mesodermal cell; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including manganese chloride; Alovudine; and stavudine based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007446 mboa-4 Predicted to enable acyltransferase activity. Predicted to be involved in lipid modification. Predicted to be located in membrane. Is an ortholog of human MBOAT1 (membrane bound O-acyltransferase domain containing 1) and MBOAT2 (membrane bound O-acyltransferase domain containing 2). WB:WBGene00007447 fbxb-9 Enriched in ABplpppppp and ABprpppppp based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00007448 C08F8.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00007449 C08F8.9 Enriched in ASER; PLM; germ line; intestine; and male-specific anatomical entity based on RNA-seq and microarray studies. Is affected by several genes including daf-2; sir-2.1; and npr-1 based on RNA-seq and microarray studies. Is affected by six chemicals including D-glucose; stavudine; and Rifampin based on RNA-seq studies. WB:WBGene00007450 C08F11.1 Enriched in AMshL; AMshR; amphid sheath cell; excretory duct; and excretory pore based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and aak-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; D-glucose; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007451 C08F11.2 Is affected by rsr-2 based on tiling array studies. Is affected by resveratrol and cadmium based on microarray studies. WB:WBGene00007452 C08F11.3 Predicted to be located in membrane. WB:WBGene00007453 fbxa-98 Enriched in AVA; head mesodermal cell; intestine; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; levamisole; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00007454 C08F11.7 Enriched in AVA; coelomocyte; and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; nicotinic acid; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00007455 ugt-22 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00007456 srz-29 Predicted to be located in membrane. WB:WBGene00007457 C08F11.10 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily. WB:WBGene00007458 ule-4 Predicted to be located in extracellular region. WB:WBGene00007459 C08F11.12 Predicted to be located in extracellular region. WB:WBGene00007460 C08F11.13 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. WB:WBGene00007461 C08F11.14 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and npr-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00007462 ctsa-3.2 Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Human ortholog(s) of this gene implicated in galactosialidosis. Is an ortholog of human CTSA (cathepsin A). WB:WBGene00007463 vgln-1 Predicted to enable mRNA binding activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of polysome. Is an ortholog of human HDLBP (high density lipoprotein binding protein). WB:WBGene00007464 algn-8 Predicted to enable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ih and polycystic liver disease. Is an ortholog of human ALG8 (ALG8 alpha-1,3-glucosyltransferase). WB:WBGene00007465 chil-1 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00007466 chil-2 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. WB:WBGene00007467 chil-3 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00007468 C08H9.8 Is affected by clk-1; daf-2; and pals-25 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00007469 chil-4 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00007470 chil-5 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00007471 chil-6 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00007472 chil-7 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00007473 chil-8 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. WB:WBGene00007474 C08H9.15 Predicted to be located in membrane. WB:WBGene00007475 B0285.t1 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00007476 C09E9.1 Predicted to be involved in regulation of mitochondrial membrane potential. Predicted to be located in mitochondrion. Expressed in tail. Is an ortholog of human TUSC2 (tumor suppressor 2, mitochondrial calcium regulator). WB:WBGene00007478 C09F9.1 Predicted to be located in membrane. WB:WBGene00007479 C09F9.2 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region and membrane. WB:WBGene00007480 glna-1 Predicted to enable glutaminase activity. Predicted to be involved in glutamate biosynthetic process and glutamine catabolic process. Predicted to be located in mitochondrion. Expressed in several structures, including mc2; mc3DL; mc3DR; mc3V; and neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 71 and lymphangioleiomyomatosis. Is an ortholog of human GLS (glutaminase). WB:WBGene00007481 C09F9.4 Is affected by several genes including daf-16; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercury hydroxide; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007482 C09F12.2 Predicted to be located in membrane. WB:WBGene00007483 C09F12.3 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00007484 C09G1.2 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00007485 C09G1.3 Enriched in ABalapppaa and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eight chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00007486 C09G1.4 Predicted to be involved in centrosome cycle. WB:WBGene00007487 C09G1.5 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00007488 dph-2 Predicted to enable 4 iron, 4 sulfur cluster binding activity. Predicted to contribute to 2-(3-amino-3-carboxypropyl)histidine synthase activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine. Predicted to be located in protein-containing complex. Is an ortholog of human DPH2 (diphthamide biosynthesis 2). WB:WBGene00007489 C09G5.7 Enriched in several structures, including ABalapapap; ABalapppap; ABplpaaapp; PLM; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and pie-1 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including methylmercuric chloride; manganese chloride; and mianserin based on microarray and RNA-seq studies. WB:WBGene00007490 mks-5 Involved in several processes, including non-motile cilium assembly; protein localization to cilium; and protein to membrane docking. Located in ciliary basal body and ciliary transition zone. Expressed in chemosensory neurons and ciliated neurons. Used to study ciliopathy. Human ortholog(s) of this gene implicated in several diseases, including Joubert syndrome 7; Leber hereditary optic neuropathy; and retinal disease (multiple). Is an ortholog of human RPGRIP1L (RPGRIP1 like). WB:WBGene00007492 C09G9.1 Enriched in several structures, including germ line; germline precursor cell; mechanosensory neurons; rectal epithelium; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00007493 npp-23 Located in kinetochore. Part of nuclear pore. Is an ortholog of human NUP43 (nucleoporin 43). WB:WBGene00007494 C09G9.3 Enriched in NSM; PLM; anterior ganglion; and arc ant V based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and glycine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00007495 C09G9.5 Predicted to be located in membrane. WB:WBGene00007496 npax-4 Predicted to enable DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Expressed in body wall musculature and pseudocoelom. WB:WBGene00007497 C09G9.8 Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00007499 C09H10.5 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; AVK; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; glp-1; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by five chemicals including rotenone; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007500 nasp-1 Enables histone deacetylase binding activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in nucleoplasm. Expressed in metacorpus; pharynx; and terminal bulb. Human ortholog(s) of this gene implicated in ovarian cancer. Is an ortholog of human NASP (nuclear autoantigenic sperm protein). WB:WBGene00007502 glb-4 Predicted to enable heme binding activity and oxygen binding activity. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00007503 C09H10.9 Enriched in germ line; neurons; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00007504 nbs-1 Enriched in germ line; germline precursor cell; intestine; and muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including let-60; eat-2; and sek-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Forkhead-associated (FHA) domain; SMAD/FHA domain superfamily; and FHA domain. WB:WBGene00007505 pezo-1 Predicted to enable mechanosensitive monoatomic ion channel activity and monoatomic cation channel activity. Involved in flagellated sperm motility; positive regulation of brood size; and positive regulation of ovulation. Located in plasma membrane. Expressed in several structures, including germ line; gonad; pharynx; sperm; and ventral nerve cord. Used to study dehydrated hereditary stomatocytosis and distal arthrogryposis type 5. Human ortholog(s) of this gene implicated in dehydrated hereditary stomatocytosis 1; distal arthrogryposis (multiple); and hereditary lymphedema. Is an ortholog of human PIEZO1 (piezo type mechanosensitive ion channel component 1). WB:WBGene00007506 fbxc-58 Involved in innate immune response. Expressed in body wall musculature; neuronal sheath cell; pharyngeal-intestinal valve; and vulval muscle. WB:WBGene00007507 C10C5.3 Predicted to enable aminoacylase activity. Predicted to be involved in amino acid metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ACY1 (aminoacylase 1). WB:WBGene00007508 C10C5.4 Predicted to enable aminoacylase activity. Predicted to be involved in amino acid metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ACY1 (aminoacylase 1). WB:WBGene00007509 C10C5.5 Predicted to enable aminoacylase activity. Predicted to be involved in amino acid metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ACY1 (aminoacylase 1). WB:WBGene00007511 C10C5.7 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; unc-30; and prg-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007512 C10C6.3 Enriched in amphid sheath cell; germ line; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PH domain and PH_15 domain. WB:WBGene00007513 wht-2 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Expressed in head and intestinal cell. Human ortholog(s) of this gene implicated in several diseases, including gout; hematologic cancer (multiple); and toxic encephalopathy. Is an ortholog of human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)). WB:WBGene00007514 catp-8 Predicted to enable ATPase-coupled monoatomic cation transmembrane transporter activity; P-type ion transporter activity; and protein transporter activity. Acts upstream of with a positive effect on dendrite morphogenesis. Located in endoplasmic reticulum. Expressed in several structures, including HSN; body wall musculature; intestine; nervous system; and pharynx. Is an ortholog of human ATP13A1 (ATPase 13A1). WB:WBGene00007515 C10C6.7 Predicted to be located in membrane. Expressed in RIS; pharyngeal neurons; and sensory neurons. WB:WBGene00007516 gpx-5 Predicted to enable glutathione peroxidase activity. Involved in response to reactive oxygen species. Predicted to be located in extracellular space. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of human GPX3 (glutathione peroxidase 3) and GPX5 (glutathione peroxidase 5). WB:WBGene00007517 gpx-3 Predicted to enable glutathione peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of human GPX3 (glutathione peroxidase 3) and GPX5 (glutathione peroxidase 5). WB:WBGene00007518 del-8 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00007520 C11E4.6 Predicted to be located in cytoplasm. Is an ortholog of human ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A) and ANKS1B (ankyrin repeat and sterile alpha motif domain containing 1B). WB:WBGene00007521 C11E4.7 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00007522 C11E4.8 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00007523 C11G6.2 Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA helicase activity. Predicted to be involved in DNA duplex unwinding and DNA metabolic process. WB:WBGene00007525 C11G10.1 Predicted to be located in membrane. WB:WBGene00007528 C11H1.2 Predicted to enable voltage-gated monoatomic anion channel activity. Predicted to be involved in intracellular pH reduction. Predicted to be located in Golgi cisterna membrane. Is an ortholog of human GPR89A (G protein-coupled receptor 89A) and GPR89B (G protein-coupled receptor 89B). WB:WBGene00007529 mgrn-1 Predicted to enable ubiquitin protein ligase activity. Involved in negative regulation of vulval development and protein localization to basolateral plasma membrane. Located in cytoplasmic vesicle. Expressed in vulval precursor cell. Is an ortholog of human MGRN1 (mahogunin ring finger 1) and RNF157 (ring finger protein 157). WB:WBGene00007530 C11H1.5 Enriched in ABalapppaa; ABaraappaa; PVR; g2; and hyp3 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and nicotinic acid based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; Somatomedin-B and thrombospondin type-1 domain-containing protein; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00007531 C11H1.7 Predicted to enable signaling receptor binding activity. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 60. Is an ortholog of human CNPY4 (canopy FGF signaling regulator 4). WB:WBGene00007533 cbl-1 Predicted to enable carbon-sulfur lyase activity and pyridoxal phosphate binding activity. Predicted to be involved in transsulfuration. Predicted to be located in cytoplasm. WB:WBGene00007534 fubl-1 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA processing and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleus. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); liver cirrhosis; and malignant astrocytoma. Is an ortholog of human FUBP1 (far upstream element binding protein 1); FUBP3 (far upstream element binding protein 3); and KHSRP (KH-type splicing regulatory protein). WB:WBGene00007535 ttr-19 Predicted to be located in cell surface and extracellular region. WB:WBGene00007536 daf-36 Predicted to enable oxidoreductase activity. Predicted to be involved in cholesterol metabolic process. Located in cytoplasm. Expressed in head mesodermal cell; intestine; neurons; and seam cell. WB:WBGene00007537 fipr-8 Enriched in several structures, including AWC-OFF; MSaapaapa; MSpapaapa; anterior hypodermis; and pharyngeal cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Ethanol; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007538 C12D8.9 Enriched in ASER based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Cry5B; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00007539 B0334.12 Is affected by hda-6 and ptl-1 based on RNA-seq studies. WB:WBGene00007540 C12D8.13 Predicted to be located in membrane. WB:WBGene00007541 fipr-4 Enriched in AFD; ALN; arcade cell; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including manganese chloride; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00007542 pyt-1 Predicted to be located in membrane. WB:WBGene00007543 fipr-7 Enriched in XXX cell; arcade cell; ciliated neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including methylmercury hydroxide; manganese chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00007544 fipr-6 Enriched in AIYL; AIYR; arcade cell; and pm6 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including D-glucose; Zidovudine; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00007545 C13B4.1 Predicted to be located in membrane. WB:WBGene00007546 nhr-153 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in response to starvation and short-term memory. Predicted to be located in nucleus. Expressed in intestine; neurons; pharynx; and rectum. WB:WBGene00007547 nhr-154 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in response to starvation. Predicted to be located in nucleus. Expressed in alimentary muscle; head neurons; intestine; pharynx; and rectal valve cell. WB:WBGene00007548 C13C4.4 Predicted to enable inorganic diphosphate phosphatase activity and phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in cytosol. Is an ortholog of human LHPP (phospholysine phosphohistidine inorganic pyrophosphate phosphatase). WB:WBGene00007549 spin-1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in tail. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 115. Is an ortholog of human SPNS1 (SPNS lysolipid transporter 1, lysophospholipid); SPNS2 (SPNS lysolipid transporter 2, sphingosine-1-phosphate); and SPNS3 (SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)). WB:WBGene00007550 C13C4.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00007551 C13C4.7 Enriched in body wall muscle cell; coelomocyte; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and unc-30 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PLAT/LH2 domain superfamily and PLAT/LH2 domain. WB:WBGene00007552 dyf-4 Predicted to be located in extracellular region. WB:WBGene00007553 C13G3.1 Enriched in several structures, including accessory cell; germ line; nerve ring neurons; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including aldicarb; hydrogen sulfide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007554 pptr-2 Predicted to enable protein phosphatase activator activity. Involved in P granule assembly. Predicted to be located in cytosol and nucleus. Predicted to be part of protein phosphatase type 2A complex. Expressed in head and tail. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 35. Is an ortholog of human PPP2R5D (protein phosphatase 2 regulatory subunit B'delta). WB:WBGene00007555 dohh-1 Predicted to enable deoxyhypusine monooxygenase activity and iron ion binding activity. Predicted to be located in cytoplasm. Expressed in head. Is an ortholog of human DOHH (deoxyhypusine hydroxylase). WB:WBGene00007556 algn-9 Predicted to enable alpha-1,2-mannosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Il. Is an ortholog of human ALG9 (ALG9 alpha-1,2-mannosyltransferase). WB:WBGene00007557 C14A4.6 Predicted to be located in membrane. WB:WBGene00007558 C14A4.7 Predicted to be located in membrane. WB:WBGene00007559 C14A4.8 Predicted to enable FFAT motif binding activity. Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum-plasma membrane tethering. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. WB:WBGene00007560 C14A4.9 Enriched in germline precursor cell; hypodermis; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-six chemicals including methylmercury hydroxide; 1-methylnicotinamide; and methylmercuric chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00007561 ccm-3 Enables protein kinase binding activity. Involved in several processes, including endoplasmic reticulum organization; positive regulation of endocytic recycling; and regulation of Golgi organization. Located in cytoplasm; cytoplasmic side of apical plasma membrane; and growing cell tip. Expressed in several structures, including excretory canal; germ line; intestinal cell; oocyte; and pharynx. Used to study cerebral cavernous malformation. Human ortholog(s) of this gene implicated in cerebral cavernous malformation 3. Is an ortholog of human PDCD10 (programmed cell death 10). WB:WBGene00007562 C14A4.12 Predicted to be located in membrane. Expressed in excretory canal; pharyngeal-intestinal valve; virL; and virR. WB:WBGene00007563 C14A4.13 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00007564 mrps-22 Predicted to be a structural constituent of ribosome. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 5 and ovarian dysgenesis 7. Is an ortholog of human MRPS22 (mitochondrial ribosomal protein S22). WB:WBGene00007565 clec-48 Predicted to enable signaling receptor activity. Is an ortholog of human MRC1 (mannose receptor C-type 1). WB:WBGene00007567 C14A6.3 Predicted to be located in membrane. WB:WBGene00007568 C14A6.4 No description available WB:WBGene00007569 C14A6.5 Enriched in DA neuron; NSM; and VA neuron based on tiling array studies. Is affected by several genes including daf-2; age-1; and aak-2 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; glycine; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00007570 C14A6.6 Predicted to be located in membrane. WB:WBGene00007571 C14A6.7 Predicted to be located in membrane. WB:WBGene00007572 C14A6.8 Predicted to be located in membrane. WB:WBGene00007573 C14B1.2 Predicted to be located in membrane. WB:WBGene00007574 C14B1.3 Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; glycoprotein catabolic process; and ubiquitin-dependent ERAD pathway. Predicted to be located in cytoplasm. Predicted to be part of SCF ubiquitin ligase complex. Is an ortholog of human FBXO6 (F-box protein 6). WB:WBGene00007576 dph-1 Predicted to enable 4 iron, 4 sulfur cluster binding activity. Predicted to contribute to 2-(3-amino-3-carboxypropyl)histidine synthase activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine. Predicted to be located in protein-containing complex. Is an ortholog of human DPH1 (diphthamide biosynthesis 1). WB:WBGene00007577 nrde-1 Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in nucleus. WB:WBGene00007578 C14B1.7 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including rotenone; manganese chloride; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00007579 C14B1.8 Enriched in cephalic sheath cell; coelomocyte; germ line; intestine; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including skn-1; hsf-1; and aak-2 based on microarray and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; rotenone; and levamisole based on microarray and RNA-seq studies. Human SIKE1 enables protein kinase binding activity and small GTPase binding activity. Is predicted to encode a protein with the following domain: SIKE family. Is an ortholog of human FGFR1OP2 (FGFR1 oncogene partner 2) and SIKE1 (suppressor of IKBKE 1). WB:WBGene00007580 gldi-5 Enriched in several structures, including ABplapaaap; I5 neuron; XXX cell; cholinergic neurons; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; Zidovudine; and metformin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Chondroitin proteoglycan 4. WB:WBGene00007581 alkb-8 Predicted to enable tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity and tRNA binding activity. Predicted to be involved in tRNA methylation and tRNA wobble uridine modification. Located in cytoplasm. Expressed in several structures, including body wall musculature; egg-laying apparatus; intestinal cell; pharyngeal muscle cell; and somatic gonad. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 71. Is an ortholog of human ALKBH8 (alkB homolog 8, tRNA methyltransferase). WB:WBGene00007583 C14B4.2 Enriched in several structures, including enteric muscle; head mesodermal cell; neurons; rectal epithelial cell; and rectal muscle based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and let-60 based on RNA-seq and microarray studies. Is affected by twelve chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00007584 C14C10.1 Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human SLC25A3 (solute carrier family 25 member 3). WB:WBGene00007585 C14C10.2 Enriched in several structures, including ABaraapapp; AFD; MSpppaaa; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; Zidovudine; and metformin based on RNA-seq studies. WB:WBGene00007586 ril-2 Predicted to be involved in lysosome organization and regulation of intracellular pH. Predicted to be located in lysosome. WB:WBGene00007587 mma-1 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in regulation of mitochondrial translation. Predicted to be located in mitochondrion and nucleus. WB:WBGene00007588 C14C10.5 Predicted to enable lysine-acetylated histone binding activity; peptidase activator activity; and proteasome binding activity. Predicted to be involved in proteasomal ubiquitin-independent protein catabolic process. Predicted to be located in cytosol and nucleus. Is an ortholog of human PSME4 (proteasome activator subunit 4). WB:WBGene00007589 erg-28 Predicted to be located in dendrite and endoplasmic reticulum membrane. Expressed in body wall musculature and intestine. WB:WBGene00007590 ttr-43 Predicted to be located in cell surface and extracellular region. WB:WBGene00007591 zipt-13 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome spondylodysplastic type 3. Is an ortholog of human SLC39A13 (solute carrier family 39 member 13). WB:WBGene00007592 C14H10.2 Enriched in several structures, including accessory cell; head mesodermal cell; hypodermis; muscle cell; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and lin-4 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; methylmercury hydroxide; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. Is an ortholog of human JAKMIP3 (Janus kinase and microtubule interacting protein 3). WB:WBGene00007593 C14H10.3 Predicted to enable transferase activity. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human PDXDC1 (pyridoxal dependent decarboxylase domain containing 1). WB:WBGene00007594 lgc-23 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00007595 tmem-145 Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be located in membrane. Is an ortholog of human TMEM145 (transmembrane protein 145). WB:WBGene00007597 C15A11.2 Enriched in GABAergic neurons; body wall muscle cell; germ line; and muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00007598 C15A11.4 Predicted to be located in membrane. WB:WBGene00007599 C15A11.7 Predicted to be located in membrane. WB:WBGene00007600 C15C6.1 Predicted to be located in membrane. WB:WBGene00007601 C15C6.2 Enriched in amphid sheath cell; germ line; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by thirty chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00007602 C15C6.3 Enriched in AFD; AVK; MSpaaapa; NSM; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and lin-35 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including silicon dioxide nanoparticle; paraquat; and Atrazine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007603 popl-4 Predicted to enable ribonuclease P RNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in cytoplasm. Predicted to be part of ribonuclease MRP complex and ribonuclease P complex. Is an ortholog of human POP4 (POP4 homolog, ribonuclease P/MRP subunit). WB:WBGene00007604 xbx-9 Predicted to be located in membrane. Expressed in neurons. WB:WBGene00007605 hrg-7 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Expressed in amphid neurons and phasmid neurons. WB:WBGene00007606 C15C8.4 Predicted to enable heparin binding activity; low-density lipoprotein particle receptor binding activity; and receptor antagonist activity. Predicted to be involved in regulation of receptor-mediated endocytosis. Predicted to be located in endomembrane system. Expressed in head neurons; intestine; nerve ring neurons; and tail neurons. Human ortholog(s) of this gene implicated in Alzheimer's disease; dementia; myocardial infarction; and myopia. Is an ortholog of human LRPAP1 (LDL receptor related protein associated protein 1). WB:WBGene00007607 C15C8.5 Predicted to be located in membrane. WB:WBGene00007608 C15C8.6 Predicted to be located in membrane. WB:WBGene00007609 C15C8.7 Enriched in several structures, including body wall muscle cell; distal tip cell; germ line; neurons; and retrovesicular ganglion based on Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including elt-2; fbf-1; and sma-2 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; multi-walled carbon nanotube; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00007610 C15H7.3 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00007611 C15H7.4 Enriched in somatic gonad precursor and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PH domain and PH_15 domain. WB:WBGene00007613 C15H11.1 Predicted to be located in cytoskeleton. WB:WBGene00007614 gnrr-2 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00007615 set-31 Predicted to be located in chromosome, centromeric region. Expressed in hypodermis. WB:WBGene00007616 rpoa-12 Predicted to enable DNA-directed 5'-3' RNA polymerase activity; nucleic acid binding activity; and zinc ion binding activity. Predicted to contribute to RNA polymerase I activity. Predicted to be involved in termination of RNA polymerase I transcription. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I complex. Is an ortholog of human POLR1H (RNA polymerase I subunit H). WB:WBGene00007617 rrbs-1 Predicted to be involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and ribosomal large subunit assembly. Predicted to be located in nucleolus. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human RRS1 (ribosome biogenesis regulator 1 homolog). WB:WBGene00007618 C15H11.10 Predicted to be located in membrane. WB:WBGene00007619 C15H11.11 Predicted to be located in membrane. WB:WBGene00007620 ocrl-1 Predicted to enable phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation and positive regulation of flagellated sperm motility. Predicted to be located in several cellular components, including neuronal cell body; nucleus; and plasma membrane bounded cell projection. Human ortholog(s) of this gene implicated in Dent disease and oculocerebrorenal syndrome. Is an ortholog of human INPP5B (inositol polyphosphate-5-phosphatase B). WB:WBGene00007621 C16C2.4 Predicted to be involved in TORC2 signaling and regulation of short-term neuronal synaptic plasticity. Predicted to be located in Golgi apparatus; nucleus; and synapse. Is an ortholog of human SYAP1 (synapse associated protein 1). WB:WBGene00007622 C16C10.1 Predicted to be involved in mitochondrial transmembrane transport. Predicted to be located in mitochondrion. Expressed in tail. Is an ortholog of human SLC25A40 (solute carrier family 25 member 40). WB:WBGene00007623 C16C10.2 Predicted to be involved in translation. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human UTP11 (UTP11 small subunit processome component). WB:WBGene00007624 hrde-1 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Involved in germ cell development and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in nucleus. Part of RNAi effector complex. Expressed in germ cell and germ line. WB:WBGene00007625 C16C10.4 Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of human SAP18 (Sin3A associated protein 18). WB:WBGene00007626 rnf-121 Enables ubiquitin protein ligase activity. Involved in PERK-mediated unfolded protein response; inductive cell migration; and ubiquitin-dependent ERAD pathway. Located in Golgi membrane and sarcoplasmic reticulum membrane. Expressed in body wall musculature; gonad; hypodermis; and vulva. Is an ortholog of human RNF121 (ring finger protein 121) and RNF175 (ring finger protein 175). WB:WBGene00007627 ccdc-55 Predicted to enable mRNA binding activity. Involved in inductive cell migration and nematode larval development. Located in cytoplasm and nucleus. Expressed in gonad; hypodermis; muscle cell; and vulva. Is an ortholog of human NSRP1 (nuclear speckle splicing regulatory protein 1). WB:WBGene00007628 C16C10.8 Predicted to enable DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and rRNA processing. Predicted to be located in nucleolus. Is an ortholog of human LYAR (Ly1 antibody reactive). WB:WBGene00007629 C16C10.9 Enriched in several structures, including ABalppppapa; XXX cell; amphid neurons; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and csr-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00007630 har-1 Involved in mitochondrion organization. Acts upstream of with a positive effect on determination of adult lifespan. Located in mitochondrion and striated muscle dense body. Expressed in intestine and ventral nerve cord. Human ortholog(s) of this gene implicated in isolated mitochondrial myopathy and neurodegenerative disease (multiple). Is an ortholog of human CHCHD10 (coiled-coil-helix-coiled-coil-helix domain containing 10). WB:WBGene00007631 wht-3 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including gout; hematologic cancer (multiple); and toxic encephalopathy. Is an ortholog of human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)). WB:WBGene00007632 C16C10.13 Enriched in several structures, including ABplpaaaap; ABprpaaaap; germ line; neurons; and rect_D based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including mianserin; multi-walled carbon nanotube; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00007633 C16D2.1 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. WB:WBGene00007635 npr-4 Predicted to enable G protein-coupled receptor activity. Involved in regulation of muscle contraction. Predicted to be located in membrane. Expressed in several structures, including PQR; coelomocyte; interneuron; nerve ring; and rectal gland cell. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in hypertension. Is an ortholog of human PRLHR (prolactin releasing hormone receptor). WB:WBGene00007637 dhhc-7 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. WB:WBGene00007638 C17D12.3 Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Predicted to be involved in glycoprotein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Predicted to be located in cytosol and nucleus. WB:WBGene00007639 C17D12.5 Enriched in amphid sheath cell; germ line; neurons; retrovesicular ganglion; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Ubiquitin-conjugating enzyme/RWD-like. WB:WBGene00007640 pcmd-1 Expressed in germ line. WB:WBGene00007641 C17E4.1 Enriched in several structures, including ADE; amphid sheath cell; germ line; lateral ganglion; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00007642 C17E4.2 Predicted to be located in motile cilium. Expressed in head; intestine; and vulval muscle. WB:WBGene00007643 marc-3 Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in membrane. Expressed in accessory cell and pharyngeal muscle cell. Is an ortholog of human MARCHF3 (membrane associated ring-CH-type finger 3). WB:WBGene00007644 mjl-1 Predicted to be located in membrane. WB:WBGene00007645 C17E4.6 Predicted to enable ATP-dependent H2AZ histone chaperone activity. Predicted to be involved in chromatin remodeling and regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of human VPS72 (vacuolar protein sorting 72 homolog). WB:WBGene00007646 nkb-1 Predicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Expressed in neurons and non-striated muscle. Human ortholog(s) of this gene implicated in several diseases, including atrophic gastritis; autoimmune gastritis; and essential hypertension. Is an ortholog of several human genes including ATP1B1 (ATPase Na+/K+ transporting subunit beta 1); ATP1B2 (ATPase Na+/K+ transporting subunit beta 2); and ATP1B3 (ATPase Na+/K+ transporting subunit beta 3). WB:WBGene00007647 C17E4.10 Enriched in several structures, including ABalpapaap; germ line; interfacial epithelial cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including dpy-10; daf-12; and gld-1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including D-glucose; levamisole; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007648 folr-1 Predicted to be located in membrane. WB:WBGene00007649 C17G1.2 Predicted to be located in membrane. WB:WBGene00007650 ugt-23 Predicted to enable UDP-glycosyltransferase activity. Involved in gastrulation. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00007651 nra-3 Predicted to enable metal ion binding activity. Predicted to be located in nucleus. WB:WBGene00007652 C17G1.5 Enriched in several structures, including CAN; anterior hypodermis; excretory system; interfacial epithelial cell; and rectal gland cell based on Chronogram; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including 1-methylnicotinamide; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00007653 cysl-1 Enables cysteine synthase activity and enzyme binding activity. Involved in cysteine biosynthetic process from serine and response to hypoxia. Located in striated muscle dense body. Expressed in body wall musculature; head ganglion; hypodermis; neurons; and non-striated muscle. WB:WBGene00007654 C17H1.1 Is affected by several genes including skn-1; eat-2; and hpl-2 based on RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00007655 C17H1.2 Enriched in cephalic sheath cell; dopaminergic neurons; germ line; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00007656 pals-2 Expressed in hypodermis and neurons. WB:WBGene00007657 pals-3 Enriched in excretory cell and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; Mercuric Chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00007658 pals-4 Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007659 pals-5 Involved in innate immune response. WB:WBGene00007660 pals-6 Enriched in OLL; PVD; dopaminergic neurons; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-three chemicals including Nitric Oxide; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00007661 pals-7 Is affected by several genes including skn-1; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Mercuric Chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00007662 pals-8 Enriched in AIZ; AVG; dopaminergic neurons; and mechanosensory neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including Mercuric Chloride; Zidovudine; and allantoin based on microarray and RNA-seq studies. WB:WBGene00007664 seb-3 Predicted to enable G protein-coupled peptide receptor activity. Involved in behavioral response to ethanol; locomotory behavior; and response to heat. Located in axon and neuronal cell body. Expressed in body wall musculature; nervous system; ray 1; and rectal gland cell. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including achalasia; inflammatory bowel disease (multiple); and type 2 diabetes mellitus. Is an ortholog of several human genes including ADCYAP1R1 (ADCYAP receptor type I); GHRHR (growth hormone releasing hormone receptor); and GIPR (gastric inhibitory polypeptide receptor). WB:WBGene00007666 C18B12.4 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 73. Is an ortholog of human RNF13 (ring finger protein 13); RNF167 (ring finger protein 167); and ZNRF4 (zinc and ring finger 4). WB:WBGene00007667 fbxa-97 Enriched in body wall muscle cell; hypodermis; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including stavudine; metformin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00007668 ergi-2 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum; and membrane. Expressed in anal depressor muscle; anal sphincter muscle; anterior distal tip cell; posterior distal tip cell; and tail neurons. Is an ortholog of human ERGIC2 (ERGIC and golgi 2). WB:WBGene00007669 C18D1.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00007670 stg-1 Enables channel regulator activity. Involved in positive regulation of glutamatergic synaptic transmission. Predicted to be located in postsynaptic density membrane. Predicted to be part of AMPA glutamate receptor complex. Expressed in neurons. Human ortholog(s) of this gene implicated in several diseases, including acute myocardial infarction; autosomal dominant intellectual developmental disorder 10; and childhood absence epilepsy. Is an ortholog of several human genes including CACNG2 (calcium voltage-gated channel auxiliary subunit gamma 2); CACNG3 (calcium voltage-gated channel auxiliary subunit gamma 3); and CACNG5 (calcium voltage-gated channel auxiliary subunit gamma 5). WB:WBGene00007672 fbxa-136 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including Mercuric Chloride; Tunicamycin; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box A protein FB224; Ubiquitin interacting motif; and Phosphorylation site. WB:WBGene00007673 C18D4.3 Is affected by several genes including daf-12; set-2; and smn-1 based on RNA-seq studies. Is affected by aldicarb and resveratrol based on microarray studies. WB:WBGene00007674 C18D4.4 Enriched in cephalic sheath cell; excretory cell; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Vitelline membrane outer layer protein I (VOMI) and Vitelline membrane outer layer protein I (VOMI) superfamily. WB:WBGene00007675 C18D4.6 Enriched in several structures, including ABplpppaaa; ABplppppaa; ABprppppaa; neurons; and rectal epithelial cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on microarray and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; Rifampin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00007676 srz-57 Is affected by let-60; daf-2; and daf-16 based on microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies. WB:WBGene00007677 C18D4.8 Enriched in OLL; PVD; and intestine based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; D-glucose; and levamisole based on RNA-seq and microarray studies. WB:WBGene00007678 srz-90 Predicted to be located in membrane. WB:WBGene00007679 C18D11.1 Predicted to be located in membrane. WB:WBGene00007680 maa-1 Enables fatty-acyl-CoA binding activity. Involved in endocytic recycling; endosome organization; and multicellular organism reproduction. Located in apical part of cell; basal part of cell; and bounding membrane of organelle. Expressed in hypodermis. Is an ortholog of human ACBD4 (acyl-CoA binding domain containing 4). WB:WBGene00007681 C18D11.3 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-12; let-7; and gld-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by seven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF4602) and Protein of unknown function DUF4602. WB:WBGene00007682 C18D11.6 Predicted to be involved in innate immune response. WB:WBGene00007683 C18E9.2 Predicted to be involved in post-translational protein targeting to membrane, translocation. Predicted to be located in endoplasmic reticulum and membrane. Is an ortholog of human SEC62 (SEC62 homolog, preprotein translocation factor). WB:WBGene00007684 ndub-3 Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease and nuclear type mitochondrial complex I deficiency 25. Is an ortholog of human NDUFB3 (NADH:ubiquinone oxidoreductase subunit B3). WB:WBGene00007685 C18E9.5 Predicted to be located in membrane. WB:WBGene00007686 tomm-40 Predicted to enable protein transmembrane transporter activity. Involved in protein import into mitochondrial matrix. Located in mitochondrial membrane. Expressed in gonadal sheath cell; intestine; pharyngeal muscle cell; and tail hypodermis. Human ortholog(s) of this gene implicated in cerebral infarction. Is an ortholog of human TOMM40 (translocase of outer mitochondrial membrane 40) and TOMM40L (translocase of outer mitochondrial membrane 40 like). WB:WBGene00007687 C18E9.7 Enriched in arcade cell; excretory gland cell; pharyngeal muscle cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; D-glucose; and stavudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome and vesicoureteral reflux. Human TNXB enables collagen fibril binding activity. Is predicted to encode a protein with the following domains: TM proximal of protein tyrosine phosphatase, receptor type J; Fibronectin type III superfamily; Immunoglobulin-like fold; PTPRJ, transmembrane domain; Fibronectin type III; and Fibronectin type III domain. Is an ortholog of human TNXA (tenascin XA (pseudogene)) and TNXB (tenascin XB). WB:WBGene00007688 C18E9.8 Enriched in AVEL; AVER; amphid sheath cell; germ line; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00007689 C18E9.9 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00007690 sftd-3 Predicted to be involved in protein transport and vesicle-mediated transport. Predicted to be located in membrane. Is an ortholog of human SFT2D3 (SFT2 domain containing 3). WB:WBGene00007691 cest-8 Predicted to enable carboxylic ester hydrolase activity. Involved in ascaroside biosynthetic process. Predicted to be located in membrane. WB:WBGene00007692 cest-9.1 Predicted to be located in membrane. WB:WBGene00007693 cest-7 Predicted to enable carboxylic ester hydrolase activity. Predicted to be located in membrane. WB:WBGene00007694 C23H4.6 Predicted to enable damaged DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination. Predicted to be located in nucleus and site of double-strand break. Predicted to be part of Smc5-Smc6 complex. Expressed in tail. Is an ortholog of human SMC6 (structural maintenance of chromosomes 6). WB:WBGene00007695 cest-9.2 Predicted to enable carboxylic ester hydrolase activity. Involved in ascaroside biosynthetic process. Predicted to be located in membrane. WB:WBGene00007696 tram-1 Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation and protein insertion into ER membrane. Located in dendrite terminus; periciliary membrane compartment; and rough endoplasmic reticulum. Is an ortholog of human TRAM1 (translocation associated membrane protein 1); TRAM1L1 (translocation associated membrane protein 1 like 1); and TRAM2 (translocation associated membrane protein 2). WB:WBGene00007697 C24F3.2 Predicted to enable protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in nucleus. Is an ortholog of human DUSP12 (dual specificity phosphatase 12). WB:WBGene00007698 qns-1 Enables NAD+ synthase activity. Involved in NAD biosynthetic process and determination of adult lifespan. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in high grade glioma. Is an ortholog of human NADSYN1 (NAD synthetase 1). WB:WBGene00007699 C24H11.1 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00007700 C24H11.2 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00007701 srd-74 Predicted to be located in membrane. WB:WBGene00007702 C24H11.5 Predicted to be involved in spliceosomal snRNP assembly. Predicted to be part of Sm-like protein family complex. Is an ortholog of human GEMIN7 (gem nuclear organelle associated protein 7). WB:WBGene00007703 gbf-1 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in endosomal transport; organelle organization; and secretion. Located in Golgi cis cisterna and endoplasmic reticulum exit site. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate A. Is an ortholog of human GBF1 (golgi brefeldin A resistant guanine nucleotide exchange factor 1). WB:WBGene00007704 mdt-21 Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Is an ortholog of human MED21 (mediator complex subunit 21). WB:WBGene00007705 C25A1.1 Predicted to be located in nucleus. Is an ortholog of human PSME3IP1 (proteasome activator subunit 3 interacting protein 1). WB:WBGene00007707 fath-1 Predicted to enable fatty acid alpha-hydroxylase activity. Predicted to be involved in fatty acid metabolic process. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 35. Is an ortholog of human FA2H (fatty acid 2-hydroxylase). WB:WBGene00007708 nola-3 Predicted to enable telomerase RNA binding activity. Predicted to be involved in rRNA pseudouridine synthesis and snRNA pseudouridine synthesis. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 1. Is an ortholog of human NOP10 (NOP10 ribonucleoprotein). WB:WBGene00007709 clec-87 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Is an ortholog of human CLEC2L (C-type lectin domain family 2 member L); KLRB1 (killer cell lectin like receptor B1); and KLRG1 (killer cell lectin like receptor G1). WB:WBGene00007710 rsa-1 Enables protein phosphatase 2A binding activity. Involved in embryo development; mitotic spindle assembly; and protein localization to organelle. Located in centrosome. Human ortholog(s) of this gene implicated in spermatogenic failure 36. Is an ortholog of human PPP2R3C (protein phosphatase 2 regulatory subunit B''gamma). WB:WBGene00007711 lid-1 Predicted to enable carboxylic ester hydrolase activity and lysophosphatidic acid acyltransferase activity. Predicted to be involved in lipid homeostasis and phosphatidic acid biosynthetic process. Located in lipid droplet. Expressed in intestinal cell. Used to study Chanarin-Dorfman syndrome. Human ortholog(s) of this gene implicated in Chanarin-Dorfman syndrome; autosomal recessive congenital ichthyosis 1; and colon adenocarcinoma. Is an ortholog of human ABHD4 (abhydrolase domain containing 4, N-acyl phospholipase B) and ABHD5 (abhydrolase domain containing 5, lysophosphatidic acid acyltransferase). WB:WBGene00007712 mrpl-34 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL43 (mitochondrial ribosomal protein L43). WB:WBGene00007713 C25A1.15 Enriched in seam cell based on RNA-seq studies. Is affected by several genes including daf-12; mut-2; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine and cadmium based on microarray studies. WB:WBGene00007714 melo-3 Predicted to be located in cytoskeleton. WB:WBGene00007715 C25D7.2 Enriched in germ line and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00007716 fbxa-82 Enriched in intestine and muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including multi-walled carbon nanotube; levamisole; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00007717 C25D7.5 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00007718 otub-1 Enables cysteine-type deubiquitinase activity. Predicted to be involved in proteolysis. Located in plasma membrane. Expressed in distal tip cell; neuronal sheath cell; neurons; pharynx; and ventral nerve cord. Human ortholog(s) of this gene implicated in IgA glomerulonephritis and lupus nephritis. Is an ortholog of human OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1). WB:WBGene00007719 C25D7.9 Is affected by several genes including eat-2; smg-2; and spn-4 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00007720 C25D7.10 Predicted to be located in membrane. WB:WBGene00007721 C25D7.12 Enriched in germ line; neurons; retrovesicular ganglion; and somatic gonad precursor based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007722 C25D7.15 Predicted to be located in membrane. WB:WBGene00007723 C25F9.2 Predicted to enable DNA binding activity; DNA-directed DNA polymerase activity; and nucleotide binding activity. Predicted to be involved in DNA biosynthetic process and DNA replication. Predicted to be part of DNA polymerase complex. WB:WBGene00007724 C25F9.4 Predicted to enable ATP binding activity and ATP-dependent chromatin remodeler activity. Predicted to be involved in chromatin remodeling. WB:WBGene00007725 C25F9.5 Predicted to enable ATP binding activity and ATP-dependent chromatin remodeler activity. Predicted to be involved in chromatin remodeling. WB:WBGene00007726 C25F9.6 Enriched in DVC; head mesodermal cell; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Rifampin; D-glucose; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00007727 C25F9.8 Enriched in male based on RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00007728 C25F9.9 Enriched in intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including tryptophan; Rifampin; and Sirolimus based on microarray; RNA-seq; and proteomic studies. WB:WBGene00007729 clec-185 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00007730 C25G4.2 Predicted to enable hydrolase activity. Predicted to be involved in response to retinoic acid. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in ovarian cancer. Is an ortholog of human OVCA2 (OVCA2 serine hydrolase domain containing). WB:WBGene00007731 C25G4.3 Predicted to be involved in rRNA processing. Is an ortholog of human RBFA (ribosome binding factor A). WB:WBGene00007732 spe-44 Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in positive regulation of transcription by RNA polymerase II and spermatogenesis. Located in autosome. Expressed in germ line; sperm; and in male. Is an ortholog of human GMEB1 (glucocorticoid modulatory element binding protein 1) and GMEB2 (glucocorticoid modulatory element binding protein 2). WB:WBGene00007733 smz-1 Involved in male meiosis chromosome segregation. Part of chromatin. Expressed in male gonad and sperm. WB:WBGene00007734 C25G4.7 Enriched in several structures, including ABplppppap; ABprppppap; AVL; germ line; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; pie-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercury hydroxide; Tunicamycin; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00007735 C25G4.8 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including skn-1; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1265; SKP1/BTB/POZ domain superfamily; and Protein of unknown function (DUF1265). WB:WBGene00007736 igdb-2 Predicted to be located in plasma membrane. Expressed in amphid sheath cell; amphid socket cell; and hypodermis. WB:WBGene00007739 C26C6.4 Predicted to enable transferase activity. Predicted to be located in membrane. WB:WBGene00007740 C26C6.6 Predicted to enable metal ion binding activity. WB:WBGene00007741 glb-8 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in body wall musculature. WB:WBGene00007742 C26C6.8 Enriched in AFD and NSM based on RNA-seq studies. Is affected by several genes including daf-12; sek-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Variant SH3 domain; SH3 domain; and SH3-like domain superfamily. WB:WBGene00007743 C26C6.9 Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in intracellular membrane-bounded organelle. WB:WBGene00007744 C26D10.3 Predicted to enable flavin adenine dinucleotide binding activity and oxidoreductase activity. Human ortholog(s) of this gene implicated in myofibrillar myopathy 8. Is an ortholog of human PYROXD1 (pyridine nucleotide-disulphide oxidoreductase domain 1). WB:WBGene00007745 C26D10.4 Predicted to enable fucokinase activity. Predicted to be involved in GDP-L-fucose salvage. Is an ortholog of human FCSK (fucose kinase). WB:WBGene00007746 C26D10.6 Enriched in intestine; neurons; pharyngeal-intestinal valve; and retrovesicular ganglion based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; rrf-3; and hsf-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007747 C26E1.1 Enriched in ABalppppapa; ABpraaapapa; Caapa; RIH; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by rsr-2 and etr-1 based on tiling array and RNA-seq studies. WB:WBGene00007748 C26E1.2 Predicted to enable DNA binding activity. WB:WBGene00007749 ceh-79 Predicted to enable DNA binding activity. Expressed in several structures, including amphid neurons; body wall musculature; gonad; pharyngeal neurons; and tail neurons. WB:WBGene00007750 syg-2 Enables cell adhesion molecule binding activity and protein homodimerization activity. Involved in cell-cell signaling; nervous system development; and protein localization to synapse. Predicted to be located in cell-cell junction and plasma membrane. Expressed in several structures, including P6.paa; P6.pap; P6.ppa; egg-laying apparatus; and neurons. Used to study nephrotic syndrome. Human ortholog(s) of this gene implicated in nephrotic syndrome type 1. Is an ortholog of human NPHS1 (NPHS1 adhesion molecule, nephrin). WB:WBGene00007751 C26G2.2 Predicted to be located in membrane. WB:WBGene00007752 wdfy-3 Predicted to enable protein kinase binding activity. Predicted to be involved in protein localization. Predicted to be located in cytosol and membrane. Human ortholog(s) of this gene implicated in primary autosomal dominant microcephaly 18. Is an ortholog of human WDFY3 (WD repeat and FYVE domain containing 3). WB:WBGene00007753 enpp-1 Predicted to enable hydrolase activity. Predicted to be located in I band and striated muscle dense body. Expressed in ciliated neurons; pharynx; and vas deferens cuboidal cell. Human ortholog(s) of this gene implicated in several diseases, including arterial calcification of infancy; end stage renal disease; and ossification of the posterior longitudinal ligament of spine. Is an ortholog of human ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1); ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2); and ENPP3 (ectonucleotide pyrophosphatase/phosphodiesterase 3). WB:WBGene00007754 C27A7.2 Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Ethanol; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00007755 C27A7.3 Predicted to enable hydrolase activity and metal ion binding activity. Predicted to be located in I band and striated muscle dense body. Human ortholog(s) of this gene implicated in several diseases, including arterial calcification of infancy; end stage renal disease; and ossification of the posterior longitudinal ligament of spine. Is an ortholog of human ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1); ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2); and ENPP3 (ectonucleotide pyrophosphatase/phosphodiesterase 3). WB:WBGene00007756 C27A7.5 Predicted to enable asparaginase activity. Predicted to be involved in aspartate family amino acid metabolic process. Is an ortholog of human ASPG (asparaginase). WB:WBGene00007757 C27A7.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00007758 C27A7.8 Enriched in amphid sensillum; amphid sheath cell; excretory cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; Thrombospondin type 1 domain; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00007759 C27A7.9 Enriched in AVK based on RNA-seq studies. Is affected by several genes including clk-1; hpl-2; and mir-34 based on tiling array and microarray studies. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; Thrombospondin type 1 domain; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00007760 C27B7.2 Enriched in several structures, including ABplaapapa; ABpraapapa; body wall muscle cell; germ line; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twelve chemicals including mianserin; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF2358 and Uncharacterized conserved protein (DUF2358). Is an ortholog of human C6orf136 (chromosome 6 open reading frame 136). WB:WBGene00007761 rad-54.L2 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and SUMO binding activity. Involved in negative regulation of vulval development. Predicted to be located in nucleus. Predicted to be part of NuRD complex. Is an ortholog of human RAD54L2 (RAD54 like 2). WB:WBGene00007762 C27B7.5 Predicted to enable mRNA binding activity; single-stranded RNA binding activity; and translation regulator activity. Predicted to be involved in positive regulation of cytoplasmic translation. Predicted to be located in cytoplasm. WB:WBGene00007763 C27B7.6 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00007764 C27B7.7 Predicted to be located in extracellular region. WB:WBGene00007765 C27B7.9 Enriched in several structures, including body wall muscle cell from MS lineage; dopaminergic neurons; excretory cell; germ line; and head ganglion based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; tiling array; proteomic; and microarray studies. Is affected by nineteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00007766 C27C7.1 Enriched in several structures, including I5 neuron; XXX cell; cholinergic neurons; germ line; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007767 C27C7.2 Is affected by ubc-9; sir-2.1; and mrps-5 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00007768 C27C7.5 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00007769 C27C7.7 Predicted to enable transferase activity. WB:WBGene00007770 nhr-259 Predicted to be located in nucleus. WB:WBGene00007771 C27C12.1 Enriched in AFD; ASER; germ line; head mesodermal cell; and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by ten chemicals including D-glucose; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Armadillo-like helical. WB:WBGene00007772 egrh-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of oocyte maturation and negative regulation of ovulation. Located in nucleus and perinuclear region of cytoplasm. Expressed in body wall musculature; hermaphrodite somatic gonadal cell; nervous system; pharynx; and sperm. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); lung disease (multiple); and neuropathy (multiple). Is an ortholog of human EGR1 (early growth response 1) and EGR3 (early growth response 3). WB:WBGene00007773 C27C12.3 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Expressed in germ line. WB:WBGene00007774 C27C12.4 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00007775 acd-3 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Expressed in intestinal cell. WB:WBGene00007776 dmd-4 Enables ubiquitin binding activity. Involved in synapse pruning. Predicted to be located in nucleus. Expressed in neurons. Is an ortholog of human DMRT3 (doublesex and mab-3 related transcription factor 3). WB:WBGene00007777 C27D8.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00007778 C27D8.2 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by twenty-three chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/Kelch-associated and BTB And C-terminal Kelch. WB:WBGene00007779 C27D8.3 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription and signal transduction. WB:WBGene00007780 C27D8.4 Predicted to be located in membrane. Expressed in intestine and pharynx. WB:WBGene00007781 C27H2.1 No description available WB:WBGene00007784 ruvb-1 Predicted to enable DNA helicase activity. Involved in several processes, including TOR signaling; box C/D snoRNP assembly; and positive regulation of translation. Located in cytoplasm and nucleus. Expressed in gonad and pharyngeal cell. Is an ortholog of human RUVBL1 (RuvB like AAA ATPase 1). WB:WBGene00007785 tofu-1 Located in cytoplasm. WB:WBGene00007786 rmd-2 Predicted to enable microtubule binding activity. Predicted to be located in mitochondrion; mitotic spindle pole; and spindle microtubule. Is an ortholog of human RMDN2 (regulator of microtubule dynamics 2). WB:WBGene00007787 C27H6.8 Predicted to be located in cytoplasm and nucleus. Is an ortholog of human MYG1 (MYG1 exonuclease). WB:WBGene00007788 C28A5.1 Enriched in several structures, including body wall muscle cell from C lineage; germ line; head mesodermal cell; intestinal muscle; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00007789 C28A5.2 Enriched in germ line and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00007791 C28A5.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including endocytosis; positive regulation of canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. WB:WBGene00007792 C28D4.4 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on proteomic; microarray; RNA-seq; and tiling array studies. Is affected by twenty-one chemicals including Ethanol; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; Domain of unknown function DUF1248; and Protein of unknown function (DUF1248). WB:WBGene00007793 C28D4.5 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-five chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; Domain of unknown function DUF1248; and Protein of unknown function (DUF1248). WB:WBGene00007794 C28D4.7 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-five chemicals including Ethanol; methylmercuric chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF1248 and Protein of unknown function (DUF1248). WB:WBGene00007795 C28D4.8 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by fifteen chemicals including methylmercuric chloride; D-glucose; and Doxycycline based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; Domain of unknown function DUF1248; and Protein of unknown function (DUF1248). WB:WBGene00007796 C28D4.10 Enriched in GABAergic neurons; body wall muscle cell; germ line; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including csr-1; hpl-2; and mir-34 based on RNA-seq and microarray studies. Is affected by six chemicals including methylmercuric chloride; mianserin; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Ubiquitin-like domain superfamily. WB:WBGene00007797 C29A12.1 Enriched in ABplapappp; ABprapappp; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00007798 C29A12.2 Is affected by several genes including daf-2; hsf-1; and sek-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Zidovudine; Sodium Chloride; and cholesterol based on RNA-seq studies. WB:WBGene00007799 nrx-1 Involved in negative regulation of receptor clustering. Located in presynaptic active zone. Expressed in GABAergic neurons; cholinergic neurons; nervous system; and ventral cord neurons. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in Pitt-Hopkins-like syndrome 2. Is an ortholog of human NRXN1 (neurexin 1) and NRXN3 (neurexin 3). WB:WBGene00007800 C29A12.6 Enriched in hypodermis; intestine; neurons; seam cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and let-7 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: von Willebrand factor A-like domain superfamily; von Willebrand factor, type A; and von Willebrand factor type A domain. WB:WBGene00007801 trpa-1 Predicted to enable monoatomic ion channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Located in neuronal cell body and non-motile cilium. Expressed in several structures, including excretory system; pharyngeal muscle cell; sensory neurons; ventral nerve cord; and vulva. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 1. Is an ortholog of human TRPA1 (transient receptor potential cation channel subfamily A member 1). WB:WBGene00007802 cutl-27 Predicted to be located in membrane. WB:WBGene00007803 C29E6.6 No description available WB:WBGene00007804 C29F3.3 Enriched in excretory cell and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including Ethanol; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00007805 clec-231 Enriched in arcade cell based on single-cell RNA-seq studies. Is affected by several genes including clk-1; mdt-15; and dpy-21 based on microarray; tiling array; and RNA-seq studies. Is affected by multi-walled carbon nanotube and Colistin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00007806 clec-230 Enriched in germline precursor cell; hypodermis; pharyngeal muscle cell; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including tryptophan; D-glucose; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00007807 C29F3.7 Involved in innate immune response. Located in membrane raft. WB:WBGene00007808 best-7 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). WB:WBGene00007809 C29F4.3 Predicted to be located in membrane. WB:WBGene00007810 C29F7.1 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00007811 C29F7.2 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Expressed in pharynx. WB:WBGene00007812 C29F7.3 Enables UMP kinase activity. Involved in UDP biosynthetic process. Predicted to be located in cytoplasm and nucleus. Expressed in pharynx. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human CMPK1 (cytidine/uridine monophosphate kinase 1). WB:WBGene00007813 jmjd-3.3 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; chromatin DNA binding activity; and histone H3K27me2/H3K27me3 demethylase activity. Predicted to be involved in regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of MLL3/4 complex. WB:WBGene00007816 C30F2.2 Predicted to enable metal ion binding activity. WB:WBGene00007817 idpp-14 Enriched in excretory gland cell; pharynx; and pm6 based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by fourteen chemicals including Tunicamycin; D-glucose; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00007818 C30F2.4 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00007819 C30F2.5 Predicted to be located in membrane. WB:WBGene00007820 clec-199 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Expressed in head neurons and in male. WB:WBGene00007821 clec-201 Is affected by several genes including smg-2; ahr-1; and etr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00007822 clec-202 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. WB:WBGene00007823 C30H6.5 Enriched in AFD; hypodermis; and interfacial epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-two chemicals including tryptophan; 1-methylnicotinamide; and nicotinic acid based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00007824 dlat-2 Predicted to enable dihydrolipoyllysine-residue acetyltransferase activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Predicted to be part of mitochondrial pyruvate dehydrogenase complex. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency and sarcoma. Is an ortholog of human PDHX (pyruvate dehydrogenase complex component X). WB:WBGene00007825 C30H6.8 Enriched in NSM; germ line; germline precursor cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including hsf-1; let-7; and gld-1 based on microarray; proteomic; and RNA-seq studies. Is affected by five chemicals including rotenone; antimycin; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Thioredoxin-like superfamily; and Thioredoxin-like. WB:WBGene00007826 C30H6.9 Predicted to be located in membrane. WB:WBGene00007827 trh-1 Expressed in M4 neuron and M5 neuron. WB:WBGene00007829 oac-5 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00007830 C31A11.2 No description available WB:WBGene00007831 srbc-83 Predicted to be located in membrane. WB:WBGene00007832 srbc-82 Predicted to be located in membrane. WB:WBGene00007833 oac-6 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00007834 srxa-7 Predicted to be located in membrane. Expressed in PVT and chemosensory neurons. WB:WBGene00007835 oac-7 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00007836 phdh-1 Predicted to enable phosphoglycerate dehydrogenase activity. Human ortholog(s) of this gene implicated in Neu-Laxova syndrome 1 and PHGDH deficiency. Is an ortholog of human PHGDH (phosphoglycerate dehydrogenase). WB:WBGene00007837 fbxa-167 Enriched in body wall muscle cell; head mesodermal cell; hypodermis; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and sek-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00007838 fbxa-168 Enriched in PLM; Z1; and Z4 based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00007839 C31C9.5 No description available WB:WBGene00007840 C31C9.6 Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be located in cytoplasm. WB:WBGene00007841 C31C9.7 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; male distal tip cell; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00007842 C31E10.1 Enriched in head mesodermal cell and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00007843 C31E10.2 No description available WB:WBGene00007844 irld-24 Enriched in SMBDL; SMBDR; SMBVL; SMBVR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00007846 C31E10.5 Predicted to be involved in Golgi to plasma membrane transport. Is an ortholog of human CCDC93 (coiled-coil domain containing 93). WB:WBGene00007847 C31E10.6 Predicted to be involved in Golgi to plasma membrane transport. Predicted to be located in membrane. Is an ortholog of human CCDC93 (coiled-coil domain containing 93). WB:WBGene00007848 cytb-5.1 Predicted to enable heme binding activity. Located in perinuclear region of cytoplasm. Used to study hematopoietic system disease. Human ortholog(s) of this gene implicated in methemoglobinemia; methemoglobinemia and ambiguous genitalia; and stomatitis. Is an ortholog of human CYB5A (cytochrome b5 type A) and CYB5B (cytochrome b5 type B). WB:WBGene00007849 tbc-19 Predicted to enable GTPase activator activity. WB:WBGene00007850 C31G12.1 Predicted to be located in membrane. WB:WBGene00007851 clec-245 Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including rotenone; Tunicamycin; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00007852 C31G12.3 Is affected by lin-15B; rsr-2; and flcn-1 based on microarray and tiling array studies. Is affected by Atrazine and dafa#1 based on microarray studies. WB:WBGene00007853 C31G12.4 Enriched in arcade cell; germ line; and terminal bulb based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00007854 C31H5.1 Predicted to enable hydrolase activity. WB:WBGene00007855 C31H5.4 Enriched in several structures, including ABplpppaaa; ABprpppaaa; intestine; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including 1-methylnicotinamide; rotenone; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00007856 C31H5.5 Enriched in several structures, including neurons; rectal epithelial cell; rectum; retrovesicular ganglion; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including rotenone; stavudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007857 C31H5.6 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in disease of metabolism. Is an ortholog of several human genes including ACOT2 (acyl-CoA thioesterase 2); ACOT4 (acyl-CoA thioesterase 4); and BAAT (bile acid-CoA:amino acid N-acyltransferase). WB:WBGene00007858 C31H5.7 Enriched in several structures, including ABplpppaaa; I5 neuron; dopaminergic neurons; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007859 mrps-31 Predicted to be a structural constituent of ribosome. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS31 (mitochondrial ribosomal protein S31). WB:WBGene00007860 rilp-1 Predicted to enable dynein light intermediate chain binding activity and small GTPase binding activity. Predicted to be involved in cilium assembly. Predicted to be located in ciliary basal body and cytoplasm. Human ortholog(s) of this gene implicated in oculopharyngodistal myopathy 4. Is an ortholog of human RILPL1 (Rab interacting lysosomal protein like 1). WB:WBGene00007861 C32A9.1 Predicted to be located in membrane. WB:WBGene00007862 kvs-2 Predicted to enable delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26; intracranial hypertension; and retinal cone dystrophy 3B. Is an ortholog of human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1). WB:WBGene00007863 C32C4.3 Predicted to be located in membrane. WB:WBGene00007864 irg-6 Involved in response to gamma radiation. WB:WBGene00007865 srz-15 Predicted to be located in membrane. WB:WBGene00007866 C32H11.3 Enriched in CEPshDL; CEPshDR; CEPshVL; and CEPshVR based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including tryptophan; 1-methylnicotinamide; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00007867 C32H11.4 Involved in innate immune response. WB:WBGene00007868 srlf-4 Enriched in GABAergic neurons; pharynx; and touch receptor neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; nicotinic acid; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00007869 srlf-5 Enriched in g2L; g2R; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; D-glucose; and cholesterol based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00007870 C32H11.7 Enriched in several structures, including ABplpaaaap; ABplpaapap; AFD; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00007871 srlf-6 Is affected by several genes including daf-2; lin-4; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Tunicamycin; multi-walled carbon nanotube; and Diazinon based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00007872 cld-1 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including methylmercury hydroxide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00007873 dod-21 Enriched in FLP and intestine based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; quantitative PCR; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Heme; methylmercury hydroxide; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00007874 C32H11.11 Is affected by several genes including daf-2; eat-2; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00007875 dod-24 Involved in defense response to Gram-negative bacterium. WB:WBGene00007876 dct-19 Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including paraquat; stearic acid; and sucrose based on RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00007877 nfki-1 Predicted to be involved in positive regulation of cell differentiation and regulation of transcription by RNA polymerase II. Expressed in several structures, including nervous system. Is an ortholog of human NFKBIZ (NFKB inhibitor zeta). WB:WBGene00007878 C33A11.2 Predicted to be located in membrane. Expressed in several structures, including CAN; gonad; head; pharyngeal cell; and tail. Human ortholog(s) of this gene implicated in cone-rod dystrophy. Is an ortholog of human DRAM2 (DNA damage regulated autophagy modulator 2). WB:WBGene00007880 ndua-5 Predicted to be involved in respiratory electron transport chain. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human NDUFA5 (NADH:ubiquinone oxidoreductase subunit A5). WB:WBGene00007881 nlp-35 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00007882 C33A12.3 Expressed widely. Is an ortholog of human C4orf33 (chromosome 4 open reading frame 33). WB:WBGene00007883 C33A12.4 Expressed in AVJ and ciliated neurons. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007884 C33A12.5 No description available WB:WBGene00007885 ugt-21 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00007886 ethe-1 Predicted to enable sulfur dioxygenase activity. Predicted to be involved in glutathione metabolic process and hydrogen sulfide metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in ethylmalonic encephalopathy. Is an ortholog of human ETHE1 (ETHE1 persulfide dioxygenase). WB:WBGene00007887 gadr-2 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00007888 ttr-9 Predicted to be located in cell surface and extracellular region. WB:WBGene00007889 C33A12.16 Is affected by clk-1; lin-14; and lin-4 based on microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies. WB:WBGene00007890 C33A12.19 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00007891 C33B4.2 Enriched in AFD; SMD; germline precursor cell; and hypodermis based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercury hydroxide; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00007892 C33B4.4 Enriched in several structures, including germ line; muscle cell; sensory neurons; somatic gonad precursor; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Zidovudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00007893 C33B4.5 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including drh-3; let-418; and wrn-1 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride based on microarray studies. WB:WBGene00007894 C33D3.3 Enriched in muscle cell; neurons; and retrovesicular ganglion based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Tunicamycin; D-glucose; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00007895 C33D3.4 Enriched in ASER based on RNA-seq studies. Is affected by several genes including let-60; rrf-3; and elt-2 based on tiling array; RNA-seq; and microarray studies. Is affected by antimycin and dafa#1 based on RNA-seq and microarray studies. WB:WBGene00007896 C33D3.5 Enriched in AFD; ASER; body wall musculature; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; clk-1; and mex-3 based on microarray and RNA-seq studies. Is affected by tryptophan and Mercuric Chloride based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00007897 clec-182 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and lin-4 based on tiling array; microarray; and RNA-seq studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domain: C-type lectin fold. WB:WBGene00007898 C33D9.3 Enriched in intestine; muscle cell; neurons; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00007899 C33D9.5 Enriched in body wall muscle cell; neurons; and somatic gonad precursor based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including 1-methylnicotinamide; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00007900 C33D9.6 Expressed in hypodermis; muscle cell; and ventral cord neurons. WB:WBGene00007901 C33D9.8 Enriched in body muscle cell; neurons; pharynx; and rectal muscle based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; D-glucose; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00007902 C33D9.9 Enriched in coelomocyte and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including 1-methylnicotinamide; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00007903 lgc-21 Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00007904 C33G3.4 Predicted to enable beta-mannosidase activity. Predicted to be involved in glycoprotein catabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in beta-mannosidosis. Is an ortholog of human MANBA (mannosidase beta). WB:WBGene00007905 C33G3.5 Enriched in germ line; male-specific anatomical entity; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00007906 C33G3.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00007907 C34B4.2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00007908 C34B4.3 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00007909 C34B4.4 Enriched in AFD; PHB; head mesodermal cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; elt-2; and nhr-49 based on tiling array and RNA-seq studies. Is affected by rotenone based on RNA-seq studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00007910 C34B4.5 Predicted to be located in membrane. WB:WBGene00007911 C34B7.1 Enriched in ABplpapppa; arcade cell; dopaminergic neurons; pharyngeal-intestinal valve; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00007912 figo-1 Predicted to enable phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be located in intracellular membrane-bounded organelle. Expressed in GABAergic neurons; body wall musculature; head neurons; intestine; and tail neurons. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 4J; Yunis-Varon syndrome; and amyotrophic lateral sclerosis type 11. Is an ortholog of human FIG4 (FIG4 phosphoinositide 5-phosphatase). WB:WBGene00007913 cyp-36A1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in body wall musculature; intestine; neurons; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2D6 (cytochrome P450 family 2 subfamily D member 6); and CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)). WB:WBGene00007914 mys-4 Predicted to enable histone H4K16 acetyltransferase activity and transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Predicted to be part of MSL complex. Human ortholog(s) of this gene implicated in androgen insensitivity syndrome and breast cancer. Is an ortholog of human KAT7 (lysine acetyltransferase 7). WB:WBGene00007916 C34C6.3 Enriched in epithelial cell; hypodermis; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including aldicarb; Ethanol; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: DOMON domain. WB:WBGene00007917 chdh-1 Predicted to enable oxidoreductase activity. Expressed in gonad. Is an ortholog of human CHDH (choline dehydrogenase). WB:WBGene00007918 sphk-1 Predicted to enable D-erythro-sphingosine kinase activity and acetyltransferase activity. Involved in mitochondrial unfolded protein response; positive regulation of acetylcholine secretion, neurotransmission; and regulation of locomotion. Located in several cellular components, including mitochondrion; neuronal cell body; and presynaptic periactive zone. Expressed in several structures, including body wall musculature; excretory canal; intestine; linker cell; and neurons. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human SPHK1 (sphingosine kinase 1) and SPHK2 (sphingosine kinase 2). WB:WBGene00007919 cup-16 Involved in endocytosis and lysosomal protein catabolic process. Predicted to be located in lysosome. WB:WBGene00007920 C34C12.1 Is affected by several genes including daf-16; daf-12; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1280) and Protein of unknown function DUF1280. WB:WBGene00007921 C34C12.2 Enriched in several structures, including ABalppppaa; ABaraapapp; ABaraapppp; ABplapppaa; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; glp-1; and dpy-10 based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by eleven chemicals including D-glucose; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007922 pph-6 Predicted to enable protein serine/threonine phosphatase activity. Involved in cortical actin cytoskeleton organization; establishment of mitotic spindle localization; and first cell cycle pseudocleavage. Located in astral microtubule and cell cortex. Is an ortholog of human PPP6C (protein phosphatase 6 catalytic subunit). WB:WBGene00007923 C34C12.4 Predicted to be located in endoplasmic reticulum. Expressed in several structures, including gland cell; intestine; marginal cell; non-striated muscle; and spermatheca. Is an ortholog of human SMIM14 (small integral membrane protein 14). WB:WBGene00007924 rsu-1 Involved in innate immune response. Expressed in body wall musculature; distal tip cell; pharyngeal muscle cell; ventral cord neurons; and vulval muscle. Is an ortholog of human RSU1 (Ras suppressor protein 1). WB:WBGene00007925 C34C12.6 Predicted to be located in cytoplasm. WB:WBGene00007926 C34C12.7 Predicted to be located in membrane. WB:WBGene00007927 C34C12.8 Predicted to enable adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrion. Is an ortholog of human GRPEL1 (GrpE like 1, mitochondrial) and GRPEL2 (GrpE like 2, mitochondrial). WB:WBGene00007928 C34C12.9 Enriched in PVT; body wall muscle cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; elt-2; and clk-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Tunicamycin; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00007929 dmd-10 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including male anatomical structure morphogenesis; mechanosensory behavior; and negative regulation of synapse pruning. Predicted to be located in nucleus. Expressed in several structures, including AVG; body wall musculature; head neurons; intestine; and vulval muscle. Is an ortholog of human DMRT1 (doublesex and mab-3 related transcription factor 1) and DMRTC2 (DMRT like family C2). WB:WBGene00007931 C34D1.4 Predicted to enable hydrolase activity. Predicted to be located in membrane. WB:WBGene00007932 zip-5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Expressed in head muscle; head neurons; tail neurons; and ventral nerve cord. WB:WBGene00007933 C34E7.3 Enriched in M cell; head mesodermal cell; nerve ring neurons; rect_D; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and aak-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007934 gmap-1 Enriched in several structures, including ABarpaapap; ABarpaappa; amphid neurons; anterior hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including D-glucose; bisphenol S; and Neurotoxins based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: GM2-AP, lipid-recognition domain superfamily. WB:WBGene00007935 C34E11.2 Predicted to be involved in several processes, including post-embryonic development; regulation of DNA-templated transcription; and regulation of developmental process. WB:WBGene00007937 C34E11.4 Enriched in ABplapppapp; ABprapppapp; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; rotenone; and stavudine based on microarray and RNA-seq studies. WB:WBGene00007938 C34F6.1 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00007939 C34F6.5 Enriched in several structures, including ABalpapppa; ABaraapapp; ABaraapppp; amphid neurons; and pharynx based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Tamoxifen; paraquat; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00007941 C34F6.7 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in endoplasmic reticulum. Is an ortholog of human TMEM129 (transmembrane protein 129, E3 ubiquitin ligase). WB:WBGene00007942 idh-2 Predicted to enable isocitrate dehydrogenase (NADP+) activity. Predicted to be involved in NADP metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including D-2-hydroxyglutaric aciduria 2; gastrointestinal system cancer (multiple); and lung non-small cell carcinoma (multiple). Is an ortholog of human IDH2 (isocitrate dehydrogenase (NADP(+)) 2). WB:WBGene00007943 C34F6.9 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be located in cytosol and nucleus. WB:WBGene00007944 C34F6.10 Predicted to be involved in axon guidance; cell-cell adhesion; and neuron migration. Predicted to be located in axonal growth cone; cell surface; and plasma membrane. Expressed in RIH and body wall musculature. Is an ortholog of human FNDC3A (fibronectin type III domain containing 3A) and FNDC3B (fibronectin type III domain containing 3B). WB:WBGene00007945 C34F6.11 Predicted to be located in membrane. WB:WBGene00007946 ugt-33 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00007947 C35A5.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00007948 C35A5.4 Predicted to be located in cytoskeleton. WB:WBGene00007949 C35A5.5 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00007950 C35A5.6 Predicted to be located in extracellular region. WB:WBGene00007951 dmsr-8 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00007952 C35A5.8 Predicted to enable nuclear export signal receptor activity. Predicted to be involved in protein export from nucleus. Predicted to be located in cytoplasm. Predicted to be part of nuclear pore. Expressed widely. Is an ortholog of human RANBP17 (RAN binding protein 17) and XPO7 (exportin 7). WB:WBGene00007953 hda-11 Predicted to enable histone deacetylase activity. Predicted to be involved in chromatin remodeling. Predicted to be part of histone deacetylase complex. Is an ortholog of human HDAC11 (histone deacetylase 11). WB:WBGene00007954 gcp-2.2 Predicted to enable carboxypeptidase activity. Predicted to be located in membrane. Is an ortholog of human FOLH1 (folate hydrolase 1); NAALAD2 (N-acetylated alpha-linked acidic dipeptidase 2); and NAALADL1 (N-acetylated alpha-linked acidic dipeptidase like 1). WB:WBGene00007955 selt-1.1 Predicted to enable thioredoxin-disulfide reductase (NADP) activity. Predicted to be involved in cell redox homeostasis. Predicted to be located in endoplasmic reticulum membrane. Expressed in several structures, including P5.paaa; amphid neurons; body wall musculature; interfacial epithelial cell; and pharyngeal cell. Is an ortholog of human SELENOT (selenoprotein T). WB:WBGene00007956 trpp-9 Predicted to be located in trans-Golgi network. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 13. Is an ortholog of human TRAPPC9 (trafficking protein particle complex subunit 9). WB:WBGene00007957 C35C5.8 Enriched in dopaminergic neurons; hypodermis; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including rotenone; Tunicamycin; and Ethanol based on RNA-seq and microarray studies. WB:WBGene00007958 C35C5.9 Enriched in AIM; cephalic sheath cell; dopaminergic neurons; hypodermis; and intestine based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including aldicarb; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00007959 C35C5.10 Predicted to be located in membrane. Is an ortholog of human TMEM164 (transmembrane protein 164). WB:WBGene00007960 C35D6.3 Enriched in ABalppappa; ABarappppa; ADEL; and ADER based on single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and cat-2 based on microarray and RNA-seq studies. Is affected by stavudine and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: PAZ domain superfamily. WB:WBGene00007961 C35D6.4 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein); ZFP36L1 (ZFP36 ring finger protein like 1); and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00007962 C35D6.5 Is affected by several genes including daf-2; nhr-49; and hsp-6 based on RNA-seq and microarray studies. Is affected by eight chemicals including multi-walled carbon nanotube; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00007963 cyp-25A1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. WB:WBGene00007964 cyp-25A2 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. WB:WBGene00007965 C36A4.4 Predicted to enable uridylyltransferase activity. Predicted to be located in cytoplasm. Is an ortholog of human UAP1 (UDP-N-acetylglucosamine pyrophosphorylase 1) and UAP1L1 (UDP-N-acetylglucosamine pyrophosphorylase 1 like 1). WB:WBGene00007966 maph-1.3 Predicted to enable actin binding activity and microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization; neuron projection development; and regulation of microtubule depolymerization. Predicted to be located in several cellular components, including cytosol; microtubule; and somatodendritic compartment. Predicted to be part of microtubule associated complex. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness and periventricular nodular heterotopia. Is an ortholog of human MAP1A (microtubule associated protein 1A); MAP1B (microtubule associated protein 1B); and MAP1S (microtubule associated protein 1S). WB:WBGene00007967 cyp-25A4 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. WB:WBGene00007968 C36A4.7 No description available WB:WBGene00007969 acs-19 Predicted to enable acetate-CoA ligase activity. Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and regulation of response to oxidative stress. Expressed in hypodermis; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in lymphangioleiomyomatosis; morbid obesity; and orofacial cleft. Is an ortholog of human ACSS2 (acyl-CoA synthetase short chain family member 2). WB:WBGene00007970 C36A4.10 Enriched in several structures, including AVK; GLR; MSpppaaa; head mesodermal cell; and intestine based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by hydrogen sulfide and Sirolimus based on microarray studies. WB:WBGene00007971 rpb-3 Predicted to enable DNA-directed 5'-3' RNA polymerase activity and protein dimerization activity. Predicted to contribute to RNA polymerase II activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be part of RNA polymerase II, core complex. Is an ortholog of human POLR2C (RNA polymerase II subunit C). WB:WBGene00007972 prp-4 Predicted to enable U4 snRNA binding activity and U6 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nuclear speck. Predicted to be part of U4/U6 x U5 tri-snRNP complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa 70. Is an ortholog of human PRPF4 (pre-mRNA processing factor 4). WB:WBGene00007973 C36B1.6 Predicted to be located in membrane. WB:WBGene00007974 dhfr-1 Predicted to enable NADP binding activity and dihydrofolate reductase activity. Predicted to be involved in dihydrofolate metabolic process; folic acid metabolic process; and tetrahydrofolate biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia. Is an ortholog of human DHFR (dihydrofolate reductase); DHFR2 (dihydrofolate reductase 2); and DHFRP1 (dihydrofolate reductase pseudogene 1). WB:WBGene00007975 gls-1 Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in mRNA 3'-end processing. Located in P granule. Part of polysome. Expressed in germ line. WB:WBGene00007976 C36B1.9 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. WB:WBGene00007977 gskl-2 Predicted to enable MAP kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and nucleus. Expressed in germ line; gonad; and sperm. WB:WBGene00007978 C36B1.11 Enriched in germ line; germline precursor cell; head mesodermal cell; and head neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by fourteen chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00007979 imp-1 Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in membrane protein proteolysis. Predicted to be located in organelle membrane and plasma membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human SPPL2A (signal peptide peptidase like 2A); SPPL2B (signal peptide peptidase like 2B); and SPPL2C (signal peptide peptidase like 2C). WB:WBGene00007980 tif-1A Predicted to enable RNA polymerase I core binding activity and RNA polymerase I general transcription initiation factor activity. Predicted to be involved in transcription initiation at RNA polymerase I promoter. Predicted to be located in nucleus. Is an ortholog of human RRN3 (RRN3 homolog, RNA polymerase I transcription factor). WB:WBGene00007981 glb-11 Predicted to enable heme binding activity and oxygen binding activity. Expressed in neurons; pharynx; and somatic nervous system. WB:WBGene00007982 pxd-1 Predicted to be located in membrane. Expressed in head; muscle cell; and tail. Is an ortholog of human PLXDC2 (plexin domain containing 2). WB:WBGene00007983 C36E8.4 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in positive regulation of JNK cascade; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein ubiquitination. Is an ortholog of human NOSTRIN (nitric oxide synthase trafficking). WB:WBGene00007984 irx-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell development; neuron differentiation; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in head muscle; hypodermis; intestine; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Is an ortholog of several human genes including IRX1 (iroquois homeobox 1); IRX3 (iroquois homeobox 3); and IRX5 (iroquois homeobox 5). WB:WBGene00007985 swah-1 Predicted to be involved in positive regulation of protein catabolic process and protein ubiquitination. Expressed in intestine. WB:WBGene00007986 C36F7.5 Predicted to be located in membrane. WB:WBGene00007987 C36H8.1 Predicted to be located in cytoskeleton and membrane. WB:WBGene00007988 best-8 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00007989 fipr-22 Predicted to be involved in innate immune response. WB:WBGene00007990 fipr-23 Predicted to be involved in innate immune response. WB:WBGene00007991 C37A5.7 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00007992 fipr-24 Acts upstream of or within IRE1-mediated unfolded protein response. WB:WBGene00007993 idhb-1 Predicted to enable isocitrate dehydrogenase (NAD+) activity and metal ion binding activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to be located in mitochondrion. Expressed in head. Human ortholog(s) of this gene implicated in retinitis pigmentosa 46. Is an ortholog of human IDH3B (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta). WB:WBGene00007994 C37E2.2 Predicted to be located in endomembrane system. Is an ortholog of human ADTRP (androgen dependent TFPI regulating protein). WB:WBGene00007995 C37E2.3 Predicted to be located in endomembrane system. Is an ortholog of human ADTRP (androgen dependent TFPI regulating protein) and AIG1 (androgen induced 1). WB:WBGene00007996 C38C6.3 Enriched in PLM; body wall musculature; germline precursor cell; and hypodermis based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-two chemicals including methylmercury hydroxide; 1-methylnicotinamide; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00007997 sre-13 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00007998 C38C6.5 Enriched in PLM and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00007999 tag-297 Expressed in head neurons and hypodermis. WB:WBGene00008000 slc-17.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in sialuria. Is an ortholog of human SLC17A5 (solute carrier family 17 member 5). WB:WBGene00008001 C38C10.3 Enriched in amphid sheath cell; germ line; hypodermis; and in male based on proteomic; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including methylmercuric chloride; D-glucose; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF508 and Domain of unknown function (DUF508). WB:WBGene00008002 nlp-48 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00008003 enu-3.2 Predicted to be involved in axon extension involved in axon guidance. Predicted to be located in neuronal cell body. WB:WBGene00008005 mip-1 Expressed in several structures, including Psub3; Psub4; Z2; Z3; and spermatocyte. WB:WBGene00008006 tag-325 Predicted to be involved in signal transduction. Predicted to be located in cytoplasm. Is an ortholog of human ARHGAP12 (Rho GTPase activating protein 12); ARHGAP27 (Rho GTPase activating protein 27); and ARHGAP9 (Rho GTPase activating protein 9). WB:WBGene00008007 C38D4.7 Enriched in several structures, including DB neuron; PVT; germ line; rect_D; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including glp-1; hsf-1; and elt-2 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including rotenone; mianserin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00008008 metl-5 Enables rRNA (adenine-N6-)-methyltransferase activity. Involved in positive regulation of translation in response to stress and rRNA base methylation. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 72. Is an ortholog of human METTL5 (methyltransferase 5, N6-adenosine). WB:WBGene00008009 fbxa-171 Enriched in neurons and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00008010 C38D9.2 Expressed in intestinal cell. WB:WBGene00008011 C38D9.3 No description available WB:WBGene00008012 fbxa-133 Is affected by several genes including daf-16; daf-2; and let-60 based on microarray and RNA-seq studies. Is affected by Ethanol; Atrazine; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00008013 C38D9.5 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-7 based on RNA-seq; microarray; and proteomic studies. Is affected by five chemicals including cholesterol; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00008014 fbxa-172 Is affected by several genes including daf-2; eat-2; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Alovudine; stavudine; and Rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00008015 fbxa-174 Enriched in DA neuron; VA neuron; body wall muscle cell; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00008016 C38D9.8 Enriched in B cell; hypodermis; and rect_D based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-18; and mex-3 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00008017 fbxa-176 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; antimycin; and paraquat based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00008018 tbc-8 Enables small GTPase binding activity. Involved in dense core granule maturation. Located in Golgi cisterna; cytosol; and early endosome. Expressed in neurons. Is an ortholog of human SGSM2 (small G protein signaling modulator 2). WB:WBGene00008019 C38H2.2 Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Expressed in several structures, including tail. Is an ortholog of human C1GALT1 (core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1). WB:WBGene00008020 C38H2.3 Predicted to be located in membrane. WB:WBGene00008021 C39B10.1 Predicted to be located in membrane. WB:WBGene00008022 lgc-41 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00008023 C39B10.3 Enriched in several structures, including intestine; male distal tip cell; muscle cell; neurons; and somatic gonad precursor based on SAGE; tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; let-60; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including tryptophan; metformin; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00008024 C39B10.4 Enriched in NSM; Z1; Z4; coelomocyte; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; drh-3; and smg-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008025 C39B10.5 Enriched in neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; hpl-2; and dpy-21 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00008026 scl-4 Is affected by several genes including daf-16; daf-2; and ung-1 based on microarray and tiling array studies. WB:WBGene00008027 scl-5 Predicted to be located in extracellular space. Expressed in pharyngeal gland cell. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00008028 scl-6 Predicted to be located in extracellular space. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00008029 scl-7 Predicted to be located in extracellular space. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00008030 scl-8 Predicted to be located in extracellular space. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00008031 C39E9.7 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00008032 C39E9.8 Enriched in several structures, including MSaapapa; MSpapapa; arc ant V; g2; and germline precursor cell based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-eight chemicals including 1-methylnicotinamide; D-glucose; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00008033 spin-2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 115. Is an ortholog of human SPNS1 (SPNS lysolipid transporter 1, lysophospholipid); SPNS2 (SPNS lysolipid transporter 2, sphingosine-1-phosphate); and SPNS3 (SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)). WB:WBGene00008034 prcc-1 Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in papillary renal cell carcinoma. Is an ortholog of human PRCC (proline rich mitotic checkpoint control factor). WB:WBGene00008035 C39E9.12 Enriched in several structures, including ABplapaaapa; ABplapppapp; ABprapaaapa; ciliated neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SAP domain superfamily and SAP domain. WB:WBGene00008036 C40C9.3 Enriched in anterior spermatheca; coelomocyte; head mesodermal cell; and posterior spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008037 C40C9.4 Is affected by several genes including sir-2.1; clk-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube; fluoranthene; and Diazinon based on RNA-seq and microarray studies. WB:WBGene00008038 C40H1.2 Enriched in RIML; RIMR; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including tryptophan; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00008039 C40H1.3 Enriched in neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in Joubert syndrome 25 and autosomal recessive intellectual developmental disorder 77. Is an ortholog of human CEP104 (centrosomal protein 104). WB:WBGene00008040 ttr-5 Predicted to be located in cell surface and extracellular region. WB:WBGene00008041 ufc-1 Enables ubiquitin conjugating enzyme binding activity. Predicted to be involved in protein ufmylation. Located in striated muscle dense body. Expressed in intestine and neurons. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with spasticity and poor growth. Is an ortholog of human UFC1 (ubiquitin-fold modifier conjugating enzyme 1). WB:WBGene00008042 C40H1.7 Predicted to be involved in lipid metabolic process. WB:WBGene00008043 C40H1.8 Predicted to be involved in lipid metabolic process. WB:WBGene00008044 C40H1.9 Predicted to be involved in lipid metabolic process. WB:WBGene00008045 C40H5.2 Predicted to enable calcium ion binding activity. Predicted to be located in membrane. WB:WBGene00008047 lact-7 Enriched in several structures, including ABalpppappp; enteric muscle; interfacial epithelial cell; rectum; and somatic gonad precursor based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including D-glucose; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Beta-lactamase; Beta-lactamase/transpeptidase-like; Beta-lactamase-related; and Bacterial tandem repeat domain 1. WB:WBGene00008048 hpo-41 Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008050 chst-1 Enables chondroitin 4-sulfotransferase activity. Involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in Golgi membrane. WB:WBGene00008051 lron-4 Enriched in neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; sir-2.1; and pgl-1 based on microarray; RNA-seq; and proteomic studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily; Leucine-rich repeat, typical subtype; Leucine rich repeat; and Leucine-rich repeat. WB:WBGene00008052 ctns-1 Predicted to enable L-cystine transmembrane transporter activity. Involved in L-cystine transport; lysosome organization; and phagocytosis. Located in lysosomal membrane. Used to study cystinosis. Human ortholog(s) of this gene implicated in cystinosis. Is an ortholog of human CTNS (cystinosin, lysosomal cystine transporter). WB:WBGene00008053 cdc-48.2 Enables ATP hydrolysis activity and identical protein binding activity. Involved in several processes, including ER-associated misfolded protein catabolic process; negative regulation of protein localization to centrosome; and protein localization to nucleus. Located in nucleus. Part of VCP-NPL4-UFD1 AAA ATPase complex. Expressed in body wall musculature and germ line. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2Y; frontotemporal dementia and/or amyotrophic lateral sclerosis-6; and inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 1. Is an ortholog of human VCP (valosin containing protein). WB:WBGene00008054 C41C4.9 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including hpl-2; egl-43; and etr-1 based on tiling array and RNA-seq studies. WB:WBGene00008055 cyp-34A3 Enriched in CEM; HOB; IL2 neuron; and ray neuron type B based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and smg-2 based on tiling array; RNA-seq; and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00008056 nhr-164 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008057 irld-25 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; mut-2; and mir-34 based on microarray and RNA-seq studies. Is affected by resveratrol and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00008058 C41G6.12 Predicted to be located in membrane. WB:WBGene00008059 C41G6.13 Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including mianserin; nanoparticle; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008060 C41G6.16 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and hpl-2 based on tiling array and microarray studies. WB:WBGene00008061 mina-1 Enables mRNA 3'-UTR binding activity. Acts upstream of or within with a positive effect on negative regulation of apoptotic process and negative regulation of gene expression, epigenetic. Predicted to be located in cytoplasm and nucleus. Expressed in oocyte. WB:WBGene00008062 set-32 Enriched in several structures, including Z1.p; germ line; germline precursor cell; head mesodermal cell; and male distal tip cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; glp-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including manganese chloride; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SET domain superfamily and SET domain. WB:WBGene00008063 cylc-2 Expressed in nervous system and sperm. WB:WBGene00008064 C41G7.7 Enriched in head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-7 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; Chlorpyrifos; and Diazinon based on RNA-seq and microarray studies. WB:WBGene00008065 npr-18 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in ASER. WB:WBGene00008066 fbxb-65 Enriched in several structures, including ABalppappa; ABalpppapa; ABalppppaa; ABalpppppa; and ciliated neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including methylmercuric chloride; multi-walled carbon nanotube; and bisphenol S based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00008067 C43D7.4 Enriched in neuronal sheath cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Mercuric Chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00008068 sdz-6 Involved in gastrulation. WB:WBGene00008069 C43D7.7 Is affected by several genes including daf-2; skn-1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and Psoralens based on RNA-seq studies. WB:WBGene00008070 C43D7.8 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ciliated neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including bisphenol S; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00008071 fbxb-64 Is affected by several genes including daf-2; eat-2; and drh-3 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00008072 C43F9.4 Predicted to be located in membrane. WB:WBGene00008073 C43F9.5 Enriched in g1AL; g1AR; and g1P based on single-cell RNA-seq studies. Is affected by several genes including let-60; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including tryptophan; rotenone; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Cysteine-rich repeat. WB:WBGene00008074 nkb-2 Predicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Human ortholog(s) of this gene implicated in several diseases, including atrophic gastritis; autoimmune gastritis; and essential hypertension. Is an ortholog of several human genes including ATP1B1 (ATPase Na+/K+ transporting subunit beta 1); ATP1B2 (ATPase Na+/K+ transporting subunit beta 2); and ATP1B3 (ATPase Na+/K+ transporting subunit beta 3). WB:WBGene00008075 C43F9.7 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00008076 lgc-43 Predicted to enable neurotransmitter receptor activity. Predicted to contribute to GABA-A receptor activity and chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Predicted to be part of GABA-A receptor complex. WB:WBGene00008077 oac-8 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00008078 vps-50 Predicted to enable SNARE binding activity. Involved in positive regulation of dense core granule transport and positive regulation of locomotion involved in locomotory behavior. Predicted to be located in cytosol. Predicted to be part of EARP complex. Is an ortholog of human VPS50 (VPS50 subunit of EARP/GARPII complex). WB:WBGene00008079 C44B9.2 Enriched in excretory gland cell; germ line; germline precursor cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-7 based on RNA-seq; tiling array; microarray; and proteomic studies. Is affected by fourteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00008080 C44B9.3 Predicted to be located in membrane. WB:WBGene00008081 athp-1 Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Sin3-type complex. Is an ortholog of human PHF12 (PHD finger protein 12). WB:WBGene00008082 com-1 Predicted to enable damaged DNA binding activity. Predicted to be involved in DNA double-strand break processing involved in repair via single-strand annealing. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Seckel syndrome 2. Is an ortholog of human RBBP8 (RB binding protein 8, endonuclease). WB:WBGene00008083 cyp-29A1 Enriched in AVK and sensory neurons based on RNA-seq studies. Is affected by several genes including clk-1; hpl-2; and cyc-1 based on microarray and RNA-seq studies. WB:WBGene00008084 C44C10.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00008085 smcl-1 Predicted to enable DNA binding activity. Predicted to be involved in sister chromatid cohesion. Predicted to be located in nucleus. Predicted to be part of cohesin complex. Expressed in germ line. WB:WBGene00008086 C44C10.5 Enriched in several structures, including AVG; AWC; germ line; male distal tip cell; and motor neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00008087 C44C10.6 Is affected by clk-1 and sir-2.1 based on microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies. WB:WBGene00008088 C44C10.7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00008089 C44C10.9 Predicted to be located in membrane. WB:WBGene00008090 C44C10.10 Predicted to enable ATP hydrolysis activity. Predicted to be involved in double-strand break repair. Predicted to be located in membrane. WB:WBGene00008091 C44F1.1 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABprpaaapa; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00008092 gmeb-3 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and metal ion binding activity. Predicted to be involved in DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Is an ortholog of human GMEB1 (glucocorticoid modulatory element binding protein 1) and GMEB2 (glucocorticoid modulatory element binding protein 2). WB:WBGene00008093 lron-1 Predicted to be located in membrane. Expressed in pharynx. Is an ortholog of human LRRC15 (leucine rich repeat containing 15). WB:WBGene00008094 C44H4.4 Expressed in head. Human BLTP3B enables GARP complex binding activity; lipid transfer activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Bridge-like lipid transfer protein family member 3A/B; N-terminal region of Chorein or VPS13; and Phosphorylation site. Is an ortholog of human BLTP3A (bridge-like lipid transfer protein family member 3A) and BLTP3B (bridge-like lipid transfer protein family member 3B). WB:WBGene00008095 C44H4.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway and signal transduction. Predicted to be located in axon; cytosol; and nucleus. WB:WBGene00008096 C44H4.8 Predicted to be located in membrane. WB:WBGene00008097 ugt-15 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00008098 C44H9.2 Is affected by drh-3; etr-1; and eat-2 based on RNA-seq and microarray studies. Is affected by resveratrol; Atrazine; and allantoin based on microarray studies. WB:WBGene00008099 C44H9.4 Predicted to enable RNA binding activity. WB:WBGene00008100 C44H9.5 Predicted to be located in membrane. WB:WBGene00008101 C44H9.6 Predicted to be located in membrane. WB:WBGene00008102 C44H9.7 Predicted to be located in membrane. WB:WBGene00008104 B0395.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00008105 C45B11.2 Enriched in AFD; amphid sheath cell; and pharynx based on microarray and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008106 C45B11.5 Predicted to be located in membrane. WB:WBGene00008107 aspm-1 Enables calmodulin binding activity and protein domain specific binding activity. Involved in establishment of meiotic spindle orientation; meiotic spindle organization; and regulation of protein localization. Located in spindle midzone and spindle pole. Used to study microcephaly. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); primary autosomal recessive microcephaly 5; and visual epilepsy. Is an ortholog of human ASPM (assembly factor for spindle microtubules). WB:WBGene00008110 C46C2.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SVOPL (SVOP like). WB:WBGene00008111 C46C2.3 Enriched in several structures, including ADE sheath cell; AFD; AIA; germ line; and pharyngeal neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; rotenone; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00008112 C46C2.4 Enriched in AVK based on RNA-seq studies. Is affected by several genes including let-60; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00008113 C46C2.5 Enriched in germ line and hypodermis based on proteomic and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; rotenone; and Alovudine based on microarray; RNA-seq; and proteomic studies. WB:WBGene00008114 C46C2.6 Enriched in several structures, including AVH; G2; body wall muscle cell from C lineage; germ line; and touch receptor neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00008117 gsr-1 Enables glutathione-disulfide reductase (NADP) activity. Involved in several processes, including cell redox homeostasis; ecdysis, collagen and cuticulin-based cuticle; and response to superoxide. Located in cytosol and mitochondrion. Expressed in several structures, including Epr; Epra; coelomocyte; excretory canal; and hermaphrodite gonad. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; cataract (multiple); hematologic cancer (multiple); and hemolytic anemia (multiple). Is an ortholog of human GSR (glutathione-disulfide reductase). WB:WBGene00008118 madf-8 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. WB:WBGene00008119 C46F11.4 Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in myelodysplastic syndrome. Is an ortholog of human DDX42 (DEAD-box helicase 42). WB:WBGene00008120 C46F11.5 Predicted to be located in membrane. Expressed in body wall musculature. WB:WBGene00008121 C46F11.6 Predicted to be located in plasma membrane. Is an ortholog of human UBL3 (ubiquitin like 3). WB:WBGene00008122 C47A4.1 Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human DNAJC25 (DnaJ heat shock protein family (Hsp40) member C25) and DNAJC25-GNG10 (DNAJC25-GNG10 readthrough). WB:WBGene00008123 ent-4 Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Is an ortholog of human SLC29A2 (solute carrier family 29 member 2) and SLC29A3 (solute carrier family 29 member 3). WB:WBGene00008124 C47A4.3 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00008125 C47A4.5 Enriched in amphid sheath cell; intestine; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including aldicarb; methylmercuric chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00008126 sre-21 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ADLL; ADLR; and hypodermis. WB:WBGene00008127 ddo-1 Enables D-aspartate oxidase activity; D-glutamate oxidase activity; and FAD binding activity. Involved in obsolete oxidation-reduction process. Predicted to be located in cytoplasm. Expressed in hypodermis and intestinal cell. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human DAO (D-amino acid oxidase). WB:WBGene00008128 srab-12 Predicted to be located in membrane. Expressed in head and neurons. WB:WBGene00008129 C47A10.12 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00008130 fbxa-140 Enriched in AFD; NSM; germ line; and seam cell based on RNA-seq studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00008131 C47B2.2 Predicted to enable glycosyltransferase activity. Located in striated muscle dense body. Is an ortholog of human UPRT (uracil phosphoribosyltransferase homolog). WB:WBGene00008132 gale-1 Enables UDP-N-acetylglucosamine 4-epimerase activity and UDP-glucose 4-epimerase activity. Involved in several processes, including gonad morphogenesis; negative regulation of endoplasmic reticulum unfolded protein response; and positive regulation of vulval development. Predicted to be located in cytosol. Expressed in head. Used to study galactosemia. Human ortholog(s) of this gene implicated in galactose epimerase deficiency. Is an ortholog of human GALE (UDP-galactose-4-epimerase). WB:WBGene00008133 efsc-1 Predicted to enable translation elongation factor activity. Involved in selenocysteine incorporation. Is an ortholog of human EEFSEC (eukaryotic elongation factor, selenocysteine-tRNA specific). WB:WBGene00008134 C47B2.9 Predicted to enable RNA binding activity. Predicted to be involved in regulation of mitochondrial transcription. Predicted to be located in mitochondrion. Is an ortholog of human MTRES1 (mitochondrial transcription rescue factor 1). WB:WBGene00008135 B0491.t1 No description available WB:WBGene00008136 C47D12.2 Predicted to be involved in Golgi organization. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Smith-McCort dysplasia 1. Is an ortholog of human DYM (dymeclin). WB:WBGene00008137 sfxn-1.4 Predicted to enable serine transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Predicted to be located in mitochondrial membrane. Is an ortholog of human SFXN1 (sideroflexin 1) and SFXN3 (sideroflexin 3). WB:WBGene00008138 C47D12.4 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; pharyngeal cell; and rectum based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00008139 C47D12.5 Predicted to be located in membrane. WB:WBGene00008140 xpf-1 Enables enzyme binding activity. Involved in DNA damage response; meiotic chromosome segregation; and regulation of multicellular organismal development. Predicted to be part of nucleotide-excision repair factor 1 complex. Expressed in body wall musculature; embryonic cell; germ cell; and neurons. Used to study Cockayne syndrome; Fanconi anemia; and xeroderma pigmentosum. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia complementation group Q; XFE progeroid syndrome; and polyneuropathy due to drug. Is an ortholog of human ERCC4 (ERCC excision repair 4, endonuclease catalytic subunit). WB:WBGene00008141 C47E8.1 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; D-glucose; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008142 C47E8.3 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00008143 C47E8.4 Predicted to be involved in chromatin organization. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Armfield syndrome. Is an ortholog of human FAM50A (family with sequence similarity 50 member A) and FAM50B (family with sequence similarity 50 member B). WB:WBGene00008144 gasr-8 Predicted to enable microtubule binding activity and small GTPase binding activity. Predicted to be involved in cell motility. Located in ciliary basal body. Expressed in amphid neurons; ciliated neurons; head neurons; sensory neurons; and tail neurons. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 33. Is an ortholog of human GAS8 (growth arrest specific 8). WB:WBGene00008145 set-5 Enriched in germ line; germline precursor cell; head mesodermal cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including glp-1; dpy-10; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twelve chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SET domain superfamily; Domain of unknown function (DUF545); SET domain; and SPK domain. WB:WBGene00008146 C47E8.9 Enriched in arcade cell; neurons; pharyngeal cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by five chemicals including Tunicamycin; multi-walled carbon nanotube; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00008147 C47E12.2 Predicted to enable ATP:ADP antiporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. WB:WBGene00008148 C47E12.3 Predicted to enable calcium ion binding activity and mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum. Expressed in head neurons. Is an ortholog of human EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1). WB:WBGene00008149 pyp-1 Predicted to enable inorganic diphosphate phosphatase activity. Involved in innate immune response. Located in neuron projection and vacuole. Expressed in coelomocyte and neurons. Is an ortholog of human PPA1 (inorganic pyrophosphatase 1) and PPA2 (inorganic pyrophosphatase 2). WB:WBGene00008150 mam-2 Predicted to be located in membrane. WB:WBGene00008151 rrp-1 Predicted to be involved in rRNA processing. Predicted to be located in nucleus. Predicted to be part of preribosome, small subunit precursor. Is an ortholog of human RRP1 (ribosomal RNA processing 1). WB:WBGene00008152 C47E12.9 Enriched in PLM and amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; bisphenol A; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00008153 C47E12.10 Predicted to be located in membrane. WB:WBGene00008154 C47E12.11 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00008155 C47E12.12 Predicted to be located in membrane. WB:WBGene00008156 C47E12.13 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and anterior hypodermis based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and alg-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00008157 C47F8.1 Enriched in several structures, including ABalppappa; ABarappppa; ABarpaaa; accessory cell; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; sir-2.1; and pmk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00008158 nhr-165 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in hyp7 syncytium and seam cell. WB:WBGene00008159 C47F8.3 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. WB:WBGene00008160 glct-4 Predicted to enable galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity. Predicted to be involved in carbohydrate metabolic process and chondroitin sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in Barrett's esophagus and schizophrenia. Is an ortholog of human B3GAT1 (beta-1,3-glucuronyltransferase 1) and B3GAT2 (beta-1,3-glucuronyltransferase 2). WB:WBGene00008161 C47F8.5 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. WB:WBGene00008162 C47F8.6 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. WB:WBGene00008163 C47F8.7 Enriched in intestine and pharyngeal muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and csr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Tunicamycin; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00008164 C47G2.3 Predicted to enable mitochondrion targeting sequence binding activity and protein transmembrane transporter activity. Predicted to be involved in protein insertion into mitochondrial inner membrane. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM22 mitochondrial import inner membrane insertion complex. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 43. Is an ortholog of human TIMM22 (translocase of inner mitochondrial membrane 22). WB:WBGene00008165 C47G2.4 Predicted to be located in membrane. Is an ortholog of human LMBRD2 (LMBR1 domain containing 2). WB:WBGene00008166 saps-1 Enables protein phosphatase binding activity. Involved in cortical actin cytoskeleton organization; establishment of mitotic spindle localization; and first cell cycle pseudocleavage. Located in astral microtubule and cell cortex. Is an ortholog of human PPP6R3 (protein phosphatase 6 regulatory subunit 3). WB:WBGene00008167 acox-1.5 Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in pheromone biosynthetic process. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1). WB:WBGene00008168 C48B4.3 Enriched in several structures, including ABalaappppa; ABalapaappa; excretory gland cell; head mesodermal cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00008169 C48B4.6 Enriched in Psub1; germ line; germline precursor cell; head mesodermal cell; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5373 and Family of unknown function (DUF5373). WB:WBGene00008170 C48B4.7 Enriched in AFD; DVC; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5373 and Family of unknown function (DUF5373). WB:WBGene00008171 C48B4.8 Predicted to be located in membrane. WB:WBGene00008172 C48B4.9 Enriched in several structures, including AFD; ALN; germ line; posterior arcade cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and gld-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5373 and Family of unknown function (DUF5373). WB:WBGene00008173 C48B4.10 Predicted to be located in membrane. WB:WBGene00008174 C48B4.11 Enriched in arcade cell; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and gld-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; manganese chloride; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00008175 C48B4.12 Enriched in germ line; male-specific anatomical entity; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00008176 C48B4.13 Enriched in several structures, including PVP; XXX cell; accessory cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including 1-methylnicotinamide; methylmercuric chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00008177 C48D1.1 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00008178 C48D1.5 Predicted to be located in membrane. WB:WBGene00008179 B0491.t2 No description available WB:WBGene00008180 C48D5.3 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; PLM; head mesodermal cell; and rect_D based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including metformin; Sirolimus; and antimycin based on RNA-seq and microarray studies. WB:WBGene00008183 rin-1 Enables GTPase binding activity. Involved in dorsal/ventral axon guidance and neuron migration. Located in cell periphery; cytoplasm; and filopodium. Expressed in body wall musculature; gonad; head neurons; and hypodermis. Is an ortholog of human RIN2 (Ras and Rab interactor 2). WB:WBGene00008184 C49A1.1 Predicted to be located in membrane. WB:WBGene00008185 best-10 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. WB:WBGene00008186 best-11 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00008187 C49A1.5 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00008188 clec-115 Is affected by eat-2; etr-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by resveratrol; Chlorpyrifos; and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; C-type lectin-like/link domain superfamily; and PAN-3 domain. WB:WBGene00008189 C49A1.8 No description available WB:WBGene00008190 clec-114 Enriched in CEM; HOB; IL2 neuron; and ray neuron type B based on RNA-seq studies. Is affected by several genes including csr-1; drh-3; and etr-1 based on tiling array and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; and PAN-3 domain. WB:WBGene00008191 C49A1.10 Predicted to be located in lysosomal membrane. Expressed in body wall musculature. WB:WBGene00008192 C49C3.2 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including manganese chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008193 C49C3.3 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and glh-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00008194 C49C3.4 Enriched in AFD; AINL; AINR; head mesodermal cell; and intestine based on SAGE; tiling array; RNA-seq; single-cell RNA-seq; and proteomic studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on proteomic; RNA-seq; and microarray studies. Is affected by sixteen chemicals including mianserin; nicotine; and Zidovudine based on RNA-seq; proteomic; and microarray studies. WB:WBGene00008195 ceh-88 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Expressed in several structures, including excretory cell; hyp12; neurons; tail hypodermis; and ventral nerve cord. WB:WBGene00008196 C49C3.6 Enriched in AFD; AIML; AIMR; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and npr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00008197 C49C3.7 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABprpaaapa; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00008198 C49C3.8 Enriched in several structures, including body wall muscle cell; excretory cell; germ line; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Alovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008199 C49C3.9 Involved in defense response to Gram-negative bacterium and innate immune response. WB:WBGene00008200 C49C3.10 Predicted to enable MAP kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and nucleus. WB:WBGene00008201 C49C3.11 Enriched in germ line; male-specific anatomical entity; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including skn-1; daf-12; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00008202 clec-197 Expressed in male gonad. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00008203 clec-198 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-2; isp-1; and lin-15B based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; D-glucose; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00008204 C49C3.15 Enriched in anterior ganglion; intestine; neurons; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and glh-1 based on microarray and RNA-seq studies. Is affected by Humic Substances and Sirolimus based on microarray studies. WB:WBGene00008205 sams-1 Predicted to enable methionine adenosyltransferase activity. Involved in negative regulation of lipid storage. Predicted to be located in cytosol. Expressed in body wall musculature; dorsal nerve cord; and ventral nerve cord. Used to study lipid metabolism disorder. Human ortholog(s) of this gene implicated in hypermethioninemia and lung cancer. Is an ortholog of human MAT1A (methionine adenosyltransferase 1A) and MAT2A (methionine adenosyltransferase 2A). WB:WBGene00008206 set-6 Enables histone H3K9 dimethyltransferase activity and histone H3K9 trimethyltransferase activity. Predicted to be involved in chromatin remodeling and methylation. Part of chromatin. Expressed in embryonic cell; gonad; muscle cell; nervous system; and sperm. Is an ortholog of human SUV39H2 (SUV39H2 histone lysine methyltransferase). WB:WBGene00008207 C49F5.3 Predicted to be located in membrane. WB:WBGene00008208 nhr-167 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008209 C49F5.5 Predicted to enable histone acetyltransferase activity and metal ion binding activity. Predicted to be involved in chromatin remodeling and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008210 C49F5.6 Enriched in several structures, including ABalpppapa; NSM; germ line; male distal tip cell; and rect_D based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including D-glucose; bisphenol A; and Psoralens based on RNA-seq; microarray; and proteomic studies. WB:WBGene00008211 C49F5.7 Enriched in ALN; NSM; germ line; hypodermis; and intestine based on tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by twenty-three chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00008212 C49F5.8 Enriched in coelomocyte; excretory gland cell; intestine; and rectal epithelium based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including pgl-1; csr-1; and atfs-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Colistin based on microarray studies. WB:WBGene00008213 C49F8.1 Enriched in arcade cell; ciliated neurons; pharynx; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by aldicarb and paraquat based on microarray and RNA-seq studies. WB:WBGene00008214 gem-1 Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Located in plasma membrane. Expressed in several structures, including hermaphrodite distal tip cell; neurons; pharynx; somatic gonad precursor; and vulval muscle. WB:WBGene00008215 C49F8.3 Enriched in PLM; germline precursor cell; hypodermis; seam cell; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00008216 mec-19 Predicted to be located in membrane. Expressed in mechanosensory neurons. WB:WBGene00008217 C50B6.1 Enriched in muscle cell based on microarray studies. Is affected by several genes including cye-1; cdk-2; and mir-34 based on tiling array and microarray studies. Is affected by dibromoacetic acid and adsorbable organic bromine compound based on microarray studies. WB:WBGene00008218 nasp-2 Predicted to enable histone binding activity. Predicted to be involved in CENP-A containing chromatin assembly and DNA replication-dependent chromatin assembly. Predicted to be located in nucleoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in ovarian cancer. Is an ortholog of human NASP (nuclear autoantigenic sperm protein). WB:WBGene00008219 C50B6.3 Enriched in several structures, including ABalapapap; ABalapppap; ABplpaaapp; AVA; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on proteomic; microarray; and RNA-seq studies. Is affected by fifteen chemicals including manganese chloride; D-glucose; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008220 C50B6.7 Predicted to enable alpha-amylase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in extracellular space. Expressed in intestine. Is an ortholog of human AMY2A (amylase alpha 2A) and AMY2B (amylase alpha 2B). WB:WBGene00008221 nhr-168 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00008222 C50B6.9 Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to be located in endosome membrane and plasma membrane. Is an ortholog of human ABHD10 (abhydrolase domain containing 10, depalmitoylase). WB:WBGene00008223 lgc-48 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00008224 slrp-1 Predicted to enable RNA binding activity. Is an ortholog of human SLIRP (SRA stem-loop interacting RNA binding protein). WB:WBGene00008225 nuaf-1 Predicted to enable unfolded protein binding activity. Involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 11. Is an ortholog of human NDUFAF1 (NADH:ubiquinone oxidoreductase complex assembly factor 1). WB:WBGene00008226 C50B8.4 Predicted to be located in membrane. WB:WBGene00008227 C50B8.5 Predicted to be located in membrane. WB:WBGene00008228 C50B8.6 Predicted to be located in membrane. WB:WBGene00008229 C50F4.1 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00008230 pfk-1.2 Predicted to enable several functions, including 6-phosphofructokinase activity; carbohydrate derivative binding activity; and identical protein binding activity. Predicted to be involved in canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and fructose 6-phosphate metabolic process. Predicted to be located in cytoplasm. Predicted to be part of 6-phosphofructokinase complex. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Is an ortholog of human PFKL (phosphofructokinase, liver type); PFKM (phosphofructokinase, muscle); and PFKP (phosphofructokinase, platelet). WB:WBGene00008231 tag-329 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. WB:WBGene00008232 C50F4.4 Expressed in head neurons; tail neurons; touch receptor neurons; and ventral nerve cord. WB:WBGene00008233 C50F4.8 Involved in defense response to Gram-positive bacterium. WB:WBGene00008234 C50F4.9 Involved in innate immune response. WB:WBGene00008235 C50F4.10 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00008236 C50F4.12 Predicted to enable double-stranded DNA binding activity. Predicted to be involved in mitochondrial ribosome assembly and mitochondrial transcription. Predicted to be located in mitochondrion. Is an ortholog of human MTERF3 (mitochondrial transcription termination factor 3). WB:WBGene00008237 nstp-10 Predicted to enable GDP-fucose transmembrane transporter activity and antiporter activity. Predicted to be involved in GDP-fucose import into Golgi lumen. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIc. Is an ortholog of human SLC35C1 (solute carrier family 35 member C1). WB:WBGene00008238 C50F4.16 Predicted to enable UDP-sugar diphosphatase activity. Predicted to be involved in nucleoside phosphate metabolic process and ribose phosphate metabolic process. Is an ortholog of human NUDT14 (nudix hydrolase 14). WB:WBGene00008239 fshr-1 Predicted to enable G protein-coupled peptide receptor activity. Involved in defense response to other organism; response to oxidative stress; and stress response to cadmium ion. Predicted to be located in plasma membrane. Expressed in intestine; neurons; pharynx; spermatheca; and vulva. Human ortholog(s) of this gene implicated in several diseases, including cystadenocarcinoma (multiple); disorder of sexual development (multiple); and sex cord-gonadal stromal tumor (multiple). Is an ortholog of human FSHR (follicle stimulating hormone receptor) and LHCGR (luteinizing hormone/choriogonadotropin receptor). WB:WBGene00008240 C50H2.4 Enriched in Z1.p; Z4.a; male distal tip cell; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008241 C50H2.5 Enriched in AIM; sensory neurons; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00008242 ceh-75 Predicted to enable DNA binding activity. Predicted to be located in nucleus. Expressed in dorsal nerve cord and head neurons. WB:WBGene00008243 C50H2.7 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00008244 fipr-11 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including aldicarb; D-glucose; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00008245 fipr-10 Enriched in Z1; Z4; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including Ethanol; D-glucose; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00008246 C50H2.13 Predicted to be located in membrane. WB:WBGene00008247 srsx-26 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of human OR2L2 (olfactory receptor family 2 subfamily L member 2). WB:WBGene00008248 srsx-27 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in ASIL and ASIR. Is an ortholog of several human genes including OR2M4 (olfactory receptor family 2 subfamily M member 4); OR5H1 (olfactory receptor family 5 subfamily H member 1); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00008249 srsx-28 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in chemosensory neurons and cholinergic neurons. Is an ortholog of several human genes including OR2M4 (olfactory receptor family 2 subfamily M member 4); OR5H1 (olfactory receptor family 5 subfamily H member 1); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00008250 srsx-29 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in ADFL; ADFR; PHAL; and PHAR. Is an ortholog of several human genes including OR2M4 (olfactory receptor family 2 subfamily M member 4); OR5H1 (olfactory receptor family 5 subfamily H member 1); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00008251 srsx-30 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in GABAergic neurons; I4 neuron; and head. Is an ortholog of several human genes including OR2B6 (olfactory receptor family 2 subfamily B member 6); OR2M4 (olfactory receptor family 2 subfamily M member 4); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00008252 C51E3.6 Predicted to enable L-ascorbic acid transmembrane transporter activity. Predicted to be involved in L-ascorbic acid transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC23A2 (solute carrier family 23 member 2). WB:WBGene00008253 C51E3.8 Is affected by several genes including clk-1; lin-39; and adr-1 based on RNA-seq; tiling array; and microarray studies. Is affected by estrogen and Acrylamide based on microarray studies. WB:WBGene00008254 C51E3.9 Predicted to enable hexaprenyldihydroxybenzoate methyltransferase activity. Predicted to be involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. WB:WBGene00008255 C51E3.10 Predicted to be located in membrane. WB:WBGene00008256 glb-12 Predicted to enable heme binding activity; metal ion binding activity; and oxygen binding activity. Expressed in hermaphrodite gonad; neurons; and vulva. WB:WBGene00008257 C52A11.3 Enriched in ASI; AVE; RID; neurons; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; cyc-1; and mir-34 based on microarray; tiling array; and RNA-seq studies. Is affected by Ag nanoparticles based on RNA-seq studies. Is predicted to encode a protein with the following domains: PDZ domain 6; PDZ domain; and PDZ superfamily. WB:WBGene00008258 mans-2 Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in carbohydrate metabolic process and protein glycosylation. Predicted to be located in Golgi membrane and endoplasmic reticulum. Is an ortholog of human MAN1A2 (mannosidase alpha class 1A member 2). WB:WBGene00008259 C52E4.7 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00008260 C52G5.2 Enriched in several structures, including PLM; germline precursor cell; hypodermis; interfacial epithelial cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including aldicarb; D-glucopyranose; and D-glucose based on microarray; RNA-seq; and proteomic studies. Human THAP4 enables several functions, including heme binding activity; identical protein binding activity; and peroxynitrite isomerase activity. Is predicted to encode a protein with the following domains: Calycin; THAP4-like, heme-binding beta-barrel domain; and Nitrobindin family. Is an ortholog of human THAP4 (THAP domain containing 4). WB:WBGene00008261 C52G5.3 Enriched in neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including drh-3; unc-70; and spc-1 based on RNA-seq studies. Is affected by tryptophan and Cry5B based on microarray studies. WB:WBGene00008262 ril-1 Predicted to be located in membrane. WB:WBGene00008263 C53A5.2 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; germ line; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00008265 kcnl-4 Predicted to enable calmodulin binding activity and small conductance calcium-activated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in neuron projection; neuronal cell body; and plasma membrane. Is an ortholog of human KCNN1 (potassium calcium-activated channel subfamily N member 1). WB:WBGene00008266 rike-1 Predicted to enable metal ion binding activity. WB:WBGene00008267 C53A5.9 Enriched in several structures, including ABalpapaap; ABarappaap; intestine; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; Mercuric Chloride; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Kelch-type beta propeller; Kelch repeat type 1; and Kelch motif. WB:WBGene00008268 srt-32 Predicted to be located in membrane. WB:WBGene00008269 C53A5.11 Enriched in cholinergic neurons and pharyngeal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including skn-1; lin-4; and lin-14 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Galactose oxidase/kelch, beta-propeller; Kelch-type beta propeller; Kelch repeat type 1; and Kelch motif. WB:WBGene00008270 C53A5.13 Predicted to be located in membrane. WB:WBGene00008271 suex-2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00008272 C53B4.2 Enriched in AFD; AVK; coelomocyte; and in male based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; age-1; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF851); Protein of unknown function DUF851; and Phosphorylation site. WB:WBGene00008273 C53B4.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in nucleus. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple) and breast cancer. Is an ortholog of human SLC22A18 (solute carrier family 22 member 18). WB:WBGene00008274 pdzd-8 Predicted to enable lipid binding activity. Predicted to be involved in mitochondrial calcium ion homeostasis and mitochondrion-endoplasmic reticulum membrane tethering. Predicted to be located in mitochondria-associated endoplasmic reticulum membrane. Is an ortholog of human PDZD8 (PDZ domain containing 8). WB:WBGene00008275 nstp-1 Predicted to enable UDP-N-acetylglucosamine transmembrane transporter activity and UDP-xylose transmembrane transporter activity. Predicted to be involved in UDP-N-acetylglucosamine transmembrane transport and UDP-xylose transmembrane transport. Predicted to be located in endomembrane system and membrane. Is an ortholog of human SLC35B4 (solute carrier family 35 member B4). WB:WBGene00008277 mltn-12 Enriched in ABalpapaap; ABarappaap; hypodermis; intestine; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercury hydroxide; Tunicamycin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Moulting cycle MLT-10-like protein and Moulting cycle. WB:WBGene00008278 npr-10 Predicted to enable neuropeptide binding activity and neuropeptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection and plasma membrane. Expressed in RMEV; ciliated neurons; and ganglia. Human ortholog(s) of this gene implicated in artery disease (multiple); lipid metabolism disorder; and obesity. Is an ortholog of human PRLHR (prolactin releasing hormone receptor). WB:WBGene00008279 C53C7.3 Enriched in ABplpaapap; ABprpaapap; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00008280 acc-2 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Predicted to be part of chloride channel complex. Expressed in neurons. WB:WBGene00008281 C53D6.4 Predicted to be involved in cilium assembly. Predicted to be located in cilium. Human ortholog(s) of this gene implicated in Meckel syndrome. Is an ortholog of human TXNDC15 (thioredoxin domain containing 15). WB:WBGene00008282 C53D6.5 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including tryptophan; multi-walled carbon nanotube; and glycine based on microarray and RNA-seq studies. WB:WBGene00008283 C53D6.6 Predicted to enable protein dimerization activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human ZBED1 (zinc finger BED-type containing 1). WB:WBGene00008284 C53D6.7 Predicted to enable galactoside binding activity. WB:WBGene00008285 C53D6.8 Enriched in germ line and terminal bulb based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00008286 C54C6.4 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00008287 C54C6.5 Enriched in neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including unc-30; csr-1; and atfs-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008288 C54C6.6 Predicted to be involved in cilium assembly; positive regulation of feeding behavior; and regulation of cell motility. Predicted to be located in microtubule cytoskeleton and motile cilium. Is an ortholog of human CFAP20 (cilia and flagella associated protein 20). WB:WBGene00008289 nhr-169 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008290 bgnt-1.8 Expressed in seam cell. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A13. Human B4GAT1 enables glucuronosyltransferase activity. Is predicted to encode a protein with the following domain: Glycosyl-transferase for dystroglycan. Is an ortholog of human B4GAT1 (beta-1,4-glucuronyltransferase 1). WB:WBGene00008291 C54C8.3 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. WB:WBGene00008292 C54C8.4 Predicted to enable transferase activity. Predicted to be located in membrane. WB:WBGene00008293 glct-5 Predicted to enable galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity. Predicted to be involved in carbohydrate metabolic process and chondroitin sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in Barrett's esophagus and schizophrenia. Is an ortholog of human B3GAT1 (beta-1,3-glucuronyltransferase 1) and B3GAT2 (beta-1,3-glucuronyltransferase 2). WB:WBGene00008294 clec-11 Is affected by several genes including eat-2; sir-2.1; and sek-1 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including methylmercuric chloride; Tunicamycin; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00008295 nlp-39 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00008296 cdr-2 Involved in regulation of protein deneddylation and stress response to cadmium ion. Predicted to be located in cytoplasm. WB:WBGene00008297 cdr-3 Involved in stress response to cadmium ion. Predicted to be located in cytoplasm. WB:WBGene00008298 C54D10.3 Enriched in OLL; PVD; RIBL; and RIBR based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; rotenone; and mianserin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00008299 C54D10.4 Predicted to be located in membrane. WB:WBGene00008300 C54D10.5 Predicted to be located in membrane. Expressed in anal depressor muscle; head muscle; lateral ganglion; retrovesicular ganglion neurons; and ventral ganglion. WB:WBGene00008301 pals-39 Enriched in DA neuron; VA neuron; dopaminergic neurons; and intestine based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Tunicamycin; D-glucose; and stavudine based on microarray and RNA-seq studies. WB:WBGene00008302 pals-38 Enriched in body wall muscle cell; intestine; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including Mercuric Chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00008303 C54D10.9 Enriched in several structures, including ABplaapaaa; ABpraapaaa; AFD; IL socket cell; and Y cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and aak-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Rifampin; and bortezomib based on RNA-seq and microarray studies. WB:WBGene00008304 C54D10.10 Predicted to enable serine-type endopeptidase inhibitor activity. Human ortholog(s) of this gene implicated in acute myeloid leukemia and retinal degeneration. Is an ortholog of human TFPI2 (tissue factor pathway inhibitor 2). WB:WBGene00008306 C54E10.1 Enriched in AFD; ASER; AVK; and neurons based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Alovudine; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00008307 ncs-5 Predicted to enable calcium ion binding activity. Expressed in body wall musculature and head neurons. Is an ortholog of human KCNIP1 (potassium voltage-gated channel interacting protein 1). WB:WBGene00008308 C54E10.3 Predicted to be located in membrane. WB:WBGene00008309 nhr-170 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008310 C54E10.6 Enriched in several structures, including head mesodermal cell; muscle cell; neurons; rectal muscle; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; pgl-1; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00008311 rskn-2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleoplasm. Is an ortholog of human RPS6KA4 (ribosomal protein S6 kinase A4) and RPS6KA5 (ribosomal protein S6 kinase A5). WB:WBGene00008312 C54G4.2 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00008313 C54G4.3 Enriched in germ line and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00008314 C54G4.4 Enriched in several structures, including ABalaapppa; ABalapaaaa; RIA; arcade cell; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including stavudine; Zidovudine; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin-like; C-type lectin-like/link domain superfamily; Sushi/SCR/CCP superfamily; Galactose-binding-like domain superfamily; Sushi/SCR/CCP domain; C-type lectin fold; and Sushi repeat (SCR repeat). WB:WBGene00008315 C54G4.5 Predicted to be located in membrane. WB:WBGene00008316 dod-18 Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of human ASMTL (acetylserotonin O-methyltransferase like). WB:WBGene00008317 C54G4.7 Predicted to enable hydrolase activity. Is an ortholog of human ABHD18 (abhydrolase domain containing 18). WB:WBGene00008318 C54G4.9 Enriched in several structures, including ABaraapapp; ABaraapppp; ABplpaaaap; AVK; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including manganese chloride; allantoin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00008319 C54G10.1 Is affected by several genes including daf-2; rrf-3; and lin-4 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Tunicamycin; Sodium Chloride; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00008320 slc-25A29 Predicted to enable high-affinity L-arginine transmembrane transporter activity. Predicted to be involved in mitochondrial L-ornithine transmembrane transport. Predicted to be located in mitochondrion. Is an ortholog of human SLC25A29 (solute carrier family 25 member 29). WB:WBGene00008321 C55A1.1 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00008322 C55A1.4 Is affected by several genes including daf-16; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including aldicarb; Rifampin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00008323 C55A1.6 Enriched in several structures, including GLR; MSpppaaa; coelomocyte; excretory system; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-7 based on microarray; proteomic; and RNA-seq studies. Is affected by thirteen chemicals including Mercuric Chloride; Sodium Chloride; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00008324 C55A1.7 Enriched in coelomocyte and head mesodermal cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by Rifampin; allantoin; and nitroguanidine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00008325 C55A1.9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and mut-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008326 C55A1.11 Enriched in AVA; germ line; and neurons based on tiling array and RNA-seq studies. Is affected by rsr-2; etr-1; and ain-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00008327 srz-44 Predicted to be located in membrane. WB:WBGene00008328 srz-43 Enriched in neurons based on RNA-seq studies. Is affected by clk-1 and sams-3 based on microarray and RNA-seq studies. WB:WBGene00008330 C55A6.1 Predicted to enable poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human RNF146 (ring finger protein 146). WB:WBGene00008331 ttll-5 Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Involved in response to hermaphrodite contact. Predicted to be located in cilium. Human ortholog(s) of this gene implicated in cone-rod dystrophy 19. Is an ortholog of human TTLL5 (tubulin tyrosine ligase like 5). WB:WBGene00008332 C55A6.3 Predicted to enable oxidoreductase activity. Predicted to be located in cytoplasm. Is an ortholog of human CBR3 (carbonyl reductase 3). WB:WBGene00008333 C55A6.4 Predicted to enable oxidoreductase activity. Predicted to be located in cytoplasm. Is an ortholog of human CBR3 (carbonyl reductase 3). WB:WBGene00008334 sdz-8 Predicted to enable oxidoreductase activity. Predicted to be located in cytoplasm. Is an ortholog of human CBR3 (carbonyl reductase 3). WB:WBGene00008335 C55A6.6 Predicted to enable oxidoreductase activity. Predicted to be located in cytoplasm. Is an ortholog of human CBR3 (carbonyl reductase 3). WB:WBGene00008336 C55A6.7 Predicted to enable oxidoreductase activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in cytoplasm. Is an ortholog of human CBR3 (carbonyl reductase 3). WB:WBGene00008337 C55A6.8 Is affected by rsr-2; daf-2; and sir-2.1 based on tiling array and microarray studies. WB:WBGene00008338 pafo-1 Predicted to enable RNA polymerase II complex binding activity and chromatin binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Located in nucleus. Is an ortholog of human PAF1 (PAF1 homolog, Paf1/RNA polymerase II complex component). WB:WBGene00008339 C55A6.10 Located in striated muscle dense body. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 66. Is an ortholog of human C12orf4 (chromosome 12 open reading frame 4). WB:WBGene00008340 C55A6.11 Predicted to be located in membrane. WB:WBGene00008341 ttr-44 Predicted to be located in cell surface and extracellular region. WB:WBGene00008342 frpr-5 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00008343 C56A3.4 Predicted to enable ubiquitin-protein transferase activity. Predicted to be located in membrane. Is an ortholog of human RNF26 (ring finger protein 26). WB:WBGene00008344 C56A3.5 Enriched in body wall muscle cell and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00008345 C56A3.6 Predicted to enable calcium ion binding activity. Predicted to be involved in calcium import into the mitochondrion and mitochondrial calcium ion homeostasis. Predicted to be part of uniplex complex. Is an ortholog of human MICU3 (mitochondrial calcium uptake family member 3). WB:WBGene00008346 C56A3.8 Predicted to enable 1-phosphatidylinositol 4-kinase activity. Predicted to be involved in Golgi organization; endosome organization; and phosphatidylinositol phosphate biosynthetic process. Predicted to be located in endosome; plasma membrane; and trans-Golgi network. Is an ortholog of human PI4K2A (phosphatidylinositol 4-kinase type 2 alpha) and PI4K2B (phosphatidylinositol 4-kinase type 2 beta). WB:WBGene00008348 elmd-1 Enriched in head mesodermal cell and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Lithium Chloride; stavudine; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness and autosomal recessive nonsyndromic deafness 88. Is predicted to encode a protein with the following domains: ELMO/CED-12 family and ELMO domain. Is an ortholog of human ELMOD3 (ELMO domain containing 3). WB:WBGene00008349 CE7X_3.1 Is affected by several genes including pgl-1; nhr-49; and unc-30 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; D-glucose; and tert-Butylhydroperoxide based on RNA-seq studies. WB:WBGene00008350 CE7X_3.2 Enriched in DA neuron; VA neuron; and intestine based on tiling array studies. Is affected by several genes including daf-16; hsf-1; and let-7 based on microarray; proteomic; and RNA-seq studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00008351 cTel7X.1 Is affected by tatn-1; smg-2; and eat-2 based on RNA-seq studies. Is affected by Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00008352 fbxa-6 Enriched in dopaminergic neurons; intestine; mechanosensory neurons; and rectal epithelium based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including levamisole; stavudine; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00008353 D1025.1 Enriched in NSM; muscle cell; and sensory neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by single-walled carbon nanotube and paraquat based on microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008354 gcsh-1 Predicted to be involved in glycine decarboxylation via glycine cleavage system. Predicted to be located in mitochondrion. Predicted to be part of glycine cleavage complex. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and multiple mitochondrial dysfunctions syndrome. Is an ortholog of human GCSH (glycine cleavage system protein H). WB:WBGene00008355 fbxa-141 Enriched in head mesodermal cell; interneuron; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including stavudine; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00008356 nspc-20 Enriched in excretory gland cell and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; mianserin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00008357 nspc-16 Enriched in excretory gland cell and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including hydrogen sulfide; Ethanol; and mianserin based on microarray and RNA-seq studies. WB:WBGene00008358 nspc-18 Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; mianserin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00008359 nspc-17 Enriched in NSM and excretory gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; mianserin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00008360 nspc-19 Enriched in excretory gland cell and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including Ethanol; mianserin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00008361 ints-7 Predicted to be involved in snRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of integrator complex. Is an ortholog of human INTS7 (integrator complex subunit 7). WB:WBGene00008362 cfim-2 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA alternative polyadenylation. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is an ortholog of human CPSF7 (cleavage and polyadenylation specific factor 7). WB:WBGene00008363 D1046.2 Enriched in AFD; germ line; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eleven chemicals including manganese chloride; D-glucose; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00008364 slc-25A26 Predicted to enable S-adenosyl-L-methionine transmembrane transporter activity. Predicted to be involved in S-adenosyl-L-methionine transmembrane transport. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 28. Is an ortholog of human SLC25A26 (solute carrier family 25 member 26). WB:WBGene00008365 D1046.4 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00008366 tpra-1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in head neurons and tail. Is an ortholog of human TPRA1 (transmembrane protein adipocyte associated 1). WB:WBGene00008367 D1053.2 Predicted to enable histone H3K79 methyltransferase activity. Predicted to be involved in DNA damage checkpoint signaling and DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in acute biphenotypic leukemia. Is an ortholog of human DOT1L (DOT1 like histone lysine methyltransferase). WB:WBGene00008368 D1053.3 Enriched in amphid neurons; head mesodermal cell; intestine; and pharyngeal neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including Mercuric Chloride; rotenone; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: P-loop containing nucleoside triphosphate hydrolase. WB:WBGene00008369 D1053.4 Predicted to enable transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to be located in membrane. WB:WBGene00008370 D1054.1 Predicted to enable triglyceride lipase activity. Predicted to be involved in lipid homeostasis and triglyceride catabolic process. Predicted to be located in cytoplasm; lipid droplet; and membrane. Is an ortholog of human PNPLA4 (patatin like phospholipase domain containing 4). WB:WBGene00008371 D1054.3 Predicted to enable protein-folding chaperone binding activity. Is an ortholog of human SUGT1 (SGT1 homolog, MIS12 kinetochore complex assembly cochaperone). WB:WBGene00008372 D1054.5 Enriched in OLL; PVD; dopaminergic neurons; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; age-1; and elt-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00008373 D1054.6 Is affected by several genes including clk-1; smg-2; and hmg-3 based on microarray and RNA-seq studies. WB:WBGene00008374 clec-220 Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride and Ketamine based on microarray and RNA-seq studies. WB:WBGene00008375 D1054.8 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00008376 D1054.9 Enriched in several structures, including alimentary muscle; anterior arcade cell; head mesodermal cell; pharyngeal-intestinal valve; and somatic gonad precursor based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00008377 D1054.10 Enriched in several structures, including cephalic sheath cell; germ line; neurons; somatic gonad precursor; and spermatheca based on Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; proteomic; and tiling array studies. Is affected by eighteen chemicals including Heme; Ethanol; and manganese chloride based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008378 ule-3 Enriched in several structures, including MSpppaaa; cephalic sheath cell; germ line; head mesodermal cell; and spermatheca based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; proteomic; and tiling array studies. Is affected by nineteen chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq; proteomic; and microarray studies. WB:WBGene00008379 secs-1 Enables identical protein binding activity. Predicted to be involved in selenocysteine incorporation. Predicted to be located in cytoplasm. Expressed in head neurons and ventral nerve cord. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2D. Is an ortholog of human SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase). WB:WBGene00008380 prp-38 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of precatalytic spliceosome. Is an ortholog of human PRPF38A (pre-mRNA processing factor 38A). WB:WBGene00008381 D1081.3 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; manganese chloride; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Peptidase S1, PA clan; Nematode trypsin-6-like family; Chymotrypsin family Peptidase-S1; and Peptidase S1, PA clan, chymotrypsin-like fold. WB:WBGene00008382 D1081.4 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Rap protein signal transduction and negative regulation of cell migration. Predicted to be located in plasma membrane. WB:WBGene00008383 D1081.5 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00008384 D1081.6 Enriched in several structures, including ABalaappppa; ABalapaappa; germ line; interfacial epithelial cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including mianserin; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00008385 lotr-1 Enriched in ABalaaaala; ABalaapaaa; germ line; germline precursor cell; and head mesodermal cell based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008386 cdc-5L Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Prp19 complex and spliceosomal complex. Human ortholog(s) of this gene implicated in esophagus adenocarcinoma and osteosarcoma. Is an ortholog of human CDC5L (cell division cycle 5 like). WB:WBGene00008387 zhp-2 Predicted to enable SUMO transferase activity. Predicted to be involved in homologous chromosome pairing at meiosis and protein sumoylation. Predicted to be located in synaptonemal complex. Human ortholog(s) of this gene implicated in spermatogenic failure 62. Is an ortholog of human RNF212 (ring finger protein 212) and RNF212B (ring finger protein 212B). WB:WBGene00008388 D1086.1 Enriched in ALM; PLM; and muscle cell based on microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including hydrogen sulfide; tryptophan; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00008389 D1086.2 Enriched in arcade cell; germ line; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by seventeen chemicals including tryptophan; Sodium Chloride; and tert-Butylhydroperoxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00008390 D1086.3 Enriched in several structures, including ABalapppaa; ABarpapaaa; AVJ; cephalic sheath cell; and male distal tip cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirty-eight chemicals including Heme; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; Domain of unknown function (DUF19); and Phosphorylation site. WB:WBGene00008392 D1086.5 Enriched in several structures, including MSaapaapa; MSpapaapa; head mesodermal cell; mechanosensory neurons; and muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00008393 D1086.6 Enriched in anterior spermatheca; cephalic sheath cell; dopaminergic neurons; hypodermis; and posterior spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00008394 D1086.7 Predicted to be located in membrane. WB:WBGene00008395 D1086.8 Enriched in body wall muscle cell; dopaminergic neurons; hypodermis; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00008396 D1086.9 Enriched in cephalic sheath cell; dopaminergic neurons; and hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; multi-walled carbon nanotube; and Ag nanoparticles based on RNA-seq and microarray studies. WB:WBGene00008397 D2005.1 Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to be located in cytoplasm and nucleolus. WB:WBGene00008398 D2005.3 Predicted to enable DNA binding activity. Predicted to be located in cytosol and nucleus. Is an ortholog of human PDCD5 (programmed cell death 5). WB:WBGene00008399 D2005.4 Enriched in germ line; germline precursor cell; head mesodermal cell; and pharynx based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including manganese chloride; stavudine; and Zidovudine based on RNA-seq; proteomic; and microarray studies. WB:WBGene00008400 drh-3 Enables several functions, including ATP hydrolysis activity; ATP-dependent activity, acting on RNA; and RNA binding activity. Involved in P granule assembly; regulatory ncRNA-mediated post-transcriptional gene silencing; and siRNA processing. Located in P granule; condensed nuclear chromosome; and metaphase plate. Expressed widely. Is an ortholog of human RIGI (RNA sensor RIG-I). WB:WBGene00008401 D2005.6 Predicted to be located in membrane. WB:WBGene00008402 wdfy-2 Predicted to enable phosphatidylinositol-3-phosphate binding activity. Involved in endocytosis. Predicted to be located in early endosome. Is an ortholog of human WDFY1 (WD repeat and FYVE domain containing 1) and WDFY2 (WD repeat and FYVE domain containing 2). WB:WBGene00008403 csa-1 Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and transcription-coupled nucleotide-excision repair. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex and nucleotide-excision repair complex. Used to study Cockayne syndrome. Human ortholog(s) of this gene implicated in Cockayne syndrome A and UV-sensitive syndrome. Is an ortholog of human ERCC8 (ERCC excision repair 8, CSA ubiquitin ligase complex subunit). WB:WBGene00008404 wbp-2 Predicted to enable chromatin DNA binding activity and transcription coactivator activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 107. Is an ortholog of human WBP2 (WW domain binding protein 2). WB:WBGene00008405 ttll-12 Predicted to enable ATP binding activity. Involved in egg-laying behavior. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Is an ortholog of human TTLL12 (tubulin tyrosine ligase like 12). WB:WBGene00008407 D2023.3 Enriched in excretory system; intestine; neurons; somatic gonad precursor; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Sodium Chloride; Rifampin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Synaptotagmin-14/14L/16; C2 domain; C2 domain superfamily; and Phosphorylation site. WB:WBGene00008408 D2023.4 Enables N-acetyltransferase activity. Is an ortholog of human SAT1 (spermidine/spermine N1-acetyltransferase 1) and SAT2 (spermidine/spermine N1-acetyltransferase family member 2). WB:WBGene00008409 mpst-1 Predicted to enable thiosulfate sulfurtransferase activity. Predicted to be located in mitochondrion. Is an ortholog of human MPST (mercaptopyruvate sulfurtransferase). WB:WBGene00008410 D2023.6 Predicted to enable kinase activity. Predicted to be involved in lipid homeostasis and mitochondrion organization. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human ADCK1 (aarF domain containing kinase 1). WB:WBGene00008411 mans-1 Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in Golgi membrane and endoplasmic reticulum. Is an ortholog of human MAN1A1 (mannosidase alpha class 1A member 1). WB:WBGene00008412 D2030.2 Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in erythropoietic protoporphyria. Is an ortholog of human CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit X). WB:WBGene00008413 D2030.3 Located in nucleus. WB:WBGene00008414 ndub-7 Predicted to be located in mitochondrial inner membrane; mitochondrial intermembrane space; and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Is an ortholog of human NDUFB7 (NADH:ubiquinone oxidoreductase subunit B7). WB:WBGene00008415 mce-1 Predicted to enable methylmalonyl-CoA epimerase activity. Predicted to be involved in L-methylmalonyl-CoA metabolic process. Located in mitochondrion. Expressed in body wall musculature; hypodermis; intestine; and pharynx. Used to study methylmalonic acidemia. Is an ortholog of human MCEE (methylmalonyl-CoA epimerase). WB:WBGene00008417 D2030.7 Expressed in head neurons. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008418 D2030.8 Predicted to enable transferase activity. Is an ortholog of human PCED1A (PC-esterase domain containing 1A) and PCED1B (PC-esterase domain containing 1B). WB:WBGene00008419 wdr-23 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of cellular response to manganese ion; and proteasome-mediated ubiquitin-dependent protein catabolic process. Located in several cellular components, including intracellular membrane-bounded organelle; neuronal cell body; and striated muscle dense body. Expressed in ASIL; ASIR; head; muscle cell; and tail. Is an ortholog of human DCAF11 (DDB1 and CUL4 associated factor 11). WB:WBGene00008420 D2030.11 Enriched in several structures, including ABplpaaaaa; ABplppaaaap; I5 neuron; cholinergic neurons; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Alovudine; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00008421 D2030.12 Predicted to be located in membrane. WB:WBGene00008422 ecps-1 Predicted to enable molecular adaptor activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome complex. Is an ortholog of human ECPAS (Ecm29 proteasome adaptor and scaffold). WB:WBGene00008423 D2045.5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00008424 D2045.7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in Golgi apparatus. Is an ortholog of human STK16 (serine/threonine kinase 16). WB:WBGene00008425 D2045.8 Predicted to be involved in protein homooligomerization. Is an ortholog of human KCTD10 (potassium channel tetramerization domain containing 10); KCTD13 (potassium channel tetramerization domain containing 13); and TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00008426 D2045.9 Predicted to enable procollagen galactosyltransferase activity. Human ortholog(s) of this gene implicated in brain small vessel disease 3. Is an ortholog of human COLGALT1 (collagen beta(1-O)galactosyltransferase 1) and COLGALT2 (collagen beta(1-O)galactosyltransferase 2). WB:WBGene00008427 atg-10 Predicted to enable ubiquitin-like protein transferase activity. Involved in autophagy. Predicted to be located in phagophore assembly site. Is an ortholog of human ATG10 (autophagy related 10). WB:WBGene00008428 eif-2Bepsilon Predicted to enable guanyl-nucleotide exchange factor activity; translation initiation factor activity; and translation initiation factor binding activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter 5. Is an ortholog of human EIF2B5 (eukaryotic translation initiation factor 2B subunit epsilon). WB:WBGene00008429 etc-1 Enables ubiquitin protein ligase activity. Involved in positive regulation of metaphase/anaphase transition of meiotic cell cycle; regulation of metaphase/anaphase transition of meiosis II; and ubiquitin-dependent protein catabolic process. Is an ortholog of human UBE3C (ubiquitin protein ligase E3C). WB:WBGene00008430 hgap-2 Predicted to enable GTPase activator activity. Involved in determination of adult lifespan. Expressed in pharyngeal muscle cell. Is an ortholog of human RALGAPB (Ral GTPase activating protein non-catalytic subunit beta). WB:WBGene00008431 piga-1 Predicted to enable phosphatidylinositol N-acetylglucosaminyltransferase activity. Predicted to be located in membrane. Predicted to be part of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 2 and paroxysmal nocturnal hemoglobinuria. Is an ortholog of human PIGA (phosphatidylinositol glycan anchor biosynthesis class A). WB:WBGene00008432 D2085.7 Predicted to be involved in autophagosome assembly. Predicted to be located in phagophore assembly site. WB:WBGene00008433 marc-2 Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in membrane. Is an ortholog of human MARCHF1 (membrane associated ring-CH-type finger 1) and MARCHF2 (membrane associated ring-CH-type finger 2). WB:WBGene00008434 D2089.3 Enriched in several structures, including ABaraapapaa; excretory cell; germ line; neurons; and pharyngeal cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including mianserin; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cysteine-rich DPF motif domain-containing protein 1. WB:WBGene00008435 glna-2 Predicted to enable glutaminase activity. Predicted to be involved in glutamate biosynthetic process and glutamine catabolic process. Predicted to be located in mitochondrion. Expressed in head neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 71 and lymphangioleiomyomatosis. Is an ortholog of human GLS (glutaminase). WB:WBGene00008436 DH11.2 Enriched in several structures, including RIS; body wall muscle cell from C lineage; body wall muscle cell from MS lineage; carbon dioxide sensory neurons; and head mesodermal cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including 1-methylnicotinamide; rotenone; and D-glucopyranose based on RNA-seq and microarray studies. WB:WBGene00008438 DH11.5 Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Predicted to be involved in cellular response to calcium ion; regulation of secretion by cell; and synaptic vesicle cycle. Predicted to be located in axon; plasma membrane; and secretory vesicle. WB:WBGene00008439 mfb-1 Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm and nucleus. Predicted to be part of SCF ubiquitin ligase complex. Expressed in several structures, including head; hypodermal cell; tail; touch receptor neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Is an ortholog of human FBXO25 (F-box protein 25) and FBXO32 (F-box protein 32). WB:WBGene00008440 DY3.8 Predicted to be involved in carbohydrate transport. Predicted to be located in membrane. WB:WBGene00008441 usp-50 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in proteolysis. Predicted to be located in early endosome. Human ortholog(s) of this gene implicated in ACTH-secreting pituitary adenoma. Is an ortholog of human USP8 (ubiquitin specific peptidase 8). WB:WBGene00008442 E01B7.2 Predicted to enable transcription coregulator activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008443 pde-3 Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity. Involved in several processes, including determination of adult lifespan; negative regulation of cGMP-mediated signaling; and response to alkaline pH. Human ortholog(s) of this gene implicated in hypertension and brachydactyly syndrome. Is an ortholog of human PDE3A (phosphodiesterase 3A) and PDE3B (phosphodiesterase 3B). WB:WBGene00008444 tbc-14 Predicted to enable GTPase activator activity. Predicted to be located in cytoplasm. Is an ortholog of human TBC1D15 (TBC1 domain family member 15) and TBC1D17 (TBC1 domain family member 17). WB:WBGene00008446 E01G4.3 Enriched in several structures, including body wall muscle cell from MS lineage; coelomocyte; head mesodermal cell; intestine; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00008447 E01G4.5 Enriched in several structures, including ABalaaaala; ABalaaaarl; body wall muscle cell; ciliated neurons; and germ line based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; allantoin; and antimycin based on RNA-seq and microarray studies. WB:WBGene00008448 E01G4.6 Enriched in PLM; amphid neurons; amphid sheath cell; and rectal epithelial cell based on RNA-seq; single-cell RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; microarray; and RNA-seq studies. Is affected by twenty-eight chemicals including Heme; hydrogen sulfide; and methylmercury hydroxide based on microarray; RNA-seq; and proteomic studies. WB:WBGene00008449 E01G6.1 Predicted to enable chitin binding activity and serine-type endopeptidase inhibitor activity. WB:WBGene00008450 E01G6.2 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppppapa; body wall musculature; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008451 cest-3 Predicted to enable carboxylic ester hydrolase activity. Involved in ascaroside biosynthetic process. Predicted to be located in membrane. WB:WBGene00008452 mrps-5 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS5 (mitochondrial ribosomal protein S5). WB:WBGene00008453 E02A10.3 Predicted to enable calcium ion binding activity and microtubule binding activity. Predicted to be located in microtubule organizing center. Is an ortholog of human CETN1 (centrin 1). WB:WBGene00008454 E02A10.4 Enriched in neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008455 E02H1.1 Predicted to enable rRNA (adenine-N6,N6-)-dimethyltransferase activity. Predicted to be involved in rRNA methylation and ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human DIMT1 (DIM1 rRNA methyltransferase and ribosome maturation factor). WB:WBGene00008456 eral-1 Predicted to enable rRNA binding activity and ribosomal small subunit binding activity. Involved in positive regulation of egg-laying behavior and regulation of aerobic respiration. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in Perrault syndrome 6. Is an ortholog of human ERAL1 (Era like 12S mitochondrial rRNA chaperone 1). WB:WBGene00008457 E02H1.5 Predicted to enable RNA binding activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be part of tRNA-splicing ligase complex. Is an ortholog of human RTRAF (RNA transcription, translation and transport factor). WB:WBGene00008458 E02H1.6 Predicted to enable ATP binding activity and adenylate kinase activity. Predicted to be involved in nucleoside monophosphate phosphorylation and phosphorylation. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human AK6 (adenylate kinase 6). WB:WBGene00008459 mrpl-53 Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL53 (mitochondrial ribosomal protein L53). WB:WBGene00008460 E02H4.2 Enriched in AVK and sensory neurons based on RNA-seq studies. Is affected by several genes including skn-1; eat-2; and pgl-1 based on tiling array and RNA-seq studies. Is affected by nine chemicals including rotenone; multi-walled carbon nanotube; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00008462 E02H4.4 Predicted to be located in extracellular region. WB:WBGene00008463 E02H4.5 Enriched in intestine and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; dpy-21; and ubc-9 based on tiling array; RNA-seq; and microarray studies. Is affected by Tunicamycin and resveratrol based on microarray studies. WB:WBGene00008464 E02H4.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00008465 E03A3.5 Enriched in GABAergic neurons and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-12; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00008468 E03G2.1 Enriched in AFD; ASIL; ASIR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and alg-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Mercuric Chloride and dibromoacetic acid based on microarray studies. WB:WBGene00008469 E03H4.1 No description available WB:WBGene00008470 E03H4.2 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00008471 E03H4.3 Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be located in membrane. WB:WBGene00008472 E03H4.4 Predicted to be located in membrane. WB:WBGene00008473 E03H4.5 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00008474 nhr-174 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008475 oac-13 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00008476 E03H4.8 Predicted to enable structural molecule activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be part of membrane coat. WB:WBGene00008477 clec-17 Enriched in head mesodermal cell; intestine; male-specific anatomical entity; mechanosensory neurons; and pharyngeal muscle cell based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty-six chemicals including Heme; hydrogen sulfide; and methylmercury hydroxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00008478 E03H4.11 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. WB:WBGene00008479 glct-2 Predicted to enable galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity. Predicted to be involved in carbohydrate metabolic process and chondroitin sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in Barrett's esophagus; Larsen-like syndrome B3GAT3 type; and schizophrenia. Is an ortholog of human B3GAT1 (beta-1,3-glucuronyltransferase 1); B3GAT2 (beta-1,3-glucuronyltransferase 2); and B3GAT3 (beta-1,3-glucuronyltransferase 3). WB:WBGene00008480 eif-2A Predicted to enable nucleic acid binding activity and ribosome binding activity. Involved in positive regulation of gene expression. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human EIF2A (eukaryotic translation initiation factor 2A). WB:WBGene00008481 frpr-21 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00008482 cut-4 Predicted to be a structural constituent of cuticle. Predicted to be located in plasma membrane. WB:WBGene00008483 E04D5.4 Enriched in intestine and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-four chemicals including 1-methylnicotinamide; Tunicamycin; and mianserin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00008484 E04D5.5 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00008485 ugt-43 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00008486 ugt-44 Predicted to enable UDP-glycosyltransferase activity. Involved in innate immune response. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1). WB:WBGene00008487 F01D4.3 Enriched in AVK; FLP; germ line; and in male based on microarray and RNA-seq studies. Is affected by several genes including eat-2; clk-1; and npr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; methylmercuric chloride; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00008488 F01D4.5 Predicted to enable metal ion binding activity. Expressed in hypodermis; male gonad; nervous system; and vulva. WB:WBGene00008489 srb-17 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in chemosensory neurons; head muscle; intestine; seam cell; and vulva. WB:WBGene00008490 F01D4.8 Predicted to be involved in cysteine biosynthetic process. Predicted to be located in cytoplasm. WB:WBGene00008491 bgnt-1.1 Predicted to be located in membrane. Expressed in phasmid sheath cell. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A13. Is an ortholog of human B4GAT1 (beta-1,4-glucuronyltransferase 1). WB:WBGene00008492 F01D5.1 Involved in innate immune response. WB:WBGene00008493 F01D5.2 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty chemicals including rotenone; Tunicamycin; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00008494 F01D5.3 Involved in innate immune response. WB:WBGene00008495 F01D5.5 Involved in innate immune response. WB:WBGene00008496 F01D5.6 Predicted to be located in membrane. Predicted to be part of acetylcholine-gated channel complex. WB:WBGene00008497 F01D5.7 Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to be located in endosome membrane and plasma membrane. WB:WBGene00008498 F01D5.8 Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to be located in endosome membrane and plasma membrane. WB:WBGene00008499 cyp-37A1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Is an ortholog of human CYP4V2 (cytochrome P450 family 4 subfamily V member 2). WB:WBGene00008500 F01D5.10 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00008501 fbxa-177 Is affected by rsr-2 based on tiling array studies. Is affected by Progesterone based on microarray studies. WB:WBGene00008502 skih-2 Predicted to enable RNA helicase activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay. Predicted to be part of Ski complex. Human ortholog(s) of this gene implicated in trichohepatoenteric syndrome 2. Is an ortholog of human SKIC2 (SKI2 subunit of superkiller complex). WB:WBGene00008503 F01G4.4 Enriched in several structures, including DB neuron; DD neuron; RIH; germ line; and male distal tip cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including glp-1; daf-12; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by ten chemicals including aldicarb; manganese chloride; and bisphenol S based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008504 pigq-1 Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 4. Is an ortholog of human PIGQ (phosphatidylinositol glycan anchor biosynthesis class Q). WB:WBGene00008505 F01G4.6 Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human SLC25A3 (solute carrier family 25 member 3). WB:WBGene00008506 tkt-1 Predicted to enable thiamine pyrophosphate binding activity and transketolase activity. Predicted to be located in mitochondrion. Is an ortholog of human TKT (transketolase) and TKTL2 (transketolase like 2). WB:WBGene00008507 F01G10.4 Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including indole; Rifampin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00008508 F01G10.5 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00008509 F01G10.6 Enriched in pharyngeal-intestinal valve; rectal gland cell; and touch receptor neurons based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00008510 lipl-7 Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be involved in lipid catabolic process. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). WB:WBGene00008511 F01G10.9 Enriched in several structures, including G2; W cell; hypodermis; interfacial epithelial cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seventeen chemicals including Heme; methylmercury hydroxide; and stavudine based on microarray and RNA-seq studies. WB:WBGene00008512 F01G10.10 Predicted to enable lipid binding activity. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in Crohn's disease and severe acute respiratory syndrome. Is an ortholog of human LBP (lipopolysaccharide binding protein). WB:WBGene00008513 F02A9.1 Predicted to be located in membrane. WB:WBGene00008514 mrpl-44 Predicted to enable ribonuclease III activity. Predicted to be involved in mitochondrial translational elongation. Predicted to be located in nucleus. Predicted to be part of microprocessor complex and mitochondrial large ribosomal subunit. Expressed in metacorpus; pm4; pm7; and terminal bulb. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 16. Is an ortholog of human MRPL44 (mitochondrial ribosomal protein L44). WB:WBGene00008515 F02C12.1 Predicted to enable zinc ion binding activity. Predicted to be located in membrane. WB:WBGene00008516 F02C12.2 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Mercuric Chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. Human HSD17B14 enables estradiol 17-beta-dehydrogenase [NAD(P)] activity; identical protein binding activity; and testosterone 17-beta-dehydrogenase (NADP+) activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; Enoyl-(Acyl carrier protein) reductase; and Phosphorylation site. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00008517 F02C12.3 Enriched in several structures, including germ line; interfacial epithelial cell; neurons; rectum; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00008518 irld-2 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by paraquat based on RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00008519 cyp-13B1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00008520 F02D8.1 Enriched in ADF; ASK; and neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and alg-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008521 F02D8.4 Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. WB:WBGene00008522 nlp-59 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00008523 F02D10.2 Enriched in neurons based on RNA-seq studies. Is affected by rsr-2 and mir-34 based on tiling array and microarray studies. WB:WBGene00008524 F02D10.3 Enriched in body wall muscle cell; neurons; and in male based on tiling array and RNA-seq studies. Is affected by several genes including let-60; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008526 F02D10.6 Predicted to be located in membrane. WB:WBGene00008527 set-8 Predicted to enable double-stranded DNA binding activity and histone methyltransferase activity. Predicted to be involved in chromatin remodeling. WB:WBGene00008528 F02E9.1 Predicted to enable unfolded protein binding activity. Predicted to be involved in vacuolar proton-transporting V-type ATPase complex assembly. Located in endoplasmic reticulum. WB:WBGene00008529 F02E9.3 Enriched in several structures, including ABalaapppp; ABalapaapp; ABalappppa; AVK; and germ line based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including nicotinic acid; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00008530 F02E9.5 Predicted to be involved in cellular response to hydrogen peroxide. Is an ortholog of human OSER1 (oxidative stress responsive serine rich 1). WB:WBGene00008531 F02E9.7 Predicted to enable acid phosphatase activity; ferric iron binding activity; and ferrous iron binding activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia. Is an ortholog of human ACP5 (acid phosphatase 5, tartrate resistant). WB:WBGene00008532 dpt-1 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human DPP3 (dipeptidyl peptidase 3). WB:WBGene00008533 F02E9.10 Predicted to be part of Cdc73/Paf1 complex. Is an ortholog of human SKIC8 (SKI8 subunit of superkiller complex). WB:WBGene00008534 F02H6.1 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00008535 F02H6.2 Enriched in several structures, including AFD; germ line; hypodermis; pharyngeal muscle cell; and rect_D based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including D-glucose; Zidovudine; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008536 F02H6.3 Enriched in NSM; cephalic sheath cell; germ line; hypodermis; and pharyngeal muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; rotenone; and mianserin based on microarray and RNA-seq studies. WB:WBGene00008537 F02H6.4 Enriched in cephalic sheath cell and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; mianserin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00008538 sqrd-1 Predicted to enable FAD binding activity and sulfide:quinone oxidoreductase activity. Predicted to be involved in sulfide oxidation, using sulfide:quinone oxidoreductase. Predicted to be located in mitochondrion. Is an ortholog of human SQOR (sulfide quinone oxidoreductase). WB:WBGene00008539 F02H6.6 Enriched in ABarppaapp; ABarpppapp; NSM; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; nhr-49; and csr-1 based on RNA-seq and microarray studies. Is affected by Alovudine and Sirolimus based on RNA-seq studies. WB:WBGene00008540 F02H6.7 Is affected by hpl-2; csr-1; and rsd-2 based on tiling array and RNA-seq studies. WB:WBGene00008541 spsp-1 Enriched in AVK; MSpaaapa; germ line; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-five chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008542 scav-6 Predicted to enable scavenger receptor activity. Predicted to be involved in endocytosis. Predicted to be located in cytoplasm. Is an ortholog of human SCARB1 (scavenger receptor class B member 1). WB:WBGene00008543 F07A5.4 Predicted to be involved in signal transduction. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in juvenile glaucoma; low tension glaucoma; and ocular hypertension. Is an ortholog of several human genes including MYOC (myocilin); OLFM1 (olfactomedin 1); and OLFML2B (olfactomedin like 2B). WB:WBGene00008545 F07A11.1 Enriched in BAG and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; pie-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including allantoin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008546 gfat-1 Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Involved in IRE1-mediated unfolded protein response. Expressed in tail. Used to study Machado-Joseph disease. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12; obesity; and type 2 diabetes mellitus. Is an ortholog of human GFPT1 (glutamine--fructose-6-phosphate transaminase 1). WB:WBGene00008547 F07A11.4 Predicted to enable cysteine-type deubiquitinase activity and metal ion binding activity. Predicted to be involved in proteolysis. Is an ortholog of human USP19 (ubiquitin specific peptidase 19). WB:WBGene00008548 F07A11.5 Predicted to enable ATP binding activity; metal ion binding activity; and ribokinase activity. Predicted to be involved in D-ribose catabolic process and carbohydrate phosphorylation. Predicted to be located in cytosol. Is an ortholog of human RBKS (ribokinase). WB:WBGene00008549 din-1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Located in nucleus. Expressed in several structures, including body wall musculature; hermaphrodite distal tip cell; intestine; pharynx; and vulval precursor cell. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma and nasopharynx carcinoma. Is an ortholog of human SPEN (spen family transcriptional repressor). WB:WBGene00008550 F07B10.4 Predicted to be located in membrane. WB:WBGene00008551 lgc-36 Predicted to enable neurotransmitter receptor activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; autistic disorder; and epilepsy (multiple). Is an ortholog of several human genes including GABRA1 (gamma-aminobutyric acid type A receptor subunit alpha1); GABRA2 (gamma-aminobutyric acid type A receptor subunit alpha2); and GABRA3 (gamma-aminobutyric acid type A receptor subunit alpha3). WB:WBGene00008552 srsx-31 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of several human genes including OR2M4 (olfactory receptor family 2 subfamily M member 4); OR5H1 (olfactory receptor family 5 subfamily H member 1); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00008553 F07C6.2 Predicted to be located in membrane. WB:WBGene00008554 F07C6.3 Enriched in AFD; AMshL; AMshR; amphid sheath cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; bisphenol A; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00008555 F07C6.4 Predicted to be involved in establishment of epithelial cell polarity. Predicted to be located in cytoplasm. Is an ortholog of human FRMD4A (FERM domain containing 4A) and FRMD4B (FERM domain containing 4B). WB:WBGene00008556 F07D3.3 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to be located in cytosol. WB:WBGene00008557 idpa-2 Enriched in several structures, including GABAergic neurons; GLR; arcade cell; coelomocyte; and head mesodermal cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00008558 F07H5.7 Predicted to be located in membrane. WB:WBGene00008559 appg-2 Enriched in ABplppppaa; ABprppppaa; head mesodermal cell; neurons; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty chemicals including methylmercury hydroxide; rotenone; and sodium arsenite based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Cysteine rich repeat, tripleX and Cysteine rich repeat. WB:WBGene00008560 pho-13 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00008561 F07H5.10 Predicted to enable mRNA 5'-diphosphatase activity. Predicted to be involved in NAD-cap decapping; nuclear-transcribed mRNA catabolic process; and nucleic acid phosphodiester bond hydrolysis. Predicted to be located in cytosol and nucleus. WB:WBGene00008563 F07H5.13 Enriched in AVK; body wall muscle cell; intestine; pharyngeal cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including methylmercury hydroxide; 1-methylnicotinamide; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00008564 acox-1.1 Enables ATP binding activity and acyl-CoA oxidase activity. Involved in ascaroside biosynthetic process; fatty acid beta-oxidation using acyl-CoA oxidase; and pheromone biosynthetic process. Located in peroxisomal matrix. Expressed in hypodermis; intestinal cell; and intestine. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 6 and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1). WB:WBGene00008565 acox-1.2 Enables ATP binding activity and acyl-CoA oxidase activity. Involved in ascaroside biosynthetic process and fatty acid beta-oxidation using acyl-CoA oxidase. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 6 and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1). WB:WBGene00008566 acox-1.3 Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in ascaroside biosynthetic process and pheromone biosynthetic process. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 6 and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1). WB:WBGene00008567 acox-1.4 Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Involved in ascaroside biosynthetic process and pheromone biosynthetic process. Predicted to be located in peroxisome. Expressed in intestine. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 6 and peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1). WB:WBGene00008568 F08A8.5 Predicted to enable glycosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in Golgi cisterna membrane. WB:WBGene00008569 fbxa-101 Enriched in germ line and germline precursor cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including manganese chloride; bisphenol S; and Zidovudine based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00008570 kcnl-2 Predicted to enable calmodulin binding activity and small conductance calcium-activated potassium channel activity. Involved in positive regulation of egg-laying behavior. Located in neuron projection. Expressed in nervous system; seam cell; and vulval muscle. Human ortholog(s) of this gene implicated in dystonia and paranoid schizophrenia. Is an ortholog of human KCNN1 (potassium calcium-activated channel subfamily N member 1). WB:WBGene00008571 prmn-1 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in cone-rod dystrophy 12; retinal macular dystrophy; and retinitis pigmentosa 41. Is an ortholog of human PROM1 (prominin 1) and PROM2 (prominin 2). WB:WBGene00008572 F08B12.4 Located in nucleus. Expressed in body wall musculature; metacorpus; and tail. WB:WBGene00008574 srbc-61 Predicted to be located in membrane. WB:WBGene00008575 scl-24 Predicted to be located in extracellular space. WB:WBGene00008576 F08G2.4 Enriched in several structures, including ABalapapapa; ABalapppapa; ABplpaaappa; ABprpaaappa; and PVW based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; Alovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00008577 F08G2.5 Involved in innate immune response. WB:WBGene00008578 F08G2.7 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalpapaap; ABarappaap; and muscle cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Zidovudine; Tunicamycin; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008579 F08G2.8 Enriched in ABplapaaap; ABprapaaap; amphid sensillum; body wall muscle cell from C lineage; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including D-glucose; Zidovudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00008580 dsb-1 Located in condensed chromosome. Expressed in gonad. WB:WBGene00008581 acl-13 Predicted to enable acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Predicted to be located in endoplasmic reticulum. WB:WBGene00008582 F08G5.3 Enriched in head mesodermal cell; muscle cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by metformin; Sirolimus; and resveratrol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008583 ugt-65 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00008584 irg-4 Involved in defense response to Gram-negative bacterium and innate immune response. Expressed in head neurons and intestine. WB:WBGene00008585 F08G12.1 Predicted to enable GTP binding activity. Predicted to be located in cytosol and nucleus. Expressed in head muscle; hermaphrodite distal tip cell; neurons; and pharyngeal muscle cell. Is an ortholog of human RABL6 (RAB, member RAS oncogene family like 6). WB:WBGene00008586 snrp-40.1 Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human SNRNP40 (small nuclear ribonucleoprotein U5 subunit 40). WB:WBGene00008587 F08G12.3 Enriched in several structures, including ABaraapapaa; ABaraapppaa; coelomocyte; head mesodermal cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00008588 F08G12.5 Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm and membrane. WB:WBGene00008589 nlp-57 Predicted to be involved in neuropeptide signaling pathway. Expressed in intestine and nervous system. WB:WBGene00008590 F08H9.2 Predicted to enable DNA binding activity. WB:WBGene00008591 F08H9.3 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in intestinal cell and pharynx. WB:WBGene00008592 F08H9.4 Predicted to enable unfolded protein binding activity. Involved in response to topologically incorrect protein. Predicted to be located in cytoplasm and nucleus. Expressed in excretory canal; head neurons; and ventral cord neurons. WB:WBGene00008593 clec-227 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-nine chemicals including Heme; aldicarb; and hydrogen sulfide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00008594 clec-57 Enriched in hyp3; intestine; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-six chemicals including tryptophan; D-glucopyranose; and D-glucose based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00008595 clec-56 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including Mercuric Chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00008596 clec-54 Enriched in anterior arcade cell and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; rotenone; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00008597 clec-55 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including aldicarb; methylmercuric chloride; and Mercuric Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00008598 spin-3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in amphid neurons; intestine; and retrovesicular ganglion neurons. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 115. Is an ortholog of human SPNS1 (SPNS lysolipid transporter 1, lysophospholipid); SPNS2 (SPNS lysolipid transporter 2, sphingosine-1-phosphate); and SPNS3 (SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)). WB:WBGene00008599 F09A5.2 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. WB:WBGene00008600 F09A5.3 Enriched in anterior hypodermis; arc ant V; excretory gland cell; intestine; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including let-60; daf-12; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00008601 mob-2 Predicted to enable protein kinase activator activity. Predicted to be involved in positive regulation of protein phosphorylation and signal transduction. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human MOB2 (MOB kinase activator 2). WB:WBGene00008602 oac-14 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00008603 F09B9.4 Expressed in body wall musculature. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008604 F09B9.5 Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in pancreatic ductal adenocarcinoma. Is an ortholog of human GLIPR2 (GLI pathogenesis related 2). WB:WBGene00008605 mlt-9 Expressed in hypodermis. Is predicted to encode a protein with the following domain: Concanavalin A-like lectin/glucanase domain superfamily. WB:WBGene00008606 dhhc-1 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Is an ortholog of human ZDHHC24 (zinc finger DHHC-type containing 24). WB:WBGene00008607 F09B12.3 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid catabolic process. Predicted to be located in extracellular region. Is an ortholog of human PLBD2 (phospholipase B domain containing 2). WB:WBGene00008609 F09B12.5 Predicted to be located in plasma membrane. WB:WBGene00008610 nanp-1 Predicted to enable phosphoglycolate phosphatase activity. Predicted to be involved in DNA repair and dephosphorylation. Expressed in hypodermis; intestine; and motor neurons. WB:WBGene00008611 fbxb-68 Enriched in arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00008612 fbxa-103 Enriched in several structures, including ABalppappa; ABalppppaa; ABalpppppa; CAN; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Alovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00008613 fbxb-69 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapapapa; ABalapappaa; and ciliated neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00008614 F09C3.6 No description available WB:WBGene00008615 ifas-2 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament polymerization. Predicted to be located in actin cytoskeleton. WB:WBGene00008616 fbxa-44 Enriched in pharyngeal muscle cell based on tiling array studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq; tiling array; and microarray studies. Is affected by nine chemicals including methylmercuric chloride; multi-walled carbon nanotube; and tert-Butylhydroperoxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00008617 F09C6.3 Enriched in ASER and Caapa based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and sek-1 based on RNA-seq; tiling array; and microarray studies. Is affected by seventeen chemicals including methylmercuric chloride; sodium arsenite; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008618 fbxa-45 Is affected by several genes including clk-1; cyc-1; and ahr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00008619 nhr-262 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008620 F09C6.10 Enriched in RIBL; RIBR; male-specific anatomical entity; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Sodium Chloride; metformin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00008621 F09C8.1 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Expressed in intestine. Is an ortholog of human PLB1 (phospholipase B1). WB:WBGene00008622 F09C8.2 Enriched in several structures, including ABplaapaap; ABplpaapap; ABpraapaap; AVK; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including aldicarb; 1-methylnicotinamide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Coiled-coil domain-containing protein R3HC1/R3HCL and Phosphorylation site. Is an ortholog of human R3HCC1 (R3H domain and coiled-coil containing 1) and R3HCC1L (R3H domain and coiled-coil containing 1 like). WB:WBGene00008623 spe-43 Predicted to be located in membrane. WB:WBGene00008624 crld-1 Predicted to enable calcium ion binding activity and protein disulfide isomerase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum lumen and endoplasmic reticulum membrane. Expressed in several structures, including body wall musculature; gonad; hypodermis; intestine; and pharynx. Human ortholog(s) of this gene implicated in atrioventricular septal defect. Is an ortholog of human CRELD1 (cysteine rich with EGF like domains 1) and CRELD2 (cysteine rich with EGF like domains 2). WB:WBGene00008625 scl-14 Predicted to be located in extracellular space. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00008626 nlp-79 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00008627 hpx-2 Predicted to enable peroxidase activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in extracellular region. Expressed in gland cell and hypodermis. WB:WBGene00008628 ttr-21 Involved in defense response to Gram-negative bacterium. Predicted to be located in cell surface and extracellular region. WB:WBGene00008629 cpt-5 Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in carnitine metabolic process and fatty acid metabolic process. Predicted to be located in mitochondrion. WB:WBGene00008630 nhr-175 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008631 F10A3.1 Predicted to be located in membrane. WB:WBGene00008632 fbxa-88 Is affected by several genes including daf-2; glp-1; and age-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Heme; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00008633 fbxa-18 Enriched in intestine based on tiling array studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Mercuric Chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily and F-box domain. WB:WBGene00008634 F10A3.4 Predicted to be involved in innate immune response. Expressed in intestine and tail neurons. WB:WBGene00008635 F10A3.7 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by copper sulfate based on microarray studies. WB:WBGene00008636 F10A3.11 Enriched in germ line; muscle cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and csr-1 based on microarray and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; resveratrol; and Chlorpyrifos based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00008637 F10A3.12 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00008638 F10A3.16 Is affected by csr-1 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00008639 F10B5.2 Predicted to be involved in spliceosomal tri-snRNP complex assembly. Is an ortholog of human AAR2 (AAR2 splicing factor). WB:WBGene00008640 F10B5.3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00008641 pch-2 Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in meiotic recombination checkpoint signaling and reciprocal meiotic recombination. Located in kinetochore. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome 3. Is an ortholog of human TRIP13 (thyroid hormone receptor interactor 13). WB:WBGene00008642 ints-11 Predicted to enable RNA endonuclease activity. Predicted to be involved in snRNA processing. Predicted to be located in nucleus. Is an ortholog of human INTS11 (integrator complex subunit 11). WB:WBGene00008643 tmem-138 Located in ciliary transition zone. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in Joubert syndrome 16. Is an ortholog of human TMEM138 (transmembrane protein 138). WB:WBGene00008644 F10C2.3 Enriched in intestine; neurons; and rectal gland cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and lin-39 based on RNA-seq and microarray studies. Is affected by seventeen chemicals including Tunicamycin; 4-bromodiphenyl ether; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Alkaline-phosphatase-like, core domain superfamily; Protein of unknown function (DUF229); and Protein of unknown function DUF229. WB:WBGene00008645 F10C2.4 Predicted to enable 3'-5'-DNA exonuclease activity and DNA-directed DNA polymerase activity. Predicted to be involved in DNA replication proofreading; base-excision repair, gap-filling; and nucleotide-excision repair, DNA gap filling. Predicted to be located in nucleus. Predicted to be part of delta DNA polymerase complex. Is an ortholog of human POLD1 (DNA polymerase delta 1, catalytic subunit). WB:WBGene00008646 F10C2.5 Predicted to enable calcium ion binding activity and mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in endoplasmic reticulum. Expressed in several structures, including body wall musculature; intestine; neurons; pharyngeal cell; and vulval muscle. Is an ortholog of human EDEM2 (ER degradation enhancing alpha-mannosidase like protein 2). WB:WBGene00008647 F10C2.7 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in intestine. WB:WBGene00008648 F10D11.2 Enriched in several structures, including ABalpppapa; ABplpaaaaa; ABpraaaapa; ABprpaaaaa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including manganese chloride; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00008649 F10D11.3 Enriched in RIS; germ line; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including manganese chloride; D-glucose; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00008650 F10D11.4 Enriched in NSM; germ line; and in male based on RNA-seq and tiling array studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including methylmercuric chloride; D-glucose; and allantoin based on microarray and RNA-seq studies. WB:WBGene00008651 F10D11.5 Enriched in ASEL; ASER; NSM; germ line; and in male based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including nicotinic acid; manganese chloride; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterized protein T15H9.4-like and PDZ superfamily. WB:WBGene00008652 F10D11.6 Predicted to enable lipid binding activity. Predicted to be located in extracellular space. Is an ortholog of human BPIFC (BPI fold containing family C) and LBP (lipopolysaccharide binding protein). WB:WBGene00008654 pfas-1 Predicted to enable phosphoribosylformylglycinamidine synthase activity. Predicted to be involved in purine nucleotide biosynthetic process. Predicted to be located in cytoplasm. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in colon adenocarcinoma; hepatocellular carcinoma; and renal cell carcinoma. Is an ortholog of human PFAS (phosphoribosylformylglycinamidine synthase). WB:WBGene00008655 lips-3 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00008656 lron-5 Predicted to be located in membrane. Expressed in nerve ring; tail; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); corneal disease (multiple); and periodontal disease (multiple). Is an ortholog of several human genes including FMOD (fibromodulin); LUM (lumican); and OMD (osteomodulin). WB:WBGene00008657 clec-154 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00008658 clec-152 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00008659 clec-151 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by fifteen chemicals including hydrogen sulfide; methylmercuric chloride; and allantoin based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00008660 clec-153 Enriched in OLLL; OLLR; amphid sheath cell; intestine; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including Ethanol; methylmercuric chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00008661 F10G8.1 Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of human PTPN7 (protein tyrosine phosphatase non-receptor type 7). WB:WBGene00008662 F10G8.2 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00008663 eak-6 Predicted to enable protein tyrosine phosphatase activity. Involved in dauer larval development. Located in plasma membrane. Expressed in XXXL and XXXR. WB:WBGene00008664 nubp-1 Predicted to enable iron-sulfur cluster binding activity. Involved in regulation of non-motile cilium assembly. Predicted to be located in cytosol. Expressed in amphid neurons; inner labial neurons; outer labial neurons; and phasmid neurons. Is an ortholog of human NUBP1 (NUBP iron-sulfur cluster assembly factor 1, cytosolic). WB:WBGene00008665 ercc-1 Enables enzyme binding activity and identical protein binding activity. Involved in UV-damage excision repair and base-excision repair. Predicted to be located in nucleus. Predicted to be part of ERCC4-ERCC1 complex and nucleotide-excision repair factor 1 complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Is an ortholog of human ERCC1 (ERCC excision repair 1, endonuclease non-catalytic subunit). WB:WBGene00008666 F10G8.8 Predicted to enable actin filament binding activity. Predicted to be located in actin cytoskeleton. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 28. Is an ortholog of human MPRIP (myosin phosphatase Rho interacting protein). WB:WBGene00008667 F10G8.9 Predicted to enable 3-oxoacyl-[acyl-carrier-protein] synthase activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to be located in mitochondrion. Is an ortholog of human OXSM (3-oxoacyl-ACP synthase, mitochondrial). WB:WBGene00008669 acs-14 Predicted to enable CoA-ligase activity. WB:WBGene00008670 eif-2Bdelta Predicted to enable translation initiation factor activity. Involved in several processes, including determination of adult lifespan; lipid storage; and response to heat. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter 4. Is an ortholog of human EIF2B4 (eukaryotic translation initiation factor 2B subunit delta). WB:WBGene00008671 rabr-4 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in Golgi membrane. WB:WBGene00008672 rabr-3 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in Golgi membrane. WB:WBGene00008673 F11A5.5 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00008675 irld-26 Is affected by several genes including lin-4; lin-14; and sir-2.1 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00008676 oac-15 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00008677 F11A5.9 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00008678 stdh-2 Predicted to enable oxidoreductase activity. Predicted to be involved in fatty acid elongation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). WB:WBGene00008679 F11A5.13 Predicted to be located in membrane. WB:WBGene00008680 F11A5.15 Predicted to be located in membrane. WB:WBGene00008681 scrm-4 Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be located in plasma membrane. Is an ortholog of several human genes including PLSCR2 (phospholipid scramblase 2); PLSCR3 (phospholipid scramblase 3); and PLSCR4 (phospholipid scramblase 4). WB:WBGene00008682 lex-1 Predicted to enable ATP hydrolysis activity; chromatin binding activity; and histone binding activity. Involved in regulation of heterochromatin formation. Predicted to be located in nucleus. Is an ortholog of human ATAD2 (ATPase family AAA domain containing 2) and ATAD2B (ATPase family AAA domain containing 2B). WB:WBGene00008683 repo-1 Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in spliceosomal complex assembly. Predicted to be located in nucleus. Predicted to be part of U2 snRNP; U2-type prespliceosome; and catalytic step 2 spliceosome. Expressed in head. Is an ortholog of human SF3A2 (splicing factor 3a subunit 2). WB:WBGene00008684 mig-32 Enables histone ubiquitin ligase activity. Involved in several processes, including negative regulation of vulval development; nematode male tail tip morphogenesis; and regulation of axon extension involved in axon guidance. Located in nucleolus. Expressed in several structures, including germ line and ventral ganglion. Is an ortholog of human PCGF3 (polycomb group ring finger 3). WB:WBGene00008685 mon-2 Predicted to be involved in protein transport. Predicted to be located in Golgi apparatus. Expressed in several structures, including intestine; neurons; and seam cell. Is an ortholog of human MON2 (MON2 homolog, regulator of endosome-to-Golgi trafficking). WB:WBGene00008686 F11A10.5 Predicted to be located in membrane. Is an ortholog of human ST7 (suppression of tumorigenicity 7). WB:WBGene00008687 F11A10.6 Predicted to be involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in Golgi apparatus. Is an ortholog of human TMEM115 (transmembrane protein 115). WB:WBGene00008688 rbm-34 Predicted to enable rRNA binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Is an ortholog of human RBM34 (RNA binding motif protein 34). WB:WBGene00008690 F11C1.1 Predicted to enable protein-disulfide reductase activity. Predicted to be involved in protein import into mitochondrial intermembrane space and protein maturation by protein folding. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human CHCHD4 (coiled-coil-helix-coiled-coil-helix domain containing 4). WB:WBGene00008691 mff-1 Predicted to be involved in mitochondrial fission; positive regulation of mitochondrial fission; and positive regulation of protein targeting to membrane. Predicted to be located in mitochondrial outer membrane and peroxisome. WB:WBGene00008692 scav-4 Predicted to enable scavenger receptor activity. Predicted to be involved in endocytosis. Predicted to be located in cytoplasm. Is an ortholog of human SCARB1 (scavenger receptor class B member 1). WB:WBGene00008693 F11C1.4 Predicted to enable lipase activity. Predicted to be involved in lipid storage. Predicted to be located in lipid droplet. Is an ortholog of human LDAH (lipid droplet associated hydrolase). WB:WBGene00008694 vwa-8 Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be located in cytoplasm. Expressed in hypodermal cell; intestinal cell; and muscle cell. Is an ortholog of human VWA8 (von Willebrand factor A domain containing 8). WB:WBGene00008695 F11C3.1 Predicted to enable 5'-3' DNA helicase activity. Predicted to be involved in DNA duplex unwinding and DNA replication. Predicted to be located in replication fork. WB:WBGene00008696 clec-255 Enriched in CEM; HOB; IL2 neuron; and ray neuron type B based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Alovudine; dafa#1; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; C-type lectin fold; and PAN-3 domain. WB:WBGene00008697 F11D11.2 No description available WB:WBGene00008698 F11D11.3 Involved in innate immune response. WB:WBGene00008699 F11D11.4 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on RNA-seq; proteomic; and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008700 clec-254 Is affected by several genes including aak-2; set-2; and drh-3 based on RNA-seq studies. Is affected by dafa#1 based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; C-type lectin fold; and PAN-3 domain. WB:WBGene00008701 F11D11.6 Is affected by several genes including clk-1; aak-2; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00008702 clec-252 Is affected by several genes including eat-2; clk-1; and isp-1 based on microarray; tiling array; and RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like/link domain superfamily; C-type lectin fold; Phosphorylation site; and PAN-3 domain. WB:WBGene00008703 clec-251 Enriched in AFD and sensory neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; aak-2; and isp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by cadmium based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; and PAN-3 domain. WB:WBGene00008704 F11D11.9 No description available WB:WBGene00008706 gba-3 Predicted to enable glucosylceramidase activity. Predicted to be involved in glucosylceramide catabolic process. Human ortholog(s) of this gene implicated in several diseases, including Gaucher's disease (multiple); Lewy body dementia; and Netherton syndrome. Is an ortholog of human GBA1 (glucosylceramidase beta 1). WB:WBGene00008707 epic-1 Enriched in several structures, including accessory cell; anterior hypodermis; germ line; rectal epithelial cell; and rectum based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including diallyl trisulfide; nicotinic acid; and rotenone based on microarray and RNA-seq studies. WB:WBGene00008708 F11E6.4 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and Caappd based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008709 F11E6.6 Predicted to be located in membrane. WB:WBGene00008710 rif-1.1 Predicted to be involved in telomere maintenance. Predicted to be located in nucleus. Is an ortholog of human RIF1 (replication timing regulatory factor 1). WB:WBGene00008711 F11E6.8 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in cell migration; nervous system development; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in several diseases, including autistic disorder; autosomal recessive nonsyndromic deafness 97; and carcinoma (multiple). Is an ortholog of human MET (MET proto-oncogene, receptor tyrosine kinase) and MST1R (macrophage stimulating 1 receptor). WB:WBGene00008712 F11E6.9 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and ABarpppapa based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including Tunicamycin; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00008713 F11E6.10 Predicted to be located in membrane. WB:WBGene00008714 F11F1.1 Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Predicted to be involved in chaperone cofactor-dependent protein refolding and protein refolding. Predicted to be located in cytoplasm. WB:WBGene00008716 srlf-9 Enriched in DA neuron; dopaminergic neurons; and lateral ganglion based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including metformin; Sirolimus; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00008717 srlf-10 Enriched in several structures, including DA neuron; VA neuron; cephalic sheath cell; germ line; and lateral ganglion based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including clk-1; set-2; and mir-34 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00008719 ttr-52 Enables several functions, including phosphatidylserine binding activity; protein homodimerization activity; and scavenger receptor binding activity. Involved in aminophospholipid transport; apoptotic process involved in development; and recognition of apoptotic cell. Located in cell surface and extracellular vesicle. WB:WBGene00008720 F12F6.1 Predicted to be located in cytoplasm. WB:WBGene00008722 F12F6.7 Predicted to enable DNA binding activity and DNA-directed DNA polymerase activity. Predicted to be involved in DNA strand elongation involved in DNA replication. Predicted to be located in nucleus. Predicted to be part of delta DNA polymerase complex. Is an ortholog of human POLD2 (DNA polymerase delta 2, accessory subunit). WB:WBGene00008723 F12F6.8 Enriched in germ line based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and alg-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00008724 F13A7.1 Predicted to be located in cytoskeleton. WB:WBGene00008725 F13A7.7 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; let-60; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including hydrogen sulfide; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Papain-like cysteine peptidase superfamily. WB:WBGene00008726 F13A7.11 Predicted to enable hydrolase activity. Involved in innate immune response. WB:WBGene00008727 F13A7.12 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00008728 sre-36 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00008729 F13B12.1 Predicted to be involved in poly(A)+ mRNA export from nucleus. Located in nucleus. Expressed in anal depressor muscle; head neurons; pharyngeal-intestinal valve; and tail. Is an ortholog of human IWS1 (interacts with SUPT6H, CTD assembly factor 1). WB:WBGene00008730 F13B12.2 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC2A11 (solute carrier family 2 member 11); SLC2A7 (solute carrier family 2 member 7); and SLC2A9 (solute carrier family 2 member 9). WB:WBGene00008731 F13B12.3 Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in membrane. WB:WBGene00008732 F13B12.4 Predicted to be involved in cysteine biosynthetic process. Predicted to be located in cytoplasm. WB:WBGene00008733 F13B12.6 Predicted to be located in cytoplasm. Is an ortholog of human SH2D4A (SH2 domain containing 4A). WB:WBGene00008734 F13B12.7 Predicted to be located in membrane. WB:WBGene00008735 F13D2.1 Predicted to enable endopeptidase inhibitor activity. WB:WBGene00008736 gnrr-6 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in ganglia and sensory neurons. WB:WBGene00008737 gnrr-7 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00008739 F13D12.3 Expressed in head and rectal epithelium. WB:WBGene00008740 F13D12.5 Predicted to be located in membrane. WB:WBGene00008741 ctsa-1.2 Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Expressed in intestine. Human ortholog(s) of this gene implicated in galactosialidosis. Is an ortholog of human CTSA (cathepsin A). WB:WBGene00008742 F13D12.8 Predicted to be located in membrane. WB:WBGene00008743 fcmt-1 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in lipid biosynthetic process. WB:WBGene00008744 F13D12.10 Predicted to be located in membrane. WB:WBGene00008745 F13E6.1 Predicted to be located in cytoplasm. Expressed in head and tail. Is an ortholog of human TPD52 (tumor protein D52) and TPD52L1 (TPD52 like 1). WB:WBGene00008746 F13E6.2 Predicted to enable UMP kinase activity and cytidylate kinase activity. Predicted to be involved in CDP biosynthetic process and UDP biosynthetic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human AK5 (adenylate kinase 5). WB:WBGene00008747 phf-31 Predicted to enable metal ion binding activity. WB:WBGene00008748 yap-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in establishment of cell polarity and positive regulation of transcription by RNA polymerase II. Located in axoneme; ciliary base; and nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including excretory system; hermaphrodite gonad; pharyngeal muscle cell; tail hypodermis; and vulva. Human ortholog(s) of this gene implicated in colorectal cancer and uveal coloboma-cleft lip and palate-intellectual disability. Is an ortholog of human WWTR1 (WW domain containing transcription regulator 1) and YAP1 (Yes1 associated transcriptional regulator). WB:WBGene00008749 plpp-1.3 Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. WB:WBGene00008750 nish-1 Predicted to enable alpha-tubulin binding activity and dynein heavy chain binding activity. Predicted to be involved in outer dynein arm assembly. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in congestive heart failure. Is an ortholog of human NISCH (nischarin). WB:WBGene00008751 fipr-14 Enriched in coelomocyte based on tiling array studies. Is affected by several genes including rrf-3; sir-2.1; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Sirolimus based on microarray studies. Is predicted to encode a protein with the following domain: Fungus-induced protein. WB:WBGene00008752 fipr-15 Involved in response to hypoxia. WB:WBGene00008753 srlf-13 Enriched in ABalpapaap; ABarappaap; germ line; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by nfki-1 based on RNA-seq studies. Is affected by five chemicals including procyanidin; Sodium Chloride; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00008754 F13E9.5 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00008755 sdz-13 Enriched in ABplpaaaap and ABprpaaaap based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Tunicamycin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00008756 F13E9.7 No description available WB:WBGene00008757 srlf-14 Enriched in ADL; AFD; amphid sheath cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by methylmercuric chloride and procyanidin based on microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00008758 F13E9.9 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00008759 srlf-11 Enriched in germ line and in male based on proteomic and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array and RNA-seq studies. Is affected by eight chemicals including tryptophan; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00008760 F13E9.11 Predicted to be located in membrane. Is an ortholog of human TMEM121B (transmembrane protein 121B). WB:WBGene00008761 F13E9.12 Enriched in neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including skn-1; elt-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; D-glucose; and allantoin based on RNA-seq studies. WB:WBGene00008762 ztf-2 Enables DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and pharynx morphogenesis. Expressed in pharyngeal neurons; pharynx; rectum; and vulva. WB:WBGene00008763 F13G3.3 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00008764 dylt-1 Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be located in cytoplasm. Predicted to be part of cytoplasmic dynein complex. Expressed in ADFL and ADFR. Is an ortholog of human DYNLT1 (dynein light chain Tctex-type 1) and DYNLT3 (dynein light chain Tctex-type 3). WB:WBGene00008765 ttx-7 Predicted to enable inositol monophosphate 1-phosphatase activity and metal ion binding activity. Involved in chemotaxis; protein localization to synapse; and thermotaxis. Located in cytoplasm. Expressed in several structures, including coelomocyte; gonad; intestine; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 59; bipolar disorder; and schizophrenia. Is an ortholog of human IMPA1 (inositol monophosphatase 1) and IMPA2 (inositol monophosphatase 2). WB:WBGene00008766 F13G3.6 Enriched in ABalaaaala; ABalaapaaa; germ line; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including glp-1; hsf-1; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Glycosyltransferase 2-like; Nucleotide-diphospho-sugar transferases; and Glycosyl transferase family 2. Is an ortholog of human B3GNTL1 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1). WB:WBGene00008767 F13G3.7 Predicted to enable branched-chain amino acid transmembrane transporter activity. Predicted to be involved in branched-chain amino acid transport. Predicted to be located in mitochondrion. Is an ortholog of human SLC25A44 (solute carrier family 25 member 44). WB:WBGene00008768 F13G3.10 Predicted to be involved in negative regulation of apoptotic process and protein stabilization. Is an ortholog of human HYPK (huntingtin interacting protein K). WB:WBGene00008769 mrpl-13 Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in negative regulation of translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL13 (mitochondrial ribosomal protein L13). WB:WBGene00008770 F13G3.12 Enriched in GABAergic neurons and body wall muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; aak-2; and mex-3 based on RNA-seq and microarray studies. Is affected by nine chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008772 irld-4 Predicted to be located in membrane. WB:WBGene00008773 F13H10.1 Enriched in GABAergic neurons; PLM; anterior hypodermis; pharyngeal neurons; and pharyngeal-intestinal valve based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008774 F13H10.3 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in late endosome membrane and lysosomal membrane. Is an ortholog of human SLC38A9 (solute carrier family 38 member 9). WB:WBGene00008775 mogs-1 Predicted to enable Glc3Man9GlcNAc2 oligosaccharide glucosidase activity. Predicted to be involved in oligosaccharide metabolic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIb. Is an ortholog of human MOGS (mannosyl-oligosaccharide glucosidase). WB:WBGene00008776 F13H10.5 Predicted to be located in I band and striated muscle dense body. Is an ortholog of human ENPP6 (ectonucleotide pyrophosphatase/phosphodiesterase 6). WB:WBGene00008777 F13H10.6 Enriched in several structures, including amphid sensillum; anterior ganglion; arcade cell; excretory system; and pharyngeal cell based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; Cry5B; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00008778 nhr-264 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008779 F14B4.1 Predicted to enable calcium ion binding activity. Predicted to be involved in endocytosis. Predicted to be located in membrane. WB:WBGene00008780 hxk-1 Predicted to enable fructokinase activity and glucokinase activity. Predicted to be involved in carbohydrate metabolic process; glucose 6-phosphate metabolic process; and intracellular glucose homeostasis. Predicted to be located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of human GCK (glucokinase). WB:WBGene00008781 rpoa-2 Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and ribonucleoside binding activity. Predicted to contribute to RNA polymerase I activity. Predicted to be involved in transcription by RNA polymerase I. Located in nucleolus. Expressed in several structures, including intestine. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Is an ortholog of human POLR1B (RNA polymerase I subunit B). WB:WBGene00008782 sdz-14 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalaapppa; ABalapaapa; and ciliated neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Mercuric Chloride; rotenone; and stavudine based on microarray and RNA-seq studies. WB:WBGene00008783 F14B6.2 Located in plasma membrane. WB:WBGene00008784 F14B6.3 Enriched in several structures, including ABalppppaa; ABplaapaap; ABpraaapaa; ABpraapaap; and amphid neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; rotenone; and mianserin based on microarray and RNA-seq studies. WB:WBGene00008785 F14B6.4 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. WB:WBGene00008786 oac-16 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00008787 F14B6.6 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. WB:WBGene00008788 F14D7.1 Enriched in FLP; germ line; intestine; and in male based on microarray and RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Tunicamycin; and Doxycycline based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1265; SKP1/BTB/POZ domain superfamily; and Protein of unknown function (DUF1265). WB:WBGene00008789 F14D7.2 Expressed in germ line. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008790 F14D7.3 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; drh-3; and adr-1 based on RNA-seq and microarray studies. WB:WBGene00008791 F14D7.4 Enriched in ALN and HSN based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008792 spig-3 Enriched in amphid sheath cell; arcade cell; and dopaminergic neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; metformin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00008793 F14D7.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00008794 spig-4 Enriched in AMshL; AMshR; amphid sheath cell; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00008795 F14D7.8 Predicted to be located in membrane. WB:WBGene00008796 F14D7.9 Predicted to be located in membrane. WB:WBGene00008797 spig-5 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq; microarray; and proteomic studies. Is affected by nine chemicals including Tunicamycin; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00008798 ddn-3 Predicted to be located in plasma membrane. WB:WBGene00008799 fdgt-2 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00008800 F14E5.2 Predicted to enable fibroblast growth factor binding activity. Predicted to be located in Golgi membrane. Is an ortholog of human GLG1 (golgi glycoprotein 1). WB:WBGene00008801 acp-3 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in membrane. Is an ortholog of human ACP6 (acid phosphatase 6, lysophosphatidic). WB:WBGene00008802 acp-2 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Expressed in ALML; ALMR; PLML; PLMR; and spermatheca. Is an ortholog of human ACP6 (acid phosphatase 6, lysophosphatidic). WB:WBGene00008803 lips-10 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00008804 acp-4 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in membrane. Is an ortholog of human ACP6 (acid phosphatase 6, lysophosphatidic). WB:WBGene00008805 git-1 Predicted to enable GTPase activator activity and small GTPase binding activity. Involved in gonad morphogenesis and inductive cell migration. Located in hemidesmosome and presynaptic active zone. Human ortholog(s) of this gene implicated in Huntington's disease and attention deficit hyperactivity disorder. Is an ortholog of human GIT2 (GIT ArfGAP 2). WB:WBGene00008806 mboa-7 Enables O-acyltransferase activity. Involved in egg-laying behavior; nematode larval development; and phosphatidylinositol biosynthetic process. Located in intracellular membrane-bounded organelle. Expressed in several structures, including hermaphrodite distal tip cell; intestine; pharyngeal muscle cell; spermatheca; and vulva. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 57. Is an ortholog of human MBOAT7 (membrane bound O-acyltransferase domain containing 7). WB:WBGene00008807 F14F3.4 Enriched in several structures, including G2; W cell; pharyngeal muscle cell; pharyngeal-intestinal valve; and rectal gland cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including 1-methylnicotinamide; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008808 ntr-2 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in RMEV; ganglia; intestine; and oblique male muscle. Human ortholog(s) of this gene implicated in several diseases, including ACTH-secreting pituitary adenoma; X-linked recessive disease (multiple); and portal hypertension. Is an ortholog of several human genes including AVPR1A (arginine vasopressin receptor 1A); AVPR1B (arginine vasopressin receptor 1B); and AVPR2 (arginine vasopressin receptor 2). WB:WBGene00008809 cyp-13A11 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00008810 cyp-13A12 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Expressed in marginal cell. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00008811 F14F7.4 Predicted to be located in membrane. WB:WBGene00008812 F14F7.5 Predicted to be located in membrane. WB:WBGene00008813 srz-2 Is affected by etr-1 and sir-2.1 based on RNA-seq and microarray studies. Is affected by resveratrol and dibromoacetic acid based on microarray studies. WB:WBGene00008814 srz-1 Predicted to be located in membrane. Expressed in chemosensory neurons and intestine. WB:WBGene00008815 srz-103 Predicted to be located in membrane. Expressed in ADLL; ADLR; neurons; and ventral nerve cord. WB:WBGene00008816 F14F8.8 Enriched in body wall muscle cell; cholinergic neurons; germ line; hypodermis; and pharyngeal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including Mercuric Chloride; Tunicamycin; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00008817 F14F8.9 Is affected by several genes including sir-2.1; clk-1; and prg-1 based on tiling array and microarray studies. Is affected by Diazinon; Sirolimus; and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: Smr domain and Smr domain superfamily. WB:WBGene00008818 srz-101 Predicted to be located in membrane. WB:WBGene00008819 shw-1 Predicted to enable delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in somatodendritic compartment and synapse. Predicted to be part of voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; brain disease (multiple); and glioblastoma. Is an ortholog of human KCNC1 (potassium voltage-gated channel subfamily C member 1); KCNC2 (potassium voltage-gated channel subfamily C member 2); and KCNC4 (potassium voltage-gated channel subfamily C member 4). WB:WBGene00008820 nlp-55 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00008821 best-12 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00008822 F14H3.3 Enriched in BAG; germ line; hypodermis; and interneuron based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including Tunicamycin; D-glucose; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00008823 F14H3.4 Enriched in several structures, including MSaapapa; MSpapapa; anterior ganglion (post); germ line; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008824 F14H3.5 Enriched in PVT; cephalic sheath cell; germ line; hypodermis; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including Lithium Chloride; rotenone; and 4-bromodiphenyl ether based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008825 F14H3.6 Enriched in several structures, including ABplapaaap; MSaapapa; MSpapapa; germ line; and neuronal sheath cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twelve chemicals including rotenone; Zidovudine; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008826 fbxa-100 Enriched in germ line; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including elt-2; npr-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride; resveratrol; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00008827 F14H3.8 Is affected by several genes including sir-2.1; pgl-1; and nhr-49 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00008828 F14H3.9 Is affected by hpl-2; rsr-2; and ngn-1 based on tiling array and RNA-seq studies. Is affected by cadmium based on microarray studies. WB:WBGene00008829 cyp-35D1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2E1 (cytochrome P450 family 2 subfamily E member 1); and CYP2S1 (cytochrome P450 family 2 subfamily S member 1). WB:WBGene00008830 nhr-176 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00008831 F14H3.12 Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00008832 obr-2 Predicted to enable sterol binding activity and sterol transporter activity. Predicted to be involved in sterol transport. Predicted to be located in cytosol; perinuclear endoplasmic reticulum; and plasma membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 67. Is an ortholog of human OSBPL2 (oxysterol binding protein like 2). WB:WBGene00008833 F14H8.2 Expressed in XXXL and XXXR. WB:WBGene00008834 F14H8.4 Enriched in NSM; XXXL; and XXXR based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and daf-18 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00008835 F14H8.5 Enriched in NSM; XXXL; and XXXR based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00008836 F15A2.7 No description available WB:WBGene00008837 sre-38 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00008838 F15A4.2 Enriched in several structures, including ABalaaaala; ABalaapaaa; RMED; amphid neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; mianserin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00008839 sre-37 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00008840 F15A4.5 Predicted to be located in membrane. WB:WBGene00008841 phat-8 Expressed in pharyngeal gland cell. Is predicted to encode a protein with the following domains: CC domain; ShK domain-like; and ShKT domain. WB:WBGene00008842 chil-28 Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008843 arrd-9 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC5 (arrestin domain containing 5). WB:WBGene00008844 F15A4.10 Enriched in several structures, including NSM; alimentary muscle; germ line; head neurons; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including hydrogen sulfide; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00008847 fbxb-102 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and ciliated neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; multi-walled carbon nanotube; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00008848 inft-2 Predicted to be involved in actin filament polymerization. Predicted to be located in actin filament. Expressed in excretory cell. WB:WBGene00008849 try-10 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. WB:WBGene00008850 F15B9.6 Predicted to be located in membrane. WB:WBGene00008851 F15B9.8 Enriched in several structures, including ABarpaapap; ABarpaappa; anterior hypodermis; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-five chemicals including Ethanol; Nitric Oxide; and methylmercury hydroxide based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; Thrombospondin type 1 domain; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00008852 ubql-1 Predicted to enable polyubiquitin modification-dependent protein binding activity. Involved in negative regulation of double-strand break repair via homologous recombination; protein export from nucleus; and response to endoplasmic reticulum stress. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 15. Is an ortholog of human UBQLN1 (ubiquilin 1). WB:WBGene00008853 clec-101 Enriched in NSM; dopaminergic neurons; and excretory gland cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and glh-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; nanoparticle; and sucrose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; C-type lectin-like; von Willebrand factor A-like domain superfamily; C-type lectin-like/link domain superfamily; Lectin C-type domain; and C-type lectin fold. WB:WBGene00008854 F15D3.4 Predicted to be located in extracellular space. WB:WBGene00008855 F15D3.5 Enriched in intestine based on microarray studies. Is affected by several genes including eat-2; sir-2.1; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is affected by Rifampin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00008856 F15D3.6 Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human PRELID3B (PRELI domain containing 3B). WB:WBGene00008857 timm-23 Predicted to enable mitochondrion targeting sequence binding activity and protein transmembrane transporter activity. Involved in protein import into mitochondrial matrix. Predicted to be located in membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is an ortholog of human TIMM23 (translocase of inner mitochondrial membrane 23). WB:WBGene00008858 pals-1 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and ABarpppapa based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including tryptophan; Tunicamycin; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00008859 F15D4.2 Predicted to be involved in regulation of apoptotic process. Is an ortholog of human CAAP1 (caspase activity and apoptosis inhibitor 1). WB:WBGene00008860 romo-1 Predicted to be involved in protein import into mitochondrial matrix and protein insertion into mitochondrial inner membrane. Predicted to be located in membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is an ortholog of human ROMO1 (reactive oxygen species modulator 1). WB:WBGene00008861 F15D4.4 Predicted to enable cysteine-type endopeptidase activator activity involved in apoptotic process and cysteine-type endopeptidase activity. Predicted to be involved in immune response; positive regulation of apoptotic signaling pathway; and proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Expressed in pharyngeal gland cell. WB:WBGene00008862 F15D4.5 Expressed in g1AL; g1AR; g2L; and g2R. WB:WBGene00008863 F15D4.6 Enriched in coelomocyte; germ line; germline precursor cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008864 F15D4.7 No description available WB:WBGene00008865 F15G9.1 Located in striated muscle dense body and striated muscle thin filament. Expressed in hypodermis and muscle cell. WB:WBGene00008866 F15G9.2 Enriched in intestine and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including hydrogen sulfide; resveratrol; and Atrazine based on microarray studies. WB:WBGene00008868 F15G9.5 Predicted to be located in membrane. WB:WBGene00008869 F15G9.6 Enriched in germ line and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including aak-2; hpl-2; and drh-3 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008870 F15H9.1 Enriched in amphid sheath cell; germ line; head mesodermal cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on proteomic; microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Nematode trypsin-6-like family and Chymotrypsin family Peptidase-S1. WB:WBGene00008871 tag-314 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including autophagy of mitochondrion; regulation of cellular response to oxidative stress; and regulation of protein metabolic process. Predicted to be located in Golgi apparatus; cytosol; and endoplasmic reticulum. Predicted to be part of ubiquitin ligase complex. WB:WBGene00008872 F15H10.5 Is affected by several genes including mir-34; smn-1; and emb-4 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; Mercuric Chloride; and nanoparticle based on microarray and RNA-seq studies. WB:WBGene00008873 F15H10.6 Enriched in DA neuron and VA neuron based on tiling array studies. Is affected by several genes including skn-1; lin-4; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00008874 F15H10.7 Predicted to be located in membrane. WB:WBGene00008875 F15H10.8 Predicted to be located in membrane. WB:WBGene00008876 F16A11.1 Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in cytoplasm. Is an ortholog of human RSPRY1 (ring finger and SPRY domain containing 1). WB:WBGene00008877 rtcb-1 Enables RNA ligase (ATP) activity. Involved in IRE1-mediated unfolded protein response and tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate. Acts upstream of or within with a positive effect on germ cell development and vulval development. Located in cytoplasm and nucleus. Used to study Parkinson's disease. Is an ortholog of human RTCB (RNA 2',3'-cyclic phosphate and 5'-OH ligase). WB:WBGene00008878 ppfr-1 Enables protein domain specific binding activity. Involved in embryo development; organelle organization; and regulation of spindle elongation. Located in cytoplasm. Expressed in several structures, including intestine; neurons; pharynx; ventral nerve cord; and vulval muscle. Is an ortholog of human PPP4R1 (protein phosphatase 4 regulatory subunit 1). WB:WBGene00008879 F16B12.1 Predicted to be located in membrane. WB:WBGene00008880 F16B12.4 Enriched in several structures, including Z1.p; coelomocyte; intestine; male distal tip cell; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eight chemicals including 1-methylnicotinamide; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00008881 F16B12.5 Enriched in ABalpapaap; ABarappaap; and IL socket cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008882 F16B12.6 Enriched in several structures, including ABalpapppa; ABarapappa; germ line; intestine; and somatic gonad precursor based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including dpy-10; daf-12; and eat-2 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by nine chemicals including Cry5B; silicon dioxide nanoparticle; and Doxycycline based on microarray; proteomic; and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008883 F16B12.7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00008884 nhr-281 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00008885 F16C3.1 Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection. Expressed in AIYL and AIYR. WB:WBGene00008886 F16C3.2 Enriched in gonadal sheath cell; hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including rotenone; D-glucose; and indole based on RNA-seq and microarray studies. WB:WBGene00008887 tbcd-1 Predicted to enable GTPase activator activity and beta-tubulin binding activity. Involved in microtubule cytoskeleton organization. Predicted to be located in lateral plasma membrane. Human ortholog(s) of this gene implicated in early onset progressive encephalopathy with brain atrophy and thin corpus callosum. Is an ortholog of human TBCD (tubulin folding cofactor D). WB:WBGene00008888 F16D3.5 No description available WB:WBGene00008889 F16D3.6 Predicted to be located in membrane. WB:WBGene00008890 ser-5 Predicted to enable alpha1-adrenergic receptor activity. Involved in several processes, including pharyngeal pumping; positive regulation of egg-laying behavior; and serotonin receptor signaling pathway. Predicted to be located in membrane. Expressed in body wall musculature; egg-laying apparatus; and lateral ganglion. Human ortholog(s) of this gene implicated in Alzheimer's disease and hypertension. Is an ortholog of human ADRA1A (adrenoceptor alpha 1A) and ADRA1B (adrenoceptor alpha 1B). WB:WBGene00008891 clec-42 Expressed in int1DL; int1DR; int1VL; int1VR; and neurons. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00008892 clec-246 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by cholesterol and triclosan based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00008893 F16H6.3 Enriched in g1P based on single-cell RNA-seq studies. Is affected by several genes including sir-2.1; eri-1; and mdt-15 based on microarray studies. Is affected by methylmercuric chloride based on microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00008894 F16H6.4 Predicted to enable cysteine-type peptidase activity. Predicted to be involved in proteolysis. WB:WBGene00008897 F16H6.7 Predicted to enable cysteine-type peptidase activity. Predicted to be involved in proteolysis. WB:WBGene00008898 F16H6.8 Enriched in pharyngeal muscle cell based on tiling array studies. Is affected by several genes including eat-2; sir-2.1; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00008899 F16H6.9 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by ten chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00008900 F16H6.10 Involved in innate immune response. WB:WBGene00008901 nhr-27 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Involved in determination of adult lifespan. Predicted to be located in nucleus. WB:WBGene00008902 phf-32 Predicted to enable metal ion binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. WB:WBGene00008903 F17A2.4 Is affected by eat-2 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00008904 F17A2.13 Enriched in several structures, including Z1.p; body wall muscle cell; germ line; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercury hydroxide; methylmercuric chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00008905 F17B5.1 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including Ethanol; Tunicamycin; and 4-bromodiphenyl ether based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Thioredoxin-like superfamily; and Thioredoxin-like. WB:WBGene00008906 oac-17 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00008907 clec-109 Is affected by several genes including rrf-3; lin-4; and lin-14 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00008908 F17B5.4 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00008909 clec-110 Is affected by several genes including eat-2; clk-1; and rrf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including iron oxide nanoparticle; Rifampin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00008910 F17C8.3 Enriched in germ line; muscle cell; and neurons based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq; microarray; and proteomic studies. Is affected by nine chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00008911 F17C8.6 Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Human ortholog(s) of this gene implicated in congenital limbs-face contractures-hypotonia-developmental delay syndrome. Is an ortholog of human NALCN (sodium leak channel, non-selective). WB:WBGene00008912 F17C8.7 Enriched in germ line; somatic gonad precursor; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; pie-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Heme; D-glucose; and stavudine based on microarray and RNA-seq studies. WB:WBGene00008914 F17C11.2 Expressed in AIYL and AIYR. WB:WBGene00008915 F17C11.4 Enriched in several structures, including GLR; MSpppaaa; coelomocyte; head mesodermal cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including D-glucose; tert-Butylhydroperoxide; and Psoralens based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00008916 clec-221 Enriched in AIZL; AIZR; and male-specific anatomical entity based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including Tunicamycin; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00008917 F17C11.6 Predicted to be located in membrane. WB:WBGene00008918 pigt-1 Predicted to be involved in attachment of GPI anchor to protein. Predicted to be located in membrane. Predicted to be part of GPI-anchor transamidase complex. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 3 and paroxysmal nocturnal hemoglobinuria. Is an ortholog of human PIGT (phosphatidylinositol glycan anchor biosynthesis class T). WB:WBGene00008919 vps-36 Predicted to enable ubiquitin binding activity. Predicted to be involved in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be located in late endosome membrane. Predicted to be part of ESCRT II complex. Expressed in pharyngeal muscle cell. Is an ortholog of human VPS36 (vacuolar protein sorting 36 homolog). WB:WBGene00008920 eef-1G Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human EEF1G (eukaryotic translation elongation factor 1 gamma). WB:WBGene00008921 ctf-4 Predicted to enable chromatin binding activity. Predicted to be involved in DNA repair; DNA-templated DNA replication; and mitotic cell cycle. Predicted to be located in nuclear replication fork. Predicted to be part of replication fork protection complex. Human ortholog(s) of this gene implicated in cholangiocarcinoma. Is an ortholog of human WDHD1 (WD repeat and HMG-box DNA binding protein 1). WB:WBGene00008922 F17C11.11 Enriched in body wall musculature; g2; intestine; neurons; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; Tunicamycin; and levamisole based on RNA-seq; microarray; and proteomic studies. WB:WBGene00008923 F17C11.12 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00008924 F17E5.2 Predicted to enable ATP transmembrane transporter activity. Predicted to be involved in ADP transport and ATP transport. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human SLC25A25 (solute carrier family 25 member 25). WB:WBGene00008925 F17H10.1 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and D-glucopyranose based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome. Is predicted to encode a protein with the following domain: Alpha/Beta hydrolase fold. Is an ortholog of human SERAC1 (serine active site containing 1). WB:WBGene00008926 F17H10.2 Predicted to be located in membrane. WB:WBGene00008927 snx-17 Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in intracellular protein transport. Predicted to be located in early endosome. Is an ortholog of human SNX17 (sorting nexin 17). WB:WBGene00008928 F17H10.4 Predicted to be located in membrane. WB:WBGene00008929 F18A11.2 Enriched in head mesodermal cell; hypodermis; seam cell; and tail precursor cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eleven chemicals including Ethanol; mianserin; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: CRAL-TRIO lipid binding domain; CRAL-TRIO lipid binding domain superfamily; and CRAL/TRIO domain. WB:WBGene00008930 F18A11.3 Enriched in coelomocyte; head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; sir-2.1; and aak-2 based on RNA-seq and microarray studies. Is affected by five chemicals including hydrogen sulfide; rotenone; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Uncharacterised protein family UPF0729. Is an ortholog of human C18orf32 (chromosome 18 open reading frame 32). WB:WBGene00008932 F18A11.5 Predicted to be involved in protein homooligomerization. WB:WBGene00008933 F18A11.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; glp-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00008934 F18C12.3 Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in nucleus. Predicted to be part of 90S preribosome. Is an ortholog of human SRFBP1 (serum response factor binding protein 1). WB:WBGene00008935 F18C12.4 Predicted to be located in membrane. WB:WBGene00008936 papl-1 Predicted to enable acid phosphatase activity and metal ion binding activity. WB:WBGene00008937 srt-43 Predicted to be located in membrane. WB:WBGene00008939 F18H3.1 Expressed in head neurons; pharyngeal neurons; and sensory neurons. Is predicted to encode a protein with the following domains: Concanavalin A-like lectin/glucanase domain superfamily; SPRY domain-containing protein 7; SPRY domain; and B30.2/SPRY domain superfamily. Is an ortholog of human SPRYD7 (SPRY domain containing 7). WB:WBGene00008940 F18H3.4 Predicted to enable mRNA binding activity. Involved in IRE1-mediated unfolded protein response and innate immune response. Predicted to be located in endoplasmic reticulum and nuclear outer membrane-endoplasmic reticulum membrane network. Predicted to be part of ribonucleoprotein complex. WB:WBGene00008941 srz-33 Enriched in AVK based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00008942 srz-34 Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. WB:WBGene00008943 srz-36 Is affected by several genes including lin-15B; hpl-2; and cyc-1 based on microarray and RNA-seq studies. Is affected by Rifampin; dibromoacetic acid; and nitroguanidine based on RNA-seq and microarray studies. WB:WBGene00008944 F19B2.5 Predicted to enable ATP binding activity and ATP-dependent chromatin remodeler activity. Predicted to be involved in chromatin remodeling. WB:WBGene00008945 F19B2.6 Enriched in several structures, including PLM; XXX cell; carbon dioxide sensory neurons; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and aak-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including 1-methylnicotinamide; stavudine; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00008946 F19B2.7 Predicted to enable ATP binding activity; ATP-dependent peptidase activity; and serine-type endopeptidase activity. Predicted to be involved in protein processing and protein targeting to peroxisome. Predicted to be located in peroxisomal matrix. WB:WBGene00008947 srz-16 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00008948 F19B6.1 Predicted to enable ATP binding activity; cytidine kinase activity; and uridine kinase activity. Involved in embryo development. Predicted to be located in cytoplasm. Is an ortholog of human UCKL1 (uridine-cytidine kinase 1 like 1). WB:WBGene00008949 F19B6.3 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including rrf-3; sir-2.1; and npr-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; Psoralens; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00008950 wht-5 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in positive regulation of nematode male tail tip morphogenesis. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including gout; hematologic cancer (multiple); and toxic encephalopathy. Is an ortholog of human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)). WB:WBGene00008951 F19C6.2 Predicted to be located in nucleus. Is an ortholog of human ECD (ecdysoneless cell cycle regulator). WB:WBGene00008952 F19C6.3 Predicted to enable calcium ion binding activity. WB:WBGene00008953 F19C6.4 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00008954 F19C6.5 Predicted to be located in membrane. WB:WBGene00008955 F19D8.2 Enriched in several structures, including ABalpapaap; ABarappaap; male distal tip cell; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00008956 nekl-3 Predicted to enable protein serine/threonine kinase activity. Involved in gonad development and molting cycle. Located in apical plasma membrane. Expressed in hyp7 syncytium; hypodermal cell; neurons; and vulva. Is an ortholog of human NEK7 (NIMA related kinase 7). WB:WBGene00008957 glb-13 Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Expressed in head; somatic nervous system; and tail neurons. WB:WBGene00008958 rif-1.2 Predicted to be involved in telomere maintenance. Predicted to be located in nucleus. Is an ortholog of human RIF1 (replication timing regulatory factor 1). WB:WBGene00008959 F19H6.4 Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in steroid biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in breast carcinoma; hypospadias; and prostate disease (multiple). Is an ortholog of human SRD5A2 (steroid 5 alpha-reductase 2). WB:WBGene00008960 F19H6.5 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and let-7 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Tunicamycin; and stavudine based on microarray and RNA-seq studies. WB:WBGene00008961 F19H6.6 Enriched in AFD; ASER; excretory gland cell; neurons; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; Zidovudine; and allantoin based on microarray and RNA-seq studies. WB:WBGene00008963 F19H8.2 Enriched in CEP socket cell; arc ant V; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including tryptophan; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00008964 mltn-9 Enriched in excretory system; hypodermis; sensory neurons; and ventral cord blast cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including methylmercury hydroxide; rotenone; and juglone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Moulting cycle MLT-10-like protein and Moulting cycle. WB:WBGene00008965 mltn-10 Predicted to be located in membrane. WB:WBGene00008966 F20B10.2 Is affected by several genes including daf-16; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00008967 F20B10.3 Enriched in several structures, including MSaapapa; MSpapapa; arcade cell; cholinergic neurons; and pharyngeal-intestinal valve based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00008968 elli-1 Involved in P granule assembly and embryo development. Located in cytoplasm. WB:WBGene00008969 cdc-50.B Involved in innate immune response. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Is an ortholog of human TMEM30B (transmembrane protein 30B). WB:WBGene00008970 F20C5.5 Enriched in ABalaapppa; ABalapaapa; ABprpapppa; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00008971 F20C5.6 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABplpaaaaa; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-four chemicals including 1-methylnicotinamide; rotenone; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00008972 F20C5.7 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00008973 flwr-1 Predicted to enable calcium channel activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in synaptic vesicle membrane. Expressed in several structures, including anterior gonad arm. Is an ortholog of human CACFD1 (calcium channel flower domain containing 1). WB:WBGene00008974 tbc-1 Predicted to be involved in retrograde transport, endosome to Golgi and vesicle tethering to Golgi. Predicted to be located in trans-Golgi network. Expressed in anterior gonad arm. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 11. Is an ortholog of human TBC1D23 (TBC1 domain family member 23). WB:WBGene00008975 F20D1.3 Expressed in anterior gonad arm. Is predicted to encode a protein with the following domain: Kelch-type beta propeller. WB:WBGene00008976 plp-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and purine-rich negative regulatory element binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human PURB (purine rich element binding protein B) and PURG (purine rich element binding protein G). WB:WBGene00008977 iglr-1 Predicted to be located in membrane. Expressed in head neurons and ventral nerve cord. WB:WBGene00008978 cutl-3 Predicted to be located in membrane. WB:WBGene00008979 slc-25A18.1 Predicted to enable L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport; aspartate transmembrane transport; and malate-aspartate shuttle. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 3. Is an ortholog of human SLC25A18 (solute carrier family 25 member 18) and SLC25A22 (solute carrier family 25 member 22). WB:WBGene00008980 emre-1 Involved in mitochondrial calcium ion homeostasis and mitochondrial calcium ion transmembrane transport. Located in mitochondrion. Is an ortholog of human SMDT1 (single-pass membrane protein with aspartate rich tail 1). WB:WBGene00008981 srz-48 Predicted to be located in membrane. WB:WBGene00008982 srsx-2 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00008983 F20E11.5 Enriched in NSM based on tiling array studies. Is affected by several genes including drh-3; mrg-1; and cyc-1 based on microarray; tiling array; and RNA-seq studies. WB:WBGene00008984 F20E11.7 Is affected by several genes including daf-12; eri-1; and rrf-1 based on microarray; tiling array; and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00008985 F20G2.1 Predicted to enable oxidoreductase activity. Predicted to be located in cytoplasm. Is an ortholog of human CBR1 (carbonyl reductase 1) and CBR3 (carbonyl reductase 3). WB:WBGene00008986 F20G2.2 Predicted to enable oxidoreductase activity. Predicted to be located in cytoplasm. Is an ortholog of human CBR1 (carbonyl reductase 1) and CBR3 (carbonyl reductase 3). WB:WBGene00008987 F20G2.3 Enriched in several structures, including anterior hypodermis; germ line; germline precursor cell; interfacial epithelial cell; and sensory neurons based on microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; proteomic; and RNA-seq studies. Is affected by nineteen chemicals including methylmercury hydroxide; manganese chloride; and D-glucose based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: GOLD domain superfamily. WB:WBGene00008988 F20G2.5 Involved in defense response to Gram-negative bacterium and innate immune response. WB:WBGene00008989 F20G2.6 Predicted to be located in membrane. WB:WBGene00008990 smgl-1 Predicted to enable SNARE binding activity. Involved in nuclear-transcribed mRNA catabolic process. Predicted to be part of Dsl1/NZR complex. Human ortholog(s) of this gene implicated in infantile liver failure syndrome. Is an ortholog of human NBAS (NBAS subunit of NRZ tethering complex). WB:WBGene00008991 F20G4.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00008992 F21A3.2 Predicted to be located in membrane. WB:WBGene00008993 F21A3.3 Enriched in several structures, including ABplppppaa; AFD; interfacial epithelial cell; rectal gland cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including rotenone; D-glucose; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain; Nitrobindin family; ShK domain-like; THAP4-like, heme-binding beta-barrel domain; and Calycin. WB:WBGene00008994 F21A3.4 Enriched in RIAL; RIAR; germ line; neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; manganese chloride; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00008995 prde-1 Predicted to enable protein serine/threonine kinase activity. Involved in positive regulation of piRNA transcription. Located in autosome. Expressed in PLML; PLMR; and germ cell. WB:WBGene00008996 glb-14 Predicted to enable heme binding activity and oxidoreductase activity. Predicted to be involved in oxygen transport. Expressed in VC neuron; head neurons; and vulval muscle. Human ortholog(s) of this gene implicated in COVID-19 and acute kidney failure. Is an ortholog of human CYGB (cytoglobin). WB:WBGene00008997 lgc-31 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00008998 ncs-4 Predicted to enable calcium ion binding activity. Expressed in body wall musculature; diagonal muscle; head neurons; tail neurons; and vulval muscle. WB:WBGene00008999 myrf-2 Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in positive regulation of DNA-templated transcription and protein autoprocessing. Predicted to be located in endoplasmic reticulum membrane and nucleus. Human ortholog(s) of this gene implicated in cerebral infarction; congenital diaphragmatic hernia; and eye disease (multiple). Is an ortholog of human MYRF (myelin regulatory factor) and MYRFL (myelin regulatory factor like). WB:WBGene00009000 arrd-28 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. WB:WBGene00009001 tyr-3 Predicted to enable metal ion binding activity and monooxygenase activity. Expressed in head mesodermal cell. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human DCT (dopachrome tautomerase) and TYR (tyrosinase). WB:WBGene00009002 hint-1 Predicted to enable hydrolase activity. Predicted to be involved in purine ribonucleotide catabolic process. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Gamstorp-Wohlfart syndrome. Is an ortholog of human HINT1 (histidine triad nucleotide binding protein 1). WB:WBGene00009004 pfd-6 Predicted to enable protein-folding chaperone binding activity. Predicted to be involved in chaperone-mediated protein complex assembly and protein folding. Located in cytoplasm. Expressed in body wall musculature; hypodermal cell; intestinal cell; and non-striated muscle. Is an ortholog of human PFDN6 (prefoldin subunit 6). WB:WBGene00009005 F21C3.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; antimycin; and paraquat based on microarray and RNA-seq studies. WB:WBGene00009006 F21D5.1 Predicted to enable phosphoacetylglucosamine mutase activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process. Human ortholog(s) of this gene implicated in cervical cancer; immunodeficiency 23; and teratoma. Is an ortholog of human PGM3 (phosphoglucomutase 3). WB:WBGene00009007 otub-3 Predicted to enable cysteine-type deubiquitinase activity. Is an ortholog of human OTUD6A (OTU deubiquitinase 6A) and OTUD6B (OTU deubiquitinase 6B). WB:WBGene00009008 F21D5.3 Predicted to enable oxidoreductase activity. Predicted to be involved in iron ion transport. Predicted to be located in plasma membrane. WB:WBGene00009009 F21D5.4 Predicted to enable sequence-specific DNA binding activity. Is an ortholog of human POGK (pogo transposable element derived with KRAB domain). WB:WBGene00009010 F21D5.5 Enables double-stranded DNA binding activity. Predicted to be involved in DNA repair. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B2 and microcephaly, seizures, and developmental delay. Is an ortholog of human PNKP (polynucleotide kinase 3'-phosphatase). WB:WBGene00009011 F21D5.6 Predicted to be involved in RNA catabolic process. Predicted to be located in nucleoplasm. Predicted to be part of ribonuclease H2 complex. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Is an ortholog of human RNASEH2B (ribonuclease H2 subunit B). WB:WBGene00009012 F21D5.7 Predicted to enable 7S RNA binding activity and endoplasmic reticulum signal peptide binding activity. Predicted to contribute to GTPase activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation. Predicted to be located in cytosol. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Human ortholog(s) of this gene implicated in severe congenital neutropenia 8. Is an ortholog of human SRP54 (signal recognition particle 54). WB:WBGene00009013 mrps-33 Predicted to be located in mitochondrion. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human MRPS33 (mitochondrial ribosomal protein S33). WB:WBGene00009014 F21D5.9 Expressed in epithelial cell. WB:WBGene00009015 F21D9.1 Enriched in several structures, including ABalpapppa; ABalppappa; germ line; nerve ring neurons; and pharyngeal neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00009016 F21D9.2 Predicted to be located in membrane. WB:WBGene00009017 F21D9.3 Enriched in body wall muscle cell and coelomocyte based on tiling array studies. Is affected by several genes including daf-2; eat-2; and alg-1 based on tiling array and microarray studies. Is affected by nine chemicals including methylmercuric chloride; Chlorpyrifos; and Diazinon based on microarray studies. WB:WBGene00009018 F21D9.4 Enriched in muscle cell and touch receptor neurons based on tiling array; microarray; and single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by eleven chemicals including D-glucose; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; YitH/HolE, acetyltransferase (GNAT) domain; and Acetyltransferase (GNAT) domain. WB:WBGene00009019 F21D9.5 Enriched in pharynx based on microarray studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by Rifampin; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00009020 F21D9.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00009021 F21D9.8 Enriched in DA neuron and VA neuron based on tiling array studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009023 F21G4.1 Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Expressed in socket cell. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); primary hypertrophic osteoarthropathy; and reproductive organ cancer (multiple). Is an ortholog of human SLCO2A1 (solute carrier organic anion transporter family member 2A1). WB:WBGene00009024 F21G4.3 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00009025 phf-34 Predicted to enable metal ion binding activity. Predicted to be located in nucleus. WB:WBGene00009026 F21G4.5 Enriched in I5 neuron; Z1; Z4; neurons; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and let-60 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00009027 F21G4.6 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Huntington's disease and Parkinson's disease. Is an ortholog of human HTT (huntingtin). WB:WBGene00009028 F21H7.2 Enriched in coelomocyte; germ line; muscle cell; sensory neurons; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00009029 F21H7.3 Predicted to be located in membrane. Expressed in body wall musculature. WB:WBGene00009030 clec-233 Enriched in several structures, including germ line; head mesodermal cell; muscle cell; pharyngeal-intestinal valve cell; and rectal gland cell based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including manganese chloride; stavudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00009031 F21H7.5 Predicted to be located in cytoskeleton. WB:WBGene00009032 bgnt-1.3 Enriched in germ line; hypodermis; and seam cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on RNA-seq; microarray; and proteomic studies. Is affected by twelve chemicals including Ethanol; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A13. Human B4GAT1 enables glucuronosyltransferase activity. Is predicted to encode a protein with the following domain: Glycosyl-transferase for dystroglycan. Is an ortholog of human B4GAT1 (beta-1,4-glucuronyltransferase 1). WB:WBGene00009033 F21H7.12 Predicted to be located in membrane. WB:WBGene00009034 F22B3.3 No description available WB:WBGene00009035 gfat-2 Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in UDP-N-acetylglucosamine metabolic process and fructose 6-phosphate metabolic process. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12; obesity; and type 2 diabetes mellitus. Is an ortholog of human GFPT1 (glutamine--fructose-6-phosphate transaminase 1). WB:WBGene00009036 F22B3.5 Predicted to be located in membrane. WB:WBGene00009037 F22B3.6 No description available WB:WBGene00009038 F22B3.7 Is affected by several genes including rrf-3; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; D-glucose; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00009039 F22B3.8 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00009041 cut-3 Predicted to be a structural constituent of cuticle. Predicted to be located in plasma membrane. WB:WBGene00009042 F22B5.4 Predicted to be located in membrane. WB:WBGene00009043 F22B5.5 Enriched in several structures, including AIY; FLP; MSpppaaa; germ line; and head mesodermal cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; D-glucose; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF1248 and Protein of unknown function (DUF1248). WB:WBGene00009044 F22B5.6 Predicted to be located in membrane. WB:WBGene00009045 F22B5.10 Predicted to enable calcium channel activity. Involved in calcium ion transmembrane transport and endoplasmic reticulum calcium ion homeostasis. Located in striated muscle dense body. Human ortholog(s) of this gene implicated in craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 1. Is an ortholog of human TMCO1 (transmembrane and coiled-coil domains 1). WB:WBGene00009046 F22B8.3 Predicted to be located in membrane. WB:WBGene00009047 F22B8.4 Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00009048 cth-1 Predicted to enable cystathionine gamma-lyase activity and pyridoxal phosphate binding activity. Predicted to be involved in cysteine biosynthetic process via cystathionine and transsulfuration. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in cystathioninuria. Is an ortholog of human CTH (cystathionine gamma-lyase). WB:WBGene00009049 F22B8.7 Predicted to enable catalytic activity; molybdenum ion binding activity; and pyridoxal phosphate binding activity. Involved in regulation of protein deneddylation. Located in cytoplasm and nucleus. Is an ortholog of human MTARC1 (mitochondrial amidoxime reducing component 1) and MTARC2 (mitochondrial amidoxime reducing component 2). WB:WBGene00009050 mstr-1 Predicted to enable DNA binding activity and zinc ion binding activity. Located in nucleus. Is an ortholog of human ZFAND5 (zinc finger AN1-type containing 5) and ZFAND6 (zinc finger AN1-type containing 6). WB:WBGene00009051 nduf-6 Involved in mitochondrial electron transport, NADH to ubiquinone and response to xenobiotic stimulus. Located in mitochondrion. Human ortholog(s) of this gene implicated in cervical cancer and nuclear type mitochondrial complex I deficiency 9. Is an ortholog of human NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6). WB:WBGene00009052 ekl-1 Involved in P granule assembly and siRNA processing. Located in condensed nuclear chromosome; cytoplasm; and metaphase plate. WB:WBGene00009054 F22D6.9 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00009055 F22D6.14 Enriched in germ line based on RNA-seq studies. Is affected by several genes including fog-2; aak-2; and atfs-1 based on microarray and RNA-seq studies. Is affected by four chemicals including stavudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00009056 F22D6.15 Enriched in AFD; AMshL; AMshR; PLM; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including clk-1; aak-2; and isp-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Immunoglobulin-like fold. WB:WBGene00009057 cept-1 Predicted to enable diacylglycerol cholinephosphotransferase activity and ethanolaminephosphotransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be located in Golgi apparatus and endoplasmic reticulum membrane. Is an ortholog of human CHPT1 (choline phosphotransferase 1). WB:WBGene00009058 F22E12.1 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular space. WB:WBGene00009059 chw-1 Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in establishment or maintenance of cell polarity and vulval development. Predicted to be located in plasma membrane. Expressed in several structures, including P3.pa; P3.pp; P4.pa; P4.pp; and P8.pa. Is an ortholog of human RHOU (ras homolog family member U). WB:WBGene00009060 F22E12.3 Predicted to be located in membrane. WB:WBGene00009061 pals-14 Enriched in dopaminergic neurons and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including Nitric Oxide; Ethanol; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00009062 F22G12.2 No description available WB:WBGene00009063 F22G12.3 Enriched in several structures, including ABalppappa; ABarappppa; ABplpaappa; ABplppaapa; and ADE sheath cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; rotenone; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00009064 F22G12.4 Predicted to enable 1-phosphatidylinositol binding activity. Is an ortholog of human ANKFY1 (ankyrin repeat and FYVE domain containing 1). WB:WBGene00009065 F22G12.5 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Expressed in spermatheca and uterine toroidal epithelial cell. Is an ortholog of human DOCK11 (dedicator of cytokinesis 11). WB:WBGene00009067 F23A7.1 Predicted to be located in membrane. WB:WBGene00009068 F23A7.3 Enriched in ABplapaaap; ABprapaaap; coelomocyte; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including rotenone; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00009069 F23A7.4 Enriched in several structures, including MSaapaapa; MSpapaapa; excretory cell; germ line; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including hydrogen sulfide; Ethanol; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00009070 F23A7.5 Enriched in head mesodermal cell; neurons; and pharynx based on microarray and RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and aak-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00009071 F23A7.6 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00009072 F23A7.7 No description available WB:WBGene00009073 delm-1 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of human ASIC1 (acid sensing ion channel subunit 1); ASIC2 (acid sensing ion channel subunit 2); and ASIC3 (acid sensing ion channel subunit 3). WB:WBGene00009075 F23B2.7 Predicted to be located in membrane. Expressed in gonad. WB:WBGene00009076 F23B2.8 Enriched in AVK based on RNA-seq studies. Is affected by rsr-2 based on tiling array studies. WB:WBGene00009077 F23B2.10 Predicted to enable metal ion binding activity. WB:WBGene00009078 rpb-12 Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and zinc ion binding activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase I; transcription by RNA polymerase II; and transcription by RNA polymerase III. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Is an ortholog of human POLR2K (RNA polymerase II, I and III subunit K). WB:WBGene00009079 F23B12.1 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00009081 F23B12.4 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalappaap; ABalapppaa; and PLM based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty chemicals including Lithium Chloride; hydrogen sulfide; and methylmercury hydroxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Reeler domain superfamily and Reeler domain. WB:WBGene00009082 dlat-1 Predicted to enable dihydrolipoyllysine-residue acetyltransferase activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Predicted to be located in mitochondrial matrix. Predicted to be part of mitochondrial pyruvate dehydrogenase complex. Expressed in several structures, including head and tail. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Is an ortholog of human DLAT (dihydrolipoamide S-acetyltransferase). WB:WBGene00009084 F23B12.7 Predicted to be located in nucleus. Is an ortholog of human CEBPZ (CCAAT enhancer binding protein zeta). WB:WBGene00009085 F23D12.1 Predicted to be located in membrane. WB:WBGene00009086 F23D12.2 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including D-glucose; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00009087 F23D12.3 Enriched in intestine and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; D-glucose; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5354 and Family of unknown function (DUF5354). WB:WBGene00009088 F23D12.4 Enriched in ABaraapapaa; ABaraapppaa; AVL; arcade cell; and body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including methylmercuric chloride; Alovudine; and allantoin based on microarray and RNA-seq studies. WB:WBGene00009089 jmjd-3.2 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; chromatin DNA binding activity; and histone H3K27me2/H3K27me3 demethylase activity. Predicted to be involved in regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of MLL3/4 complex. WB:WBGene00009090 fipr-3 Predicted to be located in membrane. WB:WBGene00009091 F23D12.7 Enriched in mechanosensory neurons and muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including hydrogen sulfide; rotenone; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00009092 tomm-20 Predicted to enable mitochondrion targeting sequence binding activity. Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix and tRNA import into mitochondrion. Predicted to be located in mitochondrial outer membrane. Predicted to be part of mitochondrial outer membrane translocase complex. Is an ortholog of human TOMM20 (translocase of outer mitochondrial membrane 20). WB:WBGene00009093 F23H12.3 Predicted to be located in membrane. WB:WBGene00009094 F23H12.5 Predicted to be located in extracellular space. WB:WBGene00009095 F23H12.7 Predicted to be located in membrane. WB:WBGene00009096 fipr-1 Enriched in CEM; HOB; IL2 neuron; and ray neuron type B based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including nicotinic acid; rotenone; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00009097 fipr-2 Enriched in AIZ; I3 neuron; and arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; nicotinic acid; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00009098 ehbp-1 Enables small GTPase binding activity. Involved in endocytic recycling; protein secretion; and receptor recycling. Located in early endosome membrane and recycling endosome membrane. Expressed in several structures, including body wall musculature; hermaphrodite gonad; intestine; nerve ring; and pharynx. Is an ortholog of human EHBP1 (EH domain binding protein 1). WB:WBGene00009099 F25B3.2 Enriched in CEP and arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and lin-4 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Cystine-knot cytokine. WB:WBGene00009100 rgef-1 Enables guanyl-nucleotide exchange factor activity. Involved in chemotaxis and positive regulation of Ras protein signal transduction. Located in cytoplasm and intracellular membrane-bounded organelle. Expressed in excretory gland cell; nervous system; pharyngeal gland cell; rectal gland cell; and uv1. Human ortholog(s) of this gene implicated in hypertension; immunodeficiency 64; and platelet-type bleeding disorder 18. Is an ortholog of human RASGRP1 (RAS guanyl releasing protein 1); RASGRP2 (RAS guanyl releasing protein 2); and RASGRP3 (RAS guanyl releasing protein 3). WB:WBGene00009101 F25B3.4 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00009102 F25B3.5 Enriched in several structures, including ABplpppaaa; ABprpppaaa; B cell; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; 4-bromodiphenyl ether; and levamisole based on microarray and RNA-seq studies. WB:WBGene00009103 rtfo-1 Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity. Located in nucleus. Is an ortholog of human RTF1 (RTF1 homolog, Paf1/RNA polymerase II complex component). WB:WBGene00009104 F25C8.1 Is affected by several genes including rrf-3; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; Tunicamycin; and stavudine based on microarray and RNA-seq studies. WB:WBGene00009106 acs-12 Predicted to enable CoA-ligase activity. WB:WBGene00009107 txt-10 Predicted to be located in membrane. WB:WBGene00009108 F25D1.3 Predicted to enable cytokine activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Is an ortholog of human IL17A (interleukin 17A); IL17C (interleukin 17C); and IL17F (interleukin 17F). WB:WBGene00009109 degt-1 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Expressed in neurons. WB:WBGene00009110 F25D1.5 Predicted to enable nucleotide binding activity and oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00009112 tag-353 Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. Is an ortholog of human HERPUD2 (HERPUD family member 2). WB:WBGene00009113 maph-1.2 Predicted to enable actin binding activity and microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization; neuron projection development; and regulation of microtubule depolymerization. Predicted to be located in several cellular components, including cytosol; microtubule; and somatodendritic compartment. Predicted to be part of microtubule associated complex. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness and periventricular nodular heterotopia. Is an ortholog of human MAP1A (microtubule associated protein 1A); MAP1B (microtubule associated protein 1B); and MAP1S (microtubule associated protein 1S). WB:WBGene00009114 paml-2 Predicted to be involved in cytosolic ribosome assembly. Predicted to be located in membrane and mitochondrial matrix. WB:WBGene00009115 F25F2.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00009116 snx-27 Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in intracellular protein transport. Predicted to be located in early endosome. Is an ortholog of human SNX27 (sorting nexin 27). WB:WBGene00009117 F25H2.3 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-12; eat-2; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by Rifampin and Colistin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Ankyrin repeat-containing domain superfamily. WB:WBGene00009118 F25H2.4 Located in striated muscle dense body. Is an ortholog of human EMC8 (ER membrane protein complex subunit 8) and EMC9 (ER membrane protein complex subunit 9). WB:WBGene00009119 ndk-1 Enables identical protein binding activity and protein histidine kinase activity. Involved in several processes, including positive regulation of MAPK cascade; positive regulation of vulval development; and regulation of engulfment of apoptotic cell. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); prostatic hypertrophy; and teratoma. Is an ortholog of human NME1-NME2 (NME1-NME2 readthrough); NME2 (NME/NM23 nucleoside diphosphate kinase 2); and NME2P1 (NME2 pseudogene 1). WB:WBGene00009120 F25H2.6 Predicted to enable lipid binding activity. Predicted to be involved in ER to Golgi ceramide transport. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 34. Is an ortholog of human CERT1 (ceramide transporter 1). WB:WBGene00009121 F25H2.7 Predicted to enable transferase activity. WB:WBGene00009122 tct-1 Predicted to enable calcium ion binding activity. Located in endoplasmic reticulum. Is an ortholog of human TPT1 (tumor protein, translationally-controlled 1). WB:WBGene00009123 F25H2.12 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Located in striated muscle dense body. Is an ortholog of human METTL25B (methyltransferase like 25B). WB:WBGene00009124 rtel-1 Predicted to enable ATP binding activity; DNA helicase activity; and DNA polymerase binding activity. Involved in regulation of double-strand break repair via homologous recombination. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive dyskeratosis congenita 5; high grade glioma (multiple); and lung disease (multiple). Is an ortholog of human RTEL1 (regulator of telomere elongation helicase 1). WB:WBGene00009125 F25H5.2 Predicted to be located in membrane. WB:WBGene00009126 pyk-1 Predicted to enable pyruvate kinase activity. Predicted to be involved in glycolytic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including Gaucher's disease; pyruvate kinase deficiency of red cells; and type 2 diabetes mellitus. Is an ortholog of human PKM (pyruvate kinase M1/2). WB:WBGene00009127 clsp-1 Predicted to enable anaphase-promoting complex binding activity. Predicted to be involved in mitotic DNA replication checkpoint signaling and mitotic G2 DNA damage checkpoint signaling. Located in nucleus. Is an ortholog of human CLSPN (claspin). WB:WBGene00009128 mrpl-54 Predicted to be a structural constituent of ribosome. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL54 (mitochondrial ribosomal protein L54). WB:WBGene00009129 F25H5.7 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00009130 F25H5.8 Predicted to be located in membrane. WB:WBGene00009131 trmt-10A Predicted to enable tRNA (guanine-N1-)-methyltransferase activity and tRNA binding activity. Predicted to be involved in tRNA N1-guanine methylation. Predicted to be located in nucleoplasm. Is an ortholog of human TRMT10A (tRNA methyltransferase 10A). WB:WBGene00009132 F25H8.2 Predicted to enable RNA binding activity. Predicted to be involved in box H/ACA snoRNP assembly and ribosome biogenesis. Located in nucleus. Human ortholog(s) of this gene implicated in melanoma. Is an ortholog of human NAF1 (nuclear assembly factor 1 ribonucleoprotein). WB:WBGene00009133 bed-3 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in molting cycle; regulation of cell division; and vulval cell fate specification. Predicted to be located in nucleus. Expressed in M lineage cell; hypodermal cell; and vulval cell. WB:WBGene00009134 lurp-2 Enriched in ADL; ADLL; ADLR; ASH; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including sir-2.1; hpl-2; and ain-1 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ly-6 antigen/uPA receptor-like and Snake toxin-like superfamily. WB:WBGene00009135 F25H9.2 Enriched in germ line; intestine; neurons; rectal epithelial cell; and rectum based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including hydrogen sulfide; Zidovudine; and Doxycycline based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00009136 lurp-3 Enriched in ADL; ADLL; ADLR; PHA; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including sir-2.1; dpy-21; and cyc-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube; atracurium; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00009137 bath-39 Enriched in germ line and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; mianserin; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00009138 F25H9.6 Predicted to enable FMN binding activity and phosphopantothenoylcysteine decarboxylase activity. Predicted to be involved in coenzyme A biosynthetic process. Predicted to be part of phosphopantothenoylcysteine decarboxylase complex. Is an ortholog of human PPCDC (phosphopantothenoylcysteine decarboxylase). WB:WBGene00009139 F25H9.7 Predicted to be involved in mitochondrial respiratory chain complex II assembly and succinate metabolic process. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human SDHAF3 (succinate dehydrogenase complex assembly factor 3). WB:WBGene00009140 F26A3.1 Predicted to enable lipase activity. Predicted to be involved in lipid storage. Predicted to be located in lipid droplet. Is an ortholog of human LDAH (lipid droplet associated hydrolase). WB:WBGene00009141 ncbp-2 Predicted to enable RNA cap binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nuclear envelope and nuclear periphery. Expressed in germ cell. Is an ortholog of human NCBP2 (nuclear cap binding protein subunit 2). WB:WBGene00009142 F26A3.4 Predicted to enable protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in dephosphorylation. Located in striated muscle dense body. Expressed in neurons. Is an ortholog of human DUSP28 (dual specificity phosphatase 28). WB:WBGene00009143 F26A3.5 Expressed in intestine. WB:WBGene00009144 del-3 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Expressed in neurons. WB:WBGene00009145 F26A3.7 Expressed in spermatheca. Is predicted to encode a protein with the following domains: GPALPP motifs-containing protein 1-like; Domain of unknown function DUF3752; and Protein of unknown function (DUF3752). Is an ortholog of human GPALPP1 (GPALPP motifs containing 1). WB:WBGene00009146 F26C11.1 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00009147 F26C11.3 Predicted to be located in extracellular region. Expressed in coelomocyte and intestine. WB:WBGene00009148 F26D2.3 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00009149 F26D2.10 Predicted to be located in membrane. WB:WBGene00009150 clec-234 Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Testosterone; and fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00009151 F26D2.13 Enriched in AFD; pharyngeal cell; and rect_D based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including let-60; clk-1; and isp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Zidovudine; and cadmium based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00009152 F26D2.14 Enriched in AFDL; AFDR; NSM; g1P; and rect_D based on tiling array and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Tunicamycin; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00009153 F26D2.15 Enriched in several structures, including AFD; I5 neuron; germ line; head mesodermal cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Human HSD17B14 enables estradiol 17-beta-dehydrogenase [NAD(P)] activity; identical protein binding activity; and testosterone 17-beta-dehydrogenase (NADP+) activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and Enoyl-(Acyl carrier protein) reductase. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00009154 F26D2.16 Enriched in ABplpappaa; MSpaapaa; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including sodium arsenite; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00009155 lhfp-4 Predicted to be involved in sensory perception of sound. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 67. Is an ortholog of human LHFPL4 (LHFPL tetraspan subfamily member 4). WB:WBGene00009156 clec-196 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in aspergillosis and chronic mucocutaneous candidiasis. Is an ortholog of human CLEC7A (C-type lectin domain containing 7A). WB:WBGene00009157 F26E4.2 Predicted to be located in membrane. WB:WBGene00009158 F26E4.3 Predicted to enable cysteine-type peptidase activity. Predicted to be an extracellular matrix structural constituent. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. Is an ortholog of human TINAGL1 (tubulointerstitial nephritis antigen like 1). WB:WBGene00009159 F26E4.4 Predicted to enable DNA binding activity. Predicted to be involved in tRNA transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. WB:WBGene00009160 F26E4.5 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. WB:WBGene00009161 cox-7C Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human COX7C (cytochrome c oxidase subunit 7C). WB:WBGene00009162 F26E4.7 Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell adhesion and extracellular matrix organization. Predicted to be located in extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in several diseases, including abdominal aortic aneurysm; corneal dystrophy (multiple); and degenerative disc disease. Is an ortholog of human POSTN (periostin) and TGFBI (transforming growth factor beta induced). WB:WBGene00009163 drsh-1 Enables ribonuclease III activity. Involved in primary miRNA processing and sexual reproduction. Predicted to be located in nucleus. Predicted to be part of microprocessor complex. Is an ortholog of human DROSHA (drosha ribonuclease III). WB:WBGene00009164 hrdl-1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in endoplasmic reticulum unfolded protein response and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and endoplasmic reticulum. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human AMFR (autocrine motility factor receptor). WB:WBGene00009165 gpx-1 Enables phospholipid-hydroperoxide glutathione peroxidase activity. Involved in cellular response to reactive oxygen species and regulation of peptide transport. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple) and spondylometaphyseal dysplasia Sedaghatian type. Is an ortholog of human GPX4 (glutathione peroxidase 4). WB:WBGene00009166 F26F2.1 Involved in innate immune response. WB:WBGene00009167 F26F2.2 Is affected by several genes including lin-35; nhr-49; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Mercuric Chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00009168 F26F2.3 Enriched in ABplapppapp; ABprapppapp; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including nanoparticle; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00009169 F26F2.4 Enriched in intestine and neurons based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00009170 F26F2.5 Enriched in ABplpppppp; ABprpppppp; and ventral nerve cord based on tiling array and single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Mercuric Chloride; and sesamin based on microarray and RNA-seq studies. WB:WBGene00009171 clec-263 Enriched in male-specific anatomical entity based on microarray studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; C-type lectin-like/link domain superfamily; and PAN-3 domain. WB:WBGene00009172 F26F2.7 Predicted to be involved in positive regulation of cilium assembly. Predicted to be located in ciliary basal body. Is an ortholog of human TAPT1 (transmembrane anterior posterior transformation 1). WB:WBGene00009173 prom-1 Enriched in several structures, including AVG; RIM; command interneuron; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including mianserin; bisphenol S; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: F-box only protein 47. WB:WBGene00009174 F26H9.2 Predicted to enable actin binding activity. Predicted to be involved in actin cytoskeleton organization. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; developmental and epileptic encephalopathy 70; and multiple sclerosis. Is an ortholog of human PHACTR4 (phosphatase and actin regulator 4). WB:WBGene00009175 F26H9.3 No description available WB:WBGene00009176 nmat-2 Predicted to enable nicotinamide-nucleotide adenylyltransferase activity and nicotinate-nucleotide adenylyltransferase activity. Predicted to be involved in NAD biosynthetic process. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9 and spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis. Is an ortholog of human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1) and NMNAT3 (nicotinamide nucleotide adenylyltransferase 3). WB:WBGene00009177 F26H9.5 Predicted to enable O-phospho-L-serine:2-oxoglutarate aminotransferase activity and pyridoxal phosphate binding activity. Predicted to be involved in L-serine biosynthetic process. Predicted to be located in cytoplasm. Expressed in head and tail. Human ortholog(s) of this gene implicated in Neu-Laxova syndrome 2 and PSAT deficiency. Is an ortholog of human PSAT1 (phosphoserine aminotransferase 1). WB:WBGene00009178 uggt-2 Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Involved in IRE1-mediated unfolded protein response; regulation of embryonic development; and regulation of nematode larval development. Predicted to be located in endoplasmic reticulum. Is an ortholog of human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1) and UGGT2 (UDP-glucose glycoprotein glucosyltransferase 2). WB:WBGene00009179 kbp-3 Predicted to be involved in cell division. Located in kinetochore. Part of Ndc80 complex. WB:WBGene00009180 nurf-1 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and methylated histone binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NURF complex. Expressed in several structures, including head; pharyngeal-intestinal valve; pharynx; tail; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease and amyotrophic lateral sclerosis. Is an ortholog of human BPTF (bromodomain PHD finger transcription factor). WB:WBGene00009182 F26H11.4 Enriched in AVK; germ line; head mesodermal cell; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including aldicarb; Ethanol; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00009183 F27C8.2 Enriched in several structures, including CAN; GABAergic neurons; body wall muscle cell; excretory cell; and spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and rrf-3 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; D-glucose; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Acyl-CoA N-acyltransferase. WB:WBGene00009184 F27C8.3 Enriched in CAN; CANL; CANR; and excretory cell based on single-cell RNA-seq studies. Is affected by several genes including clk-1; aak-2; and hsp-6 based on tiling array; microarray; and RNA-seq studies. Is affected by cholesterol based on RNA-seq studies. WB:WBGene00009185 pei-1 Enriched in RIBL; RIBR; germ line; sensory neurons; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; methylmercuric chloride; and manganese chloride based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily; BTB/POZ domain; and Phosphorylation site. WB:WBGene00009186 trcs-1 Predicted to enable carboxylic ester hydrolase activity. Predicted to be located in membrane. Expressed in germ line. Is an ortholog of human AADACL3 (arylacetamide deacetylase like 3). WB:WBGene00009187 F27D4.1 Predicted to enable electron transfer activity and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Located in mitochondrion. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Is an ortholog of human ETFA (electron transfer flavoprotein subunit alpha). WB:WBGene00009188 lsy-22 Enables DNA-binding transcription factor binding activity. Expressed in several structures, including body wall musculature and pharyngeal muscle cell. WB:WBGene00009189 F27D4.4 Predicted to enable metal ion binding activity. Predicted to be involved in cytoplasmic translation. Predicted to be located in cytosol. Expressed in hypodermis and intestine. Is an ortholog of human ZC3H15 (zinc finger CCCH-type containing 15). WB:WBGene00009190 F27D4.6 Expressed in pharyngeal neurons. WB:WBGene00009191 F27D4.7 Predicted to be involved in protein transport and vesicle-mediated transport. Predicted to be located in membrane. Is an ortholog of human SFT2D1 (SFT2 domain containing 1) and SFT2D2 (SFT2 domain containing 2). WB:WBGene00009192 asah-2 Predicted to enable N-acylsphingosine amidohydrolase activity. Predicted to be involved in fatty acid metabolic process and sphingolipid metabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis; sphingolipidosis; and spinal muscular atrophy with progressive myoclonic epilepsy. Is an ortholog of human ASAH1 (N-acylsphingosine amidohydrolase 1). WB:WBGene00009193 F27E5.3 Predicted to be located in membrane. WB:WBGene00009194 F27E5.5 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00009195 hpo-33 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including eat-2; sir-2.1; and tph-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including tryptophan; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00009196 F28B1.2 Enriched in germ line and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00009197 F28B1.3 Enriched in pharynx and in male based on microarray and RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00009200 F28C1.1 Enriched in germ line; head mesodermal cell; neurons; and rectal epithelium based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; age-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including D-glucose; bisphenol S; and Linolenic Acids based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Alternative splicing regulator; Suppressor of white apricot; Suppressor of white apricot, N-terminal domain; and Phosphorylation site. Is an ortholog of human CLASRP (CLK4 associating serine/arginine rich protein). WB:WBGene00009201 F28C1.3 Enriched in body wall musculature; coelomocyte; head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine Rich repeat; Leucine-rich repeat domain superfamily; Leucine-rich repeat; and Phosphorylation site. Is an ortholog of human PPP1R37 (protein phosphatase 1 regulatory subunit 37). WB:WBGene00009202 aptf-4 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and regulation of cell population proliferation. Predicted to be located in nucleus. Expressed in head neurons and ventral nerve cord. WB:WBGene00009203 aptf-3 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and regulation of cell population proliferation. Predicted to be located in nucleus. Expressed in head neurons and intestine. WB:WBGene00009204 pigg-1 Predicted to enable CP2 mannose-ethanolamine phosphotransferase activity. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human PIGG (phosphatidylinositol glycan anchor biosynthesis class G). WB:WBGene00009205 F28C6.5 Enriched in several structures, including germline precursor cell; muscle cell; pharyngeal neurons; tail hypodermis; and touch receptor neurons based on tiling array; microarray; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by nine chemicals including Heme; glycine; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00009206 B0513.t1 Is affected by dpy-21 and etr-1 based on RNA-seq studies. WB:WBGene00009207 F28C6.8 Predicted to enable phosphatidylglycerophosphatase activity and protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in dephosphorylation and phospholipid biosynthetic process. Is an ortholog of human PTPMT1 (protein tyrosine phosphatase mitochondrial 1). WB:WBGene00009208 F28C6.9 Enriched in neurons and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; elt-2; and csr-1 based on RNA-seq and microarray studies. Is affected by stearic acid; sucrose; and Colistin based on RNA-seq and microarray studies. WB:WBGene00009209 F28C6.10 Enriched in several structures, including I5 neuron; cholinergic neurons; retrovesicular ganglion; tail precursor cell; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by nine chemicals including mianserin; multi-walled carbon nanotube; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00009210 F28C12.6 Is affected by rsr-2 based on tiling array studies. Is affected by resveratrol based on microarray studies. WB:WBGene00009211 wdr-46 Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleolus. Expressed in body wall musculature; germ line; head; hypodermis; and intestine. Is an ortholog of human WDR46 (WD repeat domain 46). WB:WBGene00009212 atz-1 Involved in multicellular organismal reproductive process; positive regulation of DNA replication; and positive regulation of organelle organization. Located in nucleus. WB:WBGene00009213 thn-1 Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in extracellular region. WB:WBGene00009214 thn-3 Enriched in GABAergic neurons and dopaminergic neurons based on tiling array and RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by five chemicals including fluoranthene; Quercetin; and copper sulfate based on microarray studies. WB:WBGene00009215 thn-2 Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Predicted to be located in extracellular region. WB:WBGene00009216 F28D1.6 Predicted to be located in membrane. WB:WBGene00009217 spe-45 Predicted to be located in membrane. WB:WBGene00009218 acs-20 Predicted to enable long-chain fatty acid transporter activity and long-chain fatty acid-CoA ligase activity. Predicted to be involved in triglyceride homeostasis. Located in intracellular membrane-bounded organelle. Expressed in anal depressor muscle; anal sphincter muscle; head; hyp7 syncytium; and seam cell. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human SLC27A1 (solute carrier family 27 member 1) and SLC27A4 (solute carrier family 27 member 4). WB:WBGene00009219 dpm-3 Predicted to be involved in protein glycosylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of dolichol-phosphate-mannose synthase complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type I and muscular dystrophy-dystroglycanopathy type B15. Is an ortholog of human DPM3 (dolichyl-phosphate mannosyltransferase subunit 3, regulatory). WB:WBGene00009220 F28D9.4 Predicted to be located in mitochondrial inner membrane. WB:WBGene00009221 acs-2 Predicted to enable medium-chain fatty acid-CoA ligase activity. Involved in fatty acid metabolic process. Located in mitochondrion. Expressed in body wall musculature; hypodermis; intestine; neurons; and pharynx. Is an ortholog of human ACSF2 (acyl-CoA synthetase family member 2). WB:WBGene00009222 fbxa-95 Enriched in several structures, including Y cell; cholinergic neurons; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by six chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box A protein FB224; F-box-like domain superfamily; and F-box domain. WB:WBGene00009223 mdt-28 Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including gonad; hypodermis; and intestine. WB:WBGene00009224 F28F8.7 Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of histone deacetylase complex and transcription regulator complex. WB:WBGene00009225 fbxa-94 Enriched in several structures, including I5 neuron; cholinergic neurons; germline precursor cell; head mesodermal cell; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and elt-2 based on microarray and RNA-seq studies. Is affected by four chemicals including bortezomib; resveratrol; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00009226 cyp-37B1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in membrane. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Is an ortholog of human CYP4V2 (cytochrome P450 family 4 subfamily V member 2). WB:WBGene00009227 F28G4.2 Predicted to enable transferase activity. Predicted to be located in membrane. WB:WBGene00009228 F28G4.3 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; dpy-21; and smg-2 based on microarray and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Colistin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1647); Nucleotide-diphospho-sugar transferases; and Protein of unknown function DUF1647. WB:WBGene00009229 F28G4.4 Predicted to enable transferase activity. Predicted to be located in membrane. WB:WBGene00009230 oac-18 Enriched in NSM; intestine; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and alg-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00009231 ceh-89 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in neurons. Is an ortholog of human HOPX (HOP homeobox). WB:WBGene00009232 nkat-1 Predicted to enable kynurenine-oxoglutarate transaminase activity. Predicted to be involved in L-kynurenine metabolic process and biosynthetic process. Predicted to be located in mitochondrion. Expressed in RID; RIML; RIMR; RMDVL; and RMDVR. Is an ortholog of human KYAT1 (kynurenine aminotransferase 1). WB:WBGene00009233 F28H6.4 Enriched in several structures, including ABalppppppp; OLL; RIM; germ line; and interneuron based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by eight chemicals including D-glucose; stavudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545); Homeobox-like domain superfamily; SPK domain; and Phosphorylation site. WB:WBGene00009234 F28H6.6 Enriched in ASER; OLL; PVD; rect_D; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by six chemicals including aldicarb; Zidovudine; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00009235 F28H6.7 Enriched in CEM; HOB; IL2 neuron; neurons; and ray neuron type B based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on tiling array and microarray studies. Is affected by allantoin and Sirolimus based on microarray studies. WB:WBGene00009236 F28H7.2 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00009237 F28H7.3 Predicted to be involved in lipid metabolic process. WB:WBGene00009238 selt-1.2 Predicted to enable thioredoxin-disulfide reductase (NADP) activity. Predicted to be involved in cell redox homeostasis. Predicted to be located in endoplasmic reticulum membrane. Expressed in AWBL and AWBR. Is an ortholog of human SELENOT (selenoprotein T). WB:WBGene00009239 irld-6 Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. WB:WBGene00009240 F28H7.7 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00009241 F28H7.8 Enriched in PLM; dopaminergic neurons; hypodermis; and interfacial epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain superfamily; CRAL-TRIO lipid binding domain superfamily; and CRAL/TRIO domain. WB:WBGene00009242 sre-6 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00009243 F29C6.1 Enriched in several structures, including PLM; SIB; germ line; germline precursor cell; and pharyngeal muscle cell based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00009245 rict-1 Predicted to enable protein serine/threonine kinase activator activity. Involved in mesendoderm development. Part of TORC2 complex. Expressed in several structures, including head neurons; intestine; pharynx; spermatheca; and ventral nerve cord. Human ortholog(s) of this gene implicated in breast ductal carcinoma; gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of human RICTOR (RPTOR independent companion of MTOR complex 2). WB:WBGene00009246 gfm-1 Predicted to enable GTPase activity and translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 1. Is an ortholog of human GFM1 (G elongation factor mitochondrial 1). WB:WBGene00009247 bath-45 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including aldicarb; hydrogen sulfide; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00009248 F29C12.6 Enriched in M cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and daf-18 based on microarray and RNA-seq studies. Is affected by five chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009249 F29C12.7 Is affected by several genes including daf-16; fbf-1; and nuo-6 based on RNA-seq and microarray studies. Is affected by Cry5B based on microarray studies. WB:WBGene00009250 F29D10.1 Predicted to be located in membrane. WB:WBGene00009251 F29D10.2 Enriched in AVK based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00009252 F29D10.3 Is affected by several genes including sir-2.1; alg-1; and mex-3 based on proteomic; microarray; and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; resveratrol; and Colistin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; and PAN-3 domain. WB:WBGene00009254 capg-1 Involved in embryo development; meiotic sister chromatid segregation; and mitotic sister chromatid segregation. Part of dosage compensation complex. WB:WBGene00009255 ugt-34 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00009256 tut-2 Predicted to enable sulfurtransferase activity. Predicted to be involved in tRNA wobble position uridine thiolation. Predicted to be located in cytosol. Is an ortholog of human CTU2 (cytosolic thiouridylase subunit 2). WB:WBGene00009257 F29G6.1 Predicted to be involved in cell differentiation. WB:WBGene00009258 ccdc-149 Located in ciliary base. Expressed in neurons. Is an ortholog of human CCDC149 (coiled-coil domain containing 149). WB:WBGene00009259 hpo-34 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00009260 calm-1 Predicted to enable calcium ion binding activity and magnesium ion binding activity. Predicted to be involved in calcium ion homeostasis. Expressed in cholinergic neurons and ventral nerve cord. Human ortholog(s) of this gene implicated in Usher syndrome type 1J and autosomal recessive nonsyndromic deafness 48. Is an ortholog of human CIB2 (calcium and integrin binding family member 2) and CIB3 (calcium and integrin binding family member 3). WB:WBGene00009261 F30A10.2 Enriched in several structures, including germline precursor cell; intestine; sensory neurons; somatic gonad precursor; and tail hypodermis based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq; tiling array; and microarray studies. Is affected by twenty-one chemicals including methylmercury hydroxide; 1-methylnicotinamide; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009262 F30A10.3 Predicted to enable inositol hexakisphosphate kinase activity. Predicted to be involved in inositol phosphate biosynthetic process and phosphatidylinositol phosphate biosynthetic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human IP6K1 (inositol hexakisphosphate kinase 1); IP6K2 (inositol hexakisphosphate kinase 2); and IP6K3 (inositol hexakisphosphate kinase 3). WB:WBGene00009263 F30A10.4 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00009264 sacm-1L Predicted to enable phosphatidylinositol-4-phosphate phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be located in endoplasmic reticulum. Expressed in intestine; pharyngeal neurons; pharynx; spermatheca; and tail. Is an ortholog of human SACM1L (SAC1 like phosphatidylinositide phosphatase). WB:WBGene00009265 F30A10.7 No description available WB:WBGene00009266 F30A10.9 Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human FCF1 (FCF1 rRNA-processing protein). WB:WBGene00009267 usp-48 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in proteolysis. Predicted to be located in cytosol and nucleus. Expressed widely. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness. Is an ortholog of human USP48 (ubiquitin specific peptidase 48). WB:WBGene00009268 F30A10.11 Enriched in NSM; OLQ; intestinal muscle; rectal muscle; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00009269 F30A10.12 Predicted to be located in membrane. WB:WBGene00009270 F30F8.1 Enriched in several structures, including I5 neuron; RMD; cholinergic neurons; germ line; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including manganese chloride; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00009271 glna-3 Predicted to enable glutaminase activity. Predicted to be involved in glutamate biosynthetic process and glutamine catabolic process. Expressed in AWBL; AWBR; and head neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 71 and lymphangioleiomyomatosis. Is an ortholog of human GLS (glutaminase). WB:WBGene00009272 gras-1 Expressed in oocyte. Is predicted to encode a protein with the following domains: PDZ domain 6; PDZ superfamily; PDZ domain; and Phosphorylation site. Is an ortholog of human CYTIP (cytohesin 1 interacting protein) and TAMALIN (trafficking regulator and scaffold protein tamalin). WB:WBGene00009273 F30F8.4 No description available WB:WBGene00009274 F30F8.5 Enriched in several structures, including ABarpapaapp; ABarppaapp; ABarpppapp; ABplaaaaapp; and neurons based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including age-1; dpy-10; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; mianserin; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009276 F30F8.9 Predicted to enable ribosome binding activity. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); and uterine cancer. Is an ortholog of human LETMD1 (LETM1 domain containing 1). WB:WBGene00009277 F30F8.10 Predicted to enable histone acetyltransferase activity and peptide alpha-N-acetyltransferase activity. Predicted to be involved in chromatin remodeling and chromosome segregation. Predicted to be located in Golgi membrane. Is an ortholog of human NAA60 (N-alpha-acetyltransferase 60, NatF catalytic subunit). WB:WBGene00009278 npr-33 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including AGTR1 (angiotensin II receptor type 1); AGTR2 (angiotensin II receptor type 2); and APLNR (apelin receptor). WB:WBGene00009279 F31B9.2 Enriched in B cell based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and hsp-6 based on RNA-seq and microarray studies. Is affected by antimycin and glycine based on RNA-seq studies. WB:WBGene00009280 F31B9.3 Enriched in several structures, including cephalic sheath cell; cholinergic neurons; germ line; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; rrf-3; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009281 F31B9.4 Enriched in Y cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and nhr-49 based on microarray; tiling array; and RNA-seq studies. Is affected by Tunicamycin; antimycin; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00009283 F31B12.4 Enriched in several structures, including ABalaapppa; ABalaappppa; ABalapaaaa; ABalapaapa; and neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including daf-2; pgl-1; and mex-3 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00009284 gldr-2 Predicted to be involved in mRNA polyadenylation. WB:WBGene00009285 fmp-27 Enriched in body wall musculature; germ line; somatic nervous system; and vulval muscle based on Chronogram; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; Alovudine; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Hobbit; FMP27, sixth RBG unit; Golgi-body localisation protein domain; RNA pol II promoter Fmp27 protein domain; FMP27/BLTP2/Hobbit, GFWDK motif-containing RBG unit; BLTP2/FMP27/Hobbit, C-terminal; Domain of unknown function (DUF2405); and Phosphorylation site. Is an ortholog of human BLTP2 (bridge-like lipid transfer protein family member 2). WB:WBGene00009286 zipt-1 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human SLC39A1 (solute carrier family 39 member 1). WB:WBGene00009287 psf-2 Predicted to be involved in double-strand break repair via break-induced replication. Predicted to be located in nuclear chromosome. Predicted to be part of GINS complex. Is an ortholog of human GINS2 (GINS complex subunit 2). WB:WBGene00009288 F31C3.6 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cell cortex. WB:WBGene00009289 exos-7 Predicted to be involved in RNA metabolic process. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Expressed in motor neurons. Is an ortholog of human EXOSC7 (exosome component 7). WB:WBGene00009290 F31D4.2 Predicted to enable phosphatase activity. Predicted to be involved in methylation. Expressed widely. Is an ortholog of human ARMT1 (acidic residue methyltransferase 1). WB:WBGene00009291 clec-264 Involved in defense response to Gram-positive bacterium. WB:WBGene00009292 F31D4.5 Enriched in several structures, including NSM; intestine; sensory neurons; tail hypodermis; and ventral cord blast cell based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PH-like domain superfamily; Pleckstrin homology domain; and PH domain. Is an ortholog of human PLEKHD1 (pleckstrin homology and coiled-coil domain containing D1). WB:WBGene00009293 F31D4.8 Enriched in several structures, including ABalpppappp; ABarpapaapp; anterior arcade cell; g1; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00009294 ndua-1 Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. WB:WBGene00009295 fbxa-180 Enriched in OLL; PVD; and intestine based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; manganese chloride; and D-glucopyranose based on RNA-seq and microarray studies. WB:WBGene00009296 F31E9.3 Enriched in coelomocyte; intestine; neurons; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00009297 sdz-16 Enriched in g1; hypodermis; interneuron; and muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00009298 srz-58 Predicted to be located in membrane. WB:WBGene00009299 F31E9.6 Enriched in several structures, including G2; PVR; W cell; body wall muscle cell; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including rotenone; mianserin; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00009300 F31F6.1 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00009301 F31F6.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including hydrogen sulfide; rotenone; and bisphenol A based on microarray and RNA-seq studies. WB:WBGene00009302 F31F6.3 Enriched in AVE and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; bisphenol A; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00009303 lips-8 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00009304 eva-1 Predicted to enable carbohydrate binding activity. Located in M band; cell junction; and striated muscle dense body. Expressed in body wall musculature; hypodermis; pharyngeal muscle cell; and ventral nerve cord. Is an ortholog of human EVA1C (eva-1 homolog C). WB:WBGene00009305 metl-17 Predicted to be a structural constituent of ribosome. Predicted to be involved in methylation and translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human METTL17 (methyltransferase like 17). WB:WBGene00009306 maph-1.1 Predicted to enable actin binding activity and microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization; neuron projection development; and regulation of microtubule depolymerization. Located in microtubule cytoskeleton. Expressed in body wall musculature; egg-laying apparatus; hypodermis; intestinal cell; and neurons. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness and periventricular nodular heterotopia. Is an ortholog of human MAP1A (microtubule associated protein 1A); MAP1B (microtubule associated protein 1B); and MAP1S (microtubule associated protein 1S). WB:WBGene00009307 F32A11.1 Predicted to be located in extracellular space. Is an ortholog of human C3orf33 (chromosome 3 open reading frame 33). WB:WBGene00009308 spe-18 Expressed in spermatocyte. WB:WBGene00009309 F32A11.4 Is affected by several genes including daf-16; clk-1; and alg-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00009310 F32A11.5 Expressed in neurons. WB:WBGene00009311 mltn-1 Predicted to be located in membrane. WB:WBGene00009312 F32B4.1 Predicted to be located in membrane. WB:WBGene00009313 F32B4.2 Predicted to enable mitochondrion targeting sequence binding activity. Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix and tRNA import into mitochondrion. Predicted to be located in mitochondrial outer membrane. Predicted to be part of mitochondrial outer membrane translocase complex. Is an ortholog of human TOMM20L (translocase of outer mitochondrial membrane 20 like). WB:WBGene00009314 phm-2 Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of mRNA processing and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including body wall musculature; intestine; pharynx; somatic nervous system; and vulva. WB:WBGene00009315 F32B4.5 Enriched in head mesodermal cell and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including aak-2; isp-1; and unc-30 based on RNA-seq studies. Is affected by nine chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. Human KCTD12 enables identical protein binding activity. Is an ortholog of human KCTD12 (potassium channel tetramerization domain containing 12); KCTD16 (potassium channel tetramerization domain containing 16); and KCTD8 (potassium channel tetramerization domain containing 8). WB:WBGene00009316 abhd-11.1 Predicted to enable carboxylic ester hydrolase activity. Predicted to be involved in cellular lipid metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human ABHD11 (abhydrolase domain containing 11). WB:WBGene00009318 F32B4.8 Enriched in anterior ganglion (ant); arc ant V; excretory system; and hyp3 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercury hydroxide; manganese chloride; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00009319 mccc-1 Predicted to enable ATP binding activity and ligase activity. Predicted to contribute to methylcrotonoyl-CoA carboxylase activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in 3-Methylcrotonyl-CoA carboxylase 1 deficiency. Is an ortholog of human MCCC1 (methylcrotonyl-CoA carboxylase subunit 1). WB:WBGene00009320 prp-18 Predicted to be involved in generation of catalytic spliceosome for second transesterification step. Predicted to be located in nuclear speck. Predicted to be part of U2-type post-spliceosomal complex; U4/U6 x U5 tri-snRNP complex; and U5 snRNP. Is an ortholog of human PRPF18 (pre-mRNA processing factor 18). WB:WBGene00009321 F32B6.4 Enriched in AIAL; AIAR; germ line; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-eight chemicals including Heme; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00009322 tbc-3 Predicted to enable GTPase activator activity. Located in Golgi apparatus. Expressed in hermaphrodite distal tip cell; neurons; pharynx; rect_D; and seam cell. Is an ortholog of human TBC1D22A (TBC1 domain family member 22A) and TBC1D22B (TBC1 domain family member 22B). WB:WBGene00009323 best-13 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Expressed in vulB1; vulB2; vulC; vulD; and vulE. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00009324 ttbk-3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Expressed in neurons. WB:WBGene00009325 F32D8.15 Predicted to be located in membrane. Expressed in head neurons; motor neurons; and tail neurons. Is an ortholog of human INAFM2 (InaF motif containing 2). WB:WBGene00009326 F32D8.1 Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00009327 F32D8.2 Predicted to be located in membrane. WB:WBGene00009328 F32D8.3 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00009329 F32D8.4 Predicted to be involved in box C/D snoRNP assembly and rRNA processing. Predicted to be located in cytoplasm. Predicted to be part of R2TP complex and ribonucleoprotein complex. Is an ortholog of human PIH1D1 (PIH1 domain containing 1). WB:WBGene00009330 F32D8.5 Predicted to be involved in mitochondrial proton-transporting ATP synthase complex assembly. Predicted to be located in membrane and mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 2. Is an ortholog of human TMEM70 (transmembrane protein 70). WB:WBGene00009331 F32D8.7 Predicted to enable serine-type endopeptidase inhibitor activity. Involved in PERK-mediated unfolded protein response. Predicted to be located in membrane. WB:WBGene00009332 F32D8.8 Predicted to be located in membrane. WB:WBGene00009333 zzz-1 Predicted to be located in membrane. WB:WBGene00009334 F32D8.12 Predicted to enable D-lactate dehydrogenase (cytochrome) activity; D-lactate dehydrogenase activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in lactate catabolic process. Predicted to be located in mitochondrion. Is an ortholog of human LDHD (lactate dehydrogenase D). WB:WBGene00009335 F32D8.13 Predicted to enable phosphomevalonate kinase activity. Predicted to be involved in cholesterol biosynthetic process and isopentenyl diphosphate biosynthetic process, mevalonate pathway. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in porokeratosis. Is an ortholog of human PMVK (phosphomevalonate kinase). WB:WBGene00009336 F32D8.14 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and vesicle fusion with Golgi apparatus. Predicted to be located in trans-Golgi network. Is an ortholog of human YIPF7 (Yip1 domain family member 7). WB:WBGene00009337 uig-1 Enables protein domain specific binding activity. Involved in regulation of engulfment of apoptotic cell. Located in striated muscle dense body. Expressed in OLL; non-striated muscle; tail; and vulva. Is an ortholog of human PLEKHG1 (pleckstrin homology and RhoGEF domain containing G1). WB:WBGene00009338 F32G8.2 Predicted to be located in membrane. WB:WBGene00009339 F32G8.3 Involved in defense response to Gram-negative bacterium. WB:WBGene00009340 best-14 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00009341 thoc-3 Predicted to be involved in mRNA export from nucleus. Predicted to be part of THO complex part of transcription export complex. Is an ortholog of human THOC3 (THO complex subunit 3). WB:WBGene00009342 fasn-1 Predicted to enable fatty acid synthase activity. Predicted to be involved in fatty acid biosynthetic process. Expressed in excretory duct; hermaphrodite gonad; hypodermis; intestine; and neurons. Used to study muscular disease. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human FASN (fatty acid synthase). WB:WBGene00009343 F32H2.6 Predicted to enable acyltransferase activity. WB:WBGene00009344 F32H2.7 Enriched in I5 neuron; germ line; mechanosensory neurons; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-eight chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009345 F32H2.8 Predicted to be located in membrane. WB:WBGene00009346 F32H2.10 Enriched in several structures, including ABplpppaaa; AFD; Caapa; NSM; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Armadillo-type fold. WB:WBGene00009347 F32H5.1 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). WB:WBGene00009349 F32H5.3 Enriched in several structures, including AFD; Caaaaa; Caaaap; Caaapa; and RIV based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including Heme; hydrogen sulfide; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009350 F32H5.4 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00009352 F33A8.4 Predicted to enable rRNA (adenine-N6-)-methyltransferase activity. Predicted to be involved in rRNA methylation. Predicted to be located in cytoplasm and nucleolus. Is an ortholog of human ZCCHC4 (zinc finger CCHC-type containing 4). WB:WBGene00009353 sdhd-1 Predicted to enable heme binding activity and ubiquinone binding activity. Predicted to contribute to succinate dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone and tricarboxylic acid cycle. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone). Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; mitochondrial complex II deficiency; and paraganglioma. Is an ortholog of human SDHD (succinate dehydrogenase complex subunit D). WB:WBGene00009354 ilkp-1 Predicted to enable metal ion binding activity and protein serine/threonine phosphatase activity. Is an ortholog of human ILKAP (ILK associated serine/threonine phosphatase). WB:WBGene00009355 F33A8.7 Enriched in several structures, including ABalpppppa; anterior hypodermis; head ganglion; interfacial epithelial cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including methylmercury hydroxide; 1-methylnicotinamide; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00009356 srlf-15 Enriched in anterior hypodermis; interfacial epithelial cell; pharyngeal muscle cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00009357 F33C8.2 Enriched in AFD; neurons; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00009358 F33C8.4 Enriched in head mesodermal cell; muscle cell; and neurons based on tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on proteomic; RNA-seq; and microarray studies. Is affected by fourteen chemicals including methylmercuric chloride; rotenone; and D-glucopyranose based on microarray and RNA-seq studies. WB:WBGene00009359 clec-102 Enriched in MSpaaaaa and body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-12; pgl-1; and glh-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; C-type lectin fold; and PAN-3 domain. WB:WBGene00009360 F33E2.4 Enriched in AVK and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00009361 F33E2.5 Enriched in several structures, including ABalppppaa; amphid neurons; germ line; intestinal muscle; and rectal muscle based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00009362 F33E2.6 Enriched in NSM; sensory neurons; and in male based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and mex-1 based on microarray and RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009363 F33E2.7 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00009364 wbp-11 Predicted to be involved in RNA processing. Is an ortholog of human WBP11 (WW domain binding protein 11). WB:WBGene00009365 F33H1.4 Predicted to be located in nucleolus. Expressed in gonad. WB:WBGene00009366 F33H2.2 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABprpaaapa; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and npr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: FAM91; FAM91 C-terminus; FAM91 N-terminus; FAM91, N-terminal domain; FAM91, C-terminal domain; and Phosphorylation site. Is an ortholog of human FAM91A1 (family with sequence similarity 91 member A1). WB:WBGene00009367 F33H2.3 Predicted to enable histone binding activity. Predicted to be located in nucleus. Is an ortholog of human ANP32A (acidic nuclear phosphoprotein 32 family member A); ANP32B (acidic nuclear phosphoprotein 32 family member B); and ANP32CP (acidic nuclear phosphoprotein 32 family member C, pseudogene). WB:WBGene00009368 pole-1 Predicted to enable DNA binding activity; DNA-directed DNA polymerase activity; and single-stranded DNA 3'-5' DNA exonuclease activity. Predicted to be involved in DNA metabolic process and mitotic cell cycle. Predicted to be located in nucleus. Predicted to be part of epsilon DNA polymerase complex. Human ortholog(s) of this gene implicated in ascending colon cancer; carcinoma (multiple); and mismatch repair cancer syndrome. Is an ortholog of human POLE (DNA polymerase epsilon, catalytic subunit). WB:WBGene00009369 F33H2.6 Predicted to enable microtubule binding activity. Predicted to be located in mitochondrion; mitotic spindle pole; and spindle microtubule. Is an ortholog of human RMDN1 (regulator of microtubule dynamics 1). WB:WBGene00009370 set-10 Predicted to enable metal ion binding activity. Predicted to be located in nucleus. Expressed in hypodermis. WB:WBGene00009371 F33H2.8 Predicted to be located in membrane. WB:WBGene00009372 evl-18 Predicted to enable DNA replication origin binding activity; chromatin binding activity; and single-stranded DNA binding activity. Predicted to be involved in DNA replication initiation; double-strand break repair via break-induced replication; and mitotic DNA replication preinitiation complex assembly. Located in nucleus. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 7. Is an ortholog of human CDC45 (cell division cycle 45). WB:WBGene00009373 F34D10.3 Predicted to be located in membrane. WB:WBGene00009374 F34D10.4 Enriched in IL socket cell; germ line; germline precursor cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; bisphenol S; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009375 arcp-1 Expressed in ciliated neurons. Is predicted to encode a protein with the following domains: Ankyrin repeats (3 copies); Dpy-30 motif; Ankyrin repeat-containing domain superfamily; and Ankyrin repeat. WB:WBGene00009377 F34D10.8 Enriched in germ line; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including hydrogen sulfide; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00009378 F34H10.1 Enriched in AVK and neurons based on RNA-seq studies. Is affected by several genes including eat-2; hda-1; and mep-1 based on microarray and RNA-seq studies. WB:WBGene00009380 F34H10.3 Enriched in accessory cell; rectal epithelium; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Cry5B; levamisole; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009381 F34H10.4 Expressed in head. WB:WBGene00009382 F34H10.5 Enriched in AWA based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00009383 idpp-16 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and mechanosensory neurons based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-six chemicals including rotenone; bisphenol A; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00009384 piit-1 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00009385 sas-5 Involved in centriole replication. Located in centriole and cytoplasm. WB:WBGene00009386 tag-290 Predicted to enable serine-type endopeptidase inhibitor activity. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); leukemia (multiple); and thrombophilia (multiple). Is an ortholog of human TFPI (tissue factor pathway inhibitor) and TFPI2 (tissue factor pathway inhibitor 2). WB:WBGene00009387 glb-15 Predicted to enable heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. WB:WBGene00009388 F35B12.9 Predicted to be located in membrane. WB:WBGene00009389 F35B12.10 Predicted to enable BMP binding activity and receptor ligand activity. Predicted to be involved in animal organ morphogenesis and sequestering of BMP from receptor via BMP binding activity. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in tooth agenesis. Is an ortholog of human GREM1 (gremlin 1, DAN family BMP antagonist). WB:WBGene00009390 F35C5.1 Enriched in AVA; germ line; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; manganese chloride; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00009391 F35C5.3 Enriched in neurons and in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and lin-4 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Trimeric LpxA-like superfamily. WB:WBGene00009392 F35C5.4 Enriched in neurons based on RNA-seq studies. Is affected by clk-1; spt-16; and daf-2 based on microarray and RNA-seq studies. Is affected by resveratrol and tetrabromobisphenol A based on microarray studies. WB:WBGene00009393 clec-62 Involved in innate immune response. WB:WBGene00009394 clec-63 Expressed in germ line and intestine. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; C-type lectin-like; von Willebrand factor A-like domain superfamily; C-type lectin-like/link domain superfamily; Lectin C-type domain; and C-type lectin fold. WB:WBGene00009395 clec-64 Expressed in head neurons and in male. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; C-type lectin-like; von Willebrand factor A-like domain superfamily; C-type lectin-like/link domain superfamily; and C-type lectin fold. WB:WBGene00009396 clec-65 Expressed in intestine. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; C-type lectin-like; von Willebrand factor A-like domain superfamily; C-type lectin-like/link domain superfamily; Lectin C-type domain; and C-type lectin fold. WB:WBGene00009397 clec-66 Involved in innate immune response. Expressed in intestine. WB:WBGene00009398 nspb-11 Enriched in MC neuron; interfacial epithelial cell; rectal gland cell; and touch receptor neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; rotenone; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00009399 ddn-2 Predicted to be located in membrane. Expressed in amphid neurons; inner labial neurons; and intestine. WB:WBGene00009400 F35C5.12 Predicted to be involved in defense response. Predicted to be located in extracellular region. WB:WBGene00009401 F35C11.2 Predicted to enable protein tyrosine phosphatase activity. Human ortholog(s) of this gene implicated in multiple sclerosis and severe combined immunodeficiency. Is an ortholog of human PTPRC (protein tyrosine phosphatase receptor type C). WB:WBGene00009402 F35C11.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00009403 F35C11.4 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. Is an ortholog of human PGAP4 (post-GPI attachment to proteins GalNAc transferase 4). WB:WBGene00009404 F35C11.5 Predicted to enable phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion and phospholipid metabolic process. Predicted to be located in extracellular region and membrane. WB:WBGene00009405 F35C11.6 Enriched in AFD; MSpaapaa; PLM; hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009406 F35C11.7 Enriched in accessory cell; mechanosensory neurons; and pm8 based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; aak-2; and unc-30 based on microarray and RNA-seq studies. Is affected by eight chemicals including D-glucose; Cry5B; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; Thrombospondin type 1 domain; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00009408 F35C12.3 Enriched in coelomocyte; hypodermis; and male-specific anatomical entity based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; glp-1; and let-60 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00009409 F35E2.1 Predicted to be located in membrane. WB:WBGene00009410 F35E2.2 Enriched in DD neuron based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including methylmercuric chloride; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00009411 F35E2.3 Enriched in FLP; germ line; and in male based on microarray and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; cholesterol; and paraquat based on microarray and RNA-seq studies. WB:WBGene00009412 F35E2.5 Enriched in germ line; muscle cell; and in male based on RNA-seq studies. Is affected by several genes including daf-2; pie-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; rotenone; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Nematode trypsin-6-like family and Chymotrypsin family Peptidase-S1. WB:WBGene00009413 oac-19 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00009414 F35E2.7 Enriched in male based on RNA-seq studies. Is affected by several genes including let-60; lin-4; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00009415 F35E2.8 Enriched in K cell and K' cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00009416 F35E2.9 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00009417 F35E8.1 Predicted to be located in membrane. WB:WBGene00009418 F35E8.2 Enriched in MSaaaaapa; MSaapaapa; MSpapaapa; and g1 based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including Mercuric Chloride; antimycin; and fluvastatin based on microarray and RNA-seq studies. WB:WBGene00009419 F35E8.4 Is affected by several genes including daf-2; eat-2; and lin-35 based on microarray and RNA-seq studies. WB:WBGene00009420 F35E8.6 Is affected by several genes including daf-16; daf-2; and clk-1 based on microarray and RNA-seq studies. Is affected by resveratrol and dafa#1 based on microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00009421 F35E8.7 Is affected by several genes including daf-2; daf-12; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by cadmium and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00009422 F35E8.9 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Acrylamide; Chlorpyrifos; and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00009423 F35E8.10 Enriched in MSaaaaapa based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Tunicamycin; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00009424 F35E8.13 Enriched in DA neuron; VA neuron; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sek-1 based on microarray; RNA-seq; and tiling array studies. Is affected by four chemicals including Rifampin; mianserin; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00009425 scl-16 Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00009426 F35E12.2 Predicted to be involved in innate immune response. Predicted to be located in membrane. WB:WBGene00009427 fbxa-181 Enriched in germ line based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; methylmercury hydroxide; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00009428 F35E12.4 Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including 1-methylnicotinamide; rotenone; and indole based on RNA-seq and microarray studies. WB:WBGene00009429 irg-5 Involved in defense response to Gram-positive bacterium. WB:WBGene00009430 F35E12.6 Involved in innate immune response. WB:WBGene00009431 dct-17 Involved in defense response to Gram-negative bacterium and innate immune response. Located in membrane raft. WB:WBGene00009432 cld-9 Involved in innate immune response. WB:WBGene00009433 F35E12.9 Predicted to be involved in innate immune response. WB:WBGene00009434 F35E12.10 Predicted to be involved in innate immune response. Located in membrane raft. WB:WBGene00009435 F35G2.1 Predicted to enable flavin-dependent sulfhydryl oxidase activity and protein disulfide isomerase activity. Predicted to be involved in protein folding. Predicted to be located in extracellular space. Is an ortholog of human QSOX1 (quiescin sulfhydryl oxidase 1) and QSOX2 (quiescin sulfhydryl oxidase 2). WB:WBGene00009436 marb-1 Predicted to be located in cytoplasm. Is an ortholog of human ISOC2 (isochorismatase domain containing 2). WB:WBGene00009437 F35G2.3 Predicted to be located in membrane. WB:WBGene00009438 F35G2.5 Predicted to be located in membrane. WB:WBGene00009439 mlcd-1 Predicted to enable malonyl-CoA decarboxylase activity. Predicted to be involved in acetyl-CoA biosynthetic process; fatty acid biosynthetic process; and malonyl-CoA catabolic process. Predicted to be located in mitochondrial matrix and peroxisomal matrix. Human ortholog(s) of this gene implicated in cardiomyopathy. Is an ortholog of human MLYCD (malonyl-CoA decarboxylase). WB:WBGene00009440 idhg-1 Predicted to enable NAD binding activity and magnesium ion binding activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to be located in mitochondrion. Is an ortholog of human IDH3G (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma). WB:WBGene00009441 wdr-48 Predicted to enable ubiquitin binding activity. Involved in positive regulation of locomotion involved in locomotory behavior; positive regulation of macromolecule metabolic process; and positive regulation of protein localization to cell surface. Expressed in head neurons and tail. Is an ortholog of human WDR48 (WD repeat domain 48). WB:WBGene00009442 F35G12.5 Enriched in ABplpapppa; germ line; germline precursor cell; and pharyngeal cell based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by nine chemicals including manganese chloride; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00009443 F35G12.7 Predicted to enable copper ion binding activity. Predicted to be involved in response to metal ion. Is an ortholog of human CUTA (cutA divalent cation tolerance homolog). WB:WBGene00009444 erh-2 Involved in piRNA processing; positive regulation of cell division; and positive regulation of chromosome segregation. Located in nucleus and perinuclear region of cytoplasm. Is an ortholog of human ERH (ERH mRNA splicing and mitosis factor). WB:WBGene00009445 F35G12.12 Predicted to be involved in proteasome assembly. Predicted to be part of proteasome complex. Is an ortholog of human PSMD5 (proteasome 26S subunit, non-ATPase 5). WB:WBGene00009446 F35H8.1 Enriched in amphid sheath cell; germ line; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including D-glucose; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00009447 F35H8.2 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00009448 zfp-2 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in body wall musculature; hermaphrodite gonad; pharynx; seam cell; and vulva. Is an ortholog of human ZBTB32 (zinc finger and BTB domain containing 32). WB:WBGene00009449 F35H8.4 Predicted to be located in membrane. WB:WBGene00009450 ugt-58 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT2A2 (UDP glucuronosyltransferase family 2 member A2); UGT3A2 (UDP glycosyltransferase family 3 member A2); and UGT8 (UDP glycosyltransferase 8). WB:WBGene00009451 cids-2 Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Is an ortholog of human RPRD2 (regulation of nuclear pre-mRNA domain containing 2). WB:WBGene00009452 F36A2.2 Predicted to enable tRNA dihydrouridine synthase activity. Predicted to be involved in tRNA dihydrouridine synthesis. Is an ortholog of human DUS1L (dihydrouridine synthase 1 like). WB:WBGene00009453 F36A2.3 Predicted to enable oxidoreductase activity. WB:WBGene00009454 F36A2.7 Predicted to be located in membrane. Expressed in several structures, including pharynx and spermatheca. WB:WBGene00009455 phip-1 Predicted to enable protein histidine phosphatase activity. Predicted to be involved in cell differentiation and sex differentiation. Predicted to be located in cytosol. Expressed in pharyngeal motor neurons and ventral cord neurons. Is an ortholog of human PHPT1 (phosphohistidine phosphatase 1). WB:WBGene00009456 F36A2.9 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Predicted to be located in membrane. Is an ortholog of human PLB1 (phospholipase B1). WB:WBGene00009457 F36A2.10 Predicted to enable DNA binding activity. WB:WBGene00009458 F36A2.11 Enriched in germ line; hyp3; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily. WB:WBGene00009459 F36A2.12 Enriched in germ line; somatic gonad precursor; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009460 ubr-5 Predicted to enable ubiquitin-ubiquitin ligase activity. Predicted to be involved in positive regulation of canonical Wnt signaling pathway. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in carcinoma (multiple) and invasive ductal carcinoma. Is an ortholog of human UBR5 (ubiquitin protein ligase E3 component n-recognin 5). WB:WBGene00009461 madf-2 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. WB:WBGene00009462 sre-22 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in URBL; URBR; and body wall musculature. WB:WBGene00009463 F36D1.4 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including hydrogen sulfide; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00009464 F36D1.5 Enriched in DA neuron; VA neuron; body wall muscle cell; and hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00009465 F36D1.6 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pmk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Peptidase S1, PA clan; Nematode trypsin-6-like family; and Chymotrypsin family Peptidase-S1. WB:WBGene00009466 spex-2 Enriched in excretory system; intestine; and neurons based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including tryptophan; rotenone; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009467 F36D1.8 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00009468 F36D1.9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including rrf-3; pgl-1; and isp-1 based on microarray and RNA-seq studies. Is affected by rotenone and Doxycycline based on RNA-seq studies. WB:WBGene00009469 F36D3.1 Expressed in gonad. WB:WBGene00009470 F36D3.4 Predicted to be located in cytoskeleton. Expressed in spermatheca. WB:WBGene00009471 F36D3.5 Predicted to be located in membrane. WB:WBGene00009472 F36D3.7 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. Is affected by Rifampin and Psoralens based on RNA-seq studies. WB:WBGene00009473 F36D3.8 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including nicotinic acid; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; Domain of unknown function DUF1248; and Protein of unknown function (DUF1248). WB:WBGene00009474 clec-235 Is affected by lin-15B; drh-3; and eat-2 based on microarray and RNA-seq studies. Is affected by Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00009475 F36F2.1 Predicted to enable actin binding activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of transcription by RNA polymerase II. Located in endoplasmic reticulum. Is an ortholog of human ABRA (actin binding Rho activating protein). WB:WBGene00009476 F36F2.2 Enriched in OLQ; Psub1; dopaminergic neurons; head mesodermal cell; and muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including rotenone; Tunicamycin; and levamisole based on RNA-seq and microarray studies. WB:WBGene00009477 rbpl-1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Expressed in intestine; neurons; spermatheca; and vulva. Is an ortholog of human RBBP6 (RB binding protein 6, ubiquitin ligase). WB:WBGene00009478 syx-7 Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; vesicle docking; and vesicle fusion. Predicted to be located in synaptic vesicle. Predicted to be part of SNARE complex. Is an ortholog of human STX12 (syntaxin 12) and STX7 (syntaxin 7). WB:WBGene00009479 fcp-1 Enables RNA polymerase II CTD heptapeptide repeat phosphatase activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human CTDP1 (CTD phosphatase subunit 1). WB:WBGene00009480 F36F2.7 Predicted to be located in membrane. WB:WBGene00009481 F36F2.8 Enriched in several structures, including HSN; ciliated neurons; enteric muscle; g1P; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq studies. WB:WBGene00009482 F36G3.1 Enriched in several structures, including ABplppppaa; ABprppppaa; anterior hypodermis; mechanosensory neurons; and rect_D based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including levamisole; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009483 F36G3.2 Enriched in several structures, including PVW; head mesodermal cell; intestine; mechanosensory neurons; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Acyl-CoA N-acyltransferase. WB:WBGene00009484 F36G3.3 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1C. Is an ortholog of human LITAF (lipopolysaccharide induced TNF factor). WB:WBGene00009485 F36G9.3 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00009486 F36G9.7 Predicted to be located in membrane. WB:WBGene00009487 clec-232 Enriched in DA neuron; VA neuron; body wall muscle cell; neurons; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including D-glucose; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00009488 oac-20 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00009489 F36G9.13 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on RNA-seq; tiling array; and microarray studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function and Domain of unknown function WSN. WB:WBGene00009490 fbxa-99 Enriched in AIML; AIMR; g1AL; g1AR; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including age-1; let-60; and elt-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Heme; tryptophan; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00009491 F36G9.15 Predicted to be located in membrane. WB:WBGene00009492 F36H1.3 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00009493 hrg-4 Enables heme binding activity and heme transmembrane transporter activity. Involved in heme transport. Located in plasma membrane. WB:WBGene00009494 hrg-5 Predicted to enable heme binding activity and heme transmembrane transporter activity. Predicted to be involved in heme transport. Predicted to be located in lysosomal membrane and plasma membrane. WB:WBGene00009495 hrg-6 Predicted to enable heme binding activity and heme transmembrane transporter activity. Predicted to be involved in heme transport. Predicted to be located in lysosomal membrane and plasma membrane. WB:WBGene00009496 F36H1.11 Enriched in I5 neuron; ganglia; head neurons; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00009497 F36H1.12 Is affected by several genes including eat-2; hpl-2; and kri-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Tunicamycin and atracurium based on microarray and RNA-seq studies. WB:WBGene00009498 tat-5 Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Involved in embryo development and reproduction. Located in cytoplasmic vesicle and plasma membrane. Expressed widely. Is an ortholog of human ATP9B (ATPase phospholipid transporting 9B (putative)). WB:WBGene00009499 ent-6 Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in plasma membrane. WB:WBGene00009500 cfh-1 Enriched in anterior hypodermis; dopaminergic neurons; head neurons; interfacial epithelial cell; and intestine based on Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; D-glucose; and stavudine based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in malaria. Human CR1 enables complement receptor activity and opsonin binding activity. Is predicted to encode a protein with the following domains: Sushi repeat (SCR repeat); Sushi/SCR/CCP domain; and Sushi/SCR/CCP superfamily. Is an ortholog of human CR1 (complement C3b/C4b receptor 1 (Knops blood group)). WB:WBGene00009501 F37A8.1 Enriched in germ line; muscle cell; and in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00009502 F37A8.2 Enriched in AVK; germ line; and in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00009503 F37A8.5 Predicted to enable metal ion binding activity. Is an ortholog of human YPEL1 (yippee like 1) and YPEL2 (yippee like 2). WB:WBGene00009504 F37B12.1 Predicted to be located in membrane. WB:WBGene00009505 F37B12.3 Predicted to enable transferase activity, transferring alkyl or aryl (other than methyl) groups. Predicted to contribute to dehydrodolichyl diphosphate synthase activity. Predicted to be involved in dolichol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of dehydrodolichyl diphosphate synthase complex. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 55 and congenital disorder of glycosylation Iaa. Is an ortholog of human NUS1 (NUS1 dehydrodolichyl diphosphate synthase subunit). WB:WBGene00009507 mus-101 Involved in several processes, including DNA damage response; DNA-templated DNA replication; and germ cell proliferation. Is an ortholog of human TOPBP1 (DNA topoisomerase II binding protein 1). WB:WBGene00009508 row-1 Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of several human genes including ZNF280A (zinc finger protein 280A); ZNF280C (zinc finger protein 280C); and ZNF280D (zinc finger protein 280D). WB:WBGene00009509 F37D6.3 Predicted to enable RNA binding activity. WB:WBGene00009510 F37D6.4 Predicted to be located in membrane. WB:WBGene00009511 F37H8.2 Enriched in neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; rotenone; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00009512 bigr-1 Expressed in intestine and ventral nerve cord. Is predicted to encode a protein with the following domains: Haloacid dehalogenase-like hydrolase; Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal; HAD-like superfamily; HAD hydrolase, subfamily IA; and HAD superfamily. WB:WBGene00009513 sfxn-1.2 Predicted to enable serine transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Predicted to be located in mitochondrial membrane. Is an ortholog of human SFXN1 (sideroflexin 1) and SFXN3 (sideroflexin 3). WB:WBGene00009514 F37H8.5 Predicted to enable oxidoreductase activity. Located in cytoplasm. Expressed in ventral nerve cord. Is an ortholog of human IFI30 (IFI30 lysosomal thiol reductase). WB:WBGene00009515 clec-170 Enriched in AIZL; AIZR; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00009516 F38A1.2 No description available WB:WBGene00009517 clec-167 Predicted to be located in membrane. WB:WBGene00009518 clec-166 Expressed in rectum. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00009519 F38A1.6 Enriched in NSM and intestine based on tiling array studies. Is affected by several genes including sir-2.1; smg-2; and mir-34 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00009520 clec-168 Is affected by several genes including daf-2; eat-2; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including tryptophan; CGP37157; and cadmium based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00009521 F38A1.8 Predicted to enable GTPase activity and signal recognition particle binding activity. Predicted to be involved in protein targeting to ER. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of signal recognition particle receptor complex. Is an ortholog of human SRPRA (SRP receptor subunit alpha). WB:WBGene00009522 F38A1.9 Enriched in B cell; MSpaaaaa; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; indole; and stavudine based on RNA-seq and microarray studies. WB:WBGene00009523 clec-165 Enriched in OLL; PVD; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00009524 F38A1.11 Is affected by several genes including clk-1; mex-3; and mex-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Cadmium Chloride; resveratrol; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00009525 F38A1.13 Enriched in MC neuron; MCL; MCR; and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-2; clk-1; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00009526 clec-169 Enriched in Z1; Z4; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-five chemicals including tryptophan; 1-methylnicotinamide; and nicotinic acid based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00009527 C02B4.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00009528 F38A6.4 Enriched in germline precursor cell; hypodermis; rectal epithelial cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00009529 F38B2.2 Enriched in neurons and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including D-glucose; Zidovudine; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Uncharacterized protein F10E9.3-like. WB:WBGene00009530 F38B2.3 Predicted to be located in membrane. WB:WBGene00009531 F38B2.4 Predicted to enable adenylate kinase activity. Predicted to be involved in nucleotide metabolic process and phosphorylation. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in congenital nonspherocytic hemolytic anemia and obesity. Is an ortholog of human AK1 (adenylate kinase 1). WB:WBGene00009532 ccch-1 Predicted to enable mRNA binding activity and metal ion binding activity. Located in sarcoplasmic reticulum. Expressed in GABAergic neurons; cholinergic neurons; head neurons; and intestine. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein). WB:WBGene00009533 F38B7.2 Predicted to be located in membrane. WB:WBGene00009534 F38B7.3 Predicted to be involved in regulation of cell differentiation. Predicted to be located in membrane. WB:WBGene00009535 F38C2.1 Enriched in NSM based on tiling array studies. Is affected by several genes including csr-1; pqm-1; and dop-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including indole; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: NTF2-like domain superfamily. WB:WBGene00009536 F38C2.4 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00009537 ccch-2 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be located in cytosol. Expressed in dorsal nerve cord; head muscle; head neurons; intestine; and ventral nerve cord. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein); ZFP36L1 (ZFP36 ring finger protein like 1); and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00009538 clec-191 Is affected by hpl-2 and rsr-2 based on tiling array studies. Is affected by four chemicals including Progesterone; Atrazine; and fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; C-type lectin fold; and PAN-3 domain. WB:WBGene00009539 F38C2.7 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be located in cytosol. Expressed widely. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein); ZFP36L1 (ZFP36 ring finger protein like 1); and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00009540 hlh-31 Predicted to enable DNA-binding transcription factor activity and E-box binding activity. Predicted to be involved in neuron differentiation; positive regulation of transcription by RNA polymerase II; and sensory organ development. Predicted to be located in nucleus. Is an ortholog of human BHLHE22 (basic helix-loop-helix family member e22). WB:WBGene00009541 cutl-17 Predicted to be located in membrane. WB:WBGene00009542 copb-2 Predicted to enable structural molecule activity. Involved in embryo development; intracellular protein transport; and oocyte development. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be part of COPI vesicle coat. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 19. Is an ortholog of human COPB2 (COPI coat complex subunit beta 2). WB:WBGene00009543 F38E11.6 Predicted to enable adenylate kinase activity and nucleoside triphosphate adenylate kinase activity. Predicted to be involved in AMP metabolic process and nucleoside triphosphate biosynthetic process. Predicted to be located in mitochondrial matrix. WB:WBGene00009544 F38E11.9 Enriched in head mesodermal cell; intestine; neurons; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00009546 fbxb-3 Enriched in several structures, including ABalappaap; ABplapaaaa; MC neuron; interfacial epithelial cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00009547 F38H4.3 Enriched in excretory system; neurons; pharynx; and posterior arcade cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009548 F38H4.4 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00009549 F38H4.5 Enriched in AVK and germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; rotenone; and Sodium Chloride based on microarray and RNA-seq studies. Human DDAH2 enables dimethylargininase activity. Is predicted to encode a protein with the following domain: N,N dimethylarginine dimethylhydrolase, eukaryotic. Is an ortholog of human DDAH2 (DDAH family member 2, ADMA-independent). WB:WBGene00009550 F38H4.6 Predicted to be located in cytoskeleton. WB:WBGene00009551 mob-1 Predicted to enable protein kinase activator activity. Predicted to be involved in hippo signaling and positive regulation of protein phosphorylation. Predicted to be located in cytoplasm and nucleus. WB:WBGene00009552 piki-1 Predicted to enable 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in several processes, including phagosome maturation involved in apoptotic cell clearance; phosphatidylinositol-3-phosphate biosynthetic process; and positive regulation of phagocytosis, engulfment. Located in early phagosome and pseudopodium. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha) and PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta). WB:WBGene00009553 hinf-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of human HINFP (histone H4 transcription factor). WB:WBGene00009554 F39B2.3 Predicted to enable NADPH binding activity; NADPH:quinone reductase activity; and mRNA 3'-UTR binding activity. Predicted to be located in cytosol. Is an ortholog of human CRYZ (crystallin zeta). WB:WBGene00009555 C02B4.t2 Is affected by daf-12 based on tiling array studies. WB:WBGene00009556 F39B2.5 Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to be part of phosphatidylinositol 3-kinase complex. Is an ortholog of human SOCS6 (suppressor of cytokine signaling 6) and SOCS7 (suppressor of cytokine signaling 7). WB:WBGene00009557 mtcu-1 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in tRNA methylation and tRNA wobble uridine modification. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 23. Is an ortholog of human GTPBP3 (GTP binding protein 3, mitochondrial). WB:WBGene00009558 F39B2.8 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in head neurons; motor neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1E. Is an ortholog of human GPR158 (G protein-coupled receptor 158) and GPR179 (G protein-coupled receptor 179). WB:WBGene00009559 mtx-1 Predicted to be involved in mitochondrion organization. Predicted to be located in cytoplasm. Predicted to be part of SAM complex. Is an ortholog of human MTX3 (metaxin 3). WB:WBGene00009560 psa-3 Enables transcription coactivator binding activity. Involved in regulation of asymmetric cell division. Located in nucleus. Expressed in several structures, including TL.aa; TL.pa; TR.aa; TR.pa; and hypodermal cell. WB:WBGene00009561 F39D8.3 Enriched in several structures, including ADE sheath cell; anterior ganglion (ant); anterior hypodermis; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by fourteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cystine-knot cytokine. WB:WBGene00009562 flp-22 Enables neuropeptide receptor binding activity. Involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in head neurons; interneuron; somatic neurons; and uv1. WB:WBGene00009563 F39H2.3 Predicted to be involved in iron-sulfur cluster assembly. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 74 and multiple mitochondrial dysfunctions syndrome 3. Is an ortholog of human IBA57 (iron-sulfur cluster assembly factor IBA57). WB:WBGene00009565 F39H11.1 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by five chemicals including paraquat; resveratrol; and Humic Substances based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SWR1-complex protein 5/Craniofacial development protein 1/2; Bucentaur or craniofacial development; and BCNT-C domain. Is an ortholog of human CFDP1 (craniofacial development protein 1). WB:WBGene00009566 srsx-1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00009567 srbc-25 Predicted to be located in membrane. WB:WBGene00009568 srbc-26 Predicted to be located in membrane. WB:WBGene00009569 srz-66 Predicted to be located in membrane. Expressed in ADLL; ADLR; and neurons. WB:WBGene00009570 srz-65 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00009571 F40D4.12 Enriched in AFD and intestine based on tiling array and RNA-seq studies. Is affected by several genes including elt-2; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00009572 F40D4.13 Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. WB:WBGene00009573 F40E10.5 Enriched in anterior hypodermis; arcade cell; mechanosensory neurons; pharyngeal-intestinal valve; and pharynx based on microarray; tiling array; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including 1-methylnicotinamide; rotenone; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00009574 F40E10.6 Predicted to be located in membrane. Expressed in several structures, including egg-laying apparatus; nervous system; pharyngeal-intestinal valve; rectal valve cell; and tail hypodermis. Is an ortholog of human TMEM184B (transmembrane protein 184B). WB:WBGene00009575 F40F8.1 Enables UMP kinase activity. Involved in UDP biosynthetic process. Predicted to be located in cytoplasm and nucleus. Expressed in head and neurons. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human CMPK1 (cytidine/uridine monophosphate kinase 1). WB:WBGene00009576 F40F8.3 Predicted to be located in membrane. Is an ortholog of human TMEM42 (transmembrane protein 42). WB:WBGene00009577 F40F8.4 Enriched in AFD; AMshL; AMshR; amphid sheath cell; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00009578 F40F8.5 Enriched in distal tip cell; head mesodermal cell; intestine; muscle cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including methylmercury hydroxide; rotenone; and D-glucopyranose based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009579 arrd-6 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Expressed in amphid process; head ganglion; nerve ring; tail neurons; and ventral nerve cord. Is an ortholog of human TXNIP (thioredoxin interacting protein). WB:WBGene00009580 xbx-6 Predicted to be involved in negative regulation of apoptotic signaling pathway. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Expressed in neurons; pharyngeal muscle cell; tail; and ventral nerve cord. Is an ortholog of human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1). WB:WBGene00009581 F40F9.3 Enriched in ABplpppaaa; ABprpppaaa; AUA; germ line; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-five chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterized protein T15H9.4-like and PDZ superfamily. WB:WBGene00009582 slcr-46.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00009583 aagr-3 Enables alpha-1,4-glucosidase activity. Involved in glycogen catabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in polycystic kidney disease 3 and polycystic liver disease. Is an ortholog of human GANAB (glucosidase II alpha subunit). WB:WBGene00009584 drap-1 Predicted to enable RNA polymerase II general transcription initiation factor activity and core promoter sequence-specific DNA binding activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of negative cofactor 2 complex. Is an ortholog of human DRAP1 (DR1 associated protein 1). WB:WBGene00009585 cal-7 Predicted to enable calcium ion binding activity. Predicted to be part of myosin II complex. WB:WBGene00009586 F40F9.10 Predicted to enable tRNA methyltransferase activity. Predicted to be involved in tRNA methylation and wybutosine biosynthetic process. Predicted to be located in cytoplasm. Is an ortholog of human TRMT12 (tRNA methyltransferase 12 homolog). WB:WBGene00009587 mig-38 Predicted to enable copper ion binding activity; primary amine oxidase activity; and quinone binding activity. Predicted to be involved in amine metabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in gonad; head; neurons; somatic gonad precursor; and tail. WB:WBGene00009588 F40F11.3 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; germ line; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by twelve chemicals including hydrogen sulfide; rotenone; and levamisole based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: COMPASS (Complex proteins associated with Set1p) component shg1. WB:WBGene00009589 F40F11.4 Predicted to enable calcium ion binding activity. WB:WBGene00009590 ttr-4 Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00009591 F40F12.2 No description available WB:WBGene00009592 F40F12.3 Predicted to be located in membrane. WB:WBGene00009593 mam-7 Predicted to be located in membrane. WB:WBGene00009594 cyld-1 Predicted to enable K63-linked deubiquitinase activity and cysteine-type deubiquitinase activity. Predicted to be located in cytosol. Expressed in several structures, including arcade cell; pharyngeal cell; pharyngeal-intestinal valve; rectal gland cell; and spermatheca. Human ortholog(s) of this gene implicated in Brooke-Spiegler syndrome. Is an ortholog of human CYLD (CYLD lysine 63 deubiquitinase). WB:WBGene00009595 cbp-3 Predicted to enable histone acetyltransferase activity and metal ion binding activity. Involved in PERK-mediated unfolded protein response. Predicted to be located in nucleus. WB:WBGene00009596 sre-8 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00009597 F40G12.2 Enriched in NSM and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by paraquat based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009598 F40G12.3 Is affected by several genes including alg-1; mex-1; and drh-3 based on RNA-seq and microarray studies. Is affected by Atrazine based on microarray studies. WB:WBGene00009599 F40G12.4 Enriched in amphid sheath cell and germ line based on RNA-seq studies. Is affected by several genes including rrf-3; pgl-1; and eri-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00009600 F40G12.5 Enriched in G2; MSaaaaapa; W cell; amphid sheath cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Rifampin; indole; and 4-bromodiphenyl ether based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00009601 F40G12.6 Enriched in AMshL; AMshR; amphid sheath cell; and arc ant V based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; let-60; and elt-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00009602 F40G12.7 Is affected by several genes including daf-2; clk-1; and lin-15B based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Alovudine; and Ag nanoparticles based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1265 and Protein of unknown function (DUF1265). WB:WBGene00009603 srt-33 Predicted to be located in membrane. WB:WBGene00009604 F40G12.9 Is affected by several genes including daf-2; eat-2; and alg-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: CC domain. WB:WBGene00009605 F40G12.10 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00009606 F40G12.11 Expressed in germ line. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009607 oac-26 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00009608 nhr-265 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00009609 oac-27 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00009610 oac-28 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00009611 F41D3.6 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00009612 F41D3.7 Predicted to be located in membrane. WB:WBGene00009613 F41D3.8 Is affected by several genes including daf-16; sir-2.1; and cyc-1 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00009614 F41D3.9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-12; clk-1; and daf-18 based on tiling array; microarray; and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1647) and Protein of unknown function DUF1647. WB:WBGene00009615 oac-25 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. WB:WBGene00009616 F41D3.11 Predicted to be located in membrane. WB:WBGene00009617 slc-9B.1 Predicted to enable antiporter activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in membrane. Expressed in excretory canal; excretory cell; and pharynx. Is an ortholog of human SLC9B1 (solute carrier family 9 member B1). WB:WBGene00009618 F41E7.2 Predicted to enable antiporter activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC9B1 (solute carrier family 9 member B1) and SLC9B2 (solute carrier family 9 member B2). WB:WBGene00009619 npr-6 Predicted to enable neuropeptide binding activity and neuropeptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection and plasma membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; morbid obesity; and peripheral artery disease. Is an ortholog of human NPY2R (neuropeptide Y receptor Y2). WB:WBGene00009620 fip-5 Enriched in PLM; PVW; germline precursor cell; seam cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty chemicals including rotenone; bisphenol A; and juglone based on RNA-seq and microarray studies. WB:WBGene00009621 fipr-21 Enriched in germline precursor cell; hypodermis; intestine; seam cell; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including nicotinic acid; rotenone; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009622 F41E7.6 Predicted to enable carnitine O-octanoyltransferase activity. Predicted to be located in peroxisome. Expressed in anal depressor muscle; anal sphincter muscle; intestinal muscle; neurons; and pharyngeal-intestinal valve. Is an ortholog of human CROT (carnitine O-octanoyltransferase). WB:WBGene00009623 F41E7.7 Enriched in neurons and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and elt-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including D-glucose; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00009624 cnc-8 Enriched in ABplapaaap; ABprapaaap; hypodermis; and intestine based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including rotenone; D-glucose; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00009625 F41E7.9 Enriched in MSaapaapa; MSpapaapa; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Tunicamycin; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00009626 F42A8.1 Expressed in head; intestine; and vulva. Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like. WB:WBGene00009627 cup-15 Involved in lysosome organization. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 5. Is an ortholog of human OSTM1 (osteoclastogenesis associated transmembrane protein 1). WB:WBGene00009628 tatn-1 Predicted to enable L-tyrosine:2-oxoglutarate aminotransferase activity. Involved in dauer entry. Human ortholog(s) of this gene implicated in tyrosinemia type II. Is an ortholog of human TAT (tyrosine aminotransferase). WB:WBGene00009629 sprr-2 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and chemotaxis. Predicted to be located in plasma membrane. Expressed in SDQ and neurons. WB:WBGene00009630 F42E8.1 Enriched in excretory gland cell; lateral ganglion; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including pgl-1; aak-2; and fbf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00009631 F42E8.2 Is affected by several genes including daf-2; age-1; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Acrylamide based on microarray and RNA-seq studies. WB:WBGene00009632 ttyh-1 Predicted to enable intracellular calcium activated chloride channel activity and volume-sensitive chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human TTYH3 (tweety family member 3). WB:WBGene00009633 F42E11.3 Predicted to be located in membrane. WB:WBGene00009634 nspc-9 Enriched in excretory gland cell and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including rotenone; mianserin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00009635 F42F12.3 Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Involved in innate immune response. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in breast carcinoma; hypospadias; and prostate disease (multiple). Is an ortholog of human SRD5A2 (steroid 5 alpha-reductase 2). WB:WBGene00009636 F42F12.4 Predicted to enable acireductone dioxygenase [iron(II)-requiring] activity. Predicted to be involved in methionine metabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human ADI1 (acireductone dioxygenase 1). WB:WBGene00009637 nspc-13 Enriched in excretory gland cell and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty chemicals including rotenone; mianserin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00009638 nspc-14 Enriched in ASER and excretory gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by fifteen chemicals including rotenone; mianserin; and D-glucose based on RNA-seq studies. WB:WBGene00009639 nspc-15 Enriched in excretory gland cell and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including mianserin; fluvastatin; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00009640 nspc-10 Enriched in excretory gland cell; intestine; and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by twenty-two chemicals including hydrogen sulfide; D-glucose; and bisphenol A based on microarray and RNA-seq studies. WB:WBGene00009641 F42G4.2 Enriched in ABplpppaaa; ABprpppaaa; arcade cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including nicotinic acid; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00009642 F42G4.5 Enriched in arcade cell; head mesodermal cell; intestine; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Tunicamycin; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00009643 F42G4.6 Enriched in germ line; intestine; and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including mianserin; D-glucose; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009644 F42G4.7 Predicted to be located in membrane. WB:WBGene00009645 F42G10.1 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00009646 F42H11.1 Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00009647 phlp-2 Predicted to enable metal ion binding activity and myosin phosphatase activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in neurons. Human ortholog(s) of this gene implicated in prostate cancer. Is an ortholog of human PHLPP2 (PH domain and leucine rich repeat protein phosphatase 2). WB:WBGene00009648 zhit-2 Enriched in AFD; germ line; intestine; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including rotenone; Cry5B; and Zidovudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: Zinc finger, HIT-type; HIT zinc finger; and Zinc finger HIT domain-containing protein 2. Is an ortholog of human ZNHIT2 (zinc finger HIT-type containing 2). WB:WBGene00009649 F43C1.5 Predicted to enable ubiquitin binding activity. Is an ortholog of human CUEDC1 (CUE domain containing 1). WB:WBGene00009650 ccnk-1 Enables cyclin-dependent protein serine/threonine kinase activator activity. Involved in nematode larval development. Located in nucleus. Is an ortholog of human CCNK (cyclin K). WB:WBGene00009651 F43D2.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00009652 F43D2.3 Enriched in K cell; K' cell; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00009653 ptr-25 Predicted to be involved in endocytosis and molting cycle. Located in centrosome. Expressed in head neurons; interneuron; and muscle cell. WB:WBGene00009654 sly-1 Predicted to enable syntaxin binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intracellular protein transport. Predicted to be located in Golgi membrane. Is an ortholog of human SCFD1 (sec1 family domain containing 1). WB:WBGene00009656 F43G6.3 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including rotenone; manganese chloride; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009657 F43G6.4 Enriched in several structures, including g2; muscle cell; neurons; rectum; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sek-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009658 pap-3 Predicted to enable RNA binding activity; ion binding activity; and poly(A) RNA polymerase activity. Predicted to be involved in mRNA polyadenylation. Predicted to be located in nucleus. Is an ortholog of human PAPOLB (poly(A) polymerase beta). WB:WBGene00009659 F43G6.7 Enriched in NSM; germ line; and pharyngeal muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; rotenone; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00009660 F43G6.8 Predicted to enable metal ion binding activity. WB:WBGene00009661 patr-1 Predicted to enable RNA binding activity. Involved in determination of adult lifespan. Located in P-body. Is an ortholog of human PATL1 (PAT1 homolog 1, processing body mRNA decay factor) and PATL2 (PAT1 homolog 2). WB:WBGene00009662 F43G6.10 Enriched in AFD; PLML; PLMR; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00009663 hda-5 Predicted to enable histone deacetylase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be part of histone deacetylase complex. Is an ortholog of human HDAC10 (histone deacetylase 10). WB:WBGene00009664 idha-1 Predicted to enable isocitrate dehydrogenase (NAD+) activity. Involved in protein folding. Located in mitochondrion. Expressed in head and tail. Human ortholog(s) of this gene implicated in retinitis pigmentosa 90. Is an ortholog of human IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha). WB:WBGene00009665 lmd-1 Predicted to be located in membrane. Is an ortholog of human LYSMD4 (LysM domain containing 4). WB:WBGene00009666 slc-25A42 Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in head. Is an ortholog of human SLC25A42 (solute carrier family 25 member 42). WB:WBGene00009667 F43G9.4 Enriched in body wall muscle cell; coelomocyte; germ line; and muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; dpy-10; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by ten chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00009668 cfim-1 Enables identical protein binding activity. Predicted to be involved in mRNA processing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of mRNA cleavage factor complex. Is an ortholog of human NUDT21 (nudix hydrolase 21). WB:WBGene00009669 F43G9.7 No description available WB:WBGene00009670 F43G9.8 Predicted to be located in membrane. WB:WBGene00009671 mfap-1 Involved in regulation of alternative mRNA splicing, via spliceosome. Located in nucleus. Expressed in body wall musculature; intestine; pharynx; and vulval muscle. Is an ortholog of human MFAP1 (microfibril associated protein 1). WB:WBGene00009672 mog-7 Predicted to enable DNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Expressed in germ cell; oocyte; somatic cell; and sperm. Is an ortholog of human GCFC2 (GC-rich sequence DNA-binding factor 2) and PAXBP1 (PAX3 and PAX7 binding protein 1). WB:WBGene00009673 F43G9.13 Predicted to be located in membrane. Is an ortholog of human TMEM170A (transmembrane protein 170A). WB:WBGene00009674 nucb-1 Predicted to enable calcium ion binding activity. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment. Expressed in body wall musculature; intestinal cell; neurons; and non-striated muscle. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human NUCB1 (nucleobindin 1) and NUCB2 (nucleobindin 2). WB:WBGene00009675 F44A6.3 Enriched in several structures, including ASER; head mesodermal cell; intestine; male distal tip cell; and tail precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009676 F44A6.4 Enriched in hypodermis; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009677 F44A6.5 Enriched in ASER; PLM; germline precursor cell; intestine; and tail precursor cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including Ethanol; Tunicamycin; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00009678 magu-4 Predicted to be involved in negative regulation of hippo signaling. Expressed in hypodermis; neurons; pharynx; spermatheca; and vulval cell. Is an ortholog of human DLG5 (discs large MAGUK scaffold protein 5). WB:WBGene00009679 F44D12.2 Predicted to be located in membrane. WB:WBGene00009680 msd-1 Located in cell body and pseudopodium. WB:WBGene00009681 gipc-2 Expressed in spermatid. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 15 and oculopharyngodistal myopathy 2. Human GIPC1 enables signaling receptor binding activity. Is predicted to encode a protein with the following domains: PDZ domain-containing protein GIPC1/2/3; PDZ domain; and PDZ superfamily. Is an ortholog of human GIPC1 (GIPC PDZ domain containing family member 1) and GIPC3 (GIPC PDZ domain containing family member 3). WB:WBGene00009682 msd-2 Located in cell body and pseudopodium. WB:WBGene00009683 F44D12.6 Predicted to be located in membrane. WB:WBGene00009684 msd-3 Located in cell body and pseudopodium. WB:WBGene00009685 F44D12.8 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including methylmercury hydroxide; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00009686 ent-7 Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Is an ortholog of human SLC29A3 (solute carrier family 29 member 3). WB:WBGene00009687 F44D12.10 Predicted to enable metal ion binding activity. WB:WBGene00009688 F44E5.1 Enriched in germ line; muscle cell; neurons; and retrovesicular ganglion based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and proteomic studies. Is affected by six chemicals including rotenone; D-glucose; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00009689 F44E5.2 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00009690 F44E5.3 Enriched in body wall muscle cell; intestinal muscle; neurons; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and pgl-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00009691 F44E5.4 Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Predicted to be involved in chaperone cofactor-dependent protein refolding and protein refolding. Predicted to be located in cytosol; nucleus; and plasma membrane. Is an ortholog of human HSPA6 (heat shock protein family A (Hsp70) member 6) and HSPA7 (heat shock protein family A (Hsp70) member 7 (pseudogene)). WB:WBGene00009692 F44E5.5 Predicted to enable ATP binding activity and ATP-dependent protein folding chaperone. Is an ortholog of human HSPA6 (heat shock protein family A (Hsp70) member 6) and HSPA7 (heat shock protein family A (Hsp70) member 7 (pseudogene)). WB:WBGene00009693 F44F1.1 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including methylmercuric chloride; cholesterol; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00009695 clp-8 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. WB:WBGene00009696 F44F1.4 Predicted to be involved in autophagy. WB:WBGene00009697 F44F1.5 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009698 F44F1.6 Predicted to be involved in autophagy. Located in cytoplasm. WB:WBGene00009700 lurp-1 Predicted to be located in membrane. WB:WBGene00009701 egg-3 Enables protein kinase binding activity. Involved in cortical actin cytoskeleton organization; female gamete generation; and positive regulation of protein localization to cell cortex. Located in cell cortex. WB:WBGene00009702 F44F4.3 Predicted to be located in membrane. WB:WBGene00009703 F44F4.8 No description available WB:WBGene00009704 F44F4.9 Predicted to be located in membrane. WB:WBGene00009705 F44F4.10 Enriched in germ line and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00009706 argk-1 Predicted to enable kinase activity. Involved in ATP metabolic process and generation of precursor metabolites and energy. Expressed in IL socket cell and OL socket cell. Is an ortholog of several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1B (creatine kinase, mitochondrial 1B). WB:WBGene00009707 srxa-16 Predicted to be located in membrane. WB:WBGene00009708 F44G3.7 Predicted to be located in extracellular space. WB:WBGene00009709 fbxa-144 Enriched in ALM; AVA; and PLM based on tiling array and microarray studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Zidovudine; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00009710 F44G3.10 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00009711 F44G4.1 Predicted to enable rRNA primary transcript binding activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be located in nucleolus. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human RPF1 (ribosome production factor 1 homolog). WB:WBGene00009712 ndub-2 Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is an ortholog of human NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2). WB:WBGene00009713 F44G4.3 Predicted to be located in membrane. WB:WBGene00009714 F44G4.5 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00009715 F44G4.6 Predicted to be located in membrane. WB:WBGene00009716 F44G4.7 Enriched in neurons and phasmid neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on microarray and RNA-seq studies. Is affected by four chemicals including rotenone; cholesterol; and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00009717 dep-1 Enables phosphatase activity. Involved in positive regulation of vulval development and vulval cell fate specification. Predicted to be located in membrane. Expressed in several structures, including P5.paa; P5.pap; P5.ppa; P5.ppp; and P7.paa. Human ortholog(s) of this gene implicated in several diseases, including breast angiosarcoma; carcinoma (multiple); and central nervous system cancer (multiple). Is an ortholog of human PTPRB (protein tyrosine phosphatase receptor type B). WB:WBGene00009720 idpp-3 Enriched in excretory system and lateral ganglion based on single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including 1-methylnicotinamide; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009721 F45D3.1 Enriched in AMsoL; AMsoR; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including diallyl trisulfide; hydrogen sulfide; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Pes-10. WB:WBGene00009722 F45D3.2 Predicted to enable DNA binding activity. Expressed in body wall musculature. WB:WBGene00009723 F45D3.3 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and amphid neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; rotenone; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00009724 F45D3.4 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including Ethanol; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00009725 F45E6.1 Enriched in coelomocyte based on single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies. WB:WBGene00009726 tbc-13 Predicted to enable GTPase activator activity. Predicted to be involved in intracellular protein transport. Is an ortholog of human TBC1D13 (TBC1 domain family member 13). WB:WBGene00009727 lips-1 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00009728 sdz-19 Predicted to be involved in negative regulation of vulval development. WB:WBGene00009729 F45E10.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00009730 myo-6 Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in muscle contraction and sarcomere organization. Predicted to be located in cytoplasm and myosin filament. Predicted to be part of myosin II complex. Human ortholog(s) of this gene implicated in several diseases, including congenital heart disease (multiple); distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3). WB:WBGene00009731 exo-1 Predicted to enable 5'-3' DNA exonuclease activity and 5'-flap endonuclease activity. Predicted to be involved in DNA recombination and mismatch repair. Predicted to be located in nucleus. Is an ortholog of human EXO1 (exonuclease 1). WB:WBGene00009732 cope-1 Predicted to enable structural molecule activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intra-Golgi vesicle-mediated transport. Located in mitochondrion. Is an ortholog of human COPE (COPI coat complex subunit epsilon). WB:WBGene00009733 F45G2.7 Enriched in ABalapppaa; germ line; germline precursor cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; clk-1; and isp-1 based on microarray; proteomic; and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; mianserin; and stavudine based on microarray and RNA-seq studies. WB:WBGene00009734 F45G2.8 Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia Megarbane-Dagher-Melike type. Is an ortholog of human PAM16 (presequence translocase associated motor 16). WB:WBGene00009735 F45G2.9 Predicted to enable rRNA (uridine-2'-O-)-methyltransferase activity. Predicted to be involved in RNA methylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 17. Is an ortholog of human MRM2 (mitochondrial rRNA methyltransferase 2). WB:WBGene00009736 ciao-2B Predicted to be involved in iron-sulfur cluster assembly. Predicted to be part of CIA complex. Is an ortholog of human CIAO2B (cytosolic iron-sulfur assembly component 2B). WB:WBGene00009738 hecw-1 Predicted to enable ubiquitin protein ligase activity. Involved in regulation of defense response to bacterium. Predicted to be located in cytoplasm. Expressed in SMDVL and head neurons. Is an ortholog of human HECW1 (HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1) and HECW2 (HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2). WB:WBGene00009739 F45H10.2 Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 4. Is an ortholog of human UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII). WB:WBGene00009740 ndua-7 Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Is an ortholog of human NDUFA7 (NADH:ubiquinone oxidoreductase subunit A7). WB:WBGene00009741 drr-1 Predicted to be located in membrane. WB:WBGene00009742 F45H10.5 Predicted to be located in membrane. WB:WBGene00009743 sptf-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in neuron differentiation and positive regulation of gene expression. Expressed in ASJ; epithelial cell; intestinal cell; and pharyngeal cell. Human ortholog(s) of this gene implicated in aortic valve stenosis and osteogenesis imperfecta type 12. Is an ortholog of human SP7 (Sp7 transcription factor). WB:WBGene00009744 hpo-35 Enriched in AVK and germ line based on RNA-seq studies. Is affected by several genes including daf-2; let-7; and gld-1 based on RNA-seq; proteomic; and microarray studies. Is affected by seven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00009745 cox-19 Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human COX19 (cytochrome c oxidase assembly factor COX19). WB:WBGene00009746 F46A8.3 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00009747 F46A8.4 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00009748 F46A8.5 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00009749 F46A8.6 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00009750 F46A8.7 Enriched in AFD; ASER; neurons; and sensory neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including Tunicamycin; Cadmium Chloride; and stavudine based on microarray and RNA-seq studies. WB:WBGene00009751 F46A8.8 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00009752 F46A8.9 Is affected by several genes including daf-2; dpy-10; and eat-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including methylmercuric chloride; Cisplatin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00009753 scrm-6 Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be located in plasma membrane. WB:WBGene00009754 F46A9.1 Enriched in RIS; germ line; sensory neurons; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including nicotinic acid; rotenone; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00009755 F46A9.2 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00009756 F46B3.1 Enriched in NSM based on tiling array studies. Is affected by several genes including pmk-1; clk-1; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00009757 F46B3.2 Enriched in dopaminergic neurons and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including age-1; let-60; and pgl-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00009758 ttr-11 Predicted to be located in cell surface and extracellular region. Expressed in DVA; HSNL; HSNR; excretory gland cell; and hyp10. WB:WBGene00009759 ttr-12 Predicted to be located in cell surface and extracellular region. WB:WBGene00009760 F46B3.7 Enriched in AVK; germline precursor cell; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including lin-4; lin-14; and daf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including tryptophan; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00009761 F46B3.8 Is affected by several genes including sir-2.1; hpl-2; and mir-34 based on tiling array and microarray studies. Is affected by fluoranthene; tetrabromobisphenol A; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00009762 F46B3.9 Is affected by several genes including daf-16; daf-2; and csr-1 based on microarray and RNA-seq studies. Is affected by Ag nanoparticles and adsorbable organic bromine compound based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Follistatin-like, N-terminal. WB:WBGene00009763 srz-18 Predicted to be located in membrane. WB:WBGene00009764 srz-17 Is affected by several genes including daf-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. WB:WBGene00009765 F46B3.14 Is affected by several genes including clk-1; tph-1; and csr-1 based on RNA-seq and microarray studies. Is affected by Diazinon and adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domain: Follistatin-like, N-terminal. WB:WBGene00009766 F46B3.15 Enriched in germ line based on RNA-seq studies. Is affected by several genes including rrf-3; sir-2.1; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by Sirolimus and allantoin based on microarray studies. WB:WBGene00009767 F46B3.16 Is affected by several genes including eat-2; clk-1; and prg-1 based on tiling array; microarray; and RNA-seq studies. Is affected by resveratrol; fluoranthene; and adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domain: F-box protein she-1-like. WB:WBGene00009768 F46B6.2 Predicted to be located in membrane. WB:WBGene00009769 F46B6.4 Predicted to enable GTP binding activity and metal ion binding activity. Predicted to be involved in tRNA methylation and tRNA wobble uridine modification. Predicted to be located in mitochondrion. Is an ortholog of human GTPBP6 (GTP binding protein 6 (putative)). WB:WBGene00009770 F46B6.5 Predicted to be involved in tRNA methylation and tRNA wobble uridine modification. Predicted to be located in mitochondrion. WB:WBGene00009771 F46B6.6 Predicted to enable translation initiation factor activity. Predicted to be involved in mitochondrial translational initiation. Predicted to be located in mitochondrion. Is an ortholog of human MTIF2 (mitochondrial translational initiation factor 2). WB:WBGene00009772 ztf-7 Predicted to enable metal ion binding activity. Is an ortholog of human ZNF277 (zinc finger protein 277). WB:WBGene00009773 lipl-2 Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be involved in lipid catabolic process. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). WB:WBGene00009774 F46B6.9 Predicted to be located in membrane. WB:WBGene00009775 F46B6.10 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including hydrogen sulfide; methylmercuric chloride; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00009776 F46B6.12 Predicted to enable zinc ion binding activity. Is an ortholog of human CZIB (CXXC motif containing zinc binding protein). WB:WBGene00009777 F46C3.2 Predicted to be located in membrane. WB:WBGene00009778 F46C5.1 Predicted to be located in membrane. WB:WBGene00009779 F46C5.2 Predicted to be located in membrane. WB:WBGene00009780 F46C5.4 Predicted to be involved in regulation of cholinergic synaptic transmission and sleep. Predicted to be located in extracellular region. WB:WBGene00009781 F46C5.6 Predicted to enable protein phosphatase regulator activity. Predicted to be located in cytosol. Predicted to be part of protein serine/threonine phosphatase complex. Is an ortholog of human PPP4R4 (protein phosphatase 4 regulatory subunit 4). WB:WBGene00009782 F46C5.7 Predicted to be located in membrane. WB:WBGene00009783 rer-1 Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum and membrane. Is an ortholog of human RER1 (retention in endoplasmic reticulum sorting receptor 1). WB:WBGene00009784 F46C5.9 Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum. Is an ortholog of human TBL2 (transducin beta like 2). WB:WBGene00009785 F46C5.10 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00009786 F46F2.1 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on tiling array and RNA-seq studies. Is affected by nine chemicals including aldicarb; stavudine; and metformin based on microarray and RNA-seq studies. WB:WBGene00009787 F46F2.3 Expressed in hypodermis. WB:WBGene00009788 F46F2.4 Enriched in AFD based on RNA-seq studies. Is affected by several genes including lin-4; eat-2; and lin-14 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; metformin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00009789 F46F2.5 Enriched in neurons based on RNA-seq; single-cell RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00009790 lgc-44 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00009791 F46F3.3 Enriched in germline precursor cell and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercury hydroxide; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009793 pkn-1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Located in M band and striated muscle dense body. Expressed in neurons and pharyngeal muscle cell. Is an ortholog of human PKN3 (protein kinase N3). WB:WBGene00009796 F46G10.1 Predicted to be involved in protein homooligomerization. WB:WBGene00009797 F46G10.2 Predicted to be located in membrane. WB:WBGene00009798 F46G10.4 Predicted to be involved in lipid metabolic process. Predicted to be located in membrane. WB:WBGene00009799 lgc-47 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00009800 rrc-1 Enables GTPase activator activity. Predicted to be involved in signal transduction. Expressed in GLRL; GLRR; coelomocyte; excretory cell; and uterine seam cell. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome and coronary artery disease. Is an ortholog of human ARHGAP33 (Rho GTPase activating protein 33). WB:WBGene00009801 ipla-2 Predicted to enable actin filament binding activity. Involved in intestinal lipid catabolic process and response to starvation. Located in cytoplasm. WB:WBGene00009802 F47B8.1 Predicted to be located in membrane. WB:WBGene00009803 F47B8.2 Predicted to be located in membrane. WB:WBGene00009804 F47B8.3 Predicted to be located in mitochondrial matrix. Expressed in several structures, including GABAergic neurons; head muscle; head neurons; intestinal cell; and pharyngeal cell. WB:WBGene00009805 F47B8.4 Involved in innate immune response. Predicted to be located in mitochondrial matrix. WB:WBGene00009806 F47B8.5 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00009807 pepm-1 Predicted to enable aminopeptidase activity. Expressed in vulC; vulD; vulE; and vulF. WB:WBGene00009808 srm-4 Predicted to be located in membrane. Expressed in ciliated neurons. WB:WBGene00009809 F47B8.8 Predicted to enable aminopeptidase activity. Expressed in vulva. WB:WBGene00009810 srm-6 Predicted to be located in membrane. Expressed in amphid neurons; intestine; and retrovesicular ganglion. WB:WBGene00009811 F47B8.10 Predicted to enable glucose 6-phosphate:inorganic phosphate antiporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II; glycogen storage disease Ib; and glycogen storage disease Ic. Is an ortholog of human SLC37A4 (solute carrier family 37 member 4). WB:WBGene00009812 suca-1 Predicted to enable succinate-CoA ligase (ADP-forming) activity. Predicted to be involved in succinyl-CoA metabolic process and tricarboxylic acid cycle. Located in mitochondrion. Expressed in anterior gonad arm. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 5. Is an ortholog of human SUCLA2 (succinate-CoA ligase ADP-forming subunit beta). WB:WBGene00009813 haly-1 Predicted to enable histidine ammonia-lyase activity. Involved in histidine catabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in histidinemia. Is an ortholog of human HAL (histidine ammonia-lyase). WB:WBGene00009814 F47B10.3 Predicted to be located in membrane. Expressed in head neurons and tail neurons. WB:WBGene00009815 F47B10.4 Enriched in ABplppaaaap; ABprppaaaap; hermaphrodite distal tip cell; and male distal tip cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; tph-1; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00009816 F47B10.5 Predicted to be located in membrane. WB:WBGene00009817 F47B10.6 Enriched in NSM; coelomocyte; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including clk-1; hpl-2; and rpn-10 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Doxycycline; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00009818 acbp-3 Predicted to enable fatty-acyl-CoA binding activity. Involved in lipid storage. Predicted to be located in cytoplasm. Expressed in body wall musculature and pharynx. Human ortholog(s) of this gene implicated in retinal dystrophy with leukodystrophy. Is an ortholog of human ACBD4 (acyl-CoA binding domain containing 4) and ACBD5 (acyl-CoA binding domain containing 5). WB:WBGene00009819 F47B10.8 Predicted to be located in membrane. WB:WBGene00009820 F47B10.9 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppppapa; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including rotenone; levamisole; and tert-Butylhydroperoxide based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00009821 F47C8.1 No description available WB:WBGene00009822 clec-113 Enriched in NSM and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including pgl-1; csr-1; and mex-3 based on tiling array and RNA-seq studies. Is affected by four chemicals including Psoralens; Sirolimus; and Ethanol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; and PAN-3 domain. WB:WBGene00009823 gadr-6 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00009824 gpdh-1 Predicted to enable glycerol-3-phosphate dehydrogenase (quinone) activity. Predicted to be involved in NADH oxidation and glycerol-3-phosphate metabolic process. Predicted to be located in cytosol. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Is an ortholog of human GPD1 (glycerol-3-phosphate dehydrogenase 1) and GPD1L (glycerol-3-phosphate dehydrogenase 1 like). WB:WBGene00009825 F47G4.4 Contributes to microtubule severing ATPase activity. Involved in microtubule depolymerization. Part of katanin complex. Human ortholog(s) of this gene implicated in lissencephaly 6. Is an ortholog of human KATNB1 (katanin regulatory subunit B1). WB:WBGene00009826 F47G4.5 Contributes to microtubule severing ATPase activity. Involved in microtubule depolymerization. Part of katanin complex. Expressed in amphid neurons; inner labial neurons; outer labial neurons; and phasmid neurons. WB:WBGene00009827 hmg-6 Predicted to enable DNA binding activity. Predicted to be located in nucleus. Expressed in amphid neurons; head neurons; phasmid neurons; and tail neurons. Is an ortholog of human TOX4 (TOX high mobility group box family member 4). WB:WBGene00009828 F47G4.8 Is affected by several genes including rrf-3; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by aldicarb; cadmium; and allantoin based on microarray studies. WB:WBGene00009829 tmed-10 Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human TMED10 (transmembrane p24 trafficking protein 10). WB:WBGene00009830 cutl-18 Predicted to be located in membrane. WB:WBGene00009831 F47G9.4 Predicted to enable Hsp70 protein binding activity and transmembrane transporter binding activity. Predicted to be located in perinuclear region of cytoplasm. Is an ortholog of human RNF207 (ring finger protein 207). WB:WBGene00009832 F47G9.5 No description available WB:WBGene00009833 F47G9.6 Predicted to enable galactoside binding activity. WB:WBGene00009834 lsy-27 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in neuron differentiation and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in ASE; embryonic cell; head; somatic nervous system; and tail neurons. WB:WBGene00009835 F47H4.2 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABplaapaaa; ABplpaaaaa; and interfacial epithelial cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Tunicamycin; 4-bromodiphenyl ether; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box domain. WB:WBGene00009836 fbxa-185 Enriched in intestine and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; elt-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00009837 fbxa-186 Enriched in intestine based on tiling array studies. Is affected by several genes including daf-16; daf-12; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00009838 fbxa-187 Enriched in OLL; PVD; and neurons based on microarray and tiling array studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by five chemicals including paraquat; cadmium; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00009839 fbxa-188 Enriched in PLM; Z1; Z4; and body wall muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box A protein FB224; HTH domain in Mos1 transposase; and F-box domain. WB:WBGene00009840 fbxa-189 Enriched in several structures, including Z1.p; intestine; male distal tip cell; neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including methylmercuric chloride; bisphenol A; and sesamin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00009841 fbxa-134 Is affected by several genes including eat-2; sir-2.1; and lin-22 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube and Zidovudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and Phosphorylation site. WB:WBGene00009842 igeg-2 Predicted to be located in membrane. WB:WBGene00009843 F48C5.2 Predicted to be involved in proteolysis. Predicted to be located in extracellular region. WB:WBGene00009844 cwp-5 Involved in neuronal signal transduction and response to hermaphrodite contact. Located in cell body; dendrite; and non-motile cilium. Expressed in CEM; HOB; and ray neuron type B. WB:WBGene00009846 F48F5.2 Enriched in URB; germ line; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including hydrogen sulfide; methylmercuric chloride; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00009848 F48F5.6 Predicted to be located in membrane. WB:WBGene00009849 F48F7.3 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Is an ortholog of human B3GALT4 (beta-1,3-galactosyltransferase 4) and B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5). WB:WBGene00009850 F48F7.5 Enriched in germline precursor cell; head mesodermal cell; hypodermis; muscle cell; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by nine chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00009851 F48F7.6 Enriched in body wall muscle cell; excretory cell; head mesodermal cell; hypodermis; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00009852 arrd-24 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC2 (arrestin domain containing 2). WB:WBGene00009853 arrd-27 Enriched in neurons based on RNA-seq studies. Is affected by several genes including clk-1; aak-2; and mex-3 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00009854 clec-31 Predicted to be located in membrane. WB:WBGene00009855 clec-22 Predicted to be located in membrane. WB:WBGene00009856 clec-24 Predicted to be located in membrane. WB:WBGene00009857 clec-28 Predicted to be located in membrane. WB:WBGene00009858 thn-4 Predicted to be located in extracellular region. WB:WBGene00009859 clec-33 Predicted to be located in membrane. WB:WBGene00009860 clec-32 Predicted to be located in membrane. WB:WBGene00009861 fbxb-8 Enriched in several structures, including ABalppappa; ABalpppapa; ABalpppappp; ABalppppaa; and ciliated neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00009862 fbxb-67 Enriched in several structures, including ABalpppappp; ABalppppaa; ABalpppppa; amphid neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and npr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00009863 F49B2.3 Enriched in NSM and body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including aldicarb; methylmercuric chloride; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00009864 F49B2.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00009865 F49B2.6 Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including severe acute respiratory syndrome; severe pre-eclampsia; and uterine disease (multiple). Is an ortholog of human ERAP1 (endoplasmic reticulum aminopeptidase 1). WB:WBGene00009866 F49C5.3 Enriched in ALML; ALMR; BDUL; BDUR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by hydrogen sulfide and Ag nanoparticles based on microarray and RNA-seq studies. WB:WBGene00009867 F49C5.4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Is an ortholog of human NIM1K (NIM1 serine/threonine protein kinase). WB:WBGene00009868 F49C5.5 Is affected by several genes including eat-2; sir-2.1; and met-2 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including fluoranthene; Diazinon; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00009869 F49C5.7 Enriched in M cell; XXX cell; and ciliated neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and csr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by allantoin and Sirolimus based on microarray studies. WB:WBGene00009870 F49C5.8 No description available WB:WBGene00009871 F49C12.1 Predicted to enable transferase activity. Predicted to be located in membrane. WB:WBGene00009872 F49C12.2 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00009873 F49C12.3 Predicted to enable transferase activity. WB:WBGene00009874 F49C12.4 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00009875 F49C12.5 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00009876 F49C12.6 Predicted to enable carbohydrate transmembrane transporter activity. Predicted to be involved in carbohydrate transmembrane transport. Predicted to be located in membrane. Expressed in excretory cell. WB:WBGene00009877 F49C12.7 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00009878 F49C12.9 Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. WB:WBGene00009879 F49C12.10 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00009880 F49C12.11 Expressed in coelomocyte; hypodermis; and neurons. Is predicted to encode a protein with the following domains: Translation machinery associated TMA7 and Phosphorylation site. Is an ortholog of human TMA7 (translation machinery associated 7 homolog). WB:WBGene00009881 F49C12.12 Predicted to enable RNA endonuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis and obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. Predicted to be located in membrane. Is an ortholog of human RNASEK (ribonuclease K). WB:WBGene00009882 vha-17 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in embryo development; embryonic body morphogenesis; and regulation of syncytium formation by plasma membrane fusion. Located in apical junction complex and apical plasma membrane. Expressed in excretory cell; hypodermal cell; and intestine. Is an ortholog of human ATP6V0E2 (ATPase H+ transporting V0 subunit e2). WB:WBGene00009883 nspg-11 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; paraquat; and stearic acid based on RNA-seq and microarray studies. WB:WBGene00009884 F49C12.15 Predicted to be located in cytoplasm and nucleus. WB:WBGene00009885 moc-5 Predicted to enable GTP 3',8'-cyclase activity and cyclic pyranopterin monophosphate synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Predicted to be part of molybdopterin synthase complex. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type A. Is an ortholog of human MOCS1 (molybdenum cofactor synthesis 1). WB:WBGene00009886 F49E2.2 Enriched in several structures, including gonad; mechanosensory neurons; rectal epithelial cell; rectum; and somatic gonad precursor based on microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on RNA-seq; proteomic; and microarray studies. Is affected by thirteen chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SH3-like domain superfamily; SH3 domain; and Phosphorylation site. WB:WBGene00009887 glb-17 Predicted to enable heme binding activity and oxygen binding activity. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00009888 F49E2.5 Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. WB:WBGene00009889 F49E11.2 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00009890 scl-9 Predicted to be located in extracellular space. Is an ortholog of several human genes including CRISPLD1 (cysteine rich secretory protein LCCL domain containing 1); GLIPR1 (GLI pathogenesis related 1); and PI15 (peptidase inhibitor 15). WB:WBGene00009891 scl-10 Predicted to be located in extracellular space. Is an ortholog of several human genes including CRISPLD1 (cysteine rich secretory protein LCCL domain containing 1); GLIPR1 (GLI pathogenesis related 1); and PI15 (peptidase inhibitor 15). WB:WBGene00009892 scl-11 Predicted to be located in extracellular space. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00009893 F49E11.7 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00009894 F49E11.8 Enriched in NSM based on tiling array studies. Is affected by rsr-2; hpl-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00009895 scl-2 Predicted to be located in extracellular space. Expressed in intestinal cell. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00009896 scl-3 Predicted to be located in extracellular space. Expressed in g1AL; g1AR; g1P; g2L; and g2R. Is an ortholog of human GLIPR1 (GLI pathogenesis related 1) and R3HDML (R3H domain containing like). WB:WBGene00009897 skpo-1 Enables peroxidase activity. Involved in defense response to Gram-positive bacterium; determination of adult lifespan; and negative regulation of gene expression. Predicted to be located in extracellular space. WB:WBGene00009898 dod-23 Enriched in germ line; intestine; pharyngeal muscle cell; and pharyngeal-intestinal valve based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by twenty-eight chemicals including aldicarb; Ethanol; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00009899 efl-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Expressed in VA neuron; VB neuron; head neurons; and ventral nerve cord. Is an ortholog of human E2F8 (E2F transcription factor 8). WB:WBGene00009900 F49E12.7 Predicted to be located in membrane. WB:WBGene00009901 F49E12.8 Enriched in neurons and spermatheca based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009902 drd-1 Predicted to enable C-4 methylsterol oxidase activity. Predicted to be involved in sterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human FAXDC2 (fatty acid hydroxylase domain containing 2). WB:WBGene00009903 F49E12.10 Predicted to enable C-4 methylsterol oxidase activity. Predicted to be involved in sterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human FAXDC2 (fatty acid hydroxylase domain containing 2). WB:WBGene00009904 F49E12.12 Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00009905 clec-240 Is affected by several genes including let-60; eat-2; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Mercuric Chloride; Tunicamycin; and Cry5B based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00009906 clec-241 Is affected by several genes including sir-2.1; mut-2; and qui-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Testosterone; Atrazine; and fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00009907 F49H6.3 Predicted to be located in membrane. WB:WBGene00009908 F49H6.5 Predicted to enable GTP 3',8'-cyclase activity and cyclic pyranopterin monophosphate synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Predicted to be part of molybdopterin synthase complex. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type A. Is an ortholog of human MOCS1 (molybdenum cofactor synthesis 1). WB:WBGene00009909 F49H6.8 Is affected by several genes including eat-2; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00009910 srz-92 Is affected by etr-1 and let-60 based on RNA-seq and microarray studies. Is affected by dafa#1 and Sirolimus based on microarray studies. WB:WBGene00009911 srz-93 No description available WB:WBGene00009912 srz-94 Predicted to be located in membrane. Expressed in muscle cell. WB:WBGene00009913 F49H6.12 Is affected by mir-34 and eat-2 based on microarray studies. Is affected by Mercuric Chloride and Sirolimus based on microarray studies. WB:WBGene00009914 F49H6.13 Predicted to be located in membrane. WB:WBGene00009915 F52A8.1 Predicted to be located in membrane. WB:WBGene00009916 F52A8.3 Predicted to be located in membrane. WB:WBGene00009917 glb-18 Predicted to enable heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Located in endoplasmic reticulum. Expressed in ventral nerve cord. WB:WBGene00009918 gcsh-2 Predicted to be involved in glycine decarboxylation via glycine cleavage system. Predicted to be located in mitochondrion. Predicted to be part of glycine cleavage complex. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and multiple mitochondrial dysfunctions syndrome. Is an ortholog of human GCSH (glycine cleavage system protein H). WB:WBGene00009919 kbrl-1 Predicted to enable GTPase activating protein binding activity. Predicted to be involved in Ral protein signal transduction. Expressed in head. Is an ortholog of human NKIRAS1 (NFKB inhibitor interacting Ras like 1) and NKIRAS2 (NFKB inhibitor interacting Ras like 2). WB:WBGene00009920 abts-1 Enables chloride transmembrane transporter activity and solute:inorganic anion antiporter activity. Involved in several processes, including cholinergic synaptic transmission; regulation of GABAergic synaptic transmission; and response to serotonin. Predicted to be located in plasma membrane. Expressed in HSN; accessory cell; body wall musculature; head; and pharynx. Human ortholog(s) of this gene implicated in cholangiocarcinoma and renal tubular acidosis. Is an ortholog of human SLC4A10 (solute carrier family 4 member 10); SLC4A7 (solute carrier family 4 member 7); and SLC4A8 (solute carrier family 4 member 8). WB:WBGene00009921 F52B5.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cilium assembly; intracellular signal transduction; and intraciliary transport. Predicted to be located in cilium; cytoplasm; and nucleus. WB:WBGene00009922 F52B5.3 Predicted to enable RNA binding activity and helicase activity. Is an ortholog of human YTHDC2 (YTH N6-methyladenosine RNA binding protein C2). WB:WBGene00009923 F52B5.7 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalaappppa; g2; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by twelve chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Zinc finger C2H2 superfamily and Phosphorylation site. WB:WBGene00009924 cfp-1 Predicted to enable methylated histone binding activity. Involved in transdifferentiation. Predicted to be located in nucleus. Predicted to be part of Set1C/COMPASS complex. Is an ortholog of human CXXC1 (CXXC finger protein 1). WB:WBGene00009925 F52B11.2 Predicted to enable phosphomannomutase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ia. Is an ortholog of human PMM1 (phosphomannomutase 1) and PMM2 (phosphomannomutase 2). WB:WBGene00009926 noah-2 Involved in molting cycle. Predicted to be located in membrane. WB:WBGene00009927 F52B11.5 Enriched in several structures, including ABplppaaaap; ABprppaaaap; head mesodermal cell; intestine; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and pmk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00009929 abts-2 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic ion homeostasis and transmembrane transport. Located in basolateral plasma membrane. Expressed in dorsal-rectal ganglion neurons; gonadal sheath cell; and tail neurons. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy; congenital hereditary endothelial dystrophy of cornea; and corneal dystrophy-perceptive deafness syndrome. Is an ortholog of human SLC4A11 (solute carrier family 4 member 11). WB:WBGene00009930 F52D10.2 Expressed in head and tail. Is predicted to encode a protein with the following domains: PH-like domain superfamily; Phosphotyrosine interaction domain (PTB/PID); and PTB/PI domain. Is an ortholog of human FAM43B (family with sequence similarity 43 member B). WB:WBGene00009931 F52D10.4 Predicted to be located in membrane. WB:WBGene00009933 F52E10.2 Is affected by several genes including mex-3; ifg-1; and sams-3 based on tiling array; microarray; and RNA-seq studies. Is affected by Tunicamycin based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00009935 F52E10.4 Enriched in several structures, including ABplpaaaaa; ABplpaappa; ABplppppaa; ALM; and BDU based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009936 C02D4.t1 Is affected by hmg-3 and adr-1 based on RNA-seq studies. WB:WBGene00009937 lsl-1 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Expressed in Z2; Z3; and germ cell. WB:WBGene00009938 F52F12.5 Enriched in several structures, including ABalapaaaa; ABalappapa; ABarpapaaa; ABarpapaapp; and AVL based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-three chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00009939 ztf-11 Predicted to enable zinc ion binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; neuron differentiation; and positive regulation of cell differentiation. Located in nucleus. Expressed in g1 and head neurons. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 39. Is an ortholog of human MYT1L (myelin transcription factor 1 like). WB:WBGene00009940 strl-1 Predicted to enable lipid binding activity. Predicted to be involved in vesicle tethering to endoplasmic reticulum. Predicted to be located in endoplasmic reticulum membrane; endoplasmic reticulum-endosome membrane contact site; and late endosome membrane. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia. Is an ortholog of human STAR (steroidogenic acute regulatory protein). WB:WBGene00009941 F52F12.8 Predicted to be located in cytoskeleton. WB:WBGene00009942 F52F12.9 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. WB:WBGene00009943 F52G2.3 Enriched in several structures, including ABaraapapaa; ABaraapppaa; RID; head mesodermal cell; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: RSD-2, N-terminal; RSD-2 N-terminal domain; and Phosphorylation site. WB:WBGene00009944 mtcu-2 Predicted to enable flavin adenine dinucleotide binding activity. Predicted to be involved in mitochondrial tRNA wobble uridine modification and tRNA methylation. Predicted to be located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 10. Is an ortholog of human MTO1 (mitochondrial tRNA translation optimization 1). WB:WBGene00009945 bath-38 Expressed in several structures, including hypodermis and pharynx. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00009946 ogr-2 Expressed in gonad. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00009947 ttc-36 Predicted to be involved in cilium assembly. Is an ortholog of human TTC36 (tetratricopeptide repeat domain 36). WB:WBGene00009948 F52H3.6 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00009949 F53A2.1 Predicted to be located in membrane. WB:WBGene00009950 sdz-20 Predicted to be located in membrane. WB:WBGene00009951 F53A2.3 Enriched in several structures, including ABalapppaa; ABalpppappp; ABalppppaa; head motor neurons; and interneuron based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nine chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00009952 acaa-2 Predicted to enable acetyl-CoA C-acetyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Is an ortholog of human ACAA2 (acetyl-CoA acyltransferase 2). WB:WBGene00009953 F53A2.9 Enriched in several structures, including ABarpapaaa; body muscle cell; excretory cell; neurons; and rectum based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by fifteen chemicals including hydrogen sulfide; rotenone; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00009954 F53B2.1 Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on proteomic; microarray; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00009955 eak-4 Involved in dauer larval development. Located in plasma membrane. Expressed in XXXL and XXXR. WB:WBGene00009956 F53B2.5 Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be located in nucleoplasm. WB:WBGene00009957 F53B2.8 Enriched in several structures, including ABalpappaa; ABprpapppa; head mesodermal cell; rectal gland cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirty-six chemicals including Ethanol; Nitric Oxide; and 1-methylnicotinamide based on RNA-seq and microarray studies. WB:WBGene00009958 madd-4 Enables signaling receptor binding activity. Involved in dorsal/ventral axon guidance and synapse organization. Located in extracellular space. Expressed in blast cell; neurons; and somatic nervous system. Is an ortholog of human ADAMTS12 (ADAM metallopeptidase with thrombospondin type 1 motif 12); ADAMTSL1 (ADAMTS like 1); and ADAMTSL3 (ADAMTS like 3). WB:WBGene00009959 F53B6.4 Predicted to be located in cytoskeleton and membrane. WB:WBGene00009960 F53B6.5 Predicted to enable aminopeptidase activity and metalloexopeptidase activity. Predicted to be located in cytoplasm. Is an ortholog of human METAP2 (methionyl aminopeptidase 2). WB:WBGene00009961 cutl-7 Predicted to be located in membrane. WB:WBGene00009962 F53B6.7 Enriched in OLL; PVD; germ line; and in male based on proteomic; microarray; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Histidine phosphatase superfamily (branch 1); Histidine phosphatase superfamily; and Histidine phosphatase superfamily, clade-1. WB:WBGene00009963 fipr-26 Enriched in several structures, including ABalaapppp; ABalapaapp; ABalappppa; cephalic sheath cell; and excretory cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty-one chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00009964 fip-6 Enriched in AWA; germline precursor cell; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including Nitric Oxide; methylmercury hydroxide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00009965 frpr-9 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00009966 isy-1 Involved in regulation of primary miRNA processing. Located in nucleus. Expressed in several structures, including hypodermis and neurons. Is an ortholog of human ISY1 (ISY1 splicing factor homolog) and ISY1-RAB43 (ISY1-RAB43 readthrough). WB:WBGene00009967 F53B7.4 Predicted to be located in membrane. WB:WBGene00009968 fig-1 Predicted to be located in membrane. Expressed in amphid sheath cell and phasmid sheath cell. WB:WBGene00009969 F53B7.7 Enriched in several structures, including excretory cell; intestine; muscle cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009971 F53C11.1 Located in membrane raft. WB:WBGene00009972 oac-33 Enriched in muscle cell based on microarray studies. Is affected by several genes including eat-2; pgl-1; and nhr-49 based on RNA-seq and microarray studies. Is affected by five chemicals including 1-methylnicotinamide; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00009973 decr-1.1 Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in mitochondrion. Is an ortholog of human DECR1 (2,4-dienoyl-CoA reductase 1). WB:WBGene00009974 F53C11.4 Enriched in arc ant V; germ line; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including bisphenol S; Alovudine; and Zidovudine based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00009975 F53C11.5 Enriched in several structures, including ABalapppaa; ABarpapaapp; ABplaaaaapp; germ line; and neurons based on Chronogram; microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00009976 swan-2 Involved in response to heat and response to osmotic stress. Predicted to be located in nucleus. Expressed in head. Is an ortholog of human DCAF7 (DDB1 and CUL4 associated factor 7). WB:WBGene00009977 swan-1 Enables LIM domain binding activity and small GTPase binding activity. Involved in several processes, including regulation of cellular component organization; response to heat; and response to osmotic stress. Located in cytoplasm. Expressed in several structures, including neuroblasts and neurons. Is an ortholog of human DCAF7 (DDB1 and CUL4 associated factor 7). WB:WBGene00009978 F53E4.1 Predicted to enable chromatin binding activity. Predicted to be located in cytoplasm. Expressed in tail. Is an ortholog of human KLHDC3 (kelch domain containing 3). WB:WBGene00009979 cutl-1 Predicted to be located in membrane. WB:WBGene00009980 F53F1.2 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. WB:WBGene00009981 F53F1.3 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. WB:WBGene00009982 F53F1.4 Enriched in carbon dioxide sensory neurons; germline precursor cell; hypodermis; and rectal epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by thirty-two chemicals including aldicarb; 1-methylnicotinamide; and nicotinic acid based on microarray and RNA-seq studies. WB:WBGene00009983 cut-2 Predicted to be a structural constituent of cuticle. Predicted to be located in extracellular region. WB:WBGene00009984 F53F1.6 Enriched in body wall muscle cell; coelomocyte; germline precursor cell; and intestine based on tiling array; proteomic; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00009985 F53F4.1 Enriched in GABAergic neurons; amphid sheath cell; excretory cell; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray; RNA-seq; and tiling array studies. Is affected by four chemicals including cholesterol; bortezomib; and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00009986 F53F4.2 Enriched in I6 neuron based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; elt-2; and aak-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00009987 tbcb-1 Predicted to be located in cytoplasm and microtubule. Is an ortholog of human TBCB (tubulin folding cofactor B). WB:WBGene00009988 F53F4.4 Enriched in ABplapapppp; ABprapapppp; CAN; rectal epithelial cell; and touch receptor neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00009990 F53F4.7 Predicted to enable transferase activity. WB:WBGene00009991 F53F4.8 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00009992 nduv-2 Predicted to enable 2 iron, 2 sulfur cluster binding activity; NADH dehydrogenase (ubiquinone) activity; and metal ion binding activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in Parkinson's disease and nuclear type mitochondrial complex I deficiency 7. Is an ortholog of human NDUFV2 (NADH:ubiquinone oxidoreductase core subunit V2). WB:WBGene00009993 F53F4.11 Enriched in several structures, including ABplaapaap; ABpraapaap; M cell; germ line; and somatic gonad precursor based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Human RSL1D1 enables mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Is predicted to encode a protein with the following domains: Large ribosomal subunit protein uL1, 3-layer alpha/beta-sandwich domain; Ribosomal protein uL1/ribosomal biogenesis protein; Ribosomal protein L1p/L10e family; Ribosomal protein uL1-like; and Phosphorylation site. Is an ortholog of human RSL1D1 (ribosomal L1 domain containing 1). WB:WBGene00009994 F53F4.12 Enriched in AVK; body wall muscle cell; germ line; intestine; and mechanosensory neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on RNA-seq and microarray studies. Is affected by four chemicals including Zidovudine; paraquat; and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00009995 spig-9 Expressed in amphid sheath cell and phasmid sheath cell. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473; Domain of unknown function (DUF4473); and Phosphorylation site. WB:WBGene00009996 sde-2 Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in RNA splicing; cell division; and mRNA processing. Predicted to be located in nucleus. Is an ortholog of human SDE2 (SDE2 telomere maintenance homolog). WB:WBGene00009997 F53F4.15 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00009998 klf-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of gene expression and regulation of lipid metabolic process. Predicted to be located in nucleus. Expressed in intestine. Human ortholog(s) of this gene implicated in intracranial aneurysm. Is an ortholog of human KLF5 (KLF transcription factor 5). WB:WBGene00009999 srsx-35 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of several human genes including OR2M4 (olfactory receptor family 2 subfamily M member 4); OR5H1 (olfactory receptor family 5 subfamily H member 1); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00010000 F53F8.3 Predicted to enable metal ion binding activity. WB:WBGene00010001 F53F8.4 Enriched in several structures, including ABplapaaapa; ABprapaaapa; AIZ; germline precursor cell; and intestine based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB; DB module; and Phosphorylation site. WB:WBGene00010002 F53F8.5 Predicted to be located in nucleus. Is an ortholog of human C19orf47 (chromosome 19 open reading frame 47). WB:WBGene00010003 F53F8.6 Predicted to be located in membrane. WB:WBGene00010004 F53H2.1 Enriched in ABalaaaala; ABalaapaaa; intestine; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Sirolimus; multi-walled carbon nanotube; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF713) and Protein of unknown function DUF713. WB:WBGene00010005 cnc-7 Predicted to be located in membrane. WB:WBGene00010006 F53H2.3 Expressed in gonad and intestine. WB:WBGene00010007 F53H4.2 Enriched in GABAergic neurons; amphid sheath cell; anterior spermatheca; and posterior spermatheca based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including aldicarb; Ethanol; and 1-methylnicotinamide based on microarray; RNA-seq; and proteomic studies. WB:WBGene00010008 F53H4.3 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00010009 F53H4.4 Enriched in muscle cell; neurons; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including Cry5B; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00010010 gmeb-2 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and metal ion binding activity. Predicted to be involved in DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Is an ortholog of human GMEB1 (glucocorticoid modulatory element binding protein 1) and GMEB2 (glucocorticoid modulatory element binding protein 2). WB:WBGene00010011 F53H4.6 Predicted to enable ATP-dependent activity, acting on DNA. Predicted to be involved in transcription-coupled nucleotide-excision repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including Cockayne syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human ERCC6 (ERCC excision repair 6, chromatin remodeling factor). WB:WBGene00010012 saeg-1 Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Located in nucleus. Is an ortholog of human MIDEAS (mitotic deacetylase associated SANT domain protein); TRERF1 (transcriptional regulating factor 1); and ZNF541 (zinc finger protein 541). WB:WBGene00010013 F54B3.1 Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 18. Is an ortholog of human SZT2 (SZT2 subunit of KICSTOR complex). WB:WBGene00010014 F54B3.2 Predicted to be located in membrane. WB:WBGene00010015 atad-3 Predicted to enable ATP binding activity and ATP hydrolysis activity. Involved in mitochondrion organization. Located in mitochondrion. Is an ortholog of human ATAD3A (ATPase family AAA domain containing 3A) and ATAD3B (ATPase family AAA domain containing 3B). WB:WBGene00010016 F54B8.1 Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including pmk-1; clk-1; and aak-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Cadmium Chloride; silicon dioxide nanoparticle; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00010017 nhr-282 Predicted to be located in nucleus. WB:WBGene00010018 fbxa-69 Enriched in several structures, including dopaminergic neurons; g1P; male distal tip cell; sensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including rotenone; manganese chloride; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00010019 F54B8.4 Predicted to enable death domain binding activity. Involved in innate immune response. Is an ortholog of human DAP (death associated protein). WB:WBGene00010020 srbc-48 Predicted to be located in membrane. Expressed in AWCL; AWCR; and head neurons. WB:WBGene00010021 srbc-49 Predicted to be located in membrane. WB:WBGene00010022 srbc-50 Predicted to be located in membrane. WB:WBGene00010023 srbc-51 Predicted to be located in membrane. WB:WBGene00010024 srbc-52 Expressed in PVT. WB:WBGene00010025 srbc-54 Predicted to be located in membrane. WB:WBGene00010026 srbc-56 Predicted to be located in membrane. WB:WBGene00010027 F54B11.4 Enriched in ALML; ALMR; PLML; PLMR; and RID based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00010028 F54B11.5 Predicted to enable metal ion binding activity. Is an ortholog of human RNF141 (ring finger protein 141). WB:WBGene00010030 F54B11.7 Enriched in I5 neuron based on single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00010031 F54B11.8 Enriched in Z1.p; Z4.a; male distal tip cell; muscle cell; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00010032 F54B11.9 Enriched in ALM; GABAergic neurons; PLM; body wall muscle cell; and muscle cell based on tiling array; microarray; and RNA-seq studies. Is affected by several genes including skn-1; daf-12; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including 1-methylnicotinamide; D-glucose; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00010033 F54B11.10 Enriched in several structures, including ABalppppapa; ABplaapaaa; NSM; PLM; and amphid neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; pmk-1; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including methylmercury hydroxide; 1-methylnicotinamide; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00010034 F54B11.11 Predicted to be involved in innate immune response. WB:WBGene00010035 F54C8.1 Predicted to enable 3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 4. Is an ortholog of human HADH (hydroxyacyl-CoA dehydrogenase). WB:WBGene00010036 cpar-1 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in mitotic sister chromatid segregation. Located in condensed chromosome and nucleus. WB:WBGene00010037 pir-2 Predicted to enable polynucleotide 5'-phosphatase activity. Predicted to be involved in dephosphorylation. Expressed in AB and pharynx. Is an ortholog of human DUSP11 (dual specificity phosphatase 11). WB:WBGene00010038 rheb-1 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in positive regulation of TOR signaling and small GTPase mediated signal transduction. Predicted to be located in plasma membrane. Expressed in head neurons; hypodermis; tail neurons; and vulval muscle. Is an ortholog of human RHEB (Ras homolog, mTORC1 binding). WB:WBGene00010039 F54C8.6 Predicted to be located in membrane. WB:WBGene00010040 F54C8.7 Predicted to enable phospholipid binding activity. Involved in IRE1-mediated unfolded protein response. Located in mitochondrion. Is an ortholog of human ARFIP1 (ADP ribosylation factor interacting protein 1) and ARFIP2 (ADP ribosylation factor interacting protein 2). WB:WBGene00010041 F54C9.3 Enriched in several structures, including ABaraapapaa; ABaraapppaa; AFD; head mesodermal cell; and lateral ganglion based on tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by nineteen chemicals including hydrogen sulfide; 1-methylnicotinamide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010042 bcs-1 Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in mitochondrial respiratory chain complex III assembly and protein insertion into mitochondrial inner membrane from matrix. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Bjornstad syndrome; GRACILE syndrome; and mitochondrial complex III deficiency nuclear type 1. Is an ortholog of human BCS1L (BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone). WB:WBGene00010043 F54C9.7 Involved in negative regulation of fatty acid transport; regulation of lipid storage; and regulation of peptide transport. Predicted to be located in membrane. Expressed in excretory cell; hypodermis; intestinal cell; and pharyngeal muscle cell. WB:WBGene00010044 F54C9.9 Predicted to be involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of 90S preribosome. Is an ortholog of human KRI1 (KRI1 homolog). WB:WBGene00010045 F54C9.11 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in exocytosis. Predicted to be located in Golgi to plasma membrane transport vesicle. Expressed in hypodermis; vulA; vulB1; vulB2; and vulval muscle. Is an ortholog of human RAB3IL1 (RAB3A interacting protein like 1) and RAB3IP (RAB3A interacting protein). WB:WBGene00010046 F54D1.1 Predicted to enable mRNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. WB:WBGene00010047 F54D1.6 Predicted to be involved in cell-matrix adhesion. Predicted to be located in extracellular space. WB:WBGene00010048 F54D5.2 Enriched in several structures, including FLP; germ line; germline precursor cell; head mesodermal cell; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00010049 F54D5.3 Enriched in head mesodermal cell; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including rotenone; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Family of unknown function (DUF5352) and Protein of unknown function DUF5352. WB:WBGene00010050 F54D5.4 Involved in innate immune response. WB:WBGene00010051 F54D5.5 Enriched in several structures, including ABalappaap; ABalpapaap; ciliated neurons; germ line; and pharyngeal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; Cry5B; and glycine based on microarray and RNA-seq studies. WB:WBGene00010052 F54D5.7 Predicted to enable fatty-acyl-CoA binding activity; flavin adenine dinucleotide binding activity; and glutaryl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase and fatty-acyl-CoA biosynthetic process. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in glutaric acidemia I. Is an ortholog of human GCDH (glutaryl-CoA dehydrogenase). WB:WBGene00010053 F54D5.9 Enriched in several structures, including ABalppppaa; ABaraapapp; AVK; amphid neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: F-box only protein 47. Is an ortholog of human FBXO47 (F-box protein 47). WB:WBGene00010054 gtf-2E2 Enables RNA polymerase II complex binding activity. Involved in transcription initiation at RNA polymerase II promoter. Part of transcription factor TFIIE complex. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 6. Is an ortholog of human GTF2E2 (general transcription factor IIE subunit 2). WB:WBGene00010055 dhgd-1 Predicted to enable catalytic activity and flavin adenine dinucleotide binding activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in D-2-hydroxyglutaric aciduria 1. Is an ortholog of human D2HGDH (D-2-hydroxyglutarate dehydrogenase). WB:WBGene00010056 smc-6 Predicted to enable damaged DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination. Located in condensed nuclear chromosome and nucleoplasm. Is an ortholog of human SMC6 (structural maintenance of chromosomes 6). WB:WBGene00010057 F54D5.15 Enriched in GABAergic neurons; MSaaaaapa; and pharyngeal muscle cell based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by six chemicals including stavudine; Zidovudine; and Oligosaccharides based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010058 F54E4.2 Predicted to be located in membrane. WB:WBGene00010059 F54E4.3 Enriched in several structures, including ABalppppapa; head mesodermal cell; neuronal sheath cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq; microarray; and proteomic studies. Is affected by fourteen chemicals including aldicarb; iron oxide nanoparticle; and stavudine based on microarray and RNA-seq studies. WB:WBGene00010060 F54E4.4 Expressed in AIYL and AIYR. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00010061 F54E12.2 Predicted to enable ATP-dependent activity, acting on DNA. Predicted to be involved in DNA repair. Predicted to be located in nucleus. Is an ortholog of human TTF2 (transcription termination factor 2). WB:WBGene00010062 lipl-1 Predicted to enable hydrolase activity, acting on ester bonds. Involved in lipid catabolic process. Located in lysosome. Expressed in intestine. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). WB:WBGene00010063 dhrs-4 Enables carbonyl reductase (NADPH) activity. WB:WBGene00010064 F54F7.2 Enriched in AVK; AVKL; AVKR; coelomocyte; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00010065 F54F7.3 Enriched in AVG; RIM; amphid sheath cell; command interneuron; and spermatheca based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including Ethanol; rotenone; and sodium arsenite based on RNA-seq; microarray; and proteomic studies. WB:WBGene00010066 F54F7.6 Predicted to be located in membrane. WB:WBGene00010067 dot-1.2 Predicted to enable histone H3K79 methyltransferase activity. Predicted to be involved in DNA damage checkpoint signaling and DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in acute biphenotypic leukemia. Is an ortholog of human DOT1L (DOT1 like histone lysine methyltransferase). WB:WBGene00010068 F54F7.8 Enriched in DB neuron and coelomocyte based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including tryptophan; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00010069 F54F11.1 Predicted to enable hydrolase activity, acting on ester bonds. Expressed in pharyngeal gland cell. WB:WBGene00010070 nep-17 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Located in membrane raft. Expressed in intestine. WB:WBGene00010071 sre-45 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00010072 F54F12.1 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00010073 F54F12.2 Predicted to be located in membrane. WB:WBGene00010074 irld-34 Enriched in GLR; muscle cell; neurons; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including alg-1; daf-19; and dpy-21 based on microarray and RNA-seq studies. Is affected by five chemicals including Tunicamycin; resveratrol; and Chlorpyrifos based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00010075 F55A11.1 Predicted to enable calcium ion binding activity. Is an ortholog of human MCFD2 (multiple coagulation factor deficiency 2, ER cargo receptor complex subunit). WB:WBGene00010077 F55A11.4 Predicted to enable calcium ion binding activity. Predicted to be involved in transmembrane transport. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human SLC25A25 (solute carrier family 25 member 25). WB:WBGene00010079 F55A11.6 Enriched in several structures, including coelomocyte; germ line; head mesodermal cell; sensory neurons; and tail precursor cell based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; microarray; proteomic; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal domain; and Glutathione S-transferase, C-terminal. WB:WBGene00010080 F55A11.7 Predicted to be located in membrane. WB:WBGene00010081 F55A11.8 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00010082 F55A11.11 Enriched in head mesodermal cell and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Histidine phosphatase superfamily (branch 1); Histidine phosphatase superfamily; Histidine phosphatase superfamily, clade-1; and Phosphorylation site. WB:WBGene00010083 xdh-1 Predicted to enable oxidoreductase activity. Predicted to be located in peroxisome. Expressed in excretory cell and head neurons. Human ortholog(s) of this gene implicated in several diseases, including Lesch-Nyhan syndrome; artery disease (multiple); and laryngeal squamous cell carcinoma. Is an ortholog of human XDH (xanthine dehydrogenase). WB:WBGene00010084 F55B11.2 Enriched in AVK; anterior spermatheca; germ line; and posterior spermatheca based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-two chemicals including Ethanol; 1-methylnicotinamide; and rotenone based on RNA-seq; proteomic; and microarray studies. WB:WBGene00010085 F55B11.3 Enriched in anterior spermatheca; dopaminergic neurons; germ line; and posterior spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq; microarray; and proteomic studies. WB:WBGene00010086 F55B11.4 Enriched in several structures, including ALN; head mesodermal cell; mechanosensory neurons; pharyngeal muscle cell; and rectal epithelium based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including rotenone; D-glucopyranose; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00010087 F55B11.5 Enriched in germ line based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and pmk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including aldicarb; Ethanol; and Rifampin based on microarray; RNA-seq; and proteomic studies. WB:WBGene00010088 F55B12.2 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00010089 hpo-31 Predicted to enable tRNA binding activity. Predicted to be involved in mitochondrial tRNA 3'-end processing and tRNA 3'-terminal CCA addition. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Is an ortholog of human TRNT1 (tRNA nucleotidyl transferase 1). WB:WBGene00010091 ssp-35 Enriched in coelomocyte; germ line; sperm; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-two chemicals including Ethanol; nicotinic acid; and rotenone based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00010092 F55C5.2 Enriched in coelomocyte; germ line; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00010093 capg-2 Involved in mitotic sister chromatid segregation. Predicted to be located in nucleus. Predicted to be part of condensin complex. Is an ortholog of human NCAPG2 (non-SMC condensin II complex subunit G2). WB:WBGene00010094 tsfm-1 Predicted to enable translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 3. Is an ortholog of human TSFM (Ts translation elongation factor, mitochondrial). WB:WBGene00010095 F55C5.6 Enriched in DA neuron and VA neuron based on tiling array studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00010096 rskd-1 Predicted to enable ATP binding activity; phosphatidylinositol binding activity; and protein kinase activity. Expressed in GABAergic neurons; rectal muscle; retrovesicular ganglion; and somatic nervous system. Is an ortholog of human RPS6KC1 (ribosomal protein S6 kinase C1). WB:WBGene00010097 srpa-68 Predicted to enable signal recognition particle binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in endoplasmic reticulum and nucleolus. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is an ortholog of human SRP68 (signal recognition particle 68). WB:WBGene00010098 F55C5.10 Enriched in MC neuron; MCL; MCR; and pharyngeal-intestinal valve based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00010099 fbxb-117 Enriched in ABalapppaa; SIA; and rect_D based on single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Mercuric Chloride; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00010100 F55C9.3 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; anterior hypodermis; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: PAZ domain superfamily. WB:WBGene00010101 fbxb-57 Enriched in ABplpapapa; ABprpapapa; G2; and W cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00010102 F55C9.5 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and anterior hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including Mercuric Chloride; multi-walled carbon nanotube; and metformin based on microarray and RNA-seq studies. WB:WBGene00010103 F55C9.6 Is affected by several genes including eat-2; sir-2.1; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00010104 fbxb-60 Enriched in several structures, including ABalppappa; ABarappppa; ABplpaappa; ALA; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00010105 fbxb-62 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalpapaap; ABarappaap; and amphid neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00010106 fbxb-61 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalppappa; ABarappppa; and ABplapaaaa based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; indole; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00010107 F55C9.11 Is affected by spn-4; tdc-1; and mrps-5 based on RNA-seq and microarray studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00010108 F55C10.4 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00010109 F55C10.5 Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to be involved in regulation of phosphorylation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in stomach cancer. Is an ortholog of several human genes including PPP1R14B (protein phosphatase 1 regulatory inhibitor subunit 14B); PPP1R14C (protein phosphatase 1 regulatory inhibitor subunit 14C); and PPP1R14D (protein phosphatase 1 regulatory inhibitor subunit 14D). WB:WBGene00010110 F55D12.1 Predicted to be located in membrane. WB:WBGene00010111 F55D12.2 Predicted to enable phosphatidylinositol phosphate binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Is an ortholog of human SESTD1 (SEC14 and spectrin domain containing 1). WB:WBGene00010112 nhr-191 Is affected by several genes including sir-2.1; cyc-1; and adr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Atrazine based on microarray studies. WB:WBGene00010113 F55D12.5 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00010114 F55D12.6 Predicted to be located in membrane. WB:WBGene00010115 aakb-1 Predicted to enable protein kinase binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleotide-activated protein kinase complex. Expressed in body wall musculature; neurons; non-striated muscle; rectal valve cell; and tail hypodermis. Is an ortholog of human PRKAB1 (protein kinase AMP-activated non-catalytic subunit beta 1) and PRKAB2 (protein kinase AMP-activated non-catalytic subunit beta 2). WB:WBGene00010116 cest-13 Predicted to enable carboxylic ester hydrolase activity. WB:WBGene00010117 nkb-3 Predicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Human ortholog(s) of this gene implicated in essential hypertension. Is an ortholog of several human genes including ATP1B1 (ATPase Na+/K+ transporting subunit beta 1); ATP1B2 (ATPase Na+/K+ transporting subunit beta 2); and ATP1B3 (ATPase Na+/K+ transporting subunit beta 3). WB:WBGene00010118 F55F3.4 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; manganese chloride; and stavudine based on microarray and RNA-seq studies. WB:WBGene00010119 F55G7.1 Enriched in ABalpapaap; ABarappaap; ABplapaaaa; ABprapaaaa; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00010120 dot-1.4 Predicted to enable histone H3K79 methyltransferase activity. Predicted to be involved in DNA damage checkpoint signaling and DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in acute biphenotypic leukemia. Is an ortholog of human DOT1L (DOT1 like histone lysine methyltransferase). WB:WBGene00010121 F55G7.3 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by csr-1; alg-1; and etr-1 based on RNA-seq studies. Is affected by tryptophan based on microarray studies. WB:WBGene00010122 F55G11.1 Predicted to be located in membrane. WB:WBGene00010123 F55G11.2 Involved in innate immune response. WB:WBGene00010124 F55G11.4 Involved in defense response to Gram-negative bacterium. Expressed in intestine. WB:WBGene00010125 dod-22 Involved in defense response to Gram-negative bacterium and innate immune response. Expressed in head neurons and rectal gland cell. WB:WBGene00010126 F55G11.6 Is affected by several genes including skn-1; daf-12; and sir-2.1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by ten chemicals including Mercuric Chloride; Tunicamycin; and sodium arsenite based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00010127 F55G11.7 Involved in innate immune response. Expressed in amphid neurons; head neurons; intestine; phasmid neurons; and rectal gland cell. WB:WBGene00010128 F55G11.8 Involved in innate immune response. WB:WBGene00010129 F55G11.10 Enriched in male based on RNA-seq studies. Is affected by several genes including sir-2.1; dpy-21; and mut-2 based on tiling array; RNA-seq; and microarray studies. Is affected by estrogen; Atrazine; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00010130 vha-14 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to contribute to P-type proton-exporting transporter activity. Predicted to be involved in regulation of intracellular pH. Predicted to be part of proton-transporting V-type ATPase complex. Is an ortholog of human ATP6V1D (ATPase H+ transporting V1 subunit D). WB:WBGene00010131 F55H2.5 Predicted to enable transmembrane monodehydroascorbate reductase activity. Predicted to be involved in ascorbate homeostasis. Predicted to be located in membrane. Is an ortholog of human CYB561 (cytochrome b561). WB:WBGene00010132 F55H2.7 Enriched in C; germ line; intestine; neurons; and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00010133 F55H12.2 Enriched in PLM; carbon dioxide sensory neurons; coelomocyte; germline precursor cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including diallyl trisulfide; hydrogen sulfide; and Ethanol based on microarray and RNA-seq studies. WB:WBGene00010134 F55H12.3 Predicted to enable Notch binding activity. Predicted to be located in membrane. WB:WBGene00010135 F55H12.4 Expressed in anus; hypodermis; pharynx; and vulva. WB:WBGene00010136 spe-54 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00010137 ztf-26 Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Expressed in head muscle; head neurons; hypodermis; nerve ring neurons; and ventral nerve cord. WB:WBGene00010138 anoh-1 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Expressed in intestine; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Miyoshi muscular dystrophy 3; Scott syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; bone disease (multiple); and dystonia 24. Is an ortholog of human ANO6 (anoctamin 6). WB:WBGene00010139 F56A8.3 Predicted to be located in membrane. Expressed in intestine; neurons; pharynx; and rectal gland cell. Is an ortholog of human LRRC59 (leucine rich repeat containing 59). WB:WBGene00010140 F56A8.4 Enriched in several structures, including ABalaapppa; ABalapaaaa; AFD; body wall musculature; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; stavudine; and antimycin based on RNA-seq and microarray studies. WB:WBGene00010141 F56A8.5 Enriched in several structures, including ABalapaaaa; ABalappapa; AFD; GLR; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and lin-35 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00010142 F56A8.8 Enriched in AVK; FLP; arcade cell; and head ganglion based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Mercuric Chloride; allantoin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00010143 npr-43 Predicted to be located in membrane. WB:WBGene00010144 F56C4.1 Enriched in ABalapppaa; accessory cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; hda-1; and dpy-21 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00010145 F56C4.2 Predicted to be located in membrane. WB:WBGene00010146 glb-19 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in head neurons and tail neurons. WB:WBGene00010147 F56D5.2 Enriched in arc ant V; germ line; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00010148 F56D5.3 Predicted to enable FMN binding activity and oxidoreductase activity. WB:WBGene00010149 F56D5.5 Enriched in MC neuron; germ line; hypodermis; and rect_D based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00010150 F56D5.6 Enriched in coelomocyte; head mesodermal cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010151 F56D5.7 No description available WB:WBGene00010152 F56D5.9 Predicted to be located in membrane. WB:WBGene00010153 srxa-2 Predicted to be located in membrane. WB:WBGene00010155 mstr-2 Predicted to enable zinc ion binding activity. WB:WBGene00010157 oac-34 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00010158 pes-2.2 Enriched in PVR; RIML; and RIMR based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including mianserin; Psoralens; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00010159 wbp-4 Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing. Predicted to be part of precatalytic spliceosome. Is an ortholog of human WBP4 (WW domain binding protein 4). WB:WBGene00010160 png-1 Enables peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity and protein-disulfide reductase (NAD(P)) activity. Involved in cell redox homeostasis; negative regulation of collateral sprouting; and ubiquitin-dependent ERAD pathway. Located in cytoplasm. Expressed in body wall musculature; gonad; neurons; pharynx; and vulva. Human ortholog(s) of this gene implicated in NGLY1-deficiency. Is an ortholog of human NGLY1 (N-glycanase 1). WB:WBGene00010161 F56G4.6 Enriched in several structures, including ABplpaapap; ABplpppaaa; ABprpaapap; ABprpppaaa; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including clk-1; sek-1; and hsp-6 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00010162 F56H6.1 Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be located in membrane. WB:WBGene00010163 F56H6.2 Predicted to be located in membrane. WB:WBGene00010165 F56H6.4 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00010166 gmd-2 Enables GDP-mannose 4,6-dehydratase activity. Involved in GDP-L-fucose biosynthetic process and GDP-mannose metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in open-angle glaucoma. Is an ortholog of human GMDS (GDP-mannose 4,6-dehydratase). WB:WBGene00010167 bgnt-1.6 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including pmk-1; npr-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including tryptophan; Tunicamycin; and allantoin based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A13. Human B4GAT1 enables glucuronosyltransferase activity. Is predicted to encode a protein with the following domain: Glycosyl-transferase for dystroglycan. Is an ortholog of human B4GAT1 (beta-1,4-glucuronyltransferase 1). WB:WBGene00010168 F56H6.7 Predicted to be located in membrane. WB:WBGene00010169 clec-18 Is affected by several genes including daf-2; eat-2; and daf-18 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including resveratrol; Atrazine; and Chlorpyrifos based on microarray studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00010170 F56H6.9 Predicted to be located in membrane. WB:WBGene00010171 oac-35 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00010172 oac-36 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00010173 F56H6.13 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00010174 F56H9.2 Predicted to be located in ribosome. WB:WBGene00010175 F56H11.2 Predicted to be located in membrane. WB:WBGene00010176 F56H11.6 Enriched in several structures, including ABalppppapa; ABpraaapapa; Z1.p; intestine; and male distal tip cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by Atrazine and cadmium based on microarray studies. WB:WBGene00010177 F57A8.1 Expressed widely. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010178 yif-1 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum membrane; and endoplasmic reticulum-Golgi intermediate compartment. Expressed in linker cell. Used to study Parkinson's disease. Is an ortholog of human YIF1A (Yip1 interacting factor homolog A, membrane trafficking protein). WB:WBGene00010179 npr-39 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00010180 nhr-192 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00010181 F57A8.6 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including manganese chloride; D-glucose; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DX and DX module. WB:WBGene00010182 F57A8.7 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00010183 fipr-13 Enriched in body wall muscle cell; dopaminergic neurons; germ line; neurons; and seam cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00010184 F57A10.2 Predicted to be located in cytoskeleton. Expressed in germ line. WB:WBGene00010185 F57A10.4 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. WB:WBGene00010186 nhr-283 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00010187 F57B1.1 Predicted to be located in membrane. WB:WBGene00010188 F57B1.5 Predicted to be located in membrane. WB:WBGene00010189 F57B1.6 Predicted to be located in membrane. WB:WBGene00010191 dmsr-1 Enables neuropeptide receptor activity. Involved in regulation of cellular response to heat and regulation of circadian sleep/wake cycle, sleep. Located in neuronal cell body membrane. Expressed in AIY; RID; and tail neurons. WB:WBGene00010192 F57B7.2 Predicted to be located in extracellular space. WB:WBGene00010193 btb-20 Enriched in NSM; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including manganese chloride; bisphenol S; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00010194 btb-19 Enriched in NSM; Psub1; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including manganese chloride; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00010195 pot-2 Enables G-rich strand telomeric DNA binding activity. Involved in negative regulation of telomere maintenance via telomere lengthening and telomere maintenance. Located in chromosome, telomeric region. WB:WBGene00010196 F57C2.4 Enriched in several structures, including cephalic sheath cell; dopaminergic neurons; excretory cell; germ line; and spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Heme; hydrogen sulfide; and Ethanol based on microarray and RNA-seq studies. WB:WBGene00010197 F57C2.5 Predicted to enable hydrolase activity. Predicted to be involved in biosynthetic process. Located in sarcoplasmic reticulum. Is an ortholog of human APMAP (adipocyte plasma membrane associated protein). WB:WBGene00010198 spat-1 Predicted to enable protein kinase binding activity. Involved in positive regulation of mitotic cell cycle. Located in cytoplasm; kinetochore; and nucleus. Expressed in EMS and P2. Is an ortholog of human BORA (BORA aurora kinase A activator). WB:WBGene00010199 bet-2 Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in chromatin remodeling and regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of chromatin. Human ortholog(s) of this gene implicated in azoospermia; oligospermia; and spermatogenic failure 21. Is an ortholog of human BRDT (bromodomain testis associated). WB:WBGene00010200 F57C7.4 Predicted to be located in membrane. WB:WBGene00010202 spig-6 Enriched in amphid sheath cell; muscle cell; and neurons based on RNA-seq and microarray studies. Is affected by several genes including skn-1; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; multi-walled carbon nanotube; and cholesterol based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00010203 F57E7.2 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including eat-2; nhr-49; and mec-8 based on tiling array; RNA-seq; and microarray studies. Is affected by Mercuric Chloride; Ag nanoparticles; and resveratrol based on microarray and RNA-seq studies. WB:WBGene00010204 cpr-9 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). WB:WBGene00010205 F57F5.3 Predicted to be located in membrane. WB:WBGene00010206 F57G4.1 Predicted to be located in membrane. WB:WBGene00010207 F57G4.2 No description available WB:WBGene00010208 F57G4.3 No description available WB:WBGene00010209 fbxa-191 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; rotenone; and metformin based on microarray and RNA-seq studies. WB:WBGene00010210 F57G4.5 No description available WB:WBGene00010211 F57G4.6 No description available WB:WBGene00010212 fbxa-192 Enriched in germ line; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including manganese chloride; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00010213 F57G4.9 No description available WB:WBGene00010214 slc-9B.2 Predicted to enable antiporter activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC9B1 (solute carrier family 9 member B1) and SLC9B2 (solute carrier family 9 member B2). WB:WBGene00010215 nhr-193 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00010216 F57G8.7 Enriched in several structures, including cephalic sheath cell; coelomocyte; dopaminergic neurons; mechanosensory neurons; and ventral nerve cord based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including Heme; Tunicamycin; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00010217 sre-31 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00010218 sre-30 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00010219 F57G9.3 Predicted to be located in membrane. WB:WBGene00010220 sre-29 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00010221 F57G12.1 Enriched in several structures, including ABalaaaarl; body wall musculature; intestine; neurons; and rectal muscle based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00010222 F57G12.2 Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00010223 F58A3.3 Enriched in RIBL and RIBR based on single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00010224 F58A3.4 Predicted to be located in cytoskeleton. WB:WBGene00010225 ttr-31 Predicted to be located in cell surface and extracellular region. WB:WBGene00010226 F58A4.1 Enriched in amphid sheath cell; male-specific anatomical entity; and in male based on RNA-seq and microarray studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00010227 F58A4.2 Enriched in I5 neuron; cholinergic neurons; germ line; germline precursor cell; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including manganese chloride; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00010228 clec-161 Predicted to enable signaling receptor activity. Predicted to be located in extracellular region. Expressed in germ line and vas deferens. Is an ortholog of human MRC1 (mannose receptor C-type 1). WB:WBGene00010229 F58A4.6 Enriched in several structures, including ABalapapap; ABalapppap; ABplpaaapp; ABprpaaapp; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; rotenone; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4807 and Domain of unknown function (DUF4807). WB:WBGene00010230 rpac-19 Predicted to enable protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase I and transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex and RNA polymerase III complex. Used to study obesity. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 2. Is an ortholog of human POLR1D (RNA polymerase I and III subunit D). WB:WBGene00010231 F58B3.4 Predicted to enable RNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Is an ortholog of human ESF1 (ESF1 nucleolar pre-rRNA processing protein homolog). WB:WBGene00010232 F58B3.6 Enriched in several structures, including AFD; VB neuron; dopaminergic neurons; germ line; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including hsf-1; lin-4; and lin-14 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Human IFRD2 enables ribosome binding activity and translation repressor activity. Is predicted to encode a protein with the following domains: Interferon-related protein conserved region; Interferon-related developmental regulator (IFRD); Interferon-related developmental regulator; Interferon-related developmental regulator, C-terminal; Armadillo-type fold; Interferon-related developmental regulator, N-terminal; and Phosphorylation site. Is an ortholog of human IFRD2 (interferon related developmental regulator 2). WB:WBGene00010233 rbm-17 Predicted to enable RNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part of spliceosomal complex. Is an ortholog of human RBM17 (RNA binding motif protein 17). WB:WBGene00010234 ttr-50 Predicted to be located in cell surface and extracellular region. WB:WBGene00010235 F58B4.2 Predicted to enable heme binding activity. Predicted to be located in intracellular membrane-bounded organelle and membrane. WB:WBGene00010236 F58B4.3 Expressed in ASEL; ASER; and neurons. WB:WBGene00010237 scvp-1 Enriched in male-specific anatomical entity based on microarray studies. Is affected by several genes including daf-2; eat-2; and hsp-6 based on RNA-seq and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Secreted clade V protein and Secreted clade V proteins. WB:WBGene00010238 F58B4.5 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00010239 F58B4.6 Enriched in coelomocyte; head mesodermal cell; intestine; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00010240 gadr-1 Expressed widely. WB:WBGene00010241 F58D2.2 Predicted to be located in membrane. WB:WBGene00010242 F58D5.2 Predicted to be located in membrane. WB:WBGene00010243 F58D5.3 Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00010244 F58D5.5 Enriched in NSM; OLL; PVD; neurons; and sensory neurons based on microarray and RNA-seq studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00010245 F58D5.6 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Tunicamycin; manganese chloride; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00010246 F58D5.7 Enriched in germ line; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00010247 F58D5.8 Predicted to be located in membrane. WB:WBGene00010248 F58D5.9 Enriched in AINL; AINR; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including hydrogen sulfide; antimycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00010249 F58D12.1 Predicted to be located in membrane. WB:WBGene00010250 F58D12.3 Enriched in AVK; germ line; and neurons based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and aak-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Tunicamycin; metformin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II. WB:WBGene00010251 sta-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to fungus; positive regulation of antifungal peptide production; and response to wounding. Located in several cellular components, including apical part of cell; endocytic vesicle; and hemidesmosome. Part of hemidesmosome associated protein complex. Expressed in hypodermis; interfacial epithelial cell; intestine; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including STAT1 (signal transducer and activator of transcription 1); STAT3 (signal transducer and activator of transcription 3); and STAT4 (signal transducer and activator of transcription 4). WB:WBGene00010253 F58E6.4 Predicted to be located in membrane. WB:WBGene00010254 F58E6.5 Predicted to enable FFAT motif binding activity. Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum-plasma membrane tethering. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. WB:WBGene00010255 F58E6.6 Predicted to be located in membrane. WB:WBGene00010256 hrg-3 Enables heme binding activity and heme transmembrane transporter activity. Involved in defense response to Gram-negative bacterium and heme transport. Located in extracellular space. Expressed in intestinal cell. WB:WBGene00010257 F58E6.8 Predicted to be located in membrane. WB:WBGene00010258 F58E6.11 Predicted to be located in membrane. Expressed in pharynx. WB:WBGene00010259 ric-7 Involved in several processes, including positive regulation of protein localization to presynapse; positive regulation of synapse pruning; and secretion by cell. Located in mitochondrion and synapse. Expressed in GABAergic neurons; cholinergic neurons; and head muscle. WB:WBGene00010260 ddx-17 Predicted to enable RNA binding activity and RNA helicase activity. Involved in pre-miRNA processing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ribonucleoprotein complex. Expressed in PVDL; PVDR; and neurons. Human ortholog(s) of this gene implicated in skin squamous cell carcinoma. Is an ortholog of human DDX17 (DEAD-box helicase 17). WB:WBGene00010261 srh-308 Predicted to be located in membrane. WB:WBGene00010262 droe-4 Enriched in excretory cell; muscle cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Neurotoxins; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5354 and Family of unknown function (DUF5354). WB:WBGene00010263 wago-4 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Involved in regulatory ncRNA-mediated heterochromatin formation. Acts upstream of or within with a positive effect on regulation of gene silencing by regulatory ncRNA. Predicted to be located in perinuclear region of cytoplasm. Expressed in several structures, including Psub3; Psub4; Z2; Z3; and oocyte. WB:WBGene00010264 F58G1.2 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Expressed in dorsal nerve cord; head muscle; and ventral nerve cord. WB:WBGene00010265 F58G1.3 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00010266 dct-18 Enriched in head mesodermal cell and pharyngeal muscle cell based on SAGE; tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by nineteen chemicals including methylmercury hydroxide; rotenone; and bisphenol A based on RNA-seq; proteomic; and microarray studies. WB:WBGene00010267 lips-9 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00010268 arrd-10 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. WB:WBGene00010269 F58G1.7 Predicted to be located in membrane. WB:WBGene00010270 F58G1.8 Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. WB:WBGene00010271 F58G1.9 Enriched in body wall muscle cell; germ line; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00010272 amph-1 Predicted to enable phospholipid binding activity. Involved in lipid tube assembly involved in organelle fission; nucleus localization; and nucleus organization. Located in nuclear envelope; perinuclear region of cytoplasm; and recycling endosome. Expressed in several structures, including coelomocyte; gonadal sheath cell; hypodermis; intestinal cell; and pharynx. Human ortholog(s) of this gene implicated in breast carcinoma; centronuclear myopathy 2; and prostate adenocarcinoma. Is an ortholog of human BIN1 (bridging integrator 1). WB:WBGene00010273 srm-3 Predicted to be located in membrane. Expressed in excretory cell; intestine; neurons; and pharynx. WB:WBGene00010274 F58G6.3 Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in copper ion transmembrane transport and intracellular copper ion homeostasis. Predicted to be located in late endosome membrane. WB:WBGene00010275 acc-1 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Predicted to be part of chloride channel complex. Expressed in ganglia and neurons. WB:WBGene00010276 C03A3.t1 No description available WB:WBGene00010277 F58G6.7 Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in copper ion transmembrane transport and intracellular copper ion homeostasis. Predicted to be located in late endosome membrane. WB:WBGene00010278 degl-2 Predicted to enable sodium channel activity. Predicted to be involved in sodium ion transport. Predicted to be located in membrane. WB:WBGene00010279 letm-1 Predicted to enable ribosome binding activity. Predicted to be located in mitochondrial inner membrane. Expressed widely. Is an ortholog of human LETM1 (leucine zipper and EF-hand containing transmembrane protein 1). WB:WBGene00010280 rde-12 Enables enzyme binding activity. Involved in response to exogenous dsRNA and siRNA processing. Located in P granule and perinuclear region of cytoplasm. Part of RNAi effector complex. Expressed in germ line and somatic cell. WB:WBGene00010281 mip-2 Expressed in P0; Psub1; Psub2; Psub3; and spermatocyte. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010282 F58G11.4 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00010283 ccz-1 Involved in lipid droplet disassembly and phagolysosome assembly involved in apoptotic cell clearance. Located in phagocytic vesicle. Used to study Hermansky-Pudlak syndrome. Is an ortholog of human CCZ1 (CCZ1 homolog, vacuolar protein trafficking and biogenesis associated) and CCZ1B (CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated). WB:WBGene00010284 aman-2 Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Located in Golgi apparatus. Expressed in head; pharynx; and ventral nerve cord. Is an ortholog of human MAN2A2 (mannosidase alpha class 2A member 2). WB:WBGene00010285 F58H1.2 Expressed in hypodermis. WB:WBGene00010286 F58H1.3 Predicted to enable acireductone synthase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human ENOPH1 (enolase-phosphatase 1). WB:WBGene00010288 F58H1.5 Predicted to be located in membrane. WB:WBGene00010289 F58H1.6 Predicted to be located in membrane. WB:WBGene00010290 F58H1.7 Expressed in glutamatergic neurons. Is predicted to encode a protein with the following domains: LDL receptor-like superfamily; Low-density lipoprotein receptor domain class A; and Low-density lipoprotein (LDL) receptor class A repeat. WB:WBGene00010291 F58H10.1 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; anterior hypodermis; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; Alovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00010292 F59A1.6 Enriched in body wall muscle cell; hypodermis; neurons; and in male based on tiling array and RNA-seq studies. Is affected by several genes including sir-2.1; pmk-1; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including Zidovudine; allantoin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00010293 fbxa-108 Enriched in several structures, including ABprpapppa; germ line; head mesodermal cell; neurons; and rect_D based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; glp-1; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including manganese chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00010294 fbxa-129 Enriched in DA neuron; VA neuron; germ line; germline precursor cell; and head mesodermal cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including stavudine; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00010295 fbxa-193 Enriched in several structures, including I5 neuron; cholinergic neurons; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq studies. WB:WBGene00010296 dgat-2 Predicted to enable diacylglycerol O-acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Located in lipid droplet. Is an ortholog of human MOGAT1 (monoacylglycerol O-acyltransferase 1). WB:WBGene00010297 F59A1.11 Predicted to be located in membrane. WB:WBGene00010298 F59A1.12 Predicted to be located in membrane. WB:WBGene00010299 F59A1.13 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00010300 F59A1.15 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00010301 F59A1.16 Enriched in male based on RNA-seq studies. Is affected by several genes including clk-1; tph-1; and cat-2 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00010303 cri-3 Predicted to be involved in cytosolic ribosome assembly. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 33. Is an ortholog of human C1QBP (complement C1q binding protein). WB:WBGene00010304 clpf-1 Enables ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity. Predicted to be involved in mRNA polyadenylation and tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 10. Is an ortholog of human CLP1 (cleavage factor polyribonucleotide kinase subunit 1). WB:WBGene00010305 F59A2.5 Predicted to be involved in tRNA threonylcarbamoyladenosine metabolic process. Predicted to be part of EKC/KEOPS complex. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 2. Is an ortholog of human LAGE3 (L antigen family member 3). WB:WBGene00010306 golg-4 Predicted to enable small GTPase binding activity. Predicted to be involved in Golgi vesicle transport. Predicted to be located in Golgi apparatus. Is an ortholog of human GOLGA4 (golgin A4). WB:WBGene00010307 skat-1 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in vacuolar membrane. Expressed in head neurons; intestine; tail neurons; ventral cord neurons; and vulval muscle. Human ortholog(s) of this gene implicated in iminoglycinuria. Is an ortholog of several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A4 (solute carrier family 36 member 4). WB:WBGene00010308 F59B2.3 Predicted to enable N-acetylglucosamine-6-phosphate deacetylase activity. Predicted to be involved in N-acetylglucosamine catabolic process. Is an ortholog of human AMDHD2 (amidohydrolase domain containing 2). WB:WBGene00010309 rpn-6.2 Predicted to enable structural molecule activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome regulatory particle, lid subcomplex. WB:WBGene00010310 F59B2.8 Enriched in several structures, including ABarpapaaa; DB neuron; accessory cell; interneuron; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00010311 F59B2.9 Enriched in germ line; intestine; motor neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including 1-methylnicotinamide; methylmercuric chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00010313 F59B2.11 Enriched in DA neuron and VA neuron based on tiling array studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including 1-methylnicotinamide; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00010314 F59B2.12 Expressed in coelomocyte; g1; head; and vas deferens. WB:WBGene00010315 F59B2.13 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in CANL; CANR; DVB; PVT; and body wall musculature. WB:WBGene00010316 F59B8.1 Enriched in excretory gland cell; neurons; retrovesicular ganglion; ventral nerve cord; and in male based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including aldicarb; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00010317 idh-1 Predicted to enable isocitrate dehydrogenase (NADP+) activity. Predicted to be involved in NADP metabolic process and isocitrate metabolic process. Predicted to be located in cytosol; mitochondrion; and peroxisome. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); glioblastoma; and hematologic cancer (multiple). Is an ortholog of human IDH1 (isocitrate dehydrogenase (NADP(+)) 1). WB:WBGene00010318 F59B10.2 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapapapa; head neurons; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; rrf-3; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00010319 F59B10.3 Predicted to be located in membrane. WB:WBGene00010320 F59B10.4 Predicted to be located in membrane. WB:WBGene00010321 F59B10.5 Enriched in several structures, including arc ant V; excretory system; hyp3; pharyngeal neurons; and socket cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including Heme; D-glucose; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00010322 F59B10.6 Predicted to be located in membrane. WB:WBGene00010323 dhhc-12 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Expressed in head neurons and tail neurons. WB:WBGene00010324 F59C6.3 Predicted to be located in membrane. WB:WBGene00010325 exos-3 Predicted to enable RNA binding activity. Predicted to be involved in RNA metabolic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1B and stomach cancer. Is an ortholog of human EXOSC3 (exosome component 3). WB:WBGene00010326 ndub-10 Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 35. Is an ortholog of human NDUFB10 (NADH:ubiquinone oxidoreductase subunit B10). WB:WBGene00010327 F59C6.8 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00010328 F59C6.11 Predicted to be located in membrane. WB:WBGene00010329 pcdr-1 Predicted to enable peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cellular response to hormone stimulus. Predicted to be located in membrane. Expressed in cholinergic neurons; ciliated neurons; rectal epithelium; ventral cord neurons; and vulval muscle. Is an ortholog of human GPR21 (G protein-coupled receptor 21) and GPR52 (G protein-coupled receptor 52). WB:WBGene00010330 F59D12.2 Predicted to be located in membrane. WB:WBGene00010331 F59D12.3 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00010332 F59D12.5 Enriched in germ line and intestine based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq; microarray; and tiling array studies. Is affected by eight chemicals including hydrogen sulfide; Doxycycline; and paraquat based on microarray and RNA-seq studies. WB:WBGene00010333 copz-1 Involved in embryo development; intracellular protein transport; and oocyte development. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be part of COPI vesicle coat. Is an ortholog of human COPZ1 (COPI coat complex subunit zeta 1) and COPZ2 (COPI coat complex subunit zeta 2). WB:WBGene00010334 del-5 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Expressed in intestinal cell. WB:WBGene00010335 F59F3.6 Predicted to be involved in protein homooligomerization. WB:WBGene00010336 acox-1.6 Predicted to enable acyl-CoA oxidase activity; fatty acid binding activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA oxidase and lipid homeostasis. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in peroxisomal acyl-CoA oxidase deficiency. Is an ortholog of human ACOX1 (acyl-CoA oxidase 1). WB:WBGene00010337 serp-1.1 Predicted to be involved in endoplasmic reticulum unfolded protein response. Predicted to be located in endoplasmic reticulum. Is an ortholog of human SERP1 (stress associated endoplasmic reticulum protein 1) and SERP2 (stress associated endoplasmic reticulum protein family member 2). WB:WBGene00010338 F59F4.3 Predicted to be located in membrane. WB:WBGene00010339 acl-1 Predicted to enable 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidic acid biosynthetic process. Predicted to be located in endoplasmic reticulum. Expressed in gonad. Is an ortholog of human AGPAT1 (1-acylglycerol-3-phosphate O-acyltransferase 1). WB:WBGene00010340 slcf-1 Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Located in basolateral plasma membrane. Expressed in intestine. WB:WBGene00010341 glo-3 Involved in gastrulation. Located in gut granule membrane. Expressed in intestine. WB:WBGene00010342 F59F5.3 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. WB:WBGene00010343 F59F5.4 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00010344 F59F5.5 Enriched in several structures, including ABalppppppa; ABplpaaaaa; ABpraaapppa; ABprpaaaaa; and neurons based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00010345 F59F5.7 Enriched in PLM; anterior hypodermis; interfacial epithelial cell; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: DM13 domain. WB:WBGene00010348 H01G02.1 Enriched in arcade cell; excretory cell; intestine; neurons; and pharyngeal cell based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00010349 dyf-18 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation and regulation of cell cycle. Predicted to be located in nucleus. Expressed in amphid neurons; head; inner labial neurons; outer labial neurons; and phasmid neurons. Is an ortholog of human CDK20 (cyclin dependent kinase 20). WB:WBGene00010350 H01G02.3 Predicted to be located in membrane. WB:WBGene00010351 cbd-1 Predicted to enable chitin binding activity. Involved in eggshell formation; positive regulation of protein localization to cell cortex; and positive regulation of protein localization to plasma membrane. Located in cell periphery. Expressed in germ line and oocyte. WB:WBGene00010352 fbxb-76 Enriched in several structures, including ABalppappa; ABarappppa; ABplppaapa; ABprppaapa; and touch receptor neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00010353 memi-3 Enriched in several structures, including ABalaapppa; ABalapaapa; germ line; germline precursor cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seventeen chemicals including rotenone; manganese chloride; and bisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010354 cyp-31A2 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Involved in several processes, including asymmetric cell division; embryonic morphogenesis; and female gamete generation. Used to study Bietti crystalline corneoretinal dystrophy. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Is an ortholog of human CYP4V2 (cytochrome P450 family 4 subfamily V member 2). WB:WBGene00010355 clec-229 Enriched in germline precursor cell; hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-7; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; tryptophan; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00010356 famk-1 Enables manganese ion binding activity and protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in Golgi apparatus. Expressed in gonad; oocyte; rectum; and vulva. Human ortholog(s) of this gene implicated in X-linked dominant hypophosphatemic rickets and amelogenesis imperfecta type 1G. Is an ortholog of human FAM20A (FAM20A golgi associated secretory pathway pseudokinase). WB:WBGene00010357 H03A11.2 Predicted to enable microtubule binding activity. Predicted to be located in microtubule cytoskeleton and sperm flagellum. Expressed in ASEL; ASER; and neurons. Is an ortholog of human SAXO1 (stabilizer of axonemal microtubules 1) and SAXO2 (stabilizer of axonemal microtubules 2). WB:WBGene00010358 H03G16.1 Enriched in FLP and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including eat-2; tdc-1; and set-2 based on tiling array and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00010359 mam-6 Enriched in arc ant V; hyp1; and hyp2 based on single-cell RNA-seq studies. Is affected by several genes including mex-3; fbf-1; and mex-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Sodium Chloride; copper sulfate; and Colistin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Concanavalin A-like lectin/glucanase domain superfamily. WB:WBGene00010360 fbxa-96 Enriched in head mesodermal cell; rect_D; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00010361 H03G16.5 Enriched in several structures, including ABalapaaaa; male distal tip cell; preanal ganglion neurons; rectum; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Tunicamycin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00010362 enu-3.1 Involved in axon extension involved in axon guidance. Located in neuronal cell body. Expressed in head; nervous system; and seam cell. WB:WBGene00010363 H04D03.2 Predicted to enable methylated histone binding activity. Predicted to be involved in chromosome attachment to the nuclear envelope and regulation of gene expression. Predicted to be located in nuclear inner membrane. WB:WBGene00010364 ecps-2 Predicted to be part of proteasome complex. Is an ortholog of human ECPAS (Ecm29 proteasome adaptor and scaffold). WB:WBGene00010365 H04D03.4 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00010366 H05L14.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00010367 H05L14.2 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Expressed in gonad. WB:WBGene00010368 H06A10.1 Involved in nematode larval development. WB:WBGene00010369 chd-1 Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and chromatin binding activity. Predicted to be involved in nucleosome organization and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed in several structures, including germ cell and somatic cell. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and developmental and epileptic encephalopathy 94. Is an ortholog of human CHD1 (chromodomain helicase DNA binding protein 1). WB:WBGene00010370 ctg-1 Involved in regulation of basement membrane organization. Predicted to be located in cytoplasm. Is an ortholog of several human genes including SEC14L2 (SEC14 like lipid binding 2); SEC14L3 (SEC14 like lipid binding 3); and SEC14L4 (SEC14 like lipid binding 4). WB:WBGene00010371 H06O01.4 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; rotenone; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00010372 H08J19.1 Enriched in neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; hpl-2; and spc-1 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube; adsorbable organic bromine compound; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00010373 H08M01.1 Predicted to enable metal ion binding activity. WB:WBGene00010374 rga-5 Predicted to enable GTPase activator activity. Predicted to be involved in Rho protein signal transduction; regulation of axonogenesis; and regulation of cell size. Predicted to be located in cytosol. Is an ortholog of human ARHGAP35 (Rho GTPase activating protein 35) and ARHGAP5 (Rho GTPase activating protein 5). WB:WBGene00010375 H09F14.1 Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection. WB:WBGene00010376 C05E7.t1 No description available WB:WBGene00010377 nspa-1 Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; methylmercuric chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00010378 H12D21.2 Enriched in AIN; arcade cell; germ line; neurons; and pharyngeal-intestinal valve cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00010379 H12D21.3 Is affected by several genes including hsf-1; eat-2; and pmk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00010380 mpst-2 Predicted to enable thiosulfate sulfurtransferase activity. Predicted to be located in mitochondrion. Is an ortholog of human MPST (mercaptopyruvate sulfurtransferase). WB:WBGene00010381 H12D21.5 Predicted to be located in membrane. WB:WBGene00010382 H12D21.6 Enriched in ABaraapapaa; ABaraapppaa; pharyngeal neurons; and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including elt-2; clk-1; and nhr-49 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; procyanidin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00010383 mpst-3 Predicted to enable thiosulfate sulfurtransferase activity. Predicted to be located in mitochondrion. Is an ortholog of human MPST (mercaptopyruvate sulfurtransferase). WB:WBGene00010384 H12D21.8 No description available WB:WBGene00010385 H12D21.9 Predicted to be located in membrane. WB:WBGene00010386 H12D21.10 Predicted to enable protein O-acetylglucosaminyltransferase activity. Predicted to be located in endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Is an ortholog of human EOGT (EGF domain specific O-linked N-acetylglucosamine transferase). WB:WBGene00010387 H12D21.11 Predicted to be located in membrane. WB:WBGene00010388 srz-42 Predicted to be located in membrane. WB:WBGene00010389 srz-31 Predicted to be located in membrane. WB:WBGene00010390 srz-30 Is affected by several genes including clk-1; ifg-1; and qui-1 based on microarray and RNA-seq studies. WB:WBGene00010391 oac-37 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00010392 oac-38 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00010393 H12I19.6 No description available WB:WBGene00010394 srz-59 Predicted to be located in membrane. WB:WBGene00010395 H12I19.8 Is affected by rsr-2 based on tiling array studies. WB:WBGene00010396 H13N06.2 Enriched in germline precursor cell; hypodermis; and rectal epithelial cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: von Willebrand factor A-like domain superfamily; von Willebrand factor, type A; and von Willebrand factor type A domain. WB:WBGene00010397 suox-1 Predicted to enable heme binding activity; molybdopterin cofactor binding activity; and sulfite oxidase activity. Predicted to be involved in sulfur compound metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in isolated sulfite oxidase deficiency. Is an ortholog of human SUOX (sulfite oxidase). WB:WBGene00010399 clec-13 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by Tunicamycin; Oligosaccharides; and Ethanol based on microarray studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00010400 clec-14 Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by Ethanol based on microarray studies. WB:WBGene00010401 H16D19.3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00010402 H16D19.4 Enriched in Z1.p; Z4.a; male distal tip cell; neurons; and somatic gonad precursor based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including rrf-3; sek-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride; multi-walled carbon nanotube; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00010403 otpl-8 Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1). WB:WBGene00010404 H19J13.2 Is affected by rsr-2; daf-2; and eat-2 based on tiling array and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5354 and Family of unknown function (DUF5354). WB:WBGene00010405 erfa-3 Predicted to enable GTPase activity and translation release factor activity. Predicted to be involved in translation. Predicted to be located in cytoplasm. Predicted to be part of translation release factor complex. Is an ortholog of human GSPT1 (G1 to S phase transition 1) and GSPT2 (G1 to S phase transition 2). WB:WBGene00010406 math-33 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and cysteine-type deubiquitinase activity. Involved in several processes, including anterior/posterior axis specification, embryo; hemidesmosome assembly; and maintenance of centrosome location. Located in cytoplasm and nucleus. Expressed in several structures, including germ cell and germ line. Is an ortholog of human USP7 (ubiquitin specific peptidase 7). WB:WBGene00010407 scb-1 Located in nucleus. Expressed in somatic cell. WB:WBGene00010408 mboa-2 Predicted to enable diacylglycerol O-acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in cardiomyopathy; congenital diarrhea 7 with exudative enteropathy; and obesity. Is an ortholog of human DGAT1 (diacylglycerol O-acyltransferase 1). WB:WBGene00010409 nse-4 Predicted to be involved in DNA repair. Predicted to be located in nucleus. Predicted to be part of Smc5-Smc6 complex. Is an ortholog of human EID3 (EP300 interacting inhibitor of differentiation 3) and NSMCE4A (NSE4 homolog A, SMC5-SMC6 complex component). WB:WBGene00010410 nhr-267 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00010411 H25K10.1 Predicted to enable acid phosphatase activity and metal ion binding activity. WB:WBGene00010412 H25K10.2 Enriched in body wall muscle cell based on tiling array studies. Is affected by daf-2; pmt-2; and sir-2.1 based on microarray studies. WB:WBGene00010413 H25K10.4 Enriched in hypodermis based on tiling array studies. Is affected by several genes including skn-1; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by eighteen chemicals including 4-bromodiphenyl ether; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4440; Domain of unknown function (DUF4440); and NTF2-like domain superfamily. WB:WBGene00010414 hpa-1 Predicted to be located in membrane. WB:WBGene00010415 irld-39 Enriched in neurons based on RNA-seq studies. Is affected by several genes including let-60; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00010416 hxk-2 Predicted to enable fructokinase activity and glucokinase activity. Predicted to be involved in carbohydrate metabolic process; glucose 6-phosphate metabolic process; and intracellular glucose homeostasis. Predicted to be located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 4G; hematologic cancer (multiple); and sickle cell anemia. Is an ortholog of several human genes including HK1 (hexokinase 1); HK2 (hexokinase 2); and HK3 (hexokinase 3). WB:WBGene00010417 clpr-3 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00010418 H27A22.1 Predicted to enable glutaminyl-peptide cyclotransferase activity and zinc ion binding activity. Expressed in head and tail. Is an ortholog of human QPCT (glutaminyl-peptide cyclotransferase). WB:WBGene00010419 atp-1 Enables enterobactin binding activity. Involved in iron import into cell. Located in mitochondrion. Expressed in tail. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 22 and vascular dementia. Is an ortholog of human ATP5F1A (ATP synthase F1 subunit alpha). WB:WBGene00010420 mcrs-1 Predicted to enable G-quadruplex RNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of NSL complex. Is an ortholog of human MCRS1 (microspherule protein 1). WB:WBGene00010421 slc-36.4 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in L-amino acid transport and amino acid transmembrane transport. Predicted to be located in vacuolar membrane. Human ortholog(s) of this gene implicated in iminoglycinuria. Is an ortholog of several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A4 (solute carrier family 36 member 4). WB:WBGene00010422 H32K16.2 Enriched in body wall muscle cell; hypodermis; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by eighteen chemicals including methylmercuric chloride; rotenone; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00010423 zmp-5 Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to be located in extracellular space. Expressed in dorsal uterine cell. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and carcinoma (multiple). Is an ortholog of human MMP16 (matrix metallopeptidase 16). WB:WBGene00010424 lep-5 Expressed in several structures, including nervous system; pharynx; seam cell; somatic gonad; and vulva. WB:WBGene00010425 lpin-1 Predicted to enable phosphatidate phosphatase activity and transcription coactivator activity. Involved in several processes, including endomembrane system organization; macromolecule localization; and mitotic sister chromatid segregation. Located in endoplasmic reticulum; nuclear envelope; and nucleoplasm. Expressed in head neurons and hypodermis. Used to study obesity. Human ortholog(s) of this gene implicated in morbid obesity. Is an ortholog of human LPIN2 (lipin 2). WB:WBGene00010426 H37A05.2 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00010427 hpo-11 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and endomembrane system. Is an ortholog of human NRBP1 (nuclear receptor binding protein 1) and NRBP2 (nuclear receptor binding protein 2). WB:WBGene00010428 dcn-1 Enables ubiquitin binding activity. Involved in microtubule cytoskeleton organization and protein metabolic process. Located in cytoplasm and nucleus. Is an ortholog of human DCUN1D1 (defective in cullin neddylation 1 domain containing 1) and DCUN1D2 (defective in cullin neddylation 1 domain containing 2). WB:WBGene00010430 C05E7.t2 No description available WB:WBGene00010431 C05E7.t3 No description available WB:WBGene00010432 H39E23.2 Enriched in ABplapaaap; ABprapaaap; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; npr-1; and mex-3 based on RNA-seq and microarray studies. Is affected by eight chemicals including Tunicamycin; stavudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00010433 H40L08.1 Predicted to enable ubiquitin binding activity. Is an ortholog of human FAF2 (Fas associated factor family member 2). WB:WBGene00010434 H40L08.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Is an ortholog of human CFAP57 (cilia and flagella associated protein 57). WB:WBGene00010435 pwp-1 Predicted to be involved in rRNA processing. Predicted to be located in nucleus. Is an ortholog of human PWP1 (PWP1 homolog, endonuclein). WB:WBGene00010436 JC8.4 Predicted to enable tRNA-specific adenosine-34 deaminase activity. Predicted to be involved in tRNA wobble adenosine to inosine editing. Is an ortholog of human ADAT2 (adenosine deaminase tRNA specific 2). WB:WBGene00010437 cox-11 Predicted to enable copper ion binding activity. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX11 (cytochrome c oxidase copper chaperone COX11). WB:WBGene00010439 JC8.7 Predicted to enable histone binding activity and poly-ADP-D-ribose binding activity. Predicted to be involved in DNA damage response. Predicted to be located in nucleus. Is an ortholog of human HPF1 (histone PARylation factor 1). WB:WBGene00010440 ttr-51 Predicted to be located in cell surface and extracellular region. Expressed in spermatheca. WB:WBGene00010442 bus-12 Predicted to enable antiporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in Golgi apparatus. Expressed in intestine and seam cell. Is an ortholog of human SLC35D3 (solute carrier family 35 member D3). WB:WBGene00010444 magi-1 Enables beta-catenin binding activity and glutamate receptor binding activity. Involved in habituation; long-term memory; and regulation of protein localization. Located in adherens junction and synapse. Expressed in several structures, including anus; egg-laying apparatus; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in nephrotic syndrome type 15. Is an ortholog of human MAGI3 (membrane associated guanylate kinase, WW and PDZ domain containing 3). WB:WBGene00010446 K01A6.4 Enriched in interfacial epithelial cell and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; elt-2; and sek-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including aldicarb; Mercuric Chloride; and bisphenol A based on microarray and RNA-seq studies. WB:WBGene00010447 K01A6.5 Enriched in several structures, including ABalppappa; ABalpppapa; ABalpppppa; amphid neurons; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and hsp-6 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Rifampin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00010448 K01A6.6 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00010449 K01A11.1 Enriched in several structures, including ABplapapppp; ABprapapppp; enteric muscle; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; multi-walled carbon nanotube; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00010450 metl-18 Predicted to enable protein-L-histidine N-tele-methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human METTL18 (methyltransferase 18, RPL3 N3(tau)-histidine). WB:WBGene00010451 K01A11.3 Is affected by several genes including skn-1; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; multi-walled carbon nanotube; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00010452 K01A11.5 No description available WB:WBGene00010453 fozi-1 Predicted to enable actin filament binding activity. Involved in mesodermal cell fate specification and positive regulation of mesodermal cell fate specification. Located in nucleus. Expressed in several structures, including M.dla; amphid neurons; body wall muscle cell from M lineage; coelomocyte; and somatic nervous system. Is an ortholog of human FMNL1 (formin like 1). WB:WBGene00010454 K01B6.3 Enriched in germline precursor cell; hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eighteen chemicals including rotenone; multi-walled carbon nanotube; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010455 K01B6.4 Enriched in OLQ; anterior ganglion (post); and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; mex-3; and mex-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00010456 srdh-1 Predicted to enable L-serine ammonia-lyase activity and L-threonine ammonia-lyase activity. Predicted to be involved in L-serine catabolic process; isoleucine biosynthetic process; and threonine catabolic process. WB:WBGene00010457 K01C8.2 Enriched in several structures, including AVE; arcade cell; excretory gland cell; nerve ring neurons; and pharynx based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and pmk-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Lustrin, cysteine-rich repeated domain; Lustrin, cysteine-rich repeated; and Cysteine-rich repeat. WB:WBGene00010458 mrpl-10 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL10 (mitochondrial ribosomal protein L10). WB:WBGene00010459 slc-25A32 Predicted to enable FAD transmembrane transporter activity and folic acid transmembrane transporter activity. Predicted to be involved in folate import into mitochondrion. Predicted to be located in mitochondrion. Is an ortholog of human SLC25A32 (solute carrier family 25 member 32). WB:WBGene00010460 clec-142 Enriched in AFD; germ line; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; mianserin; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00010461 K01D12.1 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00010462 K01D12.2 No description available WB:WBGene00010463 K01D12.3 Enriched in male-specific anatomical entity based on microarray studies. Is affected by several genes including sir-2.1; clk-1; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00010464 K01D12.5 Enriched in AVEL and AVER based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; 1-methylnicotinamide; and rotenone based on microarray and RNA-seq studies. WB:WBGene00010465 miga-1 Predicted to be involved in mitochondrial fusion. Predicted to be located in membrane and mitochondrion. Is an ortholog of human MIGA1 (mitoguardin 1) and MIGA2 (mitoguardin 2). WB:WBGene00010466 K01D12.7 Predicted to enable DNA binding activity. WB:WBGene00010467 K01D12.8 Enriched in AFD; dopaminergic neurons; germline precursor cell; hypodermis; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; D-glucose; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00010468 K01D12.9 Enriched in AFD; ASER; germline precursor cell; hypodermis; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-nine chemicals including Heme; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00010469 K01D12.10 Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including methylmercuric chloride; sucrose; and stearic acid based on microarray and RNA-seq studies. WB:WBGene00010470 cdr-4 Involved in stress response to cadmium ion. Acts upstream of or within IRE1-mediated unfolded protein response. Located in lysosome. Expressed in pm5; pm6; and pm7. WB:WBGene00010471 cdr-6 Predicted to be located in cytoplasm. WB:WBGene00010472 cdr-7 Predicted to be located in cytoplasm. WB:WBGene00010473 hrg-2 Enables heme binding activity. Predicted to be located in cytoplasm. Expressed in hypodermis. WB:WBGene00010474 K01D12.15 Enriched in arcade cell; germ line; pharyngeal-intestinal valve cell; preanal ganglion neurons; and sperm based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00010475 K01F9.2 Enriched in several structures, including ABalapapapa; ABalapppapa; ABarpapaapp; head mesodermal cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including 1-methylnicotinamide; Tunicamycin; and 4-bromodiphenyl ether based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010476 rnf-113 Enables ubiquitin-protein transferase activity. Involved in protein ubiquitination. Located in nucleus. Expressed in head neurons; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 5. Is an ortholog of human RNF113A (ring finger protein 113A). WB:WBGene00010477 enu-3.6 Predicted to be involved in axon extension involved in axon guidance. Predicted to be located in neuronal cell body. WB:WBGene00010478 dkc-1 Predicted to enable pseudouridine synthase activity. Predicted to be involved in box H/ACA RNA 3'-end processing and pseudouridine synthesis. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex. Human ortholog(s) of this gene implicated in X-linked dyskeratosis congenita and aplastic anemia. Is an ortholog of human DKC1 (dyskerin pseudouridine synthase 1). WB:WBGene00010479 K01G5.8 Located in nucleolus. Is an ortholog of human FAM32A (family with sequence similarity 32 member A). WB:WBGene00010480 tasp-1 Predicted to enable asparaginase activity; beta-aspartyl-peptidase activity; and threonine-type endopeptidase activity. Predicted to be involved in protein maturation. Predicted to be located in cytoplasm. Is an ortholog of human TASP1 (taspase 1). WB:WBGene00010481 K01G5.10 Predicted to enable hydrolase activity. Predicted to be located in nucleus. Is an ortholog of human HDHD3 (haloacid dehalogenase like hydrolase domain containing 3). WB:WBGene00010483 K01G12.3 Enriched in AB; germ line; and pharyngeal muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including mianserin; D-glucose; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00010484 dph-3 Predicted to enable ferrous iron binding activity and iron chaperone activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine and tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation. Located in nucleus. Is an ortholog of human DPH3 (diphthamide biosynthesis 3) and DPH3P1 (diphthamide biosynthesis 3 pseudogene 1). WB:WBGene00010485 ant-1.3 Predicted to enable adenine nucleotide transmembrane transporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Expressed in VA11 and intestine. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A5 (solute carrier family 25 member 5) and SLC25A6 (solute carrier family 25 member 6). WB:WBGene00010486 K01H12.4 Enriched in AVL; germ line; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-four chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00010487 K02A11.2 Enriched in ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABprpaaapa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by four chemicals including cholesterol; paraquat; and Diazinon based on RNA-seq and microarray studies. WB:WBGene00010488 endu-1 Predicted to enable RNA binding activity and RNA endonuclease activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. Predicted to be located in extracellular region. Is an ortholog of human ENDOU (endonuclease, poly(U) specific). WB:WBGene00010489 K02B7.1 No description available WB:WBGene00010490 K02B7.2 No description available WB:WBGene00010491 K02B7.3 Enriched in several structures, including excretory cell; germ line; muscle cell; neurons; and rectal epithelial cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00010492 meg-1 Involved in P granule disassembly and germ cell proliferation. Located in P granule. Expressed in Psub2; Psub3; Psub4; and germ line. WB:WBGene00010493 meg-2 Involved in P granule disassembly. Located in P granule. Expressed in germ line. WB:WBGene00010494 K02B9.3 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; alg-1; and etr-1 based on tiling array and RNA-seq studies. Is affected by cadmium and allantoin based on microarray studies. WB:WBGene00010495 K02B12.2 Enriched in several structures, including ABalaapppa; ABalaappppa; ABalapaapa; ciliated neurons; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including rotenone; bisphenol A; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00010496 sec-12 Predicted to enable GTPase activator activity. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. Is an ortholog of human PREB (prolactin regulatory element binding). WB:WBGene00010497 axl-1 Enables protein kinase binding activity. Involved in axon guidance and negative regulation of Wnt signaling pathway. WB:WBGene00010498 tnsl-1 Enriched in several structures, including Z1.p; body wall muscle cell; germ line; germline precursor cell; and male distal tip cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including aldicarb; rotenone; and D-glucose based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Sponastrime type. Human TONSL enables histone binding activity and histone reader activity. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily; Phosphorylation site; Ankyrin repeats (3 copies); Putative ankyrin repeat domain-containing protein 31; Tetratricopeptide-like helical domain superfamily; Ankyrin repeat-containing domain superfamily; Ankyrin repeat; and Ankyrin repeats (many copies). Is an ortholog of human TONSL (tonsoku like, DNA repair protein). WB:WBGene00010499 K02B12.6 Enriched in ABalpapaap; ABarappaap; excretory duct; excretory pore; and male-specific anatomical entity based on single-cell RNA-seq and microarray studies. Is affected by several genes including rrf-3; let-7; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including tryptophan; mianserin; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00010500 K02B12.7 Predicted to enable GTPase activator activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in Golgi membrane. Is an ortholog of human ARFGAP1 (ADP ribosylation factor GTPase activating protein 1). WB:WBGene00010501 K02C4.2 Enriched in OLL; PVD; dopaminergic neurons; and somatic gonad precursor based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00010502 K02C4.3 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of protein stability. Predicted to be located in cytosol and nucleus. Is an ortholog of human USP25 (ubiquitin specific peptidase 25) and USP28 (ubiquitin specific peptidase 28). WB:WBGene00010503 K02C4.5 Enriched in hypodermis; intestine; sensory neurons; and somatic gonad precursor based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010504 K02D3.1 Enriched in several structures, including GLR; body wall muscle cell from MS lineage; head mesodermal cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including rotenone; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Uncharacterized protein F10E9.3-like. WB:WBGene00010505 K02D3.2 Predicted to enable lipid binding activity. Is an ortholog of human STARD4 (StAR related lipid transfer domain containing 4). WB:WBGene00010506 K02E2.1 Predicted to be located in membrane. WB:WBGene00010507 K02E2.6 Enriched in several structures, including MSpppaaa; head mesodermal cell; intestine; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; hsf-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Aspartic peptidase domain superfamily and gag-polyprotein putative aspartyl protease. WB:WBGene00010508 K02E2.7 Predicted to be located in motile cilium. WB:WBGene00010509 K02E2.8 Enriched in several structures, including I5 neuron; cholinergic neurons; germline precursor cell; muscle cell; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including tryptophan; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00010510 ent-3 Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Is an ortholog of human SLC29A2 (solute carrier family 29 member 2) and SLC29A3 (solute carrier family 29 member 3). WB:WBGene00010511 sre-7 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00010512 K02E11.3 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; multi-walled carbon nanotube; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00010513 K02E11.4 Expressed in amphid sheath cell. WB:WBGene00010514 K02E11.5 Enriched in AFD; interfacial epithelial cell; pharyngeal-intestinal valve cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; bisphenol A; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00010515 K02E11.6 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; RNA-seq; and tiling array studies. Is affected by seventeen chemicals including rotenone; multi-walled carbon nanotube; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00010516 K02E11.7 Enriched in PLM; amphid sheath cell; and hypodermis based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; methylmercuric chloride; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00010517 K02E11.8 Is affected by clk-1 and daf-16 based on microarray and RNA-seq studies. WB:WBGene00010518 K02E11.9 Enriched in amphid sheath cell; arcade cell; and pharyngeal-intestinal valve cell based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies. WB:WBGene00010519 K03A11.1 Predicted to enable DNA binding activity. WB:WBGene00010520 cpx-2 Predicted to enable syntaxin binding activity. Predicted to be involved in exocytosis and neurotransmitter transport. Predicted to be located in cellular anatomical entity. Expressed in head neurons and tail neurons. WB:WBGene00010521 K03A11.4 Predicted to be located in membrane. WB:WBGene00010522 K03A11.5 Predicted to be located in membrane. WB:WBGene00010523 K03B8.4 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by cadmium and Sirolimus based on microarray studies. WB:WBGene00010524 K03B8.6 Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and carcinoma (multiple). Is an ortholog of human MMP2 (matrix metallopeptidase 2); MMP23B (matrix metallopeptidase 23B); and MMP9 (matrix metallopeptidase 9). WB:WBGene00010525 K03B8.8 Expressed in Z1 and Z4. WB:WBGene00010526 K03B8.11 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; pie-1; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Mercuric Chloride; and stavudine based on microarray and RNA-seq studies. WB:WBGene00010527 srz-74 Predicted to be located in membrane. WB:WBGene00010528 K03D3.2 Enriched in several structures, including cephalic sheath cell; coelomocyte; neurons; somatic gonad precursor; and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including methylmercury hydroxide; mianserin; and iron oxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00010529 srz-21 Is affected by several genes including let-60; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Chlorpyrifos and adsorbable organic bromine compound based on microarray studies. WB:WBGene00010530 srz-61 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00010531 K03D3.5 Enriched in male based on RNA-seq studies. Is affected by several genes including age-1; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Alovudine; stavudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00010532 K03D3.6 No description available WB:WBGene00010533 K03D3.8 No description available WB:WBGene00010534 fbxa-102 Is affected by several genes including hpl-2; drh-3; and sin-3 based on tiling array and RNA-seq studies. Is affected by multi-walled carbon nanotube and resveratrol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00010535 K03D7.8 Enriched in NSM based on tiling array studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by five chemicals including Rifampin; allantoin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00010536 K03D7.9 Is affected by hpl-2 and rsr-2 based on tiling array studies. WB:WBGene00010537 mys-2 Predicted to enable histone H4K16 acetyltransferase activity and transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of MSL complex. Expressed in germ line. Human ortholog(s) of this gene implicated in breast cancer and clear cell renal cell carcinoma. Is an ortholog of human KAT8 (lysine acetyltransferase 8). WB:WBGene00010538 ttr-3 Predicted to be located in cell surface and extracellular region. Expressed in seam cell and ventral cord blast cell. WB:WBGene00010539 ttr-2 Predicted to be located in cell surface and extracellular region. WB:WBGene00010540 K03H1.5 Predicted to be involved in cell-matrix adhesion. Predicted to be located in extracellular space. Is an ortholog of human SUSD2 (sushi domain containing 2). WB:WBGene00010541 ttr-1 Predicted to be located in cell surface and extracellular region. WB:WBGene00010542 K03H1.7 Enriched in several structures, including ABalapaaaa; ciliated neurons; germ line; male distal tip cell; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00010543 K03H1.8 Is affected by several genes including daf-2; eat-2; and dcr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; Tunicamycin; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00010544 K03H1.9 Predicted to be located in membrane. WB:WBGene00010545 cbp-2 Predicted to enable histone acetyltransferase activity; metal ion binding activity; and transcription coregulator activity. Predicted to be involved in DNA-templated transcription; chromatin remodeling; and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00010546 K03H1.11 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABplaapaap; NSM; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including rotenone; Zidovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00010547 K03H1.12 Predicted to be located in membrane. WB:WBGene00010550 K04B12.2 Enriched in several structures, including ABalppppaa; ABalppppppa; ABplaapaap; amphid sheath cell; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sek-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00010551 smg-8 Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Located in striated muscle dense body. Is an ortholog of human SMG8 (SMG8 nonsense mediated mRNA decay factor). WB:WBGene00010552 K04C1.2 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABplpaaaap; PVR; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Zidovudine; paraquat; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Sterile alpha motif/pointed domain superfamily. WB:WBGene00010553 K04C1.3 Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. WB:WBGene00010554 mlc-6 Predicted to enable calcium ion binding activity. Predicted to be part of myosin II complex. Human ortholog(s) of this gene implicated in cardiomyopathy and familial atrial fibrillation. Is an ortholog of human MYL4 (myosin light chain 4); MYL6 (myosin light chain 6); and MYL6B (myosin light chain 6B). WB:WBGene00010555 K04C1.5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00010556 rack-1 Predicted to enable protein kinase C binding activity and ribosome binding activity. Involved in several processes, including antifungal innate immune response; cytoskeleton-dependent cytokinesis; and motor neuron axon guidance. Located in several cellular components, including centrosome; growth cone; and kinetochore. Expressed in anterior distal tip cell; neurons; and posterior distal tip cell. Is an ortholog of human RACK1 (receptor for activated C kinase 1). WB:WBGene00010557 mspn-1 Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in extraction of mislocalized protein from mitochondrial outer membrane. Predicted to be located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in hyperekplexia 4. Is an ortholog of human ATAD1 (ATPase family AAA domain containing 1). WB:WBGene00010558 ptrg-1 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00010559 K04D7.6 Predicted to be located in membrane. WB:WBGene00010560 eif-2beta Predicted to enable mRNA binding activity; translation initiation factor activity; and translation initiation factor binding activity. Involved in determination of adult lifespan; regulation of growth; and translation. Predicted to be part of eukaryotic translation initiation factor 2 complex. Is an ortholog of human EIF2S2 (eukaryotic translation initiation factor 2 subunit beta). WB:WBGene00010562 cdc-48.3 Enables ATP hydrolysis activity; protein kinase binding activity; and protein kinase inhibitor activity. Predicted to be involved in cell division. Located in cytoplasm. Is an ortholog of human AFG2A (AFG2 AAA ATPase homolog A). WB:WBGene00010563 K04G2.4 Enriched in germ line; intestine; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including Ethanol; methylmercuric chloride; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00010564 ath-1 Predicted to enable carboxylic ester hydrolase activity and palmitoyl-(protein) hydrolase activity. Predicted to be located in cytoplasm. Is an ortholog of human LYPLA1 (lysophospholipase 1). WB:WBGene00010565 vacl-14 Predicted to be involved in phosphatidylinositol biosynthetic process. Predicted to be located in endosome membrane. Predicted to be part of PAS complex. Human ortholog(s) of this gene implicated in striatonigral degeneration. Is an ortholog of human VAC14 (VAC14 component of PIKFYVE complex). WB:WBGene00010566 K04G2.7 Enriched in AFD; MSpaaapa; mechanosensory neurons; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by nine chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: HTH CenpB-type DNA-binding domain; Homeobox-like domain superfamily; and Tc5 transposase DNA-binding domain. WB:WBGene00010567 K04G2.9 Located in plasma membrane. WB:WBGene00010568 K04G2.10 Enriched in several structures, including ABplaapapa; ABplpapapa; BAG; amphid neurons; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including methylmercury hydroxide; rotenone; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00010569 scbp-2 Predicted to be located in ribosome. WB:WBGene00010570 K04G11.1 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-2; daf-12; and csr-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00010571 K04G11.3 Enriched in intestine and rectal gland cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; hsf-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including stavudine; Zidovudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: RSD-2, N-terminal and RSD-2 N-terminal domain. WB:WBGene00010572 wdr-5.2 Predicted to enable dynein complex binding activity and microtubule plus-end binding activity. Predicted to be involved in several processes, including brain morphogenesis; microtubule-based process; and nuclear migration. Predicted to be located in several cellular components, including neuronal cell body; nuclear envelope; and supramolecular complex. Predicted to be part of microtubule associated complex. WB:WBGene00010573 chtb-1 Predicted to enable chitin binding activity. Predicted to be located in extracellular region. WB:WBGene00010574 K04H4.5 Enriched in several structures, including GABAergic neurons; GLR; germ line; somatic gonad precursor; and sperm based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00010575 flp-25 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in ASEL; ASER; and neurons. WB:WBGene00010576 clec-116 Predicted to be located in membrane. WB:WBGene00010577 K04H8.2 Is affected by rsr-2; clk-1; and lsm-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Atrazine and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; C-type lectin fold; and PAN-3 domain. WB:WBGene00010578 K04H8.3 Enriched in ABprpapppa; male-specific anatomical entity; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies. WB:WBGene00010579 K05C4.2 Predicted to be involved in endoplasmic reticulum organization and vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in severe congenital neutropenia 6. Is an ortholog of human JAGN1 (jagunal homolog 1). WB:WBGene00010580 K05C4.3 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00010581 K05C4.4 Enriched in ABplppppaa; ABprppppaa; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and elt-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; antimycin; and Ag nanoparticles based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00010582 K05C4.5 Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of 90S preribosome; small-subunit processome; and t-UTP complex. Human ortholog(s) of this gene implicated in cholestasis and primary biliary cholangitis. Is an ortholog of human UTP4 (UTP4 small subunit processome component). WB:WBGene00010583 K05C4.7 Predicted to be located in mitochondrial outer membrane. Is an ortholog of human ARMC1 (armadillo repeat containing 1). WB:WBGene00010584 K05C4.8 Enriched in cholinergic neurons; coelomocyte; interneuron; and retrovesicular ganglion based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00010585 K05C4.9 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00010586 K05C4.10 Predicted to be located in membrane. WB:WBGene00010587 sol-2 Enables channel regulator activity. Involved in several processes, including hyperosmotic response; positive regulation of glutamatergic synaptic transmission; and thigmotaxis. Located in neuron projection membrane. Part of ionotropic glutamate receptor complex. Expressed in command interneuron; head neurons; and tail neurons. WB:WBGene00010588 srz-14 Predicted to be located in membrane. WB:WBGene00010589 cyp-33D1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Keshan disease; glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C19 (cytochrome P450 family 2 subfamily C member 19); and CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00010590 srz-13 Predicted to be located in membrane. WB:WBGene00010591 K05D4.9 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00010592 K06A4.2 Predicted to be located in membrane. WB:WBGene00010593 gsnl-1 Enables actin filament binding activity; actin monomer binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in actin filament-based process and regulation of cellular component organization. Located in actin cytoskeleton and striated muscle dense body. Expressed in hypodermis. Human ortholog(s) of this gene implicated in several diseases, including Finnish type amyloidosis; artery disease (multiple); and gas gangrene. Is an ortholog of human CAPG (capping actin protein, gelsolin like). WB:WBGene00010594 swt-5 Predicted to enable sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport. Predicted to be located in Golgi membrane and plasma membrane. WB:WBGene00010595 haao-1 Predicted to enable 3-hydroxyanthranilate 3,4-dioxygenase activity. Predicted to be involved in 'de novo' NAD biosynthetic process from tryptophan and quinolinate metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human HAAO (3-hydroxyanthranilate 3,4-dioxygenase). WB:WBGene00010596 K06A4.6 Enriched in URXL; URXR; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00010597 K06A4.7 Enriched in arcade cell; intestine; and marginal cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00010598 K06B4.3 Is affected by several genes including sir-2.1; clk-1; and mir-34 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00010599 K06B4.4 Predicted to be located in membrane. WB:WBGene00010600 nhr-196 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons. WB:WBGene00010601 nhr-268 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00010602 nhr-197 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00010603 nhr-198 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00010604 nhr-199 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00010605 K06G5.1 Enriched in AFD; head mesodermal cell; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-one chemicals including mianserin; D-glucopyranose; and D-glucose based on RNA-seq; microarray; and proteomic studies. WB:WBGene00010606 cyp-13B2 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00010607 K06G5.3 Predicted to enable DNA binding activity. WB:WBGene00010608 K07A1.1 Predicted to be located in membrane. WB:WBGene00010609 dut-1 Predicted to enable dUTP diphosphatase activity and magnesium ion binding activity. Predicted to be involved in dUMP biosynthetic process and dUTP catabolic process. Expressed in intestine. Is an ortholog of human DUT (deoxyuridine triphosphatase). WB:WBGene00010610 K07A1.3 Predicted to enable ATP binding activity and aminopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Is an ortholog of human ACTMAP (actin maturation protease). WB:WBGene00010611 K07A1.4 Enriched in germ line; intestine; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00010612 K07A1.5 Predicted to be located in membrane. WB:WBGene00010613 K07A1.6 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00010614 cri-1 Expressed in amphid neurons; intestine; marginal cell; and rectal gland cell. Is predicted to encode a protein with the following domains: Headcase protein and Headcase, middle domain. Is an ortholog of human HECA (hdc homolog, cell cycle regulator). WB:WBGene00010615 ate-1 Predicted to enable arginyl-tRNA--protein transferase activity. Predicted to be located in cytoplasm. Is an ortholog of human ATE1 (arginyltransferase 1). WB:WBGene00010616 K07A1.10 Predicted to be located in mitochondrion. Is an ortholog of human GADD45GIP1 (GADD45G interacting protein 1). WB:WBGene00010617 K07A1.13 Predicted to be located in membrane. WB:WBGene00010618 K07A1.14 Is affected by daf-2 and eat-2 based on microarray studies. Is affected by methylmercuric chloride and Colistin based on microarray studies. WB:WBGene00010619 K07A1.15 Predicted to enable U7 snRNA binding activity and histone pre-mRNA DCP binding activity. Predicted to be involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Predicted to be located in nuclear body. Predicted to be part of cytoplasmic U snRNP body. Is an ortholog of human LSM10 (LSM10, U7 small nuclear RNA associated). WB:WBGene00010620 K07A12.1 Predicted to be part of RQC complex. Is an ortholog of human TCF25 (transcription factor 25). WB:WBGene00010621 egg-6 Predicted to be located in apical plasma membrane. Expressed in excretory system; neurons; pharynx; rectal epithelial cell; and vulva. WB:WBGene00010622 hbs-1 Predicted to enable GTPase activity. Predicted to be involved in translation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in beta thalassemia. Is an ortholog of human HBS1L (HBS1 like translational GTPase). WB:WBGene00010623 K07A12.5 Enriched in AVA; germ line; intestine; muscle cell; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00010624 mrps-15 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS15 (mitochondrial ribosomal protein S15). WB:WBGene00010625 K07C5.2 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. WB:WBGene00010626 K07C5.3 Predicted to enable DNA ligase (ATP) activity. Predicted to be involved in DNA ligation and lagging strand elongation. Predicted to be located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 20 and pancreatic cancer. Is an ortholog of human LIG3 (DNA ligase 3). WB:WBGene00010627 nol-56 Predicted to enable snoRNA binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in nucleolus. Predicted to be part of box C/D RNP complex and small-subunit processome. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 36. Is an ortholog of human NOP56 (NOP56 ribonucleoprotein). WB:WBGene00010628 ceeh-2 Enables epoxide hydrolase activity. Involved in cellular lipid metabolic process. Is an ortholog of human EPHX3 (epoxide hydrolase 3) and EPHX4 (epoxide hydrolase 4). WB:WBGene00010629 sluh-7 Predicted to enable enzyme binding activity; pre-mRNA 3'-splice site binding activity; and zinc ion binding activity. Predicted to be involved in RNA splicing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human SLU7 (SLU7 homolog, splicing factor). WB:WBGene00010630 ttll-15 Predicted to enable ATP binding activity and ligase activity. Involved in egg-laying behavior. WB:WBGene00010631 cash-1 Predicted to enable calmodulin binding activity. Involved in epithelial tube morphogenesis; positive regulation of endocytic recycling; and regulation of Golgi organization. Predicted to be located in membrane and protein-containing complex. Is an ortholog of human STRN3 (striatin 3). WB:WBGene00010632 K07C5.9 Expressed in intestine and nervous system. WB:WBGene00010633 nspd-2 Enriched in amphid sheath cell; germline precursor cell; intestine; sperm; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-eight chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Caenorhabditis elegans protein of unknown function (DUF780) and Protein of unknown function DUF780, Caenorhabditis species. WB:WBGene00010634 K07F5.6 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00010635 K07F5.7 Predicted to be located in cytoskeleton. WB:WBGene00010636 K07F5.8 Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of human PTPN7 (protein tyrosine phosphatase non-receptor type 7). WB:WBGene00010637 K07F5.12 Predicted to enable carbohydrate transmembrane transporter activity. Predicted to be involved in carbohydrate transmembrane transport. Predicted to be located in membrane. Is an ortholog of human TMEM144 (transmembrane protein 144). WB:WBGene00010638 K07F5.14 Enriched in body wall muscle cell; germ line; intestine; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including manganese chloride; D-glucose; and Rifampin based on RNA-seq and microarray studies. Human NOL8 enables RNA binding activity. Is predicted to encode a protein with the following domain: Phosphorylation site. Is an ortholog of human NOL8 (nucleolar protein 8). WB:WBGene00010639 K07F5.15 Enriched in several structures, including NSM; coelomocyte; germ line; sensory neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and clk-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including rotenone; Rifampin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0390 and Protein of unknown function (DUF2462). Is an ortholog of human C19orf53 (chromosome 19 open reading frame 53). WB:WBGene00010640 K07F5.16 Predicted to be located in cytoplasm. Expressed in head neurons; hypodermis; intestine; and pharyngeal muscle cell. Is an ortholog of human DNAJC12 (DnaJ heat shock protein family (Hsp40) member C12). WB:WBGene00010641 crml-1 Enables GTPase activating protein binding activity. Involved in several processes, including axon guidance; negative regulation of Rac protein signal transduction; and regulation of axon extension involved in axon guidance. Located in plasma membrane. Expressed in several structures, including distal tip cell; epithelial cell; excretory canal; neurons; and vulva. Human ortholog(s) of this gene implicated in immunodeficiency 58. Is an ortholog of human CARMIL1 (capping protein regulator and myosin 1 linker 1); CARMIL2 (capping protein regulator and myosin 1 linker 2); and CARMIL3 (capping protein regulator and myosin 1 linker 3). WB:WBGene00010642 mks-6 Involved in non-motile cilium assembly and protein localization to ciliary transition zone. Located in ciliary transition zone and dendrite terminus. Expressed in ciliated neurons; head; and tail. Used to study ciliopathy. Human ortholog(s) of this gene implicated in several diseases, including Joubert syndrome 9; Meckel syndrome 6; and retinitis pigmentosa. Is an ortholog of human CC2D2A (coiled-coil and C2 domain containing 2A) and CC2D2B (coiled-coil and C2 domain containing 2B). WB:WBGene00010643 K07G5.4 Enriched in pm6 based on single-cell RNA-seq studies. Is affected by several genes including let-60; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00010644 K07G5.5 Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in membrane. WB:WBGene00010645 fecl-1 Predicted to enable ferrochelatase activity. Predicted to be involved in heme biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in colon adenocarcinoma; cutaneous porphyria; and erythropoietic protoporphyria. Is an ortholog of human FECH (ferrochelatase). WB:WBGene00010646 K08C7.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00010647 K08C7.4 Expressed in intestinal cell; neurons; and somatic nervous system. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010648 K08C7.6 Located in sarcoplasmic reticulum. WB:WBGene00010649 K08C7.7 Enriched in several structures, including PLM; body wall muscle cell; enteric muscle; head mesodermal cell; and rectal muscle based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00010650 K08C9.1 Enriched in I5 neuron; cholinergic neurons; germ line; retrovesicular ganglion; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nineteen chemicals including Ethanol; tryptophan; and rotenone based on RNA-seq and microarray studies. WB:WBGene00010651 K08C9.2 Expressed in spermatheca. WB:WBGene00010652 K08C9.5 Enriched in enteric muscle; g2; head mesodermal cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including age-1; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including aldicarb; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00010653 K08C9.6 Enriched in excretory duct; excretory pore; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies. WB:WBGene00010654 K08C9.7 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by CGP37157 and Diazinon based on RNA-seq and microarray studies. WB:WBGene00010655 K08D8.1 Predicted to be located in membrane. WB:WBGene00010656 K08D8.2 Predicted to be located in membrane. WB:WBGene00010657 K08D8.3 Enriched in ASER and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including rotenone; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00010658 K08D8.4 Involved in innate immune response. WB:WBGene00010659 K08D8.5 Involved in innate immune response and response to gamma radiation. Expressed in head neurons; intestine; and rectal gland cell. WB:WBGene00010660 K08D8.6 Located in membrane raft. WB:WBGene00010661 tyr-2 Enables dopachrome isomerase activity. Involved in negative regulation of apoptotic process. Expressed in hypodermis and uterine muscle. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human TYR (tyrosinase). WB:WBGene00010662 K08E3.2 Predicted to be located in cytoskeleton. WB:WBGene00010663 toca-2 Involved in several processes, including negative regulation of protein localization to adherens junction; positive regulation of egg-laying behavior; and regulation of cellular component organization. Located in several cellular components, including cell-cell junction; intracellular vesicle; and plasma membrane. Expressed in spermatheca and uterus. Human ortholog(s) of this gene implicated in Huntington's disease. Is an ortholog of human FNBP1 (formin binding protein 1); FNBP1L (formin binding protein 1 like); and TRIP10 (thyroid hormone receptor interactor 10). WB:WBGene00010664 dbn-1 Predicted to enable actin filament binding activity. Predicted to be involved in cellular component organization and positive regulation of neurogenesis. Predicted to be located in several cellular components, including actin cytoskeleton; plasma membrane bounded cell projection; and postsynapse. Human ortholog(s) of this gene implicated in Alzheimer's disease; Down syndrome; and cognitive disorder. Is an ortholog of human DBNL (drebrin like). WB:WBGene00010665 rml-1 Predicted to enable UTP:glucose-1-phosphate uridylyltransferase activity. Predicted to be involved in UDP-glucose metabolic process and glycogen metabolic process. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 83. Is an ortholog of human UGP2 (UDP-glucose pyrophosphorylase 2). WB:WBGene00010666 K08E4.2 Predicted to enable ceramide 1-phosphate binding activity and ceramide 1-phosphate transfer activity. Predicted to be involved in ceramide transport and intermembrane lipid transfer. Predicted to be located in cytosol. Is an ortholog of human CPTP (ceramide-1-phosphate transfer protein) and GLTPD2 (glycolipid transfer protein domain containing 2). WB:WBGene00010667 K08E4.3 Enriched in several structures, including GABAergic neurons; excretory cell; germ line; rectal epithelial cell; and rectum based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; rotenone; and stavudine based on microarray and RNA-seq studies. WB:WBGene00010669 bath-37 Predicted to be located in membrane. WB:WBGene00010670 tmed-1 Involved in IRE1-mediated unfolded protein response. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human TMED1 (transmembrane p24 trafficking protein 1) and TMED5 (transmembrane p24 trafficking protein 5). WB:WBGene00010671 eak-7 Located in plasma membrane. Expressed in body wall musculature; hypodermis; pharynx; and vulva. Is an ortholog of human MEAK7 (MTOR associated protein, eak-7 homolog). WB:WBGene00010672 K08E7.4 Enriched in amphid sheath cell and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; age-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00010673 K08E7.5 Enriched in OLL; PVD; germline precursor cell; and hypodermis based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-seven chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq; proteomic; and microarray studies. WB:WBGene00010674 K08E7.6 Enriched in several structures, including ABalapapapa; ABalapppapa; head mesodermal cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including multi-walled carbon nanotube; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010675 K08E7.8 Enriched in intestine; muscle cell; and somatic gonad precursor based on Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Zidovudine; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily; Leucine rich repeat; and Leucine-rich repeat. Is an ortholog of human LRRC20 (leucine rich repeat containing 20). WB:WBGene00010676 ctf-18 Predicted to enable DNA binding activity. Predicted to be located in nucleus. Is an ortholog of human CHTF18 (chromosome transmission fidelity factor 18). WB:WBGene00010677 gtbp-1 Predicted to enable mRNA binding activity. Located in cytoplasmic stress granule. Expressed widely. Is an ortholog of human G3BP1 (G3BP stress granule assembly factor 1) and G3BP2 (G3BP stress granule assembly factor 2). WB:WBGene00010678 K08F4.3 Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human SSR2 (signal sequence receptor subunit 2). WB:WBGene00010679 K08F4.5 Enriched in GABAergic neurons; NSM; amphid sheath cell; germ line; and in male based on RNA-seq and tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including Ethanol; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00010680 K08F4.12 Enriched in GABAergic neurons; dopaminergic neurons; excretory cell; intestine; and neurons based on tiling array studies. Is affected by several genes including mir-34; adr-1; and xpo-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Tunicamycin; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00010681 mak-1 Enables protein kinase activity and protein kinase binding activity. Involved in adult locomotory behavior and behavioral response to nicotine. Located in A band. Expressed in body wall muscle cell and tail. Human ortholog(s) of this gene implicated in patterned macular dystrophy 3. Is an ortholog of human MAPKAPK2 (MAPK activated protein kinase 2) and MAPKAPK3 (MAPK activated protein kinase 3). WB:WBGene00010682 nsph-1.1 Enriched in ABalpppppp; ABpraaappp; NSM; Y cell; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Cytosolic motility protein. WB:WBGene00010683 K08F8.7 Predicted to be located in membrane. WB:WBGene00010684 K08F9.1 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. Is an ortholog of several human genes including SLC2A11 (solute carrier family 2 member 11); SLC2A5 (solute carrier family 2 member 5); and SLC2A9 (solute carrier family 2 member 9). WB:WBGene00010685 aipl-1 Predicted to enable actin filament binding activity. Involved in actin filament organization and regulation of protein localization. Predicted to be located in cortical actin cytoskeleton. Expressed in body wall musculature; head neurons; intestine; and spermatheca. Is an ortholog of human WDR1 (WD repeat domain 1). WB:WBGene00010686 K08F9.3 Predicted to be located in membrane. WB:WBGene00010687 K08F9.4 Enriched in several structures, including I5 neuron; MSpaaapa; cholinergic neurons; germ line; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by nine chemicals including D-glucose; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00010688 srz-12 Predicted to be located in membrane. WB:WBGene00010689 K08H2.2 Enriched in ABalaaaarl and ABalaaaarr based on single-cell RNA-seq studies. Is affected by several genes including eat-2; tph-1; and dcr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Mercuric Chloride; rotenone; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00010690 K08H2.3 Enriched in ABplpppapa; ABprpppapa; NSM; germ line; and germline precursor cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on RNA-seq; tiling array; and microarray studies. Is affected by eighteen chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00010691 K08H2.4 Enriched in several structures, including FLP; body wall muscle cell; male distal tip cell; somatic gonad precursor; and terminal bulb based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00010692 K08H2.5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00010693 K08H2.7 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ASH; and anterior hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00010694 bgnt-1.5 Enriched in neurons and in male based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Alovudine; and stavudine based on RNA-seq studies. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A13. Human B4GAT1 enables glucuronosyltransferase activity. Is predicted to encode a protein with the following domain: Glycosyl-transferase for dystroglycan. Is an ortholog of human B4GAT1 (beta-1,4-glucuronyltransferase 1). WB:WBGene00010697 uda-1 Enables GDP phosphatase activity and UDP phosphatase activity. Involved in GDP metabolic process and UDP metabolic process. Located in cytoplasmic vesicle membrane. Is an ortholog of human ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive)) and ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6). WB:WBGene00010698 K08H10.6 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00010699 trpp-6 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in cis-Golgi network and trans-Golgi network. Predicted to be part of TRAPP complex. Is an ortholog of human TRAPPC6B (trafficking protein particle complex subunit 6B). WB:WBGene00010700 nipi-3 Predicted to enable mitogen-activated protein kinase kinase binding activity. Involved in antifungal innate immune response and positive regulation of gene expression. Predicted to be located in nucleus. Expressed in CAN; hypodermis; motor neurons; pharynx; and touch receptor neurons. Is an ortholog of human TRIB1 (tribbles pseudokinase 1). WB:WBGene00010701 ent-2 Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Located in plasma membrane. Expressed in intestine; isthmus; metacorpus; procorpus; and terminal bulb. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Is an ortholog of human SLC29A2 (solute carrier family 29 member 2) and SLC29A3 (solute carrier family 29 member 3). WB:WBGene00010702 usp-33 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process. Predicted to be located in cytosol and nucleus. Is an ortholog of human USP20 (ubiquitin specific peptidase 20) and USP33 (ubiquitin specific peptidase 33). WB:WBGene00010703 K09A9.6 Predicted to enable peptidyl-aspartic acid 3-dioxygenase activity. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in cholangiocarcinoma. Is an ortholog of human ASPH (aspartate beta-hydroxylase). WB:WBGene00010704 K09A11.1 Predicted to enable DNA binding activity; metal ion binding activity; and protein dimerization activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human ZBED1 (zinc finger BED-type containing 1). WB:WBGene00010705 cyp-14A1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and hereditary spastic paraplegia 56. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1). WB:WBGene00010706 cyp-14A2 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and hereditary spastic paraplegia 56. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1). WB:WBGene00010707 cyp-14A3 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and hereditary spastic paraplegia 56. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1). WB:WBGene00010708 phf-33 Predicted to enable metal ion binding activity. Predicted to be located in nucleus. WB:WBGene00010709 nol-9 Predicted to enable polynucleotide 5'-hydroxyl-kinase activity. Predicted to be involved in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleus. Is an ortholog of human NOL9 (nucleolar protein 9). WB:WBGene00010711 K09B11.4 Enriched in AVK and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; clk-1; and atfs-1 based on microarray and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Alovudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00010712 K09B11.5 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00010713 uso-1 Predicted to be involved in intracellular protein transport; membrane fusion; and vesicle-mediated transport. Predicted to be located in ER to Golgi transport vesicle membrane; Golgi stack; and endoplasmic reticulum. Is an ortholog of human USO1 (USO1 vesicle transport factor). WB:WBGene00010714 mam-3 Enriched in germline precursor cell; hypodermis; and tail hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; Nitric Oxide; and methylmercury hydroxide based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Concanavalin A-like lectin/glucanase domain superfamily. WB:WBGene00010715 K09C8.2 Predicted to be located in membrane. Expressed in seminal vesicle and vas deferens. WB:WBGene00010716 lge-1 Predicted to enable glucuronosyltransferase activity and xylosyltransferase activity. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A6 and muscular dystrophy-dystroglycanopathy type B6. Is an ortholog of human LARGE2 (LARGE xylosyl- and glucuronyltransferase 2). WB:WBGene00010717 K09C8.7 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00010718 K09C8.8 Enriched in AVE; excretory cell; excretory duct; and excretory pore based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00010719 K09E4.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00010720 algn-3 Predicted to enable dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Id. Is an ortholog of human ALG3 (ALG3 alpha-1,3- mannosyltransferase). WB:WBGene00010721 K09E4.3 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 16. Is an ortholog of human NDUFAF5 (NADH:ubiquinone oxidoreductase complex assembly factor 5). WB:WBGene00010722 K09E4.4 Enriched in neurons; retrovesicular ganglion; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq and microarray studies. Used to study mucopolysaccharidosis. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2V and mucopolysaccharidosis type IIIB. Is predicted to encode a protein with the following domains: Alpha-N-acetylglucosaminidase; Alpha-N-acetylglucosaminidase, C-terminal; Alpha-N-acetylglucosaminidase, tim-barrel domain; Glycoside hydrolase superfamily; Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain; and Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Is an ortholog of human NAGLU (N-acetyl-alpha-glucosaminidase). WB:WBGene00010723 cpg-7 Enriched in AIM; PLM; hypodermis; and seam cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including D-glucose; Cadmium Chloride; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00010724 K09E9.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00010725 ergi-3 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum; and membrane. Expressed in alimentary muscle and vm1. Human ortholog(s) of this gene implicated in lung adenocarcinoma. Is an ortholog of human ERGIC3 (ERGIC and golgi 3). WB:WBGene00010726 K09E9.3 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalpppppa; germ line; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by ten chemicals including Lithium Chloride; Alovudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00010727 K09G1.1 Predicted to be located in membrane. WB:WBGene00010728 K09G1.2 Predicted to be located in membrane. WB:WBGene00010730 ensa-1 Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of protein dephosphorylation. Predicted to be located in cytoplasm. Is an ortholog of human ENSA (endosulfine alpha). WB:WBGene00010731 K10C3.4 Predicted to be located in endoplasmic reticulum. Expressed in hermaphrodite distal tip cell; hypodermis; neurons; pharyngeal cell; and vulva. Human ortholog(s) of this gene implicated in nanophthalmos. Is an ortholog of human TMEM98 (transmembrane protein 98). WB:WBGene00010732 K10C3.5 Predicted to enable GTPase activity and ribosome binding activity. Predicted to be involved in cytosolic ribosome assembly. Predicted to be located in cytosol. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in Shwachman-Diamond syndrome. Is an ortholog of human EFL1 (elongation factor like GTPase 1). WB:WBGene00010733 C06B8.t1 No description available WB:WBGene00010734 parn-1 Enables 3'-5'-RNA exonuclease activity. Involved in RNA metabolic process and reproduction. Located in P granule. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 6 and spermatogenic failure 57. Is an ortholog of human PNLDC1 (PARN like ribonuclease domain containing exonuclease 1). WB:WBGene00010735 frpr-15 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00010736 istr-1 Predicted to be involved in protein localization. Is an ortholog of human IST1 (IST1 factor associated with ESCRT-III). WB:WBGene00010737 K10C8.4 Predicted to be located in membrane. WB:WBGene00010738 K10D3.4 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00010740 K10D3.6 Predicted to be located in membrane. WB:WBGene00010741 lgc-49 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00010742 clc-6 Predicted to be located in plasma membrane. Expressed in ciliated neurons and hypodermis. WB:WBGene00010743 K10D6.3 Enriched in ADEshL; ADEshR; G2; W cell; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00010744 K10D6.4 Enriched in several structures, including ABalppppppp; ABpraaapppp; head mesodermal cell; neurons; and pm6 based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by eleven chemicals including levamisole; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00010745 dod-17 Involved in innate immune response. WB:WBGene00010746 K10D11.2 Enriched in intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-nine chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00010747 K10D11.3 Enriched in OLL; PVD; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily and CUB-like domain. WB:WBGene00010748 K10D11.4 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including let-60; eat-2; and tbh-1 based on tiling array; RNA-seq; and microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00010749 K10D11.5 Predicted to be located in membrane. WB:WBGene00010750 K10D11.6 Enriched in OLL; PVD; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including Tunicamycin; D-glucose; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00010752 K10G4.3 Enriched in head mesodermal cell; intestine; and neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including bisphenol A; 4-bromodiphenyl ether; and stavudine based on RNA-seq and microarray studies. WB:WBGene00010753 K10G4.4 Is affected by several genes including clk-1; pgl-1; and lin-15B based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00010754 K10G4.5 Enriched in DB neuron and MSpaaapa based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Tunicamycin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00010755 vglu-2 Predicted to enable L-glutamate transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Predicted to be involved in several processes, including glutamatergic synaptic transmission; monoatomic anion transport; and neurotransmitter loading into synaptic vesicle. Predicted to be located in excitatory synapse. Expressed in AIAL; AIAR; hyp7 syncytium; uterine epithelial cell; and in male. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Is an ortholog of human SLC17A6 (solute carrier family 17 member 6); SLC17A7 (solute carrier family 17 member 7); and SLC17A8 (solute carrier family 17 member 8). WB:WBGene00010756 K10G9.2 Enriched in body wall musculature; head mesodermal cell; muscle cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on microarray; RNA-seq; and tiling array studies. Is affected by four chemicals including rotenone; stavudine; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010757 pad-2 Enables peptide-O-fucosyltransferase activity. Involved in protein O-linked fucosylation. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Expressed in body wall musculature; hermaphrodite gonad; hypodermis; and somatic nervous system. Used to study Down syndrome. Is an ortholog of human POFUT2 (protein O-fucosyltransferase 2). WB:WBGene00010758 vnut-1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in porokeratosis. Is an ortholog of human SLC17A9 (solute carrier family 17 member 9). WB:WBGene00010759 cysl-2 Enables L-3-cyanoalanine synthase activity and cysteine synthase activity. Involved in cysteine biosynthetic process from serine. Predicted to be located in cytoplasm. Expressed in hypodermis and pharynx. Used to study Down syndrome. WB:WBGene00010760 K10H10.4 Enriched in ASER; hypodermis; and pharyngeal muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-seven chemicals including 1-methylnicotinamide; nicotinic acid; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010761 K10H10.5 Predicted to be located in membrane. WB:WBGene00010762 K10H10.6 Enriched in ASER and RID based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on RNA-seq; tiling array; and microarray studies. Is affected by eight chemicals including aldicarb; methylmercuric chloride; and Mercuric Chloride based on microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and short chain dehydrogenase. Is an ortholog of human WWOX (WW domain containing oxidoreductase). WB:WBGene00010763 K10H10.7 Predicted to enable protein phosphatase 1 binding activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be located in nucleus. Is an ortholog of human PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11). WB:WBGene00010764 K10H10.9 Enriched in NSM and neurons based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; lin-15B; and set-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00010765 K10H10.10 Enriched in ABalpapaap; ABarappaap; RIS; Z1; and Z4 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including indole; Cadmium Chloride; and stavudine based on microarray and RNA-seq studies. WB:WBGene00010766 mrps-27 Predicted to be located in mitochondrion. Is an ortholog of human MRPS27 (mitochondrial ribosomal protein S27). WB:WBGene00010767 blos-9 Predicted to be located in lysosomal membrane. Predicted to be part of BORC complex. Is an ortholog of human BORCS8 (BLOC-1 related complex subunit 8). WB:WBGene00010768 K11D2.1 Enriched in hypodermis and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by five chemicals including hydrogen sulfide; sodium arsenite; and paraquat based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; Regulator of chromosome condensation (RCC1) repeat; and Regulator of chromosome condensation, RCC1. Is an ortholog of human RCCD1 (RCC1 domain containing 1). WB:WBGene00010769 asah-1 Predicted to enable N-acylsphingosine amidohydrolase activity. Predicted to be involved in fatty acid metabolic process and sphingolipid metabolic process. Predicted to be located in extracellular region and lysosome. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis; sphingolipidosis; and spinal muscular atrophy with progressive myoclonic epilepsy. Is an ortholog of human ASAH1 (N-acylsphingosine amidohydrolase 1). WB:WBGene00010770 K11D2.4 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of human ZNF707 (zinc finger protein 707) and ZNF746 (zinc finger protein 746). WB:WBGene00010771 mter-4 Predicted to enable double-stranded DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of human MTERF4 (mitochondrial transcription termination factor 4). WB:WBGene00010772 K11D9.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00010773 K11E4.1 Predicted to be involved in lipid metabolic process. WB:WBGene00010774 shc-3 Enriched in ABplapaaap; ABprapaaap; URX; dopaminergic neurons; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including dpy-10; elt-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including stavudine; Zidovudine; and Cadmium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: SH2 domain superfamily. WB:WBGene00010775 poml-1 Enables protein folding chaperone. Involved in protein maturation by protein folding. Located in rough endoplasmic reticulum. Expressed in neurons. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); eye disease (multiple); and hematologic cancer (multiple). Is an ortholog of human PON1 (paraoxonase 1); PON2 (paraoxonase 2); and PON3 (paraoxonase 3). WB:WBGene00010776 pix-1 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in gonad morphogenesis; inductive cell migration; and neuron migration. Located in anchoring junction; cell periphery; and cytoplasm. Expressed in hermaphrodite gonad; hypodermis; and somatic gonad precursor. Human ortholog(s) of this gene implicated in intellectual disability. Is an ortholog of human ARHGEF6 (Rac/Cdc42 guanine nucleotide exchange factor 6). WB:WBGene00010777 C06B8.t2 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00010778 gpdh-2 Predicted to enable glycerol-3-phosphate dehydrogenase (quinone) activity and glycerol-3-phosphate dehydrogenase [NAD(P)+] activity. Involved in intracellular accumulation of glycerol. Predicted to be located in cytosol. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Expressed in excretory cell and hypodermis. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Is an ortholog of human GPD1 (glycerol-3-phosphate dehydrogenase 1) and GPD1L (glycerol-3-phosphate dehydrogenase 1 like). WB:WBGene00010779 K11H3.2 Enriched in amphid sheath cell; germ line; muscle cell; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00010780 K11H3.3 Predicted to enable citrate secondary active transmembrane transporter activity. Predicted to be involved in mitochondrial citrate transmembrane transport. Predicted to be located in mitochondrion. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in combined D-2- and L-2-hydroxyglutaric aciduria and congenital myasthenic syndrome. Is an ortholog of human SLC25A1 (solute carrier family 25 member 1). WB:WBGene00010781 K11H3.4 Enriched in AVJ; Psub1; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq studies. WB:WBGene00010782 K11H3.5 Enriched in intestine and neurons based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00010783 mrpl-36 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL36 (mitochondrial ribosomal protein L36). WB:WBGene00010784 twk-48 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in migraine. Is an ortholog of human KCNK18 (potassium two pore domain channel subfamily K member 18). WB:WBGene00010785 top-2 Predicted to enable DNA binding activity; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; and ion binding activity. Involved in mitotic sister chromatid separation. Predicted to be located in nucleus. Expressed in embryonic cell; germ cell; and somatic cell. Human ortholog(s) of this gene implicated in several diseases, including cervix uteri carcinoma in situ; penile benign neoplasm; and urinary system cancer (multiple). Is an ortholog of human TOP2B (DNA topoisomerase II beta). WB:WBGene00010786 K12D12.4 Predicted to be located in membrane. WB:WBGene00010787 K12D12.5 Predicted to enable RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer. WB:WBGene00010788 sulp-4 Enables chloride transmembrane transporter activity; oxalate transmembrane transporter activity; and sulfate transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Located in apical plasma membrane. Expressed in excretory cell. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 61. Is an ortholog of human SLC26A5 (solute carrier family 26 member 5) and SLC26A6 (solute carrier family 26 member 6). WB:WBGene00010789 sulp-5 Predicted to enable salt transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Located in apical plasma membrane. Expressed in excretory canal and seam cell. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 61; calcium oxalate nephrolithiasis; and spermatogenic failure 3. Is an ortholog of human SLC26A5 (solute carrier family 26 member 5) and SLC26A6 (solute carrier family 26 member 6). WB:WBGene00010790 adh-1 Predicted to enable alcohol dehydrogenase (NAD+) activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in cytoplasm. Expressed in hypodermis; muscle cell; and neurons. WB:WBGene00010791 sodh-2 Predicted to enable alcohol dehydrogenase (NAD+) activity. Predicted to be located in cytoplasm. WB:WBGene00010792 K12G11.6 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00010793 nspg-9 Enriched in head mesodermal cell; intestine; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-five chemicals including methylmercuric chloride; rotenone; and mianserin based on microarray and RNA-seq studies. WB:WBGene00010794 dld-1 Predicted to enable dihydrolipoyl dehydrogenase activity and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to be located in mitochondrion. Predicted to be part of oxoglutarate dehydrogenase complex. Human ortholog(s) of this gene implicated in maple syrup urine disease. Is an ortholog of human DLD (dihydrolipoamide dehydrogenase). WB:WBGene00010795 M01A8.1 Predicted to be located in membrane. WB:WBGene00010796 clip-1 Enables microtubule binding activity. Involved in nucleus localization and nucleus organization. Located in nuclear envelope. Expressed in pharynx. WB:WBGene00010797 srbc-75 Predicted to be located in membrane. WB:WBGene00010798 srbc-76 Predicted to be located in membrane. WB:WBGene00010799 chil-12 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00010800 srsx-37 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in ADLL; ADLR; and AWC-OFF. Is an ortholog of several human genes including OR2M4 (olfactory receptor family 2 subfamily M member 4); OR5H1 (olfactory receptor family 5 subfamily H member 1); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00010801 M01B2.8 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by D-glucose; silicon dioxide nanoparticle; and Doxycycline based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00010802 srsx-39 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00010803 M01B2.10 Predicted to be located in cytoplasm. Is an ortholog of human PHYHIP (phytanoyl-CoA 2-hydroxylase interacting protein) and PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like). WB:WBGene00010804 M01E5.1 Enriched in AIBL; AIBR; NSM; VA12; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Tunicamycin; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00010805 M01E5.2 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in mitochondrion. Is an ortholog of human MTG2 (mitochondrial ribosome associated GTPase 2). WB:WBGene00010806 M01E5.3 Enriched in AFD; OLL; PVD; and germ line based on microarray and RNA-seq studies. Is affected by several genes including dpy-10; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Zidovudine; silicon dioxide nanoparticle; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Uncharacterised protein family UPF0561. WB:WBGene00010807 M01E5.4 Located in cytoplasm. Is an ortholog of human C2orf68 (chromosome 2 open reading frame 68). WB:WBGene00010808 sepa-1 Enables protein self-association and protein-macromolecule adaptor activity. Involved in autophagy. Located in cytoplasm. Expressed in head; intestine; and tail. WB:WBGene00010809 lias-1 Predicted to enable lipoate synthase activity. Predicted to be involved in lipoate biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Is an ortholog of human LIAS (lipoic acid synthetase). WB:WBGene00010810 M01F1.4 Predicted to be located in membrane. Is an ortholog of human TMEM245 (transmembrane protein 245). WB:WBGene00010811 hmit-1.3 Predicted to enable myo-inositol:proton symporter activity. Predicted to be involved in myo-inositol transport and transmembrane transport. Located in apical plasma membrane. Expressed in amphid sheath cell; head; and phasmid sheath cell. Is an ortholog of human SLC2A13 (solute carrier family 2 member 13). WB:WBGene00010812 mrpl-35 Predicted to be located in mitochondrion. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human MRPL35 (mitochondrial ribosomal protein L35). WB:WBGene00010813 pitp-1 Predicted to enable phospholipid binding activity and phospholipid transporter activity. Predicted to be involved in intermembrane lipid transfer and phospholipid transport. Located in ciliary transition zone and synapse. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in cone-rod dystrophy 5. Is an ortholog of human PITPNM1 (phosphatidylinositol transfer protein membrane associated 1). WB:WBGene00010814 M01F1.8 Enriched in germ line; germline precursor cell; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00010815 M01F1.9 Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be located in Golgi membrane. Predicted to be part of Ric1-Rgp1 guanyl-nucleotide exchange factor complex. Is an ortholog of human RGP1 (RGP1 homolog, RAB6A GEF complex partner 1). WB:WBGene00010817 M01G12.2 Enriched in neurons based on RNA-seq studies. Is affected by clk-1 and sir-2.1 based on microarray studies. Is affected by Mercuric Chloride and nitroguanidine based on microarray studies. Is predicted to encode a protein with the following domains: Serpin superfamily, domain 2; Serpin (serine protease inhibitor); Serpin superfamily; and Serpin domain. WB:WBGene00010818 srt-21 Is affected by several genes including eat-2; fbf-1; and ain-1 based on RNA-seq and microarray studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00010819 M01G12.5 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sma-3; hda-2; and etr-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Mercuric Chloride; Chlorpyrifos; and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: Serpin superfamily, domain 2 and Serpin superfamily. WB:WBGene00010820 M01G12.6 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and glh-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00010821 M01G12.7 Predicted to enable mRNA 5'-diphosphatase activity. Predicted to be involved in NAD-cap decapping; nuclear-transcribed mRNA catabolic process; and nucleic acid phosphodiester bond hydrolysis. Predicted to be located in cytosol and nucleus. WB:WBGene00010822 M01G12.9 Predicted to enable mRNA 5'-diphosphatase activity. Predicted to be involved in NAD-cap decapping; nuclear-transcribed mRNA catabolic process; and nucleic acid phosphodiester bond hydrolysis. Predicted to be located in cytosol and nucleus. WB:WBGene00010823 M01G12.10 Is affected by several genes including rrf-3; qui-1; and etr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00010824 M01G12.11 Is affected by cyc-1; clk-1; and nhr-25 based on microarray studies. WB:WBGene00010825 M01G12.14 Predicted to enable mRNA 5'-diphosphatase activity. Predicted to be involved in NAD-cap decapping; nuclear-transcribed mRNA catabolic process; and nucleic acid phosphodiester bond hydrolysis. Predicted to be located in cytosol and nucleus. WB:WBGene00010827 txt-19 Predicted to be located in membrane. Expressed in AIYL and AIYR. WB:WBGene00010828 M02B1.3 Predicted to be involved in membrane organization and phospholipid homeostasis. Located in plasma membrane. Is an ortholog of human TLCD1 (TLC domain containing 1) and TLCD2 (TLC domain containing 2). WB:WBGene00010829 M02B1.4 Predicted to be located in membrane. WB:WBGene00010830 appg-1 Enriched in GABAergic neurons; anterior arcade cell; intestine; and posterior arcade cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00010831 idpp-4 Enriched in anterior arcade cell and intestine based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nineteen chemicals including methylmercury hydroxide; methylmercuric chloride; and sodium arsenite based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1096 and Protein of unknown function (DUF1096). WB:WBGene00010832 idpp-8 Enriched in arcade cell; excretory gland cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including indole; Sodium Chloride; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00010833 M03B6.1 Enriched in coelomocyte; muscle cell; neurons; and ventral nerve cord based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by seventeen chemicals including 1-methylnicotinamide; Tunicamycin; and D-glucopyranose based on RNA-seq and microarray studies. WB:WBGene00010834 mct-3 Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Expressed in hypodermis. Is an ortholog of human SLC16A14 (solute carrier family 16 member 14); SLC16A4 (solute carrier family 16 member 4); and SLC16A9 (solute carrier family 16 member 9). WB:WBGene00010835 M03B6.3 Enriched in hypodermis; intestine; seam cell; and tail hypodermis based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including methylmercury hydroxide; methylmercuric chloride; and D-glucose based on RNA-seq; microarray; and proteomic studies. WB:WBGene00010836 M03B6.4 Predicted to be located in membrane. WB:WBGene00010837 M03B6.5 Predicted to be located in membrane. WB:WBGene00010838 M03C11.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Is an ortholog of human STK32A (serine/threonine kinase 32A); STK32B (serine/threonine kinase 32B); and STK32C (serine/threonine kinase 32C). WB:WBGene00010839 chl-1 Predicted to enable DNA helicase activity. Involved in positive regulation of cell population proliferation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Warsaw breakage syndrome. Is an ortholog of human DDX11 (DEAD/H-box helicase 11). WB:WBGene00010840 M03C11.3 Enriched in several structures, including ABalpppapa; ABplpaappa; ABplpppaaa; AVK; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including isp-1; lin-28; and unc-30 based on microarray; RNA-seq; and proteomic studies. Is affected by five chemicals including rotenone; Zidovudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010842 ymel-1 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in optic atrophy 11. Is an ortholog of human YME1L1 (YME1 like 1 ATPase). WB:WBGene00010843 M03C11.6 Enriched in several structures, including ABalappaap; ABplpaaaap; ABprpaaaap; germ line; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00010844 prp-3 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa 18. Is an ortholog of human PRPF3 (pre-mRNA processing factor 3). WB:WBGene00010845 smrd-1 Predicted to enable ATP-dependent activity, acting on DNA; DNA binding activity; and chromatin binding activity. Predicted to be involved in DNA repair and chromatin remodeling. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in BASAN syndrome and adermatoglyphia. Is an ortholog of human SMARCAD1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1). WB:WBGene00010846 M04B2.2 Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. Is an ortholog of human THUMPD3 (THUMP domain containing 3). WB:WBGene00010847 M04B2.4 Predicted to enable oxidoreductase activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 19. Is an ortholog of human FOXRED1 (FAD dependent oxidoreductase domain containing 1). WB:WBGene00010848 M04B2.6 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00010849 M04B2.7 Predicted to be located in membrane. WB:WBGene00010850 M04C3.1 Predicted to enable ATP binding activity and ATP-dependent chromatin remodeler activity. Predicted to be involved in chromatin remodeling. WB:WBGene00010851 M04C3.2 Predicted to enable ATP binding activity and ATP-dependent chromatin remodeler activity. Involved in innate immune response. WB:WBGene00010853 M04C7.2 No description available WB:WBGene00010854 M04C7.3 Enriched in arcade cell; neurons; pharyngeal-intestinal valve cell; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and adsorbable organic bromine compound based on RNA-seq and microarray studies. WB:WBGene00010855 M04C7.4 Predicted to be located in membrane. WB:WBGene00010856 M04C9.1 Predicted to enable cysteine-type peptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human PGPEP1L (pyroglutamyl-peptidase I like). WB:WBGene00010857 M04C9.2 Predicted to enable cysteine-type peptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human PGPEP1L (pyroglutamyl-peptidase I like). WB:WBGene00010858 M04C9.3 Predicted to enable cysteine-type peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human PGPEP1L (pyroglutamyl-peptidase I like). WB:WBGene00010859 M04C9.4 Enriched in ASER; intestine; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including tryptophan; rotenone; and levamisole based on microarray and RNA-seq studies. WB:WBGene00010862 M04D8.4 Predicted to be located in membrane. WB:WBGene00010863 M04D8.5 Predicted to be located in membrane. WB:WBGene00010864 xbx-3 Predicted to be located in membrane. Expressed in neurons. WB:WBGene00010865 M04D8.7 Predicted to be located in membrane. WB:WBGene00010866 M04D8.8 Predicted to be located in membrane. WB:WBGene00010867 ifbp-1 Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in common variable immunodeficiency 14 and neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures. Is an ortholog of human IRF2BP2 (interferon regulatory factor 2 binding protein 2) and IRF2BPL (interferon regulatory factor 2 binding protein like). WB:WBGene00010868 somi-1 Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in cell differentiation. Located in nucleus. Expressed in several structures, including gonad; hypodermal cell; intestine; neurons; and vulval precursor cell. WB:WBGene00010869 M05B5.1 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00010870 let-522 Predicted to be located in membrane. Expressed in pharynx. WB:WBGene00010871 M05B5.3 Predicted to be located in membrane. WB:WBGene00010872 plag-15 Predicted to enable O-acyltransferase activity. Predicted to be involved in lipid metabolic process. Expressed in hypodermis; intestine; neuronal sheath cell; pharynx; and tail. Human ortholog(s) of this gene implicated in Norum disease and arteriosclerosis. Is an ortholog of human PLA2G15 (phospholipase A2 group XV). WB:WBGene00010873 trpa-2 Predicted to be located in membrane. Expressed in ASEL; ASER; and neurons. WB:WBGene00010874 M05D6.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00010875 M05D6.2 Predicted to be involved in signal transduction. Is an ortholog of human TCP11 (t-complex 11); TCP11L1 (t-complex 11 like 1); and TCP11L2 (t-complex 11 like 2). WB:WBGene00010876 M05D6.3 Predicted to enable protein tyrosine phosphatase activity. Human ortholog(s) of this gene implicated in multiple sclerosis and severe combined immunodeficiency. Is an ortholog of human PTPRC (protein tyrosine phosphatase receptor type C). WB:WBGene00010877 lact-4 Enriched in several structures, including ABalppppppa; ABpraaapppa; coelomocyte; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including Tunicamycin; mianserin; and D-glucose based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Beta-lactamase; Beta-lactamase/transpeptidase-like; and Beta-lactamase-related. WB:WBGene00010878 M05D6.5 Predicted to be involved in mitochondrial respirasome assembly. Located in endoplasmic reticulum. WB:WBGene00010879 taap-1 Predicted to be located in membrane. Is an ortholog of human FAM162A (family with sequence similarity 162 member A) and FAM162B (family with sequence similarity 162 member B). WB:WBGene00010880 M05D6.8 Enriched in AVG; RIM; command interneuron; pharyngeal cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; mex-3; and mex-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Rifampin; Sirolimus; and stearic acid based on RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00010881 M05D6.9 Enriched in several structures, including M cell; anal sphincter muscle; g1; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00010882 atg-7 Predicted to enable Atg12 activating enzyme activity and Atg8 activating enzyme activity. Involved in several processes, including dauer larval development; determination of adult lifespan; and positive regulation of autophagosome assembly. Predicted to be located in phagophore assembly site. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 31. Is an ortholog of human ATG7 (autophagy related 7). WB:WBGene00010883 M7.7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00010884 M7.8 Predicted to enable N-acetyltransferase activity. WB:WBGene00010885 srlf-18 Enriched in body wall musculature; germ line; male-specific anatomical entity; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00010886 srlf-17 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00010887 M7.12 Predicted to enable N-acetyltransferase activity. WB:WBGene00010888 dlc-2 Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based process. Predicted to be located in cytoplasm and microtubule. Predicted to be part of cytoplasmic dynein complex. Expressed in head muscle; intestine; neurons; and pharyngeal muscle cell. WB:WBGene00010889 M18.3 Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity. Predicted to be involved in asparagine biosynthetic process. Located in cytoplasm. Is an ortholog of human ASNSD1 (asparagine synthetase domain containing 1). WB:WBGene00010890 ddb-1 Predicted to enable DNA binding activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm; nucleus; and site of double-strand break. Expressed in several structures, including P1.p; P2.p; P5.ppp; P7.paa; and rectum. Used to study xeroderma pigmentosum. Is an ortholog of human DDB1 (damage specific DNA binding protein 1). WB:WBGene00010891 M18.6 Predicted to be involved in protein ubiquitination. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 2. Is an ortholog of human CRBN (cereblon). WB:WBGene00010892 dhhc-6 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Is an ortholog of human ZDHHC6 (zinc finger DHHC-type palmitoyltransferase 6). WB:WBGene00010893 cutl-9 Predicted to be located in membrane. WB:WBGene00010894 M28.2 Is affected by several genes including daf-2; eat-2; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00010895 M28.4 Predicted to be located in membrane. WB:WBGene00010896 snu-13 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome; maturation of LSU-rRNA; and maturation of SSU-rRNA. Predicted to be located in nucleolus. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human SNU13 (small nuclear ribonucleoprotein 13). WB:WBGene00010897 lact-3 Enriched in MSpaaaaa; OLL; PVD; and intestine based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eleven chemicals including aldicarb; Cry5B; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Beta-lactamase; Beta-lactamase/transpeptidase-like; and Beta-lactamase-related. WB:WBGene00010898 nphp-1 Involved in several processes, including determination of adult lifespan; male mating behavior; and non-motile cilium assembly. Located in cilium. Expressed in ciliated neurons; cloacal ganglion; postcloacal sensillum; and sensory neurons. Used to study nephronophthisis. Human ortholog(s) of this gene implicated in several diseases, including Joubert syndrome 4; Senior-Loken syndrome; and nephronophthisis 1. Is an ortholog of human NPHP1 (nephrocystin 1). WB:WBGene00010899 M28.8 Predicted to be located in membrane. WB:WBGene00010900 M28.9 Predicted to be located in membrane. WB:WBGene00010901 M28.10 Enriched in head mesodermal cell and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including manganese chloride; nicotine; and stavudine based on RNA-seq; proteomic; and microarray studies. WB:WBGene00010902 M79.2 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Located in striated muscle dense body. WB:WBGene00010904 ugt-62 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00010905 mrps-34 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 32. Is an ortholog of human MRPS34 (mitochondrial ribosomal protein S34). WB:WBGene00010906 M88.3 Enriched in several structures, including I5 neuron; ciliated neurons; germ line; interfacial epithelial cell; and rect_D based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00010907 M88.4 Enriched in DVA; anterior hypodermis; interfacial epithelial cell; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; bortezomib; and paraquat based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PH-like domain superfamily and PTB/PI domain. WB:WBGene00010908 imph-1 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in nervous system development and regulation of gene expression. Predicted to be located in cytosol and nucleus. Expressed in tail. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human IGF2BP1 (insulin like growth factor 2 mRNA binding protein 1); IGF2BP2 (insulin like growth factor 2 mRNA binding protein 2); and IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3). WB:WBGene00010909 cisd-3.1 Predicted to enable 2 iron, 2 sulfur cluster binding activity. Predicted to be involved in protein maturation by [2Fe-2S] cluster transfer. Predicted to be located in mitochondrion. Is an ortholog of human CISD3 (CDGSH iron sulfur domain 3). WB:WBGene00010910 M106.2 Enriched in several structures, including ABalppappa; germ line; head mesodermal cell; head neurons; and pm6 based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; sir-2.1; and npr-1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by five chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00010911 M106.3 Predicted to enable 15-oxoprostaglandin 13-oxidase activity. Predicted to be involved in prostaglandin metabolic process. Predicted to be located in cytoplasm. Expressed in head and tail. Is an ortholog of human PTGR2 (prostaglandin reductase 2). WB:WBGene00010912 gmps-1 Predicted to enable GMP synthase activity. Predicted to be involved in GMP biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in acute myelomonocytic leukemia. Is an ortholog of human GMPS (guanine monophosphate synthase). WB:WBGene00010913 M110.3 Predicted to enable zinc ion binding activity. Is an ortholog of human MARCHF5 (membrane associated ring-CH-type finger 5). WB:WBGene00010914 M110.6 No description available WB:WBGene00010915 M110.7 Predicted to enable lysophospholipase activity. Predicted to be involved in lipid catabolic process. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in several diseases, including Boucher-Neuhauser syndrome; Laurence-Moon syndrome; and Oliver-McFarlane syndrome. Is an ortholog of human PNPLA6 (patatin like phospholipase domain containing 6) and PNPLA7 (patatin like phospholipase domain containing 7). WB:WBGene00010916 M110.8 Predicted to be located in membrane. WB:WBGene00010917 M110.9 Enriched in several structures, including ABalaappppa; MSpppaaa; ciliated neurons; g1; and head mesodermal cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including glycine; cholesterol; and cadmium based on RNA-seq and microarray studies. WB:WBGene00010918 M117.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00010919 M117.3 Predicted to be involved in signal transduction. Predicted to be located in cytoplasm. WB:WBGene00010920 M117.4 Enriched in amphid neurons; germ line; intestine; sensory neurons; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00010921 fbxb-4 Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including hydrogen sulfide; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00010922 M142.5 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on proteomic; RNA-seq; and microarray studies. Is affected by four chemicals including rotenone; stavudine; and antimycin based on RNA-seq studies. Is predicted to encode a protein with the following domains: LSM12, anticodon-binding domain; Anticodon-binding domain; and Protein Lsm12-like. Is an ortholog of human LSM12 (LSM12 homolog). WB:WBGene00010923 rle-1 Enables ubiquitin-protein transferase activity. Involved in determination of adult lifespan; response to heat; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasmic stress granule. Expressed in several structures, including intestine. Is an ortholog of human RC3H1 (ring finger and CCCH-type domains 1). WB:WBGene00010924 pycr-1 Predicted to enable pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIB; autosomal recessive cutis laxa type IIIB; and hypomyelinating leukodystrophy 10. Is an ortholog of human PYCR1 (pyrroline-5-carboxylate reductase 1). WB:WBGene00010925 mfsd-11 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00010926 M153.3 Enriched in anterior hypodermis; arcade cell; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00010927 clec-259 Enriched in body wall muscle cell; pharyngeal cell; and pharyngeal-intestinal valve based on tiling array and single-cell RNA-seq studies. Is affected by several genes including lin-15B; mex-3; and set-2 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00010928 clec-258 Enriched in several structures, including ABalpapppa; ABarapappa; ABplpapppa; mechanosensory neurons; and pharynx based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twenty-seven chemicals including 1-methylnicotinamide; rotenone; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00010929 srt-45 Predicted to be located in membrane. Expressed in AWC-OFF and head neurons. WB:WBGene00010930 srt-46 Enriched in muscle cell based on microarray studies. Is affected by cyc-1 and eat-2 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00010931 M162.5 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00010932 M162.6 Enriched in body wall muscle cell and hypodermis based on tiling array studies. Is affected by several genes including let-60; eat-2; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including tryptophan; allantoin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00010933 M162.7 Enriched in germ line based on proteomic and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Zidovudine; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function and Domain of unknown function WSN. WB:WBGene00010934 fbxa-118 Enriched in AVDL; AVDR; head mesodermal cell; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by five chemicals including Mercuric Chloride; multi-walled carbon nanotube; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00010935 M163.1 Enriched in several structures, including MSaaaaapa; MSaapaapa; muscle cell; sensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; rotenone; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00010936 ztf-14 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in central nervous system development; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00010937 M163.5 Enriched in ABalppppppp; ABpraaapppp; and neurons based on tiling array; single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; pgl-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by tryptophan; resveratrol; and fluoranthene based on microarray studies. WB:WBGene00010938 M163.6 Enriched in AMsoL; AMsoR; NSM; and hyp3 based on tiling array and single-cell RNA-seq studies. Is affected by eat-2; daf-2; and mex-1 based on RNA-seq and microarray studies. Is affected by Microcystin-LR based on microarray studies. WB:WBGene00010939 M163.7 Predicted to be located in membrane. WB:WBGene00010940 M163.8 Enriched in several structures, including ABalpapaap; ABalppappa; SIA; amphid neurons; and g1 based on single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00010941 gss-1 Predicted to enable glutathione binding activity and glutathione synthase activity. Predicted to be involved in glutathione biosynthetic process. Predicted to be located in cytosol. Expressed in head. Human ortholog(s) of this gene implicated in Alzheimer's disease; glutathione synthetase deficiency of erythrocytes; and glutatione synthetase deficiency with 5-oxoprolinuria. Is an ortholog of human GSS (glutathione synthetase). WB:WBGene00010942 chch-3 Predicted to be involved in inner mitochondrial membrane organization. Predicted to be located in mitochondrial inner membrane. Predicted to be part of MICOS complex. Is an ortholog of human CHCHD3 (coiled-coil-helix-coiled-coil-helix domain containing 3). WB:WBGene00010943 M176.4 Predicted to enable hydrolase activity. Located in endoplasmic reticulum. Is an ortholog of human TMEM86A (transmembrane protein 86A) and TMEM86B (transmembrane protein 86B). WB:WBGene00010944 M176.5 Expressed in neurons and pharynx. WB:WBGene00010945 chil-13 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00010946 M176.10 Enriched in male-specific anatomical entity; neurons; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; rrf-3; and lin-4 based on RNA-seq and microarray studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00010947 M176.11 Predicted to be located in membrane. WB:WBGene00010948 M195.2 Enriched in RID; cholinergic neurons; pharyngeal-intestinal valve; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-three chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00010949 M195.4 Is affected by several genes including sir-2.1; unc-30; and ubc-9 based on microarray and RNA-seq studies. Is affected by Doxycycline; paraquat; and dafa#1 based on RNA-seq and microarray studies. WB:WBGene00010950 srt-44 Predicted to be located in membrane. WB:WBGene00010951 M199.2 Predicted to be located in cytoskeleton. WB:WBGene00010952 clec-188 Enriched in CEM; HOB; IL2 neuron; and ray neuron type B based on RNA-seq studies. Is affected by drh-3 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00010953 clec-190 Enriched in cephalic sheath cell and dopaminergic neurons based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by twenty-three chemicals including 1-methylnicotinamide; rotenone; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C-type lectin fold. WB:WBGene00010954 clec-189 Is affected by rsr-2; met-2; and spr-5 based on tiling array and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00010955 M199.7 Enriched in ABaraapapaa; ABaraapppaa; MSaapaapa; MSpapaapa; and pharyngeal muscle cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; mex-3; and mex-1 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00010956 M199.8 Enriched in head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by clk-1; daf-2; and eat-2 based on microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00010957 nduo-6 Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be located in mitochondrial membrane and respirasome. WB:WBGene00010958 ndfl-4 Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be located in mitochondrial membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. WB:WBGene00010959 nduo-1 Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in aerobic respiration. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. WB:WBGene00010960 atp-6 Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex. WB:WBGene00010961 nduo-2 Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. WB:WBGene00010962 ctc-3 Predicted to enable electron transfer activity. Predicted to contribute to cytochrome-c oxidase activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. WB:WBGene00010963 nduo-4 Predicted to enable ubiquinone binding activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in aerobic respiration and electron transport coupled proton transport. Predicted to be located in mitochondrial membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. WB:WBGene00010964 ctc-1 Predicted to enable heme binding activity and metal ion binding activity. Predicted to contribute to cytochrome-c oxidase activity. Predicted to be involved in electron transport coupled proton transport and mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. WB:WBGene00010965 ctc-2 Predicted to enable copper ion binding activity. Predicted to contribute to cytochrome-c oxidase activity. Predicted to be involved in ATP synthesis coupled electron transport. Predicted to be located in mitochondrial inner membrane and respirasome. WB:WBGene00010966 nduo-3 Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be located in mitochondrial membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. WB:WBGene00010967 nduo-5 Predicted to enable NADH dehydrogenase activity. Predicted to be involved in electron transport coupled proton transport. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. WB:WBGene00010968 R01E6.2 Predicted to be located in extracellular region. WB:WBGene00010969 R01E6.5 Expressed in spicule neurons and vulva. WB:WBGene00010970 glb-20 Predicted to enable heme binding activity and oxygen binding activity. Expressed in body wall musculature; enteric muscle; head neurons; and somatic nervous system. WB:WBGene00010971 R01E6.7 Enriched in ABplppppaa; ABprppppaa; neurons; and retrovesicular ganglion based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and let-60 based on RNA-seq and microarray studies. Is affected by five chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00010972 R01H10.4 Enriched in several structures, including ALN; Caaaaa; Caaaap; Caaapa; and neuronal sheath cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Uncharacterized protein T19C3.2-like. WB:WBGene00010973 rip-1 Part of DNA recombinase mediator complex. WB:WBGene00010974 bbs-5 Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in cilium assembly and intracellular transport. Located in cilium. Expressed in head; neurons; outer labial neurons; and tail. Used to study Bardet-Biedl syndrome and ciliopathy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 5. Is an ortholog of human BBS5 (Bardet-Biedl syndrome 5). WB:WBGene00010975 inpp-4B Predicted to enable phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity. Predicted to be involved in phosphatidylinositol-3-phosphate biosynthetic process. Predicted to be located in cytoplasm. Is an ortholog of human INPP4B (inositol polyphosphate-4-phosphatase type II B). WB:WBGene00010976 R02D5.1 Enriched in several structures, including ABarppaapp; ABarpppapp; ABplapaaaap; ABplapaaapa; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eleven chemicals including 1-methylnicotinamide; Cry5B; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00010977 R02D5.3 Predicted to be located in membrane. Predicted to be part of acetylcholine-gated channel complex. WB:WBGene00010978 R02D5.4 Enriched in neurons and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by ins-11; drh-3; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00010979 R02D5.6 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00010980 R02D5.7 Predicted to be located in membrane. WB:WBGene00010981 blos-8 Predicted to be located in lysosomal membrane. Predicted to be part of BORC complex. Is an ortholog of human BORCS7 (BLOC-1 related complex subunit 7). WB:WBGene00010982 flp-32 Expressed in head neurons and pharyngeal motor neurons. WB:WBGene00010983 mocs-1 Predicted to enable Mo-molybdopterin cofactor sulfurase activity. Predicted to be involved in molybdopterin cofactor metabolic process. Expressed in amphid sheath cell; head; and socket cell. Used to study autism spectrum disorder. Is an ortholog of human MOCOS (molybdenum cofactor sulfurase). WB:WBGene00010984 nkat-3 Predicted to enable kynurenine-oxoglutarate transaminase activity. Predicted to be involved in L-kynurenine metabolic process and biosynthetic process. Predicted to be located in mitochondrion. Expressed in gonad; pharyngeal muscle cell; and tail. Is an ortholog of human KYAT1 (kynurenine aminotransferase 1). WB:WBGene00010985 R03A10.5 Enriched in several structures, including AFD; neuronal sheath cell; tail hypodermis; tail precursor cell; and ventral cord blast cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including manganese chloride; 4-bromodiphenyl ether; and levamisole based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: CRAL-TRIO lipid binding domain; CRAL-TRIO lipid binding domain superfamily; and CRAL/TRIO domain. WB:WBGene00010986 sprr-1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00010987 R03C1.1 Enriched in arcade cell; neurons; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including aldicarb; hydrogen sulfide; and Ethanol based on microarray and RNA-seq studies. WB:WBGene00010988 metr-1 Predicted to enable methionine synthase activity. Predicted to be involved in homocysteine metabolic process; methionine biosynthetic process; and tetrahydrofolate metabolic process. Predicted to be located in cytosol. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; and hematologic cancer (multiple). Is an ortholog of human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). WB:WBGene00010989 R03D7.2 Predicted to enable 5'-3' DNA helicase activity. Predicted to be involved in DNA duplex unwinding. WB:WBGene00010990 tceb-3 Involved in transcription elongation by RNA polymerase II. Part of transcription elongation factor complex. Is an ortholog of human ELOA2 (elongin A2) and ELOA3DP (elongin A3 family member D, pseudogene). WB:WBGene00010991 gskl-1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway and signal transduction. Predicted to be located in axon; cytosol; and nucleus. Expressed in gonad; sperm; and spermatocyte. WB:WBGene00010992 R03D7.8 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00010993 vha-20 Predicted to enable signaling receptor activity. Involved in nematode larval development and regulation of intracellular pH. Located in apical plasma membrane. Expressed in amphid neurons. Human ortholog(s) of this gene implicated in X-linked parkinsonism-spasticity syndrome; congenital disorder of glycosylation type II; and syndromic X-linked intellectual disability Hedera type. Is an ortholog of human ATP6AP2 (ATPase H+ transporting accessory protein 2). WB:WBGene00010994 lgc-25 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00010995 ceh-90 Predicted to enable DNA binding activity. Predicted to be located in nucleus. Expressed in head muscle; intestine; neurons; and somatic nervous system. WB:WBGene00010996 R03G8.1 Predicted to be located in membrane. WB:WBGene00010997 R03G8.2 No description available WB:WBGene00010998 R03G8.3 Predicted to be located in membrane. WB:WBGene00010999 R03G8.4 Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by six chemicals including methylmercury hydroxide; silicon dioxide nanoparticle; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00011000 R03G8.6 Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be located in cytoplasm. WB:WBGene00011001 R04B5.1 Predicted to be located in membrane. WB:WBGene00011002 nhr-205 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00011003 R04B5.5 Predicted to enable L-iditol 2-dehydrogenase activity. Predicted to be involved in sorbitol catabolic process. Expressed in body wall musculature and intestine. Is an ortholog of human SORD (sorbitol dehydrogenase). WB:WBGene00011004 R04B5.6 Predicted to enable L-iditol 2-dehydrogenase activity. Predicted to be involved in sorbitol catabolic process. Expressed in head neurons and pharyngeal cell. Is an ortholog of human SORD (sorbitol dehydrogenase). WB:WBGene00011005 R04B5.7 Enriched in Z1.p; Z4.a; gon_male_dtc anterior; and gon_male_dtc posterior based on RNA-seq studies. Is affected by several genes including let-60; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00011006 ugt-47 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00011007 R04B5.10 Is affected by cdk-4 and cyd-1 based on microarray studies. Is affected by Progesterone and dafa#1 based on microarray studies. WB:WBGene00011008 R04B5.11 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00011009 cyp-14A4 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and hereditary spastic paraplegia 56. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1). WB:WBGene00011010 R04D3.2 Enriched in germ line and germline precursor cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercury hydroxide; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00011011 R04D3.3 Enriched in germ line; germline precursor cell; hypodermis; neurons; and pharyngeal muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including methylmercury hydroxide; rotenone; and Alovudine based on RNA-seq; proteomic; and microarray studies. WB:WBGene00011012 R04D3.4 Enriched in several structures, including RIH; germ line; germline precursor cell; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00011013 srxa-8 Predicted to be located in membrane. WB:WBGene00011014 hpo-30 Located in dendrite. Expressed in body wall musculature; neurons; and ventral nerve cord. WB:WBGene00011015 R04F11.2 Predicted to enable proton transmembrane transporter activity. Predicted to be involved in proton motive force-driven ATP synthesis and proton transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex. Is an ortholog of human ATP5ME (ATP synthase membrane subunit e). WB:WBGene00011016 R04F11.3 Predicted to contribute to DNA-directed DNA polymerase activity. Predicted to be involved in DNA strand elongation involved in DNA replication; DNA synthesis involved in UV-damage excision repair; and nucleotide-excision repair, DNA gap filling. Predicted to be located in nuclear lumen. Predicted to be part of delta DNA polymerase complex. WB:WBGene00011017 R04F11.5 Predicted to be involved in protein insertion into mitochondrial inner membrane. Located in endoplasmic reticulum. Is an ortholog of human TIMM29 (translocase of inner mitochondrial membrane 29). WB:WBGene00011018 R05A10.1 Enriched in cephalic sheath cell; dopaminergic neurons; and hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including nicotinic acid; Sodium Chloride; and metformin based on RNA-seq and microarray studies. WB:WBGene00011019 R05A10.2 Enriched in PLM; accessory cell; arc ant V; hypodermis; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including aldicarb; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00011020 R05A10.3 Enriched in AMshL; AMshR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00011021 R05A10.4 Predicted to be located in extracellular region. WB:WBGene00011022 R05A10.5 Is affected by several genes including daf-2; rrf-3; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00011023 R05A10.6 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00011024 R05A10.7 Predicted to be located in membrane. WB:WBGene00011025 R05A10.8 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00011026 R05D7.1 Predicted to be located in membrane. WB:WBGene00011027 R05D7.2 Enriched in XXXL; XXXR; germ line; somatic gonad precursor; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00011028 R05D7.3 Predicted to be located in membrane. Is an ortholog of human TMEM200A (transmembrane protein 200A). WB:WBGene00011029 abhd-11.2 Predicted to enable carboxylic ester hydrolase activity. Predicted to be involved in cellular lipid metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human ABHD11 (abhydrolase domain containing 11). WB:WBGene00011030 nsph-1.2 Enriched in several structures, including Caaaaa; Caaaap; anterior hypodermis; germ line; and mc1 based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including pgl-1; lin-35; and lin-15B based on microarray and RNA-seq studies. Is affected by four chemicals including rotenone; Rifampin; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cytosolic motility protein. WB:WBGene00011032 ddx-52 Predicted to enable RNA helicase activity. Predicted to be involved in maturation of SSU-rRNA. Expressed widely. Is an ortholog of human DDX52 (DExD-box helicase 52). WB:WBGene00011033 tmem-208 Predicted to be involved in vacuolar protein processing. Predicted to be located in endoplasmic reticulum membrane and vacuole. Is an ortholog of human TMEM208 (transmembrane protein 208). WB:WBGene00011034 paxt-1 Predicted to be involved in mRNA processing. Located in nucleolus and nucleoplasm. Is an ortholog of human CDKN2AIPNL (CDKN2A interacting protein N-terminal like). WB:WBGene00011035 snrp-27 Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human SNRNP27 (small nuclear ribonucleoprotein U4/U6.U5 subunit 27). WB:WBGene00011036 edc-3 Predicted to enable mRNA binding activity. Predicted to be involved in P-body assembly and deadenylation-independent decapping of nuclear-transcribed mRNA. Predicted to be located in P-body. Expressed in hypodermal cell; intestinal cell; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 50. Is an ortholog of human EDC3 (enhancer of mRNA decapping 3). WB:WBGene00011037 R05D11.9 Predicted to enable sphingomyelin phosphodiesterase D activity. Predicted to be involved in ceramide biosynthetic process; glycerophospholipid catabolic process; and sphingomyelin catabolic process. Predicted to be located in endoplasmic reticulum and trans-Golgi network. Is an ortholog of human SMPD4 (sphingomyelin phosphodiesterase 4). WB:WBGene00011038 R05H5.3 Expressed in germ line. Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Thioredoxin-like superfamily; Thioredoxin-like; and Phosphorylation site. Is an ortholog of human NXNL2 (nucleoredoxin like 2). WB:WBGene00011039 R05H5.4 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00011040 arv-1 Predicted to be involved in intracellular sterol transport; lipid metabolic process; and regulation of plasma membrane sterol distribution. Predicted to be located in Golgi apparatus and cortical endoplasmic reticulum. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 38. Is an ortholog of human ARV1 (ARV1 homolog, fatty acid homeostasis modulator). WB:WBGene00011041 R05H5.7 Enriched in ABalppappa; ABarappppa; corpus; neurons; and posterior arcade cell based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by dafa#1 and adsorbable organic bromine compound based on microarray studies. WB:WBGene00011042 R05H10.1 Predicted to enable N-acetyltransferase activity. WB:WBGene00011043 rbm-28 Predicted to enable RNA binding activity. Predicted to be located in nucleolus. Expressed in head and tail. Used to study alopecia, neurologic defects, and endocrinopathy syndrome. Human ortholog(s) of this gene implicated in alopecia, neurologic defects, and endocrinopathy syndrome. Is an ortholog of human RBM28 (RNA binding motif protein 28). WB:WBGene00011044 R05H10.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00011045 gpx-2 Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple) and spondylometaphyseal dysplasia Sedaghatian type. Is an ortholog of human GPX4 (glutathione peroxidase 4). WB:WBGene00011046 R05H10.7 Predicted to enable N-acetyltransferase activity. WB:WBGene00011047 tebp-1 Predicted to enable DNA binding activity. WB:WBGene00011048 R06A4.3 No description available WB:WBGene00011049 sdz-26 Expressed in E; Ea; and Ep. Is predicted to encode a protein with the following domain: Pes-10. WB:WBGene00011050 agl-1 Predicted to enable 4-alpha-glucanotransferase activity and amylo-alpha-1,6-glucosidase activity. Predicted to be involved in glycogen catabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease III. Is an ortholog of human AGL (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase). WB:WBGene00011051 pfs-2 Predicted to be involved in mRNA polyadenylation. Located in nuclear speck. Is an ortholog of human WDR33 (WD repeat domain 33). WB:WBGene00011052 arrd-11 Predicted to enable molecular adaptor activity. Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC2 (arrestin domain containing 2). WB:WBGene00011053 arrd-12 Enriched in amphid sheath cell; body wall muscle cell; intestine; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; clk-1; and hsp-6 based on microarray; tiling array; and RNA-seq studies. Is affected by multi-walled carbon nanotube; Doxycycline; and paraquat based on RNA-seq studies. Is predicted to encode a protein with the following domains: Immunoglobulin E-set; Arrestin-like, N-terminal; Arrestin-like, C-terminal; and Arrestin (or S-antigen), N-terminal domain. WB:WBGene00011054 arrd-13 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC2 (arrestin domain containing 2). WB:WBGene00011055 arrd-14 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. WB:WBGene00011056 R06B9.5 Enriched in NSM and germ line based on RNA-seq and tiling array studies. Is affected by several genes including daf-16; daf-2; and npr-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011058 fdps-1 Predicted to enable dimethylallyltranstransferase activity and geranyltranstransferase activity. Predicted to be involved in farnesyl diphosphate biosynthetic process. Predicted to be located in cytoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in porokeratosis. Is an ortholog of human FDPS (farnesyl diphosphate synthase). WB:WBGene00011059 R06C1.4 Predicted to enable RNA binding activity. WB:WBGene00011060 R06C1.6 Enriched in muscle cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Zidovudine; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011061 wago-1 Enables DEAD/H-box RNA helicase binding activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, endonucleolytic and regulatory ncRNA-mediated gene silencing. Located in P granule. Expressed in germ line. WB:WBGene00011062 R06C7.2 Predicted to enable SUMO transferase activity. Predicted to be involved in homologous chromosome pairing at meiosis and protein sumoylation. Predicted to be located in synaptonemal complex. WB:WBGene00011063 cpg-3 Expressed in germ line. Is predicted to encode a protein with the following domain: Chondroitin proteoglycan 3. WB:WBGene00011064 adsl-1 Predicted to enable (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity and N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity. Predicted to be involved in 'de novo' AMP biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in adenylosuccinase lyase deficiency; breast cancer; and prostate cancer. Is an ortholog of human ADSL (adenylosuccinate lyase). WB:WBGene00011065 R06C7.6 Predicted to enable protein-N-terminal glutamine amidohydrolase activity. Predicted to be located in cytosol and nucleus. Is an ortholog of human NTAQ1 (N-terminal glutamine amidase 1). WB:WBGene00011066 ztf-15 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human ZNF160 (zinc finger protein 160). WB:WBGene00011067 vps-11 Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in organelle organization and vesicle docking involved in exocytosis. Predicted to be located in endosome. Predicted to be part of HOPS complex. Expressed in gonad. Human ortholog(s) of this gene implicated in dystonia and hypomyelinating leukodystrophy 12. Is an ortholog of human VPS11 (VPS11 core subunit of CORVET and HOPS complexes). WB:WBGene00011068 set-14 Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Expressed in hypodermis; intestine; and neurons. Is an ortholog of human SMYD1 (SET and MYND domain containing 1) and SMYD2 (SET and MYND domain containing 2). WB:WBGene00011069 ceh-62 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in dorsal nerve cord; neurons; tail neurons; and ventral nerve cord. WB:WBGene00011070 msrp-7 Enriched in several structures, including MSaaaaapa; MSaapaapa; MSpapaapa; g1; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including aldicarb; rotenone; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00011071 R06F6.8 Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in intracellular protein transport; negative regulation of protein catabolic process; and retrograde transport, endosome to Golgi. Predicted to be located in Golgi membrane; cytosol; and protein-containing complex. Predicted to be part of Ric1-Rgp1 guanyl-nucleotide exchange factor complex. Is an ortholog of human RIC1 (RIC1 homolog, RAB6A GEF complex partner 1). WB:WBGene00011072 tag-209 Enriched in AMshL; AMshR; amphid sheath cell; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including D-glucose; bisphenol A; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00011073 R07A4.2 Predicted to be located in membrane. WB:WBGene00011074 R07A4.3 Enriched in PVM; hypodermis; intestine; and seam cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00011075 R07A4.4 Enriched in amphid sheath cell; excretory system; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by nine chemicals including stavudine; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00011076 scav-5 Predicted to enable scavenger receptor activity. Predicted to be involved in endocytosis. Predicted to be located in cytoplasm. Is an ortholog of human SCARB1 (scavenger receptor class B member 1). WB:WBGene00011077 R07B1.5 Enriched in several structures, including ABarpapaaa; RIA; arc ant V; hyp3; and socket cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including methylmercury hydroxide; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00011078 R07B1.6 Enriched in several structures, including ABarpapaaa; arc ant V; hyp3; neurons; and socket cell based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including tryptophan; methylmercury hydroxide; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00011079 R07B1.7 Enriched in OLL; PVD; and coelomocyte based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00011081 R07B1.9 Expressed in pharynx. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011082 R07B1.11 Predicted to be located in membrane. WB:WBGene00011083 glo-1 Predicted to enable GTPase activity. Involved in lipid storage and lysosome organization. Located in gut granule membrane. Expressed in intestine. Is an ortholog of human RAB32 (RAB32, member RAS oncogene family). WB:WBGene00011084 srsx-21 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00011087 R07B7.2 Enriched in several structures, including ASG; AVG; RIM; command interneuron; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including manganese chloride; bisphenol S; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00011088 kmo-2 Predicted to enable kynurenine 3-monooxygenase activity. Predicted to be involved in kynurenine metabolic process. Predicted to be located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human KMO (kynurenine 3-monooxygenase). WB:WBGene00011089 kmo-1 Predicted to enable kynurenine 3-monooxygenase activity. Predicted to be involved in NAD metabolic process and kynurenine metabolic process. Predicted to be located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human KMO (kynurenine 3-monooxygenase). WB:WBGene00011090 R07B7.6 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00011092 R07B7.8 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Predicted to be located in membrane. Is an ortholog of human PLB1 (phospholipase B1). WB:WBGene00011093 R07B7.9 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Predicted to be located in membrane. Is an ortholog of human PLB1 (phospholipase B1). WB:WBGene00011094 R07B7.10 Predicted to enable high-affinity L-arginine transmembrane transporter activity. Predicted to be involved in mitochondrial L-ornithine transmembrane transport. Predicted to be located in mitochondrion. Is an ortholog of human SLC25A45 (solute carrier family 25 member 45); SLC25A47 (solute carrier family 25 member 47); and SLC25A48 (solute carrier family 25 member 48). WB:WBGene00011095 gana-1 Predicted to enable alpha-galactosidase activity. Involved in glycoside catabolic process. Located in cytoplasm. Expressed in coelomocyte. Used to study Fabry disease. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Schindler disease (multiple); and angiokeratoma. Is an ortholog of human GLA (galactosidase alpha) and NAGA (alpha-N-acetylgalactosaminidase). WB:WBGene00011096 R07B7.12 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00011097 nhr-206 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in response to starvation. Predicted to be located in nucleus. Expressed in several structures, including anal sphincter muscle; hyp12; rectal gland cell; tail hypodermis; and vulva. WB:WBGene00011098 nhr-207 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in response to starvation. Predicted to be located in nucleus. Expressed in several structures, including anal sphincter muscle; gonad; pharyngeal neurons; pharyngeal-intestinal valve; and rectal valve cell. WB:WBGene00011099 nhr-208 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in response to starvation. Predicted to be located in nucleus. Expressed in several structures, including anal sphincter muscle; hyp12; pharynx; rectum; and tail hypodermis. WB:WBGene00011100 nhr-209 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00011101 R07D5.2 Predicted to be located in membrane. WB:WBGene00011102 R07E3.1 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSW (cathepsin W). WB:WBGene00011103 idpa-3 Enriched in AFD; MI neuron; intestine; neurons; and pharynx based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twelve chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011104 cut-5 Predicted to be a structural constituent of cuticle. Predicted to be located in plasma membrane. Expressed in seam cell. WB:WBGene00011105 R07E3.4 Predicted to enable ATP:ADP antiporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human SLC25A31 (solute carrier family 25 member 31). WB:WBGene00011106 acl-5 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Located in endoplasmic reticulum. Expressed in head. Is an ortholog of human GPAT3 (glycerol-3-phosphate acyltransferase 3) and GPAT4 (glycerol-3-phosphate acyltransferase 4). WB:WBGene00011107 R07E3.6 Enriched in AFD; hypodermis; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-five chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00011108 R07E3.7 Predicted to be located in membrane. WB:WBGene00011109 gpch-1 Predicted to enable RNA binding activity. Predicted to be involved in mRNA processing. Predicted to be located in nucleus. Is an ortholog of human GPATCH1 (G-patch domain containing 1). WB:WBGene00011110 prdx-3 Predicted to enable thioredoxin peroxidase activity. Predicted to be involved in cell redox homeostasis; hydrogen peroxide catabolic process; and response to oxidative stress. Predicted to be located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 32. Is an ortholog of human PRDX3 (peroxiredoxin 3). WB:WBGene00011111 snfc-5 Predicted to enable transcription coactivator activity. Predicted to be involved in chromatin remodeling and positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of brahma complex; nBAF complex; and npBAF complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); central nervous system cancer (multiple); and connective tissue cancer (multiple). Is an ortholog of human SMARCB1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1). WB:WBGene00011112 R07E5.4 Predicted to enable oxidoreductase activity. WB:WBGene00011113 R07E5.5 Enriched in AVA; Z1.p; Z4.a; male distal tip cell; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including sodium arsenite; multi-walled carbon nanotube; and bisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2 superfamily. WB:WBGene00011114 R07E5.6 Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. WB:WBGene00011115 R07E5.7 Involved in IRE1-mediated unfolded protein response. Located in plasma membrane. Expressed in neurons. WB:WBGene00011116 pdcd-2 Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in X-linked myopathy with excessive autophagy. Is an ortholog of human VMA21 (vacuolar ATPase assembly factor VMA21). WB:WBGene00011117 R07E5.11 Enriched in several structures, including ABplpppaaa; excretory cell; germ line; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Rifampin; allantoin; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00011119 mpc-1 Predicted to enable pyruvate transmembrane transporter activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial pyruvate carrier deficiency. Is an ortholog of human MPC1 (mitochondrial pyruvate carrier 1). WB:WBGene00011120 R07E5.15 Enriched in germ line; somatic gonad precursor; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00011121 R07E5.17 Predicted to be located in membrane. WB:WBGene00011122 cpt-2 Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in brain disease; lipid metabolism disorder; and muscular disease. Is an ortholog of human CPT2 (carnitine palmitoyltransferase 2). WB:WBGene00011123 nuaf-3 Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 18. Is an ortholog of human NDUFAF3 (NADH:ubiquinone oxidoreductase complex assembly factor 3). WB:WBGene00011124 sdz-27 Involved in gastrulation. Predicted to be located in membrane. WB:WBGene00011125 R07H5.5 No description available WB:WBGene00011126 R07H5.6 No description available WB:WBGene00011127 fbxb-79 Is affected by several genes including eat-2; rrf-1; and mex-3 based on RNA-seq and microarray studies. Is affected by Rifampin and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00011128 adk-1 Predicted to enable adenosine kinase activity. Predicted to be involved in purine nucleobase metabolic process. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in hypermethioninemia due to adenosine kinase deficiency and temporal lobe epilepsy. Is an ortholog of human ADK (adenosine kinase). WB:WBGene00011129 R07H5.9 Enriched in PLM; germ line; intestine; sensory neurons; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; mianserin; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00011130 zip-6 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00011131 R07H5.11 Enriched in AVE; Y cell; germ line; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by four chemicals including stavudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00011132 R08A2.1 Enriched in AFD; NSM; arcade cell; germ line; and pharyngeal-intestinal valve cell based on RNA-seq and tiling array studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: DUF236 repeat. WB:WBGene00011133 R08A2.2 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00011134 ssp-33 Enriched in amphid sheath cell; germ line; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including Ethanol; D-glucose; and Alovudine based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00011135 fbxa-147 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including aak-2; hsp-6; and bar-1 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00011136 R08A2.5 Enriched in CEP socket cell; arc ant V; and neuronal sheath cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including Tunicamycin; Zidovudine; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00011137 R08A2.7 Enriched in neurons and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; alg-1; and atfs-1 based on tiling array; microarray; and RNA-seq studies. Is affected by antimycin and cholesterol based on RNA-seq studies. WB:WBGene00011139 R08B4.3 Predicted to enable metal ion binding activity. WB:WBGene00011140 R08B4.4 Predicted to be located in membrane. WB:WBGene00011141 nlp-66 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00011142 bud-13 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of RES complex and U2-type spliceosomal complex. Is an ortholog of human BUD13 (BUD13 homolog). WB:WBGene00011143 rpap-2 Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human RPAP2 (RNA polymerase II associated protein 2). WB:WBGene00011144 R08D7.4 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of human EEF2KMT (eukaryotic elongation factor 2 lysine methyltransferase) and FAM86B2 (family with sequence similarity 86 member B2). WB:WBGene00011145 R08D7.5 Predicted to enable calcium ion binding activity. Predicted to be involved in centriole replication and mitotic cell cycle. Predicted to be located in centriole and centrosome. Is an ortholog of human CETN2 (centrin 2). WB:WBGene00011146 pde-2 Predicted to enable 3',5'-cyclic-nucleotide phosphodiesterase activity and protein homodimerization activity. Involved in several processes, including determination of adult lifespan; positive regulation of egg-laying behavior; and regulation of cGMP-mediated signaling. Predicted to be located in several cellular components, including mitochondrion; perinuclear region of cytoplasm; and synaptic membrane. Expressed in AFDL and AFDR. Is an ortholog of human PDE2A (phosphodiesterase 2A). WB:WBGene00011147 R08D7.7 Predicted to enable xylulokinase activity. Predicted to be involved in phosphorylation and xylulose metabolic process. Predicted to be located in cytosol. Is an ortholog of human XYLB (xylulokinase). WB:WBGene00011149 R08H2.8 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by several genes including sir-2.1; clk-1; and npr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube; resveratrol; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00011150 nhr-269 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00011151 R08H2.10 Is affected by several genes including eat-2; sir-2.1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by Atrazine; cadmium; and fluoranthene based on microarray studies. WB:WBGene00011152 R09A8.1 Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in chromatin remodeling and regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of chromatin. WB:WBGene00011153 R09A8.2 Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in chromatin remodeling and regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of chromatin. WB:WBGene00011154 R09A8.5 Predicted to be located in membrane. Expressed in alimentary muscle; body wall musculature; rectal valve cell; and tail hypodermis. WB:WBGene00011155 rbm-3.1 Predicted to enable RNA binding activity. WB:WBGene00011156 rbm-3.2 Predicted to enable RNA binding activity. WB:WBGene00011157 chil-15 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011158 chil-16 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011159 chil-17 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011160 R09D1.4 Is affected by several genes including alg-1; atfs-1; and dpy-21 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00011161 chil-18 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011162 chil-19 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011163 chil-20 Enriched in NSM; SMBDL; SMBDR; SMBVL; and SMBVR based on tiling array and single-cell RNA-seq studies. Is affected by several genes including age-1; let-60; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Tunicamycin; paraquat; and cadmium based on microarray and RNA-seq studies. WB:WBGene00011164 chil-21 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011165 R09D1.9 Enriched in intestine based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and unc-30 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Rifampin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00011166 chil-22 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011167 chil-23 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011168 R09D1.12 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); central nervous system cancer (multiple); and hematologic cancer (multiple). Is an ortholog of human FLT3 (fms related receptor tyrosine kinase 3); PDGFRA (platelet derived growth factor receptor alpha); and PDGFRB (platelet derived growth factor receptor beta). WB:WBGene00011169 R09D1.13 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); and prostate cancer. Is an ortholog of human FLT3 (fms related receptor tyrosine kinase 3). WB:WBGene00011170 R09D1.14 Predicted to be involved in carbohydrate metabolic process. WB:WBGene00011171 R09E10.1 Enriched in AVK; germ line; neurons; sensory neurons; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00011172 R09E10.2 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00011173 acs-18 Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in acute myeloid leukemia and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1) and ACSL6 (acyl-CoA synthetase long chain family member 6). WB:WBGene00011174 acs-23 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; RNA-seq; and tiling array studies. Is affected by five chemicals including multi-walled carbon nanotube; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00011175 R09E10.5 Predicted to be involved in cell-matrix adhesion. Predicted to be located in extracellular space. WB:WBGene00011176 R09E10.6 Enriched in several structures, including AVK; germ line; hypodermis; sperm; and touch receptor neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-three chemicals including Ethanol; 1-methylnicotinamide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00011177 R09E10.8 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; pmk-1; and tph-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Alovudine; stavudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00011178 R09E10.9 Enriched in NSM; germ line; and in male based on RNA-seq and tiling array studies. Is affected by several genes including pmk-1; isp-1; and hsp-6 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00011179 R09H10.1 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00011180 R09H10.2 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00011181 R09H10.3 Enables identical protein binding activity. Predicted to be involved in purine nucleobase metabolic process. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; colorectal adenoma; dystransthyretinemic hyperthyroxinemia; and gastrointestinal system cancer (multiple). Is an ortholog of human TTR (transthyretin). WB:WBGene00011182 R09H10.5 Enriched in ALM; BDU; coelomocyte; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MD domain and EGF-like domain. WB:WBGene00011183 R09H10.6 Predicted to enable calcium ion binding activity. WB:WBGene00011184 R09H10.7 Predicted to be located in membrane. WB:WBGene00011185 R10D12.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00011186 clec-226 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; and PAN-3 domain. WB:WBGene00011187 R10D12.6 Predicted to be located in membrane. WB:WBGene00011188 R10D12.7 Predicted to be located in membrane. WB:WBGene00011189 R10D12.8 Enriched in germ line; intestine; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including D-glucose; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00011190 swt-6 Predicted to enable sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport. Predicted to be located in Golgi membrane and plasma membrane. WB:WBGene00011191 R10D12.10 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00011192 srh-24 Predicted to be located in membrane. WB:WBGene00011193 algn-13 Predicted to enable N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 36. Is an ortholog of human ALG13 (ALG13 UDP-N-acetylglucosaminyltransferase subunit). WB:WBGene00011194 R10D12.13 Enriched in MSpaaapa; germ line; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and let-60 based on microarray and RNA-seq studies. Is affected by five chemicals including paraquat; Atrazine; and Hydrolyzable Tannins based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ccdc97-like; Coiled-coil domain containing protein 97-like, C-terminal; and CCD97-like, C-terminal. Is an ortholog of human CCDC97 (coiled-coil domain containing 97). WB:WBGene00011195 sao-1 Enables WD40-repeat domain binding activity. Involved in negative regulation of Notch signaling pathway and regulation of protein deneddylation. Located in cell cortex and cleavage furrow. WB:WBGene00011196 R10D12.15 Predicted to enable chitinase activity. Predicted to be involved in cell wall macromolecule catabolic process and chitin catabolic process. WB:WBGene00011197 srw-145 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in accessory cell; phasmid neurons; and sensory neurons. WB:WBGene00011198 R10E4.1 Enriched in excretory cell; germ line; intestine; and neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00011200 R10E4.3 Predicted to be located in membrane. WB:WBGene00011201 nth-1 Enables 5-formyluracil DNA N-glycosylase activity and 5-hydroxymethyluracil DNA N-glycosylase activity. Involved in cellular response to hydrogen peroxide and depyrimidination. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in familial adenomatous polyposis 3. Is an ortholog of human NTHL1 (nth like DNA glycosylase 1). WB:WBGene00011202 R10E4.6 Predicted to be located in membrane. WB:WBGene00011203 R10E4.7 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-eight chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00011204 R10E4.8 No description available WB:WBGene00011205 R10E4.9 Predicted to enable 3-hydroxyacyl-CoA dehydratase activity. Predicted to be involved in fatty acid elongation; sphingolipid biosynthetic process; and very long-chain fatty acid biosynthetic process. Located in plasma membrane. Is an ortholog of human HACD3 (3-hydroxyacyl-CoA dehydratase 3). WB:WBGene00011206 R10E4.11 Predicted to enable chromatin insulator sequence binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome. WB:WBGene00011207 R10E8.1 Enriched in intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; Zidovudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00011208 R10E8.2 Is affected by several genes including npr-1; drh-3; and mrps-5 based on tiling array; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00011209 R10E8.3 Enriched in OLL; PVD; and intestine based on microarray and tiling array studies. Is affected by several genes including skn-1; elt-2; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box domain. WB:WBGene00011210 R10E8.4 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride; multi-walled carbon nanotube; and allantoin based on microarray and RNA-seq studies. WB:WBGene00011211 R10E8.5 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00011212 R10E8.6 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including stavudine; Zidovudine; and Cadmium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00011213 R10E8.8 Enriched in head mesodermal cell and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily and F-box domain. WB:WBGene00011214 R10E9.2 Enriched in several structures, including GABAergic neurons; RIM; germ line; interneuron; and sperm based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-seven chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00011215 R10E9.3 Predicted to be located in membrane. WB:WBGene00011216 usp-46 Enables cysteine-type deubiquitinase activity and ionotropic glutamate receptor binding activity. Involved in anterior/posterior axis specification, embryo; positive regulation of gene expression; and positive regulation of locomotion involved in locomotory behavior. Located in endosome and neuronal cell body. Expressed in body wall musculature; intestine; nervous system; pharynx; and vulval muscle. Is an ortholog of human USP46 (ubiquitin specific peptidase 46). WB:WBGene00011217 R10E11.5 Enriched in head mesodermal cell and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00011218 R10E11.6 Enriched in AVK; NSM; anterior hypodermis; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and gld-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Rifampin; allantoin; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Synergin gamma and EF-hand domain pair. Is an ortholog of human SYNRG (synergin gamma). WB:WBGene00011219 srxa-10 Predicted to be located in membrane. WB:WBGene00011220 R10E11.9 Predicted to be located in membrane. WB:WBGene00011221 R10E12.2 Enriched in several structures, including ABplpaaaap; germ line; head mesodermal cell; neurons; and pm7 based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Zidovudine; Rifampin; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Uncharacterized protein C05B5.4-like. WB:WBGene00011222 R10H10.3 Enriched in head mesodermal cell; intestine; pharyngeal muscle cell; and sensory neurons based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by eighteen chemicals including Mercuric Chloride; D-glucose; and bisphenol A based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; Uncharacterised conserved protein UCP027682, CUB, vWA; Spermadhesin, CUB domain superfamily; von Willebrand factor A-like domain superfamily; and CUB domain. WB:WBGene00011223 R10H10.4 Predicted to be located in membrane. Expressed in AIYL and AIYR. WB:WBGene00011224 rfk-1 Predicted to enable riboflavin kinase activity. Predicted to be involved in FMN biosynthetic process and riboflavin metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human RFK (riboflavin kinase). WB:WBGene00011225 R10H10.7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in cytoplasm. Predicted to be part of ASTRA complex. Is an ortholog of human TTI1 (TELO2 interacting protein 1). WB:WBGene00011226 slc-25A21 Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 18. Is an ortholog of human SLC25A21 (solute carrier family 25 member 21). WB:WBGene00011227 nlp-67 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00011228 R11.3 Predicted to be located in motile cilium. WB:WBGene00011229 R11.4 Predicted to be located in membrane. WB:WBGene00011230 nud-2 Predicted to enable microtubule binding activity. Involved in GABAergic synaptic transmission; nuclear migration; and synaptic vesicle transport. Located in nuclear envelope. Expressed in several structures, including germ cell; hypodermal cell; non-striated muscle; rectal valve cell; and tail hypodermis. Used to study epilepsy and lissencephaly. Human ortholog(s) of this gene implicated in lissencephaly 4 and schizophrenia. Is an ortholog of human NDE1 (nudE neurodevelopment protein 1) and NDEL1 (nudE neurodevelopment protein 1 like 1). WB:WBGene00011231 R11A5.3 Expressed in Z1 and Z4. WB:WBGene00011232 pck-2 Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Predicted to be located in cytosol and mitochondrion. Expressed in several structures, including body wall musculature; hypodermis; muscle cell; pharynx; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is an ortholog of human PCK1 (phosphoenolpyruvate carboxykinase 1). WB:WBGene00011234 R11A5.6 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including rotenone; Tunicamycin; and antimycin based on RNA-seq and microarray studies. WB:WBGene00011235 suro-1 Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Located in collagen and cuticulin-based cuticle extracellular matrix and cytoplasm. Expressed in hypodermis. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Is an ortholog of human CPA6 (carboxypeptidase A6). WB:WBGene00011236 R11A8.1 Enriched in coelomocyte; germ line; germline precursor cell; head mesodermal cell; and hyp3 based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and elt-2 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00011237 gkow-1 Predicted to enable nucleic acid binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human GPKOW (G-patch domain and KOW motifs). WB:WBGene00011238 ugt-59 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00011239 pges-2 Predicted to enable prostaglandin-E synthase activity. Predicted to be involved in prostaglandin biosynthetic process. Predicted to be located in mitochondrion. Expressed in hypodermis; intestinal cell; lumbar ganglion; muscle cell; and retrovesicular ganglion. Is an ortholog of human PTGES2 (prostaglandin E synthase 2). WB:WBGene00011240 mask-1 Predicted to enable RNA binding activity. Predicted to be located in cytoplasm. Expressed in head. Is an ortholog of human ANKHD1 (ankyrin repeat and KH domain containing 1); ANKHD1-EIF4EBP3 (ANKHD1-EIF4EBP3 readthrough); and ANKRD17 (ankyrin repeat domain 17). WB:WBGene00011241 mpz-5 Enriched in ALN; body wall muscle cell; germ line; mechanosensory neurons; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Sodium Chloride; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Uncharacterized protein T15H9.4-like. WB:WBGene00011242 R11D1.1 Predicted to be involved in negative regulation of fatty acid biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Is an ortholog of human DCAF5 (DDB1 and CUL4 associated factor 5). WB:WBGene00011243 R11D1.2 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including let-60; pgl-1; and aak-2 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00011244 R11D1.3 Expressed in amphid sheath cell. WB:WBGene00011245 R11D1.4 Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including daf-2; sir-2.1; and mir-34 based on tiling array; microarray; and RNA-seq studies. Is affected by dafa#1 and Sirolimus based on microarray studies. WB:WBGene00011246 R11D1.7 Predicted to be located in membrane. WB:WBGene00011247 mrpl-49 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL49 (mitochondrial ribosomal protein L49). WB:WBGene00011248 R11D1.10 Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in abscission and mitotic cytokinesis checkpoint signaling. Predicted to be located in centrosome; cleavage furrow; and midbody. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Is an ortholog of human ZFYVE19 (zinc finger FYVE-type containing 19). WB:WBGene00011249 semi-1 Predicted to enable selenium binding activity. Human ortholog(s) of this gene implicated in glaucoma. Is an ortholog of human SELENBP1 (selenium binding protein 1). WB:WBGene00011250 R11H6.2 Predicted to be located in membrane. Is an ortholog of human SERINC1 (serine incorporator 1) and SERINC3 (serine incorporator 3). WB:WBGene00011251 glb-22 Predicted to enable heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00011252 R11H6.4 Enriched in several structures, including germ line; gonad; neurons; rectal gland cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; manganese chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00011253 R11H6.5 Predicted to enable DNA binding activity and double-stranded RNA binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Expressed in pharyngeal neurons. Is an ortholog of human ILF2 (interleukin enhancer binding factor 2). WB:WBGene00011254 R12G8.1 Predicted to enable ATP binding activity and protein serine/threonine kinase activity. WB:WBGene00011255 R12H7.4 Predicted to be located in membrane. WB:WBGene00011257 npax-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Expressed in dorsal nerve cord; head neurons; intestine; and tail neurons. WB:WBGene00011258 best-15 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). WB:WBGene00011259 miz-1 Predicted to enable SUMO ligase activity and nuclear receptor coactivator activity. Predicted to be involved in protein sumoylation and regulation of transcription by RNA polymerase II. Expressed in several structures, including anal depressor muscle; egg-laying apparatus; nervous system; pharyngeal-intestinal valve; and pharynx. Is an ortholog of human ZMIZ2 (zinc finger MIZ-type containing 2). WB:WBGene00011260 cnnm-5 Involved in determination of adult lifespan and positive regulation of gonad development. Predicted to be located in cytoplasm. WB:WBGene00011261 nphp-4 Involved in several processes, including determination of adult lifespan; male mating behavior; and plasma membrane bounded cell projection organization. Located in ciliary basal body; ciliary transition zone; and non-motile cilium. Expressed in cloacal ganglion; neurons; and tail ganglion. Used to study Meckel syndrome and nephronophthisis. Human ortholog(s) of this gene implicated in several diseases, including Joubert syndrome 4; Senior-Loken syndrome; and nephronophthisis 4. Is an ortholog of human NPHP4 (nephrocystin 4). WB:WBGene00011262 pho-8 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J. Is an ortholog of human ACP2 (acid phosphatase 2, lysosomal) and ACP4 (acid phosphatase 4). WB:WBGene00011263 R13H4.5 Expressed in several structures, including anal depressor muscle; excretory cell; intestine; rectal muscle; and vulva. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00011264 R13H4.6 Predicted to enable ATP binding activity; ATP-dependent peptidase activity; and serine-type endopeptidase activity. Predicted to be involved in protein catabolic process and proteolysis. WB:WBGene00011265 R13H4.7 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00011266 idpb-5 Enriched in g1AL; g1AR; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including 1-methylnicotinamide; methylmercuric chloride; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011267 fbxb-85 Enriched in several structures, including ABplaapaaa; ABplapaaaap; ABplapaaapa; AVA; and NSM based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including Mercuric Chloride; rotenone; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00011268 pde-12 Predicted to enable poly(A)-specific ribonuclease activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, exonucleolytic. Is an ortholog of human PDE12 (phosphodiesterase 12). WB:WBGene00011269 sbsp-1 Expressed in intestine and rectal gland cell. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat superfamily; Somatomedin-B and thrombospondin type-1 domain-containing protein; Thrombospondin type-1 (TSP1) repeat; Somatomedin B-like domain superfamily; and Somatomedin B domain. Is an ortholog of human SBSPON (somatomedin B and thrombospondin type 1 domain containing). WB:WBGene00011270 R31.2 Located in striated muscle myosin thick filament. Is an ortholog of human ANKRD40 (ankyrin repeat domain 40). WB:WBGene00011271 flad-1 Predicted to enable FMN adenylyltransferase activity. Predicted to be involved in FAD biosynthetic process. Is an ortholog of human FLAD1 (flavin adenine dinucleotide synthetase 1). WB:WBGene00011272 dtmk-1 Predicted to enable nucleoside diphosphate kinase activity and thymidylate kinase activity. Predicted to be involved in dTDP biosynthetic process; dTTP biosynthetic process; and dUDP biosynthetic process. Predicted to be located in mitochondrion and nucleus. Is an ortholog of human DTYMK (deoxythymidylate kinase). WB:WBGene00011273 R53.4 Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Predicted to be located in mitochondrial membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex. Is an ortholog of human ATP5MF (ATP synthase membrane subunit f). WB:WBGene00011274 R53.5 Predicted to enable antioxidant activity. Predicted to be involved in cellular oxidant detoxification. Predicted to be located in cytoplasm. Expressed in hypodermis; muscle cell; and ventral nerve cord. Is an ortholog of human PRXL2A (peroxiredoxin like 2A). WB:WBGene00011275 psf-1 Predicted to be involved in DNA strand elongation involved in mitotic DNA replication. Predicted to be located in nucleus. Predicted to be part of GINS complex. Human ortholog(s) of this gene implicated in immunodeficiency 55. Is an ortholog of human GINS1 (GINS complex subunit 1). WB:WBGene00011276 aakg-5 Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleotide-activated protein kinase complex. Expressed in several structures, including epithelial cell; excretory cell; hermaphrodite gonad; neurons; and vulva. WB:WBGene00011277 R53.8 Enriched in ADF; AFD; PLM; male-specific anatomical entity; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; let-60; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00011278 R74.2 Enriched in germline precursor cell and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011279 asd-1 Enables single-stranded RNA binding activity. Predicted to be involved in nervous system development and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleus. Expressed in body wall musculature; intestine; nervous system; and vulval muscle. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; hypoplastic left heart syndrome; myotonic dystrophy type 1; and type 2 diabetes mellitus. Is an ortholog of human RBFOX1 (RNA binding fox-1 homolog 1); RBFOX2 (RNA binding fox-1 homolog 2); and RBFOX3 (RNA binding fox-1 homolog 3). WB:WBGene00011280 pelo-1 Predicted to enable metal ion binding activity. Predicted to be involved in nonfunctional rRNA decay; nuclear-transcribed mRNA catabolic process, no-go decay; and ribosome disassembly. Predicted to be located in cytoplasm. Is an ortholog of human PELO (pelota mRNA surveillance and ribosome rescue factor). WB:WBGene00011281 R74.7 Predicted to enable S-adenosyl-L-methionine binding activity; tRNA (cytidine 32-2'-O)-methyltransferase activity; and tRNA (guanosine-2'-O-)-methyltransferase activity. Predicted to be involved in cytoplasmic translation; neurogenesis; and wobble position ribose methylation. Predicted to be located in cytosol. Expressed in tail. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 9. Is an ortholog of human FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1). WB:WBGene00011282 R74.8 Enriched in M cell; germ line; germline precursor cell; neurons; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; hsf-1; and gld-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Six-bladed beta-propeller, TolB-like. WB:WBGene00011283 ttbk-7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Expressed in amphid neurons. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00011284 ttr-27 Predicted to be located in cell surface and extracellular region. WB:WBGene00011285 ttr-28 Predicted to be located in cell surface and extracellular region. WB:WBGene00011286 ttr-29 Predicted to be located in cell surface and extracellular region. WB:WBGene00011287 glb-24 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00011288 R102.1 Enriched in head mesodermal cell; muscle cell; neurons; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and prg-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4440; Domain of unknown function (DUF4440); and NTF2-like domain superfamily. WB:WBGene00011289 R102.2 Expressed in neurons. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4440; Domain of unknown function (DUF4440); and NTF2-like domain superfamily. WB:WBGene00011290 R102.3 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including eat-2; npr-1; and pgl-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00011291 R102.4 Predicted to enable L-allo-threonine aldolase activity. Predicted to be involved in glycine biosynthetic process and threonine catabolic process. Predicted to be located in cytosol. WB:WBGene00011292 allo-1 Enables protein homodimerization activity. Involved in autophagosome assembly and regulation of autophagy. Located in cytoplasm. WB:WBGene00011293 R102.6 Predicted to be located in membrane. WB:WBGene00011294 R102.7 Enriched in NSM; cephalic sheath cell; dopaminergic neurons; germ line; and hypodermis based on proteomic; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Rifampin; Psoralens; and Doxycycline based on RNA-seq studies. WB:WBGene00011295 R102.8 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and aak-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; D-glucose; and metformin based on microarray and RNA-seq studies. WB:WBGene00011296 glb-21 Predicted to enable heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Expressed in head neurons; lateral nerve cord; pharynx; ventral cord neurons; and ventral nerve cord. WB:WBGene00011297 R102.10 Enriched in ABalpapaap; ABarappaap; germ line; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including nicotinic acid; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00011298 R107.2 Predicted to enable ATP-dependent NAD(P)H-hydrate dehydratase activity. Predicted to be involved in metabolite repair. Is an ortholog of human NAXD (NAD(P)HX dehydratase). WB:WBGene00011299 ikke-1 Predicted to enable protein serine/threonine kinase activity. Involved in regulation of autophagy. Located in cytoplasm. Expressed in intestinal muscle. WB:WBGene00011300 R107.5 Enriched in several structures, including germ line; intestine; neurons; rectal epithelial cell; and rectum based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including glp-1; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including rotenone; Zidovudine; and sucrose based on RNA-seq and microarray studies. WB:WBGene00011302 R166.2 Predicted to be located in endomembrane system and membrane. Is an ortholog of human CLPTM1 (CLPTM1 regulator of GABA type A receptor forward trafficking). WB:WBGene00011303 R166.3 Enriched in several structures, including ABalaapppa; ABalapaaaa; ABalapaapa; germ line; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including gld-1; sir-2.1; and hlh-30 based on RNA-seq; microarray; and proteomic studies. Is affected by ten chemicals including rotenone; Cry5B; and Linolenic Acids based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in midface hypoplasia, hearing impairment, elliptocytosis, and nephrocalcinosis. Is predicted to encode a protein with the following domains: AMMECR1; AMMECR1 domain superfamily; AMMECR1 domain; and AMMECR1, N-terminal. Is an ortholog of human AMMECR1 (AMMECR nuclear protein 1) and AMMECR1L (AMMECR1 like). WB:WBGene00011304 mnk-1 Predicted to enable calcium-dependent protein serine/threonine kinase activity; calmodulin binding activity; and calmodulin-dependent protein kinase activity. Involved in behavioral response to nicotine; determination of adult lifespan; and regulation of protein deneddylation. Located in nucleus. Expressed in body wall musculature; intestine; pharyngeal muscle cell; pharynx; and vulval muscle. Is an ortholog of human MKNK2 (MAPK interacting serine/threonine kinase 2). WB:WBGene00011305 hrg-9 Predicted to be involved in Golgi organization and protein secretion. Predicted to be located in Golgi apparatus. Is an ortholog of human TANGO2 (transport and golgi organization 2 homolog). WB:WBGene00011306 R186.3 Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in plasma membrane. Is an ortholog of human SRPRB (SRP receptor subunit beta). WB:WBGene00011307 mpst-7 Predicted to enable thiosulfate sulfurtransferase activity. Predicted to be located in mitochondrion. Is an ortholog of human MPST (mercaptopyruvate sulfurtransferase). WB:WBGene00011308 pnn-1 Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human PNN (pinin, desmosome associated protein). WB:WBGene00011309 R186.8 Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. WB:WBGene00011310 T01B4.3 Enriched in several structures, including CAN; SIA; enteric muscle; head mesodermal cell; and hyp3 based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; elt-2; and clk-1 based on RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011311 T01B7.5 Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human UTP3 (UTP3 small subunit processome component). WB:WBGene00011312 trcs-2 Enriched in ABaraappaa; germ line; sensory neurons; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eleven chemicals including bisphenol S; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011313 idpb-4 Enriched in cholinergic neurons; intestine; mechanosensory neurons; and pharynx based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00011314 T01B7.9 Enriched in several structures, including ABalapapapa; ABalapppapa; head mesodermal cell; neurons; and pm6 based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by eleven chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011315 mbr-1 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including AUA; intestine; nerve ring neurons; tail; and vulva. Is an ortholog of human LCOR (ligand dependent nuclear receptor corepressor) and LCORL (ligand dependent nuclear receptor corepressor like). WB:WBGene00011317 T01C1.4 Enriched in neurons and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including elt-2; alg-1; and dpy-21 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Tunicamycin; multi-walled carbon nanotube; and iron oxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00011318 cdt-2 Predicted to enable protein-macromolecule adaptor activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in nucleus. Expressed in vulval cell and vulval precursor cell. Is an ortholog of human DTL (denticleless E3 ubiquitin protein ligase homolog). WB:WBGene00011319 T01C3.2 Predicted to enable transcription coactivator activity. Predicted to be involved in several processes, including nitrogen compound transport; positive regulation of DNA-templated transcription; and transcription elongation by RNA polymerase II. Located in nucleus. WB:WBGene00011320 T01C3.3 Predicted to enable metal ion binding activity. Expressed in germ line and oocyte. WB:WBGene00011321 fil-1 Enables lipase activity. Involved in lipid catabolic process. WB:WBGene00011322 irld-14 Predicted to be located in membrane. WB:WBGene00011323 mut-15 Located in mutator focus. Expressed in germ line. WB:WBGene00011324 hrde-2 Predicted to be involved in regulatory ncRNA-mediated gene silencing. Predicted to be located in nucleus. Expressed in Z2; Z3; sperm; and in male. WB:WBGene00011325 T01C3.11 Predicted to be located in membrane. WB:WBGene00011326 T01D3.1 Predicted to enable calcium ion binding activity. Predicted to be involved in motor neuron axon guidance. Predicted to be located in membrane. WB:WBGene00011327 hlh-34 Predicted to enable DNA binding activity. Involved in several processes, including neuron fate specification; pharyngeal pumping; and serotonin receptor signaling pathway. Predicted to be located in nucleus. Expressed in ABalapaaap; ABalappapp; AVJL; and AVJR. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); arthritis (multiple); and kidney cancer (multiple). Is an ortholog of several human genes including NPAS1 (neuronal PAS domain protein 1); SIM1 (SIM bHLH transcription factor 1); and SIM2 (SIM bHLH transcription factor 2). WB:WBGene00011328 T01D3.3 Predicted to enable metal ion binding activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in superoxide metabolic process. Predicted to be located in extracellular region. WB:WBGene00011329 zipt-9 Predicted to enable metal ion transmembrane transporter activity. Predicted to be involved in transmembrane transport and zinc ion transport. Predicted to be located in Golgi apparatus and membrane. Expressed in seam cell. Is an ortholog of human SLC39A9 (solute carrier family 39 member 9). WB:WBGene00011330 T01D3.6 Predicted to enable calcium ion binding activity and serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. Is an ortholog of human ZAN (zonadhesin). WB:WBGene00011331 T01E8.1 Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. WB:WBGene00011333 nrde-2 Involved in regulatory ncRNA-mediated heterochromatin formation and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in nucleus. Expressed widely. Is an ortholog of human NRDE2 (NRDE-2, necessary for RNA interference, domain containing). WB:WBGene00011334 mrps-14 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 38. Is an ortholog of human MRPS14 (mitochondrial ribosomal protein S14). WB:WBGene00011335 T01E8.8 Enriched in several structures, including VC neuron; germ line; hermaphrodite gonad; pharyngeal cell; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by nine chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011336 ubxn-5 Enriched in sperm and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; methylmercuric chloride; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: UBX domain and Ubiquitin-like domain superfamily. WB:WBGene00011337 T01G1.2 Predicted to be located in membrane. Expressed in head. WB:WBGene00011338 sec-31 Predicted to enable structural molecule activity. Predicted to be involved in COPII-coated vesicle cargo loading; endoplasmic reticulum organization; and intracellular protein transport. Predicted to be located in endoplasmic reticulum exit site. Predicted to be part of COPII vesicle coat. Is an ortholog of human SEC31A (SEC31 homolog A, COPII coat complex component). WB:WBGene00011339 flor-1 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. WB:WBGene00011340 ugt-30 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00011341 T01G5.6 Predicted to be located in membrane. WB:WBGene00011342 T01G5.7 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. WB:WBGene00011344 T01G9.2 Predicted to be involved in Golgi to plasma membrane protein transport. Located in striated muscle dense body. Is an ortholog of human PHAF1 (phagosome assembly factor 1). WB:WBGene00011345 dma-1 Enables protease binding activity. Involved in neuron development and regulation of cell morphogenesis. Located in dendrite membrane. Expressed in head neurons; sensory neurons; somatic nervous system; and vulva. WB:WBGene00011346 C06B8.t3 Is affected by daf-2 based on microarray studies. WB:WBGene00011348 T01H3.2 Predicted to be located in membrane. Is an ortholog of human TECPR1 (tectonin beta-propeller repeat containing 1). WB:WBGene00011349 T01H3.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in body wall musculature; nerve ring; pharynx; spermatheca; and vulval muscle. WB:WBGene00011350 perm-1 Predicted to be located in membrane. WB:WBGene00011351 T01H3.5 Enriched in AVK; excretory cell; intestine; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on RNA-seq studies. Is affected by five chemicals including Tunicamycin; Cry5B; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00011352 rskn-1 Predicted to enable ribosomal protein S6 kinase activity. Predicted to be involved in intracellular signal transduction and phosphorylation. Predicted to be located in cytoplasm and nucleoplasm. Human ortholog(s) of this gene implicated in Coffin-Lowry syndrome and non-syndromic X-linked intellectual disability 19. Is an ortholog of several human genes including RPS6KA1 (ribosomal protein S6 kinase A1); RPS6KA2 (ribosomal protein S6 kinase A2); and RPS6KA3 (ribosomal protein S6 kinase A3). WB:WBGene00011353 serr-1 Predicted to enable L-serine ammonia-lyase activity; amino-acid racemase activity; and ion binding activity. Predicted to be involved in D-serine biosynthetic process. Is an ortholog of human SRR (serine racemase). WB:WBGene00011354 lgc-13 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Is an ortholog of human HTR3E (5-hydroxytryptamine receptor 3E). WB:WBGene00011355 lgc-14 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00011356 lgc-15 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00011357 T01H10.4 Is affected by several genes including wdr-5.1; mrps-5; and hmg-3 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; paraquat; and resveratrol based on microarray and RNA-seq studies. WB:WBGene00011358 lgc-16 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00011359 lgc-17 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00011360 lgc-18 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00011361 lyst-1 Predicted to enable protein kinase binding activity. Predicted to be involved in protein localization. Predicted to be located in cytosol and membrane. Expressed in neurons and pharyngeal cell. WB:WBGene00011362 cest-1.1 Predicted to enable carboxylic ester hydrolase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). WB:WBGene00011363 ocam-1 Enriched in M cell; Z1.p; Z4.a; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; elt-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by Rifampin; allantoin; and Colistin based on RNA-seq and microarray studies. WB:WBGene00011364 cest-1.2 Predicted to enable carboxylic ester hydrolase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). WB:WBGene00011365 T02C1.1 Predicted to enable metal ion binding activity. Is an ortholog of human LONRF3 (LON peptidase N-terminal domain and ring finger 3). WB:WBGene00011366 T02C1.2 Predicted to enable nucleosome binding activity and ubiquitin-protein transferase activity. Predicted to be involved in double-strand break repair. Predicted to be located in nucleus and site of double-strand break. Is an ortholog of human RNF169 (ring finger protein 169). WB:WBGene00011367 snpc-3.4 Predicted to enable RNA polymerase III type 3 promoter sequence-specific DNA binding activity and bent DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and core promoter sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of snRNA-activating protein complex. Is an ortholog of human SNAPC3 (small nuclear RNA activating complex polypeptide 3). WB:WBGene00011368 tftc-5 Predicted to enable DNA binding activity. Predicted to contribute to RNA polymerase III type 1 promoter sequence-specific DNA binding activity and RNA polymerase III type 2 promoter sequence-specific DNA binding activity. Predicted to be involved in transcription initiation at RNA polymerase III promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIIC complex. Is an ortholog of human GTF3C5 (general transcription factor IIIC subunit 5). WB:WBGene00011369 T02C12.4 Enriched in germline precursor cell and in male based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Sodium Chloride; and metformin based on microarray and RNA-seq studies. WB:WBGene00011370 T02D1.1 No description available WB:WBGene00011371 T02D1.4 Predicted to be located in membrane. WB:WBGene00011372 npr-26 Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection. WB:WBGene00011373 T02D1.7 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array and RNA-seq studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011374 T02D1.8 Enriched in carbon dioxide sensory neurons; head mesodermal cell; intestine; and muscle cell based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq; microarray; and proteomic studies. Is affected by twelve chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4440; Domain of unknown function (DUF4440); and NTF2-like domain superfamily. WB:WBGene00011375 T02E1.2 Enriched in RMED and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including D-glucose; Zidovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Regulator protein PHA-1 and Regulator protein, PHA-1. WB:WBGene00011376 gla-3 Predicted to enable metal ion binding activity. Located in cell cortex. Expressed in germ line; muscle cell; and somatic cell. WB:WBGene00011378 T02E1.6 Predicted to be located in membrane. WB:WBGene00011379 T02E1.7 Predicted to be involved in Golgi organization. Predicted to be located in endoplasmic reticulum and endoplasmic reticulum-Golgi intermediate compartment. WB:WBGene00011380 T02E1.8 Predicted to be located in membrane. WB:WBGene00011381 npr-25 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of human MCHR2 (melanin concentrating hormone receptor 2). WB:WBGene00011382 dop-5 Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to be located in dendrite. Expressed in neurons. WB:WBGene00011383 T02E9.5 Enriched in several structures, including ABalaapppa; cephalic sheath cell; head mesodermal cell; neurons; and pharyngeal cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq; microarray; and proteomic studies. WB:WBGene00011386 T02G6.3 Is affected by several genes including eat-2; pgl-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00011387 T02G6.4 Predicted to be located in membrane. WB:WBGene00011388 T02G6.5 Predicted to be located in membrane. WB:WBGene00011389 T02G6.6 Enriched in NSM based on tiling array studies. Is affected by several genes including eat-2; clk-1; and mex-3 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including indole; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00011390 T02G6.7 Is affected by several genes including clk-1; hpl-2; and set-2 based on tiling array; microarray; and RNA-seq studies. Is affected by Chlorpyrifos; Diazinon; and copper sulfate based on microarray studies. WB:WBGene00011391 mrps-12 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS12 (mitochondrial ribosomal protein S12). WB:WBGene00011392 sbt-1 Enables peptidase activator activity and peptidase inhibitor activity. Involved in regulation of muscle contraction. Predicted to be located in extracellular region and secretory granule. Expressed in neurons and pharynx. Is an ortholog of human SCG5 (secretogranin V). WB:WBGene00011393 T03D8.6 Predicted to enable glutathione hydrolase activity. Predicted to be involved in glutathione catabolic process. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including biliary atresia; diabetes mellitus (multiple); and liver disease (multiple). Is an ortholog of human GGT1 (gamma-glutamyltransferase 1); GGT2P (gamma-glutamyltransferase 2, pseudogene); and GGT3P (gamma-glutamyltransferase 3 pseudogene). WB:WBGene00011394 T03D8.7 Enriched in neurons based on tiling array; microarray; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00011395 T03E6.2 Is affected by several genes including daf-16; clk-1; and mir-34 based on microarray and tiling array studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00011396 nhr-271 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in amphid neurons and rectal gland cell. WB:WBGene00011397 T03E6.8 Predicted to be located in membrane. WB:WBGene00011398 qdpr-1 Predicted to enable 6,7-dihydropteridine reductase activity; NADH binding activity; and NADPH binding activity. Predicted to be involved in L-phenylalanine catabolic process and tetrahydrobiopterin biosynthetic process. Predicted to be located in cytoplasm. Expressed in several structures, including CEP; gonad; hypodermis; serotonergic neurons; and tail. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia C and phenylketonuria. Is an ortholog of human QDPR (quinoid dihydropteridine reductase). WB:WBGene00011399 T03F6.3 Predicted to enable glucosamine-6-phosphate deaminase activity and identical protein binding activity. Predicted to be involved in N-acetylglucosamine catabolic process; N-acetylneuraminate catabolic process; and glucosamine catabolic process. Predicted to be located in cytoplasm. Expressed in tail. Is an ortholog of human GNPDA1 (glucosamine-6-phosphate deaminase 1). WB:WBGene00011400 T03F6.4 Enriched in anterior hypodermis; dopaminergic neurons; mechanosensory neurons; and rectal epithelial cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including rotenone; D-glucose; and Neurotoxins based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: F-box-like domain superfamily. WB:WBGene00011401 T03F6.6 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 77. Is an ortholog of human REEP5 (receptor accessory protein 5) and REEP6 (receptor accessory protein 6). WB:WBGene00011402 T03F7.5 Predicted to be located in membrane. WB:WBGene00011403 T03F7.6 Predicted to be located in membrane. WB:WBGene00011404 T03F7.7 Predicted to be located in cytoplasm. WB:WBGene00011405 clec-155 Enriched in OLL; PVD; muscle cell; and in male based on microarray and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including aldicarb; methylmercuric chloride; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00011407 ppat-1 Predicted to enable amidophosphoribosyltransferase activity. Predicted to be involved in purine nucleotide biosynthetic process. Expressed in intestine. Is an ortholog of human PPAT (phosphoribosyl pyrophosphate amidotransferase). WB:WBGene00011408 nifk-1 Predicted to enable RNA binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Is an ortholog of human NIFK (nucleolar protein interacting with the FHA domain of MKI67). WB:WBGene00011409 T04A8.7 Predicted to enable 1,4-alpha-glucan branching enzyme activity. Predicted to be involved in glycogen biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease IV and pulmonary tuberculosis. Is an ortholog of human GBE1 (1,4-alpha-glucan branching enzyme 1). WB:WBGene00011410 T04A8.8 Enriched in ABaraapapp; ABaraappaa; ABaraapppp; germ line; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and let-7 based on microarray; proteomic; and RNA-seq studies. Is affected by ten chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ubiquitin-like domain superfamily; Rad60/SUMO-like domain; Ubiquitin-2 like Rad60 SUMO-like; and Phosphorylation site. WB:WBGene00011411 sel-13 Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in mitotic DNA damage checkpoint signaling; mitotic DNA replication checkpoint signaling; and nuclear DNA replication. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human ZNF830 (zinc finger protein 830). WB:WBGene00011412 mrpl-16 Predicted to enable rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL16 (mitochondrial ribosomal protein L16). WB:WBGene00011414 T04A8.13 Enriched in intestine; neurons; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Ethanol; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00011415 him-18 Enables enzyme binding activity and identical protein binding activity. Involved in DNA metabolic process; embryo development; and mitotic sister chromatid segregation. Located in nucleus. Part of Slx1-Slx4 complex. Expressed in germ line. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group P. Is an ortholog of human SLX4 (SLX4 structure-specific endonuclease subunit). WB:WBGene00011416 T04A11.1 Predicted to enable isomerase activity. Predicted to be involved in biosynthetic process. Predicted to be located in cytoplasm. Is an ortholog of human PBLD (phenazine biosynthesis like protein domain containing). WB:WBGene00011417 T04A11.2 Predicted to enable isomerase activity. Predicted to be involved in biosynthetic process. Predicted to be located in cytoplasm. Is an ortholog of human PBLD (phenazine biosynthesis like protein domain containing). WB:WBGene00011418 igdb-1 Predicted to be located in plasma membrane. WB:WBGene00011419 T04A11.4 Predicted to enable catalytic activity. Predicted to be involved in biosynthetic process. Is an ortholog of human PBLD (phenazine biosynthesis like protein domain containing). WB:WBGene00011420 T04A11.5 Predicted to enable catalytic activity. Predicted to be involved in biosynthetic process. Is an ortholog of human PBLD (phenazine biosynthesis like protein domain containing). WB:WBGene00011421 T04B2.1 Is affected by several genes including sir-2.1; alg-1; and cyc-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00011422 T04B2.3 Enriched in body wall musculature; muscle cell; neurons; pharynx; and somatic nervous system based on Chronogram; microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and let-60 based on RNA-seq; microarray; and proteomic studies. Is affected by fifteen chemicals including methylmercury hydroxide; rotenone; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011423 ipla-7 Predicted to enable calcium-independent phospholipase A2 activity and palmitoyl-CoA hydrolase activity. Predicted to be involved in positive regulation of ceramide biosynthetic process. Predicted to be located in mitochondrion. Expressed in intestine; pharyngeal-intestinal valve; pharynx; virL; and virR. WB:WBGene00011424 dhs-31 Predicted to enable oxidoreductase activity. Predicted to be located in cytoplasm. Expressed in hypodermis; vulB1; vulB2; vulD; and vulva. Is an ortholog of human CBR1 (carbonyl reductase 1) and CBR3 (carbonyl reductase 3). WB:WBGene00011425 T04B2.7 Enriched in neurons and in male based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00011426 T04C10.3 Enriched in neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-12; mex-1; and met-2 based on tiling array and RNA-seq studies. WB:WBGene00011427 T04C12.1 Predicted to be located in membrane. WB:WBGene00011428 nlp-80 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00011429 T04C12.7 Predicted to be located in membrane. WB:WBGene00011430 T04C12.8 Predicted to be located in membrane. WB:WBGene00011431 T04D3.1 Predicted to be involved in autophagy. Located in cytoplasm. WB:WBGene00011432 sdz-30 Predicted to be involved in autophagy. Located in cytoplasm. WB:WBGene00011433 pde-1 Enables 3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-GMP phosphodiesterase activity; and calmodulin binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of intracellular signal transduction; and response to alkaline pH. Expressed in AFDL; AFDR; and head. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 74. Is an ortholog of human PDE1A (phosphodiesterase 1A) and PDE1B (phosphodiesterase 1B). WB:WBGene00011434 T04D3.5 Expressed in germ line. WB:WBGene00011435 T04D3.8 Enriched in cholinergic neurons; germ line; pharyngeal cell; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00011436 T04F3.1 Predicted to enable transaminase activity. Predicted to be involved in amino acid metabolic process. Is an ortholog of human ACCS (1-aminocyclopropane-1-carboxylate synthase homolog (inactive)) and ACCSL (1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like). WB:WBGene00011437 smoc-1 Predicted to enable calcium ion binding activity. Expressed in hypodermis; pharyngeal-intestinal valve cell; and pharynx. Human ortholog(s) of this gene implicated in microphthalmia with limb anomalies. Is an ortholog of human SMOC1 (SPARC related modular calcium binding 1) and SMOC2 (SPARC related modular calcium binding 2). WB:WBGene00011438 T04F3.3 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00011439 T04F3.4 Predicted to enable calcium ion binding activity. WB:WBGene00011440 sfxn-1.5 Predicted to enable serine transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Predicted to be located in mitochondrial membrane. Is an ortholog of human SFXN1 (sideroflexin 1) and SFXN3 (sideroflexin 3). WB:WBGene00011441 T04F8.2 Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be located in membrane. Is an ortholog of human GPR180 (G protein-coupled receptor 180). WB:WBGene00011442 T04F8.3 Enriched in distal tip cell; excretory gland cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by mianserin; Atrazine; and Quercetin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Ubiquitin-like domain superfamily. WB:WBGene00011443 cutl-11 Predicted to be located in membrane. WB:WBGene00011444 noca-2 Predicted to be involved in microtubule anchoring at centrosome. Predicted to be located in centrosome. Human ortholog(s) of this gene implicated in Seckel syndrome 7. Is an ortholog of human NIN (ninein) and NINL (ninein like). WB:WBGene00011445 T04F8.7 Enriched in AVL; head mesodermal cell; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Tunicamycin; Cry5B; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SH3-like domain superfamily and Phosphorylation site. WB:WBGene00011446 T04F8.8 Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. WB:WBGene00011447 T04F8.9 Predicted to be located in membrane. WB:WBGene00011448 tag-348 Expressed in body wall musculature and vulval muscle. WB:WBGene00011449 slfl-5 Enables identical protein binding activity. Predicted to be involved in translational elongation. Expressed in gonad. Is an ortholog of human GTPBP2 (GTP binding protein 2). WB:WBGene00011450 ttr-22 Predicted to be located in cell surface and extracellular region. WB:WBGene00011451 T04H1.5 Predicted to enable nucleic acid binding activity. Predicted to be located in kinetochore. Is an ortholog of human GPATCH11 (G-patch domain containing 11). WB:WBGene00011452 ugt-55 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1); UGT3A2 (UDP glycosyltransferase family 3 member A2); and UGT8 (UDP glycosyltransferase 8). WB:WBGene00011453 ugt-56 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Expressed in ASEL; ASER; ASHL; ASHR; and nervous system. WB:WBGene00011454 lron-14 Predicted to enable potassium channel activator activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Expressed in head neurons. Is an ortholog of human CHADL (chondroadherin like). WB:WBGene00011455 T05A1.4 No description available WB:WBGene00011456 T05A1.5 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00011458 irld-47 Enriched in ABplapaaaap; ABprapaaaap; ASJ; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by copper sulfate based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00011459 T05A6.5 Is affected by several genes including let-60; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00011460 ttr-14 Predicted to be located in cell surface and extracellular region. WB:WBGene00011462 vap-2 Predicted to be located in extracellular space. WB:WBGene00011463 T05A10.6 Enriched in g1 and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; D-glucose; and cholesterol based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CAP superfamily. WB:WBGene00011464 T05B9.1 Enriched in several structures, including germ line; germline precursor cell; head mesodermal cell; neurons; and pharyngeal muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and gld-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by ten chemicals including manganese chloride; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011465 T05B9.2 Enriched in neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; lin-35; and lin-28 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00011466 T05C12.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00011467 decr-1.3 Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Is an ortholog of human DECR1 (2,4-dienoyl-CoA reductase 1). WB:WBGene00011468 T05C12.4 Predicted to be located in membrane. WB:WBGene00011469 dylt-3 Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be located in cytoplasm. Predicted to be part of cytoplasmic dynein complex. Expressed in ciliated neurons and pharyngeal muscle cell. WB:WBGene00011470 C08E8.t3 No description available WB:WBGene00011471 T05C12.8 Enriched in B cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by bortezomib; cadmium; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ankyrin repeat-containing domain superfamily and Phosphorylation site. WB:WBGene00011472 T05C12.9 Predicted to be located in membrane. WB:WBGene00011473 T05C12.11 Predicted to be located in membrane. WB:WBGene00011474 aldo-1 Enables fructose-bisphosphate aldolase activity and identical protein binding activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Expressed in gonad; intestinal muscle; and spermathecal-uterine valve cell. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; hereditary fructose intolerance syndrome; and type 2 diabetes mellitus. Is an ortholog of human ALDOA (aldolase, fructose-bisphosphate A) and ALDOC (aldolase, fructose-bisphosphate C). WB:WBGene00011475 T05D4.2 Enriched in several structures, including ABalaaaarl; ABalaaaarr; VC neuron; head mesodermal cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00011476 exc-12 Predicted to enable adenylate cyclase activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and cAMP biosynthetic process. Predicted to be located in membrane. WB:WBGene00011478 T05D4.5 Predicted to be located in cytoskeleton. WB:WBGene00011479 clc-9 Predicted to be located in plasma membrane. WB:WBGene00011480 enpl-1 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding and ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum and perinuclear region of cytoplasm. Expressed in head; neurons; pharynx; and vulva. Human ortholog(s) of this gene implicated in lung adenocarcinoma. Is an ortholog of human HSP90B1 (heat shock protein 90 beta family member 1). WB:WBGene00011481 imp-2 Enables aspartic endopeptidase activity, intramembrane cleaving. Involved in ecdysis, collagen and cuticulin-based cuticle; proteolysis; and regulation of multicellular organismal development. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human HM13 (histocompatibility minor 13). WB:WBGene00011482 pigk-1 Predicted to enable GPI-anchor transamidase activity. Predicted to be involved in attachment of GPI anchor to protein. Predicted to be part of GPI-anchor transamidase complex. Is an ortholog of human PIGK (phosphatidylinositol glycan anchor biosynthesis class K). WB:WBGene00011483 T05E11.7 Enriched in DA neuron and VA neuron based on tiling array studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00011484 srlf-24 Enriched in several structures, including ABalppappa; ABarappppa; ABplpppaaa; PVR; and amphid sheath cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including methylmercuric chloride; rotenone; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00011485 srbc-14 Predicted to be located in membrane. WB:WBGene00011486 T05E12.3 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00011487 T05E12.6 Enriched in ABaraapapaa; ABaraapppaa; intestine; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-two chemicals including Heme; diallyl trisulfide; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00011488 nra-2 Involved in protein-containing complex assembly and regulation of protein targeting to membrane. Located in endoplasmic reticulum. Expressed in body wall musculature; egg-laying apparatus; excretory canal; neurons; and pharyngeal muscle cell. Is an ortholog of human NCLN (nicalin). WB:WBGene00011489 T05F1.2 Expressed in germ line. WB:WBGene00011490 T05F1.4 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalaapppa; ABalapaapa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011491 T05F1.5 Enriched in amphid sheath cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-two chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00011492 T05F1.7 Enriched in CEM; HOB; IL2 neuron; neurons; and ray neuron type B based on RNA-seq studies. Is affected by several genes including unc-30; alg-1; and wdr-23 based on RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00011493 T05F1.8 Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human SLC25A3 (solute carrier family 25 member 3). WB:WBGene00011494 T05F1.9 Enriched in B cell; anal sphincter muscle; hypodermis; intestine; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including 1-methylnicotinamide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00011495 T05F1.11 Enriched in RMED; cholinergic neurons; intestine; and mechanosensory neurons based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eleven chemicals including rotenone; Tunicamycin; and Neurotoxins based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Thioredoxin-like superfamily; Thioredoxin-like; and Phosphorylation site. WB:WBGene00011496 T05F1.12 No description available WB:WBGene00011497 T05F1.13 Enriched in body wall muscle cell and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Rifampin; paraquat; and Diazinon based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; F-box-like domain superfamily; and F-box domain. WB:WBGene00011498 T05G5.1 Predicted to be located in membrane. WB:WBGene00011499 T05G5.4 Predicted to be located in membrane. WB:WBGene00011500 T05G5.5 Predicted to enable dephospho-CoA kinase activity. Predicted to be involved in coenzyme A biosynthetic process. Located in mitochondrion. Is an ortholog of human DCAKD (dephospho-CoA kinase domain containing). WB:WBGene00011501 rmd-1 Enables kinase binding activity. Involved in attachment of mitotic spindle microtubules to kinetochore and mitotic spindle organization. Located in mitotic spindle pole and spindle microtubule. Expressed in germ line. Is an ortholog of human RMDN1 (regulator of microtubule dynamics 1); RMDN2 (regulator of microtubule dynamics 2); and RMDN3 (regulator of microtubule dynamics 3). WB:WBGene00011502 vps-53 Involved in positive regulation of locomotion involved in locomotory behavior; regulation of brood size; and regulation of dense core granule transport. Located in perikaryon and perinuclear region of cytoplasm. Part of GARP complex. Expressed in body wall musculature; intestine; and pharynx. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2E. Is an ortholog of human VPS53 (VPS53 subunit of GARP complex). WB:WBGene00011503 gcc-2 Predicted to be located in Golgi apparatus. Is an ortholog of human GCC2 (GRIP and coiled-coil domain containing 2). WB:WBGene00011505 pzf-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in meiotic chromosome segregation and positive regulation of meiotic cell cycle. Predicted to be located in nucleus. Expressed in gonad. WB:WBGene00011506 srbc-77 Predicted to be located in membrane. WB:WBGene00011507 T05H10.1 Predicted to enable cysteine-type deubiquitinase activity. Involved in anterior/posterior axis specification, embryo. Located in cytoplasm. Expressed in germ line. Is an ortholog of human USP47 (ubiquitin specific peptidase 47). WB:WBGene00011508 T05H10.3 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and Caappd based on Chronogram; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirty-two chemicals including cholesterol; lathosterol; and aldicarb based on microarray; RNA-seq; and proteomic studies. WB:WBGene00011509 T05H10.4 Enriched in several structures, including GLR; germ line; interfacial epithelial cell; male distal tip cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including methylmercury hydroxide; manganese chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011510 pdha-1 Predicted to enable pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency and spermatogenic failure. Is an ortholog of human PDHA1 (pyruvate dehydrogenase E1 subunit alpha 1) and PDHA2 (pyruvate dehydrogenase E1 subunit alpha 2). WB:WBGene00011511 gpcp-2 Predicted to enable glycerophosphocholine phosphodiesterase activity. Predicted to be involved in glycerophospholipid catabolic process. Is an ortholog of human GPCPD1 (glycerophosphocholine phosphodiesterase 1). WB:WBGene00011512 T05H10.8 Enriched in ABplpppaaa; ABprpppaaa; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Peroxiredoxin-like 2A/B/C; AhpC/TSA antioxidant enzyme; and Phosphorylation site. WB:WBGene00011513 fbxa-197 Enriched in several structures, including I5 neuron; cholinergic neurons; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; manganese chloride; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00011514 fbxa-198 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00011515 oac-42 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00011516 T06C12.9 Predicted to be located in membrane. WB:WBGene00011517 cgt-1 Predicted to enable ceramide glucosyltransferase activity. Involved in glucosylceramide biosynthetic process; nematode larval development; and regulation of protein localization to basolateral plasma membrane. Predicted to be located in membrane. Expressed in several structures, including excretory system; pharyngeal muscle cell; pharyngeal-intestinal valve; rectal gland cell; and rectal valve cell. Is an ortholog of human UGCG (UDP-glucose ceramide glucosyltransferase). WB:WBGene00011518 T06C12.11 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00011519 T06C12.12 Predicted to be located in membrane. WB:WBGene00011520 nhr-213 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in several structures, including excretory system; intestine; pharynx; somatic nervous system; and vulva. WB:WBGene00011521 T06C12.14 Enriched in AFD; MSaaaaapa; MSaapaapa; MSpapaapa; and g1 based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and elt-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including silicon dioxide nanoparticle; rotenone; and resveratrol based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00011522 srap-1 Expressed in cuticle; nervous system; seam cell; syncytium; and vulva. Is predicted to encode a protein with the following domains: Repeat of unknown function (DUF1174); PAN/Apple domain; and Repeat of unknown function DUF1174. WB:WBGene00011523 T06D8.2 Predicted to be located in cilium. Human ortholog(s) of this gene implicated in Joubert syndrome 25 and autosomal recessive intellectual developmental disorder 77. Is an ortholog of human CEP104 (centrosomal protein 104). WB:WBGene00011524 plpr-1 Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. Is an ortholog of human PLPPR1 (phospholipid phosphatase related 1) and PLPPR5 (phospholipid phosphatase related 5). WB:WBGene00011525 T06D8.4 No description available WB:WBGene00011526 cox-15 Predicted to enable oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme A biosynthetic process. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Leigh disease; hypertrophic cardiomyopathy; and mitochondrial complex IV deficiency nuclear type 6. Is an ortholog of human COX15 (cytochrome c oxidase assembly homolog COX15). WB:WBGene00011527 cchl-1 Predicted to enable holocytochrome-c synthase activity. Located in mitochondrion. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 1 and microphthalmia. Is an ortholog of human HCCS (holocytochrome c synthase). WB:WBGene00011528 fndc-1 Involved in mitophagy. Predicted to be located in mitochondrial outer membrane. Is an ortholog of human FUNDC1 (FUN14 domain containing 1) and FUNDC2 (FUN14 domain containing 2). WB:WBGene00011529 T06D8.9 Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human SARAF (store-operated calcium entry associated regulatory factor). WB:WBGene00011530 T06D8.10 Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. WB:WBGene00011531 rsbp-1 Predicted to be involved in G protein-coupled receptor signaling pathway. Located in cell body and neuron projection. Expressed in body wall musculature; muscle cell; nervous system; pharynx; and vulva. WB:WBGene00011532 chaf-1 Predicted to be involved in nucleosome assembly. Predicted to be located in nucleus. Predicted to be part of CAF-1 complex. Human ortholog(s) of this gene implicated in several diseases, including colon cancer; neuroblastoma; and systemic lupus erythematosus. Is an ortholog of human CHAF1A (chromatin assembly factor 1 subunit A). WB:WBGene00011533 T06E4.5 Predicted to be located in membrane. WB:WBGene00011534 T06E4.7 Predicted to be located in membrane. WB:WBGene00011535 idpc-5 Involved in endoplasmic reticulum unfolded protein response. Acts upstream of or within IRE1-mediated unfolded protein response. WB:WBGene00011536 idpc-6 Enriched in arc ant V; arcade cell; germ line; intestine; and pharynx based on microarray; proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; methylmercury hydroxide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00011537 idpc-7 Enriched in arcade cell; intestine; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq and microarray studies. WB:WBGene00011538 T06E6.1 Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human WDR74 (WD repeat domain 74). WB:WBGene00011539 fbxa-135 Enriched in DA neuron; VA neuron; intestine; neurons; and pharyngeal muscle cell based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box domain. WB:WBGene00011540 T06E6.10 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00011541 srbc-63 Predicted to be located in membrane. WB:WBGene00011542 fbxa-104 Enriched in intestine based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and csr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by four chemicals including stearic acid; sucrose; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00011543 acl-2 Predicted to enable 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidic acid biosynthetic process. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 1. Is an ortholog of human AGPAT1 (1-acylglycerol-3-phosphate O-acyltransferase 1) and AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2). WB:WBGene00011544 T06E8.2 Is affected by several genes including daf-12; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Sirolimus and nitroguanidine based on microarray studies. WB:WBGene00011545 T06G6.3 Enriched in intestine; neurons; and oxygen sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; proteomic; and microarray studies. Is affected by several genes including skn-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00011546 T06G6.4 Enriched in several structures, including Z1.p; Z4.a; male distal tip cell; neurons; and somatic gonad precursor based on RNA-seq; proteomic; and microarray studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00011547 T06G6.5 Expressed in coelomocyte; head muscle; head neurons; intestine; and tail neurons. WB:WBGene00011548 T06G6.6 Enriched in OLL; PVD; hypodermis; seam cell; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00011549 T06G6.8 Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Rifampin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00011550 T06G6.11 Is affected by several genes including daf-16; clk-1; and nhr-25 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00011551 T06G6.12 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00011554 T07A5.1 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Is an ortholog of human FKTN (fukutin). WB:WBGene00011556 vglu-3 Predicted to enable L-glutamate transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Predicted to be involved in several processes, including glutamatergic synaptic transmission; monoatomic anion transport; and neurotransmitter loading into synaptic vesicle. Predicted to be located in excitatory synapse. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Is an ortholog of human SLC17A6 (solute carrier family 17 member 6); SLC17A7 (solute carrier family 17 member 7); and SLC17A8 (solute carrier family 17 member 8). WB:WBGene00011557 T07A5.4 Is affected by several genes including eat-2; alg-1; and csr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and bortezomib based on RNA-seq studies. WB:WBGene00011558 ostf-4 Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human OST4 (oligosaccharyltransferase complex subunit 4, non-catalytic). WB:WBGene00011559 umps-1 Enables orotate phosphoribosyltransferase activity and orotidine-5'-phosphate decarboxylase activity. Involved in several processes, including determination of adult lifespan; pyrimidine-containing compound biosynthetic process; and response to radiation. Located in cytoplasm. Expressed in head; intestine; neurons; and tail. Used to study orotic aciduria. Human ortholog(s) of this gene implicated in orotic aciduria and purine-pyrimidine metabolic disorder. Is an ortholog of human UMPS (uridine monophosphate synthetase). WB:WBGene00011560 T07C4.3 Enriched in several structures, including RIC; distal tip cell; germ line; head mesodermal cell; and pharyngeal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; glp-1; and gld-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including bisphenol S; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011561 ttr-15 Predicted to be located in cell surface and extracellular region. WB:WBGene00011562 sas-7 Predicted to be located in centriole and cytoplasm. WB:WBGene00011563 jmjd-4 Predicted to enable 2-oxoglutarate-dependent dioxygenase activity and sequence-specific DNA binding activity. Predicted to be involved in positive regulation of translational termination. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human JMJD4 (jumonji domain containing 4). WB:WBGene00011564 ugt-50 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Expressed in PVQ; intestine; and lateral ganglion. WB:WBGene00011565 nhr-272 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00011566 nhr-214 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons. WB:WBGene00011567 nhr-215 Enriched in AFD; ASER; PLM; and neurons based on RNA-seq and microarray studies. Is affected by several genes including eat-2; clk-1; and alg-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00011568 nhr-26 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00011569 T07C12.2 No description available WB:WBGene00011570 sre-28 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head. WB:WBGene00011571 ttr-46 Predicted to be located in cell surface and extracellular region. WB:WBGene00011572 mam-5 Predicted to be located in membrane. WB:WBGene00011573 anmt-3 Predicted to enable N-methyltransferase activity. Predicted to be located in cytosol. Expressed in body wall musculature and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in renal cell carcinoma. Is an ortholog of human NNMT (nicotinamide N-methyltransferase). WB:WBGene00011574 T07C12.10 Enriched in muscle cell and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by cadmium and tetrabromobisphenol A based on microarray studies. WB:WBGene00011575 madf-4 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. WB:WBGene00011576 rmh-2 Predicted to enable nucleotide binding activity. Involved in larval development. Predicted to be located in nuclear body. Predicted to be part of RecQ family helicase-topoisomerase III complex. Is an ortholog of human RMI1 (RecQ mediated genome instability 1). WB:WBGene00011577 fipr-12 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. WB:WBGene00011578 npr-20 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and lung disease (multiple). Is an ortholog of several human genes including CCR1 (C-C motif chemokine receptor 1); CCR3 (C-C motif chemokine receptor 3); and CXCR5 (C-X-C motif chemokine receptor 5). WB:WBGene00011579 T07D4.2 Predicted to enable hydrolase activity. Is an ortholog of human MPPED1 (metallophosphoesterase domain containing 1) and MPPED2 (metallophosphoesterase domain containing 2). WB:WBGene00011580 ddx-19 Predicted to enable RNA binding activity and RNA helicase activity. Involved in germ cell development. Located in P granule. Expressed in tail. Is an ortholog of human DDX19A (DEAD-box helicase 19A) and DDX19B (DEAD-box helicase 19B). WB:WBGene00011581 T07D10.1 Predicted to be located in membrane. WB:WBGene00011582 ntr-1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in intestine and neurons. Human ortholog(s) of this gene implicated in several diseases, including ACTH-secreting pituitary adenoma; X-linked recessive disease (multiple); and portal hypertension. Is an ortholog of several human genes including AVPR1A (arginine vasopressin receptor 1A); AVPR1B (arginine vasopressin receptor 1B); and AVPR2 (arginine vasopressin receptor 2). WB:WBGene00011583 T07D10.3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00011584 clec-15 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eight chemicals including Oligosaccharides; cadmium; and Quercetin based on microarray studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00011585 clec-16 Is affected by several genes including daf-16; daf-18; and rrf-1 based on RNA-seq and microarray studies. Is affected by five chemicals including cadmium; Colistin; and 2 based on microarray studies. WB:WBGene00011586 flp-33 Enriched in G2; W cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; microarray; and proteomic studies. Is affected by nine chemicals including 1-methylnicotinamide; rotenone; and D-glucose based on RNA-seq studies. WB:WBGene00011587 anp-1 Enables metalloaminopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including severe acute respiratory syndrome; severe pre-eclampsia; and uterine disease (multiple). Is an ortholog of several human genes including ANPEP (alanyl aminopeptidase, membrane); ENPEP (glutamyl aminopeptidase); and LNPEP (leucyl and cystinyl aminopeptidase). WB:WBGene00011589 T07F10.3 Predicted to enable RNA binding activity. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human TRNAU1AP (tRNA selenocysteine 1 associated protein 1). WB:WBGene00011590 bus-19 Predicted to be located in membrane. Is an ortholog of human TMEM41A (transmembrane protein 41A). WB:WBGene00011591 T07F10.5 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in mitotic cell cycle phase transition. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin A2-CDK2 complex. WB:WBGene00011592 nspg-1 Enriched in several structures, including ABplppppaa; ABprppppaa; corpus; interfacial epithelial cell; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; dcr-1; and isp-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00011593 T07G12.2 Predicted to enable L-ascorbic acid transmembrane transporter activity. Predicted to be involved in L-ascorbic acid transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC23A1 (solute carrier family 23 member 1) and SLC23A2 (solute carrier family 23 member 2). WB:WBGene00011594 T07G12.3 Predicted to be located in membrane. WB:WBGene00011595 T07G12.4 Predicted to enable L-ascorbic acid transmembrane transporter activity. Predicted to be involved in L-ascorbic acid transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC23A2 (solute carrier family 23 member 2). WB:WBGene00011596 T07G12.5 Predicted to enable L-ascorbic acid transmembrane transporter activity. Predicted to be involved in L-ascorbic acid transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC23A2 (solute carrier family 23 member 2). WB:WBGene00011597 zim-1 Predicted to be involved in meiotic chromosome segregation. Located in condensed nuclear chromosome. WB:WBGene00011598 T07G12.7 No description available WB:WBGene00011599 T07G12.8 Enriched in germ line; sensory neurons; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011600 zim-2 Predicted to be involved in meiotic chromosome segregation. Located in condensed nuclear chromosome. WB:WBGene00011601 zim-3 Predicted to be involved in meiotic chromosome segregation. Located in condensed nuclear chromosome. WB:WBGene00011604 T08A11.1 Predicted to contribute to GTPase activator activity. Predicted to be involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and positive regulation of autophagy. Predicted to be located in lysosomal membrane. Predicted to be part of GATOR1 complex. Human ortholog(s) of this gene implicated in focal epilepsy. Is an ortholog of human DEPDC5 (DEP domain containing 5, GATOR1 subcomplex subunit). WB:WBGene00011605 sftb-1 Predicted to enable mRNA binding activity. Involved in negative regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of U2 snRNP; U2-type prespliceosome; and catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and myelodysplastic syndrome. Is an ortholog of human SF3B1 (splicing factor 3b subunit 1). WB:WBGene00011606 tmed-12 Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human TMED4 (transmembrane p24 trafficking protein 4). WB:WBGene00011607 T08D2.2 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Alovudine based on RNA-seq studies. WB:WBGene00011608 T08D2.3 Enriched in AVK and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by Rifampin; Sirolimus; and allantoin based on RNA-seq studies. WB:WBGene00011609 T08D2.4 Predicted to enable metal ion binding activity. WB:WBGene00011610 T08D2.5 Enriched in AFD; germline precursor cell; hypodermis; and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; D-glucose; and tert-Butylhydroperoxide based on microarray and RNA-seq studies. WB:WBGene00011611 T08D2.6 Enriched in ABalppppppp and ABpraaapppp based on single-cell RNA-seq studies. Is affected by several genes including daf-16; age-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Alovudine; stavudine; and paraquat based on RNA-seq studies. WB:WBGene00011612 chkr-1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mitotic DNA damage checkpoint signaling. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Li-Fraumeni syndrome 2; breast cancer (multiple); and germ cell cancer (multiple). Is an ortholog of human CHEK2 (checkpoint kinase 2). WB:WBGene00011613 T08D2.8 Predicted to enable microtubule plus end polymerase and microtubule plus-end binding activity. Predicted to be involved in establishment or maintenance of microtubule cytoskeleton polarity; microtubule polymerization; and spindle organization. Predicted to be located in intracellular non-membrane-bounded organelle and supramolecular complex. WB:WBGene00011614 nfya-1 Enables DNA-binding transcription repressor activity. Involved in positive regulation of nematode male tail tip morphogenesis; regulation of gene expression; and tissue development. Located in nucleus. Expressed in several structures, including excretory cell; gonad; head neurons; oocyte; and somatic nervous system. Used to study cancer. Is an ortholog of human NFYA (nuclear transcription factor Y subunit alpha). WB:WBGene00011615 lsd-1 Predicted to enable chromatin binding activity; flavin adenine dinucleotide binding activity; and oxidoreductase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in membrane and nucleus. Human ortholog(s) of this gene implicated in several diseases, including alopecia areata; diabetic retinopathy; and hepatocellular carcinoma. Is an ortholog of human KDM1A (lysine demethylase 1A). WB:WBGene00011616 T08D10.3 Enriched in coelomocyte based on tiling array studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by ten chemicals including Tunicamycin; D-glucose; and Zidovudine based on RNA-seq studies. WB:WBGene00011617 T08G3.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including nicotinic acid; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00011618 T08G3.6 Is affected by several genes including rrf-3; csr-1; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Diazinon and adsorbable organic bromine compound based on microarray studies. WB:WBGene00011619 T08G3.7 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00011620 T08G3.11 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including nhr-49; eri-1; and mdt-15 based on tiling array; RNA-seq; and microarray studies. Is affected by Ag nanoparticles; Atrazine; and fluoranthene based on RNA-seq and microarray studies. WB:WBGene00011621 T08G3.13 Predicted to be involved in protein homooligomerization. Is an ortholog of human KCTD10 (potassium channel tetramerization domain containing 10) and TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00011622 T08G5.1 Enriched in intestine; male-specific anatomical entity; and neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Mercuric Chloride; Tunicamycin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00011623 T08G5.2 Is affected by several genes including pie-1; lin-4; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00011624 T08G5.3 Enriched in PLM; muscle cell; seam cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00011625 vps-39 Predicted to be involved in autophagy and endosomal vesicle fusion. Predicted to be located in cytoplasm and membrane. Predicted to be part of HOPS complex. Is an ortholog of human VPS39 (VPS39 subunit of HOPS complex). WB:WBGene00011626 T08G5.7 Enriched in ASER based on RNA-seq studies. Is affected by cyc-1; mir-34; and mex-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00011627 T08G5.8 Is affected by several genes including eat-2; sir-2.1; and pptr-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00011628 T08G5.9 Is affected by several genes including sir-2.1; nuo-6; and pptr-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00011629 T08G11.1 Predicted to be involved in protein retention in Golgi apparatus and protein targeting to vacuole. Predicted to be extrinsic component of membrane. Expressed in vulval muscle. Human ortholog(s) of this gene implicated in Parkinson's disease 23; choreaacanthocytosis; and choreatic disease. Is an ortholog of human VPS13A (vacuolar protein sorting 13 homolog A). WB:WBGene00011630 T08G11.3 Predicted to enable microtubule binding activity. Predicted to be located in microtubule cytoskeleton and sperm flagellum. Is an ortholog of human SAXO1 (stabilizer of axonemal microtubules 1) and SAXO2 (stabilizer of axonemal microtubules 2). WB:WBGene00011631 tgs-1 Predicted to enable RNA trimethylguanosine synthase activity. Predicted to be involved in 7-methylguanosine cap hypermethylation. Predicted to be located in nucleus. Is an ortholog of human TGS1 (trimethylguanosine synthase 1). WB:WBGene00011633 T09A5.4 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and Caappd based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; rotenone; and Atrazine based on microarray and RNA-seq studies. WB:WBGene00011634 T09A5.5 Located in mitochondrion. WB:WBGene00011635 mdmh-35 Enriched in body wall muscle cell; germ line; and neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and clk-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq and microarray studies. Human TRIAP1 Contributes to phosphatidic acid transfer activity. Human TRIAP1 enables p53 binding activity. Is predicted to encode a protein with the following domains: Mitochondrial distribution/morphology family 35/apoptosis and Uncharacterised protein family (UPF0203). Is an ortholog of human TRIAP1 (TP53 regulated inhibitor of apoptosis 1). WB:WBGene00011636 cec-3 Predicted to enable chromatin binding activity and methylated histone binding activity. Involved in negative regulation of gene expression. Located in nucleus. WB:WBGene00011637 sds-22 Involved in negative regulation of centriole replication. Predicted to be located in cytoplasm. Is an ortholog of human PPP1R7 (protein phosphatase 1 regulatory subunit 7). WB:WBGene00011638 ostb-1 Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ir. Is an ortholog of human DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit). WB:WBGene00011639 ztf-17 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of PcG protein complex and transcription regulator complex. Expressed in body wall musculature; gonad; intestine; pharynx; and ventral nerve cord. Is an ortholog of human ZFP42 (ZFP42 zinc finger protein). WB:WBGene00011640 T09A5.14 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00011641 T09A5.15 Predicted to be located in membrane. WB:WBGene00011642 T09B9.1 Predicted to enable carboxylic ester hydrolase activity. Predicted to be located in membrane. Is an ortholog of human AADACL3 (arylacetamide deacetylase like 3). WB:WBGene00011643 slc-17.9 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be located in membrane. WB:WBGene00011644 T09B9.3 Predicted to enable glycerophosphodiester phosphodiesterase activity. Predicted to be involved in N-acylethanolamine metabolic process; ethanolamine metabolic process; and phospholipid metabolic process. Predicted to be located in plasma membrane. Is an ortholog of human GDE1 (glycerophosphodiester phosphodiesterase 1). WB:WBGene00011645 T09B9.4 Enriched in several structures, including carbon dioxide sensory neurons; cephalic sheath cell; germ line; germline precursor cell; and male distal tip cell based on RNA-seq and microarray studies. Is affected by several genes including glp-1; dpy-10; and daf-12 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by four chemicals including paraquat; resveratrol; and Hydrolyzable Tannins based on RNA-seq and microarray studies. Human CCDC6 enables identical protein binding activity. Is predicted to encode a protein with the following domains: Uncharacterized conserved protein H4 (DUF2046); Protein of unknown function DUF2046; and Phosphorylation site. Is an ortholog of human CCDC6 (coiled-coil domain containing 6). WB:WBGene00011646 T09B9.5 Predicted to be located in membrane. WB:WBGene00011647 noca-1 Involved in cytoplasmic microtubule organization; germ cell development; and nematode larval development. Located in microtubule. Expressed in hyp7 syncytium and intestinal cell. WB:WBGene00011648 cni-1 Enables signaling receptor binding activity. Involved in negative regulation of anterograde synaptic vesicle transport; negative regulation of receptor localization to synapse; and positive regulation of ERAD pathway. Located in several cellular components, including Golgi apparatus; perinuclear endoplasmic reticulum; and somatodendritic compartment. Expressed in AVAL; AVAR; and nervous system. Is an ortholog of human CNIH1 (cornichon family AMPA receptor auxiliary protein 1) and CNIH2 (cornichon family AMPA receptor auxiliary protein 2). WB:WBGene00011649 T09E8.4 Predicted to be located in membrane. WB:WBGene00011650 glct-1 Predicted to enable galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity. Predicted to be involved in carbohydrate metabolic process and chondroitin sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in Barrett's esophagus and schizophrenia. Is an ortholog of human B3GAT1 (beta-1,3-glucuronyltransferase 1) and B3GAT2 (beta-1,3-glucuronyltransferase 2). WB:WBGene00011651 nhr-217 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00011652 T09E11.3 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00011653 oac-43 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00011654 oac-44 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00011655 T09E11.6 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00011656 oac-45 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00011657 T09E11.8 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00011658 T09E11.9 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00011659 T09E11.10 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. WB:WBGene00011660 T09E11.11 Enriched in OLL; PVD; head mesodermal cell; and intestine based on microarray and RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; rotenone; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00011661 ztf-27 Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. WB:WBGene00011662 T09F3.2 Predicted to enable pyrimidine nucleotide transmembrane transporter activity. Predicted to be involved in mitochondrial genome maintenance and pyrimidine nucleotide import into mitochondrion. Predicted to be located in mitochondrion. Expressed in head and tail. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 8. Is an ortholog of human SLC25A33 (solute carrier family 25 member 33) and SLC25A36 (solute carrier family 25 member 36). WB:WBGene00011663 T09F3.4 Predicted to enable RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer. Predicted to be located in ribosome. WB:WBGene00011664 T09F3.5 Predicted to enable RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer. WB:WBGene00011665 T09F5.1 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. WB:WBGene00011666 T09F5.2 Predicted to be located in membrane. WB:WBGene00011667 T09F5.7 No description available WB:WBGene00011668 clec-47 Predicted to enable carbohydrate binding activity. Involved in response to gamma radiation. Predicted to be located in external side of plasma membrane. WB:WBGene00011669 T09F5.10 Enriched in hypodermis and in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and lin-4 based on microarray; RNA-seq; and tiling array studies. Is affected by fourteen chemicals including Ethanol; tryptophan; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF1248 and Protein of unknown function (DUF1248). WB:WBGene00011670 fbxa-84 Enriched in AVG and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00011671 cyp-13A4 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00011672 cyp-13A5 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00011673 cyp-13A6 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00011674 cyp-13A8 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Expressed in hypodermis and pharynx. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00011675 cyp-13A3 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00011676 cyp-13A2 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00011677 cyp-13A1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00011678 T10B9.9 Enriched in ABaraapapaa; ABaraapppaa; neurons; retrovesicular ganglion; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including clk-1; pgl-1; and mex-3 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; multi-walled carbon nanotube; and metformin based on RNA-seq studies. WB:WBGene00011679 ucr-2.2 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 5. Is an ortholog of human UQCRC2 (ubiquinol-cytochrome c reductase core protein 2). WB:WBGene00011680 pkhm-2 Predicted to enable kinesin binding activity. Predicted to be involved in Golgi organization; lysosome localization; and regulation of protein localization. Predicted to be located in endosome membrane. Expressed in anterior gonad arm. WB:WBGene00011681 T10B10.4 Predicted to enable N-acyltransferase activity. Located in endoplasmic reticulum. Is an ortholog of several human genes including GLYAT (glycine-N-acyltransferase); GLYATL1 (glycine-N-acyltransferase like 1); and GLYATL2 (glycine-N-acyltransferase like 2). WB:WBGene00011682 snt-7 Predicted to enable several functions, including SNARE binding activity; calcium ion binding activity; and phospholipid binding activity. Predicted to be involved in calcium-ion regulated exocytosis; cellular response to calcium ion; and regulation of secretion by cell. Predicted to be located in exocytic vesicle and plasma membrane. WB:WBGene00011683 phat-6 Involved in pharyngeal gland morphogenesis. Expressed in g1AL; g1AR; g1P; g2L; and g2R. WB:WBGene00011684 T10B10.8 Predicted to enable glycosyltransferase activity. Predicted to be located in cytoplasm. WB:WBGene00011685 T10B10.9 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00011686 T10C6.2 Is affected by lsm-1 and sir-2.1 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00011687 cwc-15 Predicted to enable RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Located in nucleus. Expressed in hypodermis; neurons; spermatheca; and vulva. Is an ortholog of human CWC15 (CWC15 spliceosome associated protein homolog). WB:WBGene00011688 T10C6.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in plasma membrane. Is an ortholog of human SLC37A3 (solute carrier family 37 member 3). WB:WBGene00011689 T10C6.7 Enriched in several structures, including ABplpppppp; ganglia; germ line; interfacial epithelial cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00011690 T10C6.9 Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011691 T10C6.10 Enriched in anterior hypodermis; arc ant V; cephalic sheath cell; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and sir-2.1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; Tunicamycin; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00011692 T10G3.1 Enriched in head mesodermal cell; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Cry5B; levamisole; and stavudine based on RNA-seq and microarray studies. WB:WBGene00011693 T10G3.2 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00011694 T10G3.3 Enriched in G2; W cell; and seam cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Tunicamycin; D-glucopyranose; and bisphenol S based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Abnormal cell migration protein 18-like and Phosphorylation site. WB:WBGene00011695 T10G3.4 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00011696 eea-1 Enables phosphatidylinositol-3-phosphate binding activity. Involved in endocytosis. Located in early endosome and endocytic vesicle. Expressed in hypodermis and intestine. Is an ortholog of human EEA1 (early endosome antigen 1). WB:WBGene00011697 T10H4.4 Predicted to be located in cytoplasm. Is an ortholog of human PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like). WB:WBGene00011698 cyp-34A1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and rhinitis. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2F1 (cytochrome P450 family 2 subfamily F member 1). WB:WBGene00011699 cyp-34A2 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); hematologic cancer (multiple); and renal fibrosis. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2J2 (cytochrome P450 family 2 subfamily J member 2). WB:WBGene00011701 srab-17 Predicted to be located in membrane. WB:WBGene00011702 srab-18 Predicted to be located in membrane. WB:WBGene00011703 srab-19 Is affected by several genes including lin-4; eat-2; and lin-14 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00011704 sdz-31 Involved in gastrulation. Predicted to be located in membrane. Expressed in several structures, including E; Ea; Ep; MSaa; and MSpa. WB:WBGene00011705 clp-9 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Expressed in tail. Is an ortholog of human CAPN15 (calpain 15). WB:WBGene00011706 T11B7.1 Enriched in several structures, including ABplpappaa; ABplpapppa; AVK; body wall muscle cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including methylmercury hydroxide; methylmercuric chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00011707 T11B7.2 Predicted to be located in ribosome. WB:WBGene00011708 T11B7.5 Enriched in AVKL; AVKR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011709 T11F9.1 Predicted to be located in membrane. WB:WBGene00011710 T11F9.7 Enriched in RICL; RICR; and body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; pmk-1; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine based on microarray studies. WB:WBGene00011712 T11F9.10 Enriched in AFD; PLM; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011713 htrl-1 Expressed in pharyngeal neurons. Is predicted to encode a protein with the following domains: WlaTC/HtrL glycosyltransferase and Bacterial protein of unknown function (HtrL_YibB). WB:WBGene00011714 T11F9.13 Is affected by several genes including sir-2.1; pgl-1; and glh-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00011715 T11F9.14 Is affected by several genes including clk-1; hpl-2; and drh-3 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including aldicarb; Tunicamycin; and resveratrol based on microarray studies. WB:WBGene00011716 T11F9.19 Is affected by several genes including clk-1; pgl-1; and prg-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00011717 T11G6.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC37A3 (solute carrier family 37 member 3). WB:WBGene00011718 T11G6.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC37A3 (solute carrier family 37 member 3). WB:WBGene00011719 T11G6.4 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC37A3 (solute carrier family 37 member 3). WB:WBGene00011720 T11G6.5 Predicted to enable monooxygenase activity. Predicted to be involved in negative regulation of gene expression, epigenetic. Predicted to be located in nucleoplasm. Is an ortholog of human TASOR2 (transcription activation suppressor family member 2). WB:WBGene00011721 T11G6.7 Enriched in NSM; head mesodermal cell; and in male based on tiling array and RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00011722 rbm-22 Predicted to enable U6 snRNA binding activity and pre-mRNA binding activity. Located in nucleus. Is an ortholog of human RBM22 (RNA binding motif protein 22). WB:WBGene00011723 T12A7.2 Predicted to be located in membrane. WB:WBGene00011724 scl-18 Predicted to be located in extracellular space. Is an ortholog of several human genes including CRISPLD1 (cysteine rich secretory protein LCCL domain containing 1); GLIPR1 (GLI pathogenesis related 1); and PI15 (peptidase inhibitor 15). WB:WBGene00011725 lips-5 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00011726 lpr-2 Predicted to enable retinoid binding activity and retinol transmembrane transporter activity. Predicted to be involved in lipid transport. Predicted to be located in extracellular region. WB:WBGene00011727 T12A7.6 Enriched in body wall muscle cell; head mesodermal cell; and muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Cry5B; levamisole; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00011728 T12A7.7 Enriched in PHA; coelomocyte; head mesodermal cell; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including clk-1; rrf-1; and mex-3 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00011729 set-16 Enables histone H3K4 methyltransferase activity. Involved in programmed cell death and regulation of vulval development. Part of MLL3/4 complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and linker cell. Human ortholog(s) of this gene implicated in several diseases, including Kabuki syndrome; Kleefstra syndrome 2; and carcinoma (multiple). Is an ortholog of human KMT2D (lysine methyltransferase 2D). WB:WBGene00011730 drr-2 Predicted to enable RNA binding activity. Part of polysome. Expressed in several structures, including coelomocyte; excretory canal; neurons; ventral nerve cord; and vulva. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Is an ortholog of human EIF4H (eukaryotic translation initiation factor 4H). WB:WBGene00011731 acbp-5 Predicted to enable fatty-acyl-CoA binding activity. Expressed in intestine and pharynx. Is an ortholog of human ACBD6 (acyl-CoA binding domain containing 6). WB:WBGene00011732 arrd-17 Enables protein phosphatase 2B binding activity. Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Expressed in nervous system. WB:WBGene00011733 T12D8.5 Enriched in MSaaaaapa; head mesodermal cell; intestine; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-six chemicals including hydrogen sulfide; rotenone; and Tunicamycin based on microarray; RNA-seq; and proteomic studies. WB:WBGene00011734 mlc-5 Predicted to enable calcium ion binding activity. Involved in mitotic cytokinesis. Located in actin cytoskeleton. Human ortholog(s) of this gene implicated in congenital myopathy 14; familial atrial fibrillation; and hypertrophic cardiomyopathy 8. Is an ortholog of human MYL4 (myosin light chain 4); MYL6 (myosin light chain 6); and MYL6B (myosin light chain 6B). WB:WBGene00011735 hip-1 Predicted to enable Hsp70 protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Expressed in head and tail. Is an ortholog of human ST13 (ST13 Hsp70 interacting protein) and ST13P5 (ST13, Hsp70 interacting protein pseudogene 5). WB:WBGene00011736 T12D8.9 Expressed in alimentary muscle; body wall musculature; and vulval muscle. WB:WBGene00011737 sqst-1 Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and protein kinase C binding activity. Predicted to be involved in aggrephagy; endosome organization; and mitophagy. Located in cytoplasm. Expressed in several structures, including head; hypodermal cell; muscle cell; tail; and vulva. Human ortholog(s) of this gene implicated in Paget's disease of bone 3; distal myopathy with rimmed vacuoles; and neurodegenerative disease (multiple). Is an ortholog of human SQSTM1 (sequestosome 1). WB:WBGene00011738 T12G3.2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including defense response; receptor signaling pathway via JAK-STAT; and regulation of transcription by RNA polymerase II. WB:WBGene00011739 T12G3.4 Predicted to enable hydrolase activity. Predicted to be involved in biosynthetic process. Predicted to be located in membrane. Is an ortholog of human APMAP (adipocyte plasma membrane associated protein). WB:WBGene00011740 mrpl-51 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrial ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL51 (mitochondrial ribosomal protein L51). WB:WBGene00011741 T12G3.6 Expressed widely. WB:WBGene00011742 tgn-38 Predicted to be located in membrane. Is an ortholog of human C5orf15 (chromosome 5 open reading frame 15) and TGOLN2 (trans-golgi network protein 2). WB:WBGene00011743 T13F2.2 Enables transcription coactivator activity. Involved in RNA polymerase II promoter clearance. Predicted to be located in nucleus. Is an ortholog of human SUB1 (SUB1 regulator of transcription). WB:WBGene00011744 T13F2.4 Enriched in ASER; PLM; and hypodermis based on RNA-seq studies. Is affected by several genes including daf-16; let-60; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including methylmercury hydroxide; manganese chloride; and antimycin based on RNA-seq studies. WB:WBGene00011745 sre-4 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in neurons. WB:WBGene00011746 T13F2.6 Enriched in several structures, including AVJ; Z1.p; germ line; germline precursor cell; and male distal tip cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including manganese chloride; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00011747 sna-2 Expressed in several structures, including germ cell and somatic cell. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011748 T13F2.9 Enriched in several structures, including cholinergic neurons; coelomocyte; intestine; sperm; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including hydrogen sulfide; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00011749 ssp-36 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; D-glucose; and Doxycycline based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00011750 nhr-218 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00011751 T13F3.4 Is affected by several genes including clk-1; prg-1; and mrps-5 based on tiling array and microarray studies. Is affected by Chlorpyrifos and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00011752 fbxa-2 Enriched in several structures, including excretory cell; intestine; male distal tip cell; neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including aldicarb; Alovudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00011753 T13F3.6 Enriched in AFD and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirty-three chemicals including methylmercuric chloride; Mercuric Chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00011754 T13F3.7 Predicted to be located in membrane. WB:WBGene00011755 T13H5.1 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in synaptic membrane adhesion. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Is an ortholog of human PTPRA (protein tyrosine phosphatase receptor type A) and PTPRE (protein tyrosine phosphatase receptor type E). WB:WBGene00011756 ctg-2 Predicted to be located in cytoplasm. Is an ortholog of several human genes including SEC14L2 (SEC14 like lipid binding 2); SEC14L3 (SEC14 like lipid binding 3); and SEC14L4 (SEC14 like lipid binding 4). WB:WBGene00011757 cht-2 Predicted to enable chitin binding activity and hydrolase activity, acting on glycosyl bonds. Predicted to be involved in carbohydrate metabolic process. WB:WBGene00011758 prp-9 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human SF3A3 (splicing factor 3a subunit 3). WB:WBGene00011759 mrps-18B Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS18B (mitochondrial ribosomal protein S18B). WB:WBGene00011760 gldi-7 Predicted to be involved in regulation of sodium ion transport. Predicted to be located in plasma membrane. Is an ortholog of human NKAIN2 (sodium/potassium transporting ATPase interacting 2); NKAIN3 (sodium/potassium transporting ATPase interacting 3); and NKAIN4 (sodium/potassium transporting ATPase interacting 4). WB:WBGene00011761 T13H5.8 Predicted to be located in endomembrane system and membrane. Human ortholog(s) of this gene implicated in carcinoma (multiple) and pulmonary emphysema. Is an ortholog of human CLPTM1L (CLPTM1 like). WB:WBGene00011762 T13H10.2 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00011763 T14B1.1 Expressed in hypodermis; muscle cell; neurons; and ventral nerve cord. WB:WBGene00011765 frpr-17 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00011766 T14C1.2 No description available WB:WBGene00011767 agxt-1 Enables alanine-glyoxylate transaminase activity. Involved in glycine biosynthetic process, by transamination of glyoxylate. Located in mitochondrion. Human ortholog(s) of this gene implicated in primary hyperoxaluria type 1. Is an ortholog of human AGXT (alanine--glyoxylate aminotransferase). WB:WBGene00011768 oac-46 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00011770 T14G8.2 Enriched in PVR; Z1.p; Z4.a; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; mianserin; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00011771 T14G8.3 Predicted to enable adenyl-nucleotide exchange factor activity. Involved in IRE1-mediated unfolded protein response. Predicted to be part of endoplasmic reticulum chaperone complex. Human ortholog(s) of this gene implicated in immunodeficiency 59. Is an ortholog of human HYOU1 (hypoxia up-regulated 1). WB:WBGene00011772 T14G8.4 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercury hydroxide; methylmercuric chloride; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00011773 ttr-53 Predicted to be located in cell surface and extracellular region. WB:WBGene00011774 ttr-54 Predicted to be located in cell surface and extracellular region. WB:WBGene00011775 copg-1 Predicted to enable structural molecule activity. Predicted to be involved in Golgi vesicle transport and cellular localization. Predicted to be located in Golgi membrane; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. Predicted to be part of COPI vesicle coat. Is an ortholog of human COPG1 (COPI coat complex subunit gamma 1) and COPG2 (COPI coat complex subunit gamma 2). WB:WBGene00011776 pigs-1 Predicted to be involved in attachment of GPI anchor to protein. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of GPI-anchor transamidase complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 95. Is an ortholog of human PIGS (phosphatidylinositol glycan anchor biosynthesis class S). WB:WBGene00011777 T14G10.8 Enriched in several structures, including ABalpapaap; ABarappaap; AVK; germ line; and sperm based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; rotenone; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00011778 T15D6.1 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00011779 bgnt-1.7 Is affected by several genes including sir-2.1; clk-1; and drh-3 based on tiling array; microarray; and RNA-seq studies. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A13. Human B4GAT1 enables glucuronosyltransferase activity. Is predicted to encode a protein with the following domain: Glycosyl-transferase for dystroglycan. Is an ortholog of human B4GAT1 (beta-1,4-glucuronyltransferase 1). WB:WBGene00011780 T15D6.5 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. WB:WBGene00011781 glct-3 Predicted to enable galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity. Predicted to be involved in carbohydrate metabolic process and chondroitin sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Used to study propionic acidemia. Human ortholog(s) of this gene implicated in Barrett's esophagus and schizophrenia. Is an ortholog of human B3GAT1 (beta-1,3-glucuronyltransferase 1) and B3GAT2 (beta-1,3-glucuronyltransferase 2). WB:WBGene00011782 T15D6.8 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00011783 T15D6.9 Enriched in intestine based on microarray studies. Is affected by several genes including daf-2; clk-1; and ikb-1 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1647) and Protein of unknown function DUF1647. WB:WBGene00011784 T15D6.10 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00011785 T15D6.11 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00011786 T15D6.12 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00011788 hal-3 Enriched in FLP; germ line; germline precursor cell; intestine; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00011789 T15H9.4 Enriched in intestine based on microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Uncharacterized protein T15H9.4-like. WB:WBGene00011790 T15H9.5 Enriched in several structures, including MSaapaapa; amphid sheath cell; neurons; pharyngeal gland cell; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; D-glucose; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00011791 pap-2 Predicted to enable RNA binding activity; ion binding activity; and poly(A) RNA polymerase activity. Predicted to be involved in mRNA polyadenylation. Predicted to be located in nucleus. Is an ortholog of human PAPOLB (poly(A) polymerase beta). WB:WBGene00011792 T16A9.1 No description available WB:WBGene00011793 T16A9.3 Enriched in several structures, including ABaraapapaa; ABaraapppaa; XXX cell; rectal epithelial cell; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and clk-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including rotenone; Sodium Chloride; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1265; SKP1/BTB/POZ domain superfamily; and Protein of unknown function (DUF1265). WB:WBGene00011794 nep-21 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Expressed in accessory cell; anterior ganglion; lumbar ganglion; motor neurons; and ventral nerve cord. WB:WBGene00011795 T16A9.5 Predicted to be located in membrane. WB:WBGene00011796 T16G1.2 Enriched in several structures, including ALA; hypodermis; interfacial epithelial cell; mechanosensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00011797 T16G1.3 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00011798 T16G1.4 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00011799 T16G1.5 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00011800 T16G1.6 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Expressed in head neurons and intestine. WB:WBGene00011801 T16G1.7 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00011802 T16G1.9 Predicted to enable hydrolase activity. WB:WBGene00011803 T16G12.1 Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Involved in embryo development; regulation of egg-laying behavior; and regulation of meiotic cell cycle process involved in oocyte maturation. Predicted to be located in cytoplasm. WB:WBGene00011804 T16G12.3 Enriched in I5 neuron; cholinergic neurons; germ line; head mesodermal cell; and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011805 T16G12.4 Predicted to be located in membrane. WB:WBGene00011806 ekl-6 Predicted to be involved in protein secretion. Is an ortholog of human TANGO6 (transport and golgi organization 6 homolog). WB:WBGene00011807 T16G12.6 Predicted to enable tRNA binding activity. Predicted to be involved in tRNA re-export from nucleus. Predicted to be located in cytoplasm and nuclear matrix. Predicted to be part of nuclear pore. Is an ortholog of human IPO13 (importin 13). WB:WBGene00011808 T16G12.7 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00011809 T16G12.8 Predicted to be located in membrane. WB:WBGene00011810 T16G12.9 Enriched in Z1.p; Z4.a; gon_male_dtc anterior; gon_male_dtc posterior; and male-specific anatomical entity based on RNA-seq studies. Is affected by several genes including pgl-1; fog-2; and aak-2 based on RNA-seq; microarray; and proteomic studies. Is affected by Alovudine and bortezomib based on RNA-seq studies. WB:WBGene00011811 T16H12.1 Enriched in germ line; germline precursor cell; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including D-glucose; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011812 T16H12.2 Enriched in several structures, including AFD; RIC; RMD; germ line; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; ced-3; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including rotenone; mianserin; and stavudine based on RNA-seq and microarray studies. WB:WBGene00011813 T16H12.3 Enriched in several structures, including B cell; MSpaaapa; germ line; germline precursor cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including lin-4; lin-14; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00011814 gtf-2H2C Predicted to enable zinc ion binding activity. Predicted to be involved in nucleotide-excision repair and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIH holo complex. Is an ortholog of human GTF2H2 (general transcription factor IIH subunit 2); GTF2H2C (GTF2H2 family member C); and GTF2H2C_2. WB:WBGene00011815 spop-1 Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple) and lung adenocarcinoma. Is an ortholog of human SPOPL (speckle type BTB/POZ protein like). WB:WBGene00011816 srt-55 Predicted to be located in membrane. WB:WBGene00011817 T16H12.9 Enriched in excretory cell; intestine; neuronal sheath cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; antimycin; and Cadmium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cystine-knot cytokine. WB:WBGene00011818 srt-57 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by tetrabromobisphenol A based on microarray studies. WB:WBGene00011819 hal-2 Located in nucleoplasm. Expressed in germ cell. WB:WBGene00011820 T18D3.1 Enriched in several structures, including ABplaapaaa; ABplapppapp; ABpraapaaa; AFD; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eight chemicals including D-glucose; iron oxide nanoparticle; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: WD repeat-containing protein 89; WD40/YVTN repeat-like-containing domain superfamily; and WD40-repeat-containing domain superfamily. WB:WBGene00011821 cdf-2 Predicted to enable zinc ion transmembrane transporter activity. Involved in cellular response to zinc ion and zinc ion transmembrane transport. Located in gut granule membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human SLC30A8 (solute carrier family 30 member 8). WB:WBGene00011822 T18D3.5 Predicted to be located in membrane. WB:WBGene00011823 T18D3.6 Enriched in head mesodermal cell; hypodermis; intestine; neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011824 tsct-1 Predicted to be involved in regulation of transcription by RNA polymerase II. Expressed in body wall musculature; nerve ring; and pharyngeal muscle cell. Is an ortholog of human TSC22D3 (TSC22 domain family member 3). WB:WBGene00011826 T18D3.9 Predicted to be involved in cellular response to reactive oxygen species. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2EE and mitochondrial DNA depletion syndrome 6. Is an ortholog of human MPV17 (mitochondrial inner membrane protein MPV17). WB:WBGene00011827 T19A6.1 Predicted to be involved in phospholipid translocation and retrograde transport, endosome to Golgi. Predicted to be located in endosome and trans-Golgi network. Is an ortholog of human SLC66A2 (solute carrier family 66 member 2). WB:WBGene00011828 nepr-1 Involved in regulation of nuclear division. Predicted to be located in cytoplasm and nuclear membrane. Predicted to be part of Nem1-Spo7 phosphatase complex. Is an ortholog of human CNEP1R1 (CTD nuclear envelope phosphatase 1 regulatory subunit 1). WB:WBGene00011829 T19A6.4 Predicted to enable carbohydrate transmembrane transporter activity. Predicted to be involved in carbohydrate transmembrane transport. Predicted to be located in membrane. WB:WBGene00011830 cyp-29A2 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. WB:WBGene00011831 T19B10.2 Expressed in hypodermis. WB:WBGene00011832 bgal-1 Predicted to enable beta-galactosidase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in vacuole. Human ortholog(s) of this gene implicated in GM1 gangliosidosis (multiple) and mucopolysaccharidosis type IVB. Is an ortholog of human GLB1L (galactosidase beta 1 like). WB:WBGene00011833 T19B10.5 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 3 and Charcot-Marie-Tooth disease type 4F. Is an ortholog of human AHNAK2 (AHNAK nucleoprotein 2) and PRX (periaxin). WB:WBGene00011834 dvc-1 Predicted to enable polyubiquitin modification-dependent protein binding activity. Involved in DNA damage response. Located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in Ruijs-Aalfs syndrome. Is an ortholog of human SPRTN (SprT-like N-terminal domain). WB:WBGene00011835 pgap-1 Predicted to enable phosphatidylinositol deacylase activity. Predicted to be involved in GPI anchor metabolic process and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum. Is an ortholog of human PGAP1 (post-GPI attachment to proteins inositol deacylase 1). WB:WBGene00011836 mam-4 Enriched in ABplpaaaaa; ABprpaaaaa; interfacial epithelial cell; and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercury hydroxide; manganese chloride; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Concanavalin A-like lectin/glucanase domain superfamily. WB:WBGene00011837 srsx-33 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of several human genes including OR2M4 (olfactory receptor family 2 subfamily M member 4); OR5H1 (olfactory receptor family 5 subfamily H member 1); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00011838 T19C4.1 Predicted to be located in membrane. WB:WBGene00011839 T19C4.5 Predicted to enable heme binding activity and oxygen binding activity. Expressed in AIYL and AIYR. WB:WBGene00011840 srbc-62 Predicted to be located in membrane. WB:WBGene00011841 scl-25 Predicted to be located in extracellular space. WB:WBGene00011842 T19C9.6 Is affected by rsr-2; smn-1; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine and Sirolimus based on microarray studies. WB:WBGene00011843 T19C9.7 No description available WB:WBGene00011844 T19C9.8 Enriched in several structures, including MSaapaapa; MSpapaapa; cholinergic neurons; coelomocyte; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-seven chemicals including Heme; tryptophan; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00011846 chil-25 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011847 chil-26 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011848 chil-27 Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00011849 T19H5.4 Enriched in ABplapppapp; ABprapppapp; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011850 T20B3.1 Predicted to enable carnitine O-octanoyltransferase activity. Predicted to be located in peroxisome. Is an ortholog of human CROT (carnitine O-octanoyltransferase). WB:WBGene00011851 clec-23 Is affected by several genes including daf-16; clk-1; and smg-2 based on microarray and RNA-seq studies. Is affected by nitroguanidine based on microarray studies. WB:WBGene00011852 clec-26 Enriched in RIH and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; stavudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00011853 clec-40 Predicted to be located in membrane. WB:WBGene00011854 T20B3.14 Enriched in head mesodermal cell and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; eat-2; and lin-39 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011855 clec-183 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array and RNA-seq studies. Is affected by six chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00011856 nspg-7.1 Enriched in germ line; head mesodermal cell; intestine; mechanosensory neurons; and pharyngeal muscle cell based on proteomic; tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including rotenone; mianserin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00011857 coa-4 Enriched in ASER; germ line; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; let-60; and hsf-1 based on microarray and RNA-seq studies. Is affected by paraquat; Cry5B; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00011858 T20D3.5 Predicted to enable NAD transmembrane transporter activity. Predicted to be involved in NAD transmembrane transport. Predicted to be located in mitochondrion. Is an ortholog of human SLC25A51 (solute carrier family 25 member 51) and SLC25A52 (solute carrier family 25 member 52). WB:WBGene00011859 T20D3.6 Predicted to be involved in mitochondrial respirasome assembly. Located in cytoplasm. Is an ortholog of human HIGD2A (HIG1 hypoxia inducible domain family member 2A). WB:WBGene00011860 pigc-1 Predicted to enable glycosyltransferase activity. Located in nucleus. Human ortholog(s) of this gene implicated in glycosylphosphatidylinositol biosynthesis defect 16. Is an ortholog of human PIGC (phosphatidylinositol glycan anchor biosynthesis class C). WB:WBGene00011864 T20F10.2 Predicted to be located in membrane. WB:WBGene00011865 T20F10.4 No description available WB:WBGene00011867 chc-1 Predicted to enable clathrin light chain binding activity. Involved in several processes, including apical protein localization; determination of adult lifespan; and positive regulation of clathrin-dependent endocytosis. Located in cell periphery; clathrin-coated endocytic vesicle; and mitotic spindle. Expressed in coelomocyte; germ line; hyp7 syncytium; hypodermal cell; and pharyngeal cell. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 56. Is an ortholog of human CLTC (clathrin heavy chain) and CLTCL1 (clathrin heavy chain like 1). WB:WBGene00011868 best-18 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). WB:WBGene00011869 dod-6 Involved in pharyngeal gland morphogenesis. WB:WBGene00011870 T20G5.8 Enriched in several structures, including ABalpapppa; ABaraapapaa; pharyngeal cell; rectal epithelial cell; and rectum based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by fourteen chemicals including rotenone; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00011871 T20G5.9 Predicted to enable RNA binding activity. Predicted to be involved in exon-exon junction complex disassembly. Predicted to be located in cytoplasm. Predicted to be part of exon-exon junction complex. Is an ortholog of human PYM1 (PYM homolog 1, exon junction complex associated factor). WB:WBGene00011872 blos-1 Involved in endosomal transport. Predicted to be located in cytosol; mitochondrial intermembrane space; and mitochondrial matrix. Predicted to be part of BLOC-1 complex. Expressed in excretory cell; intestine; and nervous system. Is an ortholog of human BLOC1S1 (biogenesis of lysosomal organelles complex 1 subunit 1). WB:WBGene00011873 T20G5.12 Enriched in ABalaaaarl; ABalaaaarr; ABplpappaa; coelomocyte; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by fourteen chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00011874 T20G5.13 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABplpappaa; FLP; and excretory cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including sucrose; stearic acid; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00011875 cox-14 Predicted to be located in membrane. WB:WBGene00011876 srz-6 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00011877 T21B4.3 Enriched in IL socket cell; arc ant V; hyp3; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by methylmercuric chloride; Colistin; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00011878 ador-1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in asthma; hypertension; and obesity. Is an ortholog of several human genes including ADORA1 (adenosine A1 receptor); ADORA2A (adenosine A2a receptor); and ADORA2B (adenosine A2b receptor). WB:WBGene00011879 pho-7 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J. Is an ortholog of human ACP2 (acid phosphatase 2, lysosomal) and ACP4 (acid phosphatase 4). WB:WBGene00011880 T21B6.3 Enriched in muscle cell based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including 1-methylnicotinamide; bisphenol A; and Zidovudine based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; PAN/Apple domain; Thrombospondin type 1 domain; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00011882 nstp-9 Predicted to enable GDP-fucose transmembrane transporter activity and antiporter activity. Predicted to be involved in GDP-fucose import into Golgi lumen. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIc. Is an ortholog of human SLC35C1 (solute carrier family 35 member C1). WB:WBGene00011883 mrpl-50 Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL50 (mitochondrial ribosomal protein L50). WB:WBGene00011884 enol-1 Predicted to enable phosphopyruvate hydratase activity. Predicted to be involved in glycolytic process. Predicted to be located in cytoplasm. Predicted to be part of phosphopyruvate hydratase complex. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; migraine without aura; neuroendocrine carcinoma; and prostate cancer. Is an ortholog of human ENO2 (enolase 2). WB:WBGene00011885 T21B10.3 Enriched in germ line; muscle cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; let-60; and daf-12 based on RNA-seq; tiling array; proteomic; and microarray studies. Is affected by seven chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00011886 T21B10.4 Predicted to be located in membrane. WB:WBGene00011887 set-17 Enables histone H3K4 methyltransferase activity. Predicted to be involved in chromatin remodeling and methylation. Predicted to be located in nucleus. Expressed in several structures, including body wall musculature; excretory cell; intestine; primary spermatocyte; and vulval muscle. Is an ortholog of human PRDM7 (PR/SET domain 7). WB:WBGene00011888 cutl-15 Predicted to be located in membrane. WB:WBGene00011890 mics-1 Predicted to be located in membrane. Is an ortholog of human SYNJ2BP (synaptojanin 2 binding protein). WB:WBGene00011891 del-6 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00011892 erh-1 Enables identical protein binding activity. Is an ortholog of human ERH (ERH mRNA splicing and mitosis factor). WB:WBGene00011893 T21C9.6 Predicted to enable ATP binding activity and kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00011894 ttr-23 Predicted to be located in cell surface and extracellular region. WB:WBGene00011895 T21C9.9 Enriched in hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including 1-methylnicotinamide; nicotinic acid; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00011896 T21C9.11 Predicted to be located in membrane. WB:WBGene00011897 scpl-4 Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 9. Is an ortholog of human TIMM50 (translocase of inner mitochondrial membrane 50). WB:WBGene00011898 T21C9.13 Predicted to be located in membrane. Expressed in germ line. WB:WBGene00011899 nlp-68 Predicted to be located in extracellular region. WB:WBGene00011900 T21C12.4 Enriched in NSM; body wall muscle cell; hypodermis; and in male based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; rotenone; and stavudine based on microarray and RNA-seq studies. WB:WBGene00011902 T21E8.4 Enriched in Z1; Z4; coelomocyte; intestine; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; hpl-2; and spr-5 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00011903 T21E8.5 Enriched in PHB; intestine; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and dpy-21 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00011904 hlb-1 Involved in several processes, including neuromuscular junction development; positive regulation of locomotion; and regulation of pharyngeal pumping. Predicted to be located in presynaptic active zone. Is an ortholog of human PPFIBP1 (PPFIA binding protein 1) and PPFIBP2 (PPFIA binding protein 2). WB:WBGene00011906 hsp-12.1 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Located in striated muscle dense body. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease axonal type 2F; cataract (multiple); and myofibrillar myopathy (multiple). Is an ortholog of human CRYAA (crystallin alpha A); CRYAB (crystallin alpha B); and HSPB6 (heat shock protein family B (small) member 6). WB:WBGene00011908 pash-1 Predicted to enable double-stranded RNA binding activity and primary miRNA binding activity. Involved in primary miRNA processing and regulation of developmental process. Predicted to be part of microprocessor complex. Expressed in head; hypodermis; intestine; marginal cell; and pharyngeal muscle cell. Used to study chromosome 22q11.2 deletion syndrome, distal. Is an ortholog of human DGCR8 (DGCR8 microprocessor complex subunit). WB:WBGene00011909 T22A3.6 Enriched in mc1DL; mc1DR; mc1V; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and pie-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including methylmercuric chloride; Tunicamycin; and antimycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Kringle domain; Kringle-like fold; Kringle superfamily; and Kringle. WB:WBGene00011910 alg-3 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Involved in spermatogenesis. Located in P granule. Expressed in germ line. WB:WBGene00011911 T22B3.3 Predicted to be located in cytoskeleton. WB:WBGene00011912 T22C1.1 Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Is an ortholog of human UBR7 (ubiquitin protein ligase E3 component n-recognin 7). WB:WBGene00011913 glb-26 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Located in membrane and nuclear lamina. Expressed in anal depressor muscle; head mesodermal cell; intestinal muscle; and in male. WB:WBGene00011914 pigu-1 Predicted to be involved in attachment of GPI anchor to protein. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of GPI-anchor transamidase complex. Is an ortholog of human PIGU (phosphatidylinositol glycan anchor biosynthesis class U). WB:WBGene00011915 ctf-8 Predicted to be involved in mitotic sister chromatid cohesion. Predicted to be part of Ctf18 RFC-like complex. Is an ortholog of human CHTF8 (chromosome transmission fidelity factor 8). WB:WBGene00011916 T22C1.5 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalpapaap; AFD; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including manganese chloride; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00011917 T22C1.6 Predicted to enable syntaxin binding activity. Located in endoplasmic reticulum. Expressed in head and tail. Is an ortholog of human TXLNA (taxilin alpha); TXLNB (taxilin beta); and TXLNG (taxilin gamma). WB:WBGene00011918 T22C1.8 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00011919 T22C1.9 Predicted to be located in membrane. WB:WBGene00011920 T22C1.11 Enriched in interfacial epithelial cell; intestine; neurons; pharyngeal cell; and rect_D based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; RNA-seq; and tiling array studies. Is affected by ten chemicals including levamisole; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00011921 T22C1.12 Enriched in g1AL; g1AR; g2L; g2R; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and lin-35 based on tiling array and RNA-seq studies. Is affected by allantoin; Sirolimus; and metformin based on RNA-seq studies. WB:WBGene00011922 T22C8.1 Predicted to be located in membrane. WB:WBGene00011923 chhy-1 Enables hexosaminidase activity. Involved in chondroitin sulfate catabolic process. Expressed in PLML; PLMR; head; intestinal cell; and vulva. Human ortholog(s) of this gene implicated in mucopolysaccharidosis IX. Is an ortholog of human HYAL2 (hyaluronidase 2). WB:WBGene00011924 T22C8.3 Enriched in several structures, including ABalaapppp; ABalapaapp; ABplpaappa; ABprpaappa; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including stavudine; Zidovudine; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type; Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and Phosphorylation site. WB:WBGene00011925 T22C8.4 Enriched in several structures, including MSpppaaa; head mesodermal cell; male distal tip cell; rectal epithelial cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including mianserin; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2 superfamily. WB:WBGene00011926 sptf-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in canonical Wnt signaling pathway. Expressed in head neurons and intestine. Is an ortholog of human SP5 (Sp5 transcription factor). WB:WBGene00011927 T22C8.6 Enriched in hypodermis and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011928 cutl-12 Predicted to be located in membrane. WB:WBGene00011929 T22G5.1 Predicted to enable glycerophosphodiester phosphodiesterase activity. Predicted to be involved in N-acylethanolamine metabolic process; ethanolamine metabolic process; and phospholipid metabolic process. Predicted to be located in plasma membrane. Is an ortholog of human GDE1 (glycerophosphodiester phosphodiesterase 1). WB:WBGene00011930 T22G5.3 Enriched in several structures, including AVJ; FLP; MSpaaapa; body wall muscle cell; and intestine based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; Zidovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00011931 srsx-19 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00011932 sptl-3 Predicted to enable serine C-palmitoyltransferase activity. Predicted to be involved in ceramide biosynthetic process and sphingosine biosynthetic process. Predicted to be part of serine C-palmitoyltransferase complex. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1C. Is an ortholog of human SPTLC2 (serine palmitoyltransferase long chain base subunit 2) and SPTLC3 (serine palmitoyltransferase long chain base subunit 3). WB:WBGene00011933 oac-47 Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including cadmium; fluoranthene; and Chlorpyrifos based on microarray studies. WB:WBGene00011934 T22H2.4 Enriched in body wall musculature; muscle cell; and rectal muscle based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Rifampin; Sirolimus; and Atrazine based on RNA-seq and microarray studies. WB:WBGene00011935 scrm-1 Enables phospholipid scramblase activity. Involved in phosphatidylserine exposure on apoptotic cell surface. Located in plasma membrane. Expressed in several structures, including germ line. Is an ortholog of several human genes including PLSCR2 (phospholipid scramblase 2); PLSCR3 (phospholipid scramblase 3); and PLSCR4 (phospholipid scramblase 4). WB:WBGene00011936 pgrn-1 Predicted to be located in extracellular region. Expressed in coelomocyte; neurons; and pseudocoelom. Used to study frontotemporal dementia. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Grn-related frontotemporal lobar degeneration with Tdp43 inclusions; and multiple sclerosis (multiple). Is an ortholog of human GRN (granulin precursor). WB:WBGene00011937 ilc-17.1 Predicted to enable cytokine activity. Involved in positive regulation of locomotion and response to oxygen levels. Located in extracellular region. WB:WBGene00011938 alh-13 Predicted to enable glutamate-5-semialdehyde dehydrogenase activity. Predicted to be involved in L-proline biosynthetic process and phosphorylation. Located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including cutis laxa (multiple); enterocele; and hereditary spastic paraplegia (multiple). Is an ortholog of human ALDH18A1 (aldehyde dehydrogenase 18 family member A1). WB:WBGene00011939 prmt-9 Predicted to enable protein-arginine omega-N monomethyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human PRMT9 (protein arginine methyltransferase 9). WB:WBGene00011940 T23B5.3 Enriched in several structures, including XXX cell; enteric muscle; germ line; head mesodermal cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on RNA-seq; microarray; and proteomic studies. Is affected by five chemicals including hydrogen sulfide; Zidovudine; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. WB:WBGene00011941 T23B5.4 Predicted to enable translation release factor activity. Predicted to be involved in translational termination. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 7 and hereditary spastic paraplegia 55. Is an ortholog of human MTRFR (mitochondrial translation release factor in rescue). WB:WBGene00011942 T23D5.3 Predicted to be located in membrane. WB:WBGene00011943 T23D5.8 Predicted to be located in membrane. WB:WBGene00011944 T23D8.3 Predicted to be involved in ribosomal small subunit biogenesis and ribosomal small subunit export from nucleus. Predicted to be located in cytosol and nucleus. Predicted to be part of preribosome, small subunit precursor. Is an ortholog of human LTV1 (LTV1 ribosome biogenesis factor). WB:WBGene00011945 alg-5 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. Located in P granule. WB:WBGene00011947 T23F1.3 Enriched in NSM based on tiling array studies. Is affected by qui-1 based on RNA-seq studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00011948 rocf-1 Predicted to be located in membrane. WB:WBGene00011949 idpp-7 Enriched in arcade cell; cholinergic neurons; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including D-glucose; Neurotoxins; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00011950 T23F6.2 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by five chemicals including methylmercury hydroxide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00011951 T23F6.3 Predicted to enable metal ion binding activity. WB:WBGene00011952 T23F6.5 Enriched in several structures, including anterior ganglion (ant); anterior hypodermis; excretory system; mechanosensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including methylmercury hydroxide; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00011953 ppm-2 Enables ubiquitin protein ligase binding activity. Involved in negative regulation of axon extension and positive regulation of synapse assembly. Located in presynaptic active zone. Expressed in mechanosensory neurons; motor neurons; muscle cell; nerve ring neurons; and pharynx. WB:WBGene00011954 T23F11.2 Enriched in several structures, including AVK; DD neuron; germ line; pharyngeal-intestinal valve cell; and sperm based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00011955 cdka-1 Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity and protein kinase binding activity. Involved in GABAergic synaptic transmission; regulation of cellular localization; and synaptic vesicle transport. Predicted to be located in cytoplasm and growth cone. Predicted to be part of protein kinase 5 complex. Used to study epilepsy and lissencephaly. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1) and CDK5R2 (cyclin dependent kinase 5 regulatory subunit 2). WB:WBGene00011956 T23F11.4 Enriched in several structures, including G2; W cell; accessory cell; germ line; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including hydrogen sulfide; Doxycycline; and paraquat based on microarray and RNA-seq studies. WB:WBGene00011957 T23F11.6 Enriched in several structures, including anterior hypodermis; arc ant V; enteric muscle; g2; and lateral ganglion based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00011958 T23G4.2 Predicted to enable ATP-dependent peptidase activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00011959 nyn-1 Involved in siRNA processing. WB:WBGene00011960 oac-48 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00011961 srlf-26 Enriched in I5 neuron; body wall muscle cell; coelomocyte; germline precursor cell; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including let-60; rrf-3; and tph-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00011962 T23G5.2 Predicted to be located in cytoplasm. Is an ortholog of human SEC14L5 (SEC14 like lipid binding 5). WB:WBGene00011963 T23G5.3 Predicted to be involved in protein homooligomerization. WB:WBGene00011964 saeg-2 Predicted to enable DNA binding activity and nucleosome binding activity. Located in nucleus. Is an ortholog of human DNTTIP1 (deoxynucleotidyltransferase terminal interacting protein 1). WB:WBGene00011965 T23G7.2 Predicted to enable hydrolase activity. Predicted to be located in membrane. Is an ortholog of human TMPPE (transmembrane protein with metallophosphoesterase domain). WB:WBGene00011966 T23G7.3 Predicted to enable telomerase inhibitor activity. Predicted to be located in nucleolus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1). WB:WBGene00011967 pir-1 Enables inorganic triphosphate phosphatase activity. Predicted to be involved in dephosphorylation and regulatory ncRNA-mediated gene silencing. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human DUSP11 (dual specificity phosphatase 11). WB:WBGene00011968 T23G11.1 Predicted to be located in membrane. WB:WBGene00011969 T23G11.4 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human C9orf78 (chromosome 9 open reading frame 78). WB:WBGene00011970 rlbp-1 Predicted to enable GTPase activator activity and small GTPase binding activity. Predicted to be involved in small GTPase mediated signal transduction. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma and urinary bladder cancer. Is an ortholog of human RALBP1 (ralA binding protein 1). WB:WBGene00011971 lron-9 Predicted to be located in membrane. Expressed in head neurons; muscle cell; seam cell; and ventral cord neurons. Is an ortholog of human LRG1 (leucine rich alpha-2-glycoprotein 1). WB:WBGene00011972 T23G11.7 Predicted to enable SNARE binding activity. Predicted to be involved in SNARE complex assembly. Predicted to be located in endosome and lytic vacuole. Is an ortholog of human UVRAG (UV radiation resistance associated). WB:WBGene00011973 T23G11.10 Predicted to be located in membrane. WB:WBGene00011974 xbx-5 Predicted to be located in membrane. Expressed in gonad and neurons. WB:WBGene00011975 golg-5 Predicted to enable protein homodimerization activity. Predicted to be involved in Golgi organization and retrograde transport, vesicle recycling within Golgi. Predicted to be located in Golgi cisterna and Golgi membrane. Is an ortholog of human GOLGA5 (golgin A5). WB:WBGene00011976 chmp-7 Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and vesicle budding from membrane. Predicted to be located in cytoplasmic side of plasma membrane and multivesicular body. Predicted to be part of ESCRT III complex. Is an ortholog of human CHMP7 (charged multivesicular body protein 7). WB:WBGene00011977 T24B8.3 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppappa; ABalpppappp; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; bisphenol A; and bisphenol S based on RNA-seq; microarray; and proteomic studies. WB:WBGene00011978 T24B8.4 Predicted to enable actin binding activity. Predicted to be involved in positive regulation of actin filament polymerization. WB:WBGene00011979 sysm-1 Involved in antibacterial innate immune response. Expressed in intestine. WB:WBGene00011980 T24B8.7 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in Y-linked spermatogenic failure 2; female-restricted syndromic X-linked intellectual disability 99; and non-syndromic X-linked intellectual disability 99. Is an ortholog of human USP24 (ubiquitin specific peptidase 24). WB:WBGene00011981 enri-2 Enriched in several structures, including AVG; RIM; command interneuron; germ line; and germline precursor cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011982 T24C2.3 Enriched in ABaraapapp and ABaraapppp based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011983 fbxa-81 Enriched in several structures, including ABalapapapa; ABalapppapa; ABarpapaapp; ABplaaaaapp; and amphid neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00011984 T24C2.5 Enriched in SIB; dopaminergic neurons; excretory cell; head mesodermal cell; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including rotenone; D-glucopyranose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00011985 T24D1.2 Predicted to enable metal ion binding activity. WB:WBGene00011986 T24D1.3 Predicted to enable metal ion binding activity. WB:WBGene00011988 har-2 Predicted to enable metal ion binding activity. WB:WBGene00011989 T24D5.1 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00011990 T24D5.2 Enriched in Y cell and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011991 T24D5.3 Enriched in several structures, including MSpppaaa; Z1.p; head mesodermal cell; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; mex-1; and hda-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00011992 T24D5.4 Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human LATS1 (large tumor suppressor kinase 1) and LATS2 (large tumor suppressor kinase 2). WB:WBGene00011993 T24D5.5 Is affected by several genes including daf-2; sir-2.1; and lin-35 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00011994 samp-1 Predicted to enable actin filament binding activity and lamin binding activity. Involved in embryo development and nuclear migration along microtubule. Located in nuclear envelope. Is an ortholog of human TMEM201 (transmembrane protein 201). WB:WBGene00011995 rsf-1 Enables small GTPase binding activity. Involved in several processes, including organelle organization; positive regulation of response to oxidative stress; and regulation of vulval development. Predicted to be located in cytoplasm and microtubule. Expressed in pharynx and vulva. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); reproductive organ cancer (multiple); and urinary bladder cancer. Is an ortholog of human RASSF1 (Ras association domain family member 1) and RASSF5 (Ras association domain family member 5). WB:WBGene00011996 T24F1.4 Predicted to be located in membrane. WB:WBGene00011997 nlp-51 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00011999 T24F1.7 Predicted to be located in membrane. WB:WBGene00012000 T24H10.1 Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of human TCEA1 (transcription elongation factor A1); TCEA2 (transcription elongation factor A2); and TCEA3 (transcription elongation factor A3). WB:WBGene00012002 T24H10.4 Predicted to be located in nuclear outer membrane. Human ortholog(s) of this gene implicated in craniotubular dysplasia Ikegawa type. Is an ortholog of human TMEM53 (transmembrane protein 53). WB:WBGene00012003 T24H10.5 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including tryptophan; Sodium Chloride; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00012004 dyrb-1 Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Located in several cellular components, including cell cortex; microtubule cytoskeleton; and perinuclear region of cytoplasm. Expressed in ciliated neurons and intestine. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human DYNLRB1 (dynein light chain roadblock-type 1) and DYNLRB2 (dynein light chain roadblock-type 2). WB:WBGene00012005 jun-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of RNA splicing; and response to starvation. Located in nucleus. Expressed in several structures, including excretory cell; hermaphrodite gonad; nervous system; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and lymphoma (multiple). Is an ortholog of human JUN (Jun proto-oncogene, AP-1 transcription factor subunit); JUNB (JunB proto-oncogene, AP-1 transcription factor subunit); and JUND (JunD proto-oncogene, AP-1 transcription factor subunit). WB:WBGene00012007 T25B9.1 Predicted to enable glycine C-acetyltransferase activity; pyridoxal phosphate binding activity; and transaminase activity. Predicted to be involved in biosynthetic process and threonine catabolic process. Predicted to be located in mitochondrion. Is an ortholog of human GCAT (glycine C-acetyltransferase). WB:WBGene00012008 T25B9.2 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00012009 T25B9.3 Enriched in several structures, including cholinergic neurons; head mesodermal cell; head neurons; rectal epithelial cell; and rectum based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; pmk-1; and lin-35 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; Sirolimus; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00012010 T25B9.4 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00012011 T25B9.5 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00012012 T25B9.6 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00012013 ugt-54 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00012014 T25B9.8 Enriched in several structures, including ABalaaaarl; ABalaaaarr; AFD; AVA; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00012015 T25B9.9 Predicted to enable NADP binding activity and phosphogluconate dehydrogenase (decarboxylating) activity. Involved in defense response to Gram-negative bacterium and negative regulation of gene expression. Predicted to be located in cytosol. Is an ortholog of human PGD (phosphogluconate dehydrogenase). WB:WBGene00012016 inpp-1 Predicted to enable phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation and positive regulation of flagellated sperm motility. Located in cytoplasm. Human ortholog(s) of this gene implicated in congenital muscular dystrophy with cataracts and intellectual disability. Is an ortholog of human INPP5K (inositol polyphosphate-5-phosphatase K). WB:WBGene00012017 shpk-1 Predicted to enable sedoheptulokinase activity. Predicted to be involved in glycerol metabolic process and phosphorylation. Predicted to be located in cytosol. Is an ortholog of human SHPK (sedoheptulokinase). WB:WBGene00012018 T25C12.3 Enriched in AFD; germ line; head mesodermal cell; intestine; and pharyngeal muscle cell based on proteomic; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; proteomic; and RNA-seq studies. Is affected by fourteen chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; C-type lectin-like; von Willebrand factor A-like domain superfamily; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; MD domain; and EGF-like domain. WB:WBGene00012019 dkf-2 Enables protein homodimerization activity and protein serine/threonine kinase activity. Involved in defense response to bacterium; determination of adult lifespan; and signal transduction. Acts upstream of with a negative effect on protein import into nucleus. Located in cytoplasmic side of plasma membrane and cytosol. Part of serine/threonine protein kinase complex. Expressed in AVF; NSM; head neurons; lumbar neurons; and spermathecal-uterine junction. Human ortholog(s) of this gene implicated in congenital heart disease. Is an ortholog of human PRKD1 (protein kinase D1); PRKD2 (protein kinase D2); and PRKD3 (protein kinase D3). WB:WBGene00012020 gyg-2 Predicted to enable glycosyltransferase activity. Predicted to be located in cytoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in glycogen storage disease XV. Is an ortholog of human GYG1 (glycogenin 1). WB:WBGene00012021 T25E12.6 Enriched in several structures, including ABalaapppa; ABalapaaaa; body wall muscle cell; ciliated neurons; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; mianserin; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00012022 clec-39 Predicted to be located in membrane. WB:WBGene00012023 clec-34 Predicted to be located in membrane. WB:WBGene00012024 clec-29 Predicted to be located in membrane. WB:WBGene00012025 clec-38 Predicted to enable carbohydrate binding activity. Involved in several processes, including axon guidance; presynapse assembly; and regulation of neuron projection development. Predicted to be located in membrane. Expressed in PLML; PLMR; head neurons; intestine; and ventral cord neurons. WB:WBGene00012026 srz-100 Predicted to be located in membrane. WB:WBGene00012027 fbxa-127 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on RNA-seq; tiling array; and microarray studies. Is affected by nineteen chemicals including methylmercury hydroxide; D-glucopyranose; and sodium arsenite based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00012028 srz-99 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00012029 T25G3.1 Enriched in AFD; germ line; and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; age-1; and let-7 based on microarray; proteomic; and RNA-seq studies. Is affected by six chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4604; Uncharacterized protein KIAA1143-like; and Domain of unknown function (DUF4604). Is an ortholog of human KIAA1143 (KIAA1143). WB:WBGene00012030 T25G3.3 Predicted to enable ribosomal large subunit binding activity. Predicted to be involved in ribosomal large subunit export from nucleus. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human NMD3 (NMD3 ribosome export adaptor). WB:WBGene00012031 gpdh-3 Predicted to enable calcium ion binding activity and sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity. Predicted to be involved in glycerol catabolic process and glycerol-3-phosphate metabolic process. Predicted to be located in mitochondrion. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human GPD2 (glycerol-3-phosphate dehydrogenase 2). WB:WBGene00012032 T26C5.2 Enriched in OLL; PVD; SAA; hypodermis; and intestine based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-five chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00012033 T26C5.3 Predicted to enable acetyl-CoA transmembrane transporter activity. Predicted to be involved in acetyl-CoA transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 42. Is an ortholog of human SLC33A1 (solute carrier family 33 member 1). WB:WBGene00012034 T26C5.4 Enriched in arc ant V; hypodermis; intestine; and neurons based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012035 T26C5.5 Enriched in coelomocyte; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00012036 clec-103 Enriched in neurons and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00012037 T26E3.4 Predicted to be involved in cytoplasmic translation. Predicted to be part of polysome. Expressed in several structures, including intestine; neurons; pseudocoelom; and tail hypodermis. Is an ortholog of human RWDD1 (RWD domain containing 1). WB:WBGene00012038 T26E3.5 Enriched in AVK; DVA; g2L; g2R; and marginal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00012039 T26E3.6 Involved in regulation of protein deneddylation. Located in cytoplasm and nucleus. WB:WBGene00012040 T26E3.7 Predicted to enable ATP binding activity and proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in monoatomic ion transport and proton motive force-driven ATP synthesis. Predicted to be located in membrane. Predicted to be part of proton-transporting ATP synthase complex, catalytic core F(1). WB:WBGene00012041 T26E3.8 Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00012042 T26E3.10 Predicted to be located in membrane. WB:WBGene00012043 irld-52 Predicted to be located in membrane. WB:WBGene00012044 T26E4.2 Enriched in g1AL; g1AR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including sir-2.1; lin-15B; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies. WB:WBGene00012045 T26E4.3 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00012046 T26E4.4 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. Expressed in hyp7 syncytium. WB:WBGene00012047 T26E4.5 Is affected by several genes including sir-2.1; ain-1; and smg-2 based on microarray; tiling array; and RNA-seq studies. WB:WBGene00012048 srxa-17 Is affected by clk-1 and sir-2.1 based on microarray studies. Is affected by Chlorpyrifos and Diazinon based on microarray studies. WB:WBGene00012049 T26E4.7 Is affected by let-60 based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function, DUF273; Protein of unknown function DUF273; and Nucleotide-diphospho-sugar transferases. WB:WBGene00012050 nhr-223 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00012051 T26E4.9 Enriched in PVP; g2; rect_D; and rectal epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including sir-2.1; mex-1; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00012052 T26E4.10 Enriched in g2L and g2R based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and prg-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including methylmercuric chloride; Atrazine; and fluoranthene based on microarray studies. WB:WBGene00012053 srbc-74 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol and Diazinon based on microarray studies. WB:WBGene00012054 srsx-38 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in PVT and neurons. Is an ortholog of several human genes including OR2M4 (olfactory receptor family 2 subfamily M member 4); OR5H1 (olfactory receptor family 5 subfamily H member 1); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00012055 srsx-36 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of several human genes including OR2M4 (olfactory receptor family 2 subfamily M member 4); OR5H1 (olfactory receptor family 5 subfamily H member 1); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00012056 nhr-285 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00012057 T26F2.1 Predicted to enable chitinase activity. Predicted to be involved in cell wall macromolecule catabolic process and chitin catabolic process. WB:WBGene00012058 T26F2.2 Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00012059 T26G10.1 Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleus. Is an ortholog of human DDX47 (DEAD-box helicase 47). WB:WBGene00012060 T26G10.3 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. WB:WBGene00012061 T26G10.4 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; hda-1; and set-2 based on microarray and RNA-seq studies. Is affected by resveratrol and adsorbable organic bromine compound based on microarray studies. WB:WBGene00012062 T26G10.5 Enriched in neurons based on tiling array; single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including aldicarb; rotenone; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00012063 fbxb-1 Enriched in several structures, including ABplaapaaa; ABplaapapa; ABplpappaa; ABpraapaaa; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; mianserin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00012064 fbxb-115 Predicted to be located in membrane. WB:WBGene00012065 fbxb-2 Enriched in ABplaapaaa; ABpraapaaa; and accessory cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including mianserin; allantoin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00012066 fbxb-116 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including methylmercuric chloride; rotenone; and indole based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00012067 sqst-3 Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and protein kinase C binding activity. Predicted to be involved in aggrephagy; endosome organization; and mitophagy. Predicted to be located in aggresome and amphisome. WB:WBGene00012068 oac-49 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00012069 T26H5.4 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and elt-2 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; Tunicamycin; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00012070 T26H5.8 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00012071 T26H8.1 No description available WB:WBGene00012072 T26H8.4 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00012073 cpd-2 Predicted to enable metallocarboxypeptidase activity. Involved in regulation of muscle contraction. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in carboxypeptidase N deficiency; morbid obesity; and type 2 diabetes mellitus. Is an ortholog of human CPE (carboxypeptidase E); CPM (carboxypeptidase M); and CPN1 (carboxypeptidase N subunit 1). WB:WBGene00012074 T27A8.2 Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head muscle; head neurons; pharyngeal neurons; somatic nervous system; and tail. WB:WBGene00012075 T27A8.3 Predicted to enable aminopeptidase activity and metalloexopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human METAP2 (methionyl aminopeptidase 2). WB:WBGene00012077 T27A8.5 Enriched in AVK based on RNA-seq studies. Is affected by several genes including sir-2.1; hpl-2; and set-2 based on RNA-seq; tiling array; and microarray studies. Is affected by six chemicals including cadmium; Diazinon; and dibromoacetic acid based on microarray studies. WB:WBGene00012078 srz-50 Is affected by clk-1 based on microarray studies. Is affected by Progesterone and Sirolimus based on microarray studies. WB:WBGene00012079 T27C5.6 Is affected by clk-1 and sir-2.1 based on microarray studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00012080 clec-244 Enriched in NSM based on tiling array studies. Is affected by clk-1 and ints-2 based on microarray and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies. WB:WBGene00012081 T27C5.8 Predicted to be located in membrane. WB:WBGene00012082 T27C5.9 No description available WB:WBGene00012083 T27C5.10 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00012084 npr-15 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in amphid neurons; head neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including AGTR1 (angiotensin II receptor type 1); AGTR2 (angiotensin II receptor type 2); and APLNR (apelin receptor). WB:WBGene00012085 T27D12.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00012086 clec-144 Enriched in ABplpaaaaa; ABprpaaaaa; and nerve ring neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Tunicamycin; allantoin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00012087 T27E7.1 Enriched in germ line; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-nine chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00012088 T27E7.3 Predicted to be located in membrane. WB:WBGene00012089 T27E7.4 Predicted to be located in membrane. WB:WBGene00012090 T27E7.5 Predicted to be located in membrane. WB:WBGene00012091 pals-29 Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including skn-1; elt-2; and sek-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Mercuric Chloride; and nanoparticle based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012092 T27E7.7 No description available WB:WBGene00012093 T27E7.9 Predicted to be located in membrane. WB:WBGene00012094 T27E9.2 Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency. Is an ortholog of human UQCRH (ubiquinol-cytochrome c reductase hinge protein) and UQCRHL (ubiquinol-cytochrome c reductase hinge protein like). WB:WBGene00012095 pssy-2 Predicted to enable L-serine-phosphatidylethanolamine phosphatidyltransferase activity. Predicted to be involved in phosphatidylserine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Lenz-Majewski hyperostotic dwarfism. Is an ortholog of human PTDSS1 (phosphatidylserine synthase 1). WB:WBGene00012096 T27E9.6 Enriched in ABalaaaarl; ABalaaaarr; AFD; marginal cell; and neuronal sheath cell based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; Mercuric Chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00012097 abcf-2 Predicted to enable ATP binding activity. Expressed in head. Is an ortholog of human ABCF2 (ATP binding cassette subfamily F member 2) and ABCF2-H2BK1 (ABCF2-H2BK1 readthrough). WB:WBGene00012098 fbxb-86 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Alovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00012099 acc-4 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Predicted to be part of chloride channel complex. Expressed in neurons. WB:WBGene00012100 sipa-1 Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in cataract 45. Is an ortholog of several human genes including SIPA1 (signal-induced proliferation-associated 1); SIPA1L1 (signal induced proliferation associated 1 like 1); and SIPA1L3 (signal induced proliferation associated 1 like 3). WB:WBGene00012101 zip-10 Enables core promoter sequence-specific DNA binding activity. Involved in regulation of gene expression. Located in nucleus. Expressed in neurons. WB:WBGene00012102 T27F6.1 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00012103 clec-12 Enriched in several structures, including ABalpppapa; anal sphincter muscle; body wall muscle cell from C lineage; head mesodermal cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by nineteen chemicals including rotenone; D-glucose; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00012104 sygl-1 Expressed in germ cell; germ line; and gonad. WB:WBGene00012105 T27F6.6 Predicted to enable sphingomyelin phosphodiesterase activity. Predicted to be involved in ceramide biosynthetic process; sphingolipid catabolic process; and sphingomyelin metabolic process. Predicted to be located in caveola and endoplasmic reticulum. Is an ortholog of human SMPD2 (sphingomyelin phosphodiesterase 2). WB:WBGene00012106 T27F6.7 Predicted to be located in membrane. WB:WBGene00012107 T27F6.8 Enriched in germline precursor cell; hypodermis; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including rotenone; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00012108 T28A8.2 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00012109 T28A8.3 Enriched in several structures, including I5 neuron; cholinergic neurons; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00012110 T28A8.4 Enriched in body wall musculature; germ line; germline precursor cell; and hypodermis based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twelve chemicals including manganese chloride; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00012111 T28A8.5 Enriched in OLL; PVD; germ line; and germline precursor cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including rotenone; manganese chloride; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00012112 T28A8.6 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABprpaaapa; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including manganese chloride; Zidovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00012113 T28B8.1 Expressed in head muscle; neurons; pharyngeal muscle cell; and vulval muscle. WB:WBGene00012114 T28B8.3 Predicted to enable lysine-acetylated histone binding activity; peptidase activator activity; and proteasome binding activity. Predicted to be involved in proteasomal ubiquitin-independent protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of proteasome complex. WB:WBGene00012115 T28B8.4 Predicted to enable lysine-acetylated histone binding activity; peptidase activator activity; and proteasome binding activity. Predicted to be involved in proteasomal ubiquitin-independent protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of proteasome complex. WB:WBGene00012116 del-4 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Expressed in ganglia and neurons. Human ortholog(s) of this gene implicated in Liddle syndrome; bronchiectasis 3; and pseudohypoaldosteronism. Is an ortholog of human SCNN1G (sodium channel epithelial 1 subunit gamma). WB:WBGene00012117 T28B11.1 Enriched in coelomocyte; germ line; mc3; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fifteen chemicals including Cry5B; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like; F-box-like domain superfamily; F-box domain; and Phosphorylation site. WB:WBGene00012118 grsp-2 Enriched in several structures, including ABalaappppa; ABalapaappa; PVT; rect_D; and rectal epithelial cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eleven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq; proteomic; and microarray studies. WB:WBGene00012119 T28C6.3 Predicted to be located in membrane. WB:WBGene00012120 T28C6.5 Enriched in several structures, including ABalpppappp; ABplpapapa; ABpraaaappp; ABprpapapa; and somatic nervous system based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00012121 T28C6.7 Expressed in tail. WB:WBGene00012122 T28C6.8 Predicted to be located in lysosome; membrane; and perinuclear region of cytoplasm. WB:WBGene00012123 T28D6.3 Enriched in hypodermis; intestine; and sensory neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including methylmercuric chloride; Mercuric Chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00012124 T28D6.4 Predicted to be involved in protein localization to ciliary inversin compartment. Predicted to be located in ciliary inversin compartment. Is an ortholog of human ANKRD50 (ankyrin repeat domain containing 50). WB:WBGene00012125 T28D6.5 Predicted to be located in membrane. WB:WBGene00012126 T28D6.6 Predicted to enable GTP binding activity. Predicted to be involved in cytoplasmic translation. Predicted to be located in cytoplasm. Is an ortholog of human DRG1 (developmentally regulated GTP binding protein 1). WB:WBGene00012127 T28D6.7 Predicted to enable lipid binding activity. Is an ortholog of human STARD10 (StAR related lipid transfer domain containing 10). WB:WBGene00012128 nra-1 Predicted to enable calcium-dependent phospholipid binding activity. Involved in receptor localization to synapse. Located in plasma membrane. Expressed in body wall musculature; head neurons; tail neurons; and ventral cord neurons. Is an ortholog of human CPNE5 (copine 5) and CPNE9 (copine family member 9). WB:WBGene00012130 slc-17.4 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be located in membrane. WB:WBGene00012131 T28F3.5 Predicted to enable acetyl-CoA carboxylase activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to be located in mitochondrion. Is an ortholog of human ACACA (acetyl-CoA carboxylase alpha) and ACACB (acetyl-CoA carboxylase beta). WB:WBGene00012132 ifta-2 Predicted to enable GTPase activity. Involved in several processes, including dauer larval development; determination of adult lifespan; and insulin-like growth factor receptor signaling pathway. Located in axoneme and ciliary base. Expressed in amphid neurons and phasmid neurons. Is an ortholog of human IFT22 (intraflagellar transport 22). WB:WBGene00012133 T28F3.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; dpy-21; and let-418 based on RNA-seq studies. WB:WBGene00012134 T28F3.8 Enriched in I5 neuron; cholinergic neurons; head mesodermal cell; and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including bisphenol S; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00012135 T28F3.9 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00012136 T28F4.1 Enriched in AFD; ASER; MSpaaapa; PLM; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and let-7 based on tiling array; proteomic; RNA-seq; and microarray studies. Is affected by eight chemicals including Zidovudine; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00012137 asic-2 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Expressed in ciliated neurons and sensory neurons. Human ortholog(s) of this gene implicated in bronchiectasis (multiple); neuroblastoma; and renal tubular transport disease (multiple). Is an ortholog of human SCNN1A (sodium channel epithelial 1 subunit alpha); SCNN1B (sodium channel epithelial 1 subunit beta); and SCNN1G (sodium channel epithelial 1 subunit gamma). WB:WBGene00012138 T28F4.3 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in motor neuron axon guidance. WB:WBGene00012139 T28F4.4 Predicted to be involved in anatomical structure morphogenesis. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in ACTH-independent macronodular adrenal hyperplasia 2. Is an ortholog of human ARMC5 (armadillo repeat containing 5). WB:WBGene00012140 T28F4.5 Predicted to enable death domain binding activity. Predicted to be involved in apoptotic signaling pathway; cellular response to amino acid starvation; and negative regulation of autophagy. Is an ortholog of human DAP (death associated protein). WB:WBGene00012142 T28H10.1 Predicted to enable holo-[acyl-carrier-protein] synthase activity. Predicted to be involved in lysine biosynthetic process via aminoadipic acid. Predicted to be located in cytosol. Is an ortholog of human AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase). WB:WBGene00012143 T28H10.2 Enriched in hypodermis; muscle cell; and sensory neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; D-glucose; and Psoralens based on microarray and RNA-seq studies. Human THAP4 enables several functions, including heme binding activity; identical protein binding activity; and peroxynitrite isomerase activity. Is predicted to encode a protein with the following domains: ShKT domain; Nitrobindin family; ShK domain-like; THAP4-like, heme-binding beta-barrel domain; and Calycin. Is an ortholog of human THAP4 (THAP domain containing 4). WB:WBGene00012144 lgmn-1 Predicted to enable cysteine-type endopeptidase activity. Involved in PERK-mediated unfolded protein response. Predicted to be located in vacuole. Is an ortholog of human LGMN (legumain). WB:WBGene00012145 nlp-46 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00012146 VB0393L.2 Enriched in intestine; neurons; retrovesicular ganglion; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00012147 VC27A7L.1 Expressed in neurons. WB:WBGene00012148 inos-1 Predicted to enable inositol-3-phosphate synthase activity. Predicted to be involved in inositol biosynthetic process. Predicted to be located in cytoplasm. Expressed in germ line. Is an ortholog of human ISYNA1 (inositol-3-phosphate synthase 1). WB:WBGene00012149 VF13D12L.3 Predicted to enable oxidoreductase activity. WB:WBGene00012150 syx-17 Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in autophagosome membrane; endomembrane system; and plasma membrane. Predicted to be part of SNARE complex. Is an ortholog of human STX17 (syntaxin 17). WB:WBGene00012151 VH15N14R.1 Enriched in several structures, including ABalaapppa; ABalapaaaa; ciliated neurons; g2; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including rotenone; D-glucose; and allantoin based on RNA-seq and microarray studies. WB:WBGene00012152 cnc-10 Enriched in several structures, including accessory cell; arc ant V; hyp3; rectal gland cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and sek-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including rotenone; bisphenol S; and Alovudine based on RNA-seq studies. WB:WBGene00012155 VW02B12L.2 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00012156 ebp-2 Predicted to enable microtubule plus-end binding activity. Predicted to be involved in protein localization to microtubule; regulation of microtubule polymerization or depolymerization; and spindle assembly. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and non-motile cilium. Expressed in several structures, including hypodermis; nervous system; and ventral nerve cord. WB:WBGene00012157 adbp-1 Involved in positive regulation of protein localization to nucleus. Located in nucleus. Expressed in hyp7 syncytium; intestine; neurons; pharynx; and seam cell. WB:WBGene00012158 ucr-2.1 Predicted to enable metal ion binding activity. Predicted to be located in mitochondrion. Expressed in gonad. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 5. Is an ortholog of human UQCRC2 (ubiquinol-cytochrome c reductase core protein 2). WB:WBGene00012159 VY10G11R.1 Predicted to enable histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. WB:WBGene00012162 sek-6 Predicted to enable JUN kinase kinase activity. Predicted to be involved in MAPK cascade. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); invasive ductal carcinoma; and prostate carcinoma in situ. Is an ortholog of human MAP2K4 (mitogen-activated protein kinase kinase 4). WB:WBGene00012163 VZK822L.2 Predicted to be located in membrane. WB:WBGene00012164 W01A8.2 Predicted to be located in cytoplasm. Is an ortholog of human C15orf40 (chromosome 15 open reading frame 40). WB:WBGene00012165 cutl-6 Predicted to be located in membrane. WB:WBGene00012166 nuo-6 Predicted to be located in membrane and mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Expressed in body wall musculature; germ line; gonad; and hypodermis. Is an ortholog of human NDUFB4 (NADH:ubiquinone oxidoreductase subunit B4). WB:WBGene00012167 tofu-5 Expressed in germ cell. WB:WBGene00012168 W01A8.6 Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. WB:WBGene00012169 ttbk-4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Expressed in ASIL; ASIR; amphid neurons; and neurons. WB:WBGene00012170 W01B6.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00012171 W01B6.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: PapD-like superfamily. WB:WBGene00012172 W01B6.5 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00012173 W01B6.6 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00012174 W01B6.8 Predicted to be located in membrane. WB:WBGene00012175 W01C9.1 Enriched in several structures, including Z1.p; arcade cell; male distal tip cell; pharynx; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00012176 W01C9.2 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00012177 decr-1.2 Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Is an ortholog of human DECR1 (2,4-dienoyl-CoA reductase 1). WB:WBGene00012178 glb-27 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00012179 W01D2.1 Predicted to enable RNA binding activity. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL37 (ribosomal protein L37). WB:WBGene00012180 W01D2.3 Predicted to be located in membrane. WB:WBGene00012181 srt-11 Predicted to be located in membrane. WB:WBGene00012182 osta-3 Predicted to be located in membrane. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Is an ortholog of human SLC51A (solute carrier family 51 subunit alpha). WB:WBGene00012183 W01D2.6 Predicted to be located in membrane. WB:WBGene00012184 mnr-1 Involved in neuron development and regulation of cell morphogenesis. Located in extracellular space and plasma membrane. Expressed in ALA; pharynx; and tail neurons. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Is an ortholog of human FAM151B (family with sequence similarity 151 member B). WB:WBGene00012185 W01F3.2 Enriched in AIB; SIB; germline precursor cell; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including 1-methylnicotinamide; manganese chloride; and sodium arsenite based on RNA-seq; microarray; and proteomic studies. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and carcinoma (multiple). Human MMP9 enables identical protein binding activity; metalloendopeptidase activity; and serine-type endopeptidase activity. Is predicted to encode a protein with the following domain: Hemopexin-like domain superfamily. Is an ortholog of human MMP2 (matrix metallopeptidase 2); MMP23B (matrix metallopeptidase 23B); and MMP9 (matrix metallopeptidase 9). WB:WBGene00012186 mlt-11 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular space. Expressed in hypodermis. WB:WBGene00012187 rpb-11 Predicted to enable protein dimerization activity. Predicted to contribute to RNA polymerase II activity. Predicted to be involved in DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II, core complex. Is an ortholog of human POLR2J (RNA polymerase II subunit J); POLR2J2 (RNA polymerase II subunit J2); and POLR2J3 (RNA polymerase II subunit J3). WB:WBGene00012188 W01G7.4 Predicted to be involved in developmental process. Predicted to be located in cytoplasm and nucleus. WB:WBGene00012189 W02A2.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; glycine; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00012190 W02A2.5 Predicted to be located in membrane. WB:WBGene00012191 W02A2.8 Predicted to be involved in positive regulation of ERAD pathway and response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum. WB:WBGene00012192 W02A11.1 Predicted to enable tRNA (adenine-N1-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to be located in nucleus. Predicted to be part of tRNA (m1A) methyltransferase complex. Is an ortholog of human TRMT61A (tRNA methyltransferase 61A). WB:WBGene00012193 vps-25 Predicted to enable protein homodimerization activity and structural molecule activity. Predicted to be involved in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be part of ESCRT II complex. Expressed in body wall musculature; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human VPS25 (vacuolar protein sorting 25 homolog). WB:WBGene00012194 toe-4 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Expressed in head. Is an ortholog of human RNF111 (ring finger protein 111). WB:WBGene00012195 bath-34 Enriched in AVK; germ line; and germline precursor cell based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily; BTB/POZ domain; and MATH/TRAF domain. WB:WBGene00012196 bath-35 Enriched in I5 neuron; cholinergic neurons; germline precursor cell; and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including daf-2; elt-2; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00012197 W02B8.1 Predicted to be located in membrane. WB:WBGene00012198 citk-1 Predicted to be involved in actomyosin structure organization. Predicted to be located in cytoplasm and cytoskeleton. WB:WBGene00012199 mltn-3 Predicted to be located in membrane. WB:WBGene00012200 mltn-4 Enriched in NSM; XXXL; and XXXR based on tiling array and single-cell RNA-seq studies. Is affected by several genes including rrf-3; clk-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00012201 W02B12.1 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Is an ortholog of human PLB1 (phospholipase B1). WB:WBGene00012202 cest-15 Enriched in excretory cell; neurons; and retrovesicular ganglion based on tiling array and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Lithium Chloride; sucrose; and stearic acid based on microarray and RNA-seq studies. WB:WBGene00012203 rga-1 Enables GTPase regulator activity. Predicted to be involved in negative regulation of endocytic recycling and small GTPase mediated signal transduction. Predicted to be located in cytoplasm. Is an ortholog of human ARHGAP1 (Rho GTPase activating protein 1). WB:WBGene00012204 mfn-1 Predicted to enable ferrous iron transmembrane transporter activity. Predicted to be involved in iron import into the mitochondrion. Predicted to be located in mitochondrial membrane. Is an ortholog of human SLC25A28 (solute carrier family 25 member 28). WB:WBGene00012205 metl-1 Predicted to enable tRNA (guanine-N7-)-methyltransferase activity. Predicted to be involved in RNA (guanine-N7)-methylation and tRNA methylation. Predicted to be located in nucleus. Predicted to be part of tRNA methyltransferase complex. Is an ortholog of human METTL1 (methyltransferase 1, tRNA methylguanosine). WB:WBGene00012206 W02B12.11 Predicted to enable N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity; beta-1,4-N-acetylgalactosaminyltransferase activity; and galactosyltransferase activity. Predicted to be involved in glycosphingolipid biosynthetic process. Predicted to be located in Golgi apparatus. Expressed in several structures, including body wall musculature; hermaphrodite gonad; hypodermis; intestine; and vulva. WB:WBGene00012207 W02B12.12 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cellular response to glucose starvation; intracellular signal transduction; and negative regulation of TOR signaling. Predicted to be part of nucleotide-activated protein kinase complex. WB:WBGene00012208 W02D9.2 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in trans-Golgi network. Is an ortholog of human YIPF6 (Yip1 domain family member 6). WB:WBGene00012209 hmg-20 Predicted to enable DNA binding activity. Predicted to be involved in regulation of gene expression. Predicted to be located in nucleus. Expressed in body wall musculature; head neurons; seam cell; ventral nerve cord; and vulval muscle. Is an ortholog of human HMG20A (high mobility group 20A). WB:WBGene00012210 W02D9.4 Enriched in AFD; germ line; germline precursor cell; head mesodermal cell; and head neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including manganese chloride; bisphenol S; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00012211 ssp-37 Involved in defense response to Gram-negative bacterium. WB:WBGene00012212 W02D9.6 Enriched in AVK; anterior spermatheca; and posterior spermatheca based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including 1-methylnicotinamide; rotenone; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00012213 W02D9.7 Enriched in RIM; interneuron; intestine; and spermatheca based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by fourteen chemicals including hydrogen sulfide; Ethanol; and rotenone based on microarray and RNA-seq studies. WB:WBGene00012214 W02D9.8 Predicted to be located in membrane. WB:WBGene00012215 W02D9.9 Predicted to be located in membrane. WB:WBGene00012216 dpsm-1 Enriched in several structures, including ABalapppaa; arcade cell; head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nineteen chemicals including Lithium Chloride; rotenone; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00012217 W02H3.1 Enriched in AWAL; AWAR; intestine; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00012218 W02H3.2 Enriched in RID based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. WB:WBGene00012219 W03C9.1 Predicted to be located in membrane. WB:WBGene00012220 W03C9.2 Located in striated muscle dense body. WB:WBGene00012221 W03C9.5 Enriched in several structures, including germ line; hypodermis; intestine; sensory neurons; and ventral nerve cord based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; rotenone; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00012222 W03C9.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00012223 W03C9.8 Predicted to be located in membrane. WB:WBGene00012224 W03G11.2 Predicted to be involved in macromolecule localization. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Is an ortholog of human TMEM30A (transmembrane protein 30A) and TMEM30B (transmembrane protein 30B). WB:WBGene00012225 W03G11.3 Predicted to enable alpha-L-fucosidase activity. Predicted to be involved in fucose metabolic process and glycoside catabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in fucosidosis; type 1 diabetes mellitus; and type 2 diabetes mellitus. Is an ortholog of human FUCA1 (alpha-L-fucosidase 1) and FUCA2 (alpha-L-fucosidase 2). WB:WBGene00012226 W03G11.4 Enriched in several structures, including XXX cell; accessory cell; distal tip cell; neurons; and pharyngeal cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; bisphenol S; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00012227 W03H9.1 Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1280); Protein of unknown function DUF1280; and Zinc finger, FYVE/PHD-type. WB:WBGene00012228 W03H9.2 Enriched in several structures, including ABalaaaala; ABalaapaaa; AVA; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00012230 cacn-1 Predicted to enable RNA binding activity. Involved in several processes, including gonad development; positive regulation of cell migration; and regulation of Wnt signaling pathway. Located in cytoplasm and nucleus. Part of spliceosomal complex. Expressed in several structures, including germ line; hermaphrodite gonad; hypodermal cell; intestine; and vulva. Is an ortholog of human CACTIN (cactin, spliceosome C complex subunit). WB:WBGene00012231 W04A4.2 Enriched in several structures, including ADL; DVA; germ line; gonadal sheath cell; and interfacial epithelial cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00012232 W04A4.3 Predicted to enable oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor. Predicted to be located in membrane. WB:WBGene00012233 clpr-1 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00012234 ints-4 Predicted to be involved in snRNA processing. Predicted to be part of integrator complex. Is an ortholog of human INTS4 (integrator complex subunit 4). WB:WBGene00012235 W04A4.6 Enriched in amphid neurons; intestine; muscle cell; rectal muscle; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; hsf-1; and sir-2.1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by six chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00012236 W04A8.1 Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endometrial cancer; and primary autosomal recessive microcephaly 1. Is an ortholog of human MCPH1 (microcephalin 1). WB:WBGene00012237 W04A8.2 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; ced-3; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00012238 W04A8.3 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalaappppa; ABalapaappa; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00012239 W04A8.4 Predicted to enable 3'-5' exonuclease activity and nucleic acid binding activity. Predicted to be involved in nucleobase-containing compound metabolic process and regulation of macromolecule metabolic process. Located in endoplasmic reticulum. WB:WBGene00012240 W04A8.5 Enriched in several structures, including AVE; NSM; body wall muscle cell; germ line; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and stavudine based on microarray and RNA-seq studies. WB:WBGene00012241 W04A8.6 Enriched in several structures, including ABalppppaa; ABarpapaaa; NSM; PLM; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012242 srt-39 Predicted to be located in membrane. WB:WBGene00012243 W04D2.4 Enriched in ABalpapppa; ABarapappa; germ line; intestine; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; gld-1; and sir-2.1 based on RNA-seq; microarray; and proteomic studies. Is affected by eight chemicals including Linolenic Acids; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012244 mrps-11 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS11 (mitochondrial ribosomal protein S11). WB:WBGene00012245 rbm-25 Predicted to enable mRNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Is an ortholog of human RBM25 (RNA binding motif protein 25). WB:WBGene00012246 fbxa-131 Is affected by drh-3 and mdt-15 based on RNA-seq and microarray studies. Is affected by allantoin based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00012247 W04E12.2 Predicted to be located in membrane. WB:WBGene00012248 W04E12.3 Predicted to be located in membrane. WB:WBGene00012249 W04E12.4 Predicted to be located in membrane. WB:WBGene00012250 W04E12.5 Predicted to be located in membrane. WB:WBGene00012251 clec-49 Predicted to enable monosaccharide binding activity and signaling receptor activity. Predicted to be located in extracellular region. WB:WBGene00012252 W04E12.7 Predicted to enable cysteine-type peptidase activity and kinase activity. Predicted to be involved in phosphorylation and proteolysis. WB:WBGene00012253 clec-50 Predicted to enable signaling receptor activity. Expressed in intestine. WB:WBGene00012254 W04E12.9 Predicted to be located in membrane. WB:WBGene00012255 lpr-6 Predicted to be involved in lipid transport. Predicted to be located in extracellular region. Expressed in amphid neurons. WB:WBGene00012256 lpr-5 Predicted to be involved in lipid transport. Predicted to be located in extracellular region. Expressed in several structures, including seam cell. WB:WBGene00012257 lpr-4 Predicted to be involved in lipid transport. Predicted to be located in extracellular region. Expressed in body wall musculature and muscle cell. WB:WBGene00012258 W04G3.5 Predicted to enable ATP binding activity and ribose phosphate diphosphokinase activity. Predicted to be involved in 5-phosphoribose 1-diphosphate biosynthetic process and purine nucleotide biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of ribose phosphate diphosphokinase complex. Is an ortholog of human PRPSAP1 (phosphoribosyl pyrophosphate synthetase associated protein 1) and PRPSAP2 (phosphoribosyl pyrophosphate synthetase associated protein 2). WB:WBGene00012259 sulp-7 Predicted to enable salt transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Predicted to be located in membrane. Expressed in body wall musculature; hypodermis; intestine; pharyngeal muscle cell; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including Pendred Syndrome; autosomal recessive nonsyndromic deafness (multiple); and bone disease (multiple). Is an ortholog of several human genes including SLC26A2 (solute carrier family 26 member 2); SLC26A3 (solute carrier family 26 member 3); and SLC26A4 (solute carrier family 26 member 4). WB:WBGene00012260 W04G3.7 Enriched in AIZL; AIZR; anterior arcade cell; and arcade cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by tryptophan; glycine; and Oligosaccharides based on microarray and RNA-seq studies. WB:WBGene00012261 lpr-3 Predicted to be involved in lipid transport. Predicted to be located in extracellular region. Expressed in excretory system and vulva. WB:WBGene00012263 W04G5.1 No description available WB:WBGene00012264 W04G5.3 Enriched in intestine based on microarray studies. Is affected by several genes including hpl-2; his-24; and mep-1 based on RNA-seq and microarray studies. WB:WBGene00012265 W04G5.4 Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Predicted to be involved in glycoprotein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Predicted to be located in cytosol and nucleus. WB:WBGene00012266 W04G5.5 Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Predicted to be involved in glycoprotein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Predicted to be located in cytosol and nucleus. WB:WBGene00012267 W04G5.7 Enriched in body wall muscle cell; head mesodermal cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including pie-1; pgl-1; and glh-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF684) and Protein of unknown function DUF684. WB:WBGene00012268 W04G5.8 Enriched in several structures, including ABplpappaa; MSpaaapa; head mesodermal cell; nerve ring neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including pie-1; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Sodium Chloride; allantoin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF684) and Protein of unknown function DUF684. WB:WBGene00012269 W04G5.9 Predicted to enable hydrolase activity. Predicted to be involved in glycoprotein catabolic process. Predicted to be located in cytoplasm. WB:WBGene00012270 W04G5.10 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Is an ortholog of human FLT3 (fms related receptor tyrosine kinase 3) and TEK (TEK receptor tyrosine kinase). WB:WBGene00012271 W05B2.2 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00012272 dhc-4 Enriched in several structures, including ABalaapppa; ABalapaapa; ciliated neurons; hyp3; and ventral nerve cord based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including manganese chloride; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Dynein heavy chain, domain 2, N-terminal; P-loop containing nucleoside triphosphate hydrolase; Dynein heavy chain, linker; and Dynein heavy chain, N-terminal region 2. WB:WBGene00012274 W05B5.1 Enriched in head mesodermal cell; intestine; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by seventeen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012275 npr-14 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in AIYL and AIYR. Is an ortholog of human HCRTR1 (hypocretin receptor 1) and HCRTR2 (hypocretin receptor 2). WB:WBGene00012276 his-74 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in nucleus. Predicted to be part of nucleosome. Expressed in male. WB:WBGene00012277 ccch-3 Predicted to enable metal ion binding activity. Predicted to be located in nucleus. Expressed in dorsal nerve cord; head muscle; head neurons; intestine; and ventral nerve cord. WB:WBGene00012278 W05B10.3 Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00012279 W05B10.4 Predicted to be involved in positive regulation of epidermal growth factor receptor signaling pathway and positive regulation of fibroblast growth factor receptor signaling pathway. Expressed in several structures, including P5.ppal; P5.ppp; P7.paa; pharynx; and vulval cell. WB:WBGene00012280 W05E10.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00012281 W05E10.2 Predicted to be located in membrane. WB:WBGene00012282 W05E10.5 Enriched in head mesodermal cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by six chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00012283 W05H5.1 Predicted to be located in membrane. WB:WBGene00012284 W05H5.2 Is affected by several genes including sir-2.1; hpl-2; and drh-3 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00012285 pitr-6 Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Is an ortholog of human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2). WB:WBGene00012286 sre-35 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00012287 sre-33 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00012288 sre-32 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00012289 W05H12.1 Predicted to be located in membrane. Expressed in dorsal nerve cord; head neurons; tail neurons; and ventral nerve cord. WB:WBGene00012290 W05H12.2 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; head mesodermal cell; neurons; and ventral nerve cord based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by Psoralens based on RNA-seq studies. WB:WBGene00012291 W06A7.2 Located in plasma membrane. WB:WBGene00012292 C11E4.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00012293 W06A7.4 Predicted to enable carbohydrate transmembrane transporter activity. Predicted to be involved in carbohydrate transmembrane transport. Predicted to be located in membrane. WB:WBGene00012294 nspa-8 Enriched in amphid sheath cell; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including hydrogen sulfide; Ethanol; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00012295 nmat-1 Predicted to enable nicotinamide-nucleotide adenylyltransferase activity and nicotinate-nucleotide adenylyltransferase activity. Predicted to be involved in NAD biosynthetic process. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9 and spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis. Is an ortholog of human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1) and NMNAT3 (nicotinamide nucleotide adenylyltransferase 3). WB:WBGene00012296 spe-46 Predicted to be located in membrane. Expressed in sperm. WB:WBGene00012297 W06D4.3 Predicted to be located in cytoplasm. WB:WBGene00012298 prmt-7 Predicted to enable protein-arginine omega-N monomethyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human PRMT7 (protein arginine methyltransferase 7). WB:WBGene00012299 W06D11.1 Enriched in several structures, including ABalpapaap; BAG; RID; germ line; and male distal tip cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; rrf-3; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including bisphenol A; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00012300 W06D11.2 Enriched in AINL; AINR; BAG; MSaapapa; and MSpapapa based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pmk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00012301 W06D11.3 Enriched in germ line; neurons; and pharynx based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including bisphenol A; tert-Butylhydroperoxide; and metformin based on RNA-seq and microarray studies. WB:WBGene00012302 dot-1.3 Predicted to enable histone H3K79 methyltransferase activity. Predicted to be involved in DNA damage checkpoint signaling and DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in acute biphenotypic leukemia. Is an ortholog of human DOT1L (DOT1 like histone lysine methyltransferase). WB:WBGene00012303 W06D11.5 Is affected by several genes including daf-2; sir-2.1; and drh-3 based on microarray and RNA-seq studies. Is affected by four chemicals including Tunicamycin; dibromoacetic acid; and 2 based on microarray studies. WB:WBGene00012304 cutl-4 Predicted to be located in membrane. WB:WBGene00012305 W06D12.6 Predicted to enable monooxygenase activity. WB:WBGene00012306 W06F12.2 Predicted to be located in membrane. WB:WBGene00012307 W06F12.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00012308 oac-53 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00012309 W06G6.2 Enriched in ASIL; ASIR; and Caapa based on single-cell RNA-seq studies. Is affected by cyc-1 and clk-1 based on microarray studies. WB:WBGene00012310 mltn-11 Predicted to be located in membrane. WB:WBGene00012311 W06G6.9 Is affected by several genes including let-60; pmk-1; and nhr-49 based on microarray and RNA-seq studies. Is affected by four chemicals including silicon dioxide nanoparticle; Colistin; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00012312 W06G6.10 Enriched in body wall muscle cell; coelomocyte; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; pmk-1; and nhr-49 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including methylmercury hydroxide; mianserin; and procyanidin based on RNA-seq and microarray studies. WB:WBGene00012313 W06G6.11 Is affected by several genes including clk-1; bar-1; and alg-1 based on microarray and RNA-seq studies. WB:WBGene00012314 W06G6.12 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; hda-1; and daf-10 based on microarray studies. Is affected by Rifampin based on RNA-seq studies. WB:WBGene00012315 immt-2 Involved in cristae formation; mitochondrion morphogenesis; and response to reactive oxygen species. Located in mitochondrial inner membrane. Part of mitochondrial proton-transporting ATP synthase complex. Is an ortholog of human IMMT (inner membrane mitochondrial protein). WB:WBGene00012316 ctps-1 Predicted to enable CTP synthase activity and identical protein binding activity. Predicted to be involved in CTP biosynthetic process and pyrimidine nucleobase biosynthetic process. Predicted to be located in cytoophidium and cytoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in biliary tract benign neoplasm; colorectal cancer; and immunodeficiency 24. Is an ortholog of human CTPS1 (CTP synthase 1) and CTPS2 (CTP synthase 2). WB:WBGene00012317 ztf-6 Predicted to enable chromatin insulator sequence binding activity. Involved in asymmetric stem cell division; cell fate specification; and positive regulation of gene expression. Predicted to be located in chromosome. Expressed in several structures, including V5L.a; head muscle; hypodermis; postdeirid sensillum; and tail. WB:WBGene00012318 srxa-1 Predicted to be located in membrane. Expressed in ADFL; ADFR; AWBL; and AWBR. WB:WBGene00012319 ipla-3 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including Duchenne muscular dystrophy; Parkinson's disease 14; dystonia 12; and neurodegeneration with brain iron accumulation (multiple). Is an ortholog of human PLA2G6 (phospholipase A2 group VI). WB:WBGene00012320 srxa-3 Enriched in sensory neurons based on RNA-seq studies. Is affected by dpy-21 and acs-3 based on RNA-seq and microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00012321 srxa-6 Predicted to be located in membrane. Expressed in ASIL; ASIR; PHBL; and PHBR. WB:WBGene00012322 W07A12.4 Enriched in PLM; SAA; muscle cell; and tail hypodermis based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including levamisole; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily; BTB/POZ domain; BTB/Kelch-associated; and BTB And C-terminal Kelch. Is an ortholog of human BTBD17 (BTB domain containing 17). WB:WBGene00012323 oac-54 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00012324 rhy-1 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Involved in negative regulation of cellular response to hypoxia and response to hypoxia. Located in perinuclear region of cytoplasm. Expressed in body wall musculature; hypodermis; neurons; socket cell; and vulva. WB:WBGene00012325 W07A12.8 Enriched in intestine; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including methylmercuric chloride; rotenone; and indole based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CoA-transferase family III domain 1 superfamily. WB:WBGene00012326 W07E11.1 Predicted to enable glutamate synthase (NADH) activity. Predicted to be involved in ammonia assimilation cycle and glutamate biosynthetic process. WB:WBGene00012328 W07G1.1 Predicted to be involved in intracellular signal transduction. Predicted to be located in microtubule and microtubule organizing center. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; autosomal recessive nonsyndromic deafness 66; and dyslexia. Is an ortholog of human DCDC2 (doublecortin domain containing 2) and DCDC2C (doublecortin domain containing 2C). WB:WBGene00012329 sre-44 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00012330 zip-3 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in mitochondrial unfolded protein response and negative regulation of innate immune response. Located in nucleus. Is an ortholog of human ATF5 (activating transcription factor 5). WB:WBGene00012332 rpi-1 Predicted to be involved in intracellular signal transduction. Located in axonemal microtubule; ciliary base; and ciliary transition zone. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; autosomal recessive nonsyndromic deafness 66; and dyslexia. Is an ortholog of human DCDC2 (doublecortin domain containing 2); DCDC2B (doublecortin domain containing 2B); and DCDC2C (doublecortin domain containing 2C). WB:WBGene00012333 sre-43 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in AWB and chemosensory neurons. WB:WBGene00012334 W07G1.7 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00012335 W07G4.1 Enriched in hypodermis based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00012336 W07G4.2 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00012337 scyl-1 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Expressed in excretory cell; intestinal cell; spermatheca; uterine epithelial cell; and ventral cord neurons. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 21. Is an ortholog of human SCYL1 (SCY1 like pseudokinase 1). WB:WBGene00012339 W07G4.5 Enriched in head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00012340 dct-15 Predicted to enable glucose transmembrane transporter activity. Predicted to be involved in glucose transmembrane transport. Predicted to be located in membrane. WB:WBGene00012341 catp-6 Predicted to enable ATPase-coupled monoatomic cation transmembrane transporter activity and polyamine transmembrane transporter activity. Involved in protein folding. Located in cytoplasmic vesicle and plasma membrane. Expressed in several structures, including egg-laying apparatus; gonad; oocyte; pharynx; and somatic gonad precursor. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Is an ortholog of human ATP13A3 (ATPase 13A3). WB:WBGene00012342 mtr-4 Predicted to enable RNA helicase activity. Predicted to be involved in RNA catabolic process and maturation of 5.8S rRNA. Predicted to be located in nucleus. Expressed in PVDL; PVDR; embryonic cell; and somatic cell. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is an ortholog of human MTREX (Mtr4 exosome RNA helicase). WB:WBGene00012343 casc-3 Predicted to enable mRNA binding activity. Predicted to be involved in RNA metabolic process; mRNA transport; and regulation of translation. Predicted to be located in cell projection; nuclear speck; and perinuclear region of cytoplasm. Predicted to be part of exon-exon junction complex. Expressed widely. Is an ortholog of human CASC3 (CASC3 exon junction complex subunit). WB:WBGene00012344 ola-1 Predicted to enable ATP hydrolysis activity. Involved in behavioral response to starvation; thermosensory behavior; and thermotaxis. Located in endoplasmic reticulum. Expressed in nervous system and pharyngeal muscle cell. Is an ortholog of human OLA1 (Obg like ATPase 1). WB:WBGene00012345 W08E3.4 Enriched in several structures, including ABalpppapa; ABaraappaa; ABplapppaa; neuronal sheath cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Immunoglobulin-like fold and PapD-like superfamily. WB:WBGene00012346 W08G11.1 Predicted to be located in membrane. WB:WBGene00012347 W08G11.3 Enriched in AVK; RID; and germ line based on RNA-seq studies. Is affected by several genes including hsf-1; sir-2.1; and clk-1 based on microarray; RNA-seq; and proteomic studies. Is affected by five chemicals including Zidovudine; paraquat; and resveratrol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012348 pptr-1 Enables protein kinase binding activity and protein phosphatase activator activity. Contributes to protein serine/threonine phosphatase activity. Involved in several processes, including P granule assembly; determination of adult lifespan; and negative regulation of insulin receptor signaling pathway. Located in cytosol. Expressed in head; spermatheca; tail; and vulva. Used to study cancer. Is an ortholog of human PPP2R5E (protein phosphatase 2 regulatory subunit B'epsilon). WB:WBGene00012349 W08G11.5 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00012350 C11G10.t1 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00012351 W09C5.1 Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Located in nucleolus. Expressed in ventral nerve cord. Is an ortholog of human NSA2 (NSA2 ribosome biogenesis factor). WB:WBGene00012352 dkf-1 Enables protein serine/threonine kinase activity. Involved in several processes, including defense response to Gram-positive bacterium; determination of adult lifespan; and positive regulation of protein import into nucleus. Located in several cellular components, including axon; cell cortex; and somatodendritic compartment. Expressed in neurons. WB:WBGene00012353 sac-2 Predicted to enable phosphatidylinositol-4-phosphate phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation and regulation of endocytic recycling. Predicted to be located in clathrin-coated endocytic vesicle and early endosome. Is an ortholog of human INPP5F (inositol polyphosphate-5-phosphatase F). WB:WBGene00012354 cox-4 Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX4I1 (cytochrome c oxidase subunit 4I1) and COX4I2 (cytochrome c oxidase subunit 4I2). WB:WBGene00012355 W09C5.9 Enriched in AVE; intestine; and ventral nerve cord based on tiling array and microarray studies. Is affected by several genes including daf-16; lin-4; and lin-14 based on microarray and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00012356 W09D6.1 Predicted to be involved in amino acid activation for nonribosomal peptide biosynthetic process. Is an ortholog of human AASDH (aminoadipate-semialdehyde dehydrogenase). WB:WBGene00012357 W09D6.4 Enriched in germ line; hypodermis; interfacial epithelial cell; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including Lithium Chloride; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00012358 W09D6.5 Enriched in several structures, including ABarpaapap; ABarpaappa; anterior hypodermis; pm8; and rectal epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00012359 smap-1 Predicted to enable GTPase activator activity. Predicted to be located in cytoplasm. Is an ortholog of human SMAP1 (small ArfGAP 1). WB:WBGene00012360 tat-3 Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Involved in sterol metabolic process. Predicted to be located in plasma membrane. Expressed in several structures, including XXX cell; anchor cell; distal tip cell; pharynx; and vulva. Is an ortholog of human ATP10A (ATPase phospholipid transporting 10A (putative)) and ATP10D (ATPase phospholipid transporting 10D (putative)). WB:WBGene00012361 mrpl-12 Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 45. Is an ortholog of human MRPL12 (mitochondrial ribosomal protein L12). WB:WBGene00012362 W09D10.4 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in mitochondrion. Is an ortholog of human PPTC7 (protein phosphatase targeting COQ7). WB:WBGene00012363 W09D10.5 Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be located in membrane. WB:WBGene00012364 zmp-4 Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to be located in extracellular matrix. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and carcinoma (multiple). Is an ortholog of human MMP2 (matrix metallopeptidase 2); MMP23B (matrix metallopeptidase 23B); and MMP9 (matrix metallopeptidase 9). WB:WBGene00012365 W09G3.1 Enriched in several structures, including ABalpapppa; germ line; head mesodermal cell; rectal epithelial cell; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including gld-2; sma-2; and smg-2 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Kelch-type beta propeller; Kelch repeat type 1; and Kelch motif. WB:WBGene00012366 maea-1 Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of GID complex. Is an ortholog of human MAEA (macrophage erythroblast attacher, E3 ubiquitin ligase). WB:WBGene00012368 fbxa-93 Enriched in AVK based on RNA-seq studies. Is affected by several genes including daf-2; unc-30; and mut-16 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Chlorpyrifos based on RNA-seq and microarray studies. WB:WBGene00012369 W09G3.6 Predicted to be involved in developmental pigmentation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 5. Is an ortholog of human HPS5 (HPS5 biogenesis of lysosomal organelles complex 2 subunit 2). WB:WBGene00012370 W09G3.7 Predicted to enable guanyl-nucleotide exchange factor activity and rRNA binding activity. Predicted to be involved in positive regulation of mitochondrial translation. Predicted to be located in mitochondrial inner membrane. Expressed in amphid neurons; hypodermis; and intestine. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Is an ortholog of human RCC1L (RCC1 like). WB:WBGene00012371 W09G3.8 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in COPII-coated ER to Golgi transport vesicle and endoplasmic reticulum membrane. Is an ortholog of human IER3IP1 (immediate early response 3 interacting protein 1). WB:WBGene00012372 W09H1.1 Predicted to enable phosphoprotein phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in cytoplasm. WB:WBGene00012373 W09H1.3 Predicted to be located in extracellular space. WB:WBGene00012374 W09H1.4 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaaaa; AVH; and GLR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00012375 mecr-1 Predicted to enable trans-2-enoyl-CoA reductase (NADPH) activity. Predicted to be involved in fatty acid metabolic process. Predicted to be located in mitochondrion. Expressed in tail. Human ortholog(s) of this gene implicated in dystonia. Is an ortholog of human MECR (mitochondrial trans-2-enoyl-CoA reductase). WB:WBGene00012376 nduf-7 Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in aerobic respiration; electron transport coupled proton transport; and mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Expressed in intestine. Human ortholog(s) of this gene implicated in bipolar disorder and nuclear type mitochondrial complex I deficiency 3. Is an ortholog of human NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7). WB:WBGene00012377 C12C8.t1 No description available WB:WBGene00012378 W10G6.1 Enriched in DA neuron; VA neuron; and body wall muscle cell based on tiling array studies. Is affected by several genes including eat-2; sir-2.1; and mex-3 based on microarray and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00012379 Y1A5A.1 Predicted to enable metal ion binding activity. WB:WBGene00012381 Y2H9A.4 Predicted to be located in membrane. WB:WBGene00012382 ttr-16 Predicted to be located in cell surface and extracellular region. WB:WBGene00012383 ttr-17 Predicted to be located in cell surface and extracellular region. WB:WBGene00012384 Y5F2A.3 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including cat-2; ain-1; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Atrazine and Chlorpyrifos based on microarray studies. WB:WBGene00012385 Y5F2A.4 Expressed in nerve ring and tail neurons. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type; Zinc finger, C2H2 type; and Zinc finger C2H2 superfamily. Is an ortholog of human ZNF28 (zinc finger protein 28). WB:WBGene00012386 agef-1 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in protein transport and regulation of ARF protein signal transduction. Expressed in coelomocyte; intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is an ortholog of human ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2). WB:WBGene00012387 Y6B3B.1 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Expressed in coelomocyte and hypodermis. WB:WBGene00012388 Y6B3B.3 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and aak-2 based on RNA-seq studies. Is affected by methylmercuric chloride and paraquat based on microarray and RNA-seq studies. WB:WBGene00012389 scpr-1 Enriched in AFD; AVK; arcade cell; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and sek-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including rotenone; Alovudine; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: S phase cyclin A-associated protein in the endoplasmic reticulum and S phase cyclin A-associated protein in the endoplasmic reticulum, N-terminal. Is an ortholog of human SCAPER (S-phase cyclin A associated protein in the ER). WB:WBGene00012390 gpap-1 Predicted to enable 3'-nucleotidase activity. Predicted to be located in endomembrane system. Human ortholog(s) of this gene implicated in chondrodysplasia with joint dislocations gPAPP type. Is an ortholog of human BPNT2 (3'(2'), 5'-bisphosphate nucleotidase 2). WB:WBGene00012391 Y6B3B.7 Predicted to be located in membrane. WB:WBGene00012392 Y6B3B.8 No description available WB:WBGene00012393 Y6B3B.9 Predicted to enable endonuclease activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be part of preribosome, large subunit precursor. Human ortholog(s) of this gene implicated in Wilson-Turner syndrome. Is an ortholog of human LAS1L (LAS1 like ribosome biogenesis factor). WB:WBGene00012394 hsd-1 Enables 3-beta-hydroxy-delta5-steroid dehydrogenase activity. Involved in nematode larval development and sterol biosynthetic process. Predicted to be located in membrane. Expressed in XXXL and XXXR. Human ortholog(s) of this gene implicated in CHILD syndrome and CK syndrome. Is an ortholog of human SDR42E1 (short chain dehydrogenase/reductase family 42E, member 1). WB:WBGene00012395 Y6D1A.1 Enriched in several structures, including ABarpapaapp; ABplaaaaapp; B cell; germ line; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and let-7 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012396 Y6D1A.2 Predicted to enable metal ion binding activity. WB:WBGene00012397 Y6E2A.1 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00012398 Y6E2A.4 Enriched in several structures, including coelomocyte; head mesodermal cell; male distal tip cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including Tunicamycin; levamisole; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF713) and Protein of unknown function DUF713. WB:WBGene00012399 Y6E2A.5 Enriched in several structures, including head mesodermal cell; male distal tip cell; neurons; retrovesicular ganglion; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including multi-walled carbon nanotube; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF713) and Protein of unknown function DUF713. WB:WBGene00012400 Y6E2A.7 Enriched in body wall muscle cell; dopaminergic neurons; head mesodermal cell; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Mercuric Chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF713. WB:WBGene00012401 irld-57 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain and Receptor L domain. WB:WBGene00012402 sfxn-1.3 Predicted to enable serine transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Predicted to be located in mitochondrial membrane. Is an ortholog of human SFXN1 (sideroflexin 1) and SFXN3 (sideroflexin 3). WB:WBGene00012403 srz-45 Expressed in chemosensory neurons. WB:WBGene00012404 Y6G8.2 Enriched in OLL; PVD; head mesodermal cell; and intestine based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Tunicamycin; D-glucopyranose; and tert-Butylhydroperoxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box domain. WB:WBGene00012405 ztf-25 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in embryonic cell; head muscle; intestine; and somatic nervous system. WB:WBGene00012406 srz-91 Predicted to be located in membrane. WB:WBGene00012407 Y7A5A.1 Predicted to enable delta24(24-1) sterol reductase activity. Predicted to be involved in steroid metabolic process. Predicted to be located in cytoplasm. WB:WBGene00012408 Y7A5A.2 Enriched in several structures, including PLM; PVT; intestine; muscle cell; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including mianserin; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00012409 Y7A5A.3 Enriched in ABplpapppa; neurons; retrovesicular ganglion; somatic gonad precursor; and in male based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by six chemicals including aldicarb; methylmercuric chloride; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00012411 Y7A5A.5 Enriched in coelomocyte; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including fluoranthene; paraquat; and tetrabromobisphenol A based on microarray studies. WB:WBGene00012412 Y7A5A.6 Enriched in several structures, including ABplpppaaa; ABprpppaaa; AFD; MSpaaapa; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; elt-2; and csr-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and paraquat based on RNA-seq and microarray studies. WB:WBGene00012413 Y7A5A.7 Enriched in muscle cell; neurons; and sensory neurons based on RNA-seq and microarray studies. Is affected by several genes including lin-22; hda-2; and etr-1 based on tiling array and RNA-seq studies. Is affected by fluoranthene based on microarray studies. WB:WBGene00012414 Y7A5A.8 Enriched in GLR; MSpppaaa; NSM; and head mesodermal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and glh-1 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00012415 Y7A5A.9 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Rifampin and Psoralens based on RNA-seq studies. WB:WBGene00012416 Y7A9A.1 Predicted to enable glutathione hydrolase activity. Predicted to be involved in glutathione catabolic process. Predicted to be located in plasma membrane. Is an ortholog of human GGT5 (gamma-glutamyltransferase 5). WB:WBGene00012418 Y7A9C.1 Enriched in intestine based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including aldicarb; methylmercuric chloride; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00012419 srz-73 Is affected by several genes including let-60; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00012420 Y7A9D.1 Enriched in several structures, including GLR; enteric muscle; g1; germ line; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00012421 Y9C2UA.1 Located in plasma membrane. WB:WBGene00012423 Y10G11A.1 Predicted to enable 5'-nucleotidase activity. Predicted to be involved in nucleotide metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human NT5C3B (5'-nucleotidase, cytosolic IIIB). WB:WBGene00012424 dlc-3 Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based process. Predicted to be located in cytoplasm and microtubule. Predicted to be part of cytoplasmic dynein complex. Expressed in body wall musculature; distal tip cell; and vulval muscle. WB:WBGene00012425 dlc-4 Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based process. Predicted to be located in cytoplasm and microtubule. Predicted to be part of cytoplasmic dynein complex. WB:WBGene00012426 Y11D7A.1 Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by bortezomib based on RNA-seq studies. WB:WBGene00012428 Y11D7A.3 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00012429 Y11D7A.5 Enriched in germline precursor cell; hypodermis; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on RNA-seq; tiling array; and microarray studies. Is affected by twenty-five chemicals including Heme; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00012430 Y11D7A.6 No description available WB:WBGene00012431 Y11D7A.7 Enriched in several structures, including AFD; RIB; germ line; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including rotenone; manganese chloride; and mianserin based on RNA-seq and microarray studies. WB:WBGene00012432 Y11D7A.8 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Expressed in amphid neurons. WB:WBGene00012433 Y11D7A.9 Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00012434 Y11D7A.10 Enriched in germ line; intestine; muscle cell; and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including hydrogen sulfide; D-glucose; and stearic acid based on microarray and RNA-seq studies. WB:WBGene00012435 flh-1 Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription and nematode larval development. WB:WBGene00012436 flh-3 Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription. WB:WBGene00012437 nmy-3 Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in muscle contraction and sarcomere organization. Predicted to be located in cytoplasm and myosin filament. Predicted to be part of myosin II complex. WB:WBGene00012439 Y12A6A.1 Located in membrane raft. WB:WBGene00012440 nlp-53 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00012441 glb-28 Predicted to enable heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00012442 Y15E3A.3 Predicted to enable transferase activity. WB:WBGene00012443 Y15E3A.4 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in plasma membrane. WB:WBGene00012444 Y15E3A.5 Enriched in several structures, including ABalppappa; ABarappppa; XXX cell; body wall musculature; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including rotenone; 4-bromodiphenyl ether; and Cadmium Chloride based on RNA-seq and microarray studies. WB:WBGene00012445 Y16B4A.2 Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. WB:WBGene00012446 nhr-230 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00012448 cyp-33D3 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Keshan disease; glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C19 (cytochrome P450 family 2 subfamily C member 19); and CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00012449 nhr-231 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons; intestine; pharynx; and rectal gland cell. WB:WBGene00012450 Y17D7B.2 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercury hydroxide; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00012451 Y17D7B.3 Enriched in AFD and FLP based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including copper sulfate; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00012452 Y17D7B.4 Enriched in head mesodermal cell; intestine; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including rotenone; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00012453 Y17D7B.5 Enriched in intestine; muscle cell; and neurons based on microarray studies. Is affected by several genes including daf-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by Alovudine; Chlorpyrifos; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00012454 clec-256 Enriched in pharynx based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Alovudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; C-type lectin fold; and PAN-3 domain. WB:WBGene00012455 Y17D7C.1 Enriched in several structures, including ABalaapppa; ABalapaaaa; ABalapaapa; ABalappaap; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by Rifampin and Sirolimus based on RNA-seq studies. WB:WBGene00012456 Y17D7C.2 Predicted to enable hydrolase activity. WB:WBGene00012457 acbp-6 Predicted to enable fatty-acyl-CoA binding activity. Predicted to be involved in fatty acid metabolic process. WB:WBGene00012458 ash-2 Predicted to enable transcription cis-regulatory region binding activity. Involved in determination of adult lifespan; programmed cell death; and transdifferentiation. Located in nucleus. Part of MLL3/4 complex. Expressed in germ line. Is an ortholog of human ASH2L (ASH2 like, histone lysine methyltransferase complex subunit). WB:WBGene00012459 Y17G7B.3 Predicted to enable hydroxyacylglutathione hydrolase activity. Predicted to be involved in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione. Is an ortholog of human HAGH (hydroxyacylglutathione hydrolase). WB:WBGene00012460 dhps-1 Predicted to enable deoxyhypusine synthase activity. Predicted to be located in cytoplasm. Is an ortholog of human DHPS (deoxyhypusine synthase). WB:WBGene00012461 glb-29 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00012462 Y17G7B.8 Involved in innate immune response. WB:WBGene00012463 nadk-2 Predicted to enable NAD+ kinase activity. Predicted to be involved in NAD metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human NADK2 (NAD kinase 2, mitochondrial). WB:WBGene00012464 arrd-7 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC2 (arrestin domain containing 2). WB:WBGene00012465 Y17G7B.12 Predicted to enable exonuclease activity. Predicted to be located in nucleus. Is an ortholog of human REXO4 (REX4 homolog, 3'-5' exonuclease). WB:WBGene00012466 ippk-1 Predicted to enable inositol pentakisphosphate 2-kinase activity. Predicted to be involved in inositol phosphate biosynthetic process. Predicted to be located in nucleus. Is an ortholog of human IPPK (inositol-pentakisphosphate 2-kinase). WB:WBGene00012467 arrd-8 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC2 (arrestin domain containing 2). WB:WBGene00012468 Y17G7B.17 Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human MLF2 (myeloid leukemia factor 2). WB:WBGene00012469 Y17G7B.18 Predicted to enable O-methyltransferase activity; RNA methyltransferase activity; and snRNA binding activity. Predicted to be involved in snRNA modification. Is an ortholog of human MEPCE (methylphosphate capping enzyme). WB:WBGene00012470 Y17G7B.19 Enriched in muscle cell and in male based on RNA-seq and microarray studies. Is affected by several genes including rrf-3; eat-2; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00012471 Y17G7B.20 Enriched in several structures, including ABalpapaap; AVK; germ line; pharyngeal neurons; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and gld-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Aspirin; Rifampin; and paraquat based on RNA-seq and microarray studies. WB:WBGene00012472 Y17G7B.21 Enriched in several structures, including ABaraappaa; ABarpapaaa; ABplaaaaaa; AVK; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by Rifampin; Sirolimus; and paraquat based on RNA-seq studies. WB:WBGene00012473 Y17G7B.22 Enriched in head mesodermal cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and alg-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00012474 attf-6 Predicted to be located in nucleus. Expressed in head muscle; head neurons; intestine; pharynx; and ventral nerve cord. WB:WBGene00012475 Y18D10A.2 Predicted to enable oxidoreductase activity. WB:WBGene00012476 Y18D10A.3 Predicted to enable NADHX epimerase activity. Is an ortholog of human NAXE (NAD(P)HX epimerase). WB:WBGene00012477 Y18D10A.4 Predicted to be located in membrane. WB:WBGene00012478 mxt-1 Predicted to enable eukaryotic initiation factor 4E binding activity and translation initiation factor activity. Predicted to be involved in positive regulation of translation and regulation of formation of translation initiation ternary complex. Predicted to be located in cytoplasm. Predicted to be part of RNA cap binding activity complex. WB:WBGene00012479 ciao-1 Predicted to be involved in iron-sulfur cluster assembly. Predicted to be part of CIA complex. Is an ortholog of human CIAO1 (cytosolic iron-sulfur assembly component 1). WB:WBGene00012480 clec-104 Enriched in ABalppappa and ABarappppa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and rrf-3 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by nine chemicals including multi-walled carbon nanotube; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00012481 Y18D10A.11 Predicted to be located in membrane. WB:WBGene00012482 clec-106 Enriched in male based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by resveratrol and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00012483 coa-5 Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 9. Is an ortholog of human COA5 (cytochrome c oxidase assembly factor 5). WB:WBGene00012484 car-1 Enables RNA polymerase II core promoter sequence-specific DNA binding activity. Involved in positive regulation of gene expression. Located in endoplasmic reticulum and intracellular non-membrane-bounded organelle. Part of messenger ribonucleoprotein complex. Expressed in germ line; gonad; neurons; somatic cell; and touch receptor neurons. Is an ortholog of human LSM14B (LSM family member 14B). WB:WBGene00012485 fbxa-121 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Atrazine; cadmium; and Chlorpyrifos based on microarray studies. WB:WBGene00012486 Y18D10A.21 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including aldicarb; methylmercuric chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00012487 Y18D10A.23 Predicted to be located in membrane. Expressed in excretory canal; excretory cell; and ut2. WB:WBGene00012488 clec-105 Enriched in NSM based on tiling array studies. Is affected by several genes including hpl-2; jmjd-3.1; and jmjd-1.2 based on tiling array and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00012489 Y19D2B.1 Predicted to enable GTP binding activity and hydrolase activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cytoskeleton organization and microtubule-based process. Predicted to be located in microtubule. WB:WBGene00012490 Y19D2B.2 Enriched in ABalaaaala and ABalaapaaa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00012491 Y20C6A.1 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; levamisole; and bortezomib based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box domain. WB:WBGene00012492 fbxb-7 Enriched in several structures, including accessory cell; amphid neurons; command interneuron; germ line; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00012493 Y20C6A.3 Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00012494 nhr-232 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00012496 Y24F12A.1 Predicted to enable hydrolase activity, acting on ester bonds. Is an ortholog of human TATDN2 (TatD DNase domain containing 2). WB:WBGene00012497 ragc-1 Predicted to enable GTPase activity. Involved in determination of adult lifespan and regulation of autophagosome assembly. Predicted to be located in lysosome and nucleus. Predicted to be part of Gtr1-Gtr2 GTPase complex. Human ortholog(s) of this gene implicated in primary hypomagnesemia. Is an ortholog of human RRAGC (Ras related GTP binding C) and RRAGD (Ras related GTP binding D). WB:WBGene00012498 Y24F12A.3 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; D-glucose; and allantoin based on RNA-seq and microarray studies. WB:WBGene00012499 Y24F12A.4 Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; rotenone; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00012500 hpo-2 Enriched in RID; body wall musculature; male-specific anatomical entity; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-16; rrf-3; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like/link domain superfamily; and PAN-3 domain. WB:WBGene00012501 Y26D4A.3 Predicted to be located in membrane. WB:WBGene00012502 clec-107 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; C-type lectin-like/link domain superfamily; and PAN-3 domain. WB:WBGene00012503 Y26D4A.5 Predicted to be located in membrane. WB:WBGene00012504 clec-108 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; rrf-3; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00012505 pals-13 Enriched in intestine based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and csr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including allantoin; metformin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00012506 Y26D4A.9 No description available WB:WBGene00012507 Y26D4A.10 No description available WB:WBGene00012508 Y26D4A.11 No description available WB:WBGene00012509 Y26D4A.12 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00012511 Y26D4A.14 No description available WB:WBGene00012512 ekl-5 Enriched in ABplapapppp; ABprapapppp; germ line; intestine; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including glp-1; dpy-10; and pie-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by ten chemicals including bisphenol A; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00012513 Y26E6A.2 Enriched in GABAergic neurons; neurons; and sensory neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and let-60 based on tiling array; microarray; and RNA-seq studies. Is affected by Zidovudine and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00012514 Y26E6A.3 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human METTL26 (methyltransferase like 26). WB:WBGene00012515 Y26G10.1 Predicted to be located in membrane. WB:WBGene00012516 sqst-4 Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and protein kinase C binding activity. Predicted to be involved in aggrephagy; endosome organization; and mitophagy. Predicted to be located in aggresome and amphisome. WB:WBGene00012517 srbc-73 Is affected by cyc-1 based on microarray studies. Is affected by Chlorpyrifos and Sirolimus based on microarray studies. WB:WBGene00012518 comt-2 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Involved in innate immune response. Is an ortholog of human COMTD1 (catechol-O-methyltransferase domain containing 1). WB:WBGene00012519 Y32B12A.4 Is affected by several genes including daf-2; sir-2.1; and unc-30 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Tunicamycin; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00012520 Y32B12A.5 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by rsr-2 based on tiling array studies. Is affected by five chemicals including nanoparticle; silicon dioxide nanoparticle; and cadmium based on microarray studies. WB:WBGene00012521 Y32B12B.1 Predicted to be located in membrane. WB:WBGene00012522 Y32B12B.2 Predicted to enable histone binding activity. Predicted to be located in nucleus. WB:WBGene00012523 srbc-65 Predicted to be located in membrane. WB:WBGene00012524 Y32B12B.4 Predicted to be involved in negative regulation of vulval development. WB:WBGene00012525 Y32B12C.1 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Tunicamycin; Sodium Chloride; and tert-Butylhydroperoxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Smr domain; Smr domain superfamily; and Phosphorylation site. WB:WBGene00012526 Y32B12C.3 Enriched in AFD based on RNA-seq studies. Is affected by several genes including eat-2; nhr-49; and hpl-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00012527 set-22 Enriched in several structures, including ABalapppaa; AFD; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SET domain superfamily and SET domain. WB:WBGene00012528 pap-1 Predicted to enable RNA binding activity; ion binding activity; and poly(A) RNA polymerase activity. Predicted to be involved in mRNA polyadenylation. Predicted to be located in nucleus. Is an ortholog of human PAPOLB (poly(A) polymerase beta). WB:WBGene00012529 Y32F6A.4 Predicted to be located in membrane. WB:WBGene00012530 Y32F6A.5 Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human SCPEP1 (serine carboxypeptidase 1). WB:WBGene00012531 Y32F6B.1 Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including breast ductal carcinoma; gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of human SLCO3A1 (solute carrier organic anion transporter family member 3A1). WB:WBGene00012532 crp-1 Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including Cdc42 protein signal transduction; actin filament organization; and endocytosis. Located in recycling endosome and trans-Golgi network. Expressed in several structures, including excretory cell; pharyngeal-intestinal valve; rectal epithelium; socket cell; and vulva. WB:WBGene00012533 fbxa-209 Enriched in ASER; OLL; PLM; PVD; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including stavudine; antimycin; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00012534 Y37A1A.1 No description available WB:WBGene00012535 Y37A1A.2 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00012536 Y37A1A.3 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. Is an ortholog of several human genes including SLC2A11 (solute carrier family 2 member 11); SLC2A5 (solute carrier family 2 member 5); and SLC2A9 (solute carrier family 2 member 9). WB:WBGene00012537 Y37A1B.4 Is affected by several genes including daf-2; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. WB:WBGene00012538 semo-1 Enables methanethiol oxidase activity. Expressed in hypodermal cell. Human ortholog(s) of this gene implicated in glaucoma. Is an ortholog of human SELENBP1 (selenium binding protein 1). WB:WBGene00012540 Y37A1B.7 Enriched in several structures, including germline precursor cell; intestine; rectal epithelial cell; sensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including methylmercury hydroxide; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00012541 irld-55 Enriched in CANL; CANR; neurons; and rect_D based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including sir-2.1; drh-3; and spn-4 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domain: Receptor L-domain superfamily. WB:WBGene00012542 irld-56 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and alg-1 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00012543 nkcc-1 Predicted to enable sodium:potassium:chloride symporter activity. Predicted to be involved in cell volume homeostasis; inorganic ion homeostasis; and monoatomic ion transmembrane transport. Predicted to be located in membrane. Expressed in body wall musculature; intestine; neurons; oocyte; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant nonsyndromic deafness 78; middle cerebral artery infarction; and renal tubular transport disease (multiple). Is an ortholog of human SLC12A1 (solute carrier family 12 member 1) and SLC12A2 (solute carrier family 12 member 2). WB:WBGene00012544 Y37D8A.2 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid catabolic process. Predicted to be located in extracellular region. Is an ortholog of human PLBD2 (phospholipase B domain containing 2). WB:WBGene00012545 Y37D8A.3 Enriched in several structures, including NSM; arc ant V; cephalic sheath cell; intestine; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; RNA-seq; and microarray studies. Is affected by fifteen chemicals including mianserin; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like. WB:WBGene00012546 Y37D8A.4 Enriched in several structures, including AFD; germ line; germline precursor cell; intestine; and lateral ganglion based on RNA-seq; single-cell RNA-seq; proteomic; and microarray studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including Heme; rotenone; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SH2 domain and SH2 domain superfamily. WB:WBGene00012547 Y37D8A.5 Predicted to be located in membrane. WB:WBGene00012548 Y37D8A.6 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00012549 Y37D8A.8 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00012550 spcs-2 Involved in IRE1-mediated unfolded protein response. Located in sarcoplasmic reticulum. Used to study Parkinson's disease. Is an ortholog of human SPCS2 (signal peptidase complex subunit 2). WB:WBGene00012551 cec-7 Predicted to be involved in chromatin organization and regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Is an ortholog of human MORF4L1 (mortality factor 4 like 1). WB:WBGene00012552 enu-3.5 Predicted to be involved in axon extension involved in axon guidance. Predicted to be located in neuronal cell body. WB:WBGene00012553 cox-5A Predicted to enable metal ion binding activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX5A (cytochrome c oxidase subunit 5A). WB:WBGene00012554 Y37D8A.16 Predicted to be located in membrane. WB:WBGene00012555 npp-25 Predicted to be involved in endoplasmic reticulum tubular network organization and membrane organization. Predicted to be located in endoplasmic reticulum. Is an ortholog of human TMEM33 (transmembrane protein 33). WB:WBGene00012556 mrps-10 Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS10 (mitochondrial ribosomal protein S10). WB:WBGene00012557 Y37D8A.19 Enriched in AVK; anterior spermatheca; germ line; and posterior spermatheca based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; RNA-seq; proteomic; and tiling array studies. Is affected by fifteen chemicals including Heme; hydrogen sulfide; and Ethanol based on microarray and RNA-seq studies. WB:WBGene00012558 rbm-7 Predicted to enable single-stranded RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Is an ortholog of human RBM7 (RNA binding motif protein 7). WB:WBGene00012559 epg-3 Involved in macroautophagy and negative regulation of autophagosome assembly. Located in cytoplasm. Expressed in body wall musculature and pharyngeal muscle cell. Is an ortholog of human VMP1 (vacuole membrane protein 1). WB:WBGene00012560 Y37D8A.25 Enriched in AFD; MSpaaapa; germ line; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including pgl-1; alg-1; and gld-2 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including hydrogen sulfide; Zidovudine; and Rifampin based on microarray and RNA-seq studies. Human PHETA1 enables protein homodimerization activity. Is predicted to encode a protein with the following domains: PH-like domain superfamily; Pleckstrin homology domain; PH domain containing protein Boi1/Boi2-like; and PH domain. Is an ortholog of human PHETA1 (PH domain containing endocytic trafficking adaptor 1); PHETA2 (PH domain containing endocytic trafficking adaptor 2); and PLEKHJ1 (pleckstrin homology domain containing J1). WB:WBGene00012561 Y37D8A.26 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00012562 Y37H2A.1 Predicted to enable hydrolase activity, acting on ester bonds. Is an ortholog of human TATDN2 (TatD DNase domain containing 2). WB:WBGene00012563 Y37H2A.3 No description available WB:WBGene00012564 fbxa-107 Enriched in ADEL; ADER; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including manganese chloride; mianserin; and Zidovudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00012565 fbxa-210 Enriched in several structures, including BDU; cholinergic neurons; germ line; head mesodermal cell; and touch receptor neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including manganese chloride; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00012566 fbxa-211 Enriched in several structures, including ABplapapppp; ABprapapppp; FLP; germ line; and head mesodermal cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00012567 Y37H2A.7 Enriched in AFD and germline precursor cell based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and elt-2 based on microarray and RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00012568 fbxa-212 Enriched in I5 neuron; cholinergic neurons; germ line; head mesodermal cell; and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by five chemicals including manganese chloride; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00012569 fbxc-46 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00012570 Y37H2A.10 Predicted to be located in membrane. WB:WBGene00012571 Y37H2A.11 Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including eat-2; lin-35; and nhr-49 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including aldicarb; hydrogen sulfide; and methylmercuric chloride based on microarray studies. WB:WBGene00012572 Y37H2B.1 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Tunicamycin; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00012573 Y37H2C.1 Enriched in GABAergic neurons; OLL; PVD; dopaminergic neurons; and pharyngeal-intestinal valve based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; Zidovudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00012574 fbxa-213 Enriched in neurons based on RNA-seq studies. Is affected by several genes including clk-1; hpl-2; and etr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by dibromoacetic acid; tetrabromobisphenol A; and adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00012575 Y37H2C.4 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00012576 Y37H9A.1 Enriched in germ line; intestine; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; let-60; and hsf-1 based on RNA-seq; microarray; and proteomic studies. Is affected by Doxycycline; Humic Substances; and Sirolimus based on proteomic and microarray studies. WB:WBGene00012577 Y37H9A.2 Is affected by several genes including daf-2; elt-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00012578 ccct-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 3. Is an ortholog of human CC2D1B (coiled-coil and C2 domain containing 1B). WB:WBGene00012579 Y38E10A.1 Is affected by cyc-1 and rsr-2 based on microarray and tiling array studies. Is affected by Chlorpyrifos and Diazinon based on microarray studies. WB:WBGene00012580 Y38E10A.2 Enriched in ciliated neurons and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by drh-3; csr-1; and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00012581 Y38E10A.3 Enriched in AVG; F cell; U cell; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including diallyl trisulfide; Tunicamycin; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00012582 clec-8 Enriched in AFD and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00012583 clec-4 Acts upstream of or within with a positive effect on feeding behavior. Expressed in amphid neurons; int1DL; int1DR; int1VL; and int1VR. WB:WBGene00012584 ceh-100 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in brain development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed widely. WB:WBGene00012585 lips-15 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00012586 Y38E10A.8 Predicted to enable eukaryotic translation initiation factor 2alpha kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Wolcott-Rallison syndrome; and hepatitis B. Is an ortholog of human EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) and EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3). WB:WBGene00012587 Y38E10A.9 Enriched in AFDL; AFDR; GABAergic neurons; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including Tunicamycin; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1412) and Protein of unknown function DUF1412. WB:WBGene00012588 lips-16 Enriched in excretory cell and neurons based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; rotenone; and stavudine based on microarray and RNA-seq studies. WB:WBGene00012589 nspe-4 Enriched in ADEshL; ADEshR; germline precursor cell; and neurons based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1412) and Protein of unknown function DUF1412. WB:WBGene00012590 nspe-3 Enriched in body wall muscle cell; germline precursor cell; and intestine based on tiling array and microarray studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1412) and Protein of unknown function DUF1412. WB:WBGene00012591 nspe-1 Enriched in AINL; AINR; PLM; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty-five chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1412) and Protein of unknown function DUF1412. WB:WBGene00012592 Y38E10A.14 Enriched in several structures, including ABplppppaa; ABprppppaa; PLM; germ line; and gonadal sheath cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-eight chemicals including hydrogen sulfide; Rifampin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00012593 nspe-7 Enriched in AFD; PLM; hypodermis; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-eight chemicals including hydrogen sulfide; tryptophan; and bisphenol A based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1412) and Protein of unknown function DUF1412. WB:WBGene00012594 nspe-5 Enriched in hypodermis based on tiling array studies. Is affected by several genes including daf-2; sir-2.1; and dpy-7 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1412) and Protein of unknown function DUF1412. WB:WBGene00012595 Y38E10A.17 Enriched in G2; W cell; germ line; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-seven chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012596 nhr-234 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00012597 nhr-235 Predicted to be located in nucleus. Expressed in neurons. WB:WBGene00012600 Y38E10A.22 Predicted to enable adenyl-nucleotide exchange factor activity. Predicted to be located in endoplasmic reticulum. WB:WBGene00012602 Y38E10A.24 Enriched in neurons and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including aldicarb; hydrogen sulfide; and rotenone based on microarray and RNA-seq studies. WB:WBGene00012603 nspe-6 Enriched in arcade cell; pharyngeal-intestinal valve cell; and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; Tunicamycin; and 4-bromodiphenyl ether based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1412) and Protein of unknown function DUF1412. WB:WBGene00012604 nspe-2 Enriched in several structures, including MSaapapa; MSpapapa; arcade cell; germline precursor cell; and pharyngeal-intestinal valve cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by thirty-two chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1412) and Protein of unknown function DUF1412. WB:WBGene00012605 Y38F1A.1 Enriched in several structures, including germ line; head mesodermal cell; muscle cell; sperm; and touch receptor neurons based on proteomic; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including nicotinic acid; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00012606 Y38F1A.2 Predicted to enable metal ion binding activity and ubiquitin protein ligase activity. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal dominant sensory ataxia 1 and hereditary spastic paraplegia 85. Is an ortholog of human RNF170 (ring finger protein 170). WB:WBGene00012607 Y38F1A.4 Predicted to be located in membrane. WB:WBGene00012608 hphd-1 Predicted to enable alcohol dehydrogenase (NAD+) activity and hydroxyacid-oxoacid transhydrogenase activity. Predicted to be involved in glutamate catabolic process via 2-oxoglutarate. Predicted to be located in mitochondrion. Is an ortholog of human ADHFE1 (alcohol dehydrogenase iron containing 1). WB:WBGene00012609 Y38F1A.7 Predicted to be located in membrane. WB:WBGene00012610 Y38F1A.8 Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00012612 Y38H6A.1 Is affected by rsr-2; sir-2.1; and eat-2 based on tiling array and microarray studies. Is affected by procyanidin; Hydrolyzable Tannins; and Sirolimus based on microarray studies. WB:WBGene00012614 Y38H6A.3 Enriched in AMshL; AMshR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including Tunicamycin; Sirolimus; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Cysteine-rich repeat. WB:WBGene00012615 dct-16 Enriched in several structures, including ABplapaaap; ABprapaaap; MSaaaaapa; head mesodermal cell; and neurons based on tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including Cyclosporine; dimedone; and rotenone based on proteomic; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00012616 dct-14 Predicted to be involved in receptor localization to non-motile cilium. Predicted to be part of BBSome. WB:WBGene00012617 Y38H6C.4 Enriched in AFD; AWCL; AWCR; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; let-60; and eat-2 based on tiling array and microarray studies. Is affected by Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00012618 dct-10 Enriched in neurons and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Alovudine; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00012619 Y38H6C.6 No description available WB:WBGene00012620 Y38H6C.7 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by several genes including eat-2; pgl-1; and lin-15B based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00012621 Y38H6C.8 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; autoimmune disease (multiple); and cholangiocarcinoma. Is an ortholog of human REG1A (regenerating family member 1 alpha); REG1B (regenerating family member 1 beta); and REG3G (regenerating family member 3 gamma). WB:WBGene00012622 Y38H6C.9 Enriched in neurons and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00012623 fbxa-149 Enriched in NSM; RID; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00012624 fbxa-150 Involved in innate immune response. WB:WBGene00012625 Y38H6C.13 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and prg-1 based on tiling array; RNA-seq; and microarray studies. Is affected by allantoin based on microarray studies. Is predicted to encode a protein with the following domains: F-box protein she-1-like and F-box domain. WB:WBGene00012626 famh-161 Predicted to be involved in cilium organization. Located in axoneme; ciliary base; and ciliary transition zone. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in retinitis pigmentosa 28. Is an ortholog of human FAM161B (FAM161 centrosomal protein B). WB:WBGene00012627 Y38H6C.15 Predicted to be located in membrane. WB:WBGene00012628 Y38H6C.16 Predicted to be located in membrane. WB:WBGene00012629 slc-36.3 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in vacuolar membrane. Human ortholog(s) of this gene implicated in iminoglycinuria. Is an ortholog of several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A4 (solute carrier family 36 member 4). WB:WBGene00012630 Y38H6C.18 Is affected by several genes including clk-1; csr-1; and daf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by Rifampin; Sirolimus; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012631 vmo-1 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00012632 Y38H6C.20 Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. WB:WBGene00012633 Y38H6C.21 Predicted to be located in membrane. WB:WBGene00012634 Y38H6C.23 Enriched in OLL; PVD; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including 1-methylnicotinamide; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00012635 Y38H8A.1 Predicted to be located in membrane. WB:WBGene00012636 Y38H8A.2 Predicted to enable metal ion binding activity. WB:WBGene00012637 ttbk-8.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00012638 Y38H8A.4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cellular response to glucose starvation; intracellular signal transduction; and negative regulation of TOR signaling. Predicted to be part of nucleotide-activated protein kinase complex. Is an ortholog of several human genes including TSSK1B (testis specific serine kinase 1B); TSSK2 (testis specific serine kinase 2); and TSSK3 (testis specific serine kinase 3). WB:WBGene00012639 fezf-1 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 22 with or without anosmia. Is an ortholog of human FEZF1 (FEZ family zinc finger 1). WB:WBGene00012640 Y38H8A.7 Enriched in germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00012641 epg-6 Enables phosphatidylinositol phosphate binding activity. Involved in autophagosome assembly. Located in cytoplasm. Expressed widely. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation 5. Is an ortholog of human WDR45 (WD repeat domain 45). WB:WBGene00012642 Y39A1A.2 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00012643 Y39A1A.3 Enriched in AFD; NSM; germ line; intestine; and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; proteomic; RNA-seq; and microarray studies. Is affected by six chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Sjoegren syndrome/scleroderma autoantigen 1 and Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27). Is an ortholog of human ZNRD2 (zinc ribbon domain containing 2). WB:WBGene00012644 rabx-5 Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in endosomal vesicle fusion and molting cycle. Located in early endosome. Expressed in several structures, including coelomocyte; distal tip cell; neurons; ventral nerve cord; and vulva. Is an ortholog of human RABGEF1 (RAB guanine nucleotide exchange factor 1). WB:WBGene00012645 mrpl-22 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL22 (mitochondrial ribosomal protein L22). WB:WBGene00012646 lron-10 Enriched in several structures, including arcade cell; germ line; head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including gld-1; sir-2.1; and aak-2 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00012647 swt-4 Predicted to enable sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport. Predicted to be located in Golgi membrane and plasma membrane. Is an ortholog of human SLC50A1 (solute carrier family 50 member 1). WB:WBGene00012648 Y39A1A.9 Predicted to be involved in female meiosis I; mRNA stabilization; and male meiosis I. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human MEIOC (meiosis specific with coiled-coil domain). WB:WBGene00012649 Y39A1A.10 Is affected by several genes including daf-12; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by multi-walled carbon nanotube and cadmium based on RNA-seq and microarray studies. WB:WBGene00012650 orc-1 Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA binding activity. Predicted to be involved in DNA replication initiation and mitotic DNA replication checkpoint signaling. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 1. Is an ortholog of human ORC1 (origin recognition complex subunit 1). WB:WBGene00012651 orc-4 Predicted to enable DNA replication origin binding activity. Predicted to be involved in DNA replication initiation. Predicted to be located in nucleus. Predicted to be part of nuclear origin of replication recognition complex. WB:WBGene00012652 emg-1 Predicted to enable rRNA (pseudouridine) methyltransferase activity and rRNA binding activity. Predicted to be involved in rRNA base methylation. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Human ortholog(s) of this gene implicated in Bowen-Conradi syndrome. Is an ortholog of human EMG1 (EMG1 N1-specific pseudouridine methyltransferase). WB:WBGene00012653 C12C8.t2 No description available WB:WBGene00012654 Y39A1A.16 Enriched in ABalapppaa and AVL based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00012655 Y39A1A.17 Is affected by several genes including eat-2; sir-2.1; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00012656 Y39A1A.18 Enriched in ABplpapppa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pmk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00012657 Y39A1A.20 Predicted to be located in membrane. WB:WBGene00012658 Y39A1A.21 Enables protein-lysine N-methyltransferase activity. Involved in regulation of mitochondrial ATP synthesis coupled proton transport. Predicted to be located in mitochondrion. Is an ortholog of human ATPSCKMT (ATP synthase c subunit lysine N-methyltransferase). WB:WBGene00012659 Y39A1A.22 Predicted to enable inositol hexakisphosphate binding activity and phosphate ion transmembrane transporter activity. Predicted to be involved in cellular response to phosphate starvation and phosphate ion transport. Predicted to be located in Golgi apparatus and plasma membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Is an ortholog of human XPR1 (xenotropic and polytropic retrovirus receptor 1). WB:WBGene00012660 Y39A1A.24 Enriched in body wall musculature; neurons; and retrovesicular ganglion based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; age-1; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including mianserin; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012661 clec-163 Is affected by several genes including eat-2; npr-1; and nhr-49 based on microarray; RNA-seq; and tiling array studies. Is affected by six chemicals including Mercuric Chloride; Tunicamycin; and tert-Butylhydroperoxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; C-type lectin-like; von Willebrand factor A-like domain superfamily; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and Phosphorylation site. WB:WBGene00012662 Y39A1C.1 Located in striated muscle dense body. Expressed in nerve ring. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 6 and sensorineural hearing loss. Is an ortholog of human TMIE (transmembrane inner ear). WB:WBGene00012663 hex-3 Enables beta-N-acetylgalactosaminidase activity. Involved in polysaccharide metabolic process. Predicted to be located in membrane. Expressed in intestine. Is an ortholog of human HEXD (hexosaminidase D). WB:WBGene00012664 Y39B6A.1 Predicted to be located in nucleolus and nucleoplasm. WB:WBGene00012665 pph-5 Enables Hsp90 protein binding activity and phosphoprotein phosphatase activity. Involved in negative regulation of exocytosis and protein localization to organelle. Located in cytoplasm; mitotic spindle; and protein-containing complex. Expressed in several structures, including touch receptor neurons. Is an ortholog of human PPP5C (protein phosphatase 5 catalytic subunit). WB:WBGene00012666 Y39B6A.3 Predicted to enable 2 iron, 2 sulfur cluster binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 5. Is an ortholog of human ISCA1 (iron-sulfur cluster assembly 1). WB:WBGene00012668 Y39B6A.5 Enriched in several structures, including coelomocyte; head mesodermal cell; rectal gland cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and elt-2 based on RNA-seq; microarray; and tiling array studies. Is affected by sixteen chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00012669 Y39B6A.7 Predicted to enable hydrolase activity. Predicted to be involved in lipid metabolic process. WB:WBGene00012670 cpg-23 Enriched in IL socket cell; arc ant V; neurons; and seam cell based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Cysteine-rich repeat. WB:WBGene00012671 Y39B6A.9 Expressed in spicule protractor muscle and spicule retractor muscle. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012672 Y39B6A.10 Predicted to be located in membrane. WB:WBGene00012673 dyf-17 Located in ciliary transition zone. Expressed in nervous system. WB:WBGene00012674 bed-1 Predicted to enable DNA binding activity and metal ion binding activity. WB:WBGene00012675 Y39B6A.13 Enriched in AFD; body wall muscle cell; germ line; germline precursor cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00012676 pro-3 Predicted to be involved in ribosomal large subunit biogenesis and ribosomal large subunit export from nucleus. Predicted to be located in nucleolus. Is an ortholog of human SDAD1 (SDA1 domain containing 1). WB:WBGene00012678 zhp-4 Predicted to enable SUMO transferase activity. Predicted to be involved in homologous chromosome pairing at meiosis and protein sumoylation. Predicted to be located in synaptonemal complex. Human ortholog(s) of this gene implicated in spermatogenic failure 62. Is an ortholog of human RNF212 (ring finger protein 212). WB:WBGene00012679 Y39B6A.18 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on RNA-seq; tiling array; and microarray studies. Is affected by ten chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00012680 Y39B6A.21 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including 1-methylnicotinamide; rotenone; and D-glucopyranose based on RNA-seq and microarray studies. WB:WBGene00012681 asp-15 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human REN (renin). WB:WBGene00012682 asp-16 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human PGC (progastricsin) and REN (renin). WB:WBGene00012683 asp-17 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Is an ortholog of several human genes including CTSE (cathepsin E); PGA3 (pepsinogen A3); and PGA5 (pepsinogen A5). WB:WBGene00012684 Y39B6A.25 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Tudor domain and RING finger protein 17. WB:WBGene00012686 Y39B6A.27 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00012688 Y39B6A.29 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00012689 Y39B6A.30 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00012690 Y39B6A.31 Enriched in intestine and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; manganese chloride; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00012692 Y39B6A.33 Predicted to enable 5S rRNA binding activity. Involved in positive regulation of cellular respiration. Located in nucleolus. Is an ortholog of human NOP53 (NOP53 ribosome biogenesis factor). WB:WBGene00012693 Y39B6A.34 Predicted to be involved in intrinsic apoptotic signaling pathway. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COA8 (cytochrome c oxidase assembly factor 8). WB:WBGene00012694 gtf-2F2 Predicted to enable DNA binding activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIF complex. Is an ortholog of human GTF2F2 (general transcription factor IIF subunit 2). WB:WBGene00012695 Y39B6A.37 Enriched in several structures, including ABalappaap; AFD; germ line; intestine; and rectal muscle based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including hsf-1; sir-2.1; and npr-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including rotenone; mianserin; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012696 reps-1 Expressed in excretory secretory system; intestine; muscle cell; somatic nervous system; and vulva. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation. Human REPS1 enables SH3 domain binding activity. Is predicted to encode a protein with the following domains: Cytoskeletal-regulatory complex EF hand; EH domain; EF-hand domain pair; and Phosphorylation site. Is an ortholog of human REPS1 (RALBP1 associated Eps domain containing 1) and REPS2 (RALBP1 associated Eps domain containing 2). WB:WBGene00012697 mrps-35 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS35 (mitochondrial ribosomal protein S35). WB:WBGene00012698 sws-1 Predicted to enable zinc ion binding activity. Predicted to be involved in double-strand break repair via homologous recombination. Predicted to be part of Shu complex. Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis and spermatogenic failure. Is an ortholog of human ZSWIM7 (zinc finger SWIM-type containing 7). WB:WBGene00012699 Y39B6A.41 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00012700 Y39B6A.42 Enriched in several structures, including AIZ; g2; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012701 Y39B6A.43 Predicted to be part of DNA-directed RNA polymerase complex. WB:WBGene00012702 ztf-20 Is affected by several genes including daf-2; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including stavudine; Zidovudine; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00012703 nhr-145 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00012704 mlt-3 Involved in ecdysis, collagen and cuticulin-based cuticle. Predicted to be located in cilium. Expressed in hyp7 syncytium. Is an ortholog of human ANKS3 (ankyrin repeat and sterile alpha motif domain containing 3). WB:WBGene00012705 sre-18 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00012706 sre-17 Is affected by vhl-1 based on microarray studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00012707 sre-16 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head. WB:WBGene00012708 sre-19 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00012709 sre-15 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00012710 Y39C12A.9 Enriched in ABplpppppp; ABprpppppp; muscle cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; pgl-1; and aak-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Chaperone J-domain superfamily. WB:WBGene00012711 Y39E4A.1 Predicted to be located in membrane. WB:WBGene00012712 ttm-1 Predicted to enable zinc ion transmembrane transporter activity. Involved in response to cadmium ion and response to nematicide. Predicted to be located in plasma membrane. Expressed in head neurons; hypodermis; seam cell; and vulva. Human ortholog(s) of this gene implicated in prostate carcinoma in situ. Is an ortholog of human SLC30A3 (solute carrier family 30 member 3) and SLC30A4 (solute carrier family 30 member 4). WB:WBGene00012713 bckd-1A Predicted to enable 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity and metal ion binding activity. Predicted to be involved in branched-chain amino acid catabolic process. Predicted to be located in mitochondrial matrix. Predicted to be part of mitochondrial alpha-ketoglutarate dehydrogenase complex. Human ortholog(s) of this gene implicated in maple syrup urine disease. Is an ortholog of human BCKDHA (branched chain keto acid dehydrogenase E1 subunit alpha). WB:WBGene00012714 abce-1 Predicted to enable ATP binding activity; iron ion binding activity; and ribosomal small subunit binding activity. Predicted to be involved in ribosomal subunit export from nucleus; translational initiation; and translational termination. Expressed in several structures, including muscle cell; neurons; and vulva. Human ortholog(s) of this gene implicated in breast carcinoma; carcinoma (multiple); and human immunodeficiency virus infectious disease. Is an ortholog of human ABCE1 (ATP binding cassette subfamily E member 1). WB:WBGene00012715 snpc-1.2 Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be part of snRNA-activating protein complex. Is an ortholog of human SNAPC1 (small nuclear RNA activating complex polypeptide 1). WB:WBGene00012716 Y39E4B.5 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00012717 Y39E4B.6 Predicted to enable 7SK snRNA binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleoplasm. WB:WBGene00012718 dhhc-8 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Is an ortholog of human ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5) and ZDHHC8 (zinc finger DHHC-type palmitoyltransferase 8). WB:WBGene00012719 Y39E4B.10 Enriched in several structures, including ABalpapaap; ABarappaap; PVR; amphid neurons; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; isp-1; and atfs-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00012720 Y39E4B.11 Enriched in several structures, including ABalppppppa; ABalppppppp; ABplaapappp; ABpraaapppa; and ABpraaapppp based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00012721 Y39E4B.13 Predicted to be located in membrane. WB:WBGene00012722 Y39G8B.1 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including acute lymphoblastic leukemia (multiple); artery disease (multiple); and carcinoma (multiple). Is an ortholog of human AKR1B1 (aldo-keto reductase family 1 member B); AKR1B10 (aldo-keto reductase family 1 member B10); and AKR1B15 (aldo-keto reductase family 1 member B15). WB:WBGene00012723 Y39G8B.2 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including acute lymphoblastic leukemia (multiple); castration-resistant prostate carcinoma; and ductal carcinoma in situ. Is an ortholog of human AKR1B15 (aldo-keto reductase family 1 member B15). WB:WBGene00012724 sre-48 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00012725 sre-47 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head. WB:WBGene00012726 Y39G8B.5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00012727 Y39G8B.7 Enriched in OLL; PVD; intestine; and male-specific anatomical entity based on microarray and tiling array studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Heme; Tunicamycin; and TPEN based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00012728 Y39G8B.9 Enriched in head mesodermal cell; intestine; pharyngeal muscle cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; tiling array; microarray; and proteomic studies. Is affected by nineteen chemicals including 1-methylnicotinamide; nicotinic acid; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00012729 Y39G8B.10 Enriched in head mesodermal cell and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00012730 xrn-1 Predicted to enable 5'-3' RNA exonuclease activity and RNA binding activity. Involved in determination of adult lifespan and negative regulation of cytoplasmic mRNA processing body assembly. Predicted to be located in nucleus. Expressed in hypodermis and rectum. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human XRN1 (5'-3' exoribonuclease 1). WB:WBGene00012731 Y39G8C.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00012732 wac-1.2 Enriched in several structures, including ABalappaap; ABplapappp; ABplapppaa; ABprapppaa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including rotenone; stavudine; and Rifampin based on RNA-seq studies. Human ortholog(s) of this gene implicated in DeSanto-Shinawi syndrome. Human WAC enables RNA polymerase II complex binding activity and chromatin binding activity. Is predicted to encode a protein with the following domains: WW domain superfamily and WW domain. Is an ortholog of human WAC (WW domain containing adaptor with coiled-coil). WB:WBGene00012734 wac-1.1 Predicted to enable RNA polymerase II complex binding activity and chromatin binding activity. Predicted to be involved in positive regulation of TORC1 signaling and regulation of autophagy. Predicted to be located in nucleus. WB:WBGene00012735 sptf-3 Enables DNA-binding transcription factor activity, RNA polymerase II-specific and chromatin binding activity. Involved in several processes, including generation of neurons; nematode larval development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including MSpaa; hypodermal cell; intestine; pharyngeal cell; and somatic nervous system. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Is an ortholog of human SP1 (Sp1 transcription factor); SP3 (Sp3 transcription factor); and SP4 (Sp4 transcription factor). WB:WBGene00012738 eif-3.J Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Is an ortholog of human EIF3J (eukaryotic translation initiation factor 3 subunit J). WB:WBGene00012739 Y40B1B.7 Located in nucleolus. Expressed in ventral nerve cord. Is an ortholog of human CCDC86 (coiled-coil domain containing 86). WB:WBGene00012740 slc-25A46 Predicted to be involved in mitochondrial fission. Predicted to be located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1E. Is an ortholog of human SLC25A46 (solute carrier family 25 member 46). WB:WBGene00012741 Y40H4A.2 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00012742 Y40H7A.2 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00012743 Y40H7A.3 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00012744 Y40H7A.4 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00012745 Y40H7A.7 Is affected by several genes including daf-16; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00012746 Y40H7A.9 Enriched in DA neuron; NSM; VA neuron; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube and resveratrol based on RNA-seq and microarray studies. WB:WBGene00012747 Y40H7A.10 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSO (cathepsin O). WB:WBGene00012748 Y40H7A.11 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00012749 Y41C4A.1 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00012750 faah-6 Predicted to enable amidase activity and fatty acid amide hydrolase activity. Predicted to be involved in fatty acid catabolic process. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Is an ortholog of human FAAH (fatty acid amide hydrolase). WB:WBGene00012752 C12C8.t3 No description available WB:WBGene00012753 Y41C4A.6 Enriched in neurons and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00012754 Y41C4A.7 Enriched in ASG; AVK; NSM; somatic gonad precursor; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Immunoglobulin-like fold and PapD-like superfamily. WB:WBGene00012755 Y41C4A.8 Involved in innate immune response. Predicted to be located in cytoplasm. Is an ortholog of human TP53I13 (tumor protein p53 inducible protein 13). WB:WBGene00012756 Y41C4A.9 Predicted to enable U3 snoRNA binding activity and rRNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human UTP25 (UTP25 small subunit processome component). WB:WBGene00012757 Y41C4A.11 Predicted to enable zinc ion binding activity. Involved in endoplasmic reticulum unfolded protein response. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in lysosomal membrane. Expressed in pharynx. WB:WBGene00012758 Y41C4A.12 Enriched in several structures, including ABplppppaa; ABprppppaa; arcade cell; excretory system; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00012759 sup-1 Located in neuron projection; neuronal cell body membrane; and synapse. Expressed in body wall musculature; neurons; and ventral nerve cord. WB:WBGene00012760 Y41C4A.17 Enriched in neurons and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and elt-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including hydrogen sulfide; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00012761 Y41C4A.18 Predicted to be located in membrane. WB:WBGene00012762 Y41E3.1 Predicted to be located in membrane. WB:WBGene00012763 atln-2 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in endoplasmic reticulum organization and protein homooligomerization. Predicted to be located in membrane. Expressed in head neurons. WB:WBGene00012764 Y41E3.6 Enriched in body wall muscle cell from C lineage; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and mdt-15 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4440; Domain of unknown function (DUF4440); and NTF2-like domain superfamily. WB:WBGene00012765 Y41E3.7 Predicted to enable fatty-acyl-CoA binding activity. Predicted to be located in Golgi membrane. Is an ortholog of human ACBD3 (acyl-CoA binding domain containing 3). WB:WBGene00012766 Y41E3.8 Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in Golgi apparatus and endoplasmic reticulum membrane. Is an ortholog of human SELENOK (selenoprotein K). WB:WBGene00012767 fcd-2 Predicted to enable DNA polymerase binding activity. Involved in nucleotide-excision repair and regulation of DNA-templated DNA replication. Located in nucleus. Expressed in germ line. Used to study Fanconi anemia. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group D2; breast cancer; and skin melanoma. Is an ortholog of human FANCD2 (FA complementation group D2). WB:WBGene00012768 eef-1B.2 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in translational elongation. Predicted to be located in cytosol. Is an ortholog of human EEF1B2 (eukaryotic translation elongation factor 1 beta 2). WB:WBGene00012769 hrpu-1 Enriched in several structures, including AVE; germ line; mechanosensory neurons; rectal epithelial cell; and rectum based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including aldicarb; rotenone; and Cry5B based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in colorectal cancer and developmental and epileptic encephalopathy 54. Human HNRNPU enables several functions, including ATP binding activity; basal RNA polymerase II transcription machinery binding activity; and nucleic acid binding activity. Is predicted to encode a protein with the following domains: P-loop containing nucleoside triphosphate hydrolase; SPRY domain; B30.2/SPRY domain superfamily; AAA domain; and Concanavalin A-like lectin/glucanase domain superfamily. Is an ortholog of human HNRNPU (heterogeneous nuclear ribonucleoprotein U) and HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U like 2). WB:WBGene00012770 srt-47 Predicted to be located in membrane. Expressed in AWC-OFF and head neurons. WB:WBGene00012771 Y41E3.13 Is affected by several genes including clk-1; met-2; and smgl-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00012772 srt-49 Predicted to be located in membrane. WB:WBGene00012773 srt-48 Predicted to be located in membrane. WB:WBGene00012775 srt-50 Predicted to be located in membrane. WB:WBGene00012776 Y42A5A.1 Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human TRHDE (thyrotropin releasing hormone degrading enzyme). WB:WBGene00012777 lact-8 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; anterior hypodermis; and carbon dioxide sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including levamisole; allantoin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Beta-lactamase; Beta-lactamase/transpeptidase-like; and Beta-lactamase-related. WB:WBGene00012778 Y42A5A.3 Enriched in rectal gland cell and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including Mercuric Chloride; levamisole; and procyanidin based on microarray and RNA-seq studies. WB:WBGene00012779 cdkl-1 Predicted to enable protein serine/threonine kinase activity. Involved in non-motile cilium assembly and regulation of cilium assembly. Located in ciliary transition zone. Expressed in amphid neurons and phasmid neurons. Is an ortholog of human CDKL1 (cyclin dependent kinase like 1). WB:WBGene00012780 Y42A5A.5 Predicted to be involved in respiratory electron transport chain. Predicted to be located in mitochondrion. Is an ortholog of human ETFRF1 (electron transfer flavoprotein regulatory factor 1). WB:WBGene00012781 nspd-7 Enriched in intestine; sperm; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Caenorhabditis elegans protein of unknown function (DUF780) and Protein of unknown function DUF780, Caenorhabditis species. WB:WBGene00012782 Y43C5A.2 Predicted to be located in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); carcinoma (multiple); and congenital afibrinogenemia. Is an ortholog of human ANGPT1 (angiopoietin 1) and FGB (fibrinogen beta chain). WB:WBGene00012783 Y43C5A.3 Enables double-stranded DNA binding activity. Involved in defense response to Gram-negative bacterium and killing of cells of another organism. Expressed in hyp7 syncytium and ventral cord blast cell. WB:WBGene00012784 Y43C5A.4 Predicted to be located in membrane. WB:WBGene00012785 Y43C5B.2 Predicted to enable ATP binding activity and non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00012786 Y43C5B.3 Predicted to enable branched-chain amino acid transmembrane transporter activity. Predicted to be involved in branched-chain amino acid transport. Predicted to be located in mitochondrion. Is an ortholog of human SLC25A44 (solute carrier family 25 member 44). WB:WBGene00012787 Y43D4A.1 Predicted to enable symporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00012788 Y43D4A.2 Predicted to enable glucuronosyltransferase activity. Predicted to be located in membrane. WB:WBGene00012789 Y43D4A.3 Predicted to be located in membrane. WB:WBGene00012790 Y43D4A.4 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00012791 Y43D4A.5 Enriched in several structures, including AVK; arc ant V; male distal tip cell; sensory neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Heme; hydrogen sulfide; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00012792 Y43D4A.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CHEK1 (checkpoint kinase 1). WB:WBGene00012793 Y43D4A.7 Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nitroguanidine based on microarray studies. WB:WBGene00012794 Y43E12A.2 Predicted to enable metal ion binding activity. Located in mitochondrion. Is an ortholog of human ZCCHC24 (zinc finger CCHC-type containing 24). WB:WBGene00012795 Y43E12A.3 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including bisphenol S; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00012796 Y43F4A.1 Predicted to enable peptidase activity. Predicted to be involved in cell adhesion; cell division; and proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human LMLN (leishmanolysin like peptidase). WB:WBGene00012797 Y43F4A.2 No description available WB:WBGene00012798 Y43F4A.3 Expressed in head neurons and intestinal cell. WB:WBGene00012799 Y43F4A.4 Predicted to enable 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity. WB:WBGene00012801 Y43F4B.2 No description available WB:WBGene00012802 set-25 Predicted to enable double-stranded DNA binding activity and histone methyltransferase activity. Predicted to be involved in chromatin remodeling and methylation. Part of heterochromatin. Expressed in hypodermis; intestine; muscle cell; and neurons. WB:WBGene00012803 Y43F4B.5 Predicted to enable phosphopentomutase activity. Predicted to be involved in purine ribonucleoside salvage. Located in nucleus. Is an ortholog of human PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2 like 1). WB:WBGene00012804 slc-36.1 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in vacuolar membrane. Expressed in head and hypodermis. Human ortholog(s) of this gene implicated in iminoglycinuria. Is an ortholog of several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A4 (solute carrier family 36 member 4). WB:WBGene00012806 dph-7 Predicted to enable diphthine methylesterase activity. Predicted to be located in cytoplasm. Is an ortholog of human DPH7 (diphthamide biosynthesis 7). WB:WBGene00012807 Y43F4B.10 Predicted to be located in cytoplasm and nucleus. Is an ortholog of human CDK2AP1 (cyclin dependent kinase 2 associated protein 1) and CDK2AP2 (cyclin dependent kinase 2 associated protein 2). WB:WBGene00012808 Y43F8A.1 Enriched in neurons and pm8 based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including clk-1; lin-35; and atfs-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Mercuric Chloride; multi-walled carbon nanotube; and Cadmium Chloride based on microarray and RNA-seq studies. WB:WBGene00012809 Y43F8A.2 Enriched in I5 neuron; cholinergic neurons; germ line; retrovesicular ganglion; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-eight chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00012810 nceh-1 Predicted to enable carboxylic ester hydrolase activity. Predicted to be located in membrane. Is an ortholog of human AADAC (arylacetamide deacetylase); AADACL2 (arylacetamide deacetylase like 2); and NCEH1 (neutral cholesterol ester hydrolase 1). WB:WBGene00012811 slcr-46.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hereditary folate malabsorption. Is an ortholog of human SLC46A1 (solute carrier family 46 member 1). WB:WBGene00012812 Y43F8B.1 Enriched in MC neuron; head mesodermal cell; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on proteomic; RNA-seq; and microarray studies. Is affected by fifteen chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00012813 Y43F8B.2 Predicted to enable kinase regulator activity and protein kinase A binding activity. Involved in innate immune response. Located in striated muscle dense body. Expressed in several structures, including nerve ring; tail hypodermis; and ventral nerve cord. Is an ortholog of human GSKIP (GSK3B interacting protein). WB:WBGene00012814 Y43F8B.3 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00012815 phy-4 Contributes to peptidyl-proline 4-dioxygenase activity. Part of procollagen-proline 4-dioxygenase complex. Expressed in excretory duct; pharyngeal gland cell; and pharyngeal-intestinal valve. WB:WBGene00012816 scl-21 Predicted to be located in extracellular space. Is an ortholog of human CLEC18A (C-type lectin domain family 18 member A); CLEC18B (C-type lectin domain family 18 member B); and CLEC18C (C-type lectin domain family 18 member C). WB:WBGene00012817 Y43F8B.6 Is affected by hpl-2; srbc-48; and hlh-26 based on tiling array and RNA-seq studies. Is affected by adsorbable organic bromine compound and Sirolimus based on microarray studies. WB:WBGene00012818 Y43F8B.7 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABplpapapa; ABplpppaaa; and ABprpapapa based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00012819 Y43F8B.9 Enriched in several structures, including ABplapappp; ABprapappp; G2; W cell; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; rotenone; and bisphenol S based on microarray and RNA-seq studies. WB:WBGene00012820 Y43F8B.10 Predicted to be located in membrane. WB:WBGene00012821 Y43F8B.11 Enriched in PVT; body wall muscle cell; head mesodermal cell; and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; pgl-1; and hsp-6 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00012822 Y43F8B.12 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; bisphenol S; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00012823 Y43F8B.13 Enriched in I5 neuron; head mesodermal cell; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; age-1; and daf-12 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; Tunicamycin; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00012824 Y43F8B.14 Predicted to enable ATP binding activity and ATP-dependent chromatin remodeler activity. Predicted to be involved in chromatin remodeling. WB:WBGene00012825 Y43F8C.3 Enriched in intestine; male-specific anatomical entity; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; Tunicamycin; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00012826 dyf-19 Involved in non-motile cilium assembly. Located in ciliary basal body and dendrite. Expressed in ciliated neurons. Is an ortholog of human FBF1 (Fas binding factor 1). WB:WBGene00012827 Y43F8C.5 Enriched in NSM; marginal cell; sperm; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00012828 Y43F8C.6 Predicted to be part of MLL1 complex and NURF complex. Is an ortholog of human C17orf49 (chromosome 17 open reading frame 49). WB:WBGene00012829 Y43F8C.7 Predicted to be part of EMC complex. Is an ortholog of human EMC10 (ER membrane protein complex subunit 10). WB:WBGene00012830 mrps-28 Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 47. Is an ortholog of human MRPS28 (mitochondrial ribosomal protein S28). WB:WBGene00012831 Y43F8C.9 Enriched in arcade cell; pharyngeal-intestinal valve cell; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00012832 dmd-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including nematode male tail tip morphogenesis; neuron differentiation; and regulation of reproductive process. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in neuronal cell body. Expressed in several structures, including PHC; epithelial cell; gonad; ray neuron type A; and tail hypodermis. Is an ortholog of human DMRTB1 (DMRT like family B with proline rich C-terminal 1). WB:WBGene00012833 Y43F8C.11 Predicted to be involved in RNA transport and regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be located in late endosome and membrane. WB:WBGene00012834 Y43F8C.13 Predicted to enable hydrolase activity, hydrolyzing N-glycosyl compounds and metal ion binding activity. Predicted to be involved in nucleobase-containing compound metabolic process and organonitrogen compound metabolic process. WB:WBGene00012835 ani-3 Predicted to be involved in actomyosin contractile ring assembly; mitotic cytokinesis; and septin ring organization. Predicted to be located in actomyosin contractile ring. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Is an ortholog of human ANLN (anillin, actin binding protein). WB:WBGene00012836 Y43F8C.15 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including hpl-2; set-2; and cyc-1 based on microarray; tiling array; and RNA-seq studies. WB:WBGene00012837 Y43F8C.16 Enriched in several structures, including ABplapaaaa; ABplapaaapa; ABplapppaa; ABprapaaapa; and ABprapppaa based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00012838 Y43F8C.17 Enriched in ABplapaaaa; ABprapaaaa; neurons; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including clk-1; csr-1; and smg-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including aldicarb; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00012839 Y43F8C.18 Enriched in PLM based on RNA-seq studies. Is affected by several genes including clk-1; aak-2; and hpl-2 based on microarray and RNA-seq studies. Is affected by six chemicals including bisphenol A; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00012840 grsp-1 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including D-glucose; bisphenol A; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00012841 Y43F11A.1 Enriched in ADEshL; ADEshR; PVPL; PVPR; and pm8 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012844 Y43F11A.4 Is affected by several genes including daf-16; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by seven chemicals including aldicarb; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012845 set-24 Enriched in germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including manganese chloride; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SET domain superfamily; Domain of unknown function (DUF545); SET domain; and SPK domain. WB:WBGene00012846 srxa-14 Predicted to be located in membrane. Expressed in ADLL; ADLR; AIML; and AIMR. WB:WBGene00012847 srxa-15 Predicted to be located in membrane. WB:WBGene00012848 Y44A6B.3 Enriched in BDU and mechanosensory neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and unc-30 based on microarray; tiling array; and RNA-seq studies. Is affected by hydrogen sulfide; D-glucose; and Colistin based on microarray and RNA-seq studies. WB:WBGene00012849 ttr-13 Predicted to be located in cell surface and extracellular region. WB:WBGene00012850 Y44A6C.1 Enriched in several structures, including ABplapaaapa; ABprapaaapa; enteric muscle; head mesodermal cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; levamisole; and tert-Butylhydroperoxide based on microarray and RNA-seq studies. WB:WBGene00012851 Y44A6C.2 Enriched in several structures, including ABplapaaapa; ALN; BDU; rectal epithelium; and touch receptor neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; multi-walled carbon nanotube; and indole based on microarray and RNA-seq studies. WB:WBGene00012852 Y44A6D.1 Enriched in AVK; intestine; and sensory neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00012853 tpan-1 Enriched in head mesodermal cell; intestine; neurons; and retrovesicular ganglion based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on proteomic; microarray; and RNA-seq studies. Is affected by sixteen chemicals including rotenone; sesamin; and iron oxide nanoparticle based on RNA-seq; microarray; and proteomic studies. WB:WBGene00012854 Y44A6D.3 Expressed in body wall musculature. Is predicted to encode a protein with the following domain: Winged helix-like DNA-binding domain superfamily. WB:WBGene00012855 Y44A6D.5 Predicted to enable branched-chain-amino-acid transaminase activity. Predicted to be involved in leucine biosynthetic process and valine biosynthetic process. Predicted to be located in mitochondrion. Is an ortholog of human BCAT2 (branched chain amino acid transaminase 2). WB:WBGene00012856 Y44A6D.6 Predicted to be located in membrane. WB:WBGene00012857 pbo-5 Enables extracellular ligand-gated monoatomic ion channel activity. Involved in defecation; lipid transport involved in lipid storage; and positive regulation of multicellular organismal process. Predicted to be located in neuron projection and synapse. Expressed in RIFL; RIFR; RIS; and body wall musculature. WB:WBGene00012858 Y44F5A.1 Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Is an ortholog of human WDR55 (WD repeat domain 55). WB:WBGene00012859 Y45F3A.1 Enriched in cholinergic neurons; germ line; interneuron; retrovesicular ganglion; and in male based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; dpy-10; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including manganese chloride; mianserin; and stavudine based on RNA-seq and microarray studies. WB:WBGene00012860 acdh-11 Enables fatty acid binding activity. Involved in adaptive thermogenesis. Expressed in head. WB:WBGene00012861 Y45F3A.4 Enriched in several structures, including accessory cell; head mesodermal cell; hyp3; interfacial epithelial cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and sek-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eight chemicals including stavudine; Zidovudine; and antimycin based on RNA-seq and microarray studies. WB:WBGene00012862 Y45F3A.5 Is affected by several genes including clk-1; aak-2; and nhr-8 based on tiling array; microarray; and RNA-seq studies. Is affected by dafa#1 and allantoin based on microarray studies. WB:WBGene00012863 Y45F3A.8 Enriched in g1AL; g1AR; g1P; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00012864 Y45F3A.9 Predicted to enable rRNA (guanine) methyltransferase activity. Predicted to be involved in rRNA modification. Predicted to be located in mitochondrion. Is an ortholog of human MRM1 (mitochondrial rRNA methyltransferase 1). WB:WBGene00012866 afmd-2 Predicted to enable hydrolase activity. Predicted to be involved in tryptophan catabolic process to kynurenine. Predicted to be located in cytoplasm. Is an ortholog of human AFMID (arylformamidase). WB:WBGene00012867 seld-1 Predicted to enable selenide, water dikinase activity. Predicted to be involved in selenocysteine biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in colorectal adenoma and colorectal carcinoma. Is an ortholog of human SEPHS2 (selenophosphate synthetase 2). WB:WBGene00012868 tbc-9 Predicted to enable GTPase activator activity. Human ortholog(s) of this gene implicated in nephrotic syndrome type 20. Is an ortholog of several human genes including TBC1D8 (TBC1 domain family member 8); TBC1D9 (TBC1 domain family member 9); and TBC1D9B (TBC1 domain family member 9B). WB:WBGene00012869 Y45F10A.7 Predicted to be involved in intracellular signal transduction. WB:WBGene00012870 Y45F10B.2 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; Doxycycline; and paraquat based on microarray and RNA-seq studies. WB:WBGene00012871 Y45F10B.3 Enriched in amphid sheath cell; arcade cell; pharyngeal-intestinal valve cell; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including manganese chloride; multi-walled carbon nanotube; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00012872 Y45F10B.8 Predicted to enable metal ion binding activity. WB:WBGene00012873 Y45F10B.9 Predicted to enable metal ion binding activity. WB:WBGene00012874 Y45F10B.12 Is affected by several genes including sir-2.1; pmk-1; and clk-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00012875 Y45F10B.13 Predicted to be located in membrane. WB:WBGene00012876 Y45F10B.15 Is affected by several genes including pgl-1; aak-2; and glh-1 based on tiling array and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00012877 Y45F10C.1 Enriched in AFD; AVM; MSpaaaaa; sensory neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00012878 Y45F10C.2 Predicted to be located in extracellular region. Expressed in uterine epithelial cell. WB:WBGene00012879 fbxa-215 Enriched in several structures, including carbon dioxide sensory neurons; germ line; germline precursor cell; head mesodermal cell; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including manganese chloride; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00012880 Y45F10C.4 Predicted to be located in extracellular region. WB:WBGene00012881 Y45F10C.5 No description available WB:WBGene00012882 Y45F10D.1 No description available WB:WBGene00012883 Y45F10D.2 Enriched in mc1DL; mc1DR; mc1V; pm1; and pm2 based on single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including nicotinic acid; rotenone; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00012885 iscu-1 Predicted to enable 2 iron, 2 sulfur cluster binding activity and ferrous iron binding activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to be located in mitochondrial matrix. Expressed in body wall musculature and hypodermis. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma and pre-eclampsia. Is an ortholog of human ISCU (iron-sulfur cluster assembly enzyme). WB:WBGene00012886 Y45F10D.6 Enriched in hypodermis and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-three chemicals including tryptophan; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00012887 Y45F10D.7 Predicted to be involved in rRNA processing. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Human ortholog(s) of this gene implicated in primary open angle glaucoma. Is an ortholog of human WDR36 (WD repeat domain 36). WB:WBGene00012888 sas-6 Enables identical protein binding activity and protein domain specific binding activity. Involved in centriole replication; protein localization; and regulation of cell cycle. Located in centriole and cytoplasm. WB:WBGene00012889 icap-1 Predicted to be involved in integrin-mediated signaling pathway. Is an ortholog of human ITGB1BP1 (integrin subunit beta 1 binding protein 1). WB:WBGene00012890 lact-9 Predicted to enable peptidase activity. Predicted to be involved in proteolysis and regulation of lipid metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human LACTB (lactamase beta). WB:WBGene00012891 sorb-1 Involved in maintenance of mitochondrion location and sarcomere organization. Located in dense body; focal adhesion; and plasma membrane. Expressed in body wall musculature; non-striated muscle; and uterus. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Is an ortholog of human SORBS1 (sorbin and SH3 domain containing 1) and SORBS2 (sorbin and SH3 domain containing 2). WB:WBGene00012892 Y45F10D.14 Predicted to be located in membrane. WB:WBGene00012893 Y45F10D.15 Predicted to be located in membrane. WB:WBGene00012894 tbc-17 Predicted to enable GTPase activator activity. Is an ortholog of human USP6NL (USP6 N-terminal like). WB:WBGene00012895 cox-10 Predicted to enable protoheme IX farnesyltransferase activity. Predicted to be involved in heme A biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX10 (cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10). WB:WBGene00012896 snrp-200 Predicted to enable RNA helicase activity. Predicted to be involved in spliceosome conformational change to release U4 (or U4atac) and U1 (or U11). Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Expressed in excretory cell; gonad; head ganglion; intestine; and pharynx. Used to study retinitis pigmentosa 33. Human ortholog(s) of this gene implicated in retinitis pigmentosa 33. Is an ortholog of human SNRNP200 (small nuclear ribonucleoprotein U5 subunit 200). WB:WBGene00012897 pisy-1 Predicted to enable CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity. Predicted to be involved in phosphatidylinositol biosynthetic process. Predicted to be located in Golgi apparatus. Is an ortholog of human CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase). WB:WBGene00012898 Y46G5A.6 Enriched in sensory neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including aldicarb; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00012899 Y46G5A.7 Enriched in several structures, including germ line; head mesodermal cell; male distal tip cell; pharynx; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; bisphenol S; and Linolenic Acids based on RNA-seq and microarray studies. WB:WBGene00012900 Y46G5A.8 Predicted to be located in membrane. WB:WBGene00012901 cnp-2 Expressed in intestine. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012903 vps-2 Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Located in cytoplasm. Expressed in tail. Is an ortholog of human CHMP2A (charged multivesicular body protein 2A). WB:WBGene00012904 tiar-2 Predicted to enable mRNA binding activity. Involved in several processes, including determination of adult lifespan; hyperosmotic response; and nematode larval development. Located in cytoplasmic stress granule and nucleus. Expressed in several structures, including mechanosensory neurons. Is an ortholog of human TIA1 (TIA1 cytotoxic granule associated RNA binding protein) and TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1). WB:WBGene00012905 Y46G5A.14 Enriched in neurons; retrovesicular ganglion; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; antimycin; and Ag nanoparticles based on microarray and RNA-seq studies. WB:WBGene00012906 Y46G5A.15 Enriched in several structures, including MSpppaaa; head mesodermal cell; muscle cell; serotonergic neurons; and somatic gonad precursor based on RNA-seq; tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by six chemicals including Cry5B; silicon dioxide nanoparticle; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00012907 cpt-1 Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in carnitine metabolic process and fatty acid metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in carnitine palmitoyltransferase I deficiency; hereditary spastic paraplegia 73; and lymphangioleiomyomatosis. Is an ortholog of human CPT1A (carnitine palmitoyltransferase 1A) and CPT1C (carnitine palmitoyltransferase 1C). WB:WBGene00012908 Y46G5A.18 Predicted to enable nucleic acid binding activity. Is an ortholog of human R3HDM4 (R3H domain containing 4). WB:WBGene00012909 spds-1 Predicted to enable spermidine synthase activity. Predicted to be involved in spermidine biosynthetic process. Predicted to be located in cytosol. Is an ortholog of human SRM (spermidine synthase). WB:WBGene00012910 Y46G5A.20 Enriched in intestine; muscle cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including hydrogen sulfide; 1-methylnicotinamide; and stavudine based on microarray and RNA-seq studies. WB:WBGene00012911 acl-7 Predicted to enable glycerol-3-phosphate O-acyltransferase activity and glycerone-phosphate O-acyltransferase activity. Predicted to be involved in cellular lipid metabolic process. Predicted to be located in mitochondrial membrane and peroxisomal membrane. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata type 2. Is an ortholog of human GNPAT (glyceronephosphate O-acyltransferase). WB:WBGene00012912 Y46G5A.22 Predicted to be located in membrane. WB:WBGene00012913 Y46G5A.23 Is affected by several genes including eat-2; isp-1; and csr-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00012914 bcmo-1 Predicted to enable beta-carotene 15,15'-dioxygenase activity and carotenoid dioxygenase activity. Predicted to be involved in carotene catabolic process and retinal metabolic process. Expressed in intestine. Is an ortholog of human BCO1 (beta-carotene oxygenase 1). WB:WBGene00012915 lgc-35 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in head mesodermal cell; neurons; non-striated muscle; and in male. WB:WBGene00012916 Y46G5A.28 Predicted to be located in cytoplasm and nucleus. WB:WBGene00012917 Y46G5A.29 Predicted to enable calcium ion binding activity. WB:WBGene00012918 Y46G5A.32 No description available WB:WBGene00012919 Y46G5A.34 Enriched in several structures, including I5 neuron; cholinergic neurons; rectal epithelial cell; tail hypodermis; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; manganese chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00012920 alkb-7 Predicted to enable dioxygenase activity. Predicted to be involved in fatty acid metabolic process. Predicted to be located in mitochondrial matrix. Is an ortholog of human ALKBH7 (alkB homolog 7). WB:WBGene00012921 Y46G5A.36 Enriched in AFD and ASEL based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercury hydroxide; manganese chloride; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00012922 Y47D3A.1 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. WB:WBGene00012923 fbxa-128 Expressed in pharyngeal-intestinal valve. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00012924 Y47D3A.5 Enriched in I5 neuron; cholinergic neurons; head mesodermal cell; retrovesicular ganglion; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including rrf-3; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00012925 wht-8 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including gout; hematologic cancer (multiple); and toxic encephalopathy. Is an ortholog of human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)). WB:WBGene00012926 Y47D3A.13 Enriched in SIB; germ line; hypodermis; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00012927 Y47D3A.14 Predicted to enable catalytic activity. Predicted to contribute to tRNA-specific adenosine-34 deaminase activity. Predicted to be located in cytoplasm and nucleus. Expressed in pharyngeal gland cell and pm7. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies. Is an ortholog of human ADAT3 (adenosine deaminase tRNA specific 3). WB:WBGene00012928 aakb-2 Predicted to enable protein kinase binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleotide-activated protein kinase complex. Is an ortholog of human PRKAB1 (protein kinase AMP-activated non-catalytic subunit beta 1) and PRKAB2 (protein kinase AMP-activated non-catalytic subunit beta 2). WB:WBGene00012929 rsks-1 Predicted to enable protein serine/threonine kinase activity. Involved in determination of adult lifespan; nematode larval development; and positive regulation of metabolic process. Predicted to be located in cytoplasm and nucleoplasm. Expressed in several structures, including Eala; Ealaa; Ealp; Earaa; and Earp. Is an ortholog of human RPS6KB2 (ribosomal protein S6 kinase B2). WB:WBGene00012930 obr-1 Predicted to enable sterol binding activity and sterol transporter activity. Predicted to be involved in sterol transport. Predicted to be located in cytosol; perinuclear endoplasmic reticulum; and plasma membrane. Human ortholog(s) of this gene implicated in cholangiocarcinoma and colorectal cancer. Is an ortholog of human OSBP (oxysterol binding protein) and OSBP2 (oxysterol binding protein 2). WB:WBGene00012931 Y47D3A.20 Enriched in several structures, including ABarppaapp; ABarpppapp; germ line; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and aak-2 based on RNA-seq; tiling array; and microarray studies. Is affected by eight chemicals including hydrogen sulfide; rotenone; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00012932 Y47D3A.21 Predicted to enable mRNA binding activity. Predicted to be involved in formation of translation preinitiation complex and translation reinitiation. Is an ortholog of human DENR (density regulated re-initiation and release factor). WB:WBGene00012933 mib-1 Predicted to enable ubiquitin protein ligase activity. Expressed in vulva. Human ortholog(s) of this gene implicated in left ventricular noncompaction. Is an ortholog of human MIB1 (MIB E3 ubiquitin protein ligase 1) and MIB2 (MIB E3 ubiquitin protein ligase 2). WB:WBGene00012934 gly-9 Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in Golgi apparatus. WB:WBGene00012935 mcm-10 Predicted to enable DNA replication origin binding activity and single-stranded DNA binding activity. Predicted to be involved in DNA replication initiation. Predicted to be located in nuclear replication fork. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human MCM10 (minichromosome maintenance 10 replication initiation factor). WB:WBGene00012936 pola-1 Predicted to enable DNA binding activity; DNA-directed DNA polymerase activity; and chromatin binding activity. Predicted to be involved in lagging strand elongation; leading strand elongation; and mitotic DNA replication initiation. Predicted to be located in nucleus. Predicted to be part of alpha DNA polymerase:primase complex. Human ortholog(s) of this gene implicated in Van Esch-O'Driscoll syndrome and X-linked reticulate pigmentary disorder. Is an ortholog of human POLA1 (DNA polymerase alpha 1, catalytic subunit). WB:WBGene00012937 Y47D3A.31 Enriched in intestine based on microarray studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including Ethanol; tryptophan; and methylmercury hydroxide based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily. WB:WBGene00012938 Y47D3A.32 Predicted to be located in membrane. WB:WBGene00012939 subs-4 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00012940 Y47D3B.3 Enriched in hypodermis and rectal epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and dpy-7 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like. WB:WBGene00012941 Y47D3B.4 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00012942 idpc-1 Enriched in anterior hypodermis; arcade cell; cholinergic neurons; pharyngeal muscle cell; and pharyngeal-intestinal valve based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-eight chemicals including methylmercury hydroxide; 1-methylnicotinamide; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: EB domain and EB module. WB:WBGene00012943 bed-2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including endocytosis; positive regulation of canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. WB:WBGene00012945 Y47H9A.1 Predicted to be involved in glycoprotein catabolic process. Predicted to be located in cytoplasm. WB:WBGene00012946 Y47H9B.2 Enriched in NSM; SIB; body wall muscle cell; touch receptor neurons; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Nematode trypsin-6-like family and Chymotrypsin family Peptidase-S1. WB:WBGene00012947 Y47H9C.1 Enriched in OLL; PVD; head mesodermal cell; intestine; and pharyngeal muscle cell based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty-one chemicals including Heme; hydrogen sulfide; and Nitric Oxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00012948 dhhc-2 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Raymond type. Is an ortholog of human ZDHHC18 (zinc finger DHHC-type palmitoyltransferase 18) and ZDHHC9 (zinc finger DHHC-type palmitoyltransferase 9). WB:WBGene00012949 Y47H9C.3 No description available WB:WBGene00012950 eif-2Bbeta Predicted to enable translation initiation factor activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter 2. Is an ortholog of human EIF2B2 (eukaryotic translation initiation factor 2B subunit beta). WB:WBGene00012951 Y47H9C.8 Predicted to be located in endoplasmic reticulum. WB:WBGene00012952 Y47H9C.9 Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array and RNA-seq studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1280) and Protein of unknown function DUF1280. WB:WBGene00012953 fbxa-216 Enriched in OLL; PLM; PVD; and somatic gonad precursor based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; Alovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00012954 fbxa-217 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00012955 Y47H9C.12 Is affected by several genes including daf-12; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain and HTH domain in Mos1 transposase. WB:WBGene00012956 Y47H9C.14 Is affected by several genes including daf-12; eat-2; and smg-2 based on tiling array and RNA-seq studies. Is affected by ten chemicals including rotenone; multi-walled carbon nanotube; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00012958 Y47H10A.2 Enriched in germ line; hypodermis; muscle cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including stavudine; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00012959 Y47H10A.3 Predicted to enable mRNA 5'-diphosphatase activity. Predicted to be involved in NAD-cap decapping; nuclear-transcribed mRNA catabolic process; and nucleic acid phosphodiester bond hydrolysis. Predicted to be located in cytosol and nucleus. WB:WBGene00012960 Y47H10A.4 Predicted to enable mRNA 5'-diphosphatase activity. Predicted to be involved in NAD-cap decapping; nuclear-transcribed mRNA catabolic process; and nucleic acid phosphodiester bond hydrolysis. Predicted to be located in cytosol and nucleus. WB:WBGene00012961 Y47H10A.5 Predicted to enable mRNA 5'-diphosphatase activity. Predicted to be involved in NAD-cap decapping; nuclear-transcribed mRNA catabolic process; and nucleic acid phosphodiester bond hydrolysis. Predicted to be located in cytosol and nucleus. Expressed in intestine. WB:WBGene00012962 dmsr-5 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00012964 Y48A6B.3 Predicted to enable box H/ACA snoRNA binding activity. Predicted to be involved in maturation of LSU-rRNA; rRNA pseudouridine synthesis; and snRNA pseudouridine synthesis. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex and cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 2. Is an ortholog of human NHP2 (NHP2 ribonucleoprotein). WB:WBGene00012965 fipr-17 Expressed in vas deferens. Is predicted to encode a protein with the following domain: Fungus-induced protein. WB:WBGene00012966 exos-1 Predicted to be involved in RNA processing. Located in cytoplasm and nucleus. Expressed in head. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1F. Is an ortholog of human EXOSC1 (exosome component 1). WB:WBGene00012967 kvs-4 Predicted to enable delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in axon; plasma membrane; and somatodendritic compartment. Predicted to be part of voltage-gated potassium channel complex. Expressed in AVA and nervous system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26. Is an ortholog of human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1) and KCNS2 (potassium voltage-gated channel modifier subfamily S member 2). WB:WBGene00012968 Y48A6B.7 Predicted to enable guanosine deaminase activity. Predicted to be involved in purine nucleoside catabolic process. WB:WBGene00012969 Y48A6B.8 Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00012970 Y48A6B.9 Predicted to enable trans-2-enoyl-CoA reductase (NADPH) activity. Predicted to be involved in fatty acid metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in dystonia. Is an ortholog of human MECR (mitochondrial trans-2-enoyl-CoA reductase). WB:WBGene00012972 rsa-2 Enables beta-catenin binding activity and protein-macromolecule adaptor activity. Involved in embryonic digestive tract development; mitotic spindle organization; and protein localization to organelle. Located in centrosome. WB:WBGene00012973 spat-2 Enriched in germ line; germline precursor cell; head mesodermal cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by sixteen chemicals including rotenone; Cry5B; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00012974 Y48A6C.1 Enriched in Z1.p; Z4.a; male distal tip cell; and mechanosensory neurons based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; Zidovudine; and metformin based on RNA-seq studies. WB:WBGene00012975 Y48A6C.2 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on RNA-seq and microarray studies. Is affected by Sirolimus and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00012976 sup-35 Predicted to enable microtubule binding activity. Located in cytoplasm and nucleus. Expressed in head muscle; intestine; pharyngeal cell; and pharynx. WB:WBGene00012977 Y48A6C.4 Predicted to be located in nucleus. Predicted to be part of MLL1 complex. Is an ortholog of human TEX10 (testis expressed 10). WB:WBGene00012978 Y48B6A.1 Predicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of PeBoW complex and preribosome, large subunit precursor. Is an ortholog of human BOP1 (BOP1 ribosomal biogenesis factor). WB:WBGene00012979 Y48B6A.5 Predicted to be located in cytoskeleton. WB:WBGene00012980 efhd-1 Predicted to enable calcium ion binding activity. Is an ortholog of human EFHD1 (EF-hand domain family member D1). WB:WBGene00012981 Y48B6A.10 Predicted to enable histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. WB:WBGene00012982 jmjd-2 Enables histone H3K36me/H3K36me2 demethylase activity and histone H3K9me2/H3K9me3 demethylase activity. Predicted to be involved in chromatin remodeling and negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed in pharynx. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); nervous system cancer (multiple); and urinary system cancer (multiple). Is an ortholog of human KDM4C (lysine demethylase 4C). WB:WBGene00012983 men-1 Predicted to enable malate dehydrogenase (decarboxylating) (NADP+) activity. Predicted to be involved in malate metabolic process and pyruvate metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human ME1 (malic enzyme 1) and ME3 (malic enzyme 3). WB:WBGene00012984 Y48B6A.13 Predicted to enable diphosphomevalonate decarboxylase activity. Predicted to be involved in isopentenyl diphosphate biosynthetic process, mevalonate pathway. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in porokeratosis. Is an ortholog of human MVD (mevalonate diphosphate decarboxylase). WB:WBGene00012985 Y48C3A.1 Expressed in head and tail. WB:WBGene00012986 Y48C3A.2 No description available WB:WBGene00012987 Y48C3A.3 Predicted to be located in cytoplasm. Is an ortholog of human FAXC (failed axon connections homolog, metaxin like GST domain containing). WB:WBGene00012988 ztf-22 Expressed in dorsal nerve cord; head muscle; head neurons; intestine; and ventral nerve cord. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00012989 Y48C3A.5 Predicted to be located in membrane. WB:WBGene00012990 sam-10 Involved in negative regulation of gene expression; nervous system development; and regulation of protein localization to synapse. Located in nucleus. Expressed in ganglia; touch receptor neurons; and vulva. Is an ortholog of human SSBP3 (single stranded DNA binding protein 3). WB:WBGene00012992 mrpl-20 Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal large subunit assembly. Predicted to be located in mitochondrial ribosome. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human MRPL20 (mitochondrial ribosomal protein L20). WB:WBGene00012993 dmsr-3 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00012994 Y48C3A.12 Predicted to be involved in regulation of transcription by RNA polymerase II. WB:WBGene00012995 Y48C3A.14 Predicted to enable DNA topoisomerase activity. Predicted to be involved in DNA topological change. Predicted to be located in nucleus. Expressed in head. Is an ortholog of human TOP3B (DNA topoisomerase III beta). WB:WBGene00012996 pinn-4 Predicted to enable DNA binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in rRNA processing. Located in plasma membrane. Expressed in head; intestinal cell; and tail. Is an ortholog of human PIN4 (peptidylprolyl cis/trans isomerase, NIMA-interacting 4). WB:WBGene00012997 Y48C3A.18 Predicted to enable nucleotidyltransferase activity and tRNA binding activity. Predicted to be involved in regulation of translational fidelity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome. Is an ortholog of human YRDC (yrdC N6-threonylcarbamoyltransferase domain containing). WB:WBGene00012998 Y48C3A.20 Predicted to enable pseudouridine synthase activity. Predicted to be involved in tRNA pseudouridine synthesis. Is an ortholog of human PUS10 (pseudouridine synthase 10). WB:WBGene00012999 rpoa-1 Predicted to enable DNA binding activity and DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase I activity. Predicted to be involved in transcription by RNA polymerase I. Predicted to be located in nuclear lumen. Predicted to be part of RNA polymerase I complex. Human ortholog(s) of this gene implicated in acrofacial dysostosis Cincinnati type. Is an ortholog of human POLR1A (RNA polymerase I subunit A). WB:WBGene00013000 ddl-2 Predicted to enable alpha-tubulin binding activity and gamma-tubulin binding activity. Involved in cytoplasmic sequestering of protein and determination of adult lifespan. Predicted to be located in early endosome and recycling endosome. Predicted to be part of WASH complex. Expressed in neurons. Is an ortholog of human WASH2P (WASP family homolog 2, pseudogene) and WASHC1 (WASH complex subunit 1). WB:WBGene00013001 noa-1 Predicted to enable GTP binding activity. Predicted to be extrinsic component of mitochondrial inner membrane. Is an ortholog of human NOA1 (nitric oxide associated 1). WB:WBGene00013002 Y48E1B.3 Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly. Predicted to be located in fibrillar center. WB:WBGene00013004 mrpl-37 Predicted to be located in mitochondrion. Is an ortholog of human MRPL37 (mitochondrial ribosomal protein L37). WB:WBGene00013006 lin-38 Involved in negative regulation of vulval development. WB:WBGene00013007 Y48E1B.8 Predicted to enable transferase activity. Predicted to be located in membrane. WB:WBGene00013008 clec-146 Enriched in AFD; dopaminergic neurons; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including rotenone; stavudine; and Sodium Chloride based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00013009 fbxc-23 Enriched in several structures, including ABaraapapp; ABaraapppp; AVE; B cell; and intestine based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; hsf-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Rifampin; allantoin; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00013010 C12C8.t4 No description available WB:WBGene00013011 snx-14 Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in autophagosome maturation. Predicted to be located in late endosome. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 20. Is an ortholog of human SNX14 (sorting nexin 14). WB:WBGene00013013 clec-145 Enriched in coelomocyte based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00013014 Y48E1C.1 Predicted to enable chromatin binding activity. Predicted to be involved in replication fork processing and resolution of meiotic recombination intermediates. Predicted to be part of FANCM-MHF complex. Is an ortholog of human CENPS (centromere protein S) and CENPS-CORT (CENPS-CORT readthrough). WB:WBGene00013015 Y48E1C.2 Predicted to enable carnosine N-methyltransferase activity. WB:WBGene00013017 Y48E1C.4 Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-7 based on proteomic; RNA-seq; and microarray studies. Is affected by eight chemicals including rotenone; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00013018 Y48G10A.1 Predicted to enable S-formylglutathione hydrolase activity. Predicted to be involved in formaldehyde catabolic process. Predicted to be located in cytosol. Is an ortholog of human ESD (esterase D). WB:WBGene00013019 Y48G10A.2 Predicted to enable transferase activity. WB:WBGene00013020 Y48G10A.3 Predicted to be involved in signal transduction. Located in striated muscle dense body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4D and glioblastoma. Is an ortholog of human NDRG1 (N-myc downstream regulated 1); NDRG2 (NDRG family member 2); and NDRG3 (NDRG family member 3). WB:WBGene00013021 ints-8 Predicted to be involved in snRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of integrator complex. Is an ortholog of human INTS8 (integrator complex subunit 8). WB:WBGene00013022 Y48G10A.5 No description available WB:WBGene00013023 Y48G10A.6 Enriched in AUA and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00013024 cept-2 Predicted to enable diacylglycerol cholinephosphotransferase activity and ethanolaminephosphotransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be located in Golgi apparatus and endoplasmic reticulum membrane. Is an ortholog of human CHPT1 (choline phosphotransferase 1). WB:WBGene00013025 vha-13 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in lysosomal lumen acidification. Predicted to be part of proton-transporting V-type ATPase, V1 domain. Expressed in head. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IID and developmental and epileptic encephalopathy 93. Is an ortholog of human ATP6V1A (ATPase H+ transporting V1 subunit A). WB:WBGene00013026 Y49A3A.3 Predicted to enable tRNA methyltransferase activity. Predicted to be involved in tRNA methylation. Is an ortholog of human TRMT13 (tRNA methyltransferase 13 homolog). WB:WBGene00013027 Y49A3A.4 Enriched in arcade cell; corpus; muscle cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including bisphenol S; Sodium Chloride; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00013028 efhc-1 Predicted to enable alpha-tubulin binding activity. Predicted to be involved in cilium-dependent cell motility; mitotic cytokinesis; and mitotic spindle organization. Predicted to be located in axoneme and mitotic spindle. Expressed in ciliated neurons and ray. Human ortholog(s) of this gene implicated in juvenile absence epilepsy 1 and juvenile myoclonic epilepsy. Is an ortholog of human EFHC1 (EF-hand domain containing 1). WB:WBGene00013029 glrx-5 Predicted to enable iron-sulfur cluster binding activity and metal ion binding activity. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in autosomal recessive pyridoxine-refractory sideroblastic anemia 3. Is an ortholog of human GLRX5 (glutaredoxin 5). WB:WBGene00013030 Y49E10.4 Predicted to enable protein-disulfide reductase activity. Predicted to be involved in response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum lumen. Is an ortholog of human PDIA6 (protein disulfide isomerase family A member 6). WB:WBGene00013031 Y49E10.7 Is affected by several genes including clk-1; pgl-1; and unc-30 based on microarray and RNA-seq studies. Is affected by six chemicals including D-glucopyranose; multi-walled carbon nanotube; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00013032 wht-9 Is affected by several genes including daf-2; glp-1; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by eight chemicals including methylmercuric chloride; multi-walled carbon nanotube; and metformin based on microarray and RNA-seq studies. WB:WBGene00013033 Y49E10.10 Predicted to be located in membrane. WB:WBGene00013034 tat-1 Enables ATPase-coupled intramembrane lipid transporter activity. Involved in several processes, including lysosome organization; phospholipid translocation; and regulation of phagocytosis, engulfment. Located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and endosome. Expressed in several structures, including intestine. Human ortholog(s) of this gene implicated in cerebellar ataxia, mental retardation and dysequlibrium syndrome. Is an ortholog of human ATP8A2 (ATPase phospholipid transporting 8A2). WB:WBGene00013035 Y49E10.16 Predicted to be involved in lipid metabolic process. WB:WBGene00013036 fbxa-218 Enriched in ABplpppaaa; ABprpppaaa; body wall musculature; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; npr-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00013037 Y49E10.18 Predicted to be involved in lipid metabolic process. WB:WBGene00013038 ani-1 Enables actin filament binding activity; microtubule binding activity; and small GTPase binding activity. Involved in several processes, including first cell cycle pseudocleavage; nematode male tail tip morphogenesis; and organelle organization. Located in several cellular components, including cleavage furrow; growth cone; and midbody. Expressed in several structures, including QL.a; QL.pa; germ line; neuroblasts; and neurons. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Is an ortholog of human ANLN (anillin, actin binding protein). WB:WBGene00013039 scav-3 Predicted to enable scavenger receptor activity. Predicted to be involved in endocytosis. Predicted to be located in cytoplasm. Expressed in gonadal sheath cell; hypodermis; tail; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); myeloproliferative neoplasm (multiple); and myositis (multiple). Is an ortholog of human SCARB1 (scavenger receptor class B member 1). WB:WBGene00013040 Y49E10.21 Enriched in several structures, including ABaraapapp; I5 neuron; intestine; mechanosensory neurons; and rectal muscle based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including sma-2; sma-4; and smg-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00013041 pstk-1 Predicted to enable kinase activity and tRNA binding activity. Predicted to be involved in phosphorylation. Is an ortholog of human PSTK (phosphoseryl-tRNA kinase). WB:WBGene00013042 cccp-1 Enables small GTPase binding activity. Involved in dense core granule maturation and regulation of locomotion involved in locomotory behavior. Located in axon; neuronal cell body; and perinuclear region of cytoplasm. Expressed in intestine and spermatheca. Is an ortholog of human CCDC186 (coiled-coil domain containing 186). WB:WBGene00013043 arrd-16 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC5 (arrestin domain containing 5). WB:WBGene00013044 Y49E10.25 Predicted to be involved in lipid metabolic process. WB:WBGene00013045 Y49E10.27 Predicted to enable metal ion binding activity. WB:WBGene00013046 Y50E8A.1 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00013047 Y50E8A.2 Predicted to be located in cytoskeleton. WB:WBGene00013048 Y50E8A.5 Enriched in several structures, including ABalaaaarl; ABalaaaarr; head neurons; pharynx; and rectal epithelial cell based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; multi-walled carbon nanotube; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00013049 Y50E8A.6 Predicted to enable sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity. Predicted to be involved in glycerol-3-phosphate metabolic process. Predicted to be located in mitochondrion. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is an ortholog of human GPD2 (glycerol-3-phosphate dehydrogenase 2). WB:WBGene00013050 lipl-8 Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be involved in lipid catabolic process. WB:WBGene00013051 Y50E8A.8 Enriched in male-specific anatomical entity based on microarray studies. Is affected by daf-16; dpy-7; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013052 scrm-7 Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be located in plasma membrane. WB:WBGene00013053 Y50E8A.10 Predicted to be located in membrane. WB:WBGene00013054 Y50E8A.11 Predicted to be involved in integrin-mediated signaling pathway. Predicted to be located in membrane. WB:WBGene00013055 Y50E8A.12 Enriched in several structures, including ADE sheath cell; AVK; germline precursor cell; head mesodermal cell; and pm8 based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: THAP domain and THAP-type zinc finger. WB:WBGene00013056 Y50E8A.14 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray studies. Is affected by four chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00013058 clec-247 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-2; rrf-3; and lin-4 based on microarray and RNA-seq studies. Is affected by four chemicals including glycine; Cry5B; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00013059 Y51A2A.3 Is affected by several genes including daf-2; rrf-3; and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00013060 Y51A2A.4 Enriched in dopaminergic neurons; excretory gland cell; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by fluoranthene and triclosan based on microarray studies. WB:WBGene00013061 Y51A2A.5 Is affected by several genes including eat-2; pgl-1; and glh-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013062 Y51A2A.6 Is affected by rsr-2; hda-1; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domain: C-type lectin fold. WB:WBGene00013063 clec-249 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00013064 clec-248 Is affected by several genes including lin-4; lin-14; and cnd-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00013066 Y51A2B.2 Predicted to be located in membrane. WB:WBGene00013067 nhr-288 Predicted to be located in nucleus. WB:WBGene00013068 Y51A2B.4 Predicted to be involved in lipid metabolic process. WB:WBGene00013069 Y51A2B.5 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CAP superfamily. WB:WBGene00013070 Y51A2B.6 Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq; tiling array; and microarray studies. Is affected by nine chemicals including methylmercuric chloride; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Domain of unknown function WSN. WB:WBGene00013071 Y51A2B.8 Enriched in AFD; ASEL; ASER; PLM; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and aak-2 based on tiling array; microarray; and RNA-seq studies. Is affected by Mercuric Chloride based on microarray studies. WB:WBGene00013072 Y51A2D.1 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSO (cathepsin O). WB:WBGene00013073 hmit-1.1 Predicted to enable myo-inositol:proton symporter activity. Predicted to be involved in myo-inositol transport and transmembrane transport. Located in apical plasma membrane. Expressed in intestinal cell. Is an ortholog of human SLC2A13 (solute carrier family 2 member 13). WB:WBGene00013074 hmit-1.2 Predicted to enable myo-inositol:proton symporter activity. Predicted to be involved in myo-inositol transport and transmembrane transport. Located in apical plasma membrane and basal plasma membrane. Expressed in amphid sheath cell; excretory canal; and phasmid sheath cell. Is an ortholog of human SLC2A13 (solute carrier family 2 member 13). WB:WBGene00013075 ints-5 Predicted to be involved in snRNA 3'-end processing. Predicted to be part of integrator complex. Is an ortholog of human INTS5 (integrator complex subunit 5). WB:WBGene00013076 Y51A2D.8 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSW (cathepsin W). WB:WBGene00013077 ttr-24 Predicted to be located in cell surface and extracellular region. WB:WBGene00013078 ttr-25 Predicted to be located in cell surface and extracellular region. WB:WBGene00013079 ttr-26 Predicted to be located in cell surface and extracellular region. WB:WBGene00013080 Y51A2D.13 Predicted to enable catalytic activity. Predicted to be located in membrane. Is an ortholog of human PLD5 (phospholipase D family member 5). WB:WBGene00013081 txt-14 Enriched in head mesodermal cell; intestine; mechanosensory neurons; and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on RNA-seq and microarray studies. Is affected by seventeen chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00013082 grdn-1 Predicted to enable dynein light intermediate chain binding activity and microtubule binding activity. Involved in several processes, including plasma membrane bounded cell projection organization; positive regulation of cell projection organization; and positive regulation of dendrite extension. Located in centriole and ciliary basal body. Expressed in AQR; PQR; and sensory neurons. Human ortholog(s) of this gene implicated in hydrocephalus and spinocerebellar ataxia type 40. Is an ortholog of human CCDC88A (coiled-coil domain containing 88A) and CCDC88C (coiled-coil domain containing 88C). WB:WBGene00013083 Y51A2D.18 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00013085 mpz-6 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterized protein T15H9.4-like and PDZ superfamily. WB:WBGene00013086 arrd-2 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. WB:WBGene00013087 Y51B9A.5 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00013088 Y51B9A.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00013089 Y51B9A.7 Predicted to be located in membrane. WB:WBGene00013090 Y51B9A.8 Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including nanoparticle; Cisplatin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: CC domain; ShK domain-like; and ShKT domain. WB:WBGene00013091 Y51B9A.9 Predicted to enable MAP kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and nucleus. WB:WBGene00013093 cup-14 Involved in lysosome organization. Predicted to be located in endosome. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 6. Is an ortholog of human PLEKHM1 (pleckstrin homology and RUN domain containing M1). WB:WBGene00013094 ndub-8 Predicted to be located in mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and nuclear type mitochondrial complex I deficiency 32. Is an ortholog of human NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8). WB:WBGene00013095 ing-3 Predicted to enable methylated histone binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Expressed in several structures, including hypodermis; intestine; pharynx; spermatheca; and vulva. Used to study cancer. Human ortholog(s) of this gene implicated in head and neck squamous cell carcinoma. Is an ortholog of human ING3 (inhibitor of growth family member 3). WB:WBGene00013096 mcd-1 Predicted to enable metal ion binding activity. Involved in nematode larval development; positive regulation of growth rate; and programmed cell death. WB:WBGene00013098 Y51H4A.1 Enriched in several structures, including ABalaapppa; ABalapaaaa; ABalapaapa; head mesodermal cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; sek-1; and tph-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including 1-methylnicotinamide; metformin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00013100 zip-7 Enables identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00013101 Y51H4A.5 Predicted to be involved in lipid metabolic process. WB:WBGene00013102 Y51H4A.6 Is affected by rsr-2; daf-2; and pmt-2 based on tiling array and microarray studies. Is affected by paraquat based on microarray studies. WB:WBGene00013103 uroc-1 Predicted to enable urocanate hydratase activity. Predicted to be involved in histidine catabolic process. Human ortholog(s) of this gene implicated in urocanase deficiency. Is an ortholog of human UROC1 (urocanate hydratase 1). WB:WBGene00013104 Y51H4A.8 Enriched in several structures, including AVH; arcade cell; head mesodermal cell; pharyngeal-intestinal valve cell; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Alovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00013105 fip-7 Enriched in male based on RNA-seq studies. Is affected by several genes including clk-1; tph-1; and cat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00013106 set-26 Enables histone H3K9 methyltransferase activity. Predicted to be involved in chromatin remodeling and methylation. Predicted to be located in nucleus. Expressed in several structures, including germ cell; hypodermis; intestine; muscle cell; and somatic cell. WB:WBGene00013107 Y51H4A.13 Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleus. Is an ortholog of human KHNYN (KH and NYN domain containing); N4BP1 (NEDD4 binding protein 1); and NYNRIN (NYN domain and retroviral integrase containing). WB:WBGene00013108 Y51H4A.14 No description available WB:WBGene00013109 Y51H4A.15 Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 14 with mandibulofacial dysostosis. Is an ortholog of human TSR2 (TSR2 ribosome maturation factor). WB:WBGene00013111 sta-1 Enables sequence-specific DNA binding activity. Involved in dauer larval development and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Expressed in coelomocyte; head; somatic nervous system; and tail ganglion. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human STAT5A (signal transducer and activator of transcription 5A) and STAT5B (signal transducer and activator of transcription 5B). WB:WBGene00013112 Y51H4A.18 Is affected by several genes including daf-16; pmk-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by Atrazine and cadmium based on microarray studies. WB:WBGene00013113 Y51H4A.19 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. Is affected by cadmium based on microarray studies. WB:WBGene00013114 Y51H4A.20 Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. WB:WBGene00013116 Y51H4A.22 Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including methylmercuric chloride; Tunicamycin; and metformin based on microarray and RNA-seq studies. WB:WBGene00013117 Y51H4A.23 Is affected by wdr-23 and set-2 based on RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00013118 Y51H4A.24 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and ABarpppapa based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; glp-1; and age-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Rifampin; allantoin; and fluvastatin based on RNA-seq and microarray studies. WB:WBGene00013119 Y51H4A.25 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00013120 fipr-28 Enriched in male based on RNA-seq studies. Is affected by several genes including age-1; rrf-3; and tph-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00013121 spe-38 Involved in sperm entry. Located in cell cortex. Expressed in sperm and spermatid. WB:WBGene00013122 impt-1 Predicted to enable protein sequestering activity. Predicted to be involved in cellular response to amino acid starvation and regulation of cytoplasmic translational initiation in response to stress. Predicted to be located in cytoplasm. Is an ortholog of human IMPACT (impact RWD domain protein). WB:WBGene00013123 Y52B11A.3 Predicted to enable cytochrome-b5 reductase activity, acting on NAD(P)H and metal ion binding activity. WB:WBGene00013124 Y52B11A.4 Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in congestive heart failure and type 2 diabetes mellitus. Is an ortholog of human REM1 (RRAD and GEM like GTPase 1); REM2 (RRAD and GEM like GTPase 2); and RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator). WB:WBGene00013125 clec-92 Enriched in germ line; head mesodermal cell; neurons; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00013126 mltn-2 Predicted to be located in membrane. WB:WBGene00013127 Y52B11A.8 Predicted to enable phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion and phospholipid metabolic process. Predicted to be located in extracellular region. WB:WBGene00013128 dxbp-1 Predicted to enable double-stranded DNA binding activity. Predicted to be involved in DNA damage response and DNA replication. Located in nucleolus. Expressed in several structures, including somatic cell. Is an ortholog of human KIN (Kin17 DNA and RNA binding protein). WB:WBGene00013129 Y52B11A.10 Predicted to enable RNA binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Is an ortholog of human NOM1 (nucleolar protein with MIF4G domain 1). WB:WBGene00013130 Y52B11B.1 Enriched in hypodermis and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including Ethanol; methylmercury hydroxide; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00013131 pigl-1 Predicted to enable N-acetylglucosaminylphosphatidylinositol deacetylase activity. Human ortholog(s) of this gene implicated in CHIME syndrome. Is an ortholog of human PIGL (phosphatidylinositol glycan anchor biosynthesis class L). WB:WBGene00013132 strd-1 Enables protein kinase binding activity and protein serine/threonine kinase activator activity. Involved in several processes, including asymmetric neuroblast division; maintenance of dauer; and positive regulation of peptidyl-threonine phosphorylation. Located in several cellular components, including cell body; cell cortex; and neuron projection. Expressed in excretory canal; nervous system; and pharynx. Is an ortholog of human STRADA (STE20 related adaptor alpha) and STRADB (STE20 related adaptor beta). WB:WBGene00013134 hsf-2 Expressed in head neurons. WB:WBGene00013135 rga-2 Predicted to enable GTPase activator activity. Predicted to be involved in signal transduction. Expressed in rectum; socket cell; uterus; and vulva. Is an ortholog of human ARHGAP20 (Rho GTPase activating protein 20). WB:WBGene00013136 tmem-189 Predicted to enable plasmanylethanolamine desaturase activity. Predicted to be involved in ether lipid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human PEDS1 (plasmanylethanolamine desaturase 1) and PEDS1-UBE2V1 (PEDS1-UBE2V1 readthrough). WB:WBGene00013137 Y53C10A.6 Enriched in several structures, including body wall muscle cell; germ line; hypodermis; rect_D; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including rotenone; Zidovudine; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013138 Y53C10A.10 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; amphid sheath cell; and germ line based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00013139 Y53C12A.3 Predicted to be located in Golgi apparatus. Is an ortholog of human YIPF3 (Yip1 domain family member 3). WB:WBGene00013140 mop-25.2 Predicted to enable protein serine/threonine kinase activator activity. Involved in asymmetric neuroblast division. Predicted to be located in cytoplasm and spindle pole. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and pancreatic cancer. Is an ortholog of human CAB39 (calcium binding protein 39) and CAB39L (calcium binding protein 39 like). WB:WBGene00013141 Y53C12A.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including methylmercuric chloride; Aspirin; and stavudine based on microarray and RNA-seq studies. WB:WBGene00013142 Y53C12A.7 Enriched in hypodermis and in male based on RNA-seq studies. Is affected by several genes including skn-1; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including tryptophan; methylmercuric chloride; and mianserin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Armadillo-type fold; HEAT repeat; and Armadillo-like helical. WB:WBGene00013143 Y53C12B.1 Predicted to enable U3 snoRNA binding activity. Predicted to be involved in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of 90S preribosome. Expressed in tail. Is an ortholog of human TBL3 (transducin beta like 3). WB:WBGene00013144 pno-1 Predicted to enable RNA binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human PNO1 (partner of NOB1 homolog). WB:WBGene00013145 cutl-2 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and anterior hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; methylmercuric chloride; and mianserin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Zona pellucida-like domain and Zona pellucida domain. WB:WBGene00013146 Y53C12B.7 Predicted to be located in membrane. WB:WBGene00013147 eyg-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head and pharynx. WB:WBGene00013148 Y53F4A.2 Enriched in neurons; somatic gonad precursor; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and clk-1 based on RNA-seq; proteomic; and microarray studies. Is affected by thirteen chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00013149 Y53F4B.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00013150 pole-4 Predicted to enable protein heterodimerization activity. Predicted to be involved in DNA-templated DNA replication. Predicted to be located in nucleus. Predicted to be part of epsilon DNA polymerase complex. Is an ortholog of human POLE4 (DNA polymerase epsilon 4, accessory subunit). WB:WBGene00013151 nsun-5 Enables rRNA (cytosine-C5-)-methyltransferase activity. Involved in several processes, including negative regulation of cellular response to heat; negative regulation of locomotion involved in locomotory behavior; and positive regulation of rRNA processing. Predicted to be located in nucleolus. Used to study Williams-Beuren syndrome. Is an ortholog of human NSUN5 (NOP2/Sun RNA methyltransferase 5). WB:WBGene00013152 Y53F4B.5 Enriched in germline precursor cell based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and mex-3 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00013153 Y53F4B.6 Enriched in head mesodermal cell and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; skn-1; and clk-1 based on microarray and RNA-seq studies. Is affected by copper sulfate and Sirolimus based on microarray studies. WB:WBGene00013154 Y53F4B.7 Enriched in ABalaaaarl; ABalaaaarr; XXXL; XXXR; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Sodium Chloride; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00013155 Y53F4B.8 Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Mercuric Chloride; rotenone; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00013156 Y53F4B.9 Predicted to enable DNA binding activity. Predicted to be involved in phosphorylation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in neurilemmoma. Is an ortholog of human ATAD5 (ATPase family AAA domain containing 5). WB:WBGene00013157 Y53F4B.10 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013158 Y53F4B.11 Enriched in sperm and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nineteen chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00013159 Y53F4B.12 Predicted to enable L-lysine transmembrane transporter activity and L-ornithine transmembrane transporter activity. Predicted to be involved in L-arginine import across plasma membrane and L-ornithine transmembrane transport. Predicted to be located in plasma membrane. WB:WBGene00013160 cmtr-1 Predicted to enable mRNA (nucleoside-2'-O-)-methyltransferase activity. Predicted to be involved in 7-methylguanosine mRNA capping and cap1 mRNA methylation. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human CMTR1 (cap methyltransferase 1). WB:WBGene00013161 Y53F4B.14 Predicted to enable unfolded protein binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in membrane and mitochondrion. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human PET100 (PET100 cytochrome c oxidase chaperone). WB:WBGene00013162 Y53F4B.16 Enriched in ABplpappaa; OLQDL; OLQDR; OLQVL; and OLQVR based on single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and nhr-49 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Doxycycline; and dafa#1 based on RNA-seq and microarray studies. WB:WBGene00013163 Y53F4B.17 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-2; clk-1; and csr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013164 Y53F4B.18 Predicted to be located in membrane. Is an ortholog of human FAAH2 (fatty acid amide hydrolase 2). WB:WBGene00013165 Y53F4B.19 Predicted to be located in cytoskeleton. WB:WBGene00013166 Y53F4B.20 Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human LVRN (laeverin). WB:WBGene00013167 Y53F4B.21 Predicted to be involved in endosomal transport and endosome organization. Predicted to be located in endosome. Predicted to be part of WASH complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 43. Is an ortholog of human WASHC4 (WASH complex subunit 4). WB:WBGene00013168 arp-1 Part of dynactin complex. Human ortholog(s) of this gene implicated in Down syndrome and colon cancer. Is an ortholog of human ACTR1A (actin related protein 1A). WB:WBGene00013169 Y53F4B.23 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00013170 Y53F4B.24 Enriched in ABarpaaa and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; elt-2; and clk-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including methylmercuric chloride; manganese chloride; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00013171 Y53F4B.25 Enriched in ADE sheath cell; germline precursor cell; hypodermis; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00013172 Y53F4B.26 Is affected by several genes including pgl-1; dcr-1; and lin-15B based on microarray and RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00013173 Y53F4B.27 Predicted to enable helicase activity. WB:WBGene00013174 Y53F4B.34 No description available WB:WBGene00013175 Y53F4B.36 Enriched in neurons; retrovesicular ganglion; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including D-glucose; antimycin; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00013176 Y53F4B.39 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. Predicted to be located in mitochondrial matrix. Is an ortholog of human LACTB2 (lactamase beta 2). WB:WBGene00013177 rsy-1 Located in nucleus and presynaptic active zone. Expressed in HSNL and neurons. Is an ortholog of human PNISR (PNN interacting serine and arginine rich protein). WB:WBGene00013178 Y53H1A.2 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; germ line; and rect_D based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: Zinc-finger C2H2-type 11; Zinc finger C2H2-type; zinc-finger C2H2-type; Zinc finger C2H2 superfamily; and Phosphorylation site. WB:WBGene00013179 clec-100 Is affected by several genes including pgl-1; mex-1; and glh-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Atrazine based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00013180 cutl-10 Predicted to be located in membrane. Expressed in posterior gonad arm. WB:WBGene00013181 Y53H1B.2 Enriched in several structures, including PLM; anterior hypodermis; body wall musculature; muscle cell; and rectal epithelial cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by twenty chemicals including aldicarb; diallyl trisulfide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00013182 Y53H1B.4 Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including pgl-1; alg-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by Tunicamycin; Alovudine; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00013184 clpr-4 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00013186 Y53H1C.3 Predicted to be located in membrane. WB:WBGene00013187 npr-34 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00013188 smg-9 Enables molecular sequestering activity. Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human SMG9 (SMG9 nonsense mediated mRNA decay factor). WB:WBGene00013189 Y54E2A.4 Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and helicase activity. Predicted to be involved in gene expression and nucleic acid metabolic process. Is an ortholog of human ASCC3 (activating signal cointegrator 1 complex subunit 3). WB:WBGene00013190 Y54E2A.5 Predicted to be located in membrane. WB:WBGene00013192 Y54E2A.7 Predicted to be located in membrane. WB:WBGene00013193 Y54E2A.8 Predicted to enable protein heterodimerization activity. Predicted to be part of transcription factor TFIID complex. WB:WBGene00013194 Y54E2A.9 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00013195 Y54E2A.10 Predicted to be located in membrane. Predicted to be part of acetylcholine-gated channel complex. WB:WBGene00013196 tbc-20 Predicted to enable GTPase activator activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Warburg micro syndrome 4. Is an ortholog of human TBC1D20 (TBC1 domain family member 20). WB:WBGene00013197 ttm-5 Predicted to enable sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 18. Is an ortholog of human DEGS1 (delta 4-desaturase, sphingolipid 1) and DEGS2 (delta 4-desaturase, sphingolipid 2). WB:WBGene00013198 Y54E5A.2 Predicted to be located in membrane. WB:WBGene00013200 Y54E5A.5 Located in sarcoplasmic reticulum. Is an ortholog of human PBDC1 (polysaccharide biosynthesis domain containing 1). WB:WBGene00013201 dus-2 Predicted to enable tRNA dihydrouridine synthase activity. Predicted to be involved in tRNA dihydrouridine synthesis. Predicted to be located in cytoplasm. Is an ortholog of human DUS2 (dihydrouridine synthase 2). WB:WBGene00013202 gid-1 Expressed in germ line and oocyte. Human RANBP9 enables enzyme binding activity. Is predicted to encode a protein with the following domain: CTLH, C-terminal LisH motif. Is an ortholog of human RANBP10 (RAN binding protein 10) and RANBP9 (RAN binding protein 9). WB:WBGene00013203 Y54E5A.8 Predicted to be located in membrane. WB:WBGene00013204 Y54E5B.2 Predicted to enable snoRNA binding activity. Predicted to be part of small-subunit processome. WB:WBGene00013207 zipt-2.3 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Located in gut granule. Expressed in intestinal cell. Is an ortholog of human SLC39A1 (solute carrier family 39 member 1) and SLC39A2 (solute carrier family 39 member 2). WB:WBGene00013208 Y54G9A.5 Enriched in several structures, including ABalpppappp; AFD; RIC; germ line; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including dpy-10; gld-1; and elt-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00013209 bub-3 Predicted to enable ubiquitin binding activity. Involved in embryo development; meiotic spindle assembly checkpoint signaling; and mitotic spindle assembly checkpoint signaling. Located in nucleoplasm. Is an ortholog of human BUB3 (BUB3 mitotic checkpoint protein). WB:WBGene00013210 Y54G9A.7 Predicted to be located in mitochondrion. WB:WBGene00013211 Y54G9A.9 Predicted to be located in membrane. WB:WBGene00013212 Y54G11A.1 Predicted to be located in membrane. WB:WBGene00013213 Y54G11A.2 Predicted to be located in endomembrane system. Is an ortholog of human CCDC25 (coiled-coil domain containing 25). WB:WBGene00013214 Y54G11A.3 Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be located in P granule. Is an ortholog of human DDX53 (DEAD-box helicase 53). WB:WBGene00013215 Y54G11A.4 Enriched in intestine; neurons; and somatic gonad precursor based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Tetratricopeptide-like helical domain superfamily and Tetratricopeptide repeat protein 38. Is an ortholog of human TTC38 (tetratricopeptide repeat domain 38). WB:WBGene00013216 Y54G11A.7 Enriched in several structures, including body wall musculature; coelomocyte; muscle cell; neurons; and somatic nervous system based on Chronogram; microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eighteen chemicals including Heme; rotenone; and Zidovudine based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Tetratricopeptide-like helical domain superfamily and Tetratricopeptide repeat protein 38. Is an ortholog of human TTC38 (tetratricopeptide repeat domain 38). WB:WBGene00013217 ddl-3 Predicted to be involved in mitochondrial respiratory chain complex III assembly. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 2. Is an ortholog of human TTC19 (tetratricopeptide repeat domain 19). WB:WBGene00013218 Y54G11A.9 Predicted to enable 2 iron, 2 sulfur cluster binding activity; 4 iron, 4 sulfur cluster binding activity; and iron ion binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by [4Fe-4S] cluster transfer. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 4. Is an ortholog of human ISCA2 (iron-sulfur cluster assembly 2). WB:WBGene00013219 elof-1 Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Located in nucleolus. Is an ortholog of human ELOF1 (elongation factor 1). WB:WBGene00013220 ctl-3 Predicted to enable catalase activity and heme binding activity. Predicted to be involved in hydrogen peroxide catabolic process and response to hydrogen peroxide. Predicted to be located in mitochondrion and peroxisome. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple). Is an ortholog of human CAT (catalase). WB:WBGene00013221 Y54G11A.14 Predicted to be located in membrane. WB:WBGene00013222 dmsr-6 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00013223 efa-6 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in several processes, including cellular component disassembly; regulation of cellular component organization; and regulation of mitotic centrosome separation. Located in cell cortex; microtubule minus-end; and plasma membrane. Expressed in U.la; U.lp; and linker cell. Is an ortholog of human PSD (pleckstrin and Sec7 domain containing). WB:WBGene00013224 Y55D9A.2 Predicted to enable nucleic acid binding activity. Is an ortholog of human AGGF1 (angiogenic factor with G-patch and FHA domains 1). WB:WBGene00013225 Y56A3A.2 Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein intracellular domain proteolysis; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress; and regulation of response to endoplasmic reticulum stress. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in X-linked recessive disease (multiple). Is an ortholog of human MBTPS2 (membrane bound transcription factor peptidase, site 2). WB:WBGene00013226 faah-5 Predicted to enable amidase activity and fatty acid amide hydrolase activity. Predicted to be involved in fatty acid catabolic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Is an ortholog of human FAAH (fatty acid amide hydrolase). WB:WBGene00013227 Y56A3A.6 Predicted to be located in cytoplasm and nucleus. Expressed in germ line. WB:WBGene00013228 Y56A3A.7 Predicted to enable DNA binding activity. Expressed in excretory system; gonad; hypodermis; intestine; and pharynx. WB:WBGene00013229 Y56A3A.9 No description available WB:WBGene00013230 fbxb-22 Enriched in arcade cell; hypodermis; and pm8 based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; methylmercuric chloride; and Mercuric Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00013231 tsen-2 Predicted to enable tRNA-intron endonuclease activity. Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to be located in nucleus. Predicted to be part of tRNA-intron endonuclease complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2B. Is an ortholog of human TSEN2 (tRNA splicing endonuclease subunit 2). WB:WBGene00013232 faah-4 Predicted to enable amidase activity and fatty acid amide hydrolase activity. Predicted to be involved in fatty acid catabolic process. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Is an ortholog of human FAAH (fatty acid amide hydrolase). WB:WBGene00013233 sdz-33 Expressed in several structures, including Caa; Cap; Cpa; Ea; and Psub4. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00013234 fbxb-24 Enriched in AIZ; CAN; head mesodermal cell; and neuronal sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00013235 Y56A3A.16 Predicted to enable phosphatidylinositol phosphate binding activity. Predicted to be located in intracellular membrane-bounded organelle. Expressed in intestine; neurons; and pharynx. WB:WBGene00013236 znf-593 Predicted to enable metal ion binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in cytoplasm and nucleus. Expressed in head. Is an ortholog of human ZNF593 (zinc finger protein 593). WB:WBGene00013237 ndab-1 Predicted to enable acyl binding activity and acyl carrier activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Is an ortholog of human NDUFAB1 (NADH:ubiquinone oxidoreductase subunit AB1). WB:WBGene00013238 trap-4 Predicted to be located in endomembrane system. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Iy. Is an ortholog of human SSR4 (signal sequence receptor subunit 4). WB:WBGene00013239 Y56A3A.22 Predicted to be located in mitochondrion. Expressed in gonad; hypodermis; muscle cell; and spermatheca. Is an ortholog of human FAM210A (family with sequence similarity 210 member A). WB:WBGene00013240 Y56A3A.28 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00013241 ung-1 Enables uracil DNA N-glycosylase activity. Involved in base-excision repair. Located in nucleus. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Is an ortholog of human UNG (uracil DNA glycosylase). WB:WBGene00013242 Y56A3A.30 Enriched in several structures, including ABalppppppa; ABplaapappp; ABpraaapppa; amphid neurons; and male distal tip cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including aldicarb; antimycin; and Cadmium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013243 Y56A3A.31 Enriched in ASER; PVR; germline precursor cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and npr-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by five chemicals including rotenone; stavudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF4507) and Integrator complex subunit 15. Is an ortholog of human INTS15 (integrator complex subunit 15). WB:WBGene00013244 Y56A3A.33 Predicted to enable exonuclease activity. Predicted to be located in nucleus. Is an ortholog of human REXO1L1P (REXO1 like 1, pseudogene). WB:WBGene00013246 Y57A10A.1 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including manganese chloride; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00013247 Y57A10A.2 Enriched in ABarppaapp; ABarpppapp; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; elt-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00013248 Y57A10A.3 Enriched in several structures, including I5 neuron; cholinergic neurons; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and microarray studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00013249 Y57A10A.4 Enriched in AIZL; AIZR; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including ced-3; hsf-1; and elt-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including manganese chloride; Alovudine; and stavudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00013250 Y57A10A.5 Enriched in AVA; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including ced-3; dpy-10; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including manganese chloride; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00013251 Y57A10A.6 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and lin-15B based on microarray and RNA-seq studies. Is affected by ten chemicals including manganese chloride; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00013252 Y57A10A.7 Enriched in several structures, including I5 neuron; cholinergic neurons; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and microarray studies. Is affected by several genes including daf-2; age-1; and hsf-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by eleven chemicals including manganese chloride; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00013253 Y57A10A.8 Enriched in PVR; germ line; germline precursor cell; rectal epithelial cell; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-10; npr-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00013254 tag-276 Enriched in AIZL; AIZR; C; germ line; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; methylmercury hydroxide; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00013255 tric-1B.1 Predicted to enable identical protein binding activity and potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human TMEM38A (transmembrane protein 38A). WB:WBGene00013256 Y57A10A.13 Predicted to enable 3'-5' exonuclease activity. Predicted to be involved in nucleobase-containing compound metabolic process and regulation of macromolecule metabolic process. Predicted to be located in cytoplasm and nucleus. WB:WBGene00013257 Y57A10A.14 Enriched in head mesodermal cell and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00013258 polg-1 Predicted to enable 3'-5' exonuclease activity and DNA-directed DNA polymerase activity. Involved in several processes, including defecation; determination of adult lifespan; and mitochondrial DNA replication. Predicted to be located in mitochondrion. Predicted to be part of gamma DNA polymerase complex. Human ortholog(s) of this gene implicated in several diseases, including mitochondrial DNA depletion syndrome (multiple); mitochondrial myopathy (multiple); and ovarian disease (multiple). Is an ortholog of human POLG (DNA polymerase gamma, catalytic subunit). WB:WBGene00013259 trpp-5 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in plasma membrane. Is an ortholog of human TRAPPC5 (trafficking protein particle complex subunit 5). WB:WBGene00013260 rsr-2 Predicted to be involved in RNA splicing and mRNA processing. Located in nuclear speck. Part of chromatin. Expressed in germ line and somatic cell. Human ortholog(s) of this gene implicated in Parkinson's disease and autosomal dominant intellectual developmental disorder. Is an ortholog of human SRRM2 (serine/arginine repetitive matrix 2). WB:WBGene00013261 sinh-1 Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Involved in mesendoderm development. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of TORC2 complex. Is an ortholog of human MAPKAP1 (MAPK associated protein 1). WB:WBGene00013263 txdc-12.1 Predicted to enable oxidoreductase activity. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in breast cancer; pancreatic ductal adenocarcinoma; and pancreatic ductal carcinoma. Is an ortholog of human TXNDC12 (thioredoxin domain containing 12). WB:WBGene00013264 Y57A10A.24 Enriched in amphid socket cell; anterior hypodermis; arc ant V; and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by eight chemicals including manganese chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Lustrin, cysteine-rich repeated domain; Lustrin, cysteine-rich repeated; and Cysteine-rich repeat. WB:WBGene00013265 parn-2 Predicted to enable 3'-5'-RNA exonuclease activity and snRNA binding activity. Predicted to be involved in snRNA 3'-end processing. Predicted to be located in Cajal body and cytoplasm. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 7. Is an ortholog of human TOE1 (target of EGR1, exonuclease). WB:WBGene00013266 Y57A10A.26 Predicted to be located in cytoplasm. Is an ortholog of human FAXC (failed axon connections homolog, metaxin like GST domain containing). WB:WBGene00013267 Y57A10A.27 Enriched in M cell and germ line based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-7 based on tiling array; proteomic; RNA-seq; and microarray studies. Is affected by paraquat and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00013268 tric-1B.2 Predicted to enable identical protein binding activity and potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 14. Is an ortholog of human TMEM38B (transmembrane protein 38B). WB:WBGene00013269 Y57A10A.29 Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone; mitochondrial respiratory chain complex II assembly; and tricarboxylic acid cycle. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in paraganglioma. Is an ortholog of human SDHAF2 (succinate dehydrogenase complex assembly factor 2). WB:WBGene00013270 Y57A10A.31 Predicted to enable ubiquitin binding activity and ubiquitin-protein transferase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of LUBAC complex. Human ortholog(s) of this gene implicated in Gordon Holmes syndrome. Is an ortholog of human RNF216 (ring finger protein 216). WB:WBGene00013272 aqp-12 Predicted to enable water channel activity. Predicted to be involved in water transport. Predicted to be located in plasma membrane. WB:WBGene00013273 marc-5 Predicted to enable MHC protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class II; immune response; and protein polyubiquitination. Predicted to be located in early endosome membrane; late endosome membrane; and lysosome. WB:WBGene00013275 btb-14 Predicted to be located in extracellular region. WB:WBGene00013276 sre-42 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00013277 sre-41 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00013278 Y57A10B.6 Enriched in several structures, including ABalppppppa; ABarpapaaa; ABplaaaaaa; ABplpaaapa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including 1-methylnicotinamide; methylmercuric chloride; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Pes-10. WB:WBGene00013279 Y57A10B.7 Predicted to enable peptidase activity. Predicted to be involved in proteolysis. WB:WBGene00013280 Y57A10C.1 Predicted to be located in membrane. WB:WBGene00013281 sre-27 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in neurons. WB:WBGene00013282 sre-26 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00013283 sre-25 Is affected by clk-1 based on microarray studies. Is affected by Sirolimus and allantoin based on microarray studies. WB:WBGene00013284 daf-22 Enables propanoyl-CoA C-acyltransferase activity. Involved in several processes, including carbohydrate derivative metabolic process; dauer larval development; and positive regulation of developmental process. Located in peroxisome. Expressed in body wall musculature; hypodermis; intestine; and neurons. Used to study obesity. Human ortholog(s) of this gene implicated in Zellweger syndrome. Is an ortholog of human SCP2 (sterol carrier protein 2). WB:WBGene00013285 dct-12 Enriched in ADEL; ADER; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on tiling array; microarray; proteomic; and RNA-seq studies. Is affected by Chlorpyrifos; Diazinon; and Microcystin-LR based on microarray studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class bc (Srbc) and Serpentine type 7TM GPCR chemoreceptor Srbc. WB:WBGene00013286 Y57A10C.8 Predicted to be located in membrane. WB:WBGene00013287 Y57A10C.9 Predicted to be located in membrane. WB:WBGene00013288 Y57A10C.10 Predicted to be located in membrane. WB:WBGene00013289 tag-273 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Predicted to be located in actin cytoskeleton and plasma membrane. Is an ortholog of human LIMA1 (LIM domain and actin binding 1). WB:WBGene00013290 Y57G11A.2 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00013292 Y57G11A.4 Predicted to be involved in regulation of glutamate receptor signaling pathway. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 37. Is an ortholog of human FRRS1 (ferric chelate reductase 1) and FRRS1L (ferric chelate reductase 1 like). WB:WBGene00013293 Y57G11A.5 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nuclear speck. WB:WBGene00013294 pals-30 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Mercuric Chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013295 Y57G11B.2 Enriched in several structures, including ASER; head mesodermal cell; pharyngeal cell; pharyngeal-intestinal valve; and spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Cadmium Chloride; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00013296 Y57G11B.3 Enriched in neurons and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Mercuric Chloride; manganese chloride; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00013297 Y57G11B.5 Enriched in anterior spermatheca; cephalic sheath cell; dopaminergic neurons; hypodermis; and posterior spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including Ethanol; 1-methylnicotinamide; and nicotinic acid based on RNA-seq; microarray; and proteomic studies. WB:WBGene00013298 Y57G11B.6 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; ABalappppaa; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including prg-1; mex-3; and mex-1 based on RNA-seq and microarray studies. Is affected by Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00013299 irld-18 Predicted to be located in membrane. WB:WBGene00013300 lgc-7 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in irritable bowel syndrome. Is an ortholog of human HTR3A (5-hydroxytryptamine receptor 3A) and HTR3E (5-hydroxytryptamine receptor 3E). WB:WBGene00013301 Y57G11C.3 Predicted to enable 6-phosphogluconolactonase activity. Predicted to be involved in pentose-phosphate shunt, oxidative branch. Located in nucleus. Expressed in germ cell. Is an ortholog of human PGLS (6-phosphogluconolactonase). WB:WBGene00013302 vti-1 Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in macroautophagy and vesicle-mediated transport. Predicted to be located in endomembrane system. Predicted to be part of SNARE complex. Is an ortholog of human VTI1A (vesicle transport through interaction with t-SNAREs 1A). WB:WBGene00013303 Y57G11C.5 Enriched in XXX cell; head neurons; sensory neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Serpin superfamily. WB:WBGene00013304 ptp-5.2 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00013305 Y57G11C.7 Is affected by several genes including daf-12; lin-15B; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies. WB:WBGene00013306 Y57G11C.8 Enriched in MSpppaaa; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Ethanol; manganese chloride; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cyclin-like superfamily. WB:WBGene00013307 melo-1 Predicted to enable RNA binding activity. Predicted to be involved in negative regulation of gene expression, epigenetic and protein localization to heterochromatin. Predicted to be located in nucleoplasm. Is an ortholog of human PPHLN1 (periphilin 1). WB:WBGene00013308 nuo-3 Predicted to be involved in response to oxidative stress. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease and nuclear type mitochondrial complex I deficiency 33. Is an ortholog of human NDUFA6 (NADH:ubiquinone oxidoreductase subunit A6). WB:WBGene00013310 Y57G11C.14 Enriched in MSpaapaa; germ line; somatic gonad precursor; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and bisphenol S based on microarray; RNA-seq; and proteomic studies. WB:WBGene00013311 sec-61.A Predicted to enable protein transmembrane transporter activity; ribosome binding activity; and signal sequence binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation and post-translational protein targeting to membrane, translocation. Predicted to be located in membrane. Predicted to be part of Sec61 translocon complex. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Is an ortholog of human SEC61A1 (SEC61 translocon subunit alpha 1) and SEC61A2 (SEC61 translocon subunit alpha 2). WB:WBGene00013312 hhat-2 Predicted to enable palmitoyltransferase activity. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in chondrodysplasia-pseudohermaphroditism syndrome. Is an ortholog of human HHAT (hedgehog acyltransferase). WB:WBGene00013313 Y57G11C.18 Enriched in AVK; OLL; PVD; neurons; and sensory neurons based on microarray and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by Sodium Chloride; Rifampin; and Atrazine based on RNA-seq and microarray studies. WB:WBGene00013314 Y57G11C.19 No description available WB:WBGene00013315 Y57G11C.20 Expressed in intestine. WB:WBGene00013316 Y57G11C.21 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; alg-1; and drh-3 based on RNA-seq and microarray studies. Is affected by hydrogen sulfide based on microarray studies. WB:WBGene00013317 Y57G11C.22 Enables protein kinase C binding activity. Predicted to be involved in dendritic spine maintenance; protein localization; and regulation of cellular component organization. Predicted to be located in neuron projection; synapse; and trans-Golgi network membrane. Is an ortholog of human PICK1 (protein interacting with PRKCA 1). WB:WBGene00013318 Y57G11C.23 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00013319 ccch-5 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein); ZFP36L1 (ZFP36 ring finger protein like 1); and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00013320 srt-51 Is affected by sir-2.1 based on microarray studies. WB:WBGene00013321 Y57G11C.31 Predicted to enable transferase activity. Predicted to be located in membrane. WB:WBGene00013322 talp-3 Expressed in ciliated neurons. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013323 Y57G11C.33 Predicted to be involved in protein targeting to membrane. Predicted to be located in membrane. Predicted to be part of palmitoyltransferase complex. Is an ortholog of human GOLGA7 (golgin A7) and GOLGA7B (golgin A7 family member B). WB:WBGene00013324 mrps-7 Predicted to enable mRNA binding activity and rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation and ribosomal small subunit assembly. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 34. Is an ortholog of human MRPS7 (mitochondrial ribosomal protein S7). WB:WBGene00013325 Y57G11C.36 Predicted to enable mRNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. WB:WBGene00013326 anoh-2 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Expressed in somatic nervous system; spermatheca; and touch receptor neurons. Is an ortholog of human ANO8 (anoctamin 8). WB:WBGene00013327 Y57G11C.38 Enriched in several structures, including ABprpapppa; AIB; B cell; DVA; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; sek-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including D-glucose; bisphenol A; and metformin based on RNA-seq studies. WB:WBGene00013328 srlf-27 Enriched in several structures, including anterior hypodermis; arcade cell; male distal tip cell; mechanosensory neurons; and pharyngeal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00013329 Y57G11C.40 Enriched in body wall muscle cell from MS lineage; enteric muscle; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including 1-methylnicotinamide; rotenone; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00013330 Y57G11C.41 Enriched in body wall muscle cell and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by Tunicamycin and Colistin based on microarray studies. WB:WBGene00013331 Y57G11C.42 Enriched in several structures, including anterior hypodermis; command interneuron; interfacial epithelial cell; rectal gland cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by fifteen chemicals including 1-methylnicotinamide; D-glucose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00013332 Y57G11C.43 Predicted to enable ATP binding activity. Predicted to be involved in tRNA wobble uridine modification. Is an ortholog of human KTI12 (KTI12 chromatin associated homolog). WB:WBGene00013333 degl-1 Predicted to enable sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00013334 nlp-56 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00013335 Y57G11C.46 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00013336 pnc-2 Enables nicotinamidase activity. Involved in nicotinamide metabolic process. WB:WBGene00013337 Y57G11C.48 Enriched in male based on RNA-seq studies. Is affected by several genes including skn-1; eat-2; and npr-1 based on RNA-seq and tiling array studies. Is affected by ten chemicals including methylmercuric chloride; Rifampin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00013338 lgc-8 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in irritable bowel syndrome. Is an ortholog of human HTR3A (5-hydroxytryptamine receptor 3A) and HTR3E (5-hydroxytryptamine receptor 3E). WB:WBGene00013339 phf-14 Predicted to enable histone binding activity and nucleosome binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human PHF14 (PHD finger protein 14). WB:WBGene00013340 tcc-1 Enables kinesin binding activity. Involved in spindle localization. Located in endoplasmic reticulum membrane. WB:WBGene00013341 Y59A8A.7 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00013343 prp-6 Predicted to be involved in spliceosomal tri-snRNP complex assembly. Predicted to be part of U4/U6 x U5 tri-snRNP complex and catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in retinitis pigmentosa 60. Is an ortholog of human PRPF6 (pre-mRNA processing factor 6). WB:WBGene00013344 ebp-1 Predicted to enable microtubule plus-end binding activity. Predicted to be involved in protein localization to microtubule; regulation of microtubule polymerization or depolymerization; and spindle assembly. Located in cell cortex and microtubule cytoskeleton. Human ortholog(s) of this gene implicated in congenital symmetric circumferential skin creases 2. Is an ortholog of human MAPRE1 (microtubule associated protein RP/EB family member 1); MAPRE2 (microtubule associated protein RP/EB family member 2); and MAPRE3 (microtubule associated protein RP/EB family member 3). WB:WBGene00013345 Y59A8B.8 Predicted to enable soluble NSF attachment protein activity and syntaxin binding activity. Predicted to be involved in intracellular protein transport. Predicted to be part of SNARE complex. Is an ortholog of human NAPG (NSF attachment protein gamma). WB:WBGene00013347 nova-1 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human NOVA1 (NOVA alternative splicing regulator 1). WB:WBGene00013348 fbxa-106 Enriched in germ line; germline precursor cell; head mesodermal cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including hsf-1; elt-2; and clk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; manganese chloride; and levamisole based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013349 Y59A8B.12 Enriched in several structures, including germ line; germline precursor cell; head mesodermal cell; hypodermis; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and npr-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00013350 slr-2 Expressed in intestine. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type and Zinc finger C2H2 superfamily. WB:WBGene00013351 Y59A8B.19 Is affected by several genes including daf-2; clk-1; and vhl-1 based on microarray and tiling array studies. Is affected by Quercetin and single-walled carbon nanotube based on microarray studies. WB:WBGene00013352 lon-8 Involved in nematode male tail tip morphogenesis and regulation of growth. Predicted to be located in extracellular space. Expressed in hyp4; hyp7 syncytium; and intestine. WB:WBGene00013353 Y59A8B.21 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00013354 snx-6 Enables protein self-association. Involved in execution phase of apoptosis and phagosome-lysosome fusion involved in apoptotic cell clearance. Located in early phagosome. Is an ortholog of human SNX32 (sorting nexin 32); SNX5 (sorting nexin 5); and SNX6 (sorting nexin 6). WB:WBGene00013355 gck-3 Enables protein kinase binding activity and protein serine/threonine kinase activity. Involved in epithelial tube morphogenesis; hyperosmotic response; and multicellular organismal-level water homeostasis. Acts upstream of with a positive effect on positive regulation of gene expression. Located in cytoplasm. Expressed in body wall musculature; excretory system; hypodermis; oocyte; and spermatheca. Is an ortholog of human OXSR1 (oxidative stress responsive kinase 1) and STK39 (serine/threonine kinase 39). WB:WBGene00013356 Y59A8B.24 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABplpppaaa; and ABprpaaapa based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; cyc-1; and mir-34 based on microarray; tiling array; and RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00013357 clec-260 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; multi-walled carbon nanotube; and antimycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00013358 abhd-3.1 Predicted to enable acetylesterase activity and acylglycerol lipase activity. Predicted to be involved in medium-chain fatty acid biosynthetic process and medium-chain fatty acid catabolic process. Predicted to be located in membrane. Is an ortholog of human ABHD1 (abhydrolase domain containing 1) and ABHD3 (abhydrolase domain containing 3, phospholipase). WB:WBGene00013359 Y60A3A.8 Enriched in PLML; PLMR; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray; RNA-seq; and tiling array studies. Is affected by ten chemicals including methylmercuric chloride; rotenone; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00013360 tmed-4 Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human TMED4 (transmembrane p24 trafficking protein 4) and TMED9 (transmembrane p24 trafficking protein 9). WB:WBGene00013361 fars-2 Predicted to enable phenylalanine-tRNA ligase activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 14 and hereditary spastic paraplegia 77. Is an ortholog of human FARS2 (phenylalanyl-tRNA synthetase 2, mitochondrial). WB:WBGene00013362 algn-7 Predicted to enable UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ij and congenital myasthenic syndrome 13. Is an ortholog of human DPAGT1 (dolichyl-phosphate N-acetylglucosaminephosphotransferase 1). WB:WBGene00013363 nhr-240 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by several genes including clk-1; smg-2; and etr-1 based on microarray and RNA-seq studies. Is affected by dibromoacetic acid; tetrabromobisphenol A; and dafa#1 based on microarray studies. WB:WBGene00013364 Y60A3A.16 Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00013365 Y60A3A.19 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and vesicle fusion with Golgi apparatus. Predicted to be located in trans-Golgi network. Is an ortholog of human YIPF4 (Yip1 domain family member 4). WB:WBGene00013366 Y60A3A.21 Enriched in hypodermis; muscle cell; neurons; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00013367 Y60A3A.23 Predicted to be located in membrane. WB:WBGene00013368 Y60A9.1 Enriched in neurons based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; his-72; and drh-3 based on microarray; tiling array; and RNA-seq studies. Is affected by stavudine; resveratrol; and Diazinon based on RNA-seq and microarray studies. WB:WBGene00013369 Y60A9.2 Is affected by several genes including daf-2; eat-2; and mut-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013370 Y60A9.3 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein); ZFP36L1 (ZFP36 ring finger protein like 1); and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00013371 Y60A9A.1 Is affected by several genes including clk-1; drh-3; and adr-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00013372 Y61B8B.2 Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00013373 popl-7 Predicted to be involved in intracellular transport and protein secretion. Predicted to be located in Golgi membrane. Is an ortholog of human TMEM167A (transmembrane protein 167A). WB:WBGene00013374 Y62E10A.3 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pmk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00013375 srsx-25 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00013376 Y62E10A.6 Predicted to enable NADPH-adrenodoxin reductase activity. Predicted to be involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Is an ortholog of human FDXR (ferredoxin reductase). WB:WBGene00013378 emc-3 Predicted to be located in membrane. Predicted to be part of EMC complex. Is an ortholog of human EMC3 (ER membrane protein complex subunit 3). WB:WBGene00013379 Y62E10A.13 Predicted to enable magnesium ion binding activity. Predicted to be involved in L-serine biosynthetic process and dephosphorylation. Predicted to be located in cytoplasm. Expressed in head. Human ortholog(s) of this gene implicated in PSPH deficiency. Is an ortholog of human PSPH (phosphoserine phosphatase). WB:WBGene00013380 memi-2 Enriched in ABplpaappa; ABprpaappa; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00013381 cyp-31A5 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Is an ortholog of human CYP4V2 (cytochrome P450 family 4 subfamily V member 2). WB:WBGene00013382 gcl-1 Enables identical protein binding activity. Predicted to be involved in germ cell development. Is an ortholog of human GMCL1 (germ cell-less 1, spermatogenesis associated) and GMCL2 (germ cell-less 2, spermatogenesis associated). WB:WBGene00013383 aptf-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of cell population proliferation and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Expressed in AB lineage cell and C lineage cell. Human ortholog(s) of this gene implicated in branchiooculofacial syndrome and dilated cardiomyopathy. Is an ortholog of human TFAP2A (transcription factor AP-2 alpha). WB:WBGene00013385 Y62E10A.19 Enriched in several structures, including Caaaaa; Caaaap; neurons; rectal epithelial cell; and rectum based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including Ethanol; rotenone; and stavudine based on RNA-seq and microarray studies. WB:WBGene00013386 C12C8.t5 No description available WB:WBGene00013387 Y62F5A.9 Expressed in pharyngeal gland cell. WB:WBGene00013388 Y62F5A.10 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00013389 Y62H9A.1 Predicted to be located in membrane. WB:WBGene00013390 Y62H9A.2 Is affected by prg-1; pmt-2; and qui-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00013391 Y62H9A.3 Enriched in RIM; interneuron; and spermatheca based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by twenty chemicals including Ethanol; 1-methylnicotinamide; and rotenone based on RNA-seq; microarray; and proteomic studies. WB:WBGene00013392 Y62H9A.4 Enriched in anterior spermatheca; germ line; posterior spermatheca; and seam cell based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; proteomic; and RNA-seq studies. Is affected by nineteen chemicals including Lithium Chloride; Heme; and diallyl trisulfide based on microarray; RNA-seq; and proteomic studies. WB:WBGene00013393 Y62H9A.5 Expressed in spermatheca. WB:WBGene00013394 ule-5 Enriched in cephalic sheath cell; germ line; neurons; and spermatheca based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Heme; Ethanol; and rotenone based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013395 Y62H9A.7 Enriched in Z1; Z4; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and ubc-9 based on microarray; tiling array; and RNA-seq studies. Is affected by Tunicamycin and adsorbable organic bromine compound based on microarray studies. WB:WBGene00013396 Y62H9A.8 Enriched in male based on RNA-seq studies. Is affected by several genes including let-60; eat-2; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including aldicarb; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013397 Y62H9A.9 Enriched in ABaraappaa; neurons; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and glh-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00013398 Y62H9A.10 Predicted to be located in membrane. WB:WBGene00013399 Y62H9A.11 Enriched in AFD; ASER; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and aak-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013400 Y62H9A.12 Predicted to be located in membrane. WB:WBGene00013401 Y62H9A.13 Enriched in MSpppaaa; head mesodermal cell; neurons; and in male based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by rotenone based on RNA-seq studies. WB:WBGene00013402 Y62H9A.14 Enriched in XXX cell and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including let-60; clk-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domain: Aspartate decarboxylase-like domain superfamily. WB:WBGene00013403 fbxb-100 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and ciliated neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; rotenone; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00013404 fbxb-101 Enriched in several structures, including ABalaaaala; XXX cell; anterior hypodermis; interfacial epithelial cell; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; methylmercuric chloride; and sesamin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00013405 tdpt-1 Enables identical protein binding activity. Predicted to be involved in double-strand break repair. Predicted to be located in PML body and cytoplasm. Expressed in embryonic cell; somatic cell; and spermatheca. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 23. Is an ortholog of human TDP2 (tyrosyl-DNA phosphodiesterase 2). WB:WBGene00013406 ndua-2 Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease and nuclear type mitochondrial complex I deficiency 13. Is an ortholog of human NDUFA2 (NADH:ubiquinone oxidoreductase subunit A2). WB:WBGene00013407 fld-1 Involved in membrane organization and phospholipid homeostasis. Located in plasma membrane. Expressed widely. Is an ortholog of human TLCD2 (TLC domain containing 2). WB:WBGene00013408 fbxb-93 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalpapaap; AFD; and excretory system based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00013409 fbxb-56 Enriched in several structures, including ABalaaaarl; excretory gland cell; interfacial epithelial cell; neurons; and rect_D based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00013410 fbxb-94 Enriched in body wall musculature based on microarray studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Mercuric Chloride; Rifampin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00013411 Y64G10A.1 Enriched in neurons based on RNA-seq studies. Is affected by several genes including rrf-3; met-2; and mut-2 based on microarray and RNA-seq studies. Is affected by four chemicals including dafa#1; adsorbable organic bromine compound; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domain: Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00013412 Y64G10A.2 Enriched in AVA; AVE; and in male based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; tph-1; and dcr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00013413 Y64G10A.3 No description available WB:WBGene00013414 Y64G10A.5 No description available WB:WBGene00013415 ilcr-1 Predicted to enable interleukin-17 receptor activity. Involved in positive regulation of locomotion and response to oxygen levels. Located in plasma membrane. Part of receptor complex. Expressed in RMGL and RMGR. Human ortholog(s) of this gene implicated in immunodeficiency 51. Is an ortholog of human IL17RA (interleukin 17 receptor A) and IL17RB (interleukin 17 receptor B). WB:WBGene00013416 Y64G10A.7 Predicted to enable calcium ion binding activity and scavenger receptor activity. Predicted to be involved in endocytosis. Predicted to be located in plasma membrane. Is an ortholog of human MEGF6 (multiple EGF like domains 6). WB:WBGene00013417 srab-24 Predicted to be located in membrane. Expressed in AVEL; AVER; AWBL; AWBR; and neurons. WB:WBGene00013418 Y65A5A.1 Enriched in several structures, including ABalpapaap; anterior hypodermis; excretory gland cell; interfacial epithelial cell; and pharyngeal muscle cell based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00013419 Y65A5A.2 Predicted to be located in membrane. WB:WBGene00013421 fbxa-220 Enriched in CEP socket cell; Y cell; and muscle cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including clk-1; pgl-1; and mex-1 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013422 popl-5 Predicted to enable ribonuclease P RNA binding activity and ribonuclease P activity. Predicted to be involved in rRNA processing and tRNA processing. Predicted to be located in nucleolus. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Is an ortholog of human POP5 (POP5 homolog, ribonuclease P/MRP subunit). WB:WBGene00013424 Y66A7A.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including manganese chloride; Sodium Chloride; and antimycin based on RNA-seq and microarray studies. WB:WBGene00013425 ceh-91 Predicted to enable DNA binding activity and chromatin binding activity. Predicted to be involved in chromatin organization and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in dorsal nerve cord; head muscle; and ventral nerve cord. WB:WBGene00013426 Y66A7A.7 Predicted to be located in membrane. WB:WBGene00013427 Y66D12A.1 Enriched in ABplapapppp and ABprapapppp based on single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and glh-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00013428 Y66D12A.2 No description available WB:WBGene00013429 Y66D12A.3 Enriched in amphid sheath cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00013431 ceh-92 Predicted to enable DNA binding activity. WB:WBGene00013432 Y66D12A.6 Enriched in PLM; germ line; germline precursor cell; intestine; and lateral ganglion based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013433 Y66D12A.7 Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be part of glutamyl-tRNA(Gln) amidotransferase complex. Expressed in tail. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 42. Is an ortholog of human GATC (glutamyl-tRNA amidotransferase subunit C). WB:WBGene00013434 Y66D12A.8 Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 107. Is an ortholog of human STEEP1 (STING1 ER exit protein 1). WB:WBGene00013435 psme-3 Predicted to enable endopeptidase activator activity. Predicted to be involved in regulation of G1/S transition of mitotic cell cycle and regulation of proteasomal protein catabolic process. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of proteasome activator complex. Is an ortholog of human PSME3 (proteasome activator subunit 3). WB:WBGene00013436 Y66D12A.10 Enriched in body wall muscle cell; coelomocyte; germ line; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including mianserin; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Human MITD1 enables identical protein binding activity; phosphatidylinositol binding activity; and protein domain specific binding activity. Is predicted to encode a protein with the following domains: MITD1, C-terminal phospholipase D-like domain; MIT domain superfamily; Phospholipase D-like domain at C-terminus of MIT; and MITD1, C-terminal phospholipase D-like domain superfamily. Is an ortholog of human MITD1 (microtubule interacting and trafficking domain containing 1). WB:WBGene00013437 Y66D12A.11 Predicted to be located in membrane. WB:WBGene00013438 ztf-29 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00013439 Y66D12A.13 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00013440 nrps-1 Predicted to enable phosphopantetheine binding activity. Predicted to be involved in amino acid activation for nonribosomal peptide biosynthetic process and secondary metabolite biosynthetic process. Predicted to be located in cytoplasm. Expressed in CANL and CANR. WB:WBGene00013441 xpb-1 Predicted to enable 3'-5' DNA helicase activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be part of nucleotide-excision repair factor 3 complex; transcription factor TFIIH holo complex; and transcription preinitiation complex. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; photosensitive trichothiodystrophy 2; and xeroderma pigmentosum group B. Is an ortholog of human ERCC3 (ERCC excision repair 3, TFIIH core complex helicase subunit). WB:WBGene00013442 Y66D12A.16 Enriched in AVJL; AVJR; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and elt-2 based on RNA-seq; tiling array; and microarray studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013443 such-1 Predicted to be involved in anaphase-promoting complex-dependent catabolic process and positive regulation of mitotic metaphase/anaphase transition. Predicted to be part of anaphase-promoting complex. Expressed in germ line; head neurons; sperm; and vulval precursor cell. Is an ortholog of human ANAPC5 (anaphase promoting complex subunit 5). WB:WBGene00013445 Y66D12A.19 Enriched in ABalpapppa; ABarapappa; XXX cell; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and npr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq studies. WB:WBGene00013446 Y66D12A.21 Predicted to be located in membrane. Is an ortholog of human TM2D1 (TM2 domain containing 1). WB:WBGene00013447 nars-2 Predicted to enable asparagine-tRNA ligase activity. Predicted to be involved in asparaginyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 94 and combined oxidative phosphorylation deficiency 24. Is an ortholog of human NARS2 (asparaginyl-tRNA synthetase 2, mitochondrial). WB:WBGene00013448 Y66D12A.24 Predicted to be located in membrane. WB:WBGene00013449 Y67A6A.1 Enriched in hypodermis; sperm; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00013450 oac-56 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00013451 Y67A10A.2 Enriched in NSM based on tiling array studies. Is affected by several genes including eat-2; clk-1; and tbh-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including aldicarb; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00013452 Y67A10A.3 Predicted to be located in membrane. WB:WBGene00013453 fbxa-83 Enriched in several structures, including ABalpapppa; ABaraappaa; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00013454 fbxa-126 Enriched in NSM and head mesodermal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including eat-2; mex-1; and set-2 based on RNA-seq and microarray studies. Is affected by four chemicals including aldicarb; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00013455 ssu-2 Enriched in muscle cell; neurons; retrovesicular ganglion; and somatic gonad precursor based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including aldicarb; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is an ortholog of human SSUH2 (ssu-2 homolog). WB:WBGene00013456 Y67A10A.7 Predicted to be located in mitochondrion. Is an ortholog of several human genes including ARMCX1 (armadillo repeat containing X-linked 1); ARMCX2 (armadillo repeat containing X-linked 2); and ARMCX3 (armadillo repeat containing X-linked 3). WB:WBGene00013457 paqr-3 Predicted to enable signaling receptor activity. Predicted to be located in membrane. Expressed in excretory duct cell; gonadal sheath cell; rectal gland cell; and vulva. Is an ortholog of human PAQR3 (progestin and adipoQ receptor family member 3). WB:WBGene00013458 clc-8 Predicted to be located in membrane. WB:WBGene00013459 srlf-28 Enriched in AMshL; AMshR; PLM; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including rotenone; D-glucose; and bisphenol A based on RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00013460 cpsf-3 Predicted to enable 5'-3' RNA exonuclease activity; RNA binding activity; and RNA endonuclease activity. Predicted to be involved in mRNA 3'-end processing by stem-loop binding activity and cleavage and mRNA polyadenylation. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Expressed in tail. Is an ortholog of human CPSF3 (cleavage and polyadenylation specific factor 3). WB:WBGene00013461 Y67H2A.2 Predicted to be involved in positive regulation of stress-activated MAPK cascade. Is an ortholog of human KLHDC10 (kelch domain containing 10). WB:WBGene00013462 micu-1 Predicted to enable calcium ion binding activity. Predicted to be involved in calcium import into the mitochondrion and positive regulation of mitochondrial calcium ion concentration. Predicted to be located in mitochondrial inner membrane and mitochondrial intermembrane space. Predicted to be part of uniplex complex. Expressed in PLML; PLMR; germ cell; hypodermal cell; and muscle cell. Used to study neurodegenerative disease. Human ortholog(s) of this gene implicated in myopathy with extrapyramidal signs. Is an ortholog of human MICU1 (mitochondrial calcium uptake 1). WB:WBGene00013463 kdp-1 Located in cytoplasm and nuclear envelope. WB:WBGene00013464 Y67H2A.7 Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide metabolic process and protein processing involved in protein targeting to mitochondrion. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 31. Is an ortholog of human MIPEP (mitochondrial intermediate peptidase). WB:WBGene00013465 Y67H2A.10 Predicted to be located in nucleus. WB:WBGene00013466 srz-47 Predicted to be located in membrane. WB:WBGene00013467 Y68A4A.5 Is affected by cyc-1; rpn-10; and adr-1 based on microarray and RNA-seq studies. Is affected by dafa#1 and Sirolimus based on microarray studies. WB:WBGene00013468 srz-96 Predicted to be located in membrane. WB:WBGene00013469 Y68A4A.10 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and dpy-21 based on RNA-seq and microarray studies. Is affected by Chlorpyrifos based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00013470 clec-243 Is affected by several genes including clk-1; aak-2; and bar-1 based on tiling array; microarray; and RNA-seq studies. Is affected by dibromoacetic acid; dafa#1; and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00013471 clec-242 Is affected by several genes including rrf-3; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including resveratrol; Chlorpyrifos; and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00013472 Y68A4B.3 Enriched in coelomocyte; hypodermis; and ventral nerve cord based on tiling array and single-cell RNA-seq studies. Is affected by several genes including clk-1; daf-19; and set-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Tunicamycin; sucrose; and stearic acid based on microarray and RNA-seq studies. WB:WBGene00013473 Y69E1A.1 Predicted to be located in membrane. WB:WBGene00013474 nsph-3.1 Enriched in NSM; male-specific anatomical entity; and sperm based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirty-six chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Cytosolic motility protein. WB:WBGene00013475 Y69E1A.3 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00013476 Y69E1A.4 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00013477 Y69E1A.5 Enriched in GABAergic neurons; M cell; muscle cell; and sensory neurons based on tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by seventeen chemicals including manganese chloride; D-glucose; and nicotine based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Phosphatidylethanolamine-binding protein, eukaryotic; PEBP-like superfamily; and Phosphatidylethanolamine-binding protein. WB:WBGene00013478 Y69E1A.8 Enriched in ALM; FLP; PLM; and in male based on microarray and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00013479 Y69H2.1 Predicted to be located in membrane. WB:WBGene00013480 egas-3 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00013481 Y69H2.3 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00013482 Y69H2.7 Predicted to enable helicase activity. WB:WBGene00013483 nhr-241 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00013484 Y69H2.9 Predicted to be located in membrane. WB:WBGene00013485 Y69H2.10 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00013486 egas-1 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00013487 egas-2 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00013489 col-42 Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. WB:WBGene00013490 Y70C5A.2 Predicted to be located in membrane. WB:WBGene00013491 Y70C5B.1 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by lin-15B and etr-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00013492 Y70C5C.1 Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis involved in protein catabolic process. Predicted to be located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease; diabetic encephalopathy; and type 2 diabetes mellitus. Is an ortholog of human IDE (insulin degrading enzyme). WB:WBGene00013493 clec-9 Is affected by several genes including skn-1; lin-4; and lin-14 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-three chemicals including aldicarb; tryptophan; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00013494 irld-58 Enriched in neurons based on RNA-seq studies. Is affected by cyc-1 and sir-2.1 based on microarray studies. WB:WBGene00013495 clec-236 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00013496 npr-40 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00013497 hex-5 Enables hexosaminidase activity. Involved in carbohydrate metabolic process. Expressed in head muscle; tail; and vulva. Is an ortholog of human HEXD (hexosaminidase D). WB:WBGene00013498 paml-1 Predicted to be located in membrane. WB:WBGene00013499 Y70G10A.3 Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Expressed in excretory cell and hypodermis. Is an ortholog of human SLCO4A1 (solute carrier organic anion transporter family member 4A1) and SLCO4C1 (solute carrier organic anion transporter family member 4C1). WB:WBGene00013500 Y71A12B.2 Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00013501 Y71A12B.3 Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00013502 clec-111 Is affected by several genes including daf-2; daf-12; and drh-3 based on microarray; tiling array; and RNA-seq studies. Is affected by Atrazine and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; C-type lectin fold; and PAN-3 domain. WB:WBGene00013503 clec-112 Is affected by several genes including clk-1; hpl-2; and hda-1 based on tiling array; microarray; and RNA-seq studies. Is affected by allantoin; Sirolimus; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; and PAN-3 domain. WB:WBGene00013504 Y71A12B.7 No description available WB:WBGene00013505 Y71A12B.8 Enriched in MSaapaapa and MSpapaapa based on single-cell RNA-seq studies. Is affected by several genes including eat-2; nhr-49; and csr-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00013506 usp-3 Predicted to enable cysteine-type deubiquitinase activity and zinc ion binding activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human USP3 (ubiquitin specific peptidase 3). WB:WBGene00013507 Y71A12B.10 Predicted to enable identical protein binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum exit site. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 57. Is an ortholog of human TFG (trafficking from ER to golgi regulator). WB:WBGene00013508 Y71A12B.11 Predicted to be located in membrane. WB:WBGene00013509 Y71A12B.12 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00013510 Y71A12B.13 Enriched in AVK based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00013511 Y71A12B.15 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABplaapaaa; hyp3; and interfacial epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including clk-1; daf-18; and sma-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00013512 nhr-276 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00013513 Y71A12C.2 Predicted to be located in membrane. Is an ortholog of human TMEM41A (transmembrane protein 41A). WB:WBGene00013514 Y73F4A.1 Predicted to be located in extracellular region. WB:WBGene00013515 Y73F4A.2 Predicted to be located in extracellular region. WB:WBGene00013516 Y73F4A.3 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; methylmercuric chloride; and bisphenol A based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: DOMON domain. WB:WBGene00013517 lgc-52 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in SAADL; SAADR; SAAVL; and SAAVR. WB:WBGene00013518 Y73F8A.5 Predicted to be located in membrane. Is an ortholog of human ELAPOR1 (endosome-lysosome associated apoptosis and autophagy regulator 1) and ELAPOR2 (endosome-lysosome associated apoptosis and autophagy regulator family member 2). WB:WBGene00013519 Y73F8A.10 Enriched in male based on RNA-seq studies. Is affected by several genes including csr-1; hpl-2; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00013520 best-21 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). WB:WBGene00013521 Y73F8A.12 Enriched in amphid sheath cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; atracurium; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00013522 Y73F8A.13 Enriched in several structures, including ABalpapaap; ABalpppapa; ABalpppappp; germ line; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00013523 Y73F8A.14 Enriched in amphid sheath cell; hypodermis; and in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; D-glucose; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013524 Y73F8A.15 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Tunicamycin; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00013525 irld-59 Enriched in neurons based on RNA-seq studies. Is affected by several genes including clk-1; nhr-25; and mir-34 based on microarray and RNA-seq studies. Is affected by four chemicals including fluoranthene; Chlorpyrifos; and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00013526 Y73F8A.20 Enriched in FLP; amphid sheath cell; g1AL; g1AR; and in male based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; npr-1; and pgl-1 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Serpin superfamily. WB:WBGene00013527 Y73F8A.22 Enriched in ABarpaaa based on single-cell RNA-seq studies. Is affected by several genes including eat-2; nhr-49; and mex-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00013528 Y73F8A.23 Enriched in tail hypodermis based on single-cell RNA-seq studies. Is affected by several genes including clk-1; set-2; and zip-2 based on tiling array; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00013529 gtf-2H4 Predicted to enable double-stranded DNA binding activity. Predicted to be involved in nucleotide-excision repair. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIH core complex and transcription factor TFIIH holo complex. Expressed in head and tail. Is an ortholog of human GTF2H4 (general transcription factor IIH subunit 4). WB:WBGene00013530 ntl-11 Predicted to be involved in regulatory ncRNA-mediated gene silencing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of CCR4-NOT complex. Is an ortholog of human CNOT11 (CCR4-NOT transcription complex subunit 11). WB:WBGene00013531 Y73F8A.26 Predicted to contribute to collagen binding activity. Predicted to be involved in collagen fibril organization. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 7 and osteogenesis imperfecta type 8. Is an ortholog of human CRTAP (cartilage associated protein) and P3H4 (prolyl 3-hydroxylase family member 4 (inactive)). WB:WBGene00013532 Y73F8A.27 Predicted to enable electron transfer activity. Predicted to be involved in electron transport chain. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial myopathy. Is an ortholog of human FDX2 (ferredoxin 2). WB:WBGene00013533 Y73F8A.29 No description available WB:WBGene00013534 acr-24 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00013535 gyg-3 Is affected by several genes including sek-1; isp-1; and atfs-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; rotenone; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00013536 Y73F8A.32 Enriched in AMsoL and AMsoR based on single-cell RNA-seq studies. Is affected by several genes including cep-1; sod-2; and dpy-21 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013537 Y73F8A.33 Is affected by several genes including alg-1; mex-1; and smg-2 based on RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013538 ari-1.4 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1). WB:WBGene00013539 Y73F8A.35 Predicted to be located in membrane. WB:WBGene00013540 cest-12 Enriched in Psub1; alimentary muscle; pharynx; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Carboxylesterase family; Carboxylesterase, type B; and Phosphorylation site. WB:WBGene00013541 lonp-2 Predicted to enable ATP binding activity; ATP hydrolysis activity; and peptidase activity. Predicted to be involved in protein processing and protein targeting to peroxisome. Predicted to be located in peroxisomal matrix. Is an ortholog of human LONP2 (lon peptidase 2, peroxisomal). WB:WBGene00013542 lron-12 Predicted to enable potassium channel activator activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. WB:WBGene00013543 Y75B8A.6 Predicted to enable nuclear localization sequence binding activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in nucleocytoplasmic transport. Predicted to be part of nuclear pore. WB:WBGene00013544 Y75B8A.7 Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of Mpp10 complex and small-subunit processome. Is an ortholog of human MPHOSPH10 (M-phase phosphoprotein 10). WB:WBGene00013545 Y75B8A.8 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; NSM; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013547 Y75B8A.10 Predicted to enable metal ion binding activity. WB:WBGene00013548 lury-1 Enables neuropeptide receptor binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of feeding behavior; and positive regulation of egg-laying behavior. Predicted to be located in extracellular region. Expressed in M1 neuron; M2L; M2R; and coelomocyte. WB:WBGene00013549 Y75B8A.13 Enriched in NSM; arcade cell; germ line; and pharyngeal-intestinal valve cell based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by silicon dioxide nanoparticle and paraquat based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013550 gex-4 Predicted to enable GTPase activity. Is an ortholog of human GPN3 (GPN-loop GTPase 3). WB:WBGene00013551 gphr-1 Predicted to enable voltage-gated monoatomic anion channel activity. Predicted to be involved in intracellular pH reduction. Predicted to be located in Golgi cisterna membrane. Is an ortholog of human GPR89A (G protein-coupled receptor 89A) and GPR89B (G protein-coupled receptor 89B). WB:WBGene00013552 gmn-1 Enables DNA-binding transcription factor binding activity. Involved in negative regulation of DNA replication and negative regulation of cell cycle. Predicted to be located in cytoplasm and nucleus. WB:WBGene00013553 Y75B8A.18 Enriched in several structures, including ABalaaaala; GLR; ciliated neurons; germ line; and pharyngeal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including age-1; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; rotenone; and mianserin based on microarray and RNA-seq studies. WB:WBGene00013554 Y75B8A.19 Predicted to enable transferase activity. WB:WBGene00013555 fbxa-89 Enriched in AVDL; AVDR; and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including pmk-1; npr-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including multi-walled carbon nanotube; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00013556 Y75B8A.23 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00013557 Y75B8A.24 Predicted to enable 1-phosphatidylinositol 4-kinase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and phosphatidylinositol-mediated signaling. Predicted to be located in cytoplasm and plasma membrane. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 84. Is an ortholog of human PI4KA (phosphatidylinositol 4-kinase alpha). WB:WBGene00013558 Y75B8A.25 Enriched in several structures, including ABalpapppa; ABaraappaa; NSM; germ line; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; hsf-1; and sir-2.1 based on RNA-seq; proteomic; and microarray studies. Is affected by five chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00013559 Y75B8A.28 Enriched in MSaapapa; MSpapapa; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including Heme; D-glucose; and nanoparticle based on microarray and RNA-seq studies. WB:WBGene00013560 zip-12 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including 1-methylnicotinamide; levamisole; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00013561 Y75B8A.31 Predicted to contribute to siRNA binding activity. Predicted to be involved in regulatory ncRNA-mediated heterochromatin formation. Predicted to be located in nucleus. Is an ortholog of human ARB2A (ARB2 cotranscriptional regulator A). WB:WBGene00013562 Y75B8A.32 Enriched in AFD; OLL; PVD; and intestine based on microarray and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; Sodium Chloride; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00013563 Y75B8A.33 Predicted to be located in membrane. WB:WBGene00013564 Y75B8A.34 Predicted to be located in membrane. WB:WBGene00013565 Y75B8A.37 Enriched in DA neuron and VA neuron based on tiling array studies. Is affected by several genes including alg-1; hpl-2; and his-24 based on microarray and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies. WB:WBGene00013566 Y75B12A.2 Predicted to be located in membrane. WB:WBGene00013567 Y75B12B.1 Enriched in germ line; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain and HTH domain in Mos1 transposase. WB:WBGene00013568 Y75B12B.3 Enriched in interneuron; intestine; rectal epithelial cell; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00013569 bath-36 Enriched in body wall muscle cell; germ line; head mesodermal cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00013570 Y75B12B.8 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including mianserin; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00013571 str-266 Is affected by sir-2.1 and rrf-3 based on microarray studies. Is affected by Atrazine; cadmium; and Sirolimus based on microarray studies. WB:WBGene00013572 Y75B12B.10 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00013573 Y75B12B.11 Enriched in seam cell and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00013574 lron-13 Enriched in neurons; pharynx; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00013575 acs-5 Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Expressed in hypodermis. Human ortholog(s) of this gene implicated in congenital diarrhea. Is an ortholog of human ACSL5 (acyl-CoA synthetase long chain family member 5). WB:WBGene00013576 Y76A2B.4 Predicted to be located in membrane. WB:WBGene00013577 Y76A2B.5 Predicted to be involved in cobalamin metabolic process. Predicted to be located in mitochondrion. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblD. Is an ortholog of human MMADHC (metabolism of cobalamin associated D). WB:WBGene00013578 scav-2 Predicted to enable scavenger receptor activity. Predicted to be involved in endocytosis. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); myeloproliferative neoplasm (multiple); and myositis (multiple). Is an ortholog of human SCARB1 (scavenger receptor class B member 1). WB:WBGene00013579 Y79H2A.2 Predicted to be located in membrane. WB:WBGene00013580 Y79H2A.3 Enriched in ABalppappa; ABarappppa; germ line; intestine; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including rotenone; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013581 Y79H2A.4 Predicted to enable nucleic acid binding activity. WB:WBGene00013583 ceh-51 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in mesodermal cell fate specification; muscle cell fate specification; and pharyngeal muscle development. Located in nucleus. Expressed in several structures, including MSaa; MSap; MSp; MSpa; and MSpp. WB:WBGene00013584 nhr-243 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00013585 cyp-42A1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Is an ortholog of human CYP4V2 (cytochrome P450 family 4 subfamily V member 2). WB:WBGene00013586 Y80D3A.8 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00013587 hrg-10 Predicted to be involved in Golgi organization and protein secretion. Predicted to be located in Golgi apparatus. Is an ortholog of human TANGO2 (transport and golgi organization 2 homolog). WB:WBGene00013588 nlp-42 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00013589 Y80D3A.11 Is affected by several genes including daf-16; skn-1; and hpl-2 based on RNA-seq studies. Is affected by allantoin and Sirolimus based on RNA-seq studies. WB:WBGene00013590 Y81G3A.1 Enriched in germ line; intestine; and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Cry5B; paraquat; and Acrylamide based on microarray and RNA-seq studies. WB:WBGene00013591 gcn-2 Predicted to enable eukaryotic translation initiation factor 2alpha kinase activity. Involved in several processes, including determination of adult lifespan; mitochondrial unfolded protein response; and positive regulation of protein modification process. Acts upstream of with a positive effect on positive regulation of gene expression. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in pulmonary venoocclusive disease 2. Is an ortholog of human EIF2AK4 (eukaryotic translation initiation factor 2 alpha kinase 4). WB:WBGene00013592 Y81G3A.4 Enriched in PLM; Z1; Z4; hypodermis; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercury hydroxide; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00013593 Y87G2A.1 Enriched in ABplpppppp; ABprpppppp; germ line; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; sir-2.1; and npr-1 based on RNA-seq; proteomic; and microarray studies. Is affected by seven chemicals including mianserin; Zidovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013594 Y87G2A.2 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid catabolic process. Predicted to be located in peroxisomal matrix. Is an ortholog of human ACOT8 (acyl-CoA thioesterase 8). WB:WBGene00013595 atg-4.1 Enables cysteine-type endopeptidase activity. Involved in aggrephagy and protein processing. Located in cytoplasm. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; head muscle; and somatic nervous system. Is an ortholog of human ATG4A (autophagy related 4A cysteine peptidase). WB:WBGene00013596 nyn-2 Involved in siRNA processing. WB:WBGene00013597 gpi-1 Predicted to enable glucose-6-phosphate isomerase activity and monosaccharide binding activity. Predicted to be involved in gluconeogenesis; glucose 6-phosphate metabolic process; and glycolytic process. Predicted to be located in cytosol. Expressed in head. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in several diseases, including congenital nonspherocytic hemolytic anemia; leukemia (multiple); and neuromuscular disease. Is an ortholog of human GPI (glucose-6-phosphate isomerase). WB:WBGene00013598 vps-28 Involved in receptor catabolic process. Part of ESCRT I complex. Is an ortholog of human VPS28 (VPS28 subunit of ESCRT-I). WB:WBGene00013599 eipr-1 Involved in positive regulation of dense core granule transport; positive regulation of egg-laying behavior; and positive regulation of locomotion involved in locomotory behavior. Predicted to be located in cytoplasm. Is an ortholog of human EIPR1 (EARP complex and GARP complex interacting protein 1). WB:WBGene00013600 Y87G2A.12 No description available WB:WBGene00013601 Y87G2A.13 Predicted to be located in membrane. Is an ortholog of human TMEM161A (transmembrane protein 161A). WB:WBGene00013602 Y87G2A.16 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00013603 soem-1 Expressed in PQR. Human SHB enables phosphotyrosine residue binding activity. Is predicted to encode a protein with the following domains: SH2 domain and SH2 domain superfamily. Is an ortholog of human SHB (SH2 domain containing adaptor protein B). WB:WBGene00013604 Y87G2A.18 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00013605 Y95D11A.1 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. WB:WBGene00013606 cand-1 Involved in regulation of protein deneddylation. Located in nucleus. Expressed widely. Used to study cancer. Human ortholog(s) of this gene implicated in atrial fibrillation. Is an ortholog of human CAND1 (cullin associated and neddylation dissociated 1) and CAND2 (cullin associated and neddylation dissociated 2 (putative)). WB:WBGene00013607 clec-27 Predicted to be located in membrane. WB:WBGene00013608 clec-35 Predicted to be located in membrane. WB:WBGene00013609 clec-37 Predicted to be located in membrane. WB:WBGene00013610 fbxa-206 Enriched in germ line; germline precursor cell; head mesodermal cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; Sirolimus; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013611 Y102A5C.2 Enriched in several structures, including ABalppappa; ABarappppa; germ line; head mesodermal cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; elt-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00013612 fbxa-207 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by stavudine and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013613 Y102A5C.4 Is affected by several genes including clk-1; pgl-1; and daf-18 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Alovudine; Sodium Chloride; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF684) and Protein of unknown function DUF684. WB:WBGene00013614 clec-237 Is affected by several genes including daf-2; let-60; and sir-2.1 based on microarray and RNA-seq studies. Is affected by aldicarb based on microarray studies. WB:WBGene00013615 fbxa-110 Is affected by several genes including mex-3; mex-1; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine based on microarray studies. WB:WBGene00013616 fbxa-148 Is affected by several genes including pgl-1; lin-15B; and fbf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride and Chlorpyrifos based on microarray studies. WB:WBGene00013617 fbxa-204 Is affected by clk-1 and dlc-1 based on microarray and RNA-seq studies. Is affected by fluoranthene and nitroguanidine based on microarray studies. WB:WBGene00013618 fbxa-205 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00013619 fbxa-112 Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00013620 fbxa-111 Enriched in AFD based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by tryptophan; methylmercuric chloride; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013621 clec-239 Enriched in AFD; NSM; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including pmk-1; clk-1; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Tunicamycin and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00013622 clec-238 Predicted to be located in membrane. WB:WBGene00013623 fbxa-90 Enriched in several structures, including G2; W cell; neurons; retrovesicular ganglion; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including age-1; eat-2; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including methylmercuric chloride; paraquat; and bortezomib based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and Phosphorylation site. WB:WBGene00013624 srbc-80 Is affected by several genes including lin-4; eat-2; and lin-14 based on RNA-seq and microarray studies. Is affected by Sirolimus based on RNA-seq studies. WB:WBGene00013625 srz-53 Is affected by rsr-2 and mir-34 based on tiling array and microarray studies. Is affected by resveratrol; cadmium; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00013626 srz-54 Predicted to be located in membrane. Expressed in ASIL; ASIR; PVT; intestine; and pharynx. WB:WBGene00013627 srz-52 Is affected by sir-2.1 and ain-1 based on microarray studies. WB:WBGene00013628 Y102A5C.27 Enriched in DA neuron; NSM; VA neuron; and body wall muscle cell based on tiling array studies. Is affected by cyc-1 and rsr-2 based on microarray and tiling array studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00013629 srz-95 Predicted to be located in membrane. WB:WBGene00013630 Y102A5D.1 No description available WB:WBGene00013631 Y102F5A.1 Is affected by several genes including eat-2; mir-34; and xpf-1 based on microarray and RNA-seq studies. Is affected by cadmium based on microarray studies. WB:WBGene00013632 Y105C5A.1 Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of histone deacetylase complex and transcription regulator complex. WB:WBGene00013633 Y105C5A.8 Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by sixteen chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00013634 Y105C5A.9 Enriched in intestine based on RNA-seq and microarray studies. Is affected by several genes including skn-1; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013635 Y105C5A.10 Enriched in ABplpapppa and NSM based on tiling array and single-cell RNA-seq studies. Is affected by age-1 and spn-4 based on microarray and RNA-seq studies. WB:WBGene00013636 Y105C5A.12 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including copper sulfate; methylmercury hydroxide; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00013637 Y105C5A.13 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; tiling array; and microarray studies. Is affected by seventeen chemicals including copper sulfate; methylmercury hydroxide; and rotenone based on microarray and RNA-seq studies. WB:WBGene00013638 Y105C5A.14 Enriched in several structures, including body wall muscle cell; excretory cell; germ line; neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00013639 Y105C5A.15 Predicted to enable metal ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in pharynx. WB:WBGene00013640 Y105C5A.17 Enriched in head mesodermal cell and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; clk-1; and hpl-2 based on microarray and RNA-seq studies. Is affected by four chemicals including Tunicamycin; multi-walled carbon nanotube; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. WB:WBGene00013642 daf-38 Enables protein heterodimerization activity. Involved in G protein-coupled receptor signaling pathway involved in dauer larval development. Predicted to be located in plasma membrane. Expressed in chemosensory neurons and head neurons. WB:WBGene00013643 Y105C5A.24 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including autophagy; axon extension; and positive regulation of autophagy. Predicted to be located in autophagosome; cytosol; and phagophore assembly site membrane. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); frontometaphyseal dysplasia 2; and intrinsic cardiomyopathy (multiple). Is an ortholog of human MAP3K7 (mitogen-activated protein kinase kinase kinase 7). WB:WBGene00013644 Y105C5A.25 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including manganese chloride; Sodium Chloride; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00013645 Y105C5B.1 Predicted to be located in membrane. WB:WBGene00013646 Y105C5B.3 Predicted to enable acid phosphatase activity and metal ion binding activity. WB:WBGene00013647 Y105C5B.5 Enriched in cephalic sheath cell and excretory system based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; pie-1; and hsf-1 based on RNA-seq; proteomic; tiling array; and microarray studies. Is affected by twenty-one chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4440; Domain of unknown function (DUF4440); and NTF2-like domain superfamily. WB:WBGene00013648 Y105C5B.7 Is affected by several genes including hsf-1; eat-2; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Heme; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00013649 Y105C5B.8 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00013650 Y105C5B.9 Predicted to enable dioxygenase activity and metal ion binding activity. Is an ortholog of human PHYHD1 (phytanoyl-CoA dioxygenase domain containing 1). WB:WBGene00013651 Y105C5B.11 Predicted to enable metal ion binding activity. Predicted to be involved in innate immune response. WB:WBGene00013652 sams-2 Enriched in NSM; OLL; PVD; and germ line based on proteomic; microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including methylmercuric chloride; stavudine; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013653 ifas-3 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament polymerization. Predicted to be located in actin cytoskeleton. WB:WBGene00013654 Y105C5B.15 Predicted to enable acid phosphatase activity and metal ion binding activity. WB:WBGene00013655 lgc-19 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00013656 Y105C5B.17 Predicted to be located in membrane. WB:WBGene00013657 Y105C5B.18 Enriched in body wall muscle cell and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on tiling array; microarray; and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00013658 Y105C5B.19 Predicted to be located in cytoskeleton. Expressed widely. WB:WBGene00013659 Y105C5B.20 Enriched in several structures, including ABarpapaapp; I5 neuron; cephalic sheath cell; cholinergic neurons; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; rotenone; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00013660 Y105C5B.22 No description available WB:WBGene00013661 Y105C5B.23 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including bar-1; alg-1; and csr-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00013662 Y105C5B.25 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00013663 Y105C5B.26 No description available WB:WBGene00013664 Y105C5B.27 No description available WB:WBGene00013665 hlh-32 Predicted to enable DNA-binding transcription factor activity and E-box binding activity. Predicted to be involved in neuron differentiation; positive regulation of transcription by RNA polymerase II; and sensory organ development. Predicted to be located in nucleus. Is an ortholog of human BHLHE22 (basic helix-loop-helix family member e22). WB:WBGene00013666 Y105E8A.1 Predicted to be located in cytoplasm. Expressed in head and intestine. Is an ortholog of human SH3BGR (SH3 domain binding glutamate rich protein). WB:WBGene00013667 Y105E8A.2 Predicted to be involved in retrograde protein transport, ER to cytosol and ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum lumen. Is an ortholog of human ERLEC1 (endoplasmic reticulum lectin 1). WB:WBGene00013668 slc-30A5 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion import into Golgi lumen. Located in endoplasmic reticulum. Is an ortholog of human SLC30A5 (solute carrier family 30 member 5). WB:WBGene00013669 tcab-1 Predicted to enable RNA binding activity. Predicted to be involved in Cajal body organization. Predicted to be located in Cajal body. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive dyskeratosis congenita 3; carcinoma (multiple); and rectal benign neoplasm. Is an ortholog of human WRAP53 (WD repeat containing antisense to TP53). WB:WBGene00013670 hpo-13 Predicted to enable beta-glucosidase activity. Predicted to be involved in carbohydrate metabolic process and glucosylceramide catabolic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 46. Is an ortholog of human GBA2 (glucosylceramidase beta 2). WB:WBGene00013671 Y105E8A.11 Predicted to be involved in protein maturation by [4Fe-4S] cluster transfer. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 2. Is an ortholog of human BOLA3 (bolA family member 3). WB:WBGene00013672 catp-1 Predicted to enable P-type sodium:potassium-exchanging transporter activity. Involved in dauer larval development. Predicted to be located in plasma membrane. WB:WBGene00013673 Y105E8A.13 Enriched in several structures, including ADE sheath cell; anterior ganglion; anterior hypodermis; arc ant V; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00013674 Y105E8A.14 Predicted to enable poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in intestine; marginal cell; pharyngeal muscle cell; and rectal gland cell. Is an ortholog of human RNF146 (ring finger protein 146). WB:WBGene00013676 ekl-4 Predicted to enable transcription corepressor activity. Involved in negative regulation of cell fate specification. Predicted to be located in chromosome and nucleus. Predicted to be part of NuA4 histone acetyltransferase complex and Swr1 complex. Is an ortholog of human DMAP1 (DNA methyltransferase 1 associated protein 1). WB:WBGene00013677 yars-1 Predicted to enable ATP binding activity and tyrosine-tRNA ligase activity. Predicted to be involved in tyrosyl-tRNA aminoacylation. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate C. Is an ortholog of human YARS1 (tyrosyl-tRNA synthetase 1). WB:WBGene00013678 Y105E8A.20 Predicted to enable methionine-tRNA ligase activity. Predicted to be involved in methionyl-tRNA aminoacylation. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 25 and spastic ataxia 3. Is an ortholog of human MARS2 (methionyl-tRNA synthetase 2, mitochondrial). WB:WBGene00013679 Y105E8A.21 Enriched in AFD; ASER; AVK; germ line; and germline precursor cell based on RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and pmk-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including D-glucose; Zidovudine; and allantoin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: WD40-repeat-containing domain superfamily and Phosphorylation site. WB:WBGene00013680 rpom-1 Predicted to enable DNA-directed 5'-3' RNA polymerase activity and mitochondrial promoter sequence-specific DNA binding activity. Predicted to be involved in mitochondrial transcription. Predicted to be part of mitochondrial DNA-directed RNA polymerase complex. Expressed in several structures, including intestine; muscle cell; nerve ring; oocyte; and vulva. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 55. Is an ortholog of human POLRMT (RNA polymerase mitochondrial). WB:WBGene00013682 Y105E8A.25 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of Rho protein signal transduction. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with midbrain and hindbrain malformations. Is an ortholog of human ARHGEF2 (Rho/Rac guanine nucleotide exchange factor 2). WB:WBGene00013683 zoo-1 Predicted to enable cell adhesion molecule binding activity. Involved in actin filament organization; embryo development; and embryonic morphogenesis. Located in adherens junction and bicellular tight junction. Human ortholog(s) of this gene implicated in biliary tract cancer (multiple); disease of metabolism; and progressive familial intrahepatic cholestasis 4. Is an ortholog of human TJP2 (tight junction protein 2). WB:WBGene00013684 Y105E8A.27 Predicted to be located in membrane. WB:WBGene00013685 Y105E8A.28 Enriched in several structures, including ABalpppappp; ABplapapppp; ABpraaaappp; AFD; and interneuron based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; Sodium Chloride; and Psoralens based on RNA-seq studies. WB:WBGene00013687 exoc-8 Predicted to be involved in Golgi to plasma membrane transport and protein localization. Predicted to be located in cellular anatomical entity. Predicted to be part of exocyst. Expressed in PVDL and PVDR. Is an ortholog of human EXOC8 (exocyst complex component 8). WB:WBGene00013688 riok-2 Predicted to enable protein kinase activity. Involved in nematode larval development. Predicted to be located in cytosol and nucleus. Predicted to be part of preribosome, small subunit precursor. Is an ortholog of human RIOK2 (RIO kinase 2). WB:WBGene00013689 bath-40 Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to be located in cytoplasm and nucleus. WB:WBGene00013690 hprt-1 Enables identical protein binding activity. Predicted to be involved in purine-containing compound metabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in HRPT-related hyperuricemia and Lesch-Nyhan syndrome. Is an ortholog of human PRTFDC1 (phosphoribosyl transferase domain containing 1). WB:WBGene00013691 Y105E8B.6 Enriched in several structures, including ABplpppaapa; ABprpppaapa; germ line; germline precursor cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; elt-2; and pgl-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by stavudine; silicon dioxide nanoparticle; and paraquat based on RNA-seq and microarray studies. WB:WBGene00013692 Y105E8B.7 Predicted to enable histone binding activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Is an ortholog of human MLLT1 (MLLT1 super elongation complex subunit) and MLLT3 (MLLT3 super elongation complex subunit). WB:WBGene00013693 Y105E8B.9 Predicted to enable beta-glucuronidase activity and carbohydrate binding activity. Predicted to be involved in glucuronoside catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in Sly syndrome. Is an ortholog of human GUSB (glucuronidase beta). WB:WBGene00013694 mekk-3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Located in sarcoplasmic reticulum. WB:WBGene00013695 epg-8 Involved in macroautophagy; positive regulation of autophagy; and positive regulation of embryonic development. Located in cytoplasm. Expressed in neurons and pharyngeal muscle cell. WB:WBGene00013696 Y106G6A.4 Enriched in several structures, including anterior hypodermis; excretory cell; male distal tip cell; somatic gonad precursor; and sperm based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Ethanol; methylmercuric chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily. WB:WBGene00013697 dsbn-1 Involved in endosomal transport. Predicted to be part of BLOC-1 complex. Used to study Hermansky-Pudlak syndrome. WB:WBGene00013698 Y106G6D.1 Enriched in ABplpapapa; ABprpapapa; Caapa; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; stavudine; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013699 Y106G6D.2 Enriched in several structures, including ABalppappa; ABarappppa; ABplpaapap; ABprpaapap; and BAG based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; bisphenol A; and bisphenol S based on microarray and RNA-seq studies. WB:WBGene00013700 Y106G6D.3 Enriched in anal depressor muscle; intestinal muscle; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-six chemicals including nicotinic acid; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00013701 Y106G6D.4 Predicted to enable MAP kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and nucleus. WB:WBGene00013702 Y106G6D.6 Enriched in germ line and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including mianserin; procyanidin; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00013703 rbm-12 Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleoplasm. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in schizophrenia 19. Is an ortholog of human RBM12 (RNA binding motif protein 12). WB:WBGene00013704 Y106G6D.8 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; anterior hypodermis; and rect_D based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including rotenone; levamisole; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00013705 Y106G6E.1 Predicted to enable MAP kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and nucleus. WB:WBGene00013706 Y106G6E.2 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00013707 Y106G6E.3 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies. WB:WBGene00013708 Y106G6E.4 Predicted to enable 5-formyltetrahydrofolate cyclo-ligase activity. Predicted to be involved in folic acid-containing compound biosynthetic process and tetrahydrofolate interconversion. Predicted to be located in mitochondrion. Is an ortholog of human MTHFS (methenyltetrahydrofolate synthetase). WB:WBGene00013709 csnk-1 Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including first cell cycle pseudocleavage; regulation of mitotic spindle elongation; and spindle localization. Located in aster; cell cortex; and plasma membrane. Is an ortholog of human CSNK1G3 (casein kinase 1 gamma 3). WB:WBGene00013710 Y106G6G.1 Enriched in neurons and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00013711 Y106G6G.2 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Is an ortholog of human ARFGEF3 (ARFGEF family member 3). WB:WBGene00013712 dlc-6 Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based process. Predicted to be located in cellular anatomical entity. Predicted to be part of cytoplasmic dynein complex. WB:WBGene00013713 Y106G6G.4 Predicted to be located in membrane. WB:WBGene00013714 Y106G6G.5 No description available WB:WBGene00013716 Y106G6H.1 Enriched in head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; bisphenol S; and stavudine based on RNA-seq and microarray studies. WB:WBGene00013717 madf-10 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Expressed in head muscle; head neurons; motor neurons; and ventral nerve cord. WB:WBGene00013718 pdpr-1 Predicted to enable oxidoreductase activity. Predicted to be located in mitochondrial matrix. Is an ortholog of human PDPR (pyruvate dehydrogenase phosphatase regulatory subunit). WB:WBGene00013719 Y106G6H.6 Enriched in ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABprpaaapa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including Aspirin; Zidovudine; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Tetratricopeptide-like helical domain superfamily. WB:WBGene00013720 Y106G6H.8 Predicted to be located in membrane. Is an ortholog of human TMEM256 (transmembrane protein 256). WB:WBGene00013721 Y106G6H.9 Enriched in RIH based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and lin-4 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00013722 Y106G6H.10 Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013723 Y106G6H.13 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00013724 Y106G6H.14 Predicted to be involved in signal transduction. Is an ortholog of human OSTF1 (osteoclast stimulating factor 1). WB:WBGene00013725 ska-1 Enables microtubule binding activity. Predicted to be involved in several processes, including chromosome segregation; mitotic cell cycle; and regulation of microtubule polymerization or depolymerization. Located in kinetochore and mitotic spindle. Is an ortholog of human SKA1 (spindle and kinetochore associated complex subunit 1). WB:WBGene00013726 Y106G6H.16 Predicted to be located in membrane. WB:WBGene00013727 Y111B2A.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleus. Is an ortholog of human CLK1 (CDC like kinase 1). WB:WBGene00013728 Y111B2A.2 Predicted to be located in mitochondrial inner membrane. WB:WBGene00013729 Y111B2A.3 Predicted to enable helicase activity. WB:WBGene00013730 sql-1 Predicted to enable small GTPase binding activity. Predicted to be involved in Golgi organization and endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus. Human ortholog(s) of this gene implicated in achondrogenesis type IA. Is an ortholog of human TRIP11 (thyroid hormone receptor interactor 11). WB:WBGene00013732 aakg-1 Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleotide-activated protein kinase complex. Human ortholog(s) of this gene implicated in Wolff-Parkinson-White syndrome; hypertrophic cardiomyopathy 6; and lethal congenital glycogen storage disease of heart. Is an ortholog of human PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1); PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2); and PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3). WB:WBGene00013734 gldi-8 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00013735 Y111B2A.12 Enriched in several structures, including ABalapppaa; germ line; intestinal muscle; neurons; and rectal muscle based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by eleven chemicals including hydrogen sulfide; rotenone; and bisphenol A based on microarray and RNA-seq studies. Human AAMP enables heparin binding activity. Is predicted to encode a protein with the following domains: WD40 repeat; WD40/YVTN repeat-like-containing domain superfamily; and WD40-repeat-containing domain superfamily. Is an ortholog of human AAMP (angio associated migratory cell protein). WB:WBGene00013736 gtf-2A2 Predicted to enable RNA polymerase II general transcription initiation factor activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIA complex. Is an ortholog of human GTF2A2 (general transcription factor IIA subunit 2). WB:WBGene00013737 tpst-1 Enables protein-tyrosine sulfotransferase activity. Involved in several processes, including collagen metabolic process; cuticle development involved in collagen and cuticulin-based cuticle molting cycle; and regulation of nematode larval development. Located in trans-Golgi network. Expressed in AIYL; AIYR; head neurons; and hypodermis. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Is an ortholog of human TPST1 (tyrosylprotein sulfotransferase 1) and TPST2 (tyrosylprotein sulfotransferase 2). WB:WBGene00013738 elpc-2 Predicted to be involved in tRNA wobble uridine modification. Predicted to be located in cytoplasm and nucleus. Predicted to be part of elongator holoenzyme complex. Expressed in several structures, including body wall musculature; coelomocyte; excretory cell; intestine; and pharynx. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 58. Is an ortholog of human ELP2 (elongator acetyltransferase complex subunit 2). WB:WBGene00013739 spin-4 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 115. Is an ortholog of human SPNS1 (SPNS lysolipid transporter 1, lysophospholipid); SPNS2 (SPNS lysolipid transporter 2, sphingosine-1-phosphate); and SPNS3 (SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)). WB:WBGene00013740 hut-1 Predicted to enable UDP-galactose transmembrane transporter activity and UDP-glucose transmembrane transporter activity. Involved in endoplasmic reticulum organization and nematode larval development. Located in Golgi apparatus and endoplasmic reticulum. Expressed in coelomocyte; egg-laying apparatus; gonad; intestine; and pharyngeal cell. Is an ortholog of human SLC35B1 (solute carrier family 35 member B1). WB:WBGene00013741 Y111B2A.21 Enriched in ABalppappa; ABarappppa; AFD; germ line; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and sek-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00013742 sas-1 Located in centriole. Expressed in sperm. Used to study orofaciodigital syndrome. WB:WBGene00013744 Y111B2A.27 Enriched in Z1.p; Z4.a; gon_male_dtc anterior; and gon_male_dtc posterior based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013746 lgc-55 Enables chloride channel activity. Involved in chloride transport and mechanosensory behavior. Located in neuronal cell body and postsynaptic density. Expressed in GLR; egg-laying apparatus; head muscle; nerve ring; and neurons. WB:WBGene00013747 spe-19 Involved in spermatid development. Predicted to be located in membrane. WB:WBGene00013748 ssu-1 Enables 1-hydroxypyrene sulfotransferase activity and aryl sulfotransferase activity. Involved in sulfur compound metabolic process. Located in cytosol. Expressed in ASJL and ASJR. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); lung non-small cell carcinoma (multiple); and reproductive organ cancer (multiple). Is an ortholog of several human genes including SULT1A1 (sulfotransferase family 1A member 1); SULT1A2 (sulfotransferase family 1A member 2); and SULT1E1 (sulfotransferase family 1E member 1). WB:WBGene00013749 Y113G7A.12 Enriched in NSM; OLL; PVD; and muscle cell based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013750 Y113G7A.13 Enriched in intestine based on RNA-seq studies. Is affected by several genes including glp-1; elt-2; and pgl-1 based on microarray; RNA-seq; and proteomic studies. Is affected by five chemicals including stavudine; paraquat; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00013751 Y113G7A.14 Predicted to be located in membrane. WB:WBGene00013752 nlp-69 Predicted to be involved in neuropeptide signaling pathway. Expressed in head neurons and mechanosensory neurons. WB:WBGene00013753 Y113G7A.16 Enriched in neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013754 fbxa-116 Involved in innate immune response. WB:WBGene00013755 fbxa-115 Enriched in several structures, including intestine; male distal tip cell; neurons; retrovesicular ganglion; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; Alovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013756 ftr-1 Enriched in several structures, including ABplpaapap; ABprpaapap; AFD; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; manganese chloride; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013757 fbxa-113 Is affected by several genes including daf-2; clk-1; and hsp-6 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Alovudine; and Psoralens based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00013758 fbxa-114 Enriched in germ line; germline precursor cell; head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including glp-1; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including manganese chloride; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013759 fbxb-59 Enriched in body wall muscle cell and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including methylmercuric chloride; stavudine; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and Phosphorylation site. WB:WBGene00013760 srbc-34 Predicted to be located in membrane. WB:WBGene00013761 Y113G7B.11 Predicted to be located in membrane. WB:WBGene00013762 Y113G7B.12 Predicted to enable catalytic activity. WB:WBGene00013763 Y113G7B.14 Enriched in head mesodermal cell; intestine; muscle cell; and neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; levamisole; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00013764 Y113G7B.15 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSO (cathepsin O). WB:WBGene00013765 cdkr-3 Involved in IRE1-mediated unfolded protein response. Expressed in neurons; pharynx; and spermatheca. Used to study early infantile epileptic encephalopathy. Is an ortholog of human CDK5RAP3 (CDK5 regulatory subunit associated protein 3). WB:WBGene00013766 prmt-1 Enables S-adenosyl-L-methionine binding activity and protein methyltransferase activity. Involved in several processes, including heat acclimation; positive regulation of protein localization to nucleus; and regulation of dauer entry. Located in cytoplasm. Expressed in head; intestinal cell; pharyngeal cell; ventral nerve cord; and vulval cell. Is an ortholog of human PRMT8 (protein arginine methyltransferase 8). WB:WBGene00013768 sld-5 Predicted to be involved in double-strand break repair via break-induced replication. Located in nucleus. Is an ortholog of human GINS4 (GINS complex subunit 4). WB:WBGene00013770 Y113G7B.26 Is affected by several genes including hpl-2; his-24; and hpl-1 based on RNA-seq and microarray studies. Is affected by Rifampin; allantoin; and tetrabromobisphenol A based on RNA-seq and microarray studies. WB:WBGene00013771 Y113G7C.1 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00013772 clec-192 Is affected by clk-1 based on microarray studies. Is affected by resveratrol; adsorbable organic bromine compound; and Sirolimus based on microarray studies. WB:WBGene00013773 Y116A8A.2 Predicted to be located in cytoskeleton. WB:WBGene00013774 clec-193 Enriched in AVE; body wall muscle cell; neurons; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including prg-1; csr-1; and mex-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including tryptophan; Rifampin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00013775 Y116A8A.4 Enriched in AVA; AVE; NSM; neurons; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Nematode trypsin-6-like family and Chymotrypsin family Peptidase-S1. WB:WBGene00013776 Y116A8A.6 Enriched in AVA; neurons; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Nematode trypsin-6-like family and Chymotrypsin family Peptidase-S1. WB:WBGene00013777 Y116A8A.7 Predicted to be located in cytoskeleton. WB:WBGene00013778 clec-194 Enriched in excretory gland cell and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; pgl-1; and aak-2 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; C-type lectin fold; and PAN-3 domain. WB:WBGene00013779 Y116A8B.1 Enriched in body wall muscle cell; intestine; rectal epithelial cell; and rectum based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; stavudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00013780 Y116A8B.2 No description available WB:WBGene00013781 Y116A8B.4 Enriched in dopaminergic neurons; intestine; and pharyngeal interneuron based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00013782 npr-32 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of human NPBWR1 (neuropeptides B and W receptor 1). WB:WBGene00013783 Y116A8C.1 Is affected by several genes including daf-2; pgl-1; and glh-1 based on tiling array; proteomic; RNA-seq; and microarray studies. Is affected by five chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013784 Y116A8C.3 Expressed in head. WB:WBGene00013785 nep-23 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00013786 nep-24 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00013788 Y116A8C.8 Is affected by several genes including unc-30; drh-3; and slr-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Doxycycline; paraquat; and Atrazine based on RNA-seq and microarray studies. WB:WBGene00013789 Y116A8C.9 Predicted to be located in membrane. Is an ortholog of human TMEM185A (transmembrane protein 185A) and TMEM185B (transmembrane protein 185B). WB:WBGene00013790 Y116A8C.10 Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to be located in endomembrane system. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human RABL3 (RAB, member of RAS oncogene family like 3). WB:WBGene00013791 nccd-1 Is affected by several genes including eat-2; pmk-1; and mir-34 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013792 rad-54.B Predicted to enable DNA translocase activity. Predicted to be involved in double-strand break repair via homologous recombination and reciprocal meiotic recombination. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in colorectal cancer and non-Hodgkin lymphoma. Is an ortholog of human RAD54B (RAD54 homolog B). WB:WBGene00013794 dct-13 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be located in cytosol. Expressed in head muscle; head neurons; intestine; pharyngeal neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein); ZFP36L1 (ZFP36 ring finger protein like 1); and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00013795 nhr-229 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00013796 Y116A8C.19 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be located in cytosol. Expressed in head muscle; intestine; and ventral nerve cord. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein); ZFP36L1 (ZFP36 ring finger protein like 1); and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00013797 Y116A8C.20 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be located in cytosol. Expressed in dorsal nerve cord and ventral nerve cord. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human ZFP36 (ZFP36 ring finger protein); ZFP36L1 (ZFP36 ring finger protein like 1); and ZFP36L2 (ZFP36 ring finger protein like 2). WB:WBGene00013798 clec-195 Is affected by rsr-2; drh-3; and eat-2 based on tiling array and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and PAN-3 domain. WB:WBGene00013799 athp-3 Predicted to enable DNA binding activity and metal ion binding activity. WB:WBGene00013800 Y116A8C.23 Predicted to be located in membrane. WB:WBGene00013801 Y116A8C.24 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. WB:WBGene00013802 Y116A8C.25 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Is an ortholog of human FN3K (fructosamine 3 kinase) and FN3KRP (fructosamine 3 kinase related protein). WB:WBGene00013803 snx-13 Predicted to enable phosphatidylinositol binding activity. Predicted to be located in early endosome. Is an ortholog of human SNX13 (sorting nexin 13). WB:WBGene00013804 Y116A8C.27 Predicted to be involved in mitochondrial proton-transporting ATP synthase complex assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency, nuclear type 1. Is an ortholog of human ATPAF2 (ATP synthase mitochondrial F1 complex assembly factor 2). WB:WBGene00013805 bca-2 Enables carbonate dehydratase activity. Involved in one-carbon metabolic process. WB:WBGene00013806 Y116A8C.29 Predicted to be located in membrane. WB:WBGene00013807 Y116A8C.30 Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 10. Is an ortholog of human NDUFAF2 (NADH:ubiquinone oxidoreductase complex assembly factor 2). WB:WBGene00013808 sfa-1 Predicted to enable mRNA binding activity. Involved in alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human SF1 (splicing factor 1). WB:WBGene00013809 Y116A8C.33 Expressed in intestine. WB:WBGene00013810 Y116A8C.37 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00013811 Y116A8C.38 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. WB:WBGene00013812 Y116A8C.40 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00013814 Y116A8C.43 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-15B based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00013815 Y116A8C.44 Enriched in muscle cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq studies. Is affected by five chemicals including tryptophan; Psoralens; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00013816 Y116F11A.1 Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA helicase activity. Predicted to be involved in DNA duplex unwinding and DNA metabolic process. WB:WBGene00013817 Y116F11A.3 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; AVK; and head neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; cat-2; and csr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Atrazine based on RNA-seq and microarray studies. WB:WBGene00013819 Y116F11A.6 Enriched in several structures, including ABalaaaala; XXX cell; excretory gland cell; muscle cell; and neurons based on microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Death-like domain superfamily. WB:WBGene00013820 Y116F11B.2 Enriched in tail hypodermis based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; clk-1; and aak-2 based on RNA-seq and microarray studies. Is affected by methylmercury hydroxide; manganese chloride; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00013821 srz-35 Is affected by adr-1; qui-1; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00013822 Y116F11B.6 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including paraquat; stearic acid; and bortezomib based on RNA-seq studies. WB:WBGene00013823 Y116F11B.7 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00013824 Y116F11B.8 Enriched in ABplpapppa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including methylmercuric chloride; D-glucose; and metformin based on microarray and RNA-seq studies. WB:WBGene00013825 Y116F11B.9 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00013826 Y116F11B.10 Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Zidovudine; Sirolimus; and metformin based on RNA-seq studies. WB:WBGene00013827 Y116F11B.11 Is affected by several genes including hmg-3; hlh-26; and rsr-2 based on tiling array and RNA-seq studies. Is affected by methylmercuric chloride and Colistin based on microarray studies. WB:WBGene00013828 Y116F11B.13 Is affected by several genes including daf-16; daf-2; and mex-1 based on microarray and RNA-seq studies. Is affected by allantoin; Sirolimus; and cadmium based on RNA-seq and microarray studies. WB:WBGene00013829 Y116F11B.14 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00013830 ZC15.1 Enriched in AVE; AVK; head mesodermal cell; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including silicon dioxide nanoparticle; Oligosaccharides; and resveratrol based on microarray studies. WB:WBGene00013831 clec-262 Enriched in RIH; neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; C-type lectin-like/link domain superfamily; and PAN-3 domain. WB:WBGene00013832 ZC15.3 Enriched in head mesodermal cell and neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00013833 ZC15.5 Predicted to be located in membrane. WB:WBGene00013834 clec-261 Enriched in AVE; F cell; U cell; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by metformin; Sirolimus; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00013835 mlt-4 Involved in ecdysis, collagen and cuticulin-based cuticle. Predicted to be located in ciliary inversin compartment. Expressed in hyp7 syncytium and hypodermis. Human ortholog(s) of this gene implicated in hypertension and nephronophthisis 2. Is an ortholog of human INVS (inversin). WB:WBGene00013836 fbxa-29 Enriched in intestine; rect_D; rect_VL; and rect_VR based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq; tiling array; and microarray studies. Is affected by seven chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013837 fbxa-30 Involved in innate immune response. WB:WBGene00013838 fbxa-31 Enriched in ASER; head mesodermal cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including eat-2; elt-2; and npr-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; D-glucopyranose; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013839 fbxa-32 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including hsf-1; csr-1; and mex-3 based on RNA-seq and microarray studies. Is affected by stavudine; paraquat; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013840 fbxa-151 Involved in innate immune response. WB:WBGene00013841 fbxa-33 Enriched in muscle cell and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including multi-walled carbon nanotube; Sodium Chloride; and allantoin based on RNA-seq studies. WB:WBGene00013842 fbxa-34 Enriched in muscle cell based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Sodium Chloride; and metformin based on RNA-seq studies. WB:WBGene00013843 fbxa-49 Enriched in muscle cell; sensory neurons; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Sodium Chloride; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00013844 fbxa-50 Enriched in hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; procyanidin; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00013845 fbxa-37 Enriched in coelomocyte; germline precursor cell; hypodermis; muscle cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Cadmium Chloride; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00013846 ZC84.1 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00013847 cls-3 Predicted to enable microtubule binding activity. Involved in astral microtubule organization and establishment of mitotic spindle localization. Predicted to be located in basal cortex; kinetochore; and microtubule cytoskeleton. Expressed in neurons and pharyngeal gland cell. Is an ortholog of human CLASP2 (cytoplasmic linker associated protein 2). WB:WBGene00013848 npr-29 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in motor neurons and ventral nerve cord. WB:WBGene00013849 ZC84.6 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00013850 ZC84.7 Predicted to be located in membrane. WB:WBGene00013852 hhat-1 Predicted to enable palmitoyltransferase activity. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in chondrodysplasia-pseudohermaphroditism syndrome. Is an ortholog of human HHAT (hedgehog acyltransferase). WB:WBGene00013853 ZC116.1 Enriched in coelomocyte and pm8 based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including nicotinic acid; rotenone; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00013854 cyc-2.2 Predicted to enable electron transfer activity; heme binding activity; and metal ion binding activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen and mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; carcinoma (multiple); and thrombocytopenia. Is an ortholog of human CYCS (cytochrome c, somatic). WB:WBGene00013855 cubn-1 Predicted to enable calcium ion binding activity. Predicted to be involved in lipid metabolic process and protein transport. Predicted to be located in extracellular region. Expressed in tail. Human ortholog(s) of this gene implicated in coronary artery disease. Is an ortholog of human CUBN (cubilin). WB:WBGene00013856 ZC168.2 Acts upstream of or within ATF6-mediated unfolded protein response and PERK-mediated unfolded protein response. WB:WBGene00013857 orc-5 Predicted to enable DNA replication origin binding activity. Predicted to be involved in DNA replication initiation. Predicted to be located in nucleus. Predicted to be part of nuclear origin of replication recognition complex. Is an ortholog of human ORC5 (origin recognition complex subunit 5). WB:WBGene00013858 ssp-34 Enriched in ABalaapppa; ABalapaapa; GABAergic neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00013859 ZC247.1 Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in autophagy and cellular response to nitrogen starvation. Predicted to be located in autophagosome membrane and cytosol. WB:WBGene00013860 ZC247.2 Enriched in several structures, including GABAergic neurons; body wall muscle cell; enteric muscle; rectal muscle; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including aldicarb; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013861 ZC247.4 No description available WB:WBGene00013862 wdr-5.3 Predicted to enable dynein complex binding activity and microtubule plus-end binding activity. Predicted to be involved in several processes, including brain morphogenesis; microtubule-based process; and nuclear migration. Part of MLL3/4 complex. Is an ortholog of human WDR5 (WD repeat domain 5) and WDR5B (WD repeat domain 5B). WB:WBGene00013863 ZC302.3 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; stavudine; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00013865 ZC334.7 Predicted to enable protein-disulfide reductase activity. Predicted to be located in mitochondrion. WB:WBGene00013866 cbs-1 Enables cystathionine beta-synthase activity; cysteine synthase activity; and pyridoxal phosphate binding activity. Involved in sulfur compound biosynthetic process. Located in cytoplasm. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in several diseases, including homocystinuria; hyperhomocysteinemia; and neural tube defect. Is an ortholog of human CBS (cystathionine beta-synthase). WB:WBGene00013867 ZC373.2 Enriched in AVK; anterior spermatheca; dopaminergic neurons; excretory gland cell; and posterior spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including Heme; Ethanol; and rotenone based on microarray and RNA-seq studies. WB:WBGene00013868 ZC373.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00013869 mlck-1 Predicted to enable myosin light chain kinase activity. Predicted to be involved in phosphorylation. Expressed in anal sphincter muscle; hermaphrodite gonad; pharynx; and vulval cell. Is an ortholog of human MYLK4 (myosin light chain kinase family member 4). WB:WBGene00013870 ZC373.5 Predicted to enable methylthioribulose 1-phosphate dehydratase activity and zinc ion binding activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytoplasm. Expressed in tail. Is an ortholog of human APIP (APAF1 interacting protein). WB:WBGene00013871 gnrr-3 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in GABAergic neurons and tail. WB:WBGene00013872 ZC374.2 Enriched in intestine and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including methylmercuric chloride; rotenone; and sesamin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Fibronectin type III superfamily; Immunoglobulin-like fold; Fibronectin type III domain; and Fibronectin type III. WB:WBGene00013873 cest-2.3 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). WB:WBGene00013874 cest-2.2 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). WB:WBGene00013875 cest-2.1 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). WB:WBGene00013876 ceh-74 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Expressed in neurons and somatic nervous system. WB:WBGene00013877 ints-2 Predicted to be involved in snRNA 3'-end processing. Predicted to be part of integrator complex. Is an ortholog of human INTS2 (integrator complex subunit 2). WB:WBGene00013878 atfs-1 Enables DNA-binding transcription factor activity, RNA polymerase II-specific; enzyme binding activity; and mitochondrial transcription factor activity. Involved in several processes, including mitochondrial unfolded protein response; positive regulation of nematode larval development; and regulation of gene expression. Located in mitochondrial matrix and nucleus. Human ortholog(s) of this gene implicated in prostate carcinoma. Is an ortholog of human ATF4 (activating transcription factor 4). WB:WBGene00013879 ZC376.8 Predicted to be located in membrane. WB:WBGene00013880 mppb-1 Contributes to metalloendopeptidase activity. Involved in proteolysis. Part of mitochondrial processing peptidase complex. Human ortholog(s) of this gene implicated in Alzheimer's disease and multiple mitochondrial dysfunctions syndrome 6. Is an ortholog of human PMPCB (peptidase, mitochondrial processing subunit beta). WB:WBGene00013881 mans-4 Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in Rafiq syndrome. Is an ortholog of human MAN1B1 (mannosidase alpha class 1B member 1). WB:WBGene00013882 msa-1 Predicted to be located in membrane. WB:WBGene00013883 npr-13 Predicted to enable neuropeptide binding activity and neuropeptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection and plasma membrane. Human ortholog(s) of this gene implicated in hypertension; peripheral artery disease; and temporal lobe epilepsy. Is an ortholog of human PRLHR (prolactin releasing hormone receptor). WB:WBGene00013884 ZC412.3 Predicted to be located in extracellular region. WB:WBGene00013886 ZC412.5 Enriched in several structures, including AVG; RIM; command interneuron; germ line; and neuronal sheath cell based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5386 and Family of unknown function (DUF5386). WB:WBGene00013887 nspa-5 Enriched in amphid sheath cell; neurons; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; Ethanol; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00013888 nspa-3 Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00013889 ZC412.8 Is affected by several genes including daf-2; eat-2; and pmk-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013890 ZC412.9 Enriched in arcade cell; neurons; and pharyngeal-intestinal valve cell based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Acrylamide; Chlorpyrifos; and Diazinon based on microarray and RNA-seq studies. WB:WBGene00013891 ZC434.3 Enriched in several structures, including AFD; DD neuron; PLM; PVR; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including aldicarb; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00013892 ZC434.4 Predicted to be involved in rRNA processing and ribosomal small subunit assembly. Predicted to be part of CURI complex and UTP-C complex. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Is an ortholog of human RRP7A (ribosomal RNA processing 7 homolog A). WB:WBGene00013893 coa-6 Predicted to be involved in mitochondrial ATP synthesis coupled electron transport and respiratory chain complex IV assembly. Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex IV. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 54. Is an ortholog of human PRORP (protein only RNase P catalytic subunit). WB:WBGene00013894 ZC434.8 Predicted to enable kinase activity. Predicted to be involved in phosphocreatine biosynthetic process and phosphorylation. Is an ortholog of several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1B (creatine kinase, mitochondrial 1B). WB:WBGene00013895 ZC434.9 Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Is an ortholog of human CPA6 (carboxypeptidase A6). WB:WBGene00013896 ZC443.1 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. WB:WBGene00013897 ZC443.2 Enriched in several structures, including ABalaappppa; ABalapaappa; carbon dioxide sensory neurons; head neurons; and pharynx based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00013898 ZC443.3 Predicted to enable translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in several structures, including pharynx. WB:WBGene00013899 ZC443.4 Enriched in interfacial epithelial cell; neurons; pharyngeal muscle cell; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Sirolimus; antimycin; and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00013900 ugt-18 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00013901 ugt-16 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Expressed in intestine and pharynx. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1). WB:WBGene00013902 ZC455.1 Enriched in arcade cell; coelomocyte; pharyngeal muscle cell; pharyngeal-intestinal valve; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by fifteen chemicals including rotenone; D-glucopyranose; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013903 ugt-3 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00013904 ugt-6 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00013905 ugt-4 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00013906 ugt-5 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1); UGT3A2 (UDP glycosyltransferase family 3 member A2); and UGT8 (UDP glycosyltransferase 8). WB:WBGene00013907 sre-20 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00013908 srbc-43 Predicted to be located in membrane. WB:WBGene00013909 srbc-44 Predicted to be located in membrane. WB:WBGene00013910 srbc-45 Predicted to be located in membrane. WB:WBGene00013911 irld-60 Enriched in AFD; ASJ; and neurons based on tiling array; single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including eat-2; pgl-1; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Psoralens; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00013912 irld-19 Predicted to be located in membrane. WB:WBGene00013913 irld-61 Enriched in ABarpapaaa; ABplaaaaaa; ABplpaaapa; and ABprpaaapa based on single-cell RNA-seq studies. Is affected by several genes including alg-1; cyc-1; and etr-1 based on microarray and RNA-seq studies. Is affected by Progesterone based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00013914 lgc-37 Predicted to enable neurotransmitter receptor activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in neurons. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; autistic disorder; and epilepsy (multiple). Is an ortholog of human GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2). WB:WBGene00013915 irld-20 Predicted to be located in membrane. WB:WBGene00013916 ZC504.1 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00013917 cdk-11.2 Predicted to enable protein serine/threonine kinase activity. Involved in positive regulation of embryonic development. Located in cytoplasm and nucleus. Expressed in gonad; gonadal sheath cell; somatic cell; and somatic gonad. Is an ortholog of human CDK11A (cyclin dependent kinase 11A) and CDK11B (cyclin dependent kinase 11B). WB:WBGene00013918 C12C8.t6 No description available WB:WBGene00013919 ZC506.1 Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in endoplasmic reticulum. Expressed in several structures, including CAN; coelomocyte; distal tip cell; egg-laying apparatus; and tail. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Is an ortholog of human EDEM3 (ER degradation enhancing alpha-mannosidase like protein 3). WB:WBGene00013920 pssy-1 Predicted to enable L-serine-phosphatidylethanolamine phosphatidyltransferase activity. Predicted to be involved in phosphatidylserine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Lenz-Majewski hyperostotic dwarfism. Is an ortholog of human PTDSS1 (phosphatidylserine synthase 1). WB:WBGene00013921 best-22 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). WB:WBGene00013923 ghi-1 Predicted to enable lipid binding activity. WB:WBGene00013924 rad-23 Predicted to enable polyubiquitin modification-dependent protein binding activity; proteasome binding activity; and ubiquitin binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleoplasm. Expressed in dorsal nerve cord; head; neurons; ventral nerve cord; and vulva. Is an ortholog of human RAD23A (RAD23 homolog A, nucleotide excision repair protein). WB:WBGene00013925 coa-7 Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human COA7 (cytochrome c oxidase assembly factor 7). WB:WBGene00013926 nep-1 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Expressed in RIH and pharynx. Human ortholog(s) of this gene implicated in Alzheimer's disease; artery disease (multiple); congestive heart failure; and dilated cardiomyopathy. Is an ortholog of human ECE1 (endothelin converting enzyme 1). WB:WBGene00013927 clec-95 Enriched in LUA; male-specific anatomical entity; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by ten chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00013928 clec-94 Enriched in AVK based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00013929 clec-93 Enriched in AVK based on RNA-seq studies. Is affected by rsr-2 based on tiling array studies. Is affected by allantoin and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00013930 clec-96 Enriched in male based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00013931 clec-97 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including D-glucose; bisphenol S; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00013932 clec-98 Is affected by several genes including daf-2; eat-2; and nhr-49 based on tiling array; RNA-seq; and microarray studies. Is affected by fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00013933 clec-99 Enriched in NSM; RME; amphid sheath cell; germ line; and in male based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00013934 ZK131.11 Enriched in several structures, including ADE sheath cell; head ganglion; marginal cell; neurons; and pm7 based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including Cry5B; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013935 ZK218.1 Enriched in AVL; intestine; and pharyngeal-intestinal valve based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including let-60; rrf-3; and elt-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including aldicarb; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00013936 ZK218.2 No description available WB:WBGene00013937 ZK218.3 Enriched in g1AL; g1AR; and g1P based on single-cell RNA-seq studies. Is affected by several genes including nhr-49; lin-15B; and daf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Ag nanoparticles; resveratrol; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00013938 ZK218.4 Predicted to be located in membrane. WB:WBGene00013939 ZK218.5 Enriched in g1AL; g1AR; and g1P based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Zidovudine; Tunicamycin; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00013940 nhr-248 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00013941 ZK218.7 Is affected by several genes including daf-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by resveratrol and adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00013942 ZK218.8 Is affected by several genes including eat-2; cyc-1; and qui-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00013943 ZK218.11 Enriched in g1AL; g1AR; and muscle cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00013944 ZK228.1 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00013945 ZK228.2 No description available WB:WBGene00013946 ZK228.3 Enriched in intestine and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including diallyl trisulfide; Tunicamycin; and indole based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; YitH/HolE, acetyltransferase (GNAT) domain; and Acetyltransferase (GNAT) domain. WB:WBGene00013947 ZK228.4 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Involved in innate immune response. WB:WBGene00013948 C13B4.t1 No description available WB:WBGene00013949 ZK262.2 Predicted to be involved in lipid metabolic process. Expressed in neuronal sheath cell and pharynx. WB:WBGene00013950 txt-8 Predicted to enable hydrolase activity. Predicted to be involved in lipid catabolic process. Predicted to be located in extracellular region. WB:WBGene00013951 ZK262.4 Enriched in ABalpppapa; ABpraaaapa; amphid sheath cell; body wall muscle cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and aak-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00013952 ZK262.5 No description available WB:WBGene00013953 ZK262.8 Enriched in DA neuron; VA neuron; body wall muscle cell; germline precursor cell; and pharyngeal muscle cell based on tiling array studies. Is affected by several genes including skn-1; age-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Ag nanoparticles; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00013954 ZK262.9 Enriched in NSM based on tiling array studies. Is affected by several genes including skn-1; pgl-1; and hsp-6 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; paraquat; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00013955 kri-1 Involved in positive regulation of gene expression. Located in apical plasma membrane; apicolateral plasma membrane; and nucleus. Expressed in intestine and pharynx. Used to study cerebral cavernous malformation. Human ortholog(s) of this gene implicated in cerebral cavernous malformation 1. Is an ortholog of human KRIT1 (KRIT1 ankyrin repeat containing). WB:WBGene00013956 nsph-2 Expressed in sperm and spermatocyte. Is predicted to encode a protein with the following domain: Cytosolic motility protein. WB:WBGene00013957 sre-23 Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. Expressed in head and tail. WB:WBGene00013958 nol-16 Predicted to be involved in ribosomal large subunit biogenesis. Located in nucleolus. Is an ortholog of human NOP16 (NOP16 nucleolar protein). WB:WBGene00013959 ZK265.7 Enriched in several structures, including head mesodermal cell; marginal cell; neurons; pm6; and rectal gland cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00013960 cutl-8 Predicted to be located in membrane. WB:WBGene00013961 ZK285.2 Predicted to be located in membrane. WB:WBGene00013962 ZK287.1 Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines and zinc ion binding activity. Predicted to be located in nucleus. Expressed in tail. WB:WBGene00013963 sulp-8 Predicted to enable salt transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Located in basolateral plasma membrane. Expressed in excretory cell and intestine. Human ortholog(s) of this gene implicated in several diseases, including Pendred Syndrome; autosomal recessive nonsyndromic deafness 4; and bone disease (multiple). Is an ortholog of human SLC26A3 (solute carrier family 26 member 3) and SLC26A4 (solute carrier family 26 member 4). WB:WBGene00013964 nlp-73 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00013965 ZK287.4 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00013966 ztf-9 Enriched in germ line; head mesodermal cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Sirolimus; Rifampin; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type and Phosphorylation site. WB:WBGene00013967 ZK287.7 Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Is an ortholog of human RPUSD3 (RNA pseudouridine synthase D3) and RPUSD4 (RNA pseudouridine synthase D4). WB:WBGene00013968 ZK287.9 Predicted to be located in membrane. WB:WBGene00013969 tep-1 Predicted to enable endopeptidase inhibitor activity. Predicted to be located in extracellular space. Is an ortholog of human CD109 (CD109 molecule). WB:WBGene00013970 klu-1 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. WB:WBGene00013971 scl-19 Predicted to be located in extracellular space. Is an ortholog of several human genes including CRISPLD1 (cysteine rich secretory protein LCCL domain containing 1); GLIPR1 (GLI pathogenesis related 1); and PI15 (peptidase inhibitor 15). WB:WBGene00013972 scl-20 Predicted to be located in extracellular space. Is an ortholog of human GLIPR1 (GLI pathogenesis related 1) and R3HDML (R3H domain containing like). WB:WBGene00013973 asp-18 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human REN (renin). WB:WBGene00013974 npr-9 Predicted to enable G protein-coupled receptor activity. Involved in foraging behavior. Predicted to be located in plasma membrane. Expressed in AIBL and AIBR. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human GALR2 (galanin receptor 2). WB:WBGene00013975 ZK455.5 Predicted to enable transferase activity. Predicted to be located in membrane. WB:WBGene00013976 hizr-1 Enables DNA-binding transcription factor activity; cis-regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Involved in intracellular zinc ion homeostasis and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. WB:WBGene00013978 ZK507.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00013979 ZK507.3 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00013980 dos-1 Predicted to enable Notch binding activity. Predicted to be involved in positive regulation of Notch signaling pathway. Predicted to be located in extracellular space. WB:WBGene00013982 ZK512.1 Predicted to be located in membrane. WB:WBGene00013983 ZK512.2 Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be located in nucleolus. Expressed in head; intestine; and tail. Is an ortholog of human DDX55 (DEAD-box helicase 55). WB:WBGene00013984 ZK512.4 Predicted to enable 7S RNA binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in cytoplasm. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Expressed widely. Is an ortholog of human SRP9 (signal recognition particle 9). WB:WBGene00013985 sec-16A.1 Involved in endoplasmic reticulum to Golgi vesicle-mediated transport and protein localization to endoplasmic reticulum exit site. Located in endoplasmic reticulum exit site. Is an ortholog of human SEC16A (SEC16 homolog A, endoplasmic reticulum export factor). WB:WBGene00013986 ZK512.7 Enriched in AUA; DVC; and sensory neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-six chemicals including Ethanol; rotenone; and Tunicamycin based on RNA-seq; microarray; and proteomic studies. WB:WBGene00013987 ZK512.8 Enriched in several structures, including NSM; arcade cell; germ line; pharyngeal-intestinal valve cell; and sperm based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5386 and Family of unknown function (DUF5386). WB:WBGene00013988 ZK512.10 Enriched in CEPshDL; CEPshDR; CEPshVL; CEPshVR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; D-glucose; and allantoin based on microarray and RNA-seq studies. WB:WBGene00013989 ZK512.11 Predicted to be located in membrane. WB:WBGene00013993 C15C6.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00013994 ZK524.4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Is an ortholog of human SNRK (SNF related kinase). WB:WBGene00013995 mboa-5 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and npr-1 based on RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00013996 ZK550.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00013997 eelo-2 Predicted to enable metal ion binding activity and metalloendopeptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human THOP1 (thimet oligopeptidase 1). WB:WBGene00013998 gtf-2E1 Predicted to enable RNA polymerase II complex binding activity. Involved in transcription initiation at RNA polymerase II promoter. Part of transcription factor TFIIE complex. Is an ortholog of human GTF2E1 (general transcription factor IIE subunit 1). WB:WBGene00013999 phyh-1 Predicted to enable phytanoyl-CoA dioxygenase activity. Predicted to be involved in fatty acid alpha-oxidation. Expressed in nerve ring. Human ortholog(s) of this gene implicated in Refsum disease; Zellweger syndrome; and orofacial cleft. Is an ortholog of human PHYH (phytanoyl-CoA 2-hydroxylase). WB:WBGene00014000 ZK550.6 Predicted to enable phytanoyl-CoA dioxygenase activity. Predicted to be involved in fatty acid alpha-oxidation. Expressed in intestine. Human ortholog(s) of this gene implicated in Refsum disease; Zellweger syndrome; and orofacial cleft. Is an ortholog of human PHYH (phytanoyl-CoA 2-hydroxylase). WB:WBGene00014001 pyk-2 Predicted to enable pyruvate kinase activity. Predicted to be involved in glycolytic process. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Expressed in intestine. Is an ortholog of human PKM (pyruvate kinase M1/2). WB:WBGene00014002 ZK593.2 Enriched in Z1; Z4; body wall muscle cell; dopaminergic neurons; and muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; Tunicamycin; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00014003 ZK593.3 Predicted to be located in membrane. WB:WBGene00014004 fic-1 Enables protein adenylyltransferase activity. Involved in defense response to Gram-negative bacterium. Located in endoplasmic reticulum and nuclear envelope. Expressed widely. Is an ortholog of human FICD (FIC domain protein adenylyltransferase). WB:WBGene00014005 ZK593.9 Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Sodium Chloride; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00014006 srlf-30 Expressed in g1AL; g1AR; g1P; g2L; and g2R. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00014007 ZK596.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00014008 ZK596.3 Predicted to be located in membrane. WB:WBGene00014009 lips-6 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. Expressed in intestine; tail; and vulva. WB:WBGene00014011 ZK632.2 Predicted to enable mRNA binding activity. Is an ortholog of human SLC4A1AP (solute carrier family 4 member 1 adaptor protein). WB:WBGene00014012 riok-3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in cytosol. Predicted to be part of preribosome, small subunit precursor. Expressed in intestine. Is an ortholog of human RIOK3 (RIO kinase 3). WB:WBGene00014013 ZK632.4 Predicted to enable mannose-6-phosphate isomerase activity. Predicted to be involved in GDP-mannose biosynthetic process. Predicted to be located in cytosol. Expressed in amphid neurons; head neurons; hypodermis; intestine; and nervous system. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ib. Is an ortholog of human MPI (mannose phosphate isomerase). WB:WBGene00014014 gtap-2 Predicted to enable gamma-tubulin binding activity. WB:WBGene00014015 panl-3 Predicted to enable poly(A) binding activity. Involved in reproduction. Predicted to be located in P-body. Predicted to be part of PAN complex. Is an ortholog of human PAN3 (poly(A) specific ribonuclease subunit PAN3). WB:WBGene00014016 ZK632.9 Enriched in M cell; germline precursor cell; intestine; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by nine chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Nuclear protein 1-like; DNA-binding nuclear phosphoprotein p8; and Phosphorylation site. WB:WBGene00014017 ZK632.10 Predicted to be located in membrane. WB:WBGene00014018 ZK632.11 Predicted to enable RNA binding activity. Predicted to be involved in ncRNA processing. Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human ZCCHC8 (zinc finger CCHC-type containing 8). WB:WBGene00014019 ZK632.12 Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in endosome organization and endosome to lysosome transport. Predicted to be located in early endosome. Expressed in intestine; pharynx; and reproductive system. Is an ortholog of human PLEKHF2 (pleckstrin homology and FYVE domain containing 2). WB:WBGene00014020 ZK632.14 Predicted to enable RNA binding activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be part of ribonuclease MRP complex. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human RPP25 (ribonuclease P and MRP subunit p25) and RPP25L (ribonuclease P/MRP subunit p25 like). WB:WBGene00014021 svop-1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SVOP (SV2 related protein). WB:WBGene00014022 famh-136 Located in striated muscle dense body. Is an ortholog of human FAM136A (family with sequence similarity 136 member A). WB:WBGene00014023 lnkn-1 Predicted to be involved in cell adhesion. Located in apical plasma membrane and lateral plasma membrane. Expressed in several structures, including excretory cell; germ cell; gonad; hypodermis; and nervous system. Is an ortholog of human ITFG1 (integrin alpha FG-GAP repeat containing 1). WB:WBGene00014024 ZK637.4 Enriched in intestine; neurons; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including daf-12; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including aldicarb; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00014025 asna-1 Enables ATP hydrolysis activity. Involved in detoxification of arsenic-containing substance and positive regulation of insulin secretion. Located in axon and neuronal cell body. Expressed in several structures, including excretory cell; intestine; nervous system; pharynx; and reproductive system. Used to study cancer. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Is an ortholog of human GET3 (guided entry of tail-anchored proteins factor 3, ATPase). WB:WBGene00014026 C17D12.t1 No description available WB:WBGene00014027 tpk-1 Predicted to enable thiamine diphosphokinase activity. Predicted to be involved in thiamine diphosphate biosynthetic process. Expressed in body wall musculature and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in inherited metabolic disorder. Is an ortholog of human TPK1 (thiamin pyrophosphokinase 1). WB:WBGene00014028 trxr-2 Enables thioredoxin-disulfide reductase (NADP) activity. Involved in obsolete oxidation-reduction process. Located in mitochondrion. Expressed in intestine; muscle cell; nervous system; and vulva. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in familial glucocorticoid deficiency. Is an ortholog of human TXNRD2 (thioredoxin reductase 2). WB:WBGene00014029 ZK637.12 Enriched in germ line and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; D-glucose; and allantoin based on microarray and RNA-seq studies. WB:WBGene00014030 glb-1 Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Predicted to be located in cytoplasm. Expressed in VC neuron; germ line; head muscle; head neurons; and tail neurons. WB:WBGene00014031 ZK637.14 Predicted to enable zinc ion binding activity. WB:WBGene00014032 ZK637.15 Enriched in AFD and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including Rifampin; Sirolimus; and antimycin based on RNA-seq and microarray studies. WB:WBGene00014033 arrd-15 Predicted to be involved in protein transport. Located in striated muscle dense body. Expressed in ganglia and vm1. WB:WBGene00014034 ZK643.2 Predicted to enable dCMP deaminase activity and metal ion binding activity. Predicted to be involved in nucleotide biosynthetic process. Predicted to be located in cytoplasm. Expressed in hypodermis. Is an ortholog of human DCTD (dCMP deaminase). WB:WBGene00014035 seb-2 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in M.vlpaaapp; M.vlpaapaa; M.vrpaaapp; M.vrpaapaa; and head muscle. Human ortholog(s) of this gene implicated in achalasia; inflammatory bowel disease (multiple); and isolated growth hormone deficiency. Is an ortholog of several human genes including ADCYAP1R1 (ADCYAP receptor type I); GHRHR (growth hormone releasing hormone receptor); and GLP1R (glucagon like peptide 1 receptor). WB:WBGene00014036 ZK643.5 Expressed in head ganglion; lateral ganglion; tail neurons; ventral ganglion; and ventral nerve cord. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00014037 ZK643.6 Enriched in ABalapapapa; ABalapppapa; ABarpaaa; ABplpaaappa; and ABprpaaappa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-18; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Atrazine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00014039 ZK662.2 Enriched in anterior hypodermis; arcade cell; cholinergic neurons; pharyngeal-intestinal valve; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-eight chemicals including 1-methylnicotinamide; nicotinic acid; and rotenone based on RNA-seq and microarray studies. WB:WBGene00014040 ZK662.5 Predicted to be involved in negative regulation of vulval development. WB:WBGene00014041 ZK666.1 Is affected by several genes including daf-2; rrf-3; and mex-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00014042 ZK666.2 Enriched in amphid sheath cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; D-glucose; and Tamoxifen based on microarray and RNA-seq studies. WB:WBGene00014043 clec-58 Enriched in NSM based on tiling array studies. Is affected by several genes including eat-2; pmk-1; and nhr-49 based on RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; C-type lectin-like; von Willebrand factor A-like domain superfamily; C-type lectin-like/link domain superfamily; Lectin C-type domain; and C-type lectin fold. WB:WBGene00014044 ZK666.4 Is affected by several genes including daf-2; let-60; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including hydrogen sulfide; Tunicamycin; and cadmium based on microarray studies. WB:WBGene00014045 clec-59 Is affected by several genes including daf-2; lin-4; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; C-type lectin-like; von Willebrand factor A-like domain superfamily; C-type lectin-like/link domain superfamily; and C-type lectin fold. WB:WBGene00014046 clec-60 Involved in defense response to Gram-positive bacterium. Expressed in intestine. WB:WBGene00014047 clec-61 Involved in defense response to Gram-positive bacterium. WB:WBGene00014048 ZK666.8 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00014049 ZK666.11 Is affected by several genes including nhr-49; csr-1; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by methylmercuric chloride and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00014050 ZK666.12 Predicted to be located in membrane. WB:WBGene00014051 spv-1 Enables GTPase activator activity. Involved in several processes, including cell-cell junction assembly; negative regulation of smooth muscle contraction; and regulation of protein localization. Located in apical plasma membrane and cell-cell junction. Expressed in head neurons; hypodermis; spermatheca; spermathecal cell; and tail neurons. Is an ortholog of human GMIP (GEM interacting protein). WB:WBGene00014052 ZK669.2 Predicted to enable oxidoreductase activity. Is an ortholog of human IFI30 (IFI30 lysosomal thiol reductase). WB:WBGene00014053 ZK669.3 Predicted to enable oxidoreductase activity. Predicted to be located in extracellular region. Is an ortholog of human IFI30 (IFI30 lysosomal thiol reductase). WB:WBGene00014054 dbt-1 Predicted to enable acetyltransferase activity and lipoic acid binding activity. Involved in positive regulation of fatty acid biosynthetic process and positive regulation of multicellular organismal process. Located in cilium; cytosol; and neuron projection. Expressed in several structures, including body wall musculature; head neurons; hypodermis; and intestine. Human ortholog(s) of this gene implicated in maple syrup urine disease. Is an ortholog of human DBT (dihydrolipoamide branched chain transacylase E2). WB:WBGene00014055 ZK669.5 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Rap protein signal transduction; cellular response to cAMP; and negative regulation of synaptic vesicle exocytosis. Predicted to be located in plasma membrane. WB:WBGene00014057 ZK673.1 Predicted to be located in membrane. WB:WBGene00014058 ZK673.2 Predicted to enable adenylate kinase activity and nucleoside triphosphate adenylate kinase activity. Predicted to be involved in AMP metabolic process and nucleoside triphosphate biosynthetic process. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in chronic lymphocytic leukemia and hepatocellular carcinoma. Is an ortholog of human AK3 (adenylate kinase 3) and AK4 (adenylate kinase 4). WB:WBGene00014060 ZK673.4 Predicted to enable metal ion binding activity. WB:WBGene00014061 ZK673.5 Enriched in arcade cell; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including hydrogen sulfide; Rifampin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00014062 ZK673.6 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-60 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00014063 clec-143 Enriched in intestine and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nineteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; C-type lectin-like; von Willebrand factor A-like domain superfamily; C-type lectin-like/link domain superfamily; Lectin C-type domain; and C-type lectin fold. WB:WBGene00014064 sdz-37 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; Rifampin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00014065 ZK673.11 Predicted to be located in membrane. Expressed in PVCL; PVCR; RID; and cholinergic neurons. WB:WBGene00014066 rev-1 Predicted to enable DNA-directed DNA polymerase activity and deoxycytidyl transferase activity. Predicted to be involved in error-free translesion synthesis and error-prone translesion synthesis. Predicted to be located in nucleus. Expressed in intestine; neurons; and vm1. Is an ortholog of human REV1 (REV1 DNA directed polymerase). WB:WBGene00014067 ZK675.4 Enriched in intestine; rectal epithelial cell; rectal gland cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; age-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; Mercuric Chloride; and sesamin based on microarray and RNA-seq studies. WB:WBGene00014068 nhr-255 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00014069 ZK678.3 Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00014070 srxa-9 Predicted to be located in membrane. WB:WBGene00014073 ZK757.1 Predicted to be located in membrane. Expressed in AIYL and AIYR. WB:WBGene00014074 ZK757.2 Predicted to enable protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00014075 dhhc-4 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane and synaptic vesicle maturation. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Expressed in several structures, including enteric muscle; gonad; nervous system; pharyngeal-intestinal valve; and rectum. Is an ortholog of human ZDHHC15 (zinc finger DHHC-type palmitoyltransferase 15); ZDHHC2 (zinc finger DHHC-type palmitoyltransferase 2); and ZDHHC20 (zinc finger DHHC-type palmitoyltransferase 20). WB:WBGene00014076 ZK792.1 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in membrane. Expressed in intestine; nervous system; and rectal epithelium. Is an ortholog of human PXYLP1 (2-phosphoxylose phosphatase 1). WB:WBGene00014077 ZK792.4 Expressed in several structures, including amphid socket cell; head; intestine; pharynx; and rectal gland cell. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 36. Is predicted to encode a protein with the following domains: Ankyrin repeats (3 copies); Ankyrin repeat-containing domain superfamily; Ankyrin repeat; and Ankyrin repeats (many copies). Is an ortholog of human ANKRD16 (ankyrin repeat domain 16); ESPN (espin); and ESPNL (espin like). WB:WBGene00014078 ZK792.5 Predicted to enable RNA binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in nucleolus. Predicted to be part of 90S preribosome and preribosome, small subunit precursor. Is an ortholog of human NOP9 (NOP9 nucleolar protein). WB:WBGene00014079 ZK792.7 Predicted to be located in endoplasmic reticulum. Expressed in body wall musculature; head neurons; pharyngeal muscle cell; and tail neurons. WB:WBGene00014080 atg-4.2 Enables cysteine-type endopeptidase activity. Predicted to be involved in autophagy; protein transport; and proteolysis. Predicted to be located in cytoplasm. Expressed in embryonic cell; gonad; and oocyte. Is an ortholog of human ATG4D (autophagy related 4D cysteine peptidase). WB:WBGene00014081 ipmk-1 Predicted to enable inositol tetrakisphosphate kinase activity and inositol-1,4,5-trisphosphate 3-kinase activity. Predicted to be involved in inositol phosphate biosynthetic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human IPMK (inositol polyphosphate multikinase). WB:WBGene00014082 ZK795.2 Predicted to be located in membrane. Expressed in germ line. WB:WBGene00014083 ZK795.3 Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of Mpp10 complex and small-subunit processome. Expressed in several structures, including P6.paa; P6.pap; enteric muscle; excretory cell; and reproductive system. Is an ortholog of human IMP4 (IMP U3 small nucleolar ribonucleoprotein 4). WB:WBGene00014084 snb-7 Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in vesicle fusion. Predicted to be located in plasma membrane. Predicted to be part of SNARE complex. Is an ortholog of human VAMP7 (vesicle associated membrane protein 7). WB:WBGene00014085 ZK809.1 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00014086 ndub-6 Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in membrane. Predicted to be part of mitochondrial respiratory chain complex I. WB:WBGene00014087 ZK809.5 Predicted to be located in motile cilium. WB:WBGene00014088 ZK809.8 Predicted to be located in membrane. WB:WBGene00014089 ZK822.1 Enriched in intestine; muscle cell; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00014090 srlf-31 Enriched in several structures, including ABarpaapap; accessory cell; g2; germ line; and neurons based on tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00014091 srlf-32 Enriched in AFD; AMshL; AMshR; PLM; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including aldicarb; bisphenol A; and procyanidin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00014092 slc-5A12 Predicted to enable symporter activity. Predicted to be involved in sodium ion transport. Predicted to be located in membrane. Expressed in several structures, including intestine; nervous system; non-striated muscle; pharynx; and rectal gland cell. Human ortholog(s) of this gene implicated in thyroid dyshormonogenesis 1. Is an ortholog of human SLC5A12 (solute carrier family 5 member 12) and SLC5A8 (solute carrier family 5 member 8). WB:WBGene00014093 ZK829.1 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and aak-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Cry5B; Doxycycline; and Colistin based on microarray and proteomic studies. Human HSD17B14 enables estradiol 17-beta-dehydrogenase [NAD(P)] activity; identical protein binding activity; and testosterone 17-beta-dehydrogenase (NADP+) activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and Enoyl-(Acyl carrier protein) reductase. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00014094 ZK829.3 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00014095 gdh-1 Predicted to enable glutamate dehydrogenase (NAD+) activity. Predicted to be involved in glutamate catabolic process. Predicted to be located in mitochondrion. Expressed in head; intestine; pharynx; rectal gland cell; and tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; glucose metabolism disease (multiple); and late onset Parkinson's disease. Is an ortholog of human GLUD1 (glutamate dehydrogenase 1). WB:WBGene00014096 ZK829.7 Predicted to enable alcohol dehydrogenase (NADP+) activity. Predicted to be involved in alcohol metabolic process. Expressed in several structures, including anal depressor muscle; egg-laying apparatus; intestine; nervous system; and rectal epithelium. WB:WBGene00014097 ZK829.9 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00014098 ogdh-2 Predicted to enable oxoglutarate dehydrogenase (succinyl-transferring) activity and thiamine pyrophosphate binding activity. Predicted to be involved in glycolytic process and tricarboxylic acid cycle. Predicted to be located in mitochondrion. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth disease axonal type 2Q. Is an ortholog of human DHTKD1 (dehydrogenase E1 and transketolase domain containing 1). WB:WBGene00014099 ZK836.3 Predicted to be located in membrane. WB:WBGene00014100 ZK849.1 Predicted to be located in Golgi apparatus. WB:WBGene00014101 gopc-1 Enables identical protein binding activity. Predicted to be involved in negative regulation of protein localization to cell surface. Predicted to be located in Golgi apparatus; membrane; and trans-Golgi network transport vesicle. Is an ortholog of human GOPC (golgi associated PDZ and coiled-coil motif containing). WB:WBGene00014102 best-25 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. WB:WBGene00014103 best-26 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. WB:WBGene00014104 ZK849.6 Predicted to be located in membrane. WB:WBGene00014105 ZK856.4 Enriched in ABplppppap; ABprppppap; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; fbf-1; and hpl-2 based on RNA-seq and microarray studies. Is affected by resveratrol and nitroguanidine based on microarray studies. WB:WBGene00014106 ZK856.5 Predicted to enable phosphoric diester hydrolase activity. Predicted to be located in extracellular space. Is an ortholog of human SMPDL3B (sphingomyelin phosphodiesterase acid like 3B). WB:WBGene00014107 ZK856.6 Enriched in neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; mex-3; and mex-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cystine-knot cytokine. WB:WBGene00014108 ZK856.7 Enriched in M cell; accessory cell; intestine; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by fourteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq; microarray; and proteomic studies. WB:WBGene00014109 chpf-1 Predicted to enable calcium ion binding activity. Predicted to be located in plasma membrane. Expressed in head; intestine; tail; and in male. Human ortholog(s) of this gene implicated in spastic ataxia. Is an ortholog of human CHP1 (calcineurin like EF-hand protein 1). WB:WBGene00014111 rpc-25 Predicted to be involved in transcription initiation at RNA polymerase III promoter. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is an ortholog of human POLR3H (RNA polymerase III subunit H). WB:WBGene00014112 ZK856.11 Predicted to enable RNA binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Located in nucleus. Is an ortholog of human EIF1AD (eukaryotic translation initiation factor 1A domain containing). WB:WBGene00014113 hpo-40 Located in mutator focus. Expressed in germ cell. WB:WBGene00014114 tftc-3 Predicted to be involved in transcription by RNA polymerase III. Predicted to be part of transcription factor TFIIIC complex. Is an ortholog of human GTF3C3 (general transcription factor IIIC subunit 3). WB:WBGene00014115 gld-4 Enables poly(A) RNA polymerase activity. Involved in mRNA polyadenylation. Located in P granule. Part of polysome. Expressed in Z2; Z3; and germ line. Is an ortholog of human TENT4A (terminal nucleotidyltransferase 4A) and TENT4B (terminal nucleotidyltransferase 4B). WB:WBGene00014116 ZK858.2 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00014117 clec-91 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Expressed in germ line. Is an ortholog of human CLEC2L (C-type lectin domain family 2 member L); KLRB1 (killer cell lectin like receptor B1); and KLRG1 (killer cell lectin like receptor G1). WB:WBGene00014118 ZK858.5 Predicted to be located in membrane. Is an ortholog of human DNAJC22 (DnaJ heat shock protein family (Hsp40) member C22). WB:WBGene00014119 ZK858.6 Predicted to be involved in protein localization to membrane. Predicted to be located in membrane. Expressed in intestine. Is an ortholog of human TM9SF4 (transmembrane 9 superfamily member 4). WB:WBGene00014120 trmt-6 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to be located in nucleus. Predicted to be part of tRNA (m1A) methyltransferase complex. Is an ortholog of human TRMT6 (tRNA methyltransferase 6 non-catalytic subunit). WB:WBGene00014121 ZK858.8 Enriched in AVK; Y cell; amphid sheath cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00014122 ZK863.1 Predicted to be located in membrane. WB:WBGene00014123 elpc-3 Predicted to enable phosphorylase kinase regulator activity. Involved in several processes, including gamete generation; gene expression; and olfactory learning. Predicted to be located in cytoplasm and nucleus. Predicted to be part of elongator holoenzyme complex. Expressed in CAN; HSN; amphid neurons; pharynx; and vulva. Used to study Riley-Day syndrome. Is an ortholog of human ELP3 (elongator acetyltransferase complex subunit 3). WB:WBGene00014124 usip-1 Enables RNA uridylyltransferase activity. Involved in U6 snRNA 3'-end processing. Located in nucleoplasm. Human ortholog(s) of this gene implicated in spastic ataxia 4. Is an ortholog of human MTPAP (mitochondrial poly(A) polymerase). WB:WBGene00014125 ZK863.8 Predicted to be located in membrane. WB:WBGene00014126 C17D12.t2 No description available WB:WBGene00014127 ZK892.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SVOPL (SVOP like). WB:WBGene00014128 ZK892.4 Predicted to enable alpha-methylacyl-CoA racemase activity. Predicted to be involved in bile acid metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including alpha-methylacyl-CoA racemase deficiency; congenital bile acid synthesis defect 4; and urinary system cancer (multiple). Is an ortholog of human AMACR (alpha-methylacyl-CoA racemase). WB:WBGene00014129 ZK892.5 Predicted to be located in membrane. WB:WBGene00014130 ZK892.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014131 sdz-38 Expressed in several structures, including MSaa; MSap; MSp; MSpa; and MSpp. WB:WBGene00014132 ZK896.1 Enriched in cephalic sheath cell; g2; intestine; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including methylmercury hydroxide; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00014134 ZK896.3 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00014135 ZK896.4 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including methylmercuric chloride; D-glucopyranose; and sodium arsenite based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily and CUB-like domain. WB:WBGene00014136 ZK896.5 Enriched in AFD; anterior ganglion; head mesodermal cell; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; microarray; and proteomic studies. Is affected by twenty-two chemicals including methylmercuric chloride; Tunicamycin; and D-glucopyranose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00014137 clec-187 Involved in innate immune response. WB:WBGene00014138 clec-186 Involved in innate immune response. WB:WBGene00014139 nstp-5 Predicted to enable UDP-galactose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport and carbohydrate transport. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIm. Is an ortholog of human SLC35A2 (solute carrier family 35 member A2). WB:WBGene00014140 ZK899.1 Enriched in several structures, including intestine; muscle cell; neurons; rectal epithelial cell; and rectum based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including stavudine; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00014141 ZK899.2 Predicted to be located in membrane. Expressed in buccal cavity and rectum. WB:WBGene00014142 ZK899.3 Enriched in several structures, including ABplpapppa; ABplppppaa; ABprppppaa; marginal cell; and rectal epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including age-1; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including metformin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00014143 ZK899.5 Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nine chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00014144 ZK899.6 Enriched in several structures, including ABplapppapp; ABprapppapp; BAG; NSM; and XXX cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00014145 ZK899.7 Enriched in neurons and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on microarray and RNA-seq studies. Is affected by Rifampin; allantoin; and fluoranthene based on RNA-seq and microarray studies. WB:WBGene00014147 C17D12.t3 No description available WB:WBGene00014148 ZK909.3 Predicted to enable guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity. Is an ortholog of human HDDC3 (HD domain containing 3). WB:WBGene00014149 fbxb-70 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalaappppa; ABalapaappa; and ciliated neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including aldicarb; 1-methylnicotinamide; and bisphenol S based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00014150 ZK909.6 Enriched in several structures, including ABalaaaarl; head mesodermal cell; intestinal muscle; neurons; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00014151 vps-15 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in autophagy and vacuolar transport. Predicted to be located in late endosome and nucleus-vacuole junction. Predicted to be part of phosphatidylinositol 3-kinase complex, class III, type I and phosphatidylinositol 3-kinase complex, class III, type II. Is an ortholog of human PIK3R4 (phosphoinositide-3-kinase regulatory subunit 4). WB:WBGene00014152 ZK930.2 Predicted to be involved in positive regulation of neuron differentiation. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Miles-Carpenter syndrome. Is an ortholog of human ZC4H2 (zinc finger C4H2-type containing). WB:WBGene00014153 vab-23 Involved in several processes, including embryonic body morphogenesis; epidermis morphogenesis; and vulval development. Located in nuclear speck. Expressed in several structures, including hermaphrodite somatic gonadal cell; ventral uterine precursor; vulval cell; vulval muscle; and vulval precursor cell. Human ortholog(s) of this gene implicated in Miles-Carpenter syndrome. Is an ortholog of human ZC4H2 (zinc finger C4H2-type containing). WB:WBGene00014154 ZK930.4 Enriched in several structures, including AIA; PVT; interfacial epithelial cell; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00014155 ZK930.5 Enriched in several structures, including ABplapaaap; ABprapaaap; Z1.p; Z4.a; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; pmk-1; and npr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and antimycin based on RNA-seq and microarray studies. WB:WBGene00014156 ZK930.6 Predicted to enable ATP-dependent peptidase activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00014157 ZK930.7 Enriched in male based on RNA-seq studies. Is affected by several genes including let-60; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Rifampin; and antimycin based on microarray and RNA-seq studies. WB:WBGene00014158 ZK938.1 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00014159 arrd-4 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Expressed in ciliated neurons. Is an ortholog of human ARRDC5 (arrestin domain containing 5). WB:WBGene00014160 ZK938.3 Predicted to enable gluconokinase activity. Predicted to be involved in D-gluconate catabolic process. WB:WBGene00014161 arrd-5 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC5 (arrestin domain containing 5). WB:WBGene00014162 chil-9 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00014163 rnh-1.2 Predicted to enable RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer. WB:WBGene00014164 lact-2 Predicted to be located in membrane. WB:WBGene00014165 puf-12 Predicted to enable mRNA binding activity. Predicted to be involved in regulation of translation. Predicted to be located in nucleolus. Is an ortholog of human PUM3 (pumilio RNA binding family member 3). WB:WBGene00014166 ZK945.4 Predicted to enable zinc ion binding activity. WB:WBGene00014168 ZK945.6 Enriched in amphid sheath cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00014169 ZK945.7 Enriched in DA neuron; VA neuron; sperm; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-nine chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00014170 ZK945.8 Predicted to enable protein phosphatase 1 binding activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be located in nucleus. Is an ortholog of human PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11). WB:WBGene00014171 nep-26 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00014172 clpp-1 Enables serine-type endopeptidase activity. Involved in mitochondrial unfolded protein response and proteolysis. Located in mitochondrial matrix. Expressed in intestine. Human ortholog(s) of this gene implicated in Perrault syndrome. Is an ortholog of human CLPP (caseinolytic mitochondrial matrix peptidase proteolytic subunit). WB:WBGene00014173 srlf-34 Involved in response to gamma radiation. WB:WBGene00014174 ZK970.8 Predicted to enable guanyl-nucleotide exchange factor activity and zinc ion binding activity. Predicted to be involved in post-Golgi vesicle-mediated transport. Predicted to be located in cytosol and membrane. Is an ortholog of human RABIF (RAB interacting factor). WB:WBGene00014175 ZK971.1 Enriched in coelomocyte; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including Tunicamycin; stavudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00014176 ZK1010.2 Predicted to be involved in positive regulation of mitochondrial translation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 11. Is an ortholog of human RMND1 (required for meiotic nuclear division 1 homolog). WB:WBGene00014177 frg-1 Enables actin filament binding activity and protein homodimerization activity. Involved in actin filament bundle assembly. Located in nucleolus and striated muscle dense body. Used to study facioscapulohumeral muscular dystrophy. Is an ortholog of human FRG1 (FSHD region gene 1). WB:WBGene00014178 ZK1010.4 Enriched in ADE sheath cell; anterior ganglion; anterior hypodermis; arc ant V; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00014179 ZK1010.5 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-six chemicals including aldicarb; hydrogen sulfide; and Ethanol based on microarray and RNA-seq studies. WB:WBGene00014180 ZK1010.6 Enriched in NSM and RID based on tiling array and RNA-seq studies. Is affected by several genes including csr-1; mex-1; and spn-4 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including metformin; Sirolimus; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00014181 ZK1010.8 Predicted to be located in membrane. WB:WBGene00014182 ZK1025.2 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00014183 ZK1025.3 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00014184 ZK1025.4 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00014185 ZK1025.5 Is affected by several genes including sir-2.1; clk-1; and daf-18 based on microarray and RNA-seq studies. Is affected by Ethanol; methylmercury hydroxide; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00014186 nhr-244 Predicted to be located in nucleus. WB:WBGene00014188 ZK1025.8 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00014189 nhr-245 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. WB:WBGene00014190 irld-62 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; prg-1; and unc-75 based on tiling array; RNA-seq; and microarray studies. Is affected by Acrylamide; Chlorpyrifos; and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00014191 srt-22 Predicted to be located in membrane. WB:WBGene00014192 nhr-246 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Expressed in hypodermis and intestine. WB:WBGene00014193 nhr-247 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Is an ortholog of human NR1H2 (nuclear receptor subfamily 1 group H member 2). WB:WBGene00014194 ZK1037.6 Predicted to be located in membrane. WB:WBGene00014195 srz-10 Predicted to be located in membrane. WB:WBGene00014196 ZK1053.1 Predicted to be located in membrane. WB:WBGene00014197 ZK1053.2 Predicted to be located in membrane. WB:WBGene00014198 ZK1053.3 Predicted to be involved in autophagy. WB:WBGene00014199 ZK1053.4 Predicted to be involved in autophagy. Located in cytoplasm. WB:WBGene00014200 scrm-2 Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be located in plasma membrane. Is an ortholog of several human genes including PLSCR2 (phospholipid scramblase 2); PLSCR3 (phospholipid scramblase 3); and PLSCR4 (phospholipid scramblase 4). WB:WBGene00014201 ZK1053.6 Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. WB:WBGene00014202 mmcm-1 Enables methylmalonyl-CoA mutase activity. Involved in amino acid metabolic process and fatty acid metabolic process. Located in mitochondrion. Used to study methylmalonic acidemia. Human ortholog(s) of this gene implicated in methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency. Is an ortholog of human MMUT (methylmalonyl-CoA mutase). WB:WBGene00014203 ZK1058.3 Predicted to enable UDP-glucose:hexose-1-phosphate uridylyltransferase activity. Predicted to be involved in galactose catabolic process via UDP-galactose. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in classic galactosemia. Is an ortholog of human GALT (galactose-1-phosphate uridylyltransferase). WB:WBGene00014204 ccdc-47 Predicted to enable calcium ion binding activity. Predicted to be involved in endoplasmic reticulum calcium ion homeostasis. Predicted to be located in rough endoplasmic reticulum membrane. Expressed in tail. Is an ortholog of human CCDC47 (coiled-coil domain containing 47). WB:WBGene00014205 metl-6 Predicted to enable tRNA (cytosine-3-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Is an ortholog of human METTL6 (methyltransferase 6, tRNA N3-cytidine). WB:WBGene00014206 nit-1 Predicted to enable nitrilase activity. Predicted to be involved in nitrogen compound metabolic process. Expressed in several structures, including E; Ea; Ep; MSaa; and MSpa. WB:WBGene00014207 ZK1058.9 Enriched in germ line and muscle cell based on tiling array; proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including methylmercuric chloride; rotenone; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00014208 znfx-1 Predicted to enable RNA binding activity. Predicted to be involved in regulatory ncRNA-mediated heterochromatin formation. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be part of nuclear RNA-directed RNA polymerase complex. Expressed in Psub1; Psub2; Psub3; Psub4; and germ cell. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human ZNFX1 (zinc finger NFX1-type containing 1). WB:WBGene00014209 ZK1067.3 Enriched in several structures, including AFD; germ line; mechanosensory neurons; rectal epithelial cell; and rectum based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; sir-2.1; and sek-1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by nine chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00014210 ZK1067.4 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in dystonia. Is an ortholog of human TMEM151A (transmembrane protein 151A) and TMEM151B (transmembrane protein 151B). WB:WBGene00014213 ZK1073.1 Predicted to be involved in signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4D and glioblastoma. Is an ortholog of human NDRG1 (N-myc downstream regulated 1); NDRG2 (NDRG family member 2); and NDRG4 (NDRG family member 4). WB:WBGene00014214 ZK1073.2 Predicted to be located in lysosomal membrane. WB:WBGene00014215 obr-3 Predicted to enable cholesterol binding activity and sterol transporter activity. Involved in regulation of growth and transforming growth factor beta receptor signaling pathway. Predicted to be located in cytosol; intracellular membrane-bounded organelle; and membrane. Expressed in hypodermis; neurons; and pharyngeal muscle cell. Is an ortholog of human OSBPL5 (oxysterol binding protein like 5) and OSBPL8 (oxysterol binding protein like 8). WB:WBGene00014216 ZK1086.2 Predicted to be located in membrane. WB:WBGene00014217 ZK1086.3 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00014218 prp-40 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed in several structures, including body wall musculature; gonad; and nervous system. Is an ortholog of human PRPF40A (pre-mRNA processing factor 40 homolog A). WB:WBGene00014219 ZK1098.2 Enriched in AVK; PLM; germ line; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on RNA-seq; proteomic; and microarray studies. Is affected by eleven chemicals including D-glucose; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ribonuclease H-like superfamily and Phosphorylation site. WB:WBGene00014220 ZK1098.3 Predicted to enable 3'-5' exonuclease activity. Predicted to be involved in nucleobase-containing compound metabolic process and regulation of macromolecule metabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human EXD3 (exonuclease 3'-5' domain containing 3). WB:WBGene00014221 eif-2Balpha Enables identical protein binding activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter 1. Is an ortholog of human EIF2B1 (eukaryotic translation initiation factor 2B subunit alpha). WB:WBGene00014222 trpp-3 Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and protein secretion. Predicted to be located in cis-Golgi network membrane and cytosol. Predicted to be part of TRAPP complex. Is an ortholog of human TRAPPC3 (trafficking protein particle complex subunit 3). WB:WBGene00014223 ZK1098.6 Enriched in ABplpppaapa; ABprpppaapa; somatic gonad precursor; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and hsf-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including manganese chloride; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00014224 mrps-23 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 46. Is an ortholog of human MRPS23 (mitochondrial ribosomal protein S23). WB:WBGene00014225 ZK1098.9 Predicted to be located in membrane. WB:WBGene00014226 ZK1098.11 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; PVR; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; rotenone; and mianserin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; Gcn5-related N-acetyltransferase; Yjdj-type Gcn5-related N-acetyltransferase; and GCN5-related N-acetyl-transferase. Is an ortholog of human NATD1 (N-acetyltransferase domain containing 1). WB:WBGene00014227 ZK1128.1 Predicted to enable protein-arginine omega-N symmetric methyltransferase activity. Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Is an ortholog of human NDUFAF7 (NADH:ubiquinone oxidoreductase complex assembly factor 7). WB:WBGene00014228 mett-10 Enables U6 snRNA (adenine-(43)-N(6))-methyltransferase activity and mRNA (N6-adenosine)-methyltransferase activity. Involved in several processes, including centrosome cycle; regulation of gene expression; and vulval development. Located in nucleus. Expressed in germ line; gonad; intestine; and vulva. Is an ortholog of human METTL16 (methyltransferase 16, RNA N6-adenosine). WB:WBGene00014229 ZK1128.3 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00014230 gtf-2H3 Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and metal ion binding activity. Predicted to be involved in nucleotide-excision repair. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIH core complex and transcription factor TFIIH holo complex. Is an ortholog of human GTF2H3 (general transcription factor IIH subunit 3). WB:WBGene00014232 ttll-4 Enables tubulin-glutamic acid ligase activity. Involved in response to hermaphrodite contact. Predicted to be located in cilium. Is an ortholog of human TTLL4 (tubulin tyrosine ligase like 4). WB:WBGene00014233 ZK1128.7 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in vulval muscle. WB:WBGene00014234 vps-29 Predicted to be involved in intracellular protein transport and retrograde transport, endosome to Golgi. Located in cytosol. Is an ortholog of human VPS29 (VPS29 retromer complex component). WB:WBGene00014235 ZK1225.1 Enriched in seam cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1647) and Protein of unknown function DUF1647. WB:WBGene00014236 ZK1225.2 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00014237 ZK1225.3 No description available WB:WBGene00014238 ZK1225.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by nineteen chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00014239 ZK1225.5 Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including aldicarb; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00014240 htas-1 Predicted to enable DNA binding activity. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. Expressed in sperm and spermatid. WB:WBGene00014241 ZK1251.3 Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in steroid biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in breast carcinoma; hypospadias; and prostate cancer. Is an ortholog of human SRD5A2 (steroid 5 alpha-reductase 2). WB:WBGene00014242 sdz-36 Expressed in several structures, including Caa; Cap; Cpa; Ea; and Psub4. WB:WBGene00014243 dcaf-1 Predicted to be involved in protein ubiquitination. Predicted to be located in nucleus. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Is an ortholog of human DCAF1 (DDB1 and CUL4 associated factor 1). WB:WBGene00014244 ZK1307.1 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and Caappd based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and let-60 based on microarray; proteomic; and RNA-seq studies. Is affected by twelve chemicals including 1-methylnicotinamide; methylmercuric chloride; and Tunicamycin based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: N,N dimethylarginine dimethylhydrolase, eukaryotic. WB:WBGene00014245 ZK1307.2 Enriched in hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including Tunicamycin; D-glucose; and indole based on RNA-seq and microarray studies. WB:WBGene00014246 ZK1307.3 Enriched in NSM; OLL; PVD; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; D-glucose; and stavudine based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00014247 ZK1307.4 Enriched in NSM; sperm; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including methylmercuric chloride; rotenone; and D-glucose based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00014248 ZK1307.7 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00014249 ZK1307.8 Predicted to enable calcium ion binding activity. Involved in PERK-mediated unfolded protein response. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be part of glucosidase II complex. Human ortholog(s) of this gene implicated in polycystic liver disease. Is an ortholog of human PRKCSH (protein kinase C substrate 80K-H). WB:WBGene00014250 ZK1307.9 Predicted to be involved in RNA splicing. Predicted to be part of U2-type spliceosomal complex and post-mRNA release spliceosomal complex. Is an ortholog of human YJU2B (YJU2 splicing factor homolog B). WB:WBGene00014251 gstk-1 Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Involved in innate immune response. Located in peroxisome. Expressed in body wall musculature; hypodermis; and rectal gland cell. Is an ortholog of human GSTK1 (glutathione S-transferase kappa 1). WB:WBGene00014252 ZK1320.2 Involved in innate immune response. WB:WBGene00014253 ZK1320.3 Expressed in intestine. Is predicted to encode a protein with the following domains: Family of unknown function (DUF5352) and Protein of unknown function DUF5352. WB:WBGene00014254 cyp-13A10 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). WB:WBGene00014255 ZK1320.5 Predicted to be located in membrane. WB:WBGene00014256 ZK1320.7 Predicted to enable nucleic acid binding activity. Is an ortholog of human GPANK1 (G-patch domain and ankyrin repeats 1). WB:WBGene00014257 ZK1320.8 No description available WB:WBGene00014258 ZK1320.9 Predicted to enable acetate CoA-transferase activity and acetyl-CoA hydrolase activity. Predicted to be involved in acetate metabolic process. WB:WBGene00014259 ZK1320.11 Predicted to be located in membrane. WB:WBGene00014260 ZK1321.1 Predicted to be located in membrane. WB:WBGene00014261 shk-1 Enables delayed rectifier potassium channel activity. Involved in potassium ion transmembrane transport. Located in plasma membrane. Expressed in body wall musculature; head ganglion; interneuron; muscle cell; and sensory neurons. Human ortholog(s) of this gene implicated in several diseases, including developmental and epileptic encephalopathy 32; episodic ataxia type 1; and familial atrial fibrillation. Is an ortholog of several human genes including KCNA1 (potassium voltage-gated channel subfamily A member 1); KCNA2 (potassium voltage-gated channel subfamily A member 2); and KCNA3 (potassium voltage-gated channel subfamily A member 3). WB:WBGene00014262 ZK1321.4 Predicted to enable actin binding activity and muscle alpha-actinin binding activity. Predicted to be involved in actin cytoskeleton organization and muscle structure development. Predicted to be located in Z disc; adherens junction; and stress fiber. Predicted to be part of filamentous actin. WB:WBGene00014263 C18D4.t1 No description available WB:WBGene00014264 C24H11.t1 No description available WB:WBGene00014265 C26G2.t1 No description available WB:WBGene00014266 C28A5.7 Is affected by tdp-1 and mett-10 based on RNA-seq studies. WB:WBGene00014267 C28A5.t1 No description available WB:WBGene00014268 C28A5.t2 No description available WB:WBGene00014269 C28A5.t3 Is affected by daf-2 based on microarray studies. WB:WBGene00014270 C29F4.t1 No description available WB:WBGene00014271 C29F7.t1 No description available WB:WBGene00014272 C29F7.t2 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00014273 C29F7.t3 Is affected by daf-12 based on tiling array studies. WB:WBGene00014274 C31E10.t1 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00014275 C33G3.t2 No description available WB:WBGene00014276 C34E11.t1 No description available WB:WBGene00014277 C35D6.6 Is affected by hpl-2 based on tiling array studies. WB:WBGene00014278 C35D6.7 No description available WB:WBGene00014279 C36F7.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014280 C36F7.t2 No description available WB:WBGene00014281 C36F7.t3 No description available WB:WBGene00014282 C37A5.t1 No description available WB:WBGene00014283 C38C6.t1 No description available WB:WBGene00014284 C40C9.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014285 C40C9.t2 No description available WB:WBGene00014286 C40H5.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014287 C47E8.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014288 C47F8.9 Is affected by pmt-2 based on microarray studies. WB:WBGene00014289 C49F5.t1 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00014290 C51F7.3 Is affected by several genes including daf-2; clk-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00014291 C52E4.8 Enriched in germ line based on RNA-seq studies. Is affected by several genes including clk-1; dlc-1; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00014292 C52G5.t1 No description available WB:WBGene00014293 C53B4.9 Is affected by several genes including clk-1; cep-1; and alg-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00014294 C53C7.5 Enriched in Psub1; neurons; somatic gonad precursor; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including rotenone; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00014295 C53C7.t1 No description available WB:WBGene00014296 C53C7.t2 No description available WB:WBGene00014297 C53C7.t3 No description available WB:WBGene00014298 C53D6.t1 No description available WB:WBGene00014299 C56G7.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014300 D2023.1 Predicted to enable heme binding activity and metal ion binding activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00014301 DY3.t2 Is affected by several genes including glp-1; daf-12; and pgl-1 based on tiling array and RNA-seq studies. WB:WBGene00014302 rte-5 No description available WB:WBGene00014303 F02D10.t2 No description available WB:WBGene00014304 F02D10.t3 No description available WB:WBGene00014305 F02H6.t1 No description available WB:WBGene00014306 F07C6.5 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00014307 F07H5.3 Enriched in several structures, including coelomocyte; excretory gland cell; gonad; head mesodermal cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00014308 F07H5.4 Enriched in several structures, including body wall musculature; head mesodermal cell; intestine; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Ethanol; rotenone; and stavudine based on RNA-seq and microarray studies. WB:WBGene00014309 F07H5.5 Enriched in cholinergic neurons; dopaminergic neurons; intestine; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00014310 F08G2.9 Expressed widely. WB:WBGene00014311 F08G2.10 Is affected by daf-12 based on tiling array studies. WB:WBGene00014312 F08G2.11 Enriched in AFD based on RNA-seq studies. Is affected by dlc-1 and sftb-1 based on RNA-seq studies. WB:WBGene00014313 F08G5.t1 No description available WB:WBGene00014314 F08G5.t2 No description available WB:WBGene00014315 F08G5.t3 Is affected by daf-2 based on microarray studies. WB:WBGene00014316 F08H9.10 Is affected by adr-2; sftb-1; and etr-1 based on RNA-seq studies. WB:WBGene00014317 F08H9.11 Is affected by daf-16; sftb-1; and etr-1 based on RNA-seq studies. WB:WBGene00014318 F09B9.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014319 F09B9.t2 Is affected by daf-12 based on tiling array studies. WB:WBGene00014320 F11A1.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014321 F11A1.t2 No description available WB:WBGene00014322 F11A5.14 Enriched in germ line based on RNA-seq studies. Is affected by several genes including cep-1; set-2; and fzo-1 based on RNA-seq studies. WB:WBGene00014323 F11A5.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014324 F13G11.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014325 F14B4.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014326 F14B4.t2 No description available WB:WBGene00014327 F14B6.t1 No description available WB:WBGene00014328 F14B6.t2 No description available WB:WBGene00014329 F14F7.t1 No description available WB:WBGene00014330 F14H8.t1 No description available WB:WBGene00014331 F15B9.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014332 F15D3.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014333 F15G9.t1 No description available WB:WBGene00014334 F15G9.t2 No description available WB:WBGene00014335 F15H9.5 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00014336 F15H9.6 Is affected by sftb-1 and rnp-6 based on RNA-seq studies. WB:WBGene00014337 F15H9.t1 No description available WB:WBGene00014338 F17A2.t1 No description available WB:WBGene00014339 F17H10.t1 No description available WB:WBGene00014340 F19H6.t1 No description available WB:WBGene00014341 F21A3.t1 No description available WB:WBGene00014342 F21A3.t2 Is affected by daf-12 based on tiling array studies. WB:WBGene00014343 F21C3.t1 Is affected by emr-1; lem-2; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00014344 F22G12.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014345 F22G12.t2 No description available WB:WBGene00014346 F23A7.t1 No description available WB:WBGene00014347 F23D12.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014348 F23D12.t2 No description available WB:WBGene00014349 F27D4.t1 No description available WB:WBGene00014350 F28F8.t1 No description available WB:WBGene00014351 F28F8.t2 No description available WB:WBGene00014352 F28F8.t3 No description available WB:WBGene00014353 F28F8.t4 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00014354 F28H6.t1 No description available WB:WBGene00014355 F28H6.t2 No description available WB:WBGene00014356 F28H6.t3 No description available WB:WBGene00014357 F28H6.t4 No description available WB:WBGene00014358 F28H6.t5 No description available WB:WBGene00014359 F28H6.t6 No description available WB:WBGene00014360 F28H6.t7 No description available WB:WBGene00014361 F31B12.t1 No description available WB:WBGene00014362 F31E9.t1 No description available WB:WBGene00014363 F32B4.t1 No description available WB:WBGene00014364 F34H10.t1 Is affected by daf-12 and mrps-5 based on tiling array and RNA-seq studies. WB:WBGene00014365 F35H8.t1 No description available WB:WBGene00014366 F38E11.10 Is affected by daf-12 and sftb-1 based on tiling array and RNA-seq studies. WB:WBGene00014367 F38E11.11 Is affected by sftb-1 based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00014368 F39B1.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014369 F39B1.t2 No description available WB:WBGene00014370 F40G12.13 Is affected by several genes including daf-16; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00014371 F40G12.14 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00014372 F42D1.t1 No description available WB:WBGene00014373 F42F12.t1 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00014374 F42G10.t1 No description available WB:WBGene00014375 F44D12.11 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by nine chemicals including manganese chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014376 F45G2.t1 No description available WB:WBGene00014377 F47A4.t1 No description available WB:WBGene00014378 F49C5.t1 No description available WB:WBGene00014379 F49C5.t2 No description available WB:WBGene00014380 F49C5.t3 No description available WB:WBGene00014381 F49C5.t4 No description available WB:WBGene00014382 F49E2.t1 No description available WB:WBGene00014384 F52E10.t1 Is affected by daf-12; clk-1; and daf-2 based on tiling array and microarray studies. WB:WBGene00014385 F52E10.t2 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00014386 F52E10.t3 No description available WB:WBGene00014387 F52E10.t4 Is affected by daf-2 based on microarray studies. WB:WBGene00014388 F52E10.t5 Is affected by daf-12 based on tiling array studies. WB:WBGene00014389 F53B6.t1 No description available WB:WBGene00014390 F53F8.t1 No description available WB:WBGene00014391 mir-392 Is affected by several genes including daf-12; prg-1; and alg-1 based on tiling array and RNA-seq studies. Is affected by graphene oxide and sanguinarine based on RNA-seq studies. WB:WBGene00014392 F54C8.8 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00014393 F54C8.9 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00014394 F54C8.10 Is affected by adr-1 and mett-10 based on RNA-seq studies. WB:WBGene00014395 F54F7.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014396 F54F7.t2 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014397 F55A11.10 Is affected by cep-1 and daf-2 based on RNA-seq studies. WB:WBGene00014398 F55F3.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014399 F55F3.t2 Is affected by daf-12 based on tiling array studies. WB:WBGene00014400 F55G7.t1 No description available WB:WBGene00014401 F55G7.t2 No description available WB:WBGene00014402 F56F3.t1 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00014403 F56H6.14 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00014404 F56H6.15 Is affected by prg-1; sftb-1; and etr-1 based on RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00014405 F56H6.16 Enriched in germ line based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00014406 F57F5.t1 No description available WB:WBGene00014407 F57G8.t1 No description available WB:WBGene00014408 F57G8.t2 No description available WB:WBGene00014409 F57G8.t3 No description available WB:WBGene00014410 F57G8.t4 No description available WB:WBGene00014411 F58D5.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014413 H06A10.t1 No description available WB:WBGene00014414 K01A6.t1 No description available WB:WBGene00014415 K01A11.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014416 K02A4.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014417 K02A4.t2 Is affected by daf-12 based on tiling array studies. WB:WBGene00014418 K02B12.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014419 K02E2.t1 No description available WB:WBGene00014420 K02E11.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014421 K03B8.10 Is affected by several genes including cep-1; hpl-2; and set-2 based on RNA-seq studies. WB:WBGene00014422 K03B8.t1 No description available WB:WBGene00014423 K06A4.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014424 K07A1.t1 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00014425 K07C10.2 Enriched in neurons based on RNA-seq studies. Is affected by rsr-2 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00014426 K07C10.t1 No description available WB:WBGene00014427 K08E7.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014428 K08H2.t1 No description available WB:WBGene00014429 K09A11.t1 No description available WB:WBGene00014430 K09B11.11 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00014431 K09B11.12 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00014432 K09B11.13 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00014433 K09B11.14 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00014434 K09B11.15 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00014435 K09B11.16 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00014436 K09C8.t1 No description available WB:WBGene00014437 K10C8.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014438 K11E4.t1 No description available WB:WBGene00014439 K11E4.t2 Is affected by clk-1 based on microarray studies. WB:WBGene00014440 K11E4.t3 No description available WB:WBGene00014441 K11E4.t4 Is affected by daf-12 and hmg-3 based on tiling array and RNA-seq studies. WB:WBGene00014442 K11E4.t5 Is affected by daf-12 and hmg-3 based on tiling array and RNA-seq studies. WB:WBGene00014443 K11E4.t6 Is affected by daf-12 based on tiling array studies. WB:WBGene00014444 K11H3.t1 Is affected by adr-1 and mrps-5 based on RNA-seq studies. WB:WBGene00014445 K11H3.t2 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00014446 M01E5.t1 No description available WB:WBGene00014447 M106.6 Enriched in AFD based on RNA-seq studies. WB:WBGene00014448 M163.t1 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00014449 M163.t2 No description available WB:WBGene00014450 MTCE.1 No description available WB:WBGene00014451 MTCE.2 Enriched in sensory neurons based on RNA-seq studies. Is affected by prg-1; mett-10; and camt-1 based on RNA-seq studies. WB:WBGene00014452 MTCE.5 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including prg-1; rpl-5; and olrn-1 based on RNA-seq studies. WB:WBGene00014453 MTCE.6 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00014454 MTCE.7 Enriched in cholinergic neurons; dopaminergic neurons; gonadal sheath cell; and pharyngeal neurons based on single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and hsp-6 based on RNA-seq and microarray studies. Is affected by four chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00014455 MTCE.8 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00014456 MTCE.9 Is affected by prg-1; rpl-33; and rpl-5 based on RNA-seq studies. WB:WBGene00014457 MTCE.10 Is affected by camt-1 and sams-3 based on RNA-seq studies. WB:WBGene00014458 MTCE.13 Is affected by olrn-1 based on RNA-seq studies. WB:WBGene00014459 MTCE.14 Is affected by daf-2 based on microarray studies. WB:WBGene00014460 MTCE.15 Is affected by rnp-6 based on RNA-seq studies. WB:WBGene00014461 MTCE.17 Is affected by prg-1 and rnp-6 based on RNA-seq studies. WB:WBGene00014462 MTCE.18 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00014463 MTCE.19 Is affected by prg-1; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00014464 MTCE.20 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00014465 MTCE.22 Is affected by aak-2; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00014466 MTCE.24 Is affected by prg-1; mett-10; and etr-1 based on RNA-seq studies. Is affected by Ketamine based on RNA-seq studies. WB:WBGene00014467 MTCE.27 No description available WB:WBGene00014468 MTCE.28 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00014469 MTCE.29 No description available WB:WBGene00014470 MTCE.30 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; prg-1; and zip-3 based on RNA-seq and microarray studies. WB:WBGene00014471 MTCE.32 Is affected by daf-2 based on microarray studies. WB:WBGene00014472 MTCE.33 Enriched in command interneuron and nerve ring neurons based on single-cell RNA-seq studies. Is affected by several genes including hsf-1; npr-1; and sek-1 based on RNA-seq studies. Is affected by five chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00014473 MTCE.36 No description available WB:WBGene00014474 R01H5.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014475 R03E1.t1 No description available WB:WBGene00014476 R03E1.t2 No description available WB:WBGene00014477 R04D3.t1 No description available WB:WBGene00014478 R04D3.t2 No description available WB:WBGene00014479 R04D3.t3 No description available WB:WBGene00014480 R04D3.t4 Is affected by clk-1 based on microarray studies. WB:WBGene00014481 R04D3.t5 No description available WB:WBGene00014482 R04F11.t1 No description available WB:WBGene00014483 R05D7.6 No description available WB:WBGene00014484 R07E5.16 Is affected by mett-10; let-418; and dcp-66 based on RNA-seq studies. WB:WBGene00014485 R09E10.t1 Is affected by lem-2 based on RNA-seq studies. WB:WBGene00014486 R11.t1 No description available WB:WBGene00014487 R11.t2 No description available WB:WBGene00014488 R11.t3 No description available WB:WBGene00014489 R11.t4 No description available WB:WBGene00014490 R11G10.t1 No description available WB:WBGene00014491 R11G10.t2 No description available WB:WBGene00014493 T01B4.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014494 T01B4.t2 No description available WB:WBGene00014495 T01B4.t3 Is affected by elli-1 and daf-2 based on microarray studies. WB:WBGene00014496 T01B4.t4 No description available WB:WBGene00014497 T01C1.t1 No description available WB:WBGene00014498 T02G6.t1 No description available WB:WBGene00014499 T03E6.t1 No description available WB:WBGene00014500 T04D3.t1 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00014501 T04D3.t2 No description available WB:WBGene00014502 T04D3.t3 No description available WB:WBGene00014503 T04D3.t4 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014504 T04F8.t1 No description available WB:WBGene00014505 T05E11.9 Enriched in coelomocyte; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercury hydroxide; 1-methylnicotinamide; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00014506 T06D8.11 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00014507 T06H11.t1 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00014508 T06H11.t2 No description available WB:WBGene00014509 T06H11.t3 No description available WB:WBGene00014510 T07D10.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014511 T08G5.11 Is affected by several genes including daf-16; meg-3; and meg-4 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00014512 T09F5.t1 No description available WB:WBGene00014513 T10B9.t1 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00014514 T10B10.t1 No description available WB:WBGene00014515 T10B10.t2 No description available WB:WBGene00014516 hpo-42 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including manganese chloride; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00014517 T11F9.15 Is affected by dlc-1 and sftb-1 based on RNA-seq studies. WB:WBGene00014518 T11F9.16 Is affected by several genes including clk-1; cep-1; and dlc-1 based on RNA-seq and microarray studies. WB:WBGene00014519 T14G8.t1 Is affected by daf-2 based on RNA-seq studies. WB:WBGene00014520 T18D3.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014521 T19C4.t1 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00014522 T20D3.12 No description available WB:WBGene00014523 T20D3.13 No description available WB:WBGene00014524 T21B4.t1 No description available WB:WBGene00014525 T22A3.t1 No description available WB:WBGene00014526 T22A3.t2 No description available WB:WBGene00014527 T22A3.t3 Is affected by clk-1 based on microarray studies. WB:WBGene00014528 T22A3.t4 No description available WB:WBGene00014529 T22C1.t1 No description available WB:WBGene00014530 T22C8.t1 No description available WB:WBGene00014531 T23F1.t1 No description available WB:WBGene00014532 T23F1.t2 No description available WB:WBGene00014533 T23H4.t1 No description available WB:WBGene00014534 mir-355 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00014535 T28D6.t1 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00014536 T28D6.t2 Is affected by daf-12 based on tiling array studies. WB:WBGene00014537 VK10D6R.t1 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00014538 W02H3.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00014539 W03C9.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014540 W03G11.t1 No description available WB:WBGene00014541 W04D2.7 Is affected by several genes including daf-16; daf-2; and hpl-2 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00014542 W04G5.11 Enriched in germ line based on RNA-seq studies. Is affected by several genes including cep-1; hpl-2; and dlc-1 based on tiling array and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00014543 W05B2.8 Is affected by several genes including dpy-21; tdp-1; and hmg-3 based on RNA-seq studies. WB:WBGene00014544 W05B2.t1 No description available WB:WBGene00014545 W06D4.t1 No description available WB:WBGene00014546 W06G6.t1 No description available WB:WBGene00014547 W06G6.t2 No description available WB:WBGene00014548 W06G6.t3 No description available WB:WBGene00014549 W07G1.8 Is affected by dlc-1 and sftb-1 based on RNA-seq studies. WB:WBGene00014550 W07G1.9 No description available WB:WBGene00014551 W07G4.t1 No description available WB:WBGene00014552 W09D6.t1 No description available WB:WBGene00014553 W09D6.t2 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00014554 Y7A5A.t1 No description available WB:WBGene00014555 Y7A5A.t2 No description available WB:WBGene00014556 Y7A5A.t3 No description available WB:WBGene00014557 Y7A5A.t4 No description available WB:WBGene00014558 Y7A5A.t5 No description available WB:WBGene00014559 Y7A9D.t1 No description available WB:WBGene00014560 Y7A9D.t2 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014561 Y7A9D.t3 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014562 Y17D7B.7 Enriched in SAA; head mesodermal cell; mechanosensory neurons; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercury hydroxide; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014563 Y37A1B.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014564 Y38E10A.t1 Is affected by daf-12 and adr-1 based on tiling array and RNA-seq studies. WB:WBGene00014565 Y38H6A.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014566 Y39A1A.t1 No description available WB:WBGene00014567 Y39B6A.t9 No description available WB:WBGene00014568 Y39B6A.t10 No description available WB:WBGene00014569 bkip-1 Enables transmembrane transporter binding activity. Located in neuron projection and striated muscle dense body. Expressed in body wall musculature; head mesodermal cell; muscle cell; neurons; and somatic nervous system. WB:WBGene00014570 Y40H7A.t1 No description available WB:WBGene00014571 Y40H7A.t2 No description available WB:WBGene00014572 Y43D4A.t1 No description available WB:WBGene00014573 Y43D4A.t2 No description available WB:WBGene00014574 Y43F4A.t1 No description available WB:WBGene00014575 Y43F4A.t2 No description available WB:WBGene00014576 Y43F11A.6 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; manganese chloride; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014577 Y47H9A.2 Is affected by hpl-2 and sftb-1 based on tiling array and RNA-seq studies. WB:WBGene00014578 Y49E10.t1 No description available WB:WBGene00014579 Y51A2B.t1 No description available WB:WBGene00014580 Y51H4A.t2 Is affected by adr-1 based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00014581 Y51H4A.t3 No description available WB:WBGene00014582 Y51H4A.t4 Is affected by daf-2 based on microarray studies. WB:WBGene00014583 Y51H4A.t5 No description available WB:WBGene00014584 Y51H4A.t6 No description available WB:WBGene00014585 Y53C10A.t1 No description available WB:WBGene00014586 rte-2 No description available WB:WBGene00014587 Y53C10A.t3 No description available WB:WBGene00014588 Y53C12A.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014589 Y54G9A.8 Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq and microarray studies. WB:WBGene00014590 Y57A10B.t1 No description available WB:WBGene00014591 Y57A10C.t1 Is affected by elli-1 based on microarray studies. WB:WBGene00014592 Y57G11B.t1 No description available WB:WBGene00014593 Y57G11C.35 Is affected by daf-12; cep-1; and sftb-1 based on tiling array and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00014594 Y57G11C.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014595 Y59A8B.t3 No description available WB:WBGene00014596 Y65A5A.t1 No description available WB:WBGene00014597 Y65A5A.t2 No description available WB:WBGene00014598 Y65A5A.t3 No description available WB:WBGene00014599 Y65A5A.t4 No description available WB:WBGene00014600 Y66D12A.t1 No description available WB:WBGene00014601 Y70C5A.t1 No description available WB:WBGene00014602 Y73F8A.t1 No description available WB:WBGene00014603 Y73F8A.t3 No description available WB:WBGene00014604 Y73F8A.t4 No description available WB:WBGene00014605 Y95D11A.t1 No description available WB:WBGene00014606 Y105C5A.t1 No description available WB:WBGene00014607 Y105C5A.t2 No description available WB:WBGene00014608 Y105C5B.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014609 Y105C5B.t2 No description available WB:WBGene00014610 Y105C5B.t3 No description available WB:WBGene00014611 Y105C5B.t4 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014612 mir-354 Is affected by several genes including daf-12; alg-1; and alg-2 based on tiling array and RNA-seq studies. WB:WBGene00014613 Y111B2A.25 Enriched in AVK and germ line based on RNA-seq studies. Is affected by several genes including clk-1; dcr-1; and unc-30 based on RNA-seq and microarray studies. Is affected by paraquat and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00014614 Y113G7B.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014615 Y116F11A.4 Is affected by several genes including daf-2; age-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014616 Y116F11A.t1 No description available WB:WBGene00014617 ZC412.t1 No description available WB:WBGene00014618 ZC412.t2 Is affected by daf-2 based on RNA-seq studies. WB:WBGene00014619 ZC455.t1 Is affected by daf-2 based on RNA-seq studies. WB:WBGene00014620 ZK39.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00014621 rrn-4.1 No description available WB:WBGene00014622 sls-1.10 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00014623 ZK262.t1 No description available WB:WBGene00014624 ZK507.t1 No description available WB:WBGene00014625 ZK617.t1 No description available WB:WBGene00014626 ZK678.t1 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00014627 ZK678.t2 No description available WB:WBGene00014628 ZK678.t3 No description available WB:WBGene00014629 ZK678.t5 Is affected by clk-1 based on microarray studies. WB:WBGene00014630 ZK822.t1 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00014631 ZK897.2 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00014632 ZK897.3 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; alg-1; and sftb-1 based on RNA-seq studies. WB:WBGene00014633 ZK897.4 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00014634 ZK899.t1 No description available WB:WBGene00014635 ZK970.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014636 ZK970.t2 No description available WB:WBGene00014637 ZK970.t3 No description available WB:WBGene00014638 ZK970.t4 No description available WB:WBGene00014639 ZK1010.t1 Is affected by swsn-1 based on RNA-seq studies. WB:WBGene00014640 ZK1067.t1 No description available WB:WBGene00014641 B0285.11 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00014643 B0391.8 Enriched in germ line and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014644 B0399.t1 No description available WB:WBGene00014645 B0399.t2 Is affected by daf-2 and camt-1 based on microarray and RNA-seq studies. WB:WBGene00014646 B0399.t3 No description available WB:WBGene00014647 B0399.t4 Is affected by clk-1 based on microarray studies. WB:WBGene00014648 B0399.t5 No description available WB:WBGene00014649 B0399.t6 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00014650 B0399.t7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00014651 B0399.t8 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00014652 B0399.t9 Enriched in sensory neurons based on RNA-seq studies. Is affected by clk-1 based on microarray studies. WB:WBGene00014653 B0399.t10 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00014654 B0399.t11 No description available WB:WBGene00014655 B0399.t12 Is affected by clk-1 based on microarray studies. WB:WBGene00014656 B0399.t13 No description available WB:WBGene00014657 B0399.t14 Is affected by daf-2 based on microarray studies. WB:WBGene00014658 B0399.t15 No description available WB:WBGene00014659 B0399.t16 No description available WB:WBGene00014660 B0457.3 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by six chemicals including cholesterol; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00014663 C01G6.10 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and unc-30 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq studies. WB:WBGene00014664 C04F12.t1 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00014665 C04G2.3 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including Ethanol; methylmercury hydroxide; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00014666 C05D12.3 Enriched in body wall muscle cell; intestine; and neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; microarray; and proteomic studies. Is affected by twenty-eight chemicals including nicotinic acid; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: von Willebrand factor A-like domain superfamily. WB:WBGene00014667 C06A1.4 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00014668 C06C3.9 Enriched in ABplpappaa; excretory system; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; elt-2; and pmk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014669 zipt-2.1 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human SLC39A1 (solute carrier family 39 member 1) and SLC39A2 (solute carrier family 39 member 2). WB:WBGene00014670 C08E8.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014671 C08E8.t2 No description available WB:WBGene00014672 C08F11.6 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Alovudine; and allantoin based on RNA-seq studies. WB:WBGene00014673 C08H9.9 Is affected by several genes including daf-16; eat-2; and smg-2 based on RNA-seq and microarray studies. Is affected by adsorbable organic bromine compound and Sirolimus based on microarray studies. WB:WBGene00014674 C12D8.2 Is affected by daf-2 and eat-2 based on microarray studies. Is affected by triclosan based on microarray studies. WB:WBGene00014675 C12D8.3 Is affected by daf-2; eat-2; and flcn-1 based on microarray studies. Is affected by Colistin and triclosan based on microarray studies. WB:WBGene00014676 C12D8.7 Is affected by clk-1; daf-2; and eat-2 based on microarray studies. WB:WBGene00014677 C14B4.t1 No description available WB:WBGene00014678 C15H7.2 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00014679 srz-25 Predicted to be located in membrane. WB:WBGene00014681 C25D7.14 Is affected by several genes including daf-2; dpy-10; and lin-4 based on RNA-seq and microarray studies. Is affected by nine chemicals including multi-walled carbon nanotube; Doxycycline; and Acrylamide based on RNA-seq and microarray studies. WB:WBGene00014682 C25F9.t1 No description available WB:WBGene00014683 C25F9.t2 No description available WB:WBGene00014684 C25F9.t3 No description available WB:WBGene00014685 C25F9.t4 No description available WB:WBGene00014686 C25F9.t5 Is affected by clk-1 and eat-2 based on microarray and RNA-seq studies. WB:WBGene00014689 C28D4.11 Is affected by daf-16 based on RNA-seq studies. WB:WBGene00014691 C33A11.t1 Is affected by daf-2 based on microarray studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00014692 C33A12.17 Is affected by eat-2 and simr-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014693 C33A12.18 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00014694 C33D3.2 Is affected by alg-1; eat-2; and etr-1 based on RNA-seq studies. Is affected by metformin and Sirolimus based on RNA-seq studies. WB:WBGene00014695 C33G3.t1 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00014696 C33G3.t3 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00014697 cyp-25A3 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. WB:WBGene00014698 C37A5.3 Predicted to be involved in innate immune response. WB:WBGene00014699 C37A5.5 Predicted to be involved in innate immune response. WB:WBGene00014700 C37A5.6 Predicted to be involved in innate immune response. WB:WBGene00014701 C43D7.1 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00014702 C43D7.3 Is affected by several genes including skn-1; eat-2; and pgl-1 based on RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00014703 C47A4.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and hpl-2 based on RNA-seq and microarray studies. Is affected by cholesterol; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00014704 C47A10.t1 No description available WB:WBGene00014705 C47A10.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00014706 C47A10.t3 No description available WB:WBGene00014707 C47A10.t4 No description available WB:WBGene00014708 C47A10.t5 Is affected by daf-2 based on microarray studies. WB:WBGene00014709 C48D1.6 No description available WB:WBGene00014710 C50B6.13 Is affected by several genes including eat-2; let-418; and adr-1 based on RNA-seq studies. WB:WBGene00014711 C50F4.15 Is affected by clk-1 and etr-1 based on microarray and RNA-seq studies. Is affected by nitroguanidine based on microarray studies. WB:WBGene00014712 C50H2.9 No description available WB:WBGene00014714 C54C8.8 Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00014715 C54E10.t1 No description available WB:WBGene00014716 C54E10.t2 No description available WB:WBGene00014717 C54E10.t3 No description available WB:WBGene00014718 C54E10.t4 No description available WB:WBGene00014719 C54E10.t5 No description available WB:WBGene00014720 C54E10.t6 No description available WB:WBGene00014721 C54E10.t7 No description available WB:WBGene00014722 C55A1.13 No description available WB:WBGene00014723 srz-49 No description available WB:WBGene00014724 D1046.t1 No description available WB:WBGene00014727 DY3.t1 No description available WB:WBGene00014728 E03A3.1 Enriched in sensory neurons and in male based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and npr-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00014729 E03H4.9 Is affected by several genes including eat-2; hpl-2; and hda-2 based on RNA-seq studies. Is affected by Sirolimus based on RNA-seq studies. WB:WBGene00014730 F01D5.4 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014731 F02E9.8 Is affected by several genes including eat-2; let-418; and dlc-1 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00014732 F09F3.8 Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including multi-walled carbon nanotube; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00014733 F10A3.10 Is affected by clk-1 based on microarray studies. WB:WBGene00014734 F11A3.3 Is affected by several genes including eat-2; hpl-2; and etr-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014735 cyp-35D2 Is affected by dpy-21 and hda-2 based on RNA-seq studies. WB:WBGene00014738 F19H8.t1 No description available WB:WBGene00014739 F21D9.7 No description available WB:WBGene00014740 F21H7.6 Is affected by qui-1 based on RNA-seq studies. WB:WBGene00014741 F22B8.2 Is affected by several genes including daf-16; daf-12; and hpl-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00014744 F25H9.9 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00014745 F26D2.8 Is affected by eat-2 based on RNA-seq studies. Is affected by Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014746 F27D4.3 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00014748 F30F8.t1 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00014751 F36G9.4 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00014752 F38E11.8 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014753 F40D4.14 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00014754 F40F9.11 Enriched in intestine based on microarray studies. Is affected by hpl-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and resveratrol based on RNA-seq and microarray studies. WB:WBGene00014755 F40F12.8 Enriched in sensory neurons and in male based on RNA-seq studies. Is affected by several genes including glp-1; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including Sodium Chloride; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00014757 F44G3.4 No description available WB:WBGene00014758 F45H7.t1 No description available WB:WBGene00014759 F46A8.1 Is affected by several genes including daf-16; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; paraquat; and CGP37157 based on RNA-seq and microarray studies. WB:WBGene00014760 F46A8.2 Is affected by several genes including rrf-3; pgl-1; and lin-35 based on microarray and RNA-seq studies. Is affected by stavudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014761 F46A8.11 Enriched in excretory gland cell and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; glp-1; and daf-12 based on RNA-seq and microarray studies. Is affected by six chemicals including rotenone; Cry5B; and paraquat based on RNA-seq and microarray studies. WB:WBGene00014763 F46F2.t1 Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00014764 srz-46 Enriched in ASH based on single-cell RNA-seq studies. Is affected by eat-2; etr-1; and mrps-5 based on microarray and RNA-seq studies. Is affected by nitroguanidine based on microarray studies. WB:WBGene00014766 F49E11.t1 No description available WB:WBGene00014767 F49E11.t2 No description available WB:WBGene00014768 F49H6.6 Is affected by qui-1 based on RNA-seq studies. WB:WBGene00014769 F53B2.7 Is affected by several genes including daf-16; daf-18; and atfs-1 based on RNA-seq studies. WB:WBGene00014770 F54F3.2 Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including stavudine; paraquat; and Heme based on RNA-seq and microarray studies. WB:WBGene00014771 F55G11.3 Is affected by several genes including daf-2; age-1; and daf-12 based on microarray and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00014772 F56D5.4 Enriched in AVK; germ line; head mesodermal cell; and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; sir-2.1; and sek-1 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014773 F56D5.8 Is affected by several genes including clk-1; pgl-1; and alg-1 based on microarray and RNA-seq studies. WB:WBGene00014774 F57G4.7 No description available WB:WBGene00014775 F57G12.t1 No description available WB:WBGene00014776 F57G12.t2 No description available WB:WBGene00014777 F58A4.12 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; cholesterol; and Doxycycline based on RNA-seq studies. WB:WBGene00014778 F58D12.2 Is affected by dlc-1; eat-2; and daf-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00014779 F59A1.2 No description available WB:WBGene00014781 F59A1.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014782 F59A1.t2 No description available WB:WBGene00014783 F59A1.t3 Is affected by clk-1 based on microarray studies. WB:WBGene00014784 F59A1.t4 No description available WB:WBGene00014785 F59A1.t5 Is affected by clk-1 based on microarray studies. WB:WBGene00014786 F59A1.t6 Is affected by daf-2 based on microarray studies. WB:WBGene00014787 F59A1.t7 Is affected by clk-1 based on microarray studies. WB:WBGene00014788 F59A1.t8 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00014789 F59C6.10 Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00014790 H03G16.3 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and tetrabromobisphenol A based on RNA-seq and microarray studies. WB:WBGene00014793 H40L08.2 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and ABarpppapa based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Heme; rotenone; and procyanidin based on microarray and RNA-seq studies. WB:WBGene00014794 K02E2.5 Is affected by several genes including eat-2; sir-2.1; and dlc-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014795 K03D7.1 No description available WB:WBGene00014796 K03D7.3 Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. WB:WBGene00014798 K05D4.1 Is affected by etr-1 and qui-1 based on RNA-seq studies. WB:WBGene00014799 K05D4.5 Is affected by several genes including sir-2.1; qui-1; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00014800 nhr-200 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00014801 K08E5.1 Enriched in AIBL and AIBR based on single-cell RNA-seq studies. Is affected by several genes including daf-16; lin-35; and cep-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; stavudine; and allantoin based on RNA-seq studies. WB:WBGene00014803 K08G2.14 Is affected by resveratrol based on microarray studies. WB:WBGene00014805 K08H10.5 Is affected by several genes including daf-2; eat-2; and hsp-6 based on RNA-seq and microarray studies. Is affected by methylmercury hydroxide; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00014806 M01G12.8 Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00014807 M04D5.1 Predicted to enable protein disulfide isomerase activity. Predicted to be involved in protein folding and response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Is an ortholog of human P4HB (prolyl 4-hydroxylase subunit beta); PDIA2 (protein disulfide isomerase family A member 2); and PDILT (protein disulfide isomerase like, testis expressed). WB:WBGene00014809 M142.3 Enriched in PHC based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by cholesterol; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00014811 M162.9 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and unc-30 based on RNA-seq and microarray studies. Is affected by stavudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014813 M176.9 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00014814 R03D7.3 Is affected by several genes including eat-2; elt-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014817 R07B5.1 Enriched in AVK based on RNA-seq studies. WB:WBGene00014818 R07B5.2 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00014819 R08A2.6 No description available WB:WBGene00014820 R09B3.6 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including eat-2; unc-30; and nuo-6 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00014821 R10E8.7 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014822 R11H6.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014824 R12G8.t2 No description available WB:WBGene00014825 R13.5 Is affected by pptr-1 and etr-1 based on RNA-seq studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00014826 R13H4.2 Enriched in head mesodermal cell; muscle cell; rectal epithelial cell; and rectum based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; microarray; and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; nicotinic acid; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00014827 T01B7.1 Is affected by clk-1 and sir-2.1 based on microarray studies. Is affected by allantoin based on microarray studies. WB:WBGene00014828 T01G1.t1 No description available WB:WBGene00014829 T01G1.t2 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014831 T04A11.11 No description available WB:WBGene00014832 srab-27 No description available WB:WBGene00014833 T07C12.4 Is affected by clk-1 based on microarray studies. WB:WBGene00014834 T08G5.4 Is affected by daf-16 based on RNA-seq studies. WB:WBGene00014835 T09F5.4 Is affected by etr-1 and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00014836 T09F5.12 Enriched in AFD; PLM; sensory neurons; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including methylmercury hydroxide; rotenone; and 4-bromodiphenyl ether based on RNA-seq and microarray studies. WB:WBGene00014837 T09F5.13 Is affected by alg-1; etr-1; and let-60 based on RNA-seq and microarray studies. Is affected by Cholestanol based on microarray studies. WB:WBGene00014838 cyp-13A9 Is affected by several genes including daf-16; eat-2; and nhr-49 based on RNA-seq and microarray studies. Is affected by paraquat; bortezomib; and cadmium based on RNA-seq studies. WB:WBGene00014839 T10H4.1 Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00014841 T19C4.10 Is affected by clk-1 based on microarray studies. WB:WBGene00014842 clec-30 Is affected by several genes including clk-1; smg-2; and etr-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00014843 T21H8.t1 Is affected by emb-4; hrde-1; and lpd-3 based on RNA-seq studies. WB:WBGene00014844 T23D5.5 Is affected by clk-1 based on microarray studies. WB:WBGene00014845 T23F1.2 No description available WB:WBGene00014846 T26H5.6 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00014847 T27F6.9 No description available WB:WBGene00014848 VM106R.1 Predicted to be involved in protein homooligomerization. Is an ortholog of human KCTD12 (potassium channel tetramerization domain containing 12). WB:WBGene00014849 VW02B12L.t1 No description available WB:WBGene00014850 VW02B12L.t2 Is affected by prg-1 and eat-2 based on RNA-seq studies. WB:WBGene00014851 W01G7.2 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00014852 W02A11.6 Is affected by several genes including eat-2; pgl-1; and unc-30 based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; Rifampin; and Psoralens based on RNA-seq studies. WB:WBGene00014853 W02A11.t1 No description available WB:WBGene00014854 W05B2.3 Enriched in somatic gonad precursor and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by Doxycycline; paraquat; and Colistin based on RNA-seq and microarray studies. WB:WBGene00014855 W06D12.t1 No description available WB:WBGene00014856 W06D12.t2 No description available WB:WBGene00014857 W08D2.9 Enriched in neurons and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on RNA-seq and microarray studies. Is affected by ten chemicals including Ethanol; paraquat; and Quercetin based on RNA-seq and microarray studies. WB:WBGene00014858 W09C5.3 Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; metformin; and Psoralens based on RNA-seq studies. WB:WBGene00014861 Y6B3B.2 Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including methylmercury hydroxide; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00014862 Y7A9C.2 Is affected by clk-1 based on microarray studies. WB:WBGene00014863 Y11D7A.16 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including eat-2; prg-1; and hmg-3 based on RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00014864 Y18D10A.22 Enriched in AFD and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by four chemicals including Tunicamycin; stavudine; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00014865 Y26G10.t1 No description available WB:WBGene00014866 Y26G10.t2 No description available WB:WBGene00014867 Y26G10.t3 Is affected by clk-1 based on microarray studies. WB:WBGene00014868 Y32B12B.t1 No description available WB:WBGene00014869 Y32B12B.t2 No description available WB:WBGene00014870 Y37H9A.4 Enriched in germ line based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Alovudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00014871 Y37H9A.5 Enriched in ABplapaaaap; ABprapaaaap; B cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00014872 Y38E10A.t2 Is affected by clk-1 based on microarray studies. WB:WBGene00014873 Y38E10A.t3 No description available WB:WBGene00014874 Y38H6A.4 Is affected by several genes including eat-2; unc-30; and hpl-2 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00014875 Y39B6A.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014876 Y39B6A.t2 No description available WB:WBGene00014877 Y39B6A.t3 Is affected by clk-1 based on microarray studies. WB:WBGene00014878 Y39B6A.t4 No description available WB:WBGene00014879 Y39B6A.t5 No description available WB:WBGene00014880 Y39B6A.t6 No description available WB:WBGene00014881 Y39B6A.t7 No description available WB:WBGene00014882 Y39B6A.t8 No description available WB:WBGene00014883 Y39C12A.2 Is affected by several genes including daf-16; glp-1; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00014884 Y39E4B.14 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00014885 Y39G8B.8 Is affected by vhl-1; ints-5; and sir-2.1 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00014886 Y41E3.5 Enriched in ADF; ASI; ASJ; head mesodermal cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. WB:WBGene00014887 Y43F8A.t1 No description available WB:WBGene00014888 Y43F8B.8 Is affected by several genes including rrf-3; eat-2; and alg-1 based on RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00014889 Y43F8C.t1 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00014890 Y43F8C.t2 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00014891 Y43F8C.t3 No description available WB:WBGene00014892 Y43F8C.t4 No description available WB:WBGene00014893 Y43F8C.t5 No description available WB:WBGene00014894 Y43F8C.t6 No description available WB:WBGene00014895 Y43F8C.t7 Is affected by clk-1 based on microarray studies. WB:WBGene00014896 Y43F8C.t8 No description available WB:WBGene00014897 Y43F8C.t9 Enriched in sensory neurons based on RNA-seq studies. Is affected by clk-1 and dpy-21 based on microarray and RNA-seq studies. WB:WBGene00014898 Y45F3A.6 Is affected by eat-2 and etr-1 based on RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00014902 Y49E10.5 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and atfs-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014903 Y49E10.8 Enriched in ALM and PLM based on microarray studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube and Colistin based on RNA-seq and microarray studies. WB:WBGene00014904 Y49E10.26 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on RNA-seq and microarray studies. Is affected by ten chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00014905 Y51A2A.2 Is affected by several genes including daf-2; eat-2; and hsp-6 based on microarray and RNA-seq studies. WB:WBGene00014906 fbxa-109 Is affected by wdr-5.1 and hlh-26 based on RNA-seq studies. Is affected by Alovudine based on RNA-seq studies. WB:WBGene00014907 fbxa-117 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; paraquat; and Chlorpyrifos based on RNA-seq and microarray studies. WB:WBGene00014908 Y51A2B.t2 No description available WB:WBGene00014909 Y51B9A.2 Is affected by adr-1; daf-2; and sin-3 based on RNA-seq and microarray studies. WB:WBGene00014910 Y51B9A.t1 Is affected by metformin and Sirolimus based on RNA-seq studies. WB:WBGene00014911 Y51H4A.t1 No description available WB:WBGene00014912 Y51H4A.t7 No description available WB:WBGene00014914 Y52B11A.11 Enriched in ABplpppppp; ABprpppppp; AVG; RIM; and command interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and daf-18 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014915 Y53C10A.1 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including manganese chloride; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014916 fbxa-124 Enriched in germ line and neurons based on RNA-seq and microarray studies. Is affected by several genes including sir-2.1; clk-1; and dcr-1 based on microarray and RNA-seq studies. Is affected by five chemicals including stavudine; paraquat; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00014917 fbxa-122 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and fog-2 based on RNA-seq and microarray studies. Is affected by five chemicals including manganese chloride; paraquat; and Quercetin based on RNA-seq and microarray studies. WB:WBGene00014918 fbxa-123 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00014920 Y53F4B.38 Is affected by several genes including hpl-2; mut-16; and smg-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube and Doxycycline based on RNA-seq studies. WB:WBGene00014921 Y54E5B.5 Is affected by clk-1 based on microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00014922 Y57G11B.4 Is affected by several genes including ain-1; let-418; and dcp-66 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00014923 Y57G11C.26 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00014924 Y57G11C.28 Predicted to be located in membrane. WB:WBGene00014925 Y57G11C.29 Is affected by ints-5 and flcn-1 based on RNA-seq and microarray studies. WB:WBGene00014926 Y57G11C.30 Predicted to be located in membrane. WB:WBGene00014927 Y59A8A.6 No description available WB:WBGene00014928 Y59A8B.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014929 Y59A8B.t2 No description available WB:WBGene00014930 Y59A8B.t4 Is affected by alg-1 based on RNA-seq studies. WB:WBGene00014931 Y59A8B.t5 No description available WB:WBGene00014932 Y59A8B.t6 No description available WB:WBGene00014933 Y60A3A.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; unc-30; and glh-1 based on RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00014934 Y60A3A.17 Is affected by hmg-3; camt-1; and etr-1 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00014935 Y60A3A.t1 No description available WB:WBGene00014936 Y60A3A.t2 No description available WB:WBGene00014937 Y61B8A.3 No description available WB:WBGene00014938 mdt-9 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in protein transport and small GTPase mediated signal transduction. Is an ortholog of human RABIF (RAB interacting factor). WB:WBGene00014939 Y66A7A.t1 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00014940 Y67H2A.3 No description available WB:WBGene00014941 Y67H2A.9 Enriched in AWB; PVN; SAA; intestine; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; D-glucopyranose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00014943 Y68A4A.8 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00014944 Y68A4A.12 Is affected by several genes including eat-2; clk-1; and hpl-2 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Colistin; and 2 based on RNA-seq and microarray studies. WB:WBGene00014945 Y69H2.t1 No description available WB:WBGene00014946 Y70G10A.1 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including 1-methylnicotinamide; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00014947 Y71A12B.14 Enriched in AVK and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. WB:WBGene00014948 Y73F8A.4 Is affected by clk-1 based on microarray studies. WB:WBGene00014949 Y75B12A.1 Is affected by several genes including daf-16; glp-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by Rifampin; allantoin; and Cholestanol based on RNA-seq and microarray studies. WB:WBGene00014950 Y76A2B.t1 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00014951 Y76A2B.t2 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00014952 Y80D3A.t1 No description available WB:WBGene00014953 Y81G3A.2 Predicted to be located in membrane. WB:WBGene00014954 Y102A5C.5 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Alovudine; metformin; and allantoin based on RNA-seq studies. WB:WBGene00014955 Y102A5C.6 Enriched in I5 neuron; cholinergic neurons; germ line; retrovesicular ganglion; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including daf-2; gld-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00014956 Y102A5C.11 Is affected by several genes including pqm-1; hpl-2; and etr-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Alovudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014957 Y102A5C.30 Is affected by clk-1 and qui-1 based on microarray and RNA-seq studies. WB:WBGene00014958 Y105C5A.2 Is affected by several genes including skn-1; glp-1; and sek-1 based on RNA-seq studies. Is affected by metformin and Sirolimus based on RNA-seq studies. WB:WBGene00014961 Y105C5A.19 Is affected by daf-16 and eat-2 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014962 Y105C5A.20 Is affected by daf-16 and eat-2 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014963 Y105C5A.21 Is affected by elli-1; eat-2; and ints-5 based on microarray and RNA-seq studies. WB:WBGene00014964 Y105E8B.10 Is affected by daf-16 based on RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014965 Y106G6D.5 Predicted to enable RNA binding activity and transcription termination site sequence-specific DNA binding activity. Predicted to be involved in termination of RNA polymerase II transcription. Predicted to be located in nuclear body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2S and distal spinal muscular atrophy 1. Is an ortholog of human IGHMBP2 (immunoglobulin mu DNA binding protein 2). WB:WBGene00014966 Y106G6D.t1 No description available WB:WBGene00014967 Y113G7A.2 Is affected by several genes including daf-16; eat-2; and let-418 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00014969 Y113G7A.t1 No description available WB:WBGene00014970 Y113G7A.t2 No description available WB:WBGene00014971 Y113G7A.t3 Is affected by daf-2 based on microarray studies. WB:WBGene00014972 Y113G7A.t4 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00014973 Y113G7A.t5 No description available WB:WBGene00014974 Y113G7B.t2 No description available WB:WBGene00014975 Y116A8A.10 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014976 Y116A8C.7 Enriched in XXXL and XXXR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00014977 ZC15.4 Enriched in AVK and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on RNA-seq studies. Is affected by Alovudine and resveratrol based on RNA-seq and microarray studies. WB:WBGene00014978 ZC47.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by Sodium Chloride; Cadmium Chloride; and paraquat based on RNA-seq studies. WB:WBGene00014979 ZC47.11 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Sodium Chloride; and Psoralens based on RNA-seq studies. WB:WBGene00014980 ZC84.5 Is affected by daf-2 and eat-2 based on microarray studies. Is affected by Microcystin-LR based on microarray studies. WB:WBGene00014981 ZK218.9 Is affected by ints-5 and qui-1 based on RNA-seq studies. WB:WBGene00014983 ZK228.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00014984 ZK262.12 Is affected by several genes including daf-2; adr-1; and chd-3 based on RNA-seq and microarray studies. WB:WBGene00014987 ZK637.6 Expressed in hypodermis and pharynx. WB:WBGene00014989 best-23 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00014990 ZK678.t4 No description available WB:WBGene00014991 ZK829.12 Is affected by etr-1 and qui-1 based on RNA-seq studies. WB:WBGene00014992 ZK1025.1 Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq studies. Is affected by eight chemicals including manganese chloride; Alovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00014993 ZK1037.2 Is affected by resveratrol based on microarray studies. WB:WBGene00014994 ZK1225.7 Is affected by several genes including daf-16; eat-2; and unc-30 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00014996 ZK1251.5 Enriched in AVK and in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including Ethanol; manganese chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00014997 AC7.3 Enriched in AFD and in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00014998 AH9.1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00014999 AH9.3 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalapapapa; PLM; and ciliated neurons based on tiling array; microarray; proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; Zidovudine; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015000 AH9.4 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00015001 B0025.4 Predicted to be involved in chromatin organization. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Is an ortholog of human MEAF6 (MYST/Esa1 associated factor 6). WB:WBGene00015002 B0034.1 Expressed in P5.ppal; P5.ppar; hypodermis; tail; and vulval cell. WB:WBGene00015003 B0034.2 Enriched in neurons and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including aak-2; hpl-2; and drh-3 based on tiling array; microarray; and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00015004 B0034.4 Enriched in rectal epithelial cell; rectal gland cell; sensory neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by six chemicals including antimycin; cholesterol; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00015005 B0034.5 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in XXXL and XXXR. WB:WBGene00015006 B0041.1 Enriched in M cell; coelomocyte; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by four chemicals including cholesterol; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00015007 ain-2 Involved in negative regulation of gene expression; regulation of cell fate specification; and regulation of development, heterochronic. Expressed widely. WB:WBGene00015008 lmd-2 Enriched in body wall musculature; intestine; neurons; and retrovesicular ganglion based on microarray and RNA-seq studies. Is affected by several genes including daf-12; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Doxycycline; Ketamine; and Quercetin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: LysM domain; LysM and putative peptidoglycan-binding domain-containing protein 1-4; and LysM domain superfamily. Is an ortholog of human LYSMD1 (LysM domain containing 1) and LYSMD2 (LysM domain containing 2). WB:WBGene00015009 B0041.5 Involved in regulation of lipid storage and regulation of peptide transport. Predicted to be located in membrane. Is an ortholog of human SLC35F5 (solute carrier family 35 member F5). WB:WBGene00015010 ptps-1 Enables 6-pyruvoyltetrahydropterin synthase activity and identical protein binding activity. Involved in tetrahydrobiopterin biosynthetic process. Predicted to be located in mitochondrion. Expressed in hypodermis and neurons. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia A and phenylketonuria. Is an ortholog of human PTS (6-pyruvoyltetrahydropterin synthase). WB:WBGene00015011 B0041.8 Enriched in several structures, including ABplaapaap; ABplpaappa; ABpraapaap; AFD; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and npr-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by seven chemicals including rotenone; manganese chloride; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015012 bath-20 Enriched in germ line; germline precursor cell; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; Alovudine; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00015013 btb-3 Enriched in germ line; germline precursor cell; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including elt-2; sir-2.1; and dcr-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including hydrogen sulfide; stavudine; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00015014 bath-24 Enriched in germ line; germline precursor cell; head mesodermal cell; and head neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00015015 math-1 Enriched in several structures, including ALA; NSM; RIB; amphid sheath cell; and excretory system based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; lin-15B; and hsp-6 based on microarray; tiling array; and RNA-seq studies. Is affected by multi-walled carbon nanotube and Alovudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015016 bath-14 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including sir-2.1; isp-1; and unc-30 based on microarray and RNA-seq studies. Is affected by five chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015017 B0205.1 Enriched in AFD; ASER; MSpaaaaa; germ line; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and let-60 based on microarray and RNA-seq studies. Is affected by twelve chemicals including manganese chloride; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00015018 srz-85 Predicted to be located in membrane. WB:WBGene00015019 B0205.4 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to be located in Golgi cisterna membrane. Human ortholog(s) of this gene implicated in vitamin B12 deficiency. Is an ortholog of human FUT1 (fucosyltransferase 1 (H blood group)) and FUT2 (fucosyltransferase 2). WB:WBGene00015020 B0205.5 Enriched in ABalaaaala; ABalaapaaa; NSM; and body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including mex-3; hpl-2; and drh-3 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015021 nfs-1 Predicted to enable cysteine desulfurase activity. Predicted to be involved in iron-sulfur cluster assembly. Predicted to be located in cytosol; mitochondrion; and nucleus. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 52. Is an ortholog of human NFS1 (NFS1 cysteine desulfurase). WB:WBGene00015022 B0205.8 Predicted to enable RNA binding activity. Predicted to be involved in RNA 5'-cap (guanine-N7)-methylation. Predicted to be located in nucleus. Predicted to be part of mRNA cap binding activity complex. WB:WBGene00015023 B0205.9 Enriched in ABalpapppa; ABarapappa; PVR; germ line; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including Zidovudine; antimycin; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00015024 B0205.10 Enriched in germ line; hypodermis; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-seven chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq; microarray; and proteomic studies. WB:WBGene00015025 mrpl-9 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human MRPL9 (mitochondrial ribosomal protein L9). WB:WBGene00015026 B0207.1 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00015027 B0207.2 Predicted to be located in membrane. WB:WBGene00015028 B0207.5 Expressed in vas deferens valve cell. WB:WBGene00015029 B0207.6 Predicted to enable GTPase activity. Is an ortholog of human GPN2 (GPN-loop GTPase 2). WB:WBGene00015030 B0207.7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Expressed in AIYL and AIYR. WB:WBGene00015032 B0207.9 Predicted to be located in membrane. WB:WBGene00015033 B0207.10 Predicted to be located in membrane. WB:WBGene00015034 B0207.11 Enriched in germ line and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; D-glucose; and metformin based on microarray and RNA-seq studies. WB:WBGene00015035 otpl-1 Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1); OTOP2 (otopetrin 2); and OTOP3 (otopetrin 3). WB:WBGene00015036 sre-5 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00015037 B0212.3 Enriched in several structures, including Z1.p; germ line; male distal tip cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; rotenone; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00015038 nstp-6 Predicted to enable UDP-galactose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport and carbohydrate transport. Predicted to be located in Golgi membrane. WB:WBGene00015039 B0213.1 No description available WB:WBGene00015040 cyp-34A5 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and rhinitis. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2F1 (cytochrome P450 family 2 subfamily F member 1); and CYP2S1 (cytochrome P450 family 2 subfamily S member 1). WB:WBGene00015041 cyp-34A6 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and rhinitis. Is an ortholog of human CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2S1 (cytochrome P450 family 2 subfamily S member 1); and CYP2W1 (cytochrome P450 family 2 subfamily W member 1). WB:WBGene00015042 cyp-34A7 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and rhinitis. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2F1 (cytochrome P450 family 2 subfamily F member 1); and CYP2S1 (cytochrome P450 family 2 subfamily S member 1). WB:WBGene00015043 cyp-34A8 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). WB:WBGene00015044 cyp-34A9 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). WB:WBGene00015045 cyp-34A10 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). WB:WBGene00015046 nlp-34 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00015047 faah-1 Predicted to enable amidase activity and fatty acid amide hydrolase activity. Involved in positive regulation of axon regeneration. Expressed in pharyngeal neurons and pharynx. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Is an ortholog of human FAAH (fatty acid amide hydrolase). WB:WBGene00015048 faah-2 Predicted to enable amidase activity and fatty acid amide hydrolase activity. Predicted to be involved in fatty acid catabolic process. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Is an ortholog of human FAAH (fatty acid amide hydrolase). WB:WBGene00015049 B0218.5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00015050 clec-51 Predicted to enable signaling receptor activity. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and liver cirrhosis. Is an ortholog of several human genes including LY75 (lymphocyte antigen 75); MRC2 (mannose receptor C type 2); and REG3A (regenerating family member 3 alpha). WB:WBGene00015051 B0218.7 Enriched in amphid sheath cell; germ line; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-seven chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00015052 clec-52 Predicted to enable signaling receptor activity. Involved in defense response to Gram-positive bacterium. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and liver cirrhosis. Is an ortholog of several human genes including LY75 (lymphocyte antigen 75); MRC2 (mannose receptor C type 2); and REG3A (regenerating family member 3 alpha). WB:WBGene00015053 B0222.1 Predicted to be located in membrane. WB:WBGene00015054 pitr-2 Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Is an ortholog of human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2). WB:WBGene00015055 pitr-3 Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Is an ortholog of human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2). WB:WBGene00015056 B0222.5 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00015057 gad-3 Predicted to enable oxidoreductase activity. Involved in IRE1-mediated unfolded protein response. WB:WBGene00015058 B0222.10 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABplpapapa; RIC; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and let-7 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00015059 B0228.1 Enriched in several structures, including ABalppppaa; ABplpaaaaa; ABplpaaaap; head ganglion; and interfacial epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015061 cpna-2 Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in nucleus. Expressed in body wall musculature; muscle cell; and pharyngeal muscle cell. WB:WBGene00015062 trx-1 Enables protein-disulfide reductase activity. Involved in determination of adult lifespan. Located in several cellular components, including neuronal cell body; nucleus; and plasma membrane bounded cell projection. Expressed in ASJL; ASJR; head neurons; and in male. WB:WBGene00015063 B0228.6 Predicted to be located in membrane. WB:WBGene00015064 B0228.7 Predicted to enable S-methyl-5-thioadenosine phosphorylase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytosol. Expressed in Ea and Ep. Human ortholog(s) of this gene implicated in common bile duct neoplasm; diaphyseal medullary stenosis with malignant fibrous histiocytoma; and pancreatic cancer. Is an ortholog of human MTAP (methylthioadenosine phosphorylase). WB:WBGene00015065 B0228.8 Enriched in neurons and in male based on RNA-seq and microarray studies. Is affected by several genes including let-60; csr-1; and set-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Zidovudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: Family of unknown function (DUF5382) and Protein of unknown function DUF5382. WB:WBGene00015066 B0228.9 Enriched in ASK and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including clk-1; prg-1; and set-2 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: Family of unknown function (DUF5382) and Protein of unknown function DUF5382. WB:WBGene00015067 cest-35.1 Predicted to enable carboxylic ester hydrolase activity. Is an ortholog of human CES2 (carboxylesterase 2); CES3 (carboxylesterase 3); and CES5A (carboxylesterase 5A). WB:WBGene00015068 srt-68 Predicted to be located in membrane. Expressed in head neurons. WB:WBGene00015069 srt-67 Predicted to be located in membrane. WB:WBGene00015070 srt-70 Predicted to be located in membrane. Expressed in ADFL; ADFR; PHBL; and PHBR. WB:WBGene00015071 cest-30 Predicted to enable carboxylic ester hydrolase activity. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). WB:WBGene00015072 srt-69 Predicted to be located in membrane. WB:WBGene00015073 B0238.9 Enriched in several structures, including XXX cell; germ line; germline precursor cell; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Ethanol; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Headcase protein and Headcase protein family homologue. WB:WBGene00015074 natc-2 Predicted to enable peptide alpha-N-acetyltransferase activity. Involved in dauer larval development. Predicted to be part of NatC complex. Is an ortholog of human NAA30 (N-alpha-acetyltransferase 30, NatC catalytic subunit). WB:WBGene00015075 penr-1 Enriched in body wall muscle cell; germ line; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and daf-12 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: High mobility group box domain superfamily and Phosphorylation site. WB:WBGene00015076 B0238.12 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00015077 B0238.13 Is affected by several genes including daf-16; daf-2; and hsf-1 based on proteomic; microarray; and RNA-seq studies. Is affected by thirteen chemicals including tryptophan; tert-Butylhydroperoxide; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00015078 srt-66 Is affected by daf-12 based on microarray studies. Is affected by tetrabromobisphenol A based on microarray studies. WB:WBGene00015079 B0244.4 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00015080 B0244.5 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00015081 B0244.6 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00015082 B0244.7 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00015083 egg-1 Predicted to enable signaling receptor activity. Involved in positive regulation of protein localization to cell periphery and sexual reproduction. Located in plasma membrane. Expressed in germ line. WB:WBGene00015084 B0244.9 Predicted to be located in membrane. WB:WBGene00015085 B0244.10 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00015087 B0252.1 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. WB:WBGene00015088 B0252.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Is an ortholog of several human genes including SLC22A11 (solute carrier family 22 member 11); SLC22A14 (solute carrier family 22 member 14); and SLC22A4 (solute carrier family 22 member 4). WB:WBGene00015089 B0252.5 Enriched in IL2 neuron; germ line; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including manganese chloride; D-glucose; and Alovudine based on RNA-seq; microarray; and proteomic studies. WB:WBGene00015091 vep-1 Predicted to enable TFIIIC-class transcription factor complex binding activity. Predicted to be involved in RNA polymerase III preinitiation complex assembly. Predicted to be part of transcription factor TFIIIB complex. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 112. Is an ortholog of human BDP1 (B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB). WB:WBGene00015092 mrpl-47 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrial ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL47 (mitochondrial ribosomal protein L47). WB:WBGene00015093 B0261.5 Predicted to be located in membrane. WB:WBGene00015094 B0261.6 Enriched in amphid sheath cell; germ line; sperm; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-seven chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq; microarray; and proteomic studies. WB:WBGene00015095 B0261.7 Enriched in several structures, including germ line; germline precursor cell; head mesodermal cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including manganese chloride; Zidovudine; and metformin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015096 B0261.8 Enriched in intestinal muscle; rectal muscle; sensory neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by mianserin and paraquat based on RNA-seq studies. WB:WBGene00015097 B0273.1 Enriched in DD neuron; RID; germ line; muscle cell; and in male based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray; RNA-seq; and proteomic studies. WB:WBGene00015098 snpc-3.1 Predicted to enable RNA polymerase III type 3 promoter sequence-specific DNA binding activity and bent DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and core promoter sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of snRNA-activating protein complex. Is an ortholog of human SNAPC3 (small nuclear RNA activating complex polypeptide 3). WB:WBGene00015099 ggtb-1 Predicted to enable small GTPase binding activity and zinc ion binding activity. Predicted to contribute to Rab geranylgeranyltransferase activity. Involved in PERK-mediated unfolded protein response. Predicted to be part of Rab-protein geranylgeranyltransferase complex. Expressed in head; intestine; and tail. Is an ortholog of human RABGGTB (Rab geranylgeranyltransferase subunit beta). WB:WBGene00015100 B0280.2 Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be located in cytoplasm. WB:WBGene00015101 rpia-1 Predicted to enable ribose-5-phosphate isomerase activity. Predicted to be involved in D-ribose metabolic process and pentose-phosphate shunt, non-oxidative branch. Expressed in head neurons; intestine; nerve ring; and tail neurons. Is an ortholog of human RPIA (ribose 5-phosphate isomerase A). WB:WBGene00015102 cpg-2 Enables chitin binding activity. Involved in several processes, including eggshell formation; mitotic cytokinesis; and regulation of cytokinesis. Located in external encapsulating structure and perivitelline space. Expressed in eggshell. WB:WBGene00015103 B0280.7 Expressed in g1AL; g1AR; g1P; g2L; and g2R. WB:WBGene00015104 B0280.9 Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Is an ortholog of human UTP18 (UTP18 small subunit processome component). WB:WBGene00015105 pot-1 Enables C-rich strand telomeric DNA binding activity. Involved in negative regulation of telomere maintenance via telomere lengthening and telomere maintenance. Located in chromosome, telomeric region. WB:WBGene00015106 B0280.11 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00015107 viro-2 Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be located in cytoplasm. Expressed in intestinal cell and somatic cell. WB:WBGene00015108 B0281.1 Enriched in AFD based on RNA-seq studies. Is affected by several genes including skn-1; clk-1; and nhr-49 based on microarray and RNA-seq studies. Is affected by paraquat; bortezomib; and Atrazine based on RNA-seq and microarray studies. WB:WBGene00015109 B0281.2 No description available WB:WBGene00015110 B0281.3 Predicted to enable zinc ion binding activity. Is an ortholog of human TRIM59 (tripartite motif containing 59). WB:WBGene00015111 B0281.4 Predicted to be located in motile cilium. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00015112 B0281.5 Involved in monoatomic ion transport and protein folding. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00015113 B0281.6 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00015114 trim-21 Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm. Expressed in several structures, including pharyngeal muscle cell and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; Sweet syndrome; and hematologic cancer (multiple). Is an ortholog of several human genes including MEFV (MEFV innate immunity regulator, pyrin); TRIM21 (tripartite motif containing 21); and TRIM27 (tripartite motif containing 27). WB:WBGene00015115 B0286.1 Enriched in several structures, including ABaraappaa; distal tip cell; head mesodermal cell; neurons; and pharyngeal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including 1-methylnicotinamide; rotenone; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015116 paic-1 Enables identical protein binding activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase). WB:WBGene00015117 B0294.1 Enriched in several structures, including ABalppppaa; ABalppppppa; AVE; amphid neurons; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including 1-methylnicotinamide; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015118 B0294.3 Enriched in body wall muscle cell; hypodermis; neurons; and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including clk-1; kri-1; and set-2 based on tiling array; microarray; and RNA-seq studies. Is affected by Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily and F-box domain. WB:WBGene00015119 B0302.2 Enriched in AVK and neurons based on RNA-seq studies. Is affected by several genes including elt-2; pgl-1; and mex-1 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015120 B0302.3 No description available WB:WBGene00015121 B0302.4 Enriched in AVK based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by dibromoacetic acid based on microarray studies. WB:WBGene00015122 B0302.5 Enriched in several structures, including anterior ganglion; anterior hypodermis; head mesodermal cell; interfacial epithelial cell; and pm6 based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00015123 B0302.6 No description available WB:WBGene00015124 anmt-1 Predicted to enable N-methyltransferase activity. Predicted to be involved in methylation. Located in striated muscle dense body and striated muscle myosin thick filament. Human ortholog(s) of this gene implicated in renal cell carcinoma. Is an ortholog of human NNMT (nicotinamide N-methyltransferase). WB:WBGene00015125 hadb-1 Predicted to enable acetyl-CoA C-acyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Located in mitochondrion. Expressed in tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; mitochondrial metabolism disease; and mitochondrial trifunctional protein deficiency. Is an ortholog of human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta). WB:WBGene00015126 B0303.4 Predicted to be involved in ubiquitin-dependent ERAD pathway. Is an ortholog of human TMUB1 (transmembrane and ubiquitin like domain containing 1) and TMUB2 (transmembrane and ubiquitin like domain containing 2). WB:WBGene00015127 B0303.5 No description available WB:WBGene00015128 B0303.7 Predicted to be involved in actin filament organization and cell migration. Is an ortholog of human SH3D19 (SH3 domain containing 19). WB:WBGene00015129 sdz-1 Involved in mesendoderm development. Expressed in several structures, including E; Ea; Ep; MSpa; and somatic gonad precursor. WB:WBGene00015130 vps-33.1 Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in lysosome. Predicted to be part of CORVET complex and HOPS complex. Expressed in several structures, including body wall musculature; hypodermis; intestine; pharynx; and spermatheca. Is an ortholog of human VPS33A (VPS33A core subunit of CORVET and HOPS complexes). WB:WBGene00015131 B0303.11 Predicted to enable chloride:monoatomic cation symporter activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in membrane. Expressed in excretory duct cell. WB:WBGene00015132 B0303.14 Enriched in several structures, including Z1.p; Z4.a; intestine; male distal tip cell; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Alovudine; allantoin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015133 mrpl-11 Predicted to enable large ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL11 (mitochondrial ribosomal protein L11). WB:WBGene00015134 B0304.2 Enriched in several structures, including BAG; cephalic sheath cell; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and elt-2 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00015135 cyp-23A1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00015136 B0304.4 Enriched in germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; Zidovudine; and metformin based on microarray and RNA-seq studies. WB:WBGene00015137 B0310.1 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00015138 B0310.2 Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. WB:WBGene00015139 B0310.3 Predicted to be located in membrane. WB:WBGene00015141 ugt-46 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of several human genes including UGT3A1 (UDP glycosyltransferase family 3 member A1); UGT3A2 (UDP glycosyltransferase family 3 member A2); and UGT8 (UDP glycosyltransferase 8). WB:WBGene00015142 B0310.6 Enriched in MSaapaapa; MSpapaapa; g2; rectal epithelial cell; and touch receptor neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including 1-methylnicotinamide; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00015143 rbm-26 Predicted to enable RNA binding activity. Predicted to be involved in mRNA processing. Predicted to be located in nucleus. Expressed in gonad; neurons; and tail. Is an ortholog of human RBM27 (RNA binding motif protein 27). WB:WBGene00015145 arle-14 Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human ARL14EP (ADP ribosylation factor like GTPase 14 effector protein) and ARL14EPL (ADP ribosylation factor like GTPase 14 effector protein like). WB:WBGene00015146 abi-1 Enables SH3 domain binding activity and protein kinase binding activity. Involved in several processes, including positive regulation of endocytosis; presynaptic actin cytoskeleton organization; and synaptic vesicle clustering. Located in axon; cytoplasm; and somatodendritic compartment. Expressed in coelomocyte; head neurons; and ventral cord neurons. Is an ortholog of human ABI1 (abl interactor 1). WB:WBGene00015147 B0336.7 Predicted to enable DNA binding activity. Expressed in intestine and neurons. WB:WBGene00015148 hpo-28 Predicted to be located in endomembrane system and endoplasmic reticulum-endosome membrane contact site. Is an ortholog of human MOSPD2 (motile sperm domain containing 2). WB:WBGene00015149 B0336.12 Enriched in AVA based on tiling array studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015150 B0336.13 Predicted to enable RNA polymerase II general transcription initiation factor activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIA complex. Is an ortholog of human GTF2A2 (general transcription factor IIA subunit 2). WB:WBGene00015151 B0348.1 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00015152 B0348.2 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00015153 idpp-2 Enriched in DVA; intestine; pharyngeal-intestinal valve; and pm6 based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Sirolimus; and antimycin based on RNA-seq and microarray studies. WB:WBGene00015155 B0353.1 Enriched in several structures, including interfacial epithelial cell; intestine; pharyngeal muscle cell; sensory neurons; and spermatheca based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and clk-1 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015156 cwf-19L2 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of post-mRNA release spliceosomal complex. Is an ortholog of human CWF19L2 (CWF19 like cell cycle control factor 2). WB:WBGene00015157 B0361.3 Enriched in several structures, including MSaaaaapa; MSpppaaa; germ line; head mesodermal cell; and pharyngeal gland cell based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq; microarray; and proteomic studies. Is affected by seven chemicals including rotenone; Zidovudine; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015158 B0361.4 Predicted to enable heme binding activity and oxygen binding activity. WB:WBGene00015159 psd-1 Predicted to enable phosphatidylserine decarboxylase activity. Predicted to be involved in lipid droplet formation and phosphatidylethanolamine biosynthetic process. Predicted to be located in lipid droplet and mitochondrion. Is an ortholog of human PISD (phosphatidylserine decarboxylase). WB:WBGene00015160 spot-1 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human SPOUT1 (SPOUT domain containing methyltransferase 1). WB:WBGene00015161 pho-5 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J and prostate cancer. Is an ortholog of human ACP2 (acid phosphatase 2, lysosomal); ACP3 (acid phosphatase 3); and ACP4 (acid phosphatase 4). WB:WBGene00015162 algn-11 Predicted to enable GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ip. Is an ortholog of human ALG11 (ALG11 alpha-1,2-mannosyltransferase). WB:WBGene00015163 B0361.9 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00015164 ykt-6 Predicted to enable SNAP receptor activity and protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; vesicle docking involved in exocytosis; and vesicle targeting. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Is an ortholog of human YKT6 (YKT6 v-SNARE homolog). WB:WBGene00015165 B0361.11 Predicted to enable transmembrane transporter activity. Predicted to be involved in carbohydrate transport and transmembrane transport. Predicted to be located in membrane. WB:WBGene00015166 B0403.1 No description available WB:WBGene00015167 B0403.3 Predicted to be located in extracellular region. WB:WBGene00015168 pdi-6 Predicted to enable protein-disulfide reductase activity. Involved in negative regulation of IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum lumen. Expressed in head; intestinal muscle; and tail. Is an ortholog of human PDIA6 (protein disulfide isomerase family A member 6). WB:WBGene00015169 B0403.5 Enriched in hypodermis; interfacial epithelial cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by fourteen chemicals including D-glucose; 4-bromodiphenyl ether; and stavudine based on RNA-seq and microarray studies. WB:WBGene00015170 B0410.1 Enriched in ABalaaaarl and ABalaaaarr based on single-cell RNA-seq studies. Is affected by several genes including pgl-1; mex-1; and glh-1 based on tiling array and RNA-seq studies. Is affected by five chemicals including Rifampin; Sirolimus; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015171 vang-1 Enables PDZ domain binding activity. Involved in Wnt signaling pathway, planar cell polarity pathway and digestive tract morphogenesis. Located in apical plasma membrane and basolateral plasma membrane. Expressed in several structures, including P5.ppp; P7.paa; egg-laying apparatus; gonad; and neurons. Human ortholog(s) of this gene implicated in caudal regression syndrome and neural tube defect. Is an ortholog of human VANGL1 (VANGL planar cell polarity protein 1) and VANGL2 (VANGL planar cell polarity protein 2). WB:WBGene00015172 B0410.3 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00015173 trpp-11 Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2S. Is an ortholog of human TRAPPC11 (trafficking protein particle complex subunit 11). WB:WBGene00015175 srz-4 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00015176 vps-51 Enables syntaxin binding activity. Involved in negative regulation of dense core granule transport; positive regulation of dense core granule transport; and positive regulation of locomotion involved in locomotory behavior. Part of GARP complex. Expressed in body wall musculature; intestinal cell; and neurons. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 13. Is an ortholog of human VPS51 (VPS51 subunit of GARP complex). WB:WBGene00015177 tmc-2 Predicted to enable mechanosensitive monoatomic ion channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in plasma membrane. Expressed in body wall musculature and vulval muscle. Is an ortholog of human TMC3 (transmembrane channel like 3). WB:WBGene00015178 B0416.2 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including tryptophan; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Cystine-knot cytokine. WB:WBGene00015179 B0416.3 Predicted to be located in membrane. WB:WBGene00015180 B0416.4 Predicted to enable metal ion binding activity. WB:WBGene00015181 B0416.5 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in gonad. Is an ortholog of human SLC49A3 (solute carrier family 49 member 3). WB:WBGene00015182 B0416.7 Enriched in IL socket cell; germ line; hypodermis; muscle cell; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00015183 B0432.1 Predicted to be located in membrane. WB:WBGene00015184 djr-1.1 Predicted to enable glyoxalase III activity. Involved in several processes, including cellular aldehyde metabolic process; cellular response to aldehyde; and monocarboxylic acid biosynthetic process. Located in cytoplasm and nucleus. Expressed in intestine. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease 7; Parkinsonism; and middle cerebral artery infarction. Is an ortholog of human PARK7 (Parkinsonism associated deglycase). WB:WBGene00015185 mrpl-41 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL41 (mitochondrial ribosomal protein L41). WB:WBGene00015186 misc-1 Predicted to enable transmembrane transporter activity. Predicted to be involved in C4-dicarboxylate transport and inorganic anion transport. Located in mitochondrion. Expressed in several structures, including intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in paraganglioma. Is an ortholog of human SLC25A11 (solute carrier family 25 member 11). WB:WBGene00015188 B0432.7 Enriched in several structures, including ABaraapapaa; AFD; germ line; male distal tip cell; and pharyngeal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. Human CIP2A enables protein homodimerization activity. Is predicted to encode a protein with the following domains: Protein CIP2A; Armadillo-type fold; and Phosphorylation site. Is an ortholog of human CIP2A (cellular inhibitor of PP2A). WB:WBGene00015189 B0432.8 Predicted to enable hydrolase activity, acting on ester bonds. Is an ortholog of human TATDN3 (TatD DNase domain containing 3). WB:WBGene00015190 B0432.9 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; NSM; and male distal tip cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and unc-30 based on RNA-seq and microarray studies. Is affected by stavudine and antimycin based on RNA-seq studies. Human MBLAC1 enables RNA endonuclease activity and metal ion binding activity. Is predicted to encode a protein with the following domains: Metallo-beta-lactamase; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; Metallo-beta-lactamase domain-containing protein 1; and Metallo-beta-lactamase superfamily. Is an ortholog of human MBLAC1 (metallo-beta-lactamase domain containing 1). WB:WBGene00015191 B0432.10 Enriched in several structures, including ABalaaaala; ABalaapaaa; AFD; germ line; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and lin-35 based on microarray and RNA-seq studies. Is affected by eight chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015192 B0432.11 Predicted to be located in membrane. WB:WBGene00015193 clec-117 Enriched in amphid sheath cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by seventeen chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00015194 trul-1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and replication fork processing. Predicted to be located in nucleus and site of DNA damage. Human ortholog(s) of this gene implicated in Seckel syndrome 9. Is an ortholog of human TRAIP (TRAF interacting protein). WB:WBGene00015196 B0454.5 Predicted to be located in membrane. Expressed in ventral cord blast cell. WB:WBGene00015197 B0454.6 Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in amino acid transport. Predicted to be located in plasma membrane. Is an ortholog of human SLC7A4 (solute carrier family 7 member 4). WB:WBGene00015198 clec-2 Is affected by several genes including skn-1; age-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including methylmercuric chloride; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00015199 B0454.8 Enriched in germline precursor cell; hypodermis; and tail hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercury hydroxide; Tunicamycin; and cholesterol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00015200 lido-13 Predicted to be located in nucleus. WB:WBGene00015201 B0478.2 No description available WB:WBGene00015202 B0478.3 Predicted to enable phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion and phospholipid metabolic process. Predicted to be located in membrane. WB:WBGene00015203 cdk-11.1 Predicted to enable protein serine/threonine kinase activity. Involved in gamete generation and positive regulation of embryonic development. Located in cytoplasm and nucleus. Expressed in gonadal sheath cell; somatic cell; and somatic gonad. Is an ortholog of human CDK11A (cyclin dependent kinase 11A) and CDK11B (cyclin dependent kinase 11B). WB:WBGene00015204 B0495.5 Predicted to be involved in carbohydrate metabolic process. Is an ortholog of human SPATA20 (spermatogenesis associated 20). WB:WBGene00015205 moa-2 Enriched in germ line; muscle cell; neurons; retrovesicular ganglion; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq; tiling array; and microarray studies. Is affected by six chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015206 B0495.7 Predicted to enable metal ion binding activity and metalloexopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in endoplasmic reticulum membrane. Expressed in several structures, including AB and Psub1. Is an ortholog of human ERMP1 (endoplasmic reticulum metallopeptidase 1). WB:WBGene00015207 luc-7L Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to be part of U1 snRNP and U2-type prespliceosome. Is an ortholog of human LUC7L (LUC7 like). WB:WBGene00015208 B0495.9 Predicted to be located in membrane. Expressed in pharyngeal muscle cell. WB:WBGene00015210 B0496.1 Enriched in Z1 and Z4 based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00015211 B0496.2 Enriched in AFD; germ line; intestine; and in male based on RNA-seq and microarray studies. Is affected by several genes including sir-2.1; pmk-1; and nhr-49 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00015214 srtx-1 Involved in thermosensory behavior. Located in neuron projection membrane and neuron projection terminus. Expressed in AFDL; AFDR; AWCL; and AWCR. WB:WBGene00015215 B0496.6 Predicted to be located in membrane. WB:WBGene00015216 valv-1 Predicted to enable zinc ion binding activity. Involved in digestive system process and egg-laying behavior. Predicted to be located in cytoplasm. Is an ortholog of human CRIP1 (cysteine rich protein 1). WB:WBGene00015217 tes-1 Predicted to enable zinc ion binding activity. Predicted to be located in cytoplasm. Expressed in AB. Human ortholog(s) of this gene implicated in coronary stenosis. Is an ortholog of human LMCD1 (LIM and cysteine rich domains 1) and TES (testin LIM domain protein). WB:WBGene00015218 B0507.1 Involved in pharyngeal gland morphogenesis. Expressed in hermaphrodite distal tip cell; pharyngeal gland cell; pharyngeal-intestinal valve; rectal gland cell; and spermatheca. WB:WBGene00015219 B0507.2 Enriched in MSpppaaa; coelomocyte; head mesodermal cell; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; proteomic; RNA-seq; and tiling array studies. Is affected by ten chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BRO1 domain; BRO1-like domain; BRO1 domain superfamily; and BRO1 domain-containing protein BROX. Is an ortholog of human BROX (BRO1 domain and CAAX motif containing). WB:WBGene00015220 B0507.3 Enriched in several structures, including ABplpappaa; BDU; head mesodermal cell; mechanosensory neurons; and pharyngeal muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; levamisole; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015221 B0507.4 Enriched in ALM; PLM; and neurons based on microarray and RNA-seq studies. Is affected by several genes including eat-2; clk-1; and lin-15B based on microarray and RNA-seq studies. Is affected by bortezomib based on RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF713) and Protein of unknown function DUF713. WB:WBGene00015222 B0507.5 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; lin-15B; and prg-1 based on microarray; tiling array; and RNA-seq studies. Is affected by aldicarb; Rifampin; and bortezomib based on microarray and RNA-seq studies. WB:WBGene00015223 B0507.6 Enriched in body wall muscle cell; cephalic sheath cell; dopaminergic neurons; intestine; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF713) and Protein of unknown function DUF713. WB:WBGene00015224 B0507.7 Enriched in several structures, including ABalaaaala; ABalaapaaa; coelomocyte; germ line; and muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00015225 B0507.8 Enriched in body wall muscle cell; cephalic sheath cell; excretory cell; intestine; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Nitric Oxide; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. WB:WBGene00015226 B0507.9 Enriched in BDU; excretory cell; and neurons based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Mercuric Chloride; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00015227 ddn-1 Expressed in AFD; M5 neuron; body wall musculature; and chemosensory neurons. WB:WBGene00015228 B0511.2 Enriched in several structures, including germ line; head motor neurons; intestine; mechanosensory neurons; and pharyngeal muscle cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and clk-1 based on microarray; RNA-seq; and proteomic studies. Is affected by Doxycycline; resveratrol; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015229 fbxa-125 Enriched in germ line; hypodermis; and in male based on RNA-seq studies. Is affected by several genes including daf-2; pie-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00015230 tag-344 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cellular response to glucose starvation; intracellular signal transduction; and negative regulation of TOR signaling. Predicted to be part of nucleotide-activated protein kinase complex. Is an ortholog of several human genes including TSSK1B (testis specific serine kinase 1B); TSSK2 (testis specific serine kinase 2); and TSSK3 (testis specific serine kinase 3). WB:WBGene00015231 cutl-14 Enriched in several structures, including germline precursor cell; hypodermis; male distal tip cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; Mercuric Chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Zona pellucida-like domain and Zona pellucida domain. WB:WBGene00015232 B0511.6 Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Expressed in head and tail. Is an ortholog of human DDX18 (DEAD-box helicase 18). WB:WBGene00015233 sut-6 Predicted to enable mRNA binding activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be involved in negative regulation of protein dephosphorylation. Predicted to be located in nuclear speck. Is an ortholog of human PPP1R8 (protein phosphatase 1 regulatory subunit 8). WB:WBGene00015235 cdc-26 Predicted to be involved in cell division; meiotic cell cycle; and protein ubiquitination. Predicted to be located in nucleus. Expressed in germ line. WB:WBGene00015236 B0511.11 Enriched in several structures, including AVA; germ line; nerve ring neurons; rectal epithelial cell; and rectum based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including nicotinic acid; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015237 B0511.12 Predicted to be involved in endoplasmic reticulum organization. Predicted to be located in endoplasmic reticulum. Is an ortholog of human PCNX2 (pecanex 2) and PCNX3 (pecanex 3). WB:WBGene00015238 mppe-1 Predicted to enable hydrolase activity and metal ion binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in Golgi apparatus and endoplasmic reticulum-Golgi intermediate compartment membrane. Is an ortholog of human MPPE1 (metallophosphoesterase 1). WB:WBGene00015241 B0524.2 Predicted to enable triglyceride lipase activity. Predicted to be involved in lipid homeostasis and triglyceride catabolic process. Predicted to be located in cytoplasm; lipid droplet; and membrane. Is an ortholog of human PNPLA4 (patatin like phospholipase domain containing 4). WB:WBGene00015242 B0524.3 Enriched in germ line based on RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and unc-30 based on tiling array; RNA-seq; and microarray studies. Is affected by Doxycycline; paraquat; and resveratrol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function and Domain of unknown function WSN. WB:WBGene00015243 B0524.4 Enriched in germ line; intestine; and seam cell based on RNA-seq studies. Is affected by several genes including daf-2; let-60; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including methylmercuric chloride; Tunicamycin; and antimycin based on microarray and RNA-seq studies. WB:WBGene00015244 B0524.5 Enriched in I5 neuron; cholinergic neurons; germ line; retrovesicular ganglion; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and pmk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; mianserin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00015245 B0524.6 Enriched in AFD; body wall muscle cell; germ line; and germline precursor cell based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; Zidovudine; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015246 scl-23 Predicted to be located in extracellular space. WB:WBGene00015247 B0545.4 Predicted to enable protein dimerization activity. WB:WBGene00015248 mai-2 Enables ATPase inhibitor activity. Predicted to be involved in heme biosynthetic process. Located in mitochondrion. Expressed in germ line and tail. Is an ortholog of human ATP5IF1 (ATP synthase inhibitory factor subunit 1). WB:WBGene00015249 otub-4 Predicted to enable K63-linked deubiquitinase activity and cysteine-type deubiquitinase activity. Is an ortholog of human OTUD5 (OTU deubiquitinase 5). WB:WBGene00015250 B0546.3 Predicted to enable metal ion binding activity. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human YPEL5 (yippee like 5). WB:WBGene00015251 B0546.4 Predicted to enable metal ion binding activity. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human YPEL5 (yippee like 5). WB:WBGene00015252 B0546.5 Predicted to be located in membrane. WB:WBGene00015253 B0547.2 Is affected by several genes including daf-2; lin-4; and lin-14 based on tiling array and microarray studies. Is affected by adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00015254 B0554.1 Enriched in anterior arcade cell and pharynx based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including age-1; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00015255 B0554.2 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-2; sir-2.1; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by resveratrol; Atrazine; and cadmium based on microarray studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00015257 B0554.4 Enriched in amphid sheath cell and tail hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and glycine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00015258 B0554.5 Predicted to be located in membrane. Expressed in excretory cell. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00015259 dod-20 Enriched in DA neuron; VA neuron; head mesodermal cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including methylmercury hydroxide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00015260 B0554.7 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00015261 B0563.1 Enriched in body wall muscle cell; hypodermis; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; elt-2; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00015262 B0563.5 Enriched in ALN and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including rotenone; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00015263 B0563.6 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00015264 B0563.7 Predicted to enable calcium ion binding activity and microtubule binding activity. Predicted to be located in microtubule organizing center. Is an ortholog of human CETN1 (centrin 1). WB:WBGene00015265 B0563.8 Enriched in FLP; M cell; enteric muscle; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; Alovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00015266 BE0003N10.1 Predicted to enable 3'-5'-RNA exonuclease activity and polyribonucleotide nucleotidyltransferase activity. Predicted to be involved in mitochondrial RNA 3'-end processing and mitochondrial mRNA catabolic process. Predicted to be located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 70; combined oxidative phosphorylation deficiency 13; and spinocerebellar ataxia type 25. Is an ortholog of human PNPT1 (polyribonucleotide nucleotidyltransferase 1). WB:WBGene00015267 chin-1 Predicted to enable GTPase activator activity. Involved in protein localization. Located in cell cortex. Human ortholog(s) of this gene implicated in Duane retraction syndrome. Is an ortholog of human CHN1 (chimerin 1). WB:WBGene00015268 fbxo-11.2 Predicted to enable zinc ion binding activity. Predicted to be involved in regulation of apoptotic process and ubiquitin-dependent protein catabolic process. Human ortholog(s) of this gene implicated in breast carcinoma; gastrointestinal system cancer (multiple); and lung non-small cell carcinoma. Is an ortholog of human FBXO11 (F-box protein 11). WB:WBGene00015269 C01B4.2 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00015270 C01B4.6 Predicted to enable aldose 1-epimerase activity. Predicted to be involved in galactose catabolic process via UDP-galactose and glucose metabolic process. Human ortholog(s) of this gene implicated in galactosemia. Is an ortholog of human GALM (galactose mutarotase). WB:WBGene00015271 C01B4.7 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00015272 C01B4.8 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00015273 mct-2 Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Is an ortholog of human SLC16A4 (solute carrier family 16 member 4). WB:WBGene00015277 C01B7.7 Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by six chemicals including Tunicamycin; multi-walled carbon nanotube; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00015278 C01B10.3 Predicted to enable inositol-polyphosphate 5-phosphatase activity. Predicted to be involved in inositol phosphate-mediated signaling. Expressed in pharyngeal muscle cell and rectal epithelium. Is an ortholog of human INPP5A (inositol polyphosphate-5-phosphatase A). WB:WBGene00015279 cest-5.1 Predicted to be located in membrane. WB:WBGene00015280 C01B10.6 Enriched in several structures, including ABalaappppa; head mesodermal cell; head neurons; pharyngeal cell; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-five chemicals including Ethanol; 1-methylnicotinamide; and manganese chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00015281 C01B10.7 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including aldicarb; Tunicamycin; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00015282 C01B10.8 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Expressed in intestine. Is an ortholog of human METTL13 (methyltransferase 13, eEF1A N-terminus and K55). WB:WBGene00015283 C01B10.9 Predicted to enable bis(5'-adenosyl)-triphosphatase activity. Predicted to be located in I band and striated muscle dense body. Is an ortholog of human ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase 4). WB:WBGene00015284 cest-5.2 Predicted to be located in membrane. WB:WBGene00015285 gmeb-1 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and metal ion binding activity. Predicted to be involved in DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Is an ortholog of human GMEB1 (glucocorticoid modulatory element binding protein 1). WB:WBGene00015286 best-3 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human BEST3 (bestrophin 3). WB:WBGene00015287 osta-1 Located in periciliary membrane compartment. Expressed in amphid neurons; ciliated neurons; phasmid neurons; and sensory neurons. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Is an ortholog of human SLC51A (solute carrier family 51 subunit alpha). WB:WBGene00015288 best-4 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of human BEST1 (bestrophin 1) and BEST3 (bestrophin 3). WB:WBGene00015289 C01B12.6 No description available WB:WBGene00015291 enee-1 Enriched in several structures, including ABalaappppa; ABalapaappa; ciliated neurons; germ line; and head mesodermal cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including dpy-10; daf-12; and clk-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by ten chemicals including rotenone; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00015292 C01C4.2 Enriched in AFD; AWCL; AWCR; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Ag nanoparticles; Atrazine; and cadmium based on RNA-seq and microarray studies. WB:WBGene00015293 C01C4.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cytoplasm. Is an ortholog of human SBK1 (SH3 domain binding kinase 1). WB:WBGene00015294 C01C10.2 Enriched in hypodermis; interfacial epithelial cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including rotenone; levamisole; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015295 acl-12 Predicted to enable acyltransferase activity. Involved in IRE1-mediated unfolded protein response and PERK-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum. WB:WBGene00015296 gtf-2F1 Predicted to enable RNA polymerase II general transcription initiation factor activity and TFIIF-class transcription factor complex binding activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIF complex. Is an ortholog of human GTF2F1 (general transcription factor IIF subunit 1). WB:WBGene00015297 sco-1 Predicted to enable copper chaperone activity and copper ion binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial inner membrane. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy; mitochondrial complex IV deficiency nuclear type 2; and myopia. Is an ortholog of human SCO1 (synthesis of cytochrome C oxidase 1). WB:WBGene00015298 rml-4 Predicted to enable dTDP-glucose 4,6-dehydratase activity. Predicted to be involved in small molecule metabolic process. Expressed in hyp7 syncytium; hypodermal cell; and seam cell. Human ortholog(s) of this gene implicated in Catel Manzke syndrome. Is an ortholog of human TGDS (TDP-glucose 4,6-dehydratase). WB:WBGene00015299 npr-42 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00015300 C01F1.5 Predicted to enable metallopeptidase activity. WB:WBGene00015301 C01F1.6 Predicted to enable signaling receptor binding activity. Predicted to be involved in protein retention in ER lumen. Predicted to be located in cytoplasm. Expressed in head. Is an ortholog of human ANKRD13C (ankyrin repeat domain 13C). WB:WBGene00015303 rga-6 Involved in defense response to fungus. Used to study long QT syndrome. Is an ortholog of human ARHGAP36 (Rho GTPase activating protein 36) and ARHGAP6 (Rho GTPase activating protein 6). WB:WBGene00015305 C01G5.3 Predicted to be part of DNA-directed RNA polymerase complex. WB:WBGene00015306 C01G5.4 Predicted to be located in membrane. WB:WBGene00015307 C01G5.5 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. WB:WBGene00015308 ddi-1 Predicted to enable aspartic-type endopeptidase activity. Involved in negative regulation of synapse assembly. Located in cytoplasm and nucleus. Expressed widely. Is an ortholog of human DDI1 (DNA damage inducible 1 homolog 1) and DDI2 (DNA damage inducible 1 homolog 2). WB:WBGene00015309 C01G5.7 Enriched in several structures, including ABalapapapa; ABalapppapa; ADE; amphid neurons; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Doxycycline; Chlorpyrifos; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015310 fan-1 Predicted to enable 5'-3' exonuclease activity; 5'-flap endonuclease activity; and flap-structured DNA binding activity. Involved in DNA repair. Located in nucleus. Expressed in embryonic cell; germ cell; head neurons; intestine; and tail neurons. Used to study Fanconi anemia. Human ortholog(s) of this gene implicated in karyomegalic interstitial nephritis. Is an ortholog of human FAN1 (FANCD2 and FANCI associated nuclease 1). WB:WBGene00015311 C01G5.9 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00015312 C01G8.1 Expressed in germ line. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015313 hpo-32 Enriched in AVK; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including manganese chloride; bisphenol S; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015315 srbc-29 Predicted to be located in membrane. WB:WBGene00015316 srbc-30 Predicted to be located in membrane. WB:WBGene00015317 srbc-32 Predicted to be located in membrane. WB:WBGene00015318 srbc-36 Predicted to be located in membrane. WB:WBGene00015319 C02A12.7 No description available WB:WBGene00015320 C02B8.1 Enriched in several structures, including ABalaapppp; ABalapaapp; ABalappppa; ABalppappp; and ABprpapppa based on tiling array and single-cell RNA-seq studies. Is affected by several genes including glp-1; clk-1; and lin-35 based on microarray; RNA-seq; and tiling array studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015321 fbxc-38 Enriched in marginal cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by hydrogen sulfide; Tunicamycin; and indole based on microarray studies. WB:WBGene00015322 C02B8.3 Enriched in head mesodermal cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5354 and Family of unknown function (DUF5354). WB:WBGene00015323 frpr-1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in AVDL; AVDR; PVCL; and PVCR. WB:WBGene00015324 C02B8.6 Predicted to enable poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human RNF146 (ring finger protein 146). WB:WBGene00015325 C02B8.7 Enriched in NSM and dopaminergic neurons based on tiling array studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5354 and Family of unknown function (DUF5354). WB:WBGene00015326 ivd-1 Predicted to enable isovaleryl-CoA dehydrogenase activity. Involved in regulation of response to oxidative stress. Predicted to be located in mitochondrion. Expressed in head. Human ortholog(s) of this gene implicated in isovaleric acidemia. Is an ortholog of human IVD (isovaleryl-CoA dehydrogenase). WB:WBGene00015327 snpn-1 Predicted to enable SNARE binding activity. Involved in endosomal transport and positive regulation of intracellular protein transport. Predicted to be located in synaptic vesicle. Predicted to be part of BLOC-1 complex and BORC complex. Used to study Hermansky-Pudlak syndrome. Is an ortholog of human SNAPIN (SNAP associated protein). WB:WBGene00015328 C02B10.3 Predicted to enable Notch binding activity. Predicted to be located in membrane. WB:WBGene00015329 C02B10.4 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. WB:WBGene00015330 pygo-1 Enriched in several structures, including ABalppappa; ABarappppa; ABplpppaapa; germ line; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and pmk-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; Rifampin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Human PYGO1 enables methylated histone binding activity. Is an ortholog of human PYGO1 (pygopus family PHD finger 1) and PYGO2 (pygopus family PHD finger 2). WB:WBGene00015331 C02B10.6 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00015332 tyr-1 Predicted to enable metal ion binding activity and monooxygenase activity. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human DCT (dopachrome tautomerase) and TYR (tyrosinase). WB:WBGene00015333 slc-17.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be located in membrane. WB:WBGene00015334 sup-18 Predicted to enable oxidoreductase activity. Predicted to be involved in tyrosine metabolic process. Predicted to be located in membrane. Expressed in anal depressor muscle; head neurons; and vulval muscle. Human ortholog(s) of this gene implicated in thyroid dyshormonogenesis 4. Is an ortholog of human IYD (iodotyrosine deiodinase). WB:WBGene00015335 acdh-6 Predicted to enable acyl-CoA dehydrogenase activity and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to be located in cytoplasm. WB:WBGene00015336 C02D5.2 Predicted to enable oxidoreductase activity. Predicted to be located in membrane. Is an ortholog of human IFI30 (IFI30 lysosomal thiol reductase). WB:WBGene00015337 gsto-2 Predicted to enable glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytoplasm. Expressed in head; intestine; and tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Is an ortholog of human GSTO1 (glutathione S-transferase omega 1) and GSTO2 (glutathione S-transferase omega 2). WB:WBGene00015338 catp-2 Predicted to enable P-type sodium:potassium-exchanging transporter activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human ATP12A (ATPase H+/K+ transporting non-gastric alpha2 subunit) and ATP4A (ATPase H+/K+ transporting subunit alpha). WB:WBGene00015339 C02E7.6 Expressed in neurons and ventral nerve cord. WB:WBGene00015340 C02E7.7 Enriched in carbon dioxide sensory neurons; cholinergic neurons; germline precursor cell; hypodermis; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by thirty-one chemicals including methylmercury hydroxide; 1-methylnicotinamide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00015341 C02E7.8 Is affected by etr-1 and sir-2.1 based on RNA-seq and microarray studies. Is affected by Diazinon based on microarray studies. WB:WBGene00015342 C02E7.10 Predicted to be located in membrane. WB:WBGene00015344 nra-4 Involved in protein-containing complex assembly. Located in endoplasmic reticulum. Expressed in germ line; motor neurons; and non-striated muscle. Is an ortholog of human NOMO1 (NODAL modulator 1); NOMO2 (NODAL modulator 2); and NOMO3 (NODAL modulator 3). WB:WBGene00015345 C02F5.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family C02F5.10 and Family of unknown function (DUF5356). WB:WBGene00015346 C02F5.3 Predicted to enable GTP binding activity. Predicted to be involved in cytoplasmic translation. Predicted to be located in cytoplasm. Is an ortholog of human DRG2 (developmentally regulated GTP binding protein 2). WB:WBGene00015347 cids-1 Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Is an ortholog of human RPRD1A (regulation of nuclear pre-mRNA domain containing 1A). WB:WBGene00015348 C02F5.5 Enriched in several structures, including germ line; interneuron; intestine; sperm; and tail hypodermis based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-six chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: DUF236 repeat. WB:WBGene00015349 henn-1 Enables small RNA 2'-O-methyltransferase activity. Involved in RNA methylation; piRNA processing; and siRNA processing. Located in nucleoplasm and perinuclear region of cytoplasm. Expressed in germ line and somatic cell. Is an ortholog of human HENMT1 (HEN methyltransferase 1). WB:WBGene00015350 fbxl-1 Involved in several processes, including dauer entry; defecation rhythm; and regulation of defecation rhythm. Located in perikaryon and plasma membrane bounded cell projection. Is an ortholog of human FBXL2 (F-box and leucine rich repeat protein 2) and FBXL20 (F-box and leucine rich repeat protein 20). WB:WBGene00015351 C02F5.10 Enriched in several structures, including ABplpppaaa; ABprpppaaa; germ line; male distal tip cell; and neurons based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and isp-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including stavudine; Sodium Chloride; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family C02F5.10 and Family of unknown function (DUF5356). WB:WBGene00015352 C02F5.12 Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. WB:WBGene00015353 C02F5.13 Predicted to be located in membrane. Is an ortholog of human TM2D2 (TM2 domain containing 2). WB:WBGene00015354 snet-1 Involved in regulation of chemotaxis; regulation of olfactory learning; and response to pheromone. Predicted to be located in extracellular region and perikaryon. Expressed in coelomocyte and ganglia. WB:WBGene00015355 C02F12.5 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00015356 tag-278 Expressed in body wall musculature. Is predicted to encode a protein with the following domains: Protein FAM184A/B, N-terminal; Family with sequence similarity 184, A and B; and Phosphorylation site. Is an ortholog of human FAM184A (family with sequence similarity 184 member A). WB:WBGene00015357 C02F12.8 Enriched in several structures, including ABplpppapa; ABprpppapa; accessory cell; germ line; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including bisphenol A; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015359 C02G6.1 Enriched in AFD; OLL; PVD; dopaminergic neurons; and hypodermis based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including aldicarb; methylmercuric chloride; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00015360 C02G6.2 Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis involved in protein catabolic process. Predicted to be located in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease; diabetic encephalopathy; and type 2 diabetes mellitus. Is an ortholog of human IDE (insulin degrading enzyme). WB:WBGene00015361 C02H6.1 Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be located in membrane. WB:WBGene00015362 fbxa-105 Involved in innate immune response. WB:WBGene00015364 npr-19 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in M3L; M3R; URXL; and URXR. WB:WBGene00015365 C03A7.1 No description available WB:WBGene00015366 C03A7.2 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00015367 srt-64 Predicted to be located in membrane. WB:WBGene00015368 srt-65 Predicted to be located in membrane. Expressed in amphid neurons; head; and pharyngeal cell. WB:WBGene00015369 ugt-51 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1). WB:WBGene00015371 C03A7.13 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00015372 C03B1.1 Enriched in I5 neuron; MSpppaaa; head mesodermal cell; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-12; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00015373 C03B1.2 Enriched in PVPL; PVPR; body wall musculature; and neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including tryptophan; indole; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00015374 C03B1.3 Enriched in several structures, including ABplppppap; male distal tip cell; neurons; retrovesicular ganglion; and somatic gonad precursor based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by rsr-2; let-418; and dcp-66 based on tiling array and RNA-seq studies. Is affected by Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00015375 C03B1.4 Enriched in several structures, including Z1.p; Z4.a; male distal tip cell; somatic gonad precursor; and touch receptor neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; sek-1; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including tryptophan; metformin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00015376 C03B1.5 Predicted to enable ATP binding activity and non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00015377 C03B1.6 Enriched in arc ant V and neurons based on tiling array; single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including let-60; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00015378 C03B1.7 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00015379 C03B1.9 Is affected by rsr-2; aak-1; and aak-2 based on tiling array and RNA-seq studies. Is affected by resveratrol and Atrazine based on microarray studies. WB:WBGene00015380 C03B1.10 Enriched in AFD; I5 neuron; MSpaaaaa; PLM; and pharyngeal neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including mex-1; drh-3; and spn-4 based on tiling array and RNA-seq studies. Is affected by Chlorpyrifos based on microarray studies. WB:WBGene00015381 C03B1.13 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00015382 C03B1.14 Enriched in several structures, including ABaraapapaa; ABaraapppaa; ABplppppap; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015385 C03B8.2 Enriched in several structures, including ABalaapppp; ABalapaapp; ABalappppa; ABalppappp; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00015386 C03B8.3 Predicted to be located in mitochondrion. WB:WBGene00015387 kcnl-3 Predicted to enable calmodulin binding activity and small conductance calcium-activated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in neuron projection; neuronal cell body; and plasma membrane. Is an ortholog of human KCNN1 (potassium calcium-activated channel subfamily N member 1). WB:WBGene00015388 C03F11.2 Enriched in ABarpaaa; NSM; and mc3 based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; rotenone; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Human MBLAC1 enables RNA endonuclease activity and metal ion binding activity. Is predicted to encode a protein with the following domains: Metallo-beta-lactamase; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; Metallo-beta-lactamase domain-containing protein 1; and Metallo-beta-lactamase superfamily. Is an ortholog of human MBLAC1 (metallo-beta-lactamase domain containing 1). WB:WBGene00015389 scav-1 Predicted to enable scavenger receptor activity. Predicted to be involved in endocytosis. Predicted to be located in cytoplasm. Is an ortholog of human SCARB1 (scavenger receptor class B member 1). WB:WBGene00015390 C03F11.4 Enriched in several structures, including coelomocyte; germ line; head mesodermal cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015391 sdha-1 Predicted to enable electron transfer activity; flavin adenine dinucleotide binding activity; and succinate dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone. Located in mitochondrion. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including Leigh disease; dilated cardiomyopathy 1GG; and mitochondrial complex II deficiency. Is an ortholog of human SDHA (succinate dehydrogenase complex flavoprotein subunit A). WB:WBGene00015392 nspc-7 Enriched in excretory duct; excretory gland cell; and excretory pore based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; microarray; and tiling array studies. Is affected by seventeen chemicals including Ethanol; rotenone; and mianserin based on RNA-seq and microarray studies. WB:WBGene00015393 exc-13 Predicted to be located in extracellular region. WB:WBGene00015394 C03G6.6 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00015395 nhr-147 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00015396 nhr-148 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head. WB:WBGene00015397 nhr-149 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00015398 tag-293 Enriched in AFD; g1P; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including 1-methylnicotinamide; nicotinic acid; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00015399 cyp-35A1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2D6 (cytochrome P450 family 2 subfamily D member 6); and CYP2E1 (cytochrome P450 family 2 subfamily E member 1). WB:WBGene00015400 cyp-35A2 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). WB:WBGene00015401 srsx-24 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00015402 C03G6.17 Enriched in several structures, including GABAergic neurons; XXX cell; excretory cell; mechanosensory neurons; and neuronal sheath cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Tunicamycin; D-glucose; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; Domain of unknown function DUF1248; and Protein of unknown function (DUF1248). WB:WBGene00015403 clec-10 Enriched in intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by twenty-seven chemicals including Heme; tryptophan; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00015404 nstp-4 Predicted to enable UDP-galactose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport and carbohydrate transport. Predicted to be located in Golgi membrane. Expressed in head; intestinal muscle; and tail. Is an ortholog of human SLC35A3 (solute carrier family 35 member A3). WB:WBGene00015405 C03H5.3 Enriched in AFD; body wall muscle cell; and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eight chemicals including rotenone; Zidovudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015406 C03H5.4 Predicted to enable calcium ion binding activity and phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion; lipid catabolic process; and phospholipid metabolic process. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including adult respiratory distress syndrome; cholecystolithiasis; and familial benign fleck retina. Is an ortholog of human PLA2G2A (phospholipase A2 group IIA); PLA2G2E (phospholipase A2 group IIE); and PLA2G5 (phospholipase A2 group V). WB:WBGene00015407 C03H5.5 Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. WB:WBGene00015408 C03H5.6 Enriched in neurons; retrovesicular ganglion; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and sek-1 based on RNA-seq; microarray; and proteomic studies. Is affected by nine chemicals including rotenone; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00015409 C03H5.7 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00015410 tbc-6 Predicted to enable GTPase activator activity. Is an ortholog of human GRTP1 (growth hormone regulated TBC protein 1). WB:WBGene00015411 srz-60 Predicted to be located in membrane. WB:WBGene00015412 lgc-9 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00015413 pdhb-1 Predicted to enable pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Expressed in several structures, including head. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Is an ortholog of human PDHB (pyruvate dehydrogenase E1 subunit beta). WB:WBGene00015414 C04C3.4 Enriched in FLPL and FLPR based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and lin-35 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015416 C04C3.6 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00015417 C04C3.7 Predicted to be located in membrane. WB:WBGene00015418 pac-1 Enables GTPase activator activity. Involved in Rho protein signal transduction; protein localization; and regulation of gastrulation. Located in cell junction. Expressed in anus; epithelial cell; hypodermis; pharynx; and pm7. Is an ortholog of human ARHGAP23 (Rho GTPase activating protein 23). WB:WBGene00015419 srsx-18 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in linker cell. WB:WBGene00015421 C04E6.4 Predicted to be located in membrane. WB:WBGene00015422 C04E6.5 Predicted to enable cysteine-type deubiquitinase activity. WB:WBGene00015423 C04E6.7 Enriched in several structures, including ABplppppap; coelomocyte; intestine; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Haloacid dehalogenase-like hydrolase; Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal; HAD-like superfamily; HAD hydrolase, subfamily IA; Phosphoglycolate phosphatase-like, domain 2; and HAD superfamily. WB:WBGene00015424 C04E6.8 Enriched in ADF; ADFL; ADFR; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: NTF2-like domain superfamily. WB:WBGene00015425 C04E6.11 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in regulation of mitochondrial translation. Predicted to be located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in French Canadian Leigh disease and Leigh disease. Is an ortholog of human LRPPRC (leucine rich pentatricopeptide repeat containing). WB:WBGene00015426 C04E6.12 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00015427 C04E6.13 Predicted to be involved in cell division. WB:WBGene00015428 C04E7.1 Is affected by several genes including eat-2; eri-1; and mes-3 based on RNA-seq and microarray studies. Is affected by adsorbable organic bromine compound; Sirolimus; and allantoin based on microarray studies. WB:WBGene00015429 sor-3 Predicted to enable chromatin binding activity and histone binding activity. Involved in several processes, including negative regulation of DNA-templated transcription; nematode larval development; and neuron differentiation. Located in cytoplasm and nucleus. Expressed widely. WB:WBGene00015430 C04E7.3 Enriched in coelomocyte; neurons; rectal epithelial cell; and rectum based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; pgl-1; and aak-2 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including rotenone; Cry5B; and stavudine based on RNA-seq and microarray studies. WB:WBGene00015432 srbc-4 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00015433 C04E12.2 Enriched in head mesodermal cell; hypodermis; and muscle cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00015434 C04E12.4 Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Predicted to be involved in glycoprotein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Predicted to be located in cytosol and nucleus. WB:WBGene00015435 C04E12.5 Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Predicted to be involved in glycoprotein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Predicted to be located in cytosol and nucleus. WB:WBGene00015436 C04E12.6 Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Tunicamycin; resveratrol; and Sirolimus based on microarray studies. WB:WBGene00015437 scrm-3 Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be located in plasma membrane. Expressed in body wall musculature and touch receptor neurons. Is an ortholog of several human genes including PLSCR2 (phospholipid scramblase 2); PLSCR3 (phospholipid scramblase 3); and PLSCR4 (phospholipid scramblase 4). WB:WBGene00015438 srbc-2 Predicted to be located in membrane. WB:WBGene00015439 C04E12.10 Is affected by several genes including daf-16; daf-12; and lin-4 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00015440 arrd-20 Enriched in intestine; neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-12; eat-2; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00015441 arrd-21 Enriched in Z1.p; Z4.a; gon_male_dtc anterior; gon_male_dtc posterior; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015442 C04F1.1 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00015444 C04F5.2 Predicted to be located in membrane. WB:WBGene00015446 srab-1 Predicted to be located in membrane. Expressed in AWBL and AWBR. WB:WBGene00015447 srab-2 Predicted to be located in membrane. WB:WBGene00015448 srab-3 Predicted to be located in membrane. Expressed in ganglia. WB:WBGene00015449 ugt-63 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Expressed in hypodermis and muscle cell. WB:WBGene00015450 C04F5.8 Predicted to enable methyltransferase activity. Predicted to be involved in tRNA (guanine-N7)-methylation. WB:WBGene00015451 C04F5.9 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00015453 C04G6.2 Enriched in hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty chemicals including Nitric Oxide; rotenone; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00015454 C04G6.4 Predicted to enable protein kinase A regulatory subunit binding activity. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Is an ortholog of human PRRC1 (proline rich coiled-coil 1). WB:WBGene00015455 txt-9 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00015456 C04G6.6 Enriched in several structures, including ABplapaaaa; ABprapaaaa; germ line; head mesodermal cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including manganese chloride; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00015457 idpb-3 Enriched in body wall muscle cell; cholinergic neurons; hypodermis; and pharyngeal cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including multi-walled carbon nanotube; Zidovudine; and glycine based on RNA-seq and microarray studies. WB:WBGene00015458 idpb-1 Expressed in pm6. WB:WBGene00015459 C04G6.11 Predicted to be located in membrane. WB:WBGene00015460 C05C8.1 Enriched in NSM; coelomocyte; dopaminergic neurons; germ line; and germline precursor cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by five chemicals including rotenone; paraquat; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily and Leucine-rich repeat, cysteine-containing subtype. Is an ortholog of human DMAC2L (distal membrane arm assembly component 2 like). WB:WBGene00015461 krr-1 Predicted to enable RNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Expressed in head and tail. Is an ortholog of human KRR1 (KRR1 small subunit processome component homolog). WB:WBGene00015462 C05C8.5 Predicted to enable exonuclease activity. Predicted to be located in nucleus. Is an ortholog of human REXO5 (RNA exonuclease 5). WB:WBGene00015463 hpo-9 Predicted to be involved in adult locomotory behavior; circadian behavior; and modulation of chemical synaptic transmission. Predicted to be located in cytoplasm. Expressed in dopaminergic neurons and hypodermal cell. Is an ortholog of human BTBD9 (BTB domain containing 9). WB:WBGene00015464 C05C8.7 Predicted to enable mannose-6-phosphate isomerase activity. Predicted to be involved in GDP-mannose biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ib. Is an ortholog of human MPI (mannose phosphate isomerase). WB:WBGene00015465 C05C8.8 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00015466 hyls-1 Involved in cilium assembly and foraging behavior. Located in centriole and non-motile cilium. Expressed in amphid neurons; inner labial neurons; and outer labial neurons. Used to study hydrolethalus syndrome. Human ortholog(s) of this gene implicated in hydrolethalus syndrome 1. Is an ortholog of human HYLS1 (HYLS1 centriolar and ciliogenesis associated). WB:WBGene00015467 basl-1 Predicted to enable aromatic-L-amino-acid decarboxylase activity. Predicted to be involved in catecholamine metabolic process and serotonin biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including aromatic L-amino acid decarboxylase deficiency; bipolar disorder; and hyperinsulinism. Is an ortholog of human DDC (dopa decarboxylase). WB:WBGene00015468 madf-11 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Expressed in hermaphrodite distal tip cell; intestine; neurons; pharyngeal muscle cell; and ventral nerve cord. WB:WBGene00015469 C05D2.8 Enriched in MSpppaaa; head mesodermal cell; intestine; mechanosensory neurons; and pharyngeal muscle cell based on SAGE; microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq; proteomic; and microarray studies. WB:WBGene00015470 wdr-37 Enriched in several structures, including ABalaaaala; ABalaapaaa; coelomocyte; germ line; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; sir-2.1; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in neurooculocardiogenitourinary syndrome. Is predicted to encode a protein with the following domains: WD40 repeat; WD domain, G-beta repeat; WD40-repeat-containing domain superfamily; WD40/YVTN repeat-like-containing domain superfamily; and G-protein beta WD-40 repeat. Is an ortholog of human WDR37 (WD repeat domain 37). WB:WBGene00015471 lmp-2 Predicted to be involved in establishment of protein localization to organelle. Predicted to be located in late endosome membrane; lysosomal membrane; and plasma membrane. Is an ortholog of human LAMP1 (lysosomal associated membrane protein 1). WB:WBGene00015472 C05D9.3 Predicted to be involved in integrin-mediated signaling pathway. Located in plasma membrane. WB:WBGene00015473 C05D9.4 Enriched in several structures, including AIZ; NSM; accessory cell; arc ant V; and mechanosensory neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Zidovudine; Rifampin; and Sirolimus based on RNA-seq studies. WB:WBGene00015474 C05D9.7 Predicted to be located in membrane. WB:WBGene00015476 C05D9.9 Enriched in several structures, including B cell; MSaapaapa; MSpapaapa; dopaminergic neurons; and mechanosensory neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including rotenone; Tunicamycin; and Cadmium Chloride based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Immunoglobulin-like fold and Immunoglobulin-like domain superfamily. WB:WBGene00015477 attf-4 Predicted to enable DNA binding activity. Expressed in head muscle; hypodermis; pharyngeal-intestinal valve; tail neurons; and ventral nerve cord. WB:WBGene00015478 mapk-15 Predicted to enable protein serine/threonine kinase activity. Involved in dopamine uptake; protein localization to ciliary transition zone; and regulation of cilium assembly. Located in axoneme; cell-cell junction; and ciliary basal body. Expressed in neurons; oocyte; and in male. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human MAPK15 (mitogen-activated protein kinase 15). WB:WBGene00015479 wht-1 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including gout; hematologic cancer (multiple); and toxic encephalopathy. Is an ortholog of human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)). WB:WBGene00015480 C05D10.4 Enriched in several structures, including ABaraappaa; MSaaaaapa; excretory cell; neurons; and pharyngeal gland cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including aldicarb; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SAM domain (Sterile alpha motif); Sterile alpha motif/pointed domain superfamily; Sterile alpha motif domain; and Phosphorylation site. WB:WBGene00015481 C05D11.1 Predicted to enable metal ion binding activity. WB:WBGene00015483 C05D11.5 Predicted to enable hydroxypyruvate isomerase activity. Predicted to be involved in glyoxylate metabolic process. Is an ortholog of human HYI (hydroxypyruvate isomerase (putative)). WB:WBGene00015484 atgl-1 Predicted to enable triglyceride lipase activity. Predicted to be involved in lipid homeostasis and triglyceride catabolic process. Located in lipid droplet. Expressed in intestine; nerve ring; and ventral nerve cord. Used to study Chanarin-Dorfman syndrome. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive congenital ichthyosis 10; liver disease (multiple); and type 2 diabetes mellitus. Is an ortholog of human PNPLA2 (patatin like phospholipase domain containing 2) and PNPLA3 (patatin like phospholipase domain containing 3). WB:WBGene00015485 C05D11.8 Enriched in several structures, including ABalaapppa; ABalapaapa; ABplapaaap; ABprapaaap; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including aldicarb; rotenone; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Retinoic acid induced 16-like protein; FHF complex subunit HOOK-interacting protein, C-terminal; Family of unknown function (DUF5917); FHF complex subunit HOOK interacting protein; and Phosphorylation site. Is an ortholog of human FHIP1A (FHF complex subunit HOOK interacting protein 1A) and FHIP1B (FHF complex subunit HOOK interacting protein 1B). WB:WBGene00015486 popl-1 Predicted to enable RNA binding activity and hydrolase activity. Predicted to be involved in tRNA processing. Predicted to be located in nucleolus. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Human ortholog(s) of this gene implicated in anauxetic dysplasia 2. Is an ortholog of human POP1 (POP1 homolog, ribonuclease P/MRP subunit). WB:WBGene00015487 mrps-17 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS17 (mitochondrial ribosomal protein S17). WB:WBGene00015488 C05D11.13 Enriched in intestine; marginal cell; neurons; and rect_D based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by rotenone; Alovudine; and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00015489 C05E4.7 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and set-2 based on tiling array; microarray; and RNA-seq studies. Is affected by Tunicamycin and Sirolimus based on microarray studies. WB:WBGene00015490 C05E4.8 No description available WB:WBGene00015491 C05E4.12 Enriched in MSpppaaa; NSM; and head mesodermal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and clk-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00015492 lnp-1 Predicted to enable metal ion binding activity. Involved in several processes, including regulation of egg-laying behavior; synapse assembly; and synaptic vesicle transport. Located in several cellular components, including neuron projection; neuronal cell body; and synaptic vesicle. Expressed in hypodermis; muscle cell; and neurons. Is an ortholog of human LNPK (lunapark, ER junction formation factor). WB:WBGene00015493 C05E11.2 Predicted to be located in membrane. WB:WBGene00015494 C05E11.3 Predicted to be located in lysosomal membrane. WB:WBGene00015495 C05E11.6 Predicted to be involved in circadian rhythm. WB:WBGene00015496 C05E11.7 Enriched in arcade cell and pharyngeal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including aldicarb; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00015497 nhr-76 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in positive regulation of fatty acid beta-oxidation by octopamine signaling pathway; positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including body wall musculature; excretory gland cell; intestine; pharynx; and vulval muscle. WB:WBGene00015499 ints-1 Predicted to be involved in U2 snRNA 3'-end processing. Predicted to be part of integrator complex. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies. Is an ortholog of human INTS1 (integrator complex subunit 1). WB:WBGene00015500 C06A5.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00015501 C06A5.3 Predicted to be located in mitochondrial inner membrane; mitochondrial intermembrane space; and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Is an ortholog of human HDGF (heparin binding growth factor). WB:WBGene00015502 madf-7 No description available WB:WBGene00015503 C06A5.5 No description available WB:WBGene00015504 simr-1 Involved in multicellular organismal reproductive process; positive regulation of oogenesis; and siRNA processing. Located in perinuclear region of cytoplasm. Expressed in germ cell. WB:WBGene00015505 C06A5.8 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Expressed in germ line and oocyte. Is an ortholog of human RNF227 (ring finger protein 227). WB:WBGene00015506 C06A5.10 No description available WB:WBGene00015507 C06A6.2 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. WB:WBGene00015508 mvb-12 Involved in endosome to lysosome transport via multivesicular body sorting pathway and receptor catabolic process. Located in cytosol and endosome membrane. Part of ESCRT I complex. Expressed in amphid neurons; hypodermis; intestine; and pm7. Is an ortholog of human MVB12B (multivesicular body subunit 12B). WB:WBGene00015509 C06A6.4 Predicted to enable aminoacylase activity. Predicted to be involved in amino acid metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ACY1 (aminoacylase 1). WB:WBGene00015510 erp-44.2 Predicted to enable protein disulfide isomerase activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment. Is an ortholog of human ERP44 (endoplasmic reticulum protein 44). WB:WBGene00015511 C06A6.7 Enriched in several structures, including ABarpapaapp; ABplaaaaapp; cephalic sheath cell; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by six chemicals including D-glucose; antimycin; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00015512 mthf-1 Predicted to enable FAD binding activity and methylenetetrahydrofolate reductase (NAD(P)H) activity. Predicted to be involved in methionine biosynthetic process and tetrahydrofolate interconversion. Expressed in muscle cell and tail. Used to study lipid metabolism disorder. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); hematologic cancer (multiple); and liver disease (multiple). Is an ortholog of human MTHFR (methylenetetrahydrofolate reductase). WB:WBGene00015513 snpc-1.1 Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be part of snRNA-activating protein complex. Is an ortholog of human SNAPC1 (small nuclear RNA activating complex polypeptide 1). WB:WBGene00015514 srlf-1 Enriched in several structures, including accessory cell; anterior arcade cell; anterior hypodermis; ciliated neurons; and somatic nervous system based on Chronogram; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; microarray; and RNA-seq studies. Is affected by twenty chemicals including rotenone; mianserin; and D-glucose based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00015515 spdl-1 Involved in several processes, including nuclear chromosome segregation; positive regulation of kinetochore assembly; and regulation of chromosome segregation. Located in kinetochore and microtubule. WB:WBGene00015516 C06A8.6 Predicted to be located in cytoplasm. Is an ortholog of human PPP1R7 (protein phosphatase 1 regulatory subunit 7). WB:WBGene00015517 C06A8.8 Predicted to be located in cilium. Human ortholog(s) of this gene implicated in Joubert syndrome 25 and autosomal recessive intellectual developmental disorder 77. Is an ortholog of human CEP104 (centrosomal protein 104). WB:WBGene00015518 C06E1.1 Enriched in several structures, including ABalapppaa; ABalpapppa; ABalppappa; ciliated neurons; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including rotenone; bisphenol S; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TB2/DP1/HVA22-related protein and TB2/DP1, HVA22 family. WB:WBGene00015519 doxa-1 Predicted to be involved in protein transport. Predicted to be located in membrane. Expressed in gonad; hypodermis; terminal bulb; and vulva. Human ortholog(s) of this gene implicated in thyroid dyshormonogenesis 5. Is an ortholog of human DUOXA1 (dual oxidase maturation factor 1) and DUOXA2 (dual oxidase maturation factor 2). WB:WBGene00015520 fip-3 Enriched in germ line; rect_D; rect_VL; and rect_VR based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; tph-1; and cat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Mercuric Chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Fungus-induced protein. WB:WBGene00015521 fipr-16 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Fungus-induced protein. WB:WBGene00015522 C06E1.7 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00015523 ztf-30 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00015524 C06E1.9 Predicted to enable ubiquitin binding activity. Predicted to be involved in regulation of DNA-templated transcription. WB:WBGene00015525 rha-2 Predicted to enable RNA binding activity and helicase activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Human ortholog(s) of this gene implicated in 46,XY sex reversal. Is an ortholog of human DHX37 (DEAH-box helicase 37). WB:WBGene00015526 C06E1.11 Enriched in excretory duct; excretory pore; germ line; germline precursor cell; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; hsf-1; and nhr-49 based on RNA-seq studies. Is affected by nine chemicals including stavudine; tert-Butylhydroperoxide; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00015527 C06E2.1 Enriched in several structures, including ABalppppppa; ABplaapappp; ABpraaapppa; ABpraapappp; and ciliated neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015528 C06E2.2 Enriched in ADFL; ADFR; AWAL; AWAR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; clk-1; and pgrn-1 based on RNA-seq and microarray studies. WB:WBGene00015529 C06E2.5 Enriched in Z1.p; Z4.a; intestine; male distal tip cell; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00015530 C06E4.1 Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in DNA biosynthetic process. WB:WBGene00015531 C06E4.2 Enriched in several structures, including anterior hypodermis; head ganglion; interfacial epithelial cell; pharynx; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including stavudine; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00015532 C06E4.3 Enriched in amphid neurons; amphid sheath cell; intestine; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by twenty-one chemicals including tryptophan; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. Human HSD17B14 enables estradiol 17-beta-dehydrogenase [NAD(P)] activity; identical protein binding activity; and testosterone 17-beta-dehydrogenase (NADP+) activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and Enoyl-(Acyl carrier protein) reductase. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00015533 C06E4.4 Is affected by several genes including eat-2; lin-15B; and xpo-1 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00015534 C06E4.5 Predicted to enable histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. WB:WBGene00015535 C06E4.6 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00015536 glb-2 Predicted to enable heme binding activity and oxygen binding activity. Expressed in head neurons. WB:WBGene00015537 C06E4.8 Enriched in several structures, including amphid sheath cell; intestine; male distal tip cell; muscle cell; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Tunicamycin; D-glucose; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00015538 sams-3 Predicted to enable methionine adenosyltransferase activity. Predicted to be involved in S-adenosylmethionine biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in hypermethioninemia and lung cancer. Is an ortholog of human MAT1A (methionine adenosyltransferase 1A) and MAT2A (methionine adenosyltransferase 2A). WB:WBGene00015539 C06E7.2 Enriched in anterior arcade cell; cephalic sheath cell; neurons; retrovesicular ganglion; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015540 sams-4 Predicted to enable methionine adenosyltransferase activity. Predicted to be involved in S-adenosylmethionine biosynthetic process. Predicted to be located in cytosol. Expressed in pharyngeal gland cell. Human ortholog(s) of this gene implicated in hypermethioninemia and lung cancer. Is an ortholog of human MAT1A (methionine adenosyltransferase 1A) and MAT2A (methionine adenosyltransferase 2A). WB:WBGene00015541 C06E7.4 Enriched in several structures, including hyp3; interfacial epithelial cell; neurons; pm6; and rect_D based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including Ethanol; 1-methylnicotinamide; and D-glucopyranose based on RNA-seq and microarray studies. WB:WBGene00015543 C06E8.4 No description available WB:WBGene00015544 C06E8.5 Predicted to enable lipid binding activity. Predicted to be located in extracellular space. Is an ortholog of human BPIFC (BPI fold containing family C). WB:WBGene00015545 C06G1.1 Predicted to enable lipid binding activity. Predicted to be located in extracellular space. Expressed in excretory system; seam cell; tail hypodermis; and vulval muscle. Is an ortholog of human BPIFC (BPI fold containing family C). WB:WBGene00015546 cpg-19 Enriched in anterior hypodermis; arcade cell; head mesodermal cell; neurons; and pharynx based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by twenty chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00015547 ain-1 Involved in several processes, including embryo development; negative regulation of gene expression; and regulation of developmental process. Located in P-body. Expressed widely. WB:WBGene00015549 C06G3.3 Enriched in arcade cell; head mesodermal cell; head motor neurons; and pharyngeal interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Tunicamycin; mianserin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00015550 C06G3.4 Enriched in AVK based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015551 adah-1 Predicted to enable adenosine deaminase activity. Predicted to be involved in negative regulation of adenosine receptor signaling pathway and purine-containing compound metabolic process. Predicted to be located in cytosol and external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Legionnaires' disease; gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of human ADA (adenosine deaminase). WB:WBGene00015552 gldi-4 Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and protein kinase C binding activity. Predicted to be involved in aggrephagy; endosome organization; and mitophagy. Predicted to be located in aggresome and amphisome. Human ortholog(s) of this gene implicated in Paget's disease of bone 3; distal myopathy with rimmed vacuoles; and neurodegenerative disease (multiple). Is an ortholog of human SQSTM1 (sequestosome 1). WB:WBGene00015553 trxr-1 Predicted to enable thioredoxin-disulfide reductase (NADP) activity. Involved in ecdysis, collagen and cuticulin-based cuticle. Predicted to be located in cytosol and mitochondrion. Expressed in several structures, including hypodermis; interfacial epithelial cell; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; colorectal adenoma; and colorectal carcinoma. Is an ortholog of human TXNRD3 (thioredoxin reductase 3). WB:WBGene00015554 C06G3.8 Predicted to enable DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination and response to ionizing radiation. Predicted to be part of SOSS complex. Is an ortholog of human NABP1 (nucleic acid binding protein 1) and NABP2 (nucleic acid binding protein 2). WB:WBGene00015555 ufl-1 Predicted to enable UFM1 transferase activity. Predicted to be involved in regulation of proteasomal ubiquitin-dependent protein catabolic process and response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum membrane. Expressed in intestine. Is an ortholog of human UFL1 (UFM1 specific ligase 1). WB:WBGene00015556 C06G3.12 No description available WB:WBGene00015557 hrpk-2 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in nervous system development and regulation of gene expression. Predicted to be located in cytosol and nucleus. WB:WBGene00015558 C06G4.4 Enriched in several structures, including AVG; RIM; command interneuron; germ line; and sperm based on Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by fifteen chemicals including methylmercuric chloride; mianserin; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00015559 npr-17 Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection. Expressed in ganglia and head neurons. Is an ortholog of human SSTR4 (somatostatin receptor 4). WB:WBGene00015560 C07A12.2 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00015561 C07A12.7 Predicted to enable clathrin binding activity. Predicted to be involved in signal transduction. Predicted to be located in endosome and membrane. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human TOM1 (target of myb1 membrane trafficking protein) and TOM1L2 (target of myb1 like 2 membrane trafficking protein). WB:WBGene00015562 C07D8.2 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; npr-1; and nhr-49 based on microarray and RNA-seq studies. Is affected by Cadmium Chloride and resveratrol based on RNA-seq and microarray studies. WB:WBGene00015564 C07D8.5 Enriched in AMsoL; AMsoR; and ventral nerve cord based on tiling array and single-cell RNA-seq studies. Is affected by several genes including skn-1; clk-1; and npr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: NADP-dependent oxidoreductase domain; NADP-dependent oxidoreductase domain superfamily; and Aldo/keto reductase family. Is an ortholog of human AKR1C8 (aldo-keto reductase family 1 member C8). WB:WBGene00015565 C07D8.6 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including diabetic neuropathy; gastrointestinal system cancer (multiple); and type 2 diabetes mellitus. Is an ortholog of human AKR1B1 (aldo-keto reductase family 1 member B); AKR1B10 (aldo-keto reductase family 1 member B10); and AKR1B15 (aldo-keto reductase family 1 member B15). WB:WBGene00015566 C07D10.1 Predicted to enable SCF ubiquitin ligase complex binding activity. WB:WBGene00015567 bath-44 Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to be located in cytoplasm and nucleus. WB:WBGene00015568 sre-3 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00015569 C07D10.5 Enriched in several structures, including ABalpapaap; ABalpppapa; ABarappaap; male distal tip cell; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq; microarray; and proteomic studies. WB:WBGene00015570 C07F11.2 Enriched in accessory cell; excretory cell; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray; RNA-seq; and tiling array studies. Is affected by seven chemicals including allantoin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015572 C07G1.6 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00015573 C07G1.7 Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by ten chemicals including nicotinic acid; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00015574 irg-1 Involved in antibacterial innate immune response and defense response to Gram-negative bacterium. WB:WBGene00015575 srbc-35 Is affected by several genes including let-60; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies. WB:WBGene00015576 C07G3.8 Enriched in amphid sheath cell and arcade cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by Tunicamycin; Alovudine; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00015577 ugt-64 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00015578 C07G3.10 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. WB:WBGene00015579 C07H6.2 Predicted to enable protein phosphatase 1 binding activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be located in nucleus. Is an ortholog of human PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11). WB:WBGene00015580 cls-1 Predicted to enable microtubule binding activity. Involved in microtubule cytoskeleton organization and positive regulation of microtubule depolymerization. Predicted to be located in basal cortex; kinetochore; and microtubule cytoskeleton. Expressed in head and tail. Is an ortholog of human CLASP2 (cytoplasmic linker associated protein 2). WB:WBGene00015581 sap-140 Predicted to enable RNA binding activity. Predicted to be involved in RNA processing. Predicted to be located in nucleus. Is an ortholog of human U2SURP (U2 snRNP associated SURP domain containing). WB:WBGene00015582 C07H6.9 Predicted to be located in membrane. WB:WBGene00015583 C08A9.3 Predicted to enable RNA transmembrane transporter activity and double-stranded RNA binding activity. Predicted to be involved in RNA transport. Predicted to be located in lysosome and plasma membrane. WB:WBGene00015586 lido-1 Predicted to be located in nucleus. WB:WBGene00015587 lido-2 Predicted to be located in nucleus. WB:WBGene00015588 lido-3 Enriched in ABalaapppa and ABalapaapa based on single-cell RNA-seq studies. Is affected by several genes including sir-2.1; csr-1; and pqm-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015589 lido-4 Predicted to be located in nucleus. WB:WBGene00015590 bath-15 Predicted to be involved in protein ubiquitination. WB:WBGene00015591 cyk-7 Involved in intercellular bridge organization. Located in Flemming body. WB:WBGene00015592 C08D8.1 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00015593 C08E3.1 Enriched in ciliated neurons; head mesodermal cell; and intestine based on RNA-seq; proteomic; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including methylmercury hydroxide; Mercuric Chloride; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00015594 btb-15 Is affected by several genes including eat-2; hpl-2; and smn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00015595 bath-33 Enriched in ABalpppapa; ABpraaaapa; and ABprpapppa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and alg-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; bisphenol A; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00015596 fbxa-161 Enriched in intestine based on microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including tryptophan; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00015597 fbxa-162 Enriched in dopaminergic neurons; head mesodermal cell; intestine; and muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twenty-five chemicals including methylmercury hydroxide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00015598 fbxa-163 Enriched in body wall muscle cell; intestine; and neurons based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-three chemicals including methylmercuric chloride; rotenone; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00015599 fbxa-164 Enriched in intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including aldicarb; Tunicamycin; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00015600 fbxa-165 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00015601 fbxa-166 Enriched in intestine and pharynx based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercury hydroxide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00015602 fbxa-158 Enriched in ALM; PLM; intestine; and sensory neurons based on tiling array; microarray; and RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including methylmercury hydroxide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00015603 fbxa-159 Is affected by several genes including eat-2; npr-1; and isp-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00015604 fbxa-160 Is affected by several genes including lin-35; lin-15B; and rsr-2 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol and copper sulfate based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00015605 C08E3.13 Expressed in intestine and vulva. WB:WBGene00015606 math-2 Enriched in NSM based on tiling array studies. Is affected by several genes including mex-1; let-418; and chd-3 based on tiling array and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00015607 fbxb-13 Enriched in several structures, including ABalapaaaa; ABalappapa; ABplapppaa; ABplpaaaaa; and ABplpppaaa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; allantoin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00015608 math-3 Enriched in head mesodermal cell; intestine; mechanosensory neurons; and pharyngeal muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; rotenone; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015609 math-4 Enriched in body wall muscle cell from MS lineage; head mesodermal cell; intestine; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including hydrogen sulfide; Zidovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015610 C08F1.6 Predicted to be located in membrane. WB:WBGene00015611 C08F1.8 Predicted to be located in membrane. WB:WBGene00015612 C08F1.9 No description available WB:WBGene00015613 C08F1.10 Predicted to be located in membrane. WB:WBGene00015614 C08G5.1 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and drh-3 based on RNA-seq and microarray studies. Is affected by six chemicals including aldicarb; Tunicamycin; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00015615 fbxc-48 Enriched in germ line; motor neurons; touch receptor neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including Psoralens; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF3557. WB:WBGene00015616 C08G5.3 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and hsp-6 based on RNA-seq; tiling array; and microarray studies. Is affected by fourteen chemicals including hydrogen sulfide; methylmercuric chloride; and Mercuric Chloride based on microarray and RNA-seq studies. WB:WBGene00015618 C08G5.6 Predicted to be located in membrane. WB:WBGene00015619 C08G9.1 Predicted to be located in membrane. WB:WBGene00015620 C08G9.2 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular space. Expressed in head neurons and pharynx. Human ortholog(s) of this gene implicated in severe acute respiratory syndrome. Is an ortholog of several human genes including PI3 (peptidase inhibitor 3); SLPI (secretory leukocyte peptidase inhibitor); and WFDC12 (WAP four-disulfide core domain 12). WB:WBGene00015621 C09B7.2 Predicted to be located in membrane. WB:WBGene00015622 C09B8.3 Predicted to be located in membrane. Predicted to be part of acetylcholine-gated channel complex. WB:WBGene00015623 C09B8.4 Predicted to be located in nuclear outer membrane. Human ortholog(s) of this gene implicated in craniotubular dysplasia Ikegawa type. Is an ortholog of human TMEM53 (transmembrane protein 53). WB:WBGene00015624 lelo-3 Enriched in several structures, including ABalaapppa; MSpppaaa; germ line; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including aldicarb; methylmercury hydroxide; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF3557. WB:WBGene00015625 C09B8.8 Predicted to be located in membrane. WB:WBGene00015626 C09B9.1 Predicted to be located in membrane. WB:WBGene00015627 C09B9.2 Predicted to be located in membrane. WB:WBGene00015628 best-6 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00015629 C09B9.4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00015630 C09B9.7 Predicted to be located in membrane. WB:WBGene00015631 clec-89 Predicted to enable signaling receptor activity. WB:WBGene00015632 C09D4.1 Predicted to enable heme binding activity and heme transmembrane transporter activity. Predicted to be involved in heme export. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Is an ortholog of human FLVCR1 (FLVCR choline and heme transporter 1) and FLVCR2 (FLVCR choline and putative heme transporter 2). WB:WBGene00015633 C09D4.2 Enriched in several structures, including AVH; HSN; MC neuron; MSpppaaa; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; Cry5B; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF4773) and Domain of unknown function DUF4773. WB:WBGene00015634 C09D4.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00015635 C09D4.4 Predicted to be involved in cellular lipid metabolic process. Is an ortholog of human FAM135A (family with sequence similarity 135 member A) and FAM135B (family with sequence similarity 135 member B). WB:WBGene00015636 C09D4.6 Predicted to be located in membrane. WB:WBGene00015637 srxa-5 Predicted to be located in membrane. Expressed in head neurons; nervous system; and pharyngeal neurons. WB:WBGene00015638 C09E7.4 Predicted to enable protein dimerization activity. WB:WBGene00015639 C09E7.5 Enriched in ABaraappaa and NSM based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and rrf-1 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; Rifampin; and Sirolimus based on RNA-seq studies. WB:WBGene00015640 C09E7.6 Enriched in AVA; PVM; germ line; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00015641 C09E7.7 Predicted to be involved in innate immune response. WB:WBGene00015642 C09E7.8 Predicted to enable metal ion binding activity. Predicted to be involved in innate immune response. Expressed in head. WB:WBGene00015644 C09E8.1 Predicted to enable symporter activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00015645 lips-7 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. Expressed in excretory system; head; rectum; and vulva. WB:WBGene00015646 mlt-10 Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and epidermis development. Located in extracellular space. Expressed in hypodermal cell and pharyngeal epithelial cell. WB:WBGene00015647 C09F5.1 Predicted to be located in membrane. Expressed in hypodermal cell; intestine; and vulva. WB:WBGene00015648 orai-1 Enables store-operated calcium channel activity. Involved in ovulation and store-operated calcium entry. Located in apical plasma membrane and basolateral plasma membrane. Part of voltage-gated calcium channel complex. Expressed in gonadal sheath cell; head; and tail. Human ortholog(s) of this gene implicated in immunodeficiency 9 and tubular aggregate myopathy 2. Is an ortholog of human ORAI2 (ORAI calcium release-activated calcium modulator 2) and ORAI3 (ORAI calcium release-activated calcium modulator 3). WB:WBGene00015649 C09F5.3 Predicted to enable chromatin insulator sequence binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome. WB:WBGene00015650 pkg-2 Predicted to enable ATP binding activity; cGMP binding activity; and cGMP-dependent protein kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in thoracic aortic aneurysm. Is an ortholog of human PRKG1 (protein kinase cGMP-dependent 1). WB:WBGene00015651 ceh-53 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in I5 neuron. Is an ortholog of human DMBX1 (diencephalon/mesencephalon homeobox 1). WB:WBGene00015652 srz-79 Predicted to be located in membrane. WB:WBGene00015653 srz-78 Predicted to be located in membrane. WB:WBGene00015654 srz-77 Is affected by several genes including sir-2.1; clk-1; and qui-1 based on microarray and RNA-seq studies. Is affected by Rifampin and Sirolimus based on RNA-seq studies. WB:WBGene00015655 C09G12.5 Expressed in vas deferens. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00015656 srz-70 Predicted to be located in membrane. WB:WBGene00015657 C09G12.7 No description available WB:WBGene00015658 tsg-101 Predicted to enable ubiquitin binding activity. Involved in endosome to lysosome transport via multivesicular body sorting pathway and receptor catabolic process. Located in endosome membrane. Part of ESCRT I complex. Expressed in head and tail. Human ortholog(s) of this gene implicated in breast carcinoma and reproductive organ cancer (multiple). Is an ortholog of human TSG101 (tumor susceptibility 101). WB:WBGene00015660 catp-3 Predicted to enable P-type sodium:potassium-exchanging transporter activity. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. Is an ortholog of human ATP12A (ATPase H+/K+ transporting non-gastric alpha2 subunit) and ATP4A (ATPase H+/K+ transporting subunit alpha). WB:WBGene00015661 C09H5.7 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00015662 C10A4.1 Predicted to enable protein dimerization activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human ZBED1 (zinc finger BED-type containing 1). WB:WBGene00015663 C10A4.2 Predicted to be located in membrane. WB:WBGene00015664 C10A4.3 Predicted to be located in membrane. WB:WBGene00015665 C10A4.4 Predicted to be located in membrane. WB:WBGene00015666 gad-2 Involved in gastrulation. Predicted to be located in membrane. WB:WBGene00015667 C10A4.6 Predicted to be located in membrane. WB:WBGene00015668 C10A4.7 Predicted to be located in membrane. WB:WBGene00015670 C10B5.1 Enriched in ABalpapaap; ABarappaap; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including aldicarb; allantoin; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: WD40 repeat; WD40/YVTN repeat-like-containing domain superfamily; WD40-repeat-containing domain superfamily; and WD domain, G-beta repeat. Is an ortholog of human GNB1L (G protein subunit beta 1 like). WB:WBGene00015671 C10B5.3 Enriched in several structures, including head mesodermal cell; interfacial epithelial cell; neurons; pm8; and spermatheca based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015672 C10E2.1 Enriched in AWAL; AWAR; neurons; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and bar-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Tunicamycin; Rifampin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00015673 C10E2.2 Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Is an ortholog of human FBXO40 (F-box protein 40). WB:WBGene00015675 C10E2.5 Predicted to be located in membrane. WB:WBGene00015676 mct-6 Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Expressed in tail. Human ortholog(s) of this gene implicated in cataract 47; familial hyperinsulinemic hypoglycemia 7; and lymphangioleiomyomatosis. Is an ortholog of several human genes including SLC16A1 (solute carrier family 16 member 1); SLC16A6 (solute carrier family 16 member 6); and SLC16A7 (solute carrier family 16 member 7). WB:WBGene00015677 cpg-4 Enriched in several structures, including RIH; amphid neurons; cholinergic neurons; germ line; and intestinal muscle based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by thirteen chemicals including manganese chloride; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Chondroitin proteoglycan 4. WB:WBGene00015678 mcp-1 Enables GDP-D-glucose phosphorylase activity. Involved in glucose metabolic process. Located in cytoplasm. Expressed in anterior hypodermis; nervous system; reproductive system; and spermatheca. Is an ortholog of human GDPGP1 (GDP-D-glucose phosphorylase 1). WB:WBGene00015679 C10F3.7 Enriched in arc ant V; head mesodermal cell; hyp1; hyp2; and seam cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including methylmercuric chloride; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00015680 egal-1 Predicted to enable 3'-5' exonuclease activity and nucleic acid binding activity. Predicted to be involved in piRNA processing. Predicted to be located in nuclear envelope. Predicted to be part of PET complex. Is an ortholog of human EXD1 (exonuclease 3'-5' domain containing 1). WB:WBGene00015681 C10G8.2 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00015682 C10G8.3 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00015683 C10G8.4 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00015684 C10G8.8 Expressed in tail. Human CCDC9 enables RNA binding activity. Is predicted to encode a protein with the following domain: Phosphorylation site. Is an ortholog of human CCDC9 (coiled-coil domain containing 9) and CCDC9B (coiled-coil domain containing 9B). WB:WBGene00015685 C10G11.1 Predicted to be located in membrane. WB:WBGene00015686 C10G11.6 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including hsf-1; pgl-1; and hsp-6 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; Aspirin; and Alovudine based on RNA-seq studies. WB:WBGene00015687 chdp-1 Expressed in several structures, including neurons. Is predicted to encode a protein with the following domains: Calponin homology (CH) domain; Calponin homology domain; CH domain superfamily; and Phosphorylation site. WB:WBGene00015688 C10G11.8 Predicted to enable proteasome-activating activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of proteasome regulatory particle, base subcomplex. WB:WBGene00015689 spch-2 Part of chromatin. Expressed in sperm. WB:WBGene00015690 C10G11.10 Predicted to be located in membrane. WB:WBGene00015691 viln-1 Predicted to enable actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in actin filament severing; actin polymerization or depolymerization; and barbed-end actin filament capping. Predicted to be located in actin cytoskeleton and cytoplasm. Expressed in head and tail. Human ortholog(s) of this gene implicated in myofibrillar myopathy 10. Is an ortholog of human SVIL (supervillin). WB:WBGene00015692 ugt-25 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B15 (UDP glucuronosyltransferase family 2 member B15); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00015693 ugt-28 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00015694 ugt-27 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00015695 ugt-26 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00015696 C10H11.7 Predicted to be located in cytoskeleton. WB:WBGene00015697 mlst-8 Involved in mesendoderm development. Predicted to be located in cytoplasm. Predicted to be part of TORC1 complex and TORC2 complex. Is an ortholog of human MLST8 (MTOR associated protein, LST8 homolog). WB:WBGene00015698 kca-1 Enables kinesin binding activity. Involved in embryo development; establishment of meiotic spindle localization; and polar body extrusion after meiotic divisions. Part of kinesin I complex. Expressed in gonad and oocyte. WB:WBGene00015700 asp-9 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Expressed in XXXL and XXXR. WB:WBGene00015701 C11D2.3 Enriched in several structures, including AFD; SMB; g2; mechanosensory neurons; and pharyngeal-intestinal valve cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including let-60; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including mianserin; stavudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00015702 C11D2.4 Predicted to be involved in tRNA-guanine transglycosylation. Is an ortholog of human QNG1 (Q-nucleotide N-glycosylase 1). WB:WBGene00015703 C11D2.7 Predicted to enable RNA binding activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to be located in cytoplasm. Is an ortholog of human MCTS2 (MCTS family member 2). WB:WBGene00015704 tiam-1 Enables guanyl-nucleotide exchange factor activity. Involved in small GTPase mediated signal transduction. Located in cell periphery and growth cone. Expressed in gonad and neurons. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with language delay and seizures. Is an ortholog of human TIAM2 (TIAM Rac1 associated GEF 2). WB:WBGene00015705 nhr-152 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head neurons; intestine; and pharynx. WB:WBGene00015706 C12D5.3 Enriched in ABplpaaaap; ABprpaaaap; head mesodermal cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and aak-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including D-glucose; Rifampin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015707 C12D5.4 Enriched in ABplpaaaaa; ABplpaaaap; ABprpaaaaa; ABprpaaaap; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and clk-1 based on microarray and RNA-seq studies. Is affected by tetrabromobisphenol A based on microarray studies. WB:WBGene00015708 C12D5.5 Enriched in neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; clk-1; and aak-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including Mercuric Chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00015709 cyp-33A1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). WB:WBGene00015710 C12D5.9 Enriched in amphid sheath cell; male-specific anatomical entity; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00015711 C12D5.10 Enriched in AMshL; AMshR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; daf-18; and isp-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube; antimycin; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00015712 sre-11 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00015713 C12D12.1 Enriched in OLL; PVD; germ line; head mesodermal cell; and intestine based on proteomic; microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-three chemicals including methylmercuric chloride; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00015714 C12D12.3 Predicted to be located in membrane. WB:WBGene00015716 sox-4 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in innate immune response. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including Coffin-Siris syndrome (multiple); gonadal dysgenesis (multiple); and hypotrichosis-lymphedema-telangiectasia syndrome. Is an ortholog of several human genes including SOX11 (SRY-box transcription factor 11); SOX15 (SRY-box transcription factor 15); and SOX4 (SRY-box transcription factor 4). WB:WBGene00015717 C12D12.6 No description available WB:WBGene00015718 C13A2.1 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00015719 C13A2.2 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; daf-12; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by tryptophan based on microarray studies. WB:WBGene00015720 C13A2.3 Predicted to be located in membrane. WB:WBGene00015721 C13A2.4 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00015722 C13A2.5 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00015723 C13A2.6 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00015724 C13A2.7 Predicted to be located in membrane. WB:WBGene00015725 C13A2.9 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00015726 C13A2.10 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00015727 C13A2.11 Enriched in DA neuron; NSM; VA neuron; body wall muscle cell; and hypodermis based on tiling array studies. Is affected by rsr-2; mir-34; and sir-2.1 based on tiling array and microarray studies. Is affected by methylmercuric chloride based on microarray studies. WB:WBGene00015728 C13A10.1 Predicted to be located in membrane. WB:WBGene00015729 C13A10.2 Enriched in coelomocyte; head mesodermal cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; elt-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; 4-bromodiphenyl ether; and levamisole based on RNA-seq and microarray studies. WB:WBGene00015730 srt-1 Predicted to be located in membrane. WB:WBGene00015731 C13B7.6 Enriched in germ line; germline precursor cell; and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Sirolimus; Doxycycline; and Chlorpyrifos based on RNA-seq and microarray studies. WB:WBGene00015732 C13B9.1 No description available WB:WBGene00015733 C13B9.2 Predicted to enable glycerate kinase activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in D-glyceric aciduria. Is an ortholog of human GLYCTK (glycerate kinase). WB:WBGene00015734 copd-1 Predicted to be involved in Golgi localization; endoplasmic reticulum to Golgi vesicle-mediated transport; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be part of COPI vesicle coat. Is an ortholog of human ARCN1 (archain 1). WB:WBGene00015735 pdfr-1 Enables calcitonin family receptor activity. Involved in several processes, including locomotory behavior; signal transduction; and sleep. Located in plasma membrane. Expressed in several structures, including I1 neuron; RMEV; ganglia; mechanosensory neurons; and vulD. Human ortholog(s) of this gene implicated in bone disease (multiple); hereditary lymphedema; and primary failure of tooth eruption. Is an ortholog of human CALCR (calcitonin receptor); CALCRL (calcitonin receptor like receptor); and PTH1R (parathyroid hormone 1 receptor). WB:WBGene00015736 srsx-11 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00015737 srsx-12 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in AVG; PVT; head neurons; and vulval muscle. WB:WBGene00015738 srsx-13 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00015739 ugt-7 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00015740 C13E3.1 Enriched in several structures, including MSpppaaa; XXX cell; head mesodermal cell; intestinal muscle; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by six chemicals including stavudine; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00015741 C13F10.1 Predicted to be located in membrane and ribosome. WB:WBGene00015742 kxd-1 Predicted to be involved in lysosome localization. Predicted to be part of BORC complex. Is an ortholog of human KXD1 (KxDL motif containing 1). WB:WBGene00015743 soap-1 Involved in apical protein localization. Predicted to be located in endocytic vesicle. Is an ortholog of human HEATR5A (HEAT repeat containing 5A) and HEATR5B (HEAT repeat containing 5B). WB:WBGene00015744 C13F10.5 Predicted to be located in membrane. Is an ortholog of human SAYSD1 (SAYSVFN motif domain containing 1). WB:WBGene00015745 C13F10.6 Enriched in several structures, including cephalic sheath cell; ciliated neurons; germ line; pharyngeal cell; and rectal epithelial cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including dpy-10; hsf-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00015746 C13F10.7 Enables identical protein binding activity. Is an ortholog of human SREK1IP1 (SREK1 interacting protein 1). WB:WBGene00015747 C13G5.2 Enriched in germ line; germline precursor cell; head neurons; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015748 C14A11.2 Enriched in excretory gland cell; head mesodermal cell; neurons; pharyngeal muscle cell; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00015750 C14A11.5 Enriched in excretory gland cell; head mesodermal cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00015751 C14A11.6 Enriched in neurons and rect_D based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015752 C14B9.2 Predicted to enable protein disulfide isomerase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in cell surface and endoplasmic reticulum. Is an ortholog of human PDIA4 (protein disulfide isomerase family A member 4). WB:WBGene00015753 C14B9.3 Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00015754 C14B9.8 Predicted to enable calmodulin binding activity. Predicted to be involved in glycogen metabolic process. Predicted to be located in plasma membrane. Predicted to be part of phosphorylase kinase complex. Human ortholog(s) of this gene implicated in glycogen storage disease IXa and glycogen storage disease IXd. Is an ortholog of human PHKA1 (phosphorylase kinase regulatory subunit alpha 1) and PHKA2 (phosphorylase kinase regulatory subunit alpha 2). WB:WBGene00015755 C14B9.10 Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex III. Is an ortholog of human UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X). WB:WBGene00015756 C14C6.2 Enriched in OLL; PVD; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; D-glucopyranose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00015757 C14C6.3 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. Expressed in seam cell. WB:WBGene00015758 nhr-155 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00015759 C14C6.5 Involved in innate immune response. WB:WBGene00015760 C14C6.6 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00015761 C14C6.7 Is affected by several genes including daf-2; isp-1; and unc-30 based on tiling array; RNA-seq; and microarray studies. Is affected by cadmium based on microarray studies. WB:WBGene00015762 C14C6.8 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00015763 C14C6.12 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including copper sulfate; Zidovudine; and allantoin based on microarray and RNA-seq studies. WB:WBGene00015764 C14C6.13 Enriched in neurons based on RNA-seq studies. Is affected by several genes including clk-1; drh-3; and mir-34 based on tiling array; microarray; and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00015765 C14C11.1 Enriched in PLM; germ line; hypodermis; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Ethanol; methylmercuric chloride; and mianserin based on RNA-seq and microarray studies. WB:WBGene00015766 C14C11.2 Enriched in several structures, including germ line; germline precursor cell; male distal tip cell; rectal epithelium; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including rotenone; bisphenol A; and bisphenol S based on RNA-seq studies. WB:WBGene00015767 hex-2 Enables beta-N-acetylgalactosaminidase activity. Involved in polysaccharide metabolic process. Expressed in head neurons; hypodermis; tail neurons; and vulva. Is an ortholog of human HEXD (hexosaminidase D). WB:WBGene00015768 C14C11.4 Predicted to be involved in innate immune response. Predicted to be located in membrane. WB:WBGene00015769 C14C11.7 Enriched in AFD; PLM; germ line; pharyngeal muscle cell; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; tryptophan; and rotenone based on microarray and RNA-seq studies. WB:WBGene00015770 C14E2.1 Enriched in ASIL; ASIR; and body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including rde-1; rrf-1; and mex-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015771 got-1.3 Enriched in AVE based on tiling array studies. Is affected by several genes including eat-2; mex-3; and set-2 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00015772 C14E2.3 Enriched in neurons based on RNA-seq studies. Is affected by several genes including lin-4; eat-2; and lin-14 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00015773 C14E2.4 Predicted to enable procollagen-proline 4-dioxygenase activity. Predicted to be located in endoplasmic reticulum. WB:WBGene00015774 C14E2.5 Predicted to be located in membrane. WB:WBGene00015775 C14E2.6 Predicted to be involved in lipid metabolic process. WB:WBGene00015776 dct-1 Enables protease binding activity and protein homodimerization activity. Involved in several processes, including apoptotic process; autophagy of mitochondrion; and determination of adult lifespan. Located in mitochondrial outer membrane and protein-containing complex. Expressed in body wall musculature; intestine; pharynx; and vulval muscle. Human ortholog(s) of this gene implicated in ductal carcinoma in situ and perinatal necrotizing enterocolitis. Is an ortholog of human BNIP3 (BCL2 interacting protein 3). WB:WBGene00015777 sfxn-2 Predicted to enable serine transmembrane transporter activity. Predicted to be involved in serine import into mitochondrion. Predicted to be located in mitochondrial membrane. Is an ortholog of human SFXN2 (sideroflexin 2). WB:WBGene00015778 got-2.2 Predicted to enable L-aspartate:2-oxoglutarate aminotransferase activity. Predicted to be involved in aspartate catabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 82. Is an ortholog of human GOT2 (glutamic-oxaloacetic transaminase 2). WB:WBGene00015779 lrch-1 Predicted to be involved in signal transduction. Is an ortholog of several human genes including LRCH1 (leucine rich repeats and calponin homology domain containing 1); LRCH2 (leucine rich repeats and calponin homology domain containing 2); and LRCH4 (leucine rich repeats and calponin homology domain containing 4). WB:WBGene00015780 C14F11.4 Enriched in anterior spermatheca; coelomocyte; germ line; intestine; and posterior spermatheca based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015781 rml-3 Predicted to enable racemase and epimerase activity. Predicted to be located in cytosol. WB:WBGene00015782 C14F11.7 Enriched in ABplppaaaap; ABprppaaaap; germ line; neurons; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Alovudine; stavudine; and allantoin based on RNA-seq studies. WB:WBGene00015783 C15B12.1 Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be located in peroxisome. Is an ortholog of human PIPOX (pipecolic acid and sarcosine oxidase). WB:WBGene00015784 C15B12.2 Predicted to be located in membrane. WB:WBGene00015785 C15B12.3 Enriched in coelomocyte based on tiling array studies. Is affected by several genes including cyc-1; mrps-5; and nhr-114 based on microarray; tiling array; and RNA-seq studies. WB:WBGene00015786 C15B12.4 Enriched in DVC; amphid sheath cell; body wall muscle cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by six chemicals including bisphenol A; paraquat; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00015787 actl-1 Enriched in AVK; DVA; NSM; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015788 C15B12.8 Predicted to enable L-pipecolate oxidase activity and sarcosine oxidase activity. Predicted to be involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Predicted to be located in peroxisome. Is an ortholog of human PIPOX (pipecolic acid and sarcosine oxidase). WB:WBGene00015789 syx-6 Predicted to be involved in synaptic vesicle docking. Located in Golgi trans cisterna. Expressed in head. Is an ortholog of human STX10 (syntaxin 10). WB:WBGene00015790 C15C7.4 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including aldicarb; multi-walled carbon nanotube; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00015791 bbln-1 Enables molecular adaptor activity. Involved in intermediate filament bundle assembly. Located in cell junction; intermediate filament; and subapical part of cell. Expressed in head neurons and pharyngeal muscle cell. WB:WBGene00015792 C15C7.6 Predicted to be located in membrane. WB:WBGene00015793 pfut-1 Enables peptide-O-fucosyltransferase activity. Involved in protein O-linked fucosylation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Dowling-Degos disease. Is an ortholog of human POFUT1 (protein O-fucosyltransferase 1). WB:WBGene00015794 C15F1.1 Enriched in PLM and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eighteen chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Human THAP4 enables several functions, including heme binding activity; identical protein binding activity; and peroxynitrite isomerase activity. Is predicted to encode a protein with the following domains: Calycin; THAP4-like, heme-binding beta-barrel domain; and Nitrobindin family. Is an ortholog of human THAP4 (THAP domain containing 4). WB:WBGene00015795 C15F1.2 Enriched in excretory system; head ganglion; male-specific anatomical entity; and mechanosensory neurons based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including Lithium Chloride; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00015796 C15F1.5 Predicted to enable metal ion binding activity. WB:WBGene00015797 C15F1.8 Predicted to be located in ribosome. WB:WBGene00015798 C15H9.2 Enriched in AIYL; AIYR; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; tert-Butylhydroperoxide; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00015799 C15H9.3 Predicted to be located in membrane. WB:WBGene00015800 C15H9.4 Predicted to be located in endomembrane system. Is an ortholog of human TMCC1 (transmembrane and coiled-coil domain family 1). WB:WBGene00015801 C15H9.5 Predicted to be located in Golgi apparatus and membrane. Is an ortholog of human GPR108 (G protein-coupled receptor 108). WB:WBGene00015802 kynu-1 Predicted to enable kynureninase activity. Predicted to be involved in anthranilate metabolic process and tryptophan catabolic process to kynurenine. Predicted to be located in cytoplasm. Expressed in E lineage cell and hypodermal cell. Human ortholog(s) of this gene implicated in hydroxykynureninuria. Is an ortholog of human KYNU (kynureninase). WB:WBGene00015803 C15H9.9 Expressed in marginal cell. WB:WBGene00015805 C15H9.11 Enriched in GABAergic neurons; arcade cell; pharyngeal-intestinal valve; and rectal gland cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including methylmercuric chloride; rotenone; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00015806 smrc-1 Predicted to enable ATP-dependent DNA/DNA annealing activity. Predicted to be involved in DNA repair; regulation of transcription by RNA polymerase II; and replication fork processing. Predicted to be located in nuclear replication fork. Expressed in male. Human ortholog(s) of this gene implicated in Schimke immuno-osseous dysplasia. Is an ortholog of human SMARCAL1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1). WB:WBGene00015807 C16A3.2 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in dephosphorylation and signal transduction. Predicted to be located in cytosol. Is an ortholog of human DUSP22 (dual specificity phosphatase 22). WB:WBGene00015809 znf-622 Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in cytoplasm. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human ZNF622 (zinc finger protein 622). WB:WBGene00015810 C16A3.5 Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 24. Is an ortholog of human NDUFB9 (NADH:ubiquinone oxidoreductase subunit B9). WB:WBGene00015811 C16A3.6 Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be located in nucleolus. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human MAK16 (MAK16 homolog). WB:WBGene00015813 thoc-2 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Predicted to be part of THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in X-linked intellectual disability-short stature-overweight syndrome. Is an ortholog of human THOC2 (THO complex subunit 2). WB:WBGene00015814 oatr-1 Predicted to enable identical protein binding activity; ornithine-oxo-acid transaminase activity; and pyridoxal phosphate binding activity. Predicted to be involved in arginine catabolic process to glutamate and arginine catabolic process to proline via ornithine. Predicted to be located in cytoplasm. Expressed in tail. Used to study amino acid metabolic disorder. Human ortholog(s) of this gene implicated in gyrate atrophy. Is an ortholog of human OAT (ornithine aminotransferase). WB:WBGene00015815 C16A11.2 Predicted to be involved in Golgi to plasma membrane transport. Is an ortholog of human CCDC93 (coiled-coil domain containing 93). WB:WBGene00015816 C16A11.3 Predicted to enable metal ion binding activity. WB:WBGene00015817 C16A11.4 Predicted to enable metal ion binding activity. WB:WBGene00015818 C16A11.5 Predicted to be involved in innate immune response. WB:WBGene00015819 fbxc-44 Enriched in several structures, including ADE sheath cell; AFD; RIC; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF3557. WB:WBGene00015820 C16A11.7 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00015821 clec-135 Enriched in neurons based on RNA-seq studies. Is affected by several genes including let-60; eat-2; and tph-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Alovudine; stavudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C-type lectin fold. WB:WBGene00015822 C16B8.2 Enriched in anterior ganglion (ant); anterior hypodermis; arc ant V; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Mercuric Chloride; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Growth factor receptor cysteine-rich domain superfamily. WB:WBGene00015823 C16B8.3 Enriched in head mesodermal cell; intestine; mechanosensory neurons; pharyngeal muscle cell; and rectal gland cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015824 C16B8.4 Predicted to be located in membrane. Expressed in AIYL and AIYR. WB:WBGene00015825 C16C4.1 Enriched in dopaminergic neurons; excretory gland cell; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by rsr-2 and klf-1 based on tiling array and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00015826 math-12 Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00015827 math-13 Is affected by lin-14 and lin-4 based on microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015828 math-14 Enriched in intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Heme; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015829 math-15 Enriched in NSM; intestine; mechanosensory neurons; and nerve ring neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including aldicarb; multi-walled carbon nanotube; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015830 fbxb-98 Predicted to be located in membrane. WB:WBGene00015832 math-16 Is affected by several genes including skn-1; clk-1; and smn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015833 math-17 Is affected by several genes including skn-1; sir-2.1; and lin-35 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00015834 math-5 Is affected by several genes including skn-1; lin-35; and nhr-49 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015835 math-6 Is affected by several genes including skn-1; sir-2.1; and lin-35 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015836 math-7 Is affected by several genes including eat-2; pgl-1; and prg-1 based on RNA-seq and tiling array studies. Is affected by five chemicals including aldicarb; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015837 math-8 Is affected by several genes including daf-2; eat-2; and alg-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Cadmium Chloride; Alovudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015838 math-9 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015839 math-10 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including tryptophan; Tunicamycin; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00015840 math-11 Is affected by several genes including lin-4; lin-14; and clk-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00015841 skpo-2 Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in extracellular space. WB:WBGene00015842 C16C8.4 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to be part of cytosolic small ribosomal subunit. WB:WBGene00015843 C16C8.5 Enriched in germ line; germline precursor cell; head mesodermal cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including hsf-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Ubiquitin-like domain superfamily and Ubiquitin-like domain. WB:WBGene00015844 C16C8.6 No description available WB:WBGene00015845 C16C8.7 Enriched in PLML; PLMR; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies. WB:WBGene00015846 C16C8.8 Enriched in germ line; male-specific anatomical entity; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including rrf-3; tph-1; and cat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015847 C16C8.9 Enriched in AVE; germ line; male-specific anatomical entity; and in male based on proteomic; tiling array; RNA-seq; and microarray studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including Alovudine; stavudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00015848 C16C8.10 Enriched in ABplpaaaap; ABprpaaaap; male-specific anatomical entity; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015849 C16C8.11 Enriched in AFD; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including manganese chloride; Zidovudine; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ubiquitin-like domain superfamily; Ubiquitin-like domain; and Ubiquitin family. WB:WBGene00015850 C16C8.12 Enriched in germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; mianserin; and stavudine based on RNA-seq and microarray studies. WB:WBGene00015851 gldi-6 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on proteomic; microarray; and RNA-seq studies. Is affected by twelve chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015852 C16C8.14 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to be part of cytosolic small ribosomal subunit. WB:WBGene00015853 C16C8.16 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to be part of cytosolic small ribosomal subunit. WB:WBGene00015854 C16C8.17 Enriched in ABaraapapp; ABaraapppp; germ line; male-specific anatomical entity; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including allantoin; Psoralens; and metformin based on RNA-seq and microarray studies. WB:WBGene00015855 C16C8.18 Predicted to enable microtubule binding activity. Predicted to be located in mitochondrion; mitotic spindle pole; and spindle microtubule. WB:WBGene00015856 C16C8.19 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Alovudine; stavudine; and allantoin based on RNA-seq studies. WB:WBGene00015857 C16D9.1 Enriched in hyp1 and hyp2 based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including nicotinic acid; rotenone; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00015858 C16D9.3 Enriched in AVA and neurons based on tiling array and RNA-seq studies. Is affected by several genes including sek-1; pgl-1; and glh-1 based on tiling array and RNA-seq studies. Is affected by five chemicals including Sodium Chloride; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00015859 C16D9.4 Enriched in head mesodermal cell and intestine based on tiling array and RNA-seq studies. Is affected by several genes including dpy-10; npr-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including aldicarb; diallyl trisulfide; and D-glucopyranose based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1647); Protein of unknown function DUF1647; and Phosphorylation site. WB:WBGene00015860 C16D9.5 Enriched in ABplpppaapa; ABprpppaapa; g1; neurons; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and rde-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1647); Protein of unknown function DUF1647; and Phosphorylation site. WB:WBGene00015861 C16D9.6 Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Tn polyagglutination syndrome. Is an ortholog of human C1GALT1C1 (C1GALT1 specific chaperone 1). WB:WBGene00015862 srt-25 Enriched in neurons and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including clk-1; hpl-2; and dpy-21 based on tiling array; microarray; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00015863 C16D9.8 Enriched in ADLL and ADLR based on single-cell RNA-seq studies. Is affected by several genes including sir-2.1; csr-1; and set-2 based on microarray and RNA-seq studies. Is affected by four chemicals including aldicarb; resveratrol; and Chlorpyrifos based on microarray studies. WB:WBGene00015864 C16D9.9 Enriched in neurons and ventral nerve cord based on tiling array; single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including daf-16; elt-2; and clk-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Tunicamycin; Cadmium Chloride; and paraquat based on microarray and RNA-seq studies. WB:WBGene00015865 C16E9.1 Predicted to be an extracellular matrix structural constituent. Predicted to be involved in extracellular matrix organization. Predicted to be located in collagen-containing extracellular matrix. Is an ortholog of human MATN1 (matrilin 1). WB:WBGene00015866 C16E9.2 Expressed in hypodermal cell; muscle cell; and nervous system. Is predicted to encode a protein with the following domains: Uncharacterized conserved protein (DUF2045); Protein of unknown function DUF2045; and Phosphorylation site. Is an ortholog of human KIAA0930 (KIAA0930). WB:WBGene00015867 ncs-7 Predicted to enable calcium ion binding activity. Expressed in neurons and vulval muscle. Is an ortholog of human KCNIP1 (potassium voltage-gated channel interacting protein 1). WB:WBGene00015868 C16H3.3 Enriched in intestine; neurons; and retrovesicular ganglion based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including 1-methylnicotinamide; rotenone; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015869 nhr-257 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00015870 C17A2.2 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00015871 C17A2.3 Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be located in membrane. WB:WBGene00015872 C17A2.4 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00015873 oac-4 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00015874 C17A2.6 Is affected by several genes including eat-2; clk-1; and dpy-21 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015875 C17A2.7 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00015876 C17B7.2 Enriched in PLM and body wall muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including manganese chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015877 C17B7.3 Enriched in body wall muscle cell and hypodermis based on tiling array studies. Is affected by several genes including eat-2; sir-2.1; and sek-1 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; indole; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00015878 C17B7.4 Enriched in body wall muscle cell and muscle cell based on tiling array and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Ethanol; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00015879 C17B7.5 Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Predicted to be involved in glycoprotein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Predicted to be located in cytosol and nucleus. WB:WBGene00015881 C17B7.7 No description available WB:WBGene00015882 C17B7.8 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00015883 C17B7.9 Enriched in ABplaapappp; ABpraapappp; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including resveratrol; Atrazine; and Chlorpyrifos based on microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00015884 C17B7.10 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on RNA-seq and microarray studies. Is affected by six chemicals including methylmercuric chloride; Mercuric Chloride; and tert-Butylhydroperoxide based on microarray and RNA-seq studies. WB:WBGene00015885 fbxa-65 Enriched in several structures, including arcade cell; coelomocyte; intestine; mechanosensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by nine chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00015886 C17B7.12 Enriched in neurons based on tiling array studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; Ethanol; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00015887 C17C3.1 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid catabolic process. Predicted to be located in peroxisomal matrix. Is an ortholog of human ACOT8 (acyl-CoA thioesterase 8). WB:WBGene00015888 C17C3.2 Is affected by rsr-2; dlc-1; and csr-1 based on tiling array and RNA-seq studies. Is affected by aldicarb; fluoranthene; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domain: Papain-like cysteine peptidase superfamily. WB:WBGene00015889 C17C3.3 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid catabolic process. Predicted to be located in peroxisomal matrix. Is an ortholog of human ACOT8 (acyl-CoA thioesterase 8). WB:WBGene00015890 C17C3.5 Enriched in several structures, including ABalapapapa; ABalapppaa; ABalapppapa; ABplpaaappa; and ABprpaaappa based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seventeen chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00015891 C17C3.6 Is affected by several genes including hsp-6; unc-30; and csr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Rifampin; antimycin; and Doxycycline based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily and F-box domain. WB:WBGene00015892 C17C3.9 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including tryptophan; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00015893 C17C3.11 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00015894 acdh-2 Predicted to enable acyl-CoA dehydrogenase activity. Predicted to be located in mitochondrion. Expressed in body wall musculature; hypodermis; intestine; and muscle cell. Is an ortholog of human ACADSB (acyl-CoA dehydrogenase short/branched chain). WB:WBGene00015895 C17C3.13 Is affected by several genes including clk-1; csr-1; and dlc-1 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domain: Papain-like cysteine peptidase superfamily. WB:WBGene00015896 C17C3.15 Enriched in RIBL; RIBR; and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; sodium arsenite; and 4-bromodiphenyl ether based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00015897 nhr-156 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in excretory system; intestine; neurons; pharynx; and ventral nerve cord. WB:WBGene00015898 sre-9 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00015899 C17E7.4 Expressed in germ line. WB:WBGene00015900 nhr-157 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00015901 nhr-158 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00015902 nhr-159 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00015903 C17E7.9 Predicted to be located in membrane. WB:WBGene00015904 irld-22 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and isp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by dafa#1 based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00015905 C17E7.12 Predicted to be located in membrane. WB:WBGene00015906 C17E7.13 Predicted to be located in membrane. WB:WBGene00015907 C17F3.1 Predicted to be located in membrane. WB:WBGene00015908 C17F3.3 Enriched in AFD; germ line; and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Ethanol; methylmercuric chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00015909 clec-124 Enriched in intestine and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; lin-4; and lin-14 based on microarray and RNA-seq studies. Is affected by six chemicals including aldicarb; Zidovudine; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00015910 C17F4.2 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00015911 C17F4.3 Enriched in amphid sheath cell; hypodermis; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00015912 fbxc-50 Expressed in germ line. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00015913 C17F4.7 Enriched in cholinergic neurons; head mesodermal cell; intestine; pharyngeal cell; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty chemicals including cholesterol; lathosterol; and Heme based on microarray and RNA-seq studies. WB:WBGene00015914 C17F4.8 Predicted to be involved in protein homooligomerization. Is an ortholog of human KCTD10 (potassium channel tetramerization domain containing 10) and TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00015915 C17G10.1 Predicted to enable peptidyl-proline dioxygenase activity. Predicted to be involved in regulation of translational termination. Predicted to be located in cytoplasm. Expressed in hypodermis. Is an ortholog of human OGFOD1 (2-oxoglutarate and iron dependent oxygenase domain containing 1). WB:WBGene00015916 ttc-4 Predicted to enable Hsp70 protein binding activity and Hsp90 protein binding activity. Predicted to be involved in protein folding. Predicted to be located in nucleus. Expressed in head. Is an ortholog of human TTC4 (tetratricopeptide repeat domain 4). WB:WBGene00015917 C17G10.3 Enriched in several structures, including ABaraapapaa; ABaraapppaa; germ line; neurons; and rect_D based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including manganese chloride; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015918 C17G10.6 Enriched in XXXL and XXXR based on single-cell RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; Sodium Chloride; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: ShKT domain. WB:WBGene00015919 C17G10.7 Predicted to be located in membrane. WB:WBGene00015920 eif-3.L Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Expressed in head and tail. Is an ortholog of human EIF3L (eukaryotic translation initiation factor 3 subunit L). WB:WBGene00015921 C17H11.1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00015922 C17H11.2 Enriched in several structures, including ABalppppppa; ABplaapapa; ABplaapappp; rectal epithelium; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; sir-2.1; and pgl-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by Zidovudine; paraquat; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00015923 C17H11.3 No description available WB:WBGene00015924 C17H11.4 Enriched in AB and germ line based on RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and sir-2.1 based on microarray and RNA-seq studies. Is affected by dafa#1 and Sirolimus based on microarray studies. Human ARIH1 enables enzyme binding activity; ubiquitin-protein transferase activity; and zinc ion binding activity. Is an ortholog of human ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1). WB:WBGene00015925 C17H11.5 Enriched in g2; neurons; and pharyngeal-intestinal valve based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including clk-1; aak-2; and lin-15B based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; bisphenol A; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015926 C17H11.6 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of ubiquitin ligase complex. Expressed in tail. Is an ortholog of human RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase) and RNF19B (ring finger protein 19B). WB:WBGene00015927 dyci-1 Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in transport along microtubule. Predicted to be part of cytoplasmic dynein complex. Expressed in ciliated neurons. Is an ortholog of human DYNC1I1 (dynein cytoplasmic 1 intermediate chain 1) and DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2). WB:WBGene00015928 C17H12.2 Predicted to be located in membrane. Expressed in gonad. Is an ortholog of human KIAA2013 (KIAA2013). WB:WBGene00015929 C17H12.3 Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of human PTPN7 (protein tyrosine phosphatase non-receptor type 7). WB:WBGene00015930 cest-4 Predicted to be located in membrane. WB:WBGene00015931 C17H12.5 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00015932 C17H12.6 Involved in innate immune response. WB:WBGene00015933 C17H12.8 Predicted to be involved in innate immune response. WB:WBGene00015934 ceh-48 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head; neurons; spermathecal-uterine junction; ventral nerve cord; and vulva. Is an ortholog of human ONECUT1 (one cut homeobox 1); ONECUT2 (one cut homeobox 2); and ONECUT3 (one cut homeobox 3). WB:WBGene00015935 C17H12.10 Predicted to be located in membrane. WB:WBGene00015936 C17H12.11 Enriched in RIR; hypodermis; and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00015937 C17H12.12 Enriched in several structures, including ABplaapaaa; ABpraapaaa; AVK; germ line; and head neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-six chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00015938 anat-1 Predicted to enable N-acetyltransferase activity. WB:WBGene00015939 damt-1 Enables site-specific DNA-methyltransferase (adenine-specific) activity. Involved in epigenetic regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of RNA N6-methyladenosine methyltransferase complex. Is an ortholog of human METTL4 (methyltransferase 4, N6-adenosine). WB:WBGene00015940 zipt-3 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human SLC39A3 (solute carrier family 39 member 3). WB:WBGene00015941 C18A3.3 Predicted to be involved in rRNA processing and ribosomal large subunit biogenesis. Predicted to be located in nuclear periphery and nucleolus. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human EBNA1BP2 (EBNA1 binding protein 2). WB:WBGene00015942 osta-2 Predicted to be located in membrane. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Is an ortholog of human SLC51A (solute carrier family 51 subunit alpha). WB:WBGene00015943 tiar-1 Predicted to enable mRNA binding activity. Involved in several processes, including determination of adult lifespan; nematode larval development; and response to UV. Located in P granule; cytoplasmic stress granule; and nucleus. Expressed in several structures, including germ line; hypodermis; mechanosensory neurons; somatic cell; and tail. Is an ortholog of human TIA1 (TIA1 cytotoxic granule associated RNA binding protein) and TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1). WB:WBGene00015944 C18A3.7 Enriched in several structures, including ABplpapppa; ABprpapppa; AFD; MSpaaaaa; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00015945 lelo-4 Predicted to be located in membrane. WB:WBGene00015946 C18A3.10 Predicted to be located in membrane. WB:WBGene00015947 C18A11.1 Enriched in several structures, including amphid sheath cell; coelomocyte; dopaminergic neurons; head mesodermal cell; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-three chemicals including 1-methylnicotinamide; methylmercuric chloride; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00015948 C18A11.2 Enriched in anterior arcade cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; clk-1; and lin-35 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; D-glucose; and metformin based on RNA-seq and microarray studies. WB:WBGene00015949 C18A11.3 Predicted to be located in membrane. WB:WBGene00015950 C18A11.4 Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including tryptophan; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: SH2 domain superfamily. WB:WBGene00015952 vep-2 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00015953 C18B2.2 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00015954 C18B2.3 Expressed in anal depressor muscle; body wall musculature; and vulval muscle. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015955 C18B2.4 Predicted to enable chromatin DNA binding activity and transcription coactivator activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 107. Is an ortholog of human WBP2 (WW domain binding protein 2). WB:WBGene00015956 C18B2.5 Predicted to enable GTPase activity and molecular adaptor activity. Predicted to be involved in cytoskeleton-dependent cytokinesis and regulation of exocytosis. Predicted to be located in cell division site; cytoskeleton; and synaptic vesicle. Predicted to be part of septin complex. WB:WBGene00015957 del-9 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00015958 srbc-11 Predicted to be located in membrane. WB:WBGene00015959 srbc-10 Predicted to be located in membrane. WB:WBGene00015960 srbc-9 Predicted to be located in membrane. WB:WBGene00015961 srbc-7 Predicted to be located in membrane. Expressed in ASJL and ASJR. WB:WBGene00015962 srbc-8 Predicted to be located in membrane. WB:WBGene00015963 C18B10.6 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00015964 glb-5 Enables oxygen sensor activity. Involved in detection of oxygen. Expressed in PQR; head neurons; intestine; pharynx; and somatic nervous system. WB:WBGene00015965 ugt-48 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00015968 C18C4.7 Enriched in coelomocyte; interfacial epithelial cell; male-specific anatomical entity; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq; proteomic; and microarray studies. WB:WBGene00015969 glb-6 Enables heme binding activity; iron ion binding activity; and oxygen binding activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in neurons and somatic nervous system. WB:WBGene00015970 C18E3.1 Enriched in several structures, including B cell; Z1.p; Z4.a; germ line; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by eight chemicals including Rifampin; allantoin; and antimycin based on RNA-seq and microarray studies. WB:WBGene00015971 swsn-2.2 Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in condensed chromosome; nuclear envelope; and nucleoplasm. Expressed in several structures, including HSNL and HSNR. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 11. Is an ortholog of human SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1); SMARCD2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2); and SMARCD3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3). WB:WBGene00015972 C18E3.3 Enriched in several structures, including ABplapaaaap; germ line; male distal tip cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015974 snrp-40.2 Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human SNRNP40 (small nuclear ribonucleoprotein U5 subunit 40). WB:WBGene00015975 cas-2 Enables adenyl-nucleotide exchange factor activity. Involved in regulation of actin filament polymerization. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CAP1 (cyclase associated actin cytoskeleton regulatory protein 1) and CAP2 (cyclase associated actin cytoskeleton regulatory protein 2). WB:WBGene00015976 melo-2 Enriched in several structures, including ADE sheath cell; AFD; CAN; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including rotenone; manganese chloride; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00015977 C18F10.2 Enriched in neurons and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; pgl-1; and aak-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including tryptophan; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00015978 C18F10.7 Predicted to be located in cytoplasm. Is an ortholog of human ANKRD13B (ankyrin repeat domain 13B). WB:WBGene00015979 C18F10.9 Is affected by rsr-2 and drh-3 based on tiling array and RNA-seq studies. WB:WBGene00015980 C18G1.1 Predicted to be located in membrane. WB:WBGene00015981 elt-7 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endodermal cell fate determination. Located in nucleus. Expressed in E lineage cell. WB:WBGene00015982 bgnt-1.4 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A13. Is an ortholog of human B4GAT1 (beta-1,4-glucuronyltransferase 1). WB:WBGene00015984 C18G1.6 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00015985 C18G1.7 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00015986 C18G1.8 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00015987 C18G1.9 Enriched in NSM; germ line; and in male based on RNA-seq and tiling array studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-three chemicals including aldicarb; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00015988 lido-18 Predicted to be located in membrane. WB:WBGene00015989 C18H2.2 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Zidovudine; metformin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00015990 C18H2.3 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; methylmercury hydroxide; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00015991 C18H2.4 Enriched in germ line; neurons; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; metformin; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00015992 C18H2.5 Predicted to be located in membrane. WB:WBGene00015993 C18H7.1 Predicted to be an extracellular matrix structural constituent. Predicted to be involved in extracellular matrix organization. Predicted to be located in collagen-containing extracellular matrix. WB:WBGene00015994 C18H7.4 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00015996 C18H7.6 Predicted to be located in membrane. WB:WBGene00015997 C18H7.7 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00015998 srt-59 Predicted to be located in membrane. WB:WBGene00015999 prmt-4 Predicted to enable hexaprenyldihydroxybenzoate methyltransferase activity. Predicted to be involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. WB:WBGene00016000 C18H9.1 Enriched in pm6 based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; clk-1; and nhr-49 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00016002 gyf-1 Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in Parkinson's disease. Is an ortholog of human GIGYF2 (GRB10 interacting GYF protein 2). WB:WBGene00016003 C18H9.5 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00016004 C18H9.6 Enriched in AVE; head mesodermal cell; intestine; mechanosensory neurons; and pharynx based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-nine chemicals including 1-methylnicotinamide; Mercuric Chloride; and rotenone based on RNA-seq; microarray; and proteomic studies. WB:WBGene00016005 ift-74 Predicted to enable beta-tubulin binding activity. Involved in chemotaxis; detection of stimulus involved in sensory perception; and intraciliary transport. Located in non-motile cilium. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 22; Joubert syndrome; and spermatogenic failure 58. Is an ortholog of human IFT74 (intraflagellar transport 74). WB:WBGene00016006 fln-2 Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization. Expressed in several structures, including anal depressor muscle; distal tip cell; excretory canal; hypodermis; and vulva. WB:WBGene00016008 C23F12.3 Enriched in PVT; rectal epithelial cell; sensory neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and csr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and antimycin based on RNA-seq and microarray studies. WB:WBGene00016009 C23F12.4 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppppapa; ABalppppppp; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Cry5B; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00016010 C23G10.1 Predicted to enable protein serine/threonine phosphatase activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in cytoplasm and nucleus. WB:WBGene00016011 C23G10.2 Predicted to enable deaminase activity. Predicted to be involved in organonitrogen compound catabolic process. Predicted to be located in cytosol and mitochondrion. Is an ortholog of human RIDA (reactive intermediate imine deaminase A homolog). WB:WBGene00016012 C23G10.5 Enriched in AFD; body wall muscle cell; muscle cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00016013 ugt-66 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00016014 C23G10.7 Predicted to enable tRNA (uracil) methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to be located in cytoplasm. Is an ortholog of human TRMT44 (tRNA methyltransferase 44 homolog). WB:WBGene00016015 sna-3 Expressed in several structures, including germ cell; somatic cell; and tail. Is predicted to encode a protein with the following domains: YbiA-like superfamily; NADAR domain; NADAR; and Phosphorylation site. WB:WBGene00016016 C23G10.10 Predicted to be located in membrane. WB:WBGene00016017 C23G10.11 Expressed in hypodermal cell. WB:WBGene00016018 C23H3.2 Predicted to be located in membrane. WB:WBGene00016019 ascc-1 Predicted to enable RNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Barrett's esophagus. Is an ortholog of human ASCC1 (activating signal cointegrator 1 complex subunit 1). WB:WBGene00016020 sptl-1 Predicted to enable serine C-palmitoyltransferase activity. Involved in establishment or maintenance of epithelial cell apical/basal polarity. Predicted to be located in endoplasmic reticulum. Expressed in head. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1A. Is an ortholog of human SPTLC1 (serine palmitoyltransferase long chain base subunit 1). WB:WBGene00016021 C23H3.5 Enriched in PLM; body wall muscle cell; germ line; muscle cell; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by five chemicals including paraquat; resveratrol; and Humic Substances based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF4477) and Nucleolus and neural progenitor protein-like, N-terminal domain. WB:WBGene00016022 C23H3.9 Enriched in several structures, including anterior arcade cell; interneuron; nerve ring neurons; pharynx; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including methylmercury hydroxide; Zidovudine; and allantoin based on RNA-seq and microarray studies. Human MBLAC1 enables RNA endonuclease activity and metal ion binding activity. Is predicted to encode a protein with the following domains: Metallo-beta-lactamase; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; and Metallo-beta-lactamase domain-containing protein 1. Is an ortholog of human MBLAC1 (metallo-beta-lactamase domain containing 1). WB:WBGene00016023 prmt-6 Predicted to enable hexaprenyldihydroxybenzoate methyltransferase activity. Predicted to be involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. WB:WBGene00016024 glb-7 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in head neurons and tail neurons. WB:WBGene00016025 xbx-4 Expressed in amphid neurons; ciliated neurons; head neurons; and sensory neurons. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF3719) and Protein of unknown function DUF3719. WB:WBGene00016027 C23H5.8 Enriched in AFD; OLL; PVD; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; proteomic; and microarray studies. Is affected by several genes including daf-16; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-nine chemicals including methylmercury hydroxide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00016028 flp-24 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. WB:WBGene00016029 elf-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in gonad development and regulation of cell division. Predicted to be located in nucleus. Expressed in head neurons and pharynx. Is an ortholog of human ELF1 (E74 like ETS transcription factor 1); ELF2 (E74 like ETS transcription factor 2); and ELF4 (E74 like ETS transcription factor 4). WB:WBGene00016030 sel-15 Predicted to enable protein kinase activity. Is an ortholog of human FPGT-TNNI3K (FPGT-TNNI3K readthrough) and TNNI3K (TNNI3 interacting kinase). WB:WBGene00016031 C24A1.4 No description available WB:WBGene00016032 C24A3.1 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sek-1; pgl-1; and alg-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Coiled-coil domain-containing protein 154. Is an ortholog of human CCDC154 (coiled-coil domain containing 154). WB:WBGene00016033 C24A3.2 Located in plasma membrane. WB:WBGene00016034 C24A3.4 Predicted to enable alpha-methylacyl-CoA racemase activity. Predicted to be involved in bile acid metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including alpha-methylacyl-CoA racemase deficiency; congenital bile acid synthesis defect 4; and urinary system cancer (multiple). Is an ortholog of human AMACR (alpha-methylacyl-CoA racemase). WB:WBGene00016035 C24A3.7 No description available WB:WBGene00016037 dop-6 Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; chemical synaptic transmission; and dopamine receptor signaling pathway. Predicted to be located in dendrite. Expressed in several structures, including AVF; SMDVL; head neurons; intestine; and lumbar neurons. WB:WBGene00016038 cst-2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and regulation of MAPK cascade. Predicted to be located in cytoplasm. Expressed in AQR and PQR. Is an ortholog of human STK3 (serine/threonine kinase 3). WB:WBGene00016039 C24A8.5 Enriched in AIY; germ line; muscle cell; and touch receptor neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016040 C24A11.1 Enriched in several structures, including AVG; RIM; command interneuron; germ line; and sperm based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00016044 C24B5.1 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00016045 spas-1 Enables several functions, including ATP binding activity; ATP hydrolysis activity; and microtubule severing ATPase activity. Involved in several processes, including microtubule cytoskeleton organization; positive regulation of microtubule depolymerization; and vulval development. Located in microtubule cytoskeleton; perinuclear region of cytoplasm; and protein-containing complex. Expressed in several structures, including intestine; mechanosensory neurons; somatic nervous system; tail ganglion; and vulva. Used to study hereditary spastic paraplegia. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 4. Is an ortholog of human SPAST (spastin). WB:WBGene00016046 C24B5.4 Predicted to enable hydrolase activity, acting on ester bonds and zinc ion binding activity. Predicted to be located in nucleus. Expressed in body wall musculature. Is an ortholog of human C11orf54 (chromosome 11 open reading frame 54). WB:WBGene00016047 srt-26 Expressed in AWC-ON. WB:WBGene00016048 C24B9.3 Enriched in head mesodermal cell and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: von Willebrand factor A-like domain superfamily; von Willebrand factor, type A; and von Willebrand factor type A domain. WB:WBGene00016049 srt-28 Predicted to be located in membrane. Expressed in AWC-ON. WB:WBGene00016050 srt-29 Predicted to be located in membrane. Expressed in AWC-ON. WB:WBGene00016051 srt-27 Predicted to be located in membrane. Expressed in ASGL; ASGR; ASIL; and ASIR. WB:WBGene00016052 dod-3 Predicted to be located in membrane. WB:WBGene00016053 ptp-5.1 Predicted to enable protein tyrosine phosphatase activity. Located in nucleus. Expressed in head. WB:WBGene00016054 C24D10.2 Predicted to be located in membrane. WB:WBGene00016055 C24D10.4 Predicted to be located in membrane. WB:WBGene00016056 C24D10.5 Predicted to be located in membrane. WB:WBGene00016057 C24D10.6 Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion and nucleoplasm. Is an ortholog of human CHCHD1 (coiled-coil-helix-coiled-coil-helix domain containing 1). WB:WBGene00016058 nspd-3 Enriched in several structures, including amphid sheath cell; intestine; muscle cell; neurons; and sperm based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-seven chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Caenorhabditis elegans protein of unknown function (DUF780) and Protein of unknown function DUF780, Caenorhabditis species. WB:WBGene00016059 hir-1 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in cell periphery and membrane. Predicted to be part of receptor complex. Expressed in pharynx and seam cell. WB:WBGene00016060 mms-19 Predicted to be involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Predicted to be located in cytoplasm; nucleus; and spindle. Predicted to be part of CIA complex. Is an ortholog of human MMS19 (MMS19 homolog, cytosolic iron-sulfur assembly component). WB:WBGene00016061 hpo-15 Predicted to enable polyamine oxidase activity. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human PAOX (polyamine oxidase) and SMOX (spermine oxidase). WB:WBGene00016062 C24G6.8 Predicted to enable aminoacyl-tRNA hydrolase activity. Predicted to be located in cytosol and mitochondrion. Is an ortholog of human PTRH2 (peptidyl-tRNA hydrolase 2). WB:WBGene00016063 delm-2 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of human ASIC1 (acid sensing ion channel subunit 1); ASIC2 (acid sensing ion channel subunit 2); and ASIC3 (acid sensing ion channel subunit 3). WB:WBGene00016064 acd-1 Predicted to enable ligand-gated sodium channel activity. Involved in response to acidic pH and sodium ion transport. Predicted to be located in membrane. Expressed in AMshL and AMshR. Is an ortholog of human ASIC4 (acid sensing ion channel subunit family member 4). WB:WBGene00016065 C24G7.3 No description available WB:WBGene00016066 acd-2 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of human ASIC1 (acid sensing ion channel subunit 1); ASIC2 (acid sensing ion channel subunit 2); and ASIC3 (acid sensing ion channel subunit 3). WB:WBGene00016067 clc-7 Predicted to be located in membrane. WB:WBGene00016068 C24H10.2 Enriched in head neurons; intestine; muscle cell; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; sir-2.1; and lin-39 based on microarray and RNA-seq studies. Is affected by ten chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016069 C24H10.3 Enriched in several structures, including accessory cell; anterior hypodermis; male distal tip cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercury hydroxide; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00016070 C24H10.4 Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including clk-1; lin-35; and mex-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including hydrogen sulfide; Doxycycline; and dafa#1 based on microarray and RNA-seq studies. WB:WBGene00016071 C24H12.1 Predicted to be located in membrane. WB:WBGene00016072 C24H12.2 Enriched in several structures, including ABalaapppa; ABalaappppa; ABalapaapa; germ line; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by six chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016073 C24H12.4 Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be located in nucleolus. Is an ortholog of human DDX56 (DEAD-box helicase 56). WB:WBGene00016074 dnsn-1 Predicted to be involved in nuclear DNA replication. Predicted to be located in nucleus. Is an ortholog of human DONSON (DNA replication fork stabilization factor DONSON). WB:WBGene00016075 C24H12.6 Predicted to enable DNA binding activity. WB:WBGene00016076 C24H12.7 Enriched in NSM and pharynx based on microarray and tiling array studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including methylmercuric chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00016077 C24H12.8 Enriched in NSM and body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and tdc-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00016078 C24H12.9 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Alovudine; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00016080 C24H12.11 Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including mianserin; Alovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00016081 C25A6.1 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00016082 C25A8.1 Is affected by several genes including daf-12; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00016083 C25A8.2 Predicted to be located in membrane. WB:WBGene00016084 cht-3 Predicted to enable chitin binding activity and chitinase activity. Predicted to be involved in chitin catabolic process. Predicted to be located in extracellular region. Expressed in uterine toroidal epithelial cell and vulval cell. WB:WBGene00016085 C25A8.5 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00016087 C25A11.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00016088 clec-266 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Expressed in intestinal cell. WB:WBGene00016089 aexr-1 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00016090 aexr-2 Predicted to enable neuropeptide receptor activity. Involved in lysosome organization. Predicted to be located in membrane. WB:WBGene00016091 nhr-30 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head. WB:WBGene00016092 cyp-33B1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C8 (cytochrome P450 family 2 subfamily C member 8); and CYP2J2 (cytochrome P450 family 2 subfamily J member 2). WB:WBGene00016093 srsx-34 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00016094 C25E10.4 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00016095 C25E10.5 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00016096 C25E10.7 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00016097 C25E10.8 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. Expressed in intestine. WB:WBGene00016099 C25E10.10 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00016100 C25E10.11 Predicted to be located in membrane. WB:WBGene00016101 C25E10.12 Predicted to enable hydrolase activity. Is an ortholog of human MPPED1 (metallophosphoesterase domain containing 1) and MPPED2 (metallophosphoesterase domain containing 2). WB:WBGene00016102 C25F6.1 Enriched in several structures, including ABplpppapa; ABprpppapa; head mesodermal cell; nerve ring neurons; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Zidovudine; silicon dioxide nanoparticle; and cadmium based on RNA-seq and microarray studies. WB:WBGene00016103 dpyd-1 Predicted to enable NADP binding activity; dihydropyrimidine dehydrogenase (NADP+) activity; and uracil binding activity. Predicted to be involved in thymidine catabolic process; thymine catabolic process; and uracil catabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including acute lymphoblastic leukemia; dihydropyrimidine dehydrogenase deficiency; and gallbladder cancer. Is an ortholog of human DPYD (dihydropyrimidine dehydrogenase). WB:WBGene00016104 ddr-1 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Involved in motor neuron axon guidance and positive regulation of axon regeneration. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Expressed in hypodermis; intestinal muscle; nervous system; and pharynx. WB:WBGene00016105 C25F6.6 Enriched in MSaapaapa; MSpapaapa; g1P; and nerve ring neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by seven chemicals including D-glucose; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016106 itm-2 Predicted to enable amyloid-beta binding activity. Predicted to be involved in negative regulation of amyloid precursor protein biosynthetic process. Predicted to be located in Golgi apparatus and plasma membrane. Human ortholog(s) of this gene implicated in ITM2B-related cerebral amyloid angiopathy 1 and ITM2B-related cerebral amyloid angiopathy 2. Is an ortholog of human ITM2B (integral membrane protein 2B). WB:WBGene00016107 C25G6.1 Enriched in ABplaapappp; ABpraapappp; AIY; neurons; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; isp-1; and alg-1 based on microarray and RNA-seq studies. Is affected by Oligosaccharides and adsorbable organic bromine compound based on microarray studies. WB:WBGene00016108 C25G6.3 Predicted to enable CoA-ligase activity. WB:WBGene00016109 C25G6.4 Enriched in g2; intestine; neurons; and ventral nerve cord based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; clk-1; and sod-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including mianserin; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00016110 npr-11 Predicted to enable neuropeptide Y receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. Expressed in neurons and tail neurons. WB:WBGene00016111 C25H3.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00016112 C25H3.3 Predicted to enable acyl-CoA hydrolase activity. Is an ortholog of human ACOT13 (acyl-CoA thioesterase 13). WB:WBGene00016113 eif-2D Predicted to enable translation initiation factor activity. Predicted to be involved in formation of translation preinitiation complex. Is an ortholog of human EIF2D (eukaryotic translation initiation factor 2D). WB:WBGene00016114 flp-27 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. WB:WBGene00016115 mdt-26 Predicted to be located in nucleus. Is an ortholog of human TCEANC2 (transcription elongation factor A N-terminal and central domain containing 2). WB:WBGene00016116 C25H3.7 Predicted to be located in cytoplasm. WB:WBGene00016118 ndub-5 Predicted to be located in membrane and mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Expressed in hypodermis; intestine; and pharynx. Is an ortholog of human NDUFB5 (NADH:ubiquinone oxidoreductase subunit B5). WB:WBGene00016119 C25H3.10 Enriched in several structures, including coelomocyte; germ line; hypodermis; neurons; and ventral nerve cord based on tiling array; proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including Heme; D-glucose; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00016120 C25H3.11 Predicted to enable glycosyltransferase activity and metal ion binding activity. Predicted to be involved in mitochondrion organization; protein retention in Golgi apparatus; and protein targeting to vacuole. Predicted to be extrinsic component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 4. Is an ortholog of human VPS13D (vacuolar protein sorting 13 homolog D). WB:WBGene00016121 ift-43 Predicted to be located in cilium. Expressed in ciliated neurons. WB:WBGene00016123 C25H3.14 Predicted to enable acyl-CoA hydrolase activity. Is an ortholog of human ACOT13 (acyl-CoA thioesterase 13). WB:WBGene00016124 dnc-4 Part of dynactin complex. Is an ortholog of human DCTN4 (dynactin subunit 4). WB:WBGene00016125 C26B2.2 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00016126 nhr-258 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in hormone-mediated signaling pathway; regulation of transcription by RNA polymerase II; and tissue development. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Expressed in neurons. WB:WBGene00016128 elpc-4 Predicted to enable phosphorylase kinase regulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II and tRNA wobble uridine modification. Predicted to be located in cytoplasm. Predicted to be part of elongator holoenzyme complex and transcription elongation factor complex. Human ortholog(s) of this gene implicated in aniridia. Is an ortholog of human ELP4 (elongator acetyltransferase complex subunit 4). WB:WBGene00016129 C26B2.7 Predicted to be located in membrane. WB:WBGene00016130 C26B2.8 Enriched in GABAergic neurons; GLR; intestine; pharyngeal-intestinal valve; and pm6 based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; D-glucose; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Lustrin, cysteine-rich repeated domain; PEBP-like superfamily; and Lustrin, cysteine-rich repeated. WB:WBGene00016131 C26B9.1 Predicted to be located in membrane. Is an ortholog of human TMEM268 (transmembrane protein 268). WB:WBGene00016132 C26B9.2 Enriched in several structures, including CEP socket cell; muscle cell; neurons; retrovesicular ganglion; and tail hypodermis based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and let-60 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and stavudine based on RNA-seq and microarray studies. WB:WBGene00016133 C26B9.3 Enriched in several structures, including ABarpaapap; germ line; hypodermis; interfacial epithelial cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-four chemicals including Ethanol; methylmercury hydroxide; and D-glucose based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: GM2-AP, lipid-recognition domain superfamily. WB:WBGene00016134 C26B9.5 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. WB:WBGene00016135 C26B9.6 Predicted to enable poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human RNF146 (ring finger protein 146). WB:WBGene00016136 C26B9.7 Enriched in germline precursor cell; hypodermis; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including tryptophan; methylmercury hydroxide; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00016137 C26E6.1 Predicted to enable histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. WB:WBGene00016138 flh-2 Enables sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription and nematode larval development. Located in nucleus. Expressed in hypodermis and vulva. WB:WBGene00016139 ntl-9 Involved in hemidesmosome assembly. Predicted to be located in P-body. Predicted to be part of CCR4-NOT core complex. Expressed in gonad. Is an ortholog of human CNOT9 (CCR4-NOT transcription complex subunit 9). WB:WBGene00016140 rpb-2 Predicted to enable several functions, including DNA-directed 5'-3' RNA polymerase activity; metal ion binding activity; and ribonucleoside binding activity. Predicted to contribute to RNA polymerase II activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II, core complex. Expressed in head and tail. Is an ortholog of human POLR2B (RNA polymerase II subunit B). WB:WBGene00016142 mrps-18C Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 9. Is an ortholog of human MRPL3 (mitochondrial ribosomal protein L3). WB:WBGene00016143 eri-9 Enriched in germ line; germline precursor cell; intestine; and neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including hsf-1; gld-1; and sir-2.1 based on proteomic; microarray; and RNA-seq studies. Is affected by ten chemicals including D-glucose; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zc3h12a-like Ribonuclease NYN domain. WB:WBGene00016144 mmab-1 Predicted to enable corrinoid adenosyltransferase activity. Used to study methylmalonic acidemia. Human ortholog(s) of this gene implicated in methylmalonic acidemia cblB type. Is an ortholog of human MMAB (metabolism of cobalamin associated B). WB:WBGene00016145 C26E6.12 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in mitochondrion. Is an ortholog of human GTPBP10 (GTP binding protein 10). WB:WBGene00016146 C26F1.1 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; rotenone; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00016147 cyp-32A1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Is an ortholog of human CYP4V2 (cytochrome P450 family 4 subfamily V member 2). WB:WBGene00016148 C26F1.3 Enriched in several structures, including AFD; M cell; body wall muscle cell; germ line; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eight chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016149 frpr-3 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in head neurons and nerve ring. WB:WBGene00016150 hint-3 Predicted to be located in membrane. Is an ortholog of human HINT3 (histidine triad nucleotide binding protein 3). WB:WBGene00016151 smc-5 Predicted to enable single-stranded DNA binding activity. Involved in meiotic DNA double-strand break processing involved in reciprocal meiotic recombination. Located in condensed nuclear chromosome. Expressed in germ line. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome. Is an ortholog of human SMC5 (structural maintenance of chromosomes 5). WB:WBGene00016152 pho-12 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00016153 idpb-2 Enriched in FLPL; FLPR; URXL; URXR; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including D-glucose; Zidovudine; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00016154 szy-5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within with a positive effect on microtubule cytoskeleton organization. Predicted to be located in nucleus. WB:WBGene00016155 C27A12.4 Enriched in NSM; Z1.p; Z4.a; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00016156 ari-1.3 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1). WB:WBGene00016157 ari-1.2 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1). WB:WBGene00016158 ari-1.1 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and ubiquitin-dependent protein catabolic process. Located in cytoplasm and nucleus. Expressed in several structures, including germ line; hermaphrodite distal tip cell; neurons; non-striated muscle; and somatic nervous system. Is an ortholog of human ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1). WB:WBGene00016159 pigo-1 Predicted to enable mannose-ethanolamine phosphotransferase activity. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 2. Is an ortholog of human PIGO (phosphatidylinositol glycan anchor biosynthesis class O). WB:WBGene00016160 C27D6.1 Enriched in head neurons; hypodermis; rectal epithelial cell; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and sir-2.1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by Progesterone; Acrylamide; and Colistin based on microarray studies. Human CCDC170 enables microtubule binding activity. Is predicted to encode a protein with the following domain: Coiled-coil domain-containing protein 170-like. Is an ortholog of human CCDC170 (coiled-coil domain containing 170). WB:WBGene00016161 C27D6.3 Predicted to be located in membrane. WB:WBGene00016162 crh-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cAMP response element binding activity. Involved in defense response to Gram-negative bacterium; positive regulation of dauer entry; and regulation of gene expression. Predicted to be located in nucleus. Expressed in body wall musculature; seam cell; spermatheca; and tail. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 16; prostate adenocarcinoma; and prostate carcinoma in situ. Is an ortholog of human CREB3L1 (cAMP responsive element binding protein 3 like 1) and CREB3L2 (cAMP responsive element binding protein 3 like 2). WB:WBGene00016163 C27D9.1 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. WB:WBGene00016164 C27D9.2 Predicted to be located in cell surface and extracellular region. WB:WBGene00016165 wdr-60 Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in intraciliary transport. Predicted to be located in ciliary plasm. Predicted to be part of cytoplasmic dynein complex. Used to study short-rib thoracic dysplasia 8 with or without polydactyly. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 8 with or without polydactyly. Is an ortholog of human DYNC2I1 (dynein 2 intermediate chain 1). WB:WBGene00016166 C27F2.4 Predicted to enable rRNA (guanine) methyltransferase activity. Predicted to be involved in rRNA (guanine-N7)-methylation. Predicted to be located in nucleolus. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Is an ortholog of human BUD23 (BUD23 rRNA methyltransferase and ribosome maturation factor). WB:WBGene00016167 vps-22 Predicted to be involved in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be part of ESCRT II complex. Expressed in body wall musculature; pharyngeal muscle cell; pharynx; and vulval muscle. Is an ortholog of human SNF8 (SNF8 subunit of ESCRT-II). WB:WBGene00016168 C27F2.6 Predicted to enable potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00016169 C27F2.7 Expressed in head neurons; hypodermis; intestine; and tail neurons. Is predicted to encode a protein with the following domains: F-box-like; F-box-like domain superfamily; and F-box domain. WB:WBGene00016170 tmem-131 Located in endoplasmic reticulum membrane. Expressed in hypodermis; intestine; and neurons. Is an ortholog of human TMEM131 (transmembrane protein 131). WB:WBGene00016171 C27F2.10 Predicted to enable RNA binding activity and double-stranded DNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus; post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery; and transcription elongation by RNA polymerase II. Predicted to be part of transcription export complex 2. Is an ortholog of human PCID2 (PCI domain containing 2). WB:WBGene00016172 C27H5.2 Predicted to enable DNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nucleus. WB:WBGene00016173 fust-1 Predicted to enable RNA binding activity and transcription coregulator activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in gonad; head; intestinal cell; neurons; and tail. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 6; connective tissue cancer (multiple); and essential tremor 4. Is an ortholog of human FUS (FUS RNA binding protein). WB:WBGene00016174 mfsd-13.2 Predicted to be located in membrane. Is an ortholog of human MFSD13A (major facilitator superfamily domain containing 13A). WB:WBGene00016175 C27H5.6 Predicted to be located in membrane. WB:WBGene00016177 C28C12.1 Predicted to be located in membrane. WB:WBGene00016178 mesp-1 Expressed in germ line. WB:WBGene00016179 srlf-2 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00016180 srlf-3 Expressed in pharyngeal muscle cell and tail neurons. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00016181 C28C12.11 Predicted to be located in membrane. WB:WBGene00016182 C28C12.12 Enriched in germ line; germline precursor cell; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including manganese chloride; D-glucose; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00016183 C28F5.1 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; tryptophan; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00016184 glb-9 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in neurons and somatic nervous system. WB:WBGene00016185 C28F5.4 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and npr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including antimycin; Doxycycline; and paraquat based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in Alzheimer's disease; diabetic encephalopathy; and type 2 diabetes mellitus. Human IDE enables several functions, including insulin binding activity; ion binding activity; and protein homodimerization activity. Is an ortholog of human IDE (insulin degrading enzyme). WB:WBGene00016186 C28F5.5 No description available WB:WBGene00016187 C28G1.2 Predicted to be located in extracellular space. WB:WBGene00016188 sec-15 Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to be part of exocyst. Expressed in embryonic cell; excretory canal; and hypodermis. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia with joint laxity type 3. Is an ortholog of human EXOC6B (exocyst complex component 6B). WB:WBGene00016189 sprp-4 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Expressed in dorsal nerve cord; nerve ring; and ventral nerve cord. WB:WBGene00016190 rcs-1 Predicted to enable zinc ion binding activity. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; Sweet syndrome; and hematologic cancer (multiple). Is an ortholog of several human genes including MEFV (MEFV innate immunity regulator, pyrin); TRIM21 (tripartite motif containing 21); and TRIM27 (tripartite motif containing 27). WB:WBGene00016191 C28G1.6 Predicted to enable zinc ion binding activity. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; Sweet syndrome; and hematologic cancer (multiple). Is an ortholog of several human genes including MEFV (MEFV innate immunity regulator, pyrin); TRIM21 (tripartite motif containing 21); and TRIM27 (tripartite motif containing 27). WB:WBGene00016192 bcl-7 Predicted to be involved in Wnt signaling pathway; apoptotic process; and cell differentiation. Predicted to be located in nucleus. Expressed in distal tip cell; germ cell; and gonadal sheath cell. Is an ortholog of human BCL7A (BAF chromatin remodeling complex subunit BCL7A). WB:WBGene00016193 C28H8.2 Enriched in AFD; PLM; and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-2; rrf-3; and elt-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Family of unknown function (DUF5390) and Protein of unknown function DUF5390. WB:WBGene00016194 C28H8.3 Predicted to enable several functions, including ATP binding activity; helicase activity; and nucleic acid binding activity. Predicted to be located in cytoplasm. Is an ortholog of human DDX60 (DExD/H-box helicase 60) and DDX60L (DExD/H-box 60 like). WB:WBGene00016195 erd-2.2 Predicted to enable ER retention sequence binding activity. Predicted to be involved in protein retention in ER lumen; protein transport; and vesicle-mediated transport. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 21. Is an ortholog of human KDELR2 (KDEL endoplasmic reticulum protein retention receptor 2). WB:WBGene00016196 C28H8.5 Enriched in AFD; hypodermis; and touch receptor neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Ethanol; 1-methylnicotinamide; and Tunicamycin based on RNA-seq and microarray studies. Human THAP4 enables several functions, including heme binding activity; identical protein binding activity; and peroxynitrite isomerase activity. Is predicted to encode a protein with the following domains: ShKT domain; Nitrobindin family; ShK domain-like; THAP4-like, heme-binding beta-barrel domain; and Calycin. Is an ortholog of human THAP4 (THAP domain containing 4). WB:WBGene00016197 pxl-1 Enables vinculin binding activity. Involved in muscle structure development; nematode larval development; and pharyngeal pumping. Located in adherens junction; contractile fiber; and podosome. Expressed in pharyngeal muscle cell and pharynx. Is an ortholog of human LPXN (leupaxin) and PXN (paxillin). WB:WBGene00016198 C28H8.7 Enriched in neurons; pharyngeal-intestinal valve; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including lin-4; lin-14; and clk-1 based on microarray and RNA-seq studies. Is affected by Alovudine; resveratrol; and Atrazine based on RNA-seq and microarray studies. WB:WBGene00016199 C28H8.8 Enriched in MSaapapa; MSpapapa; and tail hypodermis based on single-cell RNA-seq studies. Is affected by several genes including let-60; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Methyltransferase FkbM domain and Methyltransferase FkbM. WB:WBGene00016200 dpff-1 Predicted to enable metal ion binding activity. Involved in apoptotic process; meiotic cell cycle; and response to heat. Located in nucleus. Expressed widely. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 7. Is an ortholog of human DPF2 (double PHD fingers 2) and DPF3 (double PHD fingers 3). WB:WBGene00016201 tdo-2 Predicted to enable heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in tryptophan catabolic process to acetyl-CoA. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Is an ortholog of human TDO2 (tryptophan 2,3-dioxygenase). WB:WBGene00016202 kle-2 Predicted to enable chromatin binding activity. Involved in mitotic sister chromatid segregation. Predicted to be located in nucleus. Predicted to be part of condensin complex. Is an ortholog of human NCAPH2 (non-SMC condensin II complex subunit H2). WB:WBGene00016203 tag-250 Predicted to be involved in P granule organization; piRNA processing; and spermatogenesis. Predicted to be located in P granule. Expressed in hypodermis; intestine; neurons; and pharyngeal muscle cell. Is an ortholog of human TDRD15 (tudor domain containing 15). WB:WBGene00016204 gsto-1 Enables glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Involved in cellular response to extracellular stimulus; obsolete oxidation-reduction process; and response to superoxide. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Is an ortholog of human GSTO1 (glutathione S-transferase omega 1) and GSTO2 (glutathione S-transferase omega 2). WB:WBGene00016206 C29E4.9 Enriched in CEPshDL; CEPshDR; CEPshVL; CEPshVR; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and sir-2.1 based on RNA-seq and microarray studies. Is affected by four chemicals including Zidovudine; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00016207 C29E4.10 Predicted to enable galactosylceramidase activity. Predicted to be involved in galactosylceramide catabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in Creutzfeldt-Jakob disease; Krabbe disease; and Mycoplasma pneumoniae pneumonia. Is an ortholog of human GALC (galactosylceramidase). WB:WBGene00016208 C29E4.11 Is affected by several genes including let-60; sir-2.1; and isp-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Quercetin; Hydrolyzable Tannins; and Humic Substances based on microarray studies. WB:WBGene00016209 C29E4.12 Predicted to be located in mitochondrion. Is an ortholog of human FMC1 (formation of mitochondrial complex V assembly factor 1 homolog) and FMC1-LUC7L2 (FMC1-LUC7L2 readthrough). WB:WBGene00016210 C29F5.1 Located in sarcoplasmic reticulum. Expressed in anal depressor muscle; anal sphincter muscle; body wall musculature; and vulval muscle. WB:WBGene00016211 sdz-3 Enriched in body wall muscle cell; germ line; muscle cell; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Rifampin; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00016212 nyn-3 Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleus. Expressed in gonad. WB:WBGene00016213 C29F5.5 Is affected by several genes including eat-2; sir-2.1; and drh-3 based on microarray and RNA-seq studies. Is affected by resveratrol; dafa#1; and Sirolimus based on microarray studies. WB:WBGene00016214 C29F5.6 No description available WB:WBGene00016215 glb-10 Predicted to enable heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Located in plasma membrane. Expressed in several structures, including excretory cell; gonad; neurons; non-striated muscle; and somatic nervous system. WB:WBGene00016216 pals-22 Expressed widely. WB:WBGene00016217 C29F9.2 Enriched in ASER; arcade cell; intestine; and male-specific anatomical entity based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by nineteen chemicals including hydrogen sulfide; methylmercury hydroxide; and procyanidin based on microarray and RNA-seq studies. WB:WBGene00016218 pals-23 Involved in innate immune response. WB:WBGene00016219 pals-24 Enriched in GABAergic neurons; head mesodermal cell; intestine; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; manganese chloride; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00016220 C29F9.5 Predicted to enable histone acetyltransferase activity; metal ion binding activity; and transcription coregulator activity. Predicted to be involved in DNA-templated transcription; chromatin remodeling; and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016221 C29F9.6 Predicted to enable histone acetyltransferase activity; metal ion binding activity; and transcription coregulator activity. Predicted to be involved in DNA-templated transcription; chromatin remodeling; and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016222 C29F9.8 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00016223 C29F9.9 Is affected by several genes including daf-12; lin-15B; and mut-2 based on microarray and tiling array studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00016224 fbxa-57 Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00016225 fbxa-58 Enriched in AVA and intestine based on tiling array and microarray studies. Is affected by several genes including daf-16; eat-2; and lin-35 based on microarray and RNA-seq studies. Is affected by paraquat; allantoin; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. WB:WBGene00016226 C29F9.12 Enriched in ABalaapppa; ABalapaapa; ABplpaaaap; ABprpaaaap; and rectal epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including glp-1; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including cadmium; Progesterone; and Colistin based on RNA-seq and microarray studies. WB:WBGene00016227 nhr-280 Predicted to be located in nucleus. WB:WBGene00016230 C29G2.2 Expressed in head. WB:WBGene00016231 C29G2.3 Enriched in hypodermis and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and stavudine based on microarray and RNA-seq studies. WB:WBGene00016232 srt-4 Predicted to be located in membrane. WB:WBGene00016233 nhr-290 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016234 C29G2.6 Predicted to be located in membrane. WB:WBGene00016235 C29H12.2 Predicted to be located in intracellular membrane-bounded organelle and membrane. Is an ortholog of human SLC35F6 (solute carrier family 35 member F6). WB:WBGene00016236 heri-1 Predicted to enable protein serine/threonine kinase activity. Predicted to be located in cytoplasm. Expressed in several structures, including Psub3; Psub4; Z2; Z3; and germ cell. WB:WBGene00016237 C29H12.6 Expressed in marginal cell. WB:WBGene00016238 mob-4 Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm. Expressed in several structures, including hypodermal cell and vulval cell. Is an ortholog of human MOB4 (MOB family member 4, phocein). WB:WBGene00016239 C30A5.4 Enriched in several structures, including ABalpapppa; ABaraapapaa; germ line; neurons; and pharyngeal cell based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; multi-walled carbon nanotube; and iron oxide nanoparticle based on microarray and RNA-seq studies. WB:WBGene00016241 C30A5.9 No description available WB:WBGene00016242 C30A5.10 Predicted to enable group II metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to be located in membrane. WB:WBGene00016244 C30B5.2 Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway. Predicted to be located in endosome. Is an ortholog of human LEPROT (leptin receptor overlapping transcript) and LEPROTL1 (leptin receptor overlapping transcript like 1). WB:WBGene00016245 rbmx-2 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U2 snRNP and precatalytic spliceosome. Is an ortholog of human RBMX2 (RNA binding motif protein X-linked 2). WB:WBGene00016246 daf-37 Enables ascr#2 binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in G protein-coupled receptor signaling pathway involved in dauer larval development and G protein-coupled receptor signaling pathway involved in social behavior. Located in non-motile cilium. Expressed in head neurons. WB:WBGene00016247 C30B5.6 Enriched in GABAergic neurons; SDQ; coelomocyte; excretory cell; and neurons based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including methylmercury hydroxide; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00016248 srsy-2 Predicted to be located in membrane. WB:WBGene00016249 mrpl-32 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL32 (mitochondrial ribosomal protein L32). WB:WBGene00016250 hsp-110 Predicted to enable adenyl-nucleotide exchange factor activity. Involved in determination of adult lifespan; protein folding; and response to topologically incorrect protein. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; autoimmune disease (multiple); and type 2 diabetes mellitus. Is an ortholog of human HSPA4 (heat shock protein family A (Hsp70) member 4) and HSPH1 (heat shock protein family H (Hsp110) member 1). WB:WBGene00016253 C30E1.4 Predicted to enable RNA transmembrane transporter activity and double-stranded RNA binding activity. Predicted to be involved in RNA transport. Predicted to be located in lysosome and plasma membrane. WB:WBGene00016254 fbxb-114 Enriched in neurons and pharynx based on microarray; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Tunicamycin; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00016255 C30E1.6 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00016257 C30E1.8 Enriched in neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including npr-1; hpl-2; and smn-1 based on tiling array and RNA-seq studies. Is affected by Cry5B and Sirolimus based on microarray studies. WB:WBGene00016258 vha-16 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in vacuolar acidification and vacuolar transport. Predicted to be located in early endosome. Predicted to be part of plasma membrane proton-transporting V-type ATPase complex and vacuolar proton-transporting V-type ATPase complex. Expressed in head and tail. Is an ortholog of human ATP6V0D1 (ATPase H+ transporting V0 subunit d1). WB:WBGene00016259 C30F8.3 Enriched in BDU; rectal epithelial cell; rectum; sensory neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including Ethanol; methylmercuric chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00016260 rege-1 Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleus. Expressed in tail. Human ortholog(s) of this gene implicated in hepatitis B. Is an ortholog of human ZC3H12A (zinc finger CCCH-type containing 12A); ZC3H12B (zinc finger CCCH-type containing 12B); and ZC3H12C (zinc finger CCCH-type containing 12C). WB:WBGene00016261 C30F12.2 Predicted to enable ATP hydrolysis activity. Predicted to be located in mitochondrion. Expressed in head. Is an ortholog of human AFG1L (AFG1 like ATPase). WB:WBGene00016262 C30F12.3 Predicted to be located in lysosomal membrane. WB:WBGene00016263 C30F12.4 Enriched in several structures, including G2; cholinergic neurons; germ line; muscle cell; and rect_D based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00016264 C30F12.5 Predicted to be located in membrane. WB:WBGene00016265 trhr-1 Predicted to enable thyrotropin-releasing hormone receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in pm4 and pm5. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 7 and hypertension. Is an ortholog of human TRHR (thyrotropin releasing hormone receptor). WB:WBGene00016266 idhg-2 Predicted to enable NAD binding activity and magnesium ion binding activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to be located in mitochondrion. Is an ortholog of human IDH3G (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma). WB:WBGene00016267 C30G4.1 No description available WB:WBGene00016268 C30G4.2 Enriched in I5 neuron; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and met-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00016269 C30G4.4 Predicted to be involved in regulation of transcription by RNA polymerase II. WB:WBGene00016271 irld-23 Enriched in ALNL; ALNR; body wall musculature; and neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00016273 C30G12.1 Enriched in GABAergic neurons and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; RNA-seq; and tiling array studies. Is affected by eight chemicals including multi-walled carbon nanotube; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Pepsin inhibitor-3 domain superfamily. WB:WBGene00016274 C30G12.2 Predicted to enable oxidoreductase activity. Predicted to be located in cytoplasm. WB:WBGene00016276 C30G12.4 Enriched in IL socket cell; arc ant V; hypodermis; intestine; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercury hydroxide; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00016277 C30G12.6 Enriched in several structures, including ABplpapapa; ABplpppapa; RID; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; age-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including manganese chloride; D-glucose; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Armadillo-type fold. WB:WBGene00016278 erp-44.1 Predicted to enable protein disulfide isomerase activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment. Is an ortholog of human ERP44 (endoplasmic reticulum protein 44). WB:WBGene00016279 C31B8.1 Predicted to be located in membrane. WB:WBGene00016280 C31B8.2 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including mut-2; mir-34; and adr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00016281 pals-32 Enriched in several structures, including coelomocyte; dopaminergic neurons; excretory cell; rectal epithelial cell; and ventral nerve cord based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including tryptophan; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00016282 C31B8.7 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00016283 zmp-3 Enables metallopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to be located in extracellular space. Expressed in anchor cell. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and reproductive organ cancer (multiple). Is an ortholog of several human genes including MMP1 (matrix metallopeptidase 1); MMP3 (matrix metallopeptidase 3); and MMP8 (matrix metallopeptidase 8). WB:WBGene00016284 C31B8.9 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00016285 C31B8.12 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00016286 C31H1.1 Enriched in several structures, including AVK; anal sphincter muscle; germ line; head neurons; and sensory neurons based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00016287 C31H1.2 Predicted to be located in membrane. WB:WBGene00016288 C31H1.5 Predicted to enable calcium ion binding activity and phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion; lipid catabolic process; and phospholipid metabolic process. Predicted to be located in extracellular region. Is an ortholog of human PLA2G12A (phospholipase A2 group XIIA) and PLA2G12B (phospholipase A2 group XIIB). WB:WBGene00016289 lntl-1 Enriched in several structures, including anterior ganglion; arcade cell; excretory system; muscle cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00016291 oops-1 Enriched in AVE; SIB; germ line; and germline precursor cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including manganese chloride; bisphenol S; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00016292 tbc-7 Predicted to be located in cytoplasmic vesicle; membrane; and synapse. Expressed in head and intestine. Human ortholog(s) of this gene implicated in DOORS syndrome; epilepsy (multiple); and nonsyndromic deafness (multiple). Is an ortholog of human TBC1D24 (TBC1 domain family member 24). WB:WBGene00016293 C31H2.3 Enriched in intestine; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00016294 C31H2.4 Predicted to enable 4-hydroxyphenylpyruvate dioxygenase activity. Predicted to be involved in tyrosine catabolic process. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. WB:WBGene00016295 fbxc-40 Enriched in several structures, including ABalaaaarl; accessory cell; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016296 fbxc-16 Is affected by several genes including daf-16; daf-2; and mex-3 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00016297 fbxc-15 Enriched in several structures, including ABalpppppa; ABalppppppa; ABalppppppp; AUA; and amphid neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and set-2 based on microarray and RNA-seq studies. Is affected by four chemicals including 1-methylnicotinamide; methylmercuric chloride; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016298 fbxc-14 Enriched in amphid neurons and excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; mianserin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016299 C32B5.6 Enriched in several structures, including RME; accessory cell; arc ant V; germ line; and rect_D based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00016300 C32B5.7 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; cerebrovascular disease (multiple); and pycnodysostosis. Is an ortholog of human CTSK (cathepsin K) and CTSS (cathepsin S). WB:WBGene00016301 fbxc-6 Enriched in intestine; sensory neurons; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including eat-2; sir-2.1; and sek-1 based on microarray and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00016302 fbxc-7 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016303 fbxc-32 Enriched in ABplapppapp; ABprapppapp; g2; germ line; and neurons based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016304 fbxc-41 Enriched in NSM; neurons; sensory neurons; and ventral nerve cord based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00016305 fbxc-57 Enriched in AVE; NSM; sensory neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including sir-2.1; sek-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016306 C32B5.13 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. WB:WBGene00016307 fbxc-18 Enriched in several structures, including ABalaapppp; ABalapaapp; ABalppappa; ABarappppa; and ciliated neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; methylmercuric chloride; and mianserin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016308 C32B5.15 Enriched in several structures, including ABplaapaaa; ABpraapaaa; MSpaaaaa; NSM; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; mianserin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00016309 sdz-4 Expressed in several structures, including Caa; Cap; Cpa; Ea; and Psub4. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016310 txt-18 Enriched in anterior hypodermis; arcade cell; head mesodermal cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00016311 efr-3 Predicted to be involved in protein localization to plasma membrane. Predicted to be located in plasma membrane. Is an ortholog of human EFR3B (EFR3 homolog B). WB:WBGene00016312 C32D5.4 Enriched in AVA; M cell; enteric muscle; germ line; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by seventeen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00016313 set-4 Predicted to enable histone H4K20me methyltransferase activity. Involved in determination of adult lifespan. Predicted to be located in chromosome and nucleus. Expressed in several structures, including hypodermis and muscle cell. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 51. Is an ortholog of human KMT5B (lysine methyltransferase 5B) and KMT5C (lysine methyltransferase 5C). WB:WBGene00016314 ttc-39B Enriched in arc ant V; excretory cell; head ganglion; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Heme; D-glucose; and levamisole based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Tetratricopeptide-like helical domain superfamily; Iml2/Tetratricopeptide repeat protein 39; Tetratricopeptide repeat; and Inclusion body clearance protein Iml2/Tetratricopeptide repeat protein 39. Is an ortholog of human TTC39A (tetratricopeptide repeat domain 39A) and TTC39B (tetratricopeptide repeat domain 39B). WB:WBGene00016315 C32D5.7 Enriched in arcade cell; intestine; neurons; and pharyngeal muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00016316 C32D5.8 Enriched in several structures, including ABplapaaaap; ABprapaaaap; dopaminergic neurons; germ line; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; proteomic; and RNA-seq studies. Is affected by fourteen chemicals including aldicarb; rotenone; and allantoin based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Thioredoxin-like superfamily; and Thioredoxin-like. Is an ortholog of human NXNL2 (nucleoredoxin like 2). WB:WBGene00016317 C32D5.10 Predicted to enable ubiquitin-protein transferase activity. WB:WBGene00016318 C32D5.11 Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 6A. Is an ortholog of human PEX10 (peroxisomal biogenesis factor 10). WB:WBGene00016319 C32D5.12 Predicted to enable dTDP-glucose 4,6-dehydratase activity. Predicted to be involved in steroid biosynthetic process. WB:WBGene00016320 C32E8.1 Predicted to enable metal ion binding activity. WB:WBGene00016321 tppp-1 Predicted to enable tubulin binding activity. Predicted to be involved in microtubule bundle formation; microtubule polymerization; and positive regulation of protein polymerization. Predicted to be located in microtubule. Is an ortholog of human TPPP (tubulin polymerization promoting protein); TPPP2 (tubulin polymerization promoting protein family member 2); and TPPP3 (tubulin polymerization promoting protein family member 3). WB:WBGene00016322 C32E8.4 Enriched in several structures, including MC neuron; RID; amphid sheath cell; germ line; and sperm based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00016323 pmlr-1 Predicted to enable mRNA binding activity. Predicted to be involved in miRNA processing. Predicted to be located in nucleus. Is an ortholog of human SNIP1 (Smad nuclear interacting protein 1). WB:WBGene00016324 acs-24 Predicted to enable CoA-ligase activity. WB:WBGene00016325 C32E8.9 Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in cytosol. Is an ortholog of human ECHDC1 (ethylmalonyl-CoA decarboxylase 1). WB:WBGene00016326 ubr-1 Enables ubiquitin conjugating enzyme binding activity. Involved in negative regulation of glutamate metabolic process and regulation of backward locomotion. Predicted to be located in cytoplasm. Predicted to be part of ubiquitin ligase complex. Expressed in body wall musculature; lateral ganglion; pharynx; and seam cell. Human ortholog(s) of this gene implicated in Johanson-Blizzard syndrome and atherosclerosis. Is an ortholog of human UBR1 (ubiquitin protein ligase E3 component n-recognin 1) and UBR2 (ubiquitin protein ligase E3 component n-recognin 2). WB:WBGene00016327 C32E12.1 Enriched in AFD; arc ant V; germ line; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; nicotinic acid; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00016328 pde-5 Predicted to enable 3',5'-cyclic-GMP phosphodiesterase activity and cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Involved in several processes, including determination of adult lifespan; negative regulation of cGMP-mediated signaling; and response to alkaline pH. Expressed in AFDL and AFDR. Is an ortholog of human PDE10A (phosphodiesterase 10A). WB:WBGene00016329 osr-1 Enriched in ABalpapaap; ABarappaap; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq and microarray studies. WB:WBGene00016330 C32E12.4 Predicted to enable hydrolase activity. WB:WBGene00016331 obr-4 Enables calmodulin binding activity. Predicted to be involved in sterol transport. Predicted to be located in cytosol; intracellular membrane-bounded organelle; and membrane. Expressed in tail. Is an ortholog of human OSBPL9 (oxysterol binding protein like 9). WB:WBGene00016332 C32F10.4 Predicted to be located in membrane. WB:WBGene00016333 C32F10.8 Predicted to enable L-alanine:2-oxoglutarate aminotransferase activity. Predicted to be involved in L-alanine catabolic process and biosynthetic process. Expressed in mc1 and pm3. Human ortholog(s) of this gene implicated in liver cancer; liver cirrhosis; and non-alcoholic fatty liver disease. Is an ortholog of human GPT (glutamic--pyruvic transaminase) and GPT2 (glutamic--pyruvic transaminase 2). WB:WBGene00016334 C33C12.1 Enriched in AVE and neurons based on tiling array studies. Is affected by several genes including daf-2; daf-18; and unc-70 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00016335 gba-1 Predicted to enable glucosylceramidase activity. Predicted to be involved in glucosylceramide catabolic process. WB:WBGene00016336 C33C12.4 Predicted to be located in membrane. WB:WBGene00016337 fbxb-38 Enriched in MSpaapaa; SIBDL; SIBDR; SIBVL; and SIBVR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00016338 srb-14 Is affected by several genes including clk-1; pgl-1; and sod-2 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00016339 C33C12.7 Enriched in coelomocyte; germ line; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00016340 gba-2 Predicted to enable glucosylceramidase activity. Predicted to be involved in glucosylceramide catabolic process. WB:WBGene00016341 mtq-2 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity and protein methyltransferase activity. Predicted to be involved in macromolecule methylation; nitrogen compound metabolic process; and primary metabolic process. Predicted to be part of eRF1 methyltransferase complex. Is an ortholog of human N6AMT1 (N-6 adenine-specific DNA methyltransferase 1). WB:WBGene00016343 cnnm-3 Predicted to enable transmembrane transporter activity. Involved in several processes, including determination of adult lifespan; magnesium ion homeostasis; and positive regulation of developmental process. Located in basolateral plasma membrane. Expressed in hypodermis and rectum. Human ortholog(s) of this gene implicated in Jalili syndrome and renal hypomagnesemia 6. Is an ortholog of several human genes including CNNM1 (cyclin and CBS domain divalent metal cation transport mediator 1); CNNM3 (cyclin and CBS domain divalent metal cation transport mediator 3); and CNNM4 (cyclin and CBS domain divalent metal cation transport mediator 4). WB:WBGene00016344 rsef-1 Predicted to enable GTP binding activity; GTPase activity; and calcium ion binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in perinuclear region of cytoplasm. Expressed in g1; spermathecal-uterine junction; and uterus. Is an ortholog of human RASEF (RAS and EF-hand domain containing). WB:WBGene00016345 C33E10.1 Enriched in several structures, including ABalaapppa; ABalapaapa; AVK; amphid neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00016346 fbxa-120 Enriched in several structures, including ABalppppppp; ABplpppapa; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-10; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00016347 C33E10.5 Is affected by several genes including eat-2; pgl-1; and eri-1 based on RNA-seq and microarray studies. Is affected by five chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00016348 C33E10.6 No description available WB:WBGene00016349 C33E10.8 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; multi-walled carbon nanotube; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00016350 C33E10.10 Predicted to be located in membrane. Expressed in pharynx. Is an ortholog of human DHRS7B (dehydrogenase/reductase 7B) and DHRS7C (dehydrogenase/reductase 7C). WB:WBGene00016351 C33F10.1 Enriched in amphid sheath cell; body wall muscle cell; sperm; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray and RNA-seq studies. Is affected by thirty chemicals including Heme; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00016352 tbck-1 Predicted to enable GTPase activator activity. Predicted to be involved in phosphorylation. Is an ortholog of human TBCK (TBC1 domain containing kinase). WB:WBGene00016353 C33F10.4 Enriched in germ line; neurons; rect_D; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00016354 rig-6 Predicted to enable cell-cell adhesion mediator activity. Involved in several processes, including axon guidance; negative regulation of defecation rhythm; and regulation of locomotion. Located in axon; neuronal cell body; and synapse. Expressed in several structures, including body wall musculature; neurons; non-striated muscle; rectal epithelium; and spermatheca. Human ortholog(s) of this gene implicated in several diseases, including Compton-North congenital myopathy; familial adult myoclonic epilepsy 5; and high grade glioma. Is an ortholog of human CNTN6 (contactin 6). WB:WBGene00016355 lact-5 Enriched in several structures, including ABarpaapap; anterior hypodermis; lateral ganglion; rectal epithelium; and sensory neurons based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; 4-bromodiphenyl ether; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Beta-lactamase; Beta-lactamase/transpeptidase-like; and Beta-lactamase-related. WB:WBGene00016356 C33F10.8 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in motor neuron axon guidance. WB:WBGene00016357 C33F10.11 Predicted to be located in membrane. WB:WBGene00016358 C33F10.12 Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human SLC25A3 (solute carrier family 25 member 3). WB:WBGene00016359 fbxb-88 Enriched in several structures, including GLR; RIC; RID; amphid neurons; and pharyngeal neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00016360 C33G8.2 Enriched in AFD and excretory gland cell based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00016361 drd-10 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by twenty-five chemicals including Nitric Oxide; rotenone; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00016362 spig-10 Enriched in ALN; amphid sheath cell; intestine; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; D-glucose; and bisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00016363 srab-4 Predicted to be located in membrane. Expressed in neurons and pm6. WB:WBGene00016364 nhr-161 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016365 nhr-139 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016366 nhr-140 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016367 nhr-162 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016368 nhr-163 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016369 C33G8.13 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00016370 C33H5.1 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00016371 C33H5.2 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00016373 swd-2.1 Predicted to enable chromatin binding activity. Predicted to be involved in DNA-templated transcription termination. Predicted to be located in nucleus. Predicted to be part of Set1C/COMPASS complex. Is an ortholog of human WDR82 (WD repeat domain 82). WB:WBGene00016374 swd-2.2 Predicted to enable chromatin binding activity. Involved in programmed cell death. Predicted to be located in nucleus. Predicted to be part of Set1C/COMPASS complex. Expressed in linker cell. Is an ortholog of human WDR82 (WD repeat domain 82). WB:WBGene00016375 rpap-3 Enriched in germ line; head mesodermal cell; intestine; muscle cell; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; set-2; and ain-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Tetratricopeptide-like helical domain superfamily; RNA-polymerase II-associated protein 3-like, C-terminal domain; Tetratricopeptide repeat; and Potential Monad-binding region of RPAP3. WB:WBGene00016376 sec-10 Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to be located in cytoplasm. Predicted to be part of exocyst. Expressed in several structures, including coelomocyte; excretory canal; head neurons; intestine; and reproductive system. Is an ortholog of human EXOC5 (exocyst complex component 5). WB:WBGene00016378 imp-3 Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in membrane protein proteolysis and signal peptide processing. Predicted to be located in membrane. WB:WBGene00016379 C33H5.13 Involved in innate immune response. WB:WBGene00016380 ntp-1 Enables pyrophosphatase activity. Involved in ribonucleotide metabolic process. Located in Golgi apparatus and perinuclear region of cytoplasm. Is an ortholog of human ENTPD4 (ectonucleoside triphosphate diphosphohydrolase 4) and ENTPD7 (ectonucleoside triphosphate diphosphohydrolase 7). WB:WBGene00016381 sgo-1 Predicted to be involved in cell division; chromosome segregation; and organelle organization. Predicted to be located in chromosome, centromeric region and nucleus. WB:WBGene00016382 C33H5.16 Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of human PTPN7 (protein tyrosine phosphatase non-receptor type 7). WB:WBGene00016383 zgpa-1 Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human ZGPAT (zinc finger CCCH-type and G-patch domain containing). WB:WBGene00016384 cdgs-1 Predicted to enable phosphatidate cytidylyltransferase activity. Predicted to be involved in CDP-diacylglycerol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Expressed in head and tail. Is an ortholog of human CDS1 (CDP-diacylglycerol synthase 1) and CDS2 (CDP-diacylglycerol synthase 2). WB:WBGene00016386 tag-272 Enriched in GLR; head mesodermal cell; pharyngeal cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00016387 kbp-5 Located in kinetochore. WB:WBGene00016388 C34B2.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00016389 C34B2.4 Predicted to enable metal ion binding activity. WB:WBGene00016390 ttc-1 Expressed in intestinal cell and neurons. Is predicted to encode a protein with the following domain: Tetratricopeptide-like helical domain superfamily. Is an ortholog of human TTC1 (tetratricopeptide repeat domain 1). WB:WBGene00016391 lonp-1 Predicted to enable ATP-dependent peptidase activity and single-stranded DNA binding activity. Involved in protein catabolic process. Predicted to be located in mitochondrial matrix. Expressed in head and tail. Human ortholog(s) of this gene implicated in CODAS syndrome. Is an ortholog of human LONP1 (lon peptidase 1, mitochondrial). WB:WBGene00016392 sdha-2 Predicted to enable electron transfer activity; flavin adenine dinucleotide binding activity; and succinate dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone). Human ortholog(s) of this gene implicated in several diseases, including Leigh disease; dilated cardiomyopathy 1GG; and mitochondrial complex II deficiency. Is an ortholog of human SDHA (succinate dehydrogenase complex flavoprotein subunit A). WB:WBGene00016393 ndua-13 Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Parkinson's disease; nuclear type mitochondrial complex I deficiency 28; and thyroid gland Hurthle cell carcinoma. Is an ortholog of human NDUFA13 (NADH:ubiquinone oxidoreductase subunit A13). WB:WBGene00016394 C34B2.9 Predicted to be located in membrane. WB:WBGene00016395 spcs-1 Involved in IRE1-mediated unfolded protein response. Located in endoplasmic reticulum. Is an ortholog of human SPCS1 (signal peptidase complex subunit 1). WB:WBGene00016396 C34B2.11 Predicted to be located in membrane. WB:WBGene00016397 maph-9 Predicted to enable microtubule binding activity. Predicted to be involved in mitotic spindle assembly and regulation of mitotic cytokinesis. Located in axoneme and ciliary base. Expressed in chemosensory neurons and ciliated neurons. Is an ortholog of human MAP9 (microtubule associated protein 9). WB:WBGene00016398 C34D4.2 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00016399 C34D4.3 Enriched in several structures, including NSM; amphid sheath cell; germ line; intestine; and sperm based on RNA-seq; tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty-one chemicals including Heme; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00016400 C34D4.4 Predicted to be involved in protein secretion and vesicle-mediated transport. Predicted to be located in membrane. Is an ortholog of human TVP23A (trans-golgi network vesicle protein 23 homolog A) and TVP23B (trans-golgi network vesicle protein 23 homolog B). WB:WBGene00016401 C34D4.5 No description available WB:WBGene00016402 C34D4.10 Enriched in arc ant V; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00016403 grsp-3 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and neurons based on Chronogram; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00016404 mutd-1 Involved in endosomal transport. Predicted to be located in transport vesicle. Predicted to be part of BLOC-1 complex. WB:WBGene00016405 hecd-1 Predicted to enable ubiquitin protein ligase activity. Involved in several processes, including determination of adult lifespan; hemidesmosome assembly; and regulation of Notch signaling pathway. Predicted to be located in nuclear speck. Is an ortholog of human HECTD1 (HECT domain E3 ubiquitin protein ligase 1). WB:WBGene00016406 C34D10.1 Predicted to be located in cytoplasm. Is an ortholog of human MOSPD1 (motile sperm domain containing 1). WB:WBGene00016407 unk-1 Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm. Is an ortholog of human UNKL (unk like zinc finger). WB:WBGene00016408 prmt-5 Enables DNA-binding transcription factor binding activity; p53 binding activity; and protein methyltransferase activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; negative regulation of DNA damage response, signal transduction by p53 class mediator; and response to odorant. Located in nucleus. Human ortholog(s) of this gene implicated in Leydig cell tumor and seminoma. Is an ortholog of human PRMT5 (protein arginine methyltransferase 5). WB:WBGene00016409 sumv-1 Located in cytoplasm; neuron projection; and nucleus. Expressed in hypodermis and neurons. Is an ortholog of human INO80D (INO80 complex subunit D). WB:WBGene00016410 C34E10.9 Enriched in RID and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00016411 C34E10.10 Predicted to enable small ribosomal subunit rRNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Is an ortholog of human UTP23 (UTP23 small subunit processome component). WB:WBGene00016412 mrps-26 Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS26 (mitochondrial ribosomal protein S26). WB:WBGene00016413 C34F11.1 Predicted to enable metal ion binding activity. WB:WBGene00016414 C34F11.2 Enriched in several structures, including excretory gland cell; germ line; neurons; retrovesicular ganglion; and sperm based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00016415 ampd-1 Predicted to enable AMP deaminase activity. Predicted to be involved in AMP metabolic process and IMP biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including congestive heart failure; hereditary spastic paraplegia 63; and pontocerebellar hypoplasia type 9. Is an ortholog of human AMPD2 (adenosine monophosphate deaminase 2). WB:WBGene00016416 C34F11.5 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 48 and severe combined immunodeficiency. Is an ortholog of human ZAP70 (zeta chain of T cell receptor associated protein kinase 70). WB:WBGene00016417 C34F11.8 Enriched in FLP; Z1; Z4; and hypodermis based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including rotenone; 4-bromodiphenyl ether; and Ag nanoparticles based on RNA-seq and microarray studies. WB:WBGene00016418 hpo-27 Predicted to be located in cytoplasm. Expressed in head and tail. Is an ortholog of human MROH1 (maestro heat like repeat family member 1). WB:WBGene00016419 tyr-4 Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human DCT (dopachrome tautomerase); TYR (tyrosinase); and TYRP1 (tyrosinase related protein 1). WB:WBGene00016420 C34G6.3 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including Ethanol; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00016421 cdc-7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including endocytosis; positive regulation of canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Is an ortholog of human CDC7 (cell division cycle 7). WB:WBGene00016422 noah-1 Involved in molting cycle. Predicted to be located in membrane. Expressed in vulA; vulB1; vulB2; vulC; and vulD. WB:WBGene00016423 tag-275 Predicted to enable metal ion binding activity and metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Is an ortholog of human ADAMDEC1 (ADAM like decysin 1). WB:WBGene00016424 C34H4.1 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00016425 C34H4.2 Enriched in OLL; PVD; head mesodermal cell; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-five chemicals including Heme; hydrogen sulfide; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00016427 C34H4.5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human ATMIN (ATM interactor). WB:WBGene00016428 dmsr-7 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00016429 C35A11.2 Enriched in arc ant V; hypodermis; pharyngeal cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by seventeen chemicals including stavudine; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00016430 C35A11.3 Enriched in CEM; HOB; IL2 neuron; ray neuron type B; and in male based on RNA-seq studies. Is affected by several genes including daf-2; csr-1; and mut-2 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00016431 C35A11.4 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. Is an ortholog of several human genes including SLC2A11 (solute carrier family 2 member 11); SLC2A5 (solute carrier family 2 member 5); and SLC2A9 (solute carrier family 2 member 9). WB:WBGene00016432 C35B1.2 Enriched in germ line; mechanosensory neurons; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; sir-2.1; and pmk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by paraquat; cadmium; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00016433 C35B1.3 Predicted to be located in membrane. WB:WBGene00016434 C35B1.4 Enriched in cephalic sheath cell; dopaminergic neurons; germ line; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including Ethanol; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00016435 C35B1.5 Predicted to be involved in photoreceptor cell maintenance and sensory perception. Is an ortholog of human NXNL2 (nucleoredoxin like 2). WB:WBGene00016436 C35B1.7 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00016437 C35B1.8 Is affected by several genes including daf-2; rrf-3; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Ethanol; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00016438 C35B8.3 Predicted to be located in mitochondrion. Is an ortholog of human TCAIM (T cell activation inhibitor, mitochondrial). WB:WBGene00016439 C35D10.1 Predicted to be located in membrane. Predicted to be part of EMC complex. Is an ortholog of human EMC7 (ER membrane protein complex subunit 7). WB:WBGene00016440 gipc-1 Expressed in spermatid. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 15 and oculopharyngodistal myopathy 2. Human GIPC1 enables signaling receptor binding activity. Is predicted to encode a protein with the following domains: PDZ domain-containing protein GIPC1/2/3; PDZ domain; and PDZ superfamily. Is an ortholog of human GIPC1 (GIPC PDZ domain containing family member 1) and GIPC3 (GIPC PDZ domain containing family member 3). WB:WBGene00016441 C35D10.3 Predicted to be located in membrane. WB:WBGene00016442 C35D10.5 Predicted to be involved in mitochondrial respiratory chain complex III assembly. Predicted to be located in mitochondrion. Is an ortholog of human UQCC1 (ubiquinol-cytochrome c reductase complex assembly factor 1). WB:WBGene00016443 C35D10.6 Predicted to enable oxidoreductase activity. WB:WBGene00016444 C35D10.7 Enriched in several structures, including ABalpppppa; ABplpaaaaa; AFD; g2; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00016445 C35D10.8 Predicted to be located in membrane. WB:WBGene00016446 C35D10.10 Predicted to enable disulfide oxidoreductase activity. Predicted to be located in membrane-bounded organelle. Is an ortholog of human TMX2 (thioredoxin related transmembrane protein 2). WB:WBGene00016447 msd-4 Located in cell body and pseudopodium. WB:WBGene00016448 C35D10.12 Predicted to enable tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity and tRNA binding activity. Predicted to be involved in tRNA methylation and tRNA wobble uridine modification. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human TRMT9B (tRNA methyltransferase 9B (putative)). WB:WBGene00016449 tost-1 Involved in positive regulation of cell division and positive regulation of chromosome segregation. Located in nucleus and perinuclear region of cytoplasm. WB:WBGene00016450 clec-5 Expressed in head. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00016451 clec-6 Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including CGP37157; paraquat; and cadmium based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00016452 C35D10.17 Predicted to be located in mitochondrion. Is an ortholog of human CMC2 (C-X9-C motif containing 2). WB:WBGene00016453 vet-2 Predicted to be involved in autophagy. Located in cytoplasm. WB:WBGene00016454 C35E7.2 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process and autophagy. WB:WBGene00016455 C35E7.3 Predicted to be involved in autophagy. WB:WBGene00016456 C35E7.4 Predicted to be involved in autophagy. Expressed in head neurons; intestine; tail neurons; and vulval muscle. WB:WBGene00016457 C35E7.5 Predicted to be involved in autophagy. WB:WBGene00016458 C35E7.6 Predicted to be involved in autophagy. Located in cytoplasm. WB:WBGene00016459 C35E7.7 Enriched in CEP; g2; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00016460 slfl-3 Located in endoplasmic reticulum. WB:WBGene00016461 C35E7.9 Predicted to be located in cytoskeleton. WB:WBGene00016462 C35E7.10 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00016463 C35E7.11 Expressed in RMFL; RMFR; RMHL; RMHR; and intestine. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00016464 C36B7.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cytoplasm; cytoskeleton; and nucleus. WB:WBGene00016465 C36B7.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cytoplasm; cytoskeleton; and nucleus. WB:WBGene00016466 C36B7.3 Predicted to be located in membrane. WB:WBGene00016467 C36B7.4 Predicted to be located in membrane. WB:WBGene00016468 C36B7.5 Enriched in ADEshL; ADEshR; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; D-glucose; and stavudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in X-linked properdin deficiency and factor VIII deficiency. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; Thrombospondin type 1 domain; and Thrombospondin type-1 (TSP1) repeat superfamily. Is an ortholog of human CFP (complement factor properdin). WB:WBGene00016469 C36B7.6 Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in endomembrane system and membrane. Is an ortholog of human CLPTM1 (CLPTM1 regulator of GABA type A receptor forward trafficking). WB:WBGene00016470 srab-5 Is affected by clk-1; eat-2; and hlh-26 based on microarray and RNA-seq studies. WB:WBGene00016471 srab-8 Predicted to be located in membrane. Expressed in amphid socket cell; neurons; and ray. WB:WBGene00016472 srbc-6 Predicted to be located in membrane. WB:WBGene00016473 C36C5.4 Enriched in AIBL; AIBR; and muscle cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00016474 exh-1 Enriched in several structures, including cephalic sheath cell; coelomocyte; muscle cell; neurons; and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; rotenone; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00016475 srab-9 Predicted to be located in membrane. Expressed in amphid neurons. WB:WBGene00016476 srab-10 Predicted to be located in membrane. Expressed in hypodermis. WB:WBGene00016477 srab-11 Predicted to be located in membrane. Expressed in chemosensory neurons. WB:WBGene00016478 srt-72 Enriched in NSM based on tiling array studies. Is affected by several genes including eat-2; tph-1; and pgl-1 based on tiling array and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00016479 srab-6 Predicted to be located in membrane. WB:WBGene00016480 srab-7 Predicted to be located in membrane. Expressed in amphid neurons and anal depressor muscle. WB:WBGene00016481 C36C5.12 Predicted to be located in membrane. WB:WBGene00016482 C36C5.13 No description available WB:WBGene00016483 C36C5.14 Expressed in body wall musculature; nerve ring; and neurons. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00016484 C36C5.15 Enriched in several structures, including cephalic sheath cell; coelomocyte; neurons; retrovesicular ganglion; and ventral nerve cord based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including npr-1; aak-2; and unc-30 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Tunicamycin; glycine; and cholesterol based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00016485 meg-4 Involved in P granule assembly; germ cell proliferation; and organelle localization. Located in P granule. Expressed in pharynx. WB:WBGene00016486 fbxa-170 Enriched in Y cell and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including bisphenol A; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00016487 C36C9.4 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by aldicarb and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1258) and Protein of unknown function DUF1258. WB:WBGene00016488 C36C9.5 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00016489 fubl-3 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA processing and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); liver cirrhosis; and malignant astrocytoma. Is an ortholog of human FUBP1 (far upstream element binding protein 1); FUBP3 (far upstream element binding protein 3); and KHSRP (KH-type splicing regulatory protein). WB:WBGene00016490 C36E6.2 Enriched in head mesodermal cell; intestine; neurons; and sensory neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-12; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; paraquat; and adsorbable organic bromine compound based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ig-like domain from next to BRCA1 gene; UBA-like superfamily; Immunoglobulin-like fold; Next to BRCA1, central domain; and UBA-like domain. Is an ortholog of human ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains). WB:WBGene00016491 acdh-5 Predicted to enable acyl-CoA dehydrogenase activity and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to be located in cytoplasm. WB:WBGene00016492 C37A2.6 Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in mitochondrial matrix. Is an ortholog of human ETFBKMT (electron transfer flavoprotein subunit beta lysine methyltransferase). WB:WBGene00016493 C37A2.7 Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translational elongation. Predicted to be located in cytosolic ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPLP2 (ribosomal protein lateral stalk subunit P2). WB:WBGene00016494 C37A2.8 Predicted to be located in nucleus. Is an ortholog of human CCDC174 (coiled-coil domain containing 174). WB:WBGene00016495 C37C3.1 Enriched in AFD; MSpaaaaa; body wall muscle cell; germ line; and nerve ring neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nine chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: YbiA-like superfamily; NADAR domain; and NADAR. WB:WBGene00016496 C37C3.2 Predicted to enable GDP-dissociation inhibitor activity; eukaryotic initiation factor eIF2 binding activity; and translation initiation factor activity. Involved in translation. Predicted to be located in cytosol. Is an ortholog of human EIF5 (eukaryotic translation initiation factor 5). WB:WBGene00016497 vps-32.2 Enriched in PLM; Y cell; intestine; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and let-7 based on tiling array; proteomic; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00016499 txt-5 Predicted to be located in membrane. WB:WBGene00016500 memo-1 Expressed in several structures, including gonad; neurons; pharynx; vulva; and vulval precursor cell. Is predicted to encode a protein with the following domains: MEMO1 family and Memo-like protein. Is an ortholog of human MEMO1 (mediator of cell motility 1). WB:WBGene00016501 C37C3.9 Enriched in AB; BAG; germ line; germline precursor cell; and nerve ring neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00016502 C37C3.10 Enriched in intestine based on tiling array studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including tryptophan; Tunicamycin; and mianserin based on microarray and RNA-seq studies. WB:WBGene00016503 C37C3.11 Predicted to be located in membrane. WB:WBGene00016504 C37C3.12 Predicted to be involved in protein import into nucleus. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human PTTG1IP (PTTG1 interacting protein). WB:WBGene00016505 ttr-33 Predicted to be located in cell surface and extracellular region. Expressed in head; hypodermis; pharynx; and posterior arcade cell. Used to study Parkinson's disease. WB:WBGene00016506 abhd-5.1 Predicted to enable carboxylic ester hydrolase activity and lysophosphatidic acid acyltransferase activity. Predicted to be involved in lipid homeostasis and phosphatidic acid biosynthetic process. Predicted to be located in lipid droplet and mitochondrion. Human ortholog(s) of this gene implicated in Chanarin-Dorfman syndrome; autosomal recessive congenital ichthyosis 1; and colon adenocarcinoma. Is an ortholog of human ABHD4 (abhydrolase domain containing 4, N-acyl phospholipase B) and ABHD5 (abhydrolase domain containing 5, lysophosphatidic acid acyltransferase). WB:WBGene00016507 abhd-5.2 Predicted to enable carboxylic ester hydrolase activity and lysophosphatidic acid acyltransferase activity. Predicted to be involved in lipid homeostasis and phosphatidic acid biosynthetic process. Predicted to be located in lipid droplet and mitochondrion. Expressed in hypodermis. Used to study Chanarin-Dorfman syndrome. Human ortholog(s) of this gene implicated in Chanarin-Dorfman syndrome; autosomal recessive congenital ichthyosis 1; and colon adenocarcinoma. Is an ortholog of human ABHD4 (abhydrolase domain containing 4, N-acyl phospholipase B) and ABHD5 (abhydrolase domain containing 5, lysophosphatidic acid acyltransferase). WB:WBGene00016508 C37H5.5 Predicted to enable chromatin binding activity. Predicted to be involved in DNA replication initiation. Predicted to be located in nucleolus. Is an ortholog of human NOC3L (NOC3 like DNA replication regulator). WB:WBGene00016509 adss-1 Predicted to enable adenylosuccinate synthase activity. Predicted to be involved in 'de novo' AMP biosynthetic process and IMP metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human ADSS1 (adenylosuccinate synthase 1). WB:WBGene00016511 C37H5.13 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid catabolic process. Predicted to be located in peroxisomal matrix. Is an ortholog of human ACOT8 (acyl-CoA thioesterase 8). WB:WBGene00016512 C38C3.3 Predicted to be located in ribosome. WB:WBGene00016513 C38C3.4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00016514 C38C3.6 Predicted to be located in membrane. WB:WBGene00016516 C38C3.8 Enriched in NSM; germ line; and in male based on RNA-seq and tiling array studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00016517 nhr-260 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in seam cell. WB:WBGene00016518 C38C5.1 Enriched in head mesodermal cell and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on microarray and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00016519 srz-56 Predicted to be located in membrane. Expressed in ADLL and ADLR. WB:WBGene00016520 C39B5.2 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ciliated neurons; male distal tip cell; and pharynx based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including 1-methylnicotinamide; methylmercuric chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00016521 fbxa-62 Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; glp-1; and daf-12 based on microarray and RNA-seq studies. Is affected by six chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00016522 fbxa-38 Enriched in ALNL; ALNR; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00016523 C39B5.5 Predicted to enable cysteine-type endopeptidase inhibitor activity. WB:WBGene00016524 C39B5.6 Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be part of glutamyl-tRNA(Gln) amidotransferase complex. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 41. Is an ortholog of human GATB (glutamyl-tRNA amidotransferase subunit B). WB:WBGene00016525 fbxa-12 Enriched in excretory cell based on tiling array studies. Is affected by several genes including clk-1; npr-1; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; antimycin; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00016526 fbxa-8 Is affected by several genes including eat-2; sir-2.1; and nhr-49 based on microarray and RNA-seq studies. Is affected by six chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00016527 fbxa-47 Enriched in OLL; PVD; and sensory neurons based on microarray and RNA-seq studies. Is affected by several genes including eat-2; clk-1; and tph-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; metformin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00016528 C39B5.10 Is affected by several genes including daf-2; nhr-49; and smg-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00016529 C39D10.1 Is affected by clk-1; rsr-2; and rrf-2 based on microarray and tiling array studies. Is affected by aldicarb and silicon dioxide nanoparticle based on microarray studies. WB:WBGene00016530 C39D10.2 Enriched in several structures, including ABalpppapa; ABplaapapa; ABplpaaaaa; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00016531 pcyt-2.2 Predicted to enable ethanolamine-phosphate cytidylyltransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be located in cytoplasm. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 82. Is an ortholog of human PCYT2 (phosphate cytidylyltransferase 2, ethanolamine). WB:WBGene00016532 C39D10.5 Expressed in nervous system. WB:WBGene00016533 latd-1 Predicted to be located in lysosomal membrane. WB:WBGene00016534 C39D10.7 Predicted to enable chitin binding activity. Predicted to be located in extracellular region. Expressed in germ line. WB:WBGene00016535 C39D10.8 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and sensory neurons based on microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including Ethanol; manganese chloride; and D-glucose based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: NTF2-like domain superfamily. WB:WBGene00016537 C39E6.2 Enriched in RID; Z1.p; Z4.a; gon_male_dtc anterior; and gon_male_dtc posterior based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; dpy-21; and let-418 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016538 C39F7.1 Predicted to be located in membrane. WB:WBGene00016539 madd-2 Enables protein homodimerization activity; signaling receptor binding activity; and ubiquitin-protein transferase activity. Involved in cell projection organization; protein ubiquitination; and regulation of protein localization. Located in several cellular components, including cell leading edge; neuronal cell body; and striated muscle dense body. Expressed in several structures, including anchor cell; intestinal cell; muscle cell; neurons; and ray precursor cell. Used to study Opitz GBBB syndrome. Human ortholog(s) of this gene implicated in Opitz GBBB syndrome; anencephaly; and non-syndromic X-linked intellectual disability 101. Is an ortholog of human TRIM67 (tripartite motif containing 67) and TRIM9 (tripartite motif containing 9). WB:WBGene00016540 C39F7.5 Predicted to be involved in morphogenesis of a branching epithelium. Is an ortholog of human BTBD7 (BTB domain containing 7). WB:WBGene00016541 ttbk-8.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00016542 C39H7.4 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00016543 srsx-14 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00016544 math-18 Enriched in AFD and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including bisphenol S; stavudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00016545 C40A11.2 Predicted to be involved in protein homooligomerization. Is an ortholog of human KCTD10 (potassium channel tetramerization domain containing 10) and TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00016546 C40A11.3 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00016547 C40A11.4 Predicted to be involved in protein homooligomerization. Is an ortholog of human KCTD13 (potassium channel tetramerization domain containing 13) and TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00016548 hpo-7 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00016549 C40A11.6 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00016550 C40A11.7 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00016551 C40A11.8 Predicted to be located in membrane. WB:WBGene00016552 C40A11.9 No description available WB:WBGene00016553 mir-8199 Enriched in GABAergic neurons; NSM; and head mesodermal cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016554 math-19 Is affected by several genes including daf-16; daf-2; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by dafa#1 based on microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00016555 math-20 Enriched in intestine based on tiling array; RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including rotenone; stavudine; and Rifampin based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00016556 math-21 Enriched in hyp3 and intestine based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00016557 ceh-84 Predicted to enable DNA binding activity. Predicted to be located in nucleus. WB:WBGene00016558 pks-1 Predicted to enable fatty acid synthase activity. Predicted to be involved in fatty acid biosynthetic process. Expressed in CANL and CANR. WB:WBGene00016559 C41A3.2 Enriched in coelomocyte; germ line; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00016561 eri-6 Expressed in ASIL; ASIR; ASKL; ASKR; and hypodermis. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1280) and Protein of unknown function DUF1280. WB:WBGene00016562 C41D11.3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in amphid neurons; body wall musculature; pharyngeal muscle cell; and uterine muscle. Is an ortholog of human CSRNP3 (cysteine and serine rich nuclear protein 3). WB:WBGene00016564 cmt-1 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalpapppa; ABalpppapa; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00016565 sosi-1 Predicted to enable RNA binding activity. Predicted to be involved in regulatory ncRNA-mediated heterochromatin formation. Predicted to be part of nuclear RNA-directed RNA polymerase complex. WB:WBGene00016566 eri-7 Predicted to enable RNA binding activity and transcription termination site sequence-specific DNA binding activity. Predicted to be involved in termination of RNA polymerase II transcription. Predicted to be located in nuclear body. Expressed in amphid neurons; gonad; and hypodermis. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 4; ataxia with oculomotor apraxia type 2; and hypertension. Is an ortholog of human MOV10 (Mov10 RNA helicase) and SETX (senataxin). WB:WBGene00016567 C41D11.9 Predicted to be located in membrane. Is an ortholog of human TM2D3 (TM2 domain containing 3). WB:WBGene00016568 C41G11.1 Predicted to enable hydrolase activity. WB:WBGene00016570 gnrr-4 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including chronic obstructive pulmonary disease; hypotrichosis 8; and pre-eclampsia. Is an ortholog of several human genes including F2R (coagulation factor II thrombin receptor); F2RL1 (F2R like trypsin receptor 1); and GPR4 (G protein-coupled receptor 4). WB:WBGene00016572 C41H7.2 Enriched in several structures, including ABalaapppa; AVG; RIM; command interneuron; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including rotenone; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016573 lido-12 Predicted to be located in nucleus. WB:WBGene00016574 lido-11 Predicted to be located in nucleus. WB:WBGene00016575 lido-10 Predicted to be located in nucleus. WB:WBGene00016576 lido-9 Predicted to be located in nucleus. WB:WBGene00016577 clec-3 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by forty chemicals including hydrogen sulfide; Ethanol; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00016578 sdz-5 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalapppaa; ABalppappa; and amphid neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; rotenone; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00016579 sre-14 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00016580 ppm-1.H Predicted to enable [pyruvate dehydrogenase (lipoamide)] phosphatase activity. Predicted to be located in mitochondrion. Is an ortholog of human PPM1J (protein phosphatase, Mg2+/Mn2+ dependent 1J). WB:WBGene00016581 C42C1.3 Enriched in NSM; Z1.p; Z4.a; germ line; and male distal tip cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including cholesterol; paraquat; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00016582 vps-8 Predicted to be involved in endosomal vesicle fusion and protein targeting to vacuole. Predicted to be located in late endosome. Predicted to be part of HOPS complex. Is an ortholog of human VPS8 (VPS8 subunit of CORVET complex). WB:WBGene00016583 tag-335 Predicted to enable mannose-1-phosphate guanylyltransferase (GTP) activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2T; congenital muscular dystrophy-dystroglycanopathy A14; and muscular dystrophy-dystroglycanopathy type B14. Is an ortholog of human GMPPB (GDP-mannose pyrophosphorylase B). WB:WBGene00016585 oac-59 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. Expressed in amphid neurons and hypodermis. WB:WBGene00016586 C42C1.8 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC49A3 (solute carrier family 49 member 3). WB:WBGene00016587 C42C1.9 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00016588 hpo-12 Predicted to enable thiamine transmembrane transporter activity. Predicted to be involved in thiamine pyrophosphate transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in inherited metabolic disorder and microcephaly. Is an ortholog of human SLC25A19 (solute carrier family 25 member 19). WB:WBGene00016589 ltah-1.1 Enables aminopeptidase activity. Involved in peptide catabolic process. Located in cytosol. Is an ortholog of human LTA4H (leukotriene A4 hydrolase). WB:WBGene00016590 C42C1.12 Enriched in several structures, including ABplpaaaap; AFD; I5 neuron; cholinergic neurons; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; let-60; and sir-2.1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; metformin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00016591 C42C1.13 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human VCPKMT (valosin containing protein lysine methyltransferase). WB:WBGene00016592 erl-1 Predicted to enable cholesterol binding activity. Predicted to be involved in SREBP signaling pathway. Located in endoplasmic reticulum membrane and protein-containing complex. Expressed in gonad. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 18 and hereditary spastic paraplegia 62. Is an ortholog of human ERLIN1 (ER lipid raft associated 1) and ERLIN2 (ER lipid raft associated 2). WB:WBGene00016594 srlf-7 Enriched in several structures, including AVA; excretory gland cell; head mesodermal cell; nerve ring neurons; and pharyngeal muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including 1-methylnicotinamide; rotenone; and juglone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain; SXP/RAL-2 family protein Ani s 5-like, metal-binding domain; and Phosphorylation site. WB:WBGene00016595 cest-10 Predicted to be located in membrane. WB:WBGene00016596 C42D4.3 Expressed in hypodermis; spermatheca; and vulva. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00016597 clec-179 Enriched in neurons and in male based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including set-2; drh-3; and let-418 based on tiling array and RNA-seq studies. Is affected by Acrylamide based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; C-type lectin fold; and PAN-3 domain. WB:WBGene00016598 C42D4.13 Enriched in NSM; germline precursor cell; hypodermis; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including methylmercury hydroxide; 1-methylnicotinamide; and stavudine based on RNA-seq and microarray studies. WB:WBGene00016599 C42D8.1 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00016600 ets-5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in nervous system. Is an ortholog of human FEV (FEV transcription factor, ETS family member). WB:WBGene00016601 acin-1 Predicted to enable RNA binding activity. Involved in gonad morphogenesis and regulation of cell migration. Predicted to be part of ASAP complex. Is an ortholog of human ACIN1 (apoptotic chromatin condensation inducer 1). WB:WBGene00016602 mus-81 Enables enzyme binding activity. Involved in several processes, including DNA recombination; larval development; and positive regulation of embryonic development. Predicted to be located in nucleus. Predicted to be part of Holliday junction resolvase complex. Is an ortholog of human MUS81 (MUS81 structure-specific endonuclease subunit). WB:WBGene00016603 met-1 Enables histone H3K36 methyltransferase activity. Involved in negative regulation of transcription by RNA polymerase II and negative regulation of vulval development. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed in hypodermis; intestine; and muscle cell. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and idiopathic pulmonary fibrosis. Is an ortholog of human SETD2 (SET domain containing 2, histone lysine methyltransferase). WB:WBGene00016605 C43E11.5 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00016606 exoc-7 Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in exocytosis. Predicted to be located in cis-Golgi network and membrane. Predicted to be part of exocyst. Expressed in several structures, including intestine; pharynx; somatic nervous system; tail neurons; and vulva. Is an ortholog of human EXOC7 (exocyst complex component 7). WB:WBGene00016607 C43E11.9 Predicted to enable RNA binding activity. Predicted to be involved in ribosomal large subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human NIP7 (nucleolar pre-rRNA processing protein NIP7). WB:WBGene00016608 cogc-5 Predicted to be involved in intra-Golgi vesicle-mediated transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be part of Golgi transport complex. Expressed in gonad. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIi. Is an ortholog of human COG5 (component of oligomeric golgi complex 5). WB:WBGene00016609 C43E11.12 Enriched in germ line; intestinal muscle; neurons; and rectal muscle based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including rotenone; Cry5B; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Transcription factor TFIIIC, triple barrel domain and TFIIIC subunit triple barrel domain. WB:WBGene00016610 paqr-1 Predicted to enable signaling receptor activity. Involved in positive regulation of fatty acid oxidation. Predicted to be located in plasma membrane. Expressed in excretory canal; gonadal sheath cell; mechanosensory neurons; and pharyngeal gland cell. Human ortholog(s) of this gene implicated in several diseases, including non-alcoholic fatty liver disease; obesity; and type 2 diabetes mellitus. Is an ortholog of human ADIPOR1 (adiponectin receptor 1). WB:WBGene00016611 bicd-1 Predicted to enable dynactin binding activity and dynein complex binding activity. Involved in regulation of dendrite morphogenesis. Located in dendrite and neuronal cell body. Expressed in several structures, including hypodermal cell; intestine; neurons; non-striated muscle; and pharyngeal-intestinal valve. Human ortholog(s) of this gene implicated in spinal muscular atrophy with lower extremity predominant 2A and spinal muscular atrophy with lower extremity predominant 2B. Is an ortholog of human BICD1 (BICD cargo adaptor 1). WB:WBGene00016612 C43G2.3 Enriched in several structures, including ABalpapaap; ABarappaap; RMED; germ line; and interfacial epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00016613 best-9 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of human BEST1 (bestrophin 1) and BEST3 (bestrophin 3). WB:WBGene00016614 trpp-12 Predicted to be located in Golgi apparatus. Predicted to be part of TRAPP complex. Is an ortholog of human TRAPPC12 (trafficking protein particle complex subunit 12). WB:WBGene00016616 mtpn-1 Predicted to be involved in regulation of barbed-end actin filament capping. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Is an ortholog of human MTPN (myotrophin). WB:WBGene00016617 C43H6.4 Enriched in neurons; rectal epithelial cell; rectum; seam cell; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eight chemicals including 1-methylnicotinamide; rotenone; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Armadillo-type fold. WB:WBGene00016619 C43H6.6 Predicted to be located in membrane. WB:WBGene00016620 dhhc-9 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Is an ortholog of human ZDHHC16 (zinc finger DHHC-type palmitoyltransferase 16). WB:WBGene00016621 arch-1 Predicted to enable metal ion binding activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be part of tRNA-splicing ligase complex. Is an ortholog of human ZBTB8OS (zinc finger and BTB domain containing 8 opposite strand). WB:WBGene00016622 mafr-1 Predicted to enable RNA polymerase III core binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase III. Located in cytoplasm and nucleus. Expressed in hypodermis and intestine. Is an ortholog of human MAF1 (MAF1 homolog, negative regulator of RNA polymerase III). WB:WBGene00016623 psmd-9 Predicted to be involved in proteasome regulatory particle assembly. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human PSMD9 (proteasome 26S subunit, non-ATPase 9). WB:WBGene00016624 hrpl-1 Predicted to enable mRNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including Sertoli cell-only syndrome; hepatocellular carcinoma; and systemic scleroderma. Is an ortholog of human HNRNPLL (heterogeneous nuclear ribonucleoprotein L like). WB:WBGene00016625 aff-1 Involved in regulation of egg-laying behavior and syncytium formation by plasma membrane fusion. Located in plasma membrane. Expressed in anchor cell; egg-laying apparatus; epithelial cell; neurons; and pharyngeal muscle cell. WB:WBGene00016626 clhm-1 Enables voltage-gated calcium channel activity. Involved in calcium ion transmembrane transport and regulation of locomotion. Located in non-motile cilium and plasma membrane. Expressed in body wall musculature; head; sensory neurons; and spermatheca. Is an ortholog of human CALHM5 (calcium homeostasis modulator family member 5) and CALHM6 (calcium homeostasis modulator family member 6). WB:WBGene00016627 C44B7.5 Predicted to be located in extracellular region. WB:WBGene00016628 slc-36.5 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in vacuolar membrane. Human ortholog(s) of this gene implicated in iminoglycinuria. Is an ortholog of several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A4 (solute carrier family 36 member 4). WB:WBGene00016629 C44B7.7 Predicted to enable gamma-glutamylcyclotransferase activity. Predicted to be located in membrane. Is an ortholog of human GGCT (gamma-glutamylcyclotransferase). WB:WBGene00016630 acer-1 Predicted to enable acetate CoA-transferase activity and acetyl-CoA hydrolase activity. Predicted to be involved in acetate metabolic process. Expressed in several structures, including germ line. WB:WBGene00016631 C44B7.11 Predicted to enable metal ion binding activity and metalloexopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human ERMP1 (endoplasmic reticulum metallopeptidase 1). WB:WBGene00016632 adal-1 Predicted to enable adenosine deaminase activity. Predicted to be involved in adenosine catabolic process and inosine biosynthetic process. Is an ortholog of human ADAL (adenosine deaminase like). WB:WBGene00016633 C44B11.1 Predicted to be involved in I-kappaB kinase/NF-kappaB signaling; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and positive regulation of neurogenesis. Is an ortholog of human FAIM (Fas apoptotic inhibitory molecule). WB:WBGene00016634 C44B11.4 Enriched in ABaraappaa and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00016635 C44B11.6 Enriched in several structures, including ABalapapapa; MSpppaaa; head mesodermal cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016636 perm-2 Expressed in oocyte. WB:WBGene00016637 C44B12.3 Enriched in several structures, including GLR; body muscle cell; cholinergic neurons; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and csr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00016638 perm-4 Expressed in oocyte. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00016639 C44B12.6 Predicted to enable cytokine activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. WB:WBGene00016640 C44B12.7 No description available WB:WBGene00016641 C44C1.1 Predicted to be located in membrane. WB:WBGene00016642 chil-10 Predicted to enable oligosaccharide binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in endomembrane system. Expressed in head. Is an ortholog of human CHID1 (chitinase domain containing 1). WB:WBGene00016643 vps-45 Involved in pinocytosis and receptor-mediated endocytosis. Predicted to be located in Golgi membrane. Expressed in several structures, including coelomocyte; head; hypodermis; intestine; and muscle cell. Human ortholog(s) of this gene implicated in severe congenital neutropenia 5. Is an ortholog of human VPS45 (vacuolar protein sorting 45 homolog). WB:WBGene00016644 abhd-3.2 Predicted to enable acetylesterase activity and acylglycerol lipase activity. Predicted to be involved in medium-chain fatty acid biosynthetic process and medium-chain fatty acid catabolic process. Is an ortholog of human ABHD1 (abhydrolase domain containing 1) and ABHD3 (abhydrolase domain containing 3, phospholipase). WB:WBGene00016645 C44C1.6 Enriched in mc2DL; mc2DR; mc2V; and mc3 based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including rotenone; Tunicamycin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00016646 fbxc-5 Enriched in intestine and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016647 fbxc-4 Enriched in intestine and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including D-glucopyranose; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016648 fbxc-2 Enriched in intestine and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including D-glucopyranose; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016649 fbxc-1 Enriched in intestine and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016650 ubr-4 Predicted to enable zinc ion binding activity. Predicted to be involved in DNA replication. Is an ortholog of human UBR4 (ubiquitin protein ligase E3 component n-recognin 4). WB:WBGene00016652 got-2.1 Predicted to enable L-aspartate:2-oxoglutarate aminotransferase activity. Predicted to be involved in aspartate catabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 82. Is an ortholog of human GOT2 (glutamic-oxaloacetic transaminase 2). WB:WBGene00016653 ssb-1 Predicted to enable mRNA binding activity. Predicted to be involved in positive regulation of translation and tRNA processing. Predicted to be located in cytoplasmic stress granule; cytosol; and nucleus. Predicted to be part of ribonucleoprotein complex. Expressed in head and tail. Is an ortholog of human SSB (small RNA binding exonuclease protection factor La). WB:WBGene00016654 C44E4.5 Predicted to be located in cytoplasm and nucleus. Is an ortholog of human NUDCD1 (NudC domain containing 1). WB:WBGene00016655 acbp-1 Predicted to enable long-chain fatty acyl-CoA binding activity. Involved in determination of adult lifespan and lipid storage. Is an ortholog of human DBI (diazepam binding inhibitor, acyl-CoA binding protein). WB:WBGene00016657 C44E12.1 Predicted to enable hydrolase activity. WB:WBGene00016658 C45B2.1 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00016659 C45B2.2 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00016660 C45B2.3 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00016661 C45B2.6 Predicted to enable calcium-independent phospholipase A2 activity and palmitoyl-CoA hydrolase activity. Predicted to be involved in positive regulation of ceramide biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including Duchenne muscular dystrophy; Parkinson's disease 14; dystonia 12; and neurodegeneration with brain iron accumulation (multiple). Is an ortholog of human PLA2G6 (phospholipase A2 group VI). WB:WBGene00016662 C45B2.8 Enriched in AFD; GABAergic neurons; excretory cell; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including methylmercury hydroxide; Tunicamycin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00016663 C45E1.4 Enriched in intestine; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by seven chemicals including rotenone; Zidovudine; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00016664 C45E5.1 Predicted to enable phosphatase activity. Predicted to be located in cytoplasm. Is an ortholog of human PDXP (pyridoxal phosphatase) and PGP (phosphoglycolate phosphatase). WB:WBGene00016665 chil-11 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. WB:WBGene00016666 C45E5.3 Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016667 cpg-18 Enriched in ABalpppppp; ABpraaappp; OLL; PVD; and pharynx based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including Heme; Mercuric Chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00016668 ilys-1 Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-positive bacterium. Expressed in intestine; mc1; mc2; pm3; and pm4. WB:WBGene00016669 ilys-2 Predicted to enable lysozyme activity. Involved in defense response to Gram-positive bacterium. Expressed in nerve ring and pm3. WB:WBGene00016670 ilys-3 Enables lysozyme activity. Involved in antibacterial innate immune response and defense response to Gram-positive bacterium. Located in late endosome lumen; lysosomal lumen; and recycling endosome lumen. Expressed in coelomocyte; hypodermis; intestinal cell; and terminal bulb. WB:WBGene00016671 C45G7.4 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. WB:WBGene00016673 ttbk-6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Expressed in ASKL; ASKR; amphid neurons; and neurons. WB:WBGene00016674 C45G9.2 Predicted to enable tRNA dihydrouridine synthase activity. Predicted to be involved in tRNA dihydrouridine synthesis. Is an ortholog of human DUS4L (dihydrouridine synthase 4 like). WB:WBGene00016675 C45G9.4 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Ethanol; methylmercuric chloride; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00016676 C45G9.5 Enriched in several structures, including SMB; coelomocyte; germ line; rectal epithelial cell; and sensory neurons based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; proteomic; and RNA-seq studies. Is affected by six chemicals including D-glucose; paraquat; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00016677 C45G9.6 Enriched in several structures, including ABplppppaa; ABprppppaa; ALN; rectal epithelial cell; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; mianserin; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00016678 txbp-3 Enriched in several structures, including excretory cell; germ line; interfacial epithelial cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; daf-12; and sir-2.1 based on microarray; RNA-seq; and tiling array studies. Is affected by eleven chemicals including hydrogen sulfide; rotenone; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PDZ domain; Tax1-binding protein 3; and PDZ superfamily. Is an ortholog of human TAX1BP3 (Tax1 binding protein 3). WB:WBGene00016679 C45G9.8 Enriched in AIB and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including eat-2; daf-18; and csr-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00016680 C45G9.9 Enriched in germ line; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00016681 C45G9.10 Enriched in germ line; male-specific anatomical entity; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on RNA-seq; proteomic; and microarray studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00016682 C45G9.11 Expressed in intestine. WB:WBGene00016683 C45G9.12 Enriched in OLL; RIM; hypodermis; and interneuron based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Tunicamycin; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00016684 nlp-43 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00016685 srbc-16 Predicted to be located in membrane. WB:WBGene00016686 cyp-33C1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00016687 srbc-17 Predicted to be located in membrane. WB:WBGene00016688 srbc-18 Enriched in DA neuron and VA neuron based on tiling array studies. Is affected by several genes including clk-1; drh-3; and rsr-2 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00016689 srbc-21 Predicted to be located in membrane. WB:WBGene00016690 srbc-22 Predicted to be located in membrane. WB:WBGene00016691 srbc-23 Predicted to be located in membrane. WB:WBGene00016692 srbc-24 Predicted to be located in membrane. WB:WBGene00016693 srbc-20 Predicted to be located in membrane. WB:WBGene00016694 C45H4.13 Is affected by several genes including csr-1; mex-1; and smg-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00016695 C45H4.14 Expressed in germ line. WB:WBGene00016696 srbc-19 Predicted to be located in membrane. WB:WBGene00016697 cyp-33C2 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including Keshan disease; autoimmune disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2A7 (cytochrome P450 family 2 subfamily A member 7); CYP2B6 (cytochrome P450 family 2 subfamily B member 6); and CYP2C19 (cytochrome P450 family 2 subfamily C member 19). WB:WBGene00016698 C46A5.1 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00016699 del-7 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Expressed in NSML and NSMR. WB:WBGene00016700 C46A5.4 Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. WB:WBGene00016701 dsb-3 Enriched in several structures, including ABaraapapaa; ABaraapppaa; CAN; germ line; and serotonergic neurons based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including manganese chloride; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016702 C46A5.6 Enriched in several structures, including NSM; RIM; germ line; head mesodermal cell; and interneuron based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray; proteomic; and RNA-seq studies. Is affected by thirteen chemicals including rotenone; manganese chloride; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00016703 rdl-1 Expressed in BAG and amphid neurons. Is predicted to encode a protein with the following domains: RD3 protein; Retinal degeneration protein 3; and Phosphorylation site. WB:WBGene00016704 hosl-1 Predicted to enable sterol esterase activity and triglyceride lipase activity. Predicted to be involved in triglyceride catabolic process. Predicted to be located in cytosol. Expressed in tail. Human ortholog(s) of this gene implicated in artery disease (multiple); familial partial lipodystrophy type 6; and type 2 diabetes mellitus. Is an ortholog of human LIPE (lipase E, hormone sensitive type). WB:WBGene00016705 slcr-46.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC46A2 (solute carrier family 46 member 2). WB:WBGene00016706 C46C11.3 Predicted to be located in plasma membrane. WB:WBGene00016707 C46E10.1 Enriched in amphid sheath cell; germ line; and in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00016708 C46E10.2 Enriched in neurons based on RNA-seq studies. Is affected by cyc-1; rsr-2; and sir-2.1 based on microarray and tiling array studies. Is affected by fluoranthene based on microarray studies. WB:WBGene00016709 C46E10.3 Is affected by rsr-2 and csr-1 based on tiling array and RNA-seq studies. Is affected by dibromoacetic acid based on microarray studies. WB:WBGene00016710 fbxc-52 Enriched in several structures, including ABalpppapa; ABplpaaaaa; male distal tip cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Cry5B; allantoin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557; Domain of unknown function (DUF3557); and Phosphorylation site. WB:WBGene00016711 fbxc-53 Enriched in several structures, including ABalpppapa; ABalpppappp; ABalppppapa; ABalpppppa; and amphid neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00016712 C46E10.8 Expressed in dorsal nerve cord; head neurons; tail neurons; and ventral nerve cord. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type; Zinc-finger of C2H2 type; Zinc finger C2H2 superfamily; and C2H2-type zinc finger. WB:WBGene00016713 C46E10.9 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00016714 C46F2.1 Enriched in several structures, including GLR; MSpppaaa; coelomocyte; head mesodermal cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including rotenone; mianserin; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00016716 acs-17 Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process; long-chain fatty-acyl-CoA metabolic process; and neuron differentiation. Predicted to be located in endoplasmic reticulum; lipid droplet; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including lung cancer; non-syndromic X-linked intellectual disability 63; and prostate cancer. Is an ortholog of human ACSL3 (acyl-CoA synthetase long chain family member 3) and ACSL4 (acyl-CoA synthetase long chain family member 4). WB:WBGene00016717 math-22 Enriched in ASER and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Tunicamycin; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00016718 math-23 Is affected by several genes including lin-15B; met-2; and spr-5 based on microarray and RNA-seq studies. Is affected by four chemicals including Tunicamycin; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00016719 math-24 Enriched in intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Rifampin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00016720 math-25 Is affected by several genes including lin-4; lin-14; and smn-1 based on tiling array; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00016721 C46G7.1 Predicted to enable RNA endonuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis and obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. Predicted to be located in membrane. Is an ortholog of human RNASEK (ribonuclease K). WB:WBGene00016722 C46G7.2 Located in A band and striated muscle dense body. Expressed in body wall musculature and vulval muscle. WB:WBGene00016723 C46G7.3 No description available WB:WBGene00016724 C46H3.1 Enriched in ASI; ASIL; ASIR; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00016725 C46H3.2 Enriched in several structures, including ABplpaaaap; accessory cell; germ line; neurons; and rect_D based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including stavudine; allantoin; and Rifampin based on RNA-seq and microarray studies. Human CASKIN1 enables identical protein binding activity. Is predicted to encode a protein with the following domains: SAM domain (Sterile alpha motif); Sterile alpha motif/pointed domain superfamily; and Sterile alpha motif domain. Is an ortholog of human CASKIN1 (CASK interacting protein 1) and CASKIN2 (CASK interacting protein 2). WB:WBGene00016727 C46H11.1 Enriched in neurons based on tiling array studies. Is affected by several genes including set-2; ubc-9; and etr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Atrazine; copper sulfate; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00016728 C46H11.2 Predicted to enable flavin adenine dinucleotide binding activity and monooxygenase activity. Predicted to be located in cytosol. WB:WBGene00016729 C46H11.3 Predicted to enable actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation and cell migration. Predicted to be located in cytoplasm. Predicted to be part of Arp2/3 protein complex. Human ortholog(s) of this gene implicated in lung squamous cell carcinoma. Is an ortholog of human ARPC5 (actin related protein 2/3 complex subunit 5) and ARPC5L (actin related protein 2/3 complex subunit 5 like). WB:WBGene00016730 C46H11.6 Expressed in anal depressor muscle; body wall musculature; intestine; and vulval muscle. Is predicted to encode a protein with the following domain: Uncharacterized protein T15H9.4-like. WB:WBGene00016731 C46H11.7 Enriched in g1P and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including stavudine; Zidovudine; and cholesterol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00016732 phat-1 Involved in pharyngeal gland morphogenesis. Expressed in pharyngeal gland cell. WB:WBGene00016733 phat-2 Involved in pharyngeal gland morphogenesis. Expressed in g1AL; g1AR; g1P; g2L; and g2R. WB:WBGene00016734 C46H11.10 Enriched in head mesodermal cell; muscle cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00016735 fhod-1 Predicted to enable actin filament binding activity. Involved in actin filament organization and embryonic body morphogenesis. Located in actin cytoskeleton. Expressed in muscle cell; pharyngeal muscle cell; and seam cell. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy. Is an ortholog of human FHOD1 (formin homology 2 domain containing 1) and FHOD3 (formin homology 2 domain containing 3). WB:WBGene00016737 miro-2 Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. WB:WBGene00016738 C47D2.1 Enriched in head mesodermal cell; intestine; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including pgl-1; aak-2; and isp-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00016739 pitr-1 Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Expressed in several structures, including body wall musculature; hermaphrodite gonad; intestine; nerve ring; and pharynx. Human ortholog(s) of this gene implicated in basal ganglia calcification. Is an ortholog of human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2). WB:WBGene00016740 C48B6.2 Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of Mpp10 complex and small-subunit processome. Expressed in head neurons and pharyngeal muscle cell. Is an ortholog of human IMP3 (IMP U3 small nucleolar ribonucleoprotein 3). WB:WBGene00016741 haps-1 Predicted to be located in nucleus. Expressed in germ line. Is an ortholog of human HAPSTR1 (HUWE1 associated protein modifying stress responses). WB:WBGene00016742 C48B6.4 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00016743 srb-15 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00016744 bbs-9 Predicted to be involved in cilium assembly. Located in ciliary basal body. Used to study Bardet-Biedl syndrome. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 9; craniosynostosis; and primary ovarian insufficiency. Is an ortholog of human BBS9 (Bardet-Biedl syndrome 9). WB:WBGene00016745 C48B6.9 Predicted to be located in membrane. WB:WBGene00016746 C48B6.10 Predicted to be located in membrane. WB:WBGene00016747 nmur-1 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. Expressed in head neurons. Is an ortholog of human NMUR1 (neuromedin U receptor 1) and NMUR2 (neuromedin U receptor 2). WB:WBGene00016748 aexr-3 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00016749 C48E7.1 Predicted to be located in membrane. WB:WBGene00016750 let-611 Predicted to enable single-stranded DNA binding activity. Predicted to be involved in DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is an ortholog of human POLR3C (RNA polymerase III subunit C). WB:WBGene00016751 C48E7.6 Predicted to be involved in anatomical structure morphogenesis. Predicted to be located in collagen-containing extracellular matrix. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia and relapsing-remitting multiple sclerosis. Is an ortholog of human CSPG4 (chondroitin sulfate proteoglycan 4). WB:WBGene00016752 C48E7.7 Enriched in several structures, including CEP socket cell; amphid sheath cell; germ line; intestine; and sperm based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Ethanol; methylmercuric chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00016753 oac-9 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00016754 cebp-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to Gram-negative bacterium; regulation of lipid metabolic process; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in somatic cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; hepatocellular carcinoma; and rheumatoid arthritis. Is an ortholog of human CEBPG (CCAAT enhancer binding protein gamma). WB:WBGene00016755 C49A9.1 Enriched in intestine based on RNA-seq studies. Is affected by several genes including elt-2; clk-1; and eri-1 based on microarray and RNA-seq studies. Is affected by four chemicals including stearic acid; sucrose; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF272) and Protein of unknown function DUF272. WB:WBGene00016756 C49A9.2 Enriched in DVA; DVC; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including aldicarb; D-glucose; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF272); Protein of unknown function DUF272; and Phosphorylation site. WB:WBGene00016757 C49A9.3 Enriched in g1P and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and let-60 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including D-glucopyranose; bisphenol A; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF272) and Protein of unknown function DUF272. WB:WBGene00016758 C49A9.4 Enriched in RIV; head mesodermal cell; intestine; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF272) and Protein of unknown function DUF272. WB:WBGene00016759 C49A9.5 Enriched in FLP; head mesodermal cell; intestine; and rectal gland cell based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including D-glucopyranose; bisphenol S; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF272) and Protein of unknown function DUF272. WB:WBGene00016760 C49A9.6 Enriched in head mesodermal cell; intestine; pharyngeal muscle cell; rectal gland cell; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; rrf-3; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including D-glucopyranose; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF272); Protein of unknown function DUF272; and Phosphorylation site. WB:WBGene00016761 tkr-2 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in exercise-induced bronchoconstriction and hypogonadotropic hypogonadism 11 with or without anosmia. Is an ortholog of human TACR2 (tachykinin receptor 2). WB:WBGene00016762 ugt-24 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00016763 C49A9.9 Enriched in head mesodermal cell; intestine; and rectal gland cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and let-60 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF272); Protein of unknown function DUF272; and Phosphorylation site. WB:WBGene00016764 C49A9.10 Enriched in several structures, including ABplapaaap; ABprapaaap; AFD; coelomocyte; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; npr-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; stavudine; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Oxidoreductase-like, N-terminal; Oxidoreductase-like domain-containing protein 1; and Oxidoreductase-like protein, N-terminal. Is an ortholog of human OXLD1 (oxidoreductase like domain containing 1). WB:WBGene00016765 C49C8.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00016766 C49C8.2 Predicted to be located in membrane. WB:WBGene00016767 C49C8.3 Enriched in AVK; germ line; germline precursor cell; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; manganese chloride; and mianserin based on RNA-seq and microarray studies. WB:WBGene00016768 cyp-33E1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including end stage renal disease; human immunodeficiency virus infectious disease; and renal hypertension. Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C8 (cytochrome P450 family 2 subfamily C member 8); and CYP2F1 (cytochrome P450 family 2 subfamily F member 1). WB:WBGene00016769 C49C8.5 Involved in innate immune response. Predicted to be located in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human ANGPT2 (angiopoietin 2) and ANGPT4 (angiopoietin 4). WB:WBGene00016770 C49C8.6 Enriched in pharyngeal-intestinal valve; pm6; pm7; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by sesamin; glycine; and adsorbable organic bromine compound based on microarray and RNA-seq studies. WB:WBGene00016771 C49D10.1 No description available WB:WBGene00016772 nhr-166 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons. Human ortholog(s) of this gene implicated in cholestasis (multiple); liver disease (multiple); and non-alcoholic steatohepatitis. Is an ortholog of human NR1H4 (nuclear receptor subfamily 1 group H member 4) and NR1I3 (nuclear receptor subfamily 1 group I member 3). WB:WBGene00016773 oac-10 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00016775 C49D10.7 Enriched in NSM and neurons based on tiling array and microarray studies. Is affected by several genes including clk-1; cyc-1; and ain-2 based on microarray and tiling array studies. Is affected by resveratrol; Atrazine; and Sirolimus based on microarray studies. WB:WBGene00016776 oac-11 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00016777 nhr-261 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016778 nep-3 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00016779 sdz-7 Enriched in ABalpapaap; ABarappaap; NSM; and Y cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and alg-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seventeen chemicals including tryptophan; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00016781 phat-7 Enriched in g1P; germ line; intestine; and mechanosensory neurons based on proteomic; tiling array; microarray; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Ethanol; rotenone; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00016782 phat-3 Involved in pharyngeal gland morphogenesis. Expressed in pharyngeal gland cell. WB:WBGene00016783 irg-2 Involved in antibacterial innate immune response and defense response to Gram-negative bacterium. WB:WBGene00016785 C49G7.7 Enriched in CEPshDL; CEPshDR; CEPshVL; and CEPshVR based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-six chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00016786 cyp-35A4 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). WB:WBGene00016788 C49G7.10 Involved in innate immune response. WB:WBGene00016789 djr-1.2 Predicted to enable glyoxalase III activity. Involved in cellular aldehyde metabolic process; cellular response to aldehyde; and monocarboxylic acid biosynthetic process. Located in cytoplasm. Expressed in several structures, including excretory canal; inner labial neurons; phasmid neurons; rectal gland cell; and ventral nerve cord. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease 7; Parkinsonism; and middle cerebral artery infarction. Is an ortholog of human PARK7 (Parkinsonism associated deglycase). WB:WBGene00016790 C49H3.3 Predicted to enable basal RNA polymerase II transcription machinery binding activity. Predicted to be involved in dendrite extension. Predicted to be located in nucleolus. Is an ortholog of human LLPH (LLP homolog, long-term synaptic facilitation factor). WB:WBGene00016791 C49H3.4 Predicted to enable U7 snRNA binding activity. Predicted to be involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Predicted to be part of U7 snRNP. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Is an ortholog of human LSM11 (LSM11, U7 small nuclear RNA associated). WB:WBGene00016792 C49H3.6 Located in cytoplasm. Expressed in intestinal muscle and ventral nerve cord. Is an ortholog of human CTTNBP2NL (CTTNBP2 N-terminal like). WB:WBGene00016793 arp-11 Predicted to be involved in retrograde axonal transport of mitochondrion. Part of dynactin complex. Is an ortholog of human ACTR10 (actin related protein 10). WB:WBGene00016794 npp-27 Predicted to enable zinc ion binding activity. Predicted to be located in nucleus. Is an ortholog of human ZC3HC1 (zinc finger C3HC-type containing 1). WB:WBGene00016795 C49H3.12 Enriched in AFD and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00016796 cec-2 Enriched in several structures, including AFD; amphid sheath cell; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Chromo/chromo shadow domain; Chromo-like domain superfamily; and Phosphorylation site. WB:WBGene00016797 C50A2.3 Predicted to be located in membrane. WB:WBGene00016798 ets-8 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human ETV1 (ETS variant transcription factor 1); ETV4 (ETS variant transcription factor 4); and ETV5 (ETS variant transcription factor 5). WB:WBGene00016799 C50C3.1 Predicted to enable metal ion binding activity. WB:WBGene00016800 C50C3.2 Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to be located in several cellular components, including cell junction; cortical actin cytoskeleton; and plasma membrane. WB:WBGene00016801 C50C3.5 Predicted to enable calcium ion binding activity. WB:WBGene00016803 bath-42 Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to be located in cytoplasm and nucleus. Expressed in intestine; pharyngeal muscle cell; seam cell; and vulval muscle. WB:WBGene00016804 C50C3.12 Is affected by rsr-2 and drh-3 based on tiling array and RNA-seq studies. WB:WBGene00016805 C50D2.1 Enriched in germline precursor cell; hypodermis; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq and microarray studies. WB:WBGene00016806 C50D2.2 Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in amino acid transport. Predicted to be located in plasma membrane. Expressed in head. Is an ortholog of human SLC7A4 (solute carrier family 7 member 4). WB:WBGene00016807 txt-1 Enriched in germ line; serotonergic neurons; and in male based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PDZ domain; Uncharacterized protein T15H9.4-like; and PDZ superfamily. WB:WBGene00016808 sftb-6 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and spliceosomal complex. Is an ortholog of human SF3B6 (splicing factor 3b subunit 6). WB:WBGene00016809 C50D2.6 Enriched in body wall musculature; intestine; neurons; retrovesicular ganglion; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by seven chemicals including bisphenol S; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00016810 C50D2.7 Predicted to enable ADP-specific glucokinase activity. Predicted to be involved in glucose metabolic process. Predicted to be located in endoplasmic reticulum. Is an ortholog of human ADPGK (ADP dependent glucokinase). WB:WBGene00016811 luc-7L3 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to be part of U1 snRNP and U2-type prespliceosome. Is an ortholog of human LUC7L3 (LUC7 like 3 pre-mRNA splicing factor). WB:WBGene00016812 mcat-1 Predicted to enable transferase activity. Predicted to be involved in fatty acid metabolic process. Is an ortholog of human MCAT (malonyl-CoA-acyl carrier protein transacylase). WB:WBGene00016813 clec-214 Enriched in ABalaapppp; ABalapaapp; ABalappppa; ABalppappp; and ABarappppp based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and tdp-1 based on tiling array and microarray studies. Is affected by six chemicals including resveratrol; dafa#1; and adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00016815 clec-213 Is affected by several genes including sir-2.1; ain-1; and mir-34 based on tiling array and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00016816 C50E3.5 Enriched in OLL; germ line; germline precursor cell; and interneuron based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and hsf-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including aldicarb; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00016817 C50E3.6 Enriched in neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including allantoin; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00016818 C50E3.7 Predicted to be located in membrane. WB:WBGene00016820 C50E3.9 Predicted to be located in membrane. WB:WBGene00016821 scl-26 Predicted to be located in extracellular space. WB:WBGene00016822 C50E3.11 Enriched in AVHL; AVHR; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; Zidovudine; and tert-Butylhydroperoxide based on RNA-seq and microarray studies. WB:WBGene00016823 C50E3.12 Enriched in AB and germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including D-glucose; bisphenol A; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00016824 C50E3.13 Enriched in AB; ABplpaaaap; ABprpaaaap; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including rotenone; D-glucose; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00016825 C50E10.1 Enriched in I5 neuron; cholinergic neurons; retrovesicular ganglion; sperm; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and gld-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-six chemicals including methylmercury hydroxide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00016826 C50E10.2 Enriched in Z1; Z4; and in male based on RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by eight chemicals including tryptophan; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1265 and Protein of unknown function (DUF1265). WB:WBGene00016827 sre-53 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head. WB:WBGene00016828 sre-52 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in PVT. WB:WBGene00016829 sre-54 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00016830 sre-55 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00016831 sre-56 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head. WB:WBGene00016832 sre-49 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00016833 sre-51 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Expressed in head neurons. WB:WBGene00016834 sre-50 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00016835 C50F2.1 Enriched in ABplpaaaaa and ABprpaaaaa based on single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including indole; Alovudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00016836 C50F2.2 Enriched in several structures, including MSaaaaapa; germ line; neurons; rectal epithelial cell; and rectum based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and npr-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00016837 syf-1 Predicted to be involved in generation of catalytic spliceosome for first transesterification step. Predicted to be part of Prp19 complex; U2-type catalytic step 2 spliceosome; and post-mRNA release spliceosomal complex. Expressed in head and tail. Is an ortholog of human XAB2 (XPA binding protein 2). WB:WBGene00016838 C50F2.4 Enriched in Cappppv; Cpppppv; body wall muscle cell; intestine; and muscle cell based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on tiling array; proteomic; RNA-seq; and microarray studies. Is affected by twelve chemicals including methylmercuric chloride; rotenone; and D-glucopyranose based on microarray and RNA-seq studies. WB:WBGene00016839 C50F2.5 Predicted to enable protein tyrosine phosphatase activity. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Is an ortholog of human PTPRG (protein tyrosine phosphatase receptor type G) and PTPRZ1 (protein tyrosine phosphatase receptor type Z1). WB:WBGene00016840 C50F2.7 Predicted to be located in membrane. WB:WBGene00016841 magu-3 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cell-cell junction and plasma membrane. Expressed in tail. Is an ortholog of human PALS2 (protein associated with LIN7 2, MAGUK p55 family member). WB:WBGene00016842 npr-35 Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in AIYL and AIYR. Is an ortholog of human NPFFR1 (neuropeptide FF receptor 1) and NPFFR2 (neuropeptide FF receptor 2). WB:WBGene00016843 C50F7.3 Enriched in B cell; somatic gonad precursor; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including aldicarb; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Uncharacterized protein T15H9.4-like. WB:WBGene00016844 sucg-1 Predicted to enable succinate-CoA ligase (GDP-forming) activity. Predicted to be involved in succinyl-CoA metabolic process and tricarboxylic acid cycle. Predicted to be located in mitochondrion. Predicted to be part of succinate-CoA ligase complex. Is an ortholog of human SUCLG2 (succinate-CoA ligase GDP-forming subunit beta). WB:WBGene00016845 C50F7.5 Enriched in cholinergic neurons; head mesodermal cell; intestine; mechanosensory neurons; and in male based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by forty-three chemicals including 1-methylnicotinamide; rotenone; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00016846 C50F7.6 Enriched in several structures, including ABplpppaaa; AFD; Caapa; PVP; and body wall musculature based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by eight chemicals including Zidovudine; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is an ortholog of human PDZRN4 (PDZ domain containing ring finger 4). WB:WBGene00016847 C50F7.9 Predicted to be located in membrane. WB:WBGene00016848 klo-1 Predicted to enable beta-glucosidase activity. Predicted to be involved in carbohydrate metabolic process. Expressed in excretory canal; excretory cell; and intestine. Used to study kidney disease. Human ortholog(s) of this gene implicated in several diseases, including end stage renal disease; intracranial embolism; and spondylosis. Is an ortholog of human GBA3 (glucosylceramidase beta 3 (gene/pseudogene)) and LCTL (lactase like). WB:WBGene00016849 acs-21 Predicted to enable medium-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty acid metabolic process. Human ortholog(s) of this gene implicated in combined malonic and methylmalonic acidemia. Is an ortholog of human ACSF3 (acyl-CoA synthetase family member 3). WB:WBGene00016850 srt-8 Predicted to be located in membrane. Expressed in ASIL and ASIR. WB:WBGene00016851 srt-71 Is affected by mir-34; eri-1; and let-60 based on microarray studies. WB:WBGene00016852 srt-7 Predicted to be located in membrane. Expressed in AWAL; AWAR; AWC-ON; and in male. WB:WBGene00016853 srt-9 Enriched in neurons based on RNA-seq studies. Is affected by mir-34 based on microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00016854 srt-10 Is affected by tatn-1 and etr-1 based on RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00016855 C50H11.8 Enriched in neurons and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; rrf-1; and prg-1 based on tiling array; RNA-seq; and microarray studies. Is affected by allantoin and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00016856 srt-15 Predicted to be located in membrane. WB:WBGene00016857 srt-16 Predicted to be located in membrane. WB:WBGene00016858 C50H11.13 Predicted to be located in membrane. WB:WBGene00016859 srt-5 Predicted to be located in membrane. WB:WBGene00016860 cyp-33C9 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00016861 C50H11.17 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including nhr-49; lin-15B; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by tryptophan; multi-walled carbon nanotube; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00016862 cest-32 Predicted to enable carboxylic ester hydrolase activity. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). WB:WBGene00016863 cest-35.2 Predicted to enable carboxylic ester hydrolase activity. Is an ortholog of human CES2 (carboxylesterase 2); CES3 (carboxylesterase 3); and CES5A (carboxylesterase 5A). WB:WBGene00016864 C52A10.3 Enriched in several structures, including ABarpapaapp; ABplaaaaapp; anal sphincter muscle; germ line; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00016865 ets-9 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hematologic cancer (multiple); and thrombocytopenia. Is an ortholog of several human genes including ETS1 (ETS proto-oncogene 1, transcription factor); ETS2 (ETS proto-oncogene 2, transcription factor); and ETV6 (ETS variant transcription factor 6). WB:WBGene00016866 coel-1 Predicted to enable alpha-tubulin binding activity. Predicted to be involved in microtubule cytoskeleton organization; post-chaperonin tubulin folding pathway; and tubulin complex assembly. Predicted to be located in cytoplasm. Expressed in head; tail neurons; and touch receptor neurons. Is an ortholog of human TBCEL (tubulin folding cofactor E like). WB:WBGene00016867 C52B9.4 Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be located in Golgi apparatus and membrane. Is an ortholog of human TMEM87B (transmembrane protein 87B). WB:WBGene00016868 C52B9.8 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00016869 C52B9.10 Enriched in intestine and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including alg-1; drh-3; and ubc-9 based on tiling array; microarray; and RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00016870 ets-10 Expressed in hypodermis; intestine; neurons; spermathecal cell; and uterine epithelial cell. Is predicted to encode a protein with the following domain: Winged helix DNA-binding domain superfamily. WB:WBGene00016871 inso-1 Predicted to enable cullin family protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in cell junction and striated muscle dense body. Human ortholog(s) of this gene implicated in myoclonic dystonia 26. Is an ortholog of human KCTD5 (potassium channel tetramerization domain containing 5). WB:WBGene00016872 dop-4 Enables dopamine neurotransmitter receptor activity. Involved in adenylate cyclase-activating dopamine receptor signaling pathway. Predicted to be located in dendrite. Expressed in intestine; neurons; rectum; and vulva. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Alzheimer's disease and hypertension. Is an ortholog of human ADRA1A (adrenoceptor alpha 1A) and ADRA1B (adrenoceptor alpha 1B). WB:WBGene00016873 C52B11.4 Is affected by several genes including dpy-10; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00016874 C52B11.5 Predicted to enable GTP binding activity and GTPase activity. WB:WBGene00016877 C52D10.3 Enriched in NSM; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4140; Domain of unknown function (DUF4139); Conserved hypothetical protein CHP02231; Domain of unknown function DUF4139; and N-terminal domain of unknown function (DUF4140). WB:WBGene00016878 C52D10.5 No description available WB:WBGene00016879 cnnm-1 Predicted to enable transmembrane transporter activity. Involved in several processes, including determination of adult lifespan; magnesium ion homeostasis; and positive regulation of developmental process. Located in basolateral plasma membrane. Expressed in several structures, including body wall musculature; hypodermis; intestine; pharynx; and rectum. Human ortholog(s) of this gene implicated in Jalili syndrome and renal hypomagnesemia 6. Is an ortholog of several human genes including CNNM1 (cyclin and CBS domain divalent metal cation transport mediator 1); CNNM3 (cyclin and CBS domain divalent metal cation transport mediator 3); and CNNM4 (cyclin and CBS domain divalent metal cation transport mediator 4). WB:WBGene00016880 fbxb-95 Enriched in ABplpappaa; cholinergic neurons; hypodermis; and interfacial epithelial cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; methylmercuric chloride; and indole based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00016881 C52E2.2 Enriched in MC neuron; MCL; MCR; cephalic sheath cell; and dopaminergic neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including rrf-3; sir-2.1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by Tunicamycin; Diazinon; and Sirolimus based on microarray studies. WB:WBGene00016882 C52E2.3 Is affected by several genes including sir-2.1; osm-3; and mut-2 based on microarray and RNA-seq studies. Is affected by four chemicals including aldicarb; Rifampin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00016883 C52E2.4 Enriched in AVKL; AVKR; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00016884 C52E2.5 Enriched in ABplapaaaa; ABprapaaaa; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Zidovudine; Rifampin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00016885 fbxb-97 Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including daf-2; pie-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00016886 fbxb-96 Predicted to be located in membrane. WB:WBGene00016887 C52E2.8 No description available WB:WBGene00016888 znf-598 Predicted to enable ribosome binding activity and ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and rescue of stalled ribosome. Is an ortholog of human ZNF598 (zinc finger protein 598, E3 ubiquitin ligase). WB:WBGene00016889 lst-6 Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 49. Is an ortholog of human DENND5A (DENN domain containing 5A) and DENND5B (DENN domain containing 5B). WB:WBGene00016890 lst-5 Predicted to enable chromatin insulator sequence binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome. Expressed in several structures, including P5.paa; P5.pap; P5.ppa; P5.ppp; and P7.paa. WB:WBGene00016891 C53A3.1 Enriched in Y cell; germ line; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00016892 pgph-3 Predicted to enable phosphatase activity. Predicted to be located in cytoplasm. Is an ortholog of human PDXP (pyridoxal phosphatase) and PGP (phosphoglycolate phosphatase). WB:WBGene00016893 C53B7.2 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00016894 C53B7.3 Enriched in several structures, including MSaaaaapa; head mesodermal cell; pharyngeal cell; pharyngeal-intestinal valve; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including hydrogen sulfide; rotenone; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00016895 C53B7.6 Is affected by several genes including daf-16; daf-2; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by methylmercuric chloride and Tunicamycin based on microarray studies. WB:WBGene00016896 nep-4 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00016898 clik-2 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to be located in actin cytoskeleton. WB:WBGene00016899 C53C11.1 Enriched in several structures, including ABalppappa; ABarappppa; FLP; germ line; and pharyngeal cell based on microarray; RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including allantoin; metformin; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Sterile alpha motif/pointed domain superfamily. WB:WBGene00016900 C53C11.2 Predicted to be located in membrane. WB:WBGene00016901 C53C11.4 Enriched in OLL and PVD based on microarray studies. Is affected by several genes including eat-2; mex-1; and dpy-21 based on RNA-seq studies. Is affected by aldicarb and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: GETHR pentapeptide repeat and GETHR pentapeptide repeat (5 copies). WB:WBGene00016902 C53D5.1 Predicted to be located in membrane. Is an ortholog of human DIPK1C (divergent protein kinase domain 1C). WB:WBGene00016903 marc-4 Predicted to enable MHC protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class II; immune response; and protein polyubiquitination. Predicted to be located in early endosome membrane; late endosome membrane; and lysosome. Is an ortholog of human MARCHF1 (membrane associated ring-CH-type finger 1). WB:WBGene00016905 ztf-3 Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Expressed in ASEL; ASER; neurons; pharynx; and rectum. WB:WBGene00016906 C53D5.5 Predicted to enable glutathione hydrolase activity. Predicted to be involved in glutathione catabolic process. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including biliary atresia; diabetes mellitus (multiple); and liver disease (multiple). Is an ortholog of human GGT1 (gamma-glutamyltransferase 1) and GGT2P (gamma-glutamyltransferase 2, pseudogene). WB:WBGene00016907 C53H9.2 Predicted to enable GTPase activity. Predicted to be involved in ribosomal subunit export from nucleus. Predicted to be located in cytosol. Is an ortholog of human LSG1 (large 60S subunit nuclear export GTPase 1). WB:WBGene00016909 frpr-4 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in PVM; muscle cell; and neurons. WB:WBGene00016911 drn-1 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in signal transduction. Predicted to be located in plasma membrane. Expressed in dorsal nerve cord; neurons; and tail ganglion. Is an ortholog of human DIRAS1 (DIRAS family GTPase 1). WB:WBGene00016912 clec-86 Predicted to enable carbohydrate binding activity. Involved in innate immune response. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; autoimmune disease (multiple); and cholangiocarcinoma. Is an ortholog of human REG1A (regenerating family member 1 alpha); REG1B (regenerating family member 1 beta); and REG3G (regenerating family member 3 gamma). WB:WBGene00016913 lam-2 Involved in positive regulation of locomotion. Predicted to be located in basement membrane. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; lung small cell carcinoma; and lung squamous cell carcinoma. Is an ortholog of human LAMC1 (laminin subunit gamma 1). WB:WBGene00016914 C54D1.7 Enriched in G2; W cell; hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00016915 idpp-11 Enriched in GABAergic neurons; arcade cell; hypodermis; and pharyngeal cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including Ethanol; methylmercury hydroxide; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: EB domain and EB module. WB:WBGene00016916 nlp-101 Enriched in head mesodermal cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and lin-4 based on RNA-seq and microarray studies. Is affected by 1-methylnicotinamide; D-glucose; and cholesterol based on RNA-seq studies. WB:WBGene00016917 C54E4.1 Enriched in lateral ganglion; neurons; and ventral nerve cord based on tiling array; single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including pgl-1; prg-1; and nhr-25 based on RNA-seq and microarray studies. Is affected by cholesterol; Chlorpyrifos; and Microcystin-LR based on RNA-seq and microarray studies. WB:WBGene00016918 test-1 Predicted to enable calcium ion binding activity. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human SPOCK1 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1); SPOCK2 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2); and SPOCK3 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3). WB:WBGene00016919 C54E4.4 Predicted to be located in membrane. WB:WBGene00016920 C54E4.5 Predicted to enable inositol oxygenase activity. Predicted to be involved in inositol catabolic process. Predicted to be located in cytoplasm. Is an ortholog of human MIOX (myo-inositol oxygenase). WB:WBGene00016921 C54F6.3 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00016922 swt-2 Predicted to enable sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport. Predicted to be located in Golgi membrane and plasma membrane. Is an ortholog of human SLC50A1 (solute carrier family 50 member 1). WB:WBGene00016923 C54F6.5 Enriched in SMB; body wall musculature; dopaminergic neurons; germ line; and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including hydrogen sulfide; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00016924 C54F6.6 Enriched in AMshL; AMshR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including tryptophan; multi-walled carbon nanotube; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00016925 srb-18 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00016926 nhr-171 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016927 nhr-172 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016928 srb-19 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00016929 C54F6.12 Enriched in dopaminergic neurons; hypodermis; and neuronal sheath cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00016930 madf-6 Predicted to enable DNA binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00016931 C54G6.2 Predicted to be involved in maintenance of Golgi location and maintenance of centrosome location. Predicted to be located in spindle pole centrosome. Is an ortholog of human TBCCD1 (TBCC domain containing 1). WB:WBGene00016932 C54G6.3 Predicted to be located in membrane. WB:WBGene00016933 C54G7.1 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including tryptophan; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00016934 mboa-3 Predicted to enable acyltransferase activity. Predicted to be involved in lipid modification. Predicted to be located in membrane. Is an ortholog of human MBOAT1 (membrane bound O-acyltransferase domain containing 1) and MBOAT2 (membrane bound O-acyltransferase domain containing 2). WB:WBGene00016935 ifta-1 Involved in chemotaxis; intraciliary transport; and non-motile cilium assembly. Located in axoneme and ciliary basal body. Expressed in amphid neurons; inner labial neurons; outer labial neurons; and phasmid neurons. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome; cranioectodermal dysplasia 2; and short-rib thoracic dysplasia 7 with or without polydactyly. Is an ortholog of human WDR35 (WD repeat domain 35). WB:WBGene00016936 C54H2.2 No description available WB:WBGene00016937 tag-294 Predicted to enable DNA binding activity and transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of human RYBP (RING1 and YY1 binding protein). WB:WBGene00016938 C54H2.4 Enriched in g1P and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00016939 C55B6.1 Predicted to enable kinase activity. Predicted to be involved in glycerol metabolic process; phosphate-containing compound metabolic process; and triglyceride metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human GK5 (glycerol kinase 5). WB:WBGene00016940 C55B6.4 Enriched in NSM; hypodermis; muscle cell; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-12; lin-4; and lin-14 based on microarray and tiling array studies. WB:WBGene00016941 C55B6.5 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00016942 C55B7.3 Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of human PTPN7 (protein tyrosine phosphatase non-receptor type 7). WB:WBGene00016943 acdh-1 Predicted to enable acyl-CoA dehydrogenase activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in mitochondrion. Expressed in E lineage cell; hypodermis; and neurons. Is an ortholog of human ACADSB (acyl-CoA dehydrogenase short/branched chain). WB:WBGene00016944 uri-1 Predicted to enable chromatin binding activity; phosphatase inhibitor activity; and transcription corepressor activity. Involved in several processes, including germ-line stem cell division; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and regulation of cell cycle. Expressed in germ line. Is an ortholog of human URI1 (URI1 prefoldin like chaperone). WB:WBGene00016945 sulp-1 Predicted to enable salt transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Predicted to be located in membrane. Expressed in body wall musculature; excretory cell; hypodermis; intestine; and neurons. Human ortholog(s) of this gene implicated in congenital secretory chloride diarrhea 1. Is an ortholog of human SLC26A3 (solute carrier family 26 member 3). WB:WBGene00016946 C55B7.10 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00016947 C55B7.11 Enriched in several structures, including ABalapppaa; ABalppppppa; germ line; head mesodermal cell; and lateral ganglion based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00016948 scrt-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00016949 C55C2.3 Predicted to be located in membrane. WB:WBGene00016950 C55C2.4 Predicted to be located in membrane. WB:WBGene00016951 C55C3.1 Predicted to enable lipid binding activity. Predicted to be located in extracellular space. Is an ortholog of human LBP (lipopolysaccharide binding protein). WB:WBGene00016953 C55C3.3 Predicted to be located in membrane. WB:WBGene00016954 C55C3.4 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00016955 perm-5 Predicted to enable lipid binding activity. Predicted to be located in extracellular region. Expressed in several structures, including P5.ppal; P5.ppar; P7.papl; P7.papr; and vulval cell. WB:WBGene00016956 C55C3.6 Predicted to be located in membrane. WB:WBGene00016957 atic-1 Predicted to enable IMP cyclohydrolase activity and phosphoribosylaminoimidazolecarboxamide formyltransferase activity. Predicted to be involved in 'de novo' IMP biosynthetic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in purine-pyrimidine metabolic disorder. Is an ortholog of human ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase). WB:WBGene00016958 ilys-4 Predicted to enable lysozyme activity. Predicted to be involved in defense response to bacterium and killing of cells of another organism. Expressed in DD neuron and neurons. WB:WBGene00016959 C55H1.1 Is affected by several genes including clk-1; hpl-2; and pry-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00016960 vps-33.2 Involved in spermatocyte division. Predicted to be located in lysosome. Predicted to be part of CORVET complex. Expressed in intestine; pharynx; and spermatheca. Used to study ARC syndrome. Human ortholog(s) of this gene implicated in several diseases, including arthrogryposis multiplex congenita; arthrogryposis, renal dysfunction, and cholestasis 1; and progressive familial intrahepatic cholestasis. Is an ortholog of human VPS33B (VPS33B late endosome and lysosome associated). WB:WBGene00016961 vps-32.1 Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and vesicle budding from membrane. Located in endosome membrane. Expressed in gonad; neurons; and vulva. Human ortholog(s) of this gene implicated in cataract 31 multiple types. Is an ortholog of human CHMP4B (charged multivesicular body protein 4B) and CHMP4BP1 (charged multivesicular body protein 4B pseudogene 1). WB:WBGene00016962 C56C10.4 Enriched in anterior hypodermis; interfacial epithelial cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00016963 C56C10.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00016964 C56C10.7 Predicted to be part of TRAPPIII protein complex. Is an ortholog of human TRAPPC13 (trafficking protein particle complex subunit 13). WB:WBGene00016965 C56C10.9 Predicted to enable calcium ion binding activity. Predicted to be involved in calcium-ion regulated exocytosis. Predicted to be located in endoplasmic reticulum. Is an ortholog of human SDF4 (stromal cell derived factor 4). WB:WBGene00016966 aipr-1 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Expressed in several structures, including amphid sheath cell; dorsal nerve cord; neurons; oocyte; and spermatheca. Human ortholog(s) of this gene implicated in eye disease (multiple) and pituitary adenoma 1. Is an ortholog of human AIP (aryl hydrocarbon receptor interacting protein). WB:WBGene00016968 epg-5 Involved in macroautophagy and negative regulation of autophagosome assembly. Located in cytoplasm. Expressed in several structures, including body wall musculature; head; intestine; pharyngeal muscle cell; and tail. Human ortholog(s) of this gene implicated in Vici syndrome. Is an ortholog of human EPG5 (ectopic P-granules 5 autophagy tethering factor). WB:WBGene00016970 C56E6.2 Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to be located in endomembrane system. WB:WBGene00016971 toe-2 Predicted to enable kinase activity. Involved in positive regulation of apoptotic process and regulation of asymmetric cell division. Predicted to be located in several cellular components, including intracellular non-membrane-bounded organelle; midbody; and nucleus. Expressed in several structures, including QL.aa; QL.pp; QR.aa; QR.pp; and oxygen sensory neurons. WB:WBGene00016972 C56E6.4 Predicted to be involved in intracellular signal transduction. WB:WBGene00016973 abch-1 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of ATP-binding activity cassette (ABC) transporter complex. Expressed in head. Human ortholog(s) of this gene implicated in arteriosclerosis and sitosterolemia. Is an ortholog of human ABCG5 (ATP binding cassette subfamily G member 5). WB:WBGene00016974 lron-15 Enriched in ADE sheath cell; head ganglion; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including 1-methylnicotinamide; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily; Leucine-rich repeat, typical subtype; Leucine rich repeat; and Leucine-rich repeat. WB:WBGene00016975 nhr-173 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00016976 C56E10.3 Enriched in amphid sheath cell; excretory cell; intestine; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; Zidovudine; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00016977 akap-1 Predicted to enable RNA binding activity. Predicted to be located in cytoplasm and membrane. Expressed in several structures, including gonad and neurons. Is an ortholog of human AKAP1 (A-kinase anchoring protein 1). WB:WBGene00016978 trmt-10C.2 Predicted to enable tRNA (guanine-N1-)-methyltransferase activity and tRNA binding activity. Predicted to be involved in mitochondrial tRNA 5'-end processing and positive regulation of mitochondrial translation. Predicted to be located in mitochondrion and nucleoplasm. WB:WBGene00016979 C56G2.4 Enriched in interfacial epithelial cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: PEBP-like superfamily. WB:WBGene00016980 C56G2.5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. WB:WBGene00016981 rpn-13 Enables ubiquitin-specific protease binding activity. Predicted to be involved in proteasome assembly. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome regulatory particle, lid subcomplex. Expressed in intestine; neurons; and seam cell. Is an ortholog of human ADRM1 (ADRM1 26S proteasome ubiquitin receptor). WB:WBGene00016982 C56G2.9 Enriched in neurons and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and nhr-49 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including stavudine; Sodium Chloride; and Rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00016983 C56G2.15 Predicted to enable N-acetyltransferase activity and acetyl-CoA binding activity. Predicted to be located in cytoplasm. Is an ortholog of human NAA80 (N-alpha-acetyltransferase 80, NatH catalytic subunit). WB:WBGene00016984 npr-8 Predicted to enable neuropeptide Y receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00016985 C56G3.2 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. WB:WBGene00016987 CC8.2 Predicted to enable glycogen binding activity and protein phosphatase 1 binding activity. Predicted to be involved in regulation of glycogen biosynthetic process. Predicted to be part of protein phosphatase type 1 complex. Is an ortholog of human PPP1R3D (protein phosphatase 1 regulatory subunit 3D). WB:WBGene00016988 CD4.1 Predicted to be located in membrane. WB:WBGene00016989 mrpl-48 Predicted to be located in mitochondrial ribosome. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human MRPL48 (mitochondrial ribosomal protein L48). WB:WBGene00016990 vps-37 Involved in receptor catabolic process. Located in cytosol and endosome membrane. Part of ESCRT I complex. Expressed in head and tail. Is an ortholog of human VPS37B (VPS37B subunit of ESCRT-I). WB:WBGene00016992 zhit-1 Predicted to enable nucleosome binding activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus. Predicted to be part of Swr1 complex. Is an ortholog of human ZNHIT1 (zinc finger HIT-type containing 1). WB:WBGene00016993 CD4.8 Enriched in several structures, including ABplppppaa; ABprppppaa; germ line; germline precursor cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; manganese chloride; and bisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00016995 acly-1 Predicted to enable ATP citrate synthase activity. Predicted to be involved in acetyl-CoA biosynthetic process and fatty acid biosynthetic process. Predicted to be located in cytosol. Is an ortholog of human ACLY (ATP citrate lyase). WB:WBGene00016996 D1005.2 Predicted to enable UTP:glucose-1-phosphate uridylyltransferase activity. Predicted to be involved in UDP-glucose metabolic process and glycogen metabolic process. Predicted to be located in cytoplasm. WB:WBGene00016997 cebp-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including axon regeneration; regulation of extent of cell growth; and regulation of presynapse assembly. Located in cytoplasm; nucleus; and synapse. Expressed in hypodermis; intestine; muscle cell; neurons; and pharynx. WB:WBGene00016998 D1005.4 Predicted to be located in membrane. WB:WBGene00016999 D1005.5 Is affected by several genes including nhr-49; lin-15B; and hpl-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; methylmercuric chloride; and Mercuric Chloride based on microarray and RNA-seq studies. WB:WBGene00017000 D1005.6 Enriched in neurons and ventral nerve cord based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; dpy-21; and hda-2 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; Psoralens; and Chlorpyrifos based on RNA-seq and microarray studies. WB:WBGene00017001 D1007.3 Predicted to be located in membrane. WB:WBGene00017002 D1007.4 Predicted to be involved in spliceosomal snRNP assembly. Located in striated muscle dense body. Is an ortholog of human GEMIN6 (gem nuclear organelle associated protein 6). WB:WBGene00017003 tmem-39 Predicted to be located in membrane. Expressed in hypodermis; intestine; and nervous system. Is an ortholog of human TMEM39A (transmembrane protein 39A) and TMEM39B (transmembrane protein 39B). WB:WBGene00017004 nrd-1 Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in mRNA 3'-end processing. Is an ortholog of human SCAF4 (SR-related CTD associated factor 4). WB:WBGene00017005 D1007.8 Predicted to enable single-stranded DNA binding activity and telomeric DNA binding activity. Predicted to be involved in DNA replication; double-strand break repair via homologous recombination; and nucleotide-excision repair. Predicted to be located in chromosome, telomeric region and site of double-strand break. Predicted to be part of DNA replication factor A complex. WB:WBGene00017007 D1007.10 Predicted to be located in membrane. WB:WBGene00017009 idpp-10 Enriched in anterior hypodermis; arcade cell; muscle cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00017010 D1007.15 Predicted to be located in membrane. Is an ortholog of human TMEM94 (transmembrane protein 94). WB:WBGene00017011 eaf-1 Predicted to enable transcription elongation factor activity. Predicted to be involved in transcription elongation by RNA polymerase II. Located in nucleus. Expressed in hypodermis; pharynx; tail; and vulva. Human ortholog(s) of this gene implicated in prostate cancer. Is an ortholog of human EAF1 (ELL associated factor 1) and EAF2 (ELL associated factor 2). WB:WBGene00017012 acs-22 Predicted to enable long-chain fatty acid transporter activity and long-chain fatty acid-CoA ligase activity. Predicted to be involved in triglyceride homeostasis. Located in endoplasmic reticulum. Expressed in head neurons; hypodermis; and pharynx. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human SLC27A1 (solute carrier family 27 member 1) and SLC27A4 (solute carrier family 27 member 4). WB:WBGene00017013 ensh-1 Predicted to be located in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in familial hypobetalipoproteinemia 2. Is an ortholog of human ANGPTL3 (angiopoietin like 3). WB:WBGene00017014 dylt-2 Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Located in axoneme. Expressed in inner labial neurons and outer labial neurons. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Is an ortholog of human DYNLT2B (dynein light chain Tctex-type 2B). WB:WBGene00017015 D1014.2 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00017016 snap-1 Predicted to enable soluble NSF attachment protein activity and syntaxin binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in membrane. Predicted to be part of SNARE complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; Down syndrome; and developmental and epileptic encephalopathy 107. Is an ortholog of human NAPA (NSF attachment protein alpha) and NAPB (NSF attachment protein beta). WB:WBGene00017017 D1014.4 Enriched in several structures, including ABaraappaa; ABplpapppa; germ line; rectal epithelial cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including rotenone; stavudine; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017018 D1014.5 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00017019 D1014.6 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00017020 D1014.7 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00017021 D1022.2 Enriched in PLM; body wall muscle cell; sensory neurons; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00017022 D1022.3 Predicted to enable hydrolase activity. WB:WBGene00017023 D1022.4 Predicted to enable hydrolase activity. WB:WBGene00017024 D1022.5 Predicted to enable hydrolase activity. WB:WBGene00017025 D1037.1 Predicted to enable RNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Human ortholog(s) of this gene implicated in congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay. Is an ortholog of human SON (SON DNA and RNA binding protein). WB:WBGene00017026 ipla-4 Predicted to enable hydrolase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00017027 D1044.1 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00017028 dex-1 Predicted to enable calcium ion binding activity. Involved in amphid sensory organ dendrite retrograde extension. Located in dendrite membrane. Expressed in several structures, including anterior deirid sensillum; excretory system; pharynx; rectum; and socket cell. WB:WBGene00017029 D1044.4 Is affected by several genes including daf-2; clk-1; and eri-1 based on tiling array and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00017031 D1044.6 Predicted to be involved in negative regulation of DNA-templated transcription and positive regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Is an ortholog of human ZNF318 (zinc finger protein 318). WB:WBGene00017032 D1044.7 Enriched in ABplapaaapa; ABprapaaapa; BDU; g1; and touch receptor neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including cholesterol; cadmium; and Colistin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: EB domain; EB module; Lustrin, cysteine-rich repeated; Cysteine-rich repeat; and Lustrin, cysteine-rich repeated domain. WB:WBGene00017033 nekl-4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in regulation of cell cycle G2/M phase transition. Predicted to be located in cellular anatomical entity. Expressed in PQR; amphid neurons; ciliated neurons; and phasmid neurons. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 44. Is an ortholog of human NEK10 (NIMA related kinase 10). WB:WBGene00017034 otpl-2 Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Expressed in neurons and pharynx. Is an ortholog of human OTOP1 (otopetrin 1). WB:WBGene00017035 D1065.3 Enriched in muscle cell and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00017036 D1069.1 Predicted to be located in plasma membrane. WB:WBGene00017037 D1069.3 Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 5. Is an ortholog of human HYCC1 (hyccin PI4KA lipid kinase complex subunit 1) and HYCC2 (hyccin PI4KA lipid kinase complex subunit 2). WB:WBGene00017038 dmsr-4 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00017039 trk-1 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. WB:WBGene00017040 D1079.1 Predicted to be located in membrane. WB:WBGene00017041 D2007.1 Involved in innate immune response. Expressed in body wall musculature; head neurons; pharyngeal muscle cell; and spermatheca. WB:WBGene00017042 D2007.2 Predicted to be located in cytoskeleton. Expressed in head; motor neurons; and ventral nerve cord. WB:WBGene00017044 mrpl-18 Predicted to enable 5S rRNA binding activity. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial large ribosomal subunit. Expressed in body wall musculature; neurons; and vulval muscle. Is an ortholog of human MRPL18 (mitochondrial ribosomal protein L18). WB:WBGene00017045 atg-13 Predicted to be involved in mitophagy; piecemeal microautophagy of the nucleus; and protein localization to phagophore assembly site. Predicted to be located in cytosol and phagophore assembly site. Predicted to be part of Atg1/ULK1 kinase complex. Expressed in body wall musculature; nerve ring; neurons; and pharyngeal muscle cell. Is an ortholog of human ATG13 (autophagy related 13). WB:WBGene00017046 utx-1 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; chromatin DNA binding activity; and histone H3K27me2/H3K27me3 demethylase activity. Involved in cell fate specification and programmed cell death. Part of MLL3/4 complex. Expressed in several structures, including germ line; gonad; intestine; pharynx; and tail. Human ortholog(s) of this gene implicated in several diseases, including Kabuki syndrome; breast cancer (multiple); and carcinoma (multiple). Is an ortholog of human KDM6A (lysine demethylase 6A) and UTY (ubiquitously transcribed tetratricopeptide repeat containing, Y-linked). WB:WBGene00017048 D2021.4 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid catabolic process. Predicted to be located in peroxisomal matrix. WB:WBGene00017050 D2024.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00017051 afmd-1 Predicted to be involved in tryptophan catabolic process to kynurenine. Predicted to be located in cytoplasm. Is an ortholog of human AFMID (arylformamidase). WB:WBGene00017052 D2024.4 Enriched in arc ant V; hyp1; hyp2; neurons; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; multi-walled carbon nanotube; and stavudine based on RNA-seq and microarray studies. WB:WBGene00017053 D2024.5 Located in endoplasmic reticulum. WB:WBGene00017054 gstk-2 Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Located in mitochondrion. Expressed in body wall musculature; intestine; and pharynx. Is an ortholog of human GSTK1 (glutathione S-transferase kappa 1). WB:WBGene00017055 D2062.1 Predicted to be located in extracellular space. WB:WBGene00017056 D2062.4 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. WB:WBGene00017057 D2062.5 Predicted to be located in membrane. WB:WBGene00017058 msrp-6 Enriched in GABAergic neurons; germ line; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00017059 msrp-5 Predicted to be located in membrane. WB:WBGene00017060 D2063.1 Predicted to enable alcohol dehydrogenase (NAD+) activity. Located in striated muscle dense body. WB:WBGene00017061 oac-12 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00017062 glrx-3 Predicted to enable iron-sulfur cluster binding activity and metal ion binding activity. Predicted to be involved in intracellular iron ion homeostasis. Located in striated muscle dense body. Is an ortholog of human GLRX3 (glutaredoxin 3). WB:WBGene00017063 mctp-1 Predicted to enable calcium ion binding activity. Predicted to be involved in regulation of neurotransmitter secretion. Predicted to be located in synaptic vesicle membrane. Expressed in ciliated neurons; spermatheca; and ventral cord neurons. Is an ortholog of human MCTP1 (multiple C2 and transmembrane domain containing 1) and MCTP2 (multiple C2 and transmembrane domain containing 2). WB:WBGene00017064 ppfr-2 Predicted to enable protein phosphatase regulator activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of protein phosphatase 4 complex. Is an ortholog of human PPP4R2 (protein phosphatase 4 regulatory subunit 2). WB:WBGene00017065 D2092.4 Located in myofibril. WB:WBGene00017066 maco-1 Predicted to enable microtubule binding activity. Involved in chemotaxis; neuronal signal transduction; and thermotaxis. Located in neuronal cell body; nuclear envelope; and rough endoplasmic reticulum. Expressed in epithelial cell; muscle cell; and nervous system. Is an ortholog of human MACO1 (macoilin 1). WB:WBGene00017068 D2092.8 Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. WB:WBGene00017069 timm-17B.2 Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. WB:WBGene00017070 praf-3 Predicted to be located in membrane. Is an ortholog of human ARL6IP5 (ADP ribosylation factor like GTPase 6 interacting protein 5) and PRAF2 (PRA1 domain family member 2). WB:WBGene00017071 aagr-1 Enables alpha-1,4-glucosidase activity. Involved in glycogen catabolic process. Predicted to be located in lysosome. Is an ortholog of human MGAM (maltase-glucoamylase). WB:WBGene00017072 D2096.5 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; germ line; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Transthyretin-like superfamily; Protein of unknown function DUF870, Caenorhabditis species; and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00017073 D2096.6 Involved in endoplasmic reticulum unfolded protein response. Expressed in epithelial cell; marginal cell; pharyngeal muscle cell; and pharynx. WB:WBGene00017074 D2096.7 Enriched in several structures, including ABalpapaap; ABalpapppa; ABalppppaa; ABarapappa; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; glp-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00017075 nap-1 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and cholesterol binding activity. Predicted to be involved in nucleosome assembly. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in appendiceal neoplasm; hepatoblastoma; and pancreatic cancer. Is an ortholog of human NAP1L1 (nucleosome assembly protein 1 like 1); NAP1L2 (nucleosome assembly protein 1 like 2); and NAP1L4 (nucleosome assembly protein 1 like 4). WB:WBGene00017076 D2096.9 Enriched in several structures, including XXX cell; neurons; pm8; retrovesicular ganglion; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; daf-12; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including methylmercury hydroxide; rotenone; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00017077 D2096.10 Enriched in several structures, including cephalic sheath cell; germ line; head mesodermal cell; hypodermis; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq; microarray; and tiling array studies. Is affected by nine chemicals including mianserin; sesamin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00017078 D2096.11 Predicted to enable microtubule binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to be located in microtubule organizing center. Predicted to be part of filamentous actin. WB:WBGene00017079 D2096.12 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00017080 lec-12 Predicted to enable galactoside binding activity. Predicted to be located in membrane. Is an ortholog of human LGALS4 (galectin 4). WB:WBGene00017082 DC2.5 Enriched in several structures, including ABplpppapa; ABprpppapa; anal sphincter muscle; rectal epithelial cell; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including TPEN; Alovudine; and stavudine based on RNA-seq; proteomic; and microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and short chain dehydrogenase. Is an ortholog of human WWOX (WW domain containing oxidoreductase). WB:WBGene00017083 kin-33 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CHEK1 (checkpoint kinase 1). WB:WBGene00017084 E01A2.1 Predicted to enable enzyme regulator activity. Predicted to be involved in glutathione biosynthetic process. Predicted to be part of glutamate-cysteine ligase complex. Human ortholog(s) of this gene implicated in myocardial infarction and vascular dementia. Is an ortholog of human GCLM (glutamate-cysteine ligase modifier subunit). WB:WBGene00017085 srrt-1 Predicted to be involved in primary miRNA processing. Predicted to be located in nuclear body. Is an ortholog of human SRRT (serrate, RNA effector molecule). WB:WBGene00017087 dph-6 Predicted to enable diphthine-ammonia ligase activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine. Is an ortholog of human DPH6 (diphthamine biosynthesis 6). WB:WBGene00017088 akir-1 Predicted to enable transcription coregulator activity. Involved in meiotic sister chromatid cohesion and protein import into nucleus. Located in nucleus. Expressed in hyp7 syncytium and tail neurons. Is an ortholog of human AKIRIN2 (akirin 2). WB:WBGene00017089 poml-2 Predicted to enable arylesterase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); eye disease (multiple); and hematologic cancer (multiple). Is an ortholog of human PON1 (paraoxonase 1). WB:WBGene00017090 E01A2.8 Enriched in several structures, including ABalaappppa; ABalapaaaa; ABalapaappa; ABalapappaa; and nerve ring neurons based on single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and csr-1 based on microarray and RNA-seq studies. WB:WBGene00017091 ttr-40 Predicted to be located in cell surface and extracellular region. WB:WBGene00017092 E02C12.6 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00017093 E02C12.8 Enriched in AFD and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including methylmercuric chloride; mianserin; and D-glucopyranose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterized oxidoreductase dhs-27 and Uncharacterised oxidoreductase Dhs-27. WB:WBGene00017094 E02C12.9 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00017095 E02C12.10 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00017096 E02C12.11 Enriched in several structures, including ABalpppappp; ABalppppapa; accessory cell; ciliated neurons; and command interneuron based on tiling array and single-cell RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and nhr-49 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterized oxidoreductase dhs-27; Uncharacterised oxidoreductase Dhs-27; and Protein kinase-like domain superfamily. WB:WBGene00017097 E02C12.12 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00017098 E02D9.1 Predicted to enable RNA binding activity. Expressed in head and tail. WB:WBGene00017099 E02H9.1 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Zidovudine; and allantoin based on RNA-seq studies. WB:WBGene00017100 E02H9.2 Enriched in BAG; OLL; PVD; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including eat-2; elt-2; and nhr-49 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; Sodium Chloride; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00017101 E02H9.3 Enriched in DA neuron; VA neuron; germline precursor cell; head mesodermal cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF272); Protein of unknown function DUF272; and Phosphorylation site. WB:WBGene00017102 E02H9.4 Enriched in AFD and intestine based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; Tunicamycin; and mianserin based on RNA-seq and microarray studies. WB:WBGene00017103 klo-2 Predicted to enable beta-glucosidase activity. Predicted to be involved in carbohydrate metabolic process. Expressed in hypodermis and intestine. Used to study kidney disease. Human ortholog(s) of this gene implicated in several diseases, including congenital lactase deficiency; end stage renal disease; and intracranial embolism. Is an ortholog of human GBA3 (glucosylceramidase beta 3 (gene/pseudogene)) and LCTL (lactase like). WB:WBGene00017104 E02H9.6 Predicted to be located in membrane. WB:WBGene00017105 E02H9.7 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00017106 E02H9.9 Enriched in AVA; AVE; dopaminergic neurons; and male-specific anatomical entity based on tiling array and microarray studies. Is affected by several genes including daf-12; rrf-3; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Transthyretin-like superfamily. WB:WBGene00017107 srt-12 Predicted to be located in membrane. Expressed in AWAL; AWAR; and in male. WB:WBGene00017108 cyp-43A1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00017109 clec-177 Is affected by rsr-2; rsd-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00017110 clec-176 Predicted to be located in membrane. WB:WBGene00017111 E03H12.4 Is affected by sir-2.1 and eat-2 based on microarray studies. Is affected by resveratrol and cadmium based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00017112 E03H12.5 Enriched in AVE; germ line; sensory neurons; sperm; and in male based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-six chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00017113 srz-24 Predicted to be located in membrane. Expressed in ADLL; ADLR; ASJL; and ASJR. WB:WBGene00017114 E03H12.7 Predicted to be located in membrane. WB:WBGene00017115 E03H12.9 Enriched in ALML; ALMR; BDUL; and BDUR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on tiling array and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00017116 fbxb-78 Enriched in several structures, including ABalaaaala; ABalaapaaa; DB neuron; neurons; and rect_D based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including 1-methylnicotinamide; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00017117 fbxb-80 Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; bisphenol S; and metformin based on RNA-seq and microarray studies. WB:WBGene00017118 E04A4.3 Enriched in germ line based on RNA-seq studies. Is affected by several genes including eat-2; mex-3; and mex-1 based on tiling array and RNA-seq studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017119 timm-17B.1 Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is an ortholog of human TIMM17A (translocase of inner mitochondrial membrane 17A). WB:WBGene00017120 tctn-1 Predicted to be involved in cilium assembly. Predicted to be located in ciliary transition zone. Human ortholog(s) of this gene implicated in Joubert syndrome 13; Joubert syndrome 18; and orofaciodigital syndrome IV. Is an ortholog of human TCTN1 (tectonic family member 1) and TCTN3 (tectonic family member 3). WB:WBGene00017121 cyc-2.1 Enables electron transfer activity. Involved in electron transport chain. Predicted to be located in mitochondrial intermembrane space. Expressed in body wall musculature; excretory cell; intestinal cell; nervous system; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; carcinoma (multiple); and thrombocytopenia. Is an ortholog of human CYCS (cytochrome c, somatic). WB:WBGene00017122 pcrg-1 Predicted to enable Hsp70 protein binding activity and Hsp90 protein binding activity. Expressed in ASE and OLQ. Is an ortholog of human PACRG (parkin coregulated). WB:WBGene00017123 maoc-1 Enables identical protein binding activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in peroxisomal membrane. Used to study obesity. Human ortholog(s) of this gene implicated in D-bifunctional protein deficiency; Perrault syndrome; and Stiff-Person syndrome. Is an ortholog of human HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4). WB:WBGene00017124 E04F6.4 Predicted to enable catalytic activity. Predicted to be located in membrane. Is an ortholog of human PLD5 (phospholipase D family member 5). WB:WBGene00017125 acdh-12 Predicted to enable fatty-acyl-CoA binding activity and very-long-chain-acyl-CoA dehydrogenase activity. Human ortholog(s) of this gene implicated in Alzheimer's disease and very long chain acyl-CoA dehydrogenase deficiency. Is an ortholog of human ACADVL (acyl-CoA dehydrogenase very long chain). WB:WBGene00017126 E04F6.6 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and OLQ based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; bisphenol A; and 4-bromodiphenyl ether based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017127 E04F6.8 Enriched in several structures, including coelomocyte; excretory cell; head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00017128 E04F6.9 Enriched in several structures, including ABplpppaaa; AFD; body wall muscle cell from MS lineage; cephalic sheath cell; and mechanosensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; nicotine; and Zidovudine based on RNA-seq; proteomic; and microarray studies. WB:WBGene00017129 E04F6.10 Predicted to be located in membrane. WB:WBGene00017131 E04F6.15 Enriched in intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and short chain dehydrogenase. Is an ortholog of human WWOX (WW domain containing oxidoreductase). WB:WBGene00017132 tofu-6 Predicted to enable RNA binding activity. Involved in several processes, including embryonic cleavage; mitotic sister chromatid separation; and nucleic acid metabolic process. Located in nucleus and perinuclear region of cytoplasm. Expressed in germ line. WB:WBGene00017133 EEED8.2 Predicted to enable lipid binding activity. Expressed in hypodermis and intestine. WB:WBGene00017134 EEED8.3 Enriched in germ line; germline precursor cell; head mesodermal cell; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by nineteen chemicals including Heme; methylmercury hydroxide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Calycin. WB:WBGene00017135 EEED8.4 Predicted to enable poly(A) binding activity. Predicted to be located in nucleus. WB:WBGene00017136 ccpp-6 Enables metallocarboxypeptidase activity. Involved in egg-laying behavior and proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human AGBL4 (AGBL carboxypeptidase 4). WB:WBGene00017137 pink-1 Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including autophagy of mitochondrion; axon extension involved in axon guidance; and positive regulation of protein ubiquitination. Located in mitochondrion. Expressed in hermaphrodite distal tip cell; intestine; neurons; pharynx; and vulva. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease 6. Is an ortholog of human PINK1 (PTEN induced kinase 1). WB:WBGene00017138 EEED8.10 Predicted to enable RNA binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Is an ortholog of human FBXL13 (F-box and leucine rich repeat protein 13). WB:WBGene00017139 clec-141 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and lin-4 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00017140 EEED8.12 Predicted to enable poly(A) binding activity. Predicted to be located in nucleus. WB:WBGene00017141 EEED8.13 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including manganese chloride; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017142 EEED8.14 Enriched in several structures, including ABarppaapp; ABarpppapp; ALN; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Calycin. WB:WBGene00017143 EEED8.15 Enriched in several structures, including ABalaaaala; ABalaaaarl; CAN; germ line; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and mianserin based on RNA-seq and microarray studies. WB:WBGene00017144 brap-2 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Ras protein signal transduction and protein ubiquitination. Predicted to be located in cytoplasm. Is an ortholog of human BRAP (BRCA1 associated protein). WB:WBGene00017146 EGAP1.1 Enriched in anterior ganglion (post) and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Cadmium Chloride; Sodium Chloride; and Rifampin based on RNA-seq studies. WB:WBGene00017147 EGAP2.1 Enriched in ABplpappaa based on single-cell RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including aldicarb; Zidovudine; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00017148 EGAP2.2 Enriched in several structures, including DVC; body wall muscle cell; head neurons; intestine; and rect_D based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00017149 EGAP4.1 Predicted to be located in extracellular region. WB:WBGene00017150 EGAP5.1 Predicted to be involved in neuropeptide signaling pathway. Expressed in nervous system. WB:WBGene00017151 EGAP9.3 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00017152 EGAP798.1 Is affected by several genes including daf-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Progesterone based on microarray studies. WB:WBGene00017153 E_BE45912.2 Predicted to be located in membrane. WB:WBGene00017154 ugt-57 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00017156 F01E11.3 Predicted to be located in membrane. WB:WBGene00017157 tyra-2 Predicted to enable G protein-coupled amine receptor activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in neurons. WB:WBGene00017158 hpo-10 Predicted to be located in nucleus. Expressed widely. Is an ortholog of human LENG8 (leukocyte receptor cluster member 8). WB:WBGene00017159 F01F1.2 Predicted to be located in mitochondrion. Expressed in body wall musculature; intestine; and pharyngeal muscle cell. Is an ortholog of human CMC1 (C-X9-C motif containing 1). WB:WBGene00017160 F01F1.3 Enriched in GABAergic neurons; germ line; head mesodermal cell; intestine; and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Armadillo-type fold. WB:WBGene00017161 rabn-5 Enables GTPase activating protein binding activity. Involved in molting cycle. Is an ortholog of human RABEP1 (rabaptin, RAB GTPase binding effector protein 1). WB:WBGene00017162 ddx-23 Predicted to enable RNA binding activity. Involved in several processes, including developmental process involved in reproduction; embryonic body morphogenesis; and pre-miRNA processing. Located in nucleus. Expressed in germ cell; gonad; hypodermal cell; neurons; and ventral nerve cord. Is an ortholog of human DDX23 (DEAD-box helicase 23). WB:WBGene00017163 dnpp-1 Enables identical protein binding activity. Predicted to be involved in proteolysis. Predicted to be located in cytosol. Expressed in body wall musculature; intestine; pharynx; and vulva. Is an ortholog of human DNPEP (aspartyl aminopeptidase). WB:WBGene00017164 eng-1 Predicted to enable hydrolase activity, hydrolyzing O-glycosyl compounds. Predicted to be located in cytosol. Expressed in pharyngeal cell. Is an ortholog of human ENGASE (endo-beta-N-acetylglucosaminidase). WB:WBGene00017165 F01F1.11 Predicted to be located in endoplasmic reticulum. WB:WBGene00017166 aldo-2 Predicted to enable fructose-bisphosphate aldolase activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Predicted to be located in cytosol. Predicted to be part of heterochromatin. Expressed in several structures, including hyp7 syncytium. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system. Is an ortholog of human ALDOC (aldolase, fructose-bisphosphate C). WB:WBGene00017168 F01F1.14 Predicted to be located in membrane. WB:WBGene00017169 F01F1.15 Predicted to be located in endoplasmic reticulum. Is an ortholog of human CNPY2 (canopy FGF signaling regulator 2). WB:WBGene00017170 F01G12.1 Is affected by several genes including daf-2; eat-2; and bar-1 based on tiling array; microarray; and RNA-seq studies. Is affected by allantoin; Sirolimus; and adsorbable organic bromine compound based on RNA-seq and microarray studies. WB:WBGene00017172 F02C9.1 Predicted to be located in membrane. WB:WBGene00017173 F02C9.2 Predicted to be located in membrane. WB:WBGene00017174 tat-6 Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Predicted to be involved in endocytosis; phospholipid translocation; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in endosome; plasma membrane; and trans-Golgi network. Expressed in anterior spermathecal-uterine core cell; gonad; head; and tail. Is an ortholog of human ATP9B (ATPase phospholipid transporting 9B (putative)). WB:WBGene00017175 irld-3 Predicted to be located in membrane. WB:WBGene00017176 nmur-3 Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to be located in membrane. WB:WBGene00017177 F02E8.4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00017178 atg-16.1 Involved in aggrephagy. Located in cytoplasm. Expressed in embryonic cell; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Is an ortholog of human ATG16L1 (autophagy related 16 like 1). WB:WBGene00017179 wht-4 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including gout; hematologic cancer (multiple); and toxic encephalopathy. Is an ortholog of human ABCG1 (ATP binding cassette subfamily G member 1); ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)); and ABCG4 (ATP binding cassette subfamily G member 4). WB:WBGene00017180 F02E11.2 Enriched in nerve ring neurons and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00017181 F02E11.3 Enriched in Z1.p; Z4.a; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including elt-2; sir-2.1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Sterile alpha motif/pointed domain superfamily. WB:WBGene00017182 F02E11.4 Is affected by several genes including rrf-3; hpl-2; and drh-3 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Smr domain and Smr domain superfamily. WB:WBGene00017183 scl-15 Predicted to be located in extracellular space. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00017184 ncam-1 Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in axon and plasma membrane. Expressed in several structures, including GLR; germ line; neurons; somatic nervous system; and spermatheca. Human ortholog(s) of this gene implicated in several diseases, including brain glioblastoma multiforme; carcinoma (multiple); and insulinoma. Is an ortholog of human NCAM1 (neural cell adhesion molecule 1) and NCAM2 (neural cell adhesion molecule 2). WB:WBGene00017185 F07B7.1 Is affected by several genes including eat-2; clk-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including allantoin; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00017186 F07B7.2 Enriched in germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including hydrogen sulfide; allantoin; and Psoralens based on microarray; RNA-seq; and proteomic studies. WB:WBGene00017187 F07B7.6 No description available WB:WBGene00017188 F07B7.7 Is affected by several genes including hpl-2; hda-1; and his-24 based on microarray and RNA-seq studies. Is affected by four chemicals including Atrazine; tetrabromobisphenol A; and Colistin based on microarray studies. WB:WBGene00017189 F07B7.8 Enriched in several structures, including ABalapaaaa; ABalappapa; ABalpapppa; ABarapappa; and MSaapapa based on single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including mianserin; multi-walled carbon nanotube; and Ag nanoparticles based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00017190 F07B7.12 Enriched in neurons; pm6; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and sek-1 based on microarray and RNA-seq studies. Is affected by antimycin and Oligosaccharides based on RNA-seq and microarray studies. Human MYCBP2 enables several functions, including guanyl-nucleotide exchange factor activity; small GTPase binding activity; and zinc ion binding activity. Is predicted to encode a protein with the following domains: PHR; Regulator of chromosome condensation (RCC1) repeat; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; PHR domain superfamily; Regulator of chromosome condensation, RCC1; and PHR domain. Is an ortholog of human MYCBP2 (MYC binding protein 2). WB:WBGene00017191 F07B7.13 Enriched in body wall musculature; pharynx; somatic nervous system; tail neurons; and vulval muscle based on Chronogram studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00017192 F07B7.14 Is affected by mir-34 and mex-3 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00017193 F07C3.2 Predicted to be located in membrane. WB:WBGene00017194 F07C3.3 Enriched in several structures, including ABplapaaaa; ABprapaaaa; mechanosensory neurons; pharyngeal gland cell; and tail hypodermis based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; mianserin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Alkaline-phosphatase-like, core domain superfamily; Protein of unknown function (DUF229); and Protein of unknown function DUF229. WB:WBGene00017195 glo-4 Predicted to enable ubiquitin protein ligase activity. Involved in negative regulation of axon extension. Located in axon and synapse. Expressed in body wall musculature; intestine; muscle cell; nervous system; and pharynx. Human ortholog(s) of this gene implicated in atherosclerosis. Is an ortholog of human SERGEF (secretion regulating guanine nucleotide exchange factor). WB:WBGene00017197 F07C3.9 Predicted to be located in membrane. WB:WBGene00017198 nhr-36 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in amphid neurons. WB:WBGene00017199 clec-45 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. WB:WBGene00017200 F07C4.6 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; antimycin; and sucrose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00017201 grsp-4 Enriched in hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including bisphenol S; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00017202 clec-46 Enriched in DA neuron; VA neuron; and body wall muscle cell based on tiling array studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including Heme; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00017203 F07C4.10 Enriched in ABprpapppa; SIA; and g1P based on single-cell RNA-seq studies. Is affected by several genes including lin-4; lin-14; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; Mercuric Chloride; and Ag nanoparticles based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00017204 F07C4.11 Enriched in ABprpapppa; MSaapaapa; MSpapaapa; pharynx; and touch receptor neurons based on microarray and single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; Tunicamycin; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00017205 cest-29 Enriched in several structures, including ABalpppppa; ABalppppppp; ABplaapapa; ABplpaaaaa; and amphid neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; stavudine; and paraquat based on microarray and RNA-seq studies. WB:WBGene00017206 F07C7.1 No description available WB:WBGene00017207 fbxb-6 Enriched in XXX cell; germ line; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00017208 fbxb-35 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalppappa; ABalpppappp; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00017209 F07E5.4 Enriched in ABplppaapa; ABprppaapa; and coelomocyte based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00017210 F07E5.5 Predicted to enable enzyme binding activity; nucleic acid binding activity; and zinc ion binding activity. Predicted to be located in nucleolus. Is an ortholog of human ZCCHC9 (zinc finger CCHC-type containing 9). WB:WBGene00017211 fbxb-36 Enriched in ALA; amphid neurons; germ line; neuronal sheath cell; and pharyngeal cell based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017212 F07E5.7 Enriched in PLM and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by four chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and glycine based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017213 F07E5.8 Predicted to be located in membrane. WB:WBGene00017214 F07E5.9 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Sodium Chloride; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00017215 F07F6.1 Predicted to enable nucleic acid binding activity. WB:WBGene00017216 F07F6.2 Predicted to be located in membrane. WB:WBGene00017217 F07F6.4 Predicted to enable GTPase activator activity and metal ion binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in Golgi membrane. Is an ortholog of human ARFGAP2 (ADP ribosylation factor GTPase activating protein 2). WB:WBGene00017218 dct-5 Involved in defense response to Gram-negative bacterium. Predicted to be located in membrane. WB:WBGene00017219 F07F6.7 Predicted to enable lipid binding activity. Predicted to be involved in lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular region. Is an ortholog of human APOL3 (apolipoprotein L3). WB:WBGene00017220 F07F6.8 Predicted to enable lipid binding activity. Predicted to be involved in lipid transport and lipoprotein metabolic process. Predicted to be located in extracellular region. Is an ortholog of human APOL3 (apolipoprotein L3). WB:WBGene00017221 dgn-3 Predicted to be located in membrane. Predicted to be part of dystrophin-associated glycoprotein complex. WB:WBGene00017222 F07G6.2 Enriched in muscle cell; neurons; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including age-1; prg-1; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00017223 F07G6.3 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; eri-1; and rrf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00017224 F07G6.5 Is affected by several genes including hpl-2; cyc-1; and spn-4 based on microarray; tiling array; and RNA-seq studies. Is affected by allantoin and Sirolimus based on microarray studies. WB:WBGene00017225 fbxa-52 Enriched in hypodermis; intestine; seam cell; and tail precursor cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including methylmercury hydroxide; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and Phosphorylation site. WB:WBGene00017226 fbxa-53 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00017227 F07G6.8 Enriched in several structures, including ABplpppaaa; NSM; rectal epithelial cell; rectal gland cell; and tail hypodermis based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; sir-2.1; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00017228 F07G11.1 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00017229 F07G11.2 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00017230 F07G11.3 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00017231 F07G11.4 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00017232 F07G11.7 Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies. Is affected by single-walled carbon nanotube and Sirolimus based on microarray studies. WB:WBGene00017233 lmd-4 Predicted to enable chitin binding activity and hydrolase activity, acting on glycosyl bonds. Predicted to be involved in carbohydrate metabolic process and rejection of self pollen. WB:WBGene00017235 F08B4.3 Enriched in OLL; PVD; and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00017236 nlp-60 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in ASEL; ASER; and nervous system. WB:WBGene00017237 pole-2 Predicted to enable DNA binding activity. Predicted to be involved in DNA-templated DNA replication and error-prone translesion synthesis. Predicted to be located in chromosome and nuclear lumen. Predicted to be part of epsilon DNA polymerase complex. Is an ortholog of human POLE2 (DNA polymerase epsilon 2, accessory subunit). WB:WBGene00017238 snrp-3 Predicted to enable pre-mRNA 5'-splice site binding activity. Predicted to be involved in mRNA 5'-splice site recognition. Predicted to be located in nucleus. Predicted to be part of U1 snRNP. Human ortholog(s) of this gene implicated in mixed connective tissue disease and systemic lupus erythematosus. Is an ortholog of human SNRPC (small nuclear ribonucleoprotein polypeptide C). WB:WBGene00017239 F08B6.1 Enriched in germ line; intestine; and seam cell based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including rotenone; silicon dioxide nanoparticle; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00017240 calu-2 Predicted to enable calcium ion binding activity. Predicted to be located in endoplasmic reticulum. Expressed in body wall musculature; neurons; and pharynx. Is an ortholog of human RCN2 (reticulocalbin 2). WB:WBGene00017241 pcyt-1 Enables choline-phosphate cytidylyltransferase activity. Involved in phosphatidylcholine biosynthetic process. Expressed in head. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia with cone-rod dystrophy. Is an ortholog of human PCYT1A (phosphate cytidylyltransferase 1A, choline) and PCYT1B (phosphate cytidylyltransferase 1B, choline). WB:WBGene00017243 F08C6.5 Predicted to be located in membrane. WB:WBGene00017244 apy-1 Enables GDP phosphatase activity and UDP phosphatase activity. Involved in several processes, including determination of adult lifespan; endoplasmic reticulum unfolded protein response; and ribonucleoside diphosphate catabolic process. Located in membrane. Expressed in hypodermis and pharynx. Human ortholog(s) of this gene implicated in Desbuquois dysplasia and multiple epiphyseal dysplasia 7. Is an ortholog of human CANT1 (calcium activated nucleotidase 1). WB:WBGene00017245 srpa-72 Predicted to enable 7S RNA binding activity. Predicted to contribute to ribosome binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in endoplasmic reticulum. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is an ortholog of human SRP72 (signal recognition particle 72). WB:WBGene00017246 F08D12.2 Enriched in pharyngeal gland cell; rectal epithelial cell; and rectum based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; rotenone; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CC domain. WB:WBGene00017247 F08D12.3 Enriched in ABalaaaala; ABalaapaaa; pharyngeal gland cell; and pharyngeal neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: CC domain. WB:WBGene00017248 F08D12.4 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalaappppa; ABalapaappa; and excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; csr-1; and set-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including methylmercuric chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00017249 fbxb-108 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00017250 F08D12.7 Expressed in several structures, including enteric muscle; hermaphrodite distal tip cell; neurons; ventral nerve cord; and vulval muscle. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00017251 fbxb-105 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including hydrogen sulfide; methylmercuric chloride; and Mercuric Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00017252 sdz-10 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; hyp3; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; rotenone; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00017253 sdz-9 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalaappppa; RID; and ciliated neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00017254 fbxb-111 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ciliated neurons; and excretory gland cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00017255 F08D12.12 Enriched in several structures, including arcade cell; body ganglion; cholinergic neurons; pharyngeal neurons; and pharyngeal-intestinal valve cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and sek-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube; Sodium Chloride; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017257 F08F1.3 Predicted to be located in membrane. WB:WBGene00017258 F08F1.4 Enriched in PVR; PVW; germ line; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; rotenone; and stavudine based on microarray and RNA-seq studies. WB:WBGene00017259 F08F1.9 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in mitotic cell cycle phase transition. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin A2-CDK2 complex. WB:WBGene00017260 F08F3.1 Enriched in enteric muscle; head mesodermal cell; neurons; retrovesicular ganglion; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; pgl-1; and alg-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017261 acl-6 Predicted to enable glycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in cellular lipid metabolic process and glycerol-3-phosphate metabolic process. Located in mitochondrion. Expressed in muscle cell. Is an ortholog of human GPAM (glycerol-3-phosphate acyltransferase, mitochondrial). WB:WBGene00017262 F08F3.4 Predicted to enable L-threonine 3-dehydrogenase activity. Involved in innate immune response. Is an ortholog of human TDH (L-threonine dehydrogenase (pseudogene)). WB:WBGene00017263 F08F3.6 Expressed in germ line. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00017264 F08F3.8 Predicted to be located in membrane. WB:WBGene00017265 snpc-1.3 Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be part of snRNA-activating protein complex. Expressed in gonad; metacorpus; nerve ring; and terminal bulb. Is an ortholog of human SNAPC1 (small nuclear RNA activating complex polypeptide 1). WB:WBGene00017266 F08F3.10 Predicted to be located in membrane. WB:WBGene00017267 numr-2 Located in nucleus. Expressed in intestine; sensory neurons; uterine muscle; and vulval muscle. WB:WBGene00017268 hmgr-1 Predicted to enable hydroxymethylglutaryl-CoA reductase (NADPH) activity. Predicted to be involved in isoprenoid biosynthetic process and sterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane and peroxisomal membrane. Expressed in excretory cell; intestine; non-striated muscle; spermatheca; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autosomal recessive limb-girdle muscular dystrophy; dementia; intermediate coronary syndrome; and type 2 diabetes mellitus. Is an ortholog of human HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). WB:WBGene00017269 eco-1 Predicted to enable peptide-lysine-N-acetyltransferase activity. Predicted to be involved in mitotic sister chromatid cohesion. Predicted to be located in nucleus. Predicted to be part of chromatin. Human ortholog(s) of this gene implicated in Roberts syndrome; lung adenocarcinoma; and rheumatoid arthritis. Is an ortholog of human ESCO2 (establishment of sister chromatid cohesion N-acetyltransferase 2). WB:WBGene00017270 numr-1 Expressed in egg-laying apparatus; intestine; neurons; and pharynx. Is predicted to encode a protein with the following domains: Uncharacterized Strongylid L4 protein; Uncharacterized strongylid L4 protein; and Phosphorylation site. WB:WBGene00017271 F08F8.6 Predicted to be located in membrane. WB:WBGene00017272 F08F8.7 Predicted to enable D-ribulose-phosphate 3-epimerase activity and metal ion binding activity. Predicted to be involved in pentose-phosphate shunt, non-oxidative branch. Predicted to be located in cytosol. Is an ortholog of human RPEL1 (ribulose-5-phosphate-3-epimerase like 1). WB:WBGene00017273 gos-28 Predicted to enable SNAP receptor activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and vesicle fusion. Predicted to be located in Golgi medial cisterna and Golgi membrane. Predicted to be part of SNARE complex. Expressed in intestine; seam cell; and vulva. Is an ortholog of human GOSR1 (golgi SNAP receptor complex member 1). WB:WBGene00017274 F08F8.9 Enriched in body wall muscle cell and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and aak-2 based on microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017275 F08F8.10 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABprpaaapa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00017277 F09C12.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in prostate cancer. Is an ortholog of human MAPK7 (mitogen-activated protein kinase 7). WB:WBGene00017278 srsy-1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00017279 F09C12.8 Enriched in NSM; germ line; sensory neurons; and in male based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Histidine phosphatase superfamily (branch 1); Histidine phosphatase superfamily; and Histidine phosphatase superfamily, clade-1. WB:WBGene00017280 usp-39 Predicted to enable cysteine-type deubiquitinase activity and zinc ion binding activity. Predicted to be located in nucleus. Expressed in tail. Is an ortholog of human USP39 (ubiquitin specific peptidase 39). WB:WBGene00017281 F09D12.2 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00017282 algn-2 Predicted to enable alpha-1,3-mannosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ii and congenital myasthenic syndrome 14. Is an ortholog of human ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase). WB:WBGene00017283 F09E5.3 Predicted to enable deoxyribose-phosphate aldolase activity. Predicted to be involved in carbohydrate catabolic process and deoxyribonucleotide catabolic process. Predicted to be located in cytoplasm. Is an ortholog of human DERA (deoxyribose-phosphate aldolase). WB:WBGene00017284 sec-6 Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Predicted to be part of exocyst. Expressed in intestine; muscle cell; and nervous system. Is an ortholog of human EXOC3 (exocyst complex component 3). WB:WBGene00017285 F09E5.7 Enriched in several structures, including ABalaapppp; ABalapaapp; ABalappppa; PLM; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including let-7; gld-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including mianserin; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00017286 F09E5.8 Predicted to enable pyridoxal phosphate binding activity. Human ortholog(s) of this gene implicated in early-onset vitamin B6-dependent epilepsy. Is an ortholog of human PLPBP (pyridoxal phosphate binding protein). WB:WBGene00017287 F09E5.9 Enriched in intestine and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; pgl-1; and glh-1 based on microarray and RNA-seq studies. Is affected by Rifampin and Diazinon based on RNA-seq and microarray studies. WB:WBGene00017288 F09E5.10 Enriched in AVK; germ line; intestine; and sensory neurons based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by Quercetin; Humic Substances; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. WB:WBGene00017289 F09E5.11 Predicted to be involved in vacuolar proton-transporting V-type ATPase complex assembly. Predicted to be located in endomembrane system. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIp. Is an ortholog of human TMEM199 (transmembrane protein 199). WB:WBGene00017290 F09E5.12 Enriched in neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; pgl-1; and alg-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017291 F09E5.14 Enriched in neurons and pm8 based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including rotenone; Sodium Chloride; and Psoralens based on RNA-seq studies. WB:WBGene00017292 F09E5.16 Predicted to be located in membrane. WB:WBGene00017293 bmy-1 Enables identical protein binding activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 20. Is an ortholog of human MESD (mesoderm development LRP chaperone). WB:WBGene00017294 F09E10.1 Enriched in ADEL; ADER; dopaminergic neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including rotenone; Tunicamycin; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00017295 F09E10.5 Enriched in intestine and neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; pgl-1; and csr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by four chemicals including metformin; Sirolimus; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017296 F09E10.6 Predicted to be located in membrane. Expressed in head. WB:WBGene00017297 F09E10.7 Enriched in neurons; somatic gonad precursor; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4440; Domain of unknown function (DUF4440); and NTF2-like domain superfamily. WB:WBGene00017298 toca-1 Involved in several processes, including negative regulation of protein localization to adherens junction; positive regulation of egg-laying behavior; and regulation of cellular component organization. Located in cell-cell junction; intracellular vesicle; and plasma membrane. Expressed in anchor cell and vulF. Human ortholog(s) of this gene implicated in Huntington's disease. Is an ortholog of human FNBP1 (formin binding protein 1); FNBP1L (formin binding protein 1 like); and TRIP10 (thyroid hormone receptor interactor 10). WB:WBGene00017299 molo-1 Located in neuromuscular junction. Part of acetylcholine-gated channel complex. Expressed in motor neurons; ventral nerve cord; and vulval muscle. WB:WBGene00017300 rpc-2 Predicted to enable several functions, including DNA-directed 5'-3' RNA polymerase activity; metal ion binding activity; and ribonucleoside binding activity. Predicted to contribute to RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase III. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease and hypomyelinating leukodystrophy 8. Is an ortholog of human POLR3B (RNA polymerase III subunit B). WB:WBGene00017301 hach-1 Predicted to enable 3-hydroxyisobutyryl-CoA hydrolase activity. Predicted to be involved in valine catabolic process. Predicted to be located in mitochondrion. Is an ortholog of human HIBCH (3-hydroxyisobutyryl-CoA hydrolase). WB:WBGene00017302 F09F7.5 Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of Rho protein signal transduction and regulation of cell shape. Predicted to be located in cytoskeleton and plasma membrane. Is an ortholog of human CDC42SE1 (CDC42 small effector 1) and CDC42SE2 (CDC42 small effector 2). WB:WBGene00017303 F09F7.6 Enriched in several structures, including ADE sheath cell; ASER; dopaminergic neurons; hypodermis; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-six chemicals including aldicarb; hydrogen sulfide; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00017304 nmad-1 Enables oxidative DNA demethylase activity. Involved in several processes, including meiotic chromosome condensation; positive regulation of double-strand break repair; and positive regulation of reproductive process. Predicted to be located in nucleus. Expressed in muscle cell. Is an ortholog of human ALKBH4 (alkB homolog 4, lysine demethylase). WB:WBGene00017305 nspb-12 Enriched in several structures, including ABplppppaa; ABprppppaa; mechanosensory neurons; pharyngeal-intestinal valve cell; and pharynx based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; D-glucose; and Neurotoxins based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00017306 F09F9.1 Predicted to be located in membrane. WB:WBGene00017307 F09F9.2 Enriched in several structures, including germline precursor cell; interfacial epithelial cell; mechanosensory neurons; rectum; and tail hypodermis based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-six chemicals including methylmercury hydroxide; 1-methylnicotinamide; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017308 F09F9.3 Predicted to be located in membrane. WB:WBGene00017309 gogo-1 Predicted to be located in cell periphery. WB:WBGene00017310 F09G2.1 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. WB:WBGene00017311 F09G2.2 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in regulation of primary metabolic process. Predicted to be located in nucleus. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Expressed in several structures, including body wall musculature; head; intestine; pharyngeal cell; and tail. Is an ortholog of human CNPPD1 (cyclin Pas1/PHO80 domain containing 1). WB:WBGene00017312 pitr-5 Predicted to enable inorganic phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Is an ortholog of human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2). WB:WBGene00017313 cpsf-2 Predicted to enable RNA binding activity. Predicted to be involved in mRNA 3'-end processing by stem-loop binding activity and cleavage and mRNA polyadenylation. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is an ortholog of human CPSF2 (cleavage and polyadenylation specific factor 2). WB:WBGene00017314 lgc-39 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00017315 ugt-36 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1); UGT3A2 (UDP glycosyltransferase family 3 member A2); and UGT8 (UDP glycosyltransferase 8). WB:WBGene00017316 F09G2.8 Predicted to enable N-acylphosphatidylethanolamine-specific phospholipase D activity and phospholipase D activity. Predicted to be involved in lipid catabolic process. Predicted to be located in membrane. Expressed in tail. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 46. Is an ortholog of human PLD3 (phospholipase D family member 3) and PLD4 (phospholipase D family member 4). WB:WBGene00017317 attf-2 Predicted to enable DNA binding activity. WB:WBGene00017319 mrps-9 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS9 (mitochondrial ribosomal protein S9). WB:WBGene00017320 F09G8.5 Predicted to be involved in cytoskeleton organization. Human ortholog(s) of this gene implicated in axial spondylometaphyseal dysplasia. Is an ortholog of human CFAP410 (cilia and flagella associated protein 410). WB:WBGene00017321 F09G8.7 Enriched in ABalappaap; germ line; head mesodermal cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; gld-1; and npr-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; rotenone; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00017322 clec-160 Predicted to enable carbohydrate binding activity. Predicted to be located in extracellular region. WB:WBGene00017323 mps-4 Enables potassium channel regulator activity. Involved in regulation of potassium ion transport. Expressed in enteric muscle; ganglia; and pharyngeal segment. WB:WBGene00017324 F10C1.1 Enriched in NSM based on tiling array studies. Is affected by rsr-2; smgl-1; and drh-3 based on tiling array; microarray; and RNA-seq studies. Is affected by dafa#1 and Sirolimus based on microarray studies. WB:WBGene00017325 F10C1.3 Enriched in germ line; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00017326 dmd-5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in male anatomical structure morphogenesis and negative regulation of synapse pruning. Predicted to be located in nucleus. Expressed in AVG; ventral nerve cord; and in male. Is an ortholog of human DMRTA2 (DMRT like family A2) and DMRTB1 (DMRT like family B with proline rich C-terminal 1). WB:WBGene00017327 F10C1.8 Enriched in body wall musculature and head mesodermal cell based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including methylmercury hydroxide; nicotine; and Zidovudine based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Lamin tail domain superfamily; Lamin Tail Domain; Lamin tail domain; and Phosphorylation site. WB:WBGene00017328 nemp-1 Predicted to be located in nuclear envelope. Expressed in several structures, including arcade cell; pharyngeal cell; pharyngeal-intestinal valve; rectal gland cell; and spermatheca. Is an ortholog of human NEMP1 (nuclear envelope integral membrane protein 1) and NEMP2 (nuclear envelope integral membrane protein 2). WB:WBGene00017329 ugt-39 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00017330 sre-10 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00017331 ugt-40 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B15 (UDP glucuronosyltransferase family 2 member B15); and UGT2B17 (UDP glucuronosyltransferase family 2 member B17). WB:WBGene00017332 ugt-37 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT8 (UDP glycosyltransferase 8). WB:WBGene00017333 ugt-38 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00017334 F10D2.8 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00017335 F10D2.10 Predicted to enable hydrolase activity. WB:WBGene00017336 ugt-41 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00017338 npr-36 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00017339 mfsd-10 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in brush border membrane. Expressed in head. Is an ortholog of human MFSD10 (major facilitator superfamily domain containing 10). WB:WBGene00017340 F10D7.3 Predicted to enable glutathione disulfide oxidoreductase activity. Predicted to be involved in cellular response to oxidative stress. Predicted to be located in cytoplasm. WB:WBGene00017341 F10D7.4 Enriched in arcade cell; neurons; and pharyngeal-intestinal valve cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; age-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00017342 F10D7.5 Predicted to enable ubiquitin protein ligase activity. Is an ortholog of human NEURL1 (neuralized E3 ubiquitin protein ligase 1) and NEURL1B (neuralized E3 ubiquitin protein ligase 1B). WB:WBGene00017343 F10E7.1 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. WB:WBGene00017344 F10E7.2 Predicted to be located in membrane. WB:WBGene00017345 F10E7.3 Is affected by several genes including hsf-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by fluvastatin; dafa#1; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017347 F10E7.5 Predicted to be involved in nuclear-transcribed mRNA catabolic process; rRNA processing; and ribosomal large subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human MRTO4 (MRT4 homolog, ribosome maturation factor). WB:WBGene00017348 F10E7.6 Predicted to be located in membrane. WB:WBGene00017349 farl-11 Involved in endoplasmic reticulum organization; epithelial tube morphogenesis; and positive regulation of endocytic recycling. Located in endoplasmic reticulum. Expressed in germ line. Is an ortholog of human STRIP1 (striatin interacting protein 1) and STRIP2 (striatin interacting protein 2). WB:WBGene00017350 F10E7.9 Predicted to enable potassium:chloride symporter activity. Predicted to be involved in cell volume homeostasis; inorganic ion homeostasis; and monoatomic ion transmembrane transport. Predicted to be located in membrane. Expressed in nerve ring; retrovesicular ganglion neurons; and tail neurons. Is an ortholog of human SLC12A8 (solute carrier family 12 member 8). WB:WBGene00017351 cutl-5 Predicted to be located in membrane. WB:WBGene00017352 F10E7.11 Predicted to enable histone deacetylase binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Is an ortholog of human MIER1 (MIER1 transcriptional regulator); MIER2 (MIER family member 2); and MIER3 (MIER family member 3). WB:WBGene00017353 F10E9.1 Expressed in amphid neurons and phasmid neurons. WB:WBGene00017354 F10E9.2 Enriched in RID; amphid sheath cell; germ line; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including rotenone; manganese chloride; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017355 F10E9.3 Enriched in several structures, including ABalpppappp; ABpraaaappp; body wall muscle cell; germ line; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and gld-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterized protein F10E9.3-like and Phosphorylation site. WB:WBGene00017356 F10E9.4 Predicted to enable single-stranded DNA binding activity; single-stranded RNA binding activity; and translation initiation factor binding activity. Predicted to be involved in regulation of gene expression and transcription initiation at RNA polymerase II promoter. Predicted to be located in P-body. Predicted to be part of RNA polymerase II, core complex. WB:WBGene00017357 F10E9.5 Predicted to be involved in spliceosomal snRNP assembly. Predicted to be part of SMN complex. Is an ortholog of human GEMIN8 (gem nuclear organelle associated protein 8). WB:WBGene00017358 F10E9.7 Predicted to enable catalytic activity. WB:WBGene00017359 F10E9.10 Predicted to be located in membrane. WB:WBGene00017360 F10E9.11 Expressed in intestine. Human CCDC59 enables RNA binding activity. Is predicted to encode a protein with the following domains: Fyv7/TAP26; rRNA processing; and Phosphorylation site. Is an ortholog of human CCDC59 (coiled-coil domain containing 59). WB:WBGene00017361 F10E9.12 Enriched in excretory cell; head mesodermal cell; intestine; neuronal sheath cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-eight chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00017362 F10G2.1 Predicted to be located in membrane. Expressed in coelomocyte. WB:WBGene00017363 F10G2.2 Enriched in body wall muscle cell and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; glp-1; and daf-12 based on RNA-seq; microarray; and proteomic studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017364 clec-7 Involved in defense response to Gram-positive bacterium. WB:WBGene00017365 F10G2.4 Enriched in several structures, including AVE; B cell; dopaminergic neurons; germ line; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; Tunicamycin; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00017366 F10G2.7 Enriched in coelomocyte; germ line; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; Domain of unknown function DUF1248; and Protein of unknown function (DUF1248). WB:WBGene00017367 nhr-263 Predicted to be located in nucleus. WB:WBGene00017369 F10G7.5 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00017370 F10G7.6 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; npr-1; and hsp-6 based on RNA-seq; tiling array; and microarray studies. Is affected by nine chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00017371 sre-39 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00017372 F10G7.9 Predicted to enable metal ion binding activity. WB:WBGene00017373 F10G7.10 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process via the N-end rule pathway. Predicted to be located in cytoplasm. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human UBR3 (ubiquitin protein ligase E3 component n-recognin 3). WB:WBGene00017374 ttr-41 Predicted to be located in cell surface and extracellular region. WB:WBGene00017375 pbo-6 Enables extracellular ligand-gated monoatomic ion channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in body wall musculature. WB:WBGene00017376 F11C7.2 Expressed in amphid sheath cell and phasmid sheath cell. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; Thrombospondin type 1 domain; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00017378 F11C7.6 Enriched in several structures, including ABplapapppp; ABprapapppp; LUA; amphid sheath cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; pmk-1; and nhr-49 based on microarray; RNA-seq; and tiling array studies. Is affected by ten chemicals including Tunicamycin; Sodium Chloride; and allantoin based on microarray and RNA-seq studies. WB:WBGene00017379 F11C7.7 Enriched in K cell; K' cell; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including nhr-49; aak-2; and daf-18 based on microarray and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; rotenone; and antimycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; Thrombospondin type 1 domain; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00017380 F11D5.1 Enriched in several structures, including amphid sheath cell; head mesodermal cell; pharynx; rectal epithelial cell; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including rotenone; Zidovudine; and Oligosaccharides based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017381 ddr-2 Enables protein tyrosine kinase activity. Involved in interneuron axon guidance; motor neuron axon guidance; and positive regulation of axon regeneration. Located in axon and plasma membrane. Expressed in DD neuron; SAB; hypodermis; rectal gland cell; and tail. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); carcinoma (multiple); and gastrointestinal system cancer (multiple). Is an ortholog of human DDR1 (discoidin domain receptor tyrosine kinase 1). WB:WBGene00017382 F11D5.5 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00017383 F11D5.6 Enriched in DA neuron; VA neuron; body wall muscle cell; and hypodermis based on tiling array studies. Is affected by several genes including daf-2; smg-2; and lpd-3 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00017384 F11G11.4 Predicted to be located in membrane. WB:WBGene00017385 F11G11.5 Predicted to be located in lysosome; membrane; and perinuclear region of cytoplasm. Is an ortholog of human BRI3 (brain protein I3). WB:WBGene00017386 nspd-5 Enriched in several structures, including AVK; amphid sheath cell; germ line; intestine; and sperm based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-seven chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Caenorhabditis elegans protein of unknown function (DUF780) and Protein of unknown function DUF780, Caenorhabditis species. WB:WBGene00017387 mpst-4 Predicted to enable thiosulfate sulfurtransferase activity. Predicted to be located in mitochondrion. WB:WBGene00017388 F11G11.13 Predicted to enable ATP binding activity; arginine kinase activity; and creatine kinase activity. Predicted to be involved in phosphocreatine biosynthetic process and phosphorylation. WB:WBGene00017389 lgc-38 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in AIYL; AIYR; head; and tail. WB:WBGene00017390 F12A10.1 Predicted to be located in membrane. WB:WBGene00017391 F12A10.2 Enriched in OLL; PVD; intestine; and in male based on microarray and RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by six chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017392 basl-2 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including methylmercuric chloride; manganese chloride; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00017393 nep-5 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00017394 cal-8 Predicted to enable calcium ion binding activity and enzyme regulator activity. WB:WBGene00017395 F12A10.6 Enriched in ASER based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and mex-1 based on microarray and RNA-seq studies. WB:WBGene00017396 suex-1 Enriched in GABAergic neurons; MSpaaapa; dopaminergic neurons; excretory cell; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00017397 F12A10.8 Enriched in Psub1; germ line; germline precursor cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including hsf-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00017398 slc-17.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be located in membrane. WB:WBGene00017399 lgc-51 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in SMDDL; SMDDR; SMDVL; and SMDVR. WB:WBGene00017400 stg-2 Predicted to enable channel regulator activity and voltage-gated calcium channel activity. Involved in adult locomotory behavior and positive regulation of glutamatergic synaptic transmission. Predicted to be located in postsynaptic density membrane. Predicted to be part of AMPA glutamate receptor complex. WB:WBGene00017401 F12D9.2 Predicted to enable peptidase activity. Predicted to be involved in proteolysis. WB:WBGene00017402 F12E12.1 Enriched in several structures, including ABplapaaaap; RIH; carbon dioxide sensory neurons; germ line; and rect_D based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including Ethanol; rotenone; and sodium arsenite based on RNA-seq and microarray studies. WB:WBGene00017403 F12E12.2 Is affected by several genes including hpl-2; drh-3; and rsr-2 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00017404 F12E12.3 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including iron oxide nanoparticle; cholesterol; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00017405 bath-31 Enriched in ABplpppppp; ABprpppppp; AVDL; AVDR; and RID based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00017406 sdz-12 Predicted to enable metal ion binding activity. Expressed in several structures, including Z4.ap; dorsal uterine precursor; head muscle; head neurons; and ventral uterine precursor. Is an ortholog of human ZNF501 (zinc finger protein 501). WB:WBGene00017407 F12E12.6 Enriched in Z1.p; Z4.a; body wall muscle cell; male distal tip cell; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including rotenone; stavudine; and cholesterol based on RNA-seq studies. WB:WBGene00017408 sdz-11 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalaapppp; ABaraapapaa; and ABaraapppaa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; methylmercuric chloride; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00017410 F13A2.1 Enriched in several structures, including ABalapaaaa; ASI; male distal tip cell; mc1; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and mex-1 based on tiling array and RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00017411 F13A2.2 Enriched in several structures, including Z1.p; male distal tip cell; neurons; retrovesicular ganglion; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; elt-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; metformin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00017412 F13A2.3 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eri-1; mex-3; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00017413 F13A2.4 Expressed in intestine; pharynx; and tail neurons. WB:WBGene00017414 F13A2.5 Enriched in Z1.p; Z4.a; male distal tip cell; somatic gonad precursor; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; mex-3; and mex-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Cholestanol; Atrazine; and dafa#1 based on microarray studies. WB:WBGene00017415 F13A2.6 Is affected by several genes including sir-2.1; clk-1; and isp-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercury hydroxide; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00017416 F13B6.1 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalaapppa; ABalapaapa; and arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; D-glucose; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00017417 F13B6.2 Enriched in head mesodermal cell; intestine; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017418 F13B6.3 Enriched in several structures, including arcade cell; head mesodermal cell; pharyngeal-intestinal valve cell; rectal gland cell; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including rotenone; Alovudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00017419 sec-16A.2 Predicted to be involved in Golgi organization and protein localization to endoplasmic reticulum exit site. Predicted to be located in ER to Golgi transport vesicle membrane and endoplasmic reticulum exit site. Is an ortholog of human SEC16A (SEC16 homolog A, endoplasmic reticulum export factor). WB:WBGene00017420 F13B9.2 Enriched in hypodermis; rectal epithelial cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including methylmercury hydroxide; D-glucose; and sesamin based on RNA-seq and microarray studies. WB:WBGene00017421 cutl-29 Predicted to be located in membrane. WB:WBGene00017422 F13C5.1 Enriched in head mesodermal cell; neurons; and retrovesicular ganglion based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including methylmercuric chloride; 4-bromodiphenyl ether; and stavudine based on microarray and RNA-seq studies. WB:WBGene00017423 F13C5.2 Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in chromatin remodeling and regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed widely. WB:WBGene00017424 F13C5.3 Enriched in ABplppppaa; ABprppppaa; AMsoL; AMsoR; and dopaminergic neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including multi-walled carbon nanotube; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00017426 F13C5.5 Predicted to be located in membrane. WB:WBGene00017427 acp-5 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in membrane. WB:WBGene00017428 F13D11.3 Predicted to enable protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00017429 F13D11.4 Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in steroid biosynthetic process. WB:WBGene00017430 bcl-11 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head; hypodermis; muscle cell; neurons; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including beta thalassemia; immunodeficiency 49; and sickle cell anemia. Is an ortholog of human BCL11A (BCL11 transcription factor A) and BCL11B (BCL11 transcription factor B). WB:WBGene00017431 cest-33 Predicted to enable carboxylesterase activity. Predicted to be located in cytoplasm and plasma membrane. WB:WBGene00017432 F13H6.4 Is affected by several genes including eat-2; npr-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; Tunicamycin; and 4-bromodiphenyl ether based on microarray and RNA-seq studies. WB:WBGene00017433 F13H6.5 Predicted to be located in membrane. WB:WBGene00017434 F13H8.1 Enriched in several structures, including AVH; coelomocyte; head mesodermal cell; mechanosensory neurons; and pharyngeal muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; tiling array; and microarray studies. Is affected by ten chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017435 F13H8.2 Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in nucleolus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Expressed widely. Human ortholog(s) of this gene implicated in thyroid gland papillary carcinoma. Is an ortholog of human WDR3 (WD repeat domain 3). WB:WBGene00017436 F13H8.3 Predicted to enable hydrolase activity, hydrolyzing N-glycosyl compounds. Predicted to be involved in nucleobase-containing compound metabolic process and organonitrogen compound metabolic process. WB:WBGene00017437 nmgp-1 Predicted to be involved in neuron projection development. Predicted to be located in plasma membrane. Expressed in several structures, including cephalic sheath cell; neurons; somatic nervous system; tail ganglion; and ventral ganglion. Used to study depressive disorder. Human ortholog(s) of this gene implicated in Pelizaeus-Merzbacher disease and hereditary spastic paraplegia 2. Is an ortholog of human GPM6A (glycoprotein M6A); GPM6B (glycoprotein M6B); and PLP1 (proteolipid protein 1). WB:WBGene00017438 F13H8.5 Enriched in ADE sheath cell; germline precursor cell; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-four chemicals including hydrogen sulfide; Ethanol; and 1-methylnicotinamide based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00017439 F13H8.6 Enriched in muscle cell and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; sir-2.1; and hsp-6 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Protein-tyrosine phosphatase-like. WB:WBGene00017440 upb-1 Enables beta-ureidopropionase activity. Involved in beta-alanine biosynthetic process via 3-ureidopropionate; thymine catabolic process; and uracil catabolic process. Located in striated muscle dense body. Expressed in body wall musculature. Is an ortholog of human UPB1 (beta-ureidopropionase 1). WB:WBGene00017441 F13H8.8 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalppappa; AFD; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eleven chemicals including manganese chloride; Rifampin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017442 scly-1 Predicted to enable transaminase activity. Is an ortholog of human SCLY (selenocysteine lyase). WB:WBGene00017443 F13H8.11 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Predicted to be located in membrane. Is an ortholog of human PLB1 (phospholipase B1). WB:WBGene00017444 F13H8.12 Enriched in germ line; intestine; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including methylmercuric chloride; manganese chloride; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Immunoglobulin-like fold and PapD-like superfamily. WB:WBGene00017445 sid-5 Involved in RNA transport and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in late endosome. Expressed in embryonic cell; somatic cell; somatic gonad; and spermatheca. WB:WBGene00017446 F14B8.4 Enriched in hypodermis and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including rotenone; manganese chloride; and mianserin based on RNA-seq and microarray studies. WB:WBGene00017447 F14B8.5 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. WB:WBGene00017448 F14B8.6 Predicted to be located in membrane. WB:WBGene00017449 otpl-3 Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP2 (otopetrin 2). WB:WBGene00017450 bath-27 Enriched in PVPL; PVPR; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including glp-1; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including metformin; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00017451 lido-14 Predicted to be located in nucleus. WB:WBGene00017452 bath-29 Enriched in AFD; germ line; germline precursor cell; and head mesodermal cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; manganese chloride; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00017453 F14D2.5 Enriched in I5 neuron; cholinergic neurons; germ line; and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including fbf-1; mex-1; and sma-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00017454 irld-5 Enriched in AUAL; AUAR; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00017455 F14D2.7 Enriched in germ line; neurons; and in male based on proteomic; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including nicotinic acid; rotenone; and Zidovudine based on RNA-seq studies. WB:WBGene00017456 F14D2.8 Enriched in germ line; germline precursor cell; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and elt-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: F-box protein she-1-like. WB:WBGene00017457 F14D2.9 No description available WB:WBGene00017459 F14D2.11 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. WB:WBGene00017460 bath-30 Enriched in germ line; germline precursor cell; head mesodermal cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and gld-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including manganese chloride; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; TRAF-like; and Phosphorylation site. WB:WBGene00017461 bath-28 Enriched in PVT; germ line; germline precursor cell; head mesodermal cell; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including manganese chloride; Zidovudine; and bisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00017462 F14D2.14 Enriched in AFD; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and elt-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; Tunicamycin; and stavudine based on microarray and RNA-seq studies. WB:WBGene00017463 F14D12.1 Predicted to enable protein kinase binding activity. Predicted to be involved in neuromuscular junction development. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 10 and fetal akinesia deformation sequence syndrome 3. Is an ortholog of human DOK7 (docking protein 7). WB:WBGene00017464 sulp-2 Enables sulfate transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Located in basolateral plasma membrane and non-motile cilium. Expressed in dopaminergic neurons and intestine. Human ortholog(s) of this gene implicated in several diseases, including Pendred Syndrome; autosomal recessive nonsyndromic deafness (multiple); and calcium oxalate nephrolithiasis. Is an ortholog of several human genes including SLC26A1 (solute carrier family 26 member 1); SLC26A3 (solute carrier family 26 member 3); and SLC26A4 (solute carrier family 26 member 4). WB:WBGene00017465 F14F9.2 Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including sodium arsenite; nanoparticle; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00017466 F14F9.3 Predicted to enable zinc ion binding activity. WB:WBGene00017467 F14F9.4 Enriched in several structures, including ALA; VB neuron; Y cell; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-six chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray; RNA-seq; and proteomic studies. WB:WBGene00017468 F14F9.5 Predicted to enable catalytic activity. Predicted to be located in extracellular region. WB:WBGene00017469 F14F9.6 Enriched in AVL based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Tunicamycin; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00017470 F14H12.2 Is affected by several genes including daf-2; let-60; and hsf-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and Psoralens based on RNA-seq studies. WB:WBGene00017471 F14H12.3 Enriched in several structures, including ABplpaaaap; FLP; VC neuron; amphid socket cell; and arc ant V based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including methylmercuric chloride; Mercuric Chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; Thrombospondin type 1 domain; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00017472 cst-1 Predicted to enable protein serine/threonine kinase activity. Involved in determination of adult lifespan and muscle cell development. Predicted to be located in cytoplasm. Expressed in hypodermis; sensory neurons; terminal bulb; and vulva. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human STK3 (serine/threonine kinase 3). WB:WBGene00017473 F14H12.6 Predicted to be located in membrane. WB:WBGene00017474 F14H12.7 Predicted to be located in membrane. WB:WBGene00017475 F14H12.8 Predicted to be located in membrane. WB:WBGene00017476 F15A8.1 Predicted to be located in membrane. WB:WBGene00017478 cest-26 Predicted to enable carboxylic ester hydrolase activity. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). WB:WBGene00017480 nstp-2 Predicted to enable UDP-N-acetylglucosamine transmembrane transporter activity and UDP-xylose transmembrane transporter activity. Predicted to be involved in UDP-N-acetylglucosamine transmembrane transport and UDP-xylose transmembrane transport. Predicted to be located in endomembrane system and membrane. Is an ortholog of human SLC35B4 (solute carrier family 35 member B4). WB:WBGene00017481 F15B10.3 Enriched in germ line; muscle cell; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including methylmercuric chloride; Alovudine; and metformin based on microarray and RNA-seq studies. WB:WBGene00017482 set-9 Predicted to enable histone methyltransferase activity and metal ion binding activity. Involved in determination of adult lifespan. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant intellectual developmental disorder 23; esophagus squamous cell carcinoma; and prostate cancer. Is an ortholog of human SETD5 (SET domain containing 5). WB:WBGene00017483 lgc-22 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00017484 F15E6.3 Enriched in hypodermis and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-seven chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00017485 F15E6.4 Enriched in ASER; PLM; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00017486 F15E6.5 Enriched in AUAL; AUAR; arcade cell; and posterior arcade cell based on single-cell RNA-seq studies. Is affected by several genes including clk-1; lin-15B; and ubc-9 based on microarray and RNA-seq studies. Is affected by Tunicamycin; Sirolimus; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00017487 F15E6.6 Predicted to enable oxidoreductase activity. WB:WBGene00017488 dct-7 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00017489 F15E6.9 Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. WB:WBGene00017490 pud-2.1 Expressed in hypodermis and intestine. Is predicted to encode a protein with the following domains: Up-regulated in Daf-2 and Up-Regulated in long-lived daf-2. WB:WBGene00017491 irld-28 Enriched in body wall muscle cell and neurons based on tiling array and RNA-seq studies. Is affected by several genes including sir-2.1; mrps-5; and etr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by cadmium and fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00017492 irld-29 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by allantoin and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00017493 irld-30 Enriched in ADLL; ADLR; and neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including let-60; eat-2; and nhr-49 based on RNA-seq and microarray studies. Is affected by seven chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00017494 irld-31 Is affected by several genes including drh-3; qui-1; and adr-1 based on RNA-seq studies. Is affected by dibromoacetic acid and Sirolimus based on microarray studies. WB:WBGene00017496 srbc-15 Enriched in NSM based on tiling array studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00017497 irld-32 Is affected by several genes including let-60; sir-2.1; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Tunicamycin; resveratrol; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00017498 pud-4 Expressed in hyp7 syncytium. Is predicted to encode a protein with the following domains: Up-regulated in Daf-2 and Up-Regulated in long-lived daf-2. WB:WBGene00017499 pud-1.1 Expressed in hypodermis and intestine. Is predicted to encode a protein with the following domains: Up-regulated in Daf-2 and Up-Regulated in long-lived daf-2. WB:WBGene00017500 pud-2.2 Expressed in hypodermis. Is predicted to encode a protein with the following domains: Up-regulated in Daf-2 and Up-Regulated in long-lived daf-2. WB:WBGene00017501 pud-3 Expressed in head; hyp7 syncytium; pm3; and rectal gland cell. Is predicted to encode a protein with the following domains: Up-regulated in Daf-2 and Up-Regulated in long-lived daf-2. WB:WBGene00017502 F16B3.2 Enriched in mechanosensory neurons and pharyngeal gland cell based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on RNA-seq and microarray studies. Is affected by cadmium and Colistin based on RNA-seq and microarray studies. WB:WBGene00017503 nhr-177 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00017504 F16B4.2 Enriched in muscle cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; Rifampin; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: F-box protein she-1-like. WB:WBGene00017505 F16B4.3 Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017506 F16B4.4 Expressed in hypodermis. WB:WBGene00017507 F16B4.5 Predicted to be part of ribonucleoprotein complex. WB:WBGene00017508 F16B4.6 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. Predicted to be located in membrane. WB:WBGene00017509 F16B4.7 Enriched in ABplaapappp; ABpraapappp; PVT; and cholinergic neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including rotenone; Ag nanoparticles; and stavudine based on RNA-seq and microarray studies. WB:WBGene00017510 nhr-178 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in several structures, including ciliated neurons; coelomocyte; intestine; pharynx; and spermatheca. WB:WBGene00017511 srbc-41 Predicted to be located in membrane. WB:WBGene00017512 nhr-179 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in intestine; pharynx; and rectal gland cell. WB:WBGene00017513 F16F9.1 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00017514 F16F9.3 Expressed in amphid sheath cell and phasmid sheath cell. Is predicted to encode a protein with the following domain: EF-hand domain pair. WB:WBGene00017515 F16F9.4 Predicted to enable carboxylic ester hydrolase activity. Predicted to be located in membrane. Is an ortholog of human AADACL2 (arylacetamide deacetylase like 2) and AADACL3 (arylacetamide deacetylase like 3). WB:WBGene00017516 F16G10.1 Enriched in NSM and hypodermis based on tiling array studies. Is affected by drh-3; eat-2; and spn-4 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017517 F16G10.2 Enriched in male based on RNA-seq studies. Is affected by several genes including elt-2; csr-1; and hpl-2 based on tiling array and RNA-seq studies. Is affected by Chlorpyrifos and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017518 F16G10.3 Is affected by rsr-2; mir-34; and elt-2 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017519 hpo-25 Predicted to be located in membrane. WB:WBGene00017520 F16G10.5 Enriched in AFD; NSM; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including methylmercury hydroxide; methylmercuric chloride; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PDZ domain 6; PDZ domain; and PDZ superfamily. WB:WBGene00017521 F16G10.6 Enriched in NSM; intestine; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017522 F16G10.7 Enriched in NSM based on tiling array studies. Is affected by several genes including let-60; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017523 F16G10.8 Enriched in AFD and NSM based on tiling array and RNA-seq studies. Is affected by several genes including elt-2; clk-1; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017524 F16G10.9 Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017525 F16G10.10 Enriched in pharynx and in male based on RNA-seq studies. Is affected by several genes including rrf-3; sir-2.1; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017526 F16G10.11 Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including daf-16; let-60; and daf-12 based on microarray and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; Alovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017527 F16G10.13 Enriched in AVE based on tiling array studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017528 F16G10.14 Enriched in RICL and RICR based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and mex-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00017529 F16G10.15 Enriched in intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; tert-Butylhydroperoxide; and Cadmium Chloride based on microarray and RNA-seq studies. WB:WBGene00017530 mfsd-12 Predicted to enable symporter activity. Predicted to be involved in organic substance transport. Predicted to be located in membrane. Is an ortholog of human MFSD12 (major facilitator superfamily domain containing 12). WB:WBGene00017532 ent-5 Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Is an ortholog of human SLC29A3 (solute carrier family 29 member 3). WB:WBGene00017533 fbxa-178 Enriched in germ line based on RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and aak-2 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; cholesterol; and paraquat based on RNA-seq and microarray studies. WB:WBGene00017534 cwf-19L1 Predicted to enable RNA lariat debranching enzyme activator activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of post-mRNA release spliceosomal complex. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 17. Is an ortholog of human CWF19L1 (CWF19 like cell cycle control factor 1). WB:WBGene00017535 atf-8 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in vulva. WB:WBGene00017536 F17A9.4 Predicted to enable FMN binding activity and oxidoreductase activity. WB:WBGene00017537 F17A9.5 Predicted to enable FMN binding activity and oxidoreductase activity. WB:WBGene00017538 ceh-49 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in coelomocyte; head muscle; head neurons; intestine; and somatic nervous system. WB:WBGene00017539 F17E9.2 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including aldicarb; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00017540 F17E9.3 Involved in defense response to Gram-negative bacterium. Expressed in seminal vesicle. WB:WBGene00017541 F17E9.4 Enriched in dopaminergic neurons; germ line; hypodermis; intestine; and spermatheca based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by twenty-one chemicals including Heme; Ethanol; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Transthyretin-like superfamily; Protein of unknown function DUF870, Caenorhabditis species; and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00017542 F17E9.5 Predicted to be located in membrane. WB:WBGene00017543 lgc-5 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00017544 lgc-6 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00017545 F18A1.1 Predicted to be located in membrane. WB:WBGene00017546 rpa-1 Enables enzyme binding activity. Involved in positive regulation of nematode male tail tip morphogenesis. Located in nucleoplasm. Expressed in germ line. Is an ortholog of human RPA1 (replication protein A1). WB:WBGene00017547 alfa-1 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in autophagy and endocytosis. Predicted to be located in autophagosome and endosome. Expressed widely. Used to study amyotrophic lateral sclerosis. Human ortholog(s) of this gene implicated in frontotemporal dementia and/or amyotrophic lateral sclerosis-1. Is an ortholog of human C9orf72 (C9orf72-SMCR8 complex subunit). WB:WBGene00017548 F18A1.7 Expressed in germ line. Is predicted to encode a protein with the following domain: Chondroitin proteoglycan 4. WB:WBGene00017549 pid-1 Predicted to be involved in regulatory ncRNA-mediated gene silencing. Located in nucleus and perinuclear region of cytoplasm. WB:WBGene00017550 nep-6 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00017551 F18A12.2 Predicted to be located in membrane. WB:WBGene00017552 nep-7 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00017553 nep-8 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00017554 nep-9 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00017555 nep-10 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00017556 F18A12.7 Enriched in Y cell and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and elt-2 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including stavudine; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017557 nep-11 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; artery disease (multiple); congestive heart failure; and dilated cardiomyopathy. Is an ortholog of human ECE1 (endothelin converting enzyme 1). WB:WBGene00017559 mpz-3 Expressed in male gonad. Is predicted to encode a protein with the following domains: Uncharacterized protein T15H9.4-like and PDZ superfamily. WB:WBGene00017560 F18C5.5 Enriched in excretory cell; germline precursor cell; hypodermis; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including methylmercury hydroxide; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00017561 F18C5.7 No description available WB:WBGene00017562 F18C5.9 Enriched in ABplpappaa; excretory cell; interfacial epithelial cell; and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00017563 F18C5.10 Predicted to be located in membrane. WB:WBGene00017564 srxa-4 Predicted to be located in membrane. WB:WBGene00017565 ddo-2 Enables D-aspartate oxidase activity and D-glutamate oxidase activity. Involved in aspartate catabolic process and obsolete oxidation-reduction process. Predicted to be located in cytoplasm. Expressed in body wall musculature; intestinal cell; and pharyngeal muscle cell. WB:WBGene00017566 F18E3.10 Predicted to be located in membrane. WB:WBGene00017567 F18E3.11 Enriched in PLM; SMB; amphid neurons; germline precursor cell; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-six chemicals including hydrogen sulfide; rotenone; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00017568 F18E9.1 Enriched in neurons; rectal epithelial cell; rectum; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including mianserin; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017569 F18E9.3 Enriched in PLM; germ line; germline precursor cell; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017570 F18E9.4 Enriched in interfacial epithelial cell and rectum based on single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and daf-12 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017571 jmjd-3.1 Enables histone H3K27me2/H3K27me3 demethylase activity. Involved in transdifferentiation. Located in nucleus. Expressed in PDA and Y cell. WB:WBGene00017573 F18E9.7 Enriched in germ line; male-specific anatomical entity; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Alovudine; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017574 pxmp-4 Predicted to be located in peroxisomal membrane. Expressed in head. Is an ortholog of human PXMP4 (peroxisomal membrane protein 4). WB:WBGene00017576 cdh-8 Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in plasma membrane. WB:WBGene00017577 F18F11.4 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00017578 drl-1 Predicted to enable ATP binding activity and protein kinase activity. Predicted to be located in membrane. Expressed in body wall musculature; neurons; seam cell; and vulval muscle. WB:WBGene00017579 F18G5.1 Enriched in germ line and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including clk-1; daf-19; and his-72 based on tiling array; microarray; and RNA-seq studies. Is affected by Atrazine based on microarray studies. WB:WBGene00017580 lgc-4 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in head neurons. WB:WBGene00017581 F18G5.5 Enriched in male based on RNA-seq studies. Is affected by several genes including sir-2.1; dpy-21; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Atrazine; Chlorpyrifos; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00017582 F18G5.6 Involved in innate immune response. WB:WBGene00017583 F19B10.1 Enriched in several structures, including GLR; germ line; male distal tip cell; muscle cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including hydrogen sulfide; rotenone; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017584 F19B10.2 Enriched in several structures, including MSpppaaa; germ line; head mesodermal cell; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including hydrogen sulfide; rotenone; and mianserin based on microarray and RNA-seq studies. WB:WBGene00017585 F19B10.3 Is affected by rsr-2; sir-2.1; and eat-2 based on tiling array and microarray studies. Is affected by Atrazine and Sirolimus based on microarray studies. WB:WBGene00017586 F19B10.4 Enriched in several structures, including ABalpapppa; ABarapappa; male distal tip cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; rrf-3; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including methylmercuric chloride; metformin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00017587 F19B10.5 Enriched in several structures, including Z1.p; germ line; germline precursor cell; male distal tip cell; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00017588 F19B10.6 Is affected by several genes including clk-1; hpl-2; and mir-34 based on tiling array and microarray studies. WB:WBGene00017589 F19B10.10 Predicted to be involved in innate immune response. WB:WBGene00017590 F19B10.11 Enriched in ABplpapppa; g2L; g2R; and head mesodermal cell based on single-cell RNA-seq studies. Is affected by several genes including daf-12; lin-4; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; metformin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00017591 nspg-10 Involved in innate immune response. WB:WBGene00017592 F19C7.2 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human PRSS16 (serine protease 16). WB:WBGene00017593 F19C7.3 Enriched in germ line; muscle cell; rectal epithelial cell; rectal muscle; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hpl-2; and cye-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including D-glucose; Alovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00017594 F19C7.4 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human PRSS16 (serine protease 16). WB:WBGene00017597 F19C7.8 Predicted to be involved in positive regulation of protein localization to plasma membrane and skeletal muscle contraction. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in Native American myopathy. Is an ortholog of human STAC (SH3 and cysteine rich domain); STAC2 (SH3 and cysteine rich domain 2); and STAC3 (SH3 and cysteine rich domain 3). WB:WBGene00017598 F19F10.1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00017599 F19F10.3 Enriched in several structures, including amphid sheath cell; enteric muscle; excretory cell; neurons; and rectal muscle based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4440; Domain of unknown function (DUF4440); and NTF2-like domain superfamily. WB:WBGene00017600 ttr-10 Predicted to be located in cell surface and extracellular region. WB:WBGene00017601 ets-7 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in response to oxidative stress. Predicted to be located in nucleus. WB:WBGene00017602 clec-211 Enriched in NSM based on tiling array studies. Is affected by several genes including sir-2.1; mut-2; and set-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine; dafa#1; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00017603 clec-212 Predicted to be located in membrane. WB:WBGene00017605 snu-66 Predicted to be involved in mRNA cis splicing, via spliceosome and maturation of 5S rRNA. Predicted to be located in nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex. Is an ortholog of human SART1 (spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP). WB:WBGene00017606 ets-6 Predicted to be involved in negative regulation of vulval development. WB:WBGene00017607 F19F10.11 Predicted to enable kinase activity. Predicted to be involved in negative regulation of vulval development and phosphorylation. WB:WBGene00017608 ints-9 Predicted to be involved in snRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of integrator complex. Is an ortholog of human INTS9 (integrator complex subunit 9). WB:WBGene00017609 F19G12.1 Predicted to enable metal ion binding activity. WB:WBGene00017610 F19G12.2 Enriched in ABalpppappp; ABpraaaappp; AVK; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; let-60; and sir-2.1 based on RNA-seq and microarray studies. Is affected by Microcystin-LR based on microarray studies. WB:WBGene00017611 F19G12.3 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; AIN; and ciliated neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Lithium Chloride; allantoin; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: PAZ domain superfamily. WB:WBGene00017612 F19G12.4 Enriched in Z1; Z4; intestine; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; Tunicamycin; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00017613 spig-1 Enriched in neuronal sheath cell; sensory neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by eleven chemicals including rotenone; D-glucose; and stavudine based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00017614 F20A1.2 Predicted to be located in membrane. WB:WBGene00017615 srsx-32 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of several human genes including OR2M4 (olfactory receptor family 2 subfamily M member 4); OR5H1 (olfactory receptor family 5 subfamily H member 1); and OR5I1 (olfactory receptor family 5 subfamily I member 1). WB:WBGene00017616 F20A1.4 Predicted to be located in membrane. WB:WBGene00017618 F20A1.6 Enriched in several structures, including dopaminergic neurons; g1P; germ line; mechanosensory neurons; and neuronal sheath cell based on proteomic; microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; silicon dioxide nanoparticle; and paraquat based on RNA-seq; microarray; and proteomic studies. WB:WBGene00017619 F20A1.8 Enriched in muscle cell and sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; nhr-49; and alg-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00017620 tofu-2 Located in cytoplasm. WB:WBGene00017621 txt-17 Enriched in PLM; dopaminergic neurons; intestine; neuronal sheath cell; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including rotenone; D-glucose; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00017622 F20B4.2 No description available WB:WBGene00017625 cgt-2 Predicted to enable ceramide glucosyltransferase activity. Predicted to be involved in glucosylceramide biosynthetic process. Predicted to be located in membrane. Expressed in intestine and vulva. Is an ortholog of human UGCG (UDP-glucose ceramide glucosyltransferase). WB:WBGene00017626 F20B4.7 No description available WB:WBGene00017627 F20B6.1 Is affected by several genes including daf-16; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00017628 F20B6.4 Predicted to be located in membrane. WB:WBGene00017629 F20B6.5 Enriched in germ line based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017630 F20B6.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; multi-walled carbon nanotube; and metformin based on microarray and RNA-seq studies. WB:WBGene00017631 F20B6.7 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including aldicarb; Alovudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00017632 F20B6.9 Enriched in AFD; Caapa; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00017633 F20D6.1 Enriched in AFD; germ line; and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Cry5B; and Doxycycline based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterized protein T15H9.4-like and PDZ superfamily. WB:WBGene00017634 F20D6.2 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00017635 F20D6.5 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00017636 F20D6.6 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00017637 F20D6.8 Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be located in plasma membrane. WB:WBGene00017638 F20D6.9 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in nucleus. Predicted to be part of nucleosome. Is an ortholog of human H3Y1 (H3.Y histone 1). WB:WBGene00017639 F20D6.10 Predicted to be located in membrane. WB:WBGene00017640 F20D6.11 Predicted to enable oxidoreductase activity, acting on NAD(P)H. Predicted to be involved in execution phase of apoptosis. Predicted to be located in endoplasmic reticulum and mitochondrial inner membrane. Expressed in tail. Is an ortholog of human AIFM3 (apoptosis inducing factor mitochondria associated 3). WB:WBGene00017641 csr-1 Enables endoribonuclease activity, cleaving siRNA-paired mRNA. Involved in P granule assembly; mitotic sister chromatid segregation; and siRNA-mediated gene silencing by mRNA destabilization. Located in P granule; condensed nuclear chromosome; and metaphase plate. Expressed in several structures, including germ line and in male. WB:WBGene00017642 mcm-3AP Predicted to be involved in mRNA export from nucleus. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription export complex 2. Expressed in head and tail. Is an ortholog of human MCM3AP (minichromosome maintenance complex component 3 associated protein). WB:WBGene00017643 czw-1 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and mitotic spindle assembly checkpoint signaling. Part of RZZ complex. Is an ortholog of human ZW10 (zw10 kinetochore protein). WB:WBGene00017644 exc-9 Predicted to enable zinc ion binding activity. Involved in anatomical structure morphogenesis; epithelial cell development; and regulation of tube size. Located in cytoplasm. Expressed in several structures, including ALM; distal tip cell; excretory canal; lumbar ganglion; and nerve ring. Is an ortholog of human CRIP1 (cysteine rich protein 1). WB:WBGene00017645 F20D12.7 Predicted to be located in membrane. WB:WBGene00017646 F20H11.1 Predicted to enable metal ion binding activity. Is an ortholog of human DEF8 (differentially expressed in FDCP 8 homolog). WB:WBGene00017647 F20H11.4 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in motor neuron axon guidance. WB:WBGene00017648 ddo-3 Predicted to enable D-amino-acid oxidase activity. Predicted to be involved in D-amino acid catabolic process. Predicted to be located in cytoplasm. Expressed in several structures, including coelomocyte; eggshell; excretory socket cell; non-striated muscle; and seminal vesicle. WB:WBGene00017650 F21A9.1 Enriched in FLP; anterior hypodermis; interfacial epithelial cell; and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including 1-methylnicotinamide; multi-walled carbon nanotube; and stavudine based on RNA-seq and microarray studies. WB:WBGene00017651 F21A9.2 Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. WB:WBGene00017652 F21C10.1 Predicted to be located in membrane. WB:WBGene00017653 F21C10.3 Predicted to be located in membrane. WB:WBGene00017654 F21C10.4 Predicted to be located in membrane. WB:WBGene00017655 F21C10.5 Is affected by several genes including clk-1; hpl-2; and ain-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Sirolimus and allantoin based on microarray studies. WB:WBGene00017656 F21C10.6 Predicted to be located in membrane. WB:WBGene00017657 F21C10.7 Predicted to be involved in axon guidance and cell adhesion. Predicted to be located in plasma membrane. WB:WBGene00017658 F21C10.9 Enriched in ASER; hypodermis; intestine; and mechanosensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by forty-three chemicals including Nitric Oxide; 1-methylnicotinamide; and methylmercuric chloride based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Acyl-CoA N-acyltransferase. WB:WBGene00017659 F21C10.10 Located in mitochondrion. WB:WBGene00017660 F21C10.11 Enriched in amphid sheath cell; dopaminergic neurons; head mesodermal cell; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-five chemicals including diallyl trisulfide; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00017661 frpr-6 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00017662 F21D12.2 Enriched in ABplapapppp and ABprapapppp based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00017663 F21D12.3 Predicted to be located in membrane. Expressed in body wall musculature and motor neurons. WB:WBGene00017664 npax-1 Predicted to enable DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Expressed in head neurons. WB:WBGene00017665 F21E9.1 No description available WB:WBGene00017666 F21E9.2 Predicted to be located in membrane. WB:WBGene00017667 ttr-37 Predicted to be located in cell surface and extracellular region. WB:WBGene00017668 ins-39 Expressed in gonad; intestine; neurons; and pharynx. WB:WBGene00017669 F21E9.5 No description available WB:WBGene00017670 F21E9.6 Enriched in muscle cell; neurons; and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including daf-2; eri-1; and rrf-1 based on microarray studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00017671 pgal-1 Predicted to enable metal ion binding activity and peptidylamidoglycolate lyase activity. Predicted to be involved in peptide metabolic process. Predicted to be located in extracellular region. Expressed in head ganglion; nervous system; and tail ganglion. Human ortholog(s) of this gene implicated in prostate adenocarcinoma. Is an ortholog of human PAM (peptidylglycine alpha-amidating monooxygenase). WB:WBGene00017672 F21F3.2 Predicted to enable MAP kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and nucleus. WB:WBGene00017673 icmt-1 Predicted to enable protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in endoplasmic reticulum. Is an ortholog of human ICMT (isoprenylcysteine carboxyl methyltransferase). WB:WBGene00017674 F21F3.4 Enriched in PLML; PLMR; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF4708) and Domain of unknown function DUF4708. Is an ortholog of human C18orf63 (chromosome 18 open reading frame 63). WB:WBGene00017675 F21F3.6 Predicted to be located in lysosomal membrane. WB:WBGene00017676 F21F3.7 Predicted to be located in membrane. Is an ortholog of human TMEM134 (transmembrane protein 134). WB:WBGene00017677 asp-11 Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Tunicamycin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00017678 asp-12 Predicted to enable aspartic-type endopeptidase activity. Involved in innate immune response. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human REN (renin). WB:WBGene00017679 F21F8.5 Enriched in ADLL; ADLR; germ line; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Zidovudine; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00017680 F21F8.6 Enriched in intestine based on RNA-seq studies. Is affected by several genes including let-60; elt-2; and dpy-7 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube and Sodium Chloride based on RNA-seq studies. WB:WBGene00017681 slc-17.5 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be located in membrane. WB:WBGene00017683 rbbp-5 Involved in several processes, including heterochromatin organization; multicellular organism reproduction; and transdifferentiation. Part of MLL3/4 complex. Is an ortholog of human RBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit). WB:WBGene00017684 F21H12.2 Enriched in dopaminergic neurons and neurons based on tiling array studies. Is affected by several genes including daf-16; sir-2.1; and pqm-1 based on microarray and RNA-seq studies. WB:WBGene00017685 F21H12.3 Is affected by jmjd-3.1; mir-34; and npr-8 based on RNA-seq and microarray studies. Is affected by four chemicals including Tunicamycin; Cry5B; and Colistin based on microarray studies. WB:WBGene00017686 tpp-2 Predicted to enable tripeptidyl-peptidase activity. Involved in positive regulation of lipid storage. Predicted to be located in cytosol. Expressed in intestine and nerve ring. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human TPP2 (tripeptidyl peptidase 2). WB:WBGene00017687 ets-4 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including P1; germ line; head; socket cell; and sperm. Human ortholog(s) of this gene implicated in ovarian cancer. Is an ortholog of human SPDEF (SAM pointed domain containing ETS transcription factor). WB:WBGene00017688 ttr-35 Predicted to be located in cell surface and extracellular region. WB:WBGene00017690 ceh-60 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in dopaminergic neuron differentiation and regulation of transcription by RNA polymerase II. Acts upstream of or within lipid homeostasis. Part of chromatin. Expressed in amphid neurons and sensory neurons. WB:WBGene00017691 ilys-5 Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-positive bacterium. WB:WBGene00017692 F22B7.1 Enriched in anterior ganglion; head mesodermal cell; intestine; muscle cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including Cry5B; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017693 flp-23 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. WB:WBGene00017694 F22B7.3 Expressed in nervous system. Is predicted to encode a protein with the following domains: Family of unknown function (DUF5390) and Protein of unknown function DUF5390. WB:WBGene00017695 fip-1 Enriched in head mesodermal cell and tail precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including tryptophan; Ag nanoparticles; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00017696 polk-1 Predicted to enable DNA-directed DNA polymerase activity. Involved in embryo development; error-prone translesion synthesis; and reproduction. Predicted to be located in nucleus. Is an ortholog of human POLK (DNA polymerase kappa). WB:WBGene00017698 F22B7.9 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including Eala; Ealp; Eara; Earp; and Epla. WB:WBGene00017699 flcn-1 Predicted to contribute to GTPase activator activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of TORC1 signaling; and positive regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in cytosol. Expressed in excretory cell; nervous system; spermatheca; and vulva. Used to study Birt-Hogg-Dube syndrome. Human ortholog(s) of this gene implicated in several diseases, including Birt-Hogg-Dube syndrome; primary spontaneous pneumothorax; and renal cell carcinoma. Is an ortholog of human FLCN (folliculin). WB:WBGene00017700 F22D3.4 Enriched in AVDL; AVDR; DVC; germ line; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00017701 F22D3.5 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalappaap; ABalppappa; and ABalpppappp based on single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by hydrogen sulfide and silicon dioxide nanoparticle based on microarray studies. WB:WBGene00017702 malt-1 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Expressed in RMG and oxygen sensory neurons. Human ortholog(s) of this gene implicated in immunodeficiency 12 and non-Hodgkin lymphoma. Is an ortholog of human MALT1 (MALT1 paracaspase). WB:WBGene00017703 F22E5.1 Predicted to be located in membrane. WB:WBGene00017704 F22E5.2 Enriched in several structures, including AVJ; cholinergic neurons; intestine; rect_D; and rectal epithelial cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including eat-2; pmk-1; and bar-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00017705 F22E5.6 Acts upstream of or within IRE1-mediated unfolded protein response and PERK-mediated unfolded protein response. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00017706 F22E5.7 Enriched in several structures, including ABalpppppa; ABalppppppa; ABalppppppp; RMED; and amphid sheath cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including hsf-1; eat-2; and lin-35 based on microarray and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00017707 F22E5.8 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00017708 F22E5.9 Predicted to be located in membrane. Expressed in several structures, including intestine. WB:WBGene00017709 F22E5.11 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00017710 F22E5.12 Predicted to be involved in protein homooligomerization. Predicted to be located in membrane. WB:WBGene00017711 F22E5.13 Enriched in Z1.p; Z4.a; male distal tip cell; neurons; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; rotenone; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00017712 F22E5.17 Enriched in ABalappaap; AFD; ASER; PLM; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00017713 F22E5.20 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppappa; ABalpppapa; and ciliated neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; mianserin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00017714 F22F1.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00017715 F22F1.3 Predicted to enable transcription coregulator activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00017716 sups-1 Expressed in hypodermal cell. WB:WBGene00017717 F22F4.4 Enriched in head mesodermal cell; hypodermis; neurons; rectal epithelial cell; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00017718 F22F4.5 Enriched in several structures, including ABalppappa; ABarappppa; ABplaapaap; anterior ganglion (post); and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq; tiling array; and microarray studies. Is affected by thirteen chemicals including Tunicamycin; sodium arsenite; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00017719 ldp-1 Predicted to enable oxidoreductase activity. Predicted to be involved in glycolipid biosynthetic process. Predicted to be located in lipid droplet. Expressed in head and tail. Is an ortholog of human SCCPDH (saccharopine dehydrogenase (putative)). WB:WBGene00017720 F22F7.2 Predicted to enable oxidoreductase activity. Predicted to be involved in glycolipid biosynthetic process. Predicted to be located in lipid droplet. Is an ortholog of human SCCPDH (saccharopine dehydrogenase (putative)). WB:WBGene00017721 F22F7.3 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00017722 F22F7.4 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00017723 bgnt-1.2 Enriched in hypodermis and seam cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by fourteen chemicals including methylmercuric chloride; Tunicamycin; and stavudine based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in congenital muscular dystrophy-dystroglycanopathy type A13. Human B4GAT1 enables glucuronosyltransferase activity. Is predicted to encode a protein with the following domain: Glycosyl-transferase for dystroglycan. Is an ortholog of human B4GAT1 (beta-1,4-glucuronyltransferase 1). WB:WBGene00017724 F22F7.7 Predicted to enable gamma-glutamylcyclotransferase activity. Predicted to be involved in glutathione catabolic process. Located in striated muscle dense body. Is an ortholog of human CHAC1 (ChaC glutathione specific gamma-glutamylcyclotransferase 1). WB:WBGene00017725 F22H10.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00017726 F22H10.2 Involved in innate immune response. WB:WBGene00017727 F22H10.3 Enriched in several structures, including head mesodermal cell; neurons; pharyngeal-intestinal valve; rectal epithelial cell; and rectum based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; D-glucopyranose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00017729 F22H10.5 Enriched in NSM and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00017730 F22H10.6 Enriched in several structures, including CAN; distal tip cell; head mesodermal cell; intestine; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017731 F23C8.1 Enriched in several structures, including AVA; Z1.p; germ line; male distal tip cell; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017732 F23C8.3 Enriched in several structures, including ABplpppppp; AFD; RIM; interneuron; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including glp-1; daf-12; and hsf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00017733 ubxn-1 Enables K48-linked polyubiquitin modification-dependent protein binding activity. Involved in masculinization of hermaphroditic germ-line; positive regulation of protein catabolic process; and spermatogenesis. Acts upstream of or within IRE1-mediated unfolded protein response. Located in perinuclear region of cytoplasm. Expressed in several structures, including gonad and spermatocyte. Is an ortholog of human UBXN1 (UBX domain protein 1). WB:WBGene00017734 F23C8.5 Predicted to enable electron transfer activity. Predicted to be involved in amino acid catabolic process and fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Is an ortholog of human ETFB (electron transfer flavoprotein subunit beta). WB:WBGene00017735 did-2 Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Located in endosome membrane. Expressed in several structures, including anal depressor muscle; hypodermis; intestine; nervous system; and vulva. Is an ortholog of human CHMP1B (charged multivesicular body protein 1B). WB:WBGene00017736 F23C8.7 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00017737 F23C8.8 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. WB:WBGene00017738 tipn-1 Predicted to enable DNA binding activity. Predicted to be involved in several processes, including DNA integrity checkpoint signaling; cell cycle phase transition; and replication fork arrest. Predicted to be located in nucleus. Predicted to be part of chromatin and replication fork protection complex. Is an ortholog of human TIPIN (TIMELESS interacting protein). WB:WBGene00017739 F23C8.11 Enriched in AVE based on tiling array studies. Is affected by several genes including aak-2; alg-1; and mex-3 based on RNA-seq and microarray studies. Is affected by mianserin based on RNA-seq studies. WB:WBGene00017741 F23C8.13 Enriched in several structures, including ABplppaaaap; ABprppaaaap; XXX cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including glp-1; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Lithium Chloride; rotenone; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: PDZ superfamily. WB:WBGene00017742 nfyc-1 Enables DNA-binding transcription repressor activity. Involved in regulation of gene expression and tissue development. Located in cytoplasm and perikaryon. Expressed in several structures, including excretory cell; gonad; head neurons; and oocyte. Is an ortholog of human NFYC (nuclear transcription factor Y subunit gamma). WB:WBGene00017743 F23F1.2 Predicted to enable calcium ion binding activity. Predicted to be involved in calcium-ion regulated exocytosis. Predicted to be located in endoplasmic reticulum. WB:WBGene00017744 fbxc-54 Enriched in body wall muscle cell; hypodermis; intestine; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq; microarray; and tiling array studies. Is affected by twelve chemicals including methylmercuric chloride; Psoralens; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00017745 F23F1.4 Enriched in several structures, including ABalaaaarl; ABalaaaarr; accessory cell; anterior hypodermis; and rectal epithelium based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including lin-4; eat-2; and lin-14 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: GM2-AP, lipid-recognition domain superfamily. WB:WBGene00017746 F23F1.5 Predicted to enable RNA binding activity. Predicted to be involved in protein import into nucleus and snRNA import into nucleus. Predicted to be located in cytoplasm and nucleus. Expressed in head. Is an ortholog of human SNUPN (snurportin 1). WB:WBGene00017747 F23F1.6 Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in amino acid transport. Predicted to be located in plasma membrane. Is an ortholog of human SLC7A4 (solute carrier family 7 member 4). WB:WBGene00017748 spp-24 Enriched in several structures, including ABplpaaaap; XXX cell; accessory cell; excretory system; and nerve ring neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Saposin-like. WB:WBGene00017749 rpoa-49 Predicted to enable DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly and transcription elongation by RNA polymerase I. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I complex. Is an ortholog of human POLR1E (RNA polymerase I subunit E). WB:WBGene00017750 F23F1.10 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00017751 F23F12.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC22A15 (solute carrier family 22 member 15) and SVOPL (SVOP like). WB:WBGene00017752 sdz-15 Involved in embryo development. WB:WBGene00017754 chtb-2 Enriched in several structures, including AFD; AVA; male distal tip cell; pharyngeal muscle cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and let-60 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Family of unknown function (DUF5401). WB:WBGene00017755 zip-8 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Expressed in intestinal cell. WB:WBGene00017756 F23F12.12 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00017757 bra-2 Predicted to enable metal ion binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription elongation by RNA polymerase II. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 30 and stomach cancer. Is an ortholog of human ZMYND11 (zinc finger MYND-type containing 11). WB:WBGene00017758 F23H11.2 Predicted to enable RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly and nucleolar large rRNA transcription by RNA polymerase I. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase I core factor complex and RNA polymerase transcription factor SL1 complex. WB:WBGene00017759 sucl-2 Predicted to enable succinate-CoA ligase (ADP-forming) activity and succinate-CoA ligase (GDP-forming) activity. Predicted to be involved in tricarboxylic acid cycle. Predicted to be located in mitochondrion. Predicted to be part of succinate-CoA ligase complex (ADP-forming). Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 9. Is an ortholog of human SUCLG1 (succinate-CoA ligase GDP/ADP-forming subunit alpha). WB:WBGene00017760 F23H11.4 Predicted to enable phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasm. Expressed in body wall musculature; hypodermis; intestine; neurons; and pharynx. Is an ortholog of human ARAP3 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3). WB:WBGene00017761 idpp-13 Enriched in cholinergic neurons; retrovesicular ganglion; and terminal bulb based on single-cell RNA-seq and microarray studies. Is affected by several genes including skn-1; elt-2; and dpy-7 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; cholesterol; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00017762 F23H11.7 Enriched in neurons; retrovesicular ganglion; and terminal bulb based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including aldicarb; 1-methylnicotinamide; and rotenone based on microarray and RNA-seq studies. WB:WBGene00017763 crls-1 Enables cardiolipin synthase activity. Involved in cardiolipin biosynthetic process; regulation of cell population proliferation; and regulation of mitochondrial membrane potential. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 57. Is an ortholog of human CRLS1 (cardiolipin synthase 1). WB:WBGene00017764 F25A2.1 Predicted to be involved in lipid metabolic process. WB:WBGene00017765 gcst-1 Predicted to enable aminomethyltransferase activity and transaminase activity. Predicted to be involved in glycine catabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in glycine encephalopathy. Is an ortholog of human AMT (aminomethyltransferase). WB:WBGene00017766 peli-1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination and regulation of Toll signaling pathway. Expressed in chemosensory neurons; ciliated neurons; and head. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human PELI2 (pellino E3 ubiquitin protein ligase family member 2) and PELI3 (pellino E3 ubiquitin protein ligase family member 3). WB:WBGene00017767 F25B4.4 Enriched in several structures, including germ line; germline precursor cell; muscle cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including rotenone; antimycin; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: P-loop containing nucleoside triphosphate hydrolase. WB:WBGene00017768 prp-39 Predicted to contribute to pre-mRNA 5'-splice site binding activity. Predicted to be involved in mRNA 5'-splice site recognition. Predicted to be part of U1 snRNP; U2-type prespliceosome; and commitment complex. Is an ortholog of human PRPF39 (pre-mRNA processing factor 39). WB:WBGene00017769 hmgs-1 Predicted to enable hydroxymethylglutaryl-CoA synthase activity. Predicted to be involved in acetyl-CoA metabolic process and farnesyl diphosphate biosynthetic process, mevalonate pathway. Human ortholog(s) of this gene implicated in HMG-CoA synthase 2 deficiency and hepatocellular carcinoma. Is an ortholog of human HMGCS2 (3-hydroxy-3-methylglutaryl-CoA synthase 2). WB:WBGene00017770 F25B4.7 Predicted to enable ATP:ADP antiporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6). WB:WBGene00017771 F25B4.8 Predicted to enable carbon-sulfur lyase activity and metal ion binding activity. Is an ortholog of human CENPV (centromere protein V). WB:WBGene00017772 clec-1 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. WB:WBGene00017773 dct-6 Enriched in several structures, including ABarpaapap; anterior hypodermis; g1; sensory neurons; and somatic nervous system based on Chronogram; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including diallyl trisulfide; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: WD40/YVTN repeat-like-containing domain superfamily and WD40-repeat-containing domain superfamily. WB:WBGene00017774 nop-1 Involved in anterior/posterior axis specification, embryo and mitotic cytokinesis. Located in cell cortex; cleavage furrow; and nucleus. Expressed in embryonic cell. WB:WBGene00017775 F25B5.3 Predicted to enable 5'-nucleotidase activity. Predicted to be involved in nucleotide metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human NT5C3A (5'-nucleotidase, cytosolic IIIA). WB:WBGene00017776 F25B5.5 Predicted to enable N6-isopentenyladenosine methylthiotransferase activity. Predicted to be involved in tRNA methylthiolation. Predicted to be located in cytosol and mitochondrion. Is an ortholog of human CDK5RAP1 (CDK5 regulatory subunit associated protein 1). WB:WBGene00017777 F25B5.6 Predicted to enable tetrahydrofolylpolyglutamate synthase activity. Predicted to be involved in tetrahydrofolylpolyglutamate biosynthetic process. Predicted to be located in cytosol and mitochondrion. Is an ortholog of human FPGS (folylpolyglutamate synthase). WB:WBGene00017778 nono-1 Predicted to enable RNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); multiple myeloma; and syndromic X-linked intellectual disability 34. Is an ortholog of human PSPC1 (paraspeckle component 1) and SFPQ (splicing factor proline and glutamine rich). WB:WBGene00017779 gtr-1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in neurons and ventral nerve cord. WB:WBGene00017780 F25E2.2 Enriched in GABAergic neurons and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Mercuric Chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00017781 F25E2.3 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid catabolic process. Predicted to be located in peroxisomal matrix. Is an ortholog of human ACOT8 (acyl-CoA thioesterase 8). WB:WBGene00017782 F25E5.1 Enriched in DD neuron; OLL; PVD; germ line; and sensory neurons based on microarray and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on tiling array; microarray; and RNA-seq studies. Is affected by Humic Substances; paraquat; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domain: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II. WB:WBGene00017783 F25E5.2 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00017784 F25E5.3 Enriched in several structures, including Z1.p; Z4.a; germ line; male distal tip cell; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Peptidase S1, PA clan; Nematode trypsin-6-like family; Chymotrypsin family Peptidase-S1; and Peptidase S1, PA clan, chymotrypsin-like fold. WB:WBGene00017785 F25E5.4 Enriched in Z1.p; Z4.a; male distal tip cell; neurons; and somatic gonad precursor based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; rotenone; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Peptidase S1, PA clan; Nematode trypsin-6-like family; Chymotrypsin family Peptidase-S1; and Peptidase S1, PA clan, chymotrypsin-like fold. WB:WBGene00017786 F25E5.5 Enriched in AVA; Z1.p; Z4.a; male distal tip cell; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: F-box protein she-1-like. WB:WBGene00017787 nhr-141 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00017788 F25E5.7 Enriched in germ line; neurons; and in male based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Peptidase S1, PA clan; Nematode trypsin-6-like family; Chymotrypsin family Peptidase-S1; and Peptidase S1, PA clan, chymotrypsin-like fold. WB:WBGene00017789 F25E5.8 Enriched in several structures, including AVA; G2; W cell; intestine; and mechanosensory neurons based on microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including diallyl trisulfide; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017790 F25E5.9 Enriched in RICL; RICR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including age-1; daf-12; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Atrazine; cadmium; and tetrabromobisphenol A based on microarray studies. WB:WBGene00017791 try-8 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00017792 F25E5.16 Enriched in ABalppappa; ABarappppa; head mesodermal cell; hypodermis; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and TRAF-like. WB:WBGene00017794 mltn-13 Enriched in excretory system; neuronal sheath cell; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; let-60; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including Rifampin; glycine; and cholesterol based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Moulting cycle MLT-10-like protein and Moulting cycle. WB:WBGene00017795 F25F8.1 Enriched in several structures, including anterior hypodermis; excretory cell; neurons; pm8; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; hsf-1; and eat-2 based on RNA-seq; microarray; and proteomic studies. Is affected by twelve chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017796 F25G6.1 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABplpapppa; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; let-60; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00017797 symk-1 Predicted to be involved in mRNA polyadenylation. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is an ortholog of human SYMPK (symplekin scaffold protein). WB:WBGene00017798 slc-17.8 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be located in membrane. WB:WBGene00017799 F25G6.8 Predicted to enable 7S RNA binding activity and endoplasmic reticulum signal peptide binding activity. Predicted to be involved in protein targeting to ER. Predicted to be located in cytoplasm. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is an ortholog of human SRP14 (signal recognition particle 14). WB:WBGene00017800 F25G6.9 Predicted to be involved in protein targeting to ER. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. WB:WBGene00017801 F26A1.1 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalpapppa; AFD; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and gld-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including manganese chloride; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017802 F26A1.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00017803 F26A1.4 Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00017805 F26A1.7 Predicted to be located in membrane. WB:WBGene00017806 F26A1.8 Predicted to be located in membrane. Expressed in head and tail. WB:WBGene00017807 F26A1.9 Enriched in germline precursor cell; hypodermis; male-specific anatomical entity; socket cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017808 nspd-9 Expressed in head. Is predicted to encode a protein with the following domains: Caenorhabditis elegans protein of unknown function (DUF780) and Protein of unknown function DUF780, Caenorhabditis species. WB:WBGene00017809 clec-156 Is affected by rsr-2 based on tiling array studies. Is affected by adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00017810 clec-157 Enriched in URXL; URXR; germ line; neurons; and sensory neurons based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and rrf-3 based on microarray and RNA-seq studies. Is affected by seven chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00017811 nonu-1 Predicted to enable endonuclease activity. Human ortholog(s) of this gene implicated in several diseases, including alcoholic liver cirrhosis; hypomyelinating leukodystrophy 20; and restless legs syndrome. Is an ortholog of several human genes including CNP (2',3'-cyclic nucleotide 3' phosphodiesterase); N4BP2 (NEDD4 binding protein 2); and N4BP2L2 (NEDD4 binding protein 2 like 2). WB:WBGene00017813 nlp-61 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00017814 F26A10.2 Predicted to enable chromatin insulator sequence binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 22 and lethal congenital contracture syndrome. Is an ortholog of human ZBTB18 (zinc finger and BTB domain containing 18); ZBTB42 (zinc finger and BTB domain containing 42); and ZNF148 (zinc finger protein 148). WB:WBGene00017815 F26B1.1 Enriched in several structures, including GLR; NSM; coelomocyte; germ line; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Heme; D-glucose; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00017816 hrpk-1 Predicted to enable mRNA binding activity. Involved in DNA damage response and embryo development. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including hypodermal cell; intestinal cell; muscle cell; neurons; and oocyte. Human ortholog(s) of this gene implicated in Raynaud disease; colorectal cancer; and prostate cancer. Is an ortholog of human HNRNPK (heterogeneous nuclear ribonucleoprotein K). WB:WBGene00017817 F26B1.5 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00017818 F26D11.1 Predicted to enable gluconokinase activity. Predicted to be involved in D-gluconate catabolic process. Is an ortholog of human IDNK (IDNK gluconokinase). WB:WBGene00017819 F26D11.2 Enriched in head mesodermal cell and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including methylmercury hydroxide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00017821 F26D11.4 Enriched in AFD and ASER based on RNA-seq studies. Is affected by several genes including sir-2.1; mex-3; and mex-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00017822 clec-216 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by resveratrol and adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00017823 pals-34 Enriched in several structures, including ABplaapaaa; coelomocyte; germ line; head mesodermal cell; and hyp3 based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00017824 clec-217 Enriched in male-specific anatomical entity; neurons; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00017825 cee-1 Predicted to be involved in protein insertion into ER membrane. Predicted to be located in cytosol. Predicted to be part of BAT3 complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Is an ortholog of human GET4 (guided entry of tail-anchored proteins factor 4). WB:WBGene00017826 tag-340 Predicted to enable lipid binding activity. Predicted to be involved in vesicle tethering to endoplasmic reticulum. Predicted to be located in endoplasmic reticulum membrane; endoplasmic reticulum-endosome membrane contact site; and late endosome membrane. Is an ortholog of human STARD3 (StAR related lipid transfer domain containing 3). WB:WBGene00017827 F26F4.5 Predicted to be involved in actin cytoskeleton organization. Predicted to be located in microtubule organizing center. Predicted to be part of filamentous actin. Human ortholog(s) of this gene implicated in Teebi hypertelorism syndrome 1 and oblique facial clefting 1. Is an ortholog of human SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1 like). WB:WBGene00017828 F26F4.6 Expressed in head. WB:WBGene00017829 F26F4.9 Predicted to be involved in intracellular protein transport. Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00017830 rpb-8 Predicted to enable DNA binding activity and DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase I; transcription by RNA polymerase II; and transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Is an ortholog of human POLR2H (RNA polymerase II, I and III subunit H). WB:WBGene00017831 F26F4.12 Enriched in germ line and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-2; let-7; and gld-1 based on proteomic; RNA-seq; and microarray studies. Is affected by nine chemicals including rotenone; bisphenol S; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ankyrin repeats (3 copies); Ankyrin repeat-containing domain superfamily; and Ankyrin repeat. Is an ortholog of human ANKRD49 (ankyrin repeat domain 49). WB:WBGene00017832 kbp-2 Involved in kinetochore assembly. Located in kinetochore. WB:WBGene00017833 F26F12.2 Enriched in ABalappaap; neurons; and in male based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including methylmercuric chloride; multi-walled carbon nanotube; and atracurium based on microarray and RNA-seq studies. WB:WBGene00017834 F26F12.3 Enriched in several structures, including ABalaaaala; ADE sheath cell; ganglia; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-six chemicals including Ethanol; 1-methylnicotinamide; and methylmercuric chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00017835 F26F12.4 Predicted to be located in membrane. WB:WBGene00017836 F26F12.5 Involved in defense response to Gram-negative bacterium. WB:WBGene00017837 F26G1.1 Predicted to be involved in endocytic recycling. Predicted to be located in endosome. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome. Is an ortholog of human VPS35L (VPS35 endosomal protein sorting factor like). WB:WBGene00017838 F26G1.2 Enriched in germline precursor cell; hypodermis; neurons; and somatic gonad precursor based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including rotenone; Tunicamycin; and 4-bromodiphenyl ether based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017839 F26G1.3 Is affected by several genes including elt-2; sir-2.1; and pmk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Transthyretin-like superfamily. WB:WBGene00017840 ttm-2 Involved in response to nematicide. Predicted to be located in cytoplasm. WB:WBGene00017841 F26G1.5 Enriched in germline precursor cell; hypodermis; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-seven chemicals including 1-methylnicotinamide; rotenone; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00017842 nep-12 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Is an ortholog of human KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00017843 F26G5.1 Expressed in germ line. WB:WBGene00017845 srsx-9 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00017846 F27B3.4 No description available WB:WBGene00017848 F27B3.6 Enriched in AIAL; AIAR; GABAergic neurons; RMED; and RMEV based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00017849 F27B3.7 Enriched in AVA and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including aldicarb; rotenone; and mianserin based on microarray and RNA-seq studies. WB:WBGene00017850 F27B10.1 Predicted to be located in membrane. WB:WBGene00017851 F27C1.1 Enriched in AFD; amphid sheath cell; germ line; and sperm based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty-two chemicals including Ethanol; 1-methylnicotinamide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00017852 F27C1.2 Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in copper ion transmembrane transport and intracellular copper ion homeostasis. Predicted to be located in late endosome membrane. Is an ortholog of human SLC31A1 (solute carrier family 31 member 1). WB:WBGene00017853 F27C1.3 Enriched in amphid sheath cell; germ line; and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; methylmercuric chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: DUF236 repeat. WB:WBGene00017854 F27C1.4 Enriched in ABalpppapa; ABpraaaapa; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on RNA-seq; tiling array; and microarray studies. Is affected by twelve chemicals including rotenone; mianserin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017855 F27C1.6 Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human UTP14A (UTP14A small subunit processome component) and UTP14C (UTP14C small subunit processome component). WB:WBGene00017858 F27C1.11 Predicted to be involved in intracellular signal transduction. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy; autosomal recessive nonsyndromic deafness 77; and orofacial cleft. Is an ortholog of human LOXHD1 (lipoxygenase homology PLAT domains 1). WB:WBGene00017860 F27C1.13 Predicted to be involved in intracellular signal transduction. Predicted to be located in cell projection and cytoplasm. WB:WBGene00017861 F27D9.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00017864 pcca-1 Predicted to enable propionyl-CoA carboxylase activity. Predicted to be involved in lipid catabolic process. Located in mitochondrion. Expressed in head and neurons. Used to study propionic acidemia. Human ortholog(s) of this gene implicated in propionic acidemia. Is an ortholog of human PCCA (propionyl-CoA carboxylase subunit alpha). WB:WBGene00017865 F27D9.7 Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. Predicted to be located in membrane. Is an ortholog of human ADAMDEC1 (ADAM like decysin 1). WB:WBGene00017866 stn-2 Enables cell adhesion molecule binding activity. Located in several cellular components, including cell body; neuron projection; and sarcomere. Expressed in body wall musculature; enteric muscle; neurons; and vulva. Used to study Duchenne muscular dystrophy. Is an ortholog of human SNTG1 (syntrophin gamma 1). WB:WBGene00017867 slc-28.1 Predicted to enable nucleoside:sodium symporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human SLC28A1 (solute carrier family 28 member 1) and SLC28A2 (solute carrier family 28 member 2). WB:WBGene00017868 slc-28.2 Predicted to enable nucleoside:sodium symporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human SLC28A1 (solute carrier family 28 member 1) and SLC28A2 (solute carrier family 28 member 2). WB:WBGene00017869 F28A10.1 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00017870 F28A10.2 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; aak-2; and let-418 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017871 F28A10.3 Predicted to be located in membrane. WB:WBGene00017872 F28A10.4 Enriched in RIML; RIMR; germ line; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00017873 F28A10.5 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00017874 acdh-9 Predicted to enable flavin adenine dinucleotide binding activity and oxidoreductase activity, acting on the CH-CH group of donors. Is an ortholog of human ACAD8 (acyl-CoA dehydrogenase family member 8). WB:WBGene00017875 F28A10.7 Predicted to be located in membrane. WB:WBGene00017876 F28A10.8 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00017877 F28A10.9 Is affected by several genes including lin-4; eat-2; and lin-14 based on RNA-seq and microarray studies. Is affected by six chemicals including glycine; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00017878 F28A10.10 Is affected by several genes including clk-1; aak-2; and hpl-2 based on microarray and RNA-seq studies. Is affected by fluoranthene and adsorbable organic bromine compound based on microarray studies. WB:WBGene00017879 acd-4 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of human ASIC1 (acid sensing ion channel subunit 1); ASIC2 (acid sensing ion channel subunit 2); and ASIC3 (acid sensing ion channel subunit 3). WB:WBGene00017880 F28A12.3 Predicted to be located in membrane. Expressed in inner labial neurons and outer labial neurons. WB:WBGene00017881 asp-13 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. WB:WBGene00017885 dip-2 Expressed in hypodermal cell and neurons. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Is predicted to encode a protein with the following domains: ANL, N-terminal domain; AMP-binding enzyme; AMP-dependent synthetase/ligase domain; and AMP-binding enzyme, C-terminal domain superfamily. Is an ortholog of human DIP2A (disco interacting protein 2 homolog A); DIP2B (disco interacting protein 2 homolog B); and DIP2C (disco interacting protein 2 homolog C). WB:WBGene00017886 mfsd-13.1 Predicted to be located in membrane. Is an ortholog of human MFSD13A (major facilitator superfamily domain containing 13A). WB:WBGene00017887 F28B3.6 Predicted to be located in membrane. WB:WBGene00017888 acl-11 Predicted to enable acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Predicted to be located in endoplasmic reticulum and mitochondrion. Is an ortholog of human AGPAT5 (1-acylglycerol-3-phosphate O-acyltransferase 5). WB:WBGene00017889 F28B3.10 Predicted to be located in membrane. WB:WBGene00017890 F28B4.1 Predicted to be located in membrane. WB:WBGene00017891 rgl-1 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in epidermal growth factor receptor signaling pathway and positive regulation of vulval development. Predicted to be located in plasma membrane. Expressed in germ cell; somatic cell; and vulval precursor cell. Is an ortholog of human RGL1 (ral guanine nucleotide dissociation stimulator like 1) and RGL3 (ral guanine nucleotide dissociation stimulator like 3). WB:WBGene00017892 F28B4.3 Enriched in AFD; PLM; RMED; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-three chemicals including rotenone; manganese chloride; and mianserin based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; C-type lectin-like; von Willebrand factor A-like domain superfamily; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; MD domain; EGF-like domain; and Phosphorylation site. WB:WBGene00017893 F28B4.4 Predicted to be located in membrane. WB:WBGene00017894 F28B12.1 Enriched in several structures, including Z1.p; intestine; male distal tip cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by allantoin and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00017895 vrk-1 Enables protein kinase activity. Involved in several processes, including cell fate specification; gonad development; and regulation of fibroblast growth factor receptor signaling pathway. Located in nuclear envelope. Part of chromatin. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; hermaphrodite gonad; and ventral nerve cord. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1A. Is an ortholog of human VRK1 (VRK serine/threonine kinase 1). WB:WBGene00017896 F28C10.1 Enriched in AVEL; AVER; and coelomocyte based on tiling array and single-cell RNA-seq studies. Is affected by several genes including eat-2; lin-15B; and met-2 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00017897 F28C10.2 No description available WB:WBGene00017898 F28C10.3 Predicted to enable ribosomal protein S6 kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cytoplasm and nucleoplasm. WB:WBGene00017899 F28C10.4 Enriched in AVEL; AVER; and NSM based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Testosterone and Sirolimus based on microarray studies. WB:WBGene00017900 F28E10.1 Enriched in XXX cell; head mesodermal cell; neurons; retrovesicular ganglion; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017901 igeg-1 Predicted to be located in membrane. WB:WBGene00017902 F28E10.4 Enriched in amphid sheath cell; germ line; nerve ring neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Uncharacterized protein T15H9.4-like. WB:WBGene00017904 lim-8 Enables protein domain specific binding activity. Predicted to be involved in positive regulation of stress fiber assembly and regulation of focal adhesion assembly. Located in M band. Expressed in excretory canal; head neurons; non-striated muscle; spermatheca; and vulva. Is an ortholog of human LIMCH1 (LIM and calponin homology domains 1). WB:WBGene00017905 F28F5.6 Enriched in several structures, including AFD; head mesodermal cell; pharynx; rectal epithelial cell; and rectal gland cell based on Chronogram; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; D-glucopyranose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017906 F28F9.2 Predicted to be located in membrane. WB:WBGene00017907 F28F9.3 Enriched in several structures, including anterior arcade cell; cephalic sheath cell; excretory gland cell; neurons; and pm8 based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; glp-1; and aak-2 based on microarray; tiling array; and RNA-seq studies. Is affected by Rifampin; allantoin; and cholesterol based on RNA-seq studies. WB:WBGene00017908 F28H1.1 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalpapaap; male distal tip cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; Mercuric Chloride; and D-glucopyranose based on RNA-seq and microarray studies. WB:WBGene00017909 F28H1.4 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human CMTM8 (CKLF like MARVEL transmembrane domain containing 8). WB:WBGene00017910 F28H1.5 Enriched in several structures, including ABplpaaaap; ABprpaaaap; AFD; MSpaapaa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including tryptophan; methylmercuric chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00017911 fbxb-106 Enriched in several structures, including ABalppppaa; ABalpppppa; ABalppppppa; ABplaapappp; and head neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00017912 fbxb-107 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; ABalappppaa; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; mianserin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00017913 F29A7.3 Enriched in NSM and neurons based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; hda-1; and set-2 based on tiling array and RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00017914 F29A7.4 Predicted to enable type 1 cannabinoid receptor binding activity. Predicted to be located in plasma membrane. Is an ortholog of human CNRIP1 (cannabinoid receptor interacting protein 1). WB:WBGene00017916 F29A7.6 Predicted to be involved in maturation of 5.8S rRNA. Expressed widely. Is an ortholog of human MPHOSPH6 (M-phase phosphoprotein 6). WB:WBGene00017917 clec-120 Is affected by several genes including daf-2; sir-2.1; and mex-3 based on RNA-seq and microarray studies. Is affected by Mercuric Chloride and allantoin based on microarray studies. WB:WBGene00017918 F29A7.8 Enriched in head neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and resveratrol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00017919 F29B9.1 Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in cytoplasm. Is an ortholog of human EEF1AKMT2 (EEF1A lysine methyltransferase 2). WB:WBGene00017920 jmjd-1.2 Enables histone H3K27me2/H3K27me3 demethylase activity; histone H3K9 demethylase activity; and histone binding activity. Involved in mitochondrial unfolded protein response. Located in nucleus. Expressed in several structures, including germ cell; hypodermis; muscle cell; and neurons. Used to study syndromic X-linked intellectual disability. Human ortholog(s) of this gene implicated in melanoma; prostate cancer; and syndromic X-linked intellectual disability Siderius type. Is an ortholog of human KDM7A (lysine demethylase 7A). WB:WBGene00017921 F29B9.5 Predicted to be involved in photoreceptor cell maintenance and sensory perception. Is an ortholog of human NXNL2 (nucleoredoxin like 2). WB:WBGene00017922 F29B9.7 Predicted to be located in membrane. WB:WBGene00017923 F29B9.8 Located in plasma membrane. Expressed in several structures, including hypodermis. WB:WBGene00017924 mrps-21 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS21 (mitochondrial ribosomal protein S21). WB:WBGene00017925 F29B9.11 Predicted to be located in membrane. WB:WBGene00017926 cox-6C Predicted to be located in mitochondrial inner membrane. Expressed in several structures, including body wall musculature; coelomocyte; pharynx; spermatheca; and vulva. WB:WBGene00017927 F29C4.4 Enriched in germ line and neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube and resveratrol based on RNA-seq and microarray studies. WB:WBGene00017928 tut-1 Enables sulfurtransferase activity and tRNA binding activity. Involved in several processes, including gamete generation; tRNA modification; and vulval development. Predicted to be located in cytosol. Predicted to be part of cytosolic tRNA wobble base thiouridylase complex. Is an ortholog of human CTU1 (cytosolic thiouridylase subunit 1). WB:WBGene00017929 grld-1 Predicted to enable RNA binding activity. Located in nucleus. Expressed in epithelial cell; lateral ganglion; muscle cell; and neurons. Is an ortholog of human RBM15 (RNA binding motif protein 15) and RBM15B (RNA binding motif protein 15B). WB:WBGene00017930 F29G9.1 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; amphid neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; D-glucose; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00017931 picc-1 Predicted to be located in adherens junction. Is an ortholog of human CCDC85C (coiled-coil domain containing 85C). WB:WBGene00017933 F29G9.7 Enriched in several structures, including ABalpppppp; ABpraaappp; NSM; excretory system; and germ line based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and lin-4 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; stavudine; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00017934 osgn-1 Predicted to enable oxidoreductase activity. Is an ortholog of human OSGIN1 (oxidative stress induced growth inhibitor 1) and OSGIN2 (oxidative stress induced growth inhibitor family member 2). WB:WBGene00017935 srbc-70 Predicted to be located in membrane. WB:WBGene00017936 zipt-2.2 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human SLC39A1 (solute carrier family 39 member 1) and SLC39A2 (solute carrier family 39 member 2). WB:WBGene00017937 F30H5.3 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00017938 F31A3.3 Enriched in coelomocyte and neurons based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including multi-walled carbon nanotube; D-glucose; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00017939 F31A3.5 Enriched in several structures, including ABaraapapaa; RIS; anterior ganglion (post); germ line; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and npr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Cry5B; silicon dioxide nanoparticle; and paraquat based on microarray and RNA-seq studies. WB:WBGene00017941 F31A9.2 Enriched in PVD and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; tph-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00017942 fbxc-37 Enriched in ABplpapapa; ABprpapapa; arcade cell; and body wall muscle cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; indole; and stavudine based on RNA-seq and microarray studies. WB:WBGene00017943 F31A9.6 No description available WB:WBGene00017944 F31D5.1 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00017945 F31D5.2 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00017947 mth-2 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in X-linked congenital bilateral absence of vas deferens and vibratory urticaria. Is an ortholog of human ADGRE2 (adhesion G protein-coupled receptor E2); ADGRG2 (adhesion G protein-coupled receptor G2); and ADGRG7 (adhesion G protein-coupled receptor G7). WB:WBGene00017948 mth-1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00017949 F31D5.6 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABplpppppp; GLR; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00017950 F31E3.2 Predicted to enable protein kinase activity. Predicted to be involved in phosphorylation. Is an ortholog of human RSKR (ribosomal protein S6 kinase related). WB:WBGene00017951 panl-2 Predicted to enable nucleic acid binding activity. Predicted to contribute to poly(A)-specific ribonuclease activity. Involved in reproduction. Predicted to be located in P-body. Predicted to be part of PAN complex. Is an ortholog of human PAN2 (poly(A) specific ribonuclease subunit PAN2). WB:WBGene00017952 F31E3.6 Predicted to be located in membrane. WB:WBGene00017954 F31E8.4 Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in copper ion transmembrane transport and intracellular copper ion homeostasis. Predicted to be located in late endosome membrane. Is an ortholog of human SLC31A1 (solute carrier family 31 member 1) and SLC31A2 (solute carrier family 31 member 2). WB:WBGene00017955 F31E8.5 Enriched in ABalaaaala; ABalaapaaa; germ line; hypodermis; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00017956 F31E8.6 Is affected by several genes including sir-2.1; smg-2; and mrps-5 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00017957 F31F4.1 Predicted to be located in membrane. WB:WBGene00017959 ugt-42 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1). WB:WBGene00017960 F31F4.11 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00017961 nhr-180 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in intestine. WB:WBGene00017962 fbxa-72 Enriched in several structures, including Z1.p; body wall muscle cell from C lineage; intestine; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-four chemicals including Tunicamycin; sodium arsenite; and indole based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00017963 F31F4.17 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00017964 F31F7.1 Involved in innate immune response. WB:WBGene00017965 F31F7.2 Predicted to be located in membrane. WB:WBGene00017967 ada-2 Predicted to enable chromatin binding activity and transcription coactivator activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of SAGA-type complex. Is an ortholog of human TADA2B (transcriptional adaptor 2B). WB:WBGene00017968 skpo-3 Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in extracellular space. WB:WBGene00017969 ctsa-3.1 Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. Human ortholog(s) of this gene implicated in galactosialidosis. Is an ortholog of human CTSA (cathepsin A). WB:WBGene00017970 F32A5.4 Predicted to be located in extracellular region. WB:WBGene00017971 F32A5.8 Enriched in several structures, including ABplppppaa; XXX cell; interfacial epithelial cell; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including rotenone; stavudine; and allantoin based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and short chain dehydrogenase. Is an ortholog of human WWOX (WW domain containing oxidoreductase). WB:WBGene00017973 ift-81 Predicted to enable tubulin binding activity. Involved in chemotaxis; detection of stimulus involved in sensory perception; and intraciliary transport. Located in non-motile cilium. Expressed in amphid neurons; chemosensory neurons; and phasmid neurons. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 19 with or without polydactyly. Is an ortholog of human IFT81 (intraflagellar transport 81). WB:WBGene00017974 vps-41 Predicted to enable metal ion binding activity. Involved in negative regulation of apoptotic process; vacuolar protein processing; and vacuolar transport. Predicted to be located in late endosome. Predicted to be part of HOPS complex. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 29. Is an ortholog of human VPS41 (VPS41 subunit of HOPS complex). WB:WBGene00017975 F32B5.1 Predicted to enable kinase activity. Predicted to be involved in phosphocreatine biosynthetic process and phosphorylation. Is an ortholog of several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1B (creatine kinase, mitochondrial 1B). WB:WBGene00017976 F32B5.2 Enriched in mechanosensory neurons and neurons based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00017977 F32B5.3 Predicted to be located in membrane. WB:WBGene00017978 msrp-1 Enriched in germ line; seam cell; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and pie-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-six chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00017979 F32B5.6 Enriched in CAN; coelomocyte; intestine; mechanosensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on proteomic; microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Lithium Chloride; Cry5B; and stavudine based on microarray and RNA-seq studies. WB:WBGene00017980 F32B5.7 Enriched in head mesodermal cell; muscle cell; neurons; pharyngeal cell; and retrovesicular ganglion based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Glycine-rich domain-containing protein-like. WB:WBGene00017981 figl-1 Enables ATP hydrolysis activity; magnesium ion binding activity; and microtubule binding activity. Involved in ATP metabolic process and positive regulation of mitotic cell cycle. Located in nucleus. Expressed in germ line. Is an ortholog of human FIGNL1 (fidgetin like 1). WB:WBGene00017982 hpo-18 Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1). Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Is an ortholog of human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2). WB:WBGene00017983 F32D1.3 Predicted to enable mannosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human TMTC2 (transmembrane O-mannosyltransferase targeting cadherins 2). WB:WBGene00017984 gmpr-1 Predicted to enable GMP reductase activity and metal ion binding activity. Predicted to be involved in purine nucleobase metabolic process and purine nucleotide metabolic process. Predicted to be part of GMP reductase complex. Is an ortholog of human GMPR (guanosine monophosphate reductase). WB:WBGene00017985 neg-1 Located in nucleus. Expressed in AB lineage cell; ABa; ABp; and Psub1. WB:WBGene00017986 F32D1.7 Enriched in several structures, including ABalapppaa; germ line; male distal tip cell; neurons; and somatic gonad precursor based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on RNA-seq; microarray; and proteomic studies. Is affected by eighteen chemicals including manganese chloride; bisphenol A; and Linolenic Acids based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00017987 F32D1.8 Enriched in several structures, including XXX cell; amphid neurons; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00017988 fipp-1 Predicted to be located in nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is an ortholog of human FIP1L1 (factor interacting with PAPOLA and CPSF1). WB:WBGene00017989 nol-10 Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human NOL10 (nucleolar protein 10). WB:WBGene00017990 cec-4 Enables methylated histone binding activity. Involved in chromosome attachment to the nuclear envelope; regulation of cell differentiation; and regulation of gene expression. Located in nuclear inner membrane. Expressed in germ cell and somatic cell. WB:WBGene00017991 clec-180 Predicted to enable carbohydrate binding activity. Predicted to be located in extracellular region. WB:WBGene00017992 F32E10.5 Enriched in several structures, including ABalaapppa; ABalapaapa; germ line; male distal tip cell; and nerve ring neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and sir-2.1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Tudor domain and RING finger protein 17. WB:WBGene00017993 cec-5 Predicted to enable methylated histone binding activity. Predicted to be involved in chromosome attachment to the nuclear envelope and regulation of gene expression. Predicted to be located in nuclear inner membrane. WB:WBGene00017995 F32E10.8 Enriched in GLR; MSpppaaa; coelomocyte; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; pgl-1; and alg-1 based on tiling array and RNA-seq studies. Is affected by six chemicals including Zidovudine; Rifampin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: LDL receptor-like superfamily; Low-density lipoprotein receptor domain class A; and Low-density lipoprotein (LDL) receptor class A repeat. WB:WBGene00017996 F33D4.4 Predicted to enable sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 18. Is an ortholog of human DEGS1 (delta 4-desaturase, sphingolipid 1) and DEGS2 (delta 4-desaturase, sphingolipid 2). WB:WBGene00017997 mrpl-1 Predicted to be located in ribosome. Is an ortholog of human MRPL1 (mitochondrial ribosomal protein L1). WB:WBGene00017998 F33D4.6 Enriched in several structures, including CEP socket cell; arc ant V; germline precursor cell; hypodermis; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-eight chemicals including Ethanol; Nitric Oxide; and methylmercury hydroxide based on RNA-seq and microarray studies. WB:WBGene00017999 emc-6 Predicted to be involved in autophagosome assembly. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of EMC complex. Is an ortholog of human EMC6 (ER membrane protein complex subunit 6). WB:WBGene00018000 F33D11.1 Predicted to enable metal ion binding activity. WB:WBGene00018001 F33D11.2 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00018002 twk-47 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Is an ortholog of human KCNK17 (potassium two pore domain channel subfamily K member 17) and KCNK5 (potassium two pore domain channel subfamily K member 5). WB:WBGene00018003 F33D11.6 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including sir-2.1; set-2; and mir-34 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Atrazine; and cadmium based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Family of unknown function (DUF5382) and Protein of unknown function DUF5382. WB:WBGene00018004 F33D11.7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00018005 nlp-62 Involved in defense response to Gram-negative bacterium. WB:WBGene00018006 gpaa-1 Predicted to be involved in attachment of GPI anchor to protein. Predicted to be located in membrane. Predicted to be part of GPI-anchor transamidase complex. Is an ortholog of human GPAA1 (glycosylphosphatidylinositol anchor attachment 1). WB:WBGene00018007 F33D11.10 Predicted to enable RNA helicase activity and mRNA binding activity. Involved in nuclear mRNA surveillance. Predicted to be located in nucleolus. Predicted to be part of catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in intellectual disability and pancreatic cancer. Is an ortholog of human EIF4A3 (eukaryotic translation initiation factor 4A3). WB:WBGene00018008 vpr-1 Enables ephrin receptor binding activity and protein domain specific binding activity. Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum-plasma membrane tethering. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Expressed in several structures, including body wall musculature; gonad; intestine; muscle cell; and nervous system. Used to study amyotrophic lateral sclerosis. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 8 and autosomal dominant adult-onset proximal spinal muscular atrophy. Is an ortholog of human VAPA (VAMP associated protein A) and VAPB (VAMP associated protein B and C). WB:WBGene00018009 dhhc-3 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Is an ortholog of human ZDHHC3 (zinc finger DHHC-type palmitoyltransferase 3). WB:WBGene00018010 F33E11.2 Enriched in DVA; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on RNA-seq and microarray studies. Is affected by seventeen chemicals including rotenone; manganese chloride; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00018011 F33E11.3 Predicted to be located in early endosome. Is an ortholog of human PPP1R21 (protein phosphatase 1 regulatory subunit 21). WB:WBGene00018013 phf-10 Predicted to enable metal ion binding activity. Predicted to be involved in nervous system development. Predicted to be located in nucleus. Used to study alcohol use disorder. Is an ortholog of human PHF10 (PHD finger protein 10). WB:WBGene00018014 wdr-83 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human WDR83 (WD repeat domain 83). WB:WBGene00018015 F33G12.3 Enriched in several structures, including germ line; head mesodermal cell; mechanosensory neurons; rectal epithelial cell; and rectum based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including Zidovudine; metformin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Family of unknown function (DUF5614); Domain of unknown function DUF5614; Protein of unknown function (DUF1308); Domain of unknown function DUF1308; and Phosphorylation site. Is an ortholog of human C7orf25 (chromosome 7 open reading frame 25). WB:WBGene00018016 lrr-1 Involved in mitotic DNA replication checkpoint signaling. Located in nucleus. Is an ortholog of human LRR1 (leucine rich repeat protein 1). WB:WBGene00018017 golg-2 Predicted to be involved in Golgi organization. Predicted to be located in Golgi cis cisterna; Golgi cisterna membrane; and cis-Golgi network. Expressed in head ganglion; motor neurons; pharyngeal neurons; and tail neurons. Is an ortholog of human GOLGA2 (golgin A2). WB:WBGene00018018 F33G12.6 Enriched in several structures, including germ line; head ganglion; head mesodermal cell; interfacial epithelial cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; sir-2.1; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including rotenone; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein phosphatase 2C; PPM-type phosphatase-like domain; PPM-type phosphatase-like domain superfamily; and Phosphorylation site. WB:WBGene00018019 F33H12.1 Is affected by several genes including let-60; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Alovudine; Doxycycline; and resveratrol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BRCA1 C Terminus (BRCT) domain; BRCT domain superfamily; and BRCT domain. WB:WBGene00018020 F33H12.6 No description available WB:WBGene00018021 F34D6.1 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalppappa; NSM; and amphid neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; Mercuric Chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; F-box domain; and Phosphorylation site. WB:WBGene00018022 ceh-87 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in central nervous system development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head neurons; rectal gland cell; and tail neurons. WB:WBGene00018023 set-11 Predicted to enable p53 binding activity; protein methyltransferase activity; and zinc ion binding activity. Involved in innate immune response. Predicted to be located in chromosome and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Kleefstra syndrome 1; esophagus squamous cell carcinoma; and lung disease (multiple). Is an ortholog of human EHMT1 (euchromatic histone lysine methyltransferase 1) and EHMT2 (euchromatic histone lysine methyltransferase 2). WB:WBGene00018024 F35A5.1 Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in intermediate filament bundle assembly. Predicted to be located in neurofilament. Human ortholog(s) of this gene implicated in several diseases, including Creutzfeldt-Jakob disease; autoimmune disease of the nervous system (multiple); and neuropathy (multiple). Is an ortholog of human NEFH (neurofilament heavy chain). WB:WBGene00018025 F35A5.2 Enriched in PVR; distal tip cell; and g1 based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including D-glucose; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018026 idpp-5 Expressed in pharynx. Is predicted to encode a protein with the following domains: Cysteine rich repeat, tripleX and Cysteine rich repeat. WB:WBGene00018027 F35A5.5 Enriched in arc ant V; hyp1; and hyp2 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; D-glucose; and stavudine based on microarray and RNA-seq studies. WB:WBGene00018029 F35B3.2 No description available WB:WBGene00018030 F35B3.3 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be located in cytoplasm. WB:WBGene00018031 F35B3.4 Enriched in amphid socket cell; cholinergic neurons; hypodermis; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty chemicals including Heme; hydrogen sulfide; and Nitric Oxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00018032 F35B3.6 No description available WB:WBGene00018033 F35B3.7 Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in breast carcinoma; esophageal cancer; and squamous cell carcinoma. Is an ortholog of human LZTS1 (leucine zipper tumor suppressor 1) and LZTS2 (leucine zipper tumor suppressor 2). WB:WBGene00018034 sek-5 Predicted to enable MAP kinase kinase activity. Predicted to be involved in stress-activated MAPK cascade. WB:WBGene00018035 sek-4 Predicted to enable MAP kinase kinase activity. Predicted to be involved in stress-activated MAPK cascade. WB:WBGene00018036 F35C8.5 Predicted to enable C-4 methylsterol oxidase activity. Predicted to be involved in sterol biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human CH25H (cholesterol 25-hydroxylase). WB:WBGene00018037 chtl-1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in germ line. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 72. Is an ortholog of human SLC44A2 (solute carrier family 44 member 2). WB:WBGene00018038 F35C8.8 Enriched in AVE; AVK; GABAergic neurons; muscle cell; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including eat-2; clk-1; and csr-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00018039 F35D2.1 Enriched in OLL; PVD; head mesodermal cell; and hypodermis based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including Ethanol; methylmercury hydroxide; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00018040 F35D2.2 Enriched in several structures, including ABalapaaaa; ABalappapa; AVK; XXX cell; and rect_D based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercury hydroxide; manganese chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00018041 F35D2.3 Predicted to be located in membrane. WB:WBGene00018042 mks-3 Involved in non-motile cilium assembly. Located in ciliary transition zone. Expressed in neurons. Used to study Meckel syndrome. Human ortholog(s) of this gene implicated in several diseases, including Bardet-Biedl syndrome 14; COACH syndrome; and Joubert syndrome 6. Is an ortholog of human TMEM67 (transmembrane protein 67). WB:WBGene00018043 F35D11.1 Enriched in several structures, including ciliated neurons; distal tip cell; enteric muscle; germ line; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00018044 F35D11.3 Predicted to be located in membrane. Is an ortholog of human TMCO4 (transmembrane and coiled-coil domains 4). WB:WBGene00018045 F35D11.4 Predicted to enable pyrophosphatase activity. WB:WBGene00018046 coa-3 Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COA3 (cytochrome c oxidase assembly factor 3). WB:WBGene00018047 clec-136 Enriched in male-specific anatomical entity; sensory neurons; and in male based on RNA-seq and microarray studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C-type lectin fold. WB:WBGene00018048 clec-137 Expressed in vas deferens. Is predicted to encode a protein with the following domain: C-type lectin fold. WB:WBGene00018049 clec-138 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C-type lectin fold. WB:WBGene00018050 clec-139 Enriched in arc ant V and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including bisphenol A; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and Phosphorylation site. WB:WBGene00018051 che-10 Involved in cilium assembly. Located in ciliary basal body and ciliary transition zone. Is an ortholog of human CEP250 (centrosomal protein 250) and CROCC (ciliary rootlet coiled-coil, rootletin). WB:WBGene00018052 F35F10.1 Predicted to enable hydrolase activity. Predicted to be involved in glycoprotein catabolic process. Predicted to be located in cytoplasm. WB:WBGene00018053 srbc-3 Predicted to be located in membrane. WB:WBGene00018054 F35F10.4 Enriched in OLL; PVD; body wall muscle cell; and head mesodermal cell based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018055 F35F10.5 Enriched in ASER; RIH; body wall muscle cell; hypodermis; and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including Ethanol; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00018056 F35F10.6 Predicted to enable cysteine-type peptidase activity. Predicted to be involved in proteolysis. WB:WBGene00018057 F35F10.7 Predicted to enable cysteine-type peptidase activity. Predicted to be involved in proteolysis. WB:WBGene00018058 srbc-1 Predicted to be located in membrane. WB:WBGene00018059 F35F10.10 Is affected by several genes including daf-16; daf-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00018060 arrd-18 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC2 (arrestin domain containing 2). WB:WBGene00018061 arrd-19 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC2 (arrestin domain containing 2). WB:WBGene00018062 F35F10.13 Enriched in muscle cell and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; Tunicamycin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00018063 F35F10.14 Predicted to be located in membrane. WB:WBGene00018064 cdc-73 Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in positive regulation of transcription elongation by RNA polymerase II and recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex. Predicted to be located in nucleus. Predicted to be part of Cdc73/Paf1 complex. Human ortholog(s) of this gene implicated in carcinoma (multiple); colorectal cancer; and hyperparathyroidism. Is an ortholog of human CDC73 (cell division cycle 73). WB:WBGene00018065 F35F11.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including manganese chloride; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018066 F35F11.3 Enriched in URY and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and alg-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00018067 npr-7 Predicted to enable neuropeptide binding activity and neuropeptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection and plasma membrane. Human ortholog(s) of this gene implicated in artery disease (multiple); lipid metabolism disorder; and obesity. Is an ortholog of human NPY5R (neuropeptide Y receptor Y5) and PRLHR (prolactin releasing hormone receptor). WB:WBGene00018068 F35H10.2 Enriched in neurons; ventral nerve cord; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including manganese chloride; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018069 F35H10.3 Enriched in several structures, including arcade cell; hyp3; mechanosensory neurons; pharyngeal muscle cell; and pharyngeal-intestinal valve based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; multi-walled carbon nanotube; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018070 F35H10.5 Predicted to enable DNA binding activity. Predicted to be involved in replication fork processing and resolution of meiotic recombination intermediates. Predicted to be part of FANCM-MHF complex and Fanconi anaemia nuclear complex. Is an ortholog of human CENPX (centromere protein X). WB:WBGene00018071 F35H10.6 Predicted to enable unfolded protein binding activity. Predicted to be involved in RNA polymerase I assembly; RNA polymerase II core complex assembly; and RNA polymerase III assembly. Predicted to be located in cytoplasm. Predicted to be part of prefoldin complex. Is an ortholog of human UXT (ubiquitously expressed prefoldin like chaperone). WB:WBGene00018072 nprl-3 Predicted to be involved in several processes, including TORC1 signaling; cellular response to amino acid starvation; and negative regulation of TORC1 signaling. Predicted to be located in lysosomal membrane. Predicted to be part of GATOR1 complex. Human ortholog(s) of this gene implicated in focal epilepsy. Is an ortholog of human NPRL3 (NPR3 like, GATOR1 complex subunit). WB:WBGene00018073 F35H10.10 Predicted to enable G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential; adenylate cyclase inhibiting G protein-coupled glutamate receptor activity; and neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to be located in postsynaptic density membrane. WB:WBGene00018074 F35H12.1 Predicted to be involved in positive regulation of hippo signaling. Predicted to be located in cell junction and plasma membrane. Is an ortholog of human IQCJ-SCHIP1 (IQCJ-SCHIP1 readthrough) and SCHIP1 (schwannomin interacting protein 1). WB:WBGene00018075 tbc-11 Predicted to enable GTPase activator activity. Involved in RNA localization and cuticle development. Is an ortholog of human RABGAP1 (RAB GTPase activating protein 1) and RABGAP1L (RAB GTPase activating protein 1 like). WB:WBGene00018076 pifk-1 Predicted to enable 1-phosphatidylinositol 4-kinase activity. Involved in regulation of basement membrane organization. Predicted to be located in cytoplasm and membrane. Expressed in head and tail. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness. Is an ortholog of human PI4KB (phosphatidylinositol 4-kinase beta). WB:WBGene00018077 F35H12.5 Predicted to enable hydrolase activity. WB:WBGene00018078 F35H12.6 Predicted to be located in membrane. WB:WBGene00018080 F36A4.1 Enriched in ADLL; ADLR; amphid sheath cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including D-glucose; antimycin; and Doxycycline based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00018081 F36A4.2 Enriched in ADL; NSM; arcade cell; coelomocyte; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including Heme; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00018082 F36A4.3 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; D-glucose; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00018083 F36A4.4 Enriched in dopaminergic neurons; sperm; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00018084 F36A4.5 Enriched in ABalppppppp; ABpraaapppp; XXXL; XXXR; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00018085 ttr-20 Predicted to be located in cell surface and extracellular region. WB:WBGene00018087 F36D4.1 Enriched in germ line; neurons; ventral nerve cord; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; D-glucose; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00018088 trpp-4 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be part of TRAPP complex. Is an ortholog of human TRAPPC4 (trafficking protein particle complex subunit 4). WB:WBGene00018089 F36D4.4 Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection. WB:WBGene00018090 F36D4.5 Predicted to enable deubiquitinase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human DESI2 (desumoylating isopeptidase 2). WB:WBGene00018091 F36D4.6 Enriched in AIML; AIMR; F cell; U cell; and body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-12; drh-3; and mir-34 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including tryptophan; multi-walled carbon nanotube; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00018092 F36F12.1 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00018093 F36F12.2 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00018094 F36F12.3 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00018096 clec-207 Expressed in vas deferens. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00018097 clec-208 Enriched in germ line; neurons; and in male based on proteomic; tiling array; RNA-seq; and microarray studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including multi-walled carbon nanotube; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00018098 F36F12.7 Enriched in seam cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; D-glucose; and antimycin based on microarray and RNA-seq studies. WB:WBGene00018099 ztf-28 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine. WB:WBGene00018100 math-26 Enriched in AIN; head mesodermal cell; intestine; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and dpy-10 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including D-glucose; levamisole; and stavudine based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00018101 math-27 Enriched in AFD; OLL; PVD; head mesodermal cell; and intestine based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including rotenone; Cry5B; and levamisole based on RNA-seq and microarray studies. WB:WBGene00018102 math-28 Enriched in several structures, including ABplpapppa; ABplpppppp; ABprpppppp; dopaminergic neurons; and mechanosensory neurons based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; Sodium Chloride; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00018103 F36H5.4 Predicted to be located in membrane. WB:WBGene00018104 fbxb-53 Acts upstream of or within ATF6-mediated unfolded protein response. WB:WBGene00018105 clec-19 Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including methylmercuric chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00018106 F36H5.8 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalpapaap; interfacial epithelial cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including metformin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018107 F36H5.9 Is affected by several genes including eat-2; clk-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018108 F36H5.10 Predicted to be located in membrane. WB:WBGene00018109 fbxb-12 Is affected by several genes including daf-2; eat-2; and sek-1 based on proteomic; microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; indole; and stavudine based on RNA-seq and microarray studies. WB:WBGene00018110 F36H9.1 Enriched in neurons based on RNA-seq studies. Is affected by drh-3; nfki-1; and qui-1 based on RNA-seq studies. WB:WBGene00018111 F36H9.2 Enriched in PHB; neurons; and seam cell based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018112 F36H9.4 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00018113 F36H9.5 Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00018114 srt-41 Predicted to be located in membrane. Expressed in AWCL and AWCR. WB:WBGene00018115 F36H9.7 Predicted to be involved in regulation of cholinergic synaptic transmission and sleep. WB:WBGene00018117 nlp-47 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00018118 slfl-4 Enriched in anal sphincter muscle; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including manganese chloride; bisphenol S; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018119 F36H12.3 Predicted to be located in cytoskeleton. WB:WBGene00018120 F36H12.4 Enriched in AVG; RIM; command interneuron; germline precursor cell; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018121 F36H12.5 Enriched in AFD; body wall muscle cell; germ line; hypodermis; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including Ethanol; rotenone; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018122 ttbk-2.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00018123 F36H12.9 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00018124 F36H12.10 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00018125 rmd-4 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Ethanol; methylmercuric chloride; and iron oxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00018127 F36H12.14 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and let-60 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including tryptophan; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00018130 F36H12.17 Predicted to be located in membrane. WB:WBGene00018131 F37A4.1 Predicted to enable acylglycerol lipase activity and phospholipase activity. Predicted to be involved in monoacylglycerol catabolic process and phosphatidylserine catabolic process. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 86. Is an ortholog of human ABHD16A (abhydrolase domain containing 16A, phospholipase). WB:WBGene00018132 F37A4.2 Predicted to enable double-stranded RNA binding activity; protein kinase binding activity; and protein kinase inhibitor activity. Predicted to be located in nucleolus. Is an ortholog of human PRKRIP1 (PRKR interacting protein 1). WB:WBGene00018133 F37A4.3 Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. WB:WBGene00018134 F37A4.4 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-six chemicals including hydrogen sulfide; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function WSN; Domain of unknown function; BRCT domain; BRCA1 C Terminus (BRCT) domain; BRCT domain superfamily; Ankyrin repeat-containing domain superfamily; and Ankyrin repeat. WB:WBGene00018135 F37A4.5 Predicted to enable metallopeptidase activity and proteasome binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of proteasome regulatory particle, lid subcomplex. WB:WBGene00018136 F37A4.6 Enriched in germ line; intestine; and neurons based on Chronogram; RNA-seq; single-cell RNA-seq; proteomic; and microarray studies. Is affected by several genes including eat-2; pgl-1; and aak-2 based on RNA-seq and microarray studies. Is affected by Colistin based on microarray studies. WB:WBGene00018137 bath-41 Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to be located in cytoplasm and nucleus. WB:WBGene00018138 folt-2 Predicted to enable folic acid binding activity and vitamin transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in biotin-responsive basal ganglia disease. Is an ortholog of human SLC19A3 (solute carrier family 19 member 3). WB:WBGene00018139 sre-24 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00018140 F37B4.10 Expressed in head muscle; head neurons; tail neurons; and ventral nerve cord. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018141 oac-21 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00018142 oac-22 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00018143 oac-23 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00018144 F37C4.4 Predicted to be located in membrane. WB:WBGene00018145 F37C4.5 Enriched in several structures, including head mesodermal cell; neurons; rectal gland cell; retrovesicular ganglion; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; RNA-seq; tiling array; and microarray studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; D-glucose; and stavudine based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4139; Conserved hypothetical protein CHP02231; and Domain of unknown function (DUF4139). WB:WBGene00018146 F37C4.6 Predicted to enable oxidoreductase activity. Is an ortholog of human PYROXD2 (pyridine nucleotide-disulphide oxidoreductase domain 2). WB:WBGene00018148 F37C4.8 Predicted to be located in membrane. WB:WBGene00018149 yju-2 Predicted to enable metal ion binding activity. Predicted to be involved in RNA splicing. Predicted to be located in nucleus. Predicted to be part of U2-type catalytic step 1 spliceosome. Expressed in tail. Is an ortholog of human YJU2 (YJU2 splicing factor homolog). WB:WBGene00018150 epg-4 Involved in macroautophagy and negative regulation of autophagosome assembly. Located in endoplasmic reticulum. Expressed in several structures, including body wall musculature; head; hypodermis; pharyngeal muscle cell; and tail. Is an ortholog of human EI24 (EI24 autophagy associated transmembrane protein). WB:WBGene00018151 ndab-2 Predicted to enable acyl binding activity and acyl carrier activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Is an ortholog of human NDUFAB1 (NADH:ubiquinone oxidoreductase subunit AB1). WB:WBGene00018152 acs-4 Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process; long-chain fatty-acyl-CoA metabolic process; and neuron differentiation. Located in lipid droplet. Expressed in hypodermis; intestine; pharynx; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including lung cancer; non-syndromic X-linked intellectual disability 63; and prostate cancer. Is an ortholog of human ACSL3 (acyl-CoA synthetase long chain family member 3) and ACSL4 (acyl-CoA synthetase long chain family member 4). WB:WBGene00018153 F37C12.10 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABprpaaapa; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including aldicarb; methylmercuric chloride; and stavudine based on microarray and RNA-seq studies. WB:WBGene00018154 exos-9 Predicted to be involved in RNA metabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1D. Is an ortholog of human EXOSC9 (exosome component 9). WB:WBGene00018155 F37C12.14 Enriched in germ line and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-35 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00018156 ncbp-1 Predicted to enable RNA cap binding activity and mRNA binding activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be located in nucleus. Predicted to be part of mRNA cap binding activity complex and nuclear cap binding activity complex. Is an ortholog of human NCBP1 (nuclear cap binding protein subunit 1). WB:WBGene00018157 lron-6 Predicted to be located in membrane. Expressed in nerve ring neurons; retrovesicular ganglion neurons; and ventral nerve cord. WB:WBGene00018158 comp-1 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Expressed in spermatid; spermatocyte; and in male. WB:WBGene00018159 F37F2.2 Predicted to enable 7S RNA binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Predicted to be located in cytoplasm and nucleolus. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is an ortholog of human SRP19 (signal recognition particle 19). WB:WBGene00018160 odr-8 Enables deUFMylase activity. Involved in several processes, including positive regulation of chemotaxis; protein localization to non-motile cilium; and response to ethanol. Located in protein-containing complex. Expressed in amphid neurons and phasmid neurons. Used to study early infantile epileptic encephalopathy. Human ortholog(s) of this gene implicated in Beukes hip dysplasia and developmental and epileptic encephalopathy 106. Is an ortholog of human UFSP2 (UFM1 specific peptidase 2). WB:WBGene00018161 F38A5.2 Enriched in several structures, including ABalpapppa; ABarapappa; germ line; mechanosensory neurons; and rectal epithelium based on Chronogram; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and sir-2.1 based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by five chemicals including aldicarb; paraquat; and Chlorpyrifos based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TraB/PryY-like; TraB/PrgY/GumN family; TraB/PrgY/gumN family; and Phosphorylation site. Is an ortholog of human TRABD (TraB domain containing). WB:WBGene00018162 nspb-3 Enriched in GABAergic neurons based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on quantitative PCR; microarray; and RNA-seq studies. Is affected by eighteen chemicals including aldicarb; D-glucose; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00018163 F38A5.6 Predicted to be located in cytoplasm. WB:WBGene00018164 sup-36 Involved in embryonic digestive tract development. Expressed in pharynx. WB:WBGene00018165 F38A5.8 Predicted to be located in membrane. WB:WBGene00018166 nspb-5 Enriched in pharyngeal muscle cell and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on quantitative PCR; microarray; and RNA-seq studies. Is affected by Doxycycline and Colistin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00018167 nspb-4 Enriched in germ line and pharynx based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; quantitative PCR; and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; D-glucose; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00018168 irld-7 Predicted to be located in membrane. WB:WBGene00018169 nspb-2 Enriched in pharynx based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on quantitative PCR; microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Ethanol; multi-walled carbon nanotube; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00018170 nspb-1 Enriched in pharynx; rect_D; rect_VL; rect_VR; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on quantitative PCR; tiling array; RNA-seq; and microarray studies. Is affected by nineteen chemicals including Tunicamycin; multi-walled carbon nanotube; and Vitamin B 12 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00018172 F38B6.2 Enriched in cholinergic neurons; mechanosensory neurons; pharyngeal-intestinal valve; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Zidovudine; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018173 F38B6.3 Predicted to be located in membrane. WB:WBGene00018174 F38B6.4 Predicted to enable phosphoribosylamine-glycine ligase activity and phosphoribosylformylglycinamidine cyclo-ligase activity. Predicted to be involved in adenine biosynthetic process and purine nucleotide biosynthetic process. Predicted to be located in cytosol. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in Down syndrome. Is an ortholog of human GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase). WB:WBGene00018175 F38B6.6 Predicted to enable dolichyl-phosphate-mannose-protein mannosyltransferase activity. Predicted to be involved in endoplasmic reticulum unfolded protein response and protein O-linked mannosylation. Predicted to be located in endoplasmic reticulum. Is an ortholog of human TMTC4 (transmembrane O-mannosyltransferase targeting cadherins 4). WB:WBGene00018176 F38B6.7 Enriched in NSM; RIH; pharyngeal-intestinal valve; and pm7 based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018178 F38E1.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00018179 F38E1.6 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00018180 srsx-22 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00018181 mpdu-1 Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation If. Is an ortholog of human MPDU1 (mannose-P-dolichol utilization defect 1). WB:WBGene00018182 F38E1.10 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including eat-2; tph-1; and lin-35 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00018184 F38E9.1 Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Is an ortholog of human PLCXD2 (phosphatidylinositol specific phospholipase C X domain containing 2) and PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3). WB:WBGene00018185 F38E9.3 No description available WB:WBGene00018186 F38E9.4 Enriched in muscle cell based on microarray studies. Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq; microarray; and proteomic studies. Is affected by metformin; Sirolimus; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018187 twf-2 Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in actin filament depolymerization and regulation of cellular component organization. Predicted to be located in actin filament and myofibril. Expressed in hypodermis and intestine. Is an ortholog of human TWF2 (twinfilin actin binding protein 2). WB:WBGene00018188 F38E9.6 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00018189 nhr-181 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons; intestine; neurons; and tail neurons. WB:WBGene00018190 F38H12.5 Predicted to be located in membrane. WB:WBGene00018191 frpr-7 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in ADE and interneuron. WB:WBGene00018192 F39B3.3 Enriched in germ line and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; bar-1; and cyc-1 based on microarray and RNA-seq studies. Is affected by hydrogen sulfide and cadmium based on microarray studies. WB:WBGene00018193 F39C12.1 Predicted to be involved in cellular response to amino acid starvation and positive regulation of TORC1 signaling. Predicted to be located in cytoplasm. Is an ortholog of human MIOS (meiosis regulator for oocyte development). WB:WBGene00018194 F39E9.1 Enriched in head mesodermal cell; intestine; rect_D; rect_VL; and rect_VR based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Heme; D-glucopyranose; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00018195 btb-16 Enriched in several structures, including ABarppaapp; ABarpppapp; dopaminergic neurons; head mesodermal cell; and mechanosensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including Tunicamycin; mianserin; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00018196 nep-13 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00018197 F39E9.5 No description available WB:WBGene00018198 F39E9.6 Enriched in AFD; AVK; body wall muscle cell; motor neurons; and pharynx based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00018199 F39E9.7 Enriched in XXXL; XXXR; head mesodermal cell; intestine; and pharynx based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018200 btb-17 Enriched in ASER; PQR; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Tunicamycin; and mianserin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00018201 btb-18 Enriched in AMshL; AMshR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; csr-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube and antimycin based on RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00018202 F39F10.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00018203 F39F10.3 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00018204 F39F10.4 Enriched in several structures, including ABalppappa; XXX cell; amphid neurons; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; stavudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00018205 F39F10.5 Predicted to be located in membrane. WB:WBGene00018206 ugt-61 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including Crigler-Najjar syndrome; carcinoma (multiple); and female reproductive organ cancer (multiple). Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00018207 F39G3.2 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00018208 F39G3.3 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00018209 F39G3.4 Predicted to enable oxidoreductase activity. Predicted to be located in membrane. Is an ortholog of human CYB561 (cytochrome b561) and CYBRD1 (cytochrome b reductase 1). WB:WBGene00018210 F39G3.5 Predicted to enable oxidoreductase activity. Involved in innate immune response. Predicted to be located in membrane. Is an ortholog of human CYB561 (cytochrome b561) and CYBRD1 (cytochrome b reductase 1). WB:WBGene00018211 oac-24 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00018212 F39H12.1 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by six chemicals including D-glucose; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018213 wdr-54 Enriched in AWA and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and elt-2 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Human WDR54 enables protein homodimerization activity. Is predicted to encode a protein with the following domains: WD40 repeat; WD40/YVTN repeat-like-containing domain superfamily; and WD40-repeat-containing domain superfamily. Is an ortholog of human WDR54 (WD repeat domain 54). WB:WBGene00018214 F39H12.3 Predicted to enable calmodulin binding activity. Human ortholog(s) of this gene implicated in Merkel cell carcinoma. Is an ortholog of human SPA17 (sperm autoantigenic protein 17). WB:WBGene00018215 igcm-1 Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in cell-cell junction. Expressed in several structures, including interfacial epithelial cell; intestine; labial sensillum; neurons; and pharynx. WB:WBGene00018216 F40A3.1 Involved in innate immune response. WB:WBGene00018217 F40A3.2 Predicted to be located in membrane. WB:WBGene00018218 F40A3.3 Predicted to enable lipid binding activity. Located in mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease; ovarian cancer; and prostate cancer. Is an ortholog of human PEBP1 (phosphatidylethanolamine binding protein 1). WB:WBGene00018219 F40A3.4 Predicted to be located in membrane. WB:WBGene00018221 F40A3.6 Enriched in PLM; head mesodermal cell; muscle cell; and nerve ring neurons based on RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including methylmercuric chloride; rotenone; and allantoin based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018222 F40A3.7 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00018223 bath-13 Enriched in ABplpaaaap; ABprpaaaap; coelomocyte; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eleven chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00018224 bath-18 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and fog-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Alovudine; and Rifampin based on RNA-seq studies. WB:WBGene00018225 nep-14 Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including hydrogen sulfide; methylmercuric chloride; and Mercuric Chloride based on microarray and RNA-seq studies. WB:WBGene00018226 F40B5.2 Predicted to enable hydrolase activity and metal ion binding activity. Predicted to be located in membrane. Is an ortholog of human TMPPE (transmembrane protein with metallophosphoesterase domain). WB:WBGene00018227 nep-15 Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00018228 F40C5.1 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00018229 F40C5.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and lin-35 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00018230 mage-1 Expressed in hypodermis. Is predicted to encode a protein with the following domain: MAGE homology domain, winged helix WH2 motif. WB:WBGene00018231 F40E3.3 Enriched in body wall muscle cell and hypodermis based on tiling array studies. Is affected by several genes including daf-2; mir-34; and set-6 based on microarray and RNA-seq studies. Is affected by aldicarb based on microarray studies. WB:WBGene00018232 F40E3.5 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00018233 F40E3.6 Enriched in anterior arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on microarray; RNA-seq; and tiling array studies. Is affected by five chemicals including Tunicamycin; sodium arsenite; and Chlorpyrifos based on microarray and RNA-seq studies. WB:WBGene00018234 F40E12.1 Enriched in neurons and somatic gonad precursor based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; mex-3; and mex-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and dibromoacetic acid based on RNA-seq and microarray studies. WB:WBGene00018235 F40E12.2 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including hydrogen sulfide; methylmercuric chloride; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00018236 fbxb-71 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaaaa; ABplpaaapa; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Mercuric Chloride; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00018237 irg-7 Predicted to enable carbohydrate binding activity. Predicted to be involved in innate immune response. Predicted to be located in extracellular region. WB:WBGene00018238 F40F4.7 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be involved in mitotic sister chromatid cohesion. Predicted to be part of NatA complex. Is an ortholog of human NAA50 (N-alpha-acetyltransferase 50, NatE catalytic subunit). WB:WBGene00018239 sec-20 Predicted to enable SNAP receptor activity. Predicted to be involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in endoplasmic reticulum. Predicted to be part of SNARE complex. Human ortholog(s) of this gene implicated in Down syndrome. Is an ortholog of human BNIP1 (BCL2 interacting protein 1). WB:WBGene00018240 cox-17 Predicted to enable copper chaperone activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human COX17 (cytochrome c oxidase copper chaperone COX17). WB:WBGene00018241 F40G9.5 Predicted to be located in membrane. WB:WBGene00018242 F40G9.6 Predicted to be located in membrane. WB:WBGene00018243 F40G9.7 Enriched in XXXL; XXXR; male-specific anatomical entity; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; stavudine; and allantoin based on RNA-seq studies. WB:WBGene00018244 F40G9.8 Predicted to be located in membrane. WB:WBGene00018245 F40G9.9 Predicted to be located in membrane. WB:WBGene00018246 clec-148 Predicted to enable signaling receptor activity. WB:WBGene00018247 F40G9.12 Predicted to enable metal ion binding activity. WB:WBGene00018248 F40G9.14 Predicted to enable metal ion binding activity. WB:WBGene00018249 F40H3.1 Enriched in ADE sheath cell; germline precursor cell; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and fog-2 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00018250 F40H3.2 Enriched in several structures, including accessory cell; arc ant V; hyp3; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018251 F40H3.3 Enriched in several structures, including ABarpaapap; ABarpaappa; accessory cell; excretory system; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercury hydroxide; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018252 F40H3.6 Enriched in several structures, including ABalpapaap; ABarappaap; ABplapppapp; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including rotenone; Zidovudine; and cholesterol based on RNA-seq studies. WB:WBGene00018253 F40H6.1 Predicted to be located in membrane. WB:WBGene00018254 F40H6.2 Enriched in AFD; RID; neurons; posterior arcade cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; lin-35; and alg-1 based on RNA-seq and microarray studies. Is affected by fluoranthene based on microarray studies. WB:WBGene00018255 F40H6.5 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00018256 cutl-28 Predicted to be involved in proteolysis. Predicted to be located in extracellular region and membrane. WB:WBGene00018257 F41B4.1 Enriched in head mesodermal cell and muscle cell based on tiling array; RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; proteomic; and RNA-seq studies. Is affected by twelve chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018258 F41B4.2 Enriched in head mesodermal cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; D-glucose; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF5354 and Family of unknown function (DUF5354). WB:WBGene00018259 F41B4.3 Involved in endoplasmic reticulum unfolded protein response. Acts upstream of or within IRE1-mediated unfolded protein response. WB:WBGene00018260 cyp-33C7 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00018261 cyp-33C5 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00018262 cyp-33C3 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00018263 F41B5.6 No description available WB:WBGene00018264 cyp-33C6 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00018265 nhr-182 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00018266 nhr-183 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons; tail neurons; and ventral nerve cord. WB:WBGene00018267 F41C3.1 Enriched in Z1; Z4; and hypodermis based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including 1-methylnicotinamide; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1265 and Protein of unknown function (DUF1265). WB:WBGene00018268 F41C3.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in body wall musculature and uterine muscle. WB:WBGene00018269 acs-11 Predicted to enable medium-chain fatty acid-CoA ligase activity. Involved in IRE1-mediated unfolded protein response. Expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in combined malonic and methylmalonic acidemia. Is an ortholog of human ACSF3 (acyl-CoA synthetase family member 3). WB:WBGene00018270 eas-1 Involved in Golgi vesicle transport. Located in cis-Golgi network. Expressed widely. Is an ortholog of human GOLT1A (golgi transport 1A) and GOLT1B (golgi transport 1B). WB:WBGene00018271 ctsa-1.1 Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Expressed in gonad. Human ortholog(s) of this gene implicated in galactosialidosis. Is an ortholog of human CTSA (cathepsin A). WB:WBGene00018273 F41C3.7 Enriched in several structures, including ABarppaapp; ABarpppapp; neurons; rectal epithelial cell; and rectum based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including tryptophan; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00018274 F41C3.8 Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in membrane. Expressed in I3 neuron; I6 neuron; and pharyngeal muscle cell. WB:WBGene00018275 F41C3.11 Predicted to enable transferase activity. Predicted to be located in membrane. WB:WBGene00018278 F41C6.4 Predicted to be located in plasma membrane. WB:WBGene00018279 F41C6.6 Enriched in ABplpppaaa and ABprpppaaa based on single-cell RNA-seq studies. Is affected by several genes including daf-16; nhr-49; and daf-18 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00018280 F41C6.7 Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in membrane. WB:WBGene00018281 tbc-18 Predicted to enable GTPase activator activity. Is an ortholog of human SGSM3 (small G protein signaling modulator 3). WB:WBGene00018282 F41D9.2 Enriched in several structures, including ABalapapapa; ABalapppapa; ABplpaaappa; ABprpaaappa; and rectal epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including rotenone; D-glucopyranose; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: DOMON domain. WB:WBGene00018283 sulp-3 Predicted to enable salt transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Predicted to be located in membrane. Expressed in pm3; pm4; pm5; pm6; and pm7. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 61 and spermatogenic failure 3. Is an ortholog of several human genes including SLC26A6 (solute carrier family 26 member 6); SLC26A7 (solute carrier family 26 member 7); and SLC26A9 (solute carrier family 26 member 9). WB:WBGene00018284 F41E6.1 Predicted to be located in membrane. WB:WBGene00018285 smk-1 Predicted to enable protein phosphatase activator activity. Involved in several processes, including defense response to bacterium; negative regulation of mitotic DNA damage checkpoint; and response to radiation. Located in nucleus. Expressed in hypodermis; intestine; and tail. Is an ortholog of human PPP4R3A (protein phosphatase 4 regulatory subunit 3A) and PPP4R3B (protein phosphatase 4 regulatory subunit 3B). WB:WBGene00018286 F41E6.5 Predicted to enable FMN binding activity and oxidoreductase activity. Predicted to be located in peroxisome. Is an ortholog of human HAO1 (hydroxyacid oxidase 1). WB:WBGene00018288 F41E6.7 Enriched in anal depressor muscle; anal sphincter muscle; arcade cell; intestinal muscle; and pharyngeal-intestinal valve cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including aak-2; hsp-6; and unc-30 based on microarray and RNA-seq studies. Is affected by twelve chemicals including aldicarb; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00018289 F41E6.8 Enriched in PLM; hyp4; hyp5; hyp6; and ventral cord blast cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; antimycin; and glycine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00018290 vps-60 Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and vesicle budding from membrane. Predicted to be located in multivesicular body. Is an ortholog of human CHMP5 (charged multivesicular body protein 5). WB:WBGene00018291 fip-4 Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00018292 idpc-2 Involved in endoplasmic reticulum unfolded protein response. Acts upstream of or within IRE1-mediated unfolded protein response. WB:WBGene00018293 F41E6.12 Enriched in germline precursor cell; hypodermis; mechanosensory neurons; and rectal epithelial cell based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including rotenone; Tunicamycin; and D-glucopyranose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018294 atg-18 Enables phosphatidylinositol phosphate binding activity. Involved in several processes, including determination of adult lifespan; gamete generation; and xenophagy. Acts upstream of or within with a positive effect on plasma membrane repair. Located in phagocytic vesicle. Expressed in several structures, including head and tail. Used to study Huntington's disease. Is an ortholog of human WIPI2 (WD repeat domain, phosphoinositide interacting 2). WB:WBGene00018295 oac-29 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00018296 F41F3.1 Predicted to be located in membrane. WB:WBGene00018297 F41F3.3 Enriched in arc ant V; hypodermis; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirty chemicals including Nitric Oxide; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq and microarray studies. WB:WBGene00018298 nlp-50 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00018300 F41G3.3 Enriched in g2L; g2R; pharyngeal-intestinal valve; pm6; and pm7 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018301 F41G3.5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00018302 F41G3.6 Enriched in ABplapaaap; ABprapaaap; germ line; intestine; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including hsf-1; let-7; and gld-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by eight chemicals including Zidovudine; metformin; and allantoin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018303 F41G3.10 Enriched in several structures, including AVG; command interneuron; g1; germ line; and touch receptor neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; rotenone; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: CC domain; ShK domain-like; and ShKT domain. WB:WBGene00018304 agr-1 Enables dystroglycan binding activity. Predicted to be involved in cell differentiation. Located in basement membrane. Expressed in hermaphrodite distal tip cell; hyp7 syncytium; motor neurons; and pharynx. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 8. Is an ortholog of human AGRN (agrin). WB:WBGene00018305 exos-8 Predicted to be involved in RNA metabolic process. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1C. Is an ortholog of human EXOSC8 (exosome component 8). WB:WBGene00018307 dyla-1 Predicted to enable dynein heavy chain binding activity. Predicted to be located in axoneme and filopodium. Expressed in OLQDL; OLQDR; OLQVL; OLQVR; and head neurons. Human ortholog(s) of this gene implicated in spermatogenic failure. Is an ortholog of human DNALI1 (dynein axonemal light intermediate chain 1). WB:WBGene00018309 F41G4.5 Is affected by several genes including daf-2; glp-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00018310 F41G4.7 Enriched in ABplpaappa; ABprpaappa; and outer labial neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including allantoin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018311 F41G4.8 Enriched in several structures, including GLR; coelomocyte; germ line; head mesodermal cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018312 F41H8.1 Predicted to be located in membrane. WB:WBGene00018313 F41H8.2 Predicted to be located in membrane. WB:WBGene00018314 F41H10.1 Predicted to be located in membrane. WB:WBGene00018315 F41H10.2 Enriched in ASIL; ASIR; muscle cell; neurons; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00018316 F41H10.3 Predicted to enable RNA-dependent RNA polymerase activity. Predicted to be involved in RNA-templated transcription. WB:WBGene00018317 F41H10.4 Predicted to be involved in neurotransmitter receptor transport, endosome to postsynaptic membrane; regulation of intracellular transport; and regulation of modification of synaptic structure. Predicted to be located in glutamatergic synapse and postsynaptic recycling endosome. Predicted to be extrinsic component of postsynaptic early endosome membrane. Is an ortholog of human GRIPAP1 (GRIP1 associated protein 1). WB:WBGene00018318 F41H10.5 Predicted to be involved in membrane organization and phospholipid homeostasis. Predicted to be located in plasma membrane. Is an ortholog of human TLCD1 (TLC domain containing 1) and TLCD2 (TLC domain containing 2). WB:WBGene00018319 hda-6 Predicted to enable histone deacetylase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of histone deacetylase complex. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in several diseases, including cervix uteri carcinoma in situ; chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia; and polycystic liver disease. Is an ortholog of human HDAC6 (histone deacetylase 6). WB:WBGene00018321 sand-1 Involved in several processes, including body morphogenesis; regulation of cellular localization; and vesicle-mediated transport. Located in early endosome and membrane. Is an ortholog of human MON1B (MON1 homolog B, secretory trafficking associated). WB:WBGene00018322 F41H10.12 Enriched in PLM and anterior arcade cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; nhr-49; and aak-2 based on microarray and RNA-seq studies. Is affected by Cholestanol; resveratrol; and dafa#1 based on microarray studies. WB:WBGene00018323 F42A6.1 Predicted to be located in membrane. WB:WBGene00018324 F42A6.2 Enriched in male based on RNA-seq studies. Is affected by several genes including let-60; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018325 F42A6.3 Enriched in germ line based on proteomic studies. Is affected by several genes including daf-16; hsf-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by cadmium and Atrazine based on RNA-seq and microarray studies. WB:WBGene00018326 cyp-25A5 Enriched in OLL; PVD; and sensory neurons based on microarray and RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on RNA-seq; proteomic; and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; Sodium Chloride; and Rifampin based on RNA-seq studies. WB:WBGene00018327 F42A6.5 Predicted to be involved in DNA repair. Predicted to be located in cellular anatomical entity. WB:WBGene00018328 F42A6.6 Predicted to enable Hsp70 protein binding activity and nuclear import signal receptor activity. Predicted to be involved in protein import into nucleus. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 13. Is an ortholog of human HIKESHI (heat shock protein nuclear import factor hikeshi). WB:WBGene00018329 fbxa-130 Is affected by several genes including let-60; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018330 elks-1 Enables PDZ domain binding activity. Involved in protein localization and regulation of protein deneddylation. Located in basement membrane and presynaptic active zone. Expressed in nervous system. Is an ortholog of human ERC2 (ELKS/RAB6-interacting/CAST family member 2). WB:WBGene00018332 F42A9.3 Predicted to be located in membrane. WB:WBGene00018333 cyp-33E3 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. WB:WBGene00018334 cyp-33E2 Enables monooxygenase activity. Involved in long-chain fatty acid metabolic process and regulation of pharyngeal pumping. Located in intracellular membrane-bounded organelle. Expressed in pharynx. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00018335 F42A9.6 Predicted to be located in membrane. WB:WBGene00018336 F42A9.7 Predicted to be located in cytoskeleton. WB:WBGene00018337 F42A9.8 Enriched in Y cell; coelomocyte; germ line; neurons; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including hydrogen sulfide; rotenone; and metformin based on microarray and RNA-seq studies. WB:WBGene00018338 F42A9.9 Predicted to be located in membrane. WB:WBGene00018339 abcf-3 Predicted to enable ATP binding activity. Involved in positive regulation of peptidyl-serine phosphorylation; regulation of apoptotic process; and regulation of translation. Predicted to be located in cytosolic ribosome. Expressed in several structures, including body wall musculature; head neurons; hermaphrodite gonad; intestinal cell; and pharyngeal neurons. Is an ortholog of human ABCF3 (ATP binding cassette subfamily F member 3). WB:WBGene00018340 anmt-2 Predicted to enable N-methyltransferase activity. Predicted to be located in cytosol. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; hypertension; multiple sclerosis; and renal cell carcinoma. Is an ortholog of human INMT (indolethylamine N-methyltransferase). WB:WBGene00018341 F42A10.5 Predicted to be located in cytoplasm. Expressed in head neurons; intestine; nerve ring; spermatheca; and tail. WB:WBGene00018342 F42A10.6 Enriched in ABplpppppp; ABprpppppp; mechanosensory neurons; and somatic gonad precursor based on SAGE; Chronogram; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-five chemicals including Ethanol; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. WB:WBGene00018343 F42A10.7 Enriched in ASER and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-nine chemicals including methylmercury hydroxide; methylmercuric chloride; and Mercuric Chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00018344 npr-27 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00018345 F42C5.3 Enriched in several structures, including AFD; germ line; male distal tip cell; neuronal sheath cell; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Nitric Oxide; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. WB:WBGene00018346 F42C5.4 Predicted to enable metal ion binding activity. WB:WBGene00018347 F42C5.5 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00018348 F42C5.6 Predicted to be located in membrane. WB:WBGene00018349 F42C5.9 Located in plasma membrane and striated muscle dense body. WB:WBGene00018350 ifo-1 Enriched in head mesodermal cell; intestine; pharyngeal muscle cell; and sensory neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by nineteen chemicals including hydrogen sulfide; rotenone; and D-glucose based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018351 F42G2.2 Enriched in several structures, including ABalppppaa; ABalpppppa; ABalppppppa; ABalppppppp; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Heme; D-glucopyranose; and sesamin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00018352 fbxc-20 Enriched in several structures, including ABalpppappp; ABalppppaa; PVP; amphid neurons; and lateral ganglion based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including aldicarb; 1-methylnicotinamide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00018353 fbxa-182 Enriched in RICL; RICR; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; methylmercuric chloride; and D-glucopyranose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00018354 F42G2.5 Predicted to enable FFAT motif binding activity. Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum-plasma membrane tethering. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 8 and autosomal dominant adult-onset proximal spinal muscular atrophy. Is an ortholog of human VAPA (VAMP associated protein A) and VAPB (VAMP associated protein B and C). WB:WBGene00018355 ceh-86 Predicted to enable DNA binding activity. Predicted to be involved in autophagy. Predicted to be located in nucleus. WB:WBGene00018356 islo-1 Predicted to be located in membrane. Expressed in body wall musculature and non-striated muscle. WB:WBGene00018357 moc-3 Predicted to enable URM1 activating enzyme activity; nucleotidyltransferase activity; and thiosulfate sulfurtransferase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process; protein urmylation; and tRNA wobble position uridine thiolation. Predicted to be located in cytosol. Is an ortholog of human MOCS3 (molybdenum cofactor synthesis 3). WB:WBGene00018358 erp-44.3 Predicted to enable protein disulfide isomerase activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment. Is an ortholog of human ERP44 (endoplasmic reticulum protein 44). WB:WBGene00018359 F42G8.8 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00018360 irld-8 Predicted to be located in membrane. WB:WBGene00018361 ndub-11 Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 3 and nuclear type mitochondrial complex I deficiency 30. Is an ortholog of human NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11). WB:WBGene00018362 ppm-1.G Predicted to enable metal ion binding activity and myosin phosphatase activity. Expressed in gonad and head. Is an ortholog of human PPM1G (protein phosphatase, Mg2+/Mn2+ dependent 1G). WB:WBGene00018363 nlp-52 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00018364 dagl-2 Predicted to enable triglyceride lipase activity. Predicted to be involved in cellular lipid metabolic process; neurogenesis; and neurotransmitter biosynthetic process. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in lung cancer. Is an ortholog of human DAGLB (diacylglycerol lipase beta). WB:WBGene00018365 tpst-2 Predicted to enable protein-tyrosine sulfotransferase activity. Predicted to be located in Golgi apparatus. WB:WBGene00018366 F42H10.2 Predicted to enable protein-disulfide reductase activity. Predicted to be involved in protein import into mitochondrial intermembrane space and protein maturation by protein folding. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human CHCHD4 (coiled-coil-helix-coiled-coil-helix domain containing 4). WB:WBGene00018367 F42H10.3 Predicted to enable actin filament binding activity. Located in cell junction and striated muscle dense body. Is an ortholog of human LASP1 (LIM and SH3 protein 1). WB:WBGene00018369 mig-39 Predicted to enable metal ion binding activity and protein dimerization activity. Acts upstream of or within with a positive effect on negative regulation of distal tip cell migration. Located in cytoplasm and nucleus. Expressed in distal tip cell and germ line. WB:WBGene00018370 F42H10.6 Enables identical protein binding activity. Is an ortholog of human ACOT13 (acyl-CoA thioesterase 13). WB:WBGene00018371 ess-2 Located in nucleus. Expressed in several structures, including body wall musculature; neurons; pharynx; and seam cell. Used to study DiGeorge syndrome and velocardiofacial syndrome. Is an ortholog of human ESS2 (ess-2 splicing factor homolog). WB:WBGene00018373 F43B10.1 Predicted to enable protein phosphatase regulator activity. Predicted to be part of protein phosphatase type 2A complex. Is an ortholog of human PPP2R3A (protein phosphatase 2 regulatory subunit B''alpha) and PPP2R3B (protein phosphatase 2 regulatory subunit B''beta). WB:WBGene00018374 tag-343 Predicted to be located in membrane. WB:WBGene00018375 F43C9.1 Enriched in PVT and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; tryptophan; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily and F-box domain. WB:WBGene00018376 F43C9.2 Predicted to enable calcium ion binding activity and enzyme regulator activity. Human ortholog(s) of this gene implicated in congenital myopathy 15. Is an ortholog of human TNNC2 (troponin C2, fast skeletal type). WB:WBGene00018377 hum-10 Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be located in actin cytoskeleton; cytoplasm; and vesicle. Predicted to be part of myosin complex. WB:WBGene00018378 F43C11.1 Enriched in PVD; germ line; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00018379 F43C11.2 Enriched in NSM; germ line; male-specific anatomical entity; and in male based on proteomic; tiling array; RNA-seq; and microarray studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00018380 F43C11.3 Enriched in germ line and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on quantitative PCR; microarray; and RNA-seq studies. Is affected by twenty-six chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00018381 F43C11.4 Is affected by several genes including sir-2.1; clk-1; and mdt-15 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00018382 F43C11.5 Is affected by several genes including daf-12; clk-1; and smg-2 based on microarray; tiling array; and RNA-seq studies. WB:WBGene00018383 F43C11.6 Predicted to be located in membrane. WB:WBGene00018384 F43C11.7 Predicted to enable zinc ion binding activity. Involved in defense response to Gram-positive bacterium and determination of adult lifespan. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; Sweet syndrome; and hematologic cancer (multiple). Is an ortholog of several human genes including MEFV (MEFV innate immunity regulator, pyrin); TRIM21 (tripartite motif containing 21); and TRIM27 (tripartite motif containing 27). WB:WBGene00018385 F43C11.8 Predicted to enable zinc ion binding activity. Is an ortholog of human TRIM13 (tripartite motif containing 13) and TRIM59 (tripartite motif containing 59). WB:WBGene00018386 enri-1 Enriched in AFD; germ line; and hypodermis based on RNA-seq studies. Is affected by several genes including dpy-10; daf-12; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018387 F43C11.10 Enriched in several structures, including ABaraapapp; ABaraapppp; ABplpppaaa; ABprpppaaa; and pharyngeal cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mir-35 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Ag nanoparticles based on RNA-seq studies. WB:WBGene00018388 F43C11.11 Enriched in ALM; BDU; and rectal epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and alg-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00018389 F43C11.12 Enriched in AVE; NSM; and in male based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00018390 F43E2.1 Predicted to be involved in mRNA polyadenylation. WB:WBGene00018391 rpb-4 Predicted to enable translation initiation factor binding activity. Predicted to be involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex and transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II, core complex. Is an ortholog of human POLR2D (RNA polymerase II subunit D). WB:WBGene00018392 insc-1 Predicted to enable cytoskeletal anchor activity. Predicted to be involved in apical protein localization; establishment of mitotic spindle orientation; and regulation of asymmetric cell division. Predicted to be located in apical cortex. Expressed in several structures, including body wall musculature; hypodermis; and pharynx. Is an ortholog of human INSC (INSC spindle orientation adaptor protein). WB:WBGene00018393 msra-1 Enables L-methionine:thioredoxin-disulfide S-oxidoreductase activity and peptide-methionine (S)-S-oxide reductase activity. Involved in obsolete oxidation-reduction process. Predicted to be located in cytoplasm. Expressed in hypodermis and neurons. Is an ortholog of human MSRA (methionine sulfoxide reductase A). WB:WBGene00018394 F43E2.6 Enriched in germ line; muscle cell; neurons; retrovesicular ganglion; and ventral nerve cord based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including Tunicamycin; manganese chloride; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00018395 mtch-1 Predicted to be located in membrane. Is an ortholog of human MTCH1 (mitochondrial carrier 1) and MTCH2 (mitochondrial carrier 2). WB:WBGene00018397 F43E2.11 Predicted to enable isomerase activity. Is an ortholog of human MTCH1 (mitochondrial carrier 1) and MTCH2 (mitochondrial carrier 2). WB:WBGene00018398 sptl-2 Predicted to enable serine C-palmitoyltransferase activity. Predicted to be involved in ceramide biosynthetic process and sphingosine biosynthetic process. Predicted to be part of serine C-palmitoyltransferase complex. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1C. Is an ortholog of human SPTLC2 (serine palmitoyltransferase long chain base subunit 2) and SPTLC3 (serine palmitoyltransferase long chain base subunit 3). WB:WBGene00018399 F43H9.3 Predicted to enable RNA uridylyltransferase activity. WB:WBGene00018400 F43H9.4 Predicted to enable N-acyltransferase activity. Predicted to be located in mitochondrion. Is an ortholog of several human genes including GLYAT (glycine-N-acyltransferase); GLYATL1 (glycine-N-acyltransferase like 1); and GLYATL2 (glycine-N-acyltransferase like 2). WB:WBGene00018402 kvs-3 Predicted to enable delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Expressed in AVAL; AVAR; and nervous system. Is an ortholog of human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1). WB:WBGene00018403 F44A2.3 Predicted to enable lipid binding activity. Predicted to be located in extracellular space. Expressed in amphid socket cell; excretory duct; head; hypodermis; and vulva. Is an ortholog of human BPIFC (BPI fold containing family C). WB:WBGene00018404 nhr-39 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00018405 F44A2.5 Predicted to enable translation activator activity. Predicted to be involved in regulation of translational initiation. Located in sarcoplasmic reticulum. Expressed in metacorpus and procorpus. Is an ortholog of human MIF4GD (MIF4G domain containing). WB:WBGene00018406 F44A2.7 Enriched in ASER and AVK based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; multi-walled carbon nanotube; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: YitH/HolE, acetyltransferase (GNAT) domain; Protein of unknown function (DUF1248); Domain of unknown function DUF1248; Acyl-CoA N-acyltransferase; and Acetyltransferase (GNAT) domain. WB:WBGene00018407 F44B9.2 Expressed in body wall musculature and vulval muscle. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018408 F44B9.5 Predicted to enable acyltransferase activity and ubiquitin binding activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be located in membrane. Expressed in vulA; vulB1; and vulB2. Is an ortholog of human AUP1 (AUP1 lipid droplet regulating VLDL assembly factor). WB:WBGene00018409 F44B9.8 Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA binding activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in DNA repair and DNA-templated DNA replication. Predicted to be located in nucleus. Predicted to be part of DNA replication factor C complex. Is an ortholog of human RFC5 (replication factor C subunit 5). WB:WBGene00018410 F44B9.9 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00018411 F44B9.10 Predicted to enable calcium ion binding activity and phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion; lipid catabolic process; and phospholipid metabolic process. Predicted to be located in extracellular region. Is an ortholog of human PLA2G12A (phospholipase A2 group XIIA) and PLA2G12B (phospholipase A2 group XIIB). WB:WBGene00018412 nhr-37 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in neurons and seam cell. WB:WBGene00018413 cyp-33C4 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). WB:WBGene00018414 nstp-8 Predicted to enable UDP-galactose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport and carbohydrate transport. Predicted to be located in Golgi membrane. WB:WBGene00018415 nhr-184 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00018416 cerv-1 No description available WB:WBGene00018417 F44E2.3 Predicted to be located in mitochondrion and nucleoplasm. Is an ortholog of human ARGLU1 (arginine and glutamate rich 1). WB:WBGene00018418 F44E2.4 Predicted to be located in membrane. WB:WBGene00018419 F44E2.6 Predicted to enable peptide-methionine (R)-S-oxide reductase activity. Predicted to be involved in protein repair and response to oxidative stress. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 74. Is an ortholog of human MSRB2 (methionine sulfoxide reductase B2). WB:WBGene00018420 F44E2.7 Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. WB:WBGene00018421 F44E2.8 Enriched in NSM and germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including bisphenol S; Alovudine; and stavudine based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: YbiA-like superfamily; NADAR domain; NADAR; and Phosphorylation site. WB:WBGene00018422 F44E2.9 Enriched in several structures, including body wall muscle cell; germ line; intestine; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018423 F44E2.10 Predicted to enable carbohydrate binding activity. Predicted to be located in membrane. Is an ortholog of human MLEC (malectin). WB:WBGene00018424 pgph-2 Predicted to enable phosphatase activity. Predicted to be located in cytoplasm. Is an ortholog of human PDXP (pyridoxal phosphatase) and PGP (phosphoglycolate phosphatase). WB:WBGene00018425 F44E7.3 Enriched in intestine; somatic gonad precursor; and in male based on RNA-seq and microarray studies. Is affected by several genes including let-60; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including D-glucose; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018426 F44E7.4 Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis involved in protein catabolic process. Predicted to be located in cytosol and mitochondrion. Expressed in gonad. Human ortholog(s) of this gene implicated in Alzheimer's disease; diabetic encephalopathy; and type 2 diabetes mellitus. Is an ortholog of human IDE (insulin degrading enzyme). WB:WBGene00018427 F44E7.5 Enriched in germ line and germline precursor cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on proteomic; RNA-seq; and microarray studies. Is affected by twenty-four chemicals including manganese chloride; sodium arsenite; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00018428 fbxa-183 Enriched in GABAergic neurons and excretory cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pmk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and antimycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00018429 F44E7.7 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00018430 nhr-142 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00018431 F44E7.9 Predicted to be involved in mitochondrial respirasome assembly. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 2. Is an ortholog of human RAB5IF (RAB5 interacting factor). WB:WBGene00018432 irld-33 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00018433 ceh-82 Predicted to enable DNA binding activity. Expressed in neurons. WB:WBGene00018434 ceh-81 Predicted to enable DNA binding activity. Expressed in dorsal nerve cord; head; head muscle; tail neurons; and ventral nerve cord. WB:WBGene00018435 btb-9 Enriched in AFD; body wall muscle cell; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00018436 fbxb-11 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABplapppaa; amphid neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; stavudine; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00018437 btb-8 Predicted to be located in membrane. WB:WBGene00018438 btb-6 Enriched in several structures, including ABalaaaarl; ABalaaaarr; BAG; germ line; and muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including hydrogen sulfide; rotenone; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00018439 fbxa-184 Enriched in ABalppappa; ABarappppa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and lin-4 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00018440 F45C12.9 Enriched in AUAL; AUAR; AVHL; AVHR; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including csr-1; mex-3; and mex-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Atrazine based on microarray studies. WB:WBGene00018441 math-29 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00018442 sdz-18 Enriched in ABalaaaala; ABalaapaaa; ABalaapppa; ABalapaapa; and AIN based on single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including 1-methylnicotinamide; methylmercuric chloride; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily; BTB/POZ domain; MATH/TRAF domain; and MATH domain. WB:WBGene00018443 btb-7 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00018444 fbxb-48 Enriched in ABalaaaarl; ABalaaaarr; and body wall muscle cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; methylmercuric chloride; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00018445 fbxb-5 Enriched in ABplppppaa; ABprppppaa; MSpaaapa; and rect_D based on single-cell RNA-seq studies. Is affected by several genes including eat-2; tdc-1; and set-2 based on tiling array and RNA-seq studies. Is affected by eight chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00018446 ceh-83 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in hypodermis; intestine; and vulva. WB:WBGene00018447 irld-9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including lin-4; eat-2; and lin-14 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00018448 F45D11.1 Enriched in intestine; muscle cell; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; tryptophan; and 4-bromodiphenyl ether based on microarray and RNA-seq studies. WB:WBGene00018449 F45D11.2 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; skn-1; and pmk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including sesamin; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00018450 F45D11.3 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including sesamin; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00018451 F45D11.4 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including sesamin; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00018452 F45D11.5 Enriched in several structures, including ABalpppapa; ABarpapaaa; amphid neurons; cephalic sheath cell; and pharyngeal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00018453 F45D11.6 No description available WB:WBGene00018454 fbxb-28 Is affected by several genes including eat-2; daf-1; and mex-3 based on tiling array and RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00018455 fbxc-42 Enriched in several structures, including ABprpapppa; Z1.p; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including bisphenol A; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00018456 fbxc-39 Enriched in several structures, including ABalppppaa; ABplpaappa; ABplpapapa; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including methylmercuric chloride; multi-walled carbon nanotube; and bisphenol S based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00018457 fbxb-29 Enriched in ABarpapaapp; ABplaaaaapp; MC neuron; MCL; and MCR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and cyc-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00018458 fbxb-30 Enriched in MSaapaapa; MSpapaapa; g2L; and g2R based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and bisphenol S based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00018459 F45D11.14 Expressed in hypodermis and intestine. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF684); Protein of unknown function DUF684; and Phosphorylation site. WB:WBGene00018460 F45D11.15 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; RNA-seq; and microarray studies. Is affected by fifteen chemicals including Ethanol; Tunicamycin; and sesamin based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF684); Protein of unknown function DUF684; and Phosphorylation site. WB:WBGene00018461 F45D11.16 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; RNA-seq; and microarray studies. Is affected by sixteen chemicals including Ethanol; sesamin; and stavudine based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF684); Protein of unknown function DUF684; and Phosphorylation site. WB:WBGene00018462 F45E1.1 Enriched in neurons and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; sek-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00018463 F45E1.2 Enriched in neurons and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including lin-39; daf-3; and mex-3 based on RNA-seq; tiling array; and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018465 F45E1.4 Predicted to enable phosphoglycolate phosphatase activity. Predicted to be involved in DNA repair and dephosphorylation. WB:WBGene00018466 F45E1.5 Enriched in AFD; intestine; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on RNA-seq and microarray studies. Is affected by six chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00018467 sdpn-1 Predicted to enable phospholipid binding activity. Involved in endocytic recycling. Located in early endosome and recycling endosome membrane. Expressed in intestine; pharyngeal muscle cell; and pharynx. Used to study Huntington's disease. Is an ortholog of human PACSIN1 (protein kinase C and casein kinase substrate in neurons 1); PACSIN2 (protein kinase C and casein kinase substrate in neurons 2); and PACSIN3 (protein kinase C and casein kinase substrate in neurons 3). WB:WBGene00018468 cla-1 Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Involved in maintenance of presynaptic active zone structure; spontaneous synaptic transmission; and synaptic vesicle cycle. Located in presynaptic active zone. Expressed in nervous system. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 3. Is an ortholog of human BSN (bassoon presynaptic cytomatrix protein) and PCLO (piccolo presynaptic cytomatrix protein). WB:WBGene00018470 F45E4.5 Involved in defense response to Gram-negative bacterium. WB:WBGene00018471 F45E4.6 Predicted to be located in membrane. WB:WBGene00018472 nep-16 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00018473 cima-1 Predicted to enable sialic acid transmembrane transporter activity. Involved in regulation of protein catabolic process and regulation of synapse organization. Located in lysosome. Expressed in hypodermis and intestine. WB:WBGene00018474 cnep-1 Predicted to enable protein serine/threonine phosphatase activity. Involved in nuclear membrane reassembly and regulation of nuclear division. Located in nuclear envelope. Is an ortholog of human CTDNEP1 (CTD nuclear envelope phosphatase 1). WB:WBGene00018475 F45E12.5 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human C1orf53 (chromosome 1 open reading frame 53). WB:WBGene00018476 F45E12.6 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00018477 otpl-4 Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. WB:WBGene00018478 otpl-5 Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1); OTOP2 (otopetrin 2); and OTOP3 (otopetrin 3). WB:WBGene00018479 otpl-6 Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1); OTOP2 (otopetrin 2); and OTOP3 (otopetrin 3). WB:WBGene00018480 otpl-7 Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1). WB:WBGene00018481 F45F2.9 Predicted to enable 5'-deoxynucleotidase activity. Is an ortholog of human HDDC2 (HD domain containing 2). WB:WBGene00018482 F45F2.10 Enriched in several structures, including MSaaaaapa; germ line; germline precursor cell; intestine; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; daf-12; and hsf-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by fourteen chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Ankyrin repeat-containing domain superfamily. WB:WBGene00018483 F45F2.11 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00018484 F46C8.1 Predicted to be located in membrane. WB:WBGene00018485 F46C8.3 Predicted to be located in membrane. WB:WBGene00018486 glb-16 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in head neurons and tail neurons. WB:WBGene00018487 F46C8.8 Enriched in several structures, including MSaapapa; MSpapapa; amphid socket cell; sensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including hydrogen sulfide; Ethanol; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00018488 acs-1 Predicted to enable medium-chain fatty acid-CoA ligase activity. Involved in establishment or maintenance of epithelial cell apical/basal polarity. Expressed in gonad; intestine; neurons; and seam cell. Is an ortholog of human ACSF2 (acyl-CoA synthetase family member 2). WB:WBGene00018489 F46E10.2 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; rectal epithelial cell; and rectum based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00018490 F46E10.3 Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00018491 mdh-1 Enables L-malate dehydrogenase activity. Involved in malate metabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 88. Is an ortholog of human MDH1 (malate dehydrogenase 1). WB:WBGene00018492 hpo-26 Enriched in AFD; PLM; and arcade cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by twenty chemicals including Heme; 1-methylnicotinamide; and Mercuric Chloride based on microarray and RNA-seq studies. WB:WBGene00018493 F46F5.1 Enriched in AFD and in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; Doxycycline; and paraquat based on microarray and RNA-seq studies. WB:WBGene00018494 F46F5.2 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including glycine; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00018495 F46F5.4 Enriched in male based on RNA-seq studies. Is affected by several genes including sir-2.1; aak-2; and bar-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Tunicamycin; Doxycycline; and paraquat based on microarray and RNA-seq studies. WB:WBGene00018496 F46F5.5 Predicted to enable ATP-dependent peptidase activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00018497 msrp-3 Enriched in amphid sheath cell and germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including aldicarb; hydrogen sulfide; and Ethanol based on microarray and RNA-seq studies. WB:WBGene00018498 F46F5.7 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00018499 F46F5.8 Is affected by several genes including rrf-3; clk-1; and rrf-1 based on tiling array and microarray studies. Is affected by Tunicamycin and paraquat based on microarray studies. WB:WBGene00018500 msrp-4 Enriched in body wall muscle cell and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including multi-walled carbon nanotube; D-glucose; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00018501 F46F5.10 Predicted to be located in membrane. WB:WBGene00018502 F46F5.11 Predicted to be located in membrane. WB:WBGene00018503 F46F5.12 Is affected by hpl-2; rsr-2; and ain-1 based on tiling array and microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies. WB:WBGene00018504 F46F5.13 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00018505 F46F5.14 Predicted to be located in membrane. WB:WBGene00018506 F46F5.15 Enriched in pm8 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride and Colistin based on microarray studies. WB:WBGene00018507 F46F5.16 Predicted to be located in membrane. WB:WBGene00018508 F46F11.1 Predicted to enable ATP binding activity; diphosphoinositol-pentakisphosphate kinase activity; and phosphotransferase activity, phosphate group as acceptor. Predicted to be involved in inositol metabolic process and inositol phosphate biosynthetic process. Located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 100. Is an ortholog of human PPIP5K2 (diphosphoinositol pentakisphosphate kinase 2). WB:WBGene00018509 xrep-4 Expressed in intestine; muscle cell; neurons; and pharynx. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00018510 F46F11.7 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and pmk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00018511 F46F11.8 Enriched in OLL; body wall muscle cell; germ line; germline precursor cell; and interneuron based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and aak-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018512 trpp-8 Predicted to be part of TRAPPIII protein complex. Is an ortholog of human TRAPPC8 (trafficking protein particle complex subunit 8). WB:WBGene00018513 trmt-10C.1 Predicted to enable tRNA (guanine-N1-)-methyltransferase activity and tRNA binding activity. Predicted to be involved in mitochondrial tRNA 5'-end processing and positive regulation of mitochondrial translation. Predicted to be located in mitochondrion and nucleoplasm. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 30. Is an ortholog of human TRMT10C (tRNA methyltransferase 10C, mitochondrial RNase P subunit). WB:WBGene00018514 twnk-1 Predicted to enable 5'-3' DNA helicase activity and single-stranded DNA binding activity. Predicted to be involved in mitochondrial DNA replication. Predicted to be located in mitochondrial nucleoid. Human ortholog(s) of this gene implicated in Perrault syndrome; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 3; and mitochondrial DNA depletion syndrome 7. Is an ortholog of human TWNK (twinkle mtDNA helicase). WB:WBGene00018515 F46G11.2 Enriched in several structures, including AFD; CEP socket cell; anterior hypodermis; excretory cell; and neuronal sheath cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018516 gakh-1 Predicted to enable AP-2 adaptor complex binding activity and protein serine/threonine kinase activity. Predicted to be involved in positive regulation of Notch signaling pathway and regulation of clathrin-dependent endocytosis. Predicted to be located in cytoplasm. Expressed in intestine; neurons; and pharynx. Is an ortholog of human GAK (cyclin G associated kinase). WB:WBGene00018517 F46G11.4 Enriched in several structures, including ABplapaaapa; head mesodermal cell; muscle cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including D-glucose; sesamin; and stavudine based on RNA-seq and microarray studies. WB:WBGene00018518 F46H5.2 Predicted to enable kinase activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be involved in phosphorylation. Is an ortholog of human PABIR1 (PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1). WB:WBGene00018519 F46H5.3 Predicted to enable kinase activity. Predicted to be involved in phosphocreatine biosynthetic process and phosphorylation. Is an ortholog of several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1B (creatine kinase, mitochondrial 1B). WB:WBGene00018520 F46H5.4 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Predicted to be located in cellular anatomical entity. Human ortholog(s) of this gene implicated in several diseases, including Adams-Oliver syndrome; developmental and epileptic encephalopathy 23; and gastrointestinal system cancer (multiple). Is an ortholog of human DOCK8 (dedicator of cytokinesis 8). WB:WBGene00018521 F46H5.5 Enriched in several structures, including ABplaapappp; ABplapppapp; ABpraapappp; head mesodermal cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including stavudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018522 F46H5.7 Predicted to enable protein kinase binding activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleotide-activated protein kinase complex. WB:WBGene00018523 lact-1 Enriched in several structures, including head ganglion; head mesodermal cell; muscle cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including Tunicamycin; D-glucose; and juglone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Beta-lactamase; Beta-lactamase/transpeptidase-like; and Beta-lactamase-related. WB:WBGene00018525 F47B3.1 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00018526 F47B3.2 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00018527 F47B3.3 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human PLLP (plasmolipin). WB:WBGene00018528 F47B3.4 Predicted to be located in membrane. WB:WBGene00018529 F47B3.5 Enriched in ALM; PLM; and germ line based on proteomic; microarray; and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by Cry5B and silicon dioxide nanoparticle based on microarray studies. Is predicted to encode a protein with the following domain: DUF236 repeat. WB:WBGene00018530 F47B3.6 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00018531 F47B3.7 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00018532 pmpl-1 Predicted to be located in membrane. Expressed in several structures, including hypodermis; vulva; and vulval precursor cell. WB:WBGene00018533 F47B7.2 Predicted to enable flavin-dependent sulfhydryl oxidase activity and protein disulfide isomerase activity. Predicted to be involved in protein folding. Predicted to be located in extracellular space. Expressed in head. Is an ortholog of human QSOX1 (quiescin sulfhydryl oxidase 1) and QSOX2 (quiescin sulfhydryl oxidase 2). WB:WBGene00018534 F47B7.3 Is affected by several genes including pmk-1; clk-1; and mdt-15 based on tiling array; microarray; and RNA-seq studies. Is affected by resveratrol; Atrazine; and nitroguanidine based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00018535 F47B7.4 Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by glycine and nitroguanidine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00018536 F47B7.5 Enriched in DA neuron and VA neuron based on tiling array studies. Is affected by several genes including age-1; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00018537 F47B7.6 Enriched in AFD; NSM; muscle cell; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018538 marg-1 Expressed in marginal cell. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018539 nhr-185 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00018540 btb-21 Enriched in OLL; PVD; and intestine based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Heme; Tunicamycin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00018541 nhr-186 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00018542 nhr-187 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in dorsal nerve cord; head muscle; and head neurons. WB:WBGene00018543 ugt-32 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00018544 nhr-188 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons and tail neurons. WB:WBGene00018545 nhr-189 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00018547 clec-78 Predicted to enable calcium ion binding activity and serine-type peptidase activity. Involved in defense response to Gram-positive bacterium. Predicted to be located in membrane. Expressed in pharyngeal muscle cell. WB:WBGene00018548 clec-79 Enriched in germ line; hypodermis; and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-four chemicals including hydrogen sulfide; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00018549 F47C12.6 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including clk-1; csr-1; and mex-1 based on microarray and RNA-seq studies. Is affected by allantoin based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00018550 F47C12.7 Enriched in NSM; body wall muscle cell; germ line; male-specific anatomical entity; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including eat-2; tph-1; and csr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Tunicamycin and Atrazine based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00018551 F47C12.8 Enriched in AVK; neurons; and in male based on RNA-seq studies. Is affected by several genes including clk-1; aak-2; and lin-15B based on microarray and RNA-seq studies. Is affected by methylmercuric chloride; Tunicamycin; and Atrazine based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00018552 srt-19 Predicted to be located in membrane. WB:WBGene00018553 srt-60 Is affected by clk-1 and eat-2 based on microarray studies. WB:WBGene00018554 srt-3 Predicted to be located in membrane. WB:WBGene00018555 srt-35 Predicted to be located in membrane. WB:WBGene00018556 srt-36 Predicted to be located in membrane. Expressed in ASIL and ASIR. WB:WBGene00018557 srt-38 Predicted to be located in membrane. WB:WBGene00018558 srt-20 Predicted to be located in membrane. Expressed in ASIL; ASIR; ASJL; and ASJR. WB:WBGene00018559 srt-37 Predicted to be located in membrane. WB:WBGene00018560 F47D12.3 Predicted to be involved in protein homooligomerization. WB:WBGene00018561 gadr-3 Predicted to be located in membrane. Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00018562 F47D12.6 Expressed in nerve ring. WB:WBGene00018563 F47D12.7 Enriched in several structures, including AVK; amphid sheath cell; anterior ganglion (post); germ line; and hyp3 based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-one chemicals including Heme; Ethanol; and nicotinic acid based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in spermatogenic failure 11. Is predicted to encode a protein with the following domains: Galactose oxidase, central domain; BTB/POZ domain; BTB And C-terminal Kelch; Kelch-type beta propeller; BTB-kelch protein; Kelch motif; BTB/Kelch-associated; SKP1/BTB/POZ domain superfamily; and Kelch repeat type 1. Is an ortholog of human KLHL10 (kelch like family member 10). WB:WBGene00018564 F47D12.9 Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Is an ortholog of human DCAF4 (DDB1 and CUL4 associated factor 4); DCAF4L1 (DDB1 and CUL4 associated factor 4 like 1); and DCAF4L2 (DDB1 and CUL4 associated factor 4 like 2). WB:WBGene00018565 F47E1.1 Enriched in XXX cell and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018566 F47E1.2 Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including breast ductal carcinoma; gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of human SLCO3A1 (solute carrier organic anion transporter family member 3A1). WB:WBGene00018567 prdm-14 Enriched in anterior hypodermis; arcade cell; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and sek-1 based on RNA-seq and microarray studies. Is affected by aldicarb based on microarray studies. WB:WBGene00018568 F47E1.4 Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including breast ductal carcinoma; gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of human SLCO3A1 (solute carrier organic anion transporter family member 3A1). WB:WBGene00018569 F47F2.1 Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in phosphorylation. Located in cytoplasm. Is an ortholog of human PRKX (protein kinase cAMP-dependent X-linked catalytic subunit). WB:WBGene00018571 F47F2.3 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018572 lin-42 Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of dauer larval development; negative regulation of miRNA transcription; and regulation of development, heterochronic. Located in cytoplasm and nucleus. Expressed in head; hyp7 syncytium; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome 1. Is an ortholog of human PER1 (period circadian regulator 1) and PER2 (period circadian regulator 2). WB:WBGene00018573 oac-30 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00018575 clec-119 Enriched in several structures, including PVP; Z1.p; amphid sheath cell; germ line; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by fifteen chemicals including hydrogen sulfide; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: C-type lectin fold. WB:WBGene00018576 F47G3.1 Predicted to enable metal ion binding activity. Predicted to be involved in superoxide metabolic process. WB:WBGene00018577 asna-2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and dcr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including rotenone; Zidovudine; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00018578 F47G3.3 Enriched in several structures, including ABalaapppa; ABalapaapa; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018579 acs-16 Predicted to enable medium-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty acid metabolic process. WB:WBGene00018580 F47G6.3 Predicted to be located in membrane. WB:WBGene00018582 F48A9.2 Enriched in head mesodermal cell; intestine; neurons; pharynx; and seam cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including Mercuric Chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018585 F48A11.4 Enriched in several structures, including ABalapaaaa; ABalappapa; ASER; germ line; and male distal tip cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including rotenone; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00018586 ubxn-3 Enables K48-linked polyubiquitin modification-dependent protein binding activity. Involved in several processes, including developmental process involved in reproduction; positive regulation of mitotic cell cycle, embryonic; and regulation of protein localization to chromatin. Located in nucleus and perinuclear region of cytoplasm. Part of chromatin. Expressed in gonad; neurons; spermatheca; and spermatocyte. Is an ortholog of human FAF1 (Fas associated factor 1). WB:WBGene00018587 F48B9.1 Is affected by several genes including skn-1; sek-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including aldicarb; rotenone; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018589 F48B9.3 Predicted to be located in membrane. WB:WBGene00018590 pdf-2 Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; locomotory behavior; and parturition. Expressed in arcade cell; neurons; and rectum. WB:WBGene00018591 npax-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Expressed in head neurons; hypodermis; and vulF. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple) and diabetic ketoacidosis. Is an ortholog of human PAX4 (paired box 4). WB:WBGene00018592 F48B9.7 No description available WB:WBGene00018593 F48B9.8 Predicted to be located in membrane. Is an ortholog of human FAM8A1 (family with sequence similarity 8 member A1). WB:WBGene00018594 aman-3 Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Predicted to be located in Golgi membrane. WB:WBGene00018595 fbxa-145 Predicted to be located in membrane. WB:WBGene00018596 F48C1.3 Predicted to be located in membrane. WB:WBGene00018598 F48C1.5 Enriched in AFD; germ line; germline precursor cell; and intestine based on RNA-seq and microarray studies. Is affected by several genes including skn-1; dpy-10; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by ten chemicals including rotenone; manganese chloride; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00018599 F48C1.6 Predicted to be located in membrane. WB:WBGene00018600 F48C1.8 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018601 F48C1.9 Enriched in hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00018602 F48D6.4 Predicted to be located in ribosome. WB:WBGene00018603 F48E3.2 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00018604 uggt-1 Enables UDP-glucose:glycoprotein glucosyltransferase activity. Involved in IRE1-mediated unfolded protein response; protein N-linked glycosylation via asparagine; and regulation of nematode larval development. Predicted to be located in endoplasmic reticulum. Expressed in several structures, including anal depressor muscle; germ line; neurons; pharyngeal-intestinal valve; and rectal gland cell. Is an ortholog of human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1) and UGGT2 (UDP-glucose glycoprotein glucosyltransferase 2). WB:WBGene00018605 F48E3.4 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00018606 F48E3.6 Predicted to be located in membrane. WB:WBGene00018607 chts-1 Predicted to be involved in carbohydrate metabolic process. Located in endoplasmic reticulum. Expressed in AIYL; AIYR; and somatic cell. WB:WBGene00018608 F48E3.9 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapapapa; ABalapappaa; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and let-7 based on tiling array; proteomic; microarray; and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018609 F48E8.2 Predicted to be involved in positive regulation of cell population proliferation. Predicted to be located in nucleus. Is an ortholog of human EAPP (E2F associated phosphoprotein). WB:WBGene00018610 F48E8.3 Predicted to enable FMN binding activity and oxidoreductase activity. WB:WBGene00018611 F48E8.4 Predicted to be involved in retrograde protein transport, ER to cytosol and ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum lumen. Is an ortholog of human OS9 (OS9 endoplasmic reticulum lectin). WB:WBGene00018612 disl-2 Predicted to enable 3'-5'-RNA exonuclease activity. Involved in regulation of cell fate specification and regulation of development, heterochronic. Predicted to be located in P-body. Human ortholog(s) of this gene implicated in Perlman syndrome and nephroblastoma. Is an ortholog of human DIS3L2 (DIS3 like 3'-5' exoribonuclease 2). WB:WBGene00018613 skpt-1 Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); and uterine disease (multiple). Is an ortholog of human SKP2 (S-phase kinase associated protein 2). WB:WBGene00018614 pals-31 Enriched in several structures, including intestine; male distal tip cell; neurons; retrovesicular ganglion; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Tunicamycin; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00018615 F48G7.4 Enriched in several structures, including accessory cell; coelomocyte; excretory cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018616 F48G7.5 Enriched in head mesodermal cell and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-nine chemicals including Heme; 1-methylnicotinamide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00018617 srt-17 Predicted to be located in membrane. WB:WBGene00018618 F48G7.7 Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including sucrose; stearic acid; and single-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00018619 F48G7.8 Enriched in arcade cell and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including Heme; Tunicamycin; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00018620 F48G7.9 Predicted to enable ATP binding activity and protein serine/threonine kinase activity. WB:WBGene00018621 F48G7.10 Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Expressed in tail. WB:WBGene00018622 nhr-190 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00018623 F48G7.12 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00018624 F48G7.13 Enriched in intestine and neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00018625 prp-17 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 15. Is an ortholog of human CDC40 (cell division cycle 40). WB:WBGene00018626 F49D11.2 Enriched in neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including clk-1; alg-1; and let-418 based on microarray and RNA-seq studies. Is affected by four chemicals including Tunicamycin; multi-walled carbon nanotube; and Chlorpyrifos based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00018627 F49D11.3 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00018628 F49D11.4 Enriched in AVHL and AVHR based on single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and dpy-7 based on RNA-seq and microarray studies. Is affected by eight chemicals including Tunicamycin; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00018629 F49D11.5 No description available WB:WBGene00018630 F49D11.6 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00018631 F49D11.7 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; antimycin; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00018632 tag-296 Predicted to enable ceramide 1-phosphate binding activity and ceramide 1-phosphate transfer activity. Predicted to be involved in ceramide transport and intermembrane lipid transfer. Predicted to be located in cytosol. Is an ortholog of human CPTP (ceramide-1-phosphate transfer protein). WB:WBGene00018634 pigx-1 Predicted to be located in membrane. WB:WBGene00018635 nprl-2 Predicted to contribute to GTPase activator activity. Predicted to be involved in cellular response to amino acid starvation; negative regulation of TORC1 signaling; and positive regulation of autophagy. Predicted to be located in vacuolar membrane. Predicted to be part of GATOR1 complex. Human ortholog(s) of this gene implicated in focal epilepsy. Is an ortholog of human NPRL2 (NPR2 like, GATOR1 complex subunit). WB:WBGene00018636 oef-1 Expressed in P lineage cell; germ cell; and oocyte. WB:WBGene00018637 F49E8.6 Enriched in MSpppaaa; g1; germ line; head mesodermal cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including aldicarb; rotenone; and mianserin based on microarray and RNA-seq studies. WB:WBGene00018638 F49E8.7 Enriched in body wall muscle cell and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nine chemicals including stavudine; Zidovudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018639 tbc-16 Predicted to enable GTPase activator activity. Predicted to be located in early endosome. Is an ortholog of human TBC1D16 (TBC1 domain family member 16). WB:WBGene00018640 F49E10.2 Predicted to enable beta-carotene 15,15'-dioxygenase activity and carotenoid dioxygenase activity. Predicted to be involved in carotene catabolic process and retinal metabolic process. WB:WBGene00018641 F49E10.4 Predicted to be involved in mitochondrial protein catabolic process and mitophagy by induced vacuole formation. Predicted to be located in mitochondrial outer membrane. WB:WBGene00018643 drd-50 Involved in defense response to Gram-positive bacterium and innate immune response. WB:WBGene00018644 F49F1.3 Enriched in male based on RNA-seq studies. Is affected by several genes including rrf-3; sir-2.1; and cyc-1 based on microarray and RNA-seq studies. Is affected by aldicarb and tetrabromobisphenol A based on microarray studies. WB:WBGene00018645 F49F1.5 Enriched in OLL; PVD; head mesodermal cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty-one chemicals including Heme; hydrogen sulfide; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00018646 mul-1 Involved in response to gamma radiation. Expressed in intestinal cell. WB:WBGene00018647 F49F1.7 Enriched in ALN; accessory cell; arcade cell; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty-three chemicals including methylmercuric chloride; Mercuric Chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00018648 F49F1.8 Is affected by several genes including skn-1; glp-1; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including tryptophan; Alovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00018649 F49F1.9 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00018650 F49F1.10 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00018651 F49F1.11 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00018652 F49F1.12 Predicted to be located in membrane. WB:WBGene00018653 F49H12.2 Enriched in body wall muscle cell; coelomocyte; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including age-1; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00018654 F49H12.3 Predicted to be involved in protein homooligomerization. WB:WBGene00018655 F49H12.4 Predicted to be located in membrane. Expressed in AQR; PVDL; PVDR; head neurons; and tail neurons. WB:WBGene00018656 txdc-12.2 Predicted to enable oxidoreductase activity. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in breast cancer; pancreatic ductal adenocarcinoma; and pancreatic ductal carcinoma. Is an ortholog of human TXNDC12 (thioredoxin domain containing 12). WB:WBGene00018657 acl-4 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Located in endoplasmic reticulum. Is an ortholog of human GPAT3 (glycerol-3-phosphate acyltransferase 3). WB:WBGene00018658 bath-22 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including ced-3; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018659 F52C6.2 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. WB:WBGene00018660 F52C6.3 Enables identical protein binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. WB:WBGene00018661 F52C6.4 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to be part of cytosolic small ribosomal subunit. WB:WBGene00018662 math-30 Enriched in NSM based on tiling array studies. Is affected by several genes including eat-2; clk-1; and drh-3 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride and Sirolimus based on microarray studies. WB:WBGene00018663 math-31 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by Atrazine and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00018664 bath-11 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including ced-3; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018665 bath-4 Enriched in ABalaapppa; ABalapaapa; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00018666 bath-6 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including glp-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by four chemicals including rotenone; stavudine; and paraquat based on RNA-seq and microarray studies. WB:WBGene00018667 bath-7 Enriched in AFD; germ line; germline precursor cell; and head mesodermal cell based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; glp-1; and elt-2 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including aldicarb; rotenone; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00018668 bath-2 Enriched in germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including elt-2; sir-2.1; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00018669 F52C6.12 Enriched in arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and elt-2 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00018670 F52C6.13 Enriched in ABplpppaaa; ABprpppaaa; and Y cell based on single-cell RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018671 F52C6.14 Enriched in germ line and neurons based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and csr-1 based on RNA-seq studies. Is affected by eight chemicals including aldicarb; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00018672 sorf-2 Predicted to enable phosphatidylinositol 3-kinase regulator activity. Involved in organelle fusion and positive regulation of early endosome to late endosome transport. Located in early endosome and late endosome. Human ortholog(s) of this gene implicated in cerebellar ataxia, mental retardation and dysequlibrium syndrome and hydrocephalus. Is an ortholog of human WDR81 (WD repeat domain 81). WB:WBGene00018674 F52C9.3 Predicted to enable ATP-dependent diacylglycerol kinase activity; acylglycerol kinase activity; and ceramide kinase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in Sengers syndrome and cataract 38. Is an ortholog of human AGK (acylglycerol kinase). WB:WBGene00018675 F52C9.5 Enriched in accessory cell; anterior hypodermis; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including stavudine; Zidovudine; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00018676 F52C9.6 No description available WB:WBGene00018678 tdpo-1 Predicted to enable 3'-tyrosyl-DNA phosphodiesterase activity; double-stranded DNA binding activity; and single-stranded DNA binding activity. Predicted to be involved in DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 1 with axonal neuropathy. Is an ortholog of human TDP1 (tyrosyl-DNA phosphodiesterase 1). WB:WBGene00018679 F52C12.2 Predicted to enable 18S rRNA aminocarboxypropyltransferase activity and S-adenosyl-L-methionine binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in cytoplasm. Is an ortholog of human TSR3 (TSR3 ribosome maturation factor). WB:WBGene00018680 tsen-54 Predicted to enable endonuclease activity. Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to be part of tRNA-intron endonuclease complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2A; pontocerebellar hypoplasia type 4; and pontocerebellar hypoplasia type 5. Is an ortholog of human TSEN54 (tRNA splicing endonuclease subunit 54). WB:WBGene00018681 denn-4 Predicted to be involved in regulation of Rab protein signal transduction. Predicted to be located in cytoplasmic vesicle. Is an ortholog of human DENND4B (DENN domain containing 4B) and DENND4C (DENN domain containing 4C). WB:WBGene00018682 aagr-4 Predicted to enable alpha-glucosidase activity. Predicted to be involved in N-glycan processing. Human ortholog(s) of this gene implicated in polycystic kidney disease 3 and polycystic liver disease. Is an ortholog of human GANAB (glucosidase II alpha subunit) and GANC (glucosidase alpha, neutral C). WB:WBGene00018683 F52D1.2 Enriched in RIBL; RIBR; head mesodermal cell; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00018684 fbxa-41 Enriched in several structures, including AVK; GLR; MSpppaaa; coelomocyte; and head mesodermal cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; clk-1; and isp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00018686 F52D2.3 No description available WB:WBGene00018687 F52D2.5 Predicted to be located in membrane. WB:WBGene00018688 F52D2.6 Enriched in B cell; DVA; and body wall muscle cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray and RNA-seq studies. Is affected by four chemicals including cholesterol; Doxycycline; and Chlorpyrifos based on RNA-seq and microarray studies. WB:WBGene00018689 F52D2.7 Expressed in Z1 and Z4. WB:WBGene00018690 fbxa-46 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; anterior hypodermis; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Zidovudine; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018691 fbxa-17 Is affected by spn-4 based on RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00018692 F52E1.2 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Expressed in amphid sheath cell and phasmid sheath cell. Human ortholog(s) of this gene implicated in several diseases, including acquired immunodeficiency syndrome; bronchopulmonary dysplasia; and tuberculosis (multiple). Is an ortholog of several human genes including ASGR1 (asialoglycoprotein receptor 1); CD209 (CD209 molecule); and FCER2 (Fc epsilon receptor II). WB:WBGene00018693 F52E1.3 Enriched in amphid sheath cell and neurons based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and csr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including cadmium; Chlorpyrifos; and Diazinon based on microarray studies. WB:WBGene00018694 F52E1.5 Involved in innate immune response. Expressed in XXXL and XXXR. WB:WBGene00018696 pho-6 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J and prostate cancer. Is an ortholog of human ACP2 (acid phosphatase 2, lysosomal); ACP3 (acid phosphatase 3); and ACP4 (acid phosphatase 4). WB:WBGene00018697 F52E1.9 Predicted to enable phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be located in bounding membrane of organelle and plasma membrane. WB:WBGene00018698 vha-18 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Is an ortholog of human ATP6V1H (ATPase H+ transporting V1 subunit H). WB:WBGene00018699 F52E1.12 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; let-60; and daf-12 based on RNA-seq and microarray studies. Is affected by four chemicals including aldicarb; Sodium Chloride; and resveratrol based on microarray and RNA-seq studies. WB:WBGene00018700 lmd-3 Involved in determination of adult lifespan; response to heat; and response to oxidative stress. Predicted to be located in nucleus. Expressed in head. Human ortholog(s) of this gene implicated in cerebellar hyplasia/atrophy, epilepsy, and global developmental delay. Is an ortholog of human OXR1 (oxidation resistance 1). WB:WBGene00018701 pccb-1 Predicted to enable propionyl-CoA carboxylase activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in propionic acidemia. Is an ortholog of human PCCB (propionyl-CoA carboxylase subunit beta). WB:WBGene00018702 F52E4.5 Enriched in several structures, including arcade cell; head mesodermal cell; pharyngeal cell; rectal gland cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by twelve chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Galactose oxidase/kelch, beta-propeller. WB:WBGene00018703 sec-3 Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to be located in plasma membrane. Predicted to be part of exocyst. Is an ortholog of human EXOC1 (exocyst complex component 1). WB:WBGene00018704 ztf-13 Enriched in several structures, including ABplaapaap; ABplpaaaap; ABplpappaa; ABpraapaap; and pharyngeal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and elt-2 based on RNA-seq; tiling array; and microarray studies. Is affected by nine chemicals including 1-methylnicotinamide; Cry5B; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00018706 F52F10.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00018707 oac-31 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00018708 oac-32 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00018709 srsx-8 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00018710 F52G3.1 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; sek-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including 1-methylnicotinamide; rotenone; and nicotine based on RNA-seq; proteomic; and microarray studies. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Human PRRC2A enables RNA binding activity. Is predicted to encode a protein with the following domains: BAT2 N-terminus; Protein PRRC2; BAT2, N-terminal; and Phosphorylation site. Is an ortholog of human PRRC2A (proline rich coiled-coil 2A); PRRC2B (proline rich coiled-coil 2B); and PRRC2C (proline rich coiled-coil 2C). WB:WBGene00018711 F52G3.3 Enriched in AVK and sensory neurons based on RNA-seq studies. Is affected by several genes including sek-1; pgl-1; and mex-3 based on microarray and RNA-seq studies. Is affected by Doxycycline; Chlorpyrifos; and adsorbable organic bromine compound based on RNA-seq and microarray studies. WB:WBGene00018712 F52G3.4 Enriched in AVK; RID; and seam cell based on RNA-seq studies. Is affected by several genes including rrf-3; sek-1; and tph-1 based on tiling array and RNA-seq studies. Is affected by cholesterol and allantoin based on RNA-seq and microarray studies. WB:WBGene00018713 F52G3.5 Enriched in arcade cell; mechanosensory neurons; and pharyngeal cell based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including multi-walled carbon nanotube; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain; Cysteine-rich repeat; and ShK domain-like. WB:WBGene00018714 F52H2.1 Enriched in coelomocyte and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including pgl-1; aak-2; and atfs-1 based on microarray and RNA-seq studies. Is affected by six chemicals including stavudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018715 F52H2.3 Enriched in GABAergic neurons; PLM; intestine; sensory neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; Zidovudine; and paraquat based on RNA-seq and microarray studies. WB:WBGene00018716 smvt-1 Predicted to enable symporter activity. Predicted to be involved in sodium ion transport. Predicted to be located in membrane. WB:WBGene00018717 F52H2.5 Enriched in several structures, including germ line; germline precursor cell; intestine; mechanosensory neurons; and rectal epithelium based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018718 dhcr-24 Predicted to enable delta24(24-1) sterol reductase activity. Predicted to be involved in steroid metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in lipid metabolism disorder. Is an ortholog of human DHCR24 (24-dehydrocholesterol reductase). WB:WBGene00018719 ccd-5 Predicted to enable calcium ion binding activity and calcium-dependent phospholipid binding activity. Predicted to be involved in positive regulation of transport and protein localization. Predicted to be located in plasma membrane. Is an ortholog of human C2CD5 (C2 calcium dependent domain containing 5). WB:WBGene00018720 F53A3.1 Predicted to be located in membrane. WB:WBGene00018721 polh-1 Predicted to enable DNA-directed DNA polymerase activity. Involved in several processes, including embryo development; error-prone translesion synthesis; and negative regulation of mitotic DNA damage checkpoint. Located in nucleus. Human ortholog(s) of this gene implicated in female breast cancer and xeroderma pigmentosum variant type. Is an ortholog of human POLH (DNA polymerase eta). WB:WBGene00018723 F53A3.7 Predicted to enable protein-folding chaperone binding activity. Predicted to be involved in protein folding; protein import into mitochondrial matrix; and protein stabilization. Predicted to be located in mitochondrion. Is an ortholog of human DNLZ (DNL-type zinc finger). WB:WBGene00018724 F53A9.1 Predicted to be involved in stress response to metal ion. WB:WBGene00018725 kreg-1 Involved in stress response to copper ion. WB:WBGene00018726 F53A9.3 Enriched in GABAergic neurons; XXXL; XXXR; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Tunicamycin; and stavudine based on microarray and RNA-seq studies. WB:WBGene00018727 jbts-14 Involved in non-motile cilium assembly. Located in ciliary basal body and ciliary transition zone. Expressed in ciliated neurons. Used to study Joubert syndrome. Human ortholog(s) of this gene implicated in Joubert syndrome 14. Is an ortholog of human TMEM237 (transmembrane protein 237). WB:WBGene00018728 frpr-8 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00018729 F53A9.6 Involved in innate immune response. WB:WBGene00018730 F53A9.7 Predicted to be involved in stress response to metal ion. WB:WBGene00018731 F53A9.8 Involved in defense response to Gram-positive bacterium. WB:WBGene00018732 F53A9.9 Enriched in GABAergic neurons; pm1; pm2; and rectal gland cell based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Mercuric Chloride; rotenone; and bisphenol S based on microarray and RNA-seq studies. WB:WBGene00018734 F53A10.2 Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in cytoplasm. Expressed in intestine; neurons; and seam cell. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; endocrine gland cancer (multiple); and myelodysplastic syndrome. Is an ortholog of human RAP1GAP (RAP1 GTPase activating protein) and RAP1GAP2 (RAP1 GTPase activating protein 2). WB:WBGene00018735 F53B1.2 Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Is an ortholog of human SAMD8 (sterile alpha motif domain containing 8). WB:WBGene00018736 F53B1.3 Predicted to be located in membrane. WB:WBGene00018738 swip-10 Enriched in several structures, including anterior hypodermis; arc ant V; mechanosensory neurons; tail hypodermis; and ventral cord blast cell based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and pmk-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including methylmercury hydroxide; manganese chloride; and D-glucose based on RNA-seq and microarray studies. Human MBLAC1 enables RNA endonuclease activity and metal ion binding activity. Is predicted to encode a protein with the following domains: Metallo-beta-lactamase; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; Metallo-beta-lactamase domain-containing protein 1; and Metallo-beta-lactamase superfamily. Is an ortholog of human MBLAC1 (metallo-beta-lactamase domain containing 1). WB:WBGene00018739 F53B1.8 Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Is an ortholog of human SLCO4C1 (solute carrier organic anion transporter family member 4C1). WB:WBGene00018740 tra-4 Enables histone deacetylase binding activity. Involved in hermaphrodite somatic sex determination; negative regulation of vulval development; and regulation of gene expression. Located in nucleus. Expressed in several structures, including excretory cell and ventral nerve cord. WB:WBGene00018741 comt-1 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00018742 F53B3.3 Enriched in several structures, including ABaraappaa; MSaaaaapa; MSaapaapa; neuronal sheath cell; and pharyngeal cell based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Armadillo-type fold; Armadillo-like helical; and Phosphorylation site. WB:WBGene00018743 F53B3.5 Predicted to be located in membrane. WB:WBGene00018744 F53B3.6 Enriched in germline precursor cell; hypodermis; rectal epithelial cell; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; nicotinic acid; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018745 F53C3.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00018746 fbxb-103 Expressed in embryonic cell. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00018747 F53C3.3 Predicted to be located in membrane. WB:WBGene00018748 F53C3.4 Predicted to be located in membrane. WB:WBGene00018749 F53C3.5 Enriched in neurons and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; levamisole; and Cadmium Chloride based on RNA-seq and microarray studies. WB:WBGene00018750 F53C3.6 Predicted to be located in membrane. WB:WBGene00018751 F53C3.7 Enriched in several structures, including AVK; MSpppaaa; head mesodermal cell; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and elt-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018752 F53C3.8 Enriched in several structures, including MSpppaaa; Z1.p; head mesodermal cell; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; metformin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018753 F53C3.9 No description available WB:WBGene00018754 F53C3.11 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. WB:WBGene00018755 bcmo-2 Predicted to enable beta-carotene 15,15'-dioxygenase activity and carotenoid dioxygenase activity. Predicted to be involved in carotene catabolic process and retinal metabolic process. Human ortholog(s) of this gene implicated in carcinoma (multiple) and retinal disease (multiple). Is an ortholog of human BCO1 (beta-carotene oxygenase 1); BCO2 (beta-carotene oxygenase 2); and RPE65 (retinoid isomerohydrolase RPE65). WB:WBGene00018756 plpp-1.1 Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. Is an ortholog of human PLPP1 (phospholipid phosphatase 1) and PLPP2 (phospholipid phosphatase 2). WB:WBGene00018757 gid-8 Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in nucleus. Is an ortholog of human GID8 (GID complex subunit 8 homolog). WB:WBGene00018758 F53E10.1 Predicted to enable catalytic activity; molybdenum ion binding activity; and pyridoxal phosphate binding activity. Expressed in head. Is an ortholog of human MTARC1 (mitochondrial amidoxime reducing component 1) and MTARC2 (mitochondrial amidoxime reducing component 2). WB:WBGene00018759 F53E10.3 No description available WB:WBGene00018760 irg-3 Involved in innate immune response. WB:WBGene00018761 F53E10.5 Enriched in several structures, including NSM; Z1.p; germ line; male distal tip cell; and sensory neurons based on RNA-seq and tiling array studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018762 F53E10.6 Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be part of preribosome, large subunit precursor. Expressed in several structures, including body wall musculature and gonad. Is an ortholog of human RRP15 (ribosomal RNA processing 15 homolog). WB:WBGene00018763 F53F10.1 Located in mitochondrion. Is an ortholog of human CCDC102B (coiled-coil domain containing 102B). WB:WBGene00018764 F53F10.2 Predicted to enable catalytic activity. Predicted to be involved in polyamine biosynthetic process. Predicted to be located in cytoplasm. WB:WBGene00018765 mpc-2 Predicted to enable pyruvate transmembrane transporter activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human MPC2 (mitochondrial pyruvate carrier 2). WB:WBGene00018766 F53G2.1 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00018767 F53G2.2 Enriched in ABalapppaa; Y cell; germ line; and pharynx based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and mex-3 based on microarray and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; multi-walled carbon nanotube; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00018768 F53G2.3 Is affected by several genes including eat-2; hpl-2; and hda-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00018769 mnat-1 Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity; kinase activity; and metal ion binding activity. Predicted to be involved in DNA repair and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIH holo complex. Is an ortholog of human MNAT1 (MNAT1 component of CDK activating kinase). WB:WBGene00018771 duox-2 Predicted to enable superoxide-generating NAD(P)H oxidase activity. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and post-embryonic body morphogenesis. Predicted to be located in plasma membrane. Predicted to be part of NADPH oxidase complex. Human ortholog(s) of this gene implicated in cholera; inflammatory bowel disease (multiple); and thyroid dyshormonogenesis 6. Is an ortholog of human DUOX2 (dual oxidase 2). WB:WBGene00018772 F53G12.4 Enriched in several structures, including ABalapapapa; ABalapppapa; ABplaapappp; ciliated neurons; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00018773 F53G12.8 Predicted to be located in membrane. Expressed in sperm. WB:WBGene00018774 F53G12.9 Predicted to be located in cytoplasm. WB:WBGene00018776 ddx-46 Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Is an ortholog of human DDX46 (DEAD-box helicase 46). WB:WBGene00018777 F53H1.3 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in recycling endosome. Is an ortholog of human DENND6A (DENN domain containing 6A) and DENND6B (DENN domain containing 6B). WB:WBGene00018778 F53H1.4 Predicted to enable metal ion binding activity. Predicted to be involved in snRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of integrator complex. Expressed in gonad. WB:WBGene00018779 F53H8.3 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. Expressed in several structures, including Ealaa; Ealp; Earaa; Earp; and intestinal cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Hirschsprung's disease; artery disease (multiple); and brain disease (multiple). Is an ortholog of human SLC2A1 (solute carrier family 2 member 1); SLC2A2 (solute carrier family 2 member 2); and SLC2A4 (solute carrier family 2 member 4). WB:WBGene00018781 F54A3.2 Predicted to enable microtubule binding activity and microtubule plus end polymerase. Predicted to be involved in microtubule cytoskeleton organization. Predicted to be located in kinetochore and microtubule cytoskeleton. Is an ortholog of human CKAP5 (cytoskeleton associated protein 5). WB:WBGene00018782 cct-3 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm and microtubule. Predicted to be part of chaperonin-containing T-complex. Is an ortholog of human CCT3 (chaperonin containing TCP1 subunit 3). WB:WBGene00018783 cbs-2 Predicted to enable cystathionine beta-synthase activity. Predicted to be involved in cysteine biosynthetic process from serine. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including homocystinuria; hyperhomocysteinemia; and neural tube defect. Is an ortholog of human CBS (cystathionine beta-synthase). WB:WBGene00018784 F54A3.5 Predicted to be located in mitochondrion. Predicted to be part of MICOS complex. Is an ortholog of human MICOS10 (mitochondrial contact site and cristae organizing system subunit 10). WB:WBGene00018785 F54A3.6 Enriched in M4 neuron and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018786 hmbx-1 Predicted to enable double-stranded telomeric DNA binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Located in nucleus. Expressed in body wall musculature; enteric muscle; mechanosensory neurons; somatic nervous system; and vulval muscle. Is an ortholog of human HMBOX1 (homeobox containing 1). WB:WBGene00018787 cutl-20 Enriched in several structures, including ABalaaaala; XXX cell; accessory cell; ciliated neurons; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018788 shc-1 Enables insulin-like growth factor receptor binding activity; mitogen-activated protein kinase kinase binding activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in positive regulation of axon regeneration; response to endoplasmic reticulum stress; and response to metal ion. Located in cytoplasm and nucleus. Expressed in gonad; head; neurons; and tail. Human ortholog(s) of this gene implicated in fatty liver disease. Is an ortholog of human SHC4 (SHC adaptor protein 4). WB:WBGene00018789 F54C1.1 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT2B4 (UDP glucuronosyltransferase family 2 member B4). WB:WBGene00018791 F54C1.6 Enriched in head mesodermal cell and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Nucleoside diphosphate kinase-like domain superfamily. WB:WBGene00018792 F54C1.8 Predicted to be located in membrane. WB:WBGene00018793 mrpl-40 Predicted to be located in mitochondrial ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Expressed widely. Used to study chromosome 22q11.2 deletion syndrome, distal. Is an ortholog of human MRPL40 (mitochondrial ribosomal protein L40). WB:WBGene00018794 attf-3 Enriched in ABplapaaap; ABprapaaap; germ line; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; hsf-1; and eat-2 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by six chemicals including rotenone; Zidovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00018795 F54C4.4 Enriched in germ line; neurons; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including skn-1; age-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00018796 F54D7.1 No description available WB:WBGene00018797 ept-1 Predicted to enable ethanolaminephosphotransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be located in Golgi apparatus and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 81. Is an ortholog of human SELENOI (selenoprotein I). WB:WBGene00018798 gnrr-1 Predicted to enable peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cellular response to hormone stimulus. Predicted to be located in plasma membrane. Expressed in intestine; neurons; oocyte; pharynx; and sperm. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 7 with or without anosmia and primary sclerosing cholangitis. Is an ortholog of human GNRHR (gonadotropin releasing hormone receptor). WB:WBGene00018801 F54D8.5 No description available WB:WBGene00018802 F54D8.6 Expressed in head. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018803 fbxa-24 Enriched in several structures, including XXX cell; intestine; neurons; somatic gonad precursor; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including nicotinic acid; Mercuric Chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00018804 lido-15 Predicted to be located in nucleus. WB:WBGene00018805 F54D10.4 Enriched in AFD and germ line based on RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and dcr-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00018806 F54D10.5 Enriched in several structures, including Z1.p; germ line; germline precursor cell; intestine; and male distal tip cell based on RNA-seq studies. Is affected by several genes including glp-1; dpy-10; and hsf-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by ten chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018807 fbxa-146 Enriched in OLL; PVD; XXXL; and XXXR based on microarray and single-cell RNA-seq studies. Is affected by several genes including pgl-1; lin-35; and unc-30 based on microarray and RNA-seq studies. Is affected by nine chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018808 F54D10.7 Enables identical protein binding activity. WB:WBGene00018809 F54D10.8 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00018810 F54D10.9 Enriched in RIH based on single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and nhr-49 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Atrazine; cadmium; and adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00018811 pmt-2 Enables phosphatidyl-N-dimethylethanolamine N-methyltransferase activity and phosphatidyl-N-methylethanolamine N-methyltransferase activity. Involved in phosphatidylcholine biosynthetic process. Is an ortholog of human TMT1A (thiol methyltransferase 1A) and TMT1B (thiol methyltransferase 1B). WB:WBGene00018812 sumv-2 Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of NSL complex. Is an ortholog of human KANSL3 (KAT8 regulatory NSL complex subunit 3). WB:WBGene00018813 F54D11.3 Enriched in ABarppaapp; ABarpppapp; body wall muscle cell from MS lineage; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and rrf-3 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including hydrogen sulfide; methylmercuric chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00018814 F54D11.4 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including skn-1; pgl-1; and lin-39 based on RNA-seq; microarray; and proteomic studies. Is affected by four chemicals including Zidovudine; paraquat; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00018815 F54D12.1 Enriched in ADEshL; ADEshR; pm1; and pm2 based on single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and glh-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Acrylamide based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00018816 F54D12.2 Enriched in ADE sheath cell and anterior ganglion based on single-cell RNA-seq studies. Is affected by drh-3; eat-2; and mex-1 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00018819 rog-1 Predicted to enable fibroblast growth factor receptor binding activity and transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in fibroblast growth factor receptor signaling pathway. Predicted to be located in cytoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in renal cell carcinoma. Is an ortholog of human FRS3 (fibroblast growth factor receptor substrate 3). WB:WBGene00018820 F54D12.7 Is affected by cyc-1; rsr-2; and prg-1 based on microarray and tiling array studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00018821 F54D12.8 Enriched in ADEshL and ADEshR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00018822 F54D12.9 Enriched in excretory cell; interfacial epithelial cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00018823 F54E2.1 Located in membrane raft. WB:WBGene00018824 F54E2.2 Predicted to enable peptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00018825 F54E2.5 Predicted to be located in membrane. WB:WBGene00018826 srt-34 Predicted to be located in membrane. WB:WBGene00018827 pst-2 Enables 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity. Involved in 3'-phosphoadenosine 5'-phosphosulfate transport. Located in Golgi cis cisterna membrane and Golgi medial cisterna membrane. Expressed in hypodermis; intestine; pharyngeal gland cell; and vulva. Is an ortholog of human SLC35B3 (solute carrier family 35 member B3). WB:WBGene00018828 sdz-21 Predicted to be located in membrane. WB:WBGene00018829 F54E7.6 Enriched in several structures, including ABplpaapap; ABprpaapap; Caapa; hyp3; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018830 ska-3 Enriched in several structures, including ABalppppppp; ABplpaappa; ciliated neurons; germ line; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-10; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; manganese chloride; and allantoin based on RNA-seq and microarray studies. WB:WBGene00018831 F54E7.9 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be involved in mitotic sister chromatid cohesion. Predicted to be part of NatA complex. WB:WBGene00018833 ztf-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine and pharyngeal neurons. WB:WBGene00018834 F54F2.6 Is affected by several genes including daf-12; eat-2; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by resveratrol and adsorbable organic bromine compound based on microarray studies. WB:WBGene00018835 F54F2.7 Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in dendrite morphogenesis; regulation of actin filament polymerization; and regulation of filopodium assembly. Predicted to be located in nucleus and plasma membrane bounded cell projection. Is an ortholog of human ABITRAM (actin binding transcription modulator). WB:WBGene00018836 F54F2.9 Predicted to enable DNA binding activity. Predicted to be located in endomembrane system. Expressed in coelomocyte; head neurons; and intestine. Is an ortholog of human DNAJC1 (DnaJ heat shock protein family (Hsp40) member C1). WB:WBGene00018837 F54G2.1 Predicted to be located in secretory vesicle. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 3. Is an ortholog of human BAIAP3 (BAI1 associated protein 3) and UNC13D (unc-13 homolog D). WB:WBGene00018838 F54G2.2 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Sirolimus and bortezomib based on RNA-seq studies. WB:WBGene00018839 F54H5.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00018840 F54H5.3 Predicted to enable FFAT motif binding activity. Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum-plasma membrane tethering. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. WB:WBGene00018841 F54H5.5 Enriched in OLL; PVD; amphid sheath cell; and in male based on microarray and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; Zidovudine; and allantoin based on RNA-seq studies. WB:WBGene00018842 F54H12.2 Predicted to enable ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to be located in cytosol. WB:WBGene00018843 F54H12.3 No description available WB:WBGene00018844 F54H12.4 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and sek-1 based on RNA-seq and microarray studies. Is affected by Rifampin and resveratrol based on RNA-seq and microarray studies. WB:WBGene00018845 F54H12.5 Enriched in several structures, including ABalaaaarl; ABalaaaarr; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00018846 eef-1B.1 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in translational elongation. Predicted to be located in cytosol. Is an ortholog of human EEF1B2 (eukaryotic translation elongation factor 1 beta 2). WB:WBGene00018847 marc-6 Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent ERAD pathway. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 3. Is an ortholog of human MARCHF6 (membrane associated ring-CH-type finger 6). WB:WBGene00018848 F55A3.2 Enriched in NSM; germ line; and intestine based on RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including D-glucose; stavudine; and antimycin based on RNA-seq and microarray studies. WB:WBGene00018849 spt-16 Predicted to enable nucleosome binding activity. Involved in pharynx development; positive regulation of chromosome segregation; and regulation of embryonic development. Located in nucleus. Expressed in several structures, including intestine. Is an ortholog of human SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit). WB:WBGene00018850 gpx-8 Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification. WB:WBGene00018851 F55A3.6 Enriched in coelomocyte; germ line; head mesodermal cell; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including glp-1; let-60; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by Alovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018852 F55A3.7 Enriched in germ line and head mesodermal cell based on proteomic and RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and let-7 based on microarray; proteomic; and RNA-seq studies. Is affected by eight chemicals including stavudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00018853 sec-22 Predicted to enable SNAP receptor activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment and organelle membrane. Predicted to be part of SNARE complex. Expressed in somatic cell and tail. Used to study Parkinson's disease. Is an ortholog of human SEC22B (SEC22 homolog B, vesicle trafficking protein). WB:WBGene00018854 nlf-1 Expressed in nervous system. WB:WBGene00018855 F55A4.3 Predicted to be located in membrane. Expressed in amphid neurons and phasmid neurons. WB:WBGene00018856 F55A4.4 Enriched in AVK; OLL; PVD; body wall musculature; and head mesodermal cell based on microarray and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00018857 stau-1 Enables double-stranded RNA binding activity. Involved in germ cell development and negative regulation of post-transcriptional gene silencing by regulatory ncRNA. Predicted to be located in several cellular components, including cytoplasmic stress granule; neuron projection; and neuronal cell body. Predicted to be part of messenger ribonucleoprotein complex. Human ortholog(s) of this gene implicated in atherosclerosis. Is an ortholog of human STAU1 (staufen double-stranded RNA binding protein 1). WB:WBGene00018858 F55A4.6 No description available WB:WBGene00018859 F55A4.7 Enriched in I5 neuron; MSaapaapa; MSpapaapa; PVP; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and lin-35 based on RNA-seq and microarray studies. Is affected by five chemicals including Tunicamycin; Sodium Chloride; and stearic acid based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Calponin repeat and Calponin family repeat. WB:WBGene00018860 vpat-1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC18B1 (solute carrier family 18 member B1). WB:WBGene00018861 cutl-21 Predicted to be located in membrane. WB:WBGene00018862 wago-2 Enriched in several structures, including AVK; NSM; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and microarray studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including manganese chloride; D-glucose; and bisphenol S based on RNA-seq; proteomic; and microarray studies. WB:WBGene00018863 F55A12.2 Predicted to be located in membrane. WB:WBGene00018864 F55A12.5 Predicted to be located in nucleolus. WB:WBGene00018865 F55A12.6 Is affected by several genes including daf-16; skn-1; and clk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Mercuric Chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00018866 nath-10 Predicted to enable rRNA cytidine N-acetyltransferase activity and tRNA binding activity. Predicted to be involved in rRNA acetylation involved in maturation of SSU-rRNA. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Expressed in head; seam cell; and tail. Is an ortholog of human NAT10 (N-acetyltransferase 10). WB:WBGene00018867 zhp-1 Predicted to enable SUMO transferase activity. Predicted to be involved in homologous chromosome pairing at meiosis and protein sumoylation. Predicted to be located in synaptonemal complex. Human ortholog(s) of this gene implicated in spermatogenic failure 62. Is an ortholog of human RNF212 (ring finger protein 212) and RNF212B (ring finger protein 212B). WB:WBGene00018868 F55C7.2 Expressed in intestinal muscle. WB:WBGene00018869 rfip-1 Predicted to be involved in endocytic recycling and regulation of cytokinesis. Predicted to be located in cleavage furrow; cytoplasmic vesicle; and midbody. Expressed in several structures, including excretory canal; head neurons; intestine; pharynx; and tail neurons. Is an ortholog of human RAB11FIP3 (RAB11 family interacting protein 3) and RAB11FIP4 (RAB11 family interacting protein 4). WB:WBGene00018870 F55C12.2 Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by paraquat; adsorbable organic bromine compound; and Sirolimus based on microarray studies. WB:WBGene00018871 F55C12.4 Predicted to be located in membrane. Expressed in neurons. WB:WBGene00018872 tex-2 Predicted to enable lipid binding activity. Predicted to be involved in lipid transport. Predicted to be located in endoplasmic reticulum. Expressed in AIYL and AIYR. Is an ortholog of human TEX2 (testis expressed 2). WB:WBGene00018873 F55C12.6 Enriched in PLM and germ line based on RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; Domain of unknown function DUF1248; and Protein of unknown function (DUF1248). WB:WBGene00018874 tag-234 Enriched in head mesodermal cell and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and levamisole based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00018875 F55D1.1 Is affected by several genes including eat-2; sir-2.1; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including metformin; Sirolimus; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00018877 aman-1 Predicted to enable alpha-mannosidase activity. Predicted to be involved in mannose metabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in alpha-mannosidosis. Is an ortholog of human MAN2B1 (mannosidase alpha class 2B member 1). WB:WBGene00018878 glit-1 Predicted to enable neurexin family protein binding activity and signaling receptor activity. Involved in cellular response to paraquat and negative regulation of response to oxidative stress. Predicted to be located in cell surface and synapse. Expressed in dopaminergic neurons and head. Used to study Parkinson's disease. WB:WBGene00018879 F55D10.4 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00018880 acc-3 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Predicted to be part of chloride channel complex. WB:WBGene00018881 F55E10.1 Predicted to be located in membrane. WB:WBGene00018882 F55E10.2 Predicted to be located in membrane. WB:WBGene00018883 F55E10.4 Predicted to be located in membrane. WB:WBGene00018884 F55E10.5 Enriched in head neurons based on single-cell RNA-seq studies. Is affected by several genes including eat-2; rrf-1; and csr-1 based on RNA-seq and microarray studies. Is affected by dafa#1 and Sirolimus based on microarray studies. WB:WBGene00018885 drd-5 Predicted to enable oxidoreductase activity. Predicted to be involved in steroid metabolic process. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 13; fundus albipunctatus; and night blindness. Is an ortholog of several human genes including DHRS9 (dehydrogenase/reductase 9); HSD17B6 (hydroxysteroid 17-beta dehydrogenase 6); and RDH5 (retinol dehydrogenase 5). WB:WBGene00018886 npr-28 Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection. Expressed in head neurons; tail neurons; and in male. WB:WBGene00018888 F55F1.2 Enriched in body wall muscle cell based on tiling array studies. Is affected by mex-1; egl-43; and ain-2 based on RNA-seq and microarray studies. Is affected by Atrazine based on microarray studies. WB:WBGene00018890 F55F8.2 Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be located in nucleolus. Is an ortholog of human DDX24 (DEAD-box helicase 24). WB:WBGene00018891 F55F8.3 Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and ribosomal small subunit assembly. Predicted to be located in nucleolus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Is an ortholog of human PWP2 (PWP2 small subunit processome component). WB:WBGene00018892 cir-1 Enables protein self-association. Involved in oogenesis. Located in nucleus. Is an ortholog of human CIR1 (corepressor interacting with RBPJ, CIR1). WB:WBGene00018893 wdr-12 Predicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of PeBoW complex. Is an ortholog of human WDR12 (WD repeat domain 12). WB:WBGene00018894 mff-2 Predicted to be involved in mitochondrial fission; positive regulation of mitochondrial fission; and positive regulation of protein targeting to membrane. Predicted to be located in mitochondrial outer membrane and peroxisome. Human ortholog(s) of this gene implicated in brain disease. Is an ortholog of human MFF (mitochondrial fission factor). WB:WBGene00018895 F55F8.7 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00018896 F55F8.8 Enriched in AMsoL; AMsoR; excretory duct; and excretory pore based on single-cell RNA-seq studies. Is affected by several genes including pmk-1; clk-1; and dpy-7 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018897 zipt-2.4 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to be located in plasma membrane. WB:WBGene00018898 F55F10.1 Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in ribosomal large subunit assembly and ribosomal large subunit export from nucleus. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human MDN1 (midasin AAA ATPase 1). WB:WBGene00018899 F55G1.1 Predicted to be located in membrane. WB:WBGene00018900 rod-1 Enables protein domain specific binding activity. Involved in several processes, including chromosome organization; positive regulation of kinetochore assembly; and regulation of cell cycle process. Part of RZZ complex. Is an ortholog of human KNTC1 (kinetochore associated 1). WB:WBGene00018901 slc-25A18.2 Predicted to enable L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport; aspartate transmembrane transport; and malate-aspartate shuttle. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 3. Is an ortholog of human SLC25A18 (solute carrier family 25 member 18) and SLC25A22 (solute carrier family 25 member 22). WB:WBGene00018902 F55G1.6 Predicted to be located in membrane. Expressed in virL and virR. WB:WBGene00018903 F55G1.7 Enriched in cephalic sheath cell; germ line; intestine; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and pmk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Zidovudine; tert-Butylhydroperoxide; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00018904 pycr-4 Predicted to enable pyrroline-5-carboxylate reductase activity. Predicted to be involved in L-proline biosynthetic process. Expressed in hypodermis and intestinal cell. WB:WBGene00018906 egas-4 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00018907 F55G1.15 Predicted to be located in membrane. WB:WBGene00018908 fncm-1 Enriched in Z1.p; Z4.a; germ line; germline precursor cell; and male distal tip cell based on RNA-seq studies. Is affected by several genes including skn-1; dpy-10; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018909 slx-1 Enables enzyme binding activity. Contributes to 3'-flap endonuclease activity; 5'-flap endonuclease activity; and crossover junction DNA endonuclease activity. Involved in several processes, including DNA metabolic process; meiotic chromosome separation; and regulation of multicellular organismal development. Part of Slx1-Slx4 complex. Is an ortholog of human SLX1A (SLX1 homolog A, structure-specific endonuclease subunit) and SLX1B (SLX1 homolog B, structure-specific endonuclease subunit). WB:WBGene00018910 F56A4.2 Enriched in intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Mercuric Chloride; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00018911 F56A4.3 Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); hematologic cancer (multiple); and lung disease (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). WB:WBGene00018912 F56A4.4 Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); hematologic cancer (multiple); and lung disease (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). WB:WBGene00018913 F56A4.5 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00018914 F56A4.6 Is affected by several genes including pgl-1; bar-1; and glh-1 based on tiling array; microarray; and RNA-seq studies. Is affected by cadmium based on microarray studies. WB:WBGene00018915 str-267 Enriched in AVK based on RNA-seq and microarray studies. Is affected by several genes including eat-2; pgl-1; and lin-35 based on microarray and RNA-seq studies. Is affected by nine chemicals including mianserin; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class r (Str) and Serpentine type 7TM GPCR chemoreceptor Str. WB:WBGene00018916 F56A4.8 No description available WB:WBGene00018917 irld-35 Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; quantitative PCR; and RNA-seq studies. Is affected by R24 and fluvastatin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00018918 F56A4.10 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00018919 F56A4.11 Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Lithium Chloride based on microarray studies. WB:WBGene00018920 F56A4.12 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00018921 sago-2 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. WB:WBGene00018922 F56A6.3 No description available WB:WBGene00018923 eme-1 Enables enzyme binding activity. Predicted to be involved in double-strand break repair via break-induced replication; mitotic intra-S DNA damage checkpoint signaling; and resolution of meiotic recombination intermediates. Predicted to be located in nucleus. Predicted to be part of Holliday junction resolvase complex. WB:WBGene00018924 F56A11.4 Predicted to be located in membrane. WB:WBGene00018925 F56A11.5 Predicted to enable catalytic activity; molybdenum ion binding activity; and pyridoxal phosphate binding activity. Predicted to be located in membrane. Is an ortholog of human MTARC1 (mitochondrial amidoxime reducing component 1) and MTARC2 (mitochondrial amidoxime reducing component 2). WB:WBGene00018926 F56A11.6 Predicted to be located in membrane. WB:WBGene00018928 F56B3.2 Enriched in several structures, including NSM; anterior hypodermis; germ line; interfacial epithelial cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including mianserin; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: EB domain and EB module. WB:WBGene00018929 F56B3.3 Is affected by several genes including sir-2.1; hrde-1; and mut-16 based on RNA-seq and microarray studies. Is affected by cholesterol and Atrazine based on RNA-seq and microarray studies. WB:WBGene00018930 F56B3.6 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 77. Is an ortholog of human REEP5 (receptor accessory protein 5) and REEP6 (receptor accessory protein 6). WB:WBGene00018931 ugt-52 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT8 (UDP glycosyltransferase 8). WB:WBGene00018932 mrpl-2 Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL2 (mitochondrial ribosomal protein L2). WB:WBGene00018933 F56B3.9 Enriched in NSM based on tiling array studies. Is affected by several genes including eat-2; sir-2.1; and mex-3 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00018934 F56B3.11 Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is an ortholog of human TIMM21 (translocase of inner mitochondrial membrane 21). WB:WBGene00018935 skr-18 Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). WB:WBGene00018937 F56B6.6 Expressed in pharyngeal gland cell and tail neurons. Is predicted to encode a protein with the following domain: Cysteine-rich repeat. WB:WBGene00018938 F56C3.1 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including cadmium; Diazinon; and dibromoacetic acid based on RNA-seq and microarray studies. WB:WBGene00018939 fbxa-190 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00018940 F56C3.3 Predicted to be located in membrane. WB:WBGene00018941 F56C3.4 Predicted to be located in membrane. WB:WBGene00018942 F56C3.5 Is affected by clk-1 and eat-2 based on microarray studies. Is affected by Atrazine and allantoin based on microarray studies. WB:WBGene00018943 dgn-2 Predicted to enable laminin binding activity. Predicted to be involved in axon guidance; morphogenesis of an epithelium; and nerve development. Predicted to be located in sarcolemma. Predicted to be part of dystroglycan complex. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; Fukuyama congenital muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2D; autosomal recessive limb-girdle muscular dystrophy type 2P; bronchopulmonary dysplasia; congenital muscular dystrophy-dystroglycanopathy type A9; and inclusion body myositis. Is an ortholog of human DAG1 (dystroglycan 1). WB:WBGene00018944 F56C3.7 Predicted to be located in membrane. WB:WBGene00018945 F56C3.8 Enriched in g2; rectal gland cell; tail hypodermis; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; sir-2.1; and tph-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including multi-walled carbon nanotube; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00018946 F56C3.9 Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-two chemicals including hydrogen sulfide; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00018947 F56C9.2 No description available WB:WBGene00018948 F56C9.3 Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in membrane. WB:WBGene00018949 acbp-4 Predicted to enable fatty-acyl-CoA binding activity. Predicted to be involved in fatty acid metabolic process. Predicted to be located in cytoplasm. Expressed in intestine. WB:WBGene00018950 F56C9.6 Enriched in M cell; germ line; germline precursor cell; head mesodermal cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eleven chemicals including rotenone; bisphenol S; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018951 nspg-6 Involved in regulation of lipid storage and regulation of peptide transport. WB:WBGene00018952 F56C9.8 Predicted to be located in membrane. WB:WBGene00018953 F56C9.10 Predicted to be involved in response to starvation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Hengel-Maroofian-Schols syndrome and breast cancer. Is an ortholog of human BCAS3 (BCAS3 microtubule associated cell migration factor). WB:WBGene00018954 lab-2 Enriched in MSpaaaaa; germ line; rectal epithelial cell; rectum; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00018955 F56C11.3 Predicted to enable flavin adenine dinucleotide binding activity and flavin-dependent sulfhydryl oxidase activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in kidney failure and renal fibrosis. Is an ortholog of human GFER (growth factor, augmenter of liver regeneration). WB:WBGene00018957 F56C11.5 Predicted to be located in membrane. WB:WBGene00018958 cest-27 Predicted to enable carboxylic ester hydrolase activity. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). WB:WBGene00018959 F56D1.1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00018960 ilcr-2 Predicted to enable interleukin-17 receptor activity. Involved in positive regulation of locomotion. Located in plasma membrane. Part of receptor complex. Expressed in RMGL; RMGR; body wall musculature; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in immunodeficiency 51. Is an ortholog of human IL17RA (interleukin 17 receptor A). WB:WBGene00018961 mrps-16 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 2. Is an ortholog of human MRPS16 (mitochondrial ribosomal protein S16). WB:WBGene00018963 ucr-1 Predicted to enable metal ion binding activity. Located in mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human UQCRC1 (ubiquinol-cytochrome c reductase core protein 1). WB:WBGene00018964 F56D2.2 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human RNF14 (ring finger protein 14). WB:WBGene00018965 F56D2.3 Enriched in several structures, including MSaaaaapa; MSaapaapa; arcade cell; mechanosensory neurons; and pharynx based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including 1-methylnicotinamide; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00018966 F56D2.5 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Involved in innate immune response. Predicted to be located in cytoplasm. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human RNF14 (ring finger protein 14). WB:WBGene00018967 ddx-15 Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human DHX15 (DEAH-box helicase 15). WB:WBGene00018968 F56D2.8 Enriched in hypodermis; neurons; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: NTF2-like domain superfamily. WB:WBGene00018969 F56D3.1 Enriched in germ line; germline precursor cell; hypodermis; mechanosensory neurons; and rectal epithelial cell based on proteomic; microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-eight chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00018970 clec-68 Involved in innate immune response. WB:WBGene00018971 clec-67 Involved in PERK-mediated unfolded protein response. Expressed in intestine. WB:WBGene00018972 srz-19 Predicted to be located in membrane. WB:WBGene00018973 srz-20 Predicted to be located in membrane. WB:WBGene00018974 fcho-1 Involved in clathrin-dependent endocytosis. Located in plasma membrane. Expressed in amphid neurons; hypodermis; intestine; pharyngeal cell; and rectal gland cell. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human FCHO2 (FCH and mu domain containing endocytic adaptor 2). WB:WBGene00018975 picd-1 Predicted to contribute to nucleosome binding activity. Predicted to be involved in chromatin organization. Predicted to be located in nucleus. Expressed in several structures, including body wall musculature; head neurons; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in ovarian carcinoma. Is an ortholog of human CABIN1 (calcineurin binding protein 1). WB:WBGene00018976 daam-1 Predicted to enable actin binding activity and small GTPase binding activity. Predicted to be involved in positive regulation of actin filament polymerization. Human ortholog(s) of this gene implicated in familial nephrotic syndrome. Is an ortholog of human DAAM2 (dishevelled associated activator of morphogenesis 2). WB:WBGene00018978 ttr-58 Predicted to be located in cell surface and extracellular region. WB:WBGene00018979 ttr-55 Predicted to be located in cell surface and extracellular region. WB:WBGene00018980 F56F4.3 Predicted to be located in membrane. WB:WBGene00018981 F56F4.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including Doxycycline; paraquat; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00018982 abt-6 Is affected by several genes including sir-2.1; drh-3; and smg-2 based on microarray and RNA-seq studies. Is affected by four chemicals including Tunicamycin; Lithium Chloride; and lithium carbonate based on microarray studies. WB:WBGene00018983 F56F4.7 No description available WB:WBGene00018984 F56F10.1 Predicted to enable dipeptidyl-peptidase activity. Involved in innate immune response. Located in membrane raft. Is an ortholog of human PRSS16 (serine protease 16). WB:WBGene00018985 F56F10.2 Enriched in several structures, including body muscle cell; coelomocyte; head mesodermal cell; neurons; and ventral nerve cord based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily and F-box domain. WB:WBGene00018986 cdo-1 Predicted to enable cysteine dioxygenase activity and ferrous iron binding activity. Predicted to be involved in L-cysteine catabolic process. Expressed in tail. Is an ortholog of human CDO1 (cysteine dioxygenase type 1). WB:WBGene00018987 lgl-1 Predicted to enable GTPase activator activity; myosin II binding activity; and syntaxin binding activity. Involved in establishment of spindle orientation and protein localization. Located in basolateral plasma membrane and cell cortex. Expressed in epithelial cell; intestine; spermathecal cell; and vulval cell. Is an ortholog of human LLGL1 (LLGL scribble cell polarity complex component 1) and LLGL2 (LLGL scribble cell polarity complex component 2). WB:WBGene00018988 F56F11.1 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00018989 F56F11.2 Enriched in AFD; GABAergic neurons; head mesodermal cell; muscle cell; and touch receptor neurons based on microarray and RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and hsp-6 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00018990 klf-1 Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including apoptotic cell clearance; regulation of transcription by RNA polymerase II; and xenobiotic metabolic process. Acts upstream of or within determination of adult lifespan. Part of chromatin. Expressed in hypodermis; intestine; and neurons. Human ortholog(s) of this gene implicated in prostate cancer and stomach cancer. Is an ortholog of human KLF6 (KLF transcription factor 6). WB:WBGene00018991 F56F11.4 Predicted to enable proteasome-activating activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of proteasome regulatory particle, base subcomplex. Is an ortholog of human PSMC5 (proteasome 26S subunit, ATPase 5). WB:WBGene00018992 trpl-1 Is affected by several genes including skn-1; rrf-3; and sir-2.1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00018993 nhr-266 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by cholesterol; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00018994 F56H1.3 Enriched in ABalpppapa; ABpraaaapa; germ line; mechanosensory neurons; and in male based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq; tiling array; and microarray studies. Is affected by ten chemicals including hydrogen sulfide; methylmercuric chloride; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00018995 ccpp-1 Predicted to enable metallocarboxypeptidase activity and zinc ion binding activity. Involved in egg-laying behavior. Predicted to be located in cilium; dendrite; and perikaryon. Expressed in ciliated neurons and gubernacular muscle. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy. Is an ortholog of human AGBL1 (AGBL carboxypeptidase 1). WB:WBGene00018996 F57B9.1 Predicted to enable pyridoxamine phosphate oxidase activity. Predicted to be involved in pyridoxal phosphate biosynthetic process. Human ortholog(s) of this gene implicated in pyridoxamine 5'-phosphate oxidase deficiency. Is an ortholog of human PNPO (pyridoxamine 5'-phosphate oxidase). WB:WBGene00018997 F57B9.3 Predicted to enable translation initiation factor activity. Involved in translation. Predicted to be located in cytoplasmic stress granule. Is an ortholog of human EIF4A2 (eukaryotic translation initiation factor 4A2). WB:WBGene00018998 flap-1 Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of human LRRFIP2 (LRR binding FLII interacting protein 2). WB:WBGene00018999 F57B9.8 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00019001 ipgm-1 Enables 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity. Involved in carbohydrate metabolic process. Predicted to be located in cytoplasm. Expressed in body wall musculature; intestine; and nerve ring. WB:WBGene00019002 syp-6 Enriched in germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including manganese chloride; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00019003 tmed-3 Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human TMED7 (transmembrane p24 trafficking protein 7) and TMED7-TICAM2 (TMED7-TICAM2 readthrough). WB:WBGene00019004 xpg-1 Predicted to enable 5'-flap endonuclease activity. Predicted to be involved in double-strand break repair via homologous recombination. Human ortholog(s) of this gene implicated in several diseases, including cerebrooculofacioskeletal syndrome 3; respiratory system cancer (multiple); and xeroderma pigmentosum group G. Is an ortholog of human ERCC5 (ERCC excision repair 5, endonuclease). WB:WBGene00019005 F57B10.8 Predicted to enable RNA binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Is an ortholog of human ABT1 (activator of basal transcription 1). WB:WBGene00019006 spg-20 Predicted to be involved in cell division and negative regulation of BMP signaling pathway. Predicted to be located in plasma membrane. Expressed in IL2DL; IL2DR; IL2VL; IL2VR; and body wall musculature. Human ortholog(s) of this gene implicated in Troyer syndrome. Is an ortholog of human SPART (spartin). WB:WBGene00019007 ucr-11 Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. WB:WBGene00019008 pdxk-1 Predicted to enable pyridoxal kinase activity. Predicted to be involved in pyridoxal 5'-phosphate salvage. Predicted to be located in cytosol. Is an ortholog of human PDXK (pyridoxal kinase). WB:WBGene00019009 clec-90 Predicted to be located in membrane. WB:WBGene00019010 glo-2 Enables protein homodimerization activity. Involved in endosomal transport and positive regulation of intracellular protein transport. Located in endosome. Expressed in intestine and seam cell. Used to study Hermansky-Pudlak syndrome. WB:WBGene00019011 F57C9.4 Expressed in gonad; hypodermis; and intestine. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type; Zinc finger, C2H2 type; and Zinc finger C2H2 superfamily. WB:WBGene00019012 F57C9.6 Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to be located in membrane. WB:WBGene00019013 tofu-4 Expressed in germ cell. WB:WBGene00019014 F57C12.2 Predicted to enable metal ion binding activity. WB:WBGene00019015 F57F4.1 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human ACOT9 (acyl-CoA thioesterase 9). WB:WBGene00019016 F57F4.2 Enriched in body wall muscle cell; dopaminergic neurons; intestine; neurons; and pm8 based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019017 bcf-1 Located in membrane raft. WB:WBGene00019018 abts-3 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic ion homeostasis and transmembrane transport. Predicted to be located in basolateral plasma membrane. Expressed in hypodermis and neurons. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy; congenital hereditary endothelial dystrophy of cornea; and corneal dystrophy-perceptive deafness syndrome. Is an ortholog of human SLC4A11 (solute carrier family 4 member 11). WB:WBGene00019019 frpr-10 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00019020 F57H12.5 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00019021 F57H12.6 Enriched in hypodermis; intestine; male-specific anatomical entity; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; microarray; and RNA-seq studies. Is affected by thirty-two chemicals including Nitric Oxide; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq and microarray studies. WB:WBGene00019022 F58A6.1 Predicted to enable delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Is an ortholog of human ECH1 (enoyl-CoA hydratase 1). WB:WBGene00019023 F58A6.2 Predicted to be located in membrane. WB:WBGene00019024 F58A6.5 Predicted to be located in membrane. WB:WBGene00019025 srb-16 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in dendrite; perikaryon; and plasma membrane. Expressed in neurons; pharyngeal muscle cell; tail; and in male. WB:WBGene00019026 F58A6.9 Enriched in amphid sheath cell; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-nine chemicals including aldicarb; Ethanol; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00019027 srb-12 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in dendrite; perikaryon; and plasma membrane. Expressed in head. WB:WBGene00019028 srb-13 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be located in dendrite; perikaryon; and plasma membrane. Expressed in amphid neurons. WB:WBGene00019029 F58B6.1 Predicted to be involved in lipid metabolic process. WB:WBGene00019030 exc-6 Predicted to enable actin binding activity. Involved in epithelium development; regulation of microtubule polymerization; and regulation of tube size. Part of filamentous actin. Is an ortholog of human FHDC1 (FH2 domain containing 1). WB:WBGene00019032 srsx-17 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in nervous system. WB:WBGene00019033 F58E1.1 No description available WB:WBGene00019034 fbxb-25 Enriched in ABalpppappp; ABpraaaappp; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including iron oxide nanoparticle; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019035 fbxb-26 Enriched in several structures, including ABalpppappp; ABalppppaa; ABalpppppa; amphid neurons; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including mianserin; multi-walled carbon nanotube; and bisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019036 irld-36 Predicted to be located in membrane. WB:WBGene00019037 fbxb-17 Enriched in ABaraapapaa; ABaraapppaa; and head ganglion based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; Mercuric Chloride; and bisphenol A based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019038 irld-37 Enriched in ASJL; ASJR; NSM; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019039 fbxb-18 Enriched in several structures, including ABalpppapa; ABalpppappp; ABalppppaa; NSM; and ciliated neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; mianserin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019040 fbxb-19 Enriched in several structures, including ABalpppapa; ABalpppappp; ABalppppaa; ABalpppppa; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; bisphenol S; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00019041 fbxc-22 Enriched in ABalapppaa; ABalppppaa; and ABpraaapaa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including Mercuric Chloride; multi-walled carbon nanotube; and bisphenol A based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019042 fbxc-21 Enriched in ABplpappaa; AIY; dopaminergic neurons; hypodermis; and tail precursor cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including iron oxide nanoparticle; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019043 fbxc-26 Enriched in body wall muscle cell based on single-cell RNA-seq studies. Is affected by several genes including let-60; lin-4; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019044 F58E1.13 Enriched in AFD and NSM based on tiling array and RNA-seq studies. Is affected by several genes including let-60; lin-4; and lin-14 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019045 fbxb-47 Enriched in ADEshL; ADEshR; NSM; and germ line based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and alg-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019046 F58E2.2 Enriched in several structures, including cephalic sheath cell; coelomocyte; dopaminergic neurons; mechanosensory neurons; and ventral nerve cord based on tiling array studies. Is affected by several genes including rrf-3; sir-2.1; and rrf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Rifampin; allantoin; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00019047 F58E2.3 Enriched in body wall muscle cell; coelomocyte; hypodermis; neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00019048 F58E2.4 Enriched in several structures, including PLM; Y cell; body wall muscle cell; intestine; and male distal tip cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00019049 F58E2.5 Predicted to be located in extracellular space. WB:WBGene00019050 srz-88 Is affected by qui-1 and let-60 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00019051 srz-23 Predicted to be located in membrane. WB:WBGene00019053 F58F6.5 Predicted to be located in membrane. WB:WBGene00019054 F58F6.6 Predicted to be located in membrane. WB:WBGene00019055 F58F9.1 Enriched in several structures, including ABalpppappp; ABalppppppp; ABplaapappp; ABplapaaaap; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00019057 F58F9.3 Predicted to enable endonuclease activity. WB:WBGene00019058 F58F9.4 Enriched in CEM; HOB; IL2 neuron; intestine; and ray neuron type B based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including 4-bromodiphenyl ether; Rifampin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF272) and Protein of unknown function DUF272. WB:WBGene00019059 F58F9.6 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and tph-1 based on microarray and RNA-seq studies. Is affected by Zidovudine and allantoin based on RNA-seq and microarray studies. WB:WBGene00019060 acox-3 Predicted to enable fatty acid binding activity; flavin adenine dinucleotide binding activity; and pristanoyl-CoA oxidase activity. Involved in ascaroside biosynthetic process. Located in peroxisome. Expressed in intestinal cell. Is an ortholog of human ACOX3 (acyl-CoA oxidase 3, pristanoyl). WB:WBGene00019061 F58F12.1 Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Located in mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human ATP5F1D (ATP synthase F1 subunit delta). WB:WBGene00019062 F58F12.2 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; D-glucose; and antimycin based on microarray and RNA-seq studies. WB:WBGene00019063 F58F12.3 Enriched in GLR; germ line; interneuron; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; RNA-seq; and tiling array studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00019064 myo-5 Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in muscle contraction and sarcomere organization. Predicted to be located in cytoplasm and myosin filament. Predicted to be part of myosin II complex. Human ortholog(s) of this gene implicated in several diseases, including congenital heart disease (multiple); distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3). WB:WBGene00019065 srlf-16 Enriched in neurons based on RNA-seq studies. Is affected by rsr-2 based on tiling array studies. Is affected by Atrazine; Chlorpyrifos; and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00019066 sdz-23 Predicted to enable Notch binding activity. Predicted to be located in membrane. Expressed in E; Ea; and Ep. WB:WBGene00019067 F58H7.1 Enriched in neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Tunicamycin; multi-walled carbon nanotube; and Testosterone based on microarray and RNA-seq studies. WB:WBGene00019068 faah-3 Predicted to enable amidase activity and fatty acid amide hydrolase activity. Predicted to be involved in fatty acid catabolic process. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Is an ortholog of human FAAH (fatty acid amide hydrolase). WB:WBGene00019069 lgc-30 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00019070 F58H7.5 Enriched in ABplapaaaa; ABprapaaaa; germ line; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00019071 F58H7.6 No description available WB:WBGene00019072 fbxc-8 Enriched in body wall muscle cell and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019073 fbxc-3 Enriched in intestine and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including D-glucopyranose; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019074 cpd-1 Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in peptide metabolic process and protein processing. Predicted to be located in extracellular space. Is an ortholog of human CPD (carboxypeptidase D). WB:WBGene00019075 F59A3.2 Enriched in germ line; germline precursor cell; intestine; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; glp-1; and let-60 based on microarray and RNA-seq studies. Is affected by nine chemicals including bisphenol S; Alovudine; and Zidovudine based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019076 mrpl-24 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human MRPL24 (mitochondrial ribosomal protein L24). WB:WBGene00019077 zipt-11 Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC39A11 (solute carrier family 39 member 11). WB:WBGene00019079 rpa-4 Predicted to enable single-stranded DNA binding activity and telomeric DNA binding activity. Predicted to be involved in DNA replication; double-strand break repair via homologous recombination; and nucleotide-excision repair. Predicted to be located in chromosome, telomeric region and site of double-strand break. Predicted to be part of DNA replication factor A complex. Is an ortholog of human RPA2 (replication protein A2) and RPA4 (replication protein A4). WB:WBGene00019080 F59A3.7 Predicted to be located in membrane. WB:WBGene00019081 F59A3.8 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00019082 pup-3 Predicted to be involved in mRNA polyadenylation. WB:WBGene00019084 F59A6.2 Predicted to be located in ribosome. WB:WBGene00019085 F59A6.3 Enriched in neurons and in male based on RNA-seq and microarray studies. Is affected by several genes including eat-2; sir-2.1; and eri-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including aldicarb; allantoin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Uncharacterized protein F26C11.3-like. WB:WBGene00019086 F59A6.4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00019087 citk-2 Predicted to be involved in actomyosin structure organization. Predicted to be located in cytoplasm and cytoskeleton. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 17. Is an ortholog of human CIT (citron rho-interacting serine/threonine kinase). WB:WBGene00019089 clec-206 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including Ethanol; tryptophan; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00019090 F59A7.2 Involved in defense response to Gram-negative bacterium. WB:WBGene00019091 srab-13 Predicted to be located in membrane. Expressed in amphid neurons; vulval cell; and in male. WB:WBGene00019092 F59A7.5 Enriched in amphid sheath cell and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019094 F59A7.7 Predicted to enable cysteine synthase activity. Predicted to be involved in cysteine biosynthetic process from serine. Predicted to be located in cytoplasm. WB:WBGene00019095 F59A7.8 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by Alovudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00019096 cysl-4 Predicted to enable cysteine synthase activity. Predicted to be involved in cysteine biosynthetic process from serine. Predicted to be located in cytoplasm. WB:WBGene00019097 F59B1.2 Enriched in germ line; head mesodermal cell; intestine; mechanosensory neurons; and pharyngeal muscle cell based on proteomic; microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and pie-1 based on RNA-seq; microarray; and proteomic studies. Is affected by twenty-two chemicals including mianserin; D-glucose; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00019098 F59B1.4 Predicted to be located in membrane. WB:WBGene00019099 F59B1.6 Predicted to be located in membrane. WB:WBGene00019100 F59B1.8 Predicted to enable kinase activity. Involved in innate immune response. WB:WBGene00019101 F59B1.10 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00019102 F59C12.3 Enriched in several structures, including ABprpapppa; RIH; excretory cell; head mesodermal cell; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and sek-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nine chemicals including 1-methylnicotinamide; D-glucose; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Nucleotidyltransferase superfamily and Phosphorylation site. WB:WBGene00019103 F59D6.1 Enriched in several structures, including AFD; Caaaaa; Caaaap; Caaapa; and Caaapp based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00019104 asp-7 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in Alzheimer's disease and frontotemporal dementia. Is an ortholog of human BACE1 (beta-secretase 1); BACE2 (beta-secretase 2); and PGC (progastricsin). WB:WBGene00019105 asp-8 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Is an ortholog of human PGC (progastricsin). WB:WBGene00019106 irld-38 Enriched in ASJ and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including drh-3; mir-34; and etr-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00019107 irld-10 Is affected by several genes including clk-1; lin-15B; and cyc-1 based on microarray; tiling array; and RNA-seq studies. WB:WBGene00019108 chpf-2 Predicted to enable calcium ion binding activity. Predicted to be located in plasma membrane. Expressed in ray and in male. Human ortholog(s) of this gene implicated in spastic ataxia. Is an ortholog of human CHP1 (calcineurin like EF-hand protein 1). WB:WBGene00019109 F59E11.2 Enriched in XXX cell; amphid sheath cell; arc ant V; and excretory cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and aak-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; metformin; and Sirolimus based on RNA-seq and microarray studies. Human DHRS1 enables carbonyl reductase (NADPH) activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; NAD(P)-binding domain superfamily; and short chain dehydrogenase. Is an ortholog of human DHRS1 (dehydrogenase/reductase 1). WB:WBGene00019111 F59E11.5 Predicted to be located in membrane. WB:WBGene00019112 F59E11.6 Enriched in Z1.p; Z4.a; male distal tip cell; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Tunicamycin; multi-walled carbon nanotube; and glycine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00019113 F59E11.7 Predicted to be located in membrane. Expressed in AVG. WB:WBGene00019114 nhr-194 Expressed in amphid neurons; ciliated neurons; head neurons; and sensory neurons. WB:WBGene00019115 nhr-195 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00019116 nhr-143 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00019117 nhr-144 Enriched in Z1.p; Z4.a; intestine; male distal tip cell; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and daf-12 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; levamisole; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00019118 F59E12.1 Predicted to be part of NuA4 histone acetyltransferase complex. Is an ortholog of human BRD8 (bromodomain containing 8). WB:WBGene00019119 F59E12.3 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00019120 npl-4.1 Predicted to enable ubiquitin binding activity and ubiquitin protein ligase binding activity. Involved in positive regulation of protein localization to nucleus. Located in nucleus. Part of VCP-NPL4-UFD1 AAA ATPase complex. Is an ortholog of human NPLOC4 (NPL4 homolog, ubiquitin recognition factor). WB:WBGene00019121 npl-4.2 Predicted to enable ubiquitin binding activity and ubiquitin protein ligase binding activity. Involved in ER-associated misfolded protein catabolic process and embryo development. Located in nucleus. Part of VCP-NPL4-UFD1 AAA ATPase complex. Is an ortholog of human NPLOC4 (NPL4 homolog, ubiquitin recognition factor). WB:WBGene00019122 F59E12.6 Predicted to enable cysteine-type deubiquitinase activity and proteasome binding activity. Predicted to be involved in regulation of proteasomal protein catabolic process. WB:WBGene00019123 F59E12.8 Predicted to be located in membrane. WB:WBGene00019124 F59E12.9 Enriched in germ line; hypodermis; neurons; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019125 ddl-1 Involved in cytoplasmic sequestering of protein and determination of adult lifespan. Located in cytoplasm. Expressed in body wall musculature; neurons; pharynx; spermatheca; and vulval muscle. Is an ortholog of human WASHC3 (WASH complex subunit 3). WB:WBGene00019126 sam-4 Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including multicellular organismal reproductive process; positive regulation of anterograde synaptic vesicle transport; and positive regulation of pharyngeal pumping. Located in synaptic vesicle membrane. Expressed in nerve ring. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Is an ortholog of human BORCS5 (BLOC-1 related complex subunit 5). WB:WBGene00019127 cgt-3 Predicted to enable ceramide glucosyltransferase activity. Involved in several processes, including glucosylceramide biosynthetic process; regulation of mesodermal cell fate specification; and regulation of protein localization to basolateral plasma membrane. Located in plasma membrane. Expressed in several structures, including germ line; pharyngeal muscle cell; pharyngeal-intestinal valve; rectal gland cell; and rectal valve cell. Is an ortholog of human UGCG (UDP-glucose ceramide glucosyltransferase). WB:WBGene00019128 F59G1.4 Predicted to be involved in cilium assembly. Predicted to be located in centriole; ciliary basal body; and ciliary tip. Expressed in amphid neurons; head ganglion; inner labial neurons; and phasmid neurons. Human ortholog(s) of this gene implicated in Joubert syndrome 30. Is an ortholog of human ARMC9 (armadillo repeat containing 9). WB:WBGene00019129 F59G1.8 Enriched in ABplpppapa; ABprpppapa; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00019130 gbas-1 Enables G-protein alpha-subunit binding activity and guanyl-nucleotide exchange factor activity. Involved in small GTPase mediated signal transduction. Expressed in several structures, including GLR; coelomocyte; distal tip cell; intestine; and neurons. WB:WBGene00019131 bath-12 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including glp-1; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00019132 bath-19 Enriched in several structures, including ABalapppaa; I5 neuron; cholinergic neurons; germ line; and germline precursor cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00019133 F59H6.2 Enriched in NSM and germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019134 F59H6.3 Enriched in germ line; intestine; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00019135 math-32 Enriched in NSM; body wall muscle cell; germ line; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including hydrogen sulfide; methylmercuric chloride; and paraquat based on microarray and RNA-seq studies. WB:WBGene00019136 F59H6.5 No description available WB:WBGene00019137 ceh-85 Expressed in several structures, including head muscle; intestine; neurons; somatic nervous system; and vulval muscle. WB:WBGene00019138 bath-21 Enriched in I5 neuron; cholinergic neurons; germ line; germline precursor cell; and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including daf-2; hsf-1; and elt-2 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including rotenone; antimycin; and Ag nanoparticles based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00019139 bath-1 Enriched in AVHL; AVHR; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00019140 bath-3 Enriched in several structures, including ABplapaaaap; ABprapaaaap; AIM; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00019141 bath-5 Enriched in ABalaaaala; ABalaapaaa; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00019142 btb-4 Enriched in AFD; AVE; body wall muscle cell; germ line; and germline precursor cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00019143 H01M10.1 Enriched in several structures, including ABplpppaaa; ABplpppapa; coelomocyte; excretory gland cell; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; Doxycycline; and paraquat based on microarray and RNA-seq studies. WB:WBGene00019144 H01M10.2 Enriched in several structures, including amphid sheath cell; male distal tip cell; neurons; rectal epithelial cell; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; sir-2.1; and dpy-7 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00019145 H02F09.2 Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Cadmium Chloride; Ag nanoparticles; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00019146 H02F09.3 Predicted to be located in membrane. WB:WBGene00019147 H02F09.4 No description available WB:WBGene00019148 H03E18.1 Enriched in epithelial cell; hypodermis; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-seven chemicals including methylmercury hydroxide; 1-methylnicotinamide; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN/Apple domain; PAN domain; and Phosphorylation site. WB:WBGene00019149 H03E18.2 Predicted to be located in membrane. WB:WBGene00019150 H04J21.1 Enriched in amphid neurons and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including tryptophan; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function and Domain of unknown function WSN. WB:WBGene00019151 pck-3 Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Predicted to be located in cytosol. Expressed in excretory cell. WB:WBGene00019152 nspb-6 Enriched in arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by sixteen chemicals including hydrogen sulfide; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1459) and Protein of unknown function DUF1459. WB:WBGene00019153 H04M03.3 Predicted to enable oxidoreductase activity. WB:WBGene00019154 glf-1 Enables UDP-galactopyranose mutase activity. Involved in polysaccharide biosynthetic process. Located in cytoplasm. Expressed in hypodermis; muscle cell; and neurons. WB:WBGene00019155 H04M03.11 Predicted to be located in membrane. WB:WBGene00019156 H04M03.12 Predicted to be located in membrane. WB:WBGene00019157 H05C05.1 Predicted to enable nucleic acid binding activity. WB:WBGene00019158 H05C05.2 Enriched in body wall muscle cell; coelomocyte; germ line; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including hsf-1; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Zidovudine; paraquat; and Hydrolyzable Tannins based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019159 H05C05.3 Enriched in intestine based on microarray studies. Is affected by several genes including clk-1; pgl-1; and lin-35 based on microarray and RNA-seq studies. WB:WBGene00019160 nlp-49 Predicted to be involved in neuropeptide signaling pathway. Expressed in nerve ring neurons. WB:WBGene00019162 eif-1.A Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Expressed in head and tail. Is an ortholog of human EIF1AX (eukaryotic translation initiation factor 1A X-linked) and EIF1AY (eukaryotic translation initiation factor 1A Y-linked). WB:WBGene00019163 ubxn-6 Predicted to be located in cytoplasm. Expressed in pharynx. Is an ortholog of human UBXN6 (UBX domain protein 6). WB:WBGene00019164 H06H21.8 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00019165 mpz-4 Enriched in NSM; germ line; and in male based on RNA-seq and tiling array studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PDZ domain; Uncharacterized protein T15H9.4-like; and PDZ superfamily. WB:WBGene00019166 tat-2 Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Involved in sterol metabolic process. Predicted to be located in plasma membrane and trans-Golgi network. Expressed in several structures, including excretory system; gonad; pharynx; rectal gland cell; and vulva. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 1; intrahepatic cholestasis of pregnancy 1; and progressive familial intrahepatic cholestasis 1. Is an ortholog of human ATP8B4 (ATPase phospholipid transporting 8B4 (putative)). WB:WBGene00019167 ccep-135 Enriched in several structures, including ABalaaaala; germ line; head mesodermal cell; lateral ganglion; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eight chemicals including D-glucose; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019168 H06I04.3 Predicted to enable rRNA (guanine) methyltransferase activity and rRNA (uridine-2'-O-)-methyltransferase activity. Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and rRNA methylation. Predicted to be located in nucleolus. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3). WB:WBGene00019169 H06I04.5 Enriched in several structures, including ABalpppppa; ABalppppppa; NSM; amphid neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including hydrogen sulfide; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00019170 H06I04.6 Enriched in MSaaaaapa; MSpaaapa; muscle cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; rotenone; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: CX module and Domain of unknown function CX. WB:WBGene00019171 fipr-29 Enriched in ABprpapppa and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; elt-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019174 H09G03.1 Enriched in several structures, including CAN; GABAergic neurons; excretory system; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00019176 H10D12.2 Enriched in male-specific anatomical entity and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; Zidovudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00019177 H10D18.1 Enriched in neurons; rectal epithelial cell; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019178 scl-12 Predicted to be located in extracellular space. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00019179 scl-13 Predicted to be located in extracellular space. Is an ortholog of human PI15 (peptidase inhibitor 15). WB:WBGene00019180 H10D18.5 Enriched in several structures, including body wall musculature; enteric muscle; head mesodermal cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and sek-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00019181 H10D18.6 Enriched in intestine and sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; cat-2; and mex-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019182 H10E21.1 Predicted to be located in membrane. Expressed in intestine; rectal valve cell; tail hypodermis; and tail spike. WB:WBGene00019183 npr-30 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00019184 H10E21.4 Predicted to enable calcium ion binding activity. WB:WBGene00019185 H10E21.5 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Is an ortholog of human RNF150 (ring finger protein 150). WB:WBGene00019186 fbxb-58 Is affected by several genes including eat-2; sir-2.1; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by dafa#1 and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019187 H11E01.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00019188 H11E01.3 Enriched in body wall musculature; intestine; neurons; and pharyngeal muscle cell based on microarray; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including stavudine; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Glutamate-rich protein 3. WB:WBGene00019189 H11L12.1 Enriched in germ line; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019190 H12I13.1 Predicted to enable ATP binding activity; cysteine-type deubiquitinase activity; and protein kinase activity. Predicted to be involved in proteolysis. WB:WBGene00019192 H12I13.3 Is affected by rsr-2; prg-1; and drh-3 based on tiling array and RNA-seq studies. Is affected by Progesterone; Atrazine; and allantoin based on microarray studies. WB:WBGene00019193 H12I13.5 Is affected by several genes including eat-2; mex-3; and ubc-9 based on microarray and RNA-seq studies. Is affected by Tunicamycin; allantoin; and Sirolimus based on microarray studies. WB:WBGene00019194 H12I13.6 Enriched in arc ant V; germ line; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Ethanol; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019195 H14A12.1 No description available WB:WBGene00019196 H14A12.3 Predicted to be located in nuclear envelope. Predicted to be part of RAVE complex. Human ortholog(s) of this gene implicated in Kohlschutter-Tonz syndrome. Is an ortholog of human ROGDI (rogdi atypical leucine zipper). WB:WBGene00019197 H14A12.5 Enriched in I5 neuron; cholinergic neurons; head mesodermal cell; intestine; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Lithium Chloride; rotenone; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00019198 strm-1 Enables S-adenosylmethionine-dependent methyltransferase activity. Involved in macromolecule methylation and regulation of dauer larval development. Predicted to be located in endoplasmic reticulum. Expressed in hypodermis and pharynx. WB:WBGene00019199 H14E04.2 Predicted to enable catalytic activity. Predicted to be involved in nucleoside metabolic process. WB:WBGene00019200 H14E04.3 Predicted to be located in membrane. WB:WBGene00019202 H14N18.2 Predicted to be located in membrane. WB:WBGene00019203 ttr-47 Predicted to be located in cell surface and extracellular region. WB:WBGene00019204 H14N18.4 Predicted to enable glutathione hydrolase activity. Predicted to be involved in glutathione catabolic process. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including biliary atresia; diabetes mellitus (multiple); and liver disease (multiple). Is an ortholog of human GGT1 (gamma-glutamyltransferase 1); GGT2P (gamma-glutamyltransferase 2, pseudogene); and GGT3P (gamma-glutamyltransferase 3 pseudogene). WB:WBGene00019205 kcc-2 Enables potassium:chloride symporter activity. Involved in chloride transport; potassium ion transport; and regulation of GABAergic synaptic transmission. Predicted to be located in plasma membrane. Expressed in body wall musculature; egg-laying apparatus; hermaphrodite distal tip cell; intestine; and neurons. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease; agenesis of the corpus callosum with peripheral neuropathy; and epilepsy (multiple). Is an ortholog of human SLC12A4 (solute carrier family 12 member 4); SLC12A5 (solute carrier family 12 member 5); and SLC12A7 (solute carrier family 12 member 7). WB:WBGene00019207 fdgt-1 Predicted to enable hexose transmembrane transporter activity. Involved in glucose transmembrane transport. Predicted to be located in membrane. Expressed in hypodermis; intestinal cell; muscle cell; neurons; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Hirschsprung's disease; artery disease (multiple); and brain disease (multiple). Is an ortholog of human SLC2A14 (solute carrier family 2 member 14) and SLC2A3 (solute carrier family 2 member 3). WB:WBGene00019208 lips-14 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including hydrogen sulfide; D-glucose; and bisphenol A based on microarray and RNA-seq studies. WB:WBGene00019209 emc-1 Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of EMC complex. Human ortholog(s) of this gene implicated in cerebellar atrophy, visual impairment, and psychomotor retardation. Is an ortholog of human EMC1 (ER membrane protein complex subunit 1). WB:WBGene00019210 H18N23.1 No description available WB:WBGene00019211 H18N23.2 Predicted to enable glycogen binding activity and protein phosphatase 1 binding activity. Predicted to be involved in regulation of glycogen biosynthetic process. Predicted to be part of protein phosphatase type 1 complex. Is an ortholog of human PPP1R3B (protein phosphatase 1 regulatory subunit 3B). WB:WBGene00019212 zmp-2 Enables metallopeptidase activity. Involved in several processes, including determination of adult lifespan; regulation of metabolic process; and regulation of transport. Predicted to be located in extracellular space. Expressed in several structures, including anal region; body wall musculature; gonad; tail; and vulval muscle. Is an ortholog of human MMP23B (matrix metallopeptidase 23B). WB:WBGene00019213 H20E11.1 Predicted to be involved in innate immune response. Predicted to be located in membrane. WB:WBGene00019214 H20E11.2 Predicted to be involved in innate immune response. WB:WBGene00019215 H20E11.3 Involved in innate immune response. WB:WBGene00019216 H20J04.1 Predicted to be located in membrane. WB:WBGene00019217 athp-2 Predicted to enable DNA binding activity. Predicted to be involved in positive regulation of DNA replication; regulation of DNA-templated transcription; and regulation of heterochromatin formation. Predicted to be located in nuclear chromosome. Predicted to be part of ACF complex and CHRAC. Is an ortholog of human BAZ1A (bromodomain adjacent to zinc finger domain 1A). WB:WBGene00019218 madf-3 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. WB:WBGene00019219 H20J04.4 Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleus. Is an ortholog of human DDX49 (DEAD-box helicase 49). WB:WBGene00019220 pfd-2 Predicted to enable protein folding chaperone. Predicted to be involved in protein folding. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Is an ortholog of human PFDN2 (prefoldin subunit 2). WB:WBGene00019221 H20J04.6 Predicted to be located in membrane. Is an ortholog of human TMEM222 (transmembrane protein 222). WB:WBGene00019222 H20J04.7 Predicted to be located in membrane. WB:WBGene00019224 gnrr-5 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00019225 bgal-2 Predicted to enable beta-galactosidase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in vacuole. Is an ortholog of human GLB1L (galactosidase beta 1 like). WB:WBGene00019226 idpp-6 Enriched in Y cell; g2; and neurons based on tiling array; microarray; and single-cell RNA-seq studies. Is affected by several genes including eat-2; daf-1; and set-2 based on RNA-seq; tiling array; and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019227 sgca-1 Predicted to enable calcium ion binding activity. Located in striated muscle dense body. Expressed in anal depressor muscle; anal sphincter muscle; body wall musculature; and vulval muscle. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2D; myoclonic dystonia 11; and stomach cancer. Is an ortholog of human SGCA (sarcoglycan alpha) and SGCE (sarcoglycan epsilon). WB:WBGene00019228 H23L24.1 Predicted to be located in membrane. WB:WBGene00019229 ipla-5 Predicted to enable hydrolase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00019230 ttll-11 Enables tubulin-glutamic acid ligase activity. Involved in response to hermaphrodite contact. Predicted to be located in cilium. Expressed in ciliated neurons and in male. Is an ortholog of human TTLL11 (tubulin tyrosine ligase like 11). WB:WBGene00019231 H23L24.4 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00019232 ugt-13 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1); UGT3A2 (UDP glycosyltransferase family 3 member A2); and UGT8 (UDP glycosyltransferase 8). WB:WBGene00019233 ugt-14 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1); UGT3A2 (UDP glycosyltransferase family 3 member A2); and UGT8 (UDP glycosyltransferase 8). WB:WBGene00019234 ugt-8 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00019235 ugt-67 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00019236 H23N18.5 Predicted to enable phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion and phospholipid metabolic process. WB:WBGene00019237 wdr-62 Predicted to enable kinase activity. Predicted to be involved in centriole replication. Predicted to be located in mitotic spindle. Human ortholog(s) of this gene implicated in several diseases, including nephronophthisis 20; polymicrogyria; and primary autosomal recessive microcephaly 2 with or without cortical malformations. Is an ortholog of human WDR62 (WD repeat domain 62). WB:WBGene00019239 H24K24.2 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00019240 adh-5 Predicted to enable S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; and zinc ion binding activity. Predicted to be involved in formaldehyde catabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including AMED syndrome; alcohol use disorder; and late onset Parkinson's disease. Is an ortholog of human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide). WB:WBGene00019241 trm-2A Predicted to enable RNA binding activity; RNA methyltransferase activity; and S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in RNA methylation and RNA processing. Is an ortholog of human TRMT2A (tRNA methyltransferase 2 homolog A). WB:WBGene00019242 srbc-40 Predicted to be located in membrane. WB:WBGene00019243 fbxb-72 Enriched in several structures, including ABalppappa; ABarappppa; ABplpppaaa; AVK; and amphid neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019244 H25P19.1 Enriched in several structures, including ABaraapapaa; germ line; intestinal muscle; mechanosensory neurons; and rectal muscle based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including rotenone; mianserin; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00019245 sacy-1 Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in cytoplasm and nucleus. Expressed in hypodermis; intestine; and somatic cell. Human ortholog(s) of this gene implicated in myeloproliferative neoplasm. Is an ortholog of human DDX41 (DEAD-box helicase 41). WB:WBGene00019246 rpb-5 Predicted to enable DNA binding activity and DNA-directed 5'-3' RNA polymerase activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase I; transcription by RNA polymerase II; and transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Is an ortholog of human POLR2E (RNA polymerase II, I and III subunit E). WB:WBGene00019247 syp-4 Predicted to be involved in meiotic cell cycle. Located in central element. WB:WBGene00019248 H27M09.5 Predicted to be located in membrane. WB:WBGene00019249 hrpa-2 Predicted to enable mRNA binding activity. Predicted to be located in nucleus. WB:WBGene00019250 H28G03.2 Enriched in several structures, including ABalappaap; ABalpppapa; ABpraaaapa; germ line; and neurons based on microarray; RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and npr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by four chemicals including silicon dioxide nanoparticle; Quercetin; and single-walled carbon nanotube based on microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019251 H28G03.3 Enriched in AFD; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and nhr-25 based on RNA-seq and microarray studies. Is affected by resveratrol and adsorbable organic bromine compound based on microarray studies. WB:WBGene00019252 H28G03.4 No description available WB:WBGene00019253 H31G24.1 Enriched in male-specific anatomical entity; sensory neurons; and tail hypodermis based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including csr-1; mex-3; and spr-5 based on microarray and RNA-seq studies. Is affected by manganese chloride; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00019254 H31G24.3 Enriched in Cappppv; Cpppppv; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00019255 H32C10.1 Predicted to be involved in glycerophospholipid biosynthetic process. Predicted to be located in mitochondrion. Is an ortholog of human HDHD5 (haloacid dehalogenase like hydrolase domain containing 5). WB:WBGene00019257 dhhc-13 Predicted to enable palmitoyltransferase activity. Predicted to be located in Golgi membrane. Is an ortholog of human ZDHHC13 (zinc finger DHHC-type palmitoyltransferase 13). WB:WBGene00019259 usp-4 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in proteolysis. Human ortholog(s) of this gene implicated in chronic myeloid leukemia. Is an ortholog of human USP4 (ubiquitin specific peptidase 4). WB:WBGene00019260 H34I24.1 Enriched in AFD; GABAergic neurons; body wall muscle cell; germ line; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00019261 H34I24.2 Enriched in OLL; PVD; head mesodermal cell; intestine; and pharyngeal muscle cell based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty chemicals including manganese chloride; mianserin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019262 dmsr-12 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00019263 H35B03.1 Enriched in MSpppaaa; excretory cell; head mesodermal cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019264 H35B03.2 Predicted to enable RNA binding activity. Predicted to be involved in tRNA processing. Predicted to be part of nucleolar ribonuclease P complex. Is an ortholog of human RPP30 (ribonuclease P/MRP subunit p30). WB:WBGene00019265 H35N09.1 Enriched in coelomocyte; head mesodermal cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00019266 H35N09.2 Predicted to enable nucleic acid binding activity. WB:WBGene00019267 H39E20.1 Enriched in germ line based on RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and nhr-49 based on microarray and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; silicon dioxide nanoparticle; and Diazinon based on microarray studies. WB:WBGene00019268 H41C03.1 Enriched in several structures, including ABarpaapap; ABarpaappa; anterior hypodermis; mechanosensory neurons; and rectal epithelial cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including bisphenol A; TPEN; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: CRAL-TRIO lipid binding domain; CRAL/TRIO, N-terminal domain superfamily; CRAL-TRIO lipid binding domain superfamily; and CRAL/TRIO domain. WB:WBGene00019269 H41C03.2 Predicted to be involved in lipid metabolic process. WB:WBGene00019270 H41C03.3 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00019272 H42K12.3 Enriched in hypodermis; sensory neurons; and ventral cord blast cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-nine chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PAN/Apple domain; PAN domain; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00019273 H43E16.1 Predicted to be located in membrane. WB:WBGene00019274 H43I07.1 Predicted to be involved in regulation of lipid metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 3 and optic atrophy 3. Is an ortholog of human OPA3 (outer mitochondrial membrane lipid metabolism regulator OPA3). WB:WBGene00019275 rpac-40 Predicted to enable DNA-directed 5'-3' RNA polymerase activity and protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase I and transcription by RNA polymerase III. Predicted to be part of RNA polymerase I complex and RNA polymerase III complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 3 and hypomyelinating leukodystrophy 11. Is an ortholog of human POLR1C (RNA polymerase I and III subunit C). WB:WBGene00019276 algn-5 Predicted to enable dolichyl-phosphate beta-glucosyltransferase activity. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in polycystic kidney disease. Is an ortholog of human ALG5 (ALG5 dolichyl-phosphate beta-glucosyltransferase). WB:WBGene00019277 sgcb-1 Predicted to be involved in muscle organ development. Predicted to be located in sarcolemma. Predicted to be part of sarcoglycan complex. Expressed in body wall musculature; enteric muscle; neurons; seam cell; and vulval muscle. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2E. Is an ortholog of human SGCB (sarcoglycan beta). WB:WBGene00019278 K01A2.3 Expressed in intestine. WB:WBGene00019279 K01A2.4 Predicted to be located in membrane. WB:WBGene00019280 K01A2.5 Predicted to enable hydrolase activity. Expressed in hypodermis. Is an ortholog of human BPHL (biphenyl hydrolase like). WB:WBGene00019281 K01A2.6 Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Alovudine; and adsorbable organic bromine compound based on RNA-seq and microarray studies. WB:WBGene00019282 mps-2 Enables potassium channel regulator activity. Involved in regulation of chemotaxis and regulation of potassium ion transport. Predicted to be located in membrane. Expressed in several structures, including body wall musculature; enteric muscle; intestine; lateral ganglion; and rectal muscle. WB:WBGene00019283 K01A2.9 Predicted to be located in membrane. WB:WBGene00019284 K01A2.10 Enriched in several structures, including ABalapapap; ABalapppap; excretory cell; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Mercuric Chloride; indole; and 4-bromodiphenyl ether based on microarray and RNA-seq studies. Human CCDC92 enables identical protein binding activity. Is predicted to encode a protein with the following domains: Coiled-coil domain-containing protein 74A/74B/92 and Phosphorylation site. Is an ortholog of human CCDC92 (coiled-coil domain containing 92). WB:WBGene00019285 cbn-1 Predicted to enable calcium ion binding activity. WB:WBGene00019286 K01A12.2 Enriched in neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and fog-2 based on microarray and RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019287 K01A12.3 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00019288 K02A2.1 Predicted to enable hydrolase activity. WB:WBGene00019289 kcc-3 Predicted to enable potassium:chloride symporter activity. Involved in microvillus organization. Located in apical plasma membrane. Expressed in amphid sheath cell; head; phasmid sheath cell; and tail. WB:WBGene00019290 K02A2.5 Enriched in germline precursor cell; intestine; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including Alovudine; glycine; and Cadmium Chloride based on RNA-seq and microarray studies. WB:WBGene00019291 K02A2.6 No description available WB:WBGene00019292 K02A6.1 Enriched in AFD and FLP based on microarray and RNA-seq studies. Is affected by clk-1; hrde-1; and drh-3 based on microarray and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00019293 K02A6.2 Enriched in arcade cell; neurons; pharyngeal-intestinal valve cell; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019294 K02A6.3 Enriched in several structures, including dopaminergic neurons; head mesodermal cell; intestinal muscle; mechanosensory neurons; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Ethanol; levamisole; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily; F-box-like; F-box-like domain superfamily; and F-box domain. WB:WBGene00019295 pfkb-1.2 Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to be located in cytosol. Is an ortholog of several human genes including PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1); PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2); and PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3). WB:WBGene00019296 mcu-1 Enables identical protein binding activity. Involved in several processes, including calcium import into the mitochondrion; mitochondrial calcium ion homeostasis; and protein homooligomerization. Predicted to be located in mitochondrial inner membrane. Predicted to be part of uniplex complex. Is an ortholog of human MCU (mitochondrial calcium uniporter). WB:WBGene00019297 K02B2.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Tunicamycin; silicon dioxide nanoparticle; and resveratrol based on microarray studies. WB:WBGene00019298 pnp-1 Predicted to enable purine-nucleoside phosphorylase activity. Involved in innate immune response. Predicted to be located in cytoplasm. Expressed in epithelial cell and head neurons. Human ortholog(s) of this gene implicated in purine nucleoside phosphorylase deficiency and purine-pyrimidine metabolic disorder. Is an ortholog of human PNP (purine nucleoside phosphorylase). WB:WBGene00019299 snai-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in PHAL; PHAR; PHBL; PHBR; and amphid neurons. Human ortholog(s) of this gene implicated in colorectal cancer; oral mucosa leukoplakia; and piebaldism. Is an ortholog of human SNAI1 (snail family transcriptional repressor 1) and SNAI2 (snail family transcriptional repressor 2). WB:WBGene00019300 swt-1 Enables sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport. Located in Golgi apparatus and plasma membrane. Is an ortholog of human SLC50A1 (solute carrier family 50 member 1). WB:WBGene00019301 K02D10.1 Predicted to enable metal ion binding activity and phosphatase activity. Predicted to be located in mitochondrion. Is an ortholog of human NIPSNAP1 (nipsnap homolog 1) and NIPSNAP2 (nipsnap homolog 2). WB:WBGene00019302 K02D10.2 Enriched in germ line and neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by paraquat and Colistin based on RNA-seq and microarray studies. WB:WBGene00019303 K02D10.3 Enriched in several structures, including g1P; germ line; head mesodermal cell; intestinal muscle; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; unc-30; and met-2 based on RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019304 K02D10.4 Enriched in body wall muscle cell; neurons; retrovesicular ganglion; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019305 snap-29 Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in intracellular protein transmembrane transport; ovulation; and secretion. Located in apical plasma membrane and recycling endosome. Expressed in several structures, including coelomocyte; excretory canal; gland cell; hermaphrodite somatic gonadal cell; and vulva. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in CEDNIK syndrome. Is an ortholog of human SNAP29 (synaptosome associated protein 29). WB:WBGene00019306 K02E7.1 Enriched in Y cell; germline precursor cell; and tail hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00019307 K02E7.2 No description available WB:WBGene00019308 K02E7.3 No description available WB:WBGene00019309 K02E7.4 Is affected by several genes including eat-2; aak-2; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Human TNFAIP1 Contributes to ubiquitin-protein transferase activity. Human TNFAIP1 enables identical protein binding activity and small GTPase binding activity. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00019310 K02E7.5 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including 1-methylnicotinamide; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00019311 K02E7.6 Enriched in several structures, including Z1.p; Z4.a; intestine; male distal tip cell; and mechanosensory neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty chemicals including methylmercury hydroxide; 1-methylnicotinamide; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00019312 K02E7.7 Enriched in ABplpaaaap; ABprpaaaap; B cell; MSpaaapa; and lumbar neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00019313 btb-10 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00019314 K02E7.10 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; Huntington's disease; and cerebrovascular disease (multiple). Is an ortholog of human CTSH (cathepsin H); CTSK (cathepsin K); and CTSS (cathepsin S). WB:WBGene00019315 K02E7.11 Predicted to be located in membrane. WB:WBGene00019316 K02E7.12 Enriched in body wall muscle cell; body wall musculature; coelomocyte; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00019317 rabr-1 Predicted to enable GTPase activity. Predicted to be involved in protein localization; regulation of exocytosis; and vesicle-mediated transport. Predicted to be located in cytoplasmic vesicle and plasma membrane. WB:WBGene00019318 K02E10.4 Predicted to be located in membrane. WB:WBGene00019319 K02E10.5 Predicted to be located in membrane. WB:WBGene00019320 K02E10.6 Enriched in several structures, including interfacial epithelial cell; male distal tip cell; pharyngeal cell; rectal gland cell; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; sesamin; and stavudine based on microarray and RNA-seq studies. WB:WBGene00019321 K02E10.7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in mitotic DNA damage checkpoint signaling. Predicted to be located in cytoplasm and nucleus. WB:WBGene00019322 ahcy-1 Predicted to enable adenosylhomocysteinase activity. Predicted to be involved in S-adenosylhomocysteine catabolic process and S-adenosylmethionine cycle. Predicted to be located in cytosol. Expressed in head. Human ortholog(s) of this gene implicated in hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase. Is an ortholog of human AHCY (adenosylhomocysteinase). WB:WBGene00019323 teg-4 Predicted to enable U2 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP. Is an ortholog of human SF3B3 (splicing factor 3b subunit 3). WB:WBGene00019324 K02F2.5 Enriched in head mesodermal cell; neurons; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-7 based on microarray; proteomic; and RNA-seq studies. Is affected by thirteen chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019326 K02F3.2 Predicted to enable acidic amino acid transmembrane transporter activity; calcium ion binding activity; and identical protein binding activity. Predicted to be involved in L-glutamate transmembrane transport; aspartate transmembrane transport; and malate-aspartate shuttle. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in autism spectrum disorder (multiple); citrullinemia (multiple); and developmental and epileptic encephalopathy 39. Is an ortholog of human SLC25A12 (solute carrier family 25 member 12). WB:WBGene00019327 zip-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to bacterium and positive regulation of macromolecule metabolic process. Predicted to be located in nucleus. Expressed in pharynx. WB:WBGene00019328 clec-149 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including acquired immunodeficiency syndrome; bronchopulmonary dysplasia; and tuberculosis (multiple). Is an ortholog of human CD209 (CD209 molecule) and FCER2 (Fc epsilon receptor II). WB:WBGene00019329 ceeh-1 Enables epoxide hydrolase activity. Involved in cellular lipid metabolic process. Predicted to be located in membrane. Is an ortholog of human EPHX3 (epoxide hydrolase 3) and EPHX4 (epoxide hydrolase 4). WB:WBGene00019331 dos-3 Predicted to enable Notch binding activity. Predicted to be involved in positive regulation of Notch signaling pathway. Predicted to be located in extracellular space. WB:WBGene00019332 K02F3.9 Enriched in body wall muscle cell and muscle cell based on tiling array and microarray studies. Is affected by several genes including skn-1; glp-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq; microarray; and proteomic studies. WB:WBGene00019333 moma-1 Predicted to be involved in cristae formation. Located in mitochondrial outer membrane. Is an ortholog of human APOOL (apolipoprotein O like). WB:WBGene00019334 K02F3.12 Predicted to enable 3'-5' DNA helicase activity and four-way junction helicase activity. Predicted to be involved in DNA unwinding involved in DNA replication and double-strand break repair via homologous recombination. Predicted to be located in chromosome and cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and pancreatic cancer. Is an ortholog of human RECQL (RecQ like helicase). WB:WBGene00019335 K02F6.1 Predicted to enable enzyme binding activity; nucleic acid binding activity; and zinc ion binding activity. Predicted to be located in cytoplasm. WB:WBGene00019337 K02F6.3 Predicted to be located in membrane. WB:WBGene00019338 K02F6.4 Predicted to be located in membrane. WB:WBGene00019339 K02F6.5 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00019340 K02F6.6 Is affected by several genes including daf-2; pgl-1; and glh-1 based on microarray and RNA-seq studies. WB:WBGene00019341 K02F6.7 Enriched in ADEshL; ADEshR; NSM; germ line; and hypodermis based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq; proteomic; and microarray studies. WB:WBGene00019342 K02F6.8 Predicted to be involved in protein homooligomerization. Is an ortholog of human KCTD10 (potassium channel tetramerization domain containing 10); KCTD13 (potassium channel tetramerization domain containing 13); and TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00019343 nep-18 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00019344 dhhc-10 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Expressed in several structures, including enteric muscle; intestine; pharynx; spermatheca; and ventral nerve cord. Is an ortholog of human ZDHHC22 (zinc finger DHHC-type palmitoyltransferase 22). WB:WBGene00019345 tmem-135 Acts upstream of or within several processes, including determination of adult lifespan; positive regulation of lipid storage; and positive regulation of mitochondrial membrane potential. Located in cytoplasm and lipid droplet. Expressed in epithelial system and pharynx. Is an ortholog of human TMEM135 (transmembrane protein 135). WB:WBGene00019346 K02G10.5 Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. WB:WBGene00019347 mbl-1 Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleus. Expressed in excretory cell; neurons; and tail. Used to study myotonic disease. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human MBNL3 (muscleblind like splicing regulator 3). WB:WBGene00019348 K02H11.4 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00019349 trx-5 Predicted to be involved in photoreceptor cell maintenance and sensory perception. Is an ortholog of human NXNL2 (nucleoredoxin like 2). WB:WBGene00019350 K02H11.9 Is affected by several genes including hpl-2; his-24; and drh-3 based on RNA-seq and microarray studies. Is affected by six chemicals including Rifampin; Sirolimus; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019351 lron-7 Predicted to enable chromatin binding activity. Predicted to be involved in chromatin organization and establishment of protein localization to chromatin. Predicted to be located in membrane. Predicted to be part of nuclear origin of replication recognition complex. Expressed in head. Is an ortholog of human OPTC (opticin). WB:WBGene00019352 K03A1.4 Predicted to enable calcium ion binding activity and enzyme regulator activity. Expressed in head neurons and tail neurons. WB:WBGene00019353 K03B4.1 Predicted to enable serine-tRNA ligase activity and tRNA binding activity. Predicted to be involved in mitochondrial seryl-tRNA aminoacylation. Predicted to be located in mitochondrion. WB:WBGene00019354 K03B4.2 Enriched in germ line; neurons; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and gld-1 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including rotenone; Cry5B; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019355 K03B4.4 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00019356 K03B4.6 Predicted to be located in membrane. WB:WBGene00019357 cpg-8 Enriched in several structures, including ABarpaapap; g1P; germ line; neurons; and spermatheca based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and let-60 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; Mercuric Chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019360 neto-1 Predicted to be located in membrane. Is an ortholog of human NETO1 (neuropilin and tolloid like 1) and NETO2 (neuropilin and tolloid like 2). WB:WBGene00019361 clik-3 Enriched in several structures, including ABaraapapaa; alimentary muscle; distal tip cell; head mesodermal cell; and neurons based on RNA-seq; tiling array; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-7 based on RNA-seq; proteomic; and microarray studies. Is affected by fifteen chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Calponin repeat and Calponin family repeat. WB:WBGene00019362 cdk-2 Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Involved in several processes, including pseudocleavage; regulation of mitotic cell cycle; and regulation of protein localization. Part of chromatin. WB:WBGene00019364 mksr-1 Involved in several processes, including determination of adult lifespan; larval foraging behavior; and non-motile cilium assembly. Located in ciliary transition zone. Expressed in amphid neurons; ciliated neurons; and sensory neurons. Used to study ciliopathy and nephronophthisis. Human ortholog(s) of this gene implicated in Joubert syndrome 27 and Meckel syndrome. Is an ortholog of human B9D1 (B9 domain containing 1). WB:WBGene00019365 rei-2 Predicted to enable protein kinase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm. Is an ortholog of human SH3BP5 (SH3 domain binding protein 5) and SH3BP5L (SH3 binding domain protein 5 like). WB:WBGene00019366 K03F8.1 No description available WB:WBGene00019367 K03H6.1 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00019368 txt-4 Predicted to be involved in lipid metabolic process. WB:WBGene00019369 K03H6.4 Predicted to be located in membrane. WB:WBGene00019370 K03H6.5 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00019371 K03H9.1 Enriched in neurons based on RNA-seq studies. Is affected by hpl-2 and rsr-2 based on tiling array studies. WB:WBGene00019372 K03H9.3 Enriched in several structures, including FLP; anterior hypodermis; interfacial epithelial cell; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including multi-walled carbon nanotube; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00019373 K04A8.1 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00019374 K04A8.2 Enriched in excretory gland cell; g1; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including atfs-1; drh-3; and cyc-1 based on microarray and RNA-seq studies. Is affected by metformin and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019376 lipl-4 Enables triglyceride lipase activity. Involved in cellular lipid metabolic process; determination of adult lifespan; and positive regulation of macroautophagy. Located in lysosome. Expressed in intestine and seam cell. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). WB:WBGene00019378 K04A8.7 No description available WB:WBGene00019379 K04A8.10 Enriched in head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including tryptophan; methylmercuric chloride; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00019380 K04C2.2 Predicted to enable sequence-specific DNA binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleolus. Is an ortholog of human MYBBP1A (MYB binding protein 1a). WB:WBGene00019381 K04C2.3 Enriched in germ line; intestine; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00019382 K04C2.5 Enriched in AFD and hypodermis based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and lin-4 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including aldicarb; multi-walled carbon nanotube; and Neurotoxins based on microarray and RNA-seq studies. WB:WBGene00019383 K04E7.1 Predicted to be located in membrane. WB:WBGene00019384 K04F1.1 Enriched in NSM; intestine; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; prg-1; and mut-2 based on proteomic; RNA-seq; and microarray studies. Is affected by four chemicals including Tunicamycin; multi-walled carbon nanotube; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00019385 irld-41 Is affected by etr-1 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00019386 irld-42 Enriched in PHB and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including elt-2; clk-1; and csr-1 based on microarray and RNA-seq studies. Is affected by cadmium and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00019387 K04F1.8 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; hpl-2; and his-24 based on tiling array; microarray; and RNA-seq studies. Is affected by dibromoacetic acid based on microarray studies. WB:WBGene00019388 K04F1.9 Enriched in cephalic sheath cell; dopaminergic neurons; germ line; hypodermis; and mechanosensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-eight chemicals including methylmercuric chloride; Mercuric Chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00019389 irld-40 Enriched in PHB and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including elt-2; sir-2.1; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; resveratrol; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00019390 irld-43 Is affected by several genes including hpl-2; drh-3; and hda-2 based on RNA-seq studies. Is affected by resveratrol and dibromoacetic acid based on microarray studies. WB:WBGene00019391 irld-11 Enriched in ASGL; ASGR; and neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including let-60; nhr-49; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Ag nanoparticles and resveratrol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00019392 irld-44 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00019393 irld-45 Enriched in MSpaaapa and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; clk-1; and etr-1 based on RNA-seq and microarray studies. Is affected by cadmium and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00019394 K04F10.1 Predicted to enable RNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 1. Is an ortholog of human ATXN1L (ataxin 1 like). WB:WBGene00019395 K04F10.2 Acts upstream of or within motile cilium assembly. Located in ciliary base. Expressed in ciliated neurons and intestinal cell. Human ortholog(s) of this gene implicated in Joubert syndrome 26. Is an ortholog of human KATNIP (katanin interacting protein). WB:WBGene00019396 K04F10.3 Enriched in several structures, including ABalppppaa; ABpraaapaa; excretory cell; germ line; and interneuron based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and gld-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019397 K04F10.5 No description available WB:WBGene00019399 K04F10.7 Predicted to be located in nuclear speck. Is an ortholog of human FAM76A (family with sequence similarity 76 member A) and FAM76B (family with sequence similarity 76 member B). WB:WBGene00019400 K04G7.1 Expressed in body wall musculature and head neurons. Is predicted to encode a protein with the following domains: Integrase zinc binding domain; Integrase zinc-binding domain; and Phosphorylation site. WB:WBGene00019401 nuo-4 Predicted to enable kinase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in cytoplasm. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 22. Is an ortholog of human NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10). WB:WBGene00019402 syf-2 Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of Prp19 complex; catalytic step 2 spliceosome; and post-mRNA release spliceosomal complex. Is an ortholog of human SYF2 (SYF2 pre-mRNA splicing factor). WB:WBGene00019403 K05B2.2 Expressed in several structures, including head muscle; interfacial epithelial cell; pharyngeal muscle cell; rectal gland cell; and vulva. Human ortholog(s) of this gene implicated in cholangiocarcinoma. Is predicted to encode a protein with the following domains: Ubiquitin-like domain superfamily and N-terminal RASSF family. Is an ortholog of human RASSF7 (Ras association domain family member 7). WB:WBGene00019404 K05B2.4 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in disease of metabolism. Is an ortholog of several human genes including ACOT2 (acyl-CoA thioesterase 2); ACOT4 (acyl-CoA thioesterase 4); and BAAT (bile acid-CoA:amino acid N-acyltransferase). WB:WBGene00019405 K05F1.1 Predicted to be located in membrane. WB:WBGene00019406 acdh-8 Predicted to enable medium-chain-acyl-CoA dehydrogenase activity. Predicted to be involved in medium-chain fatty acid catabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in medium chain acyl-CoA dehydrogenase deficiency. Is an ortholog of human ACADM (acyl-CoA dehydrogenase medium chain). WB:WBGene00019407 lect-2 Predicted to enable metal ion binding activity. Involved in innervation; regulation of dendrite extension; and regulation of dendrite morphogenesis. Located in basement membrane; cell surface; and somatodendritic compartment. Expressed in body wall musculature; coelomocyte; head neurons; and ventral cord neurons. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung adenocarcinoma. Is an ortholog of human LECT2 (leukocyte cell derived chemotaxin 2). WB:WBGene00019408 K05F1.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC22A15 (solute carrier family 22 member 15). WB:WBGene00019409 K05F1.8 Predicted to be located in membrane. WB:WBGene00019410 K05F1.9 Predicted to be located in cytoskeleton. WB:WBGene00019411 K05F1.10 Predicted to enable serine-type endopeptidase inhibitor activity. Involved in innate immune response. Predicted to be located in extracellular region. WB:WBGene00019412 fbxb-49 Enriched in ABplapppapp; ABprapppapp; and Y cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; tph-1; and csr-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019413 fbxb-50 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and rect_D based on single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Mercuric Chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00019414 fbxb-51 Enriched in several structures, including ABalaapppp; ABalapaapp; ABalappppa; amphid neurons; and rect_D based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including hydrogen sulfide; Alovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019415 K05F6.4 Enriched in ABalaapppa; ABalapaapa; ADE sheath cell; and cholinergic neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on proteomic; microarray; and RNA-seq studies. Is affected by fifteen chemicals including Mercuric Chloride; rotenone; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019416 fbxb-44 Enriched in several structures, including I5 neuron; RME; ciliated neurons; enteric muscle; and head mesodermal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; rotenone; and bisphenol A based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00019417 fbxb-52 Enriched in Caapa and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019418 fbxb-54 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and ciliated neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; rotenone; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019419 K05F6.8 Is affected by several genes including daf-2; mex-1; and ain-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine based on microarray studies. WB:WBGene00019420 fbxb-46 Enriched in MC neuron; MCL; MCR; and pm8 based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019421 K05F6.10 Enriched in GABAergic neurons; coelomocyte; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercury hydroxide; Tunicamycin; and Ethanol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: MATH/TRAF domain. WB:WBGene00019422 K05G3.1 Predicted to enable 3'-5' exonuclease activity. Predicted to be involved in nucleobase-containing compound metabolic process and regulation of macromolecule metabolic process. WB:WBGene00019423 K05G3.2 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and csr-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00019424 aptf-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and sleep. Predicted to be located in nucleus. Expressed in head neurons and pharyngeal neurons. Human ortholog(s) of this gene implicated in Char syndrome; branchiooculofacial syndrome; and dilated cardiomyopathy. Is an ortholog of human TFAP2C (transcription factor AP-2 gamma). WB:WBGene00019425 K06A1.2 Predicted to be located in membrane. WB:WBGene00019426 cutl-16 Predicted to be located in membrane. WB:WBGene00019427 atg-16.2 Involved in defense response to Gram-positive bacterium; gamete generation; and macroautophagy. Located in cytoplasm. Expressed in body wall musculature; embryonic cell; intestine; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Is an ortholog of human ATG16L1 (autophagy related 16 like 1) and ATG16L2 (autophagy related 16 like 2). WB:WBGene00019428 dgk-5 Predicted to enable ATP-dependent diacylglycerol kinase activity. Predicted to be involved in diacylglycerol metabolic process; intracellular signal transduction; and lipid phosphorylation. Is an ortholog of human DGKI (diacylglycerol kinase iota) and DGKZ (diacylglycerol kinase zeta). WB:WBGene00019429 uad-2 Enables H3K27me3 modified histone binding activity. Involved in positive regulation of piRNA transcription. Located in nuclear inner membrane. Part of chromatin. WB:WBGene00019430 K06A5.2 Predicted to be located in membrane. WB:WBGene00019431 K06A5.3 Predicted to be located in cytoskeleton. WB:WBGene00019432 knl-2 Predicted to be involved in cell division; chromosome segregation; and meiotic cell cycle. Located in kinetochore and nucleus. Is an ortholog of human MIS18BP1 (MIS18 binding protein 1). WB:WBGene00019433 acdh-3 Predicted to enable acyl-CoA dehydrogenase activity. Predicted to be located in mitochondrion. Is an ortholog of human ACADSB (acyl-CoA dehydrogenase short/branched chain). WB:WBGene00019434 nmtn-1 Enriched in several structures, including ABalaapppa; ABalapaaaa; ABalapaapa; germ line; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: WD40 repeat; WD domain, G-beta repeat; WD40-repeat-containing domain superfamily; WD repeat-containing protein 47; and WD40/YVTN repeat-like-containing domain superfamily. Is an ortholog of human WDR47 (WD repeat domain 47). WB:WBGene00019435 K06A9.1 Predicted to be located in membrane. WB:WBGene00019436 K06A9.2 Enriched in GABAergic neurons; body wall musculature; head mesodermal cell; and muscle cell based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including tert-Butylhydroperoxide; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: WD40/YVTN repeat-like-containing domain superfamily; F-box-like domain superfamily; and F-box domain. WB:WBGene00019437 K06A9.3 Predicted to be located in membrane. WB:WBGene00019438 cyp-25A6 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. WB:WBGene00019439 K06B9.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00019441 K06B9.4 Enriched in Z1.p; Z4.a; germ line; germline precursor cell; and male distal tip cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by five chemicals including metformin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00019442 K06C4.1 Is affected by several genes including daf-16; sek-1; and pry-1 based on tiling array; RNA-seq; and microarray studies. Is affected by mianserin and multi-walled carbon nanotube based on RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00019444 frpr-11 Predicted to enable G protein-coupled receptor activity. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. WB:WBGene00019445 frpr-12 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in ALML; ALMR; PLML; and PLMR. WB:WBGene00019446 K06C4.14 No description available WB:WBGene00019447 K06C4.15 No description available WB:WBGene00019448 frpr-13 Predicted to be located in membrane. WB:WBGene00019449 K06H6.1 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be located in membrane. Expressed in seam cell. WB:WBGene00019450 K06H6.2 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. Expressed in head neurons and nervous system. WB:WBGene00019451 nstp-7 Predicted to enable UDP-galactose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport and carbohydrate transport. Predicted to be located in Golgi membrane. WB:WBGene00019452 K06H6.4 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00019453 K06H6.5 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00019454 K06H6.6 Is affected by several genes including eat-2; clk-1; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by Chlorpyrifos based on microarray studies. WB:WBGene00019455 K06H7.1 Enriched in I6 neuron; head ganglion; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019456 K06H7.2 Enriched in several structures, including AVA; MSaapaapa; excretory cell; mechanosensory neurons; and muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including levamisole; stavudine; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; F-box protein she-1-like; and F-box domain. WB:WBGene00019457 vms-1 Predicted to enable endonuclease activity and metal ion binding activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Located in cytoplasm and dendrite. Expressed in amphid neurons; head neurons; intestine; tail neurons; and ventral nerve cord. Is an ortholog of human ANKZF1 (ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1). WB:WBGene00019458 K06H7.7 Enriched in germ line; head mesodermal cell; marginal cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Zidovudine; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019459 K06H7.8 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00019460 idi-1 Predicted to enable isopentenyl-diphosphate delta-isomerase activity. Predicted to be involved in isopentenyl diphosphate biosynthetic process. Predicted to be located in cytoplasm. Is an ortholog of human IDI2 (isopentenyl-diphosphate delta isomerase 2). WB:WBGene00019461 K07A3.3 Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in erythropoietic protoporphyria. Is an ortholog of human CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit X). WB:WBGene00019462 ccm-2 Enriched in several structures, including ABarppaapp; ABarpppapp; ABplpppaaa; AVK; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including tryptophan; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: PH-like domain superfamily. WB:WBGene00019464 K07B1.4 Predicted to enable diacylglycerol O-acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human MOGAT1 (monoacylglycerol O-acyltransferase 1) and MOGAT2 (monoacylglycerol O-acyltransferase 2). WB:WBGene00019465 acl-14 Predicted to enable acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Predicted to be located in endoplasmic reticulum. Expressed in head and tail. Is an ortholog of human LPGAT1 (lysophosphatidylglycerol acyltransferase 1). WB:WBGene00019466 tos-1 Enriched in several structures, including ABarpapaapp; ABplaaaaapp; germ line; intestine; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rde-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including aldicarb; rotenone; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00019467 K07B1.7 Predicted to enable nucleic acid binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Is an ortholog of human GPATCH3 (G-patch domain containing 3). WB:WBGene00019469 srz-89 Is affected by four chemicals including Ketamine; resveratrol; and Diazinon based on RNA-seq and microarray studies. WB:WBGene00019470 cyp-35B3 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and human immunodeficiency virus infectious disease. Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2D6 (cytochrome P450 family 2 subfamily D member 6); and CYP2F1 (cytochrome P450 family 2 subfamily F member 1). WB:WBGene00019471 cyp-35B2 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. WB:WBGene00019472 cyp-35B1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in hypodermal cell. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). WB:WBGene00019473 cyp-35A5 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. WB:WBGene00019476 timp-1 Predicted to enable metalloendopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of membrane protein ectodomain proteolysis and response to organic substance. Predicted to be located in extracellular matrix and extracellular space. Expressed in several structures, including coelomocyte; gonad; head neurons; nerve ring; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Duchenne muscular dystrophy; Huntington's disease; artery disease (multiple); and carcinoma (multiple). Is an ortholog of human TIMP2 (TIMP metallopeptidase inhibitor 2). WB:WBGene00019477 cest-17 Predicted to enable carboxylic ester hydrolase activity. Expressed in gonad; intestine; pharynx; and somatic gonad. WB:WBGene00019478 cri-2 Predicted to enable metalloendopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of membrane protein ectodomain proteolysis and response to organic substance. Predicted to be located in extracellular matrix and extracellular space. Expressed in several structures, including enteric muscle; gonad; hyp12; nerve ring; and tail hypodermis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Duchenne muscular dystrophy; artery disease (multiple); reproductive organ cancer (multiple); and urinary system cancer (multiple). Is an ortholog of human TIMP2 (TIMP metallopeptidase inhibitor 2). WB:WBGene00019479 K07C11.7 Predicted to enable hydrolase activity. Is an ortholog of human MPPED1 (metallophosphoesterase domain containing 1) and MPPED2 (metallophosphoesterase domain containing 2). WB:WBGene00019480 K07C11.8 Enriched in several structures, including distal tip cell; head mesodermal cell; intestine; neurons; and pharyngeal-intestinal valve based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019481 cogc-6 Involved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIl. Is an ortholog of human COG6 (component of oligomeric golgi complex 6). WB:WBGene00019482 K07C11.10 Predicted to be involved in receptor localization to non-motile cilium. Predicted to be part of BBSome. Expressed in amphid neurons and phasmid neurons. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 18. Is an ortholog of human BBIP1 (BBSome interacting protein 1). WB:WBGene00019483 K07D4.2 Predicted to enable endonuclease activity. WB:WBGene00019484 K07D4.4 Enriched in ABarpapaapp; ABplaaaaapp; arcade cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and unc-30 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Lithium Chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00019485 K07D4.5 Predicted to be involved in rejection of self pollen. WB:WBGene00019486 K07D4.6 Enriched in excretory duct; excretory pore; head mesodermal cell; and pharynx based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including tryptophan; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00019487 ephx-1 Predicted to enable guanyl-nucleotide exchange factor activity. Expressed in anchor cell; anterior distal tip cell; head; posterior distal tip cell; and uterine toroidal epithelial cell. Is an ortholog of human ARHGEF16 (Rho guanine nucleotide exchange factor 16) and ARHGEF26 (Rho guanine nucleotide exchange factor 26). WB:WBGene00019488 K07D4.9 Enriched in several structures, including arc ant V; head mesodermal cell; hypodermis; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including rotenone; D-glucose; and Psoralens based on RNA-seq studies. WB:WBGene00019489 K07E1.1 Predicted to enable acireductone dioxygenase [iron(II)-requiring] activity. Predicted to be involved in methionine metabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human ADI1 (acireductone dioxygenase 1). WB:WBGene00019490 K07E3.1 Enriched in AFD; OLL; PVD; sensory neurons; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on RNA-seq; tiling array; and microarray studies. Is affected by nine chemicals including Heme; hydrogen sulfide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019491 K07E3.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00019492 K07E3.4 Predicted to enable ATP binding activity and formate-tetrahydrofolate ligase activity. Predicted to be involved in tetrahydrofolate interconversion. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; cleft lip; and developmental cardiac valvular defect. Is an ortholog of human MTHFD1 (methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1). WB:WBGene00019493 catp-5 Enables polyamine transmembrane transporter activity. Involved in polyamine transmembrane transport. Located in apical plasma membrane. Expressed in amphid neurons; excretory cell; germ cell; gonad; and intestine. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Is an ortholog of human ATP13A3 (ATPase 13A3). WB:WBGene00019494 K07E8.1 Enriched in NSM; dopaminergic neurons; and in male based on tiling array and RNA-seq studies. Is affected by several genes including sir-2.1; mut-2; and drh-3 based on tiling array; microarray; and RNA-seq studies. Is affected by resveratrol; Sirolimus; and allantoin based on microarray studies. WB:WBGene00019495 sdz-24 Predicted to enable nucleic acid binding activity. WB:WBGene00019496 frpr-14 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00019497 K07E8.6 Predicted to enable heat shock protein binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in protein folding and protein stabilization. Predicted to be located in cytoplasm. Is an ortholog of human CDC37 (cell division cycle 37, HSP90 cochaperone) and CDC37L1 (cell division cycle 37 like 1, HSP90 cochaperone). WB:WBGene00019498 K07E8.7 Predicted to enable pseudouridine synthase activity. Predicted to be involved in enzyme-directed rRNA pseudouridine synthesis. Is an ortholog of human RPUSD2 (RNA pseudouridine synthase domain containing 2). WB:WBGene00019499 K07E8.10 No description available WB:WBGene00019501 K07E12.2 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00019502 K07G6.1 Enriched in coelomocyte; intestine; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by Atrazine and Sirolimus based on microarray studies. WB:WBGene00019503 tbce-1 Predicted to enable alpha-tubulin binding activity. Predicted to be involved in microtubule cytoskeleton organization; post-chaperonin tubulin folding pathway; and tubulin complex assembly. Located in cytoplasm. Human ortholog(s) of this gene implicated in Kenny-Caffey syndrome type 1; hypoparathyroidism; and hypoparathyroidism-retardation-dysmorphism syndrome. Is an ortholog of human TBCE (tubulin folding cofactor E). WB:WBGene00019504 K07H8.2 Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human SLC41A1 (solute carrier family 41 member 1) and SLC41A2 (solute carrier family 41 member 2). WB:WBGene00019506 K07H8.5 Predicted to be located in membrane. WB:WBGene00019507 K07H8.7 Predicted to be located in membrane. WB:WBGene00019508 K07H8.8 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00019509 K07H8.9 Predicted to enable mRNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. WB:WBGene00019510 nucl-1 Predicted to enable RNA binding activity. Predicted to be located in nucleolus. WB:WBGene00019511 lido-8 Predicted to be located in nucleus. WB:WBGene00019512 K08A2.2 Enriched in germ line; neurons; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including dpy-10; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by nineteen chemicals including tryptophan; methylmercuric chloride; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF1248 and Protein of unknown function (DUF1248). WB:WBGene00019513 lido-7 Predicted to be located in nucleus. WB:WBGene00019514 cpg-20 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; anterior hypodermis; and interfacial epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and mianserin based on RNA-seq and microarray studies. WB:WBGene00019515 ugt-19 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00019516 ugt-20 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00019517 K08B4.5 Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00019518 K08B5.1 Predicted to be located in membrane. WB:WBGene00019519 K08B5.2 Enriched in several structures, including intestine; muscle cell; somatic gonad precursor; tail neurons; and terminal bulb based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00019520 K08B12.1 Predicted to be involved in lipid metabolic process. Expressed in hypodermis. WB:WBGene00019521 dmd-7 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to be located in nucleus. Expressed in several structures, including excretory cell; intestine; pharynx; rectum; and vulval muscle. Is an ortholog of human DMRTC1 (DMRT like family C1) and DMRTC1B (DMRT like family C1B). WB:WBGene00019522 K08B12.3 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Is an ortholog of human HDHD2 (haloacid dehalogenase like hydrolase domain containing 2). WB:WBGene00019524 K08D9.2 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00019525 K08D9.4 Predicted to enable hydrolase activity. WB:WBGene00019526 K08D9.5 Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by Sirolimus and allantoin based on microarray studies. WB:WBGene00019527 K08D9.6 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00019528 K08D10.1 No description available WB:WBGene00019529 K08D10.5 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; allantoin; and metformin based on RNA-seq studies. WB:WBGene00019530 scrm-8 Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be located in plasma membrane. WB:WBGene00019531 scrm-5 Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be located in plasma membrane. WB:WBGene00019532 K08D10.9 Enriched in intestine based on microarray studies. Is affected by several genes including daf-16; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019533 K08D10.10 Enriched in DA neuron; VA neuron; and intestine based on tiling array and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including aldicarb; rotenone; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00019534 K08D10.11 Predicted to be located in membrane. WB:WBGene00019535 tsen-34 Predicted to enable tRNA-intron endonuclease activity. Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2C. Is an ortholog of human TSEN34 (tRNA splicing endonuclease subunit 34). WB:WBGene00019536 rpi-2 Predicted to enable GTPase activator activity. Involved in protein localization to non-motile cilium. Located in cilium and periciliary membrane compartment. Human ortholog(s) of this gene implicated in retinitis pigmentosa 2. Is an ortholog of human RP2 (RP2 activator of ARL3 GTPase). WB:WBGene00019537 K08D12.3 Predicted to enable mRNA binding activity; single-stranded RNA binding activity; and translation regulator activity. Predicted to be involved in positive regulation of cytoplasmic translation. Predicted to be located in cytoplasm. Expressed in head muscle and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in myotonic dystrophy type 2. Is an ortholog of human ZCCHC13 (zinc finger CCHC-type containing 13). WB:WBGene00019538 K08D12.4 Enriched in ADE sheath cell; anterior ganglion; arc ant V; and ciliated neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019540 epic-2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00019541 K08F11.1 Enriched in several structures, including ABalappaap; ABaraappaa; I5 neuron; cholinergic neurons; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including age-1; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including hydrogen sulfide; Alovudine; and metformin based on microarray and RNA-seq studies. WB:WBGene00019542 K08F11.2 No description available WB:WBGene00019543 cif-1 Predicted to enable translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Is an ortholog of human EIF3M (eukaryotic translation initiation factor 3 subunit M). WB:WBGene00019544 miro-1 Predicted to enable GTP binding activity and GTPase activity. Involved in mitochondrion organization. Predicted to be located in mitochondrial outer membrane. Expressed in body wall muscle cell; neurons; and pharyngeal muscle cell. Is an ortholog of human RHOT1 (ras homolog family member T1) and RHOT2 (ras homolog family member T2). WB:WBGene00019545 K09B3.1 Enriched in ABplpppapa; ABprpppapa; AFD; head mesodermal cell; and interfacial epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by Zidovudine; glycine; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00019546 glct-6 Predicted to enable galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity. Predicted to be involved in carbohydrate metabolic process and chondroitin sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in Barrett's esophagus and schizophrenia. Is an ortholog of human B3GAT1 (beta-1,3-glucuronyltransferase 1) and B3GAT2 (beta-1,3-glucuronyltransferase 2). WB:WBGene00019547 K09C4.1 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00019548 K09C4.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00019549 K09C4.4 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00019550 K09C4.5 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00019552 K09C4.7 Enriched in several structures, including Z1.p; Z4.a; coelomocyte; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including let-60; eat-2; and elt-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including aldicarb; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00019553 K09C4.9 Enriched in Z1; Z4; coelomocyte; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eri-1; hpl-2; and mut-2 based on tiling array and microarray studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019554 K09C4.10 Enriched in ABaraappaa; coelomocyte; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by six chemicals including D-glucose; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019556 K09C6.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including endocytosis; positive regulation of canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. WB:WBGene00019557 K09C6.3 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00019558 srbc-12 Predicted to be located in membrane. WB:WBGene00019559 srbc-13 Predicted to be located in membrane. WB:WBGene00019560 K09C6.6 Is affected by drh-3 and klf-1 based on RNA-seq studies. Is affected by Cry5B and Sirolimus based on microarray studies. WB:WBGene00019561 K09C6.7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including endocytosis; positive regulation of canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. WB:WBGene00019562 K09C6.8 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including endocytosis; positive regulation of canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. WB:WBGene00019563 K09C6.9 Enriched in amphid sheath cell and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including nicotinic acid; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00019564 K09D9.1 Involved in innate immune response. WB:WBGene00019565 cyp-35A3 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2D6 (cytochrome P450 family 2 subfamily D member 6); and CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)). WB:WBGene00019566 K09D9.3 Predicted to be located in membrane. WB:WBGene00019567 K09D9.9 Is affected by several genes including daf-16; daf-12; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; multi-walled carbon nanotube; and sucrose based on microarray and RNA-seq studies. WB:WBGene00019568 K09D9.11 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00019569 K09D9.12 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00019570 K09E2.1 Enriched in FLP; hypodermis; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and sek-1 based on RNA-seq and microarray studies. Is affected by four chemicals including sucrose; stearic acid; and single-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: von Willebrand factor A-like domain superfamily; von Willebrand factor, type A; and von Willebrand factor type A domain. WB:WBGene00019571 K09E2.2 Predicted to enable beta-tubulin binding activity and microtubule binding activity. Predicted to be located in axoneme. Is an ortholog of human DNAI7 (dynein axonemal intermediate chain 7). WB:WBGene00019572 K09E2.3 Enriched in several structures, including MSpppaaa; head mesodermal cell; intestine; muscle cell; and sensory neurons based on RNA-seq; proteomic; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; microarray; and RNA-seq studies. Is affected by twelve chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019573 K09E3.1 No description available WB:WBGene00019574 K09E3.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including sir-2.1; sma-2; and sma-4 based on microarray; tiling array; and RNA-seq studies. Is affected by Atrazine and allantoin based on microarray studies. WB:WBGene00019575 K09E3.4 Is affected by several genes including clk-1; pgl-1; and csr-1 based on microarray and RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00019576 lido-5 Predicted to be located in nucleus. WB:WBGene00019577 lido-6 Predicted to be located in nucleus. WB:WBGene00019578 K09E3.7 Enriched in F cell; RICL; RICR; U cell; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; RNA-seq; and tiling array studies. Is affected by nineteen chemicals including Lithium Chloride; D-glucose; and Alovudine based on microarray; RNA-seq; and proteomic studies. WB:WBGene00019579 oac-57 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00019580 oac-58 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00019581 K09E10.3 No description available WB:WBGene00019582 K09F5.1 Enriched in AFD and neurons based on RNA-seq studies. Is affected by eat-2 and etr-1 based on RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019583 K09F5.4 Predicted to be located in membrane. WB:WBGene00019584 set-12 Predicted to enable histone H3K36 methyltransferase activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed in germ line and hypodermis. WB:WBGene00019585 K09F6.2 No description available WB:WBGene00019586 K09F6.3 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00019587 K09F6.4 Enriched in intestine and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00019588 K09F6.5 Enriched in anal sphincter muscle based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including hydrogen sulfide; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00019589 K09F6.6 Enriched in ASER; DVC; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00019590 K09F6.7 Predicted to enable metal ion binding activity. Is an ortholog of human TRIM13 (tripartite motif containing 13) and TRIM59 (tripartite motif containing 59). WB:WBGene00019591 fbxc-25 Enriched in several structures, including ABalpapaap; ABalpapppa; ABalppappa; amphid neurons; and pharyngeal cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019592 K09F6.9 Enriched in coelomocyte; intestine; neurons; and pharynx based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; D-glucose; and 4-bromodiphenyl ether based on microarray and RNA-seq studies. WB:WBGene00019593 K09F6.10 Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in DNA biosynthetic process. WB:WBGene00019594 K09H9.1 Enriched in AFD and germ line based on RNA-seq studies. Is affected by several genes including daf-2; pie-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019595 dscc-1 Predicted to be involved in maintenance of mitotic sister chromatid cohesion. Predicted to be located in chromosome, centromeric region. Predicted to be part of Ctf18 RFC-like complex and chromatin. Is an ortholog of human DSCC1 (DNA replication and sister chromatid cohesion 1). WB:WBGene00019596 K09H9.4 No description available WB:WBGene00019597 K09H9.5 Enriched in OLL; PVD; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including nicotinic acid; rotenone; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00019598 K09H9.7 Expressed in intestine. WB:WBGene00019599 acds-10 Predicted to enable acyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to be located in cytoplasm. Expressed in P3.p hermaphrodite; P4.p hermaphrodite; and P8.p hermaphrodite. Is an ortholog of human ACAD10 (acyl-CoA dehydrogenase family member 10). WB:WBGene00019600 rga-3 Enables GTPase activator activity. Involved in asymmetric protein localization involved in cell fate determination; cortical actin cytoskeleton organization; and regulation of actin filament-based process. Located in cell cortex and centrosome. Expressed in embryonic cell; germ line; and pharyngeal muscle cell. Is an ortholog of human ARHGAP11A (Rho GTPase activating protein 11A). WB:WBGene00019601 K09H11.4 Enriched in anterior hypodermis and interfacial epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including hydrogen sulfide; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00019603 K09H11.6 Predicted to be located in membrane. WB:WBGene00019604 pgph-1 Predicted to enable phosphatase activity. Predicted to be located in cytoplasm. Is an ortholog of human PDXP (pyridoxal phosphatase) and PGP (phosphoglycolate phosphatase). WB:WBGene00019605 ctsa-4.1 Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Human ortholog(s) of this gene implicated in galactosialidosis. Is an ortholog of human CTSA (cathepsin A). WB:WBGene00019606 clec-88 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human KLRF2 (killer cell lectin like receptor F2). WB:WBGene00019607 K10B2.4 Predicted to enable protein folding chaperone. Predicted to be involved in protein folding and protein insertion into ER membrane. Predicted to be located in endoplasmic reticulum membrane. Expressed in excretory cell; head neurons; tail neurons; and ventral nerve cord. Is an ortholog of human WDR83OS (WD repeat domain 83 opposite strand). WB:WBGene00019608 ani-2 Involved in several processes, including female gamete generation; gonad development; and syncytium formation. Located in cytoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 8. Is an ortholog of human ANLN (anillin, actin binding protein). WB:WBGene00019609 K10B3.1 Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including head; hypodermal cell; and tail. Is an ortholog of human ZNF706 (zinc finger protein 706). WB:WBGene00019610 K10B3.2 No description available WB:WBGene00019611 K10B3.5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00019612 gpcp-1 Predicted to enable glycerophosphocholine phosphodiesterase activity. Predicted to be involved in glycerophospholipid catabolic process. Is an ortholog of human GPCPD1 (glycerophosphocholine phosphodiesterase 1). WB:WBGene00019613 K10B4.1 Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. WB:WBGene00019614 srt-54 Predicted to be located in membrane. WB:WBGene00019615 K10B4.3 Predicted to enable phosphatidylinositol-5-phosphate binding activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in plasma membrane. Is an ortholog of human VEPH1 (ventricular zone expressed PH domain containing 1). WB:WBGene00019616 nmur-2 Enables neuropeptide receptor activity. Involved in neuropeptide signaling pathway. Predicted to be located in plasma membrane. Is an ortholog of human NMUR1 (neuromedin U receptor 1) and NMUR2 (neuromedin U receptor 2). WB:WBGene00019617 ctsa-2 Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. WB:WBGene00019618 K10C2.2 Predicted to be located in membrane. WB:WBGene00019619 asp-14 Predicted to enable aspartic-type endopeptidase activity. Involved in innate immune response. Predicted to be located in lysosome. WB:WBGene00019620 fah-1 Predicted to enable fumarylacetoacetase activity. Predicted to be involved in L-phenylalanine catabolic process; homogentisate catabolic process; and tyrosine catabolic process. Expressed in hypodermis. Used to study tyrosinemia type I. Human ortholog(s) of this gene implicated in tyrosinemia type I. Is an ortholog of human FAH (fumarylacetoacetate hydrolase). WB:WBGene00019621 K10C2.6 Enriched in AFD and NSM based on tiling array and RNA-seq studies. Is affected by cyc-1; clk-1; and dpy-21 based on microarray and RNA-seq studies. Is affected by tryptophan based on microarray studies. WB:WBGene00019622 K10C2.7 Enriched in NSM and germ line based on RNA-seq and tiling array studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; Tunicamycin; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00019623 K10C9.1 Enriched in cephalic sheath cell; muscle cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including D-glucose; indole; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019624 rnst-2 Predicted to enable RNA endonuclease activity. Predicted to be involved in RNA catabolic process. Predicted to be located in extracellular region. Expressed in several structures, including intestine; neuronal sheath cell; pharynx; tail; and vulva. Human ortholog(s) of this gene implicated in several diseases, including RNASET2-deficient cystic leukoencephalopathy; adenocarcinoma (multiple); and mismatch repair cancer syndrome. Is an ortholog of human RNASET2 (ribonuclease T2). WB:WBGene00019625 K10C9.4 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00019626 K10C9.7 Enriched in I5 neuron; cholinergic neurons; retrovesicular ganglion; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by fourteen chemicals including methylmercuric chloride; rotenone; and allantoin based on microarray and RNA-seq studies. WB:WBGene00019627 hira-1 Predicted to contribute to nucleosome binding activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus. Predicted to be part of HIR complex. Expressed widely. Used to study chromosome 22q11.2 deletion syndrome, distal. Is an ortholog of human HIRA (histone cell cycle regulator). WB:WBGene00019628 pup-2 Enables RNA uridylyltransferase activity. Involved in pre-miRNA processing. Human ortholog(s) of this gene implicated in breast cancer and liver benign neoplasm. Is an ortholog of human TUT4 (terminal uridylyl transferase 4) and TUT7 (terminal uridylyl transferase 7). WB:WBGene00019629 cid-1 Enables RNA uridylyltransferase activity. Involved in RNA 3' uridylation. Located in P granule; condensed nuclear chromosome; and perinuclear region of cytoplasm. Expressed in germ line and intestine. Human ortholog(s) of this gene implicated in breast cancer and liver benign neoplasm. Is an ortholog of human TUT4 (terminal uridylyl transferase 4) and TUT7 (terminal uridylyl transferase 7). WB:WBGene00019630 emb-1 Predicted to be involved in cell division; meiotic cell cycle; and protein ubiquitination. WB:WBGene00019631 K10D2.5 Enriched in several structures, including ABalpapppa; ABalpppppp; ABarapappa; ABpraaappp; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq; proteomic; and microarray studies. Is affected by five chemicals including manganese chloride; Rifampin; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Cytochrome b5-like heme/steroid binding domain superfamily. WB:WBGene00019633 moc-6 Predicted to enable molybdopterin synthase activity and nucleotide binding activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Predicted to be located in cytosol. Predicted to be part of molybdopterin synthase complex. WB:WBGene00019635 K10E9.2 No description available WB:WBGene00019636 gsto-3 Predicted to enable glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Is an ortholog of human GSTO1 (glutathione S-transferase omega 1) and GSTO2 (glutathione S-transferase omega 2). WB:WBGene00019637 K10F12.5 No description available WB:WBGene00019638 K10F12.6 Is affected by several genes including csr-1; mex-3; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00019639 K10F12.7 Is affected by several genes including elt-2; daf-18; and mex-3 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00019640 dos-2 Enriched in germline precursor cell; interneuron; and tail hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercury hydroxide; D-glucose; and glycine based on RNA-seq and microarray studies. WB:WBGene00019641 cank-26 Predicted to be located in motile cilium. Expressed in PHB; lateral ganglion; and ventral nerve cord. WB:WBGene00019642 K11C4.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00019643 K11C4.2 Predicted to enable signaling receptor activity. Predicted to be located in membrane. Expressed in head. Is an ortholog of human PAQR8 (progestin and adipoQ receptor family member 8). WB:WBGene00019644 cpt-4 Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in carnitine metabolic process and fatty acid metabolic process. Predicted to be located in mitochondrion. WB:WBGene00019645 swt-7 Predicted to enable sugar transmembrane transporter activity. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be located in Golgi membrane. WB:WBGene00019646 K11D12.6 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00019647 K11D12.7 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00019648 K11D12.8 Predicted to be located in membrane. WB:WBGene00019649 exc-14 Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Is an ortholog of human MUL1 (mitochondrial E3 ubiquitin protein ligase 1). WB:WBGene00019650 K11D12.11 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00019651 K11D12.12 Enriched in several structures, including ABalpapaap; ABaraapapp; ABaraapppp; carbon dioxide sensory neurons; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type; Zinc finger, C2H2 type; and Zinc finger C2H2 superfamily. WB:WBGene00019652 cest-34 Predicted to enable carboxylic ester hydrolase activity. WB:WBGene00019653 cest-31 Predicted to enable carboxylic ester hydrolase activity. WB:WBGene00019654 cest-28 Predicted to enable carboxylic ester hydrolase activity. WB:WBGene00019655 K11G9.5 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00019656 slc-25A10 Predicted to enable transmembrane transporter activity. Predicted to be involved in C4-dicarboxylate transport and inorganic anion transport. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 19. Is an ortholog of human SLC25A10 (solute carrier family 25 member 10). WB:WBGene00019657 K11G12.6 Predicted to be involved in protein maturation. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human LMF2 (lipase maturation factor 2). WB:WBGene00019658 K11H12.1 Predicted to be located in mitochondrion. Is an ortholog of human BOLA1 (bolA family member 1). WB:WBGene00019659 K11H12.3 Enriched in intestine and muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Tunicamycin; D-glucopyranose; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00019660 K11H12.4 Enriched in head mesodermal cell; intestine; neurons; and pharyngeal muscle cell based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by thirty-one chemicals including Heme; diallyl trisulfide; and hydrogen sulfide based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00019661 K11H12.5 Enriched in hypodermis; intestine; pharynx; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; bisphenol S; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00019662 K11H12.6 Enriched in ABplpppppp; ABprpppppp; and GABAergic neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and tph-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including 1-methylnicotinamide; multi-walled carbon nanotube; and stavudine based on RNA-seq and microarray studies. WB:WBGene00019663 K11H12.7 Expressed in body wall musculature; head neurons; pharyngeal neurons; and pharynx. WB:WBGene00019664 K11H12.8 Predicted to be located in membrane. Is an ortholog of human GHITM (growth hormone inducible transmembrane protein). WB:WBGene00019665 K11H12.9 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm and nucleus. WB:WBGene00019666 sago-1 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. WB:WBGene00019667 spe-49 Predicted to be located in membrane. Expressed in sperm. Is an ortholog of human DCST1 (DC-STAMP domain containing 1). WB:WBGene00019668 fil-2 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. Expressed in intestine. WB:WBGene00019669 K12B6.4 Predicted to be located in membrane. WB:WBGene00019672 K12B6.8 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including D-glucose; bisphenol A; and stavudine based on RNA-seq and microarray studies. WB:WBGene00019673 K12C11.1 Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Human ortholog(s) of this gene implicated in prolidase deficiency. Is an ortholog of human PEPD (peptidase D). WB:WBGene00019674 K12C11.3 Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in copper ion transmembrane transport and intracellular copper ion homeostasis. Predicted to be located in late endosome membrane. WB:WBGene00019675 K12D9.1 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00019676 irld-46 Enriched in NSM based on tiling array studies. Is affected by several genes including eat-2; clk-1; and his-3 based on microarray and RNA-seq studies. WB:WBGene00019677 K12H4.2 Predicted to enable ribosomal large subunit binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in mitochondrion. Is an ortholog of human MALSU1 (mitochondrial assembly of ribosomal large subunit 1). WB:WBGene00019678 K12H4.3 Predicted to enable RNA binding activity. Predicted to be involved in ribosomal large subunit assembly. Predicted to be located in nucleolus. Is an ortholog of human BRIX1 (biogenesis of ribosomes BRX1). WB:WBGene00019679 spcs-3 Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of signal peptidase complex. Is an ortholog of human SPCS3 (signal peptidase complex subunit 3). WB:WBGene00019680 K12H4.5 Enriched in AFD; ASER; and PLM based on RNA-seq and microarray studies. Is affected by several genes including daf-16; hsf-1; and let-7 based on microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019681 K12H4.6 Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and csr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00019682 K12H4.7 Predicted to enable dipeptidyl-peptidase activity. Involved in innate immune response. Expressed in intestine. Is an ortholog of human PRSS16 (serine protease 16). WB:WBGene00019683 K12H6.2 Predicted to be located in membrane. WB:WBGene00019684 K12H6.4 Enriched in head neurons and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019685 K12H6.5 Enriched in muscle cell; neurons; retrovesicular ganglion; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-12; rrf-3; and csr-1 based on tiling array and RNA-seq studies. Is affected by ten chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019686 K12H6.6 Predicted to be involved in membrane organization and phospholipid homeostasis. Predicted to be located in plasma membrane. Is an ortholog of human TLCD2 (TLC domain containing 2). WB:WBGene00019687 K12H6.7 Enriched in several structures, including ABalaapppa; ABalapaaaa; ABalapaapa; ABalappaap; and cephalic sheath cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00019688 K12H6.8 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including bisphenol A; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00019689 K12H6.9 Enriched in ALN; germ line; head neurons; and in male based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019690 set-13 Enriched in MSpaaapa; germ line; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Alovudine; stavudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SET domain superfamily and SET domain. WB:WBGene00019691 K12H6.12 Expressed in ciliated neurons; head muscle; intestine; and smooth muscle. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00019692 fubl-4 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA processing and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); liver cirrhosis; and malignant astrocytoma. Is an ortholog of human FUBP1 (far upstream element binding protein 1); FUBP3 (far upstream element binding protein 3); and KHSRP (KH-type splicing regulatory protein). WB:WBGene00019693 ostd-1 Involved in endoplasmic reticulum organization and regulation of cell division. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Is an ortholog of human RPN2 (ribophorin II). WB:WBGene00019694 M01A10.4 No description available WB:WBGene00019696 M01B12.1 No description available WB:WBGene00019697 M01B12.4 Enriched in several structures, including ABalpppappp; ABalppppppp; distal tip cell; germ line; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and sir-2.1 based on proteomic; microarray; and RNA-seq studies. Is affected by six chemicals including bisphenol S; Zidovudine; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019698 riok-1 Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including gamete generation; positive regulation of vulval development; and regulation of intracellular signal transduction. Predicted to be located in cytosol. Predicted to be part of preribosome, small subunit precursor. Expressed in gonad; nervous system; and vulva. Is an ortholog of human RIOK1 (RIO kinase 1). WB:WBGene00019699 math-34 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppppaa; ABalpppppa; and amphid neurons based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including tryptophan; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain and MATH domain. WB:WBGene00019700 btb-11 Enriched in XXXL; XXXR; body wall muscle cell; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00019701 M01D1.4 No description available WB:WBGene00019702 fbxb-39 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and ABaraapapaa based on single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and mex-3 based on microarray and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019703 fbxb-41 Enriched in several structures, including ABalpapppa; ABalppappa; cholinergic neurons; ciliated neurons; and pharyngeal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019704 fbxb-40 Enriched in several structures, including ABalpppapa; ABplaapaaa; NSM; amphid neurons; and cephalic sheath cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; bisphenol S; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019705 fbxb-45 Enriched in several structures, including ciliated neurons; germ line; male distal tip cell; pharyngeal neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019706 M01D7.1 Is affected by several genes including daf-2; let-60; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019709 M01E10.3 Is affected by several genes including age-1; pgl-1; and glh-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Atrazine and cadmium based on microarray studies. WB:WBGene00019710 M01E11.1 Predicted to enable protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in endoplasmic reticulum. Is an ortholog of human ICMT (isoprenylcysteine carboxyl methyltransferase). WB:WBGene00019711 ctnb-1 Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Expressed in head muscle; intestine; nerve ring; pharynx; and ventral nerve cord. Human ortholog(s) of this gene implicated in colorectal cancer; morbid obesity; and primary immunodeficiency disease. Is an ortholog of human CTNNBL1 (catenin beta like 1). WB:WBGene00019712 rmh-1 Enables DNA binding activity. Involved in several processes, including DNA recombination; positive regulation of brood size; and positive regulation of reciprocal meiotic recombination. Located in chromosome and nucleoplasm. Is an ortholog of human RMI1 (RecQ mediated genome instability 1). WB:WBGene00019713 pqn-52 Enriched in several structures, including CAN; cholinergic neurons; coelomocyte; germ line; and head mesodermal cell based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; let-7; and gld-1 based on proteomic; RNA-seq; and microarray studies. Is affected by eighteen chemicals including aldicarb; rotenone; and Psoralens based on microarray; RNA-seq; and proteomic studies. WB:WBGene00019714 M01G4.1 Is affected by cyc-1 and camt-1 based on microarray and RNA-seq studies. WB:WBGene00019715 M01G5.1 Enriched in several structures, including ABalpapaap; ABarappaap; AFD; germ line; and head mesodermal cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including glp-1; hsf-1; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including rotenone; bisphenol S; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00019716 tmem-120 Predicted to be located in membrane. Is an ortholog of human TMEM120A (transmembrane protein 120A) and TMEM120B (transmembrane protein 120B). WB:WBGene00019717 trx-3 Predicted to be involved in photoreceptor cell maintenance and sensory perception. Located in apical plasma membrane; cytoplasm; and nucleus. Is an ortholog of human NXNL2 (nucleoredoxin like 2). WB:WBGene00019718 M01H9.2 Enriched in head mesodermal cell and pharyngeal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00019719 M01H9.3 Enriched in several structures, including XXX cell; coelomocyte; germ line; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019720 M01H9.4 Enriched in several structures, including ABarpapaapp; ABarppaapp; ABarpppapp; head mesodermal cell; and neurons based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Tunicamycin; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019721 M01H9.5 Enriched in several structures, including ABalaappppa; ABalapaappa; accessory cell; head mesodermal cell; and lateral ganglion based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Cry5B; cholesterol; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00019722 M02A10.1 Predicted to be located in membrane. WB:WBGene00019723 fbxc-47 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABprpaaapa; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; Sirolimus; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF3557. WB:WBGene00019724 M02B7.2 Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to be involved in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in cytoplasm. Is an ortholog of human ERI3 (ERI1 exoribonuclease family member 3). WB:WBGene00019725 algn-14 Predicted to enable transferase activity. Predicted to contribute to N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane and nuclear membrane. Predicted to be part of UDP-N-acetylglucosamine transferase complex. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 15. Is an ortholog of human ALG14 (ALG14 UDP-N-acetylglucosaminyltransferase subunit). WB:WBGene00019726 bris-1 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Human ortholog(s) of this gene implicated in intellectual developmental disorder with short stature and behavioral abnormalities; lung adenocarcinoma; and non-syndromic X-linked intellectual disability 1. Is an ortholog of human IQSEC1 (IQ motif and Sec7 domain ArfGEF 1); IQSEC2 (IQ motif and Sec7 domain ArfGEF 2); and IQSEC3 (IQ motif and Sec7 domain ArfGEF 3). WB:WBGene00019727 zig-12 Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Expressed in body wall musculature and vulval muscle. WB:WBGene00019728 M02D8.2 Enriched in AVHL; AVHR; anterior spermatheca; coelomocyte; and posterior spermatheca based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including manganese chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019729 M02D8.3 Predicted to enable sodium:proton antiporter activity. Predicted to be involved in proton export across plasma membrane; regulation of membrane potential; and sodium ion export across plasma membrane. Predicted to be located in plasma membrane. WB:WBGene00019730 asns-2 Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity. Predicted to be involved in asparagine biosynthetic process. Predicted to be located in cytosol. Is an ortholog of human ASNS (asparagine synthetase (glutamine-hydrolyzing)). WB:WBGene00019731 M02D8.5 Enriched in FLPL; FLPR; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including Tunicamycin; levamisole; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Spermadhesin, CUB domain superfamily. WB:WBGene00019732 M02D8.6 Enriched in body wall muscle cell; enteric muscle; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including D-glucose; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00019733 M02E1.1 Enriched in coelomocyte; neurons; and retrovesicular ganglion based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including stavudine; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019734 nlp-64 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00019735 M02F4.1 Enriched in intestine and neurons based on RNA-seq and microarray studies. Is affected by several genes including unc-30; prg-1; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019736 M02F4.2 Enriched in intestine based on microarray studies. Is affected by several genes including mex-1; dpy-21; and set-2 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019738 clec-265 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. WB:WBGene00019739 M02F4.9 Is affected by several genes including mut-16; etr-1; and swsn-1 based on tiling array and RNA-seq studies. WB:WBGene00019740 srt-31 Predicted to be located in membrane. WB:WBGene00019741 nhr-201 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00019742 nhr-202 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00019743 nhr-203 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00019744 M02H5.8 Predicted to be located in ribosome. WB:WBGene00019745 srbc-57 Predicted to be located in membrane. WB:WBGene00019746 M03A1.3 Predicted to be located in membrane. WB:WBGene00019747 ipla-1 Enables identical protein binding activity; phospholipase activity; and phospholipid binding activity. Involved in glycerophospholipid metabolic process; regulation of asymmetric cell division; and regulation of protein localization. Located in cytosol; endoplasmic reticulum; and nucleus. Part of phosphatase complex. Expressed in pharyngeal-intestinal valve; rectum; and spermatheca. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 28. Is an ortholog of human DDHD1 (DDHD domain containing 1). WB:WBGene00019748 atg-2 Predicted to enable phosphatidylinositol-3-phosphate binding activity. Involved in positive regulation of autophagy. Predicted to be located in phagophore assembly site. Expressed in AIYL and AIYR. Is an ortholog of human ATG2A (autophagy related 2A). WB:WBGene00019749 M03A8.3 Enriched in several structures, including ASG; enteric muscle; excretory gland cell; head mesodermal cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including aldicarb; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: PH-like domain superfamily. WB:WBGene00019750 M03D4.3 Enriched in neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and isp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including aldicarb; D-glucose; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00019751 M03D4.4 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in pharyngeal muscle cell. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Is an ortholog of human VEZF1 (vascular endothelial zinc finger 1). WB:WBGene00019753 M03E7.1 Predicted to be located in cytoskeleton. WB:WBGene00019754 M03E7.2 Predicted to be located in membrane. WB:WBGene00019755 M03E7.3 Predicted to be located in membrane. WB:WBGene00019756 lrpc-1 Predicted to enable chitin binding activity. Predicted to be located in extracellular region. WB:WBGene00019757 memb-2 Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in vesicle fusion. Predicted to be located in endomembrane system. Predicted to be part of SNARE complex. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 6. Is an ortholog of human GOSR2 (golgi SNAP receptor complex member 2). WB:WBGene00019758 M03F4.4 Enriched in ABplpaapap and ABprpaapap based on single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00019759 M03F4.6 Enriched in several structures, including interfacial epithelial cell; motor neurons; rectal gland cell; sensory neurons; and spermatheca based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including Neurotoxins; sesamin; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Growth factor receptor cysteine-rich domain superfamily; EB domain; EB module; and Cysteine-rich repeat. WB:WBGene00019760 calu-1 Enables calcium ion binding activity. Involved in cuticle development. Located in endoplasmic reticulum. Expressed in tail. Human ortholog(s) of this gene implicated in colorectal carcinoma. Is an ortholog of human CALU (calumenin). WB:WBGene00019761 M03F8.1 Predicted to be located in membrane. WB:WBGene00019762 syf-3 Predicted to be involved in spliceosomal complex assembly. Predicted to be part of Prp19 complex; U2-type catalytic step 2 spliceosome; and post-mRNA release spliceosomal complex. Human ortholog(s) of this gene implicated in basal cell carcinoma. Is an ortholog of human CRNKL1 (crooked neck pre-mRNA splicing factor 1). WB:WBGene00019763 galt-1 Enables beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity. Involved in N-glycan processing and protein galactosylation. Predicted to be located in cytoplasm. Expressed in coelomocyte and intestine. WB:WBGene00019764 M03F8.5 Predicted to be located in membrane. WB:WBGene00019765 M03F8.6 Predicted to enable extracellular ligand-gated monoatomic ion channel activity and metallopeptidase activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00019766 slmp-1 Enriched in ABalappaap; ABprpapppa; AFD; germ line; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; let-7; and gld-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. Human SLMAP enables small GTPase binding activity. Is predicted to encode a protein with the following domains: Forkhead-associated (FHA) domain; SMAD/FHA domain superfamily; and FHA domain. Is an ortholog of human SLMAP (sarcolemma associated protein). WB:WBGene00019767 rpa-2 Enables enzyme binding activity. Predicted to be involved in DNA replication; double-strand break repair via homologous recombination; and nucleotide-excision repair. Predicted to be located in chromosome, telomeric region and site of double-strand break. Predicted to be part of DNA replication factor A complex. Expressed in pharyngeal neurons and seam cell. Is an ortholog of human RPA2 (replication protein A2). WB:WBGene00019768 M04F3.2 Enriched in AFD; germ line; intestine; mechanosensory neurons; and rectal epithelium based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by four chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq studies. WB:WBGene00019769 kin-35 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00019770 M04F3.4 Predicted to enable calcium ion binding activity. Is an ortholog of human PDCD6 (programmed cell death 6). WB:WBGene00019771 M04F3.5 Predicted to enable actin binding activity and phospholipid binding activity. Involved in cell projection assembly and membrane organization. Located in cytoplasmic side of plasma membrane and filopodium. Human ortholog(s) of this gene implicated in intellectual developmental disorder with ocular anomalies and distinctive facial features. Is an ortholog of human MTSS2 (MTSS I-BAR domain containing 2). WB:WBGene00019772 M04G7.1 Expressed in pharyngeal gland cell. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00019773 M04G7.2 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00019774 npr-37 Predicted to be located in membrane. WB:WBGene00019776 M6.4 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and unc-30 based on microarray and RNA-seq studies. WB:WBGene00019777 M57.1 Enriched in hypodermis; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including mianserin; Zidovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00019778 M57.2 Predicted to enable protein prenyltransferase activity. Predicted to contribute to Rab geranylgeranyltransferase activity. Predicted to be located in cytoplasm. Predicted to be part of Rab-protein geranylgeranyltransferase complex. Is an ortholog of human RABGGTA (Rab geranylgeranyltransferase subunit alpha). WB:WBGene00019779 endu-2 Predicted to enable RNA endonuclease activity. Involved in defense response to Gram-negative bacterium and innate immune response. Expressed in several structures, including coelomocyte; germ line; head muscle; muscle cell; and neurons. Used to study cancer. WB:WBGene00019780 M60.4 Predicted to be located in membrane. WB:WBGene00019781 M60.6 Predicted to be located in membrane. Expressed in gonadal sheath cell; pharynx; tail neurons; and vm1. WB:WBGene00019782 M60.7 Predicted to be involved in intracellular signal transduction. Is an ortholog of human ASB14 (ankyrin repeat and SOCS box containing 14) and ASB15 (ankyrin repeat and SOCS box containing 15). WB:WBGene00019783 M70.1 Predicted to be located in membrane. WB:WBGene00019784 M70.2 Is affected by several genes including daf-2; age-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; Doxycycline; and cadmium based on microarray and RNA-seq studies. WB:WBGene00019785 M70.3 Predicted to be located in membrane. WB:WBGene00019786 famp-1 Predicted to be located in extracellular space. Is an ortholog of human FAM3C (FAM3 metabolism regulating signaling molecule C). WB:WBGene00019787 M70.5 Expressed in pharynx. Is predicted to encode a protein with the following domain: Six-bladed beta-propeller, TolB-like. WB:WBGene00019788 M116.1 Enriched in body wall muscle cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019789 M116.2 Enriched in germline precursor cell and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Alovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019790 M116.3 No description available WB:WBGene00019791 sdz-25 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019792 M116.5 Predicted to enable actin binding activity and microtubule binding activity. Predicted to be involved in actin cytoskeleton organization. Predicted to be located in microtubule organizing center. Predicted to be part of filamentous actin. WB:WBGene00019793 M151.1 Is affected by several genes including eat-2; sek-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Alovudine; allantoin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019794 M151.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Zidovudine; glycine; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00019795 M151.3 Enriched in Z1; Z4; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00019796 M151.4 Enriched in Z1; Z4; germ line; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; unc-30; and alg-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00019797 fbxb-31 Enriched in I5 neuron; g2L; g2R; and germ line based on proteomic and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including Mercuric Chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019798 fbxb-32 Is affected by several genes including daf-2; eat-2; and mex-3 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00019799 M151.7 Enriched in NSM; amphid neurons; germ line; germline precursor cell; and rectal epithelium based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00019800 mtss-1 Predicted to enable single-stranded DNA binding activity. Predicted to be involved in mitochondrial DNA replication. Predicted to be located in mitochondrial nucleoid. Expressed in head; intestine; and tail. Human ortholog(s) of this gene implicated in optic atrophy. Is an ortholog of human SSBP1 (single stranded DNA binding protein 1). WB:WBGene00019801 aak-1 Predicted to enable protein serine/threonine kinase activity. Involved in negative regulation of cell population proliferation and pharyngeal pumping. Predicted to be part of nucleotide-activated protein kinase complex. WB:WBGene00019803 PDB1.1 Predicted to enable monoatomic cation transmembrane transporter activity. Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00019804 R01B10.2 Enriched in MSpaapaa based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019805 R01B10.3 Predicted to be located in membrane. WB:WBGene00019806 pgap-3 Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 4. Is an ortholog of human PGAP3 (post-GPI attachment to proteins phospholipase 3). WB:WBGene00019807 jamp-1 Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be located in membrane. Expressed in amphid neurons; intestine; pharyngeal neurons; and sensory neurons. Is an ortholog of human JKAMP (JNK1/MAPK8 associated membrane protein). WB:WBGene00019808 seip-1 Predicted to be involved in lipid droplet organization and lipid storage. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 2 and hereditary spastic paraplegia 17. Is an ortholog of human BSCL2 (BSCL2 lipid droplet biogenesis associated, seipin). WB:WBGene00019809 R01H2.1 Enriched in germ line based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and dpy-21 based on RNA-seq and microarray studies. Is affected by fluoranthene; Chlorpyrifos; and tetrabromobisphenol A based on microarray studies. WB:WBGene00019810 R01H2.2 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Peptidase S1, PA clan; Nematode trypsin-6-like family; and Chymotrypsin family Peptidase-S1. WB:WBGene00019811 egg-2 Predicted to enable signaling receptor activity. Involved in positive regulation of protein localization to cell periphery and sexual reproduction. Located in plasma membrane. Expressed in germ line. WB:WBGene00019812 R01H2.4 Enriched in M cell; germ line; hypodermis; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including aldicarb; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00019813 ger-1 Enables GDP-L-fucose synthase activity. Involved in GDP-L-fucose biosynthetic process. Expressed in pharynx; seam cell; and spermatheca. Is an ortholog of human GFUS (GDP-L-fucose synthase). WB:WBGene00019814 R02C2.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including establishment of cell polarity; positive regulation of vesicle transport along microtubule; and regulation of Wnt signaling pathway. Predicted to be located in cytoplasm and nucleus. WB:WBGene00019815 kin-34 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CHEK1 (checkpoint kinase 1). WB:WBGene00019816 nhr-204 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00019817 txt-2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CHEK1 (checkpoint kinase 1). WB:WBGene00019818 R02C2.7 Enriched in pharyngeal muscle cell based on tiling array and proteomic studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-five chemicals including tryptophan; rotenone; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4440; Domain of unknown function (DUF4440); and NTF2-like domain superfamily. WB:WBGene00019819 aass-1 Predicted to enable saccharopine dehydrogenase activity. Predicted to be involved in lysine biosynthetic process via aminoadipic acid. Predicted to be located in cytoplasm. Expressed in gonadal sheath cell and hypodermal cell. Human ortholog(s) of this gene implicated in hyperlysinemia. Is an ortholog of human AASS (aminoadipate-semialdehyde synthase). WB:WBGene00019820 cogc-8 Involved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIh. Is an ortholog of human COG8 (component of oligomeric golgi complex 8). WB:WBGene00019821 gtf-2H1 Predicted to be involved in DNA repair; transcription by RNA polymerase I; and transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIH core complex and transcription factor TFIIH holo complex. Expressed widely. Is an ortholog of human GTF2H1 (general transcription factor IIH subunit 1). WB:WBGene00019822 ints-13 Predicted to be involved in centrosome localization and regulation of mitotic cell cycle. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be part of integrator complex. Is an ortholog of human INTS13 (integrator complex subunit 13). WB:WBGene00019823 fnta-1 Enables protein farnesyltransferase activity. Predicted to be located in cytoplasm. Predicted to be part of CAAX-protein geranylgeranyltransferase complex and protein farnesyltransferase complex. Is an ortholog of human FNTA (farnesyltransferase, CAAX box, alpha). WB:WBGene00019824 R02D3.7 Expressed in body wall musculature; excretory cell; head muscle; seam cell; and ventral nerve cord. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00019825 R02D3.8 Predicted to enable 3'-5'-RNA exonuclease activity. Involved in PERK-mediated unfolded protein response and innate immune response. Predicted to be located in cytoplasm. Is an ortholog of human ERI3 (ERI1 exoribonuclease family member 3). WB:WBGene00019826 R02E4.1 Expressed in head mesodermal cell; hermaphrodite distal tip cell; non-striated muscle; and rectal epithelium. WB:WBGene00019827 mop-25.1 Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in intracellular signal transduction. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and pancreatic cancer. Is an ortholog of human CAB39 (calcium binding protein 39) and CAB39L (calcium binding protein 39 like). WB:WBGene00019828 R02E12.4 Predicted to be involved in cilium assembly and cilium movement involved in cell motility. Predicted to be located in microtubule cytoskeleton. Human ortholog(s) of this gene implicated in spermatogenic failure. Is an ortholog of human TEKT3 (tektin 3); TEKT4 (tektin 4); and TEKT5 (tektin 5). WB:WBGene00019829 R02E12.5 Enriched in intestine; neurons; and rectal epithelium based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4612; Domain of unknown function (DUF4612); and Phosphorylation site. Is an ortholog of human C1orf21 (chromosome 1 open reading frame 21). WB:WBGene00019830 hrg-1 Enables heme binding activity and heme transmembrane transporter activity. Involved in heme transport. Located in endosome membrane and lysosomal membrane. Is an ortholog of human SLC48A1 (solute carrier family 48 member 1). WB:WBGene00019831 R02F2.1 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in mitotic cell cycle phase transition. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Human papillomavirus infectious disease; cervix uteri carcinoma in situ; and endocrine gland cancer (multiple). Is an ortholog of human CCNI (cyclin I). WB:WBGene00019832 osg-1 Predicted to enable guanyl-nucleotide exchange factor activity. Involved in response to oxidative stress. Expressed in body wall musculature and head neurons. Is an ortholog of human ARHGEF17 (Rho guanine nucleotide exchange factor 17). WB:WBGene00019833 R02F2.4 Predicted to enable chitin binding activity. Predicted to be located in extracellular region. WB:WBGene00019834 R02F2.5 Enriched in several structures, including ABplppppap; ABprppppap; amphid sheath cell; germ line; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00019835 R02F2.6 Enriched in AFD and germ line based on RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00019836 R02F2.7 Enriched in NSM; body wall muscle cell; germ line; and marginal cell based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including mianserin; paraquat; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00019837 R02F2.8 Predicted to be located in membrane. WB:WBGene00019838 R02F2.9 Predicted to enable aminoacyl-tRNA hydrolase activity and translation release factor activity, codon nonspecific. Predicted to be involved in mitochondrial translational termination. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL58 (mitochondrial ribosomal protein L58). WB:WBGene00019839 R02F11.1 Enriched in arcade cell; pharyngeal-intestinal valve; pharynx; sensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-six chemicals including methylmercury hydroxide; 1-methylnicotinamide; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00019840 R02F11.2 Predicted to be located in membrane. WB:WBGene00019841 R02F11.3 Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in membrane. WB:WBGene00019842 ccep-97 Predicted to enable alpha-tubulin binding activity and dynein heavy chain binding activity. Predicted to be involved in outer dynein arm assembly. Predicted to be located in cytoplasm. Is an ortholog of human CEP97 (centrosomal protein 97). WB:WBGene00019843 R03E9.2 Predicted to enable Glc3Man9GlcNAc2 oligosaccharide glucosidase activity. Predicted to be involved in oligosaccharide metabolic process. Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00019844 abts-4 Predicted to enable transmembrane transporter activity. Predicted to be involved in bicarbonate transport; regulation of intracellular pH; and transmembrane transport. Located in basolateral plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including glucosephosphate dehydrogenase deficiency; hereditary elliptocytosis; and renal tubular acidosis. Is an ortholog of human SLC4A2 (solute carrier family 4 member 2) and SLC4A3 (solute carrier family 4 member 3). WB:WBGene00019845 irld-13 Enriched in interfacial epithelial cell and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-12; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00019846 gpx-7 Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Located in cytosol. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple) and spondylometaphyseal dysplasia Sedaghatian type. Is an ortholog of human GPX4 (glutathione peroxidase 4). WB:WBGene00019847 R03G5.6 Predicted to be located in membrane. WB:WBGene00019849 oac-40 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00019850 srt-18 Predicted to be located in membrane. WB:WBGene00019851 oac-41 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00019853 srsx-20 Enriched in neurons based on microarray studies. Is affected by several genes including daf-2; sek-1; and nhr-49 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Atrazine based on RNA-seq and microarray studies. WB:WBGene00019854 R03H10.1 Enriched in CANL; CANR; body wall muscle cell; coelomocyte; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including hydrogen sulfide; methylmercuric chloride; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: F-box protein she-1-like. WB:WBGene00019855 R03H10.2 Predicted to be located in membrane. WB:WBGene00019856 R03H10.4 Expressed in seminal vesicle. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00019857 R03H10.5 Enriched in coelomocyte and in male based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and alg-1 based on RNA-seq and microarray studies. Is affected by resveratrol; cadmium; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00019858 R03H10.6 Enables double-stranded DNA binding activity. Predicted to be involved in DNA metabolic process and meiotic cell cycle. Predicted to be part of DNA replication factor A complex. Is an ortholog of human RPA1 (replication protein A1). WB:WBGene00019859 R03H10.7 Predicted to enable damaged DNA binding activity and single-stranded telomeric DNA binding activity. Predicted to be involved in DNA metabolic process and meiotic cell cycle. Predicted to be part of DNA replication factor A complex. Is an ortholog of human RPA1 (replication protein A1). WB:WBGene00019860 R03H10.9 No description available WB:WBGene00019861 R04A9.1 Predicted to be located in membrane. WB:WBGene00019862 nrde-3 Enables siRNA binding activity. Involved in RNA import into nucleus; olfactory learning; and regulation of gene expression. Located in nucleus. Part of RNAi effector complex. Expressed in AWCL and AWCR. WB:WBGene00019863 R04A9.3 Enriched in AVA; hypodermis; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including stavudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00019864 ceh-93 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ADLL; ADLR; and seam cell. WB:WBGene00019865 R04A9.6 Enriched in AVE and hypodermis based on tiling array studies. Is affected by several genes including hsf-1; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; multi-walled carbon nanotube; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00019866 R04B3.1 Enriched in hyp3 and interfacial epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by ten chemicals including Ethanol; methylmercury hydroxide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00019867 R04B3.2 Predicted to enable N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity; asparaginase activity; and beta-aspartyl-peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in aspartylglucosaminuria. Is an ortholog of human AGA (aspartylglucosaminidase). WB:WBGene00019868 R04B3.3 Enriched in amphid sheath cell; excretory system; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; glp-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Ethanol; D-glucose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019869 cnnm-2 Predicted to enable transmembrane transporter activity. Involved in determination of adult lifespan and positive regulation of gonad development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in Jalili syndrome and renal hypomagnesemia 6. Is an ortholog of several human genes including CNNM1 (cyclin and CBS domain divalent metal cation transport mediator 1); CNNM3 (cyclin and CBS domain divalent metal cation transport mediator 3); and CNNM4 (cyclin and CBS domain divalent metal cation transport mediator 4). WB:WBGene00019870 R04E5.7 Enriched in neurons and pharynx based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and pgl-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019871 R04E5.8 Predicted to enable microtubule binding activity. Predicted to be located in cytoplasm. WB:WBGene00019872 R04E5.9 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalaapppa; ABalapaaaa; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019873 arrd-26 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. WB:WBGene00019874 R05C11.2 Enriched in AVA; AVK; GABAergic neurons; neurons; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; sek-1; and tph-1 based on tiling array and RNA-seq studies. Is affected by seven chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00019875 mca-2 Predicted to enable P-type calcium transporter activity. Predicted to be involved in regulation of cytosolic calcium ion concentration. Predicted to be located in intracellular membrane-bounded organelle. Expressed in hypodermis. Human ortholog(s) of this gene implicated in X-linked spinocerebellar ataxia 1; autosomal dominant intellectual developmental disorder; and nonsyndromic deafness (multiple). Is an ortholog of several human genes including ATP2B1 (ATPase plasma membrane Ca2+ transporting 1); ATP2B2 (ATPase plasma membrane Ca2+ transporting 2); and ATP2B3 (ATPase plasma membrane Ca2+ transporting 3). WB:WBGene00019877 lmbr-1 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in bone development disease (multiple) and hypoplastic or aplastic tibia with polydactyly. Is an ortholog of human LMBR1 (limb development membrane protein 1) and LMBR1L (limb development membrane protein 1 like). WB:WBGene00019878 R05D3.3 Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. WB:WBGene00019879 R05D3.5 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Tunicamycin; Cry5B; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. WB:WBGene00019880 R05D3.6 Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Is an ortholog of human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2). WB:WBGene00019881 R05D3.8 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of catalytic step 2 spliceosome. WB:WBGene00019882 R05D3.9 Enriched in several structures, including DB neuron; anterior hypodermis; gonadal sheath cell; interfacial epithelial cell; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Thioredoxin domain-containing protein 16 and Thioredoxin-like superfamily. WB:WBGene00019883 met-2 Enables histone H3K36 methyltransferase activity and histone H3K9 methyltransferase activity. Involved in several processes, including negative regulation of vulval development; regulation of gene expression; and vulval cell fate commitment. Located in cytoplasm. Expressed in hypodermis; intestine; muscle cell; neurons; and in male. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; autistic disorder; and prostate cancer. Is an ortholog of human SETDB1 (SET domain bifurcated histone lysine methyltransferase 1). WB:WBGene00019884 R05D3.12 Predicted to enable DNA binding activity; DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; and ion binding activity. Predicted to be involved in resolution of meiotic recombination intermediates and sister chromatid segregation. Predicted to be located in nucleus. WB:WBGene00019885 R05D8.7 Predicted to enable nucleotide binding activity and oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00019886 R05D8.9 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00019887 R05D8.11 Enriched in germline precursor cell; hypodermis; intestine; and ventral nerve cord based on tiling array and single-cell RNA-seq studies. Is affected by several genes including clk-1; dpy-7; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00019888 btbd-10 Predicted to be involved in positive regulation of phosphorylation. Predicted to be located in cytoplasm. Expressed in hypodermal cell; intestine; pharyngeal neurons; and pharyngeal-intestinal valve. Is an ortholog of human BTBD10 (BTB domain containing 10) and KCTD20 (potassium channel tetramerization domain containing 20). WB:WBGene00019889 R05F9.4 No description available WB:WBGene00019890 R05F9.6 Predicted to enable phosphoglucomutase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in cytosol. Expressed in head. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation It; endometrial cancer; and teratoma. Is an ortholog of human PGM1 (phosphoglucomutase 1) and PGM5 (phosphoglucomutase 5). WB:WBGene00019891 R05F9.7 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00019892 R05F9.9 Enriched in several structures, including body wall muscle cell; germ line; neurons; retrovesicular ganglion; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019893 sgt-1 Predicted to enable molecular adaptor activity. Predicted to be involved in post-translational protein targeting to endoplasmic reticulum membrane. Predicted to be located in membrane. Predicted to be part of TRC complex. Is an ortholog of human SGTA (small glutamine rich tetratricopeptide repeat co-chaperone alpha) and SGTB (small glutamine rich tetratricopeptide repeat co-chaperone beta). WB:WBGene00019894 R05F9.11 Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be part of snRNA-activating protein complex. WB:WBGene00019895 aagr-2 Enables alpha-1,4-glucosidase activity. Involved in glycogen catabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in congenital sucrase-isomaltase deficiency and glycogen storage disease II. Is an ortholog of human MGAM (maltase-glucoamylase). WB:WBGene00019896 R05G6.1 Enriched in head mesodermal cell; neurons; rectal epithelial cell; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00019897 R05G6.2 No description available WB:WBGene00019898 R05G6.4 Predicted to enable ubiquitin protein ligase activity. Predicted to be located in nucleus. Is an ortholog of human NOSIP (nitric oxide synthase interacting protein). WB:WBGene00019899 R05G6.5 Enriched in several structures, including ABalapapapa; ASG; BAG; germ line; and outer labial neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; pgl-1; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Is predicted to encode a protein with the following domains: Dpy-30 motif and Nucleoside diphosphate kinase-like domain superfamily. Is an ortholog of human NME5 (NME/NM23 family member 5). WB:WBGene00019900 vdac-1 Predicted to enable voltage-gated monoatomic anion channel activity. Involved in mitochondrion organization. Acts upstream of or within with a positive effect on olfactory behavior. Located in mitochondrion. Expressed in AWCL and AWCR. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinsonism; and prostate cancer. Is an ortholog of human VDAC1 (voltage dependent anion channel 1) and VDAC2 (voltage dependent anion channel 2). WB:WBGene00019901 R05G6.9 Predicted to enable calcium ion binding activity. Is an ortholog of human DLK2 (delta like non-canonical Notch ligand 2). WB:WBGene00019902 R05G6.10 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in plasma membrane. Expressed in neurons; pharynx; and rectal gland cell. Is an ortholog of human RASGEF1B (RasGEF domain family member 1B). WB:WBGene00019903 R05G9.1 Enriched in AVK; NSM; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; uaf-1; and mrps-5 based on tiling array; RNA-seq; and microarray studies. Is affected by resveratrol and dafa#1 based on microarray studies. WB:WBGene00019904 twk-49 Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. WB:WBGene00019905 R05G9.3 Predicted to be located in membrane. WB:WBGene00019906 R05G9R.1 Enriched in ADE sheath cell; hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019907 R05H11.1 Enriched in coelomocyte; germ line; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including D-glucose; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019908 R05H11.2 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and XXX cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on RNA-seq; tiling array; and microarray studies. Is affected by nine chemicals including manganese chloride; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019909 R06A10.1 Predicted to be located in membrane. WB:WBGene00019911 R06A10.4 Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Is an ortholog of human PSKH2 (protein serine kinase H2). WB:WBGene00019912 R06B10.1 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and lin-4 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; 1-methylnicotinamide; and nicotinic acid based on microarray and RNA-seq studies. WB:WBGene00019913 R06B10.2 Enriched in AFD; germ line; rect_D; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00019914 clec-150 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. WB:WBGene00019915 tbc-10 Predicted to enable GTPase activator activity. Is an ortholog of human TBC1D10A (TBC1 domain family member 10A) and TBC1D10C (TBC1 domain family member 10C). WB:WBGene00019916 R06B10.7 Is affected by several genes including mex-1; ifg-1; and rsr-2 based on tiling array; microarray; and RNA-seq studies. Is affected by Chlorpyrifos and Diazinon based on microarray studies. WB:WBGene00019917 clec-43 Expressed in int1DL; int1DR; int1VL; and int1VR. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; and C-type lectin fold. WB:WBGene00019918 fbxc-36 Enriched in several structures, including amphid neurons; amphid sheath cell; germ line; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Cry5B; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019919 R07C3.3 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00019920 acs-15 Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in acute myeloid leukemia and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1) and ACSL6 (acyl-CoA synthetase long chain family member 6). WB:WBGene00019921 fbxc-34 Enriched in several structures, including ABalpapppa; MSpppaaa; RIM; head mesodermal cell; and pharynx based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019922 fbxc-28 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; BAG; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019923 fbxc-29 Enriched in several structures, including ABalapppaa; ABalpppappp; AVE; amphid neurons; and enteric muscle based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; mianserin; and bisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019924 fbxc-33 Enriched in K cell; K' cell; MSaapaapa; MSpapaapa; and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by eight chemicals including Alovudine; Zidovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019925 fbxc-31 Enriched in ABalappaap; ABalpapaap; ABarappaap; AVL; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Alovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019926 fbxc-27 Enriched in body wall muscle cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Alovudine; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019927 fbxc-24 Enriched in body wall muscle cell and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00019928 clec-44 Is affected by several genes including eat-2; elt-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00019929 R07C3.13 Enriched in Caapa; MSpppaaa; germ line; head mesodermal cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-two chemicals including methylmercuric chloride; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00019930 fbxc-35 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019931 R07C12.1 Enriched in DA neuron; VA neuron; and dopaminergic neurons based on tiling array and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including Tunicamycin; levamisole; and procyanidin based on microarray and RNA-seq studies. WB:WBGene00019932 R07C12.2 Enriched in OLL; PVD; head mesodermal cell; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including Psoralens; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00019933 R07C12.3 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Alovudine; Testosterone; and dafa#1 based on RNA-seq and microarray studies. WB:WBGene00019934 R07C12.4 Enriched in OLL and PVD based on microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Cadmium Chloride; cholesterol; and CGP37157 based on RNA-seq and microarray studies. WB:WBGene00019935 R07E4.1 Predicted to be involved in establishment of mitotic spindle orientation and regulation of establishment of bipolar cell polarity. Predicted to be located in spindle. Is an ortholog of human ANKFN1 (ankyrin repeat and fibronectin type III domain containing 1). WB:WBGene00019937 R07E4.3 Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 4. Is an ortholog of human UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII). WB:WBGene00019938 R07E4.5 Enriched in several structures, including ABplpaaaap; ABplpapapa; ABprpapapa; germ line; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including bisphenol A; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019939 lips-17 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00019940 npp-21 Predicted to be a structural constituent of nuclear pore. Predicted to be involved in mRNA export from nucleus and regulation of mitotic spindle assembly. Predicted to be part of nuclear pore. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder. Is an ortholog of human TPR (translocated promoter region, nuclear basket protein). WB:WBGene00019941 pgam-5 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in positive regulation of mitochondrial fission. Predicted to be located in mitochondrion. Expressed in neurons and pharynx. Is an ortholog of human PGAM5 (PGAM family member 5, mitochondrial serine/threonine protein phosphatase). WB:WBGene00019943 R07G3.7 Enriched in several structures, including ABplppppaa; ABprppppaa; RIH; germ line; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and clk-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including Zidovudine; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00019944 R07G3.8 Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be located in membrane. Expressed in dorsal nerve cord; ventral nerve cord; and vulva. Is an ortholog of human CYRIA (CYFIP related Rac1 interactor A) and CYRIB (CYFIP related Rac1 interactor B). WB:WBGene00019945 R08C7.1 Predicted to be located in membrane. WB:WBGene00019946 chat-1 Predicted to be involved in macromolecule localization. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Expressed in several structures, including intestine. Is an ortholog of human TMEM30A (transmembrane protein 30A). WB:WBGene00019947 htz-1 Predicted to enable DNA binding activity. Involved in negative regulation of DNA-templated transcription and negative regulation of cell fate specification. Located in condensed chromosome and nucleus. Part of chromatin. Expressed in several structures, including distal tip cell and somatic gonad. Is an ortholog of human H2AZ2 (H2A.Z variant histone 2). WB:WBGene00019948 R08C7.4 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00019949 R08C7.5 Enriched in germ line; seam cell; and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including hydrogen sulfide; methylmercuric chloride; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00019950 clec-175 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; methylmercuric chloride; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00019951 R08C7.8 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00019952 fbxb-74 Enriched in several structures, including ABalapppaa; MSpppaaa; RMEV; anterior ganglion (post); and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; proteomic; and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; rotenone; and indole based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019953 wapl-1 Enables cohesin unloader activity. Involved in positive regulation of double-strand break repair via homologous recombination. Located in germ cell nucleus. Is an ortholog of human WAPL (WAPL cohesin release factor). WB:WBGene00019954 R08C7.11 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; drh-3; and hlh-26 based on RNA-seq and microarray studies. Is affected by cadmium and Sirolimus based on microarray studies. WB:WBGene00019955 R08C7.12 Enriched in PHC; intestine; pm8; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and pmk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TDU repeat and Phosphorylation site. WB:WBGene00019956 fbxb-75 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; CEP socket cell; and amphid neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00019957 R08E3.1 Predicted to enable Notch binding activity. WB:WBGene00019959 R08E3.3 Predicted to enable cullin family protein binding activity. Predicted to be involved in positive regulation of ubiquitin-dependent protein catabolic process. Expressed in anterior gonad arm. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome 2. Is an ortholog of human CCDC22 (coiled-coil domain containing 22). WB:WBGene00019960 ztf-16 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in gonad development and positive regulation of gene expression. Located in nucleus. Expressed in accessory cell; gonad; hypodermis; and tail. Human ortholog(s) of this gene implicated in several diseases, including B-lymphoblastic leukemia/lymphoma; carcinoma (multiple); and common variable immunodeficiency 13. Is an ortholog of several human genes including IKZF1 (IKAROS family zinc finger 1); IKZF2 (IKAROS family zinc finger 2); and IKZF3 (IKAROS family zinc finger 3). WB:WBGene00019961 R08E5.1 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00019962 cysl-3 Enables cysteine synthase activity. Involved in cysteine biosynthetic process from serine. Predicted to be located in cytoplasm. WB:WBGene00019963 rips-1 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Expressed in hypodermis and intestine. WB:WBGene00019964 R08E5.4 Enriched in amphid sheath cell; body wall muscle cell; dopaminergic neurons; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; multi-walled carbon nanotube; and Atrazine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019965 R08F11.1 Predicted to enable beta-glucosidase activity. Predicted to be involved in carbohydrate metabolic process and glucosylceramide catabolic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 46. Is an ortholog of human GBA2 (glucosylceramidase beta 2). WB:WBGene00019966 srt-30 Predicted to be located in membrane. WB:WBGene00019967 cyp-33C8 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00019968 R08F11.4 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00019969 fpn-1.3 Enriched in germ line based on RNA-seq studies. Is affected by several genes including clk-1; daf-18; and unc-30 based on microarray and RNA-seq studies. Is affected by Colistin and dafa#1 based on microarray studies. WB:WBGene00019970 R08F11.7 Predicted to enable peroxidase activity. Involved in defense response to Gram-positive bacterium. WB:WBGene00019971 ergo-1 Enables DEAD/H-box RNA helicase binding activity and siRNA binding activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing and siRNA processing. Located in cytoplasm. WB:WBGene00019972 pei-2 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABplpppaaa; RID; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; D-glucose; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019973 R09A1.3 Enriched in head mesodermal cell and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00019974 R09A1.4 No description available WB:WBGene00019975 flp-34 Expressed in neurons and vulva. WB:WBGene00019976 fbxa-195 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on microarray and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00019977 fpn-1.2 Predicted to enable iron ion transmembrane transporter activity. Predicted to be involved in iron ion transmembrane transport. Predicted to be located in basolateral plasma membrane and lateral plasma membrane. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Is an ortholog of human SLC40A1 (solute carrier family 40 member 1). WB:WBGene00019978 hacd-1 Predicted to enable 3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. WB:WBGene00019979 R09B5.11 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. Expressed in seam cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Hirschsprung's disease; acanthosis nigricans; and brain disease (multiple). Is an ortholog of human SLC2A14 (solute carrier family 2 member 14) and SLC2A3 (solute carrier family 2 member 3). WB:WBGene00019980 chil-14 Predicted to enable oligosaccharide binding activity. Predicted to be located in endomembrane system. Is an ortholog of human CHID1 (chitinase domain containing 1). WB:WBGene00019981 srbc-59 Predicted to be located in membrane. WB:WBGene00019982 srbc-58 Predicted to be located in membrane. Expressed in neurons. WB:WBGene00019983 sti-1 Enables ATPase inhibitor activity; Hsp70 protein binding activity; and Hsp90 protein binding activity. Involved in determination of adult lifespan; reproduction; and response to heat. Located in cytoplasm. Expressed in several structures, including gonad; male-specific anatomical entity; pharyngeal muscle cell; touch receptor neurons; and vulva. Is an ortholog of human STIP1 (stress induced phosphoprotein 1). WB:WBGene00019984 R09E12.5 No description available WB:WBGene00019985 R09E12.6 No description available WB:WBGene00019986 R09F10.1 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSW (cathepsin W). WB:WBGene00019987 R09F10.3 Predicted to be located in nucleus. Predicted to be part of mediator complex. WB:WBGene00019988 R09F10.5 Predicted to be located in membrane. Expressed in gonadal sheath cell; head muscle; intestine; and neurons. WB:WBGene00019989 R09F10.8 Enriched in several structures, including ABplpappaa; ABplpppppp; ABprpppppp; germ line; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; iron oxide nanoparticle; and Alovudine based on RNA-seq; microarray; and proteomic studies. WB:WBGene00019990 R09H3.1 No description available WB:WBGene00019991 R09H3.3 Enriched in coelomocyte; germline precursor cell; neurons; and retrovesicular ganglion based on tiling array and microarray studies. Is affected by several genes including rrf-3; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00019992 R10A10.1 Predicted to be located in membrane. WB:WBGene00019993 rbx-2 Predicted to enable cullin family protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Predicted to be part of Cul5-RING ubiquitin ligase complex. Is an ortholog of human RNF7 (ring finger protein 7). WB:WBGene00019994 cdh-1 Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Van Maldergem syndrome 1 and mitral valve prolapse. Is an ortholog of human DCHS1 (dachsous cadherin-related 1) and DCHS2 (dachsous cadherin-related 2). WB:WBGene00019995 R10F2.4 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sek-1; pgl-1; and alg-1 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00019996 R10F2.5 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; alg-1; and glh-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Rifampin; Sirolimus; and Cry5B based on RNA-seq and microarray studies. Human OSCP1 enables transmembrane transporter activity. Is predicted to encode a protein with the following domains: Organic solute transport protein 1 and Organic solute carrier protein 1. Is an ortholog of human OSCP1 (organic solute carrier partner 1). WB:WBGene00019997 R10F2.6 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00019998 R10H1.1 Enriched in several structures, including anterior hypodermis; body wall musculature; interfacial epithelial cell; intestine; and rectal gland cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nine chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Coiled-coil domain-containing protein 50, N-terminal; Coiled-coil domain-containing protein 50 N-terminus; and Coiled-coil domain-containing protein 50. WB:WBGene00019999 srab-14 Expressed in ASEL and ASER. Is predicted to encode a protein with the following domains: Serpentine type 7TM GPCR receptor class ab chemoreceptor; 7TM GPCR, serpentine receptor class ab (Srab); and Phosphorylation site. WB:WBGene00020000 R10H1.3 No description available WB:WBGene00020003 R11E3.1 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00020004 R11E3.2 Predicted to enable L-ascorbic acid transmembrane transporter activity. Predicted to be involved in L-ascorbic acid transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC23A1 (solute carrier family 23 member 1) and SLC23A2 (solute carrier family 23 member 2). WB:WBGene00020005 R11E3.3 No description available WB:WBGene00020006 set-15 Involved in determination of adult lifespan. Expressed in intestine and neurons. WB:WBGene00020007 R11F4.1 Predicted to enable glycerol kinase activity. Predicted to be involved in glycerol metabolic process; phosphate-containing compound metabolic process; and triglyceride metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Is an ortholog of human GK (glycerol kinase); GK2 (glycerol kinase 2); and GK3 (glycerol kinase 3). WB:WBGene00020008 R11F4.2 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00020010 R11G1.1 Predicted to enable hormone binding activity. Predicted to be involved in receptor-mediated endocytosis. Predicted to be located in apical plasma membrane. Predicted to be part of receptor complex. WB:WBGene00020011 R11G1.2 Enriched in several structures, including PVR; accessory cell; germ line; hyp3; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pmk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including 1-methylnicotinamide; methylmercuric chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00020012 tmem-24 Located in plasma membrane. Is an ortholog of human C2CD2 (C2 calcium dependent domain containing 2) and C2CD2L (C2CD2 like). WB:WBGene00020013 R11G11.3 Enriched in neurons based on RNA-seq studies. Is affected by daf-12; rsr-2; and nfki-1 based on tiling array and RNA-seq studies. Is affected by fluoranthene and adsorbable organic bromine compound based on microarray studies. WB:WBGene00020014 srlf-19 Enriched in OLL; PVD; and pharyngeal muscle cell based on microarray and tiling array studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including 1-methylnicotinamide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00020015 nhr-210 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00020016 lipl-3 Predicted to enable hydrolase activity, acting on ester bonds. Involved in lipid catabolic process. Located in lysosome. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). WB:WBGene00020017 R12A1.3 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular space. Is an ortholog of human WFDC8 (WAP four-disulfide core domain 8). WB:WBGene00020018 R12B2.2 Predicted to be involved in Golgi organization and Golgi to plasma membrane protein transport. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human BLZF1 (basic leucine zipper nuclear factor 1). WB:WBGene00020019 R12B2.3 Enriched in several structures, including MSaaaaapa; MSaapaapa; germ line; neurons; and pm7 based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; manganese chloride; and metformin based on microarray and RNA-seq studies. WB:WBGene00020020 R12B2.6 Enriched in several structures, including ABplapaaaa; ABprapaaaa; Y cell; coelomocyte; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and mex-1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by atracurium; Oligosaccharides; and cadmium based on RNA-seq and microarray studies. WB:WBGene00020021 R12B2.7 Predicted to be located in membrane. WB:WBGene00020022 gldc-1 Predicted to enable glycine binding activity; glycine dehydrogenase (decarboxylating) activity; and pyridoxal phosphate binding activity. Predicted to be involved in glycine decarboxylation via glycine cleavage system. Predicted to be located in mitochondrion. Predicted to be part of glycine cleavage complex. Expressed in head. Human ortholog(s) of this gene implicated in glycine encephalopathy and stomach cancer. Is an ortholog of human GLDC (glycine decarboxylase). WB:WBGene00020023 frpr-16 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in BAG; command interneuron; and in male. WB:WBGene00020025 R12C12.5 Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and vesicle budding from membrane. Predicted to be located in cytoplasmic side of plasma membrane and multivesicular body. Predicted to be part of ESCRT III complex. Expressed in germ line. Is an ortholog of human CHMP4A (charged multivesicular body protein 4A). WB:WBGene00020026 R12C12.6 Predicted to be located in lysosomal membrane. Expressed in excretory cell; hermaphrodite gonad; and rectal valve cell. Is an ortholog of human TMEM9B (TMEM9 domain family member B). WB:WBGene00020027 R12C12.7 Enriched in germ line; intestine; muscle cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by five chemicals including D-glucose; stavudine; and paraquat based on RNA-seq and microarray studies. WB:WBGene00020028 R12C12.8 Enriched in AVA; germ line; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including dpy-10; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Alovudine; stavudine; and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00020029 R12C12.9 Predicted to be located in membrane. WB:WBGene00020030 kel-20 Enriched in ABalapppaa; ABplpppaaa; ABprpppaaa; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; sek-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including rotenone; Cry5B; and Alovudine based on RNA-seq and microarray studies. Human KLHL20 Contributes to ubiquitin-protein transferase activity. Human KLHL20 enables type II interferon binding activity. Is predicted to encode a protein with the following domains: BTB/POZ domain; BTB-kelch protein; BTB And C-terminal Kelch; Kelch-type beta propeller; Kelch motif; BTB/Kelch-associated; SKP1/BTB/POZ domain superfamily; and Kelch repeat type 1. Is an ortholog of human KLHL20 (kelch like family member 20). WB:WBGene00020031 suco-1 Predicted to be located in cytoplasm and membrane. Expressed widely. Is an ortholog of human SUCO (SUN domain containing ossification factor). WB:WBGene00020032 R12E2.6 Enriched in NSM and body wall muscle cell based on tiling array studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including aldicarb; sodium arsenite; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00020033 R12E2.7 Expressed in several structures, including P5.ppal; P5.ppar; P7.papl; enteric muscle; and vulC. WB:WBGene00020034 R12E2.8 Enriched in several structures, including ABaraapapaa; ABaraapppaa; MSaaaaapa; MSaapaapa; and pharyngeal gland cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and elt-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00020035 egg-5 Enables protein kinase binding activity. Involved in cortical actin cytoskeleton organization; female gamete generation; and positive regulation of protein localization to cell cortex. Located in cell cortex and nucleus. Expressed in oocyte. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Is an ortholog of human PTPRG (protein tyrosine phosphatase receptor type G) and PTPRZ1 (protein tyrosine phosphatase receptor type Z1). WB:WBGene00020036 R12E2.11 Enables orotate phosphoribosyltransferase activity. Involved in UMP biosynthetic process. Expressed in body wall musculature; spermatheca; and vulval muscle. Human ortholog(s) of this gene implicated in orotic aciduria and purine-pyrimidine metabolic disorder. Is an ortholog of human UMPS (uridine monophosphate synthetase). WB:WBGene00020037 mrps-6 Predicted to enable small ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS6 (mitochondrial ribosomal protein S6). WB:WBGene00020038 R12E2.13 Involved in innate immune response. Acts upstream of or within IRE1-mediated unfolded protein response. Is an ortholog of human SDF2 (stromal cell derived factor 2). WB:WBGene00020039 R12E2.14 Enriched in carbon dioxide sensory neurons; germline precursor cell; hypodermis; intestine; and rectal epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-five chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00020040 R12E2.15 Enriched in several structures, including carbon dioxide sensory neurons; cholinergic neurons; germline precursor cell; pharyngeal muscle cell; and tail hypodermis based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by thirty-three chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00020041 R13A1.1 Enriched in AVE; excretory cell; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including clk-1; hpl-2; and dpy-21 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00020042 R13A1.3 Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00020043 R13A1.5 Enriched in ABplppppaa; ABprppppaa; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; sek-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00020045 glb-23 Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Expressed in head neurons; lateral nerve cord; ventral cord neurons; and ventral nerve cord. WB:WBGene00020046 best-16 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00020047 ttr-32 Predicted to be located in cell surface and extracellular region. WB:WBGene00020048 lgc-12 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in mechanosensory neurons. WB:WBGene00020049 ttr-8 Predicted to be located in cell surface and extracellular region. WB:WBGene00020050 R13A5.7 Enriched in head mesodermal cell; intestine; and male-specific anatomical entity based on RNA-seq and microarray studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020051 mfsd-6 Acts upstream of or within with a positive effect on synaptic vesicle exocytosis. Located in synaptic vesicle. Is an ortholog of human MFSD6 (major facilitator superfamily domain containing 6). WB:WBGene00020052 R13A5.10 Predicted to enable guanosine deaminase activity. Predicted to be involved in purine nucleoside catabolic process. WB:WBGene00020053 R13A5.11 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00020054 R13D7.2 Enriched in AMshL; AMshR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; bisphenol A; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00020055 srt-6 Predicted to be located in membrane. WB:WBGene00020056 R13D11.1 Predicted to be located in membrane. WB:WBGene00020057 R13D11.3 Predicted to be located in membrane. WB:WBGene00020058 R13D11.4 Predicted to enable N-acetyltransferase activity. WB:WBGene00020059 srab-15 Is affected by let-418; hpl-2; and etr-1 based on RNA-seq studies. Is affected by Diazinon based on microarray studies. WB:WBGene00020060 srab-16 Located in non-motile cilium. Expressed in AWBL; AWBR; AWCL; and AWCR. WB:WBGene00020061 R13D11.7 No description available WB:WBGene00020062 nhr-270 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00020063 R13D11.10 Enriched in dopaminergic neurons; head mesodermal cell; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including clk-1; nhr-25; and pry-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Tunicamycin; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00020064 kbp-1 Involved in kinetochore assembly. Located in kinetochore. WB:WBGene00020065 clec-159 Expressed in head and tail. WB:WBGene00020066 dhhc-5 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Expressed in excretory cell and intestine. WB:WBGene00020067 clec-158 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including multi-walled carbon nanotube; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00020068 cra-1 Predicted to be involved in DNA metabolic process; chromosome segregation; and meiotic cell cycle. Predicted to be located in cytoplasm. Predicted to be part of NatB complex. Is an ortholog of human NAA25 (N-alpha-acetyltransferase 25, NatB auxiliary subunit). WB:WBGene00020069 R13H7.2 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in neurons. WB:WBGene00020070 rmd-6 Predicted to enable microtubule binding activity. Predicted to be located in mitochondrion; mitotic spindle pole; and spindle microtubule. Is an ortholog of human RMDN3 (regulator of microtubule dynamics 3). WB:WBGene00020071 ttbk-2.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00020072 R13H9.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00020073 sdz-28 Involved in gastrulation. WB:WBGene00020074 R52.2 No description available WB:WBGene00020075 math-35 Expressed in intestine. WB:WBGene00020076 R52.4 Enriched in ABplppppaa; ABprppppaa; and NSM based on tiling array and single-cell RNA-seq studies. Is affected by rsr-2; eat-2; and sir-2.1 based on tiling array and microarray studies. Is affected by Microcystin-LR based on microarray studies. WB:WBGene00020077 R52.5 Enriched in ABplppppaa and ABprppppaa based on single-cell RNA-seq studies. Is affected by several genes including clk-1; csr-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including Ag nanoparticles; cadmium; and tetrabromobisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00020078 R52.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including csr-1; mex-3; and hda-1 based on tiling array and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00020080 math-37 Enriched in AFD and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00020081 sdz-29 Is affected by several genes including daf-2; eat-2; and tph-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020082 gcp-2.1 Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Is an ortholog of human FOLH1 (folate hydrolase 1); NAALAD2 (N-acetylated alpha-linked acidic dipeptidase 2); and NAALADL1 (N-acetylated alpha-linked acidic dipeptidase like 1). WB:WBGene00020083 R57.2 Enriched in ADE sheath cell; hypodermis; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00020084 R105.1 Predicted to be located in extracellular space. WB:WBGene00020086 npr-24 Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in bipolar disorder. Is an ortholog of human SSTR2 (somatostatin receptor 2); SSTR4 (somatostatin receptor 4); and SSTR5 (somatostatin receptor 5). WB:WBGene00020087 R119.1 Enriched in germ line; germline precursor cell; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and clk-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including manganese chloride; D-glucose; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00020088 R119.2 Predicted to enable aminopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nephronophthisis-like nephropathy 1. Is an ortholog of human XPNPEP3 (X-prolyl aminopeptidase 3). WB:WBGene00020089 R119.3 Located in mitochondrion. WB:WBGene00020090 R119.5 Predicted to enable protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. Predicted to be involved in protein modification process. Predicted to be located in cytoplasm. Is an ortholog of human PCMTD1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1) and PCMTD2 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2). WB:WBGene00020091 rnp-8 Enables enzyme binding activity; poly(G) binding activity; and polynucleotide adenylyltransferase activator activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Located in protein-containing complex. Expressed in germ line and oocyte. WB:WBGene00020092 pcf-11 Predicted to enable RNA polymerase II complex binding activity and mRNA binding activity. Predicted to be involved in mRNA polyadenylation and termination of RNA polymerase II transcription. Predicted to be located in cytoplasm. Predicted to be part of mRNA cleavage factor complex. Is an ortholog of human PCF11 (PCF11 cleavage and polyadenylation factor subunit). WB:WBGene00020093 R144.3 Predicted to be located in mitochondrion. WB:WBGene00020094 wip-1 Enables cytoskeletal regulatory protein binding activity. Involved in embryonic body morphogenesis; regulation of cell migration; and regulation of protein stability. Expressed in hypodermis. Is an ortholog of human WIPF1 (WAS/WASL interacting protein family member 1); WIPF2 (WAS/WASL interacting protein family member 2); and WIPF3 (WAS/WASL interacting protein family member 3). WB:WBGene00020095 smcr-8 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in autophagy. Predicted to be located in cytoplasm. Predicted to be part of guanyl-nucleotide exchange factor complex. Is an ortholog of human SMCR8 (SMCR8-C9orf72 complex subunit). WB:WBGene00020096 R144.6 Predicted to enable carbohydrate transmembrane transporter activity. Predicted to be involved in carbohydrate transmembrane transport. Predicted to be located in membrane. Is an ortholog of human TMEM144 (transmembrane protein 144). WB:WBGene00020097 larp-1 Enables poly(G) binding activity and poly(U) RNA binding activity. Predicted to be involved in positive regulation of translation. Located in P-body. Expressed in germ line; head; and tail. Is an ortholog of human LARP1 (La ribonucleoprotein 1, translational regulator) and LARP1B (La ribonucleoprotein 1B). WB:WBGene00020098 R144.10 Expressed in head and tail. WB:WBGene00020099 R144.11 Predicted to be located in membrane. Expressed in head. Is an ortholog of human TMEM177 (transmembrane protein 177). WB:WBGene00020100 mks-1 Expressed in neurons. Used to study Meckel syndrome. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 13; Joubert syndrome 28; and Meckel syndrome 1. Is predicted to encode a protein with the following domains: Ciliary basal body-associated, B9 protein and B9-type C2 domain. Is an ortholog of human MKS1 (MKS transition zone complex subunit 1). WB:WBGene00020101 lmtr-5 Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to amino acid stimulus and positive regulation of TORC1 signaling. Predicted to be located in lysosome. Predicted to be part of Ragulator complex. Is an ortholog of human LAMTOR5 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 5). WB:WBGene00020102 R148.3 Expressed in body wall musculature; neurons; and pharynx. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020103 R148.4 Predicted to be located in membrane. WB:WBGene00020104 R148.5 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; anterior hypodermis; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PTB/PI domain and Phosphorylation site. WB:WBGene00020105 R148.7 Enriched in several structures, including DVA; amphid sheath cell; germ line; intestine; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00020106 R151.1 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. WB:WBGene00020107 R151.2 Predicted to enable ATP binding activity and ribose phosphate diphosphokinase activity. Predicted to be involved in 5-phosphoribose 1-diphosphate biosynthetic process and purine nucleotide biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of ribose phosphate diphosphokinase complex. Expressed in head; somatic gonad precursor; somatic nervous system; and tail. Human ortholog(s) of this gene implicated in several diseases, including Arts syndrome; X-linked deafness 1; and X-linked recessive disease (multiple). Is an ortholog of human PRPS1 (phosphoribosyl pyrophosphate synthetase 1); PRPS1L1 (phosphoribosyl pyrophosphate synthetase 1 like 1); and PRPS2 (phosphoribosyl pyrophosphate synthetase 2). WB:WBGene00020109 der-2 Predicted to enable misfolded protein binding activity; signal recognition particle binding activity; and ubiquitin-specific protease binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of Hrd1p ubiquitin ligase ERAD-L complex. Is an ortholog of human DERL2 (derlin 2). WB:WBGene00020110 hsp-75 Predicted to enable protein kinase binding activity and unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human TRAP1 (TNF receptor associated protein 1). WB:WBGene00020111 R151.8 Predicted to enable chromatin binding activity. Predicted to be involved in pattern specification process. Predicted to be located in nucleus. Is an ortholog of human CRAMP1 (cramped chromatin regulator homolog 1). WB:WBGene00020112 pfd-5 Predicted to enable unfolded protein binding activity. Predicted to be involved in RNA polymerase I assembly; RNA polymerase II core complex assembly; and RNA polymerase III assembly. Predicted to be located in cytoplasm. Predicted to be part of prefoldin complex. Expressed in body wall musculature; head muscle; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human PFDN5 (prefoldin subunit 5). WB:WBGene00020113 R151.10 Predicted to enable phosphatase activity. Located in sarcoplasmic reticulum. Is an ortholog of human PUDP (pseudouridine 5'-phosphatase). WB:WBGene00020114 pde-4 Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity. Involved in several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway; and sleep. Located in synapse. Expressed in DD neuron and VD neuron. Human ortholog(s) of this gene implicated in acrodysostosis. Is an ortholog of human PDE4B (phosphodiesterase 4B). WB:WBGene00020115 mboa-6 Predicted to enable 1-acylglycerophosphocholine O-acyltransferase activity and lysophospholipid acyltransferase activity. Involved in glycerophospholipid biosynthetic process; positive regulation of growth rate; and post-embryonic development. Predicted to be located in endoplasmic reticulum and membrane. Expressed in pharyngeal muscle cell and tail. Is an ortholog of human LPCAT3 (lysophosphatidylcholine acyltransferase 3). WB:WBGene00020116 moa-1 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00020117 R155.3 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00020118 R155.4 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; antimycin; and glycine based on microarray and RNA-seq studies. WB:WBGene00020119 R160.2 Predicted to be located in membrane. WB:WBGene00020120 R160.3 Predicted to be located in membrane. WB:WBGene00020121 R160.4 Predicted to be located in membrane. WB:WBGene00020122 R160.5 Predicted to be located in membrane. WB:WBGene00020123 R160.6 Predicted to be located in membrane. WB:WBGene00020124 R173.2 No description available WB:WBGene00020125 cest-19 Predicted to be located in membrane. WB:WBGene00020126 flp-26 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in M1 neuron; interneuron; tail; and in male. WB:WBGene00020127 R193.1 Is affected by several genes including eat-2; hrde-1; and smn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by resveratrol and adsorbable organic bromine compound based on microarray studies. WB:WBGene00020128 R193.2 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Bethlem myopathy; Ullrich congenital muscular dystrophy; and dystonia 27. Is an ortholog of human COL6A3 (collagen type VI alpha 3 chain). WB:WBGene00020129 R193.3 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by four chemicals including metformin; Sirolimus; and fluoranthene based on RNA-seq and microarray studies. WB:WBGene00020130 igcm-2 Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in cell-cell junction. Expressed in several structures, including PVT; gonad; head neurons; intestine; and pharynx. Is an ortholog of human IGSF9 (immunoglobulin superfamily member 9). WB:WBGene00020131 gcy-28 Enables guanylate cyclase activity. Involved in chemotaxis; olfactory behavior; and sensory perception. Located in cell body and neuron projection. Expressed in body wall musculature; gonad; hypodermis; intestine; and neurons. Human ortholog(s) of this gene implicated in artery disease (multiple) and bone development disease (multiple). Is an ortholog of human NPR1 (natriuretic peptide receptor 1). WB:WBGene00020134 T01B6.1 Enriched in several structures, including ABalppppapa; ABaraapapaa; anterior arcade cell; head mesodermal cell; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Suppressor APC domain-containing protein 1/2 and Adenomatous polyposis coli tumour suppressor protein. Is an ortholog of human SAPCD2 (suppressor APC domain containing 2). WB:WBGene00020135 aakg-4 Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleotide-activated protein kinase complex. Expressed in several structures, including accessory cell; dorsal nerve cord; neurons; non-striated muscle; and preanal ganglion. WB:WBGene00020136 nlp-45 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00020137 T01B10.5 Predicted to be located in membrane. WB:WBGene00020138 T01B11.1 Predicted to be located in membrane. WB:WBGene00020139 eppl-1 Predicted to enable lyase activity; pyridoxal phosphate binding activity; and transaminase activity. Expressed in PQR; amphid neurons; and hypodermis. Is an ortholog of human ETNPPL (ethanolamine-phosphate phospho-lyase) and PHYKPL (5-phosphohydroxy-L-lysine phospho-lyase). WB:WBGene00020140 ant-1.4 Predicted to enable ATP:ADP antiporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Located in mitochondrion. Expressed in amphid sensillum; body wall musculature; rectal gland cell; somatic nervous system; and vulval muscle. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6). WB:WBGene00020141 lmd-5 Predicted to enable chitin binding activity and hydrolase activity, acting on glycosyl bonds. Predicted to be involved in carbohydrate metabolic process and rejection of self pollen. WB:WBGene00020142 aak-2 Enables AMP-activated protein kinase activity. Involved in several processes, including determination of adult lifespan; pharyngeal pumping; and regulation of protein secretion. Located in axon; cytoplasm; and neuronal cell body. Expressed in several structures, including body wall musculature; excretory canal; interfacial epithelial cell; neurons; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; colon cancer; and type 2 diabetes mellitus. Is an ortholog of human PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1) and PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2). WB:WBGene00020143 T01C8.2 Predicted to be located in membrane. WB:WBGene00020144 T01C8.3 Enriched in intestine and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including manganese chloride; multi-walled carbon nanotube; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00020145 got-1.1 Is affected by several genes including daf-12; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by dafa#1; Sirolimus; and allantoin based on microarray studies. WB:WBGene00020146 got-1.2 Enables L-aspartate:2-oxoglutarate aminotransferase activity. Involved in positive regulation of glutamate metabolic process. Located in cytoplasm. Expressed in head; neurons; and tail. Human ortholog(s) of this gene implicated in several diseases, including amyotrophic lateral sclerosis; pancreatic ductal adenocarcinoma; and transient cerebral ischemia. Is an ortholog of human GOT1 (glutamic-oxaloacetic transaminase 1). WB:WBGene00020148 T01D1.3 Predicted to enable protein phosphatase 1 binding activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be located in nucleus. WB:WBGene00020149 T01D1.4 Predicted to enable acireductone dioxygenase [iron(II)-requiring] activity. Predicted to be involved in methionine metabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human ADI1 (acireductone dioxygenase 1). WB:WBGene00020150 T01D1.5 Predicted to be located in membrane. WB:WBGene00020151 T01G6.1 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00020152 nhr-211 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00020153 nhr-212 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00020154 T01G6.10 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00020155 T02B11.3 Expressed in AMshL; AMshR; amphid sheath cell; and phasmid sheath cell. WB:WBGene00020156 T02B11.4 Enriched in PLM and amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including nicotinic acid; rotenone; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00020157 T02B11.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00020158 T02C5.1 Predicted to be located in membrane. WB:WBGene00020160 igcm-3 Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in adherens junction. Expressed in arcade cell; hypodermis; pharyngeal muscle cell; spermatheca; and vulva. WB:WBGene00020163 T02G5.3 Predicted to be involved in positive regulation of protein localization to ciliary membrane. Predicted to be located in ciliary membrane. Predicted to be part of plasma membrane protein complex. Is an ortholog of human EFCAB7 (EF-hand calcium binding domain 7). WB:WBGene00020164 T02G5.4 Enriched in germ line; intestine; and muscle cell based on RNA-seq and microarray studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including manganese chloride; D-glucose; and bisphenol S based on RNA-seq; proteomic; and microarray studies. WB:WBGene00020165 T02G5.5 No description available WB:WBGene00020166 T02G5.7 Predicted to enable acetyl-CoA C-acetyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in arteriosclerosis; beta-ketothiolase deficiency; and carbohydrate metabolic disorder. Is an ortholog of human ACAT1 (acetyl-CoA acetyltransferase 1). WB:WBGene00020167 T02G5.11 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Heme; rotenone; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00020168 mct-5 Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in cataract 47; familial hyperinsulinemic hypoglycemia 7; and lymphangioleiomyomatosis. Is an ortholog of human SLC16A12 (solute carrier family 16 member 12) and SLC16A8 (solute carrier family 16 member 8). WB:WBGene00020169 mmaa-1 Predicted to enable GTPase activity. Predicted to be located in cytoplasm. Used to study methylmalonic acidemia. Human ortholog(s) of this gene implicated in methylmalonic acidemia cblA type. Is an ortholog of human MMAA (metabolism of cobalamin associated A). WB:WBGene00020170 T02G5.14 Enriched in several structures, including ABalaaaarl; accessory cell; body wall muscle cell from C lineage; intestinal muscle; and rectal muscle based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including 1-methylnicotinamide; rotenone; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00020171 T02H6.1 Predicted to enable snoRNA binding activity. Predicted to be part of small-subunit processome. Is an ortholog of human RRP9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein). WB:WBGene00020172 thoc-1 Predicted to be involved in mRNA export from nucleus and regulation of DNA-templated transcription elongation. Predicted to be part of THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness. Is an ortholog of human THOC1 (THO complex subunit 1). WB:WBGene00020173 T02H6.3 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and unc-30 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including aldicarb; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00020174 T02H6.4 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00020175 T02H6.5 Enriched in RIC; excretory cell; and rectal epithelial cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-18; and csr-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Alovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00020176 T02H6.6 Is affected by several genes including mex-3; ain-1; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and dibromoacetic acid based on RNA-seq and microarray studies. WB:WBGene00020177 T02H6.7 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00020178 T02H6.8 Enriched in NSM based on tiling array studies. Is affected by several genes including eat-2; mex-3; and mex-1 based on tiling array; RNA-seq; and microarray studies. Is affected by methylmercuric chloride; atracurium; and allantoin based on microarray and RNA-seq studies. WB:WBGene00020179 T02H6.9 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00020180 T02H6.10 Is affected by rsr-2; eat-2; and eri-1 based on tiling array; RNA-seq; and microarray studies. Is affected by tryptophan; Atrazine; and Sirolimus based on microarray studies. WB:WBGene00020181 T02H6.11 Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 3. Is an ortholog of human UQCRB (ubiquinol-cytochrome c reductase binding protein). WB:WBGene00020182 ugt-53 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00020183 T03D3.5 Enriched in PLML; PLMR; body wall muscle cell; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and pie-1 based on RNA-seq; microarray; and proteomic studies. Is affected by eleven chemicals including 1-methylnicotinamide; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020184 uba-5 Enables UFM1 activating enzyme activity and ubiquitin conjugating enzyme binding activity. Involved in determination of adult lifespan; reproduction; and stress response to metal ion. Predicted to be located in cytosol. Used to study early infantile epileptic encephalopathy. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 24 and developmental and epileptic encephalopathy 44. Is an ortholog of human UBA5 (ubiquitin like modifier activating enzyme 5). WB:WBGene00020185 pgk-1 Predicted to enable ADP binding activity; ATP binding activity; and phosphoglycerate kinase activity. Predicted to be involved in gluconeogenesis; glycolytic process; and phosphorylation. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in hemolytic anemia and phosphoglycerate kinase 1 deficiency. Is an ortholog of human PGK2 (phosphoglycerate kinase 2). WB:WBGene00020186 T03F1.4 No description available WB:WBGene00020187 gsp-4 Predicted to enable protein serine/threonine phosphatase activity. Involved in regulation of pseudopodium assembly and reproductive process. Located in cytoplasm and pseudopodium. Part of chromatin. Expressed in ILsoDL; ILsoVL; anal sphincter muscle; intestine; and sperm. WB:WBGene00020188 T03F1.6 Enriched in several structures, including ABalaaaarl; amphid neurons; male distal tip cell; mechanosensory neurons; and pharyngeal muscle cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and clk-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; rotenone; and stavudine based on microarray and RNA-seq studies. WB:WBGene00020189 tfbm-1 Predicted to enable mitochondrial transcription factor activity and rRNA (adenine-N6,N6-)-dimethyltransferase activity. Predicted to be involved in rRNA methylation and transcription initiation at mitochondrial promoter. Predicted to be located in mitochondrial matrix. Is an ortholog of human TFB1M (transcription factor B1, mitochondrial). WB:WBGene00020190 guk-1 Predicted to enable guanylate kinase activity. Predicted to be involved in GDP metabolic process; GMP metabolic process; and phosphorylation. Predicted to be located in cytosol. Expressed in anchor cell. Is an ortholog of human GUK1 (guanylate kinase 1). WB:WBGene00020191 clec-53 Predicted to enable signaling receptor activity. Human ortholog(s) of this gene implicated in Alzheimer's disease; autoimmune disease (multiple); and cholangiocarcinoma. Is an ortholog of human REG1A (regenerating family member 1 alpha). WB:WBGene00020192 T03F1.11 Predicted to enable calcium ion binding activity. WB:WBGene00020193 T03F1.12 Predicted to be involved in Golgi to endosome transport; Golgi to plasma membrane protein transport; and protein localization to Golgi apparatus. Predicted to be located in trans-Golgi network. Is an ortholog of human SYS1 (SYS1 golgi trafficking protein). WB:WBGene00020194 T03G6.1 Enriched in head mesodermal cell; hypodermis; intestine; and sensory neurons based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-nine chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: YitH/HolE, acetyltransferase (GNAT) domain and Acetyltransferase (GNAT) domain. WB:WBGene00020195 T03G6.3 Located in I band and striated muscle dense body. Expressed in vulval muscle. Is an ortholog of human ENPP6 (ectonucleotide pyrophosphatase/phosphodiesterase 6). WB:WBGene00020196 zchc-1A Predicted to enable metal ion binding activity. Is an ortholog of human ZC2HC1A (zinc finger C2HC-type containing 1A) and ZC2HC1B (zinc finger C2HC-type containing 1B). WB:WBGene00020197 mans-3 Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in Rafiq syndrome. Is an ortholog of human MAN1B1 (mannosidase alpha class 1B member 1). WB:WBGene00020199 metl-9 Predicted to enable protein-L-histidine N-pros-methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human METTL9 (methyltransferase 9, His-X-His N1(pi)-histidine). WB:WBGene00020200 T04A6.1 Predicted to be located in membrane. Expressed in anal sphincter muscle. WB:WBGene00020201 T04A6.2 Predicted to be located in membrane. WB:WBGene00020202 T04A6.3 Enriched in several structures, including Z1.p; Z4.a; male distal tip cell; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and isp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; Cry5B; and cholesterol based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Nematode trypsin-6-like family; Cytosolic motility protein; and Chymotrypsin family Peptidase-S1. WB:WBGene00020203 T04B8.1 Enriched in AVG and motor neurons based on single-cell RNA-seq studies. Is affected by several genes including sir-2.1; alg-1; and mex-3 based on RNA-seq and microarray studies. Is affected by five chemicals including paraquat; resveratrol; and tetrabromobisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Vitelline membrane outer layer protein I (VOMI) superfamily. WB:WBGene00020204 T04B8.2 Enriched in pharynx based on microarray studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Psoralens; and metformin based on RNA-seq and microarray studies. WB:WBGene00020205 arrd-1 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. WB:WBGene00020207 T04B8.5 Predicted to enable potassium:chloride symporter activity. Predicted to be involved in cell volume homeostasis; chloride transmembrane transport; and inorganic ion homeostasis. Predicted to be located in membrane. Is an ortholog of human SLC12A9 (solute carrier family 12 member 9). WB:WBGene00020208 fnip-2 Predicted to enable ATPase inhibitor activity and protein-folding chaperone binding activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human FNIP1 (folliculin interacting protein 1) and FNIP2 (folliculin interacting protein 2). WB:WBGene00020209 T04C9.1 Predicted to enable GTPase activator activity. Predicted to be involved in signal transduction. Predicted to be located in cytoplasm. Expressed in head. Human ortholog(s) of this gene implicated in X-linked mental retardation with cerebellar hypoplasia and distinctive facial appearance; acute myelomonocytic leukemia; and juvenile myelomonocytic leukemia. Is an ortholog of several human genes including ARHGAP10 (Rho GTPase activating protein 10); ARHGAP26 (Rho GTPase activating protein 26); and OPHN1 (oligophrenin 1). WB:WBGene00020210 T04C9.2 Predicted to be located in membrane. WB:WBGene00020211 T04C9.3 Enriched in AFD and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-12; hpl-2; and egl-43 based on microarray; tiling array; and RNA-seq studies. WB:WBGene00020212 T04D1.2 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalapppaa; ABalpapppa; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00020214 attf-5 Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of mediator complex. Expressed widely. WB:WBGene00020215 T04G9.4 Predicted to enable holo-[acyl-carrier-protein] synthase activity. Predicted to be involved in lysine biosynthetic process via aminoadipic acid. Predicted to be located in cytosol. Is an ortholog of human AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase). WB:WBGene00020216 trap-2 Predicted to be located in endoplasmic reticulum membrane. Expressed in several structures, including hypodermis and muscle cell. Is an ortholog of human SSR2 (signal sequence receptor subunit 2). WB:WBGene00020217 T04G9.6 Enriched in ABaraapapaa; ABaraapppaa; Caapa; PVR; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including pgl-1; csr-1; and fbf-1 based on RNA-seq and microarray studies. Is affected by tryptophan; allantoin; and Sirolimus based on microarray studies. WB:WBGene00020218 T04G9.7 Enriched in several structures, including XXX cell; germ line; gonadal sheath cell; head mesodermal cell; and interfacial epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by sixteen chemicals including Heme; hydrogen sulfide; and rotenone based on microarray and RNA-seq studies. WB:WBGene00020219 T05A7.1 Enriched in several structures, including ABplapapppp; ABprapapppp; body wall muscle cell from MS lineage; germ line; and rectal epithelial cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00020220 clec-140 Enriched in cephalic sheath cell; intestine; and neurons based on tiling array and microarray studies. Is affected by several genes including eat-2; sir-2.1; and pmk-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00020221 T05A7.3 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and AFD based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pmk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily and CUB domain. WB:WBGene00020222 fut-6 Enables alpha-(1->3)-fucosyltransferase activity. Involved in fucosylation. Predicted to be located in Golgi cisterna membrane. Is an ortholog of human FUT7 (fucosyltransferase 7). WB:WBGene00020223 T05A7.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00020224 T05A7.7 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABplaapaaa; neuronal sheath cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including rotenone; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Growth factor receptor cysteine-rich domain superfamily. WB:WBGene00020225 sre-40 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00020227 T05A8.1 Enriched in DA neuron; VA neuron; and hypodermis based on tiling array studies. Is affected by several genes including skn-1; eat-2; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including aldicarb; methylmercuric chloride; and metformin based on microarray and RNA-seq studies. WB:WBGene00020228 T05A8.2 Predicted to be located in membrane. WB:WBGene00020229 T05A8.3 Enriched in head mesodermal cell; neurons; retrovesicular ganglion; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00020230 nep-2 Predicted to enable metalloendopeptidase activity. Involved in olfactory learning and regulation of chemotaxis. Located in cell surface. Expressed in GLR and body wall musculature. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Charcot-Marie-Tooth disease axonal type 2T; X-linked dominant hypophosphatemic rickets; and cerebellar ataxia type 43. Is an ortholog of human MME (membrane metalloendopeptidase) and MMEL1 (membrane metalloendopeptidase like 1). WB:WBGene00020231 wdr-31 Enriched in several structures, including ABarpapaapp; ABplaaaaapp; ABplapppapp; ABprapppapp; and ciliated neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: WD40 repeat; WD domain, G-beta repeat; WD40-repeat-containing domain superfamily; WD repeat-containing protein 31; WD40/YVTN repeat-like-containing domain superfamily; and G-protein beta WD-40 repeat. Is an ortholog of human WDR31 (WD repeat domain 31). WB:WBGene00020232 T05A8.6 Enriched in male-specific anatomical entity based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and aak-2 based on RNA-seq and microarray studies. Is affected by six chemicals including methylmercuric chloride; sodium arsenite; and sucrose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00020233 T05A8.7 Predicted to be located in membrane. WB:WBGene00020234 T05A12.3 Enriched in germ line; rectal epithelial cell; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by four chemicals including D-glucose; stavudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020235 T05A12.4 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in DNA damage response. Is an ortholog of human SHPRH (SNF2 histone linker PHD RING helicase). WB:WBGene00020236 lgc-1 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00020237 phat-4 Involved in pharyngeal gland morphogenesis. Expressed in g1AL; g1AR; g1P; g2L; and g2R. WB:WBGene00020238 T05B4.4 Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00020239 T05B4.8 Enriched in g1AL; g1AR; g1P; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Tunicamycin; and deoxynivalenol based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00020240 T05B4.9 Enriched in g1AL; g1AR; and g1P based on single-cell RNA-seq studies. Is affected by several genes including clk-1; lin-15B; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Tunicamycin; multi-walled carbon nanotube; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00020241 T05B4.10 Enriched in g1P based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by Tunicamycin; resveratrol; and Atrazine based on microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00020242 phat-5 Involved in pharyngeal gland morphogenesis. Expressed in g1AL and g1AR. WB:WBGene00020243 T05B4.12 Enriched in cephalic sheath cell; dopaminergic neurons; g1P; and pharynx based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-29 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00020244 T05B4.13 Expressed in g1AL; g1AR; g1P; g2L; and g2R. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00020245 T05B11.1 Enriched in several structures, including anterior hypodermis; enteric muscle; neurons; rectal muscle; and terminal bulb based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by fourteen chemicals including 1-methylnicotinamide; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00020246 clic-1 Predicted to enable clathrin heavy chain binding activity. Predicted to be involved in clathrin-dependent endocytosis. Located in periciliary membrane compartment. Expressed in head. Is an ortholog of human CLTA (clathrin light chain A). WB:WBGene00020247 T05B11.4 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00020248 T05C1.1 Enriched in amphid sheath cell; head mesodermal cell; hypodermis; mechanosensory neurons; and pm6 based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; RNA-seq; and tiling array studies. Is affected by fourteen chemicals including tryptophan; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00020249 T05C1.2 Predicted to enable peptidase activity. Predicted to be involved in proteolysis. WB:WBGene00020250 T05C1.3 Enriched in several structures, including NSM; PLM; amphid sheath cell; germline precursor cell; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by sixteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00020251 camt-1 Enables chromatin binding activity. Involved in positive chemotaxis; positive regulation of transcription by RNA polymerase II; and response to oxygen levels. Located in nucleus. Part of chromatin. Human ortholog(s) of this gene implicated in nonprogressive cerebellar ataxia with mental retardation. Is an ortholog of human CAMTA2 (calmodulin binding transcription activator 2). WB:WBGene00020252 T05C1.5 Enriched in ABplpppppp and ABprpppppp based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and nhr-49 based on microarray and RNA-seq studies. Is affected by four chemicals including indole; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: CC domain; ShK domain-like; and ShKT domain. WB:WBGene00020254 T05C3.2 Enriched in OLQDL; OLQDR; OLQVL; OLQVR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and daf-12 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by eleven chemicals including Tunicamycin; multi-walled carbon nanotube; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: WD40 repeat; WD domain, G-beta repeat; P-loop containing nucleoside triphosphate hydrolase; Domain of unknown function (DUF4062); Quinoprotein alcohol dehydrogenase-like superfamily; Domain of unknown function DUF4062; NACHT nucleoside triphosphatase; NACHT domain; and WD40/YVTN repeat-like-containing domain superfamily. Is an ortholog of human NWD2 (NACHT and WD repeat domain containing 2). WB:WBGene00020255 T05C3.3 No description available WB:WBGene00020256 T05C3.6 Predicted to enable catalytic activity. Predicted to be located in membrane. WB:WBGene00020258 T05E7.1 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in disease of metabolism. Is an ortholog of several human genes including ACOT2 (acyl-CoA thioesterase 2); ACOT4 (acyl-CoA thioesterase 4); and BAAT (bile acid-CoA:amino acid N-acyltransferase). WB:WBGene00020259 T05E7.3 Predicted to be involved in organelle organization and regulation of actin nucleation. Predicted to be located in endosome. Predicted to be part of WASH complex. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome 1 and hereditary spastic paraplegia 8. Is an ortholog of human WASHC5 (WASH complex subunit 5). WB:WBGene00020260 T05E7.4 Predicted to be located in membrane. WB:WBGene00020261 vet-1 Enriched in AWC; MC neuron; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00020262 ferl-1 Enriched in ABalapppaa and I5 neuron based on single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020263 let-355 Predicted to enable double-stranded RNA binding activity and helicase activity. Predicted to be involved in positive regulation of transcription by RNA polymerase I. Predicted to be located in nucleolus. Used to study obesity. Is an ortholog of human DHX33 (DEAH-box helicase 33). WB:WBGene00020264 acl-8 Predicted to enable acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Predicted to be located in endoplasmic reticulum. Is an ortholog of human LCLAT1 (lysocardiolipin acyltransferase 1). WB:WBGene00020265 fbxa-196 Enriched in neurons and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by fourteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00020266 T05H4.3 Enriched in neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; pgl-1; and alg-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily; U2A'/phosphoprotein 32 family A, C-terminal; Leucine-rich repeat, typical subtype; and Leucine-rich repeat. Is an ortholog of human LRRC9 (leucine rich repeat containing 9). WB:WBGene00020267 T05H4.4 Predicted to enable FAD binding activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in estrogen-receptor negative breast cancer and methemoglobinemia. Is an ortholog of human CYB5R1 (cytochrome b5 reductase 1) and CYB5R3 (cytochrome b5 reductase 3). WB:WBGene00020268 hpo-19 Predicted to enable FAD binding activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in estrogen-receptor negative breast cancer and methemoglobinemia. Is an ortholog of human CYB5R1 (cytochrome b5 reductase 1); CYB5R2 (cytochrome b5 reductase 2); and CYB5R3 (cytochrome b5 reductase 3). WB:WBGene00020269 erfa-1 Predicted to enable sequence-specific mRNA binding activity and translation release factor activity, codon specific. Predicted to be involved in cytoplasmic translational termination. Predicted to be located in cytosol. Predicted to be part of translation release factor complex. Is an ortholog of human ETF1 (eukaryotic translation termination factor 1). WB:WBGene00020270 cht-6 Predicted to enable chitinase activity. Predicted to be involved in cell wall macromolecule catabolic process and chitin catabolic process. WB:WBGene00020271 T05H4.8 Is affected by set-25; met-2; and eat-2 based on RNA-seq and microarray studies. Is affected by Ethanol and Microcystin-LR based on RNA-seq and microarray studies. WB:WBGene00020272 T05H4.9 No description available WB:WBGene00020273 urb-1 Enriched in several structures, including ABalpapppa; ABarapappa; ABplpppapa; ABprpppapa; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq; proteomic; and microarray studies. Is affected by thirteen chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Human URB1 enables RNA binding activity. Is predicted to encode a protein with the following domains: Nucleolar pre-ribosomal-associated protein 1, C-terminal domain; Armadillo-type fold; Nucleolar pre-ribosomal-associated protein 1; and Armadillo-like helical. Is an ortholog of human URB1 (URB1 ribosome biogenesis homolog). WB:WBGene00020274 T05H4.11 Enriched in several structures, including ABalapaaaa; ABalappaap; cephalic sheath cell; ciliated neurons; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and gld-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; Zidovudine; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00020275 atp-4 Predicted to enable proton transmembrane transporter activity. Predicted to be involved in proton motive force-driven ATP synthesis and proton transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex. Human ortholog(s) of this gene implicated in essential hypertension. Is an ortholog of human ATP5PF (ATP synthase peripheral stalk subunit F6). WB:WBGene00020276 T05H4.15 Enriched in coelomocyte; head mesodermal cell; interfacial epithelial cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box protein she-1-like. WB:WBGene00020277 T06A1.1 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00020279 glb-25 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00020280 T06A1.5 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00020281 T06A4.1 Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; familial febrile seizures 11; and familial temporal lobe epilepsy 5. Is an ortholog of human CPA6 (carboxypeptidase A6). WB:WBGene00020282 mps-3 Enables potassium channel regulator activity. Involved in regulation of chemotaxis and regulation of potassium ion transport. Predicted to be located in membrane. Expressed in ADF; lumbar neurons; and pharyngeal neurons. WB:WBGene00020283 T06A4.3 Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Is an ortholog of human CPA6 (carboxypeptidase A6). WB:WBGene00020284 mel-46 Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in P granule. Predicted to be part of SMN complex. Expressed in germ line. Is an ortholog of human DDX20 (DEAD-box helicase 20). WB:WBGene00020285 T06A10.2 Enriched in intestine and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including daf-16; lin-15B; and met-2 based on RNA-seq and microarray studies. Is affected by four chemicals including rotenone; Tunicamycin; and paraquat based on RNA-seq and microarray studies. WB:WBGene00020286 gtsf-1 Predicted to enable metal ion binding activity. Located in cytoplasm. Is an ortholog of human GTSF1 (gametocyte specific factor 1). WB:WBGene00020287 lsy-13 Predicted to enable methylated histone binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Is an ortholog of human ING4 (inhibitor of growth family member 4). WB:WBGene00020288 srt-73 Predicted to be located in membrane. WB:WBGene00020289 T06C10.3 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00020290 T06D4.1 Predicted to enable endonuclease activity. WB:WBGene00020291 T06D4.2 Enriched in NSM and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and mes-4 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020292 nep-19 Enriched in male based on RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; antimycin; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00020293 nep-20 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 5D. Is an ortholog of human ECEL1 (endothelin converting enzyme like 1) and KEL (Kell metallo-endopeptidase (Kell blood group)). WB:WBGene00020294 T06F4.1 Predicted to be located in membrane. WB:WBGene00020295 pqbp-1.2 Expressed in intestine. WB:WBGene00020296 rrp-8 Predicted to enable methylated histone binding activity. Predicted to be involved in cellular response to glucose starvation; rDNA heterochromatin formation; and regulation of transcription by glucose. Predicted to be located in nucleolus. Predicted to be part of chromatin silencing complex and rDNA heterochromatin. Expressed widely. Is an ortholog of human RRP8 (ribosomal RNA processing 8). WB:WBGene00020297 nog-1 Predicted to enable GTPase activity and RNA binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of lipid storage; and regulation of reproductive process. Located in nucleolus. Expressed in several structures, including excretory cell; germ cell; intestine; pharynx; and vulva. Is an ortholog of human GTPBP4 (GTP binding protein 4). WB:WBGene00020298 uncp-18 Predicted to enable syntaxin binding activity. Predicted to be involved in intracellular protein transport; neurotransmitter secretion; and vesicle docking involved in exocytosis. Predicted to be located in plasma membrane and secretory granule. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 5. Is an ortholog of human STXBP2 (syntaxin binding protein 2) and STXBP3 (syntaxin binding protein 3). WB:WBGene00020299 T07A9.12 Predicted to be involved in intracellular calcium ion homeostasis. Predicted to be located in endoplasmic reticulum. Is an ortholog of human TMEM203 (transmembrane protein 203). WB:WBGene00020300 ssna-1 Enriched in several structures, including ABaraapapp; ABaraapppp; anterior hypodermis; germ line; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including rotenone; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020301 gid-2 Predicted to enable metal ion binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of GID complex. Expressed in E; Ea; and Ep. Is an ortholog of human RMND5A (required for meiotic nuclear division 5 homolog A). WB:WBGene00020302 T07D1.3 Predicted to be located in membrane. Expressed in mechanosensory neurons. WB:WBGene00020304 fbxa-200 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; D-glucose; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00020305 T07D3.2 Enriched in AVKL and AVKR based on single-cell RNA-seq studies. Is affected by several genes including age-1; daf-12; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by cadmium based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00020306 T07D3.3 Is affected by several genes including daf-12; tdc-1; and drh-3 based on tiling array and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00020307 T07D3.4 Enriched in several structures, including AVE; cephalic sheath cell; head mesodermal cell; mechanosensory neurons; and rectal gland cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including diallyl trisulfide; mianserin; and stavudine based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Human FKTN enables phosphotransferase activity, for other substituted phosphate groups. Is predicted to encode a protein with the following domain: Ribitol-5-phosphate transferase FKTN-related. Is an ortholog of human FKTN (fukutin). WB:WBGene00020308 T07D3.5 Enriched in CEPshDL; CEPshDR; CEPshVL; CEPshVR; and body wall muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; elt-2; and dpy-7 based on tiling array; RNA-seq; and microarray studies. Is affected by stavudine; Rifampin; and adsorbable organic bromine compound based on RNA-seq and microarray studies. WB:WBGene00020309 T07D3.6 Is affected by several genes including eat-2; dpy-7; and aak-2 based on RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00020310 T07D3.8 No description available WB:WBGene00020311 T07D3.9 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human ACOT9 (acyl-CoA thioesterase 9). WB:WBGene00020312 T07E3.1 No description available WB:WBGene00020313 T07E3.2 Predicted to be located in membrane. WB:WBGene00020314 T07E3.3 Predicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in mitochondrion and peroxisome. WB:WBGene00020315 T07E3.4 Enriched in muscle cell; sensory neurons; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by sixteen chemicals including methylmercuric chloride; Tunicamycin; and levamisole based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00020316 brc-2 Enables single-stranded DNA binding activity. Involved in several processes, including DNA metabolic process; egg-laying behavior; and embryo development. Located in condensed nuclear chromosome. WB:WBGene00020317 pdf-1 Involved in several processes, including locomotory behavior; parturition; and positive regulation of protein secretion. Predicted to be located in extracellular region. Expressed in neurons and rectum. WB:WBGene00020318 T07F8.1 Enriched in cholinergic neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and csr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Sodium Chloride; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1280) and Protein of unknown function DUF1280. WB:WBGene00020319 npr-31 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Huntington's disease and type 2 diabetes mellitus. Is an ortholog of several human genes including APLNR (apelin receptor); MTNR1A (melatonin receptor 1A); and MTNR1B (melatonin receptor 1B). WB:WBGene00020320 T07F8.4 Predicted to enable histone deacetylase binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Expressed in gonad; pharynx; and spermatheca. Is an ortholog of human MIER1 (MIER1 transcriptional regulator). WB:WBGene00020321 T07F12.1 Enables acid phosphatase activity. Located in cytosol. Is an ortholog of human UBASH3A (ubiquitin associated and SH3 domain containing A). WB:WBGene00020322 T07F12.2 Enriched in germ line; intestine; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; Zidovudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: PA domain superfamily. Is an ortholog of human PRADC1 (protease associated domain containing 1). WB:WBGene00020323 arrd-23 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. WB:WBGene00020324 T07F12.4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including autophagy; axon extension; and positive regulation of autophagy. Predicted to be located in autophagosome; cytosol; and phagophore assembly site membrane. WB:WBGene00020325 bath-46 Enriched in AFD and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; let-60; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercury hydroxide; bisphenol A; and Cadmium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00020326 math-38 Involved in defense response to Gram-positive bacterium. WB:WBGene00020327 clec-21 Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00020328 clec-20 Is affected by several genes including daf-2; let-60; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including methylmercuric chloride; sucrose; and stearic acid based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain. WB:WBGene00020329 bath-26 Enriched in RIB; excretory system; head mesodermal cell; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including tryptophan; methylmercury hydroxide; and bisphenol A based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily; MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00020330 cest-16 Predicted to be located in membrane. WB:WBGene00020333 sre-12 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00020334 epg-7 Enables molecular adaptor activity. Involved in positive regulation of macroautophagy. Located in cytoplasm. Expressed in neurons; pharyngeal muscle cell; and tail. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human RB1CC1 (RB1 inducible coiled-coil 1). WB:WBGene00020335 ttr-30 Predicted to be located in cell surface and extracellular region. WB:WBGene00020338 T08A9.6 Enriched in excretory cell and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Lithium Chloride; Zidovudine; and metformin based on microarray and RNA-seq studies. WB:WBGene00020339 ttr-59 Predicted to be located in cell surface; extracellular region; and membrane. WB:WBGene00020340 T08B1.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00020341 T08B1.4 Predicted to be involved in lipid metabolic process. WB:WBGene00020342 fbxa-201 Enriched in ABalpapaap; ABarappaap; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Tunicamycin; antimycin; and glycine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain and HTH domain in Mos1 transposase. WB:WBGene00020343 acs-3 Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Expressed in several structures, including excretory cell; intestine; seam cell; tail; and vulva. WB:WBGene00020345 T08B2.4 Enriched in several structures, including germ line; hyp3; neurons; rectal epithelial cell; and rectum based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00020346 rbm-5 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Expressed in CAN; head neurons; intestinal cell; muscle cell; and ventral nerve cord. Human ortholog(s) of this gene implicated in TARP syndrome; gastrointestinal system cancer (multiple); and lung adenocarcinoma. Is an ortholog of human RBM10 (RNA binding motif protein 10) and RBM5 (RNA binding motif protein 5). WB:WBGene00020347 ech-1.2 Predicted to enable enoyl-CoA hydratase activity and long-chain-3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial fatty acid beta-oxidation multienzyme complex. Expressed in tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; fatty liver disease; and mitochondrial trifunctional protein deficiency. Is an ortholog of human HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha). WB:WBGene00020348 mrpl-23 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL23 (mitochondrial ribosomal protein L23). WB:WBGene00020349 T08B2.11 Expressed in head neurons and intestine. WB:WBGene00020350 T08B2.12 Enriched in CEP socket cell; muscle cell; sperm; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-three chemicals including Ethanol; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00020351 T08B6.1 Enriched in ABplppaapa; ABprppaapa; and AVE based on tiling array and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube; cadmium; and adsorbable organic bromine compound based on RNA-seq and microarray studies. WB:WBGene00020352 T08B6.2 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; paraquat; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00020353 T08B6.4 Predicted to be located in membrane. WB:WBGene00020354 sgnh-1 Predicted to enable poly(A) binding activity. Predicted to be located in nucleus. WB:WBGene00020356 T08B6.9 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-two chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq; microarray; and proteomic studies. WB:WBGene00020357 T08E11.1 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including methylmercury hydroxide; methylmercuric chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00020358 math-39 Enriched in intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00020359 math-40 Enriched in FLP; GABAergic neurons; OLL; PVD; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including D-glucopyranose; antimycin; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00020360 math-41 Enriched in OLL; PVD; dopaminergic neurons; head mesodermal cell; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including D-glucopyranose; sesamin; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; TRAF-like; MATH domain; and Phosphorylation site. WB:WBGene00020361 fbxc-19 Enriched in several structures, including ABalaaaala; RMED; ciliated neurons; intestinal muscle; and rectal muscle based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00020362 fbxb-10 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalaapppa; ABalapaaaa; and ciliated neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including rotenone; mianserin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00020363 fbxa-3 Enriched in several structures, including ABalaaaarl; ABalaaaarr; MSpaapaa; coelomocyte; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Sodium Chloride; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00020364 T08E11.8 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00020365 T08G2.2 Predicted to be located in membrane. WB:WBGene00020366 acdh-10 Predicted to enable medium-chain-acyl-CoA dehydrogenase activity. Predicted to be involved in medium-chain fatty acid catabolic process. Located in mitochondrion. Expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in medium chain acyl-CoA dehydrogenase deficiency. Is an ortholog of human ACADM (acyl-CoA dehydrogenase medium chain). WB:WBGene00020368 ast-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including neuron differentiation; pharynx morphogenesis; and regulation of nematode male tail tip morphogenesis. Located in nucleus. Expressed in intestine; neurons; and rectal gland cell. Human ortholog(s) of this gene implicated in myeloid leukemia; pulmonary venoocclusive disease; and thrombocytopenia. Is an ortholog of human FLI1 (Fli-1 proto-oncogene, ETS transcription factor). WB:WBGene00020369 exc-15 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. WB:WBGene00020370 T08H10.3 Predicted to be located in membrane. WB:WBGene00020371 oac-60 Is affected by several genes including pgl-1; csr-1; and glh-1 based on microarray and RNA-seq studies. Is affected by Tunicamycin; Ag nanoparticles; and Atrazine based on microarray and RNA-seq studies. WB:WBGene00020372 T09A12.1 Enriched in several structures, including ABplaapapa; ABpraapapa; MSaaaaapa; MSaapaapa; and pharyngeal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00020373 gpx-6 Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple) and spondylometaphyseal dysplasia Sedaghatian type. Is an ortholog of human GPX4 (glutathione peroxidase 4). WB:WBGene00020374 serp-1.2 Predicted to be involved in endoplasmic reticulum unfolded protein response. Predicted to be located in endoplasmic reticulum. Is an ortholog of human SERP1 (stress associated endoplasmic reticulum protein 1) and SERP2 (stress associated endoplasmic reticulum protein family member 2). WB:WBGene00020375 pigv-1 Predicted to enable mannosyltransferase activity. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of mannosyltransferase complex. Expressed in excretory cell; hypodermis; intestine; pharynx; and rectal epithelium. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 1. Is an ortholog of human PIGV (phosphatidylinositol glycan anchor biosynthesis class V). WB:WBGene00020376 T09B4.2 Predicted to enable ATPase activator activity. Predicted to be involved in membrane organization. Predicted to be located in membrane. WB:WBGene00020377 T09B4.3 Enriched in amphid sheath cell; body wall muscle cell; head mesodermal cell; pharyngeal muscle cell; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including manganese chloride; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00020378 T09B4.4 Predicted to enable calcium ion binding activity. Is an ortholog of human CALML4 (calmodulin like 4). WB:WBGene00020379 T09B4.5 Predicted to be located in membrane. WB:WBGene00020380 T09B4.6 Enriched in several structures, including ABplpppppp; ABprpppppp; MSpaapaa; intestine; and pharynx based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Mercuric Chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: BTG-like domain superfamily. WB:WBGene00020381 T09B4.7 Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including Mercuric Chloride; D-glucose; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00020382 T09B4.8 Predicted to enable alanine-glyoxylate transaminase activity. Predicted to be involved in L-alanine catabolic process, by transamination and glyoxylate catabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); atrial fibrillation; and mild cognitive impairment. Is an ortholog of human AGXT2 (alanine--glyoxylate aminotransferase 2). WB:WBGene00020383 tin-44 Predicted to enable protein-folding chaperone binding activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Expressed in tail. Human ortholog(s) of this gene implicated in proliferative diabetic retinopathy. Is an ortholog of human TIMM44 (translocase of inner mitochondrial membrane 44). WB:WBGene00020384 T09D3.3 Enriched in NSM; g2L; g2R; and pm6 based on tiling array and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and lin-35 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00020385 nhr-216 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00020386 dach-1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestinal cell. WB:WBGene00020387 T10B5.1 No description available WB:WBGene00020388 T10B5.2 Enriched in Z1.p; Z4.a; male distal tip cell; somatic gonad precursor; and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; methylmercuric chloride; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00020389 T10B5.3 Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Is an ortholog of human WDR43 (WD repeat domain 43). WB:WBGene00020390 T10B5.4 Predicted to enable N-acetyltransferase activity. WB:WBGene00020391 cct-7 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Expressed in anchor cell; head; non-striated muscle; and tail. Is an ortholog of human CCT7 (chaperonin containing TCP1 subunit 7). WB:WBGene00020392 knl-3 Involved in several processes, including chromosome organization; positive regulation of cell cycle process; and positive regulation of kinetochore assembly. Located in kinetochore. WB:WBGene00020393 T10B5.7 Predicted to be involved in lipid metabolic process. WB:WBGene00020394 T10B5.8 Predicted to enable FMN binding activity and oxidoreductase activity. WB:WBGene00020395 T10B5.9 No description available WB:WBGene00020396 T10B5.10 Predicted to enable DNA binding activity and metal ion binding activity. WB:WBGene00020397 pcbd-1 Predicted to enable 4-alpha-hydroxytetrahydrobiopterin dehydratase activity. Predicted to be involved in tetrahydrobiopterin biosynthetic process. Expressed in head; hypodermis; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia D. Is an ortholog of human PCBD1 (pterin-4 alpha-carbinolamine dehydratase 1). WB:WBGene00020398 cerk-1 Predicted to enable ceramide kinase activity. Predicted to be involved in ceramide metabolic process and phosphorylation. Human ortholog(s) of this gene implicated in retinitis pigmentosa 26. Is an ortholog of human CERK (ceramide kinase). WB:WBGene00020399 ztf-4 Predicted to enable RNA binding activity. Expressed in body wall musculature; egg-laying apparatus; neurons; and pharynx. Human ortholog(s) of this gene implicated in atherosclerosis and cervical cancer. Is an ortholog of several human genes including HNRNPC (heterogeneous nuclear ribonucleoprotein C); RALY (RALY heterogeneous nuclear ribonucleoprotein); and RALYL (RALY RNA binding protein like). WB:WBGene00020400 T10B11.4 Enriched in ADEshL; ADEshR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by eight chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00020401 T10B11.5 Predicted to be located in nuclear outer membrane. Human ortholog(s) of this gene implicated in craniotubular dysplasia Ikegawa type. Is an ortholog of human TMEM53 (transmembrane protein 53). WB:WBGene00020402 T10B11.6 Located in mitochondrion. Expressed in distal tip cell; intestinal muscle; rectal epithelial cell; and ventral nerve cord. Human ortholog(s) of this gene implicated in craniotubular dysplasia Ikegawa type. Is an ortholog of human TMEM53 (transmembrane protein 53). WB:WBGene00020403 hrde-4 Predicted to be involved in regulatory ncRNA-mediated gene silencing. WB:WBGene00020404 T10B11.8 Enriched in several structures, including ABalppppppp; GLR; RIC; germ line; and head mesodermal cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020406 T10D4.1 Is affected by several genes including eat-2; alg-1; and csr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00020407 chil-24 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. WB:WBGene00020408 T10D4.6 Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be located in cytoplasm. WB:WBGene00020409 T10D4.7 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including D-glucose; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00020410 T10D4.11 Is affected by several genes including let-60; sir-2.1; and tdp-1 based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00020411 T10E9.1 Enriched in several structures, including ABalpapppa; ABalppappa; ABarapappa; GLR; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including manganese chloride; Zidovudine; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box protein she-1-like and F-box domain. WB:WBGene00020412 T10E9.2 Enriched in several structures, including ABalapaaaa; ABalappapa; ABalpapppa; GLR; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including manganese chloride; D-glucose; and Linolenic Acids based on RNA-seq and microarray studies. WB:WBGene00020413 cpg-22 Enriched in accessory cell and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twenty-one chemicals including hydrogen sulfide; nicotinic acid; and manganese chloride based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: DOMON domain. WB:WBGene00020414 T10E9.4 Predicted to be located in membrane. WB:WBGene00020415 T10E9.5 Predicted to be located in membrane. WB:WBGene00020416 T10E9.6 Predicted to be located in membrane. WB:WBGene00020417 nuo-2 Predicted to enable NADH dehydrogenase (ubiquinone) activity. Involved in determination of adult lifespan. Located in mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease and nuclear type mitochondrial complex I deficiency 8. Is an ortholog of human NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3). WB:WBGene00020418 T10E9.8 Predicted to be located in membrane. WB:WBGene00020419 acdh-4 Predicted to enable acyl-CoA dehydrogenase activity. Predicted to be located in mitochondrion. Is an ortholog of human ACADSB (acyl-CoA dehydrogenase short/branched chain). WB:WBGene00020420 npr-38 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00020421 chtb-3 Predicted to enable chitin binding activity. WB:WBGene00020422 T10F2.2 Predicted to enable L-ornithine transmembrane transporter activity. Predicted to be involved in mitochondrial L-ornithine transmembrane transport. Predicted to be located in mitochondrion. Expressed in tail. Human ortholog(s) of this gene implicated in citrullinemia and ornithine translocase deficiency. Is an ortholog of human SLC25A15 (solute carrier family 25 member 15) and SLC25A2 (solute carrier family 25 member 2). WB:WBGene00020423 prp-19 Predicted to enable ubiquitin protein ligase activity. Involved in nuclear mRNA surveillance. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Prp19 complex and U2-type catalytic step 1 spliceosome. Is an ortholog of human PRPF19 (pre-mRNA processing factor 19). WB:WBGene00020424 T10H9.1 Predicted to be located in membrane. WB:WBGene00020425 syx-18 Predicted to be involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in endoplasmic reticulum. Predicted to be part of SNARE complex. Is an ortholog of human STX18 (syntaxin 18). WB:WBGene00020426 T10H10.2 Predicted to enable flavin-dependent sulfhydryl oxidase activity and protein disulfide isomerase activity. Predicted to be involved in protein folding. Predicted to be located in extracellular space. Is an ortholog of human QSOX1 (quiescin sulfhydryl oxidase 1) and QSOX2 (quiescin sulfhydryl oxidase 2). WB:WBGene00020427 sav-1 Predicted to enable molecular adaptor activity. Predicted to be involved in hippo signaling; negative regulation of cell population proliferation; and positive regulation of apoptotic process. Predicted to be located in cytosol. Is an ortholog of human SAV1 (salvador family WW domain containing protein 1). WB:WBGene00020428 irld-48 Is affected by several genes including sir-2.1; ain-1; and etr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00020430 irld-49 Enriched in neurons based on RNA-seq studies. Is affected by several genes including elt-2; rrf-1; and dpy-21 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00020431 irld-50 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including elt-2; sir-2.1; and csr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by tryptophan based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00020432 hpa-2 Is affected by clk-1 based on microarray studies. WB:WBGene00020433 T11F8.1 Predicted to be located in membrane. WB:WBGene00020434 T11F8.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including skn-1; glp-1; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00020435 T11F8.4 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00020436 amdh-1 Predicted to enable imidazolonepropionase activity. Predicted to be involved in histidine catabolic process. Predicted to be located in cytoplasm. Is an ortholog of human AMDHD1 (amidohydrolase domain containing 1). WB:WBGene00020437 stt-3 Predicted to enable dolichyl-diphosphooligosaccharide-protein glycotransferase activity. Predicted to be involved in post-translational protein modification. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ix. Is an ortholog of human STT3B (STT3 oligosaccharyltransferase complex catalytic subunit B). WB:WBGene00020438 T12A2.3 Enriched in several structures, including ABarppaapp; ABarpppapp; somatic nervous system; tail neurons; and vulval muscle based on Chronogram and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00020439 T12A2.5 Enriched in germ line; neurons; and in male based on proteomic and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and pgl-1 based on tiling array and RNA-seq studies. Is affected by eight chemicals including tryptophan; 1-methylnicotinamide; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00020440 T12A2.6 Enriched in RID based on RNA-seq studies. Is affected by several genes including let-60; hpl-2; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine and Chlorpyrifos based on microarray studies. WB:WBGene00020441 bcas-2 Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of Prp19 complex and catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human BCAS2 (BCAS2 pre-mRNA processing factor). WB:WBGene00020442 gen-1 Enables crossover junction DNA endonuclease activity. Involved in DNA damage response and negative regulation of nematode larval development. Predicted to be located in cytoplasm and nucleus. WB:WBGene00020443 esyt-2 Expressed in body wall musculature; gonad; nervous system; neurons; and pharynx. Human ESYT2 enables calcium ion binding activity; identical protein binding activity; and phospholipid binding activity. Is predicted to encode a protein with the following domains: Synaptotagmin-like mitochondrial-lipid-binding domain; Synaptotagmin, SMP domain; C2 domain superfamily; and C2 domain. Is an ortholog of human ESYT2 (extended synaptotagmin 2). WB:WBGene00020444 ptp-8 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in cilium assembly. Predicted to be located in cytoplasm. Is an ortholog of human PTPDC1 (protein tyrosine phosphatase domain containing 1). WB:WBGene00020445 T12B3.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00020446 T12B3.3 Predicted to enable glycerophosphodiester phosphodiesterase activity. Predicted to be involved in N-acylethanolamine metabolic process; ethanolamine metabolic process; and phospholipid metabolic process. Predicted to be located in plasma membrane. Is an ortholog of human GDE1 (glycerophosphodiester phosphodiesterase 1). WB:WBGene00020447 mob-3 Predicted to enable protein kinase activator activity. Predicted to be involved in positive regulation of protein phosphorylation and signal transduction. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human MOB3A (MOB kinase activator 3A) and MOB3B (MOB kinase activator 3B). WB:WBGene00020448 fbxa-51 Enriched in several structures, including ABalppppppp; ABplaapappp; ABpraaapppp; rectal epithelial cell; and rectum based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including levamisole; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00020449 fbxa-54 Enriched in head neurons; intestine; and mechanosensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00020450 fbxa-10 Enriched in ALNL; ALNR; hypodermis; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and sek-1 based on microarray and RNA-seq studies. Is affected by six chemicals including stavudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00020451 fbxa-11 Enriched in AVE; Z1.p; Z4.a; body wall muscle cell; and male distal tip cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by Cry5B and bortezomib based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00020452 fbxa-22 Is affected by hpl-2 and rsr-2 based on tiling array studies. Is affected by tetrabromobisphenol A based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00020453 fbxa-55 Enriched in AFD; ASER; and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00020454 fbxa-56 Is affected by drh-3; eat-2; and set-2 based on RNA-seq and microarray studies. Is affected by cadmium based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00020455 fbxa-59 Involved in innate immune response. WB:WBGene00020456 fbxa-60 Involved in innate immune response. Acts upstream of or within PERK-mediated unfolded protein response. WB:WBGene00020457 fbxa-67 Enriched in several structures, including ABplapaaapa; ABplppppaa; ABprapaaapa; ABprppppaa; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including bisphenol A; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00020458 fbxa-70 Is affected by several genes including daf-16; daf-12; and hsf-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00020459 fbxa-23 Enriched in several structures, including ABalapapap; ABalapppap; ABalpapppa; ABarapappa; and AVK based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including age-1; lin-4; and eat-2 based on microarray and RNA-seq studies. WB:WBGene00020460 nhr-273 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00020461 T12C9.7 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in mitotic cell cycle phase transition. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin A2-CDK2 complex. WB:WBGene00020462 ari-2 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2). WB:WBGene00020463 cec-6 Predicted to enable chromatin binding activity and methylated histone binding activity. Predicted to be involved in chromatin organization and negative regulation of transcription by RNA polymerase II. Predicted to be part of pericentric heterochromatin. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); glioblastoma; and hematologic cancer (multiple). Is an ortholog of human CBX6 (chromobox 6); CBX7 (chromobox 7); and CBX8 (chromobox 8). WB:WBGene00020464 tebp-2 Predicted to enable DNA binding activity. WB:WBGene00020465 T12E12.6 Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Involved in embryo development; regulation of egg-laying behavior; and regulation of meiotic cell cycle process involved in oocyte maturation. Predicted to be located in cytoplasm. WB:WBGene00020466 sld-2 Expressed in several structures, including ABa; EMS; Psub1; Psub2; and germ line. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020467 T12F5.2 Predicted to be located in membrane. WB:WBGene00020468 T13A10.1 Predicted to be located in membrane. WB:WBGene00020469 T13A10.2 Predicted to enable metal ion binding activity. WB:WBGene00020471 pho-14 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Expressed in anal depressor muscle; body wall musculature; and intestinal muscle. WB:WBGene00020472 lips-11 Predicted to enable lipase activity. Involved in IRE1-mediated unfolded protein response. WB:WBGene00020473 lips-12 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00020474 lips-13 Predicted to enable lipase activity. Predicted to be involved in lipid catabolic process. WB:WBGene00020475 sut-1 Located in cytoplasm and nucleus. Expressed in several structures, including germ cell; neurons; and somatic cell. Used to study tauopathy. WB:WBGene00020476 T13B5.9 Predicted to enable peptidase activity. Predicted to be involved in cell adhesion and proteolysis. Predicted to be located in cytoplasm. WB:WBGene00020478 T13C2.2 Enriched in accessory cell; anterior hypodermis; arc ant V; neurons; and pharyngeal muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by fourteen chemicals including multi-walled carbon nanotube; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00020479 T13C2.3 Enriched in GABAergic neurons; head mesodermal cell; male-specific anatomical entity; and muscle cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00020480 ssup-72 Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Involved in regulation of locomotion. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Expressed in hypodermis; intestine; and nervous system. Is an ortholog of several human genes including SSU72 (SSU72 homolog, RNA polymerase II CTD phosphatase); SSU72L3 (SSU72 like 3); and SSU72L6 (SSU72 like 6). WB:WBGene00020481 gldi-2 Predicted to enable calcium ion binding activity. Predicted to be involved in endocytosis. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autistic disorder; and cerebellar ataxia, mental retardation and dysequlibrium syndrome. Is an ortholog of human LDLR (low density lipoprotein receptor); LRP8 (LDL receptor related protein 8); and VLDLR (very low density lipoprotein receptor). WB:WBGene00020482 T13C2.7 Predicted to be located in membrane. WB:WBGene00020483 T13C5.2 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by methylmercuric chloride; multi-walled carbon nanotube; and glycine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00020484 T13C5.3 Enriched in germline precursor cell; hypodermis; mechanosensory neurons; and ventral cord blast cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; let-60; and daf-12 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercury hydroxide; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00020485 ceh-54 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in neurons. Is an ortholog of several human genes including ESX1 (ESX homeobox 1); RHOXF1 (Rhox homeobox family member 1); and RHOXF2 (Rhox homeobox family member 2). WB:WBGene00020486 T13C5.6 Predicted to enable sphingosine-1-phosphate phosphatase activity. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. Is an ortholog of human PLPP6 (phospholipid phosphatase 6) and PLPP7 (phospholipid phosphatase 7 (inactive)). WB:WBGene00020487 T13C5.7 Enriched in hyp4; hyp5; hyp6; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Zidovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00020488 T13G4.1 Enriched in ABplpppapa and ABprpppapa based on single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: GYF domain and GYF-like domain superfamily. WB:WBGene00020489 hot-8 Predicted to be involved in olfactory behavior and response to odorant. Predicted to be located in axon and neuronal cell body. WB:WBGene00020490 tmc-1 Enables sodium channel activity. Involved in detection of stimulus involved in sensory perception; monoatomic ion transmembrane transport; and sensory perception of chemical stimulus. Located in neuronal cell body; non-motile cilium; and plasma membrane. Expressed in body wall musculature and neurons. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 36; autosomal recessive nonsyndromic deafness 7; and sensorineural hearing loss. Is an ortholog of human TMC3 (transmembrane channel like 3). WB:WBGene00020491 T13G4.4 Predicted to enable S-adenosylmethionine-homocysteine S-methyltransferase activity. Predicted to be involved in S-methylmethionine cycle and methionine biosynthetic process. WB:WBGene00020492 T13G4.5 Enriched in Z1.p; Z4.a; gon_male_dtc anterior; and gon_male_dtc posterior based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on RNA-seq; proteomic; and microarray studies. Is affected by five chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00020494 T13G4.7 Predicted to be part of ribonucleoprotein complex. WB:WBGene00020496 spat-3 Enables histone ubiquitin ligase activity. Involved in several processes, including negative regulation of gene expression, epigenetic; negative regulation of vulval development; and nematode male tail tip morphogenesis. Predicted to be part of PcG protein complex and ubiquitin ligase complex. Expressed in several structures, including AIYL; AIYR; SMDDL; and SMDDR. Used to study developmental disorder of mental health. Human ortholog(s) of this gene implicated in Luo-Schoch-Yamamoto syndrome and pancreatic ductal carcinoma. Is an ortholog of human RING1 (ring finger protein 1) and RNF2 (ring finger protein 2). WB:WBGene00020497 T14A8.2 Enriched in BAG; PVR; dopaminergic neurons; germline precursor cell; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00020498 T14B4.1 Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. Is an ortholog of human TARBP1 (TAR (HIV-1) RNA binding protein 1). WB:WBGene00020499 mrps-18.C Predicted to enable small ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS18C (mitochondrial ribosomal protein S18C). WB:WBGene00020500 T14B4.3 Predicted to enable signaling receptor activity. Predicted to be involved in positive regulation of Wnt signaling pathway. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in X-linked parkinsonism-spasticity syndrome; congenital disorder of glycosylation type II; and syndromic X-linked intellectual disability Hedera type. Is an ortholog of human ATP6AP2 (ATPase H+ transporting accessory protein 2). WB:WBGene00020501 T14B4.5 Predicted to be located in membrane. WB:WBGene00020502 T14B4.8 Enriched in several structures, including germ line; head mesodermal cell; neurons; retrovesicular ganglion; and ventral nerve cord based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including Alovudine; Cry5B; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00020503 T14B4.9 Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. WB:WBGene00020504 svh-2 Enables mitogen-activated protein kinase kinase kinase binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in axon regeneration; positive regulation of MAPK cascade; and positive regulation of axon regeneration. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in distal tip cell; excretory canal; and muscle cell. Is an ortholog of human TYRO3 (TYRO3 protein tyrosine kinase). WB:WBGene00020505 T14E8.2 Predicted to enable transmembrane receptor protein tyrosine kinase activator activity. Predicted to be involved in positive regulation of MAPK cascade. Predicted to be located in terminal bouton. WB:WBGene00020506 dop-3 Enables dopamine neurotransmitter receptor activity, coupled via Gi/Go. Involved in several processes, including adenylate cyclase-inhibiting dopamine receptor signaling pathway; male mating behavior; and response to odorant. Predicted to be located in postsynaptic membrane and synaptic vesicle membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; end stage renal disease; essential tremor 1; and type 2 diabetes mellitus. Is an ortholog of human DRD3 (dopamine receptor D3). WB:WBGene00020507 vha-15 Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Is an ortholog of human ATP6V1H (ATPase H+ transporting V1 subunit H). WB:WBGene00020508 T14F9.2 Enriched in several structures, including ABplapaaaa; MSaaaaapa; PLM; ciliated neurons; and male distal tip cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Alovudine; Zidovudine; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020509 hex-1 Enables beta-N-acetylhexosaminidase activity. Involved in carbohydrate metabolic process. Predicted to be located in lysosome and membrane. Expressed in coelomocyte and pharyngeal neurons. Human ortholog(s) of this gene implicated in Sandhoff disease; Tay-Sachs disease; and spinal muscular atrophy. Is an ortholog of human HEXA (hexosaminidase subunit alpha) and HEXB (hexosaminidase subunit beta). WB:WBGene00020510 T14G11.1 Predicted to be located in membrane. WB:WBGene00020511 immt-1 Involved in cristae formation; mitochondrion morphogenesis; and response to reactive oxygen species. Located in mitochondrial inner membrane. Part of mitochondrial proton-transporting ATP synthase complex. Is an ortholog of human IMMT (inner membrane mitochondrial protein). WB:WBGene00020512 T14G12.1 No description available WB:WBGene00020514 T14G12.5 No description available WB:WBGene00020515 T14G12.6 Enriched in AVE based on tiling array studies. Is affected by several genes including daf-12; sir-2.1; and aak-2 based on microarray; tiling array; and RNA-seq studies. Is affected by Ag nanoparticles based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00020516 T15B7.1 Predicted to be located in collagen-containing extracellular matrix and extracellular space. Is an ortholog of several human genes including FCN1 (ficolin 1); FCN2 (ficolin 2); and MFAP4 (microfibril associated protein 4). WB:WBGene00020517 hpo-8 Predicted to enable 3-hydroxyacyl-CoA dehydratase activity. Predicted to be involved in fatty acid elongation; sphingolipid biosynthetic process; and very long-chain fatty acid biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital myopathy. Is an ortholog of human HACD2 (3-hydroxyacyl-CoA dehydratase 2). WB:WBGene00020520 T15B7.8 Predicted to be located in membrane. WB:WBGene00020522 T15B7.10 Enriched in ASER based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00020523 dmsr-14 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00020524 dmsr-13 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00020525 dmsr-15 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00020526 T15B7.14 Predicted to be located in membrane. WB:WBGene00020527 T15B7.15 Expressed in intestinal cell; neurons; somatic gonad; and spermatheca. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020528 lgc-54 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in AVEL; AVER; RMHL; and RMHR. WB:WBGene00020530 T15B12.1 Located in mitochondrion. Is an ortholog of human SMTNL2 (smoothelin like 2). WB:WBGene00020531 T15B12.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00020532 math-42 Expressed in intestine. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00020533 T16A1.2 Predicted to be located in membrane. WB:WBGene00020534 fbxc-49 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercuric chloride; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF3557. WB:WBGene00020535 T16A1.4 Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020536 T16A1.5 Is affected by several genes including daf-2; fzo-1; and tdp-1 based on RNA-seq and microarray studies. Is affected by Tunicamycin and paraquat based on microarray and RNA-seq studies. WB:WBGene00020537 fbxb-37 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; rotenone; and bisphenol A based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00020538 T16A1.9 No description available WB:WBGene00020539 T16D1.1 Enriched in male based on RNA-seq studies. Is affected by several genes including age-1; sir-2.1; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by Tunicamycin; Doxycycline; and paraquat based on microarray and RNA-seq studies. WB:WBGene00020540 pals-25 Expressed widely. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020541 fbxb-81 Enriched in several structures, including ABplpaaaap; ABplpppaapa; ABprpppaapa; rect_D; and terminal bulb based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00020542 fbxb-82 Enriched in IL socket cell; NSM; and tail precursor cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00020543 fbxb-83 Enriched in AIZL; AIZR; and BAG based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Mercuric Chloride; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00020544 fbxb-84 Enriched in body wall muscle cell and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00020545 adbp-2 Is affected by several genes including clk-1; mex-3; and nhr-25 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00020546 zig-13 Predicted to be located in membrane. WB:WBGene00020547 srz-7 Enriched in neurons based on microarray studies. Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Acrylamide; Chlorpyrifos; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00020548 T17A3.12 Enriched in PVPL; PVPR; and cephalic sheath cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00020549 nmt-1 Predicted to enable glycylpeptide N-tetradecanoyltransferase activity. Predicted to be located in cytoplasm. Used to study muscular disease. Is an ortholog of human NMT1 (N-myristoyltransferase 1) and NMT2 (N-myristoyltransferase 2). WB:WBGene00020550 idpp-1 Expressed in OLLL and OLLR. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00020551 T17H7.7 Enriched in several structures, including anterior hypodermis; germline precursor cell; neurons; rectal epithelial cell; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twenty-four chemicals including Ethanol; 1-methylnicotinamide; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00020553 ttc-17 Predicted to be involved in actin filament polymerization. Predicted to be located in actin cytoskeleton and cytoplasm. Expressed in head neurons; hypodermis; intestine; and vulva. Is an ortholog of human TTC17 (tetratricopeptide repeat domain 17). WB:WBGene00020554 T19A5.3 Enriched in germline precursor cell; hypodermis; and interfacial epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-four chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020555 nhr-219 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in amphid neurons; ciliated neurons; head neurons; and sensory neurons. WB:WBGene00020556 pamn-1 Predicted to enable copper ion binding activity; peptidylamidoglycolate lyase activity; and peptidylglycine monooxygenase activity. Predicted to be involved in peptide metabolic process. Predicted to be located in extracellular region. Expressed in head ganglion and tail ganglion. Human ortholog(s) of this gene implicated in prostate adenocarcinoma. Is an ortholog of human PAM (peptidylglycine alpha-amidating monooxygenase). WB:WBGene00020557 aprt-1 Predicted to enable AMP binding activity; adenine binding activity; and adenine phosphoribosyltransferase activity. Predicted to be involved in AMP salvage and adenine salvage. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in adenine phosphoribosyltransferase deficiency. Is an ortholog of human APRT (adenine phosphoribosyltransferase). WB:WBGene00020558 T19B4.5 Enriched in several structures, including ABalapaaaa; ABalappapa; ABalppappa; ABaraappaa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; sir-2.1; and npr-1 based on RNA-seq; proteomic; and microarray studies. Is affected by ten chemicals including hydrogen sulfide; rotenone; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00020559 best-17 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). WB:WBGene00020560 T19C3.2 Enriched in several structures, including NSM; germline precursor cell; interfacial epithelial cell; rectal gland cell; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including hydrogen sulfide; Nitric Oxide; and methylmercury hydroxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Uncharacterized protein T19C3.2-like. WB:WBGene00020561 T19C3.3 Enriched in hypodermis and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and sek-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including Ethanol; 1-methylnicotinamide; and nicotinic acid based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020562 T19C3.4 Predicted to enable microtubule binding activity. Predicted to be involved in endoplasmic reticulum tubular network organization. Predicted to be located in cytoplasmic microtubule; endoplasmic reticulum membrane; and endoplasmic reticulum tubular network. Human ortholog(s) of this gene implicated in distal hereditary motor neuronopathy type 5B; hereditary spastic paraplegia 31; and hereditary spastic paraplegia 72. Is an ortholog of human REEP1 (receptor accessory protein 1) and REEP4 (receptor accessory protein 4). WB:WBGene00020563 T19C3.5 Predicted to enable lipid binding activity. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in Crohn's disease; atherosclerosis; and severe acute respiratory syndrome. Is an ortholog of several human genes including BPI (bactericidal permeability increasing protein); LBP (lipopolysaccharide binding protein); and PLTP (phospholipid transfer protein). WB:WBGene00020564 T19C3.6 Enriched in NSM; XXXL; and XXXR based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00020565 T19C3.7 Enriched in XXXL and XXXR based on single-cell RNA-seq studies. Is affected by several genes including eat-2; mex-1; and dpy-21 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including aldicarb; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00020566 ttr-7 Predicted to be located in cell surface and extracellular region. WB:WBGene00020567 adt-3 Predicted to enable metalloendopeptidase activity. Predicted to be involved in extracellular matrix organization. Predicted to be located in extracellular matrix. WB:WBGene00020568 T19D2.3 Predicted to be located in membrane. WB:WBGene00020569 lgc-32 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00020571 lpr-7 Predicted to be located in membrane. WB:WBGene00020572 rund-1 Enables small GTPase binding activity. Involved in several processes, including dense core granule maturation; positive regulation of behavior; and regulation of transport. Located in several cellular components, including Golgi trans cisterna; neuronal cell body; and perinuclear region of cytoplasm. Expressed in uterus. Is an ortholog of human RUNDC1 (RUN domain containing 1). WB:WBGene00020573 T19D7.5 Predicted to be located in membrane. WB:WBGene00020574 T19D7.6 Enriched in ASER; OLL; PVD; dopaminergic neurons; and intestine based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by eleven chemicals including diallyl trisulfide; levamisole; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily and Leucine-rich melanocyte differentiation-associated protein. WB:WBGene00020575 T19D7.7 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Predicted to be located in membrane. Is an ortholog of human PLB1 (phospholipase B1). WB:WBGene00020576 T19D12.1 Predicted to be located in membrane. WB:WBGene00020577 T19D12.2 Enriched in amphid sensillum; head mesodermal cell; intestine; and mechanosensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; levamisole; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: von Willebrand factor A-like domain superfamily. WB:WBGene00020578 T19D12.3 Enriched in CEP socket cell; GABAergic neurons; excretory cell; and intestine based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by seventeen chemicals including methylmercuric chloride; Mercuric Chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00020579 T19D12.4 Involved in defense response to Gram-negative bacterium and innate immune response. Located in membrane raft. WB:WBGene00020580 T19D12.5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00020581 T19D12.6 Enriched in several structures, including distal tip cell; head ganglion; interfacial epithelial cell; neurons; and rectum based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Laminin G domain and Concanavalin A-like lectin/glucanase domain superfamily. Is an ortholog of human EGFLAM (EGF like, fibronectin type III and laminin G domains). WB:WBGene00020582 oig-8 Predicted to be located in membrane. Expressed in sensory neurons. WB:WBGene00020583 T19D12.9 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00020584 T19D12.10 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00020585 clec-178 Predicted to enable signaling receptor activity. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and liver cirrhosis. Is an ortholog of human REG3A (regenerating family member 3 alpha) and REG4 (regenerating family member 4). WB:WBGene00020586 frpr-18 Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway; positive regulation of protein secretion; and sleep. Located in plasma membrane. Expressed in enteric muscle and neurons. WB:WBGene00020587 ugt-9 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Expressed in pharyngeal cell. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00020588 T19H12.2 Predicted to enable histone binding activity. Predicted to be located in nucleus. Expressed in germ line. Is an ortholog of human ANP32B (acidic nuclear phosphoprotein 32 family member B); ANP32CP (acidic nuclear phosphoprotein 32 family member C, pseudogene); and ANP32E (acidic nuclear phosphoprotein 32 family member E). WB:WBGene00020589 T19H12.3 Enriched in AMshL; AMshR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020590 T19H12.6 Predicted to enable glutathione hydrolase activity. Predicted to be involved in glutathione catabolic process. Predicted to be located in plasma membrane. WB:WBGene00020591 nhr-220 Is affected by several genes including hsf-1; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00020592 ugt-12 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00020593 ugt-11 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT8 (UDP glycosyltransferase 8). WB:WBGene00020594 ugt-10 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00020595 T20B5.2 Enriched in DVA; anterior arcade cell; pharyngeal cell; pharyngeal-intestinal valve; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Tunicamycin; Zidovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020596 oga-1 Enables hexosaminidase activity and protein serine/threonine phosphatase activity. Involved in several processes, including glycogen metabolic process; lipid storage; and negative regulation of protein glycosylation. Expressed in body wall musculature; coelomocyte; nerve ring; pharyngeal muscle cell; and rectal muscle. Used to study type 2 diabetes mellitus. Is an ortholog of human OGA (O-GlcNAcase). WB:WBGene00020598 T20B6.2 Enriched in excretory duct; excretory pore; neurons; sensory neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00020599 idpa-1 Enriched in AFD; MSaapapa; MSpapapa; pharyngeal muscle cell; and phasmid neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including D-glucose; Cry5B; and stavudine based on RNA-seq and microarray studies. WB:WBGene00020600 trd-1 Predicted to be involved in cell differentiation. Predicted to be located in cytoplasm. Expressed in gonad; gonadal primordium; seam cell; and vulval precursor cell. Is an ortholog of human TTC27 (tetratricopeptide repeat domain 27). WB:WBGene00020601 T20B12.3 Predicted to be involved in ribosome biogenesis. Predicted to be located in nucleolus. Predicted to be part of Noc4p-Nop14p complex and small-subunit processome. Is an ortholog of human NOC4L (nucleolar complex associated 4 homolog). WB:WBGene00020602 T20B12.4 Enriched in Z1.p; Z4.a; male distal tip cell; neurons; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: F-box protein she-1-like. WB:WBGene00020603 T20B12.5 Enriched in neurons and retrovesicular ganglion based on microarray studies. Is affected by several genes including eat-2; sir-2.1; and set-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020604 T20B12.7 Predicted to enable electron transfer activity; iron-sulfur cluster binding activity; and metal ion binding activity. Predicted to be involved in iron-sulfur cluster assembly. Predicted to be located in cytoplasm. Is an ortholog of human CIAPIN1 (cytokine induced apoptosis inhibitor 1). WB:WBGene00020605 lgc-50 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00020607 srab-20 Predicted to be located in membrane. Expressed in ganglia and head mesodermal cell. WB:WBGene00020608 srab-22 Predicted to be located in membrane. WB:WBGene00020609 T20D4.3 Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Predicted to be involved in glycoprotein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Predicted to be located in cytosol and nucleus. WB:WBGene00020611 txt-11 Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Predicted to be involved in glycoprotein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Predicted to be located in cytosol and nucleus. WB:WBGene00020612 arrd-22 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. Is an ortholog of human ARRDC1 (arrestin domain containing 1) and ARRDC2 (arrestin domain containing 2). WB:WBGene00020613 T20D4.7 Involved in PERK-mediated unfolded protein response. Is an ortholog of human NXNL2 (nucleoredoxin like 2). WB:WBGene00020614 T20D4.8 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including sir-2.1; aak-2; and dpy-21 based on microarray and RNA-seq studies. Is affected by dibromoacetic acid; dafa#1; and Sirolimus based on microarray studies. WB:WBGene00020615 T20D4.9 Enriched in NSM and body wall muscle cell based on tiling array studies. Is affected by several genes including rrf-3; clk-1; and aak-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00020616 T20D4.10 Enriched in OLL; PVD; body wall muscle cell; and muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seventeen chemicals including hydrogen sulfide; 1-methylnicotinamide; and nicotinic acid based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00020617 T20D4.11 Enriched in OLL; PVD; body wall muscle cell; and muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00020618 T20D4.12 Enriched in cephalic sheath cell; dopaminergic neurons; hypodermis; mechanosensory neurons; and muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; Ethanol; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00020619 T20D4.13 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020620 T20D4.15 Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including multi-walled carbon nanotube; glycine; and CGP37157 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00020622 T20D4.17 Enriched in AFD and body wall muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; cadmium; and Chlorpyrifos based on RNA-seq and microarray studies. WB:WBGene00020623 srab-21 Predicted to be located in membrane. WB:WBGene00020624 T20D4.19 Enriched in ABarpaaa and tail precursor cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including bisphenol S; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00020625 mrrf-1 Predicted to enable ribosomal large subunit binding activity. Predicted to be involved in translation. Predicted to be located in mitochondrion. Is an ortholog of human MRRF (mitochondrial ribosome recycling factor). WB:WBGene00020626 T20F5.4 Enriched in several structures, including germline precursor cell; hyp3; interfacial epithelial cell; intestine; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-five chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00020627 T20F5.5 Predicted to be located in membrane. WB:WBGene00020628 T20F5.6 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. WB:WBGene00020629 T20F5.7 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. WB:WBGene00020630 T20F7.1 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by ten chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type and Phosphorylation site. WB:WBGene00020631 T20F7.3 Predicted to enable inositol hexakisphosphate kinase activity. Predicted to be involved in inositol phosphate biosynthetic process and phosphatidylinositol phosphate biosynthetic process. Predicted to be located in cytoplasm and nucleus. WB:WBGene00020632 T20F7.5 Enriched in coelomocyte; head mesodermal cell; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including glp-1; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020633 aakg-2 Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleotide-activated protein kinase complex. Human ortholog(s) of this gene implicated in Wolff-Parkinson-White syndrome; hypertrophic cardiomyopathy 6; and lethal congenital glycogen storage disease of heart. Is an ortholog of human PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1); PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2); and PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3). WB:WBGene00020634 acs-9 Predicted to enable CoA-ligase activity. WB:WBGene00020635 ztf-31 Expressed in head neurons. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00020636 ndus-8 Predicted to enable 4 iron, 4 sulfur cluster binding activity; NADH dehydrogenase (ubiquinone) activity; and metal ion binding activity. Predicted to contribute to NADH dehydrogenase activity. Involved in mitochondrial electron transport, NADH to ubiquinone and response to xenobiotic stimulus. Located in mitochondrion. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 2. Is an ortholog of human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8). WB:WBGene00020637 fbxa-7 Enriched in intestine based on RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Mercuric Chloride; allantoin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00020638 fbxa-43 Enriched in command interneuron and rectal epithelial cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including age-1; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00020639 fbxa-71 Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Psoralens; Rifampin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00020640 fbxa-73 Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including stavudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00020641 fbxa-68 Is affected by several genes including clk-1; lin-35; and lin-15B based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00020642 T20H9.6 Enriched in neurons based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00020644 T20H12.2 No description available WB:WBGene00020645 T21D9.2 Predicted to be located in membrane. WB:WBGene00020646 zmp-6 Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to be located in extracellular matrix. Expressed in anchor cell. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); reproductive organ cancer (multiple); and tooth disease (multiple). Is an ortholog of human MMP26 (matrix metallopeptidase 26). WB:WBGene00020647 pqbp-1.1 Predicted to enable ribonucleoprotein complex binding activity. Involved in triglyceride metabolic process. Located in nuclear body. Expressed in gonad. Used to study Renpenning syndrome. Human ortholog(s) of this gene implicated in Renpenning syndrome. Is an ortholog of human PQBP1 (polyglutamine binding protein 1). WB:WBGene00020648 T21D12.7 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00020649 sma-10 Enables type I transforming growth factor beta receptor binding activity and type II transforming growth factor beta receptor binding activity. Involved in several processes, including positive regulation of transforming growth factor beta receptor signaling pathway; regulation of mesodermal cell fate specification; and transforming growth factor beta receptor signaling pathway. Located in plasma membrane. Human ortholog(s) of this gene implicated in urofacial syndrome. Is an ortholog of human LRIG2 (leucine rich repeats and immunoglobulin like domains 2). WB:WBGene00020650 T21D12.11 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00020651 T21D12.12 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00020652 egg-4 Enables protein kinase binding activity and protein kinase inhibitor activity. Involved in cortical actin cytoskeleton organization; female gamete generation; and positive regulation of protein localization to cell cortex. Located in cell cortex and nucleus. Expressed in germ line and oocyte. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Is an ortholog of human PTPRG (protein tyrosine phosphatase receptor type G) and PTPRZ1 (protein tyrosine phosphatase receptor type Z1). WB:WBGene00020653 T21E3.2 Enriched in several structures, including ABplapaaaa; ABprapaaaa; arcade cell; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00020655 T21E12.3 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00020656 T21E12.5 Predicted to be located in membrane. WB:WBGene00020657 lgc-53 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in neurons. WB:WBGene00020658 argn-1 Predicted to enable arginase activity and manganese ion binding activity. Involved in innate immune response. Predicted to be located in cytosol. Expressed in hypodermal cell. Used to study hyperargininemia. Human ortholog(s) of this gene implicated in several diseases, including colitis; hepatocellular carcinoma; and hyperargininemia. Is an ortholog of human ARG1 (arginase 1) and ARG2 (arginase 2). WB:WBGene00020659 T21G5.1 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00020660 T21G5.2 Predicted to be located in membrane. WB:WBGene00020661 smz-2 Involved in male meiosis chromosome segregation. Part of chromatin. Expressed in sperm. WB:WBGene00020662 T21H3.1 Predicted to be involved in lipid metabolic process. WB:WBGene00020663 cutl-22 Predicted to be located in membrane. WB:WBGene00020664 T21H3.5 Predicted to be located in membrane. WB:WBGene00020665 T22B2.1 Predicted to enable metal ion binding activity. Predicted to be involved in innate immune response. WB:WBGene00020666 T22B2.2 Predicted to be located in membrane. WB:WBGene00020667 T22B2.3 Enriched in Z1.p; Z4.a; male distal tip cell; sensory neurons; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including eat-2; elt-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020669 T22B2.5 Predicted to be located in membrane. WB:WBGene00020670 idpp-9 Enriched in DA neuron and VA neuron based on microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; Mercuric Chloride; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00020672 T22B7.3 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and carbon dioxide sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including Heme; Ethanol; and mianserin based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in coronary artery disease and hypertension. Human DDAH1 enables dimethylargininase activity. Is predicted to encode a protein with the following domain: N,N dimethylarginine dimethylhydrolase, eukaryotic. Is an ortholog of human DDAH1 (dimethylarginine dimethylaminohydrolase 1). WB:WBGene00020673 T22B7.4 Predicted to enable methylated histone binding activity. Predicted to be located in nucleus. Predicted to be part of SAGA complex. Human ortholog(s) of this gene implicated in diabetic retinopathy. Is an ortholog of human SGF29 (SAGA complex associated factor 29). WB:WBGene00020674 T22B7.7 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human ACOT9 (acyl-CoA thioesterase 9). WB:WBGene00020675 spe-51 Enriched in AIN; MC neuron; somatic gonad precursor; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including manganese chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020678 kin-36 Predicted to enable protein kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. Expressed in pharyngeal gland cell; pharyngeal neurons; and vulval cell. WB:WBGene00020679 ogdh-1 Predicted to enable oxoglutarate dehydrogenase (succinyl-transferring) activity. Involved in protein folding. Located in mitochondrion. Expressed in head and tail. Human ortholog(s) of this gene implicated in oxoglutarate dehydrogenase deficiency. Is an ortholog of human OGDH (oxoglutarate dehydrogenase). WB:WBGene00020680 T22D1.1 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00020682 T22D1.3 Predicted to enable IMP dehydrogenase activity. Predicted to be involved in GTP biosynthetic process. Predicted to be located in cytoplasm. Expressed in head and tail. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 11 and retinitis pigmentosa 10. Is an ortholog of human IMPDH1 (inosine monophosphate dehydrogenase 1). WB:WBGene00020683 ribo-1 Predicted to be involved in protein glycosylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Is an ortholog of human RPN1 (ribophorin I). WB:WBGene00020684 T22D1.5 Predicted to enable protein phosphatase regulator activity. Predicted to be part of protein phosphatase type 2A complex. WB:WBGene00020686 T22D1.8 Predicted to be located in membrane. WB:WBGene00020687 ruvb-2 Predicted to enable DNA helicase activity. Predicted to be involved in box C/D snoRNP assembly; chromatin remodeling; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Expressed in gonad. Is an ortholog of human RUVBL2 (RuvB like AAA ATPase 2). WB:WBGene00020688 cest-6 Predicted to be located in membrane. WB:WBGene00020689 npr-12 Predicted to enable neuropeptide Y receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in FLPL; FLPR; PVDL; and PVDR. Human ortholog(s) of this gene implicated in peripheral artery disease and temporal lobe epilepsy. Is an ortholog of human NPY1R (neuropeptide Y receptor Y1); NPY4R (neuropeptide Y receptor Y4); and NPY4R2 (neuropeptide Y receptor Y4-2). WB:WBGene00020690 T22E5.1 Enriched in body wall musculature; intestine; neurons; retrovesicular ganglion; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and isp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Mercuric Chloride; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00020691 igdb-3 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Fibronectin type III superfamily; Immunoglobulin-like fold; Domain of unknown function DB; DB module; Fibronectin type III; Fibronectin type III domain; and Immunoglobulin-like domain superfamily. WB:WBGene00020692 T22E5.6 Predicted to be located in plasma membrane. Expressed in pharynx. WB:WBGene00020693 lron-8 Predicted to be located in extracellular matrix and extracellular space. Expressed in body wall musculature; head muscle; pharynx; and rectal gland cell. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive intellectual developmental disorder 64; congenital stationary night blindness 1A; and stomach cancer. Is an ortholog of several human genes including LRRN1 (leucine rich repeat neuronal 1); LRRN2 (leucine rich repeat neuronal 2); and LRRN3 (leucine rich repeat neuronal 3). WB:WBGene00020694 dhhc-11 Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Expressed in head neurons and spermathecal-uterine junction. Is an ortholog of human ZDHHC11 (zinc finger DHHC-type containing 11). WB:WBGene00020695 T22F3.2 Predicted to enable cysteine-type deubiquitinase activity. WB:WBGene00020696 pygl-1 Predicted to enable glycogen phosphorylase activity and pyridoxal phosphate binding activity. Predicted to be involved in glycogen catabolic process. Predicted to be located in cytoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in glycogen storage disease V; glycogen storage disease VI; and lactic acidosis. Is an ortholog of human PYGM (glycogen phosphorylase, muscle associated). WB:WBGene00020697 T22F3.7 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00020698 T22F3.8 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00020699 T22F3.10 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00020700 T22F3.11 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00020701 T22F7.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC22A1 (solute carrier family 22 member 1). WB:WBGene00020702 T22F7.3 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00020703 T22F7.4 Enriched in coelomocyte; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including 1-methylnicotinamide; nicotinic acid; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterized protein F10E9.3-like and Phosphorylation site. WB:WBGene00020705 T22H9.1 Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of 90S preribosome. Is an ortholog of human RRP36 (ribosomal RNA processing 36). WB:WBGene00020706 atg-9 Involved in regulation of presynapse assembly. Located in cytoplasm and presynapse. Expressed in several structures, including AIY; hypodermis; nerve ring; neuronal sheath cell; and spermatheca. Is an ortholog of human ATG9A (autophagy related 9A). WB:WBGene00020707 wago-10 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. WB:WBGene00020708 dmd-8 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to be located in nucleus. Expressed in amphid neurons. Is an ortholog of human DMRTB1 (DMRT like family B with proline rich C-terminal 1). WB:WBGene00020709 T23B3.1 Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and sek-1 based on RNA-seq; microarray; and proteomic studies. Is affected by Zidovudine; paraquat; and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00020710 T23B3.2 Predicted to be located in membrane. WB:WBGene00020711 rmd-5 Enriched in ASK; OLQ; and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube; metformin; and cadmium based on RNA-seq studies. WB:WBGene00020712 ckr-1 Predicted to enable neuropeptide receptor activity. Involved in determination of adult lifespan. Predicted to be located in plasma membrane. Expressed in intestine; nerve ring; and neurons. Human ortholog(s) of this gene implicated in cholelithiasis; obesity; and pancreatic ductal carcinoma. Is an ortholog of human CCKAR (cholecystokinin A receptor). WB:WBGene00020713 T23B3.5 Enriched in AFD; germ line; intestine; sperm; and in male based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-nine chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00020714 T23B3.6 Predicted to be located in membrane. WB:WBGene00020715 nspd-4 Enriched in arcade cell; intestine; pharyngeal-intestinal valve cell; sperm; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-nine chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Caenorhabditis elegans protein of unknown function (DUF780) and Protein of unknown function DUF780, Caenorhabditis species. WB:WBGene00020716 phf-30 Predicted to enable metal ion binding activity. Predicted to be located in nucleus. Is an ortholog of human INTS12 (integrator complex subunit 12). WB:WBGene00020717 mrpl-4 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human MRPL4 (mitochondrial ribosomal protein L4). WB:WBGene00020718 mrps-2 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 36. Is an ortholog of human MRPS2 (mitochondrial ribosomal protein S2). WB:WBGene00020719 natc-1 Predicted to contribute to peptide alpha-N-acetyltransferase activity. Involved in several processes, including determination of adult lifespan; response to paraquat; and stress response to metal ion. Located in cytoplasm. Is an ortholog of human NAA35 (N-alpha-acetyltransferase 35, NatC auxiliary subunit). WB:WBGene00020720 T23B12.5 Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00020721 T23B12.6 Predicted to be involved in protein homooligomerization. Is an ortholog of human KCTD3 (potassium channel tetramerization domain containing 3) and SHKBP1 (SH3KBP1 binding protein 1). WB:WBGene00020722 gplb-1 Predicted to enable hormone activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasm and extracellular space. WB:WBGene00020723 T23B12.9 No description available WB:WBGene00020724 T23B12.10 No description available WB:WBGene00020725 cnp-3 Predicted to be located in nucleus. Expressed in hypodermis; intestine; spermatheca; and uterus. WB:WBGene00020726 T23C6.4 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapapapa; ABalapappaa; and neurons based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020727 npr-21 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. Expressed in head neurons; intestine; tail neurons; and ventral nerve cord. WB:WBGene00020728 T23E1.1 Predicted to be located in membrane. WB:WBGene00020729 T23E1.2 Enriched in germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; mianserin; and stavudine based on RNA-seq studies. WB:WBGene00020730 T23E1.3 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by D-glucose; paraquat; and Colistin based on RNA-seq and microarray studies. WB:WBGene00020731 T23E7.1 No description available WB:WBGene00020732 T23E7.2 Enriched in AFD; germ line; head mesodermal cell; and muscle cell based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-two chemicals including 1-methylnicotinamide; nicotinic acid; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020733 T23E7.3 No description available WB:WBGene00020735 T23F2.2 Enriched in head mesodermal cell; muscle cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including stavudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020736 T23F2.3 Predicted to be located in membrane. WB:WBGene00020737 T23F2.4 Predicted to be located in membrane. WB:WBGene00020738 T23F2.5 Predicted to be located in membrane. WB:WBGene00020739 T23F4.1 Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Humic Substances; and dafa#1 based on RNA-seq and microarray studies. WB:WBGene00020740 T23F4.2 Enriched in amphid socket cell; head mesodermal cell; intestine; mechanosensory neurons; and rectal gland cell based on tiling array; proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; Rifampin; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020741 dlhd-1 Predicted to enable hydrolase activity. WB:WBGene00020742 T23H2.3 Predicted to enable ATP-dependent activity, acting on DNA. Predicted to be involved in DNA repair. Predicted to be located in nucleus. Is an ortholog of human TTF2 (transcription termination factor 2). WB:WBGene00020743 mam-8 Predicted to be located in membrane. Expressed in head neurons. WB:WBGene00020744 T24A6.1 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in mitotic cell cycle phase transition. Predicted to be located in cytoplasm and nucleus. Predicted to be part of cyclin A2-CDK2 complex. WB:WBGene00020746 srbc-66 Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and dauer larval development. Located in non-motile cilium and periciliary membrane compartment. Expressed in ASKL and ASKR. WB:WBGene00020747 T24A6.7 Enriched in amphid sheath cell; body wall muscle cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and npr-1 based on proteomic; microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; procyanidin; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: YbiA-like superfamily; NADAR domain; and NADAR. WB:WBGene00020748 nhr-221 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00020749 srbc-67 Predicted to be located in membrane. WB:WBGene00020750 nhr-222 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00020751 srbc-69 No description available WB:WBGene00020752 srbc-68 Predicted to be located in membrane. WB:WBGene00020753 T24A6.16 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00020754 T24A6.17 Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00020755 grl-31 Expressed in vulF. Is predicted to encode a protein with the following domain: Ground-like domain. WB:WBGene00020756 T24A6.20 Enriched in amphid sheath cell; coelomocyte; excretory cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; proteomic; and RNA-seq studies. Is affected by nine chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Acyl-CoA N-acyltransferase; YitH/HolE, acetyltransferase (GNAT) domain; and Acetyltransferase (GNAT) domain. WB:WBGene00020757 ucr-2.3 Predicted to enable metalloendopeptidase activity. Involved in protein folding. Predicted to be located in mitochondrial matrix. Expressed in neurons and pharyngeal gland cell. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 5. Is an ortholog of human UQCRC2 (ubiquinol-cytochrome c reductase core protein 2). WB:WBGene00020758 T24C4.2 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalpapaap; AVK; and amphid neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; rotenone; and bisphenol S based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF5575. WB:WBGene00020759 T24C4.3 Enriched in neurons and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; alg-1; and mex-3 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; tryptophan; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00020760 T24C4.4 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00020761 T24C4.5 Predicted to enable DNA primase activity and metal ion binding activity. Predicted to be involved in DNA replication, synthesis of RNA primer. Predicted to be part of alpha DNA polymerase:primase complex. Is an ortholog of human PRIM1 (DNA primase subunit 1). WB:WBGene00020762 zer-1 Part of Cul2-RING ubiquitin ligase complex. Is an ortholog of human ZER1 (zyg-11 related cell cycle regulator). WB:WBGene00020763 ztf-18 Predicted to enable nucleic acid binding activity. Expressed in body wall musculature; head neurons; tail neurons; and ventral nerve cord. WB:WBGene00020764 T24C12.1 Predicted to be located in membrane. WB:WBGene00020765 T24C12.3 Predicted to enable several functions, including kinase activity; metal ion binding activity; and pseudouridylate synthase activity. Predicted to be involved in phosphorylation and pseudouridine synthesis. WB:WBGene00020766 T24C12.4 Predicted to be located in membrane. WB:WBGene00020767 lgc-40 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00020769 T24D8.6 Enriched in mc2DL; mc2DR; mc2V; pm7; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; eri-1; and bar-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00020770 eat-17 Predicted to enable GTPase activator activity. Involved in positive regulation of feeding behavior and regulation of presynaptic dense core granule exocytosis. Located in cholinergic synapse. Expressed in intestine; pharyngeal muscle cell; and vulva. Is an ortholog of human EVI5 (ecotropic viral integration site 5) and EVI5L (ecotropic viral integration site 5 like). WB:WBGene00020771 T24E12.1 Enriched in several structures, including ABplaapappp; ABplpppppp; ABpraapappp; ABprpppppp; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00020772 T24E12.2 Enriched in ABplaapappp; ABpraapappp; intestine; sensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00020773 T24E12.3 Enriched in several structures, including Z1.p; Z4.a; male distal tip cell; sensory neurons; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including elt-2; pgl-1; and glh-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00020774 rcd-1 Predicted to be located in membrane. WB:WBGene00020775 T24E12.6 Enriched in amphid sheath cell and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including clk-1; ubc-9; and hda-2 based on microarray and RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00020777 T24E12.10 Enriched in several structures, including Z1.p; head ganglion; male distal tip cell; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; metformin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00020778 T24E12.11 Enriched in several structures, including ABplaapappp; ASI; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020779 T24G10.2 Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00020780 T24H5.1 No description available WB:WBGene00020781 T24H7.2 Predicted to enable adenyl-nucleotide exchange factor activity. Involved in IRE1-mediated unfolded protein response. Predicted to be part of endoplasmic reticulum chaperone complex. Human ortholog(s) of this gene implicated in immunodeficiency 59. Is an ortholog of human HYOU1 (hypoxia up-regulated 1). WB:WBGene00020782 lelo-1 Predicted to enable kinase regulator activity and protein kinase A binding activity. Predicted to be involved in regulation of canonical Wnt signaling pathway. Predicted to be located in cytoplasm. Is an ortholog of human GSKIP (GSK3B interacting protein). WB:WBGene00020783 blos-4 Involved in endosomal transport. Predicted to be part of BLOC-1 complex. WB:WBGene00020784 tat-4 Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Involved in sterol metabolic process. Predicted to be located in plasma membrane. Expressed in hermaphrodite gonad; intestine; pharyngeal-intestinal valve; and rectal gland cell. Is an ortholog of human ATP10A (ATPase phospholipid transporting 10A (putative)); ATP10B (ATPase phospholipid transporting 10B (putative)); and ATP10D (ATPase phospholipid transporting 10D (putative)). WB:WBGene00020785 T25B2.1 Enriched in several structures, including ABalpapppa; ABalpppappp; ABalppppaa; excretory system; and marginal cell based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; clk-1; and bar-1 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00020786 T25B2.2 Enriched in RIP; pharyngeal cell; pharyngeal-intestinal valve; and spermatheca based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by seventeen chemicals including aldicarb; Ethanol; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020787 T25B6.1 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by Diazinon and Sirolimus based on microarray studies. WB:WBGene00020788 nep-22 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Located in membrane raft. WB:WBGene00020789 T25B6.3 Enriched in ASIL; ASIR; HSN; coelomocyte; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020790 T25B6.4 Enriched in coelomocyte and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and unc-30 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Rifampin; Sirolimus; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020791 T25B6.5 Enriched in GABAergic neurons; PVT; body wall musculature; neurons; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including elt-2; sir-2.1; and npr-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Tunicamycin; Sodium Chloride; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00020792 T25B6.6 Enriched in intestine and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; elt-2; and sir-2.1 based on microarray; RNA-seq; and tiling array studies. Is affected by seven chemicals including Tunicamycin; Sodium Chloride; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00020793 T25D1.1 Enriched in AFD and body wall muscle cell based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including eat-2; spr-5; and cyc-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020794 T25D1.2 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by cadmium based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1258) and Protein of unknown function DUF1258. WB:WBGene00020795 T25D1.3 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including eat-2; hrde-1; and set-2 based on tiling array; microarray; and RNA-seq studies. Is affected by allantoin based on microarray studies. WB:WBGene00020796 mrpl-28 Predicted to be a structural constituent of ribosome. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Expressed in hypodermis and pharynx. Is an ortholog of human MRPL28 (mitochondrial ribosomal protein L28). WB:WBGene00020797 T25D3.3 Predicted to be involved in cysteine biosynthetic process. Predicted to be located in cytoplasm. WB:WBGene00020798 T25D3.4 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human MFSD14A (major facilitator superfamily domain containing 14A) and MFSD14B (major facilitator superfamily domain containing 14B). WB:WBGene00020799 T25D10.1 Involved in innate immune response. Predicted to be located in membrane. WB:WBGene00020800 zig-10 Predicted to be involved in synapse organization. Predicted to be located in neuron projection membrane. Expressed in cholinergic neurons; head neurons; hypodermis; and seam cell. Human ortholog(s) of this gene implicated in several diseases, including basal ganglia calcification; hypertension; and systemic scleroderma. Is an ortholog of human F11R (F11 receptor); JAM2 (junctional adhesion molecule 2); and JAM3 (junctional adhesion molecule 3). WB:WBGene00020801 T25D10.4 Enriched in several structures, including excretory gland cell; head mesodermal cell; interfacial epithelial cell; neurons; and terminal bulb based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00020802 btb-2 Enriched in head mesodermal cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00020803 T25E4.1 Enriched in several structures, including anterior hypodermis; arcade cell; germ line; neurons; and pharynx based on microarray; proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including methylmercury hydroxide; 1-methylnicotinamide; and Tunicamycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Family of unknown function (DUF5346) and Protein of unknown function DUF5346. WB:WBGene00020804 T25E4.2 Predicted to be located in membrane. WB:WBGene00020805 T25F10.1 Is affected by several genes including sir-2.1; sod-2; and csr-1 based on microarray and RNA-seq studies. Is affected by four chemicals including silicon dioxide nanoparticle; paraquat; and cadmium based on microarray and RNA-seq studies. WB:WBGene00020806 T25F10.3 Predicted to enable Notch binding activity. Predicted to be located in membrane. WB:WBGene00020807 T25F10.4 Predicted to enable extracellular ligand-gated monoatomic ion channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00020808 clik-1 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to be located in actin cytoskeleton. WB:WBGene00020809 T25G12.1 Enriched in intestine based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00020811 T25G12.3 Enriched in CANL; CANR; excretory cell; and seam cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020812 acdh-7 Predicted to enable medium-chain-acyl-CoA dehydrogenase activity. Predicted to be involved in medium-chain fatty acid catabolic process. Predicted to be located in mitochondrion. Expressed in anterior gonad arm. Human ortholog(s) of this gene implicated in medium chain acyl-CoA dehydrogenase deficiency. Is an ortholog of human ACADM (acyl-CoA dehydrogenase medium chain). WB:WBGene00020813 T25G12.6 Predicted to be located in membrane. WB:WBGene00020814 T25G12.8 No description available WB:WBGene00020815 T25G12.9 No description available WB:WBGene00020817 T25G12.11 Predicted to be located in membrane. WB:WBGene00020819 T26A5.2 Enriched in germ line; germline precursor cell; head mesodermal cell; and seam cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00020820 algn-1 Predicted to enable mannosyltransferase activity. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ik. Is an ortholog of human ALG1 (ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase). WB:WBGene00020821 jhdm-1 Predicted to enable histone demethylase activity and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; lung non-small cell carcinoma; and pancreatic ductal carcinoma. Is an ortholog of human KDM2B (lysine demethylase 2B). WB:WBGene00020822 T26A5.6 Predicted to be located in cytoplasm. Is an ortholog of human AVL9 (AVL9 cell migration associated). WB:WBGene00020823 T26A5.8 Predicted to enable chromatin DNA binding activity. Predicted to be involved in DNA damage response; heterochromatin formation; and leading strand elongation. Predicted to be part of CHRAC and epsilon DNA polymerase complex. Expressed in body wall musculature; head neurons; intestine; tail neurons; and ventral nerve cord. Is an ortholog of human POLE3 (DNA polymerase epsilon 3, accessory subunit). WB:WBGene00020824 pdtf-1 Predicted to be located in membrane. WB:WBGene00020825 tmem-231 Involved in non-motile cilium assembly. Located in ciliary transition zone. Expressed in amphid neurons; ciliated neurons; inner labial neurons; outer labial neurons; and phasmid neurons. Used to study Meckel syndrome and orofaciodigital syndrome. Human ortholog(s) of this gene implicated in Joubert syndrome 20 and Meckel syndrome. Is an ortholog of human TMEM231 (transmembrane protein 231). WB:WBGene00020826 T26A8.3 Enriched in several structures, including ABalppppapa; ABarpapaapp; ABplaaaaapp; ciliated neurons; and germ line based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Transthyretin-like superfamily. WB:WBGene00020827 T26A8.4 Predicted to enable RNA binding activity and metal ion binding activity. Predicted to be involved in RNA metabolic process and negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of human ZC3H4 (zinc finger CCCH-type containing 4); ZC3H6 (zinc finger CCCH-type containing 6); and ZC3H8 (zinc finger CCCH-type containing 8). WB:WBGene00020829 T26C11.3 Enriched in NSM and body wall muscle cell based on tiling array studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by paraquat and allantoin based on RNA-seq and microarray studies. WB:WBGene00020830 T26C11.4 Enriched in germ line; neurons; and retrovesicular ganglion based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and pmk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Zidovudine; Cry5B; and Doxycycline based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020831 T26C12.1 Predicted to enable acetolactate synthase activity and flavin adenine dinucleotide binding activity. Predicted to be involved in fatty acid alpha-oxidation; isoleucine biosynthetic process; and valine biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of acetolactate synthase complex. Is an ortholog of human ILVBL (ilvB acetolactate synthase like). WB:WBGene00020832 T26C12.2 Predicted to be located in membrane. WB:WBGene00020833 T26C12.3 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in small GTPase mediated signal transduction. Predicted to be located in plasma membrane. WB:WBGene00020834 T27A1.2 Enriched in several structures, including ABalaaaala; AVK; GLR; ciliated neurons; and germ line based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00020835 T27A1.3 Predicted to be located in membrane. WB:WBGene00020836 lgc-34 Predicted to enable neurotransmitter receptor activity. Predicted to be involved in monoatomic ion transmembrane transport. Located in plasma membrane. Expressed in head and intestinal muscle. WB:WBGene00020837 slc-36.2 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in vacuolar membrane. Human ortholog(s) of this gene implicated in iminoglycinuria. Is an ortholog of several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A4 (solute carrier family 36 member 4). WB:WBGene00020838 trak-1 Predicted to enable myosin binding activity. Predicted to be involved in mitochondrion distribution; protein targeting; and vesicle transport along microtubule. Predicted to be located in cytoplasmic vesicle and mitochondrion. Expressed in several structures, including CAN; amphid neurons; hermaphrodite somatic gonadal cell; phasmid sensillum; and rectum. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 68. Is an ortholog of human TRAK1 (trafficking kinesin protein 1). WB:WBGene00020839 usp-5 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in proteolysis. Predicted to be located in cytosol and nucleus. Is an ortholog of human USP13 (ubiquitin specific peptidase 13) and USP5 (ubiquitin specific peptidase 5). WB:WBGene00020840 spch-3 Part of chromatin. Expressed in sperm. WB:WBGene00020841 T27A3.5 Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of human PTPN7 (protein tyrosine phosphatase non-receptor type 7). WB:WBGene00020842 nmrk-1 Predicted to enable molybdopterin synthase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process. Predicted to be located in cytosol. Predicted to be part of molybdopterin synthase complex. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type B. Is an ortholog of human MOCS2 (molybdenum cofactor synthesis 2). WB:WBGene00020843 nse-1 Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in double-strand break repair via homologous recombination. Predicted to be located in nucleus. Predicted to be part of Smc5-Smc6 complex. Is an ortholog of human NSMCE1 (NSE1 homolog, SMC5-SMC6 complex component). WB:WBGene00020844 T27A10.2 Enriched in neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by four chemicals including rotenone; D-glucose; and metformin based on RNA-seq studies. WB:WBGene00020845 T27A10.5 Enriched in AVK based on RNA-seq studies. Is affected by several genes including sir-2.1; mir-34; and etr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00020846 T27A10.6 Expressed in seam cell. WB:WBGene00020847 cgr-1 Located in cytoplasm. Expressed in intestine. WB:WBGene00020849 nhr-225 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00020850 nhr-226 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in intestine. WB:WBGene00020851 nhr-227 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00020852 nhr-228 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons; intestine; pharynx; and tail neurons. WB:WBGene00020853 fbxa-137 Enriched in several structures, including ABalaappppa; ABalapaappa; alimentary muscle; neurons; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00020854 nrsn-1 Predicted to be involved in nervous system development. Predicted to be located in neuron projection; neuronal cell body; and transport vesicle. WB:WBGene00020855 hpo-36 Predicted to be located in membrane. WB:WBGene00020856 srt-61 Predicted to be located in membrane. WB:WBGene00020857 srt-62 Predicted to be located in membrane. WB:WBGene00020858 mop-25.3 Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in intracellular signal transduction. WB:WBGene00020859 bath-25 Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; multi-walled carbon nanotube; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00020860 nspd-10 Enriched in amphid sheath cell; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Caenorhabditis elegans protein of unknown function (DUF780) and Protein of unknown function DUF780, Caenorhabditis species. WB:WBGene00020861 T27E4.1 Predicted to enable several functions, including SNARE binding activity; calcium ion binding activity; and phospholipid binding activity. Predicted to be involved in cellular response to calcium ion; regulation of secretion by cell; and vesicle-mediated transport. Predicted to be located in several cellular components, including axon; exocytic vesicle; and synapse. WB:WBGene00020862 fip-2 Enriched in arcade cell; neurons; and pharyngeal gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; Ethanol; and rotenone based on microarray and RNA-seq studies. WB:WBGene00020863 T27E4.5 Predicted to enable peptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00020864 oac-50 Predicted to be located in membrane. WB:WBGene00020865 T27E4.7 Enriched in several structures, including AVF; G2; W cell; intestine; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00020866 vps-24 Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Predicted to be located in multivesicular body. Predicted to be part of ESCRT III complex. Is an ortholog of human CHMP3 (charged multivesicular body protein 3) and RNF103-CHMP3 (RNF103-CHMP3 readthrough). WB:WBGene00020867 shc-2 Enriched in several structures, including ABalpapaap; excretory gland cell; g1; neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including 1-methylnicotinamide; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SH2 domain and SH2 domain superfamily. Is an ortholog of human SH2D5 (SH2 domain containing 5). WB:WBGene00020868 eif-1 Predicted to enable RNA binding activity; ribosomal small subunit binding activity; and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic 43S preinitiation complex. Expressed in head and tail. Is an ortholog of human EIF1B (eukaryotic translation initiation factor 1B). WB:WBGene00020869 T28A11.2 Enriched in PLM; body wall muscle cell; and muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by ten chemicals including 1-methylnicotinamide; rotenone; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00020870 T28A11.3 Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00020871 T28A11.4 Enriched in dopaminergic neurons; muscle cell; and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including copper sulfate; multi-walled carbon nanotube; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00020872 T28A11.5 Enriched in GABAergic neurons; body wall muscle cell; and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including npr-1; lin-35; and dcr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; Mercuric Chloride; and paraquat based on microarray and RNA-seq studies. WB:WBGene00020873 T28A11.6 Enriched in DA neuron; VA neuron; body wall muscle cell; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Tunicamycin; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00020874 srbc-5 Predicted to be located in membrane. WB:WBGene00020875 T28A11.13 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including sir-2.1; lin-35; and lin-15B based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Thioredoxin-like superfamily; and Thioredoxin-like. Is an ortholog of human NXNL2 (nucleoredoxin like 2). WB:WBGene00020876 T28A11.14 No description available WB:WBGene00020877 srt-63 Predicted to be located in membrane. Expressed in neurons. WB:WBGene00020878 T28A11.16 Enriched in body wall muscle cell; intestine; and muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Mercuric Chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00020879 T28A11.17 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00020880 T28A11.18 Enriched in muscle cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; paraquat; and Ag nanoparticles based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00020881 T28A11.19 Enriched in coelomocyte; dopaminergic neurons; mechanosensory neurons; muscle cell; and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty chemicals including Mercuric Chloride; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00020882 T28A11.20 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00020883 fbxa-64 Expressed in body wall musculature; ventral nerve cord; and vulval muscle. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00020884 T28B4.1 Predicted to be involved in positive regulation of protein ubiquitination. Predicted to be part of SCF ubiquitin ligase complex. Expressed in body wall musculature and vulval muscle. Is an ortholog of human FBXL17 (F-box and leucine rich repeat protein 17). WB:WBGene00020885 T28B4.2 Enriched in CEM; HOB; IL2 neuron; and ray neuron type B based on RNA-seq studies. Is affected by several genes including eat-2; aak-2; and smg-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020886 ttr-6 Located in nucleus. WB:WBGene00020887 hic-1 Predicted to be located in membrane. Expressed in cholinergic neurons; head; tail; and ventral nerve cord. WB:WBGene00020888 T28C12.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00020889 T28C12.2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00020890 fbxa-202 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00020891 cest-24 Predicted to enable carboxylic ester hydrolase activity. Expressed in hypodermis and seam cell. WB:WBGene00020892 T28C12.5 Expressed in neurons. WB:WBGene00020893 T28C12.6 Predicted to enable peptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00020894 T28D9.1 Enriched in several structures, including distal tip cell; germ line; neurons; rectal epithelial cell; and terminal bulb based on Chronogram; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by eight chemicals including rotenone; Linolenic Acids; and Psoralens based on RNA-seq and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020895 plpp-1.2 Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. Is an ortholog of human PLPP3 (phospholipid phosphatase 3). WB:WBGene00020896 T28D9.4 Predicted to be located in membrane. WB:WBGene00020897 del-10 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. WB:WBGene00020898 lido-16 Predicted to be located in nucleus. WB:WBGene00020899 T28D9.11 Is affected by several genes including daf-16; clk-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00020900 T28F2.1 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00020901 T28F2.2 Enriched in several structures, including ABplapaaaap; ABplapaaap; ABprapaaaap; ABprapaaap; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; npr-1; and lin-35 based on quantitative PCR; microarray; and RNA-seq studies. Is affected by eight chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: COMM domain-containing protein 4/6/7/8. Is an ortholog of human COMMD4 (COMM domain containing 4). WB:WBGene00020902 jmjc-1 Predicted to enable histone H3K36 demethylase activity; histone H3K4me/H3K4me2/H3K4me3 demethylase activity; and iron ion binding activity. Involved in several processes, including response to ethanol; response to heat; and response to osmotic stress. Predicted to be located in nucleolus. Is an ortholog of human RIOX1 (ribosomal oxygenase 1). WB:WBGene00020903 acd-5 Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Expressed in intestinal cell. WB:WBGene00020904 T28F12.1 Predicted to be located in membrane. WB:WBGene00020905 T28H11.7 Enriched in excretory cell; intestine; muscle cell; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including Ethanol; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily. WB:WBGene00020906 T28H11.8 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in excretory cell. WB:WBGene00020908 VC5.2 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and body wall musculature based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by nine chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Nematode polyprotein allergen ABA-1; Polyprotein allergen, nematode; Laminin EGF domain; DVA-1 superfamily; Laminin-type EGF domain; and EGF-like domain. WB:WBGene00020909 W01A11.1 Predicted to enable epoxide hydrolase activity. Predicted to be involved in epoxide metabolic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Leber hereditary optic neuropathy; hematologic cancer (multiple); and lung disease (multiple). Is an ortholog of human EPHX1 (epoxide hydrolase 1). WB:WBGene00020910 dgtr-1 Predicted to enable diacylglycerol O-acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Located in sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease. Is an ortholog of human MOGAT1 (monoacylglycerol O-acyltransferase 1). WB:WBGene00020911 cpt-6 Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in carnitine metabolic process and fatty acid metabolic process. Predicted to be located in mitochondrion. Expressed in hypodermis. WB:WBGene00020912 W01A11.7 Enriched in several structures, including ABalaapppp; ABalapaapp; excretory cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Lithium Chloride; aldicarb; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00020913 W01B11.1 Predicted to be located in membrane. WB:WBGene00020914 sulp-6 Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in several diseases, including Pendred Syndrome; autosomal recessive nonsyndromic deafness (multiple); and bone disease (multiple). Is an ortholog of several human genes including SLC26A2 (solute carrier family 26 member 2); SLC26A3 (solute carrier family 26 member 3); and SLC26A4 (solute carrier family 26 member 4). WB:WBGene00020915 nol-58 Predicted to enable snoRNA binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in nucleolus. Predicted to be part of box C/D RNP complex and small-subunit processome. Is an ortholog of human NOP58 (NOP58 ribonucleoprotein). WB:WBGene00020917 W01B11.6 Enriched in several structures, including AIZ; coelomocyte; germline precursor cell; head mesodermal cell; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-five chemicals including rotenone; 4-bromodiphenyl ether; and levamisole based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in male infertility. Human TXNDC2 enables thioredoxin-disulfide reductase (NADP) activity. Is predicted to encode a protein with the following domains: Thioredoxin domain; Thioredoxin; and Thioredoxin-like superfamily. Is an ortholog of human TXNDC2 (thioredoxin domain containing 2) and TXNDC8 (thioredoxin domain containing 8). WB:WBGene00020918 W01C8.1 Enriched in AVJL; AVJR; GABAergic neurons; excretory cell; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and drh-3 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00020919 set-19 Expressed in hypodermis. Is predicted to encode a protein with the following domains: SET domain superfamily and SET domain. WB:WBGene00020920 set-20 Expressed in hypodermis. Is predicted to encode a protein with the following domains: SET domain superfamily and SET domain. WB:WBGene00020921 W01C8.5 Enriched in several structures, including ABalaappppa; excretory gland cell; hyp3; neurons; and pharyngeal cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and kidney failure (multiple). Is predicted to encode a protein with the following domains: Electron transfer DM13 and DM13 domain. Is an ortholog of human THBD (thrombomodulin). WB:WBGene00020922 W01H2.2 Enriched in DA neuron; GABAergic neurons; VA neuron; hypodermis; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and lin-39 based on tiling array and RNA-seq studies. Is affected by silicon dioxide nanoparticle and Sirolimus based on microarray studies. WB:WBGene00020923 W02B3.3 Enriched in NSM; dopaminergic neurons; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-12; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Chlorpyrifos; Diazinon; and allantoin based on microarray studies. WB:WBGene00020924 W02B3.4 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Is an ortholog of human FKTN (fukutin). WB:WBGene00020927 W02B3.7 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Is an ortholog of human FKTN (fukutin). WB:WBGene00020929 W02C12.2 Predicted to be located in membrane. WB:WBGene00020930 hlh-30 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including defense response to bacterium; determination of adult lifespan; and positive regulation of metabolic process. Acts upstream of or within positive regulation of plasma membrane repair and positive regulation of xenophagy. Located in cytoplasm and nucleus. Expressed in several structures, including nerve ring; rectal valve cell; somatic cell; spermatheca; and vulva. Human ortholog(s) of this gene implicated in several diseases, including Tietz syndrome; Tietze's syndrome; and Waardenburg syndrome type 2A. Is an ortholog of human TFE3 (transcription factor binding to IGHM enhancer 3) and TFEC (transcription factor EC). WB:WBGene00020931 cytb-5.2 Predicted to enable heme binding activity. Predicted to be located in intracellular membrane-bounded organelle and membrane. Human ortholog(s) of this gene implicated in methemoglobinemia; methemoglobinemia and ambiguous genitalia; and stomatitis. Is an ortholog of human CYB5A (cytochrome b5 type A). WB:WBGene00020932 dhod-1 Predicted to enable dihydroorotate dehydrogenase activity. Predicted to be involved in 'de novo' pyrimidine nucleobase biosynthetic process and pyrimidine ribonucleotide biosynthetic process. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in postaxial acrofacial dysostosis. Is an ortholog of human DHODH (dihydroorotate dehydrogenase (quinone)). WB:WBGene00020933 W02D3.4 Predicted to enable carbohydrate transmembrane transporter activity. Predicted to be involved in carbohydrate transmembrane transport. Predicted to be located in membrane. Is an ortholog of human TMEM144 (transmembrane protein 144). WB:WBGene00020935 fnci-1 Predicted to enable DNA polymerase binding activity. Predicted to be involved in DNA repair. WB:WBGene00020936 hrpf-1 Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleoplasm. Predicted to be part of ribonucleoprotein complex. Expressed widely. WB:WBGene00020937 W02D3.12 Predicted to be involved in mitochondrial respiratory chain complex II assembly. Predicted to be located in mitochondrion. Is an ortholog of human SDHAF4 (succinate dehydrogenase complex assembly factor 4). WB:WBGene00020938 clec-218 Involved in defense response to Gram-positive bacterium. WB:WBGene00020939 smex-1 Predicted to be located in membrane. WB:WBGene00020940 W02D7.4 Predicted to enable N-acetyltransferase activity. WB:WBGene00020941 W02D7.5 Predicted to enable N-acetyltransferase activity. WB:WBGene00020942 W02D7.6 Enriched in germ line; intestine; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and gld-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; Zidovudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00020943 W02D7.8 Predicted to be located in membrane. WB:WBGene00020944 W02D7.9 Enriched in AFD; NSM; and body wall muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including clk-1; aak-2; and mex-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020945 clec-219 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Expressed in vas deferens. WB:WBGene00020946 W02D7.11 Predicted to be located in membrane. WB:WBGene00020947 W02F12.2 Predicted to enable N-acylsphingosine amidohydrolase activity. Predicted to be involved in ceramide catabolic process and sphingosine biosynthetic process. Predicted to be located in Golgi membrane. Is an ortholog of human ACER1 (alkaline ceramidase 1). WB:WBGene00020948 era-1 Located in cell cortex. Expressed in several structures, including AB; AB lineage cell; ABa; ABp; and germ line. WB:WBGene00020949 W02F12.4 Predicted to enable 3'-5'-DNA exonuclease activity. Predicted to be involved in DNA metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome; lupus erythematosus (multiple); and retinal vasculopathy with cerebral leukodystrophy. Is an ortholog of human TREX1 (three prime repair exonuclease 1) and TREX2 (three prime repair exonuclease 2). WB:WBGene00020950 dlst-1 Predicted to enable dihydrolipoyllysine-residue succinyltransferase activity. Predicted to be involved in tricarboxylic acid cycle. Predicted to be located in mitochondrion. Predicted to be part of oxoglutarate dehydrogenase complex. Human ortholog(s) of this gene implicated in Alzheimer's disease and paraganglioma. Is an ortholog of human DLST (dihydrolipoamide S-succinyltransferase). WB:WBGene00020951 sna-1 Predicted to enable transcription coactivator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of core mediator complex and mediator complex. Expressed in several structures, including germ cell and somatic cell. WB:WBGene00020952 kel-8 Involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Located in neuron projection; neuronal cell body; and postsynaptic density. Part of Cul3-RING ubiquitin ligase complex. Expressed in command interneuron and intestine. Is an ortholog of human KLHL8 (kelch like family member 8). WB:WBGene00020953 W02G9.3 Predicted to enable RNA binding activity. Predicted to be involved in tRNA modification. Is an ortholog of human THUMPD1 (THUMP domain containing 1). WB:WBGene00020954 W02G9.4 Enriched in intestine; neurons; and retrovesicular ganglion based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including Heme; rotenone; and mianserin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily and CUB domain. Is an ortholog of human CDCP2 (CUB domain containing protein 2). WB:WBGene00020955 angl-1 Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, exonucleolytic. Expressed in PDB; body wall musculature; intestine; pharyngeal muscle cell; and ventral cord neurons. Is an ortholog of human ANGEL1 (angel homolog 1) and ANGEL2 (angel homolog 2). WB:WBGene00020957 W02H5.2 Predicted to enable actin filament binding activity. Predicted to be involved in cellular response to amino acid starvation and negative regulation of TORC1 signaling. Predicted to be located in lamellipodium. WB:WBGene00020958 W02H5.3 No description available WB:WBGene00020959 W02H5.4 No description available WB:WBGene00020961 sknr-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; liver disease (multiple); obesity; and pulmonary emphysema. Is an ortholog of several human genes including NFE2 (nuclear factor, erythroid 2); NFE2L1 (NFE2 like bZIP transcription factor 1); and NFE2L2 (NFE2 like bZIP transcription factor 2). WB:WBGene00020962 W02H5.8 Predicted to enable glycerone kinase activity. Predicted to be involved in glycerol catabolic process. Predicted to be located in cytosol. Is an ortholog of human TKFC (triokinase and FMN cyclase). WB:WBGene00020964 polq-1 Predicted to enable DNA-directed DNA polymerase activity. Involved in base-excision repair, gap-filling and cellular response to ionizing radiation. Predicted to be located in nucleus. Is an ortholog of human POLQ (DNA polymerase theta). WB:WBGene00020966 W03A5.1 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be part of receptor complex. WB:WBGene00020967 W03A5.2 Predicted to be located in membrane. WB:WBGene00020970 W03A5.6 Predicted to enable molecular adaptor activity. Predicted to be involved in phosphorylation and signaling. Predicted to be located in glutamatergic synapse and postsynaptic specialization. Is an ortholog of human DLGAP1 (DLG associated protein 1). WB:WBGene00020971 W03B1.1 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including methylmercuric chloride; Sodium Chloride; and metformin based on microarray and RNA-seq studies. WB:WBGene00020972 trpl-2 Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in membrane. WB:WBGene00020973 W03B1.3 Enriched in OLL; PVD; seam cell; and tail precursor cell based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including mianserin; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily. WB:WBGene00020974 W03B1.5 Is affected by several genes including daf-2; pie-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including hydrogen sulfide; multi-walled carbon nanotube; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00020976 oac-51 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00020977 oac-52 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00020978 W03B1.9 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Sodium Chloride; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00020979 fbxb-55 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00020981 W03D2.6 Enriched in OLL; PVD; and intestine based on microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including rotenone; manganese chloride; and D-glucopyranose based on RNA-seq and microarray studies. WB:WBGene00020982 ilys-6 Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-positive bacterium. Expressed in coelomocyte; intestine; and pharyngeal gland cell. WB:WBGene00020983 W03D2.9 Enriched in AFD and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-10; rrf-3; and let-7 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq and microarray studies. WB:WBGene00020984 W03D8.1 Enriched in muscle cell and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including D-glucose; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00020985 W03D8.2 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00020986 W03D8.3 Predicted to be located in membrane. WB:WBGene00020987 W03D8.5 Predicted to be located in cytoskeleton. WB:WBGene00020988 W03D8.7 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Alovudine; Sodium Chloride; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1265; SKP1/BTB/POZ domain superfamily; and Protein of unknown function (DUF1265). WB:WBGene00020989 W03D8.8 Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in disease of metabolism. Is an ortholog of several human genes including ACOT2 (acyl-CoA thioesterase 2); ACOT4 (acyl-CoA thioesterase 4); and BAAT (bile acid-CoA:amino acid N-acyltransferase). WB:WBGene00020990 W03D8.9 Predicted to be located in membrane. WB:WBGene00020991 W03D8.10 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; D-glucose; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00020992 W03F8.2 Enriched in neurons; retrovesicular ganglion; and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including rotenone; Tunicamycin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00020993 mtrf-1L Predicted to enable translation release factor activity. Predicted to be involved in mitochondrial translational termination. Predicted to be located in mitochondrion. Is an ortholog of human MTRF1L (mitochondrial translation release factor 1 like). WB:WBGene00020994 W03F8.4 Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to be located in cytosol and nucleus. Predicted to be part of EKC/KEOPS complex. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 5. Is an ortholog of human TPRKB (TP53RK binding protein). WB:WBGene00020995 W03F8.6 Predicted to be located in membrane. WB:WBGene00020997 gpa-18 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-activating dopamine receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be part of heterotrimeric G-protein complex. Expressed in neurons; tail; and in male. WB:WBGene00020999 W03F9.1 Predicted to enable zinc ion binding activity. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Is an ortholog of human ZPR1 (ZPR1 zinc finger). WB:WBGene00021000 W03F9.2 Enriched in several structures, including ABalappaap; ABalppppppa; ABplpaaaaa; ABplpaaaap; and head mesodermal cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; mianserin; and stavudine based on RNA-seq and microarray studies. WB:WBGene00021001 W03F9.3 Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00021002 W03F9.4 Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in carnitine metabolic process and fatty acid metabolic process. Predicted to be located in mitochondrion. WB:WBGene00021003 W03F9.9 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00021004 sftb-2 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U2 snRNP and spliceosomal complex. Expressed in head and tail. Human ortholog(s) of this gene implicated in Goldenhar syndrome. Is an ortholog of human SF3B2 (splicing factor 3b subunit 2). WB:WBGene00021005 ule-1 Predicted to enable chitin binding activity. Predicted to be located in extracellular region. WB:WBGene00021006 dct-9 Predicted to be located in cytoskeleton. WB:WBGene00021007 W03F11.4 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00021008 W03F11.5 Enriched in body wall musculature and seam cell based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including Heme; methylmercuric chloride; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00021009 afd-1 Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in regulation of protein localization. Predicted to be located in adherens junction. Human ortholog(s) of this gene implicated in Parkinson's disease and breast carcinoma. Is an ortholog of human AFDN (afadin, adherens junction formation factor). WB:WBGene00021010 W03G1.2 Enriched in OLL; PVD; body wall muscle cell; and in male based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF851 and Protein of unknown function (DUF851). WB:WBGene00021011 W03G1.5 Enriched in MSpppaaa; head mesodermal cell; intestine; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by eighteen chemicals including Mercuric Chloride; Tunicamycin; and Cadmium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterized Strongylid L4 protein and Uncharacterized strongylid L4 protein. WB:WBGene00021012 pig-1 Enables protein serine/threonine kinase activity. Involved in several processes, including generation of neurons; hemidesmosome assembly; and regulation of apoptotic process. Located in centrosome and cytoplasm. Expressed in several structures, including AVM; Q lineage cell; QL.aa; QL.pp; and nerve ring neurons. Is an ortholog of human MELK (maternal embryonic leucine zipper kinase). WB:WBGene00021013 W03G1.8 Enriched in AFD and AVK based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00021014 pid-4 Predicted to be involved in regulatory ncRNA-mediated gene silencing. Predicted to be located in P-body and perinuclear region of cytoplasm. WB:WBGene00021015 enu-3.3 Predicted to be involved in axon extension involved in axon guidance. Predicted to be located in neuronal cell body. WB:WBGene00021016 W03G9.5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00021017 cil-7 Located in neuronal cell body and plasma membrane bounded cell projection. Expressed in ciliated neurons. WB:WBGene00021018 W04B5.1 Enriched in several structures, including ASER; excretory cell; head mesodermal cell; intestine; and pharynx based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021019 W04B5.2 Enriched in several structures, including ABalaaaarl; ABalaaaarr; head mesodermal cell; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including aldicarb; hydrogen sulfide; and rotenone based on microarray and RNA-seq studies. WB:WBGene00021020 W04B5.3 Predicted to enable carbohydrate binding activity. WB:WBGene00021021 mrpl-30 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of large ribosomal subunit. Is an ortholog of human MRPL30 (mitochondrial ribosomal protein L30). WB:WBGene00021022 W04B5.5 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and prostate cancer. Is an ortholog of human PDPK1 (3-phosphoinositide dependent protein kinase 1) and PDPK2P (3-phosphoinositide dependent protein kinase 2, pseudogene). WB:WBGene00021023 W04B5.6 Enriched in intestine based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00021024 W04C9.2 Predicted to be involved in cristae formation. Predicted to be located in mitochondrial crista junction. Predicted to be part of MICOS complex. WB:WBGene00021025 cutl-13 Predicted to be located in membrane. WB:WBGene00021026 W04C9.4 Located in nucleolus. WB:WBGene00021027 W04C9.5 Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be located in plasma membrane. WB:WBGene00021028 W04C9.6 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00021029 W04D12.1 Enriched in dopaminergic neurons and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-12; clk-1; and nhr-25 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00021030 W04H10.1 Enriched in GLR based on single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and isp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021031 W04H10.2 Enriched in several structures, including ABalpapppa; ABarapappa; GLR; MSaaaaapa; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including 1-methylnicotinamide; methylmercuric chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00021032 clec-118 Enriched in coelomocyte and intestine based on tiling array and microarray studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Tunicamycin; multi-walled carbon nanotube; and resveratrol based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00021033 srz-32 Predicted to be located in membrane. Expressed in ADLL; ADLR; ASHL; and ASHR. WB:WBGene00021034 enu-3.4 Enriched in RIM; germ line; germline precursor cell; and interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including allantoin; Sirolimus; and antimycin based on RNA-seq and microarray studies. WB:WBGene00021035 W05F2.3 Predicted to be located in membrane. Expressed in germ line. WB:WBGene00021036 W05F2.4 Expressed in body wall musculature and vulval muscle. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021037 fbxa-203 Enriched in germ line; germline precursor cell; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including manganese chloride; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021038 W05F2.6 Enriched in enteric muscle; germ line; germline precursor cell; head mesodermal cell; and seam cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including manganese chloride; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021039 W05F2.7 Enriched in several structures, including ABalppppppa; ABpraaapppa; amphid neurons; interfacial epithelial cell; and pharyngeal-intestinal valve cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including glp-1; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by four chemicals including rotenone; paraquat; and Chlorpyrifos based on RNA-seq and microarray studies. WB:WBGene00021040 W05G11.2 Enriched in germ line based on RNA-seq studies. Is affected by several genes including glp-1; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; manganese chloride; and stavudine based on microarray and RNA-seq studies. WB:WBGene00021041 clp-10 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human CAPN15 (calpain 15). WB:WBGene00021042 btb-5 Enriched in AVK; GABAergic neurons; and rect_D based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00021043 pck-1 Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Located in cytosol and striated muscle dense body. Expressed in several structures, including body wall musculature; preanal ganglion; somatic nervous system; tail ganglion; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is an ortholog of human PCK1 (phosphoenolpyruvate carboxykinase 1). WB:WBGene00021044 W05H7.1 Enriched in muscle cell and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021045 W05H7.2 Is affected by several genes including daf-16; skn-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including silicon dioxide nanoparticle; Chlorpyrifos; and Diazinon based on microarray studies. WB:WBGene00021046 sedl-1 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in cytoplasm and nucleus. Predicted to be part of TRAPP complex. Human ortholog(s) of this gene implicated in X-linked spondyloepiphyseal dysplasia tarda. Is an ortholog of human TRAPPC2 (trafficking protein particle complex subunit 2) and TRAPPC2B (trafficking protein particle complex subunit 2B). WB:WBGene00021047 zfp-3 Predicted to enable metal ion binding activity. Located in nucleus. WB:WBGene00021048 W05H9.1 Predicted to be located in membrane. WB:WBGene00021049 W05H9.2 Enriched in germ line; neurons; and somatic gonad precursor based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including D-glucose; stavudine; and paraquat based on RNA-seq and microarray studies. WB:WBGene00021050 W05H9.3 Enriched in several structures, including coelomocyte; excretory cell; interneuron; intestine; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00021051 W05H9.4 Enriched in several structures, including ABalpapppa; ABarapappa; germ line; neurons; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; pgl-1; and fog-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00021052 W06A11.1 Enriched in several structures, including PLM; anterior hypodermis; interfacial epithelial cell; rectal gland cell; and tail hypodermis based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00021053 gadr-4 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00021054 fbxb-118 Enriched in AFD; XXXL; XXXR; and Y cell based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including 1-methylnicotinamide; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021055 W06A11.4 Expressed in intestinal cell. WB:WBGene00021056 W06B4.1 Predicted to enable N-acetylglucosamine kinase activity. Predicted to be involved in carbohydrate phosphorylation. Is an ortholog of human NAGK (N-acetylglucosamine kinase). WB:WBGene00021057 W06B4.2 Predicted to enable N-acetylglucosamine kinase activity. Predicted to be involved in carbohydrate phosphorylation. Is an ortholog of human NAGK (N-acetylglucosamine kinase). WB:WBGene00021058 vps-18 Predicted to enable protein-macromolecule adaptor activity. Involved in endosome organization and phagosome-lysosome fusion involved in apoptotic cell clearance. Located in cytoplasm. Expressed in body wall musculature; coelomocyte; hermaphrodite gonad; hypodermis; and intestine. Is an ortholog of human VPS18 (VPS18 core subunit of CORVET and HOPS complexes). WB:WBGene00021059 atat-2 Enables tubulin N-acetyltransferase activity. Involved in thigmotaxis. Predicted to be located in microtubule. Expressed in ciliated neurons and touch receptor neurons. Is an ortholog of human ATAT1 (alpha tubulin acetyltransferase 1). WB:WBGene00021060 dct-11 Predicted to be located in lysosomal membrane. WB:WBGene00021061 W06E11.1 Predicted to be involved in tRNA transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is an ortholog of human POLR3E (RNA polymerase III subunit E). WB:WBGene00021063 sbds-1 Predicted to be involved in cytosolic ribosome assembly. Predicted to be located in cytoplasm; nuclear lumen; and spindle. Human ortholog(s) of this gene implicated in Shwachman-Diamond syndrome and aplastic anemia. Is an ortholog of human SBDS (SBDS ribosome maturation factor). WB:WBGene00021066 W06H8.2 Predicted to enable FMN binding activity and oxidoreductase activity. WB:WBGene00021067 W06H8.4 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00021068 W06H8.6 Expressed in body wall musculature; pharyngeal muscle cell; and vulval muscle. WB:WBGene00021070 cpr-8 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). WB:WBGene00021072 W07B8.4 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). WB:WBGene00021073 nsun-1 Enables rRNA (cytosine-C5-)-methyltransferase activity. Involved in several processes, including negative regulation of cellular response to heat; negative regulation of locomotion involved in locomotory behavior; and positive regulation of reproductive process. Predicted to be located in nucleolus. Expressed widely. Used to study Williams-Beuren syndrome. Is an ortholog of human NOP2 (NOP2 nucleolar protein). WB:WBGene00021074 gldi-1 Predicted to be involved in Notch signaling pathway and ribosomal large subunit assembly. Predicted to be located in nucleolus. Is an ortholog of human NLE1 (notchless homolog 1). WB:WBGene00021075 sms-5 Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to be located in membrane. Expressed in marginal cell; pharyngeal muscle cell; pharynx; and spermatheca. WB:WBGene00021076 W07E6.5 Predicted to be located in membrane. WB:WBGene00021077 W07E6.6 No description available WB:WBGene00021078 unc-132 Predicted to enable GTP binding activity; phosphatidic acid binding activity; and phosphatidylinositol binding activity. Predicted to be involved in photoreceptor cell maintenance. WB:WBGene00021079 W08A12.2 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00021080 W08A12.3 Predicted to be located in membrane. WB:WBGene00021081 pals-33 Enriched in body wall muscle cell; excretory cell; intestine; neurons; and retrovesicular ganglion based on tiling array and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including tryptophan; Mercuric Chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00021082 zip-11 Enables DNA-binding transcription factor binding activity. Involved in defense response to Gram-negative bacterium. Located in nucleus. WB:WBGene00021083 W08E12.2 Enriched in arcade cell; male-specific anatomical entity; and neurons based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-six chemicals including 1-methylnicotinamide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00021084 idpp-12 Expressed in pm8. WB:WBGene00021085 W08E12.4 Expressed in pharynx and pm8. WB:WBGene00021086 W08E12.5 Enriched in DA neuron; VA neuron; intestine; male-specific anatomical entity; and pharynx based on microarray; Chronogram; and RNA-seq studies. Is affected by several genes including dpy-10; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Neurotoxins; silicon dioxide nanoparticle; and Oligosaccharides based on microarray and RNA-seq studies. WB:WBGene00021087 W08E12.6 Enriched in DA neuron and VA neuron based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including 1-methylnicotinamide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00021088 W08E12.7 Expressed in gonad and pharynx. Human PA2G4 enables nucleic acid binding activity; transcription corepressor activity; and ubiquitin protein ligase binding activity. Is predicted to encode a protein with the following domains: PA2G4 family; Creatinase/aminopeptidase-like; Metallopeptidase family M24; Winged helix DNA-binding domain superfamily; Winged helix-like DNA-binding domain superfamily; Peptidase M24; Proliferation-associated protein 2G4/ARX1; and Phosphorylation site. Is an ortholog of human PA2G4 (proliferation-associated 2G4). WB:WBGene00021089 W08E12.8 Enriched in several structures, including AFD; PLM; male distal tip cell; seam cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including nicotinic acid; D-glucose; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00021090 W08E12.9 Enriched in ABalaaaala; ABalaapaaa; male-specific anatomical entity; and pm8 based on single-cell RNA-seq and microarray studies. Is affected by several genes including rrf-3; sir-2.1; and csr-1 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00021091 W08F4.1 Predicted to enable nucleic acid binding activity. WB:WBGene00021092 fbxb-34 Enriched in AIBL; AIBR; and Y cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021093 W08F4.3 Predicted to be located in endoplasmic reticulum. Expressed in tail. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and distal spinal muscular atrophy 2. Is an ortholog of human SIGMAR1 (sigma non-opioid intracellular receptor 1). WB:WBGene00021094 W08F4.5 Enriched in hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00021095 mlt-8 Predicted to enable lipid transporter activity. Predicted to be involved in ganglioside catabolic process and lipid transport. Predicted to be located in cytoplasmic side of plasma membrane. Expressed in cuticle and hypodermal cell. WB:WBGene00021096 W08F4.7 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and hsp-6 based on microarray and RNA-seq studies. Is affected by D-glucose and adsorbable organic bromine compound based on RNA-seq and microarray studies. WB:WBGene00021097 cdc-37 Predicted to enable heat shock protein binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in protein folding and protein stabilization. Located in condensed chromosome; cytoplasm; and mitotic spindle. Expressed in anchor cell. Is an ortholog of human CDC37 (cell division cycle 37, HSP90 cochaperone). WB:WBGene00021098 fbxb-14 Enriched in I5 neuron; cholinergic neurons; and retrovesicular ganglion based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; clk-1; and tph-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021099 W08F4.10 Enriched in ABplapaaaa; ABprapaaaa; AFD; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including clk-1; hpl-2; and spn-4 based on tiling array; microarray; and RNA-seq studies. Is affected by Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021100 W08F4.11 Enriched in neurons and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; mex-3; and mex-1 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00021101 W08F4.12 Enriched in body wall muscle cell; neurons; and retrovesicular ganglion based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; rotenone; and sodium arsenite based on microarray and RNA-seq studies. WB:WBGene00021103 eri-3 Predicted to enable RNA-directed DNA polymerase activity. Involved in spermatogenesis. WB:WBGene00021104 W09B6.4 Predicted to be involved in tRNA wobble uridine modification. Predicted to be located in cytoplasm and nucleus. Predicted to be part of elongator holoenzyme complex. WB:WBGene00021106 W09B7.1 Expressed in intestinal cell. WB:WBGene00021107 W09B7.2 Expressed in intestinal cell. WB:WBGene00021108 W09B7.3 Is affected by allantoin based on microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00021109 W09C3.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00021110 W09C3.2 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by sixteen chemicals including aldicarb; hydrogen sulfide; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00021111 W09C3.3 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00021112 W09C3.4 Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human POLR3F (RNA polymerase III subunit F). WB:WBGene00021113 gsp-3 Predicted to enable protein serine/threonine phosphatase activity. Involved in regulation of pseudopodium assembly and reproductive process. Located in cytoplasm and pseudopodium. Part of chromatin. Expressed in sperm. WB:WBGene00021114 W09C3.7 Enriched in several structures, including germ line; gonadal sheath cell; head mesodermal cell; hypodermis; and sperm based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00021115 W09C3.8 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including manganese chloride; Alovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00021116 ncs-6 Predicted to enable calcium ion binding activity. WB:WBGene00021117 clec-126 Enriched in ABaraappaa; AVK; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including D-glucose; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021118 clec-125 Enriched in germ line; neurons; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including rrf-3; eat-2; and pmk-1 based on RNA-seq and microarray studies. Is affected by eighteen chemicals including aldicarb; methylmercury hydroxide; and Mercuric Chloride based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and Phosphorylation site. WB:WBGene00021120 W09G12.6 Enriched in intestine; sensory neurons; and in male based on RNA-seq and microarray studies. Is affected by several genes including rrf-3; eat-2; and dcr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021121 W09G12.7 Enriched in OLL; PVD; and in male based on microarray and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by twenty chemicals including Nitric Oxide; 1-methylnicotinamide; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021122 W09G12.8 Predicted to be involved in glycoprotein catabolic process. Predicted to be located in cytoplasm. WB:WBGene00021123 W09G12.9 Predicted to be located in membrane. WB:WBGene00021124 W10C4.1 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00021125 ccb-2 Predicted to enable high voltage-gated calcium channel activity. Predicted to be involved in chemical synaptic transmission and neuromuscular junction development. Predicted to be located in synapse. Predicted to be part of voltage-gated calcium channel complex. Expressed in head neurons and ventral nerve cord. WB:WBGene00021127 W10C8.4 Enriched in excretory gland cell; pharyngeal cell; and touch receptor neurons based on tiling array; microarray; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by thirteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Human GSTA1 enables several functions, including glutathione peroxidase activity; glutathione transferase activity; and steroid delta-isomerase activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal domain; and Glutathione S-transferase, C-terminal. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3). WB:WBGene00021128 W10C8.5 Predicted to enable kinase activity. Predicted to be involved in phosphocreatine biosynthetic process and phosphorylation. Is an ortholog of several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1B (creatine kinase, mitochondrial 1B). WB:WBGene00021129 W10D9.1 Predicted to be located in membrane. WB:WBGene00021130 W10D9.2 Is affected by several genes including daf-2; sir-2.1; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00021131 W10D9.3 Enriched in Caapa; body wall muscle cell; germ line; intestine; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; isp-1; and hlh-30 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Cry5B; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4796 and Domain of unknown function (DUF4796). Is an ortholog of human MKRN2OS (MKRN2 opposite strand). WB:WBGene00021132 nfyb-1 Enables DNA-binding transcription repressor activity. Involved in regulation of gene expression and tissue development. Located in cytoplasm and perikaryon. Expressed in several structures, including excretory cell; gonad; muscle cell; neurons; and oocyte. Is an ortholog of human NFYB (nuclear transcription factor Y subunit beta). WB:WBGene00021133 tomm-22 Predicted to be involved in intracellular protein transport. Predicted to be located in mitochondrial outer membrane. Is an ortholog of human TOMM22 (translocase of outer mitochondrial membrane 22). WB:WBGene00021134 W10G11.1 Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00021135 W10G11.2 Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Rifampin; mianserin; and D-glucopyranose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00021136 W10G11.3 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including methylmercuric chloride; Rifampin; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00021137 W10G11.4 Is affected by several genes including clk-1; isp-1; and unc-30 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including tryptophan; mianserin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00021138 clec-127 Enriched in NSM based on tiling array studies. Is affected by daf-2 based on RNA-seq and microarray studies. Is affected by Atrazine and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021139 clec-128 Enriched in NSM based on tiling array studies. Is affected by daf-2; daf-18; and eat-2 based on RNA-seq and microarray studies. Is affected by resveratrol; fluoranthene; and adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and Phosphorylation site. WB:WBGene00021140 clec-131 Is affected by cyc-1 and rsr-2 based on microarray and tiling array studies. Is affected by fluoranthene based on microarray studies. WB:WBGene00021141 clec-134 Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; C-type lectin-like/link domain superfamily; and PAN-3 domain. WB:WBGene00021142 clec-133 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Alovudine; stavudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021143 clec-132 Enriched in NSM based on tiling array studies. Is affected by lpd-3 based on RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00021144 clec-130 Enriched in male based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including silicon dioxide nanoparticle; Atrazine; and cadmium based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021145 clec-129 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021146 lgc-45 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00021148 W10G11.19 Enriched in AFD; head mesodermal cell; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including Lithium Chloride; Zidovudine; and paraquat based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Thioredoxin domain-containing protein 16 and Thioredoxin-like superfamily. WB:WBGene00021149 dnc-3 Part of dynactin complex. WB:WBGene00021150 Y1B5A.1 Enriched in intestine based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00021151 Y4C6A.1 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; manganese chloride; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00021152 mgl-3 Predicted to enable adenylate cyclase inhibiting G protein-coupled glutamate receptor activity. Involved in positive regulation of lipid storage. Predicted to be located in plasma membrane. Expressed in NSM; head neurons; and nerve ring. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; autistic disorder; and congenital stationary night blindness 1B. Is an ortholog of human GRM8 (glutamate metabotropic receptor 8). WB:WBGene00021153 Y4C6A.3 Predicted to enable metal ion binding activity. Predicted to be located in membrane. WB:WBGene00021154 Y4C6A.4 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-2; skn-1; and let-60 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; manganese chloride; and allantoin based on microarray and RNA-seq studies. WB:WBGene00021155 Y4C6B.1 Enriched in several structures, including ABalpapppa; ABarapappa; Caapa; germ line; and male distal tip cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00021156 Y4C6B.2 Predicted to be located in membrane. WB:WBGene00021157 Y4C6B.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00021158 Y4C6B.4 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00021159 slc-46A Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in intestine and pharyngeal neurons. Human ortholog(s) of this gene implicated in hereditary folate malabsorption. Is an ortholog of human SLC46A1 (solute carrier family 46 member 1). WB:WBGene00021160 gba-4 Predicted to enable glucosylceramidase activity. Predicted to be involved in glucosylceramide catabolic process. Human ortholog(s) of this gene implicated in several diseases, including Gaucher's disease (multiple); Lewy body dementia; and Netherton syndrome. Is an ortholog of human GBA1 (glucosylceramidase beta 1). WB:WBGene00021161 Y4C6B.7 Enriched in body wall muscle cell; dopaminergic neurons; g2L; g2R; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00021162 Y5H2A.1 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Heme; methylmercuric chloride; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00021163 nhr-275 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00021164 svh-11 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Involved in positive regulation of axon regeneration. Predicted to be located in Golgi cisterna membrane. WB:WBGene00021165 Y5H2B.3 Enriched in head ganglion; hypodermis; and pharyngeal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including diallyl trisulfide; methylmercuric chloride; and Mercuric Chloride based on microarray and RNA-seq studies. WB:WBGene00021166 srbc-42 Predicted to be located in membrane. WB:WBGene00021167 cyp-32B1 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. WB:WBGene00021168 cyp-33C12 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and lung disease (multiple). Is an ortholog of several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). WB:WBGene00021169 srt-40 Predicted to be located in membrane. WB:WBGene00021170 arx-4 Predicted to enable actin filament binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in epithelial cell migration and morphogenesis of embryonic epithelium. Predicted to be located in actin cytoskeleton and cytoplasm. Predicted to be part of Arp2/3 protein complex. Expressed in head and tail. Human ortholog(s) of this gene implicated in several diseases, including colorectal adenocarcinoma; invasive ductal carcinoma; and systemic scleroderma. Is an ortholog of human ARPC2 (actin related protein 2/3 complex subunit 2). WB:WBGene00021171 Y8A9A.2 Expressed in g1P; g2L; and g2R. Is predicted to encode a protein with the following domains: Thrombospondin type-1 (TSP1) repeat; Thrombospondin type 1 domain; and Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00021173 Y8A9A.4 Enriched in Z1.p; Z4.a; male distal tip cell; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; elt-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00021174 fbxb-99 Enriched in several structures, including ABplpppppp; ABprpppppp; B cell; DVA; and body muscle cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021175 math-46 Enriched in NSM based on tiling array studies. Is affected by several genes including age-1; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; multi-walled carbon nanotube; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: DUF236 repeat. WB:WBGene00021176 txt-3 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00021177 Y9C9A.5 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00021178 Y9C9A.8 Enriched in OLL; PVD; head mesodermal cell; intestine; and pharyngeal muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including methylmercuric chloride; Mercuric Chloride; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00021179 fbxa-86 Is affected by several genes including skn-1; clk-1; and lin-35 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; Mercuric Chloride; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00021180 Y9C9A.13 Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00021181 srz-27 Expressed in ASHL; ASHR; ASIL; ASIR; and PVT. WB:WBGene00021182 srz-28 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including age-1; clk-1; and drh-3 based on microarray; tiling array; and RNA-seq studies. Is affected by cadmium based on microarray studies. WB:WBGene00021183 Y9C9A.16 Predicted to enable FAD binding activity and sulfide:quinone oxidoreductase activity. Predicted to be involved in sulfide oxidation, using sulfide:quinone oxidoreductase. Predicted to be located in mitochondrion. Is an ortholog of human SQOR (sulfide quinone oxidoreductase). WB:WBGene00021184 Y9C9A.17 Is affected by rsr-2; mir-34; and eat-2 based on tiling array and microarray studies. Is affected by tetrabromobisphenol A; allantoin; and Sirolimus based on microarray studies. WB:WBGene00021185 Y9C12A.1 Predicted to be located in membrane. Is an ortholog of human TP53I11 (tumor protein p53 inducible protein 11). WB:WBGene00021186 Y9D1A.1 Enriched in several structures, including germ line; intestinal muscle; neurons; rectal muscle; and terminal bulb based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; rotenone; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00021187 Y9D1A.2 Enriched in several structures, including ABalpapaap; ABarappaap; MSaapaapa; pharyngeal cell; and sensory neurons based on microarray; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by D-glucose; metformin; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00021188 Y13C8A.1 Enriched in AFD and lateral ganglion based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by eight chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021190 Y14H12A.1 Predicted to be located in membrane. WB:WBGene00021191 Y14H12B.1 Enriched in several structures, including NSM; germ line; intestine; rectal epithelial cell; and rectum based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and let-7 based on microarray; proteomic; and RNA-seq studies. Is affected by eleven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021192 Y14H12B.2 Enriched in several structures, including AVG; RIM; command interneuron; germ line; and rect_D based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00021193 math-44 Enriched in AFD; Z1.p; Z4.a; gon_male_dtc anterior; and gon_male_dtc posterior based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00021194 Y16E11A.2 No description available WB:WBGene00021195 Y17G9A.2 Predicted to be located in membrane. WB:WBGene00021196 Y17G9A.3 Is affected by several genes including nhr-25; atfs-1; and dpy-21 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF684. WB:WBGene00021197 Y17G9A.4 Predicted to be located in membrane. WB:WBGene00021198 npp-26 Enriched in several structures, including ABalaaaala; ABalaapaaa; AVA; NSM; and amphid neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including 1-methylnicotinamide; methylmercuric chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00021199 Y17G9B.2 Enriched in several structures, including ABalaaaala; ABalaapaaa; PVP; ciliated neurons; and head neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and tph-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; mianserin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00021200 cyp-31A3 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Involved in several processes, including asymmetric cell division; embryonic morphogenesis; and female gamete generation. Predicted to be located in membrane. Expressed in gonad and oocyte. Used to study Bietti crystalline corneoretinal dystrophy. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Is an ortholog of human CYP4V2 (cytochrome P450 family 4 subfamily V member 2). WB:WBGene00021201 Y17G9B.4 Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Is an ortholog of human PPID (peptidylprolyl isomerase D). WB:WBGene00021202 Y17G9B.5 Predicted to be involved in innate immune response and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to be located in mitochondrion. Is an ortholog of human ECSIT (ECSIT signaling integrator). WB:WBGene00021204 fbxb-77 Enriched in several structures, including ABalaaaarl; intestinal muscle; neurons; rectal epithelial cell; and rectum based on RNA-seq; tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on proteomic; microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021205 Y17G9B.8 Predicted to enable methylated histone binding activity. Predicted to be located in nucleus. Predicted to be part of SAGA complex. Human ortholog(s) of this gene implicated in diabetic retinopathy. Is an ortholog of human SGF29 (SAGA complex associated factor 29). WB:WBGene00021207 ptp-5.3 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00021208 Y18H1A.2 Enriched in several structures, including ABplaapapa; germ line; rectal epithelial cell; rectum; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Leukocyte receptor cluster member 1-like. Is an ortholog of human LENG1 (leukocyte receptor cluster member 1). WB:WBGene00021209 hgap-1 Predicted to enable GTPase activator activity. Involved in determination of adult lifespan. Predicted to be located in cytoplasm. Is an ortholog of human RALGAPA1 (Ral GTPase activating protein catalytic subunit alpha 1) and RALGAPA2 (Ral GTPase activating protein catalytic subunit alpha 2). WB:WBGene00021210 Y18H1A.4 Predicted to enable phosphatase activity. Predicted to be located in cytoplasm. WB:WBGene00021212 Y18H1A.8 Enriched in several structures, including anterior hypodermis; germ line; pharyngeal gland cell; posterior arcade cell; and rectal gland cell based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00021213 Y18H1A.9 Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Is an ortholog of human CPA6 (carboxypeptidase A6). WB:WBGene00021214 hasp-2 Predicted to enable histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human HASPIN (histone H3 associated protein kinase). WB:WBGene00021215 Y18H1A.11 Predicted to enable choline-phosphate cytidylyltransferase activity and phosphatidylcholine binding activity. Predicted to be involved in CDP-choline pathway. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia with cone-rod dystrophy. Is an ortholog of human PCYT1A (phosphate cytidylyltransferase 1A, choline) and PCYT1B (phosphate cytidylyltransferase 1B, choline). WB:WBGene00021216 Y19D10A.1 Is affected by several genes including eat-2; clk-1; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class r (Str) and Serpentine type 7TM GPCR chemoreceptor Str. WB:WBGene00021217 Y19D10A.2 Is affected by several genes including daf-16; eat-2; and pgl-1 based on tiling array and RNA-seq studies. Is affected by Atrazine based on microarray studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class r (Str) and Serpentine type 7TM GPCR chemoreceptor Str. WB:WBGene00021218 srd-76 Enriched in neurons based on microarray studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on microarray and RNA-seq studies. Is affected by allantoin based on microarray studies. WB:WBGene00021219 Y19D10A.4 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. WB:WBGene00021220 Y19D10A.5 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. WB:WBGene00021221 Y19D10A.6 Predicted to enable metalloendopeptidase activity and zinc ion binding activity. Predicted to be involved in proteolysis. WB:WBGene00021222 irld-53 Enriched in DD neuron; intestine; and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray; quantitative PCR; tiling array; and RNA-seq studies. Is affected by ten chemicals including fluvastatin; Progesterone; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00021223 Y19D10A.8 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. WB:WBGene00021224 clec-209 Enriched in DA neuron; DD neuron; VA neuron; intestine; and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-five chemicals including manganese chloride; D-glucose; and stavudine based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021225 Y19D10A.10 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by several genes including rrf-3; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021226 Y19D10A.11 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. WB:WBGene00021227 mct-1 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Expressed in pharynx. Is an ortholog of human SLC16A4 (solute carrier family 16 member 4). WB:WBGene00021228 str-265 Predicted to be located in membrane. WB:WBGene00021230 Y19D10B.1 Is affected by several genes including daf-2; daf-12; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Zidovudine based on RNA-seq studies. WB:WBGene00021232 irld-15 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including aak-2; unc-30; and mex-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00021233 Y19D10B.4 Is affected by several genes including daf-16; daf-2; and hsf-1 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; Zidovudine; and graphene oxide based on RNA-seq studies. WB:WBGene00021234 irld-16 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-1; daf-3; and unc-75 based on RNA-seq and microarray studies. Is affected by dibromoacetic acid; dafa#1; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00021235 Y19D10B.6 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00021236 pud-1.2 Expressed in hypodermis and intestine. Is predicted to encode a protein with the following domains: Up-regulated in Daf-2 and Up-Regulated in long-lived daf-2. WB:WBGene00021237 crtc-1 Enables cAMP response element binding protein binding activity. Involved in determination of adult lifespan. Located in cytosol and nucleus. Expressed in RICL; RICR; head neurons; intestine; and tail neurons. Is an ortholog of human CRTC1 (CREB regulated transcription coactivator 1). WB:WBGene00021238 gap-3 Predicted to enable receptor tyrosine kinase binding activity and signaling adaptor activity. Involved in chemosensory behavior; learning or memory; and negative regulation of MAPK cascade. Expressed in several structures, including body wall musculature; egg-laying apparatus; germ cell; head neurons; and spermatheca. Human ortholog(s) of this gene implicated in arteriovenous malformation and basal cell carcinoma. Is an ortholog of human RASA1 (RAS p21 protein activator 1). WB:WBGene00021239 Y20F4.4 Enriched in enteric muscle; germ line; neuronal sheath cell; neurons; and rectal muscle based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by silicon dioxide nanoparticle; paraquat; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021240 Y20F4.5 No description available WB:WBGene00021241 Y22D7AL.1 Predicted to be located in membrane. WB:WBGene00021243 Y22D7AL.3 Predicted to be located in membrane. WB:WBGene00021244 Y22D7AL.4 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapapapa; ABalapappaa; and head neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including pgl-1; csr-1; and mex-3 based on RNA-seq and microarray studies. Is affected by five chemicals including Sodium Chloride; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021245 Y22D7AL.6 Enriched in several structures, including ABalpapaap; ABarappaap; hypodermal cell; interfacial epithelial cell; and mechanosensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; multi-walled carbon nanotube; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00021246 Y22D7AL.7 Enriched in several structures, including ABalpppppa; ABpraaappa; germ line; germline precursor cell; and neurons based on RNA-seq; tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; dpy-10; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Zidovudine; antimycin; and paraquat based on RNA-seq and microarray studies. WB:WBGene00021247 Y22D7AL.9 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and arc ant V based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Tetratricopeptide-like helical domain superfamily and Tetratricopeptide repeat. WB:WBGene00021248 Y22D7AL.10 Predicted to enable metal ion binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to be located in mitochondrial matrix. Is an ortholog of human HSPE1 (heat shock protein family E (Hsp10) member 1). WB:WBGene00021249 Y22D7AL.11 Enriched in AFD and PLM based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including sodium arsenite; Psoralens; and allantoin based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in Fukuyama congenital muscular dystrophy; Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2L; autosomal recessive limb-girdle muscular dystrophy type 2M; dilated cardiomyopathy (multiple); and muscular dystrophy-dystroglycanopathy type B4. Human FKTN enables phosphotransferase activity, for other substituted phosphate groups. Is predicted to encode a protein with the following domain: Ribitol-5-phosphate transferase FKTN-related. Is an ortholog of human FKTN (fukutin). WB:WBGene00021252 cht-4 Predicted to enable chitin binding activity and chitinase activity. Predicted to be involved in chitin catabolic process. Predicted to be located in extracellular region. WB:WBGene00021253 Y22D7AL.15 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00021254 Y22D7AL.16 Enriched in neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; pgl-1; and alg-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Zidovudine; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00021256 Y22D7AR.2 Predicted to be located in membrane. WB:WBGene00021257 Y22D7AR.3 Enriched in neurons and retrovesicular ganglion based on tiling array; single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by cadmium and Sirolimus based on microarray studies. WB:WBGene00021259 glb-30 Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00021260 Y22D7AR.6 Predicted to enable inositol hexakisphosphate kinase activity. Predicted to be involved in inositol phosphate biosynthetic process and phosphatidylinositol phosphate biosynthetic process. Predicted to be located in cytoplasm and nucleus. WB:WBGene00021261 Y22D7AR.7 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00021262 fbxa-74 Enriched in head mesodermal cell and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including Mercuric Chloride; rotenone; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00021263 spex-3 Enriched in AIM; arcade cell; germ line; intestine; and pharyngeal-intestinal valve cell based on proteomic; Chronogram; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-one chemicals including aldicarb; hydrogen sulfide; and Ethanol based on microarray and RNA-seq studies. WB:WBGene00021264 fbxa-13 Enriched in NSM; intestine; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including pgl-1; nhr-49; and aak-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; Alovudine; and tert-Butylhydroperoxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00021265 Y22D7AR.12 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; nicotinic acid; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00021266 Y22D7AR.14 Enriched in coelomocyte based on tiling array studies. Is affected by several genes including eat-2; pgl-1; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Tunicamycin; multi-walled carbon nanotube; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function and Domain of unknown function WSN. WB:WBGene00021267 Y23B4A.1 Enriched in mc2 and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eri-1; drh-3; and mir-34 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including aldicarb; hydrogen sulfide; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00021268 capa-1 Enables G protein-coupled receptor binding activity. Involved in neuropeptide signaling pathway. Expressed in ASGL and ASGR. WB:WBGene00021269 Y23H5A.2 Enriched in several structures, including ABplppaapa; ABprppaapa; command interneuron; germ line; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; dpy-10; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; mianserin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00021270 pid-3 Involved in piRNA processing; positive regulation of cell division; and positive regulation of chromosome segregation. Located in nucleus and perinuclear region of cytoplasm. WB:WBGene00021271 spe-47 Predicted to be located in cytoskeleton. WB:WBGene00021272 Y23H5B.1 Enriched in several structures, including ABalapppaa; ABalppappa; ADE sheath cell; head neurons; and nerve ring neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq studies. Is affected by nine chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq studies. WB:WBGene00021273 Y23H5B.2 Enriched in body wall muscle cell; hypodermis; neurons; and ventral nerve cord based on tiling array studies. Is affected by several genes including eat-2; pgl-1; and isp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00021274 Y23H5B.3 Enriched in amphid sheath cell and excretory system based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; aak-2; and bar-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00021275 dmsr-2 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in motor neurons. WB:WBGene00021276 Y23H5B.5 Predicted to be involved in positive regulation of transcription by RNA polymerase I and rRNA processing. Predicted to be located in nucleolus. Is an ortholog of human UTP15 (UTP15 small subunit processome component). WB:WBGene00021277 ddx-10 Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleus. Is an ortholog of human DDX10 (DEAD-box helicase 10). WB:WBGene00021278 Y23H5B.7 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and lin-35 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and metformin based on RNA-seq and microarray studies. WB:WBGene00021279 Y23H5B.8 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and ABarpppapa based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; methylmercuric chloride; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00021280 nspd-8 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray studies. Is affected by five chemicals including Tunicamycin; resveratrol; and Acrylamide based on microarray studies. Is predicted to encode a protein with the following domains: Caenorhabditis elegans protein of unknown function (DUF780) and Protein of unknown function DUF780, Caenorhabditis species. WB:WBGene00021281 ell-1 Predicted to enable cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription elongation by RNA polymerase II and snRNA transcription by RNA polymerase II. Located in nucleus. Expressed in hypodermis; intestine; pharynx; tail; and vulva. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 49. Is an ortholog of human ELL (elongation factor for RNA polymerase II) and MARVELD2 (MARVEL domain containing 2). WB:WBGene00021282 set-21 Expressed in hypodermis and somatic cell. Is predicted to encode a protein with the following domains: SET domain superfamily and SET domain. WB:WBGene00021284 Y24D9A.6 Predicted to be located in membrane. WB:WBGene00021285 Y24D9A.7 Predicted to be located in membrane. WB:WBGene00021286 tald-1 Predicted to enable transaldolase activity. Predicted to be involved in pentose-phosphate shunt, non-oxidative branch. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder. Is an ortholog of human TALDO1 (transaldolase 1). WB:WBGene00021287 Y24D9B.1 Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleus. Is an ortholog of human KHNYN (KH and NYN domain containing); N4BP1 (NEDD4 binding protein 1); and NYNRIN (NYN domain and retroviral integrase containing). WB:WBGene00021288 clec-123 Enriched in germ line and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-six chemicals including hydrogen sulfide; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00021289 Y25C1A.2 Enriched in AUA; cholinergic neurons; excretory cell; pharyngeal cell; and in male based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00021290 clec-122 Is affected by several genes including pmk-1; pgl-1; and glh-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin-like; T-complex protein 10, C-terminal domain superfamily; C-type lectin-like/link domain superfamily; Lectin C-type domain; and C-type lectin fold. WB:WBGene00021291 clec-121 Involved in IRE1-mediated unfolded protein response. WB:WBGene00021292 copb-1 Predicted to enable structural molecule activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intra-Golgi vesicle-mediated transport. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be part of COPI vesicle coat. Expressed in head and tail. Is an ortholog of human COPB1 (COPI coat complex subunit beta 1). WB:WBGene00021293 Y25C1A.6 Enriched in rect_D based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by seventeen chemicals including hydrogen sulfide; methylmercuric chloride; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00021294 Y25C1A.7 Predicted to enable small GTPase binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in Golgi apparatus. Is an ortholog of human YIPF1 (Yip1 domain family member 1) and YIPF2 (Yip1 domain family member 2). WB:WBGene00021295 Y25C1A.8 Predicted to enable lipopolysaccharide binding activity. Predicted to be involved in RNA processing. Predicted to be located in nucleus. Is an ortholog of human ZRANB2 (zinc finger RANBP2-type containing 2). WB:WBGene00021296 Y25C1A.13 Predicted to enable delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in mitochondrion. Is an ortholog of human ECH1 (enoyl-CoA hydratase 1). WB:WBGene00021297 fbxc-55 Is affected by several genes including elt-2; met-2; and hpl-2 based on tiling array and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00021298 Y27F2A.6 Predicted to be located in membrane. WB:WBGene00021299 Y27F2A.8 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppappa; ABalpppapa; and ciliated neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including hydrogen sulfide; mianserin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00021300 Y27F2A.9 Is affected by several genes including clk-1; aak-2; and bar-1 based on microarray and RNA-seq studies. Is affected by cholesterol based on RNA-seq studies. WB:WBGene00021301 Y32G9A.2 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00021302 Y32G9A.3 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; Doxycycline; and paraquat based on microarray and RNA-seq studies. WB:WBGene00021303 Y32G9A.5 Enriched in amphid sheath cell and neurons based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Chlorpyrifos based on microarray studies. WB:WBGene00021304 nphp-2 Involved in protein localization to ciliary inversin compartment. Located in ciliary inversin compartment. Expressed in neurons. Human ortholog(s) of this gene implicated in hypertension and nephronophthisis 2. Is an ortholog of human INVS (inversin). WB:WBGene00021305 zig-11 Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in axon and plasma membrane. Human ortholog(s) of this gene implicated in breast ductal carcinoma; carcinoma (multiple); and cervical cancer. Is an ortholog of human BSG (basigin (Ok blood group)) and NPTN (neuroplastin). WB:WBGene00021306 Y32G9A.9 No description available WB:WBGene00021309 Y32G9B.1 Predicted to be located in membrane. WB:WBGene00021310 Y32H12A.1 Predicted to be located in membrane. WB:WBGene00021311 thoc-5 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus and positive regulation of DNA-templated transcription, elongation. Predicted to be located in nucleus. Predicted to be part of THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in breast carcinoma. Is an ortholog of human THOC5 (THO complex subunit 5). WB:WBGene00021312 szy-2 Predicted to enable protein phosphatase inhibitor activity. Involved in several processes, including centrosome cycle; chromosome separation; and regulation of centrosome duplication. Is an ortholog of human PPP1R2 (protein phosphatase 1 regulatory inhibitor subunit 2) and PPP1R2B (PPP1R2 family member B). WB:WBGene00021313 paqr-2 Predicted to enable signaling receptor activity. Involved in positive regulation of fatty acid oxidation; response to cold; and tail spike morphogenesis. Located in plasma membrane. Expressed in gonadal sheath cell; head ganglion; head muscle; neurons; and seam cell. Human ortholog(s) of this gene implicated in several diseases, including non-alcoholic fatty liver disease; obesity; and type 2 diabetes mellitus. Is an ortholog of human ADIPOR1 (adiponectin receptor 1) and ADIPOR2 (adiponectin receptor 2). WB:WBGene00021314 Y32H12A.6 Predicted to enable 4 iron, 4 sulfur cluster binding activity and FMN binding activity. Predicted to be involved in tRNA processing. Predicted to be located in membrane. WB:WBGene00021315 Y32H12A.7 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Is an ortholog of human ADCK2 (aarF domain containing kinase 2). WB:WBGene00021316 Y32H12A.8 Predicted to be involved in rRNA processing. Predicted to be located in nucleus. Expressed in head and tail. Is an ortholog of human WDR24 (WD repeat domain 24). WB:WBGene00021317 Y32H12A.9 Is affected by several genes including daf-16; daf-12; and clk-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00021319 Y34B4A.2 Predicted to enable SNARE binding activity. Predicted to be involved in SNARE complex assembly. Predicted to be located in endosome and lytic vacuole. Is an ortholog of human UVRAG (UV radiation resistance associated). WB:WBGene00021320 Y34B4A.4 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to be located in plasma membrane. Is an ortholog of human RAPGEF1 (Rap guanine nucleotide exchange factor 1). WB:WBGene00021321 nspg-12 Enriched in OLL; PVD; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including manganese chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021322 nspg-14 Enriched in germ line; head mesodermal cell; intestine; mechanosensory neurons; and pharyngeal muscle cell based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including methylmercuric chloride; rotenone; and D-glucopyranose based on microarray and RNA-seq studies. WB:WBGene00021323 Y34B4A.7 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00021324 rga-8 Predicted to enable GTPase activator activity. Predicted to be involved in regulation of Rac protein signal transduction and regulation of actin cytoskeleton organization. Is an ortholog of human ARHGAP17 (Rho GTPase activating protein 17); ARHGAP44 (Rho GTPase activating protein 44); and SH3BP1 (SH3 domain binding protein 1). WB:WBGene00021325 nspg-13 Enriched in AFD; head mesodermal cell; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00021326 Y34B4A.10 Enriched in germline precursor cell; hypodermis; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; Ethanol; and methylmercury hydroxide based on microarray and RNA-seq studies. WB:WBGene00021327 mrpl-38 Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Expressed in tail. Is an ortholog of human MRPL38 (mitochondrial ribosomal protein L38). WB:WBGene00021328 npr-23 Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection. WB:WBGene00021329 Y34D9A.3 Enriched in several structures, including ABplapaaaap; ABplapaaapa; ABplpaaaaa; ABprapaaaap; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; npr-1; and sek-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00021331 glrx-10 Predicted to enable glutathione disulfide oxidoreductase activity. Used to study Parkinson's disease. Is an ortholog of human GLRX (glutaredoxin). WB:WBGene00021332 Y34D9A.7 Predicted to enable RNA binding activity. Predicted to be involved in ncRNA processing. Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human ZCCHC8 (zinc finger CCHC-type containing 8). WB:WBGene00021333 Y34D9A.8 Predicted to be located in membrane. WB:WBGene00021334 vps-4 Predicted to enable ATP binding activity and ATP hydrolysis activity. Involved in mechanosensory behavior and protein localization to postsynaptic membrane. Predicted to be located in endosome membrane. Is an ortholog of human VPS4A (vacuolar protein sorting 4 homolog A) and VPS4B (vacuolar protein sorting 4 homolog B). WB:WBGene00021335 spp-23 Enriched in DA neuron; VA neuron; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; tiling array; and microarray studies. Is affected by twenty-two chemicals including rotenone; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. WB:WBGene00021336 Y34F4.1 Predicted to be located in membrane. WB:WBGene00021337 Y34F4.2 Predicted to be located in membrane. WB:WBGene00021338 Y34F4.3 Enriched in AFD and AVA based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; fog-2; and dcr-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Tunicamycin; paraquat; and Atrazine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PAP/25A-associated and Cid1 family poly A polymerase. WB:WBGene00021339 Y34F4.4 Predicted to be located in membrane. WB:WBGene00021340 Y34F4.5 Predicted to be located in membrane. WB:WBGene00021342 Y35H6.3 Enriched in coelomocyte; germ line; germline precursor cell; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including hsf-1; clk-1; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including rotenone; D-glucose; and Psoralens based on RNA-seq studies. WB:WBGene00021343 cutl-23 Enriched in several structures, including AVK; accessory cell; head neurons; sensory neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; Tunicamycin; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: von Willebrand factor, type A; von Willebrand factor type A domain; Zona pellucida, ZP-C domain; von Willebrand factor A-like domain superfamily; Zona pellucida-like domain; and Zona pellucida domain. WB:WBGene00021344 rev-3 Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in double-strand break repair via homologous recombination and error-prone translesion synthesis. Predicted to be located in nucleus. Predicted to be part of zeta DNA polymerase complex. Is an ortholog of human REV3L (REV3 like, DNA directed polymerase zeta catalytic subunit). WB:WBGene00021345 Y37B11A.3 Predicted to enable citrate secondary active transmembrane transporter activity. Predicted to be involved in mitochondrial citrate transmembrane transport. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined D-2- and L-2-hydroxyglutaric aciduria and congenital myasthenic syndrome. Is an ortholog of human SLC25A1 (solute carrier family 25 member 1). WB:WBGene00021346 Y37E3.1 Enriched in several structures, including ABalpppappp; ABalpppppa; ABalppppppp; ciliated neurons; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including hsf-1; hpl-2; and dpy-9 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including rotenone; paraquat; and Atrazine based on RNA-seq and microarray studies. Human TTC5 enables ribosome binding activity. Is predicted to encode a protein with the following domains: Tetratricopeptide repeat protein 5 OB fold domain; Tetratricopeptide repeat; Tetratricopeptide-like helical domain superfamily; Tetratricopeptide repeat protein 5, OB fold domain; and TTC5, OB fold domain superfamily. Is an ortholog of human TTC5 (tetratricopeptide repeat domain 5). WB:WBGene00021347 rpb-10 Predicted to enable zinc ion binding activity. Predicted to contribute to RNA polymerase I activity; RNA polymerase II activity; and RNA polymerase III activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase I; and transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Is an ortholog of human POLR2L (RNA polymerase II, I and III subunit L). WB:WBGene00021348 moag-4 Involved in protein destabilization. Located in cytosol and nucleus. Is an ortholog of human SERF2 (small EDRK-rich factor 2). WB:WBGene00021349 arl-13 Predicted to enable GTP binding activity and GTPase activity. Involved in cilium organization; receptor localization to non-motile cilium; and sensory perception of chemical stimulus. Acts upstream of or within motile cilium assembly. Located in plasma membrane bounded cell projection. Expressed in ciliated neurons and head. Used to study Joubert syndrome. Human ortholog(s) of this gene implicated in Joubert syndrome 8. Is an ortholog of human ARL13B (ADP ribosylation factor like GTPase 13B). WB:WBGene00021350 Y37E3.8 Predicted to be a structural constituent of ribosome. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in somatic cell. Is an ortholog of human RPL27A (ribosomal protein L27a). WB:WBGene00021351 eif-2alpha Predicted to enable ribosome binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic 48S preinitiation complex and eukaryotic translation initiation factor 2 complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha). WB:WBGene00021352 pcyt-2.1 Predicted to enable ethanolamine-phosphate cytidylyltransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 82. Is an ortholog of human PCYT2 (phosphate cytidylyltransferase 2, ethanolamine). WB:WBGene00021353 iglr-3 Predicted to be located in membrane. Is an ortholog of human LRRC24 (leucine rich repeat containing 24). WB:WBGene00021354 fpn-1.1 Predicted to enable iron ion transmembrane transporter activity. Predicted to be involved in iron ion transmembrane transport. Predicted to be located in basolateral plasma membrane and lateral plasma membrane. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Is an ortholog of human SLC40A1 (solute carrier family 40 member 1). WB:WBGene00021355 Y37E3.17 Predicted to enable dimethylglycine dehydrogenase activity. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human DMGDH (dimethylglycine dehydrogenase). WB:WBGene00021356 Y37E3.18 No description available WB:WBGene00021357 Y37E11AL.1 Predicted to be located in membrane. WB:WBGene00021358 Y37E11AL.2 Predicted to be located in membrane. WB:WBGene00021359 Y37E11AL.3 Enriched in several structures, including ABalappaap; ABalapppaa; ABplapppaa; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021360 Y37E11AL.4 Enriched in AVE; BAG; dopaminergic neurons; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; aak-2; and hsp-6 based on microarray and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; Doxycycline; and paraquat based on microarray and RNA-seq studies. WB:WBGene00021362 fmil-1 Predicted to enable calcium ion binding activity. Predicted to be located in membrane. WB:WBGene00021363 taf-6.2 Predicted to enable transcription coactivator activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Is an ortholog of human TAF6 (TATA-box binding protein associated factor 6). WB:WBGene00021364 Y37E11AL.9 Is affected by several genes including daf-2; daf-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00021365 smgl-2 Predicted to enable RNA binding activity and helicase activity. Involved in nuclear-transcribed mRNA catabolic process. Is an ortholog of human DHX34 (DExH-box helicase 34). WB:WBGene00021366 Y37E11AM.2 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalapapap; PVR; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including age-1; hsf-1; and egl-5 based on microarray and RNA-seq studies. Is affected by six chemicals including stavudine; Zidovudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021367 Y37E11AM.3 Predicted to enable 3-dehydrosphinganine reductase activity. Predicted to be involved in 3-keto-sphinganine metabolic process and sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 4 and follicular lymphoma. Is an ortholog of human KDSR (3-ketodihydrosphingosine reductase). WB:WBGene00021368 best-20 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00021369 siah-1 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Involved in programmed cell death involved in cell development. Predicted to be located in cytoplasm. Expressed in AIYL; AIYR; and tail. Is an ortholog of human SIAH1 (siah E3 ubiquitin protein ligase 1). WB:WBGene00021370 nape-2 Enables N-acylphosphatidylethanolamine-specific phospholipase D activity. Involved in N-acylethanolamine metabolic process. Located in neuron projection. Expressed in pharynx; somatic nervous system; spermatheca; and vulval muscle. WB:WBGene00021371 nape-1 Enables N-acylphosphatidylethanolamine-specific phospholipase D activity. Involved in N-acylethanolamine metabolic process. Located in neuronal cell body. Expressed in nervous system; pharynx; and vulval muscle. Is an ortholog of human NAPEPLD (N-acyl phosphatidylethanolamine phospholipase D). WB:WBGene00021372 ugt-45 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00021373 Y37E11AR.7 Predicted to be located in membrane. Is an ortholog of human FAM187B (family with sequence similarity 187 member B). WB:WBGene00021374 Y37E11B.1 Predicted to enable chromatin insulator sequence binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome. WB:WBGene00021375 Y37E11B.2 Enriched in several structures, including arc ant V; cephalic sheath cell; enteric muscle; rectal muscle; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including let-60; rrf-3; and hsf-1 based on RNA-seq and microarray studies. Is affected by antimycin; paraquat; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021376 blos-7 Predicted to be involved in lysosome localization. Predicted to be part of BORC complex. Is an ortholog of human BORCS6 (BLOC-1 related complex subunit 6). WB:WBGene00021377 Y37E11B.5 Predicted to enable tRNA dihydrouridine synthase activity. Predicted to be involved in tRNA dihydrouridine synthesis. Is an ortholog of human DUS3L (dihydrouridine synthase 3 like). WB:WBGene00021378 Y37E11B.6 Predicted to be involved in tRNA processing. Predicted to be part of nucleolar ribonuclease P complex. WB:WBGene00021379 Y37E11B.7 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00021380 Y37E11B.9 Is affected by several genes including daf-2; sir-2.1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including methylmercury hydroxide; methylmercuric chloride; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00021381 Y37E11B.10 Enriched in MC neuron; MCL; MCR; germ line; and in male based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including hydrogen sulfide; Ethanol; and methylmercury hydroxide based on microarray; RNA-seq; and proteomic studies. WB:WBGene00021382 Y37F4.1 Enriched in neurons and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including D-glucose; Sodium Chloride; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily. WB:WBGene00021383 Y37F4.2 Enriched in AWC and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including age-1; clk-1; and rsr-2 based on microarray; tiling array; and RNA-seq studies. WB:WBGene00021384 Y37F4.3 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array and RNA-seq studies. Is affected by allantoin; Sirolimus; and metformin based on RNA-seq studies. WB:WBGene00021385 Y37F4.4 Enriched in NSM and body wall muscle cell based on tiling array studies. Is affected by ain-1 based on microarray studies. WB:WBGene00021386 Y37F4.5 Predicted to be located in membrane. WB:WBGene00021387 Y37F4.6 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. WB:WBGene00021388 Y37F4.7 Predicted to be located in membrane. WB:WBGene00021389 Y38A10A.2 Enriched in several structures, including arc ant V; excretory system; sensory neurons; somatic gonad precursor; and tail hypodermis based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including Ethanol; tryptophan; and methylmercury hydroxide based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF229) and Protein of unknown function DUF229. WB:WBGene00021390 fbxa-214 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00021391 smut-1 Predicted to enable ATP binding activity and nucleic acid binding activity. Expressed in embryonic cell and germ cell. WB:WBGene00021392 Y38A10A.7 Predicted to enable histone H2A acetyltransferase activity; histone H4 acetyltransferase activity; and peptide-serine-alpha-N-acetyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus. Is an ortholog of human NAA40 (N-alpha-acetyltransferase 40, NatD catalytic subunit). WB:WBGene00021394 Y38C1AA.1 Predicted to enable acyltransferase activity. Predicted to be located in membrane. Is an ortholog of human TMEM68 (transmembrane protein 68). WB:WBGene00021395 pnc-1 Enables nicotinamidase activity. Involved in nicotinamide metabolic process. Located in cytoplasm; extracellular space; and nucleus. Expressed in several structures, including coelomocyte; epithelial cell; head ganglion; lumbar neurons; and pharyngeal cell. WB:WBGene00021396 cutl-24 Predicted to be located in membrane. WB:WBGene00021397 Y38C1AA.6 Predicted to enable metal ion binding activity. WB:WBGene00021398 Y38C1AA.7 Predicted to be located in membrane. WB:WBGene00021400 gegf-1 Enriched in ABplpppppp; ABprpppppp; neuronal sheath cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: EGF-like domain and Phosphorylation site. WB:WBGene00021401 prdx-6 Predicted to enable peroxiredoxin activity. Predicted to be involved in cell redox homeostasis. Predicted to be located in cytosol and mitochondrion. Is an ortholog of human PRDX6 (peroxiredoxin 6). WB:WBGene00021402 Y38C1AA.12 Enriched in several structures, including ABplapaaap; AVK; PLM; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; npr-1; and sma-4 based on RNA-seq and microarray studies. Is affected by eight chemicals including rotenone; Zidovudine; and metformin based on RNA-seq studies. WB:WBGene00021403 Y38C1AB.1 Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human C1GALT1C1L (C1GALT1 specific chaperone 1 like). WB:WBGene00021404 trpl-3 Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in membrane. WB:WBGene00021405 Y38C1AB.3 Is affected by several genes including daf-16; clk-1; and isp-1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by four chemicals including Rifampin; atracurium; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00021406 frm-5.2 Enriched in OLL; PVD; head mesodermal cell; and sensory neurons based on microarray and RNA-seq studies. Is affected by several genes including daf-16; let-60; and let-7 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by ten chemicals including metformin; Sirolimus; and silicon dioxide nanoparticle based on RNA-seq; microarray; and proteomic studies. Human FRMPD2 enables 1-phosphatidylinositol binding activity. Is predicted to encode a protein with the following domains: FERM/acyl-CoA-binding protein superfamily; Ubiquitin-like domain superfamily; FERM superfamily, second domain; PH-like domain superfamily; FERM C-terminal PH-like domain; FERM, N-terminal; PDZ superfamily; FERM, C-terminal PH-like domain; FERM N-terminal domain; Band 4.1 domain; PDZ domain; and FERM central domain. Is an ortholog of human FRMPD2 (FERM and PDZ domain containing 2). WB:WBGene00021407 Y38C1AB.5 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human C1GALT1C1L (C1GALT1 specific chaperone 1 like). WB:WBGene00021408 trpl-4 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and daf-18 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00021409 Y38C1AB.7 Is affected by several genes including daf-16; clk-1; and isp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by Rifampin based on RNA-seq studies. WB:WBGene00021410 Y38C1BA.1 Predicted to be located in membrane. WB:WBGene00021412 cyp-29A3 Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in Bietti crystalline corneoretinal dystrophy. Is an ortholog of human CYP4V2 (cytochrome P450 family 4 subfamily V member 2). WB:WBGene00021413 srt-52 Predicted to be located in membrane. WB:WBGene00021414 Y38C9B.3 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and tiling array studies. Is affected by Chlorpyrifos and Diazinon based on microarray studies. WB:WBGene00021415 nsy-4 Enables calcium channel inhibitor activity and protein kinase inhibitor activity. Involved in determination of left/right asymmetry in nervous system. Located in plasma membrane and plasma membrane bounded cell projection. Expressed in anterior hypodermis; blast cell; excretory cell; neurons; and tail hypodermis. WB:WBGene00021416 mksr-2 Involved in several processes, including determination of adult lifespan; larval foraging behavior; and non-motile cilium assembly. Located in ciliary basal body; ciliary transition zone; and dendrite terminus. Expressed in neurons. Used to study Joubert syndrome. Human ortholog(s) of this gene implicated in Joubert syndrome. Is an ortholog of human B9D2 (B9 domain containing 2). WB:WBGene00021417 nhr-236 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00021418 Y38F2AL.6 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00021419 eri-5 Enables enzyme binding activity and protein-macromolecule adaptor activity. Involved in siRNA processing. WB:WBGene00021420 trap-3 Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in endoplasmic reticulum. Is an ortholog of human SSR3 (signal sequence receptor subunit 3). WB:WBGene00021421 Y38F2AR.3 Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 31. Is an ortholog of human TIMMDC1 (translocase of inner mitochondrial membrane domain containing 1). WB:WBGene00021422 Y38F2AR.4 No description available WB:WBGene00021423 tftc-1 Predicted to enable DNA binding activity. Predicted to be involved in 5S class rRNA transcription by RNA polymerase III and transcription initiation at RNA polymerase III promoter. Predicted to be part of transcription factor TFIIIC complex. Is an ortholog of human GTF3C1 (general transcription factor IIIC subunit 1). WB:WBGene00021425 ppgn-1 Predicted to enable metalloendopeptidase activity. Predicted to be involved in mitochondrial protein processing. Predicted to be located in membrane. Predicted to be part of m-AAA complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 7. Is an ortholog of human SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin). WB:WBGene00021427 sec-61.B Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation and post-translational protein targeting to membrane, translocation. Predicted to be located in membrane. Predicted to be part of Sec61 translocon complex. Is an ortholog of human SEC61B (SEC61 translocon subunit beta). WB:WBGene00021428 Y38F2AR.10 Predicted to enable FFAT motif binding activity. Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum-plasma membrane tethering. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. WB:WBGene00021430 Y38F2AR.12 Predicted to enable 5-oxoprolinase (ATP-hydrolyzing) activity. Predicted to be involved in glutathione metabolic process. Is an ortholog of human OPLAH (5-oxoprolinase, ATP-hydrolysing). WB:WBGene00021432 Y39A3A.1 No description available WB:WBGene00021433 Y39A3A.2 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; alg-1; and drh-3 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00021434 Y39A3A.3 Enriched in ABplpppaapa; ABprpppaapa; cephalic sheath cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Mercuric Chloride; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Vitelline membrane outer layer protein I (VOMI) superfamily. WB:WBGene00021435 Y39A3A.4 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in motor neuron axon guidance. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Is an ortholog of human PTPRG (protein tyrosine phosphatase receptor type G) and PTPRZ1 (protein tyrosine phosphatase receptor type Z1). WB:WBGene00021436 Y39A3B.1 Predicted to enable metalloexopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00021437 lgc-42 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in hyperekplexia 1; hyperekplexia 2; and syndromic X-linked intellectual disability Pilgorge type. Is an ortholog of several human genes including GLRA1 (glycine receptor alpha 1); GLRA2 (glycine receptor alpha 2); and GLRB (glycine receptor beta). WB:WBGene00021438 Y39A3B.3 Enriched in g1P and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; csr-1; and smg-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00021439 ckr-2 Enables neuropeptide binding activity. Involved in determination of adult lifespan and neuropeptide signaling pathway. Predicted to be located in plasma membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in several diseases, including cholelithiasis; pancreatic ductal carcinoma; and panic disorder. Is an ortholog of human CCKAR (cholecystokinin A receptor). WB:WBGene00021440 Y39A3CL.1 Enriched in several structures, including I5 neuron; cholinergic neurons; germ line; germline precursor cell; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including dpy-10; hsf-1; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00021441 Y39A3CL.3 Predicted to be located in membrane. WB:WBGene00021442 Y39A3CL.4 Enriched in excretory cell; germ line; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; sir-2.1; and sek-1 based on RNA-seq; microarray; and proteomic studies. Is affected by eight chemicals including aldicarb; Zidovudine; and paraquat based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: TLD and TLDc domain. WB:WBGene00021443 Y39A3CL.7 Enriched in ABalappaap and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including stavudine; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021444 ttc-7 Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in multiple intestinal atresia. Is an ortholog of human TTC7A (tetratricopeptide repeat domain 7A) and TTC7B (tetratricopeptide repeat domain 7B). WB:WBGene00021446 hlh-33 Predicted to enable protein dimerization activity. WB:WBGene00021448 Y39D8A.1 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00021449 mltn-7 Predicted to be located in membrane. WB:WBGene00021450 mltn-6 Predicted to be located in membrane. WB:WBGene00021451 mltn-8 Predicted to be located in membrane. WB:WBGene00021452 Y39F10A.1 Enriched in muscle cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; let-7; and gld-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00021453 Y39F10A.2 Is affected by several genes including age-1; rrf-3; and mut-2 based on microarray and tiling array studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00021454 Y39F10A.3 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00021455 Y39F10A.4 No description available WB:WBGene00021456 rfip-2 Predicted to enable small GTPase binding activity. Predicted to be involved in regulated exocytosis. Predicted to be located in intracellular membrane-bounded organelle. Is an ortholog of human RAB11FIP1 (RAB11 family interacting protein 1) and RAB11FIP5 (RAB11 family interacting protein 5). WB:WBGene00021457 Y39F10C.1 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00021458 Y39G10AL.1 Enriched in several structures, including ABplppppap; ABprppppap; AVK; MC neuron; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; Mercuric Chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00021460 zwl-1 Involved in positive regulation of mitotic spindle pole body separation; positive regulation of protein localization to kinetochore; and protein localization to kinetochore involved in kinetochore assembly. Located in kinetochore. Part of RZZ complex. Is an ortholog of human ZWILCH (zwilch kinetochore protein). WB:WBGene00021461 nekl-1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in nucleus. Expressed in amphid neurons and lumbar neurons. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome; nephronophthisis 9; and renal-hepatic-pancreatic dysplasia. Is an ortholog of human NEK9 (NIMA related kinase 9). WB:WBGene00021463 zeel-1 Predicted to be located in membrane. Predicted to be part of Cul2-RING ubiquitin ligase complex. Expressed in embryonic cell. WB:WBGene00021464 ugt-31 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00021465 ekl-7 Enriched in several structures, including ABplpppppp; ABprpppppp; Caapa; germ line; and head mesodermal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including glp-1; dpy-10; and eat-2 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including methylmercuric chloride; Alovudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00021466 eif-2gamma Predicted to enable translation initiation factor activity. Predicted to contribute to tRNA binding activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to be part of eukaryotic translation initiation factor 2 complex. Expressed in tail. Human ortholog(s) of this gene implicated in MEHMO syndrome. Is an ortholog of human EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma) and EIF2S3B (eukaryotic translation initiation factor 2 subunit gamma B). WB:WBGene00021467 Y39G10AR.9 Enriched in several structures, including ABalpppappp; ABplpaaaaa; ABpraaaappp; ABprpaaaaa; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including age-1; hsf-1; and gld-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by eight chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: WD40 repeat; WD40/YVTN repeat-like-containing domain superfamily; WD40-repeat-containing domain superfamily; and WD domain, G-beta repeat. Is an ortholog of human PAAF1 (proteasomal ATPase associated factor 1). WB:WBGene00021468 epg-2 Involved in macroautophagy and negative regulation of autophagosome assembly. Located in cytoplasm. WB:WBGene00021469 Y39G10AR.11 Enriched in ABplpaapap; ABprpaapap; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; rotenone; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00021470 tpxl-1 Enables protein kinase binding activity. Involved in astral microtubule organization and mitotic spindle assembly. Located in astral microtubule; meiotic spindle; and spindle pole centrosome. WB:WBGene00021471 Y39G10AR.15 Enriched in ABalppppapa; ABpraaapapa; AVH; MC neuron; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00021472 Y39G10AR.16 Predicted to be located in membrane. WB:WBGene00021473 sydn-1 Predicted to be involved in mRNA processing. Located in nuclear speck. Expressed in germ cell; hypodermis; neurons; and oocyte. WB:WBGene00021474 dot-1.1 Predicted to enable histone H3K79 methyltransferase activity. Predicted to be involved in DNA damage checkpoint signaling and DNA repair. Predicted to be located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in acute biphenotypic leukemia. Is an ortholog of human DOT1L (DOT1 like histone lysine methyltransferase). WB:WBGene00021475 tbca-1 Predicted to enable tubulin binding activity. Predicted to be involved in protein folding and tubulin complex assembly. Predicted to be located in microtubule cytoskeleton. Is an ortholog of human TBCA (tubulin folding cofactor A). WB:WBGene00021476 nsun-4 Enables rRNA (cytosine-C5-)-methyltransferase activity and tRNA (cytosine-5-)-methyltransferase activity. Predicted to be involved in rRNA methylation and tRNA methylation. Predicted to be located in mitochondrion. Is an ortholog of human NSUN4 (NOP2/Sun RNA methyltransferase 4). WB:WBGene00021477 srbc-64 Enables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway and dauer larval development. Located in non-motile cilium and periciliary membrane compartment. Expressed in ASKL and ASKR. WB:WBGene00021478 Y39H10A.1 Enriched in amphid sheath cell; arcade cell; neurons; and pharyngeal-intestinal valve cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Mercuric Chloride; multi-walled carbon nanotube; and indole based on microarray and RNA-seq studies. WB:WBGene00021479 oac-55 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00021482 gid-7 Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of GID complex. Is an ortholog of human WDR26 (WD repeat domain 26). WB:WBGene00021483 Y40A1A.1 Enriched in Z1 and Z4 based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00021484 Y40A1A.2 Enriched in ABalapppaa; ABplpappaa; and Caapa based on single-cell RNA-seq studies. Is affected by several genes including age-1; eat-2; and mex-3 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00021485 Y40A1A.3 Enriched in several structures, including ABalapppaa; ABplpppaapa; ABprpppaapa; accessory cell; and head mesodermal cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including clk-1; sek-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including tryptophan; D-glucose; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00021486 lbp-9 Predicted to enable fatty acid binding activity. Predicted to be involved in fatty acid transport. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in pre-eclampsia. Is an ortholog of human FABP4 (fatty acid binding protein 4). WB:WBGene00021487 comt-3 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human COMTD1 (catechol-O-methyltransferase domain containing 1). WB:WBGene00021488 srab-23 Predicted to be located in membrane. WB:WBGene00021489 Y40B10A.4 Enriched in intestine and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00021490 Y40B10A.5 Predicted to be located in membrane. WB:WBGene00021491 comt-4 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human COMTD1 (catechol-O-methyltransferase domain containing 1). WB:WBGene00021492 comt-5 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human COMTD1 (catechol-O-methyltransferase domain containing 1). WB:WBGene00021493 Y40B10A.9 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Predicted to be located in membrane. Expressed in body wall musculature. WB:WBGene00021494 Y40B10B.1 Predicted to be located in extracellular space. Is an ortholog of human VMO1 (vitelline membrane outer layer 1 homolog). WB:WBGene00021495 sqst-2 Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and protein kinase C binding activity. Predicted to be involved in aggrephagy; endosome organization; and mitophagy. Predicted to be located in aggresome and amphisome. WB:WBGene00021496 daf-42 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapapapa; ABalapappaa; and anterior ganglion (post) based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by four chemicals including Zidovudine; sucrose; and stearic acid based on RNA-seq and microarray studies. WB:WBGene00021497 Y40C5A.4 Predicted to enable phosphoric diester hydrolase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in membrane. Expressed in AIYL and AIYR. WB:WBGene00021498 Y40C7B.1 No description available WB:WBGene00021499 Y40C7B.3 No description available WB:WBGene00021500 Y40C7B.4 Enriched in coelomocyte; intestine; mechanosensory neurons; and pharyngeal muscle cell based on tiling array and microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including Tunicamycin; D-glucopyranose; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00021501 Y40C7B.5 No description available WB:WBGene00021502 cmtr-2 Predicted to enable mRNA (nucleoside-2'-O-)-methyltransferase activity. Predicted to be involved in 7-methylguanosine mRNA capping; cap1 mRNA methylation; and cap2 mRNA methylation. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human CMTR2 (cap methyltransferase 2). WB:WBGene00021503 ctsa-4.2 Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. Human ortholog(s) of this gene implicated in galactosialidosis. Is an ortholog of human CTSA (cathepsin A). WB:WBGene00021504 Y41D4A.1 Enriched in pharyngeal gland cell and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including elt-2; pmk-1; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; allantoin; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Cysteine-rich repeat. WB:WBGene00021505 Y41D4A.3 Enriched in several structures, including ABalaapppa; ABalapaaaa; GABAergic neurons; accessory cell; and ciliated neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021506 Y41D4A.4 Predicted to be involved in protein localization to membrane. Predicted to be located in membrane. Expressed in head and tail. Is an ortholog of human TM9SF3 (transmembrane 9 superfamily member 3). WB:WBGene00021507 ptpn-22 Predicted to enable protein tyrosine phosphatase activity. Human ortholog(s) of this gene implicated in several diseases, including Addison's disease; autoimmune disease (multiple); and graft-versus-host disease. Is an ortholog of human PTPN22 (protein tyrosine phosphatase non-receptor type 22). WB:WBGene00021508 Y41D4A.6 Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be part of glutamyl-tRNA(Gln) amidotransferase complex. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 40. Is an ortholog of human QRSL1 (glutaminyl-tRNA amidotransferase subunit QRSL1). WB:WBGene00021509 Y41D4A.7 Enriched in body wall muscle cell; head mesodermal cell; neurons; and rectal epithelium based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and sir-2.1 based on RNA-seq; tiling array; and microarray studies. Is affected by Rifampin; paraquat; and nitroguanidine based on RNA-seq and microarray studies. WB:WBGene00021510 frpr-19 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00021511 Y41D4B.1 Predicted to be located in membrane. WB:WBGene00021512 Y41D4B.4 Predicted to be involved in cell division. WB:WBGene00021513 Y41D4B.6 Predicted to enable Notch binding activity. Predicted to be involved in cell fate specification. WB:WBGene00021514 Y41D4B.11 Predicted to be located in nucleus. WB:WBGene00021515 set-23 Predicted to enable double-stranded DNA binding activity and histone methyltransferase activity. Predicted to be involved in chromatin remodeling and methylation. Predicted to be located in chromosome and nucleus. Expressed in hypodermis. Is an ortholog of human SETMAR (SET domain and mariner transposase fusion gene). WB:WBGene00021516 Y41D4B.14 Enriched in intestine; tail precursor cell; and terminal bulb based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies. WB:WBGene00021517 Y41D4B.15 Enriched in Z1.p; Z4.a; intestine; male distal tip cell; and mechanosensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including tryptophan; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00021518 hpo-6 Located in membrane raft. WB:WBGene00021519 Y41D4B.17 Enriched in several structures, including ABalppappa; ABarappppa; intestine; male distal tip cell; and mechanosensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including methylmercuric chloride; mianserin; and D-glucopyranose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00021520 Y41D4B.18 Enriched in OLL; PVD; and intestine based on microarray and tiling array studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including aldicarb; tryptophan; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00021521 nhr-287 Enriched in ABalpapaap; ABarappaap; AFD; excretory cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021522 nhr-274 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00021524 Y41D4B.24 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00021525 cpg-24 Predicted to enable Notch binding activity. Predicted to be involved in cell fate specification. WB:WBGene00021526 nspg-5 Predicted to be located in membrane. WB:WBGene00021527 aakg-3 Predicted to enable AMP binding activity; protein kinase binding activity; and protein kinase regulator activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleotide-activated protein kinase complex. Expressed in alimentary muscle; body wall musculature; head neurons; spermatheca; and ventral nerve cord. Human ortholog(s) of this gene implicated in Wolff-Parkinson-White syndrome; hypertrophic cardiomyopathy 6; and lethal congenital glycogen storage disease of heart. Is an ortholog of human PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1); PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2); and PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3). WB:WBGene00021528 gbb-1 Enables G protein-coupled GABA receptor activity. Involved in G protein-coupled receptor signaling pathway; negative regulation of cholinergic synaptic transmission; and response to xenobiotic stimulus. Predicted to be located in plasma membrane. Predicted to be part of G protein-coupled receptor heterodimeric complex. Expressed in nervous system. Is an ortholog of human GABBR1 (gamma-aminobutyric acid type B receptor subunit 1). WB:WBGene00021529 Y41G9A.5 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; interfacial epithelial cell; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including methylmercury hydroxide; manganese chloride; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021530 Y41G9A.6 Enriched in AVAL; AVAR; DVC; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-12; eat-2; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Diazinon based on microarray studies. WB:WBGene00021531 Y42G9A.1 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; head mesodermal cell; and mechanosensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Cry5B; paraquat; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021532 Y42G9A.2 Enriched in PLM and interfacial epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021533 Y42G9A.3 Predicted to be involved in signal transduction. Is an ortholog of human LRRC58 (leucine rich repeat containing 58). WB:WBGene00021534 mvk-1 Predicted to enable mevalonate kinase activity. Predicted to be involved in cholesterol biosynthetic process and isopentenyl diphosphate biosynthetic process, mevalonate pathway. Located in cytosol. Expressed in head. Human ortholog(s) of this gene implicated in lipid metabolism disorder; mevalonic aciduria; and porokeratosis. Is an ortholog of human MVK (mevalonate kinase). WB:WBGene00021535 wht-7 Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. WB:WBGene00021536 Y42H9AR.1 Predicted to be involved in Golgi organization. Predicted to be located in Golgi apparatus. Is an ortholog of human GORASP2 (golgi reassembly stacking protein 2). WB:WBGene00021537 Y42H9AR.2 Predicted to be involved in negative regulation of apoptotic signaling pathway. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Is an ortholog of human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1) and TMBIM1 (transmembrane BAX inhibitor motif containing 1). WB:WBGene00021538 rabs-5 Predicted to enable phosphatidylinositol-3-phosphate binding activity. Involved in pinocytosis and receptor-mediated endocytosis. Expressed in PQR; amphid neurons; phasmid neurons; and ray neurons. Is an ortholog of human RBSN (rabenosyn, RAB effector). WB:WBGene00021539 Y42H9AR.4 Enriched in ABplppaaaap; ABprppaaaap; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including D-glucose; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021540 Y42H9AR.5 Enriched in several structures, including BDU; germline precursor cell; intestine; neurons; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00021541 Y42H9B.3 Enriched in GLR; body wall muscle cell; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00021542 Y43B11AL.1 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalaapppa; ABalapaaaa; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; bisphenol S; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021543 Y43B11AR.1 Enriched in several structures, including ABarppaapp; ABarpppapp; excretory cell; neuronal sheath cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by seventeen chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00021544 Y43B11AR.3 Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Is an ortholog of human TRUB2 (TruB pseudouridine synthase family member 2). WB:WBGene00021545 Y43H11AL.1 Predicted to enable methylated histone binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. WB:WBGene00021546 laat-1 Enables L-arginine transmembrane transporter activity and L-lysine transmembrane transporter activity. Involved in basic amino acid transport; intracellular amino acid homeostasis; and positive regulation of autophagy. Located in lysosomal membrane. Used to study lysosomal storage disease. Is an ortholog of human SLC66A1 (solute carrier family 66 member 1). WB:WBGene00021547 Y44E3A.1 Predicted to enable hydrolase activity. WB:WBGene00021548 trx-4 Predicted to enable protein-disulfide reductase activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in cardiomyopathy (multiple) and coronary artery disease (multiple). Is an ortholog of human TXN (thioredoxin). WB:WBGene00021549 cdap-2 Predicted to be involved in actin filament organization and cell migration. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 3 and immunodeficiency 61. Is an ortholog of human CD2AP (CD2 associated protein). WB:WBGene00021551 edc-4 Predicted to be involved in deadenylation-independent decapping of nuclear-transcribed mRNA. Predicted to be located in P-body. Is an ortholog of human EDC4 (enhancer of mRNA decapping 4). WB:WBGene00021552 zip-4 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in nucleus. Expressed in gonad; pharynx; spermatheca; and vulva. WB:WBGene00021553 tyr-5 Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human TYR (tyrosinase). WB:WBGene00021554 Y45G5AL.1 Enriched in germ line; intestinal muscle; neurons; and rectal muscle based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; hsf-1; and pgl-1 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by seven chemicals including rotenone; Cry5B; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021555 pid-5 Predicted to enable aminopeptidase activity. Predicted to be involved in regulatory ncRNA-mediated gene silencing. Predicted to be located in P-body and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in acquired angioedema. Is an ortholog of human XPNPEP1 (X-prolyl aminopeptidase 1). WB:WBGene00021556 Y45G5AM.3 Enriched in amphid sheath cell and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; stavudine; and Sodium Chloride based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: F-box protein she-1-like. WB:WBGene00021557 Y45G5AM.5 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalapppaa; ABalppappa; and amphid neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00021558 Y45G5AM.6 Located in striated muscle dense body. WB:WBGene00021559 Y45G5AM.7 Predicted to be located in motile cilium. WB:WBGene00021560 coh-4 Involved in meiotic sister chromatid cohesion. WB:WBGene00021561 Y45G5AM.9 Predicted to enable clathrin binding activity. Predicted to be involved in intracellular transport. Predicted to be located in trans-Golgi network membrane. Predicted to be part of AP-1 adaptor complex. Is an ortholog of human AFTPH (aftiphilin). WB:WBGene00021562 nuo-5 Predicted to enable 4 iron, 4 sulfur cluster binding activity; metal ion binding activity; and oxidoreductase activity, acting on NAD(P)H. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in cellular respiration. Predicted to be part of mitochondrial respiratory chain complex I. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 5. Is an ortholog of human NDUFS1 (NADH:ubiquinone oxidoreductase core subunit S1). WB:WBGene00021563 Y45G12B.2 Predicted to enable metal ion binding activity. Predicted to be located in Golgi apparatus. Is an ortholog of human ZFPL1 (zinc finger protein like 1). WB:WBGene00021564 Y45G12B.3 Predicted to enable 2-hydroxyglutarate dehydrogenase activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in brain disease (multiple) and hereditary spastic paraplegia. Is an ortholog of human L2HGDH (L-2-hydroxyglutarate dehydrogenase). WB:WBGene00021565 Y45G12C.1 Enriched in OLL; PVD; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including levamisole; Zidovudine; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1647) and Protein of unknown function DUF1647. WB:WBGene00021566 Y45G12C.3 Enriched in intestine and pharynx based on microarray studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); hematologic cancer (multiple); and lung disease (multiple). Human GSTP1 enables several functions, including anion binding activity; dinitrosyl-iron complex binding activity; and glutathione peroxidase activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal; Glutathione S-transferase, N-terminal domain; and Thioredoxin-like superfamily. Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). WB:WBGene00021567 Y45G12C.4 Is affected by several genes including bar-1; pry-1; and mir-34 based on tiling array; RNA-seq; and microarray studies. Is affected by aldicarb and fluvastatin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterized oxidoreductase dhs-27; Uncharacterised oxidoreductase Dhs-27; CHK kinase-like; and Protein kinase-like domain superfamily. WB:WBGene00021568 srt-2 Is affected by rsr-2 and pgrn-1 based on tiling array and RNA-seq studies. Is affected by aldicarb based on microarray studies. Is predicted to encode a protein with the following domains: Serpentine type 7TM GPCR chemoreceptor Srt and 7TM GPCR, serpentine receptor class t (Srt). WB:WBGene00021569 Y45G12C.6 Is affected by several genes including clk-1; lin-15B; and cyc-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class r (Str) and Serpentine type 7TM GPCR chemoreceptor Str. WB:WBGene00021570 srd-73 Is affected by several genes including eat-2; pgl-1; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Serpentine type 7TM GPCR chemoreceptor Srd and 7TM GPCR, serpentine receptor class d (Srd). WB:WBGene00021571 srbc-81 Predicted to be located in membrane. WB:WBGene00021572 srd-72 Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Serpentine type 7TM GPCR chemoreceptor Srd and 7TM GPCR, serpentine receptor class d (Srd). WB:WBGene00021573 Y45G12C.10 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00021574 Y45G12C.11 Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. WB:WBGene00021575 Y45G12C.13 No description available WB:WBGene00021576 fbxc-51 Enriched in several structures, including ABalaaaarl; ABalaaaarr; GLR; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00021577 Y46B2A.2 No description available WB:WBGene00021578 Y46B2A.3 Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including allergic rhinitis; carcinoma (multiple); and lung disease (multiple). Is an ortholog of human MUC1 (mucin 1, cell surface associated). WB:WBGene00021579 clec-73 Expressed in intestine. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021580 clec-174 Involved in defense response to Gram-negative bacterium. WB:WBGene00021581 clec-70 Involved in defense response to Gram-positive bacterium. WB:WBGene00021582 clec-71 Involved in defense response to Gram-positive bacterium. WB:WBGene00021583 clec-72 Enriched in DD neuron; PVR; RMED; head mesodermal cell; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on quantitative PCR; microarray; RNA-seq; and proteomic studies. Is affected by twenty-four chemicals including Heme; 1-methylnicotinamide; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021584 Y46C8AL.6 No description available WB:WBGene00021585 clec-74 Enriched in NSM and rectal epithelial cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-one chemicals including tryptophan; 1-methylnicotinamide; and Mercuric Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021586 clec-75 Enriched in head mesodermal cell and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including tryptophan; rotenone; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021587 clec-76 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty chemicals including Heme; tryptophan; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021589 Y46D2A.1 Enriched in muscle cell and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including D-glucose; Zidovudine; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00021590 Y46D2A.2 Enriched in AFD; OLL; PVD; head mesodermal cell; and intestine based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including Heme; rotenone; and D-glucopyranose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00021591 Y46D2A.3 Is affected by several genes including eat-2; tph-1; and cat-2 based on tiling array and RNA-seq studies. Is affected by Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021592 Y46E12A.2 Is affected by several genes including daf-2; clk-1; and dpy-7 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Tunicamycin; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00021593 Y46E12A.3 Predicted to be involved in sensory perception of sound. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 25. Is an ortholog of human GRXCR1 (glutaredoxin and cysteine rich domain containing 1). WB:WBGene00021594 tig-3 Predicted to enable cytokine activity. Predicted to be located in extracellular space. WB:WBGene00021595 Y46E12BL.2 Predicted to be located in membrane. Is an ortholog of human RRP12 (ribosomal RNA processing 12 homolog). WB:WBGene00021596 spsb-2 Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Expressed in hypodermis and intestine. Is an ortholog of human SPSB1 (splA/ryanodine receptor domain and SOCS box containing 1). WB:WBGene00021597 spsb-1 Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of SCF ubiquitin ligase complex. Expressed in arcade cell; excretory system; hypodermis; intestine; and pharyngeal muscle cell. Is an ortholog of human SPSB1 (splA/ryanodine receptor domain and SOCS box containing 1). WB:WBGene00021599 srt-42 Predicted to be located in membrane. WB:WBGene00021600 Y46H3A.4 Enriched in AIZ; rectal epithelial cell; rectum; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and nhr-49 based on RNA-seq and microarray studies. Is affected by twelve chemicals including rotenone; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00021601 Y46H3A.5 Predicted to be involved in lipid metabolic process. WB:WBGene00021602 clec-205 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; metformin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021603 clec-204 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. WB:WBGene00021604 Y46H3C.4 Is affected by several genes including daf-16; nhl-2; and emb-4 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00021605 Y46H3C.5 Enriched in several structures, including ABalppappa; ABarappppa; ABplpaaaaa; germ line; and sensory neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and rotenone based on microarray and RNA-seq studies. WB:WBGene00021606 Y46H3C.6 Enriched in germline precursor cell and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-60 based on microarray and RNA-seq studies. Is affected by four chemicals including rotenone; Alovudine; and allantoin based on RNA-seq studies. WB:WBGene00021607 Y46H3C.7 Enriched in AFD; DB neuron; germ line; neuronal sheath cell; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including D-glucose; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021608 Y46H3D.1 Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00021609 irld-17 Enriched in several structures, including ABaraapapp; ABaraapppp; MSaapaapa; MSaapapa; and pharyngeal cell based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00021610 nhr-237 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in nerve ring; pharynx; tail neurons; and ventral nerve cord. WB:WBGene00021611 nhr-238 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00021612 Y46H3D.8 Is affected by several genes including sir-2.1; mir-34; and rsr-2 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including aldicarb; procyanidin; and cadmium based on microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00021613 ttc-37 Predicted to be involved in nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'. Predicted to be part of Ski complex. Human ortholog(s) of this gene implicated in trichohepatoenteric syndrome 1. Is an ortholog of human SKIC3 (SKI3 subunit of superkiller complex). WB:WBGene00021614 Y47A7.2 Enriched in several structures, including ABarppaapp; ABarpppapp; ABplapaaapa; head mesodermal cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and sek-1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by seven chemicals including stavudine; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00021615 Y47C4A.1 Predicted to enable metalloendopeptidase activity. Predicted to be involved in mitochondrial protein processing. Predicted to be part of m-AAA complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 7. Is an ortholog of human SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin). WB:WBGene00021616 Y47D7A.2 Enriched in DA neuron; VA neuron; body wall muscle cell; hypodermis; and in male based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; csr-1; and nhr-8 based on microarray and RNA-seq studies. Is affected by cadmium and nitroguanidine based on microarray studies. WB:WBGene00021617 Y47D7A.3 Predicted to be located in nucleus. WB:WBGene00021619 Y47D7A.6 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including rotenone; D-glucose; and glycine based on RNA-seq studies. WB:WBGene00021620 Y47D7A.7 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00021621 Y47D7A.9 Enriched in AFD and male-specific anatomical entity based on RNA-seq and microarray studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including methylmercury hydroxide; D-glucose; and Tamoxifen based on RNA-seq and microarray studies. WB:WBGene00021622 hpo-37 Is affected by cyc-1; ubc-9; and ain-1 based on microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00021623 Y47D7A.11 Enriched in body wall muscle cell; male-specific anatomical entity; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; rrf-3; and pmk-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including hydrogen sulfide; multi-walled carbon nanotube; and allantoin based on microarray and RNA-seq studies. WB:WBGene00021624 Y47D7A.12 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by five chemicals including Tunicamycin; Rifampin; and paraquat based on microarray and RNA-seq studies. WB:WBGene00021625 Y47D7A.13 Enriched in DA neuron; VA neuron; intestine; neurons; and seam cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by forty chemicals including hydrogen sulfide; Nitric Oxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00021626 rft-2 Enables riboflavin transmembrane transporter activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A1 (solute carrier family 52 member 1); SLC52A2 (solute carrier family 52 member 2); and SLC52A3 (solute carrier family 52 member 3). WB:WBGene00021627 Y47D7A.15 Enriched in several structures, including ABalapapapa; ABalapppapa; ABplpaaappa; OLQ; and ventral nerve cord based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-seven chemicals including hydrogen sulfide; Ethanol; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00021628 Y47D9A.1 Predicted to enable transferase activity. Predicted to be involved in biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in alacrima, achalasia, and impaired intellectual development syndrome. Is an ortholog of human GMPPA (GDP-mannose pyrophosphorylase A). WB:WBGene00021629 scpl-3 Predicted to enable phosphoprotein phosphatase activity. Is an ortholog of human CTDSPL2 (CTD small phosphatase like 2). WB:WBGene00021630 Y47D9A.3 Enriched in head mesodermal cell; head neurons; hypodermis; and neuronal sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00021631 Y47D9A.4 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00021632 Y47D9A.5 Predicted to be located in membrane. WB:WBGene00021633 Y47G6A.3 Predicted to be located in membrane. WB:WBGene00021634 rde-10 Predicted to be involved in regulation of miRNA-mediated gene silencing; regulation of translation; and regulatory ncRNA-mediated gene silencing. WB:WBGene00021635 Y47G6A.5 Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in cell differentiation; innate immune response; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. WB:WBGene00021636 pcaf-1 Predicted to enable histone H3 acetyltransferase activity. Predicted to be involved in chromatin remodeling and positive regulation of transcription by RNA polymerase II. Predicted to be located in microtubule organizing center and nucleus. Predicted to be part of ATAC complex. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); and rheumatoid arthritis. Is an ortholog of human KAT2A (lysine acetyltransferase 2A). WB:WBGene00021637 Y47G6A.7 Predicted to enable antiporter activity. Predicted to be involved in UDP-glucose transmembrane transport. Predicted to be located in cis-Golgi network and endoplasmic reticulum-Golgi intermediate compartment. Expressed in head. Is an ortholog of human SLC35C2 (solute carrier family 35 member C2). WB:WBGene00021638 Y47G6A.9 Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is an ortholog of human POLR3G (RNA polymerase III subunit G) and POLR3GL (RNA polymerase III subunit GL). WB:WBGene00021639 Y47G6A.13 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00021640 Y47G6A.14 Predicted to enable metal ion binding activity. Is an ortholog of human TRIM55 (tripartite motif containing 55). WB:WBGene00021641 Y47G6A.15 Enriched in several structures, including ASG; enteric muscle; head mesodermal cell; nerve ring neurons; and spermatheca based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; RNA-seq; and microarray studies. Is affected by seventeen chemicals including hydrogen sulfide; Ethanol; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00021643 ccep-290 Involved in non-motile cilium assembly and protein localization to ciliary transition zone. Located in central cylinder. Expressed in amphid neurons and phasmid neurons. WB:WBGene00021644 Y47G6A.18 Predicted to enable phosphatidylinositol-4-phosphate binding activity. Predicted to be involved in Golgi organization and Golgi vesicle transport. Predicted to be located in Golgi cisterna; cytosol; and trans-Golgi network. Is an ortholog of human GOLPH3 (golgi phosphoprotein 3). WB:WBGene00021645 Y47G6A.19 Predicted to enable metallocarboxypeptidase activity and zinc ion binding activity. Predicted to be involved in proteolysis. WB:WBGene00021646 Y47G6A.21 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00021647 Y47G6A.22 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00021648 mis-12 Involved in kinetochore assembly. Located in kinetochore. WB:WBGene00021649 Y47G6A.25 Enriched in germ line; germline precursor cell; head mesodermal cell; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including manganese chloride; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00021650 Y47G6A.26 Enriched in NSM; amphid sheath cell; and in male based on RNA-seq and tiling array studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00021651 miro-3 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by allantoin; Sirolimus; and Doxycycline based on RNA-seq studies. WB:WBGene00021653 Y47G6A.30 Predicted to be located in ribosome. WB:WBGene00021654 Y47G7B.2 Predicted to be located in membrane. WB:WBGene00021655 Y48A5A.1 Predicted to enable unfolded protein binding activity. Predicted to be involved in box H/ACA snoRNP assembly. Predicted to be located in cytoplasm and nucleoplasm. Human ortholog(s) of this gene implicated in dystonia. Is an ortholog of human SHQ1 (SHQ1, H/ACA ribonucleoprotein assembly factor). WB:WBGene00021656 Y48D7A.1 Enriched in GABAergic neurons and muscle cell based on microarray studies. Is affected by several genes including daf-2; eat-2; and rrf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00021657 Y48G1A.1 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00021658 Y48G1A.2 Enriched in AFD; CEP socket cell; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercury hydroxide; and rotenone based on microarray and RNA-seq studies. WB:WBGene00021660 nol-14 Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in nucleolus. Predicted to be part of Noc4p-Nop14p complex and small-subunit processome. Is an ortholog of human NOP14 (NOP14 nucleolar protein). WB:WBGene00021661 mbtr-1 Predicted to enable chromatin binding activity and methylated histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2) and MBTD1 (mbt domain containing 1). WB:WBGene00021662 snpc-3.3 Enriched in AVA; AVE; and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by metformin; Sirolimus; and antimycin based on RNA-seq studies. WB:WBGene00021663 Y48G1BL.4 No description available WB:WBGene00021664 Y48G1BL.5 Enriched in germline precursor cell and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021666 Y48G1BL.7 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00021667 snpc-3.2 Predicted to enable RNA polymerase III type 3 promoter sequence-specific DNA binding activity and bent DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and core promoter sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be located in nucleus. Predicted to be part of snRNA-activating protein complex. Is an ortholog of human SNAPC3 (small nuclear RNA activating complex polypeptide 3). WB:WBGene00021668 Y48G1BM.2 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00021669 Y48G1BM.4 No description available WB:WBGene00021671 Y48G1BM.6 Enriched in neurons and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Alovudine; and metformin based on RNA-seq studies. WB:WBGene00021672 Y48G1BM.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; mex-1; and glh-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00021673 Y48G1BM.8 Enriched in germline precursor cell and head mesodermal cell based on RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and isp-1 based on microarray and RNA-seq studies. Is affected by rotenone; Alovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021675 Y48G1BR.1 Predicted to be located in membrane. WB:WBGene00021676 pid-2 Predicted to be involved in regulatory ncRNA-mediated gene silencing. Predicted to be located in perinuclear region of cytoplasm. WB:WBGene00021677 pgs-1 Predicted to enable CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity. Involved in regulation of cell population proliferation and regulation of mitochondrial membrane potential. Predicted to be located in mitochondrion. Is an ortholog of human PGS1 (phosphatidylglycerophosphate synthase 1). WB:WBGene00021678 Y48G1C.5 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00021679 Y48G1C.6 Enriched in ABplppppaa; ABprppppaa; neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and daf-12 based on microarray and RNA-seq studies. Is affected by four chemicals including rotenone; stavudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: HTH CenpB-type DNA-binding domain; Brinker DNA-binding domain; Homeobox-like domain superfamily; and Tc5 transposase DNA-binding domain. Is an ortholog of human POGK (pogo transposable element derived with KRAB domain). WB:WBGene00021681 Y48G1C.8 Enriched in several structures, including ABplpapapa; NSM; germ line; mechanosensory neurons; and rectal epithelial cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by eight chemicals including rotenone; Zidovudine; and paraquat based on RNA-seq and microarray studies. WB:WBGene00021682 natc-3 Predicted to be involved in mRNA processing. Predicted to be located in cytoplasm. Predicted to be part of spliceosomal complex. Is an ortholog of human NAA38 (N-alpha-acetyltransferase 38, NatC auxiliary subunit). WB:WBGene00021683 mtm-10 Predicted to be located in cytoplasm. Used to study neurodegenerative disease. Is an ortholog of human MTMR10 (myotubularin related protein 10) and MTMR12 (myotubularin related protein 12). WB:WBGene00021685 herc-1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Is an ortholog of human HERC4 (HECT and RLD domain containing E3 ubiquitin protein ligase 4). WB:WBGene00021686 nsun-2 Enables tRNA (cytosine-5-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 5. Is an ortholog of human NSUN2 (NOP2/Sun RNA methyltransferase 2). WB:WBGene00021687 Y48G8AL.7 Enriched in several structures, including ABplpppapa; ABprpppapa; I5 neuron; cholinergic neurons; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; dpy-10; and eat-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; mianserin; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00021689 znf-236 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of several human genes including ZNF208 (zinc finger protein 208); ZNF845 (zinc finger protein 845); and ZNF91 (zinc finger protein 91). WB:WBGene00021690 Y48G8AL.12 Enriched in AFD; ASER; PLM; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by ten chemicals including aldicarb; 1-methylnicotinamide; and nicotinic acid based on microarray and RNA-seq studies. WB:WBGene00021691 Y48G8AL.13 Predicted to be involved in membrane organization and phospholipid homeostasis. Predicted to be located in plasma membrane. Is an ortholog of human TLCD2 (TLC domain containing 2). WB:WBGene00021692 Y48G8AL.15 Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00021693 Y48G8AR.2 Predicted to enable metal ion binding activity. Is an ortholog of human SYTL3 (synaptotagmin like 3). WB:WBGene00021694 Y48G8AR.3 Enriched in neurons and in male based on RNA-seq studies. Is affected by several genes including csr-1; hpl-2; and adr-1 based on tiling array and RNA-seq studies. Is affected by cadmium and Sirolimus based on microarray studies. WB:WBGene00021697 gcn-1 Predicted to enable protein kinase regulator activity. Involved in positive regulation of peptidyl-serine phosphorylation; regulation of apoptotic process; and regulation of translation. Acts upstream of with a positive effect on positive regulation of gene expression. Acts upstream of or within with a negative effect on negative regulation of translation. Predicted to be located in cytosolic ribosome. Expressed in several structures, including body wall musculature; head neurons; hermaphrodite gonad; intestinal cell; and pharyngeal neurons. Is an ortholog of human GCN1 (GCN1 activator of EIF2AK4). WB:WBGene00021698 frl-1 Predicted to enable actin binding activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization and regulation of cell morphogenesis. WB:WBGene00021699 Y48G9A.5 No description available WB:WBGene00021700 Y48G9A.6 Enriched in male based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021701 Y48G9A.7 Enriched in AMshL; AMshR; OLL; and PVD based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and alg-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; rotenone; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00021702 Y48G9A.9 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in motor neuron axon guidance. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Is an ortholog of human PTPN7 (protein tyrosine phosphatase non-receptor type 7); PTPRG (protein tyrosine phosphatase receptor type G); and PTPRZ1 (protein tyrosine phosphatase receptor type Z1). WB:WBGene00021703 cpt-3 Predicted to enable carnitine O-palmitoyltransferase activity. Predicted to be involved in carnitine metabolic process and fatty acid metabolic process. Predicted to be located in mitochondrion. WB:WBGene00021704 Y48G9A.11 Enriched in g1AL; g1AR; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; elt-2; and sir-2.1 based on microarray; RNA-seq; and tiling array studies. Is affected by seven chemicals including manganese chloride; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00021706 srbc-39 Predicted to be located in membrane. WB:WBGene00021707 srbc-38 Predicted to be located in membrane. WB:WBGene00021708 srbc-37 Predicted to be located in membrane. WB:WBGene00021709 ugt-29 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Expressed in pharynx; tail; and vulval muscle. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). WB:WBGene00021710 cyp-33C11 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). WB:WBGene00021711 wago-11 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and alg-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021712 Y49F6A.4 No description available WB:WBGene00021713 Y49F6A.5 Enriched in germline precursor cell and muscle cell based on RNA-seq and microarray studies. Is affected by several genes including daf-2; npr-1; and tph-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; tert-Butylhydroperoxide; and allantoin based on microarray and RNA-seq studies. WB:WBGene00021714 cyh-1 Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. WB:WBGene00021715 Y49F6B.2 Predicted to be involved in RNA processing. Predicted to be located in nucleolus. Is an ortholog of human DNTTIP2 (deoxynucleotidyltransferase terminal interacting protein 2). WB:WBGene00021716 fbxb-112 Enriched in ABplaapaap and ABpraapaap based on single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by ten chemicals including Tunicamycin; stavudine; and Rifampin based on microarray; RNA-seq; and proteomic studies. WB:WBGene00021717 sdz-32 Enriched in AVJ; body wall muscle cell; cholinergic neurons; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and daf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00021718 Y49F6B.6 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00021719 fbxb-104 Enriched in amphid neurons; hypodermis; intestine; and muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021720 Y49F6B.8 Enriched in several structures, including ABplaapappp; AVG; RIM; amphid sheath cell; and command interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including Ethanol; methylmercuric chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1265 and Protein of unknown function (DUF1265). WB:WBGene00021721 Y49F6B.9 Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase). WB:WBGene00021722 srz-5 Predicted to be located in membrane. WB:WBGene00021723 bath-8 Is affected by several genes including daf-2; sir-2.1; and hpl-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including multi-walled carbon nanotube; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00021724 Y49F6C.2 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalpapaap; ABaraappaa; and ABarappaap based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00021725 bath-9 Enriched in several structures, including cholinergic neurons; excretory cell; head mesodermal cell; interfacial epithelial cell; and ventral nerve cord based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00021726 bath-10 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalpapaap; neurons; and pharyngeal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and mianserin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and TRAF-like. WB:WBGene00021727 bath-23 Enriched in MSaapapa; MSpapapa; NSM; germ line; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including clk-1; unc-30; and hpl-2 based on microarray and RNA-seq studies. Is affected by aldicarb and Atrazine based on microarray studies. WB:WBGene00021728 Y49F6C.6 Enriched in MSpaaapa and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including clk-1; fog-2; and hda-1 based on microarray and RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00021729 Y49F6C.7 Enriched in muscle cell based on microarray studies. Is affected by several genes including hpl-2; drh-3; and spn-4 based on tiling array; RNA-seq; and proteomic studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021730 Y49F6C.8 Enriched in MSaaaaapa; germ line; pharyngeal muscle cell; and pharyngeal-intestinal valve based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eighteen chemicals including aldicarb; rotenone; and Tunicamycin based on microarray; RNA-seq; and proteomic studies. WB:WBGene00021731 Y49G5A.1 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00021732 Y49G5B.1 Expressed in gonad. WB:WBGene00021733 otub-2 Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and cysteine-type deubiquitinase activity. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human OTUD7A (OTU deubiquitinase 7A) and OTUD7B (OTU deubiquitinase 7B). WB:WBGene00021734 Y50C1A.2 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; ABalappppaa; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; sir-2.1; and sek-1 based on microarray and RNA-seq studies. Is affected by Sodium Chloride and dibromoacetic acid based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: WD40/YVTN repeat-like-containing domain superfamily and WD40-repeat-containing domain superfamily. WB:WBGene00021735 Y50D4A.1 Enriched in several structures, including ABplaapapa; ABplpapapa; ABpraapapa; germ line; and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including mianserin; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00021736 wrb-1 Predicted to enable protein-membrane adaptor activity. Predicted to be involved in tail-anchored membrane protein insertion into ER membrane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of GET complex. WB:WBGene00021737 Y50D4A.3 Is affected by several genes including fbf-1; spn-4; and mir-34 based on microarray and RNA-seq studies. Is affected by adsorbable organic bromine compound; Sirolimus; and allantoin based on microarray studies. WB:WBGene00021738 Y50D4A.4 Predicted to be involved in regulation of autophagy. Predicted to be located in late endosome membrane. Predicted to be part of Mon1-Ccz1 complex. Is an ortholog of human RMC1 (regulator of MON1-CCZ1). WB:WBGene00021739 Y50D4A.5 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00021740 Y50D4B.1 Enriched in neurons and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and let-7 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eleven chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00021741 Y50D4B.2 Predicted to be involved in glycolipid biosynthetic process. Predicted to be located in lipid droplet. Is an ortholog of human SCCPDH (saccharopine dehydrogenase (putative)). WB:WBGene00021743 Y50D4B.4 Predicted to enable peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity. Predicted to be involved in glycoprotein catabolic process and protein quality control for misfolded or incompletely synthesized proteins. Predicted to be located in cytosol and nucleus. WB:WBGene00021744 clec-203 Predicted to be located in membrane. WB:WBGene00021745 Y50D4B.6 Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); and prostate cancer. Is an ortholog of human FLT3 (fms related receptor tyrosine kinase 3). WB:WBGene00021746 Y50D4B.7 Is affected by several genes including elt-2; clk-1; and tph-1 based on microarray and RNA-seq studies. Is affected by bortezomib; Doxycycline; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00021747 Y50D4C.2 Enriched in germ line and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including bisphenol S; nicotine; and Alovudine based on RNA-seq; proteomic; and microarray studies. WB:WBGene00021748 Y50D4C.3 Predicted to enable RNA binding activity. Predicted to be involved in mRNA processing. Predicted to be located in nucleus. Is an ortholog of human TDRD3 (tudor domain containing 3). WB:WBGene00021749 Y50D4C.5 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; XXX cell; germ line; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by six chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq studies. WB:WBGene00021750 Y50D4C.6 Predicted to enable metal ion binding activity and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. Is an ortholog of human ADO (2-aminoethanethiol dioxygenase). WB:WBGene00021751 Y50D7A.1 Enriched in ABalaaaala; ABalaapaaa; ABalpapaap; ABarappaap; and mechanosensory neurons based on microarray and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; aak-2; and lin-28 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021752 xpd-1 Predicted to enable DNA helicase activity and damaged DNA binding activity. Predicted to be involved in positive regulation of mitotic recombination and transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; gastrointestinal system cancer (multiple); hematologic cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of human ERCC2 (ERCC excision repair 2, TFIIH core complex helicase subunit). WB:WBGene00021753 Y50D7A.3 Predicted to enable ATP binding activity; calmodulin binding activity; and phosphorylase kinase activity. Predicted to be involved in glycogen biosynthetic process and phosphorylation. Predicted to be part of phosphorylase kinase complex. Human ortholog(s) of this gene implicated in glycogen storage disease IXc and liver cirrhosis. Is an ortholog of human PHKG2 (phosphorylase kinase catalytic subunit gamma 2). WB:WBGene00021754 hpo-29 Predicted to be located in cytoplasm. Predicted to be part of NatA complex. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 50. Is an ortholog of human NAA15 (N-alpha-acetyltransferase 15, NatA auxiliary subunit) and NAA16 (N-alpha-acetyltransferase 16, NatA auxiliary subunit). WB:WBGene00021755 hpo-38 Enriched in AWA; arcade cell; germ line; neurons; and pharyngeal-intestinal valve cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including mianserin; multi-walled carbon nanotube; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00021756 Y50D7A.8 Expressed in head. WB:WBGene00021757 taco-1 Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human TACO1 (translational activator of cytochrome c oxidase I). WB:WBGene00021758 Y50D7A.10 Predicted to enable Arp2/3 complex binding activity. Predicted to be involved in actin filament debranching and negative regulation of Arp2/3 complex-mediated actin nucleation. Is an ortholog of human GMFB (glia maturation factor beta) and GMFG (glia maturation factor gamma). WB:WBGene00021761 Y51B11A.1 No description available WB:WBGene00021762 Y51F10.1 No description available WB:WBGene00021763 grif-1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Is an ortholog of human RNF227 (ring finger protein 227). WB:WBGene00021764 Y51F10.3 Predicted to be located in membrane. WB:WBGene00021765 Y51F10.4 Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC38A10 (solute carrier family 38 member 10). WB:WBGene00021766 hex-4 Enables beta-N-acetylgalactosaminidase activity. Involved in polysaccharide metabolic process. Expressed in seam cell. Is an ortholog of human HEXD (hexosaminidase D). WB:WBGene00021768 Y51F10.7 Enriched in OLL; PVD; head mesodermal cell; intestine; and pharyngeal muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including cholesterol; lathosterol; and diallyl trisulfide based on microarray and RNA-seq studies. WB:WBGene00021769 Y51F10.8 No description available WB:WBGene00021771 spe-48 Predicted to enable ubiquitin binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be part of ESCRT I complex. WB:WBGene00021772 math-45 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including rotenone; mianserin; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00021773 fbxb-42 Enriched in several structures, including ABalaaaala; ABalaapaaa; MSpppaaa; head mesodermal cell; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-7; and gld-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; methylmercuric chloride; and bisphenol A based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021774 fbxb-43 Enriched in several structures, including ABalaaaala; ABalaapaaa; MSpppaaa; head mesodermal cell; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including hydrogen sulfide; methylmercuric chloride; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00021776 Y51H7BR.4 Predicted to be located in membrane. WB:WBGene00021778 Y51H7BR.7 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; aak-2; and lin-29 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including aldicarb; Rifampin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SPEC3/Stum and Ectodermal ciliogenesis protein. WB:WBGene00021779 Y51H7C.1 Predicted to enable peptidase activity. Predicted to be involved in proteolysis. WB:WBGene00021780 scl-17 Predicted to be located in extracellular space. Is an ortholog of several human genes including CRISPLD1 (cysteine rich secretory protein LCCL domain containing 1); GLIPR1 (GLI pathogenesis related 1); and PI15 (peptidase inhibitor 15). WB:WBGene00021781 Y51H7C.3 Enriched in several structures, including ABarppaapp; ABarpppapp; germ line; neurons; and ventral nerve cord based on tiling array; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021783 alkb-1 Predicted to enable ferrous iron binding activity; oxidative DNA demethylase activity; and oxidative RNA demethylase activity. Predicted to be involved in oxidative RNA demethylation and oxidative single-stranded DNA demethylation. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human ALKBH1 (alkB homolog 1, histone H2A dioxygenase). WB:WBGene00021784 cogc-4 Involved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in Saul-Wilson syndrome and congenital disorder of glycosylation type IIj. Is an ortholog of human COG4 (component of oligomeric golgi complex 4). WB:WBGene00021785 Y51H7C.7 Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA and regulation of gene expression. Predicted to be located in nucleolus. Predicted to be part of exosome (RNase complex). Is an ortholog of human C1D (C1D nuclear receptor corepressor). WB:WBGene00021786 Y51H7C.8 Enriched in CEP socket cell; pharyngeal muscle cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including hydrogen sulfide; antimycin; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00021787 Y51H7C.9 Predicted to enable L-serine ammonia-lyase activity and L-threonine ammonia-lyase activity. Predicted to be involved in L-serine catabolic process; isoleucine biosynthetic process; and threonine catabolic process. WB:WBGene00021788 Y51H7C.10 Predicted to be located in membrane. WB:WBGene00021789 nol-6 Predicted to enable RNA binding activity. Involved in negative regulation of innate immune response. Predicted to be located in condensed nuclear chromosome and nucleolus. Predicted to be part of CURI complex; UTP-C complex; and small-subunit processome. Is an ortholog of human NOL6 (nucleolar protein 6). WB:WBGene00021790 Y51H7C.12 Predicted to enable transferase activity. Predicted to be located in membrane. WB:WBGene00021791 Y51H7C.13 Enriched in ABplpaaaap; ABprpaaaap; amphid sheath cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-nine chemicals including Ethanol; 1-methylnicotinamide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00021792 Y52D5A.1 Enriched in body wall muscle cell and hypodermis based on tiling array studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including methylmercuric chloride; Tunicamycin; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00021793 Y52D5A.2 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00021794 Y52E8A.1 Predicted to enable ATP binding activity; helicase activity; and hydrolase activity. WB:WBGene00021795 Y52E8A.2 Predicted to enable metal ion binding activity. WB:WBGene00021796 Y52E8A.3 Enriched in ABarpaaa; amphid socket cell; intestine; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and age-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including 1-methylnicotinamide; Mercuric Chloride; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Thioredoxin-like superfamily; and Thioredoxin-like. Is an ortholog of human NXNL2 (nucleoredoxin like 2). WB:WBGene00021797 plep-1 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00021798 Y52E8A.6 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00021799 Y53G8AL.1 Enriched in neurons and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; metformin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Forkhead-associated (FHA) domain; SMAD/FHA domain superfamily; and FHA domain. WB:WBGene00021800 nduf-9 Predicted to be involved in mitochondrial respiratory chain complex I assembly and ubiquinone-6 biosynthetic process. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Expressed in head and tail. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 26. Is an ortholog of human NDUFA9 (NADH:ubiquinone oxidoreductase subunit A9). WB:WBGene00021801 Y53G8AL.3 Enriched in neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Atrazine and Sirolimus based on microarray studies. WB:WBGene00021802 Y53G8AM.1 No description available WB:WBGene00021804 Y53G8AM.4 Predicted to enable metal ion binding activity. Predicted to be located in membrane. Expressed in amphid neurons and phasmid neurons. WB:WBGene00021805 nspg-7.2 Enriched in DD neuron; intestine; muscle cell; and neurons based on RNA-seq and microarray studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including tryptophan; Tunicamycin; and TPEN based on microarray and RNA-seq studies. WB:WBGene00021806 Y53G8AM.6 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; aak-2; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including antimycin; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00021807 Y53G8AM.7 Enriched in several structures, including ABalappaap; ABarppaapp; ABarpppapp; ABplaapappp; and ABplapaaaap based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and alg-1 based on microarray and RNA-seq studies. Is affected by Rifampin; allantoin; and resveratrol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Zinc finger, RING/FYVE/PHD-type; zinc-RING finger domain; and Zinc finger, RING-type. WB:WBGene00021808 Y53G8AM.8 Enriched in XXXL; XXXR; neurons; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; hsf-1; and eat-2 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: HTH CenpB-type DNA-binding domain; Homeobox-like domain superfamily; and Tc5 transposase DNA-binding domain. WB:WBGene00021809 Y53G8AR.1 Is affected by several genes including daf-2; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00021810 phf-15 Predicted to enable histone binding activity and nucleosome binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human JADE3 (jade family PHD finger 3). WB:WBGene00021811 ral-1 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including determination of adult lifespan; multivesicular body assembly; and positive regulation of vulval development. Predicted to be located in plasma membrane. Expressed in several structures, including excretory canal; germ line; tail; vulva; and vulval precursor cell. Human ortholog(s) of this gene implicated in pancreatic ductal adenocarcinoma. Is an ortholog of human RALA (RAS like proto-oncogene A). WB:WBGene00021812 Y53G8AR.5 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in nucleus. Is an ortholog of human RNF25 (ring finger protein 25). WB:WBGene00021813 Y53G8AR.6 Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to be located in nucleus. Is an ortholog of human SARNP (SAP domain containing ribonucleoprotein). WB:WBGene00021814 mfsd-8 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Is an ortholog of human MFSD8 (major facilitator superfamily domain containing 8). WB:WBGene00021815 Y53G8AR.8 Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Located in mitochondrion. Is an ortholog of human DMAC2 (distal membrane arm assembly component 2). WB:WBGene00021816 Y53G8AR.9 Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Is an ortholog of human ZC3H10 (zinc finger CCCH-type containing 10). WB:WBGene00021817 Y53G8B.1 Predicted to enable glutathione transferase activity and maleylacetoacetate isomerase activity. Predicted to be involved in L-phenylalanine catabolic process and glutathione metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human GSTZ1 (glutathione S-transferase zeta 1). WB:WBGene00021818 Y53G8B.2 Predicted to enable diacylglycerol O-acyltransferase activity. Predicted to be involved in triglyceride biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human MOGAT1 (monoacylglycerol O-acyltransferase 1) and MOGAT2 (monoacylglycerol O-acyltransferase 2). WB:WBGene00021819 Y53G8B.3 Is affected by several genes including daf-2; glp-1; and npr-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00021820 nipa-1 Predicted to enable magnesium ion transmembrane transporter activity. Involved in adult locomotory behavior. Located in neuronal cell body. Used to study hereditary spastic paraplegia. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 6 and hereditary spastic paraplegia 6. Is an ortholog of human NIPAL1 (NIPA like domain containing 1). WB:WBGene00021821 Y54B9A.1 Enriched in OLL; PVD; and neurons based on microarray and RNA-seq studies. Is affected by several genes including hda-1; mir-34; and ints-6 based on microarray and RNA-seq studies. Is affected by six chemicals including sesamin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: GETHR pentapeptide repeat and GETHR pentapeptide repeat (5 copies). WB:WBGene00021823 Y54C5B.1 No description available WB:WBGene00021826 txl-1 Predicted to enable protein-disulfide reductase activity. Predicted to be located in cytosol. Is an ortholog of human TXNL1 (thioredoxin like 1). WB:WBGene00021827 dnc-6 Predicted to enable dynein complex binding activity. Predicted to be involved in mitotic spindle organization. Part of dynactin complex. Is an ortholog of human DCTN6 (dynactin subunit 6). WB:WBGene00021828 Y54E10A.6 Predicted to enable RNA binding activity. Predicted to contribute to phenylalanine-tRNA ligase activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation. Is an ortholog of human LRRC47 (leucine rich repeat containing 47). WB:WBGene00021829 mrpl-17 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL17 (mitochondrial ribosomal protein L17). WB:WBGene00021830 Y54E10A.10 Predicted to enable rRNA binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and ribosomal large subunit assembly. Predicted to be located in nucleolus. Is an ortholog of human RPF2 (ribosome production factor 2 homolog). WB:WBGene00021831 Y54E10A.11 Predicted to enable ribosomal large subunit binding activity and ubiquitin protein ligase activity. Predicted to be involved in rescue of stalled ribosome and ribosome-associated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. Predicted to be part of RQC complex. Is an ortholog of human LTN1 (listerin E3 ubiquitin protein ligase 1). WB:WBGene00021832 syp-5 Enriched in germ line; germline precursor cell; head mesodermal cell; neurons; and retrovesicular ganglion based on proteomic; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; hsf-1; and let-7 based on microarray; proteomic; and RNA-seq studies. Is affected by twelve chemicals including manganese chloride; D-glucose; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00021833 Y54E10A.13 Enriched in NSM; body wall muscle cell; germline precursor cell; and hypodermis based on tiling array studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on microarray and RNA-seq studies. Is affected by Psoralens and allantoin based on RNA-seq studies. WB:WBGene00021834 mab-31 Involved in nematode male tail tip morphogenesis and transforming growth factor beta receptor signaling pathway. Located in nucleus. Expressed in hyp7 syncytium; intestine; pharynx; ray; and socket cell. WB:WBGene00021835 Y54E10A.17 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; anterior hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: DOMON domain. WB:WBGene00021838 Y54E10BL.3 Predicted to be located in membrane. WB:WBGene00021839 nduf-5 Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Is an ortholog of human NDUFS5 (NADH:ubiquinone oxidoreductase subunit S5). WB:WBGene00021840 pign-1 Predicted to enable mannose-ethanolamine phosphotransferase activity. Located in endoplasmic reticulum membrane. Expressed in body wall musculature; hypodermis; intestine; and pharynx. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 1. Is an ortholog of human PIGN (phosphatidylinositol glycan anchor biosynthesis class N). WB:WBGene00021841 Y54E10BR.2 Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in Golgi to plasma membrane protein transport; intracellular protein transport; and protein localization to Golgi apparatus. Predicted to be located in Golgi apparatus. Is an ortholog of human ARFRP1 (ADP ribosylation factor related protein 1). WB:WBGene00021842 rnf-126 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm. Is an ortholog of human RNF115 (ring finger protein 115) and RNF126 (ring finger protein 126). WB:WBGene00021843 Y54E10BR.4 Predicted to enable RNA endonuclease activity. Predicted to be involved in maturation of SSU-rRNA. Located in cytoplasm. Expressed in neurons. Is an ortholog of human NOB1 (NIN1 (RPN12) binding protein 1 homolog). WB:WBGene00021844 sec-11 Predicted to enable peptidase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of signal peptidase complex. Is an ortholog of human SEC11C (SEC11 homolog C, signal peptidase complex subunit). WB:WBGene00021845 rpb-7 Predicted to enable single-stranded DNA binding activity; single-stranded RNA binding activity; and translation initiation factor binding activity. Predicted to be involved in regulation of gene expression and transcription initiation at RNA polymerase II promoter. Predicted to be located in P-body. Predicted to be part of RNA polymerase II, core complex. Is an ortholog of human POLR2G (RNA polymerase II subunit G). WB:WBGene00021846 ztf-23 Enriched in MSpaaapa; PLM; germ line; hypodermis; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and gld-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type; Zinc finger, C2H2 type; and Zinc finger C2H2 superfamily. WB:WBGene00021847 Y54F10AL.1 Predicted to enable calcium ion transmembrane transporter activity and manganese ion transmembrane transporter activity. Predicted to be involved in Golgi calcium ion homeostasis and metal ion transport. Predicted to be located in Golgi apparatus. Expressed in head. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIk. Is an ortholog of human TMEM165 (transmembrane protein 165). WB:WBGene00021848 nhr-239 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in head neurons and pharyngeal neurons. WB:WBGene00021849 ndua-8 Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane; mitochondrial intermembrane space; and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Is an ortholog of human NDUFA8 (NADH:ubiquinone oxidoreductase subunit A8). WB:WBGene00021850 Y54F10AM.6 Enriched in several structures, including ABalpppapa; ABplpapapa; excretory cell; interfacial epithelial cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including Heme; methylmercury hydroxide; and rotenone based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Uncharacterized protein T19C3.2-like. WB:WBGene00021852 Y54F10AM.8 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid catabolic process. Predicted to be located in extracellular region. Is an ortholog of human PLBD2 (phospholipase B domain containing 2). WB:WBGene00021853 Y54F10AM.11 Enriched in several structures, including ABaraapapp; AVG; RIM; command interneuron; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; rotenone; and iron oxide nanoparticle based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00021854 Y54F10AR.1 Predicted to enable phospholipid binding activity and phospholipid transporter activity. Predicted to be involved in intermembrane lipid transfer and phospholipid transport. Predicted to be located in cytoplasm. Is an ortholog of human PITPNA (phosphatidylinositol transfer protein alpha). WB:WBGene00021855 Y54F10AR.2 Predicted to enable exonuclease activity. WB:WBGene00021856 ppm-1.D Predicted to enable mitogen-activated protein kinase binding activity and protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of gene expression, epigenetic. Predicted to be located in cytosol and nucleus. Expressed in distal tip cell and germline blastomere. Human ortholog(s) of this gene implicated in breast cancer and pre-malignant neoplasm. Is an ortholog of human PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D). WB:WBGene00021857 iffb-1 Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Is an ortholog of human EIF5B (eukaryotic translation initiation factor 5B). WB:WBGene00021858 Y54F10BM.3 Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in synaptic membrane adhesion. Expressed in anterior gonad arm. WB:WBGene00021859 fbxa-39 Is affected by several genes including skn-1; eat-2; and lin-35 based on microarray; RNA-seq; and tiling array studies. Is affected by six chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00021860 fbxa-9 Is affected by several genes including elt-2; lin-29; and csr-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by Tunicamycin; paraquat; and Atrazine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00021861 Y54F10BM.6 Predicted to enable metal ion binding activity. Predicted to be located in membrane. WB:WBGene00021862 fbxa-48 Is affected by several genes including daf-2; hsf-1; and elt-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including methylmercuric chloride; Tunicamycin; and D-glucopyranose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00021863 Y54F10BM.9 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalaappppa; germ line; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including D-glucose; Cry5B; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021864 fbxa-1 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including age-1; eat-2; and smg-1 based on microarray and RNA-seq studies. Is affected by antimycin based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00021865 fbxa-66 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nineteen chemicals including methylmercury hydroxide; bisphenol A; and Cadmium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00021866 Y54F10BM.12 Enriched in GLR; body wall muscle cell; coelomocyte; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including pgl-1; fog-2; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including mianserin; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021867 Y54F10BM.13 Predicted to enable JUN kinase phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in cytoplasm. Is an ortholog of human DUSP19 (dual specificity phosphatase 19). WB:WBGene00021868 atln-1 Predicted to enable GTP binding activity and GTPase activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hereditary sensory neuropathy type 1D; hereditary sensory neuropathy type 1F; and hereditary spastic paraplegia 3A. Is an ortholog of human ATL3 (atlastin GTPase 3). WB:WBGene00021869 vrp-1 Expressed in intestinal cell. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021870 samt-1 Predicted to enable molybdate ion transmembrane transporter activity. Predicted to be involved in molybdate ion transport. Predicted to be located in plasma membrane. Is an ortholog of human MFSD5 (major facilitator superfamily domain containing 5). WB:WBGene00021871 dml-1 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021872 clec-85 Expressed in intestine. WB:WBGene00021873 clec-82 Involved in defense response to Gram-positive bacterium. WB:WBGene00021875 Y54G2A.10 Enriched in amphid sheath cell; head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Ethanol; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021876 Y54G2A.11 Predicted to be located in membrane. WB:WBGene00021877 Y54G2A.12 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 15. Is an ortholog of human CDC40 (cell division cycle 40). WB:WBGene00021878 Y54G2A.13 Predicted to be located in membrane. WB:WBGene00021879 clec-83 Enriched in head mesodermal cell and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq; proteomic; and microarray studies. Is affected by fifteen chemicals including methylmercuric chloride; D-glucose; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021880 Y54G2A.15 Enriched in amphid sheath cell; seam cell; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00021881 Y54G2A.16 Predicted to be located in membrane. WB:WBGene00021882 nprt-1 Predicted to enable nicotinate phosphoribosyltransferase activity. Predicted to be involved in NAD salvage and response to oxidative stress. Predicted to be located in cytosol. Is an ortholog of human NAPRT (nicotinate phosphoribosyltransferase). WB:WBGene00021883 Y54G2A.18 Acts upstream of or within IRE1-mediated unfolded protein response. Located in membrane raft. Human ortholog(s) of this gene implicated in deafness, dystonia, and cerebral hypomyelination and sensorineural hearing loss. Is an ortholog of human BCAP29 (B cell receptor associated protein 29). WB:WBGene00021884 Y54G2A.19 Enriched in germ line; intestine; neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and gld-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including rotenone; Zidovudine; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00021885 Y54G2A.20 Enriched in NSM based on tiling array studies. Is affected by several genes including skn-1; pgl-1; and sod-2 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and bortezomib based on RNA-seq studies. WB:WBGene00021886 Y54G2A.21 Enriched in AVK; germ line; sensory neurons; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Alovudine; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00021887 fbxc-45 Enriched in germ line; germline precursor cell; and head mesodermal cell based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including manganese chloride; Alovudine; and stavudine based on RNA-seq studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF3557. WB:WBGene00021888 manf-1 Enables sulfatide binding activity. Involved in developmental growth and regulation of response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum and extracellular space. Expressed in several structures, including anus; excretory gland cell; pharynx; rectal valve cell; and somatic cell. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; carcinoma (multiple); and pancreatic cancer. Is an ortholog of human CDNF (cerebral dopamine neurotrophic factor). WB:WBGene00021889 Y54G2A.24 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including hydrogen sulfide; methylmercury hydroxide; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00021890 Y54G2A.26 Enriched in excretory gland cell; germ line; head mesodermal cell; neuronal sheath cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and eat-2 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by eight chemicals including hydrogen sulfide; Cry5B; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021892 Y54G2A.28 Enriched in OLL; PVD; germline precursor cell; intestine; and tail hypodermis based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00021893 ndnf-1 Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism. Is an ortholog of human NDNF (neuron derived neurotrophic factor). WB:WBGene00021894 Y54G2A.32 Enriched in AIN; PLM; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00021895 clec-84 Enriched in AIA; MC neuron; head mesodermal cell; intestine; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021897 ser-6 Enables octopamine receptor activity. Involved in positive regulation of fatty acid beta-oxidation by octopamine signaling pathway. Predicted to be located in dendrite. Expressed in intestine; neurons; and in male. WB:WBGene00021898 Y54G2A.36 Predicted to be located in membrane. WB:WBGene00021899 Y54H5A.1 Predicted to be involved in ribosome biogenesis. Predicted to be located in nucleolus. Is an ortholog of human GRWD1 (glutamate rich WD repeat containing 1). WB:WBGene00021900 Y54H5A.2 Enriched in several structures, including ABarppaapp; GLR; germ line; lateral ganglion; and pharyngeal cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; gld-1; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including bisphenol S; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein Hgh1; Protein HGH1 N-terminal; Domain of unknown function (DUF383); Domain of unknown function (DUF384); Protein HGH1 C-terminal; Armadillo-like helical; Armadillo-type fold; and Phosphorylation site. Is an ortholog of human HGH1 (HGH1 homolog). WB:WBGene00021901 rbm-42 Predicted to enable mRNA binding activity and snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U12-type spliceosomal complex. Is an ortholog of human RBM42 (RNA binding motif protein 42). WB:WBGene00021902 oxy-4 Predicted to enable 4 iron, 4 sulfur cluster binding activity and metal ion binding activity. Predicted to be involved in iron-sulfur cluster assembly. Predicted to be part of CIA complex. Is an ortholog of human CIAO3 (cytosolic iron-sulfur assembly component 3). WB:WBGene00021904 gtf-2H5 Contributes to damaged DNA binding activity. Involved in nucleotide-excision repair and transcription by RNA polymerase II. Predicted to be located in chromosome and nucleus. Predicted to be part of transcription factor TFIIH core complex and transcription factor TFIIH holo complex. Expressed widely. Used to study trichothiodystrophy. Human ortholog(s) of this gene implicated in photosensitive trichothiodystrophy 3. Is an ortholog of human GTF2H5 (general transcription factor IIH subunit 5). WB:WBGene00021905 helq-1 Enables ATPase binding activity and single-stranded DNA helicase activity. Involved in DNA metabolic process. Predicted to be located in chromosome and nucleus. Is an ortholog of human HELQ (helicase, POLQ like). WB:WBGene00021906 Y55B1AR.2 Enriched in several structures, including ABplpppaapa; ABprpppaapa; germ line; head mesodermal cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and let-7 based on tiling array; proteomic; RNA-seq; and microarray studies. Is affected by nine chemicals including bisphenol S; Zidovudine; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021907 Y55B1AR.3 Enriched in NSM and seam cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Sodium Chloride; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00021908 Y55B1AR.4 Enriched in sensory neurons and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00021909 Y55B1BL.1 Enriched in several structures, including ABarpaapap; ABarpaappa; excretory system; hypodermis; and neurons based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Rifampin; D-glucose; and stavudine based on microarray and RNA-seq studies. WB:WBGene00021910 stim-1 Enables calcium channel regulator activity and identical protein binding activity. Involved in several processes, including ovulation; positive regulation of engulfment of apoptotic cell; and store-operated calcium entry. Located in cytoplasm; plasma membrane; and somatodendritic compartment. Expressed in gonadal sheath cell; intestine; spermatheca; and uterine toroidal epithelial cell. Human ortholog(s) of this gene implicated in several diseases, including Stormorken syndrome; gastrointestinal system cancer (multiple); and immunodeficiency 10. Is an ortholog of human STIM1 (stromal interaction molecule 1). WB:WBGene00021911 affl-1 Enriched in excretory gland cell and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and met-2 based on microarray and RNA-seq studies. Is affected by Tunicamycin; Sirolimus; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00021912 affl-2 Predicted to be located in cytoplasm and nucleus. Expressed widely. WB:WBGene00021913 cec-8 Predicted to enable methylated histone binding activity. Predicted to be involved in chromosome attachment to the nuclear envelope and regulation of gene expression. Predicted to be located in nuclear inner membrane. WB:WBGene00021914 magu-1 Predicted to be located in cell-cell junction and plasma membrane. Expressed in arcade cell; intestine; and marginal cell. Is an ortholog of human MPP7 (MAGUK p55 scaffold protein 7). WB:WBGene00021915 Y55D5A.1 Expressed in ciliated neurons and intestine. WB:WBGene00021917 Y55D5A.3 Predicted to enable fatty acid amide hydrolase activity. Predicted to be involved in N-acylethanolamine metabolic process and fatty acid metabolic process. Predicted to be located in lysosome and membrane. Is an ortholog of human NAAA (N-acylethanolamine acid amidase). WB:WBGene00021918 Y55D5A.4 Enriched in DVC; head mesodermal cell; and muscle cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00021919 cutl-25 Predicted to be located in membrane. WB:WBGene00021920 mrps-25 Predicted to be a structural constituent of ribosome. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 50. Is an ortholog of human MRPS25 (mitochondrial ribosomal protein S25). WB:WBGene00021921 rbm-39 Predicted to enable chromatin DNA binding activity. Predicted to be involved in nuclear envelope organization. Predicted to be located in nucleus. Expressed in PVDL; PVDR; neurons; and tail. Is an ortholog of human RBM39 (RNA binding motif protein 39). WB:WBGene00021922 atg-3 Predicted to enable Atg8-family ligase activity. Involved in macroautophagy. Predicted to be located in cytosol and phagophore assembly site. Is an ortholog of human ATG3 (autophagy related 3). WB:WBGene00021923 Y55F3AM.5 Predicted to enable Arp2/3 complex binding activity. Predicted to be involved in endocytosis. Is an ortholog of human NCKIPSD (NCK interacting protein with SH3 domain). WB:WBGene00021925 immp-2 Predicted to enable endopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial inner membrane peptidase complex. Is an ortholog of human IMMP2L (inner mitochondrial membrane peptidase subunit 2). WB:WBGene00021926 Y55F3AM.9 Predicted to enable K48-linked deubiquitinase activity and cysteine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human MINDY1 (MINDY lysine 48 deubiquitinase 1) and MINDY2 (MINDY lysine 48 deubiquitinase 2). WB:WBGene00021927 abhd-14 Predicted to enable hydrolase activity. Predicted to be located in cytoplasm. Is an ortholog of human ABHD14B (abhydrolase domain containing 14B). WB:WBGene00021928 Y55F3AM.11 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00021929 dcap-1 Predicted to enable mRNA binding activity. Involved in several processes, including determination of adult lifespan; nematode larval development; and response to heat. Located in P granule and P-body. Expressed in head; motor neurons; neurons; tail; and touch receptor neurons. Is an ortholog of human DCP1A (decapping mRNA 1A) and DCP1B (decapping mRNA 1B). WB:WBGene00021930 Y55F3AM.13 Enriched in germ line; rectal epithelial cell; rectum; and somatic gonad precursor based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by six chemicals including Rifampin; allantoin; and Capsaicin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00021931 znf-782 Expressed in dorsal nerve cord; head muscle; intestine; and ventral nerve cord. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type; Zinc finger, C2H2 type; Zinc finger C2H2 superfamily; and C2H2-type zinc finger. Is an ortholog of several human genes including ZNF155 (zinc finger protein 155); ZNF235 (zinc finger protein 235); and ZNF569 (zinc finger protein 569). WB:WBGene00021932 cox-18 Predicted to enable membrane insertase activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly and protein insertion into mitochondrial inner membrane from matrix. Predicted to be located in membrane and mitochondrion. Is an ortholog of human COX18 (cytochrome c oxidase assembly factor COX18). WB:WBGene00021933 Y55F3AR.2 Predicted to enable protein-disulfide reductase activity. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in male infertility. Is an ortholog of human TXNDC8 (thioredoxin domain containing 8). WB:WBGene00021934 cct-8 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Is an ortholog of human CCT8 (chaperonin containing TCP1 subunit 8). WB:WBGene00021935 mrpl-46 Predicted to be a structural constituent of ribosome. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL46 (mitochondrial ribosomal protein L46). WB:WBGene00021936 zipt-15 Predicted to enable monoatomic cation:bicarbonate symporter activity and zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion import across plasma membrane. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIn and hypermanganesemia with dystonia 2. Is an ortholog of human SLC39A14 (solute carrier family 39 member 14) and SLC39A8 (solute carrier family 39 member 8). WB:WBGene00021938 Y55F3BR.1 Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and exonuclease activity. Is an ortholog of human DDX1 (DEAD-box helicase 1). WB:WBGene00021939 Y55F3BR.2 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00021941 lgc-33 Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00021942 madf-1 Predicted to enable DNA binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00021943 Y55F3BR.6 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in body wall musculature. WB:WBGene00021945 lem-4 Enables protein phosphatase 2A binding activity. Involved in mitotic nuclear membrane reassembly; negative regulation of phosphorylation; and positive regulation of protein dephosphorylation. Located in nuclear envelope. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 16. Is an ortholog of human ANKLE2 (ankyrin repeat and LEM domain containing 2). WB:WBGene00021947 srt-23 Predicted to be located in membrane. WB:WBGene00021948 kvs-5 Predicted to enable delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Located in plasma membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26. Is an ortholog of human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1). WB:WBGene00021949 clec-164 Enriched in amphid sheath cell; ciliated neurons; and in male based on RNA-seq studies. Is affected by several genes including aak-2; drh-3; and smg-2 based on tiling array; microarray; and RNA-seq studies. Is affected by fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00021950 cutl-26 Predicted to be located in membrane. WB:WBGene00021951 srt-24 Predicted to be located in membrane. WB:WBGene00021952 vha-19 Involved in intracellular water homeostasis; positive regulation of oocyte development; and positive regulation of protein targeting to membrane. Located in membrane raft. Expressed in excretory canal; hypodermis; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in immunodeficiency 47. Is an ortholog of human ATP6AP1 (ATPase H+ transporting accessory protein 1) and ATP6AP1L (ATPase H+ transporting accessory protein 1 like (pseudogene)). WB:WBGene00021953 Y55H10A.2 Predicted to be located in membrane. WB:WBGene00021954 Y55H10B.1 No description available WB:WBGene00021955 Y55H10B.2 No description available WB:WBGene00021956 Y57E12AL.1 Predicted to be located in membrane. Is an ortholog of human SERINC1 (serine incorporator 1) and SERINC3 (serine incorporator 3). WB:WBGene00021957 Y57E12AL.2 Enriched in AVJL and AVJR based on single-cell RNA-seq studies. Is affected by jmjd-3.1; drh-3; and ikb-1 based on RNA-seq studies. Is affected by five chemicals including Atrazine; Chlorpyrifos; and Colistin based on microarray studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF4473. WB:WBGene00021958 spig-8 Is affected by several genes including eat-2; mec-8; and bet-1 based on RNA-seq studies. Is affected by four chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF4473. WB:WBGene00021959 Y57E12AL.6 Predicted to be involved in proteasome assembly. Predicted to be located in cytoplasm and nucleus. WB:WBGene00021960 tmem-258 Predicted to be involved in protein N-linked glycosylation. Predicted to be located in several cellular components, including cytoplasm; membrane; and membrane-bounded organelle. Predicted to be part of oligosaccharyltransferase I complex. Is an ortholog of human TMEM258 (transmembrane protein 258). WB:WBGene00021961 Y57E12B.1 Is affected by several genes including clk-1; lin-35; and lin-15B based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Ag nanoparticles; and single-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00021963 lipl-6 Predicted to be involved in lipid metabolic process. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). WB:WBGene00021964 Y57E12B.4 Enriched in dopaminergic neurons and muscle cell based on tiling array and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and nanoparticle based on microarray and RNA-seq studies. WB:WBGene00021965 Y57G7A.1 Enriched in GABAergic neurons; amphid sheath cell; excretory cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including rotenone; mianserin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00021966 Y57G7A.2 Enriched in ABalpppapa; ABplapaaaa; ABpraaaapa; and ABprapaaaa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including Mercuric Chloride; rotenone; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00021967 Y57G7A.3 Predicted to be located in membrane. WB:WBGene00021968 Y57G7A.5 Enriched in I5 neuron; cholinergic neurons; germ line; retrovesicular ganglion; and in male based on proteomic; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00021969 Y57G7A.6 Predicted to be located in membrane. Expressed in hypodermis. WB:WBGene00021970 srz-64 Predicted to be located in membrane. WB:WBGene00021971 Y57G7A.8 Is affected by several genes including daf-16; daf-2; and glp-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021972 glb-31 Predicted to enable heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Expressed in head neurons. WB:WBGene00021973 emc-2 Located in sarcoplasmic reticulum. Is an ortholog of human EMC2 (ER membrane protein complex subunit 2). WB:WBGene00021974 Y57G7A.11 Enriched in anal depressor muscle; body wall muscle cell; dopaminergic neurons; intestinal muscle; and tail hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including elt-2; mex-3; and set-2 based on microarray and RNA-seq studies. Is affected by six chemicals including aldicarb; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00021975 Y58A7A.1 Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in copper ion transmembrane transport and intracellular copper ion homeostasis. Predicted to be located in late endosome membrane. Is an ortholog of human SLC31A1 (solute carrier family 31 member 1). WB:WBGene00021976 Y58A7A.2 Enriched in several structures, including ABarpaapap; ABarpaappa; anterior hypodermis; arc ant V; and excretory system based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by twelve chemicals including methylmercury hydroxide; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00021977 Y58A7A.3 Predicted to enable zinc ion binding activity. WB:WBGene00021978 Y58A7A.4 Predicted to enable zinc ion binding activity. Expressed in head neurons and intestine. WB:WBGene00021979 Y58A7A.5 Acts upstream of or within PERK-mediated unfolded protein response. WB:WBGene00021980 glb-32 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in head neurons; lateral nerve cord; tail neurons; ventral cord neurons; and ventral nerve cord. WB:WBGene00021981 lgc-26 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in determination of adult lifespan and endocytosis. Located in cytoplasm. WB:WBGene00021982 Y58G8A.2 No description available WB:WBGene00021983 npr-5 Predicted to enable neuropeptide binding activity and neuropeptide receptor activity. Involved in regulation of muscle contraction. Predicted to be located in neuron projection and plasma membrane. Expressed in body wall musculature; chemosensory neurons; and head neurons. Human ortholog(s) of this gene implicated in hypertension. Is an ortholog of human PRLHR (prolactin releasing hormone receptor). WB:WBGene00021984 Y59C2A.1 Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Is an ortholog of human CPA6 (carboxypeptidase A6). WB:WBGene00021985 Y59C2A.2 Predicted to be located in membrane. Expressed in head and tail. WB:WBGene00021986 Y59C2A.3 Enriched in ABalppppppa; ABpraaapppa; OLL; germ line; and interneuron based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by eight chemicals including aldicarb; 1-methylnicotinamide; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00021987 fbxa-40 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by fluoranthene; Chlorpyrifos; and Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00021988 rgs-8.2 Is affected by several genes including daf-16; dpy-10; and gld-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Human RGS1 enables G-protein alpha-subunit binding activity and GTPase activator activity. Is predicted to encode a protein with the following domains: RGS, subdomain 1/3; RGS, subdomain 2; RGS domain superfamily; Regulator of G protein signaling domain; and RGS domain. Is an ortholog of human RGS1 (regulator of G protein signaling 1). WB:WBGene00021989 Y59E1A.3 No description available WB:WBGene00021990 Y59E1B.1 Enriched in several structures, including AFD; Z1.p; Z4.a; male distal tip cell; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00021992 thn-6 Predicted to be located in extracellular region. WB:WBGene00021993 nsph-4.2 Enriched in several structures, including I5 neuron; MSaapaapa; amphid sheath cell; cholinergic neurons; and sperm based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cytosolic motility protein. WB:WBGene00021994 Y59E9AL.4 Predicted to enable L-ascorbic acid transmembrane transporter activity. Predicted to be involved in L-ascorbic acid transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC23A1 (solute carrier family 23 member 1) and SLC23A2 (solute carrier family 23 member 2). WB:WBGene00021995 Y59E9AL.5 Is affected by several genes including daf-2; dpy-10; and sir-2.1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including multi-walled carbon nanotube; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00021996 cylc-1 Enriched in several structures, including body wall muscle cell; cholinergic neurons; germ line; hypodermis; and sperm based on proteomic; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty-eight chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq; microarray; and proteomic studies. WB:WBGene00021997 Y59E9AR.1 Predicted to be located in cytoskeleton. WB:WBGene00021998 Y59E9AR.2 Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleus. WB:WBGene00021999 thn-5 Predicted to be located in extracellular region. WB:WBGene00022000 tbx-42 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00022001 thn-7 Is affected by cyc-1; ets-4; and eat-2 based on microarray studies. Is affected by methylmercuric chloride and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00022002 Y59E9AR.7 Expressed in germ line. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00022003 Y59E9AR.8 Is affected by several genes including daf-16; skn-1; and sek-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Zc3h12a-like Ribonuclease NYN domain and Ribonuclease Zc3h12a-like, NYN domain. WB:WBGene00022004 npr-22 Enables neuropeptide receptor activity. Involved in several processes, including determination of adult lifespan; negative regulation of feeding behavior; and positive regulation of egg-laying behavior. Predicted to be located in plasma membrane. Expressed in head muscle; intestine; neurons; and pharyngeal muscle cell. WB:WBGene00022005 Y59H11AM.1 Predicted to be located in cytoskeleton. WB:WBGene00022006 mpst-5 Predicted to enable thiosulfate sulfurtransferase activity. Predicted to be located in mitochondrion. Is an ortholog of human MPST (mercaptopyruvate sulfurtransferase). WB:WBGene00022007 mpst-6 Predicted to enable sulfurtransferase activity. Is an ortholog of human MPST (mercaptopyruvate sulfurtransferase). WB:WBGene00022008 Y59H11AM.4 Enriched in amphid sheath cell; head mesodermal cell; and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00022010 catp-7 Predicted to enable ATPase-coupled monoatomic cation transmembrane transporter activity and polyamine transmembrane transporter activity. Predicted to be involved in intracellular calcium ion homeostasis and polyamine transmembrane transport. Predicted to be located in membrane. Expressed in several structures, including amphid neurons; excretory cell; gonad; spermatocyte; and vulva. Human ortholog(s) of this gene implicated in Kufor-Rakeb syndrome; hereditary spastic paraplegia 78; and primary pulmonary hypertension. Is an ortholog of human ATP13A3 (ATPase 13A3). WB:WBGene00022011 Y59H11AR.3 Is affected by drh-3; set-2; and etr-1 based on RNA-seq studies. Is predicted to encode a protein with the following domains: Transthyretin-like superfamily; Protein of unknown function DUF870, Caenorhabditis species; and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00022012 Y59H11AR.4 Predicted to be located in membrane. WB:WBGene00022013 Y60C6A.1 Predicted to be located in membrane. WB:WBGene00022014 Y61A9LA.1 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. Expressed in hypodermis. WB:WBGene00022015 Y61A9LA.3 Enriched in germ line; hypodermis; and neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-2; sir-2.1; and fbf-1 based on microarray and RNA-seq studies. Is affected by resveratrol; Sirolimus; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022016 Y61A9LA.4 Is affected by several genes including daf-16; daf-2; and daf-18 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022017 Y61A9LA.5 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00022018 Y61A9LA.7 Enriched in several structures, including RIM; anterior arcade cell; coelomocyte; head mesodermal cell; and pharyngeal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by nine chemicals including mianserin; Alovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00022019 sut-2 Predicted to enable poly(A) binding activity. Predicted to be involved in negative regulation of mRNA polyadenylation and regulation of mRNA stability. Located in nucleus and perinuclear region of cytoplasm. Expressed in germ line; hypodermis; and intestine. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 56. Is an ortholog of human ZC3H14 (zinc finger CCCH-type containing 14). WB:WBGene00022020 hpo-39 Enriched in several structures, including ABalppppapa; ABpraaapapa; I5 neuron; OLQ; and cholinergic neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including pie-1; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022021 Y61A9LA.10 Predicted to enable GTP binding activity; GTPase activity; and U3 snoRNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of 90S preribosome. Expressed in head. Human ortholog(s) of this gene implicated in nonsyndromic aplasia cutis congenita. Is an ortholog of human BMS1 (BMS1 ribosome biogenesis factor). WB:WBGene00022022 txt-6 Enriched in AFD; germ line; hypodermis; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; pgl-1; and isp-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; bisphenol S; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1757 and Protein of unknown function (DUF1757). WB:WBGene00022023 Y64H9A.1 Enriched in intestine based on microarray studies. Is affected by several genes including daf-16; clk-1; and drh-3 based on microarray and RNA-seq studies. Is affected by Diazinon based on microarray studies. WB:WBGene00022024 Y64H9A.2 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00022025 cus-2 Predicted to enable RNA binding activity. Predicted to be part of U2 snRNP and U2-type spliceosomal complex. Is an ortholog of human HTATSF1 (HIV-1 Tat specific factor 1). WB:WBGene00022026 Y65B4A.2 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. WB:WBGene00022027 vps-20 Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and vesicle budding from membrane. Predicted to be located in multivesicular body. Predicted to be part of ESCRT III complex. Is an ortholog of human CHMP6 (charged multivesicular body protein 6). WB:WBGene00022028 Y65B4A.4 Enriched in intestine based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and lin-15B based on microarray and RNA-seq studies. Is affected by eight chemicals including D-glucopyranose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022029 eif-4A3 Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be involved in translational initiation. Predicted to be located in nucleolus. Predicted to be part of catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in intellectual disability and pancreatic cancer. Is an ortholog of human EIF4A3 (eukaryotic translation initiation factor 4A3). WB:WBGene00022030 Y65B4A.7 Predicted to enable metal ion binding activity. WB:WBGene00022031 Y65B4A.8 Predicted to enable dephospho-CoA kinase activity. Predicted to be involved in coenzyme A biosynthetic process. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III; neurodegeneration with brain iron accumulation 6; and pontocerebellar hypoplasia type 12. Is an ortholog of human COASY (Coenzyme A synthase). WB:WBGene00022032 Y65B4A.9 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00022033 Y65B4BL.1 Enriched in hypodermis; sensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00022034 deps-1 Predicted to be involved in regulatory ncRNA-mediated gene silencing. Located in P granule. Expressed in germ line and oocyte. WB:WBGene00022035 Y65B4BL.3 Predicted to be located in membrane. WB:WBGene00022036 Y65B4BL.4 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00022037 acs-13 Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in long-chain fatty acid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Expressed in head. Human ortholog(s) of this gene implicated in acute myeloid leukemia; congenital diarrhea; and obesity. Is an ortholog of human ACSL1 (acyl-CoA synthetase long chain family member 1); ACSL5 (acyl-CoA synthetase long chain family member 5); and ACSL6 (acyl-CoA synthetase long chain family member 6). WB:WBGene00022038 Y65B4BL.6 Enriched in anterior hypodermis; arc ant V; rectal epithelial cell; and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including Ethanol; tryptophan; and 1-methylnicotinamide based on RNA-seq and microarray studies. WB:WBGene00022039 Y65B4BL.7 Predicted to be located in membrane. WB:WBGene00022040 Y65B4BR.1 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Is an ortholog of human PLB1 (phospholipase B1). WB:WBGene00022042 icd-2 Predicted to enable unfolded protein binding activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in cytoplasm. Predicted to be part of nascent polypeptide-associated complex. Expressed in intestinal cell. Is an ortholog of human NACA4P (NACA family member 4, pseudogene). WB:WBGene00022043 psf-3 Predicted to be involved in mitotic DNA replication initiation. Predicted to be located in nucleus. Predicted to be part of GINS complex. Is an ortholog of human GINS3 (GINS complex subunit 3). WB:WBGene00022044 dpm-1 Predicted to enable dolichyl-phosphate beta-D-mannosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ie. Is an ortholog of human DPM1 (dolichyl-phosphate mannosyltransferase subunit 1, catalytic). WB:WBGene00022045 mrpl-55 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is an ortholog of human MRPL55 (mitochondrial ribosomal protein L55). WB:WBGene00022046 garr-1 Predicted to enable box H/ACA snoRNA binding activity. Predicted to be involved in snoRNA guided rRNA pseudouridine synthesis. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex. Is an ortholog of human GAR1 (GAR1 ribonucleoprotein). WB:WBGene00022047 Y66H1A.5 Enriched in head mesodermal cell and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; mianserin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00022048 fln-1 Predicted to enable actin filament binding activity. Involved in several processes, including axon development; semaphorin-plexin signaling pathway; and uterus morphogenesis. Located in actin filament. Expressed in body wall musculature; gonad; hypodermis; intestine; and vulval muscle. Human ortholog(s) of this gene implicated in several diseases, including X-linked recessive disease (multiple); bone development disease (multiple); distal muscular dystrophy 4; and heart valve disease (multiple). Is an ortholog of human FLNB (filamin B) and FLNC (filamin C). WB:WBGene00022051 rep-1 Predicted to enable GTPase activator activity and Rab GDP-dissociation inhibitor activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in cytosol and nucleus. Predicted to be part of Rab-protein geranylgeranyltransferase complex. Expressed in alimentary muscle; body wall musculature; hypodermis; and neurons. Human ortholog(s) of this gene implicated in asthma and choroideremia. Is an ortholog of human CHM (CHM Rab escort protein) and CHML (CHM like Rab escort protein). WB:WBGene00022052 Y67D2.2 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Is an ortholog of human USP30 (ubiquitin specific peptidase 30). WB:WBGene00022053 cisd-3.2 Predicted to enable 2 iron, 2 sulfur cluster binding activity. Predicted to be involved in protein maturation by [2Fe-2S] cluster transfer. Predicted to be located in mitochondrion. Is an ortholog of human CISD3 (CDGSH iron sulfur domain 3). WB:WBGene00022054 mtg-1 Predicted to enable GTPase activity. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion. Is an ortholog of human MTG1 (mitochondrial ribosome associated GTPase 1). WB:WBGene00022055 Y67D2.5 Predicted to enable N-acetyltransferase activity. Is an ortholog of human NAT9 (N-acetyltransferase 9 (putative)). WB:WBGene00022056 ddx-35 Predicted to enable RNA binding activity and helicase activity. Predicted to be part of catalytic step 2 spliceosome. Is an ortholog of human DHX35 (DEAH-box helicase 35). WB:WBGene00022057 eelo-1 Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of human SAP30BP (SAP30 binding protein). WB:WBGene00022059 Y67D8A.2 Predicted to enable calmodulin binding activity. Predicted to be involved in glycogen metabolic process. Predicted to be located in plasma membrane. Predicted to be part of phosphorylase kinase complex. Human ortholog(s) of this gene implicated in glycogen storage disease IXb. Is an ortholog of human PHKB (phosphorylase kinase regulatory subunit beta). WB:WBGene00022060 dmd-9 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to be located in nucleus. Expressed in several structures, including body wall musculature; coelomocyte; intestine; neurons; and somatic nervous system. Is an ortholog of human DMRTB1 (DMRT like family B with proline rich C-terminal 1); DMRTC1 (DMRT like family C1); and DMRTC1B (DMRT like family C1B). WB:WBGene00022061 Y67D8B.1 Predicted to enable metal ion binding activity. WB:WBGene00022062 Y67D8B.2 Predicted to be located in nucleus. WB:WBGene00022063 nlp-81 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00022064 Y67D8B.5 Predicted to be located in membrane. WB:WBGene00022066 Y67D8C.2 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. Is affected by five chemicals including aldicarb; Rifampin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00022067 ivph-3 Predicted to be involved in negative regulation of vulval development. WB:WBGene00022069 eel-1 Predicted to enable ubiquitin protein ligase activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; hemidesmosome assembly; and signal transduction in response to DNA damage. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including hermaphrodite gonad; intestine; neurons; pharynx; and vulva. Used to study syndromic X-linked intellectual disability. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Turner type. Is an ortholog of human HUWE1 (HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1). WB:WBGene00022070 Y67D8C.6 Predicted to be located in membrane. WB:WBGene00022071 Y67D8C.7 Enriched in male-specific anatomical entity based on microarray studies. Is affected by several genes including rrf-3; eat-2; and csr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube; cadmium; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022072 cpg-9 Enriched in ABplpappaa; ALA; M cell; excretory cell; and muscle cell based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including rotenone; Tunicamycin; and D-glucopyranose based on RNA-seq and microarray studies. WB:WBGene00022073 Y67D8C.9 Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Involved in embryo development; regulation of egg-laying behavior; and regulation of meiotic cell cycle process involved in oocyte maturation. Predicted to be located in cytoplasm. WB:WBGene00022074 Y69A2AR.1 Enriched in ABplpaaaap; ABprpaaaap; germ line; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and npr-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Aspirin; Zidovudine; and Rifampin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022075 nduv-3 Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. WB:WBGene00022076 daao-1 Enables D-amino-acid oxidase activity. Involved in obsolete oxidation-reduction process. Predicted to be located in cytoplasm. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human DDO (D-aspartate oxidase). WB:WBGene00022077 vamp-7 Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in vesicle fusion. Predicted to be located in plasma membrane. Predicted to be part of SNARE complex. Is an ortholog of human VAMP8 (vesicle associated membrane protein 8). WB:WBGene00022078 epg-9 Enables protein kinase binding activity. Involved in aggrephagy. Predicted to be located in phagophore assembly site. Expressed in several structures, including body wall musculature; head; hypodermis; pharyngeal muscle cell; and tail. Human ortholog(s) of this gene implicated in cholangiocarcinoma; colon cancer; and hepatocellular carcinoma. Is an ortholog of human ATG101 (autophagy related 101). WB:WBGene00022079 Y69A2AR.8 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00022081 Y69A2AR.10 No description available WB:WBGene00022082 Y69A2AR.11 Is affected by several genes including rrf-3; eat-2; and unc-30 based on microarray and RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00022083 Y69A2AR.12 Predicted to be located in membrane. WB:WBGene00022085 Y69A2AR.14 Enriched in intestine and in male based on RNA-seq and microarray studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray; RNA-seq; and tiling array studies. Is affected by fourteen chemicals including hydrogen sulfide; Ethanol; and tryptophan based on microarray and RNA-seq studies. WB:WBGene00022086 sprr-3 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00022087 Y69A2AR.16 Predicted to enable nuclear export signal receptor activity. Predicted to be involved in protein export from nucleus. Predicted to be located in cytoplasm. Predicted to be part of nuclear pore. Is an ortholog of human XPO4 (exportin 4). WB:WBGene00022089 Y69A2AR.18 Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1). Expressed in tail. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human ATP5F1C (ATP synthase F1 subunit gamma). WB:WBGene00022090 Y69A2AR.19 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00022091 Y69A2AR.20 No description available WB:WBGene00022092 ccdc-12 Predicted to be part of U2-type spliceosomal complex and post-mRNA release spliceosomal complex. Is an ortholog of human CCDC12 (coiled-coil domain containing 12). WB:WBGene00022093 Y69A2AR.22 Enriched in amphid sheath cell; arc ant V; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022094 Y69A2AR.23 Predicted to be located in membrane. WB:WBGene00022095 Y69A2AR.24 Enriched in hypodermis and pharyngeal muscle cell based on tiling array studies. Is affected by several genes including daf-2; sir-2.1; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by tryptophan; indole; and resveratrol based on microarray studies. WB:WBGene00022096 Y69A2AR.25 Enriched in AFD; ASER; and intestine based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray; quantitative PCR; and RNA-seq studies. Is affected by twenty chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00022097 nhr-242 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00022099 Y69A2AR.28 Enriched in several structures, including GLR; ciliated neurons; germ line; head mesodermal cell; and male distal tip cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including aldicarb; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spo12 family and Spo12. WB:WBGene00022100 Y69A2AR.31 Predicted to enable signaling receptor activity. Predicted to be involved in nervous system development. Predicted to be located in external side of plasma membrane. Predicted to be part of receptor complex. Is an ortholog of human GFRA4 (GDNF family receptor alpha 4) and GFRAL (GDNF family receptor alpha like). WB:WBGene00022101 Y69A2AR.32 Predicted to enable mRNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. WB:WBGene00022102 Y69F12A.1 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Is an ortholog of human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). WB:WBGene00022103 cdh-12 Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane. WB:WBGene00022104 acsd-1 Predicted to enable aminocarboxymuconate-semialdehyde decarboxylase activity. Predicted to be involved in negative regulation of quinolinate biosynthetic process and secondary metabolic process. Predicted to be located in cytosol. Is an ortholog of human ACMSD (aminocarboxymuconate semialdehyde decarboxylase). WB:WBGene00022105 Y71D11A.4 No description available WB:WBGene00022106 lgc-46 Predicted to enable transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in body wall musculature; nervous system; and pharyngeal muscle cell. WB:WBGene00022107 Y71F9AL.1 Predicted to enable tRNA (guanine-N2-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to be located in cytoplasm. Is an ortholog of human TRMT11 (tRNA methyltransferase 11 homolog). WB:WBGene00022108 Y71F9AL.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00022109 Y71F9AL.3 No description available WB:WBGene00022110 pph-7 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00022111 Y71F9AL.6 Predicted to be located in membrane. WB:WBGene00022112 Y71F9AL.7 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalaapppa; ABalapaaaa; and ciliated neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00022113 Y71F9AL.8 Enriched in several structures, including NSM; cephalic sheath cell; g1; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including stavudine; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00022114 Y71F9AL.9 Enriched in anal depressor muscle; germ line; hermaphrodite distal tip cell; intestine; and male distal tip cell based on proteomic; Chronogram; and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and sir-2.1 based on microarray; RNA-seq; proteomic; and tiling array studies. Is affected by eight chemicals including silicon dioxide nanoparticle; paraquat; and Atrazine based on microarray and RNA-seq studies. Human SPATS2L enables RNA binding activity. Is predicted to encode a protein with the following domains: UBA-like superfamily; SPATS2-like; and Phosphorylation site. Is an ortholog of human SPATS2L (spermatogenesis associated serine rich 2 like). WB:WBGene00022115 Y71F9AL.10 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm; intracellular membrane-bounded organelle; and membrane. Is an ortholog of human ZNRF1 (zinc and ring finger 1) and ZNRF2 (zinc and ring finger 2). WB:WBGene00022117 Y71F9AL.12 Enriched in MSaapapa; MSpaaapa; MSpapapa; germ line; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by five chemicals including rotenone; antimycin; and paraquat based on RNA-seq and microarray studies. WB:WBGene00022118 dnc-5 Part of dynactin complex. Is an ortholog of human DCTN5 (dynactin subunit 5). WB:WBGene00022119 copa-1 Predicted to enable structural molecule activity. Predicted to be involved in Golgi vesicle transport and intracellular protein transport. Predicted to be located in Golgi membrane. Predicted to be part of COPI vesicle coat. Expressed in distal tip cell and head. Human ortholog(s) of this gene implicated in autoimmune interstitial lung, joint, and kidney disease. Is an ortholog of human COPA (COPI coat complex subunit alpha). WB:WBGene00022121 cogc-3 Involved in gonad morphogenesis and regulation of cell migration. Located in Golgi apparatus and endoplasmic reticulum. Expressed in intestine; pharynx; seam cell; and vulva. Is an ortholog of human COG3 (component of oligomeric golgi complex 3). WB:WBGene00022122 trap-1 Predicted to be located in endoplasmic reticulum. Is an ortholog of human SSR1 (signal sequence receptor subunit 1). WB:WBGene00022123 Y71F9AR.2 Predicted to enable GTP binding activity and GTPase activity. Is an ortholog of human RASL12 (RAS like family 12). WB:WBGene00022124 supr-1 Located in axon; cytoplasm; and nucleus. WB:WBGene00022125 Y71F9B.1 Predicted to be located in membrane. WB:WBGene00022126 Y71F9B.2 Predicted to enable phosphatidate cytidylyltransferase activity. Predicted to be involved in CDP-diacylglycerol biosynthetic process and cardiolipin biosynthetic process. Predicted to be located in mitochondrion. Predicted to be extrinsic component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 56. Is an ortholog of human TAMM41 (TAM41 mitochondrial translocator assembly and maintenance homolog). WB:WBGene00022127 yop-1 Located in cortical endoplasmic reticulum. Expressed in head and tail. Human ortholog(s) of this gene implicated in retinitis pigmentosa 77. Is an ortholog of human REEP5 (receptor accessory protein 5) and REEP6 (receptor accessory protein 6). WB:WBGene00022128 Y71F9B.6 Predicted to be involved in regulation of cell cycle. Is an ortholog of human CABLES1 (Cdk5 and Abl enzyme substrate 1). WB:WBGene00022129 lron-11 Predicted to be located in membrane. Expressed in hypodermis; muscle cell; and pharynx. Is an ortholog of human CPN2 (carboxypeptidase N subunit 2). WB:WBGene00022130 Y71F9B.9 Predicted to enable L-gulonate 3-dehydrogenase activity. Predicted to be involved in fatty acid metabolic process. Is an ortholog of human CRYL1 (crystallin lambda 1). WB:WBGene00022131 Y71F9B.13 Enriched in germ line; head ganglion; hypodermis; and muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; D-glucose; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00022133 Y71F9B.15 Predicted to be located in membrane. WB:WBGene00022134 hrpu-2 Enriched in AVK based on RNA-seq studies. Is affected by several genes including daf-2; clk-1; and aak-2 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including rotenone; stavudine; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022138 trpp-10 Predicted to be involved in early endosome to Golgi transport and intra-Golgi vesicle-mediated transport. Predicted to be located in cytosol. Predicted to be part of TRAPPII protein complex. Is an ortholog of human TRAPPC10 (trafficking protein particle complex subunit 10). WB:WBGene00022139 tub-2 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABplapppaa; head mesodermal cell; and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by seven chemicals including rotenone; Rifampin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Tubby-like, C-terminal; Tubby, C-terminal; and Tub family. Is an ortholog of human TULP4 (TUB like protein 4). WB:WBGene00022140 Y71G12A.4 Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to be located in endosome membrane and plasma membrane. WB:WBGene00022141 chaf-2 Predicted to be involved in nucleosome assembly. Predicted to be located in nucleus. Predicted to be part of CAF-1 complex. Human ortholog(s) of this gene implicated in several diseases, including glioblastoma; oral squamous cell carcinoma; and skin melanoma. Is an ortholog of human CHAF1B (chromatin assembly factor 1 subunit B). WB:WBGene00022142 Y71G12B.2 Enriched in intestine based on tiling array studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on RNA-seq; microarray; and proteomic studies. Is affected by twelve chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: F-box protein she-1-like. WB:WBGene00022143 Y71G12B.3 Predicted to be located in membrane. WB:WBGene00022144 pghm-1 Predicted to enable copper ion binding activity and peptidylglycine monooxygenase activity. Predicted to be involved in peptide metabolic process. Predicted to be located in extracellular region and membrane. Expressed in head ganglion; nervous system; and tail ganglion. WB:WBGene00022145 Y71G12B.5 Enriched in AFD; AVK; neurons; and in male based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domain: NTF2-like domain superfamily. WB:WBGene00022146 rml-5 Predicted to be involved in small molecule metabolic process. WB:WBGene00022148 ddx-27 Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Predicted to be located in nucleolus. Is an ortholog of human DDX27 (DEAD-box helicase 27). WB:WBGene00022149 lin-65 Involved in chromatin remodeling and mitochondrial unfolded protein response. Located in cytosol and nucleus. Expressed in head neurons and intestine. WB:WBGene00022150 Y71G12B.10 Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in ketone body biosynthetic process and leucine catabolic process. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1). WB:WBGene00022152 atg-5 Predicted to contribute to Atg8-family ligase activity. Involved in autophagosome assembly and regulation of autophagy. Predicted to be located in phagophore assembly site membrane. Predicted to be part of Atg12-Atg5-Atg16 complex. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 25. Is an ortholog of human ATG5 (autophagy related 5). WB:WBGene00022153 Y71G12B.13 Enriched in several structures, including ABalappaap; ABalppappa; AVK; PLM; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and clk-1 based on RNA-seq; tiling array; and microarray studies. Is affected by four chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022154 drag-1 Predicted to enable coreceptor activity. Involved in several processes, including mesodermal cell fate specification; regulation of BMP signaling pathway; and regulation of dauer larval development. Located in plasma membrane. Part of receptor complex. Expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in hemochromatosis type 2A and multiple sclerosis. Is an ortholog of human HJV (hemojuvelin BMP co-receptor) and RGMA (repulsive guidance molecule BMP co-receptor a). WB:WBGene00022155 Y71G12B.17 Predicted to enable phospholipid binding activity and phospholipid transporter activity. Predicted to be involved in intermembrane lipid transfer and phospholipid transport. Predicted to be located in cytoplasm. Is an ortholog of human PITPNA (phosphatidylinositol transfer protein alpha) and PITPNB (phosphatidylinositol transfer protein beta). WB:WBGene00022156 Y71G12B.18 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00022157 Y71G12B.22 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00022158 Y71G12B.23 Predicted to enable electron transfer activity. Predicted to be involved in electron transport chain. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Is an ortholog of human MMD (monocyte to macrophage differentiation associated) and MMD2 (monocyte to macrophage differentiation associated 2). WB:WBGene00022159 mppa-1 Contributes to metalloendopeptidase activity. Involved in proteolysis. Part of mitochondrial processing peptidase complex. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 2. Is an ortholog of human PMPCA (peptidase, mitochondrial processing subunit alpha). WB:WBGene00022160 Y71G12B.25 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in brush border membrane. WB:WBGene00022161 mtig-1 Predicted to be located in nuclear envelope. WB:WBGene00022162 Y71G12B.27 Predicted to enable several functions, including cyclin-dependent protein serine/threonine kinase activator activity; histone binding activity; and ubiquitin binding activity. Predicted to be involved in regulation of mitotic cell cycle. Predicted to be part of SCF ubiquitin ligase complex and cyclin-dependent protein kinase holoenzyme complex. Is an ortholog of human CKS2 (CDC28 protein kinase regulatory subunit 2). WB:WBGene00022163 Y71G12B.28 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; metformin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00022165 Y71H2AL.2 Predicted to be located in membrane. WB:WBGene00022166 Y71H2AM.1 Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to be located in cytoplasm. Predicted to be part of EKC/KEOPS complex. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 3. Is an ortholog of human OSGEP (O-sialoglycoprotein endopeptidase). WB:WBGene00022167 pipp-4P Predicted to enable phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be located in bounding membrane of organelle and plasma membrane. Is an ortholog of human PIP4P1 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1) and PIP4P2 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2). WB:WBGene00022168 Y71H2AM.3 Predicted to enable cyclin binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human UBE3D (ubiquitin protein ligase E3D). WB:WBGene00022169 nduc-2 Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Is an ortholog of human NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2) and NDUFC2-KCTD14 (NDUFC2-KCTD14 readthrough). WB:WBGene00022170 cox-6B Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX6B1 (cytochrome c oxidase subunit 6B1). WB:WBGene00022171 Y71H2AM.6 Predicted to enable phosphopantothenate--cysteine ligase activity. Predicted to be involved in coenzyme A biosynthetic process. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2C. Is an ortholog of human PPCS (phosphopantothenoylcysteine synthetase). WB:WBGene00022172 cosa-1 Involved in reciprocal meiotic recombination. Located in site of double-strand break. Is an ortholog of human CNTD1 (cyclin N-terminal domain containing 1). WB:WBGene00022173 set-27 Predicted to enable histone H3K36 methyltransferase activity; histone H3K4 methyltransferase activity; and transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Expressed in muscle cell. Is an ortholog of human SETD3 (SET domain containing 3, actin N3(tau)-histidine methyltransferase). WB:WBGene00022174 slc-30A9 Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion transport. Predicted to be located in endoplasmic reticulum. Is an ortholog of human SLC30A9 (solute carrier family 30 member 9). WB:WBGene00022175 tmem-132 Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 99. Is an ortholog of human TMEM132B (transmembrane protein 132B). WB:WBGene00022176 Y71H2AM.11 Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Human ortholog(s) of this gene implicated in glomerulonephritis. Is an ortholog of human CNDP2 (carnosine dipeptidase 2). WB:WBGene00022177 Y71H2AM.12 Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including cell chemotaxis; cellular component organization; and regulation of cell shape. Predicted to be located in several cellular components, including cytoplasmic vesicle; cytoskeleton; and plasma membrane. WB:WBGene00022178 cest-25 Enriched in several structures, including dopaminergic neurons; excretory cell; mc2; mechanosensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eleven chemicals including D-glucose; Sodium Chloride; and Rifampin based on RNA-seq; microarray; and proteomic studies. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Human CES1 enables carboxylesterase activity and sterol esterase activity. Is predicted to encode a protein with the following domains: Carboxylesterase family; Carboxylesterase, type B; and Alpha/Beta hydrolase fold. Is an ortholog of human CES1 (carboxylesterase 1). WB:WBGene00022179 Y71H2AM.14 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00022180 gldi-9 Located in cell junction and striated muscle dense body. Is an ortholog of human KIAA1217 (KIAA1217) and SRCIN1 (SRC kinase signaling inhibitor 1). WB:WBGene00022181 pho-9 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J. Is an ortholog of human ACP2 (acid phosphatase 2, lysosomal) and ACP4 (acid phosphatase 4). WB:WBGene00022182 swsn-3 Predicted to enable nuclear receptor binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of SWI/SNF complex. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 5 and familial meningioma. Is an ortholog of human SMARCE1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1). WB:WBGene00022185 Y71H2AM.20 Predicted to enable peptidyl-prolyl cis-trans isomerase activity and protein tyrosine phosphatase activator activity. Predicted to be involved in mitotic spindle organization. Predicted to be located in cytoplasm and nucleus. Predicted to be part of protein phosphatase type 2A complex. Is an ortholog of human PTPA (protein phosphatase 2 phosphatase activator). WB:WBGene00022188 txdc-17 Predicted to enable protein-disulfide reductase (NAD(P)) activity. Predicted to be located in cytosol. Is an ortholog of human TXNDC17 (thioredoxin domain containing 17). WB:WBGene00022189 Y71H2AR.2 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; cerebrovascular disease (multiple); and pycnodysostosis. Is an ortholog of human CTSK (cathepsin K) and CTSS (cathepsin S). WB:WBGene00022190 josd-1 Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in proteolysis. Is an ortholog of human JOSD1 (Josephin domain containing 1). WB:WBGene00022191 acbp-8 Predicted to enable fatty-acyl-CoA binding activity. WB:WBGene00022192 Y71H2B.2 Predicted to enable RNA binding activity. Predicted to be involved in snRNA export from nucleus. Predicted to be located in nucleus. Is an ortholog of human PHAX (phosphorylated adaptor for RNA export). WB:WBGene00022193 ppfr-4 Predicted to enable protein phosphatase 2A binding activity and protein phosphatase regulator activity. Involved in embryo development and protein localization to basolateral plasma membrane. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Is an ortholog of human IGBP1 (immunoglobulin binding protein 1) and IGBP1C (IGBP1 family member C). WB:WBGene00022194 Y71H2B.4 Enriched in muscle cell and neurons based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; rotenone; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00022195 Y71H2B.5 Predicted to enable tRNA binding activity. Predicted to be involved in tRNA modification. WB:WBGene00022196 gpa-17 Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-activating dopamine receptor signaling pathway and sensory perception of chemical stimulus. Predicted to be part of heterotrimeric G-protein complex. WB:WBGene00022197 Y71H2B.8 Enriched in AVA; RMED; coelomocyte; muscle cell; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; hsf-1; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00022198 Y71H2B.11 Enriched in ABalpapppa; ABarapappa; PVR; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; stavudine; and allantoin based on RNA-seq studies. WB:WBGene00022199 pfk-1.1 Predicted to enable several functions, including 6-phosphofructokinase activity; carbohydrate derivative binding activity; and identical protein binding activity. Predicted to be involved in canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and fructose 6-phosphate metabolic process. Predicted to be located in cytoplasm. Predicted to be part of 6-phosphofructokinase complex. Expressed in germ line; hypodermis; neurons; and pharynx. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Is an ortholog of human PFKL (phosphofructokinase, liver type) and PFKM (phosphofructokinase, muscle). WB:WBGene00022200 fard-1 Predicted to enable alcohol-forming very long-chain fatty acyl-CoA reductase activity. Predicted to be involved in long-chain fatty-acyl-CoA metabolic process. Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctate type 4. Is an ortholog of human FAR1 (fatty acyl-CoA reductase 1). WB:WBGene00022201 Y71H10B.1 Predicted to enable 5'-nucleotidase activity. Expressed in tail. Used to study obesity. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Is an ortholog of human NT5C2 (5'-nucleotidase, cytosolic II). WB:WBGene00022202 Y72A10A.1 Enriched in muscle cell; neurons; rectal muscle; and retrovesicular ganglion based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily and F-box-like domain superfamily. WB:WBGene00022203 Y73B3A.1 Predicted to be located in nucleus. WB:WBGene00022204 Y73B3A.2 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq studies. WB:WBGene00022205 Y73B3A.3 Enriched in cephalic sheath cell; germline precursor cell; and interneuron based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by mianserin and bisphenol A based on RNA-seq studies. WB:WBGene00022206 Y73B3A.4 Enriched in RIM; body wall muscle cell; and interneuron based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Six-bladed beta-propeller, TolB-like. WB:WBGene00022207 elk-2 Enriched in OLL; PVD; and head mesodermal cell based on microarray and RNA-seq studies. Is affected by several genes including daf-16; clk-1; and pgl-1 based on microarray and RNA-seq studies. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Lewy body dementia; and schizophrenia. Human ELK1 enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear receptor coactivator activity. Is an ortholog of human ELK1 (ETS transcription factor ELK1). WB:WBGene00022208 Y73B3A.6 No description available WB:WBGene00022209 Y73B3A.7 Enriched in I5 neuron; arcade cell; cholinergic neurons; pharyngeal-intestinal valve cell; and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022210 Y73B3A.8 Enriched in germline precursor cell based on tiling array studies. Is affected by several genes including ain-1; ain-2; and set-6 based on tiling array; RNA-seq; and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00022211 Y73B3A.9 Enriched in AVK; OLL; PVD; germ line; and germline precursor cell based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including rotenone; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00022213 Y73B3A.11 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by silicon dioxide nanoparticle based on RNA-seq studies. WB:WBGene00022214 cal-6 Enriched in head mesodermal cell and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; eat-2; and alg-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00022215 Y73B3A.13 Enriched in F cell and U cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022216 fbxa-16 Enriched in ABalpppppp; ABpraaappp; NSM; rectal gland cell; and tail precursor cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including tryptophan; methylmercuric chloride; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00022217 fbxa-221 Enriched in AVA; AVE; dopaminergic neurons; and neurons based on tiling array and microarray studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022218 Y73B3A.16 Enriched in germline precursor cell; head mesodermal cell; and pm6 based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-10; sek-1; and fbf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by four chemicals including Diazinon; paraquat; and Colistin based on microarray studies. WB:WBGene00022219 Y73B3A.18 Enriched in PVR; germ line; sensory neurons; and somatic gonad precursor based on proteomic; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including Tunicamycin; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00022220 Y73B3A.19 No description available WB:WBGene00022221 Y73B3A.20 Enriched in NSM; OLL; PVD; germ line; and intestine based on microarray and RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022222 Y73B3A.21 Is affected by several genes including hsf-1; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022223 Y73B3B.1 Enriched in neurons based on tiling array studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545); CH domain superfamily; Calponin homology domain; Calponin homology (CH) domain; and SPK domain. WB:WBGene00022224 set-28 Expressed in germ line. Is predicted to encode a protein with the following domains: SET domain superfamily and SET domain. WB:WBGene00022225 Y73B3B.3 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00022227 Y73B3B.5 Enriched in germ line; head mesodermal cell; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00022228 Y73B6A.1 Predicted to enable histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. Predicted to be part of nucleosome. WB:WBGene00022229 Y73B6A.2 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pmk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00022230 Y73B6A.3 Enriched in head mesodermal cell and interfacial epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022231 tyr-6 Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in oculocutaneous albinism type III and pigmentation disease. Is an ortholog of human DCT (dopachrome tautomerase). WB:WBGene00022232 exos-2 Predicted to enable RNA binding activity. Predicted to be involved in RNA metabolic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in short stature, hearing loss, retinitis pigmentosa, and distinctive facies. Is an ortholog of human EXOSC2 (exosome component 2). WB:WBGene00022233 ipla-6 Predicted to enable calcium-independent phospholipase A2 activity. Predicted to be involved in arachidonic acid metabolic process. Predicted to be located in membrane. Is an ortholog of human PNPLA8 (patatin like phospholipase domain containing 8). WB:WBGene00022235 sqd-1 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of catalytic step 2 spliceosome. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 3 and hepatocellular carcinoma. Is an ortholog of human HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B) and HNRNPDL (heterogeneous nuclear ribonucleoprotein D like). WB:WBGene00022236 Y73B6BL.12 Enriched in AFD; GABAergic neurons; and germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Thioredoxin domain; Thioredoxin; and Thioredoxin-like superfamily. WB:WBGene00022237 Y73B6BL.14 Predicted to enable ATP binding activity; DNA binding activity; and DNA ligase (ATP) activity. Predicted to be involved in DNA recombination; DNA repair; and DNA replication. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 20 and pancreatic cancer. Is an ortholog of human LIG3 (DNA ligase 3). WB:WBGene00022239 Y73B6BL.16 No description available WB:WBGene00022240 shl-1 Predicted to enable A-type (transient outward) potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in dendrite and membrane. Predicted to be part of voltage-gated potassium channel complex. Expressed in body wall musculature; muscle cell; neurons; pharynx; and tail. Human ortholog(s) of this gene implicated in Brugada syndrome 9 and spinocerebellar ataxia type 19/22. Is an ortholog of human KCND2 (potassium voltage-gated channel subfamily D member 2) and KCND3 (potassium voltage-gated channel subfamily D member 3). WB:WBGene00022242 sfrp-1 Predicted to enable Wnt-protein binding activity. Predicted to be involved in canonical Wnt signaling pathway and non-canonical Wnt signaling pathway. Located in nucleus. Expressed in head muscle and ventral cord neurons. Human ortholog(s) of this gene implicated in in situ carcinoma; leiomyoma; and renal cell carcinoma. Is an ortholog of human SFRP1 (secreted frizzled related protein 1). WB:WBGene00022243 Y73B6BL.22 Predicted to be located in membrane. WB:WBGene00022244 Y73B6BL.23 Enriched in BAG; RID; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and elt-2 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00022245 acp-6 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00022246 acp-7 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00022247 lgc-10 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00022248 Y73B6BL.27 Enriched in germ line; hypodermis; muscle cell; neurons; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; proteomic; and RNA-seq studies. Is affected by four chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022249 Y73B6BL.28 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; unc-30; and hpl-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00022250 Y73B6BL.29 Predicted to enable pseudouridine synthase activity. Predicted to be involved in tRNA pseudouridine synthesis. Is an ortholog of human PUSL1 (pseudouridine synthase like 1). WB:WBGene00022251 blos-2 Predicted to enable gamma-tubulin binding activity. Involved in endosomal transport. Predicted to be part of BLOC-1 complex; BORC complex; and gamma-tubulin complex. Expressed in head. Is an ortholog of human BLOC1S2 (biogenesis of lysosomal organelles complex 1 subunit 2). WB:WBGene00022252 Y73B6BL.31 Predicted to be located in membrane. Is an ortholog of human SLC35F3 (solute carrier family 35 member F3) and SLC35F4 (solute carrier family 35 member F4). WB:WBGene00022253 hrpf-2 Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleoplasm. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in Sjogren's syndrome; hepatocellular carcinoma; and syndromic X-linked intellectual disability. Is an ortholog of human GRSF1 (G-rich RNA sequence binding factor 1) and HNRNPF (heterogeneous nuclear ribonucleoprotein F). WB:WBGene00022254 nlp-71 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00022255 tmed-13 Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in intracellular membrane-bounded organelle. WB:WBGene00022256 Y73B6BL.37 Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Is an ortholog of human PLB1 (phospholipase B1). WB:WBGene00022257 puf-11 Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in post-transcriptional regulation of gene expression. Predicted to be located in cytoplasm and nucleus. WB:WBGene00022258 Y73C8B.1 Predicted to enable hydrolase activity. WB:WBGene00022259 Y73C8B.2 Predicted to enable hydrolase activity. WB:WBGene00022260 Y73C8B.3 Predicted to enable hydrolase activity. WB:WBGene00022261 clec-210 Enriched in intestine based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-six chemicals including hydrogen sulfide; tryptophan; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00022262 Y73C8C.3 Predicted to be involved in innate immune response. WB:WBGene00022263 Y73C8C.4 Enriched in amphid sheath cell and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including aldicarb; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00022264 sdz-34 Is affected by rsr-2; adr-1; and camt-1 based on tiling array and RNA-seq studies. WB:WBGene00022265 Y73C8C.8 Predicted to enable metal ion binding activity. Predicted to be involved in innate immune response. WB:WBGene00022266 srt-56 Predicted to be located in membrane. WB:WBGene00022267 Y73C8C.10 Predicted to enable FMN binding activity and oxidoreductase activity. WB:WBGene00022268 Y73E7A.1 Predicted to enable transcription coactivator activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human CCDC124 (coiled-coil domain containing 124). WB:WBGene00022269 aatf-1 Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleolus. Is an ortholog of human AATF (apoptosis antagonizing transcription factor). WB:WBGene00022270 Y73E7A.3 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC35F2 (solute carrier family 35 member F2). WB:WBGene00022271 cpx-1 Predicted to enable SNARE binding activity. Predicted to be involved in regulation of neurotransmitter secretion and synaptic vesicle exocytosis. Located in axon and synapse. Expressed in head neurons; motor neurons; nervous system; tail neurons; and ventral cord neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 63. Is an ortholog of human CPLX1 (complexin 1) and CPLX2 (complexin 2). WB:WBGene00022272 Y73E7A.5 Is affected by several genes including eat-2; clk-1; and set-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Sodium Chloride; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00022273 Y73E7A.6 Predicted to be located in membrane. Is an ortholog of human BLCAP (BLCAP apoptosis inducing factor). WB:WBGene00022274 Y73E7A.8 Enriched in hypodermis and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including aldicarb; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00022275 txt-7 Is affected by several genes including daf-2; eat-2; and elt-2 based on tiling array and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022276 nlp-40 Predicted to enable neuropeptide receptor binding activity. Involved in neuropeptide signaling pathway and positive regulation of defecation. Located in extracellular space. Expressed in coelomocyte and intestinal cell. WB:WBGene00022277 homt-1 Predicted to enable N-terminal protein N-methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in cytoplasm. Expressed in PVT and uterus. Is an ortholog of human NTMT1 (N-terminal Xaa-Pro-Lys N-methyltransferase 1). WB:WBGene00022278 rcor-1 Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of histone deacetylase complex and transcription regulator complex. Is an ortholog of human RCOR1 (REST corepressor 1); RCOR2 (REST corepressor 2); and RCOR3 (REST corepressor 3). WB:WBGene00022279 sesn-1 Predicted to enable leucine binding activity and oxidoreductase activity, acting on peroxide as acceptor. Predicted to be involved in several processes, including cellular response to leucine; cellular response to leucine starvation; and negative regulation of TORC1 signaling. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SESN1 (sestrin 1). WB:WBGene00022280 Y74C10AL.2 Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway. Predicted to be located in membrane. Is an ortholog of human TMEM50A (transmembrane protein 50A) and TMEM50B (transmembrane protein 50B). WB:WBGene00022281 abtm-1 Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in intracellular iron ion homeostasis. Located in mitochondrion. Expressed in coelomocyte; hypodermis; intestine; and spermatheca. Used to study X-linked sideroblastic anemia with ataxia. Human ortholog(s) of this gene implicated in X-linked sideroblastic anemia with ataxia. Is an ortholog of human ABCB7 (ATP binding cassette subfamily B member 7). WB:WBGene00022282 Y74C10AR.2 Enriched in arcade cell; male-specific anatomical entity; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00022283 lgc-27 Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in AIYL and AIYR. WB:WBGene00022284 glb-33 Predicted to enable heme binding activity and oxygen binding activity. Predicted to be located in membrane. Expressed in neurons and somatic nervous system. WB:WBGene00022285 Y75B7AL.2 Predicted to be involved in protein localization and receptor-mediated endocytosis. Predicted to be located in apical plasma membrane and endocytic vesicle. Human ortholog(s) of this gene implicated in megaloblastic anemia. Is an ortholog of human AMN (amnion associated transmembrane protein). WB:WBGene00022286 rga-4 Enables GTPase activator activity. Involved in asymmetric protein localization involved in cell fate determination; cortical actin cytoskeleton organization; and regulation of actin filament-based process. Expressed in embryonic cell and germ line. Is an ortholog of human ARHGAP11A (Rho GTPase activating protein 11A). WB:WBGene00022287 Y75B7AR.1 Enriched in several structures, including arcade cell; head mesodermal cell; muscle cell; neurons; and somatic nervous system based on Chronogram; microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including 1-methylnicotinamide; nicotinic acid; and Mercuric Chloride based on RNA-seq and microarray studies. WB:WBGene00022288 Y75B7B.1 Predicted to be part of DNA-directed RNA polymerase complex. WB:WBGene00022289 Y75B7B.2 Predicted to enable transcription cis-regulatory region binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00022290 Y75D11A.1 Is affected by several genes including pqm-1; ash-2; and adr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fluoranthene and Sirolimus based on microarray studies. WB:WBGene00022291 Y75D11A.2 Enriched in muscle cell based on microarray studies. Is affected by several genes including dpy-10; sir-2.1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including paraquat; Colistin; and Sirolimus based on microarray studies. WB:WBGene00022292 Y75D11A.3 Enriched in MSpaapaa; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; 4-bromodiphenyl ether; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00022293 Y75D11A.4 No description available WB:WBGene00022294 Y75D11A.5 No description available WB:WBGene00022295 cng-2 Predicted to enable cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Located in neuronal cell body. Expressed in amphid neurons. Human ortholog(s) of this gene implicated in achromatopsia 2 and retinitis pigmentosa 49. Is an ortholog of several human genes including CNGA1 (cyclic nucleotide gated channel subunit alpha 1); CNGA2 (cyclic nucleotide gated channel subunit alpha 2); and CNGA3 (cyclic nucleotide gated channel subunit alpha 3). WB:WBGene00022296 xpc-1 Predicted to enable damaged DNA binding activity and single-stranded DNA binding activity. Involved in response to UV. Predicted to be located in cytoplasm. Predicted to be part of XPC complex and nucleotide-excision repair factor 2 complex. Used to study xeroderma pigmentosum. Human ortholog(s) of this gene implicated in pancreatic cancer; serous cystadenocarcinoma; and xeroderma pigmentosum group C. Is an ortholog of human XPC (XPC complex subunit, DNA damage recognition and repair factor). WB:WBGene00022297 Y76B12C.3 Predicted to enable oxidoreductase activity. Predicted to be located in endoplasmic reticulum lumen. Expressed in g1AL; g1AR; g1P; g2L; and g2R. Is an ortholog of human SELENOF (selenoprotein F). WB:WBGene00022298 Y76B12C.4 Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. WB:WBGene00022299 Y76B12C.5 No description available WB:WBGene00022300 Y76B12C.6 Enriched in arcade cell; germ line; germline precursor cell; and pharyngeal-intestinal valve cell based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and sir-2.1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00022301 cpsf-1 Predicted to enable RNA binding activity. Predicted to be involved in mRNA polyadenylation. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Human ortholog(s) of this gene implicated in myopia. Is an ortholog of human CPSF1 (cleavage and polyadenylation specific factor 1). WB:WBGene00022302 Y76B12C.8 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00022303 Y76B12C.9 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Atrazine based on microarray studies. WB:WBGene00022304 Y76G2A.1 No description available WB:WBGene00022305 Y76G2A.2 No description available WB:WBGene00022306 hxk-3 Predicted to enable fructokinase activity and glucokinase activity. Predicted to be involved in carbohydrate metabolic process; glucose 6-phosphate metabolic process; and intracellular glucose homeostasis. Predicted to be located in cytosol and mitochondrion. WB:WBGene00022307 nadk-1 Predicted to enable NAD+ kinase activity. Predicted to be involved in NAD metabolic process. Predicted to be located in mitochondrion. Is an ortholog of human NADK2 (NAD kinase 2, mitochondrial). WB:WBGene00022308 Y77E11A.3 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00022309 rpc-11 Predicted to enable DNA-directed 5'-3' RNA polymerase activity; nucleic acid binding activity; and zinc ion binding activity. Predicted to contribute to RNA polymerase III activity. Predicted to be involved in termination of RNA polymerase III transcription. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 21. Is an ortholog of human POLR3K (RNA polymerase III subunit K). WB:WBGene00022310 Y77E11A.7 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by seven chemicals including hydrogen sulfide; Zidovudine; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022311 Y77E11A.8 Enriched in NSM and excretory cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and pmk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00022312 clec-171 Enriched in NSM and Y cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00022313 Y77E11A.12 Predicted to be involved in negative regulation of toll-like receptor 9 signaling pathway. Predicted to be located in membrane. Expressed in body wall musculature. Is an ortholog of human GRAMD4 (GRAM domain containing 4). WB:WBGene00022314 spp-31 Enriched in several structures, including amphid sensillum; dopaminergic neurons; intestine; mechanosensory neurons; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including rotenone; Tunicamycin; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Saposin-like. WB:WBGene00022315 Y81B9A.1 Is affected by several genes including pgl-1; glh-1; and hda-1 based on RNA-seq studies. Is affected by copper sulfate and adsorbable organic bromine compound based on microarray studies. WB:WBGene00022316 Y81B9A.2 Enriched in Z1.p; Z4.a; male distal tip cell; male-specific anatomical entity; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00022317 Y81B9A.3 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022318 Y82E9BL.1 Predicted to be located in membrane. WB:WBGene00022319 Y82E9BL.2 Enriched in several structures, including ABarpapaapp; MSpppaaa; NSM; SMB; and head mesodermal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00022320 Y82E9BL.3 Predicted to be located in membrane. WB:WBGene00022321 fbxa-25 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on microarray and RNA-seq studies. Is affected by cadmium and Atrazine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box A protein FB224; F-box-like domain superfamily; and F-box domain. WB:WBGene00022322 Y82E9BL.5 Predicted to be located in membrane. WB:WBGene00022323 Y82E9BL.6 Predicted to be located in membrane. WB:WBGene00022324 fbxa-26 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including methylmercury hydroxide; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022325 fbxa-5 Enriched in excretory cell; intestine; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022326 fbxa-14 Enriched in ABprpapppa; intestine; mechanosensory neurons; and rectal gland cell based on microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twenty-one chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022327 fbxa-15 Enriched in intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including D-glucose; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022328 Y82E9BL.12 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00022329 fbxa-79 Enriched in AFD; ASER; intestine; muscle cell; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; D-glucopyranose; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00022330 fbxa-80 Enriched in body wall muscle cell; coelomocyte; intestine; neurons; and rectal epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and npr-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Tunicamycin; levamisole; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00022331 fbxa-19 Enriched in AVA; GABAergic neurons; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including skn-1; hsf-1; and npr-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including R24; paraquat; and bortezomib based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022332 fbxa-20 Enriched in AVE; GABAergic neurons; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Colistin based on microarray studies. WB:WBGene00022333 fbxa-27 Enriched in ABalpppapa; ABpraaaapa; amphid neurons; excretory cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including hydrogen sulfide; methylmercury hydroxide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00022334 Y82E9BR.1 Enriched in several structures, including ABalaapppa; PLM; amphid neurons; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on proteomic; microarray; and RNA-seq studies. Is affected by fourteen chemicals including 1-methylnicotinamide; methylmercuric chloride; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00022335 Y82E9BR.2 Enriched in germ line; germline precursor cell; and hypodermis based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00022336 Y82E9BR.3 Predicted to enable lipid binding activity and proton transmembrane transporter activity. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in mitochondrial membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Expressed in hypodermis and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma; early-onset dystonia and/or spastic paraplegia; and urinary bladder cancer. Is an ortholog of human ATP5MC1 (ATP synthase membrane subunit c locus 1). WB:WBGene00022337 pals-16 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; age-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including Alovudine; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00022338 Y82E9BR.5 Enriched in OLL; PVD; and intestine based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and pmk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Tunicamycin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00022339 Y82E9BR.6 Enriched in GABAergic neurons; body wall muscle cell from C lineage; and body wall muscle cell from MS lineage based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022340 Y82E9BR.7 Enriched in male based on RNA-seq studies. Is affected by lin-15B and daf-2 based on microarray studies. WB:WBGene00022341 Y82E9BR.8 Is affected by spn-4 and set-2 based on RNA-seq studies. WB:WBGene00022342 Y82E9BR.9 Enriched in DA neuron; PLML; PLMR; and VA neuron based on tiling array and single-cell RNA-seq studies. Is affected by rsr-2 based on tiling array studies. WB:WBGene00022343 Y82E9BR.10 Enriched in head mesodermal cell and hypodermis based on RNA-seq studies. Is affected by several genes including clk-1; cyc-1; and mir-34 based on microarray and RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and Atrazine based on RNA-seq and microarray studies. WB:WBGene00022344 pals-40 Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00022345 fbxa-138 Predicted to be located in membrane. WB:WBGene00022346 pals-17 Enriched in ABplppppap; ABprppppap; head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and let-60 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; stavudine; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00022347 Y82E9BR.14 Predicted to enable ceramide 1-phosphate binding activity and ceramide 1-phosphate transfer activity. Predicted to be involved in ceramide transport and intermembrane lipid transfer. Predicted to be located in cytosol. Is an ortholog of human GLTP (glycolipid transfer protein). WB:WBGene00022348 lelo-2 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in germ line. Human ortholog(s) of this gene implicated in acute kidney failure. Is an ortholog of human SLC22A2 (solute carrier family 22 member 2). WB:WBGene00022349 Y82E9BR.17 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalaapppa; male distal tip cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by twenty chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. WB:WBGene00022350 Y82E9BR.18 Predicted to enable ribosomal large subunit binding activity and tRNA binding activity. Predicted to be involved in rescue of stalled ribosome and ribosome-associated ubiquitin-dependent protein catabolic process. Predicted to be part of RQC complex. Is an ortholog of human NEMF (nuclear export mediator factor). WB:WBGene00022351 Y82E9BR.19 Enriched in several structures, including MSaapaapa; MSpapaapa; RID; germ line; and germline precursor cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including rotenone; Alovudine; and stavudine based on RNA-seq studies. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00022352 Y82E9BR.20 Enriched in NSM; head mesodermal cell; muscle cell; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00022353 pals-18 Enriched in OLL; PVD; head mesodermal cell; intestine; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including rotenone; Cry5B; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00022354 Y82E9BR.22 Enriched in AFD and germ line based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and clk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; mianserin; and stavudine based on RNA-seq and microarray studies. WB:WBGene00022356 eak-3 Expressed in XXXL and XXXR. WB:WBGene00022357 kbp-4 Located in kinetochore. Part of Ndc80 complex. WB:WBGene00022358 Y92H12A.2 Predicted to enable sodium channel inhibitor activity and ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and regulation of dendrite morphogenesis. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Is an ortholog of human NEDD4 (NEDD4 E3 ubiquitin protein ligase) and NEDD4L (NEDD4 like E3 ubiquitin protein ligase). WB:WBGene00022360 ints-3 Predicted to be located in cytoplasm. Is an ortholog of human INTS3 (integrator complex subunit 3). WB:WBGene00022361 Y92H12A.5 Predicted to be involved in tRNA methylation. Is an ortholog of human THADA (THADA armadillo repeat containing). WB:WBGene00022363 Y92H12BL.1 Predicted to enable N6-threonylcarbomyladenosine methylthiotransferase activity. Predicted to be involved in tRNA methylthiolation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in gestational diabetes and type 2 diabetes mellitus. Is an ortholog of human CDKAL1 (CDK5 regulatory subunit associated protein 1 like 1). WB:WBGene00022365 Y92H12BL.4 Predicted to enable 4 iron, 4 sulfur cluster binding activity; metal ion binding activity; and methylthiotransferase activity. WB:WBGene00022366 Y92H12BL.5 Predicted to enable pyrophosphatase activity. Predicted to be involved in diphosphoinositol polyphosphate metabolic process and nucleotide catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of several human genes including NUDT10 (nudix hydrolase 10); NUDT3 (nudix hydrolase 3); and NUDT4 (nudix hydrolase 4). WB:WBGene00022367 Y92H12BM.1 Enriched in ABplpppaaa; ABprpppaaa; AVJ; head mesodermal cell; and motor neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and lin-28 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: WW domain superfamily; WW domain; and Phosphorylation site. Is an ortholog of human ARHGAP39 (Rho GTPase activating protein 39). WB:WBGene00022368 Y92H12BR.2 Enriched in germ line; intestine; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; npr-1; and pgl-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by six chemicals including paraquat; Atrazine; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022369 Y92H12BR.3 Predicted to be located in membrane. WB:WBGene00022370 Y92H12BR.4 Is affected by several genes including daf-2; clk-1; and tph-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00022371 set-29 Predicted to enable histone H3K36 methyltransferase activity; histone H3K4 methyltransferase activity; and transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Expressed in intestine and muscle cell. Is an ortholog of human SETD4 (SET domain containing 4). WB:WBGene00022372 Y92H12BR.7 Predicted to be located in cytoplasm. Is an ortholog of human PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like). WB:WBGene00022373 mrpl-15 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL15 (mitochondrial ribosomal protein L15). WB:WBGene00022374 nhr-277 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in hormone-mediated signaling pathway; regulation of transcription by RNA polymerase II; and tissue development. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. WB:WBGene00022375 Y94H6A.2 Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Tunicamycin; 4-bromodiphenyl ether; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF684) and Protein of unknown function DUF684. WB:WBGene00022376 Y94H6A.3 Enriched in several structures, including ABalaapppa; ABalapaaaa; PVD; ciliated neurons; and germ line based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including rotenone; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00022377 gpx-4 Predicted to enable glutathione peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including diabetes mellitus (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human GPX3 (glutathione peroxidase 3) and GPX5 (glutathione peroxidase 5). WB:WBGene00022378 Y94H6A.5 Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Is an ortholog of human DDX54 (DEAD-box helicase 54). WB:WBGene00022379 Y94H6A.7 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; conduct disorder; and diabetes mellitus (multiple). Is an ortholog of human ACP1 (acid phosphatase 1). WB:WBGene00022380 ndua-12 Predicted to be involved in response to oxidative stress. Located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 23. Is an ortholog of human NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12). WB:WBGene00022381 ubxn-2 Enables K48-linked polyubiquitin modification-dependent protein binding activity and protein kinase binding activity. Involved in several processes, including developmental process involved in reproduction; establishment of mitotic spindle orientation; and negative regulation of protein localization to centrosome. Located in nucleus; perinuclear region of cytoplasm; and spindle pole centrosome. Expressed in several structures, including gonad and spermatocyte. Is an ortholog of human NSFL1C (NSFL1 cofactor). WB:WBGene00022382 Y94H6A.10 Predicted to enable peptidase activity. Predicted to be involved in proteolysis. WB:WBGene00022384 Y95B8A.3 No description available WB:WBGene00022385 Y95B8A.4 Predicted to be located in membrane. WB:WBGene00022386 Y95B8A.6 Enriched in RICL; RICR; hypodermis; muscle cell; and neurons based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including rotenone; Tunicamycin; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cystine-knot cytokine. WB:WBGene00022388 zfr-1 Predicted to enable double-stranded RNA binding activity and single-stranded RNA binding activity. Acts upstream of or within with a positive effect on axon guidance. Predicted to be part of spliceosomal complex. Is an ortholog of human ZFR (zinc finger RNA binding protein) and ZFR2 (zinc finger RNA binding protein 2). WB:WBGene00022389 pde-6 Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity. Involved in negative regulation of oocyte maturation. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease. Is an ortholog of human PDE8A (phosphodiesterase 8A) and PDE8B (phosphodiesterase 8B). WB:WBGene00022390 him-19 Involved in meiotic DNA double-strand break formation and regulation of synaptonemal complex assembly. WB:WBGene00022391 prhg-1 Predicted to enable guanyl-nucleotide exchange factor activity. Is an ortholog of human PLEKHG7 (pleckstrin homology and RhoGEF domain containing G7). WB:WBGene00022392 Y97E10AL.1 Predicted to be involved in proprioception; sensory perception of mechanical stimulus; and taxis. Predicted to be located in sensory dendrite. Is an ortholog of human STUM (stum, mechanosensory transduction mediator homolog). WB:WBGene00022393 abhd-12 Predicted to enable acylglycerol lipase activity and lysophospholipase activity. Predicted to be involved in monoacylglycerol catabolic process and phosphatidylserine catabolic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in PHARC syndrome. Is an ortholog of human ABHD12B (abhydrolase domain containing 12B). WB:WBGene00022394 natb-1 Predicted to enable peptide alpha-N-acetyltransferase activity. Predicted to be part of NatB complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 73. Is an ortholog of human NAA20 (N-alpha-acetyltransferase 20, NatB catalytic subunit). WB:WBGene00022395 ceh-76 Predicted to enable DNA binding activity. Predicted to be located in nucleus. WB:WBGene00022396 Y97E10AR.1 Enriched in g1; head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; methylmercuric chloride; and sesamin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00022397 Y97E10AR.2 Predicted to enable glutathione hydrolase activity. Predicted to be involved in glutathione catabolic process. Predicted to be located in plasma membrane. Expressed in body wall musculature; head neurons; and intestine. WB:WBGene00022398 Y97E10AR.3 Enriched in BAG; germ line; intestine; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-12; sir-2.1; and npr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00022399 Y97E10AR.4 Enriched in ABplpppppp; ABprpppppp; M cell; enteric muscle; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00022400 rpb-9 Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II; transcription initiation at RNA polymerase II promoter; and transcription-coupled nucleotide-excision repair. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase II, core complex. Is an ortholog of human POLR2I (RNA polymerase II subunit I). WB:WBGene00022401 Y97E10AR.6 Predicted to be located in cytoplasm. Is an ortholog of human BSDC1 (BSD domain containing 1). WB:WBGene00022402 lmtr-2 Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in several processes, including cellular response to amino acid stimulus; positive regulation of TOR signaling; and regulation of cell growth. Predicted to be part of Ragulator complex. Is an ortholog of human LAMTOR2 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 2). WB:WBGene00022403 Y97E10B.1 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00022404 srsx-5 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in ASIL; ASIR; ASKL; ASKR; and AWC-OFF. WB:WBGene00022405 srsx-6 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Expressed in head neurons. WB:WBGene00022406 srsx-7 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00022407 srsx-4 Enriched in AWC-OFF based on single-cell RNA-seq studies. Is affected by lin-15B; adr-1; and etr-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00022408 srsx-3 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in non-motile cilium. Expressed in AWBL; AWBR; AWC-OFF; AWCL; and AWCR. WB:WBGene00022409 srt-53 Predicted to be located in membrane. WB:WBGene00022410 Y97E10C.1 Enriched in several structures, including anal sphincter muscle; body wall musculature; head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including rotenone; D-glucose; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00022411 Y102A11A.1 Predicted to be located in membrane. WB:WBGene00022412 Y102A11A.2 Expressed in head and tail. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022413 Y102A11A.3 Enriched in coelomocyte; head mesodermal cell; intestine; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00022414 Y102A11A.4 No description available WB:WBGene00022415 Y102A11A.5 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and ABarpppapa based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-two chemicals including aldicarb; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00022416 ergi-1 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum; and membrane. Human ortholog(s) of this gene implicated in neurogenic-type arthrogryposis multiplex congenita-2. Is an ortholog of human ERGIC1 (endoplasmic reticulum-golgi intermediate compartment 1). WB:WBGene00022417 smex-2 Predicted to be located in membrane. WB:WBGene00022418 igcm-4 Predicted to be located in membrane. Is an ortholog of human FGFRL1 (fibroblast growth factor receptor like 1). WB:WBGene00022419 Y102A11A.9 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppppapa; excretory gland cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and sek-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; D-glucopyranose; and Cadmium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022420 wdr-4 Predicted to be involved in tRNA modification. Predicted to be located in cytosol and nucleus. Predicted to be part of tRNA methyltransferase complex. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome and microcephaly, growth deficiency, seizures, and brain malformations. Is an ortholog of human WDR4 (WD repeat domain 4). WB:WBGene00022421 Y102E9.3 Enriched in NSM; anal sphincter muscle; and coelomocyte based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00022423 nhr-41 Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including excretory cell; hypodermis; neurons; rectum; and vulva. Is an ortholog of human NR2C1 (nuclear receptor subfamily 2 group C member 1) and NR2C2 (nuclear receptor subfamily 2 group C member 2). WB:WBGene00022425 plst-1 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Expressed in hypodermis; intestine; and pharynx. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 76 and osteoporosis. Is an ortholog of human LCP1 (lymphocyte cytosolic protein 1); PLS1 (plastin 1); and PLS3 (plastin 3). WB:WBGene00022426 Y104H12D.2 Enriched in several structures, including ABalapaaaa; ABalappapa; MSaapapa; germ line; and mechanosensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and sir-2.1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by six chemicals including stavudine; Zidovudine; and antimycin based on RNA-seq and microarray studies. WB:WBGene00022427 spl-3 Predicted to enable sphinganine-1-phosphate aldolase activity. Predicted to be involved in sphingolipid catabolic process. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in nephrotic syndrome type 14. Is an ortholog of human SGPL1 (sphingosine-1-phosphate lyase 1). WB:WBGene00022428 rmif-2 Predicted to enable DNA binding activity. Involved in several processes, including chiasma assembly; positive regulation of brood size; and positive regulation of cell cycle process. Located in nucleus. WB:WBGene00022429 Y108F1.1 Is affected by several genes including daf-16; sek-1; and isp-1 based on RNA-seq and microarray studies. Is affected by cadmium; Sirolimus; and allantoin based on microarray studies. WB:WBGene00022430 Y108F1.2 No description available WB:WBGene00022431 set-33 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022432 math-43 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; sek-1; and cat-2 based on microarray and RNA-seq studies. Is affected by four chemicals including mianserin; Alovudine; and Cisplatin based on RNA-seq studies. WB:WBGene00022433 Y108F1.5 Predicted to enable helicase activity. Is an ortholog of human DHX35 (DEAH-box helicase 35). WB:WBGene00022434 Y108G3AL.2 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of precatalytic spliceosome. Is an ortholog of human PRPF38B (pre-mRNA processing factor 38B). WB:WBGene00022435 cfap-36 Located in axoneme and ciliary base. Expressed in ciliated neurons. Is an ortholog of human CFAP36 (cilia and flagella associated protein 36). WB:WBGene00022438 Y110A2AL.1 Is affected by several genes including daf-2; pie-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Smr domain and Smr domain superfamily. WB:WBGene00022439 Y110A2AL.2 Expressed in g2L and g2R. Is predicted to encode a protein with the following domain: CC domain. WB:WBGene00022440 Y110A2AL.3 Enriched in OLL and PVD based on tiling array studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including hydrogen sulfide; 1-methylnicotinamide; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CC domain. WB:WBGene00022441 Y110A2AL.4 Enriched in several structures, including ABarpaapap; accessory cell; anterior hypodermis; head neurons; and nerve ring neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-six chemicals including 1-methylnicotinamide; methylmercuric chloride; and sesamin based on RNA-seq and microarray studies. WB:WBGene00022442 Y110A2AL.5 Enriched in NSM based on tiling array studies. Is affected by several genes including clk-1; drh-3; and smg-2 based on tiling array; microarray; and RNA-seq studies. Is affected by fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; and PAN-3 domain. WB:WBGene00022443 Y110A2AL.6 Enriched in body wall muscle cell; male-specific anatomical entity; and in male based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including rrf-3; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including sodium arsenite; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00022444 Y110A2AL.7 Enriched in XXXL; XXXR; germ line; male-specific anatomical entity; and in male based on proteomic; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies. WB:WBGene00022445 Y110A2AL.9 Enriched in arcade cell and pharyngeal-intestinal valve cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including hydrogen sulfide; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CC domain. WB:WBGene00022446 Y110A2AL.10 Enriched in FLP based on microarray studies. Is affected by several genes including mex-3; mex-1; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube; Tunicamycin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Smr domain superfamily. WB:WBGene00022447 pigw-1 Predicted to enable glucosaminyl-phosphatidylinositol O-acyltransferase activity. Predicted to be involved in protein localization to plasma membrane. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 5. Is an ortholog of human PIGW (phosphatidylinositol glycan anchor biosynthesis class W). WB:WBGene00022448 pinn-1 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in regulation of macromolecule metabolic process; regulation of nitrogen compound metabolic process; and regulation of primary metabolic process. Predicted to be located in cytosol and nucleus. Is an ortholog of human PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1). WB:WBGene00022450 ubc-26 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum and nucleus. Is an ortholog of human UBE2J2 (ubiquitin conjugating enzyme E2 J2). WB:WBGene00022452 Y110A2AR.1 Predicted to be located in membrane. WB:WBGene00022453 ncap-1 Predicted to be involved in vesicle-mediated transport. Predicted to be located in membrane. Predicted to be part of clathrin vesicle coat. Expressed in nerve ring. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 21. Is an ortholog of human NECAP1 (NECAP endocytosis associated 1) and NECAP2 (NECAP endocytosis associated 2). WB:WBGene00022454 trf-2 Predicted to enable ubiquitin protein ligase binding activity. Human ortholog(s) of this gene implicated in brain disease. Is an ortholog of human TRAF1 (TNF receptor associated factor 1); TRAF3 (TNF receptor associated factor 3); and TRAF5 (TNF receptor associated factor 5). WB:WBGene00022455 tyms-1 Enables thymidylate synthase activity. Involved in dTMP biosynthetic process. Predicted to be located in cytosol and mitochondrion. Expressed in body wall musculature; gonad; nerve ring; and terminal bulb. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and rheumatoid arthritis. Is an ortholog of human TYMS (thymidylate synthetase). WB:WBGene00022456 pfkb-1.1 Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to be located in cytosol. Is an ortholog of several human genes including PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1); PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2); and PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3). WB:WBGene00022457 Y110A7A.7 Predicted to be involved in lipid metabolic process. WB:WBGene00022458 prp-31 Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U4 snRNP; precatalytic spliceosome; and spliceosomal tri-snRNP complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa 11. Is an ortholog of human PRPF31 (pre-mRNA processing factor 31). WB:WBGene00022459 Y110A7A.9 Predicted to be located in cytoplasm. Expressed in head. Used to study high grade glioma. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder and hypogonadotropic hypogonadism 14 with or without anosmia. Is an ortholog of human WDR11 (WD repeat domain 11). WB:WBGene00022460 use-1 Predicted to enable SNAP receptor activity. Predicted to be involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in endoplasmic reticulum. Predicted to be part of SNARE complex. Is an ortholog of human USE1 (unconventional SNARE in the ER 1). WB:WBGene00022462 Y110A7A.15 Enriched in germ line; head mesodermal cell; and tail hypodermis based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and rrf-3 based on microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00022463 elpc-1 Predicted to enable tRNA binding activity. Involved in several processes, including gamete generation; gene expression; and olfactory learning. Located in cytoplasm; neuron projection; and neuronal cell body. Expressed in CAN; HSN; pharynx; sensory neurons; and vulva. Used to study Riley-Day syndrome. Human ortholog(s) of this gene implicated in several diseases, including Riley-Day syndrome; medulloblastoma; and scoliosis. Is an ortholog of human ELP1 (elongator acetyltransferase complex subunit 1). WB:WBGene00022465 ift-20 Predicted to be involved in centrosome localization; intraciliary transport; and protein localization to cilium. Located in dendrite; neuronal cell body; and non-motile cilium. Expressed in ciliated neurons; sensory neurons; and tail. Is an ortholog of human IFT20 (intraflagellar transport 20). WB:WBGene00022466 Y119C1A.1 Predicted to enable metal ion binding activity. WB:WBGene00022467 Y119C1B.1 Predicted to be located in membrane. WB:WBGene00022469 Y119C1B.3 Predicted to be located in membrane. Is an ortholog of human TMEM26 (transmembrane protein 26). WB:WBGene00022470 mrpl-19 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL19 (mitochondrial ribosomal protein L19). WB:WBGene00022471 rnf-145 Predicted to enable transferase activity and zinc ion binding activity. Located in cis-Golgi network and trans-Golgi network. Is an ortholog of human RNF145 (ring finger protein 145). WB:WBGene00022472 Y119C1B.6 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00022473 bet-1 Enables SUMO binding activity and lysine-acetylated histone binding activity. Involved in several processes, including multicellular organismal locomotion; muscle cell cellular homeostasis; and regulation of DNA-templated transcription. Located in chromosome; metaphase plate; and nucleus. Expressed in several structures, including hypodermal cell and seam cell. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); lymphoma (multiple); and male infertility (multiple). Is an ortholog of human BRD2 (bromodomain containing 2) and BRDT (bromodomain testis associated). WB:WBGene00022474 zig-9 Enriched in SMB; head mesodermal cell; intestine; and spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; proteomic; RNA-seq; and microarray studies. Is affected by nine chemicals including diallyl trisulfide; mianserin; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Immunoglobulin-like fold and Immunoglobulin-like domain superfamily. WB:WBGene00022475 Y119C1B.10 Enriched in AVA and neurons based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; D-glucose; and levamisole based on RNA-seq and microarray studies. WB:WBGene00022476 fbxa-75 Enriched in RIH; cephalic sheath cell; dopaminergic neurons; hyp1; and hyp2 based on tiling array and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; nanoparticle; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00022477 fbxa-28 Is affected by several genes including eat-2; set-2; and npr-8 based on tiling array and RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022478 fbxa-35 Enriched in PLM and muscle cell based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Sodium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022479 fbxa-36 Enriched in ADF; AVA; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by seven chemicals including methylmercuric chloride; Sodium Chloride; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022480 Y119D3A.5 No description available WB:WBGene00022481 srz-9 Predicted to be located in membrane. WB:WBGene00022482 fbxa-208 Is affected by several genes including daf-16; dpy-10; and dcr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including silicon dioxide nanoparticle; Cry5B; and Hydrolyzable Tannins based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00022483 srz-8 Is affected by several genes including pry-1; etr-1; and tatn-1 based on tiling array and RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00022484 fbxa-77 Enriched in intestine; rect_D; rect_VL; rect_VR; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00022485 fbxa-63 Enriched in intestine; sensory neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Psoralens; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022486 fbxa-61 Enriched in OLL; PVD; head mesodermal cell; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; stavudine; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022487 fbxa-21 Enriched in OLL; PVD; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including 1-methylnicotinamide; rotenone; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00022488 orc-3 Enriched in several structures, including ABalppappa; ciliated neurons; germ line; head mesodermal cell; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including stavudine; Zidovudine; and antimycin based on RNA-seq; proteomic; and microarray studies. WB:WBGene00022489 Y119D3B.12 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to be part of U1 snRNP and U2-type prespliceosome. Is an ortholog of human LUC7L3 (LUC7 like 3 pre-mRNA splicing factor). WB:WBGene00022490 nspg-8 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00022491 Y119D3B.14 Predicted to enable GTPase activity. Predicted to be involved in mitochondrial translation and ribosome disassembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 39. Is an ortholog of human GFM2 (GTP dependent ribosome recycling factor mitochondrial 2). WB:WBGene00022492 dss-1 Involved in several processes, including intestinal absorption; positive regulation of protein ubiquitination; and vulval development. Located in cytoplasm and nucleus. Expressed in head neurons. WB:WBGene00022493 mrpl-45 Predicted to be located in mitochondrion. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in atherosclerosis. Is an ortholog of human MRPL45 (mitochondrial ribosomal protein L45). WB:WBGene00022494 fbxa-91 Enriched in AFD; intestine; rect_D; rect_VL; and rect_VR based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; Rifampin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00022495 fbxa-78 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; methylmercury hydroxide; and sesamin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022496 fbxa-92 Enriched in MSpaaaaa and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including D-glucopyranose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022497 Y119D3B.21 Enriched in several structures, including head mesodermal cell; neurons; pharyngeal muscle cell; rectal gland cell; and retrovesicular ganglion based on SAGE; tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including 1-methylnicotinamide; Tunicamycin; and mianserin based on RNA-seq and microarray studies. WB:WBGene00022498 hsd-2 Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in steroid biosynthetic process. Predicted to be located in membrane. Expressed in intestine. Human ortholog(s) of this gene implicated in CHILD syndrome and CK syndrome. Is an ortholog of human SDR42E2 (short chain dehydrogenase/reductase family 42E, member 2). WB:WBGene00022499 set-30 Enables histone H3K4 methyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus. WB:WBGene00022500 lfi-1 Located in kinetochore microtubule and nucleus. Is an ortholog of human CROCC (ciliary rootlet coiled-coil, rootletin). WB:WBGene00022501 ZC8.6 Predicted to enable 1-phosphatidylinositol 4-kinase activity. Predicted to be involved in Golgi organization; endosome organization; and phosphatidylinositol phosphate biosynthetic process. Predicted to be located in endosome; plasma membrane; and trans-Golgi network. Is an ortholog of human PI4K2A (phosphatidylinositol 4-kinase type 2 alpha) and PI4K2B (phosphatidylinositol 4-kinase type 2 beta). WB:WBGene00022502 ZC13.1 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in positive regulation of ERAD pathway. Predicted to be located in membrane. Is an ortholog of human RNFT1 (ring finger protein, transmembrane 1) and RNFT2 (ring finger protein, transmembrane 2). WB:WBGene00022503 ZC13.2 Predicted to be located in membrane. WB:WBGene00022504 mam-1 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in regulation of T cell activation and regulation of T cell migration. Predicted to be located in membrane. WB:WBGene00022505 idpp-15 Enriched in several structures, including ABplppppaa; ABprppppaa; AUA; accessory cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; tiling array; and microarray studies. Is affected by nineteen chemicals including Ethanol; 1-methylnicotinamide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00022506 ZC21.6 Enriched in Cappppv; Cpppppv; coelomocyte; neurons; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; age-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00022507 ZC21.8 Enriched in ADEshL; ADEshR; NSM; intestine; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; multi-walled carbon nanotube; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Uncharacterized protein ZC21.8. WB:WBGene00022508 ZC53.1 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including bisphenol A; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00022509 ZC53.2 Is affected by rsr-2 and sir-2.1 based on tiling array and microarray studies. Is affected by Atrazine based on microarray studies. WB:WBGene00022510 ZC53.3 No description available WB:WBGene00022511 ZC53.4 Enriched in AFD based on RNA-seq studies. Is affected by several genes including csr-1; set-2; and let-418 based on RNA-seq studies. WB:WBGene00022512 dot-1.5 Predicted to enable histone H3K79 methyltransferase activity. Predicted to be involved in DNA damage checkpoint signaling and DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in acute biphenotypic leukemia. Is an ortholog of human DOT1L (DOT1 like histone lysine methyltransferase). WB:WBGene00022514 ZC64.1 No description available WB:WBGene00022515 ttr-48 Predicted to be located in cell surface and extracellular region. WB:WBGene00022516 mtx-2 Predicted to be involved in mitochondrion organization. Located in mitochondrion. Is an ortholog of human MTX2 (metaxin 2). WB:WBGene00022517 ZC123.1 Expressed in hypodermis. WB:WBGene00022518 zfh-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in body wall musculature; enteric muscle; nerve ring; neurons; and vulval muscle. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of human ZFHX3 (zinc finger homeobox 3) and ZFHX4 (zinc finger homeobox 4). WB:WBGene00022519 cdk-14 Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in regulation of transcription involved in G1/S transition of mitotic cell cycle. Predicted to be located in cytosol and nucleus. Is an ortholog of human CDK14 (cyclin dependent kinase 14) and CDK15 (cyclin dependent kinase 15). WB:WBGene00022520 ZC132.1 No description available WB:WBGene00022521 ZC132.2 Enriched in neurons based on tiling array studies. Is affected by several genes including eat-2; clk-1; and prg-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022522 ZC132.3 Predicted to be located in membrane. WB:WBGene00022523 ZC132.4 No description available WB:WBGene00022524 ZC132.5 No description available WB:WBGene00022526 ZC132.8 Enriched in neurons based on tiling array studies. Is affected by several genes including sir-2.1; clk-1; and etr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including resveratrol; Acrylamide; and dafa#1 based on microarray studies. WB:WBGene00022527 ZC132.9 Predicted to be located in membrane. WB:WBGene00022528 srt-13 Predicted to be located in membrane. WB:WBGene00022529 srt-14 Predicted to be located in membrane. WB:WBGene00022530 ZC155.2 Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be located in nucleus. Expressed in cholinergic neurons; head neurons; and tail neurons. WB:WBGene00022531 morc-1 Enables topological DNA co-entrapment activity. Involved in DNA topological change. Located in nuclear body. Expressed in somatic cell. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2Z. Is an ortholog of human MORC1 (MORC family CW-type zinc finger 1). WB:WBGene00022532 ZC155.4 Predicted to enable glycerophosphodiester phosphodiesterase activity. Predicted to be involved in N-acylethanolamine metabolic process; ethanolamine metabolic process; and phospholipid metabolic process. Predicted to be located in plasma membrane. Is an ortholog of human GDE1 (glycerophosphodiester phosphodiesterase 1). WB:WBGene00022533 cutl-19 Located in Golgi apparatus. WB:WBGene00022534 syx-16 Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; vesicle docking; and vesicle fusion. Predicted to be located in endomembrane system. Predicted to be part of SNARE complex. Human ortholog(s) of this gene implicated in pseudohypoparathyroidism type IB. Is an ortholog of human STX16 (syntaxin 16). WB:WBGene00022536 ZC178.2 Predicted to be involved in negative regulation of cell adhesion. Predicted to be located in plasma membrane. WB:WBGene00022537 ZC190.2 Predicted to be located in membrane. WB:WBGene00022538 ZC190.4 Predicted to enable mRNA binding activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in P-body. Is an ortholog of human SAMD4B (sterile alpha motif domain containing 4B). WB:WBGene00022539 ZC190.5 Predicted to be located in membrane. WB:WBGene00022540 ZC190.6 Predicted to be located in membrane. WB:WBGene00022541 ZC190.7 Predicted to be located in membrane. WB:WBGene00022542 ZC190.8 Predicted to be located in membrane. WB:WBGene00022544 ZC190.10 Enriched in NSM and neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including Alovudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00022545 ZC196.1 Enriched in OLL and PVD based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022546 ZC196.2 Predicted to enable FFAT motif binding activity. Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum-plasma membrane tethering. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 8 and autosomal dominant adult-onset proximal spinal muscular atrophy. Is an ortholog of human VAPA (VAMP associated protein A) and VAPB (VAMP associated protein B and C). WB:WBGene00022547 ZC196.3 Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; Mercuric Chloride; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF713) and Protein of unknown function DUF713. WB:WBGene00022548 ZC196.4 Enriched in AWC; coelomocyte; hypodermis; intestine; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Mercuric Chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF713) and Protein of unknown function DUF713. WB:WBGene00022549 ZC196.5 Predicted to be located in membrane. WB:WBGene00022550 droe-8 Enriched in cephalic sheath cell; muscle cell; neurons; and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; Mercuric Chloride; and procyanidin based on microarray and RNA-seq studies. WB:WBGene00022551 ZC196.8 Predicted to be located in membrane. WB:WBGene00022552 ZC196.9 Predicted to be located in membrane. WB:WBGene00022553 srlf-29 Is affected by several genes including sir-2.1; hpl-2; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is affected by Chlorpyrifos; Ag nanoparticles; and nitroguanidine based on microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00022554 duxl-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in coelomocyte; excretory cell; gonad; and spermatheca. WB:WBGene00022555 btb-12 Enriched in germ line and muscle cell based on RNA-seq and microarray studies. Is affected by several genes including daf-2; sir-2.1; and csr-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00022556 ZC204.6 Enriched in male based on RNA-seq studies. Is affected by several genes including sir-2.1; tph-1; and cat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022557 fbxb-15 Enriched in several structures, including ABalaaaarl; ABalaaaarr; AIA; GLR; and amphid neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00022558 fbxb-21 Enriched in MSaapaapa and MSpapaapa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00022559 fbxb-20 Enriched in PLML; PLMR; and pharyngeal muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00022560 fbxb-16 Enriched in ABalpppapa; ABpraaaapa; GLR; body wall muscle cell; and excretory system based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00022561 btb-13 Enriched in several structures, including ABalaaaarl; ABalaaaarr; MSaapapa; MSpapapa; and NSM based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; Rifampin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022562 ZC204.12 Expressed in head neurons and pharynx. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and Phosphorylation site. WB:WBGene00022563 ZC204.13 Enriched in ABprpapppa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and hpl-2 based on microarray and RNA-seq studies. Is affected by Colistin based on microarray studies. WB:WBGene00022564 ZC204.14 Enriched in several structures, including ABalppppaa; ABplpaaaap; ABpraaapaa; NSM; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including 1-methylnicotinamide; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022565 ZC239.2 Enriched in neurons based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; sek-1; and mir-34 based on microarray and RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and tetrabromobisphenol A based on RNA-seq and microarray studies. WB:WBGene00022566 ZC239.3 Predicted to be involved in protein homooligomerization. Predicted to be located in membrane. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00022567 ZC239.4 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00022568 ZC239.5 Predicted to be involved in protein homooligomerization. Predicted to be located in membrane. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00022569 ZC239.6 Predicted to be involved in protein homooligomerization. WB:WBGene00022570 sdz-35 Acts upstream of or within IRE1-mediated unfolded protein response and PERK-mediated unfolded protein response. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00022571 ZC239.13 Predicted to be involved in protein homooligomerization. WB:WBGene00022572 ZC239.14 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00022573 ZC239.15 Predicted to be involved in protein homooligomerization. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00022574 ZC239.16 Predicted to be involved in protein homooligomerization. Predicted to be located in membrane. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00022575 ZC239.17 Predicted to be involved in protein homooligomerization. Predicted to be located in membrane. Is an ortholog of human TNFAIP1 (TNF alpha induced protein 1). WB:WBGene00022576 ZC250.2 Predicted to enable acetylglucosaminyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Peters plus syndrome. Is an ortholog of human B3GLCT (beta 3-glucosyltransferase). WB:WBGene00022577 nstp-3 Predicted to enable UDP-galactose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport and carbohydrate transport. Predicted to be located in Golgi membrane. WB:WBGene00022578 ZC262.1 Is affected by several genes including rrf-3; aak-2; and isp-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including aldicarb; resveratrol; and Chlorpyrifos based on microarray and RNA-seq studies. WB:WBGene00022579 ZC262.2 Enriched in OLL; PVD; germ line; and intestine based on microarray and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-7 based on RNA-seq; proteomic; and microarray studies. Is affected by six chemicals including aldicarb; rotenone; and paraquat based on microarray and RNA-seq studies. Human RSRC2 enables RNA binding activity. Is predicted to encode a protein with the following domains: Small acidic protein-like domain; Small acidic protein family; and Phosphorylation site. Is an ortholog of human RSRC2 (arginine and serine rich coiled-coil 2). WB:WBGene00022580 iglr-2 Predicted to be located in membrane. Expressed in gonadal sheath cell and intestine. WB:WBGene00022581 ZC262.4 Enriched in AIML; AIMR; DVA; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; csr-1; and mdt-15 based on RNA-seq and microarray studies. Is affected by eight chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022582 ZC262.5 Predicted to enable proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1). Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Is an ortholog of human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2). WB:WBGene00022583 mrps-18A Predicted to enable small ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS18A (mitochondrial ribosomal protein S18A). WB:WBGene00022584 ZC266.1 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00022586 ZC308.4 Enriched in several structures, including ABplpppaaa; BAG; germ line; male distal tip cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercury hydroxide; rotenone; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00022587 ZC317.1 Enriched in NSM and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Atrazine; cadmium; and fluoranthene based on microarray studies. WB:WBGene00022588 ZC317.2 Predicted to be located in membrane. WB:WBGene00022589 ZC317.6 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00022590 ZC317.7 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-16; glp-1; and hsf-1 based on RNA-seq; microarray; and tiling array studies. Is affected by fifteen chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq and microarray studies. WB:WBGene00022591 cuti-1 Located in cytoplasm. Expressed in anus; excretory pore; hypodermis; and vulva. WB:WBGene00022592 klu-2 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of human ZNF740 (zinc finger protein 740). WB:WBGene00022593 ZC328.3 Predicted to enable sterol binding activity and sterol transfer activity. Predicted to be involved in intracellular sterol transport. Predicted to be located in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. Expressed in head. Is an ortholog of human GRAMD1C (GRAM domain containing 1C). WB:WBGene00022594 ZC328.5 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022596 ZC395.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00022597 ZC395.5 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalaapppa; ABalapaapa; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by thirty-two chemicals including methylmercuric chloride; rotenone; and mianserin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022598 ztf-8 Involved in double-strand break repair. Located in condensed chromosome and nucleolus. Expressed in several structures, including dorsal nerve cord; gonad; head muscle; head neurons; and intestine. WB:WBGene00022599 daf-41 Predicted to enable Hsp90 protein binding activity and protein-folding chaperone binding activity. Predicted to be involved in chaperone-mediated protein complex assembly and protein folding. Located in myofibril. Expressed in several structures, including amphid neurons; anal depressor muscle; phasmid neurons; touch receptor neurons; and vulva. Human ortholog(s) of this gene implicated in atherosclerosis; breast cancer; and oligodendroglioma. Is an ortholog of human PTGES3 (prostaglandin E synthase 3). WB:WBGene00022600 ZC395.11 Enriched in NSM and neurons based on tiling array and RNA-seq studies. Is affected by ifg-1 based on microarray studies. Is affected by Humic Substances based on microarray studies. WB:WBGene00022601 ZC404.1 Enriched in head mesodermal cell; neurons; and ventral nerve cord based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Rifampin; allantoin; and cadmium based on RNA-seq and microarray studies. WB:WBGene00022603 gck-2 Predicted to enable MAP kinase kinase kinase kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm. Expressed in several structures, including embryonic cell and vulval precursor cell. Used to study ciliopathy. Is an ortholog of human MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3) and MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5). WB:WBGene00022604 dmsr-10 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00022605 dmsr-11 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00022606 dmsr-9 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00022608 madf-9 Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. WB:WBGene00022609 ZC416.2 Predicted to be located in plasma membrane. WB:WBGene00022610 ltah-1.2 Predicted to enable aminopeptidase activity and epoxide hydrolase activity. Involved in negative regulation of fatty acid transport; regulation of lipid storage; and regulation of peptide transport. Predicted to be located in cytosol. Is an ortholog of human LTA4H (leukotriene A4 hydrolase). WB:WBGene00022611 ZC449.1 Enriched in several structures, including ABplpppaaa; germline precursor cell; hypodermis; neurons; and retrovesicular ganglion based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including methylmercury hydroxide; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00022612 ZC449.2 Enriched in several structures, including Caaaaa; Caaaap; I6 neuron; arc ant V; and mechanosensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; stavudine; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00022613 sek-3 Predicted to enable MAP kinase kinase activity. Predicted to be involved in stress-activated MAPK cascade. WB:WBGene00022614 ZC449.4 Predicted to be located in membrane. WB:WBGene00022615 ZC449.5 Predicted to be located in membrane. WB:WBGene00022616 hsd-3 Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in steroid biosynthetic process. Human ortholog(s) of this gene implicated in CHILD syndrome and CK syndrome. Is an ortholog of human SDR42E2 (short chain dehydrogenase/reductase family 42E, member 2). WB:WBGene00022617 ZC477.2 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00022618 ZC477.3 Predicted to be located in membrane. Is an ortholog of human CCDC51 (coiled-coil domain containing 51). WB:WBGene00022619 ZC477.4 Is affected by several genes including clk-1; spr-5; and egl-43 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Oligosaccharides; resveratrol; and Colistin based on microarray studies. WB:WBGene00022620 rde-8 Enables RNA endonuclease activity and mRNA binding activity. Involved in siRNA processing. Located in mutator focus. Expressed in germ line. WB:WBGene00022621 ZC477.7 Enriched in intestine and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-three chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily. WB:WBGene00022622 ZC477.10 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00022623 ZC487.1 Predicted to enable ATP binding activity. WB:WBGene00022624 ZC487.2 Predicted to be located in membrane. WB:WBGene00022627 ZC513.2 Predicted to enable lipid binding activity. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in atherosclerosis. Is an ortholog of human BPIFC (BPI fold containing family C). WB:WBGene00022628 ZC513.3 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. WB:WBGene00022629 algn-12 Predicted to enable alpha-1,6-mannosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ig. Is an ortholog of human ALG12 (ALG12 alpha-1,6-mannosyltransferase). WB:WBGene00022630 fbxa-223 Enriched in head mesodermal cell and in male based on RNA-seq studies. Is affected by several genes including eat-2; pmk-1; and npr-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including hydrogen sulfide; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00022631 nekl-2 Predicted to enable ion binding activity and protein kinase activity. Involved in molting cycle and positive regulation of endocytosis. Predicted to be located in cytoplasm. Expressed in hyp7 syncytium. Is an ortholog of human NEK3 (NIMA related kinase 3). WB:WBGene00022632 ZC581.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00022633 ZC581.3 Predicted to be located in membrane. WB:WBGene00022634 ZC581.7 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00022635 ZC581.9 Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-4. Is an ortholog of human SCYL2 (SCY1 like pseudokinase 2). WB:WBGene00022636 nhr-278 Is affected by clk-1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00022637 nhr-252 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00022638 scl-27 Predicted to be located in extracellular space. WB:WBGene00022639 nhr-253 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in ASEL; ASER; and neurons. Human ortholog(s) of this gene implicated in cholestasis (multiple); liver disease (multiple); and non-alcoholic steatohepatitis. Is an ortholog of human NR1H4 (nuclear receptor subfamily 1 group H member 4) and NR1I3 (nuclear receptor subfamily 1 group I member 3). WB:WBGene00022640 nhr-254 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00022641 ZK6.6 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00022642 lipl-5 Predicted to enable hydrolase activity, acting on ester bonds. Involved in defense response to Gram-negative bacterium; lipid homeostasis; and triglyceride catabolic process. Located in lysosome. Expressed in coelomocyte and intestine. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). WB:WBGene00022643 ZK6.8 Predicted to be located in membrane. Is an ortholog of human MFSD11 (major facilitator superfamily domain containing 11). WB:WBGene00022644 dod-19 Involved in innate immune response. Located in membrane raft. WB:WBGene00022645 irg-8 Involved in innate immune response. Located in membrane raft. WB:WBGene00022646 acl-9 Predicted to enable acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Predicted to be located in endoplasmic reticulum. Is an ortholog of human LCLAT1 (lysocardiolipin acyltransferase 1). WB:WBGene00022647 slc-17.1 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Located in sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in sialuria. Is an ortholog of human SLC17A5 (solute carrier family 17 member 5). WB:WBGene00022648 ZK54.3 Predicted to be located in membrane. WB:WBGene00022649 ZK84.1 Enriched in ABarppaapp; ABarpppapp; germ line; and seam cell based on proteomic and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by twenty-seven chemicals including hydrogen sulfide; rotenone; and sodium arsenite based on microarray; RNA-seq; and proteomic studies. WB:WBGene00022650 ZK84.2 Predicted to be located in membrane. WB:WBGene00022651 ZK84.4 Predicted to be located in membrane. WB:WBGene00022652 ZK84.5 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; D-glucose; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00022653 ZK105.1 Enriched in RIH; body wall musculature; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including Heme; Ethanol; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00022654 ZK105.3 Enriched in RID and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: STELLO-like and STELLO glycosyltransferases. WB:WBGene00022655 srsx-40 Predicted to be located in membrane. WB:WBGene00022656 ZK105.5 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by Cadmium Chloride and Ag nanoparticles based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00022657 ZK105.6 Enriched in AFD; RID; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by atracurium; paraquat; and Ketamine based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00022658 srh-188 Is affected by several genes including clk-1; lin-52; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00022660 ZK112.4 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and ain-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fluoranthene based on microarray studies. WB:WBGene00022662 acs-25 Enriched in several structures, including ABalappaap; ABalapppaa; CAN; coelomocyte; and pharynx based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and nhr-49 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including aldicarb; methylmercury hydroxide; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: ANL, N-terminal domain. WB:WBGene00022663 glrx-21 Predicted to enable protein-disulfide reductase activity. Predicted to be located in mitochondrion. Is an ortholog of human GLRX2 (glutaredoxin 2). WB:WBGene00022664 ZK121.2 Predicted to enable nucleic acid binding activity. Is an ortholog of human R3HDM2 (R3H domain containing 2). WB:WBGene00022665 ZK154.1 Enriched in AFD; hypodermis; seam cell; sensory neurons; and tail hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; microarray; and proteomic studies. Is affected by twenty chemicals including Ethanol; methylmercury hydroxide; and methylmercuric chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00022666 ZK154.4 Predicted to be located in secretory granule. Human ortholog(s) of this gene implicated in female reproductive organ cancer (multiple); invasive ductal carcinoma; and pre-eclampsia. Is an ortholog of human EBAG9 (estrogen receptor binding site associated antigen 9). WB:WBGene00022667 ZK154.5 Enriched in germ line; intestine; neurons; rectal epithelial cell; and rectum based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including D-glucose; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022668 ZK154.6 Predicted to be located in membrane. WB:WBGene00022669 ZK177.1 Enriched in several structures, including NSM; germ line; nerve ring neurons; rect_D; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including rotenone; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00022670 ZK177.2 Predicted to enable histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. WB:WBGene00022671 ZK177.3 Expressed in intestine. Is predicted to encode a protein with the following domains: Zinc finger C2H2-type and Zinc finger C2H2 superfamily. WB:WBGene00022672 npp-24 Predicted to be located in membrane. WB:WBGene00022673 ZK177.8 Predicted to enable dGTPase activity. Predicted to be involved in dGTP catabolic process. Predicted to be located in nucleus. Expressed in head and tail. Human ortholog(s) of this gene implicated in several diseases, including Aicardi-Goutieres syndrome; Chilblain lupus; and hepatitis B. Is an ortholog of human SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1). WB:WBGene00022674 ZK177.9 Enriched in GABAergic neurons; body wall muscle cell; coelomocyte; muscle cell; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; pie-1; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; D-glucose; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00022675 gbb-2 Enables G protein-coupled GABA receptor activity. Involved in G protein-coupled receptor signaling pathway; negative regulation of cholinergic synaptic transmission; and response to xenobiotic stimulus. Predicted to be located in plasma membrane. Predicted to be part of G protein-coupled receptor heterodimeric complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 59 and nicotine dependence. Is an ortholog of human GABBR2 (gamma-aminobutyric acid type B receptor subunit 2). WB:WBGene00022677 rfth-1 Predicted to be involved in glycolipid translocation. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation In. Is an ortholog of human RFT1 (RFT1 homolog). WB:WBGene00022678 sar-1 Predicted to enable GTPase activity. Involved in embryo development. Predicted to be located in endoplasmic reticulum exit site. Predicted to be part of COPII vesicle coat. Human ortholog(s) of this gene implicated in chylomicron retention disease. Is an ortholog of human SAR1A (secretion associated Ras related GTPase 1A) and SAR1B (secretion associated Ras related GTPase 1B). WB:WBGene00022679 ZK180.5 Enriched in several structures, including hypodermis; neurons; pharyngeal muscle cell; rectal epithelial cell; and somatic gonad precursor based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; quantitative PCR; tiling array; proteomic; and RNA-seq studies. Is affected by thirty-three chemicals including hydrogen sulfide; 1-methylnicotinamide; and nicotinic acid based on microarray; RNA-seq; and proteomic studies. WB:WBGene00022680 ZK180.6 Enriched in cholinergic neurons; mechanosensory neurons; rectal epithelial cell; and rectal gland cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by twenty-three chemicals including hydrogen sulfide; Nitric Oxide; and methylmercury hydroxide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022681 ZK185.1 Enriched in AINL; AINR; NSM; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; clk-1; and sma-2 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by Zidovudine; Doxycycline; and paraquat based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022682 ZK185.2 Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human SLC41A1 (solute carrier family 41 member 1) and SLC41A2 (solute carrier family 41 member 2). WB:WBGene00022683 ZK185.3 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and Caappd based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; dpy-10; and daf-12 based on microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including rotenone; multi-walled carbon nanotube; and levamisole based on RNA-seq and microarray studies. Human GLYAT enables glycine N-acyltransferase activity and glycine N-benzoyltransferase activity. Is predicted to encode a protein with the following domain: Acyl-CoA N-acyltransferase. Is an ortholog of human GLYAT (glycine-N-acyltransferase). WB:WBGene00022684 ZK250.1 No description available WB:WBGene00022685 ZK250.2 Enriched in AFD; AIM; Z1.p; Z4.a; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; lin-35; and csr-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; dafa#1; and adsorbable organic bromine compound based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00022686 ZK250.3 No description available WB:WBGene00022687 ZK250.4 No description available WB:WBGene00022688 math-47 Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00022689 math-48 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by methylmercuric chloride; Doxycycline; and paraquat based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00022690 math-49 Enriched in ALML; ALMR; NSM; PLML; and PLMR based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; Alovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00022691 math-50 Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Doxycycline; fluoranthene; and Chlorpyrifos based on RNA-seq and microarray studies. WB:WBGene00022692 ZK250.9 No description available WB:WBGene00022693 ZK250.10 No description available WB:WBGene00022694 gcna-1 Enables SUMO polymer binding activity. Involved in meiotic chromosome segregation and protein-DNA covalent cross-linking repair. Located in PML body and condensed chromosome. Expressed in Z2; Z3; and germ cell. Human ortholog(s) of this gene implicated in spermatogenic failure. Is an ortholog of human GCNA (germ cell nuclear acidic peptidase). WB:WBGene00022695 ZK328.6 Enriched in PLM and pharyngeal muscle cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; multi-walled carbon nanotube; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily and F-box domain. WB:WBGene00022696 ift-139 Predicted to be involved in intraciliary retrograde transport and protein localization to cilium. Predicted to be located in cytoplasm; cytoskeleton; and plasma membrane bounded cell projection. Predicted to be part of intraciliary transport particle A. Expressed in amphid neurons; ciliated neurons; head neurons; sensory neurons; and tail neurons. Used to study nephronophthisis. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 4; nephronophthisis 12; and spermatogenic failure 37. Is an ortholog of human TTC21A (tetratricopeptide repeat domain 21A) and TTC21B (tetratricopeptide repeat domain 21B). WB:WBGene00022697 cyy-1 Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity. Involved in negative regulation of synapse assembly; regulation of neuron remodeling; and regulation of terminal button organization. Located in axon and dendrite. Is an ortholog of human CCNY (cyclin Y) and CCNYL1 (cyclin Y like 1). WB:WBGene00022698 ZK353.2 Enriched in several structures, including ABplppppaa; MSpppaaa; anterior arcade cell; head mesodermal cell; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and aak-2 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein SUP-1-like and Protein of unknown function (DUF2650). WB:WBGene00022699 ZK353.3 Enriched in male based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including aldicarb; methylmercuric chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00022700 ZK353.4 Enriched in amphid sheath cell; neurons; and in male based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00022702 cutc-1 Predicted to enable copper ion binding activity. Involved in several processes, including egg-laying behavior; response to copper ion; and vulval development. Located in cell junction and striated muscle dense body. Is an ortholog of human CUTC (cutC copper transporter). WB:WBGene00022703 ubxn-4 Involved in positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress and ubiquitin-dependent ERAD pathway. Predicted to be located in endoplasmic reticulum. Is an ortholog of human UBXN4 (UBX domain protein 4). WB:WBGene00022704 ZK353.9 Predicted to be located in nucleus. Is an ortholog of human PITHD1 (PITH domain containing 1). WB:WBGene00022705 ZK354.2 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00022706 ZK354.3 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; germ line; muscle cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00022707 ZK354.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. WB:WBGene00022708 ZK354.7 Predicted to be located in cytoskeleton. WB:WBGene00022709 ZK354.8 Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of human PTPN9 (protein tyrosine phosphatase non-receptor type 9). WB:WBGene00022710 ZK354.9 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00022711 irld-63 Enriched in neurons based on RNA-seq studies. Is affected by several genes including let-60; sir-2.1; and alg-1 based on RNA-seq and microarray studies. Is affected by fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00022712 ZK355.2 Predicted to be located in membrane. WB:WBGene00022713 ZK355.3 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-four chemicals including cholesterol; lathosterol; and tryptophan based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022714 irld-64 Enriched in pharynx based on RNA-seq studies. Is affected by several genes including let-60; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by fluoranthene and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00022715 irld-65 Enriched in amphid sheath cell; neurons; and retrovesicular ganglion based on RNA-seq and microarray studies. Is affected by several genes including skn-1; csr-1; and unc-75 based on RNA-seq; microarray; and proteomic studies. Is affected by Sodium Chloride and Colistin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00022716 irld-66 Enriched in neurons based on RNA-seq studies. Is affected by csr-1 and rrf-2 based on RNA-seq and microarray studies. Is affected by tryptophan; resveratrol; and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00022717 hipr-1 Predicted to enable actin filament binding activity; anion binding activity; and clathrin binding activity. Involved in several processes, including cellular localization; defecation; and ultradian rhythm. Predicted to be located in clathrin-coated vesicle. Expressed in germ line; gonad; neurons; and pharynx. Is an ortholog of human HIP1 (huntingtin interacting protein 1) and HIP1R (huntingtin interacting protein 1 related). WB:WBGene00022718 ZK370.4 Predicted to enable lysophospholipase activity. Predicted to be involved in lipid catabolic process. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in several diseases, including Boucher-Neuhauser syndrome; Laurence-Moon syndrome; and Oliver-McFarlane syndrome. Is an ortholog of human PNPLA6 (patatin like phospholipase domain containing 6). WB:WBGene00022719 pdhk-2 Predicted to enable pyruvate dehydrogenase (acetyl-transferring) kinase activity. Predicted to be involved in regulation of glucose metabolic process. Located in perinuclear region of cytoplasm. Expressed in head neurons; intestine; pharynx; and vulval muscle. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease X-linked dominant 6. Is an ortholog of human PDK1 (pyruvate dehydrogenase kinase 1) and PDK4 (pyruvate dehydrogenase kinase 4). WB:WBGene00022720 ZK370.6 Enriched in body wall musculature; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00022721 ugtp-1 Predicted to enable pyrimidine nucleotide-sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport and pyrimidine nucleotide-sugar transmembrane transport. Located in Golgi medial cisterna and cortical granule. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIf. Is an ortholog of human SLC35A1 (solute carrier family 35 member A1). WB:WBGene00022722 tomm-70 Predicted to enable mitochondrion targeting sequence binding activity. Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in several processes, including positive regulation of interferon-beta production; protein targeting to mitochondrion; and regulation of defense response. Located in mitochondrion. Expressed in muscle cell; pharyngeal muscle cell; and tail. Human ortholog(s) of this gene implicated in congestive heart failure. Is an ortholog of human TOMM70 (translocase of outer mitochondrial membrane 70). WB:WBGene00022723 ZK380.2 Enriched in CEM; HOB; IL2 neuron; neurons; and ray neuron type B based on RNA-seq studies. Is affected by several genes including age-1; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00022724 ZK380.4 Enriched in NSM and neurons based on tiling array and RNA-seq studies. Is affected by several genes including csr-1; mex-1; and hda-1 based on tiling array and RNA-seq studies. Is affected by eight chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00022725 ZK381.2 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00022726 nhr-249 Predicted to be located in nucleus. WB:WBGene00022727 prkl-1 Predicted to enable zinc ion binding activity. Expressed in several structures, including QL; egg-laying apparatus; gonad; head; and somatic nervous system. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Is an ortholog of human PRICKLE2 (prickle planar cell polarity protein 2) and PRICKLE3 (prickle planar cell polarity protein 3). WB:WBGene00022728 ZK402.1 Enriched in ABalaaaala; ABalaapaaa; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by Testosterone based on microarray studies. WB:WBGene00022729 ZK402.2 Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00022730 ZK402.3 Enriched in several structures, including anterior hypodermis; germ line; interfacial epithelial cell; rectal gland cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by four chemicals including aldicarb; antimycin; and Humic Substances based on microarray and RNA-seq studies. WB:WBGene00022731 ZK402.5 Enriched in several structures, including ABplppppaa; ABprppppaa; germline precursor cell; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; glp-1; and let-60 based on RNA-seq and microarray studies. Is affected by twelve chemicals including stearic acid; sucrose; and Doxycycline based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00022732 ZK418.2 Enriched in sensory neurons and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-three chemicals including methylmercury hydroxide; nicotinic acid; and methylmercuric chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: SKP1/BTB/POZ domain superfamily. WB:WBGene00022733 tmem-17 Predicted to be involved in non-motile cilium assembly. Located in ciliary transition zone. Expressed in amphid neurons; ciliated neurons; inner labial neurons; outer labial neurons; and phasmid neurons. Is an ortholog of human TMEM17 (transmembrane protein 17). WB:WBGene00022734 ZK418.5 Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Is an ortholog of human TMEM147 (transmembrane protein 147). WB:WBGene00022735 ZK418.6 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00022736 ZK418.7 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00022737 tofu-7 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA processing and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleus. WB:WBGene00022738 fubl-2 Predicted to enable mRNA binding activity. Predicted to be involved in mRNA processing and regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); liver cirrhosis; and malignant astrocytoma. Is an ortholog of human FUBP1 (far upstream element binding protein 1); FUBP3 (far upstream element binding protein 3); and KHSRP (KH-type splicing regulatory protein). WB:WBGene00022739 toe-1 Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and positive regulation of transcription by RNA polymerase I. Predicted to be located in nucleolus. Predicted to be part of 90S preribosome; small-subunit processome; and t-UTP complex. Human ortholog(s) of this gene implicated in glioblastoma and pancreatic ductal carcinoma. Is an ortholog of human HEATR1 (HEAT repeat containing 1). WB:WBGene00022741 ZK430.5 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in meiotic chromosome separation. Predicted to be located in cytoplasm; microtubule cytoskeleton; and nucleus. Is an ortholog of human ESPL1 (extra spindle pole bodies like 1, separase). WB:WBGene00022742 dcaf-13 Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human DCAF13 (DDB1 and CUL4 associated factor 13). WB:WBGene00022743 mlt-7 Enables peroxidase activity. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle; nematode larval development; and post-embryonic body morphogenesis. Predicted to be located in extracellular space. Expressed in anterior hypodermis and hypodermal cell. WB:WBGene00022744 ZK470.1 Predicted to be involved in cellular response to reactive oxygen species and mitochondrial ribosome assembly. Predicted to be located in mitochondrion. Is an ortholog of human MPV17L2 (MPV17 mitochondrial inner membrane protein like 2). WB:WBGene00022745 ZK470.2 Enriched in several structures, including ABalpppppp; ABalppppppp; ABpraaappp; ABpraaapppp; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twelve chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022746 ZK470.4 Predicted to enable ATP binding activity. WB:WBGene00022747 ZK470.6 Enriched in arcade cell; muscle cell; and pharyngeal-intestinal valve based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including 1-methylnicotinamide; glycine; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00022748 oaz-1 Predicted to enable ornithine decarboxylase inhibitor activity. Predicted to be involved in positive regulation of protein catabolic process. Predicted to be located in cytoplasm and nucleus. Expressed in spermathecal-uterine valve cell. Is an ortholog of human OAZ1 (ornithine decarboxylase antizyme 1). WB:WBGene00022749 ZK484.3 Enriched in several structures, including ABalapaaaa; ABalappapa; ABarppaapp; germ line; and mechanosensory neurons based on proteomic; microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; let-7; and gld-1 based on microarray; proteomic; and RNA-seq studies. Is affected by six chemicals including paraquat; Capsaicin; and Hydrolyzable Tannins based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022750 tres-1 Expressed in several structures, including ABa; EMS; Psub1; Psub2; and gonad. Human TICRR enables chromatin binding activity. Is predicted to encode a protein with the following domain: Phosphorylation site. Is an ortholog of human TICRR (TOPBP1 interacting checkpoint and replication regulator). WB:WBGene00022751 msrp-2 Enriched in amphid sheath cell; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and age-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirty-three chemicals including Ethanol; 1-methylnicotinamide; and nicotinic acid based on RNA-seq and microarray studies. WB:WBGene00022752 ZK484.6 Predicted to enable phosphatase activity. Predicted to be located in cytoplasm. WB:WBGene00022753 ZK484.7 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00022754 nspd-1 Enriched in several structures, including AVK; amphid sheath cell; coelomocyte; intestine; and sperm based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-two chemicals including Ethanol; methylmercury hydroxide; and nicotinic acid based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Caenorhabditis elegans protein of unknown function (DUF780) and Protein of unknown function DUF780, Caenorhabditis species. WB:WBGene00022755 nhr-250 Is affected by several genes including ubc-9; wdr-5.1; and pmt-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022756 nhr-251 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00022757 ZK488.5 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00022758 ZK488.6 Predicted to enable glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in cytoplasm. WB:WBGene00022759 ZK546.2 Enriched in several structures, including ADE sheath cell; PLM; anterior ganglion; germ line; and intestine based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Zidovudine; paraquat; and Hydrolyzable Tannins based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine-rich repeat domain superfamily; Leucine-rich repeat, typical subtype; Leucine rich repeat; and Leucine-rich repeat. Is an ortholog of human LRRC57 (leucine rich repeat containing 57). WB:WBGene00022760 ZK546.3 Enriched in AVK; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on RNA-seq; microarray; and tiling array studies. Is affected by sixteen chemicals including Ethanol; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022761 ZK546.4 Predicted to be located in membrane. WB:WBGene00022762 ZK546.5 Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. WB:WBGene00022763 ZK546.7 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00022764 ZK546.8 No description available WB:WBGene00022765 gldi-11 Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in ribosomal large subunit biogenesis and ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Is an ortholog of human SURF6 (surfeit 6). WB:WBGene00022766 cblc-1 Enables cobalamin binding activity. Predicted to be involved in several processes, including cobalamin metabolic process; demethylation; and glutathione metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Is an ortholog of human MMACHC (metabolism of cobalamin associated C). WB:WBGene00022767 ZK563.2 Predicted to enable sodium:phosphate symporter activity. Predicted to be involved in sodium ion transmembrane transport and sodium-dependent phosphate transport. Predicted to be located in apical plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Fanconi renotubular syndrome 2; hereditary hypophosphatemic rickets with hypercalciuria; and hypophosphatemic nephrolithiasis/osteoporosis 1. Is an ortholog of human SLC34A2 (solute carrier family 34 member 2) and SLC34A3 (solute carrier family 34 member 3). WB:WBGene00022768 ZK563.3 No description available WB:WBGene00022769 sorf-1 Predicted to enable phosphatidylinositol 3-kinase regulator activity. Involved in organelle fusion and positive regulation of early endosome to late endosome transport. Located in early endosome and late endosome. Is an ortholog of human WDR91 (WD repeat domain 91). WB:WBGene00022770 acp-1 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in membrane. Is an ortholog of human ACP6 (acid phosphatase 6, lysophosphatidic). WB:WBGene00022771 ZK616.1 Predicted to enable mRNA binding activity. Predicted to be located in nucleus. WB:WBGene00022772 ZK616.2 Predicted to enable protein-disulfide reductase activity. Predicted to be involved in protein import into mitochondrial intermembrane space and protein maturation by protein folding. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human CHCHD4 (coiled-coil-helix-coiled-coil-helix domain containing 4). WB:WBGene00022773 ZK616.3 Predicted to enable protein-disulfide reductase activity. Predicted to be involved in protein import into mitochondrial intermembrane space and protein maturation by protein folding. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human CHCHD4 (coiled-coil-helix-coiled-coil-helix domain containing 4). WB:WBGene00022774 swsn-6 Predicted to enable chromatin binding activity. Predicted to be involved in nervous system development and regulation of transcription by RNA polymerase II. Predicted to be part of NuA4 histone acetyltransferase complex and SWI/SNF complex. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 76. Is an ortholog of human ACTL6B (actin like 6B). WB:WBGene00022775 ZK616.5 Enriched in germ line; germline precursor cell; head mesodermal cell; hypodermis; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00022776 perm-3 Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of EMC complex. Is an ortholog of human EMC4 (ER membrane protein complex subunit 4). WB:WBGene00022778 ZK616.8 Enriched in NSM; pm1; pm2; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by eleven chemicals including hydrogen sulfide; Ethanol; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: PLAT/LH2 domain superfamily. WB:WBGene00022780 ZK622.1 Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase). WB:WBGene00022781 pmt-1 Enables phosphoethanolamine N-methyltransferase activity. Involved in multicellular organism reproduction; nematode larval development; and phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline. Predicted to be located in cytosol. Expressed in seam cell. Used to study lipid metabolism disorder. WB:WBGene00022782 ZK622.4 Predicted to enable metal ion binding activity. WB:WBGene00022783 tomm-7 Involved in mitochondrion organization. Predicted to be located in mitochondrial outer membrane. Predicted to be part of mitochondrial outer membrane translocase complex. Expressed in intestine and pharynx. Is an ortholog of human TOMM7 (translocase of outer mitochondrial membrane 7). WB:WBGene00022785 kcmf-1 Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in synaptic signaling. Predicted to be located in plasma membrane. Is an ortholog of human KCMF1 (potassium channel modulatory factor 1). WB:WBGene00022786 ZK652.8 Expressed in head neurons; intestine; nervous system; and tail neurons. WB:WBGene00022787 tag-307 Predicted to enable DNA binding activity. Predicted to be involved in error-free translesion synthesis. Predicted to be located in mitochondrial nucleoid and nucleus. Is an ortholog of human POLDIP2 (DNA polymerase delta interacting protein 2). WB:WBGene00022788 slc-17.7 Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be located in membrane. WB:WBGene00022789 lron-2 Predicted to be located in membrane. Expressed in tail. Is an ortholog of human LRRC15 (leucine rich repeat containing 15). WB:WBGene00022790 ZK682.7 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppppapa; ABalppppppa; and ciliated neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including Tunicamycin; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00022791 ZK686.1 Enriched in PLM; germ line; hypodermis; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; D-glucose; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00022792 ZK686.2 Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be located in nucleus. Expressed in neurons. Is an ortholog of human DDX51 (DEAD-box helicase 51). WB:WBGene00022793 ZK686.3 Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Used to study bacterial infectious disease. Human ortholog(s) of this gene implicated in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia; autosomal recessive intellectual developmental disorder 7; and congenital disorder of glycosylation Icc. Is an ortholog of human MAGT1 (magnesium transporter 1) and TUSC3 (tumor suppressor candidate 3). WB:WBGene00022794 snu-23 Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex. Is an ortholog of human ZMAT2 (zinc finger matrin-type 2). WB:WBGene00022795 ZK686.5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00022796 ZK688.1 Enriched in IL socket cell; arc ant V; and dopaminergic neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including Rifampin; allantoin; and Chlorpyrifos based on RNA-seq and microarray studies. WB:WBGene00022797 best-24 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Expressed in head neurons; hypodermis; intestine; and nervous system. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). WB:WBGene00022798 fahd-1 Predicted to enable acetylpyruvate hydrolase activity. Located in mitochondrion. Expressed in body wall musculature; excretory canal; pharynx; and vulva. Is an ortholog of human FAHD1 (fumarylacetoacetate hydrolase domain containing 1). WB:WBGene00022799 ZK688.4 Enriched in ABplpapppa based on single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including metformin; Sirolimus; and paraquat based on RNA-seq and microarray studies. WB:WBGene00022800 ZK688.5 Predicted to enable misfolded protein binding activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be part of BAT3 complex. Human ortholog(s) of this gene implicated in gastrointestinal stromal tumor; lung non-small cell carcinoma; and osteoarthritis. Is an ortholog of human BAG6 (BAG cochaperone 6). WB:WBGene00022801 pcp-5 Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Expressed in body wall musculature. Is an ortholog of human PRCP (prolylcarboxypeptidase). WB:WBGene00022802 ZK688.7 Enriched in several structures, including ABalapaaaa; anterior ganglion; germ line; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00022803 ZK688.9 Predicted to be involved in TOR signaling. Predicted to be located in cytosol. Is an ortholog of human TIPRL (TOR signaling pathway regulator). WB:WBGene00022804 ZK697.1 Predicted to be located in membrane. WB:WBGene00022805 nhr-256 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00022806 ZK697.3 Is affected by rsr-2 based on tiling array studies. Is affected by resveratrol; Chlorpyrifos; and Diazinon based on microarray studies. WB:WBGene00022807 srab-25 Predicted to be located in membrane. Expressed in intestine. WB:WBGene00022808 ZK697.8 Predicted to enable hydroxyisourate hydrolase activity. Predicted to be involved in purine nucleobase metabolic process. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; colorectal adenoma; dystransthyretinemic hyperthyroxinemia; and gastrointestinal system cancer (multiple). Is an ortholog of human TTR (transthyretin). WB:WBGene00022809 ZK697.14 Predicted to enable oxidoreductase activity. Predicted to be located in cytoplasm. Is an ortholog of human CBR1 (carbonyl reductase 1) and CBR3 (carbonyl reductase 3). WB:WBGene00022810 ZK721.3 Enriched in B cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; pgl-1; and mex-3 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including rotenone; D-glucopyranose; and Psoralens based on RNA-seq studies. WB:WBGene00022811 ZK721.4 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00022812 uvs-1 Predicted to enable RNA polymerase II complex binding activity. Involved in response to UV and transcription-coupled nucleotide-excision repair. Predicted to be located in chromosome. Human ortholog(s) of this gene implicated in UV-sensitive syndrome. Is an ortholog of human UVSSA (UV stimulated scaffold protein A). WB:WBGene00022813 ZK742.3 Predicted to enable FMN binding activity and oxidoreductase activity. WB:WBGene00022814 ZK742.4 Predicted to enable FMN binding activity and oxidoreductase activity. WB:WBGene00022815 asic-1 Predicted to enable acid-sensing ion channel activity. Involved in positive regulation of dopamine secretion. Predicted to be located in plasma membrane. Expressed in XXX cell and neurons. Human ortholog(s) of this gene implicated in bronchiectasis (multiple) and renal tubular transport disease (multiple). Is an ortholog of human SCNN1B (sodium channel epithelial 1 subunit beta); SCNN1D (sodium channel epithelial 1 subunit delta); and SCNN1G (sodium channel epithelial 1 subunit gamma). WB:WBGene00022816 fbn-1 Predicted to enable calcium ion binding activity. Predicted to be located in membrane. Expressed in vulval cell. Used to study connective tissue disease. Human ortholog(s) of this gene implicated in several diseases, including CREST syndrome; aortic disease (multiple); and bone disease (multiple). Is an ortholog of human FBN1 (fibrillin 1); FBN2 (fibrillin 2); and FBN3 (fibrillin 3). WB:WBGene00022817 upp-1 Enables thymidine phosphorylase activity and uridine phosphorylase activity. Involved in thymidine metabolic process; uracil catabolic process; and uridine catabolic process. Predicted to be located in cytosol. Expressed in gonad; hypodermis; pharynx; and spermatheca. Is an ortholog of human UPP1 (uridine phosphorylase 1) and UPP2 (uridine phosphorylase 2). WB:WBGene00022818 ZK783.3 Enriched in NSM; seam cell; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; glycine; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00022820 ZK813.1 Enriched in anterior spermatheca; excretory cell; muscle cell; and posterior spermatheca based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty chemicals including Lithium Chloride; Heme; and Ethanol based on microarray and RNA-seq studies. WB:WBGene00022821 ZK813.2 Enriched in anterior spermatheca and posterior spermatheca based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by nineteen chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies. WB:WBGene00022822 ZK813.3 Expressed in spermatheca. WB:WBGene00022823 ZK813.4 Enriched in head mesodermal cell; muscle cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022824 ZK813.5 Predicted to enable G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to be located in membrane. WB:WBGene00022825 ZK816.1 Predicted to be located in membrane. WB:WBGene00022826 ZK816.3 Enriched in coelomocyte; excretory gland cell; and pharynx based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by hpl-2; daf-2; and egl-43 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00022827 nspg-4 Expressed in pharynx. WB:WBGene00022829 ZK867.2 Predicted to enable ionotropic glutamate receptor activity. Predicted to be involved in ionotropic glutamate receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00022830 ZK973.1 Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Is an ortholog of human SRBD1 (S1 RNA binding domain 1). WB:WBGene00022831 cec-10 Predicted to be involved in positive regulation of transcription involved in G1/S transition of mitotic cell cycle. Predicted to be part of MBF transcription complex and SBF transcription complex. WB:WBGene00022832 pdp-1 Predicted to enable [pyruvate dehydrogenase (lipoamide)] phosphatase activity. Predicted to be located in mitochondrion. Expressed in head muscle; head neurons; intestine; and tail neurons. Human ortholog(s) of this gene implicated in obesity and pyruvate decarboxylase deficiency. Is an ortholog of human PDP1 (pyruvate dehydrogenase phosphatase catalytic subunit 1) and PDP2 (pyruvate dehydrogenase phosphatase catalytic subunit 2). WB:WBGene00022833 ZK973.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Cry5B; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00022834 ZK973.8 Enriched in several structures, including ABalaapppp; ABalapaapp; ABalappppa; ABalppappp; and AVK based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including manganese chloride; mianserin; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1265; SKP1/BTB/POZ domain superfamily; and Protein of unknown function (DUF1265). WB:WBGene00022835 ZK973.9 Enriched in several structures, including ABplaapappp; ABpraapappp; NSM; germ line; and head ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by seven chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in synovial sarcoma. Human SS18 enables nuclear receptor coactivator activity. Is predicted to encode a protein with the following domains: SS18, N-terminal and SSXT protein (N-terminal region). Is an ortholog of human SS18 (SS18 subunit of BAF chromatin remodeling complex) and SS18L1 (SS18L1 subunit of BAF chromatin remodeling complex). WB:WBGene00022836 ZK973.11 Predicted to enable protein disulfide isomerase activity and protein-disulfide reductase activity. Predicted to be located in endoplasmic reticulum membrane. Expressed in head neurons; intestine; and nervous system. Is an ortholog of human TMX3 (thioredoxin related transmembrane protein 3). WB:WBGene00022837 ceh-45 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in I1L; I1R; MI neuron; pharynx; and spermatheca. Is an ortholog of human GSC (goosecoid homeobox). WB:WBGene00022838 ZK993.2 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. WB:WBGene00022840 ZK994.1 Enriched in intestine and in male based on RNA-seq and microarray studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022842 ZK994.6 Enriched in command interneuron and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including let-60; eat-2; and lin-35 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00022843 ZK1055.2 Predicted to be located in membrane. WB:WBGene00022845 ZK1055.4 Predicted to be located in membrane. WB:WBGene00022846 ZK1055.5 Enriched in M cell based on single-cell RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and alg-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00022847 ZK1055.6 Enriched in AVA; coelomocyte; intestine; sensory neurons; and somatic gonad precursor based on microarray; tiling array; and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including aldicarb; methylmercuric chloride; and Zidovudine based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4140; Domain of unknown function (DUF4139); Conserved hypothetical protein CHP02231; Domain of unknown function DUF4139; and N-terminal domain of unknown function (DUF4140). WB:WBGene00022848 ZK1055.7 Involved in innate immune response. WB:WBGene00022849 acs-6 Predicted to enable CoA-ligase activity. WB:WBGene00022850 ZK1127.3 Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Is an ortholog of human MRGBP (MRG domain binding protein). WB:WBGene00022851 ZK1127.4 Predicted to be located in nucleus. Is an ortholog of human BCCIP (BRCA2 and CDKN1A interacting protein). WB:WBGene00022852 ZK1127.5 Predicted to enable RNA endonuclease activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human RCL1 (RNA terminal phosphate cyclase like 1). WB:WBGene00022853 ZK1127.6 Enriched in AB and germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; proteomic; and microarray studies. Is affected by nine chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00022854 cin-4 Predicted to enable ATP binding activity; DNA binding activity; and DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity. Predicted to be involved in resolution of meiotic recombination intermediates and sister chromatid segregation. Predicted to be located in nucleus. Is an ortholog of human TOP2B (DNA topoisomerase II beta). WB:WBGene00022855 tcer-1 Predicted to enable RNA polymerase binding activity and transcription coregulator activity. Predicted to be involved in DNA-templated transcription. Located in nuclear periphery. Expressed in several structures, including germ cell; gonad; hypodermal cell; intestinal cell; and somatic cell. Is an ortholog of human TCERG1 (transcription elongation regulator 1). WB:WBGene00022856 cth-2 Predicted to enable cystathionine gamma-lyase activity and pyridoxal phosphate binding activity. Predicted to be involved in cysteine biosynthetic process via cystathionine and transsulfuration. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in cystathioninuria. Is an ortholog of human CTH (cystathionine gamma-lyase). WB:WBGene00022857 ZK1127.12 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalppppppp; PLM; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; sir-2.1; and pmk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; rotenone; and stavudine based on microarray and RNA-seq studies. WB:WBGene00022858 ZK1193.2 Enriched in several structures, including ABplpppaaa; ABprpppaaa; gonadal sheath cell; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; proteomic; and RNA-seq studies. Is affected by twenty-five chemicals including Ethanol; methylmercuric chloride; and Mercuric Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: von Willebrand factor A-like domain superfamily; von Willebrand factor, type A; and von Willebrand factor type A domain. WB:WBGene00022861 dve-1 Enables DNA-binding transcription activator activity, RNA polymerase II-specific; enzyme binding activity; and protein-folding chaperone binding activity. Involved in embryo development; mitochondrial unfolded protein response; and regulation of innate immune response. Located in cytosol and nucleus. Part of chromatin and transcription regulator complex. Expressed in several structures, including neurons; rectum; somatic nervous system; tail; and vulva. Human ortholog(s) of this gene implicated in SATB2-associated syndrome. Is an ortholog of human SATB1 (SATB homeobox 1) and SATB2 (SATB homeobox 2). WB:WBGene00022862 ZK1236.1 Predicted to enable mitochondrial ribosome binding activity. Predicted to be involved in positive regulation of translation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 40. Is an ortholog of human GUF1 (GTP binding elongation factor GUF1). WB:WBGene00022863 ZK1236.4 No description available WB:WBGene00022864 ZK1236.5 Enriched in NSM; germ line; and intestine based on RNA-seq and microarray studies. Is affected by several genes including hsf-1; let-7; and gld-1 based on proteomic; RNA-seq; and microarray studies. Is affected by seven chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00022865 ufbp-1 Located in nucleus. Expressed in head neurons. Used to study early infantile epileptic encephalopathy. Is an ortholog of human DDRGK1 (DDRGK domain containing 1). WB:WBGene00022866 ZK1240.1 Predicted to enable zinc ion binding activity. WB:WBGene00022867 ZK1240.2 Predicted to enable zinc ion binding activity. Is an ortholog of human TRIM13 (tripartite motif containing 13) and TRIM59 (tripartite motif containing 59). WB:WBGene00022868 ZK1240.3 Predicted to enable zinc ion binding activity. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; Sweet syndrome; and hematologic cancer (multiple). Is an ortholog of several human genes including MEFV (MEFV innate immunity regulator, pyrin); TRIM21 (tripartite motif containing 21); and TRIM27 (tripartite motif containing 27). WB:WBGene00022869 ZK1240.4 Enriched in CANL; CANR; and NSM based on tiling array and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and nhr-49 based on microarray and RNA-seq studies. Is affected by four chemicals including Zidovudine; paraquat; and bortezomib based on RNA-seq and microarray studies. WB:WBGene00022870 ZK1240.5 Predicted to enable zinc ion binding activity. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; Sweet syndrome; and hematologic cancer (multiple). Is an ortholog of several human genes including MEFV (MEFV innate immunity regulator, pyrin); TRIM21 (tripartite motif containing 21); and TRIM27 (tripartite motif containing 27). WB:WBGene00022871 ZK1240.6 Predicted to enable zinc ion binding activity. WB:WBGene00022872 ZK1240.8 Predicted to enable zinc ion binding activity. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; Sweet syndrome; and hematologic cancer (multiple). Is an ortholog of several human genes including MEFV (MEFV innate immunity regulator, pyrin); TRIM21 (tripartite motif containing 21); and TRIM27 (tripartite motif containing 27). WB:WBGene00022873 ZK1240.9 Predicted to enable zinc ion binding activity. Is an ortholog of human TRIM74 (tripartite motif containing 74). WB:WBGene00022874 nep-25 Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. WB:WBGene00022875 ZK1248.4 Is affected by several genes including daf-2; age-1; and eat-2 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by five chemicals including Tunicamycin; Cry5B; and resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00022876 ZK1248.5 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; age-1; and dpy-10 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty-three chemicals including nicotinic acid; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF1248 and Protein of unknown function (DUF1248). WB:WBGene00022877 wago-5 Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Predicted to be involved in obsolete RNA phosphodiester bond hydrolysis, endonucleolytic. WB:WBGene00022880 tbc-2 Enables GTPase activator activity. Involved in positive regulation of early endosome to late endosome transport and regulation of presynaptic dense core granule exocytosis. Located in cholinergic synapse and late endosome. Expressed in gonadal sheath cell; hypodermis; intestine; and pharyngeal muscle cell. Is an ortholog of human TBC1D2 (TBC1 domain family member 2). WB:WBGene00022881 ZK1248.11 Predicted to enable SUMO ligase activity. Predicted to be involved in double-strand break repair via homologous recombination and protein sumoylation. Predicted to be located in nucleus. Predicted to be part of Smc5-Smc6 complex. Human ortholog(s) of this gene implicated in Seckel syndrome 10. Is an ortholog of human NSMCE2 (NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase). WB:WBGene00022882 gtap-1 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalppppaa; ABplpppaapa; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; glp-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by nine chemicals including manganese chloride; Zidovudine; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00022883 ZK1248.15 Predicted to be located in nucleus. Is an ortholog of human SWT1 (SWT1 RNA endoribonuclease homolog). WB:WBGene00022884 ZK1248.17 Enriched in AVK; DD neuron; Z1.p; Z4.a; and male distal tip cell based on RNA-seq and microarray studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including multi-walled carbon nanotube; nicotine; and metformin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00022885 ZK1248.19 Predicted to enable beta-catenin binding activity. Is an ortholog of human LZIC (leucine zipper and CTNNBIP1 domain containing). WB:WBGene00022886 ZK1290.1 Enriched in male-specific anatomical entity; neurons; and in male based on RNA-seq and microarray studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00022887 ZK1290.5 Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. WB:WBGene00022888 rnh-1.1 Enables RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer. WB:WBGene00022889 ZK1290.7 Predicted to be located in membrane. WB:WBGene00022890 fbxa-224 Enriched in NSM; pm3; pm4; and pm5 based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00022891 ZK1290.10 Enriched in intestine; pharyngeal muscle cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including tryptophan; bisphenol A; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: ShKT domain. WB:WBGene00022892 ZK1290.11 Enriched in ABplppaapa; ABprppaapa; body wall musculature; male-specific anatomical entity; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00022893 ZK1290.13 Predicted to be located in membrane. WB:WBGene00022894 B0212.t1 No description available WB:WBGene00022895 B0213.18 Is affected by ins-11 and hmg-3 based on RNA-seq studies. WB:WBGene00022896 B0228.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00022897 B0244.t1 No description available WB:WBGene00022898 B0244.t2 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00022899 B0244.t3 Is affected by daf-2 based on microarray studies. WB:WBGene00022900 B0344.t1 No description available WB:WBGene00022901 B0344.t2 No description available WB:WBGene00022902 B0344.t3 No description available WB:WBGene00022903 B0350.t1 No description available WB:WBGene00022904 C01B12.9 Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including rotenone; Tunicamycin; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00022905 C02F12.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00022906 C03F11.t1 No description available WB:WBGene00022907 C04A2.t1 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00022908 C04E7.t1 No description available WB:WBGene00022909 C04F2.t1 No description available WB:WBGene00022910 C05D2.11 Enriched in body wall musculature; muscle cell; sensory neurons; and somatic gonad precursor based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by four chemicals including rotenone; antimycin; and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00022911 C05G6.t1 No description available WB:WBGene00022912 C06E4.t1 No description available WB:WBGene00022913 C06G1.t1 No description available WB:WBGene00022914 C06G1.t2 No description available WB:WBGene00022915 C06G1.t3 No description available WB:WBGene00022916 C06G1.t4 Is affected by daf-2 based on microarray studies. WB:WBGene00022917 C06G4.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00022918 C09B7.3 Is affected by daf-12 and hpl-2 based on tiling array studies. WB:WBGene00022919 C09B7.4 Enriched in neurons based on RNA-seq studies. Is affected by daf-12 and rsr-2 based on tiling array studies. WB:WBGene00022920 C09B9.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00022921 C10G8.t1 No description available WB:WBGene00022922 C12D12.7 Is affected by several genes including sir-2.1; met-2; and spr-5 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00022923 C14B9.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00022924 C14B9.t2 Is affected by daf-12 and hmg-3 based on tiling array and RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00022925 C14F11.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00022926 C16B8.5 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by rsr-2 and camt-1 based on tiling array and RNA-seq studies. WB:WBGene00022927 C16B8.t1 Is affected by hlh-26 based on RNA-seq studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00022928 C16B8.t2 Is affected by paraquat based on RNA-seq studies. WB:WBGene00022929 C16B8.t3 No description available WB:WBGene00022930 C16C8.t1 No description available WB:WBGene00022931 C16C8.t2 No description available WB:WBGene00022932 C16D9.10 Enriched in germ line based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00022933 C16D9.t2 No description available WB:WBGene00022934 C16D9.t3 No description available WB:WBGene00022935 C16D9.t4 No description available WB:WBGene00022936 C16H3.t1 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00022937 C16H3.t2 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00022938 C18A11.t1 No description available WB:WBGene00022939 C18A11.t2 No description available WB:WBGene00022940 C23H5.10 Enriched in neurons based on RNA-seq studies. Is affected by unc-39 and nfki-1 based on RNA-seq studies. WB:WBGene00022941 C25F6.t1 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00022942 C25F6.t2 No description available WB:WBGene00022943 C25F6.t3 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00022944 C25F6.t4 No description available WB:WBGene00022945 C27A2.t1 No description available WB:WBGene00022946 C27A12.t1 Is affected by meg-3 and meg-4 based on RNA-seq studies. WB:WBGene00022947 C28G1.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00022948 C28G1.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00022949 C28G1.t3 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00022950 C28G1.t4 Is affected by daf-12 based on tiling array studies. WB:WBGene00022951 C30E1.9 Enriched in neurons and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and sek-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including 1-methylnicotinamide; rotenone; and paraquat based on RNA-seq and microarray studies. WB:WBGene00022952 C30E1.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00022953 C35E7.t1 No description available WB:WBGene00022954 C36C9.t2 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00022955 C37A2.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00022956 C39D10.t1 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00022957 C39D10.t2 No description available WB:WBGene00022958 C42D8.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00022959 C43G2.t1 Is affected by daf-12 and mrps-5 based on tiling array and RNA-seq studies. WB:WBGene00022960 C43G2.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00022961 C44B7.t1 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00022962 C48C5.t1 No description available WB:WBGene00022963 C48C5.t2 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00022964 C48C5.t3 No description available WB:WBGene00022965 C48C5.t4 No description available WB:WBGene00022966 C52E12.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00022967 C52E12.t3 No description available WB:WBGene00022968 C55F2.3 Enriched in neurons based on RNA-seq studies. Is affected by blmp-1 based on RNA-seq studies. WB:WBGene00022969 C56G3.t1 No description available WB:WBGene00022970 CD4.10 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq studies. WB:WBGene00022971 D1009.t1 Is affected by daf-2 based on RNA-seq and microarray studies. WB:WBGene00022972 D1009.t2 No description available WB:WBGene00022973 E01H11.t1 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00022974 E03E2.t1 No description available WB:WBGene00022975 E03E2.t2 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00022976 E03E2.t3 No description available WB:WBGene00022977 F01G12.t1 No description available WB:WBGene00022978 F02E11.t1 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00022979 F08F1.t1 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00022980 F08F1.t2 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00022981 F08F1.t3 Is affected by daf-12 based on tiling array studies. WB:WBGene00022982 F09E10.10 Is affected by several genes including daf-16; daf-2; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; silicon dioxide nanoparticle; and Colistin based on RNA-seq and microarray studies. WB:WBGene00022983 F10C1.t1 Is affected by daf-2 and pptr-1 based on microarray and RNA-seq studies. WB:WBGene00022984 F10C1.t2 No description available WB:WBGene00022985 F11H8.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00022986 F12D9.t1 No description available WB:WBGene00022987 F12D9.t2 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00022988 F12D9.t3 No description available WB:WBGene00022989 F12D9.t4 No description available WB:WBGene00022990 F12D9.t5 No description available WB:WBGene00022991 F12D9.t6 No description available WB:WBGene00022992 F14B8.t1 No description available WB:WBGene00022993 F15A8.t1 No description available WB:WBGene00022994 F15A8.t2 No description available WB:WBGene00022995 F18C5.t1 Is affected by daf-12 and etr-1 based on tiling array and RNA-seq studies. WB:WBGene00022996 F18G5.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00022997 F18G5.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00022998 F22B7.t1 Is affected by adr-1 based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00022999 F22B7.t2 No description available WB:WBGene00023000 F22B7.t3 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00023001 F22B7.t4 Is affected by clk-1 based on microarray studies. WB:WBGene00023002 F22B7.t5 No description available WB:WBGene00023003 F22F1.t1 No description available WB:WBGene00023004 F22F1.t2 Is affected by daf-12 based on tiling array studies. WB:WBGene00023005 F22F1.t3 Is affected by daf-12 based on tiling array studies. WB:WBGene00023006 F22F1.t4 Is affected by daf-12 based on tiling array studies. WB:WBGene00023007 F22F1.t5 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00023008 F22F1.t6 Is affected by daf-12 based on tiling array studies. WB:WBGene00023009 F22F1.t7 Is affected by daf-12 based on tiling array studies. WB:WBGene00023010 F22F1.t8 Is affected by daf-12 based on tiling array studies. WB:WBGene00023011 F22F1.t9 Is affected by daf-12 based on tiling array studies. WB:WBGene00023012 F22H10.t1 Is affected by tdp-1; hmg-3; and stt-3 based on RNA-seq studies. Is affected by Ethanol and paraquat based on RNA-seq studies. WB:WBGene00023013 F25F6.t1 No description available WB:WBGene00023014 F25F6.t2 No description available WB:WBGene00023015 F27B10.t1 No description available WB:WBGene00023016 rte-3 No description available WB:WBGene00023017 F27E11.t1 No description available WB:WBGene00023018 F28F5.t1 No description available WB:WBGene00023019 F29C4.t1 No description available WB:WBGene00023020 F30H5.4 Enriched in AFD based on RNA-seq studies. Is affected by several genes including sek-1; pgl-1; and cep-1 based on RNA-seq studies. Is affected by Zidovudine based on RNA-seq studies. WB:WBGene00023021 F32A5.9 Enriched in anterior spermatheca and posterior spermatheca based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; Cry5B; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00023022 F32A6.t1 No description available WB:WBGene00023023 F33D11.t1 No description available WB:WBGene00023024 F33D11.t2 Is affected by clk-1 based on microarray studies. WB:WBGene00023025 F33G12.t1 Is affected by elli-1 and daf-2 based on microarray studies. WB:WBGene00023026 F35A5.t1 No description available WB:WBGene00023027 F35H10.12 Is affected by prg-1 and clk-1 based on RNA-seq and microarray studies. WB:WBGene00023028 F36D4.t1 No description available WB:WBGene00023029 F36D4.t2 No description available WB:WBGene00023030 F36H12.18 Is affected by several genes including daf-2; eat-2; and prg-1 based on RNA-seq and microarray studies. Is affected by Colistin based on microarray studies. WB:WBGene00023031 F37A4.t1 No description available WB:WBGene00023032 F38E9.t1 No description available WB:WBGene00023033 F38E9.t2 Is affected by clk-1 based on microarray studies. WB:WBGene00023034 F38G1.t1 No description available WB:WBGene00023035 F38G1.t2 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00023036 F39E9.10 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00023037 F40H6.t1 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00023038 F41A4.t1 No description available WB:WBGene00023039 F41B5.11 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00023040 F41D9.t1 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00023041 F41D9.t2 No description available WB:WBGene00023042 F41D9.t3 Is affected by daf-12 based on tiling array studies. WB:WBGene00023043 F41D9.t4 No description available WB:WBGene00023044 F42A10.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00023045 F42A10.t2 Is affected by daf-12 based on tiling array studies. WB:WBGene00023046 F42H10.t1 No description available WB:WBGene00023047 F43C9.t1 No description available WB:WBGene00023048 F43E12.t1 No description available WB:WBGene00023049 F44A2.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00023050 F46G11.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00023051 F46G11.t2 Is affected by daf-12 based on tiling array studies. WB:WBGene00023052 F47E1.t1 No description available WB:WBGene00023053 F47E1.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00023054 F47E1.t3 Is affected by daf-2 based on RNA-seq and microarray studies. WB:WBGene00023055 F47G6.t1 No description available WB:WBGene00023056 F48E3.t1 No description available WB:WBGene00023057 F49D11.t1 No description available WB:WBGene00023058 F49D11.t2 No description available WB:WBGene00023059 F49E7.t1 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00023060 F49E7.t2 Is affected by daf-12 and clk-1 based on tiling array and microarray studies. WB:WBGene00023061 F49E7.t3 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00023062 F52C9.t1 No description available WB:WBGene00023063 F52H2.t1 Is affected by daf-12 and prg-1 based on tiling array and RNA-seq studies. WB:WBGene00023064 F52H2.t2 Is affected by daf-12 based on tiling array studies. WB:WBGene00023065 F53F10.6 Enriched in NSM and intestine based on RNA-seq and microarray studies. Is affected by several genes including daf-12; sir-2.1; and isp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Tunicamycin; and antimycin based on RNA-seq and microarray studies. WB:WBGene00023066 F53F10.7 Enriched in AVK and neurons based on RNA-seq studies. Is affected by several genes including daf-12; cep-1; and dlc-1 based on tiling array and RNA-seq studies. WB:WBGene00023067 rpl-41.1 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. WB:WBGene00023068 rpl-41.2 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. WB:WBGene00023069 rncs-1 Expressed in hypodermal cell and vulva. WB:WBGene00023070 F56C3.t1 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00023071 F56C9.12 Is affected by several genes including daf-12; clk-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00023072 F56F4.t1 No description available WB:WBGene00023073 F56F4.t2 No description available WB:WBGene00023074 F56F10.t1 No description available WB:WBGene00023075 F59C12.t1 No description available WB:WBGene00023076 F59C12.t2 No description available WB:WBGene00023077 F59C12.t3 No description available WB:WBGene00023078 H08J11.t1 No description available WB:WBGene00023079 H08J11.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00023080 H08J11.t3 No description available WB:WBGene00023081 H08J11.t4 No description available WB:WBGene00023082 H08J11.t5 Is affected by daf-2 based on microarray studies. WB:WBGene00023083 H09I01.2 Is affected by hpl-2; clk-1; and daf-2 based on tiling array and microarray studies. WB:WBGene00023084 H19M22.4 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00023085 H35N09.t1 No description available WB:WBGene00023086 H35N09.t2 No description available WB:WBGene00023087 K01A12.t1 Is affected by clk-1 and hmg-3 based on microarray and RNA-seq studies. WB:WBGene00023088 K01A12.t2 No description available WB:WBGene00023089 K01A12.t3 Is affected by clk-1 and hmg-3 based on microarray and RNA-seq studies. WB:WBGene00023090 K01A12.t4 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00023091 K01A12.t5 No description available WB:WBGene00023092 K02D7.t1 No description available WB:WBGene00023093 K03F8.t1 No description available WB:WBGene00023094 K03H6.t1 No description available WB:WBGene00023095 K04A8.t2 No description available WB:WBGene00023096 K04A8.t3 No description available WB:WBGene00023097 K04C2.t1 No description available WB:WBGene00023098 K04C2.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00023099 K04C2.t3 No description available WB:WBGene00023100 K05G3.t1 No description available WB:WBGene00023101 K08B5.t1 No description available WB:WBGene00023102 K08B5.t2 No description available WB:WBGene00023103 K09C6.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00023104 K10F12.8 Is affected by several genes including cyc-1; dlc-1; and pptr-1 based on microarray; tiling array; and RNA-seq studies. Is affected by silicon dioxide nanoparticle; atracurium; and nitroguanidine based on microarray and RNA-seq studies. WB:WBGene00023105 K11C4.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00023106 K11H12.t1 Is affected by daf-12; daf-2; and glp-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00023107 K12H4.t1 No description available WB:WBGene00023108 M01E10.t1 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00023109 M01E10.t2 No description available WB:WBGene00023110 M02F4.t1 No description available WB:WBGene00023111 M02F4.t2 No description available WB:WBGene00023112 M03A1.t1 No description available WB:WBGene00023113 M03A1.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00023115 M57.t1 Is affected by daf-12 based on tiling array studies. WB:WBGene00023116 R02E12.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00023117 R04A9.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00023118 R04E5.t1 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00023119 R04E5.t2 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00023120 R04E5.t3 No description available WB:WBGene00023121 R04E5.t4 No description available WB:WBGene00023122 R04E5.t5 No description available WB:WBGene00023123 R04E5.t6 Is affected by pgrn-1 and rrf-3 based on RNA-seq studies. WB:WBGene00023124 R11B5.t1 No description available WB:WBGene00023125 R11B5.t2 Is affected by clk-1; elli-1; and daf-2 based on microarray studies. WB:WBGene00023126 R11B5.t3 No description available WB:WBGene00023127 R148.t1 No description available WB:WBGene00023128 T03G6.t1 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00023129 T05A8.t1 No description available WB:WBGene00023130 T05A8.t2 No description available WB:WBGene00023131 T05C7.t1 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00023132 T07H6.t1 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00023133 T07H6.t2 No description available WB:WBGene00023134 T08A9.t1 No description available WB:WBGene00023135 T09B4.t1 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00023136 T09B4.t2 Is affected by clk-1 based on microarray studies. WB:WBGene00023137 T13B5.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00023138 T14B4.t1 Enriched in sensory neurons based on RNA-seq studies. Is affected by clk-1; adr-1; and daf-2 based on microarray and RNA-seq studies. WB:WBGene00023139 T14F9.t1 No description available WB:WBGene00023140 T15B12.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00023141 T16D1.t1 No description available WB:WBGene00023142 T20F5.1 Is affected by sir-2.1 based on microarray studies. WB:WBGene00023143 T22F3.t1 No description available WB:WBGene00023144 T22F3.t2 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00023145 T22F3.t3 Is affected by clk-1 based on microarray studies. WB:WBGene00023146 T22F3.t4 No description available WB:WBGene00023147 T22F7.t1 No description available WB:WBGene00023148 T25B6.t1 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00023149 T25B6.t2 No description available WB:WBGene00023150 T25D1.t2 No description available WB:WBGene00023151 T25E4.t1 No description available WB:WBGene00023152 T26C11.t1 No description available WB:WBGene00023153 T27B1.t1 No description available WB:WBGene00023154 T28B4.t1 No description available WB:WBGene00023155 T28C12.t1 No description available WB:WBGene00023156 T28F2.t1 Is affected by clk-1 and pptr-1 based on microarray and RNA-seq studies. WB:WBGene00023157 W02G9.t1 No description available WB:WBGene00023158 W02G9.t2 No description available WB:WBGene00023159 W06H8.5 Enriched in head mesodermal cell; intestine; and neurons based on RNA-seq and microarray studies. Is affected by several genes including dpy-10; sek-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including silicon dioxide nanoparticle; Oligosaccharides; and paraquat based on microarray and RNA-seq studies. WB:WBGene00023160 W09G10.t1 No description available WB:WBGene00023161 W09G10.t2 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00023162 W09G10.t3 Is affected by dlc-1; daf-2; and ints-7 based on RNA-seq and microarray studies. WB:WBGene00023163 W09G12.3 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00023164 W10G11.t1 No description available WB:WBGene00023165 W10G11.t2 No description available WB:WBGene00023166 Y4C6B.t1 No description available WB:WBGene00023167 Y4C6B.t2 No description available WB:WBGene00023168 Y17G9A.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00023169 Y18H1A.t1 Is affected by clk-1; meg-3; and meg-4 based on microarray and RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00023170 Y22D7AL.t3 No description available WB:WBGene00023171 Y22D7AL.t4 No description available WB:WBGene00023172 Y23H5A.8 Enriched in ABplpaapap; ABprpaapap; intestine; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; Alovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00023173 Y25C1A.t1 No description available WB:WBGene00023174 Y25C1A.t2 No description available WB:WBGene00023175 Y37B11A.t2 No description available WB:WBGene00023176 Y39G10AL.t1 No description available WB:WBGene00023177 Y51H7BR.t1 No description available WB:WBGene00023178 Y54G2A.t1 Is affected by prg-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00023179 Y54G2A.t2 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00023180 Y54G2A.t3 Is affected by daf-2 based on microarray studies. WB:WBGene00023181 Y54G2A.t4 Is affected by daf-2 based on microarray studies. WB:WBGene00023182 Y54G2A.t5 Is affected by daf-2 based on microarray studies. WB:WBGene00023183 Y55F3BR.9 Is affected by rsr-2; cep-1; and hmg-3 based on RNA-seq studies. WB:WBGene00023184 Y55F3BR.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00023185 Y59E1B.t2 No description available WB:WBGene00023186 Y67D8B.3 Predicted to be located in membrane. WB:WBGene00023187 Y67D8C.12 Enriched in head mesodermal cell; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; let-418; and dlc-1 based on RNA-seq studies. Is affected by Oligosaccharides and Colistin based on microarray studies. WB:WBGene00023188 Y69A2AR.t2 No description available WB:WBGene00023189 Y71D11A.7 Is affected by clk-1 and daf-2 based on microarray and RNA-seq studies. WB:WBGene00023190 Y71H2AM.t1 No description available WB:WBGene00023191 Y73B3A.17 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; egl-9; and hlh-2 based on RNA-seq and microarray studies. WB:WBGene00023192 Y73B6BL.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00023193 Y74C9A.6 Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies. Is affected by rotenone and atracurium based on RNA-seq studies. WB:WBGene00023194 Y75D11A.t2 Is affected by ced-3 based on RNA-seq studies. WB:WBGene00023195 Y82E9BR.t1 No description available WB:WBGene00023196 Y92C3A.t2 No description available WB:WBGene00023197 Y92C3A.t3 No description available WB:WBGene00023198 Y92H12A.t1 Is affected by atracurium based on RNA-seq studies. WB:WBGene00023199 Y95B8A.t1 No description available WB:WBGene00023200 Y97E10C.t1 Is affected by daf-12; daf-2; and eat-2 based on tiling array and microarray studies. WB:WBGene00023201 Y102E9.t1 No description available WB:WBGene00023202 Y104H12A.t1 No description available WB:WBGene00023203 Y110A2AL.t1 No description available WB:WBGene00023204 Y110A2AL.t2 Is affected by elli-1 and daf-2 based on microarray studies. WB:WBGene00023205 Y119D3B.10 Is affected by nitroguanidine based on microarray studies. WB:WBGene00023206 Y119D3B.t1 No description available WB:WBGene00023207 ZC132.t1 Is affected by prg-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00023208 ZC449.t1 No description available WB:WBGene00023209 ZC513.7 Enriched in coelomocyte; germ line; head mesodermal cell; intestine; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; rrf-3; and gld-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fifteen chemicals including 1-methylnicotinamide; rotenone; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00023210 ZK154.t1 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00023211 ZK154.t2 No description available WB:WBGene00023212 ZK154.t3 Is affected by daf-12 based on tiling array studies. WB:WBGene00023213 ZK154.t4 Is affected by daf-12 based on tiling array studies. WB:WBGene00023214 ZK154.t5 No description available WB:WBGene00023215 ZK380.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00023216 ZK563.t1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00023217 ZK622.t1 No description available WB:WBGene00023218 rte-4 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00023219 ZK783.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00023220 ZK994.t1 No description available WB:WBGene00023221 ZK994.t2 No description available WB:WBGene00023222 ZK994.t3 No description available WB:WBGene00023223 ZK1236.8 Is affected by rnp-6 and etr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00023224 B0280.6 Is affected by daf-16 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00023225 B0281.7 Is affected by several genes including skn-1; elt-2; and clk-1 based on microarray and RNA-seq studies. Is affected by paraquat and bortezomib based on RNA-seq studies. WB:WBGene00023226 B0344.1 Enriched in sensory neurons based on RNA-seq studies. Is affected by kri-1 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00023227 BE0003N10.t1 No description available WB:WBGene00023228 BE0003N10.t2 No description available WB:WBGene00023229 BE0003N10.t3 No description available WB:WBGene00023230 BE0003N10.t4 No description available WB:WBGene00023231 BE0003N10.t5 No description available WB:WBGene00023232 BE0003N10.t6 Is affected by clk-1 based on microarray studies. WB:WBGene00023233 C08A9.2 Is affected by several genes including sir-2.1; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00023234 C09G12.t1 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00023235 C13A2.8 No description available WB:WBGene00023236 C14E2.t1 No description available WB:WBGene00023237 C17C3.14 No description available WB:WBGene00023238 C17H12.7 Is affected by dlc-1; eat-2; and qui-1 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00023239 C18C4.4 Is affected by dlc-1; eat-2; and qui-1 based on RNA-seq studies. Is affected by Rifampin based on RNA-seq studies. WB:WBGene00023240 C23H5.4 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00023241 C23H5.5 Is affected by tatn-1; dlc-1; and adr-2 based on RNA-seq studies. Is affected by metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00023242 C23H5.6 Is affected by eat-2 and adr-2 based on RNA-seq studies. Is affected by allantoin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00023243 C24D10.3 Enriched in intestine based on microarray studies. Is affected by elli-1 based on microarray studies. Is affected by Acrylamide based on microarray studies. WB:WBGene00023244 C24H12.3 Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00023245 C33E10.3 Enriched in germ line and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00023246 C33E10.4 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and pgl-1 based on RNA-seq studies. Is affected by nitroguanidine based on microarray studies. WB:WBGene00023247 C33E10.7 Is affected by several genes including daf-2; eat-2; and let-418 based on RNA-seq and microarray studies. Is affected by metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00023248 C33E10.9 Is affected by clk-1; adr-1; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00023249 C35B1.t1 No description available WB:WBGene00023250 C36C9.t1 No description available WB:WBGene00023251 C36C9.t3 No description available WB:WBGene00023252 C39H7.2 Enriched in LUA and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on RNA-seq studies. Is affected by nine chemicals including stavudine; Zidovudine; and metformin based on RNA-seq studies. WB:WBGene00023253 C44C11.t1 No description available WB:WBGene00023254 C44C11.t2 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00023255 C45H4.t1 No description available WB:WBGene00023256 C50A2.t1 No description available WB:WBGene00023257 C50A2.t2 No description available WB:WBGene00023259 C52D10.10 Is affected by several genes including daf-16; dpy-10; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Quercetin; and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00023260 C52E12.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00023262 C54F6.2 Is affected by daf-16; eat-2; and sams-3 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00023263 D1005.t1 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; sek-1; and tph-1 based on RNA-seq studies. Is affected by Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00023264 D1065.2 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by Alovudine and stavudine based on RNA-seq studies. WB:WBGene00023265 E03H12.8 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00023266 F07E5.10 Is affected by several genes including skn-1; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by bortezomib based on RNA-seq studies. WB:WBGene00023267 F07G11.6 Is affected by several genes including eat-2; clk-1; and prg-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00023268 F15A8.3 No description available WB:WBGene00023269 F16F9.t1 No description available WB:WBGene00023270 F17E9.14 Enriched in sensory neurons based on RNA-seq studies. Is affected by smg-2 and etr-1 based on RNA-seq studies. WB:WBGene00023271 F19G12.t1 Is affected by several genes including eat-2; hpl-2; and mir-71 based on RNA-seq studies. Is affected by eight chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00023272 F22E5.19 No description available WB:WBGene00023273 F23C8.2 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00023274 F23C8.10 Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00023275 F23G4.t1 Is affected by prx-5 based on RNA-seq studies. WB:WBGene00023276 F25B4.3 Is affected by prg-1 and hlh-26 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00023277 F29C4.3 Is affected by several genes including clk-1; dpy-7; and smn-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00023278 F30D4.1 Is affected by clk-1 based on microarray studies. WB:WBGene00023279 F36A4.9 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00023281 F39E9.8 Is affected by clk-1; etr-1; and lpd-3 based on microarray and RNA-seq studies. WB:WBGene00023282 F39E9.9 Enriched in PQR based on single-cell RNA-seq studies. WB:WBGene00023283 F40H7.6 No description available WB:WBGene00023284 F41B5.1 Predicted to enable DNA binding activity and metal ion binding activity. WB:WBGene00023285 F42G2.t1 No description available WB:WBGene00023286 F44C4.6 No description available WB:WBGene00023287 F46F5.3 No description available WB:WBGene00023288 F49F1.13 Is affected by eat-2; meg-3; and meg-4 based on RNA-seq studies. WB:WBGene00023289 F53A3.5 Is affected by daf-2; rnp-6; and mrps-5 based on microarray and RNA-seq studies. WB:WBGene00023290 F53B1.t1 No description available WB:WBGene00023291 F53H1.2 Is affected by smg-2 and etr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00023292 F54D8.9 No description available WB:WBGene00023293 F54D12.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00023294 F54D12.t2 Is affected by clk-1 based on microarray studies. WB:WBGene00023295 F56C11.t1 Is affected by eat-2 and mrps-5 based on RNA-seq studies. WB:WBGene00023296 F56D12.t1 No description available WB:WBGene00023297 F56D12.t2 No description available WB:WBGene00023298 F56D12.t3 No description available WB:WBGene00023299 F56D12.t4 Is affected by clk-1 based on microarray studies. WB:WBGene00023300 F56F11.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00023301 F58E2.1 Enriched in muscle cell and neurons based on microarray studies. Is affected by several genes including sir-2.1; clk-1; and fbf-1 based on microarray and RNA-seq studies. Is affected by triclosan based on microarray studies. WB:WBGene00023302 F58E2.6 Enriched in neurons based on microarray studies. Is affected by clk-1; etr-1; and hlh-26 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00023303 F58E2.8 Is affected by eat-2 based on RNA-seq studies. Is affected by Rifampin based on RNA-seq studies. WB:WBGene00023304 F58F6.t1 Is affected by clk-1 and mrps-5 based on microarray and RNA-seq studies. WB:WBGene00023305 F58F6.t2 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00023306 F59A7.10 Is affected by several genes including daf-2; eat-2; and etr-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube and Colistin based on RNA-seq and microarray studies. WB:WBGene00023307 H06I04.t1 No description available WB:WBGene00023308 H11E01.t1 Is affected by several genes including daf-2; eat-2; and hpl-2 based on RNA-seq and microarray studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00023309 H17B01.t1 No description available WB:WBGene00023310 H17B01.t2 No description available WB:WBGene00023311 H17B01.t3 No description available WB:WBGene00023312 H17B01.t4 No description available WB:WBGene00023313 H28G03.5 Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00023314 H31G24.2 Enriched in body wall musculature and sensory neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; ain-1; and ain-2 based on RNA-seq and microarray studies. Is affected by Rifampin; allantoin; and Psoralens based on RNA-seq studies. WB:WBGene00023315 K02E7.8 Is affected by adr-1 and eat-2 based on RNA-seq studies. Is affected by Sirolimus based on RNA-seq studies. WB:WBGene00023316 K02E7.t1 No description available WB:WBGene00023317 K02H11.8 No description available WB:WBGene00023318 K07D4.1 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including stavudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00023319 K07E8.2 Is affected by clk-1; etr-1; and sir-2.1 based on microarray and RNA-seq studies. WB:WBGene00023320 K07E8.4 Enriched in intestine based on microarray studies. Is affected by several genes including eat-2; met-2; and set-25 based on RNA-seq studies. Is affected by four chemicals including Rifampin; Psoralens; and Cholestanol based on RNA-seq and microarray studies. WB:WBGene00023321 K07E8.8 Is affected by clk-1 and sir-2.1 based on microarray studies. WB:WBGene00023322 K08B12.4 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; let-418; and chd-3 based on RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00023323 K08F11.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by paraquat and Hydrolyzable Tannins based on RNA-seq and microarray studies. WB:WBGene00023324 K10B2.t1 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00023325 K10F12.1 Is affected by hmg-3 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00023326 M03D4.5 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00023327 R03H4.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00023328 R04B3.t1 No description available WB:WBGene00023329 R04B3.t2 No description available WB:WBGene00023330 R13D7.5 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00023331 R13H7.3 Is affected by qui-1 based on RNA-seq studies. WB:WBGene00023332 R148.t2 No description available WB:WBGene00023333 R148.t3 No description available WB:WBGene00023334 R148.t4 No description available WB:WBGene00023335 T03D3.7 Is affected by sir-2.1 based on microarray studies. WB:WBGene00023336 T03D3.8 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by clk-1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00023337 T03D3.9 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00023338 T03D3.10 Is affected by lpd-3 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00023339 T03D3.13 Is affected by sir-2.1 based on microarray studies. WB:WBGene00023340 T05B11.5 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00023341 T05H4.t1 No description available WB:WBGene00023342 T05H4.t2 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00023343 T06A1.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by daf-16 based on RNA-seq studies. WB:WBGene00023344 T08B2.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00023345 T12B5.9 Is affected by several genes including mir-71; smg-2; and mrps-5 based on RNA-seq studies. Is affected by Sodium Chloride and Ketamine based on RNA-seq studies. WB:WBGene00023346 T13B5.t1 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00023347 T22F3.1 No description available WB:WBGene00023348 T24E12.7 Is affected by eat-2 based on RNA-seq studies. Is affected by metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00023349 T25D1.t1 Is affected by dpy-21 and eat-2 based on RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00023351 T27C4.5 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00023352 T28B4.t2 No description available WB:WBGene00023353 W01H2.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00023354 W02D7.1 Is affected by flcn-1 based on microarray studies. WB:WBGene00023355 W02F12.1 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and unc-30 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00023356 W03F9.8 No description available WB:WBGene00023357 W03H1.t1 No description available WB:WBGene00023358 W10G11.8 Is affected by several genes including eat-2; clk-1; and rrf-1 based on microarray and RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00023359 Y4C6B.t3 No description available WB:WBGene00023360 Y22D7AL.t1 No description available WB:WBGene00023361 Y22D7AL.t2 No description available WB:WBGene00023362 Y22D7AL.t5 Is affected by clk-1 based on microarray studies. WB:WBGene00023363 Y22D7AL.t6 Is affected by clk-1 based on microarray studies. WB:WBGene00023364 Y22D7AR.t1 No description available WB:WBGene00023365 Y34B4A.t1 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00023366 Y37E11B.t1 No description available WB:WBGene00023367 Y37E11B.t2 No description available WB:WBGene00023368 Y37F4.t1 No description available WB:WBGene00023369 Y37F4.t2 No description available WB:WBGene00023370 Y39A3B.t1 Is affected by daf-2 based on microarray studies. WB:WBGene00023371 Y47C4A.t1 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00023372 Y47C4A.t2 Is affected by eat-2 based on RNA-seq studies. WB:WBGene00023373 Y53G8B.t1 No description available WB:WBGene00023375 Y53G8B.t3 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00023376 Y53G8B.t4 Is affected by clk-1 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00023377 Y53G8B.t5 No description available WB:WBGene00023378 Y53G8B.t6 No description available WB:WBGene00023379 Y53G8B.t7 No description available WB:WBGene00023380 Y53G8B.t8 No description available WB:WBGene00023381 Y53G8B.t9 No description available WB:WBGene00023382 Y57E12AL.3 Is affected by several genes including daf-16; daf-12; and hsf-1 based on microarray and RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00023383 Y59E1B.t1 No description available WB:WBGene00023384 Y60C6A.t1 No description available WB:WBGene00023385 Y67D2.t1 Is affected by clk-1 based on microarray studies. WB:WBGene00023386 Y67D2.t2 No description available WB:WBGene00023387 Y67D2.t3 No description available WB:WBGene00023388 Y67D2.t4 Is affected by clk-1 based on microarray studies. WB:WBGene00023389 Y69A2AR.t1 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00023390 Y69A2AR.t3 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00023391 Y73B3A.t1 Is affected by smg-2; ins-11; and xpf-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00023392 Y77E11A.t1 Is affected by clk-1 and eat-2 based on microarray studies. WB:WBGene00023393 Y77E11A.t2 Is affected by clk-1 based on microarray studies. WB:WBGene00023394 Y77E11A.t3 No description available WB:WBGene00023395 Y82E9BL.9 Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00023396 Y94H6A.t1 Is affected by dpy-21 and eat-2 based on RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00023397 Y104H12A.t2 Is affected by smn-1 based on RNA-seq studies. WB:WBGene00023398 ZC123.t1 No description available WB:WBGene00023399 ZC239.1 Is affected by several genes including eat-2; clk-1; and mut-16 based on RNA-seq and microarray studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00023400 ZK380.3 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00023401 ZK380.t2 Enriched in I4 neuron and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and rrf-3 based on RNA-seq studies. Is affected by eleven chemicals including rotenone; manganese chloride; and multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00023402 ZK488.3 Is affected by Colistin based on microarray studies. WB:WBGene00023403 ZK682.1 No description available WB:WBGene00023404 plr-1 Predicted to enable ubiquitin-protein transferase activity. Involved in negative regulation of Wnt signaling pathway. Located in Golgi apparatus; early endosome; and late endosome. Expressed in several structures, including egg-laying apparatus; enteric muscle; neurons; pharynx; and tail. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); irritable bowel syndrome; and villous adenoma. Is an ortholog of human RNF43 (ring finger protein 43) and ZNRF3 (zinc and ring finger 3). WB:WBGene00023405 sor-1 Enables RNA binding activity. Involved in epigenetic regulation of gene expression. Located in nuclear speck. WB:WBGene00023406 K01G12.1 No description available WB:WBGene00023407 cex-1 Predicted to enable metal ion binding activity. Expressed in RIML and RIMR. WB:WBGene00023408 cex-2 Predicted to enable metal ion binding activity. Expressed in head and tail. WB:WBGene00023409 mbd-2 Predicted to enable methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent heterochromatin formation and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in rheumatoid arthritis and schizophrenia. Is an ortholog of human MBD2 (methyl-CpG binding domain protein 2). WB:WBGene00023410 clpr-2 Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00023411 srz-3 Predicted to be located in membrane. WB:WBGene00023413 H31B20.2 Enriched in dopaminergic neurons and neurons based on tiling array and RNA-seq studies. Is affected by rsr-2 based on tiling array studies. WB:WBGene00023414 R01H2.7 Predicted to be located in membrane. WB:WBGene00023415 F16C3.3 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00023416 spi-1 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00023417 swm-1 Predicted to enable serine-type endopeptidase inhibitor activity. Involved in spermatid development. Located in extracellular space and secretory vesicle. Expressed in body wall musculature; coelomocyte; reproductive tract; and in male. WB:WBGene00023418 R06F6.12 Enriched in germ line and hypodermis based on RNA-seq studies. Is affected by several genes including dpy-10; sek-1; and pgl-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00023419 F53F4.16 Enriched in several structures, including body wall muscle cell; germ line; intestine; marginal cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; let-7; and gld-1 based on RNA-seq; microarray; and proteomic studies. Is affected by seven chemicals including hydrogen sulfide; rotenone; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00023420 C26D10.7 Predicted to enable kinase activity. Predicted to be involved in syncytium formation by plasma membrane fusion. Predicted to be located in cell-cell contact zone. WB:WBGene00023421 rde-11 Predicted to enable metal ion binding activity. Predicted to be involved in regulation of translation and regulatory ncRNA-mediated gene silencing. WB:WBGene00023422 mrpl-21 Predicted to be a structural constituent of ribosome. Predicted to be located in cytoplasm and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPL21 (mitochondrial ribosomal protein L21). WB:WBGene00023423 F43C1.7 Predicted to be located in endomembrane system. Is an ortholog of human CCDC25 (coiled-coil domain containing 25). WB:WBGene00023424 C53D6.10 Predicted to be located in membrane. WB:WBGene00023425 try-9 Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. WB:WBGene00023427 F14D2.15 Enriched in AFD; ALN; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Zidovudine; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00023428 K07C5.10 Is affected by several genes including clk-1; pgl-1; and cep-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00023429 W08G11.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including hpl-2; set-2; and lin-52 based on microarray and RNA-seq studies. WB:WBGene00023430 D1054.17 Enriched in AFD based on RNA-seq studies. Is affected by several genes including cep-1; dpy-21; and set-2 based on RNA-seq studies. WB:WBGene00023431 C25E10.13 Enriched in AMshL; AMshR; OLL; PVD; and amphid sheath cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including aak-2; unc-30; and set-2 based on RNA-seq studies. Is affected by antimycin and cholesterol based on RNA-seq studies. WB:WBGene00023432 K12B6.9 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including elt-2; pgl-1; and aak-2 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including rotenone; mianserin; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00023433 B0513.10 No description available WB:WBGene00023434 C04F12.11 No description available WB:WBGene00023435 C31A11.8 No description available WB:WBGene00023436 F08G12.6 No description available WB:WBGene00023437 F35E8.3 No description available WB:WBGene00023438 F59C6.1 No description available WB:WBGene00023439 R05A10.9 No description available WB:WBGene00023440 T01C1.1 No description available WB:WBGene00023441 T21B4.11 No description available WB:WBGene00023442 Y37D8A.7 No description available WB:WBGene00023443 Y51A2C.1 No description available WB:WBGene00023444 Y51H4A.29 No description available WB:WBGene00023445 Y73F8A.28 No description available WB:WBGene00023446 Y94A7B.2 No description available WB:WBGene00023447 ZC334.4 No description available WB:WBGene00023448 ZK856.2 No description available WB:WBGene00023449 ZK1251.4 No description available WB:WBGene00023450 T12D8.10 Predicted to enable iron-sulfur cluster binding activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to be located in cytosol and nucleus. Is an ortholog of human BOLA2 (bolA family member 2) and BOLA2B (bolA family member 2B). WB:WBGene00023451 mlc-7 Predicted to enable calcium ion binding activity. Predicted to be part of myosin II complex. Human ortholog(s) of this gene implicated in congenital myopathy 14; familial atrial fibrillation; and hypertrophic cardiomyopathy 8. Is an ortholog of several human genes including MYL1 (myosin light chain 1); MYL3 (myosin light chain 3); and MYL4 (myosin light chain 4). WB:WBGene00023452 mir-353 Is affected by several genes including daf-12; prg-1; and alg-1 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube and nicotine based on RNA-seq studies. WB:WBGene00023453 mir-356.1 Is affected by several genes including pptr-1; tdp-1; and etr-1 based on RNA-seq studies. WB:WBGene00023454 mir-357 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. WB:WBGene00023455 mir-358 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by nicotine and silicon dioxide nanoparticle based on quantitative PCR and microarray studies. WB:WBGene00023456 mir-360 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and graphene oxide based on RNA-seq studies. WB:WBGene00023457 mir-359 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. WB:WBGene00023458 M02E1.3 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-16; sek-1; and smg-1 based on RNA-seq studies. Is affected by mianserin; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00023459 Y18D10A.26 Is affected by several genes including eat-2; prg-1; and dpy-21 based on tiling array and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00023460 F46H6.5 Enriched in ADE sheath cell; AFD; AVH; excretory cell; and muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and elt-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00023461 F53G12.12 Is affected by daf-12; cep-1; and dpy-21 based on tiling array and RNA-seq studies. WB:WBGene00023462 srz-83 Predicted to be located in membrane. WB:WBGene00023463 srz-82 Predicted to be located in membrane. WB:WBGene00023464 srz-80 Is affected by eat-2 based on RNA-seq studies. Is affected by Rifampin and Sirolimus based on RNA-seq studies. WB:WBGene00023465 srz-81 Is affected by several genes including alg-1; qui-1; and adr-1 based on RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00023466 R151.11 Enriched in AFD based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00023467 Y38F2AR.14 Enriched in AFD based on RNA-seq studies. Is affected by several genes including prg-1; hpl-2; and set-2 based on RNA-seq studies. WB:WBGene00023468 B0412.6 Enriched in AFD based on RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00023469 C16A3.11 Enriched in AVK based on RNA-seq studies. Is affected by several genes including daf-12; pgl-1; and prg-1 based on tiling array and RNA-seq studies. Is affected by rotenone based on RNA-seq studies. WB:WBGene00023470 srz-87 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. Is affected by metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00023471 srz-86 Is affected by several genes including clk-1; pgl-1; and glh-1 based on microarray and RNA-seq studies. WB:WBGene00023472 F16A11.5 Enriched in head mesodermal cell; muscle cell; and sensory neurons based on RNA-seq and microarray studies. Is affected by several genes including cep-1; alg-1; and let-418 based on RNA-seq studies. Is affected by multi-walled carbon nanotube; metformin; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00023473 F58A4.13 No description available WB:WBGene00023474 srz-37 Predicted to be located in membrane. WB:WBGene00023475 srz-69 Predicted to be located in membrane. WB:WBGene00023476 srz-55 Enriched in neurons based on microarray studies. Is affected by etr-1 and ain-2 based on RNA-seq and microarray studies. WB:WBGene00023477 nspc-1 Enriched in excretory gland cell and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including Ethanol; rotenone; and mianserin based on RNA-seq and microarray studies. WB:WBGene00023478 srz-62 Predicted to be located in membrane. WB:WBGene00023479 srz-67 Predicted to be located in membrane. WB:WBGene00023480 srz-68 Enriched in ADL based on single-cell RNA-seq studies. Is affected by etr-1 and lin-52 based on RNA-seq studies. WB:WBGene00023481 srz-22 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00023482 C05B5.9 Is affected by several genes including hsf-1; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00023483 Y75B8A.39 Enriched in XXX cell; intestine; neurons; and retrovesicular ganglion based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seventeen chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00023484 Y54G2A.37 Enriched in RIS; germline precursor cell; hypodermis; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and elt-2 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including methylmercury hydroxide; mianserin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00023485 ttr-49 Predicted to be located in cell surface and extracellular region. WB:WBGene00023486 K08B4.7 Enriched in F cell; U cell; coelomocyte; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including rotenone; Tunicamycin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00023487 mrps-24 Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial small ribosomal subunit. Is an ortholog of human MRPS24 (mitochondrial ribosomal protein S24). WB:WBGene00023488 srz-84 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00023489 F42A10.9 Predicted to enable gamma-glutamylaminecyclotransferase activity. Predicted to be located in cytosol. Is an ortholog of human GGACT (gamma-glutamylamine cyclotransferase). WB:WBGene00023490 F36A2.14 Enriched in arcade cell; germ line; pharyngeal-intestinal valve cell; and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty chemicals including nicotinic acid; Tunicamycin; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00023491 tsp-21 Enables identical protein binding activity. Involved in positive regulation of signal transduction; regulation of growth; and regulation of mesodermal cell fate specification. Located in basolateral plasma membrane. Expressed in several structures, including M lineage cell; gonad; intestine; rectal epithelium; and vulva. Used to study cancer. Human ortholog(s) of this gene implicated in exudative vitreoretinopathy 5. Is an ortholog of human CD53 (CD53 molecule) and TSPAN12 (tetraspanin 12). WB:WBGene00023492 T24D3.2 Enriched in PLM; dopaminergic neurons; hypodermis; and pharyngeal muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Ethanol; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00023493 nspc-12 Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by six chemicals including hydrogen sulfide; mianserin; and metformin based on microarray and RNA-seq studies. WB:WBGene00023494 osr-2 No description available WB:WBGene00023495 osr-3 No description available WB:WBGene00023496 osr-4 No description available WB:WBGene00023497 lin-15B Predicted to enable DNA binding activity and metal ion binding activity. Involved in negative regulation of Ras protein signal transduction; negative regulation of vulval development; and regulation of cell fate specification. Expressed in several structures, including anterior gonad arm; oocyte; and somatic cell. WB:WBGene00023498 lin-15A Involved in several processes, including negative regulation of vulval development; protein stabilization; and vulval development. Located in nucleus. Expressed in gonad. WB:WBGene00023499 srz-63 Predicted to be located in membrane. WB:WBGene00023500 C11H1.9 Enriched in several structures, including ADE sheath cell; G2; W cell; anterior ganglion; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on proteomic; microarray; and RNA-seq studies. Is affected by eleven chemicals including D-glucopyranose; levamisole; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: CRAL-TRIO lipid binding domain; GOLD domain superfamily; CRAL-TRIO lipid binding domain superfamily; and CRAL/TRIO domain. WB:WBGene00023501 F11E6.11 Predicted to be located in membrane. WB:WBGene00023502 clec-184 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. WB:WBGene00023503 F17C11.13 Predicted to be located in membrane. WB:WBGene00023504 F26F2.8 Enriched in several structures, including ABaraapapaa; ABaraapppaa; MSaapaapa; excretory gland cell; and pharyngeal cell based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by nine chemicals including hydrogen sulfide; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Caenorhabditis elegans ly-6-related. WB:WBGene00023505 srz-102 Predicted to be located in membrane. Expressed in ADLL; ADLR; PVT; and vulva. WB:WBGene00023506 srz-11 Predicted to be located in membrane. WB:WBGene00023507 srz-26 No description available WB:WBGene00023508 srz-38 Predicted to be located in membrane. WB:WBGene00023509 srz-39 No description available WB:WBGene00023510 srz-40 No description available WB:WBGene00023511 srz-41 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00023512 srz-51 Is affected by clk-1 and daf-2 based on microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00023513 srz-71 Predicted to be located in membrane. WB:WBGene00023514 srz-72 Predicted to be located in membrane. WB:WBGene00023515 srz-97 Predicted to be located in membrane. WB:WBGene00023516 srz-98 No description available WB:WBGene00023517 srz-75 Predicted to be located in membrane. WB:WBGene00023518 srz-76 Enriched in NSM and neurons based on tiling array and RNA-seq studies. Is affected by several genes including let-60; clk-1; and drh-3 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00023519 Y60A3A.24 Enriched in AIZL; AIZR; AVJL; and AVJR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; stavudine; and bortezomib based on RNA-seq studies. WB:WBGene00023520 oig-5 Enriched in interneuron; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; aak-2; and unc-30 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Immunoglobulin I-set; Immunoglobulin-like domain superfamily; Immunoglobulin-like fold; and Immunoglobulin I-set domain. WB:WBGene00043049 F32H2.11 Enriched in Z1.p; Z4.a; male distal tip cell; seam cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Ethanol; methylmercury hydroxide; and stearic acid based on RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function, DUF273; Protein of unknown function DUF273; and Nucleotide-diphospho-sugar transferases. WB:WBGene00043050 oig-4 Located in extracellular space and neuromuscular junction. Expressed in body wall musculature; neurons; pm6; and somatic nervous system. WB:WBGene00043051 C29E4.13 Enriched in AVA; germ line; and germline precursor cell based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and unc-30 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00043052 srz-104 Predicted to be located in membrane. Expressed in ADLL; ADLR; and PVT. WB:WBGene00043053 F47H4.12 Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00043054 T21B4.15 Enriched in several structures, including RIB; Y cell; head mesodermal cell; sensory neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and unc-30 based on RNA-seq and microarray studies. Is affected by six chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00043055 F19B2.10 Enriched in AVK based on RNA-seq studies. Is affected by clk-1; eat-2; and daf-2 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00043056 nfya-2 Enables DNA-binding transcription repressor activity. Involved in regulation of gene expression and tissue development. Located in nucleus. Expressed in excretory cell; gonad; head neurons; intestine; and oocyte. Is an ortholog of human NFYA (nuclear transcription factor Y subunit alpha). WB:WBGene00043057 M142.8 Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in macromolecule methylation; nitrogen compound metabolic process; and primary metabolic process. Predicted to be located in cytoplasm. Is an ortholog of human EEF1AKMT1 (EEF1A lysine methyltransferase 1). WB:WBGene00043058 sre-34 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00043059 srab-26 Predicted to be located in membrane. WB:WBGene00043060 R144.12 Enriched in body wall muscle cell and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; microarray; and RNA-seq studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Transmembrane protein 177. Is an ortholog of human TMEM177 (transmembrane protein 177). WB:WBGene00043061 Y54G2A.38 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00043062 clec-80 Enriched in ASER; SIA; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including methylmercuric chloride; rotenone; and mianserin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00043064 nbet-1 Predicted to enable SNAP receptor activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and vesicle fusion with Golgi apparatus. Predicted to be located in Golgi apparatus and membrane. Predicted to be part of SNARE complex. Is an ortholog of human BET1 (Bet1 golgi vesicular membrane trafficking protein). WB:WBGene00043065 C55C3.7 Enriched in AVA and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; glp-1; and pie-1 based on tiling array; RNA-seq; and microarray studies. Is affected by sodium arsenite; atracurium; and nitroguanidine based on RNA-seq and microarray studies. WB:WBGene00043066 acr-25 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). WB:WBGene00043067 dlc-5 Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based process. Predicted to be located in cellular anatomical entity. Predicted to be part of cytoplasmic dynein complex. Expressed in pharynx. WB:WBGene00043068 F32E10.9 Enriched in several structures, including ABalpppappp; ABarpapaaa; AVK; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by four chemicals including rotenone; manganese chloride; and antimycin based on RNA-seq studies. WB:WBGene00043069 F20D6.12 Predicted to be located in membrane. WB:WBGene00043097 C02D5.4 Predicted to enable glutathione dehydrogenase (ascorbate) activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Is an ortholog of human GSTO1 (glutathione S-transferase omega 1) and GSTO2 (glutathione S-transferase omega 2). WB:WBGene00043120 C09H10.4 Predicted to be located in membrane. WB:WBGene00043147 nspd-6 Enriched in amphid sheath cell; germ line; intestine; sperm; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-four chemicals including Ethanol; methylmercury hydroxide; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Caenorhabditis elegans protein of unknown function (DUF780) and Protein of unknown function DUF780, Caenorhabditis species. WB:WBGene00043156 C27F2.9 Predicted to be located in cytoplasm. Is an ortholog of human JMJD8 (jumonji domain containing 8). WB:WBGene00043187 nspa-9 Enriched in neurons based on microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on quantitative PCR; microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including hydrogen sulfide; resveratrol; and Acrylamide based on microarray and RNA-seq studies. WB:WBGene00043239 F08D12.5 Is affected by bcat-1; sir-2.1; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00043279 F22D6.8 Predicted to be located in ribosome. WB:WBGene00043283 F23B2.9 Enriched in AVK based on RNA-seq studies. Is affected by clk-1 based on microarray studies. Is affected by Progesterone and resveratrol based on microarray studies. WB:WBGene00043297 F28F5.4 Enriched in several structures, including MSaapaapa; coelomocyte; neurons; pharyngeal cell; and rectal gland cell based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and aak-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including multi-walled carbon nanotube; Sodium Chloride; and metformin based on RNA-seq and microarray studies. WB:WBGene00043302 F32D8.11 Enriched in intestine; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; clk-1; and aak-2 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including D-glucopyranose; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00043308 tmem-107 Involved in dendrite development; non-motile cilium assembly; and protein localization to ciliary transition zone. Located in ciliary transition zone. Expressed in ciliated neurons. WB:WBGene00043327 F45D11.7 Is affected by bet-1 and mys-1 based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00043328 F45D11.11 Is affected by eri-1 and mut-2 based on microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00043408 K03H6.3 No description available WB:WBGene00043419 K08A2.6 No description available WB:WBGene00043466 R05G6.3 Enriched in MSaapaapa; MSpapaapa; XXX cell; and g1 based on single-cell RNA-seq studies. Is affected by eat-2; csr-1; and mir-243 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00043469 R09H3.2 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by several genes including eat-2; hda-1; and mep-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00043534 W02B12.13 Enriched in neurons and retrovesicular ganglion based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including rotenone; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00043537 W03G1.3 No description available WB:WBGene00043538 W03G1.4 No description available WB:WBGene00043666 Y45G5AM.4 Enriched in several structures, including ABplaapapa; ABpraapapa; PLM; carbon dioxide sensory neurons; and pharyngeal-intestinal valve cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and dpy-21 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00043702 Y54G2A.7 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and elt-2 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00043705 egrh-2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); lung disease (multiple); and neuropathy (multiple). Is an ortholog of human EGR1 (early growth response 1) and EGR3 (early growth response 3). WB:WBGene00043707 Y55F3C.6 No description available WB:WBGene00043743 nsph-4.1 Enriched in several structures, including I5 neuron; MSaapaapa; MSpapaapa; cholinergic neurons; and sperm based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on proteomic; RNA-seq; and microarray studies. Is affected by twenty-four chemicals including Ethanol; methylmercury hydroxide; and D-glucose based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Cytosolic motility protein. WB:WBGene00043948 ZC262.7 Enriched in F cell and U cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and alg-1 based on RNA-seq; proteomic; and microarray studies. Is affected by six chemicals including nicotine; Sodium Chloride; and Psoralens based on proteomic and RNA-seq studies. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 3; asbestos-related lung carcinoma; autoimmune disease (multiple); and complex cortical dysplasia with other brain malformations 2. Human KIF5B enables identical protein binding activity; microtubule binding activity; and microtubule motor activity. Is an ortholog of human KIF5A (kinesin family member 5A); KIF5B (kinesin family member 5B); and KIF5C (kinesin family member 5C). WB:WBGene00043952 ZC404.2 Predicted to be located in membrane. WB:WBGene00043980 F11D5.7 Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be located in membrane. WB:WBGene00043981 aaim-1 Involved in regulation of entry of bacterium into host cell. Located in extracellular space. WB:WBGene00043982 B0403.6 Predicted to be located in membrane. WB:WBGene00043983 C39D10.11 Enriched in head mesodermal cell; intestine; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Tunicamycin; D-glucopyranose; and stavudine based on microarray and RNA-seq studies. WB:WBGene00043984 C56E6.7 Enriched in ADE sheath cell; IL socket cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including clk-1; set-2; and mir-34 based on microarray and RNA-seq studies. WB:WBGene00043985 C44C10.11 Enriched in several structures, including ABplppppap; ABprppppap; head mesodermal cell; intestine; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including D-glucose; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00043986 fut-5 Enables 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity. Involved in fucosylation. Predicted to be located in Golgi cisterna membrane. Is an ortholog of human FUT7 (fucosyltransferase 7). WB:WBGene00043987 AC8.9 Is affected by several genes including daf-16; hsf-1; and sek-1 based on RNA-seq and microarray studies. Is affected by Chlorpyrifos and Diazinon based on microarray studies. WB:WBGene00043988 AC8.10 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00043989 AC8.11 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on RNA-seq and proteomic studies. Is affected by five chemicals including metformin; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00043990 AC8.12 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00043991 mir-258.2 Is affected by multi-walled carbon nanotube and Ketamine based on RNA-seq studies. WB:WBGene00043992 bbs-4 Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in centrosome cycle; cilium assembly; and protein localization to cilium. Located in ciliary basal body. Used to study Bardet-Biedl syndrome. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 4 and morbid obesity. Is an ortholog of human BBS4 (Bardet-Biedl syndrome 4). WB:WBGene00043993 T26G10.6 Is affected by daf-16; dpy-21; and eat-2 based on RNA-seq studies. WB:WBGene00043994 C07A9.12 Predicted to be located in membrane. WB:WBGene00043995 F40F12.9 Predicted to enable mRNA binding activity; single-stranded RNA binding activity; and translation regulator activity. Predicted to be involved in positive regulation of cytoplasmic translation. Predicted to be located in cytoplasm. WB:WBGene00043996 fbxb-87 Enriched in ABalapppaa; AVA; anterior hypodermis; and intestine based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00043997 Y79H2A.12 Predicted to be located in membrane. WB:WBGene00043998 T21C12.8 Predicted to be located in membrane. WB:WBGene00044000 Y75B8A.41 Is affected by several genes including daf-16; eat-2; and cat-2 based on RNA-seq studies. WB:WBGene00044001 C09G4.4 Enriched in several structures, including ABalaapppa; ABalapaapa; GLR; ciliated neurons; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044002 srt-74 Predicted to be located in membrane. WB:WBGene00044003 Y41E3.18 Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to be located in endosome membrane and plasma membrane. WB:WBGene00044004 C24A8.6 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00044005 F37C12.18 Enriched in amphid sheath cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fourteen chemicals including nicotinic acid; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00044006 nlp-82 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00044007 ZK1320.13 Enriched in intestine; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including rotenone; stavudine; and Psoralens based on RNA-seq studies. WB:WBGene00044008 gip-2 Predicted to be located in adherens junction; hemidesmosome; and microtubule. Expressed in nervous system. WB:WBGene00044009 srlf-33 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00044011 idpc-3 Enriched in arc ant V; arcade cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by sixteen chemicals including Ethanol; tryptophan; and methylmercury hydroxide based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Pistil-specific extensin-like protein. WB:WBGene00044012 srxa-19 Predicted to be located in membrane. WB:WBGene00044013 F15H10.9 Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including lin-35; lin-15B; and met-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00044014 F15H10.10 Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including eat-2; sir-2.1; and lin-35 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00044015 K06A4.8 Is affected by several genes including daf-2; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including manganese chloride; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044016 C35A5.10 Enriched in pharyngeal-intestinal valve based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including 1-methylnicotinamide; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cysteine-rich repeat. WB:WBGene00044018 T04B2.8 Predicted to be located in membrane. WB:WBGene00044019 C55A6.12 Enriched in several structures, including CAN; germline precursor cell; intestine; somatic gonad precursor; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by eighteen chemicals including rotenone; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Calycin. WB:WBGene00044020 ZK856.14 Predicted to be located in membrane. Expressed in ASEL; ASER; and neurons. WB:WBGene00044021 R02E4.2 Predicted to be located in membrane. WB:WBGene00044022 AC3.9 Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00044024 C35A5.11 Enriched in germline precursor cell; hypodermis; intestine; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00044025 T01G1.4 Predicted to enable dehydrodolichyl diphosphate synthase activity and polyprenyltransferase activity. Predicted to be involved in polyprenol biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be part of dehydrodolichyl diphosphate synthase complex. Human ortholog(s) of this gene implicated in developmental delay and seizures with or without movement abnormalities and retinitis pigmentosa 59. Is an ortholog of human DHDDS (dehydrodolichyl diphosphate synthase subunit). WB:WBGene00044026 cisd-1 Predicted to enable 2 iron, 2 sulfur cluster binding activity. Predicted to be involved in regulation of autophagy. Predicted to be located in mitochondrial outer membrane. Expressed in embryonic cell and intestinal cell. Human ortholog(s) of this gene implicated in Wolfram syndrome 2. Is an ortholog of human CISD1 (CDGSH iron sulfur domain 1). WB:WBGene00044027 F27E5.8 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00044028 nlp-63 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00044029 C05D12.7 Enriched in ABaraappaa; GLR; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; eat-2; and elt-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044030 Y17G7B.23 Enriched in ABplpapppa; ABprpapppa; posterior arcade cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including mianserin; multi-walled carbon nanotube; and Zidovudine based on RNA-seq studies. WB:WBGene00044031 F49C5.9 Predicted to be located in membrane. WB:WBGene00044032 ceh-99 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in brain development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00044034 Y38E10A.28 Predicted to be located in membrane. WB:WBGene00044035 F27E5.7 Enriched in AFD; NSM; hypodermis; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00044036 ZK673.12 Enriched in FLP based on single-cell RNA-seq studies. Is affected by daf-2 and eat-2 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00044037 ZK892.8 Is affected by several genes including daf-16; eat-2; and etr-1 based on RNA-seq and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00044038 C47G2.6 Is affected by several genes including hsf-1; eat-2; and hpl-2 based on RNA-seq studies. WB:WBGene00044040 F54D5.16 Is affected by several genes including daf-16; hsf-1; and isp-1 based on RNA-seq and microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00044041 F57G9.6 Is affected by several genes including eat-2; atfs-1; and hpl-2 based on RNA-seq and microarray studies. Is affected by six chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044042 Y46G5A.37 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00044043 Y46G5A.38 Enriched in hypodermis and tail hypodermis based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including methylmercury hydroxide; 1-methylnicotinamide; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00044044 C08B6.14 Predicted to enable acid phosphatase activity and metal ion binding activity. WB:WBGene00044045 R11G10.3 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00044046 ZK666.13 Is affected by clk-1 and hsf-1 based on microarray and RNA-seq studies. Is affected by Colistin based on microarray studies. WB:WBGene00044047 Y57A10C.11 Predicted to be located in membrane. WB:WBGene00044048 F57G9.7 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00044049 sfxn-5 Predicted to enable transmembrane transporter activity. Predicted to be involved in mitochondrial transmembrane transport. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human SFXN5 (sideroflexin 5). WB:WBGene00044051 Y57A10A.37 Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00044052 Y57A10C.12 No description available WB:WBGene00044053 C01G12.12 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; clk-1; and unc-30 based on RNA-seq and microarray studies. Is affected by allantoin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00044054 C04H5.9 Is affected by several genes including rrf-3; eat-2; and raga-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Sodium Chloride; Rifampin; and Sirolimus based on RNA-seq studies. WB:WBGene00044056 Y53F4B.40 Is affected by several genes including mut-16; adr-1; and meg-3 based on RNA-seq studies. WB:WBGene00044057 F18A11.7 Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00044058 F17B5.6 Predicted to enable galactoside 2-alpha-L-fucosyltransferase activity. Predicted to be involved in macromolecule glycosylation. Predicted to be located in membrane. WB:WBGene00044059 T27C5.12 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00044061 tbc-12 Predicted to enable GTPase activator activity. Predicted to be involved in regulation of autophagosome assembly. Predicted to be located in autophagosome and recycling endosome. Is an ortholog of human TBC1D12 (TBC1 domain family member 12) and TBC1D14 (TBC1 domain family member 14). WB:WBGene00044062 snb-6 Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in vesicle fusion. Predicted to be located in plasma membrane. Predicted to be part of SNARE complex. Is an ortholog of human VAMP7 (vesicle associated membrane protein 7). WB:WBGene00044063 bpnt-1 Predicted to enable 3'(2'),5'-bisphosphate nucleotidase activity. Involved in dauer exit; defense response to Gram-negative bacterium; and regulation of neuronal signal transduction. Expressed in several structures, including tail. Is an ortholog of human BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1). WB:WBGene00044065 tag-229 Predicted to enable DNA binding activity. WB:WBGene00044066 fbxb-66 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ciliated neurons; and pharynx based on microarray; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nineteen chemicals including hydrogen sulfide; 1-methylnicotinamide; and methylmercuric chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00044067 zipt-7.1 Enables zinc ion transmembrane transporter activity. Involved in intracellular zinc ion homeostasis; multicellular organismal reproductive process; and regulation of reproductive process. Located in membrane. Expressed in hypodermis; neurons; spermatocyte; ventral nerve cord; and vulva. WB:WBGene00044068 syd-9 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nuclear speck. Expressed in ASEL; ASER; muscle cell; nerve ring neurons; and neurons. WB:WBGene00044069 hat-1 Predicted to enable histone H4 acetyltransferase activity. Predicted to be involved in subtelomeric heterochromatin formation. Predicted to be located in chromosome, telomeric region and nucleus. Expressed in germ line. Is an ortholog of human HAT1 (histone acetyltransferase 1). WB:WBGene00044070 set-18 Enables histone H3K36 methyltransferase activity. Predicted to be involved in chromatin remodeling. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Expressed in body wall musculature; non-striated muscle; pharynx; and vulva. Is an ortholog of human SMYD1 (SET and MYND domain containing 1) and SMYD3 (SET and MYND domain containing 3). WB:WBGene00044071 dhhc-14 Predicted to enable palmitoyltransferase activity. Predicted to be located in Golgi membrane. Expressed in body wall musculature and neurons. Is an ortholog of human ZDHHC13 (zinc finger DHHC-type palmitoyltransferase 13) and ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17). WB:WBGene00044072 ham-3 Enables DNA-binding transcription factor binding activity; transcription coactivator activity; and transcription corepressor activity. Involved in determination of adult lifespan; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including HSNL and HSNR. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 11. Is an ortholog of human SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1); SMARCD2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2); and SMARCD3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3). WB:WBGene00044073 tag-244 Involved in innate immune response. WB:WBGene00044074 mltn-5 Predicted to be located in membrane. WB:WBGene00044077 pacs-1 Predicted to be involved in protein localization to plasma membrane. Expressed in several structures, including excretory cell; intestine; neurons; pharynx; and vulva. Human ortholog(s) of this gene implicated in Schuurs-Hoeijmakers Syndrome and developmental and epileptic encephalopathy 66. Is an ortholog of human PACS1 (phosphofurin acidic cluster sorting protein 1) and PACS2 (phosphofurin acidic cluster sorting protein 2). WB:WBGene00044078 tag-243 Predicted to enable actin binding activity. Predicted to be involved in positive regulation of Rho protein signal transduction. WB:WBGene00044079 tag-241 Enriched in several structures, including body wall muscle cell; head mesodermal cell; intestinal muscle; neurons; and rectal muscle based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seventeen chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies. Human MTCL1 enables microtubule binding activity. Is an ortholog of human MTCL1 (microtubule crosslinking factor 1) and MTCL2 (microtubule crosslinking factor 2). WB:WBGene00044080 D1086.10 Enriched in AFD; cephalic sheath cell; and hypodermis based on tiling array; RNA-seq; and proteomic studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; RNA-seq; and microarray studies. Is affected by twenty-one chemicals including Ethanol; manganese chloride; and mianserin based on RNA-seq; proteomic; and microarray studies. WB:WBGene00044081 D1086.11 Enriched in several structures, including ABalaaaarl; ABalaaaarr; dopaminergic neurons; germ line; and spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq; microarray; and proteomic studies. Is affected by thirteen chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq; proteomic; and microarray studies. WB:WBGene00044082 D1086.12 Enriched in body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including rotenone; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044083 tin-9.2 Predicted to enable metal ion binding activity. Involved in inductive cell migration; regulation of growth; and reproduction. Located in mitochondrion. Is an ortholog of human TIMM10B (translocase of inner mitochondrial membrane 10B). WB:WBGene00044084 sre-46 Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00044085 Y105C5B.30 Is affected by several genes including skn-1; eat-2; and smn-1 based on RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and Psoralens based on RNA-seq studies. WB:WBGene00044086 clec-228 Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including daf-16; daf-12; and tph-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily. WB:WBGene00044087 C45H4.18 Predicted to be located in membrane. WB:WBGene00044088 oac-2 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. WB:WBGene00044089 srbc-31 Predicted to be located in membrane. WB:WBGene00044090 srbc-33 Predicted to be located in membrane. WB:WBGene00044091 srbc-60 Predicted to be located in membrane. WB:WBGene00044092 srbc-71 Predicted to be located in membrane. WB:WBGene00044093 srbc-72 Is affected by tatn-1 and clk-1 based on RNA-seq and microarray studies. WB:WBGene00044094 fitm-2 Predicted to enable acyl-coenzyme A diphosphatase activity. Involved in lipid droplet formation. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Siddiqi syndrome. Is an ortholog of human FITM2 (fat storage inducing transmembrane protein 2). WB:WBGene00044095 srh-121 Is affected by clk-1; etr-1; and mut-2 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00044096 srh-96 Is affected by several genes including pgl-1; cat-2; and glh-1 based on RNA-seq studies. WB:WBGene00044097 srh-64 Is affected by eat-2 and daf-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044099 srd-75 Enriched in muscle cell and neurons based on microarray studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Serpentine type 7TM GPCR chemoreceptor Srd and 7TM GPCR, serpentine receptor class d (Srd). WB:WBGene00044100 srbc-27 Predicted to be located in membrane. WB:WBGene00044101 srbc-28 No description available WB:WBGene00044102 srbc-46 No description available WB:WBGene00044103 srbc-47 No description available WB:WBGene00044104 srbc-53 Is affected by clk-1 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00044105 srbc-55 Predicted to be located in membrane. WB:WBGene00044106 srbc-84 Predicted to be located in membrane. WB:WBGene00044107 chca-1 Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in copper ion transmembrane transport and intracellular copper ion homeostasis. Predicted to be located in late endosome membrane. WB:WBGene00044109 K02E11.10 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-five chemicals including hydrogen sulfide; Ethanol; and Nitric Oxide based on microarray and RNA-seq studies. WB:WBGene00044112 srm-5 Predicted to be located in membrane. Expressed in ASHL; ASHR; ASIL; ASIR; and RIH. WB:WBGene00044113 C54F6.15 Enriched in dopaminergic neurons and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by four chemicals including indole; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00044114 srxa-11 Predicted to be located in membrane. WB:WBGene00044115 srxa-12 Predicted to be located in membrane. WB:WBGene00044116 srxa-13 Predicted to be located in membrane. WB:WBGene00044117 srsx-10 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00044119 srh-191 Is affected by xpf-1 and qui-1 based on RNA-seq studies. Is affected by Rifampin based on RNA-seq studies. WB:WBGene00044120 C36B1.13 Predicted to be located in membrane. WB:WBGene00044121 gcp-2.3 Is affected by several genes including daf-2; eat-2; and pmk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube and Diazinon based on RNA-seq and microarray studies. WB:WBGene00044122 osp-1 Predicted to be located in membrane. WB:WBGene00044124 srsx-15 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00044125 srsx-16 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. WB:WBGene00044126 srsx-23 Is affected by dpy-21; daf-2; and ints-8 based on RNA-seq and microarray studies. WB:WBGene00044127 BE10.5 Enriched in NSM; amphid sheath cell; sensory neurons; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044128 BE10.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; aak-2; and prg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00044129 C01B9.3 Is affected by adr-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00044130 C05B5.10 Enriched in muscle cell based on RNA-seq studies. Is affected by clk-1; adr-1; and eat-2 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00044131 Y45G12C.16 Is affected by several genes including daf-16; daf-2; and hsf-1 based on RNA-seq; proteomic; and microarray studies. Is affected by CGP37157 and Ketamine based on RNA-seq studies. WB:WBGene00044132 C23H4.8 Enriched in germline precursor cell; hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by twelve chemicals including bisphenol A; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044133 C44C10.12 Is affected by hpl-2 and dpy-21 based on tiling array and RNA-seq studies. WB:WBGene00044134 D1025.10 Enriched in AFD; body wall muscle cell; neurons; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq; tiling array; and microarray studies. Is affected by rotenone based on RNA-seq studies. WB:WBGene00044135 F08G12.11 Enriched in ASER and neuronal sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; set-2; and drh-3 based on microarray and RNA-seq studies. Is affected by four chemicals including Tunicamycin; multi-walled carbon nanotube; and Oligosaccharides based on microarray and RNA-seq studies. WB:WBGene00044136 F23D12.8 Enriched in DA neuron; VA neuron; and body wall muscle cell based on tiling array studies. Is affected by several genes including csr-1; spn-4; and mir-34 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044137 F28H6.8 Enriched in several structures, including ABalaapppp; ABalapaapp; ABalappppa; ABprpapppa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; D-glucose; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00044138 sssh-1 Predicted to be involved in regulation of cholinergic synaptic transmission and sleep. WB:WBGene00044139 F42D1.4 Enriched in AVE; coelomocyte; muscle cell; and in male based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; smn-1; and etr-1 based on RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and atracurium based on RNA-seq studies. WB:WBGene00044140 F42F12.11 Is affected by several genes including eat-2; pgl-1; and glh-1 based on tiling array and RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00044141 H03G16.6 Predicted to be located in membrane. WB:WBGene00044142 H13N06.7 Predicted to enable microtubule binding activity. Predicted to be located in microtubule cytoskeleton and sperm flagellum. WB:WBGene00044143 K09E9.4 Predicted to enable cAMP-dependent protein kinase inhibitor activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00044144 znf-474 Enriched in neurons; rectal epithelial cell; and rectum based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including stavudine; Zidovudine; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: zinc-finger of a C2HC-type and Zinc finger C2HC domain-containing protein. Is an ortholog of human ZNF474 (zinc finger protein 474). WB:WBGene00044145 M163.9 Predicted to be located in membrane. WB:WBGene00044146 M163.10 Predicted to be located in membrane. WB:WBGene00044147 M163.11 Enriched in ABplppaaaap; ABprppaaaap; and nerve ring neurons based on single-cell RNA-seq studies. Is affected by several genes including eat-2; elt-2; and pgl-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00044148 T08D10.4 Enriched in AINL; AINR; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; nhr-49; and alg-1 based on RNA-seq and microarray studies. Is affected by five chemicals including hydrogen sulfide; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00044149 T24D5.6 Enriched in NSM; body wall muscle cell; and hypodermis based on tiling array studies. Is affected by several genes including eat-2; unc-30; and csr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including rotenone; D-glucose; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044150 VB0395L.1 Predicted to enable aminopeptidase activity. WB:WBGene00044151 W04G3.12 Enriched in PLM and body wall muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube and Rifampin based on RNA-seq studies. WB:WBGene00044152 W04G3.10 Predicted to enable phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion and phospholipid metabolic process. WB:WBGene00044153 W04G3.11 Is affected by several genes including daf-2; daf-12; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00044154 Y7A5A.10 Enriched in NSM and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including clk-1; mex-3; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00044155 Y7A5A.11 Enriched in body wall muscle cell and in male based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and pgl-1 based on RNA-seq studies. Is affected by six chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044156 Y66C5A.1 Enriched in PDB; body wall muscle cell; cholinergic neurons; enteric muscle; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq studies. WB:WBGene00044157 Y66C5A.2 Enriched in NSM; Z1.p; Z4.a; gon_male_dtc anterior; and gon_male_dtc posterior based on tiling array and RNA-seq studies. Is affected by rsr-2 and clk-1 based on tiling array and microarray studies. WB:WBGene00044158 Y53C12A.8 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by ten chemicals including Tunicamycin; manganese chloride; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00044159 F26C11.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; tph-1; and csr-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00044160 W10C6.2 Is affected by several genes including mex-3; hpl-2; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: Small ribosomal subunit protein uS5 domain 2-type fold, subgroup and Ribosomal protein uS5 domain 2-type superfamily. WB:WBGene00044161 C47G2.8 Enriched in AFD and intestine based on RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and hsf-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Rifampin; Sirolimus; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00044162 F49C5.10 Enriched in several structures, including ABplpppaaa; ABprpppaaa; RIB; g2; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; aak-2; and unc-30 based on tiling array; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00044163 F49C5.11 Enriched in AFD; ASER; hypodermis; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercury hydroxide; Tunicamycin; and manganese chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00044164 Y46G5A.39 Enriched in body wall muscle cell; neurons; and pm7 based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including tryptophan; Psoralens; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00044166 C54C6.7 Enriched in AVD; intestine; muscle cell; and rectal epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; stavudine; and Rifampin based on RNA-seq studies. WB:WBGene00044167 C36A4.11 Enriched in several structures, including FLP; GLR; head mesodermal cell; mc2; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on RNA-seq and microarray studies. Is affected by ten chemicals including Tunicamycin; Sodium Chloride; and bisphenol A based on microarray and RNA-seq studies. WB:WBGene00044168 M05D6.10 Enriched in AVK and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq studies. Is affected by four chemicals including rotenone; Rifampin; and Psoralens based on RNA-seq studies. WB:WBGene00044169 C06C3.10 Enriched in several structures, including germline precursor cell; sensory neurons; somatic gonad precursor; tail hypodermis; and ventral cord blast cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ras-mediated vulval-induction antagonist and Protein LIN-8. WB:WBGene00044170 Y51B9A.10 Is affected by several genes including daf-2; smg-2; and etr-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044171 Y54E2A.13 No description available WB:WBGene00044174 fipr-5 Enriched in OLLL; OLLR; arcade cell; germ line; and pharyngeal-intestinal valve cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Ethanol; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00044175 fipr-9 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including Ethanol; manganese chloride; and D-glucose based on RNA-seq studies. WB:WBGene00044176 C30G7.2 Enriched in B cell; excretory gland cell; head mesodermal cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including glp-1; pgl-1; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00044177 C30G7.3 Enriched in germ line; hypodermis; and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Ethanol; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00044178 C30G7.4 Predicted to be located in membrane. WB:WBGene00044179 C30G7.5 Predicted to be located in membrane. WB:WBGene00044180 C47E8.11 Enriched in coelomocyte; intestine; neurons; somatic gonad precursor; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including manganese chloride; D-glucose; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00044181 F09C6.11 Enriched in ADE sheath cell; PVT; anterior ganglion; hyp3; and pharyngeal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including nhr-49; aak-2; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including tryptophan; multi-walled carbon nanotube; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00044182 F09C6.12 Predicted to be located in motile cilium. WB:WBGene00044183 F09C6.13 Enriched in excretory cell; germ line; muscle cell; and pharynx based on tiling array and RNA-seq studies. Is affected by several genes including glp-1; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fifteen chemicals including tryptophan; Tunicamycin; and sodium arsenite based on microarray and RNA-seq studies. WB:WBGene00044184 F11A5.16 Enriched in germ line based on RNA-seq studies. Is affected by rsr-2 and smg-2 based on tiling array and RNA-seq studies. WB:WBGene00044185 F14F8.14 Enriched in Z1.p; Z4.a; gon_male_dtc anterior; and gon_male_dtc posterior based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by triclosan based on microarray studies. WB:WBGene00044187 ttll-9 Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to be located in cilium. Is an ortholog of human TTLL9 (tubulin tyrosine ligase like 9). WB:WBGene00044188 F28F8.9 Enriched in ABplapaaap; ABprapaaap; AFD; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and sek-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including rotenone; manganese chloride; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044189 F36D3.14 Is affected by daf-2 and set-2 based on microarray and RNA-seq studies. WB:WBGene00044191 F43D2.6 Predicted to be located in membrane. WB:WBGene00044192 F46B6.13 Enriched in AFD; NSM; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044193 F47B8.13 Enriched in AMshL and AMshR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044194 F47B8.14 Is affected by several genes including daf-2; daf-12; and pgl-1 based on tiling array and RNA-seq studies. Is affected by Colistin based on microarray studies. WB:WBGene00044195 F49A5.10 Enriched in ABalappaap; head mesodermal cell; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including hpl-2; set-2; and klf-1 based on tiling array and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00044196 F55C9.12 Is affected by several genes including eat-2; clk-1; and adr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044197 fbxb-63 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; NSM; and SMB based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including hydrogen sulfide; indole; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00044198 F56H9.6 Enriched in anterior ganglion and arc ant V based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by Zidovudine and cholesterol based on RNA-seq studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00044199 F57B1.8 Is affected by several genes including daf-2; hpl-2; and dpy-21 based on RNA-seq and microarray studies. WB:WBGene00044200 H37A05.4 Enriched in several structures, including ABalppppppp; ABarpapaapp; head mesodermal cell; motor neurons; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including rotenone; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044201 H39E23.3 Predicted to enable microtubule binding activity. WB:WBGene00044202 K10G4.10 Enriched in NSM and neurons based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; clk-1; and tph-1 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube and paraquat based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00044203 T02E9.6 Predicted to enable hydrolase activity, acting on glycosyl bonds. Predicted to be involved in xylan catabolic process. WB:WBGene00044204 suds-3 Enriched in AFD and germ line based on RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq; microarray; and proteomic studies. Is affected by nine chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044205 T13F3.8 Predicted to be located in membrane. WB:WBGene00044206 T26H5.9 Predicted to enable endonuclease activity. WB:WBGene00044207 Y6G8.5 Enriched in NSM and intestine based on tiling array and RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and lin-35 based on RNA-seq and microarray studies. Is affected by ten chemicals including multi-walled carbon nanotube; bisphenol A; and Zidovudine based on RNA-seq studies. WB:WBGene00044208 Y6G8.6 Predicted to be located in membrane. WB:WBGene00044209 Y32F6A.6 Enriched in anterior gonadal sheath cell; germ line; posterior gonadal sheath cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and sek-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00044210 Y51A2D.21 Predicted to be located in membrane. WB:WBGene00044211 Y60A3A.25 Enriched in AINL and AINR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00044212 Y68A4A.13 Enriched in head mesodermal cell and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; tiling array; and microarray studies. Is affected by seventeen chemicals including methylmercury hydroxide; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00044213 Y102A5C.36 Enriched in AVL; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and elt-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; rotenone; and allantoin based on microarray and RNA-seq studies. WB:WBGene00044215 ZK228.10 Is affected by several genes including skn-1; hsf-1; and hpl-2 based on tiling array and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00044216 C47E8.10 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including manganese chloride; metformin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00044217 F23D12.9 Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including allantoin; metformin; and Rifampin based on RNA-seq studies. WB:WBGene00044218 F23H12.10 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and pgl-1 based on RNA-seq studies. Is affected by eight chemicals including rotenone; stavudine; and Psoralens based on RNA-seq studies. WB:WBGene00044219 F28F8.10 Is affected by several genes including pgl-1; unc-30; and glh-1 based on RNA-seq studies. Is affected by rotenone; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00044220 Y102A5C.35 Is affected by several genes including daf-2; daf-18; and unc-30 based on RNA-seq and microarray studies. Is affected by five chemicals including Alovudine; Rifampin; and Psoralens based on RNA-seq studies. WB:WBGene00044221 F41G3.18 Predicted to be located in membrane. WB:WBGene00044222 T16G12.10 Enriched in MSpppaaa; Z1; Z4; head mesodermal cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044224 F17C8.8 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on RNA-seq studies. WB:WBGene00044225 C38D4.10 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and prg-1 based on RNA-seq studies. Is affected by Rifampin; allantoin; and atracurium based on RNA-seq studies. WB:WBGene00044226 K08E5.4 Is affected by daf-16; etr-1; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00044227 C07A9.13 Enriched in several structures, including ABplppppap; PLM; RIH; accessory cell; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by ten chemicals including D-glucose; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00044228 T03F6.7 Enriched in ASJL; ASJR; URXL; URXR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including drh-3; hlh-26; and rsr-2 based on tiling array and RNA-seq studies. WB:WBGene00044229 T03F6.8 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Tunicamycin; manganese chloride; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00044230 C36E8.6 Enriched in GABAergic neurons based on RNA-seq studies. Is affected by several genes including drh-3; let-418; and ubc-9 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044232 C18D11.7 Enriched in several structures, including ABalpppappp; ABalppppppa; ABplaapappp; ABplapppapp; and amphid neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including skn-1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00044233 dolk-1 Predicted to enable dolichol kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Im. Is an ortholog of human DOLK (dolichol kinase). WB:WBGene00044234 Y111B2A.37 No description available WB:WBGene00044235 C06A1.7 Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by silicon dioxide nanoparticle and adsorbable organic bromine compound based on RNA-seq and microarray studies. WB:WBGene00044236 C17E4.11 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human EEF1AKMT4 (EEF1A lysine methyltransferase 4). WB:WBGene00044237 pals-9 Enriched in PLM and cephalic sheath cell based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044238 C30H6.12 Enriched in body wall muscle cell; intestine; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including multi-walled carbon nanotube; Cadmium Chloride; and metformin based on RNA-seq and microarray studies. WB:WBGene00044239 C33D9.10 Predicted to be located in motile cilium. WB:WBGene00044240 C47E12.14 Enriched in PLM and amphid sheath cell based on RNA-seq studies. Is affected by several genes including hpl-2; drh-3; and etr-1 based on tiling array and RNA-seq studies. WB:WBGene00044241 C53D6.11 Predicted to be located in membrane. WB:WBGene00044242 C54C8.12 Enriched in NSM and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including tryptophan; rotenone; and mianserin based on microarray and RNA-seq studies. WB:WBGene00044243 F16C3.4 Enriched in amphid sheath cell; germ line; intestine; sensory neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Psoralens; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00044244 F26D10.13 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and metformin based on RNA-seq studies. WB:WBGene00044245 F32A7.8 Predicted to be located in membrane. WB:WBGene00044246 F36D1.10 Is affected by rsr-2 and dpy-21 based on tiling array and RNA-seq studies. WB:WBGene00044247 F36H2.4 Predicted to be located in membrane. WB:WBGene00044249 F55B11.6 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; Alovudine; and Psoralens based on RNA-seq studies. WB:WBGene00044250 F56G4.7 Enriched in AFD; germ line; and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; manganese chloride; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00044251 F59C6.12 Enriched in ABalapaaaa; ABalappaap; ABalappapa; germ line; and germline precursor cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and isp-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including hydrogen sulfide; Zidovudine; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF4505) and Protein of unknown function DUF4505. Is an ortholog of human C8orf82 (chromosome 8 open reading frame 82). WB:WBGene00044253 M117.6 Predicted to be located in membrane. WB:WBGene00044256 Y45F10C.6 Enriched in DA neuron; VA neuron; and excretory cell based on tiling array studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00044257 Y45F10D.16 Predicted to be located in membrane. WB:WBGene00044258 Y57G11C.51 Enriched in several structures, including ABalapppaa; ABalpppappp; AIY; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00044259 Y73F8A.36 Enriched in F cell and U cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-60 based on RNA-seq and microarray studies. Is affected by five chemicals including stavudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00044260 Y87G2A.19 Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. WB:WBGene00044261 Y87G2A.20 Enriched in several structures, including ABplapaaap; ABprapaaap; AVG; RIM; and command interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including tryptophan; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00044262 Y95D11A.2 Is affected by several genes including daf-16; pgl-1; and unc-30 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044263 Y105C5A.26 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array and microarray studies. WB:WBGene00044264 Y105E8A.32 Enriched in OLLL and OLLR based on single-cell RNA-seq studies. Is affected by several genes including clk-1; mdt-15; and smg-2 based on microarray and RNA-seq studies. Is affected by adsorbable organic bromine compound and allantoin based on microarray studies. WB:WBGene00044265 Y105E8B.11 Enriched in AVK and NSM based on tiling array and RNA-seq studies. Is affected by several genes including clk-1; aak-2; and set-2 based on RNA-seq and microarray studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00044266 ZK39.9 Is affected by hpl-2 and rsr-2 based on tiling array studies. WB:WBGene00044267 F41D3.12 Is affected by clk-1 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00044268 T27E7.10 Is affected by several genes including daf-2; clk-1; and sek-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; stavudine; and metformin based on RNA-seq studies. WB:WBGene00044270 F35E2.10 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pmk-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; atracurium; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00044271 nspa-2 Enriched in neurons based on microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including hydrogen sulfide; multi-walled carbon nanotube; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00044272 nspa-4 Enriched in neurons and rectal epithelium based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twenty chemicals including hydrogen sulfide; Ethanol; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00044273 nspa-6 Enriched in AVG; RIM; and command interneuron based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including hydrogen sulfide; multi-walled carbon nanotube; and metformin based on microarray and RNA-seq studies. WB:WBGene00044274 nspa-7 Enriched in AVG; RIM; and command interneuron based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00044275 nspa-10 Enriched in AIZL and AIZR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by hydrogen sulfide based on microarray studies. WB:WBGene00044276 nspa-11 Is affected by hpl-2 and daf-2 based on RNA-seq and microarray studies. Is affected by Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00044277 nspa-12 Is affected by several genes including daf-16; daf-2; and pgl-1 based on microarray and RNA-seq studies. WB:WBGene00044278 F09C6.14 Enriched in CANL; CANR; and RID based on single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and set-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00044279 grl-32 Is affected by several genes including daf-2; sir-2.1; and pmk-1 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044280 W02A2.9 Predicted to be located in membrane. WB:WBGene00044281 R04A9.7 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in cytoplasm and nucleoplasm. Is an ortholog of human RPS6KB1 (ribosomal protein S6 kinase B1). WB:WBGene00044282 T19H12.12 Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00044283 spp-22 Enriched in several structures, including AWC; OLQ; arcade cell; head mesodermal cell; and pharyngeal cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00044284 spp-21 Is affected by several genes including daf-16; daf-2; and elt-2 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including Tunicamycin; indole; and D-glucose based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. WB:WBGene00044285 thn-8 Is affected by elli-1; eat-2; and etr-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044286 ugt-35 Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of human UGT3A1 (UDP glycosyltransferase family 3 member A1) and UGT3A2 (UDP glycosyltransferase family 3 member A2). WB:WBGene00044287 nspg-3 Enriched in intestine based on tiling array studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Rifampin; Sirolimus; and allantoin based on RNA-seq studies. WB:WBGene00044288 F30H5.5 Enriched in germ line and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00044289 Y37F4.8 Enriched in AVG; g1AL; g1AR; and g1P based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; D-glucose; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00044290 B0035.18 Predicted to be located in mitochondrial inner membrane. WB:WBGene00044291 C25F9.10 Predicted to be located in membrane. WB:WBGene00044292 F56D6.8 Enriched in body wall muscle cell and hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including rotenone; Tunicamycin; and Cadmium Chloride based on RNA-seq and microarray studies. WB:WBGene00044293 epic-3 Is affected by several genes including let-60; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube; silicon dioxide nanoparticle; and nitroguanidine based on RNA-seq and microarray studies. WB:WBGene00044294 C01B10.11 Enriched in several structures, including anterior ganglion; anterior hypodermis; interfacial epithelial cell; sensory neurons; and tail hypodermis based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on proteomic; microarray; and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; methylmercury hydroxide; and stavudine based on RNA-seq; proteomic; and microarray studies. WB:WBGene00044295 C09E7.10 Predicted to be located in membrane. WB:WBGene00044296 F10C1.9 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalpppappp; amphid neurons; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including rotenone; D-glucopyranose; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Lamin tail domain superfamily. WB:WBGene00044297 C25B8.8 Predicted to be located in membrane. WB:WBGene00044298 T23B7.2 Predicted to be located in membrane. WB:WBGene00044299 C42D8.9 Enriched in AFD; ASKL; ASKR; intestine; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Sodium Chloride; and metformin based on RNA-seq and microarray studies. WB:WBGene00044300 D1022.9 Predicted to be located in membrane. WB:WBGene00044301 lgc-28 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00044302 F28E10.5 Enriched in several structures, including NSM; germ line; hyp3; interfacial epithelial cell; and intestine based on RNA-seq; tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00044303 hst-3.2 Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Expressed in epithelial cell; hypodermis; neurons; and vulva. Human ortholog(s) of this gene implicated in several diseases, including colon cancer; hereditary angioedema; and lung non-small cell carcinoma. Is an ortholog of human HS3ST2 (heparan sulfate-glucosamine 3-sulfotransferase 2). WB:WBGene00044304 F52B10.3 Predicted to be located in membrane. WB:WBGene00044305 rad-8 Predicted to enable oxidoreductase activity. Involved in several processes, including defense response to other organism; positive regulation of growth rate; and response to superoxide. Located in mitochondrion. Expressed in several structures, including intestine; muscle cell; neurons; and pharynx. Human ortholog(s) of this gene implicated in optic atrophy 10. Is an ortholog of human RTN4IP1 (reticulon 4 interacting protein 1). WB:WBGene00044306 F58F9.8 Enriched in NSM and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00044307 F58F9.9 Enriched in male based on RNA-seq studies. Is affected by several genes including csr-1; xpf-1; and spe-44 based on tiling array and RNA-seq studies. WB:WBGene00044308 F58F9.10 Enriched in AQR; PQR; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including clk-1; drh-3; and smg-2 based on microarray and RNA-seq studies. WB:WBGene00044309 F58F9.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including clk-1; hpl-2; and dpy-21 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044310 H20J04.9 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00044311 K04C2.7 Predicted to be located in membrane. WB:WBGene00044312 K04C2.8 Enriched in ABplapaaap; ABprapaaap; pm6; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044313 M02D8.7 Enriched in neurons and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by Acrylamide and nitroguanidine based on microarray studies. WB:WBGene00044314 fbxb-33 Enriched in neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00044315 F41G3.20 Is affected by several genes including daf-2; daf-18; and isp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including resveratrol; Hydrolyzable Tannins; and Humic Substances based on microarray studies. Is predicted to encode a protein with the following domains: CC domain; ShK domain-like; and ShKT domain. WB:WBGene00044316 F41G3.21 Enriched in g1AL; g1AR; g1P; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by eleven chemicals including Zidovudine; Sodium Chloride; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00044317 F41G3.19 Enriched in g1P based on single-cell RNA-seq studies. Is affected by several genes including dpy-21; cnd-1; and etr-1 based on tiling array and RNA-seq studies. Is affected by nitroguanidine based on microarray studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00044318 tag-267 Enriched in germ line; hypodermis; intestine; neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; proteomic; and tiling array studies. Is affected by nine chemicals including stavudine; Rifampin; and allantoin based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044319 tag-266 Predicted to be located in membrane. Used to study cancer. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Is an ortholog of human CHIC2 (cysteine rich hydrophobic domain 2). WB:WBGene00044321 mrps-30 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion and ribosome. Predicted to be part of mitochondrial large ribosomal subunit. Is an ortholog of human MRPS30 (mitochondrial ribosomal protein S30). WB:WBGene00044322 tag-280 Predicted to be involved in positive regulation of plasminogen activation. Predicted to be located in plasma membrane. Is an ortholog of human PLGRKT (plasminogen receptor with a C-terminal lysine). WB:WBGene00044323 tag-281 Predicted to be involved in positive regulation of plasminogen activation. Predicted to be located in plasma membrane. Is an ortholog of human PLGRKT (plasminogen receptor with a C-terminal lysine). WB:WBGene00044324 ufm-1 Predicted to be involved in protein ufmylation. Predicted to be located in cytoplasm and nucleus. Expressed in egg-laying apparatus; hermaphrodite gonad; intestine; and seam cell. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 14. Is an ortholog of human UFM1 (ubiquitin fold modifier 1). WB:WBGene00044325 tag-321 Located in mitochondrion. Is an ortholog of human TMEM65 (transmembrane protein 65). WB:WBGene00044326 tag-322 Predicted to be part of tRNA-splicing ligase complex. Is an ortholog of human FAM98A (family with sequence similarity 98 member A); FAM98B (family with sequence similarity 98 member B); and FAM98C (family with sequence similarity 98 member C). WB:WBGene00044329 cpsf-4 Predicted to enable RNA binding activity; enzyme binding activity; and zinc ion binding activity. Predicted to be located in cytoplasm. Is an ortholog of human CPSF4 (cleavage and polyadenylation specific factor 4). WB:WBGene00044330 alr-1 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including amphid sensory organ development; epidermis morphogenesis; and sensory perception of touch. Located in nucleus. Expressed in several structures, including anterior hypodermis; neurons; pseudocoelom; socket cell; and somatic nervous system. Used to study non-syndromic X-linked intellectual disability 1. Human ortholog(s) of this gene implicated in several diseases, including X-linked lissencephaly 2; X-linked recessive disease (multiple); and gastrointestinal system cancer (multiple). Is an ortholog of human ALX4 (ALX homeobox 4) and ARX (aristaless related homeobox). WB:WBGene00044331 clec-25 Predicted to be located in membrane. WB:WBGene00044332 clec-36 Predicted to be located in membrane. WB:WBGene00044333 C01G12.13 Enriched in AIZ; germ line; hypodermis; interfacial epithelial cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including manganese chloride; D-glucose; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00044334 W06G6.14 No description available WB:WBGene00044335 Y51A2D.22 No description available WB:WBGene00044336 Y7A5A.12 No description available WB:WBGene00044337 nspc-2 Enriched in AVG; RIM; and command interneuron based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and isp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Ethanol; Rifampin; and mianserin based on RNA-seq and microarray studies. WB:WBGene00044338 nspc-3 Enriched in AVG; RIM; command interneuron; and excretory gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; tiling array; and microarray studies. Is affected by seven chemicals including mianserin; D-glucose; and metformin based on RNA-seq studies. WB:WBGene00044339 nspc-4 Enriched in excretory gland cell and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including Ethanol; rotenone; and mianserin based on RNA-seq and microarray studies. WB:WBGene00044340 nspc-5 Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by mianserin and triclosan based on RNA-seq and microarray studies. WB:WBGene00044341 ave-1 Enriched in germ line and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; pgl-1; and atfs-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 1. Is predicted to encode a protein with the following domains: SAM domain (Sterile alpha motif); Sterile alpha motif/pointed domain superfamily; and Sterile alpha motif domain. Is an ortholog of human SAMD10 (sterile alpha motif domain containing 10) and SAMD12 (sterile alpha motif domain containing 12). WB:WBGene00044342 T05B11.7 Enriched in several structures, including ABalaapppa; ABalaappppa; ABalapaapa; ABalapaappa; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; lin-4; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00044343 clec-77 Is affected by several genes including skn-1; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Tunicamycin; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00044344 mrpl-39 Predicted to enable nucleotide binding activity. Predicted to be located in mitochondrion. Is an ortholog of human MRPL39 (mitochondrial ribosomal protein L39). WB:WBGene00044345 Y48G1C.12 Predicted to be involved in anaphase-promoting complex-dependent catabolic process and cell division. Predicted to be part of anaphase-promoting complex. Is an ortholog of human ANAPC10 (anaphase promoting complex subunit 10). WB:WBGene00044346 Y59E9AL.8 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by multi-walled carbon nanotube; Doxycycline; and paraquat based on RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00044347 Y71G12B.30 Predicted to enable protein serine/threonine phosphatase activity. Predicted to be located in cytoplasm and nucleus. WB:WBGene00044348 Y71G12B.31 Predicted to enable protein tyrosine phosphatase activity. Predicted to be located in membrane. WB:WBGene00044349 Y71G12B.32 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including bisphenol S; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: F-box protein she-1-like. WB:WBGene00044350 Y73B6BL.44 Enriched in seam cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by twelve chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00044352 ZK381.8 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00044353 ZK418.10 Predicted to be located in nucleus. WB:WBGene00044354 ZK418.11 Predicted to be located in nucleus. WB:WBGene00044355 ZK563.7 Predicted to enable GDP phosphatase activity and UDP phosphatase activity. Predicted to be involved in proteoglycan biosynthetic process. Human ortholog(s) of this gene implicated in Desbuquois dysplasia and multiple epiphyseal dysplasia 7. Is an ortholog of human CANT1 (calcium activated nucleotidase 1). WB:WBGene00044356 W02D7.12 Enriched in body wall muscle cell and in male based on tiling array and RNA-seq studies. Is affected by several genes including dpy-10; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00044357 nspc-6 Enriched in neurons based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including Ethanol; mianserin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00044358 Y71G12B.33 Predicted to be located in membrane. WB:WBGene00044359 C16C4.17 Enriched in several structures, including ABarppaapp; ABarpppapp; FLP; rectal epithelial cell; and rectum based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and prg-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Tunicamycin; paraquat; and Colistin based on microarray and RNA-seq studies. WB:WBGene00044360 C33C12.11 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. WB:WBGene00044361 K09F6.11 Enriched in intestine based on RNA-seq studies. Is affected by several genes including elt-2; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by four chemicals including rotenone; multi-walled carbon nanotube; and stavudine based on RNA-seq studies. WB:WBGene00044362 F42G2.7 Predicted to enable phytanoyl-CoA dioxygenase activity. Predicted to be involved in fatty acid alpha-oxidation. WB:WBGene00044363 F22E5.21 Enriched in germ line; mc2DL; mc2DR; and mc2V based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including hydrogen sulfide; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF684) and Protein of unknown function DUF684. WB:WBGene00044364 nspf-1 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-39 based on RNA-seq; tiling array; and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044365 nspf-2 Enriched in male based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00044366 nspf-3 Enriched in AVK; DA neuron; VA neuron; dopaminergic neurons; and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00044367 T05A8.8 Enriched in Z1.p; Z4.a; male distal tip cell; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including pgl-1; aak-2; and unc-30 based on RNA-seq and microarray studies. Is affected by cholesterol and Colistin based on RNA-seq and microarray studies. WB:WBGene00044368 K12H6.10 Enriched in amphid sheath cell; body wall muscle cell; germline precursor cell; hypodermis; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including let-60; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Chlorpyrifos and Diazinon based on microarray studies. WB:WBGene00044369 irld-67 Enriched in AVA; GABAergic neurons; NSM; and neurons based on tiling array and RNA-seq studies. Is affected by clk-1 and daf-2 based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00044370 C41H7.9 Enriched in AFD and intestine based on RNA-seq studies. Is affected by several genes including daf-16; clk-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by six chemicals including hydrogen sulfide; Rifampin; and allantoin based on microarray and RNA-seq studies. WB:WBGene00044371 ZC239.20 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00044372 ZC239.21 Enriched in ABalappaap; RICL; RICR; XXXL; and XXXR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including rotenone; multi-walled carbon nanotube; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00044373 C17F4.11 Enriched in ABplpapppa; head mesodermal cell; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including elt-2; clk-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00044374 C17F4.12 Enriched in RMED and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and pmk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; multi-walled carbon nanotube; and Sodium Chloride based on microarray and RNA-seq studies. WB:WBGene00044375 F39E9.14 Is affected by eat-2; mex-3; and lag-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044376 Y49F6B.12 Enriched in AFD; dopaminergic neurons; hypodermis; and neuronal sheath cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including methylmercury hydroxide; Tunicamycin; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00044377 Y49F6B.13 Enriched in male based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and tph-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Alovudine; stavudine; and allantoin based on RNA-seq studies. WB:WBGene00044378 Y49F6B.14 Is affected by rsr-2 and clk-1 based on tiling array and microarray studies. WB:WBGene00044379 ifas-1 Predicted to enable actin filament binding activity. Predicted to be involved in actin filament polymerization. Predicted to be located in actin cytoskeleton. WB:WBGene00044380 T24E12.12 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00044381 K10G6.5 Predicted to be located in membrane. WB:WBGene00044382 Y14H12A.2 Enriched in head mesodermal cell and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00044383 T05A7.11 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. WB:WBGene00044384 F11G11.14 Predicted to be located in membrane. WB:WBGene00044385 F59A6.10 Enriched in PVT; excretory cell; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eleven chemicals including Tunicamycin; iron oxide nanoparticle; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00044386 C27A2.7 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00044387 C27A2.8 Predicted to be involved in regulation of cholinergic synaptic transmission and sleep. WB:WBGene00044388 C27D6.11 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cellular response to glucose starvation; intracellular signal transduction; and negative regulation of TOR signaling. Predicted to be part of nucleotide-activated protein kinase complex. Is an ortholog of several human genes including TSSK1B (testis specific serine kinase 1B); TSSK2 (testis specific serine kinase 2); and TSSK3 (testis specific serine kinase 3). WB:WBGene00044389 C27D6.12 Enriched in amphid sheath cell and sensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; daf-12; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including methylmercury hydroxide; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044390 ZK177.11 Predicted to enable protein dimerization activity. WB:WBGene00044391 C25H3.15 Enriched in germline precursor cell; hypodermis; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00044392 C25H3.16 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in membrane. WB:WBGene00044393 ZK1248.20 Predicted to be located in membrane. WB:WBGene00044394 B0034.7 Enriched in germline precursor cell; hypodermis; neurons; and ventral ganglion (ant) based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and hsf-1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044395 R12C12.10 Enriched in germline precursor cell and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including methylmercury hydroxide; 1-methylnicotinamide; and stavudine based on RNA-seq and microarray studies. WB:WBGene00044396 ZK1290.14 Enriched in intestine; neurons; pm6; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by eleven chemicals including bisphenol A; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00044397 nspc-8 Enriched in neurons based on microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including fluvastatin; Deoxyglucose; and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00044398 nspc-11 Is affected by several genes including daf-16; daf-2; and clk-1 based on microarray and RNA-seq studies. Is affected by triclosan based on microarray studies. WB:WBGene00044399 F11F1.8 Enriched in AIB and DA neuron based on single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by Rifampin; allantoin; and Colistin based on RNA-seq and microarray studies. WB:WBGene00044401 Y55B1BR.6 Enriched in body wall muscle cell from MS lineage; head mesodermal cell; interneuron; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; pmk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044402 Y82E9BL.18 Enriched in several structures, including ABalpapppa; ABalpppapa; ABalpppppa; ABarapappa; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by sixteen chemicals including tryptophan; D-glucopyranose; and Cadmium Chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00044403 fbxa-219 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including bisphenol A; Zidovudine; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00044405 C29F7.8 Is affected by hda-2 and etr-1 based on RNA-seq studies. Is affected by four chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00044406 F02A9.7 Predicted to be located in membrane. WB:WBGene00044409 C45G9.14 Enriched in dopaminergic neurons; neurons; somatic gonad precursor; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including nhr-49; daf-3; and set-2 based on tiling array and RNA-seq studies. Is affected by Rifampin based on RNA-seq studies. WB:WBGene00044410 F48E8.8 Enriched in several structures, including ABalaaaala; ABalaapaaa; cholinergic neurons; excretory cell; and head neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; sek-1; and lin-39 based on RNA-seq and microarray studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00044411 R12B2.8 Predicted to be located in membrane. WB:WBGene00044412 F40H6.6 Enriched in AFD; germ line; sensory neurons; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and fog-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044413 B0205.12 Enriched in ABplpppaapa; ABprpppaapa; AFD; hypodermis; and muscle cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; aak-2; and unc-30 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; D-glucose; and stavudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: Short transmembrane mitochondrial protein 1 and Domain of unknown function (DUF4535). WB:WBGene00044414 C06A5.12 Predicted to be located in membrane. WB:WBGene00044415 C08E3.14 Is affected by several genes including dpy-21; mrg-1; and smn-1 based on tiling array and RNA-seq studies. WB:WBGene00044416 C08E3.15 Is affected by several genes including skn-1; clk-1; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044417 C08F1.11 Predicted to be located in membrane. WB:WBGene00044418 C08G5.7 Predicted to be located in membrane. WB:WBGene00044419 fbxc-17 Enriched in several structures, including ABalpppppp; ABalppppppp; ABpraaapppp; amphid neurons; and excretory gland cell based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; clk-1; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Rifampin and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domain: Protein of unknown function DUF3557. WB:WBGene00044420 C50D2.10 Enriched in Z1.p; Z4.a; germ line; intestine; and male distal tip cell based on RNA-seq studies. Is affected by several genes including daf-12; sir-2.1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including rotenone; D-glucose; and metformin based on RNA-seq studies. WB:WBGene00044421 D1007.18 Enriched in mechanosensory neurons and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by Sirolimus; antimycin; and Colistin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044423 F53F10.8 Predicted to be located in membrane. Is an ortholog of human TMEM234 (transmembrane protein 234). WB:WBGene00044424 F54D12.10 Enriched in several structures, including ABalapaaaa; ABalappapa; ABalppappa; ABarappppa; and excretory cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and alg-1 based on RNA-seq studies. Is affected by metformin and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00044425 F54D12.11 Is affected by rsr-2 based on tiling array studies. WB:WBGene00044427 F56A6.5 Predicted to enable metal ion binding activity. WB:WBGene00044428 T01D1.7 Predicted to be located in membrane. WB:WBGene00044429 T07H3.7 Enriched in DA neuron; NSM; VA neuron; and intestine based on tiling array studies. Is affected by several genes including clk-1; aak-2; and mdt-15 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044430 T23F4.5 Is affected by several genes including hpl-2; dpy-21; and smg-2 based on tiling array; RNA-seq; and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00044431 mzt-1 Enriched in several structures, including ABalapppaa; ABplaapaaa; PLM; ciliated neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and npr-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044432 W03G9.9 Enriched in hyp3 and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including eat-2; drh-3; and mir-34 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044433 W10C8.6 Predicted to be located in membrane. WB:WBGene00044434 Y18H1A.15 Predicted to be located in membrane. WB:WBGene00044435 Y20F4.8 Enriched in several structures, including ABalpapppa; ABalppappa; ABarapappa; ABarappppa; and AVK based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and clk-1 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: Family of unknown function (DUF5641) and Domain of unknown function DUF5641. WB:WBGene00044436 Y47G6A.31 Enriched in several structures, including ABalaaaala; ABalaapaaa; DB neuron; germ line; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and lin-35 based on microarray and RNA-seq studies. Is affected by eleven chemicals including hydrogen sulfide; rotenone; and Alovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Zinc finger, RING-type; Ring finger domain; and Zinc finger, RING/FYVE/PHD-type. WB:WBGene00044437 Y47G6A.32 Predicted to be located in membrane. WB:WBGene00044438 Y51F10.11 Predicted to be located in Golgi apparatus; membrane; and mitochondrion. WB:WBGene00044439 Y51H7C.15 Enriched in several structures, including ABalaaaala; ABalaaaarl; AVG; ciliated neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by five chemicals including D-glucose; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044440 adpr-1 Predicted to be involved in negative regulation of fatty acid biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Used to study obesity. Is an ortholog of human WDTC1 (WD and tetratricopeptide repeats 1). WB:WBGene00044441 Y119C1B.11 Is affected by several genes including eat-2; hpl-2; and drh-3 based on tiling array; RNA-seq; and microarray studies. Is affected by Psoralens; Sirolimus; and paraquat based on RNA-seq studies. WB:WBGene00044442 T08A9.13 Enriched in intestine; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; dpy-10; and eat-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044443 ZC21.10 Enriched in several structures, including ABalaapppa; ABalaappppa; ABalapaaaa; ABalapaapa; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Alovudine; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00044444 F09G8.10 Is affected by several genes including daf-16; daf-12; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044445 C02F5.14 Enriched in several structures, including PLM; rectal epithelial cell; rectal gland cell; somatic gonad precursor; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including 1-methylnicotinamide; nicotinic acid; and rotenone based on RNA-seq and microarray studies. WB:WBGene00044446 C06G4.6 Predicted to be located in membrane. WB:WBGene00044447 ZK688.10 Predicted to be located in membrane. WB:WBGene00044448 ZK783.6 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including hydrogen sulfide; manganese chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00044449 fipr-20 Enriched in anal depressor muscle; intestinal muscle; and rectal muscle based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; stavudine; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Fungus-induced protein. WB:WBGene00044450 fipr-18 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Tunicamycin; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Fungus-induced protein. WB:WBGene00044451 fipr-19 Is affected by several genes including rrf-3; eat-2; and tph-1 based on RNA-seq studies. Is affected by seven chemicals including Alovudine; stavudine; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Fungus-induced protein. WB:WBGene00044452 Y102E9.5 Enriched in intestine and muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on RNA-seq; microarray; and proteomic studies. Is affected by ten chemicals including rotenone; Zidovudine; and allantoin based on RNA-seq studies. WB:WBGene00044453 Y102E9.6 Enriched in intestine; neurons; and in male based on RNA-seq studies. Is affected by several genes including clk-1; csr-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: Secreted clade V protein and Secreted clade V proteins. WB:WBGene00044454 F27B3.8 Enriched in NSM and pharyngeal muscle cell based on tiling array studies. Is affected by daf-2; eat-2; and mrps-5 based on microarray studies. WB:WBGene00044455 F23F12.13 Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC22A15 (solute carrier family 22 member 15) and SVOPL (SVOP like). WB:WBGene00044457 C18H7.11 Predicted to be located in membrane. WB:WBGene00044458 K11H12.10 Predicted to be located in membrane. WB:WBGene00044459 Y55F3C.9 Predicted to be located in membrane. Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00044460 Y55F3C.10 Predicted to be located in membrane. WB:WBGene00044461 Y18H1A.14 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. WB:WBGene00044462 C44B12.9 Enriched in several structures, including GLR; body muscle cell; cholinergic neurons; germ line; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and unc-30 based on tiling array and RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00044463 W09G12.10 Predicted to be located in membrane. WB:WBGene00044464 Y77E11A.16 Predicted to be located in membrane. WB:WBGene00044466 Y48A5A.3 Predicted to be involved in mitochondrial respiratory chain complex III assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 7. Is an ortholog of human UQCC2 (ubiquinol-cytochrome c reductase complex assembly factor 2). WB:WBGene00044467 R05C11.4 Predicted to be located in membrane. WB:WBGene00044468 Y69A2AL.2 Predicted to enable calcium ion binding activity and phospholipase A2 activity. Predicted to be involved in arachidonic acid secretion; lipid catabolic process; and phospholipid metabolic process. Predicted to be located in extracellular region. WB:WBGene00044469 clec-173 Enriched in head mesodermal cell and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; microarray; and proteomic studies. Is affected by fifteen chemicals including Tunicamycin; mianserin; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00044470 C09G12.17 Enriched in several structures, including ABalappaap; ABalpapppa; ABaraapapp; ABaraapppp; and ABarapappa based on single-cell RNA-seq studies. Is affected by several genes including unc-30; csr-1; and mex-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044471 F56D6.9 Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; Tunicamycin; and indole based on RNA-seq and microarray studies. WB:WBGene00044472 dct-8 Enriched in hypodermis and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; Tunicamycin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00044473 F56D6.11 Predicted to be located in membrane. WB:WBGene00044474 F56D6.12 Predicted to be located in membrane. WB:WBGene00044475 F56D6.13 Predicted to be located in membrane. WB:WBGene00044476 F56D6.14 Predicted to be located in membrane. WB:WBGene00044477 F49F1.14 Predicted to be located in membrane. WB:WBGene00044478 K06B9.6 Enriched in several structures, including GLR; MSaaaaapa; MSpppaaa; head mesodermal cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and pgl-1 based on RNA-seq and microarray studies. Is affected by four chemicals including hydrogen sulfide; 4-bromodiphenyl ether; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00044479 F15E6.10 Enriched in dopaminergic neurons; germline precursor cell; hypodermis; interfacial epithelial cell; and pharyngeal-intestinal valve cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Ethanol; rotenone; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00044480 ZK185.4 Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00044481 ZK185.5 Predicted to enable monoatomic cation transmembrane transporter activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in membrane. WB:WBGene00044482 F29B9.12 Predicted to be located in membrane. WB:WBGene00044483 H06H21.11 Enriched in AFD; AVK; NSM; germ line; and germline precursor cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; clk-1; and npr-1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq studies. WB:WBGene00044484 hot-9 Predicted to be involved in olfactory behavior and response to odorant. Predicted to be located in axon and neuronal cell body. WB:WBGene00044485 Y54G2A.41 Enriched in head mesodermal cell and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; proteomic; and RNA-seq studies. Is affected by eleven chemicals including rotenone; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044486 Y54G2A.42 Is affected by several genes including daf-12; pgl-1; and glh-1 based on tiling array and RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00044487 Y54G2A.44 Enriched in several structures, including ABalppppaa; ABplapaaapa; ABpraaapaa; amphid sheath cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including clk-1; csr-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044488 Y54G2A.45 Predicted to be involved in lipid metabolic process. WB:WBGene00044489 pudl-1 Expressed in head neurons and hyp7 syncytium. Is predicted to encode a protein with the following domains: Up-regulated in Daf-2 and Up-Regulated in long-lived daf-2. WB:WBGene00044490 pudl-2 Expressed in hyp7 syncytium and pm5. Is predicted to encode a protein with the following domains: Up-regulated in Daf-2 and Up-Regulated in long-lived daf-2. WB:WBGene00044491 Y54G2A.48 Enriched in DA neuron; VA neuron; and body wall muscle cell based on tiling array studies. Is affected by several genes including daf-2; daf-12; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Cisplatin; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00044492 Y54G2A.49 Predicted to be located in membrane. WB:WBGene00044493 Y54G2A.50 Enriched in MSaaaaapa; germ line; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and aak-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including rotenone; D-glucose; and stavudine based on RNA-seq studies. WB:WBGene00044495 Y54G2A.40 Predicted to enable metal ion binding activity. WB:WBGene00044498 Y59E9AR.10 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray studies. Is affected by Tunicamycin and Cry5B based on microarray studies. WB:WBGene00044499 T11F8.5 Predicted to be located in membrane. WB:WBGene00044500 T19E7.6 Enriched in several structures, including excretory cell; head ganglion; neurons; posterior arcade cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00044501 C55C3.8 Predicted to enable histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. WB:WBGene00044502 C46G7.5 Enriched in ABalapppaa; GABAergic neurons; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044503 Y73B6A.6 Is affected by several genes including eat-2; clk-1; and csr-1 based on microarray and RNA-seq studies. Is affected by five chemicals including 1-methylnicotinamide; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00044504 R13A1.10 Enriched in ABplpppaaa; ABprpppaaa; AIZ; body wall muscle cell; and intestine based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube; antimycin; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box protein she-1-like and F-box domain. WB:WBGene00044505 D2024.10 Enriched in muscle cell and neurons based on RNA-seq studies. Is affected by several genes including daf-3; hpl-2; and set-2 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00044508 nsy-7 Enables sequence-specific DNA binding activity. Involved in determination of left/right asymmetry in nervous system and negative regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in amphid sheath cell; intestine; and neurons. WB:WBGene00044509 K07H8.12 Enriched in body wall muscle cell; coelomocyte; head mesodermal cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and sek-1 based on microarray and RNA-seq studies. Is affected by indole; paraquat; and resveratrol based on microarray and RNA-seq studies. WB:WBGene00044510 K07H8.11 Enriched in I6 neuron; MI neuron; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044511 clec-181 Enriched in AVK; FLP; neurons; somatic gonad precursor; and in male based on microarray and RNA-seq studies. Is affected by several genes including eat-2; clk-1; and tph-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00044512 W03F9.11 Enriched in interfacial epithelial cell and rect_D based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including hydrogen sulfide; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00044513 nlp-70 Enriched in neurons and rectal epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; multi-walled carbon nanotube; and D-glucose based on RNA-seq studies. WB:WBGene00044514 R09E12.9 Enriched in arcade cell; neuronal sheath cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by thirty-three chemicals including hydrogen sulfide; Ethanol; and tryptophan based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF4440; Domain of unknown function (DUF4440); and NTF2-like domain superfamily. WB:WBGene00044515 K10C9.9 Enriched in ASER and muscle cell based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and dpy-7 based on RNA-seq and microarray studies. Is affected by nine chemicals including tryptophan; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. WB:WBGene00044516 Y32G9A.12 Is affected by several genes including clk-1; hpl-2; and dpy-21 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044517 Y32G9A.13 Is affected by several genes including eat-2; unc-30; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including rotenone; stavudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044518 fipr-25 Enriched in cephalic sheath cell and dopaminergic neurons based on tiling array studies. Is affected by several genes including daf-2; hpl-2; and mir-34 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044519 F59A7.11 Is affected by several genes including daf-2; rsks-1; and hpl-2 based on tiling array and microarray studies. Is affected by mianserin and indole based on RNA-seq and microarray studies. WB:WBGene00044520 F59A7.12 Is affected by several genes including pgl-1; bar-1; and alg-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044521 Y5H2A.4 Enriched in body wall muscle cell; hypodermis; and neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including hydrogen sulfide; Doxycycline; and cadmium based on microarray and RNA-seq studies. WB:WBGene00044523 F37B4.14 Is affected by several genes including hpl-2; dop-1; and mir-34 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00044524 Y73C8C.12 Is affected by hpl-2 and rsr-2 based on tiling array studies. WB:WBGene00044525 Y73C8B.5 Predicted to enable calcium ion binding activity and enzyme regulator activity. WB:WBGene00044526 T28A11.22 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and RMED based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; mianserin; and bisphenol S based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Ubiquitin-like domain superfamily; Ubiquitin-like domain; and Ubiquitin family. WB:WBGene00044527 Y39H10B.2 Predicted to be located in membrane. WB:WBGene00044528 lgc-29 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00044529 irld-1 Predicted to be located in membrane. WB:WBGene00044530 F32D1.11 Enriched in PLM and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and isp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fifteen chemicals including methylmercury hydroxide; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00044531 F13A2.9 Enriched in Z1.p; Z4.a; male distal tip cell; neurons; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on tiling array and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044532 T20F10.6 No description available WB:WBGene00044533 F41F3.8 Enriched in RID; body wall muscle cell; germline precursor cell; and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00044534 H23N18.6 Predicted to be located in membrane. WB:WBGene00044535 K11D12.13 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00044536 F14F9.8 Enriched in several structures, including ABalpapaap; ABarappaap; NSM; interfacial epithelial cell; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including Tunicamycin; manganese chloride; and allantoin based on microarray and RNA-seq studies. WB:WBGene00044537 B0238.15 Predicted to be located in membrane. WB:WBGene00044538 T09D3.8 Enriched in hypodermis; neurons; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and aak-2 based on RNA-seq and microarray studies. Is affected by five chemicals including D-glucose; Cry5B; and glycine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00044539 K09H11.9 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00044541 K09H11.11 Enriched in DVC and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; Alovudine; and Sodium Chloride based on RNA-seq studies. WB:WBGene00044542 CD4.11 Predicted to be involved in protein targeting to membrane; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be part of ESCRT I complex. WB:WBGene00044543 C53A3.3 Is affected by clk-1; drh-3; and pmt-2 based on microarray and RNA-seq studies. WB:WBGene00044544 F26F12.8 Predicted to be located in membrane. WB:WBGene00044545 EGAP9.4 Enriched in NSM; excretory duct; excretory pore; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and elt-2 based on RNA-seq studies. Is affected by Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00044546 T01C4.8 Enriched in ABplppppaa; ABprppppaa; NSM; rect_D; and rectal gland cell based on tiling array and single-cell RNA-seq studies. Is affected by rsr-2 and let-60 based on tiling array and microarray studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domain: Glycoside hydrolase superfamily. WB:WBGene00044547 C13A2.12 Enriched in several structures, including ABplppaaaap; ABprppaaaap; RIB; cholinergic neurons; and dopaminergic neurons based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044548 cnc-9 Enriched in amphid sheath cell; excretory duct; and excretory pore based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by Colistin and nitroguanidine based on microarray studies. WB:WBGene00044549 clec-215 Is affected by hpl-2; dpy-21; and mir-34 based on tiling array; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; C-type lectin-like/link domain superfamily; and PAN-3 domain. WB:WBGene00044550 C50E3.15 Enriched in PLM based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray studies. Is affected by Progesterone based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily. WB:WBGene00044551 ZK105.8 Predicted to be located in membrane. WB:WBGene00044552 Y97E10AR.8 Enriched in AVK; head mesodermal cell; and in male based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and npr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Rifampin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domain: Homeobox-like domain superfamily. WB:WBGene00044553 T23B12.11 Enriched in GLR; head mesodermal cell; hypodermis; neurons; and rectal epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00044554 F41E6.15 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including rotenone; bisphenol A; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00044556 F38G1.3 Predicted to be located in membrane. WB:WBGene00044557 ZC13.10 Predicted to be located in membrane. WB:WBGene00044558 F56C3.10 Is affected by several genes including clk-1; drh-3; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00044559 ZK380.5 Enriched in several structures, including ASER; Caaaaa; GLR; epithelial cell; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Hydrolyzable Tannins; Humic Substances; and paraquat based on microarray studies. WB:WBGene00044560 C36C9.6 Predicted to be located in membrane. WB:WBGene00044561 Y75D11A.6 Is affected by rsr-2; dpy-21; and klf-1 based on tiling array and RNA-seq studies. WB:WBGene00044562 C14E2.7 Predicted to be located in membrane. WB:WBGene00044563 T26C11.8 Predicted to be located in membrane. WB:WBGene00044564 ZK813.6 Predicted to be involved in cell differentiation. WB:WBGene00044565 F53B1.9 Enriched in NSM; body wall muscle cell; and neurons based on tiling array and RNA-seq studies. Is affected by hpl-2; rsr-2; and adr-1 based on tiling array and RNA-seq studies. Is affected by hydrogen sulfide based on microarray studies. WB:WBGene00044567 C46C11.4 Predicted to be located in membrane. WB:WBGene00044568 ntc-1 Predicted to enable neurohypophyseal hormone activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Expressed in neurons and ventral nerve cord. WB:WBGene00044569 C25F6.8 Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including Sodium Chloride; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044570 T22B7.8 Predicted to enable metal ion binding activity. WB:WBGene00044571 C46F4.3 Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00044573 C15B12.9 Enriched in ABalaaaala; ABalaapaaa; neurons; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including alg-1; mex-3; and set-2 based on RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00044574 F23G4.1 Predicted to be located in plasma membrane. WB:WBGene00044575 F38B6.8 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; alg-1; and dpy-21 based on RNA-seq studies. WB:WBGene00044577 F43E12.1 No description available WB:WBGene00044578 K01A12.4 Enriched in amphid neurons; head neurons; and rectal epithelium based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including hydrogen sulfide; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00044579 C06E2.9 Enriched in SAB; tail precursor cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044580 C24A3.9 Enriched in intestine based on RNA-seq studies. Is affected by rsr-2; clk-1; and lsm-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044581 Y81B9A.4 Is affected by prg-1 and drh-3 based on tiling array and RNA-seq studies. WB:WBGene00044582 B0222.11 Enriched in neuronal sheath cell and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and aak-2 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; antimycin; and cholesterol based on RNA-seq studies. Is predicted to encode a protein with the following domain: Cystine-knot cytokine. WB:WBGene00044583 F07G6.9 Is affected by mir-34 and set-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00044584 T03G11.9 Predicted to be located in membrane. WB:WBGene00044585 C40H5.8 Is affected by several genes including daf-16; sir-2.1; and hpl-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044586 Y61A9LA.12 Enriched in AIBL; AIBR; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00044587 srz-105 Predicted to be located in membrane. WB:WBGene00044588 ZK1236.9 Enriched in ABplppppap; ABprppppap; intestine; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by allantoin; Sirolimus; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00044589 C29F5.8 Predicted to be involved in regulation of glutamate receptor signaling pathway. WB:WBGene00044602 C31B8.16 Predicted to be located in membrane. WB:WBGene00044603 acbp-7 Predicted to enable fatty-acyl-CoA binding activity. Predicted to be involved in fatty acid metabolic process. WB:WBGene00044604 T10F2.5 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in cytoplasm and nucleus. Predicted to be part of TRAPP complex. Is an ortholog of human TRAPPC2L (trafficking protein particle complex subunit 2L). WB:WBGene00044605 ttr-36 Predicted to be located in cell surface and extracellular region. WB:WBGene00044606 T07G12.14 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00044607 spp-25 Enriched in intestine; muscle cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including rotenone; procyanidin; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Saposin-like. WB:WBGene00044608 glrx-22 Predicted to enable protein-disulfide reductase activity. Predicted to be located in mitochondrion. Is an ortholog of human GLRX2 (glutaredoxin 2). WB:WBGene00044609 tbcc-1 Predicted to be involved in protein folding and tubulin complex assembly. Predicted to be located in cytoplasm. Is an ortholog of human TBCC (tubulin folding cofactor C). WB:WBGene00044610 D2092.10 Enriched in neurons and rect_D based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by clk-1 based on microarray studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00044611 T27A3.8 Predicted to be located in membrane. WB:WBGene00044612 Y57E12AR.1 Predicted to enable serine-type endopeptidase inhibitor activity. WB:WBGene00044614 C36B1.14 Predicted to enable PDZ domain binding activity and microtubule binding activity. Predicted to be involved in cytoplasmic microtubule organization. Predicted to be located in dendrite. Is an ortholog of human CRIPT (CXXC repeat containing interactor of PDZ3 domain). WB:WBGene00044615 B0252.8 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00044616 M01A12.4 Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of human PTPRR (protein tyrosine phosphatase receptor type R). WB:WBGene00044617 bus-1 Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Involved in morphogenesis of an epithelium. Located in membrane. Expressed in F cell; K cell; and U cell. WB:WBGene00044618 bus-2 Predicted to enable hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Expressed in head muscle; intestine; seam cell; and spermatheca. WB:WBGene00044619 bus-3 No description available WB:WBGene00044620 bus-4 Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be located in membrane. Expressed in intestine; pharynx; and seam cell. WB:WBGene00044621 bus-5 Expressed in hyp7 syncytium; hypodermal cell; and seam cell. Human ortholog(s) of this gene implicated in Catel Manzke syndrome. Is predicted to encode a protein with the following domains: NAD(P)-binding domain superfamily; NAD(P)-binding domain; and GDP-mannose 4,6 dehydratase. Is an ortholog of human TGDS (TDP-glucose 4,6-dehydratase). WB:WBGene00044622 bus-6 No description available WB:WBGene00044623 bus-8B Predicted to enable alpha-1,3-mannosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process. Predicted to be located in membrane. Expressed in seam cell. WB:WBGene00044624 bus-10 No description available WB:WBGene00044627 bus-14 No description available WB:WBGene00044628 bus-15 No description available WB:WBGene00044629 bus-16 No description available WB:WBGene00044630 bus-17 Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in membrane. Is an ortholog of human B3GALT1 (beta-1,3-galactosyltransferase 1). WB:WBGene00044631 bus-18 Enables acyltransferase activity. Involved in morphogenesis of an epithelium and phosphatidylinositol metabolic process. Located in endoplasmic reticulum. Expressed in several structures, including AIY; excretory gland cell; hypodermis; interfacial epithelial cell; and vulva. Is an ortholog of human LCLAT1 (lysocardiolipin acyltransferase 1). WB:WBGene00044632 Y73F8A.37 Is affected by several genes including clk-1; smg-2; and xpf-1 based on microarray and RNA-seq studies. Is affected by metformin and Sirolimus based on RNA-seq studies. WB:WBGene00044633 F54H12.7 Predicted to be located in membrane. WB:WBGene00044634 C29E4.14 Predicted to enable calcium ion binding activity. WB:WBGene00044636 B0393.9 Enriched in coelomocyte; germ line; head mesodermal cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including tryptophan; manganese chloride; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00044637 rft-1 Enables riboflavin transmembrane transporter activity. Involved in embryo development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A2 (solute carrier family 52 member 2) and SLC52A3 (solute carrier family 52 member 3). WB:WBGene00044638 F23A7.8 Enriched in several structures, including germ line; germline precursor cell; neurons; rectal gland cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; tiling array; and microarray studies. Is affected by thirteen chemicals including hydrogen sulfide; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00044639 C24H12.12 Is affected by several genes including eat-2; pgl-1; and glh-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including indole; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00044640 B0432.14 Enriched in head mesodermal cell and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq; tiling array; and microarray studies. Is affected by four chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044641 T01D1.8 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; AFD; and anterior hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044642 clec-69 Is affected by several genes including daf-16; daf-2; and dpy-10 based on RNA-seq and microarray studies. Is affected by eighteen chemicals including rotenone; D-glucose; and sesamin based on RNA-seq and microarray studies. WB:WBGene00044643 H17B01.5 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00044644 B0205.13 Enriched in several structures, including CEP; PVP; intestine; rectal gland cell; and sensory neurons based on tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on proteomic; RNA-seq; microarray; and tiling array studies. Is affected by thirty-three chemicals including hydrogen sulfide; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00044645 Y51H7BR.8 Predicted to be located in membrane. WB:WBGene00044646 B0205.14 Enriched in coelomocyte; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; rrf-3; and hsf-1 based on RNA-seq and microarray studies. Is affected by eighteen chemicals including tryptophan; methylmercury hydroxide; and Tunicamycin based on microarray and RNA-seq studies. WB:WBGene00044648 R144.13 Predicted to enable ubiquinone binding activity. Predicted to be involved in cellular respiration and ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Is an ortholog of human COQ10A (coenzyme Q10A). WB:WBGene00044649 C23H5.11 Predicted to be located in membrane. WB:WBGene00044650 Y71G10AR.4 Predicted to enable symporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC10A3 (solute carrier family 10 member 3) and SLC10A5 (solute carrier family 10 member 5). WB:WBGene00044651 egrh-3 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); bone disease (multiple); and lung disease (multiple). Is an ortholog of human EGR1 (early growth response 1). WB:WBGene00044652 apo-5 No description available WB:WBGene00044653 T13F3.9 Is affected by several genes including eat-2; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by fluoranthene based on microarray studies. WB:WBGene00044654 fbxa-85 Enriched in intestine based on tiling array studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq; tiling array; and microarray studies. Is affected by five chemicals including Tunicamycin; stavudine; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00044655 fbxa-194 Enriched in germ line based on RNA-seq studies. Is affected by several genes including eat-2; elt-2; and pgl-1 based on tiling array and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00044657 K10G4.11 No description available WB:WBGene00044658 C01G10.17 Enriched in arcade cell; male-specific anatomical entity; neurons; pharyngeal muscle cell; and pharyngeal-intestinal valve cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by sixteen chemicals including Tunicamycin; D-glucose; and bisphenol A based on microarray and RNA-seq studies. WB:WBGene00044659 fbxa-142 Enriched in AVA based on tiling array studies. Is affected by several genes including eat-2; clk-1; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box-like domain superfamily; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00044660 fbxa-87 Is affected by several genes including daf-2; glp-1; and eat-2 based on RNA-seq studies. Is affected by four chemicals including 1-methylnicotinamide; stavudine; and Sodium Chloride based on RNA-seq studies. WB:WBGene00044661 fbxa-143 Enriched in several structures, including DVA; Z1.p; arcade cell; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; elt-2; and npr-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Zidovudine; Tunicamycin; and antimycin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00044662 F26G1.9 Enriched in PLM; germline precursor cell; hypodermis; and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercury hydroxide; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00044663 F26G1.10 Enriched in PLM; head mesodermal cell; intestinal muscle; intestine; and rectal muscle based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Tunicamycin; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Transthyretin-like superfamily. WB:WBGene00044664 F59A6.11 Is affected by several genes including eat-2; sir-2.1; and sek-1 based on RNA-seq; tiling array; and microarray studies. Is affected by six chemicals including Ethanol; tryptophan; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00044665 F59A6.12 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including hydrogen sulfide; Zidovudine; and metformin based on microarray; RNA-seq; and proteomic studies. WB:WBGene00044666 F33G12.7 Predicted to be located in membrane. WB:WBGene00044667 ZK622.5 Enriched in RMD; arcade cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00044668 C18A3.11 Is affected by several genes including spn-4; alh-4; and rsr-2 based on tiling array and RNA-seq studies. Is affected by tryptophan based on microarray studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00044670 rac-3 Is affected by several genes including let-60; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by Alovudine and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044672 fbxa-4 Enriched in RIM; arc ant V; and intestine based on tiling array; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including antimycin; R24; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00044673 C07D10.6 Enriched in AVA and neurons based on tiling array and RNA-seq studies. Is affected by several genes including nhr-49; csr-1; and mex-3 based on microarray and RNA-seq studies. Is affected by mianserin and cadmium based on RNA-seq studies. WB:WBGene00044674 B0280.17 Predicted to enable mRNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. WB:WBGene00044675 fbxa-76 Enriched in AIY; intestine; mechanosensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00044676 fbxa-42 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and RIM based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00044677 ZK353.10 Predicted to be involved in cell division. Predicted to be located in membrane. WB:WBGene00044678 B0303.16 Predicted to be located in membrane. WB:WBGene00044679 K02B12.9 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; isp-1; and unc-30 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00044680 F30A10.13 Enriched in PLML; PLMR; germ line; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including manganese chloride; mianserin; and stavudine based on RNA-seq and microarray studies. WB:WBGene00044681 T24C4.8 Predicted to be located in membrane. WB:WBGene00044683 C36E6.8 Predicted to be located in membrane. WB:WBGene00044684 T08G11.2 Enriched in germ line and in male based on proteomic and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and age-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including Ethanol; methylmercuric chloride; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00044685 gla-1 No description available WB:WBGene00044686 flp-28 Enriched in neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044687 B0563.9 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by thirteen chemicals including Tunicamycin; multi-walled carbon nanotube; and iron oxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00044689 arid-1 Predicted to enable transcription cis-regulatory region binding activity. Acts upstream of or within ERAD pathway and defense response to other organism. Predicted to be located in nucleus. Predicted to be part of transcription repressor complex. Is an ortholog of human ARID4A (AT-rich interaction domain 4A). WB:WBGene00044690 M02B7.7 Enriched in several structures, including ABalppappa; ABalppppaa; ABarappppa; germ line; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including glp-1; hsf-1; and alg-1 based on microarray; RNA-seq; and proteomic studies. Is affected by five chemicals including rotenone; Rifampin; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Protein POLR1D, isoform 2-like. WB:WBGene00044691 F47C12.11 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including hpl-2; ubc-9; and dlc-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044692 fbxb-91 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; pharyngeal cell; and rect_D based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00044693 fbxb-92 Enriched in ABplpappaa; excretory duct; and excretory pore based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including indole; Alovudine; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00044694 fbxb-90 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalpapaap; AVD; and RIH based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; rotenone; and mianserin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00044695 fbxb-27 Is affected by several genes including daf-2; eat-2; and hda-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00044696 F52E1.14 Enriched in OLL; PVD; head mesodermal cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eighteen chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00044697 poml-4 Predicted to enable arylesterase activity. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); eye disease (multiple); and hematologic cancer (multiple). Is an ortholog of human PON1 (paraoxonase 1); PON2 (paraoxonase 2); and PON3 (paraoxonase 3). WB:WBGene00044698 K09F5.6 Predicted to be located in membrane. WB:WBGene00044699 nhr-286 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00044700 T08D2.9 Is affected by several genes including daf-2; pgl-1; and unc-30 based on RNA-seq studies. WB:WBGene00044701 AH9.6 Predicted to be located in membrane. WB:WBGene00044702 F46C3.4 Enriched in RID and germ line based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00044703 F46C3.5 Is affected by several genes including daf-2; let-418; and chd-3 based on RNA-seq and microarray studies. Is affected by 1-methylnicotinamide based on RNA-seq studies. WB:WBGene00044704 C18A3.12 Is affected by daf-12 and prg-1 based on tiling array and RNA-seq studies. WB:WBGene00044705 T22F3.12 Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. WB:WBGene00044706 Y26D4A.15 Is affected by dpy-21 and rrf-1 based on RNA-seq and microarray studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00044707 pals-15 Predicted to be located in membrane. WB:WBGene00044708 pals-11 Is affected by several genes including skn-1; rrf-3; and elt-2 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00044709 pals-12 Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00044710 Y26D4A.16 No description available WB:WBGene00044711 pals-10 Is affected by several genes including skn-1; elt-2; and lin-35 based on microarray and RNA-seq studies. Is affected by seven chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00044712 F22G12.8 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by bortezomib and Colistin based on RNA-seq and microarray studies. WB:WBGene00044713 ZK1225.9 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00044714 ZK1225.10 Is affected by clk-1 and sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00044716 ZK1225.12 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00044718 T20D4.20 Enriched in NSM and body wall muscle cell based on tiling array studies. Is affected by several genes including daf-16; rrf-3; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including Tunicamycin; resveratrol; and Atrazine based on microarray studies. WB:WBGene00044719 clec-172 Involved in defense response to Gram-positive bacterium. WB:WBGene00044720 metl-2 Predicted to enable tRNA (cytosine-3-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Is an ortholog of human METTL2A (methyltransferase 2A, tRNA N3-cytidine) and METTL2B (methyltransferase 2B, tRNA N3-cytidine). WB:WBGene00044722 C17H1.12 Is affected by daf-2 and ints-2 based on microarray and RNA-seq studies. WB:WBGene00044723 K11H12.11 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eighteen chemicals including D-glucopyranose; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00044724 R02E4.3 Enriched in several structures, including GABAergic neurons; PLM; carbon dioxide sensory neurons; excretory cell; and interfacial epithelial cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on tiling array; RNA-seq; and microarray studies. Is affected by twenty-six chemicals including Ethanol; 1-methylnicotinamide; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00044725 R11G1.7 Enriched in several structures, including ABalapaaaa; ABalappapa; accessory cell; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including hydrogen sulfide; 1-methylnicotinamide; and mianserin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044726 Y53F4B.43 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalapaaaa; ABalappapa; and head neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and hda-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Regulator protein PHA-1 and Regulator protein, PHA-1. WB:WBGene00044727 Y53F4B.44 Is affected by eat-2 based on microarray studies. WB:WBGene00044728 Y53F4B.45 Enriched in head mesodermal cell; muscle cell; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including 4-bromodiphenyl ether; tert-Butylhydroperoxide; and antimycin based on microarray and RNA-seq studies. WB:WBGene00044729 Y53F4B.46 Is affected by dpy-21 and flcn-1 based on RNA-seq and microarray studies. WB:WBGene00044731 eat-1 No description available WB:WBGene00044732 T03G11.10 Enriched in neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including mianserin; multi-walled carbon nanotube; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00044733 W08F4.13 Enriched in several structures, including ABalpppppp; ABplppppap; ABpraaappp; ABprppppap; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Alovudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00044734 Y19D10A.16 Predicted to enable carbohydrate binding activity and isomerase activity. Predicted to be involved in hexose metabolic process. Human ortholog(s) of this gene implicated in galactosemia. Is an ortholog of human GALM (galactose mutarotase). WB:WBGene00044735 Y19D10A.17 Enriched in muscle cell based on microarray studies. Is affected by eat-2 based on RNA-seq studies. Is affected by tetrabromobisphenol A based on microarray studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class bc (Srbc) and Serpentine type 7TM GPCR chemoreceptor Srbc. WB:WBGene00044736 gfrp-1 Predicted to enable GTP cyclohydrolase binding activity. Predicted to be involved in negative regulation of biosynthetic process. Predicted to be located in cytoplasm and nucleus. Expressed in head; hyp7 syncytium; hypodermis; and neurons. Is an ortholog of human GCHFR (GTP cyclohydrolase I feedback regulator). WB:WBGene00044737 ttr-45 Predicted to be located in cell surface and extracellular region. WB:WBGene00044738 folt-3 Predicted to enable folic acid binding activity and vitamin transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in biotin-responsive basal ganglia disease. Is an ortholog of human SLC19A3 (solute carrier family 19 member 3). WB:WBGene00044739 F54G8.6 Is affected by dpy-21 and adr-1 based on RNA-seq studies. WB:WBGene00044741 Y57G11C.52 Enriched in AVHL; AVHR; rect_D; ventral nerve cord; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including Ethanol; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00044742 Y55F3BR.10 Enriched in germ line and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; RNA-seq; and tiling array studies. Is affected by nine chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044743 crb-3 Predicted to be located in membrane. Expressed in several structures, including excretory canal; intestinal cell; rectal epithelium; somatic nervous system; and uterus. WB:WBGene00044744 F10G7.12 Enriched in XXXL; XXXR; germ line; neurons; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00044745 Y62E10A.20 Predicted to enable ribosome binding activity. Predicted to be involved in inner mitochondrial membrane organization and protein insertion into mitochondrial inner membrane from matrix. Predicted to be located in mitochondrial inner membrane. Is an ortholog of human MAIP1 (matrix AAA peptidase interacting protein 1). WB:WBGene00044746 C53H9.3 Predicted to be located in ribosome. WB:WBGene00044747 ZK1005.2 No description available WB:WBGene00044748 ZK402.6 Is affected by Testosterone based on microarray studies. WB:WBGene00044749 W01C8.8 Is affected by daf-12 and sir-2.1 based on tiling array and microarray studies. WB:WBGene00044750 Y39D8C.2 No description available WB:WBGene00044751 F14D2.16 Is affected by rsr-2 and hda-2 based on tiling array and RNA-seq studies. WB:WBGene00044752 Y73B6BL.45 Is affected by mir-34 and drh-3 based on microarray and RNA-seq studies. WB:WBGene00044753 F49H12.7 Enriched in ABalppppppa; ABpraaapppa; ASE; germ line; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hpl-2; and mir-71 based on RNA-seq; tiling array; and microarray studies. Is affected by six chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00044754 Y119C1B.12 Predicted to be located in membrane. WB:WBGene00044755 C32D5.14 Is affected by several genes including daf-12; mex-3; and nhr-86 based on tiling array and RNA-seq studies. Is affected by tryptophan based on microarray studies. WB:WBGene00044756 F58F12.4 Predicted to be located in membrane. WB:WBGene00044757 Y55F3BR.11 Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including Tunicamycin; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. WB:WBGene00044758 Y37H2A.12 Enriched in germ line and germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including rotenone; manganese chloride; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; HTH domain in Mos1 transposase; and F-box domain. WB:WBGene00044759 T06E6.15 Enriched in neurons and seam cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00044760 Y71H2AM.25 Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; cerebrovascular disease (multiple); and pycnodysostosis. Is an ortholog of human CTSK (cathepsin K) and CTSS (cathepsin S). WB:WBGene00044761 pals-19 Enriched in several structures, including dopaminergic neurons; head mesodermal cell; pharyngeal muscle cell; rect_D; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including Tunicamycin; Alovudine; and stavudine based on microarray and RNA-seq studies. WB:WBGene00044762 ZK688.11 Predicted to be located in membrane. WB:WBGene00044763 ZK688.12 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including manganese chloride; D-glucose; and levamisole based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Major sperm protein (MSP) domain; PapD-like superfamily; MSP (Major sperm protein) domain; and Immunoglobulin-like fold. WB:WBGene00044764 W01A8.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including alg-1; smg-2; and ubc-9 based on tiling array; microarray; and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00044765 C17B7.13 No description available WB:WBGene00044766 Y55F3C.11 No description available WB:WBGene00044767 T23B7.3 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00044768 M117.7 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00044769 C17E4.12 Is affected by several genes including daf-2; pgl-1; and osm-3 based on RNA-seq and microarray studies. Is affected by Colistin and triclosan based on microarray studies. WB:WBGene00044770 C53C11.5 Predicted to be located in membrane. WB:WBGene00044771 tmem-218 Involved in non-motile cilium assembly. Located in ciliary transition zone. Expressed in amphid neurons and phasmid neurons. WB:WBGene00044772 T23E7.6 Predicted to be located in membrane. WB:WBGene00044773 C08A9.10 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by fifteen chemicals including Ethanol; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Chromadorea ALT and Chromadorea ALT protein. WB:WBGene00044774 F16B3.3 Predicted to be located in membrane. WB:WBGene00044775 ZK1290.15 Is affected by several genes including daf-12; clk-1; and prg-1 based on tiling array and microarray studies. Is affected by tryptophan and cobalt chloride based on microarray studies. WB:WBGene00044776 T02B11.8 Enriched in PLML; PLMR; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including mianserin; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Granulin superfamily and Granulin. WB:WBGene00044777 T02B11.9 Predicted to be located in membrane. WB:WBGene00044778 K09C6.10 Predicted to be located in membrane. WB:WBGene00044779 T10H9.8 Enriched in dopaminergic neurons; germline precursor cell; hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: EF-hand domain pair. WB:WBGene00044780 F18E9.8 Predicted to be located in membrane. WB:WBGene00044781 Y53H1A.6 Is affected by dpy-21 and qui-1 based on RNA-seq studies. Is affected by Sirolimus and allantoin based on microarray studies. WB:WBGene00044782 F41D3.13 Is affected by daf-2; etr-1; and eat-2 based on microarray and RNA-seq studies. WB:WBGene00044783 T26H5.10 Enriched in GABAergic neurons; OLL; PVD; intestine; and ventral nerve cord based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nineteen chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00044784 F13H10.8 Predicted to be involved in sphingolipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00044786 ZK1053.7 Enriched in neurons based on RNA-seq studies. Is affected by rsr-2; dpy-21; and adr-1 based on tiling array and RNA-seq studies. WB:WBGene00044787 pals-36 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00044788 ttr-38 Predicted to be located in cell surface and extracellular region. WB:WBGene00044789 T07A9.14 Enriched in OLL; PVD; germ line; male-specific anatomical entity; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; bisphenol S; and paraquat based on RNA-seq and microarray studies. WB:WBGene00044790 clec-224 Predicted to enable carbohydrate binding activity. Predicted to be located in external side of plasma membrane. Is an ortholog of human CLEC4E (C-type lectin domain family 4 member E). WB:WBGene00044791 bnc-1 Predicted to enable metal ion binding activity. Involved in cell fate specification and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in cholinergic neurons and in male. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 16. Is an ortholog of human BNC1 (basonuclin zinc finger protein 1) and BNC2 (basonuclin zinc finger protein 2). WB:WBGene00044792 F59C6.14 Predicted to be located in membrane. WB:WBGene00044794 Y59A8B.25 Predicted to enable soluble NSF attachment protein activity and syntaxin binding activity. Predicted to be involved in intracellular protein transport. Predicted to be part of SNARE complex. Is an ortholog of human NAPG (NSF attachment protein gamma). WB:WBGene00044795 C06H5.8 Enriched in ADEshL; ADEshR; head mesodermal cell; and muscle cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00044796 W03D8.11 Enriched in hypodermis and tail hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including methylmercury hydroxide; manganese chloride; and levamisole based on RNA-seq and microarray studies. WB:WBGene00044797 F13E9.13 Predicted to be located in mitochondrion. WB:WBGene00044798 tbx-43 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance; malaria; and primary immunodeficiency disease. Is an ortholog of human TBX21 (T-box transcription factor 21). WB:WBGene00044799 ZK686.6 Enriched in DA neuron; PLML; PLMR; VA neuron; and intestine based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00044800 C56A3.9 Is affected by several genes including eat-2; dpy-7; and cnd-1 based on RNA-seq studies. Is affected by six chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00044801 ZC262.9 Predicted to be located in membrane. WB:WBGene00044802 ZC262.10 Is affected by several genes including daf-18; csr-1; and nhr-8 based on RNA-seq and microarray studies. Is affected by methylmercury hydroxide based on RNA-seq studies. Is predicted to encode a protein with the following domains: Tight junction protein, Claudin-like and Tight junction protein, claudin-like. WB:WBGene00044803 C02G6.3 Predicted to be located in membrane. WB:WBGene00044804 ZK938.8 Is affected by several genes including daf-16; smn-1; and mrps-5 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00044805 Y53C10A.15 Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in cytoskeleton. WB:WBGene00044806 T19H5.5 Is affected by hda-2 and hlh-26 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00044807 T19H5.6 Predicted to enable chitin binding activity. Predicted to be involved in carbohydrate metabolic process. Predicted to be located in membrane. WB:WBGene00044808 Y39A1A.25 Is affected by daf-16 and dlc-1 based on RNA-seq studies. WB:WBGene00044809 M04F3.6 Is affected by several genes including daf-2; dpy-10; and hsf-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Humic Substances; paraquat; and Sirolimus based on microarray studies. WB:WBGene00044810 Y37E3.19 Predicted to be located in membrane. WB:WBGene00044811 nta-1 Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). WB:WBGene00044889 T10D4.14 Predicted to be located in membrane. WB:WBGene00044891 T07C4.12 Enriched in ABplpaaaap; ABprpaaaap; PVR; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including aak-2; smg-2; and mir-34 based on RNA-seq and microarray studies. Is affected by five chemicals including mianserin; stavudine; and Rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domain: COMM domain. WB:WBGene00044892 clec-257 Enriched in muscle cell and neurons based on microarray studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on tiling array; RNA-seq; and microarray studies. Is affected by Alovudine; Atrazine; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin-like; PAN-like domain; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and PAN-3 domain. WB:WBGene00044893 mig-33 No description available WB:WBGene00044894 Y71F9AR.4 Enriched in several structures, including M cell; arcade cell; germ line; germline precursor cell; and pharyngeal-intestinal valve cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and clk-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by five chemicals including rotenone; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00044895 R06A10.5 Predicted to be located in membrane. WB:WBGene00044896 K12C11.5 Enriched in male based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and npr-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Rifampin; Sirolimus; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00044897 M01D7.9 Enriched in muscle cell based on RNA-seq studies. Is affected by several genes including eat-2; nhr-49; and csr-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00044898 let-383 Enriched in germline precursor cell; hypodermis; intestine; and somatic gonad precursor based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00044900 cnc-11 Involved in defense response to fungus and innate immune response. Predicted to be located in membrane. WB:WBGene00044901 Y41G9A.10 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and excretory system based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by fourteen chemicals including rotenone; Tunicamycin; and juglone based on RNA-seq and microarray studies. WB:WBGene00044902 Y19D10A.18 Is affected by dpy-21 based on RNA-seq studies. Is affected by tetrabromobisphenol A and dafa#1 based on microarray studies. WB:WBGene00044903 K03H1.13 Predicted to enable nucleotide binding activity and transferase activity, transferring phosphorus-containing groups. Predicted to be involved in organic substance metabolic process and primary metabolic process. Is an ortholog of human FPGT (fucose-1-phosphate guanylyltransferase). WB:WBGene00044905 T26E3.11 Is affected by several genes including daf-2; eat-2; and let-418 based on RNA-seq and microarray studies. Is affected by five chemicals including rotenone; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00044906 Y67A10A.11 Enriched in AMshL; AMshR; amphid sheath cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including tph-1; cat-2; and csr-1 based on RNA-seq studies. Is affected by Colistin based on microarray studies. Is predicted to encode a protein with the following domain: Thrombospondin type-1 (TSP1) repeat superfamily. WB:WBGene00044907 K08E7.10 Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00044908 F38A1.15 Enriched in ABplpapppa; neurons; and rect_D based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and nhr-49 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain; Concanavalin A-like lectin/glucanase domain superfamily; and PAN-3 domain. WB:WBGene00044909 C48D1.7 Enriched in AVK and in male based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by Doxycycline; paraquat; and Colistin based on RNA-seq and microarray studies. WB:WBGene00044911 H38K22.6 Predicted to be located in membrane. WB:WBGene00044912 H38K22.7 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including sir-2.1; pgl-1; and hsp-6 based on RNA-seq and microarray studies. Is affected by nine chemicals including Sodium Chloride; Cry5B; and Ag nanoparticles based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1179 and Protein of unknown function (DUF1179). WB:WBGene00044914 T11B7.6 No description available WB:WBGene00044916 F40F8.11 Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to be part of Sm-like protein family complex and ribonucleoprotein complex. WB:WBGene00044917 F40F8.12 Predicted to be located in membrane. WB:WBGene00044918 mig-27 No description available WB:WBGene00044920 F20G2.7 Enriched in AVK and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and metformin based on RNA-seq studies. WB:WBGene00044921 F53C11.9 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00044922 Y43C5A.7 Predicted to be located in membrane. WB:WBGene00044923 T27E4.10 Is affected by several genes including daf-12; lag-1; and dpy-21 based on tiling array and RNA-seq studies. WB:WBGene00044924 M106.7 Predicted to enable nucleotide binding activity. Predicted to be involved in transcription initiation at RNA polymerase III promoter. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is an ortholog of human CRCP (CGRP receptor component). WB:WBGene00044925 Y37E3.20 Is affected by several genes including set-2; ptl-1; and dlc-1 based on RNA-seq studies. WB:WBGene00044926 Y39G10AR.24 No description available WB:WBGene00044927 F32B5.9 Is affected by several genes including pgl-1; cep-1; and glh-1 based on tiling array and RNA-seq studies. WB:WBGene00044928 Y71F9AM.7 Enriched in neurons based on RNA-seq studies. Is affected by several genes including glp-1; clk-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044929 R12E2.17 Enriched in AFD based on RNA-seq studies. Is affected by daf-12; set-2; and etr-1 based on tiling array and RNA-seq studies. WB:WBGene00044930 T19B4.8 Is affected by several genes including prg-1; meg-3; and meg-4 based on RNA-seq studies. WB:WBGene00044931 Y37E3.21 Is affected by etr-1 based on RNA-seq studies. Is affected by sodium arsenite based on RNA-seq studies. WB:WBGene00044932 Y37E3.22 Enriched in AFD based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00044933 ZK484.9 Is affected by daf-2 and mys-1 based on RNA-seq studies. WB:WBGene00044934 T27A3.9 Is affected by several genes including daf-2; prg-1; and ptl-1 based on RNA-seq studies. WB:WBGene00044935 T08B2.13 Is affected by daf-12; hpl-2; and cep-1 based on tiling array and RNA-seq studies. WB:WBGene00044936 T24H7.6 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-12; hpl-2; and set-2 based on tiling array and RNA-seq studies. WB:WBGene00044937 ZK546.18 Is affected by several genes including daf-12; cep-1; and set-2 based on tiling array and RNA-seq studies. WB:WBGene00044938 C27H5.9 Is affected by several genes including daf-2; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00044939 B0412.7 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00044940 H06I04.8 Is affected by several genes including daf-12; pgl-1; and prg-1 based on tiling array and RNA-seq studies. Is affected by rotenone based on RNA-seq studies. WB:WBGene00044941 F54E7.10 Is affected by several genes including daf-12; clk-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00044942 F54E7.11 Is affected by several genes including daf-12; clk-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00044943 R151.12 Is affected by several genes including hpl-2; set-2; and swsn-1 based on tiling array and RNA-seq studies. WB:WBGene00044944 R151.13 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00044945 C07H6.10 Is affected by several genes including daf-12; clk-1; and pgl-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044946 C03B8.5 Enriched in AFD based on RNA-seq studies. Is affected by daf-12 and cep-1 based on tiling array and RNA-seq studies. WB:WBGene00044947 F32E10.10 Is affected by daf-2 based on RNA-seq studies. WB:WBGene00044948 K11H12.12 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-12; pgl-1; and glh-1 based on tiling array and RNA-seq studies. Is affected by rotenone based on RNA-seq studies. WB:WBGene00044949 Y49A10A.2 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalapapapa; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and sek-1 based on RNA-seq and microarray studies. Is affected by six chemicals including 1-methylnicotinamide; bisphenol S; and stavudine based on RNA-seq and microarray studies. WB:WBGene00044951 2RSSE.3 Is affected by several genes including daf-16; sek-1; and pgl-1 based on RNA-seq studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00044952 Y24D9A.9 Enriched in AFD and germ line based on RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and prg-1 based on RNA-seq and microarray studies. Is affected by bisphenol A and glycine based on RNA-seq studies. WB:WBGene00044953 D2096.13 Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; multi-walled carbon nanotube; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00044954 D2096.14 Is affected by several genes including daf-12; pgl-1; and cep-1 based on tiling array and RNA-seq studies. WB:WBGene00044955 K07C11.11 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00044956 K07C11.12 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00044957 C08D8.3 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00044958 ZK994.7 Enriched in neurons based on RNA-seq studies. Is affected by hpl-2 based on tiling array studies. WB:WBGene00044959 mig-34 No description available WB:WBGene00044960 fbxa-173 Is affected by several genes including clk-1; hpl-2; and dpy-21 based on microarray and RNA-seq studies. WB:WBGene00044961 F56A12.5 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; glp-1; and lag-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00044962 F28D1.13 Is affected by several genes including daf-12; pgl-1; and glh-1 based on tiling array and RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00044963 K07C5.11 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00044964 F22D6.16 Is affected by several genes including daf-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00044965 smy-6 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00044966 smy-12 No description available WB:WBGene00044967 smy-9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; clk-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00044968 K10H10.11 Is affected by hda-6 and ptl-1 based on RNA-seq studies. WB:WBGene00044969 T28D6.10 Is affected by ifo-1 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00044970 F38E11.14 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on RNA-seq studies. WB:WBGene00044971 C15H11.12 Is affected by several genes including daf-2; eat-2; and set-2 based on RNA-seq and microarray studies. WB:WBGene00044972 F35E12.11 Is affected by several genes including daf-2; alg-1; and hpl-2 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube and Cry5B based on RNA-seq and microarray studies. WB:WBGene00044973 F08G2.12 Is affected by daf-2; set-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Ethanol and resveratrol based on microarray studies. WB:WBGene00044974 C27H6.5 Enriched in AFD and neurons based on RNA-seq studies. Is affected by rsr-2; daf-2; and ptrn-1 based on RNA-seq studies. WB:WBGene00044975 F47G4.9 Is affected by hpl-2 and set-2 based on tiling array and RNA-seq studies. WB:WBGene00044976 T26H2.10 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; stavudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00044977 F56C4.4 Enriched in coelomocyte; germ line; intestine; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirteen chemicals including bisphenol S; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00044978 F58D2.3 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalaappppa; ABalapaappa; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and let-418 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Armadillo-type fold. WB:WBGene00044979 Y41E3.19 Enriched in amphid sheath cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; D-glucose; and allantoin based on microarray and RNA-seq studies. WB:WBGene00044980 B0399.3 Enriched in neurons based on RNA-seq studies. WB:WBGene00044981 D2013.11 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00044982 C01A2.8 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00044983 T04B2.9 No description available WB:WBGene00044984 C27C7.9 Is affected by blmp-1 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00044985 F37B12.5 Is affected by hlh-26 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00044986 C34E7.5 No description available WB:WBGene00044987 K07A1.17 Predicted to be located in membrane. WB:WBGene00044988 W01A8.8 Predicted to enable hormone activity. Predicted to be involved in intracellular calcium ion homeostasis. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human STC1 (stanniocalcin 1) and STC2 (stanniocalcin 2). WB:WBGene00044989 dnbp-1 Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in cataract 48. Is an ortholog of human DNMBP (dynamin binding protein). WB:WBGene00044990 T25B9.11 Enriched in AMshL; AMshR; amphid sheath cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including tryptophan; rotenone; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00044991 T25B9.12 Enriched in excretory system; intestine; and neuronal sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and hda-2 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00044992 rax-2 No description available WB:WBGene00044994 rax-4 No description available WB:WBGene00044995 Y105C5A.28 Enriched in AVK; head mesodermal cell; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and met-2 based on RNA-seq studies. Is affected by six chemicals including allantoin; Sirolimus; and metformin based on RNA-seq studies. WB:WBGene00044997 nspd-11 Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00044998 M199.9 Enriched in cephalic sheath cell based on tiling array studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including 1-methylnicotinamide; bisphenol A; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00045000 Y41E3.20 Is affected by daf-2 and camt-1 based on microarray and RNA-seq studies. WB:WBGene00045002 F44D12.12 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00045003 F38A1.16 No description available WB:WBGene00045006 R05A10.10 No description available WB:WBGene00045007 K01G12.4 No description available WB:WBGene00045009 M117.8 Is affected by clk-1 based on microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00045011 T27E7.11 No description available WB:WBGene00045012 K08F4.13 Is affected by several genes including daf-16; daf-2; and hsf-1 based on RNA-seq and microarray studies. Is affected by Amygdalin based on RNA-seq studies. WB:WBGene00045013 F08A7.1 Predicted to be located in membrane. WB:WBGene00045016 Y105C5A.30 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00045017 F36H1.13 Is affected by mrps-5 based on microarray studies. WB:WBGene00045018 Y40H7A.14 Is affected by flcn-1 based on microarray studies. WB:WBGene00045019 Y37A1B.18 Is affected by several genes including daf-16; dpy-10; and eat-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including multi-walled carbon nanotube; Quercetin; and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00045022 K04D7.7 No description available WB:WBGene00045024 C43F9.11 Enriched in amphid sensillum; arc ant V; and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including 1-methylnicotinamide; multi-walled carbon nanotube; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00045025 Y73F8A.39 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00045026 Y7A9C.10 Is affected by clk-1 based on microarray studies. WB:WBGene00045027 Y105C5A.31 Is affected by chd-3; let-418; and eat-2 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00045028 C35D6.11 No description available WB:WBGene00045029 Y57G11C.54 Is affected by clk-1 based on microarray studies. WB:WBGene00045036 K08E4.7 Enriched in NSM; germ line; hypodermis; and in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by fourteen chemicals including manganese chloride; D-glucose; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: BTB/POZ domain; MATH/TRAF domain; MATH domain; SKP1/BTB/POZ domain superfamily; and Phosphorylation site. WB:WBGene00045037 F38A1.17 Is affected by clk-1; adr-1; and daf-2 based on microarray and RNA-seq studies. WB:WBGene00045038 ule-2 Enriched in several structures, including ABaraapapp; ABaraapppp; germ line; head ganglion; and marginal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and hsf-1 based on RNA-seq; proteomic; and microarray studies. Is affected by seventeen chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00045040 C35D6.12 Is affected by flcn-1 based on microarray studies. WB:WBGene00045043 Y116A8C.48 Enriched in AFD and muscle cell based on RNA-seq studies. Is affected by several genes including clk-1; unc-30; and hpl-2 based on RNA-seq and microarray studies. Is affected by stavudine based on RNA-seq studies. WB:WBGene00045045 Y45F10B.17 Is affected by clk-1 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00045046 Y64G10A.9 Is affected by clk-1 based on microarray studies. WB:WBGene00045048 D1007.19 Enriched in intestine and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; glp-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Alovudine; Sodium Chloride; and metformin based on RNA-seq studies. WB:WBGene00045050 ZC15.10 Enriched in XXX cell; g1; head mesodermal cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eleven chemicals including Tunicamycin; multi-walled carbon nanotube; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00045051 K11H12.13 Is affected by several genes including daf-12; pgl-1; and glh-1 based on tiling array and RNA-seq studies. WB:WBGene00045052 K12C11.6 Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in copper ion transmembrane transport and intracellular copper ion homeostasis. Predicted to be located in late endosome membrane. WB:WBGene00045053 K12C11.7 Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in copper ion transmembrane transport and intracellular copper ion homeostasis. Predicted to be located in late endosome membrane. WB:WBGene00045054 T20F10.7 No description available WB:WBGene00045055 C16D9.11 Is affected by several genes including daf-2; set-2; and nhr-86 based on RNA-seq studies. WB:WBGene00045056 F13H10.9 Predicted to be located in membrane. WB:WBGene00045057 Y106G6G.7 Is affected by several genes including pgl-1; alg-1; and glh-1 based on RNA-seq studies. WB:WBGene00045058 gadr-5 Predicted to be located in membrane. Predicted to be part of Cul2-RING ubiquitin ligase complex. WB:WBGene00045059 Y45F10B.18 No description available WB:WBGene00045060 F55B11.7 Enriched in germ line and in male based on RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including sodium arsenite; D-glucose; and cholesterol based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00045061 Y57G11B.8 Is affected by several genes including daf-2; daf-12; and nhr-49 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube and paraquat based on RNA-seq studies. WB:WBGene00045062 Y38H8A.8 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and daf-18 based on RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00045063 Y37A1A.4 Enriched in several structures, including interfacial epithelial cell; male distal tip cell; mechanosensory neurons; pharyngeal cell; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including let-60; hsf-1; and sek-1 based on microarray and RNA-seq studies. Is affected by twenty chemicals including 1-methylnicotinamide; rotenone; and D-glucose based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 21 and autosomal recessive nonsyndromic deafness 104. Human RIPOR2 enables 14-3-3 protein binding activity. Is predicted to encode a protein with the following domains: FAM65, N-terminal; RIPOR family member 3; and Filopodia upregulated, FAM65. Is an ortholog of human RIPOR1 (RHO family interacting cell polarization regulator 1); RIPOR2 (RHO family interacting cell polarization regulator 2); and RIPOR3 (RIPOR family member 3). WB:WBGene00045065 Y40H7A.15 Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00045066 Y41E3.21 Enriched in DA neuron; VA neuron; and neurons based on microarray studies. Is affected by daf-16; etr-1; and tdp-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on RNA-seq studies. WB:WBGene00045067 F07C6.6 Predicted to be located in membrane. WB:WBGene00045068 C08F11.16 Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00045069 C08F11.17 Is affected by several genes including daf-2; clk-1; and npr-1 based on tiling array; microarray; and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1505) and Protein of unknown function DUF1505. WB:WBGene00045071 T03F7.8 Is affected by rsr-2 and clk-1 based on RNA-seq and microarray studies. WB:WBGene00045072 Y43F4B.11 Is affected by several genes including clk-1; pgl-1; and glh-1 based on microarray and RNA-seq studies. WB:WBGene00045073 sli-3 No description available WB:WBGene00045074 R166.7 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00045075 W04G5.12 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00045076 W04G5.13 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00045077 Y71A12B.18 Enriched in AVK; head mesodermal cell; neurons; and sensory neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including 1-methylnicotinamide; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00045078 C46C2.7 Enriched in germ line and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including bisphenol A; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00045079 rax-3 No description available WB:WBGene00045080 rax-5 No description available WB:WBGene00045081 rax-6 No description available WB:WBGene00045082 F46F11.12 Is affected by several genes including daf-12; cep-1; and hpl-2 based on tiling array and RNA-seq studies. Is affected by Tunicamycin based on RNA-seq studies. WB:WBGene00045083 C04G6.12 Is affected by clk-1 and daf-2 based on microarray and RNA-seq studies. WB:WBGene00045084 K11C4.6 Enriched in neurons based on RNA-seq studies. Is affected by daf-12 and clk-1 based on tiling array and microarray studies. WB:WBGene00045085 Y24D9A.10 Is affected by several genes including daf-16; hpl-2; and hmg-3 based on tiling array and RNA-seq studies. WB:WBGene00045086 Y43B11AR.7 Enriched in AFD based on RNA-seq studies. Is affected by several genes including skn-1; glp-1; and pgl-1 based on RNA-seq studies. Is affected by rotenone based on RNA-seq studies. WB:WBGene00045087 B0041.9 Is affected by daf-12 based on tiling array studies. WB:WBGene00045088 F48A11.7 Is affected by several genes including daf-2; daf-12; and cep-1 based on tiling array and RNA-seq studies. WB:WBGene00045089 C05H8.3 No description available WB:WBGene00045090 C27H5.10 Is affected by hpl-2 based on tiling array studies. WB:WBGene00045091 C27H5.11 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00045092 H06I04.9 Is affected by several genes including daf-12; pgl-1; and prg-1 based on tiling array and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00045093 Y23H5B.10 Enriched in NSM based on RNA-seq studies. Is affected by several genes including glp-1; cep-1; and etr-1 based on RNA-seq studies. WB:WBGene00045094 D1007.20 Is affected by several genes including daf-12; pgl-1; and cep-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00045095 mrpr-1 Enriched in NSM based on RNA-seq studies. Is affected by several genes including sir-2.1; npr-1; and cep-1 based on RNA-seq and microarray studies. Is affected by four chemicals including rotenone; multi-walled carbon nanotube; and glycine based on RNA-seq and microarray studies. Used to study cartilage-hair hypoplasia. WB:WBGene00045096 K01A6.7 Predicted to be part of collagen trimer. WB:WBGene00045097 VY10G11R.2 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on tiling array; RNA-seq; and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00045098 VY10G11R.3 Is affected by clk-1 based on microarray studies. WB:WBGene00045099 Y67A10A.13 Is affected by clk-1 based on microarray studies. WB:WBGene00045100 K03D3.14 Is affected by rsr-2; csr-1; and clk-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00045101 C35D6.13 Predicted to be located in membrane. WB:WBGene00045102 F52B11.8 Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Cholestanol; and estrogen based on RNA-seq and microarray studies. WB:WBGene00045103 T09E11.12 No description available WB:WBGene00045104 C04G2.12 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00045105 Y7A9C.11 Is affected by several genes including daf-2; eat-2; and prg-1 based on RNA-seq and microarray studies. Is affected by Colistin and triclosan based on microarray studies. WB:WBGene00045106 Y7A9C.12 Is affected by clk-1 based on microarray studies. WB:WBGene00045107 Y7A9C.13 No description available WB:WBGene00045108 H01G02.4 Enriched in NSM; germ line; and intestine based on RNA-seq; tiling array; and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; Rifampin; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00045109 smy-2 Is affected by several genes including daf-12; set-2; and unc-70 based on tiling array and RNA-seq studies. WB:WBGene00045110 K12D12.6 Enriched in AFD based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00045111 K12D12.7 Is affected by rpl-33 and rpl-5 based on RNA-seq studies. WB:WBGene00045112 K12D12.8 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00045113 Y43F4B.12 Is affected by several genes including clk-1; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00045114 W01C9.6 Is affected by several genes including clk-1; pgl-1; and cep-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00045115 K02C4.7 Is affected by clk-1; ints-2; and ints-5 based on microarray and RNA-seq studies. WB:WBGene00045116 C53D6.12 Is affected by cep-1 and sftb-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00045117 M163.12 Is affected by endu-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00045118 T04A8.17 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00045119 F08G2.13 Is affected by glp-1; lag-1; and set-2 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00045120 Y43F8C.22 Is affected by several genes including cep-1; hpl-2; and dlc-1 based on RNA-seq studies. WB:WBGene00045121 C46C2.8 Is affected by hpl-2; rsr-2; and daf-2 based on tiling array and RNA-seq studies. WB:WBGene00045122 F22B3.10 Enriched in AVK based on RNA-seq studies. Is affected by several genes including lin-4; lin-14; and fbf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by CGP37157; copper sulfate; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; and PAN-3 domain. WB:WBGene00045123 W01D2.7 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00045124 C07A9.14 Is affected by several genes including daf-2; cep-1; and set-2 based on RNA-seq studies. WB:WBGene00045125 F54C9.12 Is affected by several genes including daf-12; hpl-2; and olrn-1 based on tiling array and RNA-seq studies. WB:WBGene00045126 C14C10.8 Is affected by several genes including daf-12; pgl-1; and cep-1 based on tiling array and RNA-seq studies. WB:WBGene00045127 W03C9.9 No description available WB:WBGene00045128 Y116A8C.49 Is affected by several genes including daf-2; drh-3; and spn-4 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00045129 Y75B12B.12 Is affected by several genes including daf-2; daf-12; and clk-1 based on tiling array; RNA-seq; and microarray studies. WB:WBGene00045130 F28C6.11 Is affected by several genes including clk-1; pgl-1; and glh-1 based on microarray and RNA-seq studies. WB:WBGene00045131 T04A11.14 Is affected by several genes including daf-16; lin-4; and lin-14 based on RNA-seq and microarray studies. WB:WBGene00045132 ZK643.9 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including skn-1; prg-1; and atfs-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00045133 M163.13 Is affected by daf-2 based on RNA-seq studies. WB:WBGene00045134 K07C5.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00045136 D1046.6 Is affected by rsr-2 and cep-1 based on RNA-seq studies. WB:WBGene00045137 F56A12.6 Is affected by several genes including glp-1; daf-12; and lag-1 based on tiling array and RNA-seq studies. WB:WBGene00045138 F25H2.14 Enriched in NSM based on RNA-seq studies. Is affected by several genes including daf-12; pgl-1; and cep-1 based on tiling array; RNA-seq; and microarray studies. Is affected by Ketamine based on RNA-seq studies. WB:WBGene00045139 F01D5.12 Is affected by cep-1 and tdp-1 based on RNA-seq studies. WB:WBGene00045140 T06C12.16 Is affected by several genes including daf-2; ptl-1; and efa-6 based on RNA-seq studies. WB:WBGene00045141 Y53F4B.47 Is affected by several genes including daf-2; cep-1; and set-2 based on RNA-seq studies. WB:WBGene00045142 Y53F4B.48 Is affected by several genes including prg-1; daf-1; and daf-3 based on RNA-seq studies. WB:WBGene00045143 Y43D4A.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and hlh-26 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00045144 Y64G10A.10 Enriched in ABplapaaaa; ABprapaaaa; DA neuron; and VA neuron based on tiling array and single-cell RNA-seq studies. Is affected by several genes including eat-2; mex-1; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by Rifampin; allantoin; and Psoralens based on RNA-seq studies. WB:WBGene00045145 F10D2.13 Is affected by several genes including clk-1; cep-1; and etr-1 based on RNA-seq and microarray studies. Is affected by Tunicamycin and multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00045146 Y41E3.22 Enriched in AVE; hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; Tunicamycin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00045147 T10B9.11 Is affected by several genes including clk-1; alg-1; and dpy-21 based on microarray and RNA-seq studies. WB:WBGene00045148 C06A1.8 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-12; pgl-1; and cep-1 based on tiling array and RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00045149 W05B2.9 Is affected by several genes including daf-2; cep-1; and dpy-21 based on RNA-seq studies. WB:WBGene00045150 ZK265.10 Is affected by daf-2 and adr-1 based on RNA-seq studies. WB:WBGene00045151 F17C11.14 Is affected by several genes including daf-12; pgl-1; and prg-1 based on tiling array and RNA-seq studies. WB:WBGene00045152 C06A1.9 Is affected by several genes including daf-12; pgl-1; and cep-1 based on tiling array and RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00045153 F11A10.9 Is affected by several genes including cep-1; set-2; and dlc-1 based on RNA-seq studies. Is affected by Tunicamycin based on RNA-seq studies. WB:WBGene00045154 C10C6.8 Is affected by cep-1; daf-2; and sftb-1 based on RNA-seq and microarray studies. WB:WBGene00045155 Y116A8C.50 Is affected by several genes including daf-2; daf-12; and eat-2 based on tiling array and microarray studies. WB:WBGene00045156 T02E1.9 Is affected by several genes including clk-1; prg-1; and ptl-1 based on RNA-seq and microarray studies. WB:WBGene00045157 K02C4.8 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-12; pgl-1; and cep-1 based on tiling array and RNA-seq studies. Is affected by Ketamine based on RNA-seq studies. WB:WBGene00045158 M163.14 Is affected by hpl-2 based on tiling array studies. WB:WBGene00045159 smy-3 Is affected by several genes including pgl-1; glh-1; and car-1 based on RNA-seq studies. WB:WBGene00045160 C41C4.11 Is affected by hpl-2 and adr-1 based on tiling array and RNA-seq studies. WB:WBGene00045161 lfor-2 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. Is affected by Ethanol and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00045162 F25H2.15 Enriched in germ line and sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; prg-1; and hpl-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and bisphenol A based on RNA-seq studies. WB:WBGene00045163 Y67A10A.14 Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including skn-1; glp-1; and clk-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00045164 F59C6.15 Enriched in germ line based on RNA-seq studies. Is affected by several genes including pgl-1; prg-1; and glh-1 based on RNA-seq studies. WB:WBGene00045165 H38K22.8 Enriched in intestine based on microarray studies. Is affected by prg-1 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00045166 Y54G2A.51 No description available WB:WBGene00045167 F43A11.8 Is affected by several genes including cep-1; prg-1; and hpl-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and glycine based on RNA-seq studies. WB:WBGene00045168 srpr-1.2 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and bar-1 based on microarray and RNA-seq studies. Is affected by Tunicamycin; multi-walled carbon nanotube; and fluvastatin based on RNA-seq studies. WB:WBGene00045169 T19C4.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00045170 T19C4.12 Is affected by several genes including meg-3; etr-1; and meg-4 based on RNA-seq studies. WB:WBGene00045171 K09E9.5 Enriched in sensory neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-12; cep-1; and prg-1 based on tiling array and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00045172 K08E3.11 Is affected by clk-1 based on microarray studies. WB:WBGene00045174 Y64G10A.12 No description available WB:WBGene00045175 C10C6.9 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq studies. Is affected by five chemicals including manganese chloride; stavudine; and Rifampin based on RNA-seq studies. WB:WBGene00045176 C53B7.8 Is affected by daf-2 and mett-10 based on RNA-seq studies. WB:WBGene00045177 T21D12.14 Enriched in OLL; PVD; and hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including 1-methylnicotinamide; D-glucose; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00045178 fipr-27 Enriched in XXXL; XXXR; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; tph-1; and aak-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00045179 F01G10.11 Is affected by several genes including daf-16; dcr-1; and bar-1 based on microarray studies. Is affected by seven chemicals including Heme; Humic Substances; and copper sulfate based on microarray studies. WB:WBGene00045180 K07F5.17 Enriched in several structures, including ABalapapapa; CAN; amphid sheath cell; germ line; and head neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including antimycin; Doxycycline; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Uncharacterized protein ZC21.8. WB:WBGene00045182 W01B6.10 Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray studies. Is affected by five chemicals including resveratrol; single-walled carbon nanotube; and paraquat based on microarray studies. WB:WBGene00045183 T28C6.10 Enriched in several structures, including ABalpapppa; ABalppappa; ABalpppapa; amphid neurons; and pharyngeal cell based on tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; bisphenol S; and allantoin based on RNA-seq and microarray studies. WB:WBGene00045184 T23F6.7 Is affected by dpy-21; daf-2; and mrps-5 based on RNA-seq and microarray studies. Is affected by Colistin and triclosan based on microarray studies. WB:WBGene00045185 VY10G11R.4 No description available WB:WBGene00045188 B0284.5 Enriched in sensory neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including multi-walled carbon nanotube; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00045189 srpr-1.1 Enriched in DD neuron based on microarray studies. Is affected by several genes including lin-4; lin-14; and cep-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Tunicamycin; multi-walled carbon nanotube; and single-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00045190 R01H2.8 Predicted to be located in membrane. WB:WBGene00045191 aho-1 No description available WB:WBGene00045192 aho-3 Predicted to enable palmitoyl-(protein) hydrolase activity. Involved in associative learning and behavioral response to starvation. Located in cytoplasmic vesicle and sensory dendrite. Expressed in AIY; amphid neurons; and serotonergic neurons. Is an ortholog of human ABHD17A (abhydrolase domain containing 17A, depalmitoylase). WB:WBGene00045193 F53B2.10 Is affected by several genes including eat-2; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00045194 smy-1 Is affected by several genes including daf-2; daf-12; and jmjd-5 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00045195 F53F4.17 Enriched in neurons and ventral nerve cord based on tiling array; single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including mianserin; iron oxide nanoparticle; and allantoin based on RNA-seq and microarray studies. WB:WBGene00045197 C29F4.4 Is affected by clk-1 based on microarray studies. WB:WBGene00045198 K10D11.7 Enriched in pharyngeal cell; pharyngeal-intestinal valve; and posterior arcade cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including Tunicamycin; Zidovudine; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00045199 smy-5 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00045200 smy-4 Is affected by clk-1 based on microarray studies. WB:WBGene00045201 smy-10 Is affected by set-2 based on RNA-seq studies. WB:WBGene00045202 Y64G10A.13 Enriched in sensory neurons based on RNA-seq studies. Is affected by swsn-1; etr-1; and sams-3 based on RNA-seq studies. Is affected by nitroguanidine based on microarray studies. WB:WBGene00045203 smy-8 No description available WB:WBGene00045204 smy-11 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00045205 smy-7 No description available WB:WBGene00045207 srlf-12 Enriched in coelomocyte; neurons; and pharyngeal muscle cell based on tiling array studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including bisphenol A; procyanidin; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00045208 F13E9.15 Enriched in amphid sheath cell; hypodermis; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including Ethanol; multi-walled carbon nanotube; and bisphenol A based on RNA-seq and microarray studies. WB:WBGene00045209 F13E9.16 Enriched in GABAergic neurons; body wall muscle cell; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-2; eat-2; and alg-1 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; Cry5B; and Atrazine based on RNA-seq and microarray studies. WB:WBGene00045210 C54D2.6 Enriched in AVJL; AVJR; head mesodermal cell; neurons; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on tiling array; microarray; and RNA-seq studies. Is affected by Colistin based on microarray studies. WB:WBGene00045211 C18D11.9 Predicted to be involved in innate immune response. WB:WBGene00045212 Y110A7A.21 Predicted to be located in membrane. WB:WBGene00045215 ceh-63 Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in ganglia; head; tail; uterus; and in male. WB:WBGene00045218 K08C9.8 Is affected by several genes including eat-2; clk-1; and pqm-1 based on microarray and RNA-seq studies. Is affected by five chemicals including rotenone; multi-walled carbon nanotube; and Psoralens based on RNA-seq studies. WB:WBGene00045234 Y26D4A.17 Predicted to be located in membrane. WB:WBGene00045235 Y26D4A.18 Is affected by clk-1 based on microarray studies. WB:WBGene00045236 Y26D4A.19 Is affected by daf-2; smn-1; and camt-1 based on microarray and RNA-seq studies. WB:WBGene00045237 mrt-1 Enables 3'-5' exonuclease activity and single-stranded DNA binding activity. Involved in nucleotide-excision repair; reproduction; and telomere maintenance via telomerase. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in dyskeratosis congenita. Is an ortholog of human DCLRE1B (DNA cross-link repair 1B). WB:WBGene00045238 rpr-1 Is affected by several genes including skn-1; tph-1; and cat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Tunicamycin; paraquat; and Ketamine based on microarray and RNA-seq studies. WB:WBGene00045239 Y49E10.29 Predicted to be located in membrane. WB:WBGene00045240 seg-1 No description available WB:WBGene00045241 seg-2 No description available WB:WBGene00045242 C05B5.11 Enriched in MSpaapaa and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including tryptophan; sodium arsenite; and Alovudine based on microarray and RNA-seq studies. WB:WBGene00045243 chep-1 No description available WB:WBGene00045244 chep-2 No description available WB:WBGene00045245 ttr-34 Predicted to be located in cell surface and extracellular region. WB:WBGene00045246 C29E4.15 Predicted to be located in membrane. WB:WBGene00045247 F54H12.8 Predicted to be located in membrane. WB:WBGene00045248 ZK180.7 Predicted to be located in membrane. WB:WBGene00045249 T07A9.15 Enriched in AVE and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on RNA-seq studies. Is affected by five chemicals including rotenone; stavudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00045250 Y73B6BL.47 Predicted to be located in membrane. WB:WBGene00045251 F54F7.9 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including 1-methylnicotinamide; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00045252 Y62H9A.15 Enriched in ASER; hypodermis; intestine; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; mianserin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00045253 F46C3.6 Enriched in several structures, including ABplppaaaap; ASER; excretory cell; interfacial epithelial cell; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00045254 F33E2.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by rotenone; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00045255 nhr-146 Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00045261 H29C22.1 Enriched in cephalic sheath cell; dopaminergic neurons; germ line; hypodermis; and spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twenty-one chemicals including 1-methylnicotinamide; rotenone; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00045265 K10C2.8 Enriched in NSM and germ line based on RNA-seq and tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Ethanol; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00045268 ttr-42 Enriched in anterior spermatheca; cephalic sheath cell; germ line; and posterior spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Transthyretin-like superfamily. WB:WBGene00045269 F46G11.6 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; rectal epithelial cell; and rectum based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercury hydroxide; D-glucose; and stavudine based on RNA-seq and microarray studies. WB:WBGene00045270 C04E7.5 Enriched in PVT and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00045271 F07G6.10 Enriched in GABAergic neurons and tail precursor cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; RNA-seq; proteomic; and microarray studies. Is affected by seventeen chemicals including Ethanol; rotenone; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00045272 F59C12.4 Enriched in several structures, including ABplaapaap; ABplpappaa; germ line; head mesodermal cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including 1-methylnicotinamide; rotenone; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00045273 C08A9.11 Enriched in anterior gonadal sheath cell; germ line; and posterior gonadal sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00045274 nre-1 Used to study autism spectrum disorder. WB:WBGene00045275 F18E3.12 Enriched in PLM; carbon dioxide sensory neurons; g2; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including rotenone; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00045276 F18E3.13 Enriched in germline precursor cell; hypodermis; intestine; pharyngeal muscle cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by nineteen chemicals including rotenone; Tunicamycin; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00045277 ZK742.6 Enriched in head mesodermal cell; muscle cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including pgl-1; sod-2; and csr-1 based on RNA-seq and microarray studies. Is affected by Rifampin; allantoin; and antimycin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00045278 B0513.11 Is affected by daf-2 based on microarray studies. WB:WBGene00045279 B0513.12 Is affected by several genes including daf-16; ahr-1; and mrps-5 based on RNA-seq studies. WB:WBGene00045280 Y116A8C.51 No description available WB:WBGene00045281 Y51H4A.33 No description available WB:WBGene00045282 Y57G11C.56 Enriched in neurons based on RNA-seq studies. Is affected by hpl-2; adr-1; and hlh-26 based on tiling array and RNA-seq studies. WB:WBGene00045283 K08E4.8 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 and qui-1 based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00045285 C08F11.18 No description available WB:WBGene00045286 C08F11.19 No description available WB:WBGene00045287 C47A4.7 Enriched in neurons based on microarray studies. Is affected by ain-2 based on microarray studies. WB:WBGene00045289 fbxa-169 Enriched in ABplapaaap; ABprapaaap; G2; W cell; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and mex-3 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box domain; FTH domain; HTH domain in Mos1 transposase; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00045290 Y102A5C.37 Is affected by clk-1 based on microarray studies. WB:WBGene00045291 F23D12.10 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00045292 fbxa-179 Enriched in AVJ; Z1.p; Z4.a; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and clk-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including tryptophan; Zidovudine; and metformin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; F-box domain; FTH domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. WB:WBGene00045293 fbxa-175 Enriched in intestine based on RNA-seq studies. Is affected by several genes including hsf-1; clk-1; and npr-1 based on microarray and RNA-seq studies. Is affected by bortezomib based on RNA-seq studies. WB:WBGene00045294 H12I19.9 Is affected by clk-1 and dpy-21 based on microarray and RNA-seq studies. WB:WBGene00045295 fbxa-222 Enriched in head mesodermal cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including Tunicamycin; multi-walled carbon nanotube; and Zidovudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Mos1 transposase, HTH domain; F-box A protein FB224; HTH domain in Mos1 transposase; and F-box domain. WB:WBGene00045297 fbxc-43 Enriched in AFD; germ line; germline precursor cell; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; RNA-seq; and tiling array studies. Is affected by ten chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00045298 fbxc-12 Enriched in RID; body wall muscle cell; and mc3 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00045299 fbxc-11 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; tph-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00045300 fbxc-10 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; tph-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00045301 fbxc-9 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by nine chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00045302 fbxc-30 Enriched in ABalpppppa; ABpraaappa; and body wall muscle cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mex-3 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF3557 and Domain of unknown function (DUF3557). WB:WBGene00045303 Y27F2A.10 Predicted to be located in membrane. WB:WBGene00045304 Y27F2A.11 Predicted to be located in membrane. WB:WBGene00045305 ZC250.4 Enriched in intestine; rect_D; rect_VL; rect_VR; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by fifteen chemicals including rotenone; bisphenol S; and 4-bromodiphenyl ether based on RNA-seq and microarray studies. WB:WBGene00045306 ZC250.5 Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. WB:WBGene00045308 C37H5.14 Predicted to enable mRNA 5'-diphosphatase activity. Predicted to be involved in NAD-cap decapping; nuclear-transcribed mRNA catabolic process; and nucleic acid phosphodiester bond hydrolysis. Predicted to be located in cytosol and nucleus. WB:WBGene00045309 srg-52 Is affected by metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00045311 Y57G11C.57 Is affected by several genes including eat-2; tph-1; and cnd-1 based on microarray and RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00045313 T27E7.12 Is affected by clk-1 based on microarray studies. WB:WBGene00045314 Y39C12A.10 No description available WB:WBGene00045315 Y116A8C.52 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray studies. WB:WBGene00045316 C49F5.9 Is affected by several genes including daf-2; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00045319 M04B2.8 Is affected by several genes including daf-2; eat-2; and dpy-21 based on RNA-seq and microarray studies. Is affected by CGP37157 based on RNA-seq studies. WB:WBGene00045321 Y43D4A.10 Is affected by several genes including met-2; pqm-1; and set-2 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00045322 C09F9.7 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; clk-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by four chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies. WB:WBGene00045323 C09G9.9 Is affected by clk-1 based on microarray studies. WB:WBGene00045324 mir-787 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. WB:WBGene00045325 mir-789.1 Enriched in sensory neurons based on RNA-seq studies. Is affected by hrpr-1; unc-70; and hrpk-1 based on RNA-seq studies. Is affected by nicotine and silicon dioxide nanoparticle based on quantitative PCR and microarray studies. WB:WBGene00045326 mir-789.2 Is affected by hrpk-1 based on RNA-seq studies. Is affected by nicotine; sanguinarine; and silicon dioxide nanoparticle based on quantitative PCR; RNA-seq; and microarray studies. WB:WBGene00045327 mir-793 Expressed in ASEL; ASER; and neurons. WB:WBGene00045328 mir-794 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR and RNA-seq studies. WB:WBGene00045329 mir-795 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. WB:WBGene00045330 mir-798 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR studies. WB:WBGene00045331 F14D7.12 Enriched in arcade cell; g1; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; dpy-7; and daf-18 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including rotenone; D-glucose; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00045332 F14D7.13 Is affected by dpy-21; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00045336 R11D1.12 Enriched in neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and aak-2 based on RNA-seq and microarray studies. Is affected by six chemicals including rotenone; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00045337 M01B2.12 Predicted to be located in cytoplasm. Is an ortholog of human PHYHIP (phytanoyl-CoA 2-hydroxylase interacting protein) and PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like). WB:WBGene00045338 M01B2.13 Predicted to be located in cytoplasm. Is an ortholog of human PHYHIP (phytanoyl-CoA 2-hydroxylase interacting protein) and PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like). WB:WBGene00045339 T10H4.13 Predicted to be located in cytoplasm. Is an ortholog of human PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein like). WB:WBGene00045340 T10G3.8 Enriched in several structures, including ABalpapaap; head mesodermal cell; interfacial epithelial cell; neurons; and ventral nerve cord based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and mex-3 based on microarray and RNA-seq studies. Is affected by allantoin; Sirolimus; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00045341 mir-784 Is affected by several genes including hsf-1; eat-2; and prg-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00045342 mir-785 Is affected by several genes including eat-2; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR and RNA-seq studies. WB:WBGene00045343 mir-786 Expressed in intestinal cell. WB:WBGene00045344 Y43F8C.23 Enriched in neurons based on RNA-seq studies. Is affected by csr-1 based on RNA-seq studies. WB:WBGene00045345 Y43F8C.24 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00045346 C06H5.9 Is affected by clk-1 based on microarray studies. WB:WBGene00045347 C14A6.9 Is affected by several genes including daf-16; bar-1; and wdr-5.1 based on microarray and RNA-seq studies. Is affected by allantoin based on microarray studies. WB:WBGene00045348 C14A6.10 Enriched in head mesodermal cell and intestine based on RNA-seq studies. Is affected by several genes including daf-16; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including metformin; Cry5B; and Quercetin based on RNA-seq and microarray studies. WB:WBGene00045350 mir-788 Is affected by several genes including glp-4; prg-1; and alg-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00045351 mir-790 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and nicotine based on RNA-seq studies. WB:WBGene00045352 mir-791 Expressed in carbon dioxide sensory neurons. WB:WBGene00045353 mir-792 Expressed in head neurons. WB:WBGene00045354 mir-796 Is affected by several genes including eat-2; prg-1; and alg-5 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and sanguinarine based on RNA-seq studies. WB:WBGene00045355 D1086.17 Enriched in germ line; sperm; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by sixteen chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00045356 T03E6.9 Predicted to be located in membrane. WB:WBGene00045357 F13A7.14 Enriched in several structures, including ABalpppappp; ABaraapapp; ABaraapppp; germ line; and male distal tip cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including manganese chloride; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00045358 mir-797 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00045359 mir-799 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR studies. WB:WBGene00045360 mir-800 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine; multi-walled carbon nanotube; and graphene oxide based on quantitative PCR and RNA-seq studies. WB:WBGene00045361 clec-253 Is affected by several genes including aak-2; drh-3; and aak-1 based on RNA-seq and microarray studies. WB:WBGene00045362 F11D11.12 Is affected by several genes including daf-2; mex-3; and mex-1 based on RNA-seq and microarray studies. WB:WBGene00045363 F11D11.13 Enriched in sensory neurons based on RNA-seq studies. Is affected by Testosterone and resveratrol based on microarray studies. WB:WBGene00045364 clec-250 Enriched in NSM and neurons based on tiling array and RNA-seq studies. Is affected by several genes including aak-2; set-2; and aak-1 based on RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain; C-type lectin-like; C-type lectin-like/link domain superfamily; C-type lectin fold; and PAN-3 domain. WB:WBGene00045365 ZC449.7 Enriched in ABplapaaap; ABprapaaap; CAN; PLM; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including elt-2; pgl-1; and nhr-49 based on microarray and RNA-seq studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00045366 Y17D7C.3 Enriched in germ line; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on RNA-seq and microarray studies. Is affected by rotenone; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00045367 F17C11.15 Enriched in AFD based on RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and prg-1 based on RNA-seq and microarray studies. WB:WBGene00045368 T23G5.7 No description available WB:WBGene00045369 F26E4.14 Enriched in AFD and intestine based on RNA-seq and microarray studies. Is affected by sir-2.1 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00045370 ZK265.11 Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including prg-1; set-2; and ptl-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00045371 M163.15 Is affected by set-2 and endu-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00045372 W01D2.8 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; set-2; and etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00045373 Y46G5A.40 Is affected by several genes including clk-1; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00045374 B0393.10 Is affected by several genes including clk-1; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00045375 C17D12.8 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00045376 F25H5.9 Enriched in sensory neurons based on RNA-seq studies. Is affected by rsr-2; cep-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00045377 F19H8.6 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00045378 H04D03.5 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00045379 C45B11.6 Predicted to enable epoxide hydrolase activity. Predicted to be involved in epoxide metabolic process. Predicted to be located in endoplasmic reticulum membrane. WB:WBGene00045380 W06G6.15 Predicted to be located in membrane. WB:WBGene00045381 F28B1.9 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; tph-1; and csr-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00045382 T05E12.8 Predicted to be located in membrane. WB:WBGene00045383 sup-46 Predicted to enable mRNA binding activity. Predicted to be located in cytoplasm and nucleus. Expressed in germ cell and somatic cell. Human ortholog(s) of this gene implicated in colorectal carcinoma and leiomyoma. Is an ortholog of human HNRNPM (heterogeneous nuclear ribonucleoprotein M) and MYEF2 (myelin expression factor 2). WB:WBGene00045385 lgc-24 Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. WB:WBGene00045386 nlp-76 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00045387 K09H9.8 Predicted to be located in membrane. WB:WBGene00045388 lfor-1 Enriched in PDB based on single-cell RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00045389 Y38F1A.11 No description available WB:WBGene00045390 spig-7 Enriched in PLM; amphid sheath cell; carbon dioxide sensory neurons; enteric muscle; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00045391 F52D4.1 Is affected by several genes including glp-1; pgl-1; and cep-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube; Tunicamycin; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00045392 F26D11.12 Enriched in PLM; body wall muscle cell; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00045393 F26D11.13 Enriched in body wall muscle cell; coelomocyte; intestine; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Rifampin; Sirolimus; and allantoin based on RNA-seq and microarray studies. WB:WBGene00045394 ZK813.7 Enriched in anterior spermatheca; cephalic sheath cell; dopaminergic neurons; hypodermis; and posterior spermatheca based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and dpy-10 based on RNA-seq; tiling array; microarray; and proteomic studies. Is affected by eleven chemicals including Ethanol; rotenone; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00045395 F09F9.5 Predicted to be located in membrane. WB:WBGene00045396 ZC334.12 Enriched in XXX cell and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. WB:WBGene00045397 Y54G2A.52 Predicted to be located in membrane. WB:WBGene00045398 Y71F9AM.8 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-2; alg-1; and drh-3 based on microarray and RNA-seq studies. Is affected by Ethanol; 2; and 4-dinitroanisole based on RNA-seq and microarray studies. WB:WBGene00045399 Y47G6A.33 Enriched in hypodermis based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by seventeen chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq; microarray; and proteomic studies. WB:WBGene00045400 C54D10.13 Enriched in intestine; mechanosensory neurons; pharyngeal muscle cell; rectal gland cell; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by four chemicals including stavudine; Sodium Chloride; and Cry5B based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00045401 eol-1 Predicted to enable 5'-3' exonuclease activity; mRNA 5'-diphosphatase activity; and mRNA binding activity. Involved in regulation of olfactory learning. Predicted to be located in cytosol and nucleus. Expressed in AVF; oxygen sensory neurons; and reproductive system. WB:WBGene00045402 Y75B12B.13 Is affected by several genes including csr-1; hpl-2; and dpy-21 based on tiling array and RNA-seq studies. WB:WBGene00045403 K10H10.12 Predicted to be located in membrane. WB:WBGene00045404 C06C3.11 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and isp-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00045405 D1086.18 Enriched in anterior arcade cell and posterior arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq; tiling array; and microarray studies. Is affected by twelve chemicals including sodium arsenite; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00045406 D1086.19 Enriched in PVP; germ line; hypodermis; and pharyngeal muscle cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including mianserin; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00045407 T07D4.5 Enriched in several structures, including ABalpppppa; ABplapaaaa; ABpraaappa; AFD; and germ line based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and npr-1 based on microarray; RNA-seq; and proteomic studies. Is affected by nine chemicals including rotenone; stavudine; and allantoin based on RNA-seq and microarray studies. Is an ortholog of human PDRG1 (p53 and DNA damage regulated 1). WB:WBGene00045408 F31E9.8 Enriched in neurons based on microarray studies. Is affected by clk-1; mut-2; and rrf-2 based on microarray studies. Is affected by cadmium and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00045410 E01G4.7 Enriched in body wall muscle cell; head mesodermal cell; hypodermis; neurons; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including rrf-3; clk-1; and sek-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including rotenone; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00045411 C25F9.11 Enriched in several structures, including ABarppaapp; ABarpppapp; g1; head mesodermal cell; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; RNA-seq; and microarray studies. Is affected by twenty-two chemicals including Ethanol; Nitric Oxide; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00045412 C25F9.12 Enriched in DVC; head mesodermal cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and npr-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Sodium Chloride; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00045413 C25F9.13 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00045414 T19H5.7 Enriched in AVK and dopaminergic neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including stavudine; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00045415 Y43F8B.15 Enriched in intestine based on RNA-seq studies. Is affected by several genes including skn-1; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Tunicamycin; tert-Butylhydroperoxide; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: SNF2-like, N-terminal domain superfamily. WB:WBGene00045416 Y37H2A.14 Predicted to be located in membrane. WB:WBGene00045417 Y37H2A.13 Enriched in AVA based on tiling array studies. Is affected by several genes including daf-16; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twenty-three chemicals including 1-methylnicotinamide; rotenone; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00045418 F15B9.10 Predicted to be located in membrane. Predicted to be part of acetylcholine-gated channel complex. WB:WBGene00045419 lsy-12 Predicted to enable histone H4K16 acetyltransferase activity and transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Predicted to be part of MSL complex. WB:WBGene00045427 lsy-21 No description available WB:WBGene00045428 lsy-26 No description available WB:WBGene00045429 lsy-25 No description available WB:WBGene00045431 lsy-19 No description available WB:WBGene00045432 lsy-20 No description available WB:WBGene00045433 F49D11.10 Predicted to enable RNA binding activity. Predicted to be involved in positive regulation of rRNA processing and positive regulation of transcription by RNA polymerase I. Predicted to be located in nucleolus. Is an ortholog of human WDR75 (WD repeat domain 75). WB:WBGene00045434 Y95D11A.3 Enriched in several structures, including ABalappaap; ABalppappa; ABalppppaa; ABalpppppa; and germ line based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; sir-2.1; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including manganese chloride; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00045455 F26G1.11 Predicted to be located in cell surface and extracellular region. WB:WBGene00045456 C10A4.9 Predicted to be located in membrane. WB:WBGene00045457 F33H12.7 Enriched in dopaminergic neurons; head mesodermal cell; intestine; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on tiling array; RNA-seq; and microarray studies. Is affected by thirty chemicals including tryptophan; methylmercury hydroxide; and 1-methylnicotinamide based on microarray and RNA-seq studies. WB:WBGene00045458 F17B5.8 Enriched in OLL; PVD; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on proteomic; tiling array; RNA-seq; and microarray studies. Is affected by seventeen chemicals including tryptophan; Tunicamycin; and sodium arsenite based on microarray and RNA-seq studies. WB:WBGene00045459 Y59A8B.26 Enriched in muscle cell based on microarray studies. Is affected by dpy-21; daf-2; and hda-2 based on RNA-seq and microarray studies. Is affected by adsorbable organic bromine compound; Sirolimus; and allantoin based on microarray studies. WB:WBGene00045460 C15C8.8 Enriched in germline precursor cell and hypodermis based on tiling array and single-cell RNA-seq studies. Is affected by several genes including clk-1; dpy-7; and daf-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; stavudine; and Zidovudine based on microarray and RNA-seq studies. WB:WBGene00045461 C25F9.14 Enriched in ASER; head mesodermal cell; intestine; and sensory neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; bisphenol A; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00045462 such-2 No description available WB:WBGene00045463 such-3 No description available WB:WBGene00045464 such-4 No description available WB:WBGene00045465 such-5 No description available WB:WBGene00045466 such-6 No description available WB:WBGene00045467 such-7 No description available WB:WBGene00045468 F08A8.8 Predicted to be located in membrane. WB:WBGene00045473 F30A10.14 Enriched in NSM; cephalic sheath cell; dopaminergic neurons; and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by thirteen chemicals including Ethanol; Tunicamycin; and stavudine based on RNA-seq and microarray studies. WB:WBGene00045474 C49G9.2 Predicted to be located in membrane. WB:WBGene00045475 T07A5.7 Enriched in ABplpapppa; hypodermis; sensory neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by six chemicals including Rifampin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00045479 C44E4.8 No description available WB:WBGene00045480 F14F3.5 Enriched in germ line; hypodermis; intestine; and neurons based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; csr-1; and mex-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; allantoin; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00045481 M153.5 Enriched in arcade cell and corpus based on single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including stavudine; Zidovudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00045482 T03F6.9 Predicted to be located in membrane. WB:WBGene00045483 oxy-5 Predicted to contribute to oxoglutarate dehydrogenase (succinyl-transferring) activity. Predicted to be involved in 2-oxoglutarate metabolic process. Predicted to be part of mitochondrial oxoglutarate dehydrogenase complex. Expressed in chemosensory neurons; head neurons; intestine; pharynx; and tail neurons. WB:WBGene00045484 F34D10.9 Enriched in several structures, including MSpaapaa; Z1.p; Z4.a; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fifteen chemicals including manganese chloride; mianserin; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00045486 K05F6.12 Predicted to be located in membrane. WB:WBGene00045487 C08E8.7 Is affected by five chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00045488 F57B1.9 Predicted to be located in membrane. WB:WBGene00045490 F14D7.14 Is affected by several genes including daf-16; eat-2; and pqm-1 based on RNA-seq and microarray studies. Is affected by tryptophan and nitroguanidine based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF4473 and Domain of unknown function (DUF4473). WB:WBGene00045491 F14D7.15 No description available WB:WBGene00045492 ZK218.14 Is affected by smn-1 based on RNA-seq studies. WB:WBGene00045493 F55G7.4 Enriched in AFD; GABAergic neurons; and NSM based on tiling array and RNA-seq studies. Is affected by several genes including clk-1; egl-9; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by bortezomib based on RNA-seq studies. WB:WBGene00045494 ZK662.6 Enriched in NSM and rectal gland cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00045495 F11C1.7 Predicted to be involved in mitochondrial fission; positive regulation of mitochondrial fission; and positive regulation of protein targeting to membrane. Predicted to be located in mitochondrial outer membrane and peroxisome. WB:WBGene00045496 C08E8.8 Is affected by dpy-21 and adr-1 based on RNA-seq studies. WB:WBGene00045497 K03A11.6 Predicted to be located in membrane. WB:WBGene00045498 F56F4.8 Predicted to be located in membrane. WB:WBGene00045500 T05E12.9 Enriched in neurons; pm8; rect_D; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including clk-1; pgl-1; and alg-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00045501 Y6G8.8 Is affected by several genes including daf-2; eat-2; and dpy-21 based on RNA-seq and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00045502 F49H6.14 Is affected by smn-1 and qui-1 based on RNA-seq studies. WB:WBGene00045503 mev-5 No description available WB:WBGene00045504 mev-6 No description available WB:WBGene00045505 mev-7 No description available WB:WBGene00045506 F57G4.10 Is affected by adr-1; meg-3; and meg-4 based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00045507 F10A3.17 Enriched in several structures, including ABalapapapa; ABalapppapa; ABplpaaappa; ABprpaaappa; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including D-glucopyranose; stavudine; and Sodium Chloride based on RNA-seq and proteomic studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00045508 D1081.10 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by four chemicals including antimycin; cholesterol; and Doxycycline based on RNA-seq studies. WB:WBGene00045509 T07D10.8 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00045510 F11A5.17 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-12; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by cobalt chloride and CGP37157 based on microarray and RNA-seq studies. WB:WBGene00045511 F11A5.18 Enriched in AFD; germ line; intestine; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00045512 Y60A3A.27 No description available WB:WBGene00045513 F14H3.14 Enriched in NSM; arcade cell; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including elt-2; clk-1; and pry-1 based on microarray and RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00045514 ZK1037.12 Is affected by etr-1 and qui-1 based on RNA-seq studies. WB:WBGene00045515 nhr-291 Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in DNA-templated transcription and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00045516 F43D2.7 Predicted to be located in membrane. WB:WBGene00045517 R11D1.13 Enriched in amphid sheath cell; dopaminergic neurons; intestine; and sensory neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; elt-2; and prg-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00045518 21ur-5153 No description available WB:WBGene00045519 21ur-4348 No description available WB:WBGene00045520 21ur-3279 No description available WB:WBGene00045521 21ur-4491 No description available WB:WBGene00045522 21ur-1293 No description available WB:WBGene00045523 21ur-4900 No description available WB:WBGene00045524 21ur-2872 No description available WB:WBGene00045525 21ur-4886 No description available WB:WBGene00045526 21ur-3726 No description available WB:WBGene00045527 21ur-3449 No description available WB:WBGene00045528 21ur-4318 No description available WB:WBGene00045529 21ur-3987 Enriched in neurons based on RNA-seq studies. WB:WBGene00045530 21ur-770 No description available WB:WBGene00045531 21ur-3262 No description available WB:WBGene00045532 21ur-116 Enriched in neurons based on RNA-seq studies. WB:WBGene00045533 21ur-338 No description available WB:WBGene00045534 21ur-248 No description available WB:WBGene00045535 21ur-2337 No description available WB:WBGene00045536 21ur-2148 No description available WB:WBGene00045537 21ur-3280 No description available WB:WBGene00045538 21ur-783 Enriched in neurons based on RNA-seq studies. WB:WBGene00045539 21ur-2502 No description available WB:WBGene00045540 21ur-2533 No description available WB:WBGene00045541 21ur-2515 No description available WB:WBGene00045542 21ur-194 No description available WB:WBGene00045543 21ur-1754 No description available WB:WBGene00045544 21ur-3162 No description available WB:WBGene00045545 21ur-4859 No description available WB:WBGene00045546 21ur-3313 No description available WB:WBGene00045547 21ur-2522 No description available WB:WBGene00045548 21ur-2768 No description available WB:WBGene00045549 21ur-4660 No description available WB:WBGene00045550 21ur-380 No description available WB:WBGene00045551 21ur-127 No description available WB:WBGene00045552 21ur-3009 No description available WB:WBGene00045553 21ur-4396 No description available WB:WBGene00045554 21ur-3929 No description available WB:WBGene00045555 21ur-4158 No description available WB:WBGene00045556 21ur-972 No description available WB:WBGene00045557 21ur-4509 No description available WB:WBGene00045558 21ur-4358 No description available WB:WBGene00045559 21ur-4032 No description available WB:WBGene00045560 21ur-3396 No description available WB:WBGene00045561 21ur-4184 No description available WB:WBGene00045562 21ur-231 No description available WB:WBGene00045563 21ur-4606 No description available WB:WBGene00045564 21ur-4026 No description available WB:WBGene00045565 21ur-1557 No description available WB:WBGene00045566 21ur-4925 No description available WB:WBGene00045567 21ur-4269 No description available WB:WBGene00045568 21ur-3115 No description available WB:WBGene00045569 21ur-4858 No description available WB:WBGene00045570 21ur-422 No description available WB:WBGene00045571 21ur-3283 No description available WB:WBGene00045572 21ur-66 No description available WB:WBGene00045573 21ur-3960 No description available WB:WBGene00045574 21ur-3455 No description available WB:WBGene00045575 21ur-3399 No description available WB:WBGene00045576 21ur-1907 No description available WB:WBGene00045577 21ur-341 No description available WB:WBGene00045578 21ur-4400 No description available WB:WBGene00045579 21ur-213 No description available WB:WBGene00045580 21ur-3922 No description available WB:WBGene00045581 21ur-3683 No description available WB:WBGene00045582 21ur-3176 No description available WB:WBGene00045583 21ur-4174 No description available WB:WBGene00045584 21ur-4213 No description available WB:WBGene00045585 21ur-687 No description available WB:WBGene00045586 21ur-5133 No description available WB:WBGene00045587 21ur-4538 No description available WB:WBGene00045588 21ur-4731 No description available WB:WBGene00045589 21ur-1571 No description available WB:WBGene00045590 21ur-5440 No description available WB:WBGene00045591 21ur-3641 No description available WB:WBGene00045592 21ur-4673 No description available WB:WBGene00045593 21ur-2000 No description available WB:WBGene00045594 21ur-2563 No description available WB:WBGene00045595 21ur-676 No description available WB:WBGene00045596 21ur-5434 No description available WB:WBGene00045597 21ur-2918 No description available WB:WBGene00045598 21ur-3144 No description available WB:WBGene00045599 21ur-3790 No description available WB:WBGene00045600 21ur-3069 No description available WB:WBGene00045601 21ur-1104 No description available WB:WBGene00045602 21ur-4930 Enriched in neurons based on RNA-seq studies. WB:WBGene00045603 21ur-5393 No description available WB:WBGene00045604 21ur-4121 No description available WB:WBGene00045605 21ur-1446 No description available WB:WBGene00045606 21ur-4963 No description available WB:WBGene00045607 21ur-3239 No description available WB:WBGene00045608 21ur-4548 No description available WB:WBGene00045609 21ur-2932 No description available WB:WBGene00045610 21ur-1584 No description available WB:WBGene00045611 21ur-620 No description available WB:WBGene00045612 21ur-5367 No description available WB:WBGene00045613 21ur-2568 Is affected by daf-2 based on microarray studies. WB:WBGene00045614 21ur-2293 No description available WB:WBGene00045615 21ur-310 No description available WB:WBGene00045616 21ur-344 No description available WB:WBGene00045617 21ur-5229 Enriched in neurons based on RNA-seq studies. WB:WBGene00045618 21ur-3525 No description available WB:WBGene00045619 21ur-5354 No description available WB:WBGene00045620 21ur-2363 No description available WB:WBGene00045621 21ur-5452 No description available WB:WBGene00045622 21ur-2954 No description available WB:WBGene00045623 21ur-3951 No description available WB:WBGene00045624 21ur-3736 No description available WB:WBGene00045625 21ur-419 No description available WB:WBGene00045626 21ur-5135 No description available WB:WBGene00045627 21ur-4966 No description available WB:WBGene00045628 21ur-3440 No description available WB:WBGene00045629 21ur-2914 No description available WB:WBGene00045630 21ur-2195 No description available WB:WBGene00045631 21ur-4580 No description available WB:WBGene00045632 21ur-2136 Enriched in neurons based on RNA-seq studies. WB:WBGene00045633 21ur-5345 No description available WB:WBGene00045634 21ur-3163 No description available WB:WBGene00045635 21ur-98 No description available WB:WBGene00045636 21ur-629 No description available WB:WBGene00045637 21ur-3513 Enriched in neurons based on RNA-seq studies. WB:WBGene00045638 21ur-4117 No description available WB:WBGene00045639 21ur-1324 No description available WB:WBGene00045640 21ur-2876 Enriched in neurons based on RNA-seq studies. WB:WBGene00045641 21ur-4617 No description available WB:WBGene00045642 21ur-3810 No description available WB:WBGene00045643 21ur-2772 No description available WB:WBGene00045644 21ur-3853 No description available WB:WBGene00045645 21ur-1572 No description available WB:WBGene00045646 21ur-4784 No description available WB:WBGene00045647 21ur-101 No description available WB:WBGene00045648 21ur-4235 No description available WB:WBGene00045649 21ur-198 No description available WB:WBGene00045650 21ur-2547 No description available WB:WBGene00045651 21ur-1325 No description available WB:WBGene00045652 21ur-378 No description available WB:WBGene00045653 21ur-1257 No description available WB:WBGene00045654 21ur-3621 No description available WB:WBGene00045655 21ur-2179 Enriched in neurons based on RNA-seq studies. WB:WBGene00045656 21ur-2373 No description available WB:WBGene00045657 21ur-4637 No description available WB:WBGene00045658 21ur-5357 No description available WB:WBGene00045659 21ur-1723 No description available WB:WBGene00045660 21ur-5403 No description available WB:WBGene00045661 21ur-780 No description available WB:WBGene00045662 21ur-4553 No description available WB:WBGene00045663 21ur-5087 No description available WB:WBGene00045664 21ur-553 No description available WB:WBGene00045665 21ur-3191 No description available WB:WBGene00045666 21ur-3306 No description available WB:WBGene00045667 21ur-22 No description available WB:WBGene00045668 21ur-1242 No description available WB:WBGene00045669 21ur-1303 No description available WB:WBGene00045670 21ur-2441 No description available WB:WBGene00045671 21ur-1935 No description available WB:WBGene00045672 21ur-2786 No description available WB:WBGene00045673 21ur-3453 No description available WB:WBGene00045674 21ur-4693 No description available WB:WBGene00045675 21ur-2281 No description available WB:WBGene00045676 21ur-2712 No description available WB:WBGene00045677 21ur-5214 No description available WB:WBGene00045678 21ur-1078 Enriched in neurons based on RNA-seq studies. WB:WBGene00045679 21ur-3510 No description available WB:WBGene00045680 21ur-4163 No description available WB:WBGene00045681 21ur-5291 No description available WB:WBGene00045682 21ur-527 No description available WB:WBGene00045683 21ur-5312 No description available WB:WBGene00045684 21ur-5385 No description available WB:WBGene00045685 21ur-1986 No description available WB:WBGene00045686 21ur-3553 No description available WB:WBGene00045687 21ur-1049 No description available WB:WBGene00045688 21ur-4041 No description available WB:WBGene00045689 21ur-3409 No description available WB:WBGene00045690 21ur-5085 No description available WB:WBGene00045691 21ur-4812 No description available WB:WBGene00045692 21ur-946 No description available WB:WBGene00045693 21ur-2392 No description available WB:WBGene00045694 21ur-5223 Enriched in neurons based on RNA-seq studies. WB:WBGene00045695 21ur-4519 No description available WB:WBGene00045696 21ur-2704 No description available WB:WBGene00045697 21ur-481 No description available WB:WBGene00045698 21ur-5244 No description available WB:WBGene00045699 21ur-5080 No description available WB:WBGene00045700 21ur-1137 No description available WB:WBGene00045701 21ur-1580 No description available WB:WBGene00045702 21ur-1740 No description available WB:WBGene00045703 21ur-457 No description available WB:WBGene00045704 21ur-3053 No description available WB:WBGene00045705 21ur-3074 No description available WB:WBGene00045706 21ur-163 No description available WB:WBGene00045707 21ur-1530 No description available WB:WBGene00045708 21ur-3591 No description available WB:WBGene00045709 21ur-5427 No description available WB:WBGene00045710 21ur-2758 No description available WB:WBGene00045711 21ur-2189 No description available WB:WBGene00045712 21ur-877 No description available WB:WBGene00045713 21ur-2188 No description available WB:WBGene00045714 21ur-895 No description available WB:WBGene00045715 21ur-764 No description available WB:WBGene00045716 21ur-2080 No description available WB:WBGene00045717 21ur-3347 No description available WB:WBGene00045718 21ur-1995 No description available WB:WBGene00045719 21ur-927 No description available WB:WBGene00045720 21ur-1318 No description available WB:WBGene00045721 21ur-1126 No description available WB:WBGene00045722 21ur-4997 No description available WB:WBGene00045723 21ur-368 No description available WB:WBGene00045724 21ur-1377 No description available WB:WBGene00045725 21ur-4839 No description available WB:WBGene00045726 21ur-4151 No description available WB:WBGene00045727 21ur-719 No description available WB:WBGene00045728 21ur-2397 No description available WB:WBGene00045729 21ur-4447 Enriched in neurons based on RNA-seq studies. WB:WBGene00045730 21ur-1475 No description available WB:WBGene00045731 21ur-2329 No description available WB:WBGene00045732 21ur-4317 No description available WB:WBGene00045733 21ur-4254 No description available WB:WBGene00045734 21ur-3918 No description available WB:WBGene00045735 21ur-3996 No description available WB:WBGene00045736 21ur-1612 Enriched in neurons based on RNA-seq studies. WB:WBGene00045737 21ur-3619 No description available WB:WBGene00045738 21ur-4550 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00045739 21ur-5063 No description available WB:WBGene00045740 21ur-4575 No description available WB:WBGene00045741 21ur-157 No description available WB:WBGene00045743 21ur-5073 No description available WB:WBGene00045744 21ur-26 No description available WB:WBGene00045745 21ur-805 No description available WB:WBGene00045746 21ur-1219 No description available WB:WBGene00045747 21ur-4706 No description available WB:WBGene00045748 21ur-4832 No description available WB:WBGene00045749 21ur-2613 No description available WB:WBGene00045750 21ur-3704 No description available WB:WBGene00045751 21ur-2649 No description available WB:WBGene00045752 21ur-909 No description available WB:WBGene00045753 21ur-2356 Enriched in neurons based on RNA-seq studies. WB:WBGene00045754 21ur-3041 No description available WB:WBGene00045755 21ur-506 No description available WB:WBGene00045756 21ur-4821 No description available WB:WBGene00045757 21ur-4437 No description available WB:WBGene00045758 21ur-133 Enriched in neurons based on RNA-seq studies. WB:WBGene00045759 21ur-5218 No description available WB:WBGene00045760 21ur-4478 No description available WB:WBGene00045761 21ur-3127 Enriched in neurons based on RNA-seq studies. WB:WBGene00045762 21ur-1620 No description available WB:WBGene00045763 21ur-3601 No description available WB:WBGene00045764 21ur-2085 No description available WB:WBGene00045765 21ur-4567 No description available WB:WBGene00045766 21ur-279 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00045767 21ur-2961 No description available WB:WBGene00045768 21ur-5176 No description available WB:WBGene00045769 21ur-1922 No description available WB:WBGene00045770 21ur-5265 No description available WB:WBGene00045771 21ur-237 No description available WB:WBGene00045772 21ur-4898 No description available WB:WBGene00045773 21ur-5304 No description available WB:WBGene00045774 21ur-4765 No description available WB:WBGene00045775 21ur-710 No description available WB:WBGene00045776 21ur-3475 No description available WB:WBGene00045777 21ur-3137 No description available WB:WBGene00045778 21ur-1912 No description available WB:WBGene00045779 21ur-3112 No description available WB:WBGene00045780 21ur-1878 No description available WB:WBGene00045781 21ur-2913 No description available WB:WBGene00045782 21ur-4300 No description available WB:WBGene00045783 21ur-447 No description available WB:WBGene00045784 21ur-1 No description available WB:WBGene00045785 21ur-520 No description available WB:WBGene00045786 21ur-1018 No description available WB:WBGene00045787 21ur-3818 No description available WB:WBGene00045788 21ur-3836 No description available WB:WBGene00045789 21ur-5257 No description available WB:WBGene00045790 21ur-4773 No description available WB:WBGene00045791 21ur-1977 No description available WB:WBGene00045792 21ur-1072 No description available WB:WBGene00045793 21ur-3911 No description available WB:WBGene00045794 21ur-1550 No description available WB:WBGene00045795 21ur-289 No description available WB:WBGene00045796 21ur-3106 Enriched in neurons based on RNA-seq studies. WB:WBGene00045797 21ur-2624 Is affected by several genes including hsp-6; hpl-2; and numr-1 based on RNA-seq studies. WB:WBGene00045798 21ur-5413 No description available WB:WBGene00045799 21ur-2826 No description available WB:WBGene00045800 21ur-986 No description available WB:WBGene00045801 21ur-1539 No description available WB:WBGene00045802 21ur-1687 No description available WB:WBGene00045803 21ur-1769 No description available WB:WBGene00045804 21ur-1354 No description available WB:WBGene00045805 21ur-3767 No description available WB:WBGene00045806 21ur-1413 No description available WB:WBGene00045807 21ur-2250 No description available WB:WBGene00045808 21ur-1627 No description available WB:WBGene00045809 21ur-630 No description available WB:WBGene00045810 21ur-3054 No description available WB:WBGene00045811 21ur-1502 No description available WB:WBGene00045812 21ur-3808 No description available WB:WBGene00045813 21ur-3942 No description available WB:WBGene00045814 21ur-5079 No description available WB:WBGene00045815 21ur-1284 No description available WB:WBGene00045816 21ur-73 No description available WB:WBGene00045817 21ur-4793 No description available WB:WBGene00045818 21ur-3584 No description available WB:WBGene00045819 21ur-5261 No description available WB:WBGene00045820 21ur-2113 No description available WB:WBGene00045821 21ur-3060 No description available WB:WBGene00045822 21ur-4192 No description available WB:WBGene00045823 21ur-1895 No description available WB:WBGene00045824 21ur-4351 No description available WB:WBGene00045825 21ur-2587 No description available WB:WBGene00045826 21ur-1680 No description available WB:WBGene00045827 21ur-1481 No description available WB:WBGene00045828 21ur-5116 No description available WB:WBGene00045829 21ur-2034 No description available WB:WBGene00045830 21ur-4950 No description available WB:WBGene00045831 21ur-646 No description available WB:WBGene00045832 21ur-1037 No description available WB:WBGene00045833 21ur-4327 No description available WB:WBGene00045834 21ur-552 Enriched in neurons based on RNA-seq studies. WB:WBGene00045835 21ur-1249 No description available WB:WBGene00045836 21ur-678 No description available WB:WBGene00045837 21ur-155 No description available WB:WBGene00045838 21ur-2719 No description available WB:WBGene00045839 21ur-4954 No description available WB:WBGene00045840 21ur-2725 No description available WB:WBGene00045841 21ur-436 No description available WB:WBGene00045842 21ur-1438 No description available WB:WBGene00045843 21ur-4160 No description available WB:WBGene00045844 21ur-1456 No description available WB:WBGene00045845 21ur-1701 No description available WB:WBGene00045846 21ur-4985 No description available WB:WBGene00045847 21ur-4756 No description available WB:WBGene00045848 21ur-2018 No description available WB:WBGene00045849 21ur-5274 No description available WB:WBGene00045850 21ur-2286 No description available WB:WBGene00045851 21ur-3316 No description available WB:WBGene00045852 21ur-4338 No description available WB:WBGene00045853 21ur-1220 No description available WB:WBGene00045854 21ur-2975 No description available WB:WBGene00045855 21ur-4682 No description available WB:WBGene00045856 21ur-3638 No description available WB:WBGene00045857 21ur-2386 No description available WB:WBGene00045858 21ur-5146 No description available WB:WBGene00045859 21ur-5253 No description available WB:WBGene00045860 21ur-31 No description available WB:WBGene00045861 21ur-1147 No description available WB:WBGene00045862 21ur-5013 No description available WB:WBGene00045863 21ur-1894 No description available WB:WBGene00045864 21ur-5172 No description available WB:WBGene00045865 21ur-768 No description available WB:WBGene00045866 21ur-3690 No description available WB:WBGene00045867 21ur-880 No description available WB:WBGene00045868 21ur-2141 No description available WB:WBGene00045869 21ur-178 No description available WB:WBGene00045870 21ur-2728 No description available WB:WBGene00045871 21ur-4340 No description available WB:WBGene00045872 21ur-906 No description available WB:WBGene00045873 21ur-2345 Enriched in neurons based on RNA-seq studies. WB:WBGene00045874 21ur-754 No description available WB:WBGene00045875 21ur-58 No description available WB:WBGene00045876 21ur-4409 Enriched in sensory neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00045877 21ur-2707 Enriched in neurons based on RNA-seq studies. WB:WBGene00045878 21ur-4669 No description available WB:WBGene00045879 21ur-4724 No description available WB:WBGene00045880 21ur-3842 No description available WB:WBGene00045881 21ur-3422 No description available WB:WBGene00045882 21ur-4299 Enriched in neurons based on RNA-seq studies. WB:WBGene00045883 21ur-752 No description available WB:WBGene00045884 21ur-250 No description available WB:WBGene00045885 21ur-1674 No description available WB:WBGene00045886 21ur-48 No description available WB:WBGene00045887 21ur-5194 No description available WB:WBGene00045888 21ur-3779 No description available WB:WBGene00045889 21ur-4711 No description available WB:WBGene00045890 21ur-5113 No description available WB:WBGene00045891 21ur-4772 No description available WB:WBGene00045892 21ur-1005 No description available WB:WBGene00045893 21ur-1904 No description available WB:WBGene00045894 21ur-3545 No description available WB:WBGene00045895 21ur-3246 No description available WB:WBGene00045896 21ur-2957 No description available WB:WBGene00045897 21ur-3781 No description available WB:WBGene00045898 21ur-1647 No description available WB:WBGene00045899 21ur-3253 No description available WB:WBGene00045900 21ur-3297 No description available WB:WBGene00045901 21ur-3291 No description available WB:WBGene00045902 21ur-793 No description available WB:WBGene00045903 21ur-1351 No description available WB:WBGene00045904 21ur-4662 No description available WB:WBGene00045905 21ur-5412 No description available WB:WBGene00045906 21ur-3674 No description available WB:WBGene00045907 21ur-3257 No description available WB:WBGene00045908 21ur-2819 No description available WB:WBGene00045909 21ur-1395 No description available WB:WBGene00045910 21ur-3768 No description available WB:WBGene00045911 21ur-3032 No description available WB:WBGene00045912 21ur-3577 No description available WB:WBGene00045913 21ur-1092 No description available WB:WBGene00045914 21ur-3731 Is affected by efa-6 and set-2 based on RNA-seq studies. WB:WBGene00045915 21ur-4477 No description available WB:WBGene00045916 21ur-3434 No description available WB:WBGene00045917 21ur-1067 No description available WB:WBGene00045918 21ur-4420 No description available WB:WBGene00045919 21ur-1495 No description available WB:WBGene00045920 21ur-3670 No description available WB:WBGene00045921 21ur-5228 No description available WB:WBGene00045922 21ur-4214 No description available WB:WBGene00045923 21ur-3896 No description available WB:WBGene00045924 21ur-1345 No description available WB:WBGene00045925 21ur-1172 No description available WB:WBGene00045926 21ur-274 No description available WB:WBGene00045927 21ur-2239 No description available WB:WBGene00045928 21ur-5209 No description available WB:WBGene00045929 21ur-257 No description available WB:WBGene00045930 21ur-844 No description available WB:WBGene00045931 21ur-4427 No description available WB:WBGene00045932 21ur-1418 No description available WB:WBGene00045933 21ur-1134 No description available WB:WBGene00045934 21ur-500 No description available WB:WBGene00045935 21ur-398 No description available WB:WBGene00045936 21ur-5171 No description available WB:WBGene00045937 21ur-1628 No description available WB:WBGene00045938 21ur-4316 No description available WB:WBGene00045939 21ur-488 No description available WB:WBGene00045940 21ur-529 No description available WB:WBGene00045941 21ur-4541 No description available WB:WBGene00045942 21ur-188 No description available WB:WBGene00045943 21ur-1799 No description available WB:WBGene00045944 21ur-2825 No description available WB:WBGene00045945 21ur-2812 No description available WB:WBGene00045946 21ur-894 No description available WB:WBGene00045947 21ur-3590 No description available WB:WBGene00045948 21ur-4033 No description available WB:WBGene00045949 21ur-1113 No description available WB:WBGene00045950 21ur-3425 No description available WB:WBGene00045951 21ur-2421 No description available WB:WBGene00045952 21ur-2941 No description available WB:WBGene00045953 21ur-2023 No description available WB:WBGene00045954 21ur-2048 No description available WB:WBGene00045955 21ur-5198 No description available WB:WBGene00045956 21ur-5048 No description available WB:WBGene00045957 21ur-938 No description available WB:WBGene00045958 21ur-4106 No description available WB:WBGene00045959 21ur-4442 No description available WB:WBGene00045960 21ur-4804 Enriched in neurons based on RNA-seq studies. WB:WBGene00045961 21ur-164 No description available WB:WBGene00045962 21ur-4126 No description available WB:WBGene00045963 21ur-3197 No description available WB:WBGene00045964 21ur-2594 No description available WB:WBGene00045965 21ur-4125 No description available WB:WBGene00045966 21ur-1954 No description available WB:WBGene00045967 21ur-4061 No description available WB:WBGene00045968 21ur-1524 No description available WB:WBGene00045969 21ur-1125 No description available WB:WBGene00045970 21ur-1664 No description available WB:WBGene00045971 21ur-3384 No description available WB:WBGene00045972 21ur-514 No description available WB:WBGene00045973 21ur-2657 No description available WB:WBGene00045974 21ur-804 Enriched in neurons based on RNA-seq studies. WB:WBGene00045975 21ur-2206 No description available WB:WBGene00045976 21ur-4551 No description available WB:WBGene00045977 21ur-2859 No description available WB:WBGene00045978 21ur-463 No description available WB:WBGene00045979 21ur-544 No description available WB:WBGene00045980 21ur-2129 No description available WB:WBGene00045981 21ur-992 No description available WB:WBGene00045982 21ur-1199 No description available WB:WBGene00045983 21ur-3771 No description available WB:WBGene00045984 21ur-4067 No description available WB:WBGene00045985 21ur-1790 No description available WB:WBGene00045986 21ur-1165 No description available WB:WBGene00045987 21ur-1441 No description available WB:WBGene00045988 21ur-649 No description available WB:WBGene00045989 21ur-584 No description available WB:WBGene00045990 21ur-3373 No description available WB:WBGene00045991 21ur-533 No description available WB:WBGene00045992 21ur-2309 No description available WB:WBGene00045993 21ur-1433 No description available WB:WBGene00045994 21ur-5323 No description available WB:WBGene00045995 21ur-13 No description available WB:WBGene00045996 21ur-2495 No description available WB:WBGene00045997 21ur-3903 No description available WB:WBGene00045998 21ur-700 No description available WB:WBGene00045999 21ur-4243 No description available WB:WBGene00046000 21ur-4161 No description available WB:WBGene00046001 21ur-2801 No description available WB:WBGene00046002 21ur-3048 No description available WB:WBGene00046003 21ur-2997 No description available WB:WBGene00046004 21ur-1621 No description available WB:WBGene00046005 21ur-3478 Enriched in neurons based on RNA-seq studies. WB:WBGene00046006 21ur-2362 No description available WB:WBGene00046007 21ur-4055 No description available WB:WBGene00046008 21ur-3360 No description available WB:WBGene00046009 21ur-2849 No description available WB:WBGene00046010 21ur-2648 No description available WB:WBGene00046011 21ur-5342 No description available WB:WBGene00046012 21ur-2424 No description available WB:WBGene00046013 21ur-5021 No description available WB:WBGene00046014 21ur-2448 No description available WB:WBGene00046015 21ur-963 No description available WB:WBGene00046016 21ur-2994 No description available WB:WBGene00046017 21ur-50 No description available WB:WBGene00046018 21ur-4221 No description available WB:WBGene00046019 21ur-1857 No description available WB:WBGene00046020 21ur-3185 No description available WB:WBGene00046021 21ur-76 Enriched in neurons based on RNA-seq studies. WB:WBGene00046022 21ur-2945 No description available WB:WBGene00046023 21ur-292 No description available WB:WBGene00046024 21ur-2625 No description available WB:WBGene00046025 21ur-5231 No description available WB:WBGene00046026 21ur-2556 No description available WB:WBGene00046027 21ur-2007 No description available WB:WBGene00046028 21ur-1881 No description available WB:WBGene00046029 21ur-505 Enriched in neurons based on RNA-seq studies. WB:WBGene00046030 21ur-3209 Enriched in neurons based on RNA-seq studies. WB:WBGene00046031 21ur-1747 No description available WB:WBGene00046032 21ur-4085 No description available WB:WBGene00046033 21ur-4741 No description available WB:WBGene00046034 21ur-4381 No description available WB:WBGene00046035 21ur-3101 No description available WB:WBGene00046036 21ur-4419 No description available WB:WBGene00046037 21ur-1690 No description available WB:WBGene00046038 21ur-729 No description available WB:WBGene00046039 21ur-1340 No description available WB:WBGene00046040 21ur-1659 No description available WB:WBGene00046041 21ur-2213 No description available WB:WBGene00046042 21ur-2163 No description available WB:WBGene00046043 21ur-2794 No description available WB:WBGene00046044 21ur-3565 No description available WB:WBGene00046045 21ur-3761 No description available WB:WBGene00046046 21ur-1920 No description available WB:WBGene00046047 21ur-2923 No description available WB:WBGene00046048 21ur-869 No description available WB:WBGene00046049 21ur-5303 No description available WB:WBGene00046050 21ur-1865 No description available WB:WBGene00046051 21ur-631 No description available WB:WBGene00046052 21ur-825 No description available WB:WBGene00046053 21ur-3599 Is affected by daf-2 based on microarray studies. WB:WBGene00046054 21ur-5208 No description available WB:WBGene00046055 21ur-1934 No description available WB:WBGene00046056 21ur-3544 No description available WB:WBGene00046057 21ur-1696 No description available WB:WBGene00046058 21ur-1274 Enriched in neurons based on RNA-seq studies. WB:WBGene00046059 21ur-1837 No description available WB:WBGene00046060 21ur-2661 Enriched in neurons based on RNA-seq studies. WB:WBGene00046061 21ur-919 No description available WB:WBGene00046062 21ur-3336 No description available WB:WBGene00046063 21ur-3570 No description available WB:WBGene00046064 21ur-5051 No description available WB:WBGene00046065 21ur-1383 No description available WB:WBGene00046066 21ur-391 Enriched in neurons based on RNA-seq studies. WB:WBGene00046067 21ur-4480 No description available WB:WBGene00046068 21ur-1845 No description available WB:WBGene00046069 21ur-3010 No description available WB:WBGene00046070 21ur-3871 No description available WB:WBGene00046071 21ur-2883 No description available WB:WBGene00046072 21ur-727 No description available WB:WBGene00046073 21ur-1591 No description available WB:WBGene00046074 21ur-1918 No description available WB:WBGene00046075 21ur-4616 No description available WB:WBGene00046076 21ur-5404 No description available WB:WBGene00046077 21ur-5213 Enriched in neurons based on RNA-seq studies. WB:WBGene00046078 21ur-299 No description available WB:WBGene00046079 21ur-1001 No description available WB:WBGene00046080 21ur-1426 No description available WB:WBGene00046081 21ur-4624 No description available WB:WBGene00046082 21ur-912 No description available WB:WBGene00046083 21ur-2734 No description available WB:WBGene00046084 21ur-1042 No description available WB:WBGene00046085 21ur-23 No description available WB:WBGene00046086 21ur-325 No description available WB:WBGene00046087 21ur-734 No description available WB:WBGene00046088 21ur-409 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 and lpd-3 based on RNA-seq studies. WB:WBGene00046089 21ur-2171 No description available WB:WBGene00046090 21ur-5053 No description available WB:WBGene00046091 21ur-1566 No description available WB:WBGene00046092 21ur-41 No description available WB:WBGene00046093 21ur-2297 No description available WB:WBGene00046094 21ur-265 No description available WB:WBGene00046095 21ur-2391 No description available WB:WBGene00046096 21ur-1686 No description available WB:WBGene00046097 21ur-971 No description available WB:WBGene00046098 21ur-4091 No description available WB:WBGene00046099 21ur-2017 No description available WB:WBGene00046100 21ur-2779 No description available WB:WBGene00046101 21ur-146 No description available WB:WBGene00046102 21ur-4653 No description available WB:WBGene00046103 21ur-3464 No description available WB:WBGene00046104 21ur-4454 No description available WB:WBGene00046105 21ur-191 No description available WB:WBGene00046106 21ur-480 No description available WB:WBGene00046107 21ur-400 No description available WB:WBGene00046108 21ur-4846 No description available WB:WBGene00046109 21ur-2935 No description available WB:WBGene00046110 21ur-1289 No description available WB:WBGene00046111 21ur-4116 No description available WB:WBGene00046112 21ur-2751 No description available WB:WBGene00046113 21ur-1190 No description available WB:WBGene00046114 21ur-2298 No description available WB:WBGene00046115 21ur-2939 No description available WB:WBGene00046116 21ur-2746 No description available WB:WBGene00046117 21ur-2479 Is affected by lem-2 based on RNA-seq studies. WB:WBGene00046118 21ur-3327 No description available WB:WBGene00046119 21ur-2409 No description available WB:WBGene00046120 21ur-3797 No description available WB:WBGene00046121 21ur-3554 No description available WB:WBGene00046122 21ur-4738 No description available WB:WBGene00046123 21ur-4521 No description available WB:WBGene00046124 21ur-2672 No description available WB:WBGene00046125 21ur-1236 No description available WB:WBGene00046126 21ur-2837 No description available WB:WBGene00046127 21ur-3884 No description available WB:WBGene00046128 21ur-305 No description available WB:WBGene00046129 21ur-4457 No description available WB:WBGene00046130 21ur-3376 No description available WB:WBGene00046131 21ur-2193 Enriched in neurons based on RNA-seq studies. WB:WBGene00046132 21ur-4375 No description available WB:WBGene00046133 21ur-2638 No description available WB:WBGene00046134 21ur-3999 No description available WB:WBGene00046135 21ur-1264 No description available WB:WBGene00046136 21ur-888 No description available WB:WBGene00046137 21ur-1033 No description available WB:WBGene00046138 21ur-2220 No description available WB:WBGene00046139 21ur-86 Enriched in neurons based on RNA-seq studies. WB:WBGene00046140 21ur-3206 No description available WB:WBGene00046141 21ur-487 No description available WB:WBGene00046142 21ur-983 No description available WB:WBGene00046143 21ur-4973 No description available WB:WBGene00046144 21ur-3756 No description available WB:WBGene00046145 21ur-3658 No description available WB:WBGene00046146 21ur-3158 No description available WB:WBGene00046147 21ur-3223 No description available WB:WBGene00046148 21ur-2402 No description available WB:WBGene00046149 21ur-225 No description available WB:WBGene00046150 21ur-4885 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00046151 21ur-2319 No description available WB:WBGene00046152 21ur-4143 No description available WB:WBGene00046153 21ur-4749 No description available WB:WBGene00046154 21ur-4599 No description available WB:WBGene00046155 21ur-5377 No description available WB:WBGene00046156 21ur-1546 No description available WB:WBGene00046157 21ur-2076 No description available WB:WBGene00046158 21ur-1153 No description available WB:WBGene00046159 21ur-5181 No description available WB:WBGene00046160 21ur-1718 No description available WB:WBGene00046161 21ur-816 No description available WB:WBGene00046162 21ur-1402 No description available WB:WBGene00046163 21ur-361 No description available WB:WBGene00046164 21ur-5001 No description available WB:WBGene00046165 21ur-410 No description available WB:WBGene00046166 21ur-2455 No description available WB:WBGene00046167 21ur-2338 No description available WB:WBGene00046168 21ur-2603 No description available WB:WBGene00046169 21ur-4763 No description available WB:WBGene00046170 21ur-1512 No description available WB:WBGene00046171 21ur-51 No description available WB:WBGene00046172 21ur-1279 No description available WB:WBGene00046173 21ur-3233 No description available WB:WBGene00046174 21ur-653 No description available WB:WBGene00046175 21ur-745 No description available WB:WBGene00046176 21ur-3971 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00046177 21ur-2344 No description available WB:WBGene00046178 21ur-1872 No description available WB:WBGene00046179 21ur-663 No description available WB:WBGene00046180 21ur-498 No description available WB:WBGene00046181 21ur-1650 No description available WB:WBGene00046182 21ur-3294 Enriched in neurons based on RNA-seq studies. WB:WBGene00046183 21ur-4540 Enriched in neurons based on RNA-seq studies. WB:WBGene00046184 21ur-491 No description available WB:WBGene00046185 21ur-546 No description available WB:WBGene00046186 21ur-1420 No description available WB:WBGene00046187 21ur-4 No description available WB:WBGene00046188 21ur-2647 No description available WB:WBGene00046189 21ur-2354 Enriched in neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00046190 21ur-3976 No description available WB:WBGene00046191 21ur-3788 No description available WB:WBGene00046192 21ur-3682 No description available WB:WBGene00046193 21ur-3287 Is affected by Ketamine based on RNA-seq studies. WB:WBGene00046194 21ur-2435 No description available WB:WBGene00046195 21ur-3526 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00046196 21ur-1266 No description available WB:WBGene00046197 21ur-1841 No description available WB:WBGene00046198 21ur-1812 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00046199 21ur-3654 No description available WB:WBGene00046200 21ur-2225 No description available WB:WBGene00046201 21ur-5313 No description available WB:WBGene00046202 21ur-4236 No description available WB:WBGene00046203 21ur-1177 No description available WB:WBGene00046204 21ur-1120 No description available WB:WBGene00046205 21ur-5165 No description available WB:WBGene00046206 21ur-2890 No description available WB:WBGene00046207 21ur-3238 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00046208 21ur-1304 No description available WB:WBGene00046209 21ur-333 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00046210 21ur-5266 No description available WB:WBGene00046211 21ur-3035 No description available WB:WBGene00046212 21ur-2987 No description available WB:WBGene00046213 21ur-4622 No description available WB:WBGene00046214 21ur-3184 No description available WB:WBGene00046215 21ur-377 No description available WB:WBGene00046216 21ur-3528 No description available WB:WBGene00046217 21ur-3408 No description available WB:WBGene00046218 21ur-2688 No description available WB:WBGene00046219 21ur-38 No description available WB:WBGene00046220 21ur-3131 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00046221 21ur-3061 No description available WB:WBGene00046222 21ur-5453 No description available WB:WBGene00046223 21ur-5217 No description available WB:WBGene00046224 21ur-4164 No description available WB:WBGene00046225 21ur-2035 No description available WB:WBGene00046226 21ur-3271 No description available WB:WBGene00046227 21ur-1936 No description available WB:WBGene00046228 21ur-692 No description available WB:WBGene00046229 21ur-4699 No description available WB:WBGene00046230 21ur-1835 No description available WB:WBGene00046231 21ur-102 No description available WB:WBGene00046232 21ur-1053 No description available WB:WBGene00046233 21ur-4845 No description available WB:WBGene00046234 21ur-2303 No description available WB:WBGene00046235 21ur-3441 No description available WB:WBGene00046236 21ur-4426 No description available WB:WBGene00046237 21ur-1968 No description available WB:WBGene00046238 21ur-5086 No description available WB:WBGene00046239 21ur-881 No description available WB:WBGene00046240 21ur-4792 No description available WB:WBGene00046241 21ur-3516 No description available WB:WBGene00046242 21ur-4291 Is affected by set-2 based on RNA-seq studies. WB:WBGene00046243 21ur-4581 No description available WB:WBGene00046244 21ur-4326 No description available WB:WBGene00046245 21ur-4965 No description available WB:WBGene00046246 21ur-4605 No description available WB:WBGene00046247 21ur-572 No description available WB:WBGene00046248 21ur-197 No description available WB:WBGene00046249 21ur-1283 No description available WB:WBGene00046250 21ur-2119 Enriched in neurons based on RNA-seq studies. WB:WBGene00046251 21ur-579 No description available WB:WBGene00046252 21ur-390 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00046253 21ur-5384 No description available WB:WBGene00046254 21ur-1273 No description available WB:WBGene00046255 21ur-1038 No description available WB:WBGene00046256 21ur-3196 No description available WB:WBGene00046257 21ur-4577 Enriched in neurons based on RNA-seq studies. WB:WBGene00046258 21ur-654 No description available WB:WBGene00046259 21ur-4511 No description available WB:WBGene00046260 21ur-2695 No description available WB:WBGene00046261 21ur-4114 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00046262 21ur-21 No description available WB:WBGene00046263 21ur-3635 No description available WB:WBGene00046264 21ur-1258 No description available WB:WBGene00046265 21ur-2903 No description available WB:WBGene00046266 21ur-4849 No description available WB:WBGene00046267 21ur-297 Enriched in neurons based on RNA-seq studies. WB:WBGene00046268 21ur-416 No description available WB:WBGene00046269 21ur-4638 No description available WB:WBGene00046270 21ur-2058 No description available WB:WBGene00046271 21ur-1762 No description available WB:WBGene00046272 21ur-4915 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00046273 21ur-4134 No description available WB:WBGene00046274 21ur-597 No description available WB:WBGene00046275 21ur-1241 Is affected by emr-1; lem-2; and rnp-6 based on RNA-seq studies. WB:WBGene00046276 21ur-3809 No description available WB:WBGene00046277 21ur-2131 No description available WB:WBGene00046278 21ur-610 No description available WB:WBGene00046279 21ur-2442 No description available WB:WBGene00046280 21ur-3189 No description available WB:WBGene00046281 21ur-606 Enriched in neurons based on RNA-seq studies. WB:WBGene00046282 21ur-1640 No description available WB:WBGene00046283 21ur-499 No description available WB:WBGene00046284 21ur-5242 No description available WB:WBGene00046285 21ur-311 No description available WB:WBGene00046286 21ur-5233 No description available WB:WBGene00046287 21ur-4694 No description available WB:WBGene00046288 21ur-2915 No description available WB:WBGene00046289 21ur-5066 No description available WB:WBGene00046290 21ur-5038 No description available WB:WBGene00046291 21ur-337 No description available WB:WBGene00046292 21ur-1079 No description available WB:WBGene00046293 21ur-1702 No description available WB:WBGene00046294 21ur-2380 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00046295 21ur-1206 No description available WB:WBGene00046296 21ur-2530 No description available WB:WBGene00046297 21ur-1234 No description available WB:WBGene00046298 21ur-2468 No description available WB:WBGene00046299 21ur-1867 Enriched in neurons based on RNA-seq studies. WB:WBGene00046300 21ur-554 No description available WB:WBGene00046301 21ur-4813 No description available WB:WBGene00046302 21ur-2374 No description available WB:WBGene00046303 21ur-4759 No description available WB:WBGene00046304 21ur-5112 No description available WB:WBGene00046305 21ur-3997 No description available WB:WBGene00046306 21ur-1913 No description available WB:WBGene00046307 21ur-648 No description available WB:WBGene00046308 21ur-362 No description available WB:WBGene00046309 21ur-2727 No description available WB:WBGene00046310 21ur-4644 No description available WB:WBGene00046311 21ur-245 No description available WB:WBGene00046312 21ur-2870 No description available WB:WBGene00046313 21ur-3912 No description available WB:WBGene00046314 21ur-5435 No description available WB:WBGene00046315 21ur-4869 Enriched in neurons based on RNA-seq studies. WB:WBGene00046316 21ur-5262 No description available WB:WBGene00046317 21ur-3509 No description available WB:WBGene00046318 21ur-4870 No description available WB:WBGene00046319 21ur-193 No description available WB:WBGene00046320 21ur-2840 No description available WB:WBGene00046321 21ur-3611 No description available WB:WBGene00046322 21ur-3919 No description available WB:WBGene00046323 21ur-3143 No description available WB:WBGene00046324 21ur-2168 No description available WB:WBGene00046325 21ur-2449 No description available WB:WBGene00046326 21ur-585 No description available WB:WBGene00046327 21ur-67 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00046328 21ur-456 No description available WB:WBGene00046329 21ur-2278 No description available WB:WBGene00046330 21ur-4031 Enriched in neurons based on RNA-seq studies. WB:WBGene00046331 21ur-4971 No description available WB:WBGene00046332 21ur-3261 No description available WB:WBGene00046333 21ur-4319 No description available WB:WBGene00046334 21ur-4629 No description available WB:WBGene00046335 21ur-2814 No description available WB:WBGene00046336 21ur-1248 No description available WB:WBGene00046337 21ur-2162 No description available WB:WBGene00046338 21ur-5002 No description available WB:WBGene00046339 21ur-3454 No description available WB:WBGene00046340 21ur-5029 No description available WB:WBGene00046341 21ur-1154 No description available WB:WBGene00046342 21ur-2871 No description available WB:WBGene00046343 21ur-2955 No description available WB:WBGene00046344 21ur-4309 No description available WB:WBGene00046345 21ur-3647 Enriched in neurons based on RNA-seq studies. WB:WBGene00046346 21ur-4399 No description available WB:WBGene00046347 21ur-1187 No description available WB:WBGene00046348 21ur-342 No description available WB:WBGene00046349 21ur-1886 No description available WB:WBGene00046350 21ur-3314 No description available WB:WBGene00046351 21ur-3150 No description available WB:WBGene00046352 21ur-3433 No description available WB:WBGene00046353 21ur-2960 No description available WB:WBGene00046354 21ur-4268 No description available WB:WBGene00046355 21ur-4549 No description available WB:WBGene00046356 21ur-4831 Enriched in neurons based on RNA-seq studies. WB:WBGene00046357 21ur-2820 No description available WB:WBGene00046358 21ur-4185 No description available WB:WBGene00046359 21ur-1750 No description available WB:WBGene00046360 21ur-4712 No description available WB:WBGene00046361 21ur-5450 No description available WB:WBGene00046362 21ur-3114 No description available WB:WBGene00046363 21ur-4436 No description available WB:WBGene00046364 21ur-4924 No description available WB:WBGene00046365 21ur-532 No description available WB:WBGene00046366 21ur-673 No description available WB:WBGene00046367 21ur-3062 No description available WB:WBGene00046368 21ur-920 No description available WB:WBGene00046369 21ur-4717 No description available WB:WBGene00046370 21ur-3175 No description available WB:WBGene00046371 21ur-1570 No description available WB:WBGene00046372 21ur-4897 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00046373 21ur-4857 No description available WB:WBGene00046374 21ur-4539 Enriched in neurons based on RNA-seq studies. WB:WBGene00046375 21ur-3397 No description available WB:WBGene00046376 21ur-81 No description available WB:WBGene00046377 21ur-3921 No description available WB:WBGene00046378 21ur-1103 No description available WB:WBGene00046379 21ur-147 No description available WB:WBGene00046380 21ur-3107 No description available WB:WBGene00046381 21ur-4508 No description available WB:WBGene00046382 21ur-5258 No description available WB:WBGene00046383 21ur-3174 No description available WB:WBGene00046384 21ur-4931 No description available WB:WBGene00046385 21ur-5441 No description available WB:WBGene00046386 21ur-1119 No description available WB:WBGene00046387 21ur-350 No description available WB:WBGene00046388 21ur-5106 No description available WB:WBGene00046389 21ur-492 No description available WB:WBGene00046390 21ur-1602 No description available WB:WBGene00046391 21ur-2720 No description available WB:WBGene00046392 21ur-2453 No description available WB:WBGene00046393 21ur-5287 No description available WB:WBGene00046394 21ur-1503 No description available WB:WBGene00046395 21ur-4681 No description available WB:WBGene00046396 21ur-5414 No description available WB:WBGene00046397 21ur-1460 No description available WB:WBGene00046398 21ur-2584 No description available WB:WBGene00046399 21ur-2750 No description available WB:WBGene00046400 21ur-769 No description available WB:WBGene00046401 21ur-2251 No description available WB:WBGene00046402 21ur-954 No description available WB:WBGene00046403 21ur-3642 No description available WB:WBGene00046404 21ur-4955 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00046405 21ur-1198 Enriched in neurons based on RNA-seq studies. WB:WBGene00046406 21ur-5338 No description available WB:WBGene00046407 21ur-1897 No description available WB:WBGene00046408 21ur-1525 No description available WB:WBGene00046409 21ur-241 No description available WB:WBGene00046410 21ur-645 No description available WB:WBGene00046411 21ur-4453 No description available WB:WBGene00046412 21ur-3834 No description available WB:WBGene00046413 21ur-4212 No description available WB:WBGene00046414 21ur-4330 No description available WB:WBGene00046415 21ur-1906 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00046416 21ur-3796 No description available WB:WBGene00046417 21ur-1212 No description available WB:WBGene00046418 21ur-1310 No description available WB:WBGene00046419 21ur-1228 No description available WB:WBGene00046420 21ur-403 No description available WB:WBGene00046421 21ur-281 Enriched in neurons based on RNA-seq studies. WB:WBGene00046422 21ur-5358 No description available WB:WBGene00046423 21ur-4341 No description available WB:WBGene00046424 21ur-1084 No description available WB:WBGene00046425 21ur-3843 No description available WB:WBGene00046426 21ur-3120 No description available WB:WBGene00046427 21ur-5254 No description available WB:WBGene00046428 21ur-2285 No description available WB:WBGene00046429 21ur-5109 No description available WB:WBGene00046430 21ur-4986 No description available WB:WBGene00046431 21ur-3927 No description available WB:WBGene00046432 21ur-2097 No description available WB:WBGene00046433 21ur-3008 No description available WB:WBGene00046434 21ur-755 No description available WB:WBGene00046435 21ur-1626 No description available WB:WBGene00046436 21ur-4588 No description available WB:WBGene00046437 21ur-1146 No description available WB:WBGene00046438 21ur-2159 No description available WB:WBGene00046439 21ur-2711 No description available WB:WBGene00046440 21ur-1703 No description available WB:WBGene00046441 21ur-2888 No description available WB:WBGene00046442 21ur-4458 No description available WB:WBGene00046443 21ur-2030 No description available WB:WBGene00046444 21ur-2920 No description available WB:WBGene00046445 21ur-2974 No description available WB:WBGene00046446 21ur-4004 No description available WB:WBGene00046447 21ur-701 No description available WB:WBGene00046448 21ur-1423 No description available WB:WBGene00046449 21ur-4410 No description available WB:WBGene00046450 21ur-2410 No description available WB:WBGene00046451 21ur-3016 No description available WB:WBGene00046452 21ur-5355 No description available WB:WBGene00046453 21ur-5040 No description available WB:WBGene00046454 21ur-1439 No description available WB:WBGene00046455 21ur-156 No description available WB:WBGene00046456 21ur-234 No description available WB:WBGene00046457 21ur-4951 No description available WB:WBGene00046458 21ur-753 Enriched in neurons based on RNA-seq studies. WB:WBGene00046459 21ur-5280 No description available WB:WBGene00046460 21ur-2847 No description available WB:WBGene00046461 21ur-2142 No description available WB:WBGene00046462 21ur-4554 No description available WB:WBGene00046463 21ur-83 No description available WB:WBGene00046464 21ur-1768 No description available WB:WBGene00046465 21ur-871 No description available WB:WBGene00046466 21ur-158 No description available WB:WBGene00046467 21ur-1494 No description available WB:WBGene00046468 21ur-2203 No description available WB:WBGene00046469 21ur-1141 Enriched in neurons based on RNA-seq studies. WB:WBGene00046470 21ur-4814 No description available WB:WBGene00046471 21ur-115 No description available WB:WBGene00046472 21ur-4852 No description available WB:WBGene00046473 21ur-2731 No description available WB:WBGene00046474 21ur-2169 No description available WB:WBGene00046475 21ur-4430 Enriched in neurons based on RNA-seq studies. WB:WBGene00046476 21ur-1163 No description available WB:WBGene00046477 21ur-2396 No description available WB:WBGene00046478 21ur-905 No description available WB:WBGene00046479 21ur-5125 No description available WB:WBGene00046480 21ur-5361 No description available WB:WBGene00046481 21ur-3075 No description available WB:WBGene00046482 21ur-97 No description available WB:WBGene00046483 21ur-4349 No description available WB:WBGene00046484 21ur-3812 No description available WB:WBGene00046485 21ur-1976 Is affected by eat-2 based on microarray studies. WB:WBGene00046486 21ur-561 No description available WB:WBGene00046487 21ur-4518 No description available WB:WBGene00046488 21ur-351 Enriched in neurons based on RNA-seq studies. WB:WBGene00046489 21ur-2187 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00046490 21ur-4475 No description available WB:WBGene00046491 21ur-1317 No description available WB:WBGene00046492 21ur-876 No description available WB:WBGene00046493 21ur-1996 No description available WB:WBGene00046494 21ur-4824 No description available WB:WBGene00046495 21ur-765 No description available WB:WBGene00046496 21ur-4253 No description available WB:WBGene00046497 21ur-3346 No description available WB:WBGene00046498 21ur-3866 No description available WB:WBGene00046499 21ur-3052 Enriched in neurons based on RNA-seq studies. WB:WBGene00046500 21ur-396 No description available WB:WBGene00046501 21ur-4401 No description available WB:WBGene00046502 21ur-4310 No description available WB:WBGene00046503 21ur-25 No description available WB:WBGene00046504 21ur-2355 No description available WB:WBGene00046505 21ur-1775 No description available WB:WBGene00046506 21ur-1726 No description available WB:WBGene00046507 21ur-204 No description available WB:WBGene00046508 21ur-2708 No description available WB:WBGene00046509 21ur-718 No description available WB:WBGene00046510 21ur-5088 No description available WB:WBGene00046511 21ur-5074 No description available WB:WBGene00046512 21ur-4359 No description available WB:WBGene00046513 21ur-9 No description available WB:WBGene00046514 21ur-2087 No description available WB:WBGene00046515 21ur-3136 No description available WB:WBGene00046516 21ur-212 No description available WB:WBGene00046517 21ur-5064 No description available WB:WBGene00046518 21ur-1461 Is affected by daf-2 based on microarray studies. WB:WBGene00046519 21ur-3531 No description available WB:WBGene00046520 21ur-4566 No description available WB:WBGene00046521 21ur-3755 No description available WB:WBGene00046522 21ur-5324 Enriched in neurons based on RNA-seq studies. WB:WBGene00046523 21ur-4766 No description available WB:WBGene00046524 21ur-823 No description available WB:WBGene00046525 21ur-3001 No description available WB:WBGene00046526 21ur-1326 No description available WB:WBGene00046527 21ur-4795 No description available WB:WBGene00046528 21ur-1581 Enriched in neurons based on RNA-seq studies. WB:WBGene00046529 21ur-1465 No description available WB:WBGene00046530 21ur-5175 Is affected by xpf-1 based on RNA-seq studies. WB:WBGene00046531 21ur-699 Enriched in neurons based on RNA-seq studies. WB:WBGene00046532 21ur-1585 No description available WB:WBGene00046533 21ur-3089 No description available WB:WBGene00046534 21ur-807 Is affected by meg-3 and meg-4 based on RNA-seq studies. WB:WBGene00046535 21ur-1127 No description available WB:WBGene00046536 21ur-2153 No description available WB:WBGene00046537 21ur-4574 No description available WB:WBGene00046538 21ur-1019 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00046539 21ur-3381 No description available WB:WBGene00046540 21ur-3819 No description available WB:WBGene00046541 21ur-2417 No description available WB:WBGene00046542 21ur-4463 Is affected by eat-2 based on microarray studies. WB:WBGene00046543 21ur-619 No description available WB:WBGene00046544 21ur-1489 Enriched in neurons based on RNA-seq studies. WB:WBGene00046545 21ur-10 No description available WB:WBGene00046546 21ur-583 No description available WB:WBGene00046547 21ur-1688 No description available WB:WBGene00046548 21ur-2743 No description available WB:WBGene00046549 21ur-2149 No description available WB:WBGene00046550 21ur-4356 No description available WB:WBGene00046551 21ur-2090 No description available WB:WBGene00046552 21ur-3850 No description available WB:WBGene00046553 21ur-1368 No description available WB:WBGene00046554 21ur-1693 No description available WB:WBGene00046555 21ur-14 Enriched in neurons based on RNA-seq studies. WB:WBGene00046556 21ur-3338 No description available WB:WBGene00046557 21ur-4736 No description available WB:WBGene00046558 21ur-1746 No description available WB:WBGene00046559 21ur-4068 No description available WB:WBGene00046560 21ur-2143 Is affected by eat-2 based on microarray studies. WB:WBGene00046561 21ur-3749 No description available WB:WBGene00046562 21ur-462 No description available WB:WBGene00046563 21ur-4142 No description available WB:WBGene00046564 21ur-1600 Is affected by nfki-1 and ikb-1 based on RNA-seq studies. WB:WBGene00046565 21ur-1195 No description available WB:WBGene00046566 21ur-3772 No description available WB:WBGene00046567 21ur-937 No description available WB:WBGene00046568 21ur-4380 No description available WB:WBGene00046569 21ur-4805 No description available WB:WBGene00046570 21ur-1715 No description available WB:WBGene00046571 21ur-4610 No description available WB:WBGene00046572 21ur-4027 No description available WB:WBGene00046573 21ur-4289 No description available WB:WBGene00046574 21ur-266 No description available WB:WBGene00046575 21ur-4086 No description available WB:WBGene00046576 21ur-680 No description available WB:WBGene00046577 21ur-4193 No description available WB:WBGene00046578 21ur-4464 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00046579 21ur-4014 No description available WB:WBGene00046580 21ur-4244 No description available WB:WBGene00046581 21ur-1201 No description available WB:WBGene00046582 21ur-973 No description available WB:WBGene00046583 21ur-2809 No description available WB:WBGene00046584 21ur-205 No description available WB:WBGene00046585 21ur-1545 No description available WB:WBGene00046586 21ur-4372 Enriched in neurons based on RNA-seq studies. WB:WBGene00046587 21ur-2040 No description available WB:WBGene00046588 21ur-3215 No description available WB:WBGene00046589 21ur-2999 No description available WB:WBGene00046590 21ur-1663 Enriched in neurons based on RNA-seq studies. WB:WBGene00046591 21ur-3157 No description available WB:WBGene00046592 21ur-2525 No description available WB:WBGene00046593 21ur-4443 No description available WB:WBGene00046594 21ur-3902 No description available WB:WBGene00046595 21ur-4109 No description available WB:WBGene00046596 21ur-1412 No description available WB:WBGene00046597 21ur-1508 No description available WB:WBGene00046598 21ur-2555 No description available WB:WBGene00046599 21ur-4015 No description available WB:WBGene00046600 21ur-4062 No description available WB:WBGene00046601 21ur-397 No description available WB:WBGene00046602 21ur-2860 No description available WB:WBGene00046603 21ur-2595 No description available WB:WBGene00046604 21ur-2996 No description available WB:WBGene00046605 21ur-4823 No description available WB:WBGene00046606 21ur-4329 No description available WB:WBGene00046607 21ur-2944 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00046608 21ur-2501 Is affected by spr-5 based on RNA-seq studies. WB:WBGene00046609 21ur-5299 No description available WB:WBGene00046610 21ur-2995 Enriched in neurons based on RNA-seq studies. WB:WBGene00046611 21ur-2081 No description available WB:WBGene00046612 21ur-3076 No description available WB:WBGene00046613 21ur-1430 No description available WB:WBGene00046614 21ur-4150 No description available WB:WBGene00046615 21ur-5343 No description available WB:WBGene00046616 21ur-2418 No description available WB:WBGene00046617 21ur-3723 No description available WB:WBGene00046618 21ur-3479 No description available WB:WBGene00046619 21ur-3712 No description available WB:WBGene00046620 21ur-1691 No description available WB:WBGene00046621 21ur-3543 No description available WB:WBGene00046622 21ur-726 No description available WB:WBGene00046623 21ur-3854 No description available WB:WBGene00046624 21ur-517 No description available WB:WBGene00046625 21ur-728 No description available WB:WBGene00046626 21ur-5397 No description available WB:WBGene00046627 21ur-2802 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00046628 21ur-2353 No description available WB:WBGene00046629 21ur-2084 No description available WB:WBGene00046630 21ur-1825 No description available WB:WBGene00046631 21ur-515 No description available WB:WBGene00046632 21ur-3963 No description available WB:WBGene00046633 21ur-2487 No description available WB:WBGene00046634 21ur-1785 No description available WB:WBGene00046635 21ur-5016 No description available WB:WBGene00046636 21ur-4153 Is affected by set-2 based on RNA-seq studies. WB:WBGene00046637 21ur-3258 No description available WB:WBGene00046638 21ur-833 No description available WB:WBGene00046639 21ur-3332 No description available WB:WBGene00046640 21ur-2811 No description available WB:WBGene00046641 21ur-4906 No description available WB:WBGene00046642 21ur-3382 No description available WB:WBGene00046643 21ur-4222 No description available WB:WBGene00046644 21ur-2216 No description available WB:WBGene00046645 21ur-3208 Is affected by hmg-3 and rnp-6 based on RNA-seq studies. WB:WBGene00046646 21ur-508 No description available WB:WBGene00046647 21ur-1836 No description available WB:WBGene00046648 21ur-3389 No description available WB:WBGene00046649 21ur-2 No description available WB:WBGene00046650 21ur-1925 No description available WB:WBGene00046651 21ur-2245 No description available WB:WBGene00046652 21ur-187 No description available WB:WBGene00046653 21ur-3546 No description available WB:WBGene00046654 21ur-3780 No description available WB:WBGene00046655 21ur-182 No description available WB:WBGene00046656 21ur-1556 No description available WB:WBGene00046657 21ur-3481 No description available WB:WBGene00046658 21ur-4771 No description available WB:WBGene00046659 21ur-1987 No description available WB:WBGene00046660 21ur-5424 No description available WB:WBGene00046661 21ur-4494 No description available WB:WBGene00046662 21ur-4261 No description available WB:WBGene00046663 21ur-885 No description available WB:WBGene00046664 21ur-1093 No description available WB:WBGene00046665 21ur-4620 No description available WB:WBGene00046666 21ur-4277 No description available WB:WBGene00046667 21ur-3778 No description available WB:WBGene00046668 21ur-4944 No description available WB:WBGene00046669 21ur-3673 Enriched in neurons based on RNA-seq studies. WB:WBGene00046670 21ur-5395 No description available WB:WBGene00046671 21ur-3566 No description available WB:WBGene00046672 21ur-1252 No description available WB:WBGene00046673 21ur-4099 No description available WB:WBGene00046674 21ur-3404 No description available WB:WBGene00046675 21ur-3769 No description available WB:WBGene00046676 21ur-4203 No description available WB:WBGene00046677 21ur-2228 No description available WB:WBGene00046678 21ur-4936 No description available WB:WBGene00046679 21ur-1316 No description available WB:WBGene00046680 21ur-57 No description available WB:WBGene00046681 21ur-4860 No description available WB:WBGene00046682 21ur-2109 No description available WB:WBGene00046683 21ur-3369 No description available WB:WBGene00046684 21ur-797 No description available WB:WBGene00046685 21ur-2403 No description available WB:WBGene00046686 21ur-1066 No description available WB:WBGene00046687 21ur-3049 No description available WB:WBGene00046688 21ur-5193 No description available WB:WBGene00046689 21ur-4331 No description available WB:WBGene00046690 21ur-256 No description available WB:WBGene00046691 21ur-4654 No description available WB:WBGene00046692 21ur-2123 No description available WB:WBGene00046693 21ur-3249 No description available WB:WBGene00046694 21ur-5138 No description available WB:WBGene00046695 21ur-2096 No description available WB:WBGene00046696 21ur-964 No description available WB:WBGene00046697 21ur-3410 Enriched in neurons based on RNA-seq studies. WB:WBGene00046698 21ur-328 Enriched in AFD based on RNA-seq studies. Is affected by sod-2; atfs-1; and camt-1 based on RNA-seq studies. WB:WBGene00046699 21ur-1396 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00046700 21ur-1798 No description available WB:WBGene00046701 21ur-1171 No description available WB:WBGene00046702 21ur-3424 No description available WB:WBGene00046703 21ur-897 No description available WB:WBGene00046704 21ur-666 No description available WB:WBGene00046705 21ur-5045 No description available WB:WBGene00046706 21ur-2940 No description available WB:WBGene00046707 21ur-1948 No description available WB:WBGene00046708 21ur-4092 No description available WB:WBGene00046709 21ur-2043 No description available WB:WBGene00046710 21ur-1209 No description available WB:WBGene00046711 21ur-3245 No description available WB:WBGene00046712 21ur-1004 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00046713 21ur-5197 No description available WB:WBGene00046714 21ur-3254 No description available WB:WBGene00046715 21ur-843 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00046716 21ur-2016 Enriched in neurons based on RNA-seq studies. WB:WBGene00046717 21ur-4785 No description available WB:WBGene00046718 21ur-4667 No description available WB:WBGene00046719 21ur-3472 No description available WB:WBGene00046720 21ur-3217 No description available WB:WBGene00046721 21ur-2513 No description available WB:WBGene00046722 21ur-4914 No description available WB:WBGene00046723 21ur-2531 No description available WB:WBGene00046724 21ur-486 No description available WB:WBGene00046725 21ur-4120 No description available WB:WBGene00046726 21ur-2422 No description available WB:WBGene00046727 21ur-3375 No description available WB:WBGene00046728 21ur-3977 No description available WB:WBGene00046729 21ur-3629 No description available WB:WBGene00046730 21ur-224 No description available WB:WBGene00046731 21ur-1030 No description available WB:WBGene00046732 21ur-4591 No description available WB:WBGene00046733 21ur-372 No description available WB:WBGene00046734 21ur-298 No description available WB:WBGene00046735 21ur-744 No description available WB:WBGene00046736 21ur-3465 Enriched in neurons based on RNA-seq studies. WB:WBGene00046737 21ur-4175 No description available WB:WBGene00046738 21ur-2667 No description available WB:WBGene00046739 21ur-2470 No description available WB:WBGene00046740 21ur-1447 No description available WB:WBGene00046741 21ur-1887 No description available WB:WBGene00046742 21ur-4643 No description available WB:WBGene00046743 21ur-5271 No description available WB:WBGene00046744 21ur-2411 No description available WB:WBGene00046745 21ur-4974 No description available WB:WBGene00046746 21ur-3293 No description available WB:WBGene00046747 21ur-1263 No description available WB:WBGene00046748 21ur-5059 No description available WB:WBGene00046749 21ur-3224 No description available WB:WBGene00046750 21ur-3604 No description available WB:WBGene00046751 21ur-3578 No description available WB:WBGene00046752 21ur-4398 No description available WB:WBGene00046753 21ur-1180 No description available WB:WBGene00046754 21ur-3657 No description available WB:WBGene00046755 21ur-4054 No description available WB:WBGene00046756 21ur-114 No description available WB:WBGene00046757 21ur-2882 No description available WB:WBGene00046758 21ur-4748 Enriched in neurons based on RNA-seq studies. WB:WBGene00046759 21ur-531 No description available WB:WBGene00046760 21ur-2623 No description available WB:WBGene00046761 21ur-5282 No description available WB:WBGene00046762 21ur-1513 No description available WB:WBGene00046763 21ur-140 No description available WB:WBGene00046764 21ur-126 No description available WB:WBGene00046765 21ur-3337 No description available WB:WBGene00046766 21ur-1028 No description available WB:WBGene00046767 21ur-444 No description available WB:WBGene00046768 21ur-1840 No description available WB:WBGene00046769 21ur-3272 No description available WB:WBGene00046770 21ur-1651 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00046771 21ur-2361 No description available WB:WBGene00046772 21ur-1346 No description available WB:WBGene00046773 21ur-453 No description available WB:WBGene00046774 21ur-4722 No description available WB:WBGene00046775 21ur-2066 No description available WB:WBGene00046776 21ur-3653 No description available WB:WBGene00046777 21ur-189 No description available WB:WBGene00046778 21ur-411 No description available WB:WBGene00046779 21ur-4069 No description available WB:WBGene00046780 21ur-5224 No description available WB:WBGene00046781 21ur-2614 No description available WB:WBGene00046782 21ur-773 No description available WB:WBGene00046783 21ur-47 No description available WB:WBGene00046784 21ur-3681 No description available WB:WBGene00046785 21ur-664 No description available WB:WBGene00046786 21ur-2992 No description available WB:WBGene00046787 21ur-611 No description available WB:WBGene00046788 21ur-5448 No description available WB:WBGene00046789 21ur-5127 No description available WB:WBGene00046790 21ur-2639 No description available WB:WBGene00046791 21ur-3288 No description available WB:WBGene00046792 21ur-1265 No description available WB:WBGene00046793 21ur-479 No description available WB:WBGene00046794 21ur-4270 No description available WB:WBGene00046795 21ur-428 No description available WB:WBGene00046796 21ur-2343 No description available WB:WBGene00046797 21ur-889 No description available WB:WBGene00046798 21ur-3100 No description available WB:WBGene00046799 21ur-4740 No description available WB:WBGene00046800 21ur-2752 No description available WB:WBGene00046801 21ur-5227 No description available WB:WBGene00046802 21ur-4520 Enriched in neurons based on RNA-seq studies. WB:WBGene00046803 21ur-5302 No description available WB:WBGene00046804 21ur-3011 No description available WB:WBGene00046805 21ur-2703 No description available WB:WBGene00046806 21ur-526 No description available WB:WBGene00046807 21ur-369 No description available WB:WBGene00046808 21ur-4826 Enriched in neurons based on RNA-seq studies. WB:WBGene00046809 21ur-306 No description available WB:WBGene00046810 21ur-1048 No description available WB:WBGene00046811 21ur-2687 No description available WB:WBGene00046812 21ur-4994 No description available WB:WBGene00046813 21ur-591 No description available WB:WBGene00046814 21ur-2282 No description available WB:WBGene00046815 21ur-2662 No description available WB:WBGene00046816 21ur-3571 No description available WB:WBGene00046817 21ur-2192 No description available WB:WBGene00046818 21ur-1864 No description available WB:WBGene00046819 21ur-2490 No description available WB:WBGene00046820 21ur-5207 No description available WB:WBGene00046821 21ur-2640 No description available WB:WBGene00046822 21ur-4727 No description available WB:WBGene00046823 21ur-3237 No description available WB:WBGene00046824 21ur-2423 No description available WB:WBGene00046825 21ur-1590 No description available WB:WBGene00046826 21ur-3729 No description available WB:WBGene00046827 21ur-3452 No description available WB:WBGene00046828 21ur-578 No description available WB:WBGene00046829 21ur-4186 No description available WB:WBGene00046830 21ur-3732 No description available WB:WBGene00046831 21ur-1873 No description available WB:WBGene00046832 21ur-534 No description available WB:WBGene00046833 21ur-3984 Is affected by ins-11 and xpf-1 based on RNA-seq studies. WB:WBGene00046834 21ur-2702 No description available WB:WBGene00046835 21ur-3169 No description available WB:WBGene00046836 21ur-794 No description available WB:WBGene00046837 21ur-2132 No description available WB:WBGene00046838 21ur-1000 No description available WB:WBGene00046839 21ur-3284 No description available WB:WBGene00046840 21ur-4542 No description available WB:WBGene00046841 21ur-1860 No description available WB:WBGene00046842 21ur-3354 No description available WB:WBGene00046843 21ur-2968 No description available WB:WBGene00046844 21ur-2024 No description available WB:WBGene00046845 21ur-3897 No description available WB:WBGene00046846 21ur-423 No description available WB:WBGene00046847 21ur-3887 No description available WB:WBGene00046848 21ur-68 No description available WB:WBGene00046849 21ur-273 No description available WB:WBGene00046850 21ur-3740 No description available WB:WBGene00046851 21ur-1919 No description available WB:WBGene00046852 21ur-4705 No description available WB:WBGene00046853 21ur-2934 No description available WB:WBGene00046854 21ur-1164 No description available WB:WBGene00046855 21ur-2296 No description available WB:WBGene00046856 21ur-4592 No description available WB:WBGene00046857 21ur-2680 No description available WB:WBGene00046858 21ur-628 No description available WB:WBGene00046859 21ur-4615 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00046860 21ur-4388 No description available WB:WBGene00046861 21ur-40 No description available WB:WBGene00046862 21ur-2875 No description available WB:WBGene00046863 21ur-1844 No description available WB:WBGene00046864 21ur-5052 Is affected by eat-2 based on microarray studies. WB:WBGene00046865 21ur-999 No description available WB:WBGene00046866 21ur-1235 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00046867 21ur-408 No description available WB:WBGene00046868 21ur-3027 No description available WB:WBGene00046869 21ur-2938 No description available WB:WBGene00046870 21ur-2236 No description available WB:WBGene00046871 21ur-2658 Enriched in neurons based on RNA-seq studies. WB:WBGene00046872 21ur-4739 No description available WB:WBGene00046873 21ur-3952 No description available WB:WBGene00046874 21ur-3492 No description available WB:WBGene00046875 21ur-103 Is affected by daf-2 based on microarray studies. WB:WBGene00046876 21ur-3941 No description available WB:WBGene00046877 21ur-1673 No description available WB:WBGene00046878 21ur-1225 No description available WB:WBGene00046879 21ur-2172 No description available WB:WBGene00046880 21ur-5054 No description available WB:WBGene00046881 21ur-969 No description available WB:WBGene00046882 21ur-5234 No description available WB:WBGene00046883 21ur-1135 No description available WB:WBGene00046884 21ur-1681 No description available WB:WBGene00046885 21ur-2292 Enriched in neurons based on RNA-seq studies. WB:WBGene00046886 21ur-2427 No description available WB:WBGene00046887 21ur-2678 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00046888 21ur-1342 No description available WB:WBGene00046889 21ur-215 No description available WB:WBGene00046890 21ur-5250 No description available WB:WBGene00046891 21ur-5089 No description available WB:WBGene00046892 21ur-4249 No description available WB:WBGene00046893 21ur-2160 No description available WB:WBGene00046894 21ur-2831 No description available WB:WBGene00046895 21ur-4302 No description available WB:WBGene00046896 21ur-870 No description available WB:WBGene00046897 21ur-2262 Enriched in neurons based on RNA-seq studies. WB:WBGene00046898 21ur-4987 No description available WB:WBGene00046899 21ur-1070 No description available WB:WBGene00046900 21ur-235 No description available WB:WBGene00046901 21ur-3612 No description available WB:WBGene00046902 21ur-1689 No description available WB:WBGene00046903 21ur-1292 No description available WB:WBGene00046904 21ur-3828 No description available WB:WBGene00046905 21ur-1397 No description available WB:WBGene00046906 21ur-4851 No description available WB:WBGene00046907 21ur-3868 No description available WB:WBGene00046908 21ur-5174 No description available WB:WBGene00046909 21ur-175 No description available WB:WBGene00046910 21ur-557 No description available WB:WBGene00046911 21ur-4274 No description available WB:WBGene00046912 21ur-582 Enriched in neurons based on RNA-seq studies. WB:WBGene00046913 21ur-725 No description available WB:WBGene00046914 21ur-821 No description available WB:WBGene00046915 21ur-2420 No description available WB:WBGene00046916 21ur-1505 No description available WB:WBGene00046917 21ur-4569 No description available WB:WBGene00046918 21ur-1099 No description available WB:WBGene00046919 21ur-2395 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00046920 21ur-603 No description available WB:WBGene00046921 21ur-2645 No description available WB:WBGene00046922 21ur-1477 No description available WB:WBGene00046923 21ur-4292 No description available WB:WBGene00046924 21ur-358 No description available WB:WBGene00046925 21ur-1462 No description available WB:WBGene00046926 21ur-4407 No description available WB:WBGene00046927 21ur-3260 No description available WB:WBGene00046928 21ur-2154 No description available WB:WBGene00046929 21ur-4576 No description available WB:WBGene00046930 21ur-1751 No description available WB:WBGene00046931 21ur-3195 No description available WB:WBGene00046932 21ur-2928 No description available WB:WBGene00046933 21ur-3607 Enriched in neurons based on RNA-seq studies. WB:WBGene00046934 21ur-5178 No description available WB:WBGene00046935 21ur-3088 No description available WB:WBGene00046936 21ur-169 No description available WB:WBGene00046937 21ur-4751 Enriched in neurons based on RNA-seq studies. WB:WBGene00046938 21ur-2126 No description available WB:WBGene00046939 21ur-4834 No description available WB:WBGene00046940 21ur-2538 No description available WB:WBGene00046941 21ur-3572 No description available WB:WBGene00046942 21ur-1910 Enriched in neurons based on RNA-seq studies. WB:WBGene00046943 21ur-750 No description available WB:WBGene00046944 21ur-1483 No description available WB:WBGene00046945 21ur-4452 No description available WB:WBGene00046946 21ur-2756 No description available WB:WBGene00046947 21ur-3940 Enriched in neurons based on RNA-seq studies. WB:WBGene00046948 21ur-2252 No description available WB:WBGene00046949 21ur-1102 No description available WB:WBGene00046950 21ur-1993 No description available WB:WBGene00046951 21ur-762 No description available WB:WBGene00046952 21ur-3936 No description available WB:WBGene00046953 21ur-1484 No description available WB:WBGene00046954 21ur-4524 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00046955 21ur-5105 No description available WB:WBGene00046956 21ur-260 No description available WB:WBGene00046957 21ur-4680 No description available WB:WBGene00046958 21ur-3108 No description available WB:WBGene00046959 21ur-607 No description available WB:WBGene00046960 21ur-3816 No description available WB:WBGene00046961 21ur-1564 No description available WB:WBGene00046962 21ur-2611 No description available WB:WBGene00046963 21ur-1367 No description available WB:WBGene00046964 21ur-2086 No description available WB:WBGene00046965 21ur-3665 No description available WB:WBGene00046966 21ur-4063 No description available WB:WBGene00046967 21ur-1466 No description available WB:WBGene00046968 21ur-201 No description available WB:WBGene00046969 21ur-868 No description available WB:WBGene00046970 21ur-1899 No description available WB:WBGene00046971 21ur-452 No description available WB:WBGene00046972 21ur-3094 No description available WB:WBGene00046973 21ur-1682 No description available WB:WBGene00046974 21ur-469 Enriched in neurons based on RNA-seq studies. WB:WBGene00046975 21ur-4501 No description available WB:WBGene00046976 21ur-1400 No description available WB:WBGene00046977 21ur-698 No description available WB:WBGene00046978 21ur-75 Enriched in neurons based on RNA-seq studies. WB:WBGene00046979 21ur-1522 No description available WB:WBGene00046980 21ur-1619 No description available WB:WBGene00046981 21ur-3003 No description available WB:WBGene00046982 21ur-5339 No description available WB:WBGene00046983 21ur-4353 No description available WB:WBGene00046984 21ur-3121 No description available WB:WBGene00046985 21ur-1176 No description available WB:WBGene00046986 21ur-2685 No description available WB:WBGene00046987 21ur-1312 No description available WB:WBGene00046988 21ur-4190 No description available WB:WBGene00046989 21ur-3349 No description available WB:WBGene00046990 21ur-5236 No description available WB:WBGene00046991 21ur-2787 No description available WB:WBGene00046992 21ur-3586 No description available WB:WBGene00046993 21ur-5144 Enriched in neurons based on RNA-seq studies. WB:WBGene00046994 21ur-2977 No description available WB:WBGene00046995 21ur-3473 No description available WB:WBGene00046996 21ur-52 No description available WB:WBGene00046997 21ur-153 No description available WB:WBGene00046998 21ur-4466 No description available WB:WBGene00046999 21ur-2828 No description available WB:WBGene00047000 21ur-5259 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00047001 21ur-681 No description available WB:WBGene00047002 21ur-1450 No description available WB:WBGene00047003 21ur-988 Enriched in neurons based on RNA-seq studies. WB:WBGene00047004 21ur-2567 No description available WB:WBGene00047005 21ur-571 No description available WB:WBGene00047006 21ur-3783 No description available WB:WBGene00047007 21ur-284 No description available WB:WBGene00047008 21ur-2358 No description available WB:WBGene00047009 21ur-24 No description available WB:WBGene00047010 21ur-3593 No description available WB:WBGene00047011 21ur-4337 No description available WB:WBGene00047012 21ur-5364 No description available WB:WBGene00047013 21ur-4684 No description available WB:WBGene00047014 21ur-4589 No description available WB:WBGene00047015 21ur-438 No description available WB:WBGene00047016 21ur-4664 No description available WB:WBGene00047017 21ur-3636 No description available WB:WBGene00047018 21ur-854 No description available WB:WBGene00047019 21ur-2902 No description available WB:WBGene00047020 21ur-4325 No description available WB:WBGene00047021 21ur-108 No description available WB:WBGene00047022 21ur-4342 No description available WB:WBGene00047023 21ur-908 No description available WB:WBGene00047024 21ur-3958 No description available WB:WBGene00047025 21ur-4391 No description available WB:WBGene00047026 21ur-2415 No description available WB:WBGene00047027 21ur-3600 No description available WB:WBGene00047028 21ur-4825 No description available WB:WBGene00047029 21ur-1375 No description available WB:WBGene00047030 21ur-2167 No description available WB:WBGene00047031 21ur-1039 No description available WB:WBGene00047032 21ur-3924 No description available WB:WBGene00047033 21ur-5110 No description available WB:WBGene00047034 21ur-5279 No description available WB:WBGene00047035 21ur-2591 No description available WB:WBGene00047036 21ur-2578 No description available WB:WBGene00047037 21ur-5166 No description available WB:WBGene00047038 21ur-2182 No description available WB:WBGene00047039 21ur-1767 Enriched in neurons based on RNA-seq studies. WB:WBGene00047040 21ur-5420 No description available WB:WBGene00047041 21ur-4815 No description available WB:WBGene00047042 21ur-3530 No description available WB:WBGene00047043 21ur-1043 No description available WB:WBGene00047044 21ur-4758 No description available WB:WBGene00047045 21ur-196 No description available WB:WBGene00047046 21ur-775 No description available WB:WBGene00047047 21ur-3067 No description available WB:WBGene00047048 21ur-1608 No description available WB:WBGene00047049 21ur-4608 No description available WB:WBGene00047050 21ur-1046 No description available WB:WBGene00047051 21ur-1319 No description available WB:WBGene00047052 21ur-2215 No description available WB:WBGene00047053 21ur-594 No description available WB:WBGene00047054 21ur-4030 No description available WB:WBGene00047055 21ur-5432 No description available WB:WBGene00047056 21ur-1732 No description available WB:WBGene00047057 21ur-1244 Enriched in neurons based on RNA-seq studies. WB:WBGene00047058 21ur-5111 No description available WB:WBGene00047059 21ur-4945 No description available WB:WBGene00047060 21ur-4182 No description available WB:WBGene00047061 21ur-818 No description available WB:WBGene00047062 21ur-2774 No description available WB:WBGene00047063 21ur-3537 No description available WB:WBGene00047064 21ur-5019 No description available WB:WBGene00047065 21ur-503 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00047066 21ur-3146 No description available WB:WBGene00047067 21ur-123 Enriched in neurons based on RNA-seq studies. WB:WBGene00047068 21ur-808 No description available WB:WBGene00047069 21ur-1131 No description available WB:WBGene00047070 21ur-2012 Enriched in neurons based on RNA-seq studies. WB:WBGene00047071 21ur-3973 No description available WB:WBGene00047072 21ur-994 No description available WB:WBGene00047073 21ur-5037 No description available WB:WBGene00047074 21ur-2714 No description available WB:WBGene00047075 21ur-1362 No description available WB:WBGene00047076 21ur-596 No description available WB:WBGene00047077 21ur-4670 No description available WB:WBGene00047078 21ur-1497 No description available WB:WBGene00047079 21ur-4902 No description available WB:WBGene00047080 21ur-3981 No description available WB:WBGene00047081 21ur-4209 No description available WB:WBGene00047082 21ur-2161 No description available WB:WBGene00047083 21ur-5196 No description available WB:WBGene00047084 21ur-5028 No description available WB:WBGene00047085 21ur-3311 No description available WB:WBGene00047086 21ur-4536 No description available WB:WBGene00047087 21ur-382 No description available WB:WBGene00047088 21ur-5263 Enriched in neurons based on RNA-seq studies. WB:WBGene00047089 21ur-1360 No description available WB:WBGene00047090 21ur-3447 No description available WB:WBGene00047091 21ur-1352 No description available WB:WBGene00047092 21ur-2909 No description available WB:WBGene00047093 21ur-4786 No description available WB:WBGene00047094 21ur-3432 No description available WB:WBGene00047095 21ur-2304 No description available WB:WBGene00047096 21ur-2892 No description available WB:WBGene00047097 21ur-836 No description available WB:WBGene00047098 21ur-1937 No description available WB:WBGene00047099 21ur-2541 No description available WB:WBGene00047100 21ur-4513 No description available WB:WBGene00047101 21ur-2874 No description available WB:WBGene00047102 21ur-5094 No description available WB:WBGene00047103 21ur-4888 No description available WB:WBGene00047104 21ur-4043 No description available WB:WBGene00047105 21ur-1118 No description available WB:WBGene00047106 21ur-3073 No description available WB:WBGene00047107 21ur-5446 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00047108 21ur-2117 No description available WB:WBGene00047109 21ur-564 No description available WB:WBGene00047110 21ur-2598 No description available WB:WBGene00047111 21ur-2984 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00047112 21ur-5325 No description available WB:WBGene00047113 21ur-1555 No description available WB:WBGene00047114 21ur-1204 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00047115 21ur-4794 No description available WB:WBGene00047116 21ur-3173 No description available WB:WBGene00047117 21ur-20 No description available WB:WBGene00047118 21ur-1210 No description available WB:WBGene00047119 21ur-3457 No description available WB:WBGene00047120 21ur-892 No description available WB:WBGene00047121 21ur-2517 No description available WB:WBGene00047122 21ur-4144 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00047123 21ur-1327 No description available WB:WBGene00047124 21ur-5008 No description available WB:WBGene00047125 21ur-1871 No description available WB:WBGene00047126 21ur-4172 No description available WB:WBGene00047127 21ur-3000 No description available WB:WBGene00047128 21ur-365 No description available WB:WBGene00047129 21ur-3282 No description available WB:WBGene00047130 21ur-1301 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00047131 21ur-5401 No description available WB:WBGene00047132 21ur-1601 No description available WB:WBGene00047133 21ur-1054 No description available WB:WBGene00047134 21ur-11 No description available WB:WBGene00047135 21ur-3183 No description available WB:WBGene00047136 21ur-3656 No description available WB:WBGene00047137 21ur-2098 No description available WB:WBGene00047138 21ur-1770 No description available WB:WBGene00047139 21ur-647 No description available WB:WBGene00047140 21ur-3860 No description available WB:WBGene00047141 21ur-2369 No description available WB:WBGene00047142 21ur-2005 No description available WB:WBGene00047143 21ur-1905 No description available WB:WBGene00047144 21ur-1109 No description available WB:WBGene00047145 21ur-4215 No description available WB:WBGene00047146 21ur-4133 No description available WB:WBGene00047147 21ur-3371 No description available WB:WBGene00047148 21ur-2930 No description available WB:WBGene00047149 21ur-4546 No description available WB:WBGene00047150 21ur-3833 No description available WB:WBGene00047151 21ur-2390 No description available WB:WBGene00047152 21ur-2956 No description available WB:WBGene00047153 21ur-2744 No description available WB:WBGene00047154 21ur-3648 No description available WB:WBGene00047155 21ur-1984 No description available WB:WBGene00047156 21ur-3081 No description available WB:WBGene00047157 21ur-925 No description available WB:WBGene00047158 21ur-3515 No description available WB:WBGene00047159 21ur-4968 No description available WB:WBGene00047160 21ur-5314 No description available WB:WBGene00047161 21ur-3305 No description available WB:WBGene00047162 21ur-5454 No description available WB:WBGene00047163 21ur-2554 No description available WB:WBGene00047164 21ur-5275 No description available WB:WBGene00047165 21ur-1085 No description available WB:WBGene00047166 21ur-376 No description available WB:WBGene00047167 21ur-3130 No description available WB:WBGene00047168 21ur-1598 No description available WB:WBGene00047169 21ur-2158 Is affected by several genes including lem-2; emr-1; and damt-1 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00047170 21ur-1761 No description available WB:WBGene00047171 21ur-1369 No description available WB:WBGene00047172 21ur-3620 No description available WB:WBGene00047173 21ur-623 No description available WB:WBGene00047174 21ur-4801 No description available WB:WBGene00047175 21ur-4927 No description available WB:WBGene00047176 21ur-991 No description available WB:WBGene00047177 21ur-1704 No description available WB:WBGene00047178 21ur-702 No description available WB:WBGene00047179 21ur-689 No description available WB:WBGene00047180 21ur-2921 Is affected by eat-2 based on microarray studies. WB:WBGene00047181 21ur-5156 No description available WB:WBGene00047182 21ur-4003 No description available WB:WBGene00047183 21ur-3855 No description available WB:WBGene00047184 21ur-1259 No description available WB:WBGene00047185 21ur-336 Enriched in neurons based on RNA-seq studies. WB:WBGene00047186 21ur-312 No description available WB:WBGene00047187 21ur-5430 No description available WB:WBGene00047188 21ur-622 Enriched in neurons based on RNA-seq studies. WB:WBGene00047189 21ur-2255 No description available WB:WBGene00047190 21ur-2710 No description available WB:WBGene00047191 21ur-615 Enriched in neurons based on RNA-seq studies. WB:WBGene00047192 21ur-1276 No description available WB:WBGene00047193 21ur-1076 No description available WB:WBGene00047194 21ur-4307 No description available WB:WBGene00047195 21ur-5293 No description available WB:WBGene00047196 21ur-294 No description available WB:WBGene00047197 21ur-5335 No description available WB:WBGene00047198 21ur-1742 No description available WB:WBGene00047199 21ur-3699 No description available WB:WBGene00047200 21ur-5212 No description available WB:WBGene00047201 21ur-2205 No description available WB:WBGene00047202 21ur-4714 No description available WB:WBGene00047203 21ur-228 No description available WB:WBGene00047204 21ur-2371 No description available WB:WBGene00047205 21ur-1749 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00047206 21ur-2698 No description available WB:WBGene00047207 21ur-3512 No description available WB:WBGene00047208 21ur-320 No description available WB:WBGene00047209 21ur-267 No description available WB:WBGene00047210 21ur-1431 No description available WB:WBGene00047211 21ur-785 No description available WB:WBGene00047212 21ur-655 No description available WB:WBGene00047213 21ur-4233 No description available WB:WBGene00047214 21ur-1309 No description available WB:WBGene00047215 21ur-2360 No description available WB:WBGene00047216 21ur-1692 No description available WB:WBGene00047217 21ur-2060 No description available WB:WBGene00047218 21ur-3330 No description available WB:WBGene00047219 21ur-5383 No description available WB:WBGene00047220 21ur-5187 No description available WB:WBGene00047221 21ur-3216 No description available WB:WBGene00047222 21ur-1975 No description available WB:WBGene00047223 21ur-230 No description available WB:WBGene00047224 21ur-496 No description available WB:WBGene00047225 21ur-3043 Enriched in neurons based on RNA-seq studies. WB:WBGene00047226 21ur-3322 No description available WB:WBGene00047227 21ur-4482 No description available WB:WBGene00047228 21ur-4700 No description available WB:WBGene00047229 21ur-4421 No description available WB:WBGene00047230 21ur-5071 No description available WB:WBGene00047231 21ur-4228 No description available WB:WBGene00047232 21ur-5184 Is affected by set-2 based on RNA-seq studies. WB:WBGene00047233 21ur-4118 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00047234 21ur-4874 No description available WB:WBGene00047235 21ur-2295 No description available WB:WBGene00047236 21ur-3882 No description available WB:WBGene00047237 21ur-1040 No description available WB:WBGene00047238 21ur-5206 No description available WB:WBGene00047239 21ur-2261 No description available WB:WBGene00047240 21ur-4523 No description available WB:WBGene00047241 21ur-2284 No description available WB:WBGene00047242 21ur-109 No description available WB:WBGene00047243 21ur-3706 No description available WB:WBGene00047244 21ur-2622 No description available WB:WBGene00047245 21ur-2933 No description available WB:WBGene00047246 21ur-4090 No description available WB:WBGene00047247 21ur-2699 No description available WB:WBGene00047248 21ur-5419 No description available WB:WBGene00047249 21ur-2270 No description available WB:WBGene00047250 21ur-33 No description available WB:WBGene00047251 21ur-4284 No description available WB:WBGene00047252 21ur-3353 No description available WB:WBGene00047253 21ur-3232 No description available WB:WBGene00047254 21ur-1230 Is affected by daf-2 based on microarray studies. WB:WBGene00047255 21ur-216 No description available WB:WBGene00047256 21ur-2691 No description available WB:WBGene00047257 21ur-1965 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00047258 21ur-1075 No description available WB:WBGene00047259 21ur-3329 No description available WB:WBGene00047260 21ur-346 Enriched in neurons based on RNA-seq studies. WB:WBGene00047261 21ur-4926 No description available WB:WBGene00047262 21ur-2078 No description available WB:WBGene00047263 21ur-1158 No description available WB:WBGene00047264 21ur-406 No description available WB:WBGene00047265 21ur-1694 No description available WB:WBGene00047266 21ur-327 No description available WB:WBGene00047267 21ur-2173 No description available WB:WBGene00047268 21ur-1810 No description available WB:WBGene00047269 21ur-2559 No description available WB:WBGene00047270 21ur-2736 Is affected by several genes including hpl-2; mrps-5; and hmg-4 based on RNA-seq studies. WB:WBGene00047271 21ur-3225 No description available WB:WBGene00047272 21ur-1217 No description available WB:WBGene00047273 21ur-4848 No description available WB:WBGene00047274 21ur-3493 No description available WB:WBGene00047275 21ur-4093 No description available WB:WBGene00047276 21ur-1448 No description available WB:WBGene00047277 21ur-3218 No description available WB:WBGene00047278 21ur-4260 No description available WB:WBGene00047279 21ur-985 No description available WB:WBGene00047280 21ur-5216 No description available WB:WBGene00047281 21ur-5334 No description available WB:WBGene00047282 21ur-1444 No description available WB:WBGene00047283 21ur-2911 No description available WB:WBGene00047284 21ur-4917 No description available WB:WBGene00047285 21ur-143 No description available WB:WBGene00047286 21ur-2967 No description available WB:WBGene00047287 21ur-5374 No description available WB:WBGene00047288 21ur-1243 No description available WB:WBGene00047289 21ur-2636 No description available WB:WBGene00047290 21ur-993 No description available WB:WBGene00047291 21ur-1756 No description available WB:WBGene00047292 21ur-1716 No description available WB:WBGene00047293 21ur-4028 No description available WB:WBGene00047294 21ur-1603 No description available WB:WBGene00047295 21ur-4073 No description available WB:WBGene00047296 21ur-4531 No description available WB:WBGene00047297 21ur-3462 No description available WB:WBGene00047298 21ur-2064 No description available WB:WBGene00047299 21ur-3652 No description available WB:WBGene00047300 21ur-1514 No description available WB:WBGene00047301 21ur-3021 No description available WB:WBGene00047302 21ur-3390 No description available WB:WBGene00047303 21ur-2757 No description available WB:WBGene00047304 21ur-3273 No description available WB:WBGene00047305 21ur-4774 Is affected by daf-2 based on microarray studies. WB:WBGene00047306 21ur-286 No description available WB:WBGene00047307 21ur-1411 No description available WB:WBGene00047308 21ur-1268 No description available WB:WBGene00047309 21ur-1183 No description available WB:WBGene00047310 21ur-2019 No description available WB:WBGene00047311 21ur-743 No description available WB:WBGene00047312 21ur-4445 Enriched in neurons based on RNA-seq studies. WB:WBGene00047313 21ur-2601 No description available WB:WBGene00047314 21ur-483 No description available WB:WBGene00047315 21ur-835 No description available WB:WBGene00047316 21ur-1237 No description available WB:WBGene00047317 21ur-3056 No description available WB:WBGene00047318 21ur-4723 No description available WB:WBGene00047319 21ur-1474 No description available WB:WBGene00047320 21ur-1536 No description available WB:WBGene00047321 21ur-3418 No description available WB:WBGene00047322 21ur-4373 No description available WB:WBGene00047323 21ur-953 No description available WB:WBGene00047324 21ur-2339 No description available WB:WBGene00047325 21ur-2679 No description available WB:WBGene00047326 21ur-4876 No description available WB:WBGene00047327 21ur-53 No description available WB:WBGene00047328 21ur-3017 No description available WB:WBGene00047329 21ur-4601 No description available WB:WBGene00047330 21ur-1112 No description available WB:WBGene00047331 21ur-2998 No description available WB:WBGene00047332 21ur-88 No description available WB:WBGene00047333 21ur-974 No description available WB:WBGene00047334 21ur-1870 No description available WB:WBGene00047335 21ur-867 No description available WB:WBGene00047336 21ur-2993 No description available WB:WBGene00047337 21ur-3289 No description available WB:WBGene00047338 21ur-2291 No description available WB:WBGene00047339 21ur-3628 No description available WB:WBGene00047340 21ur-429 No description available WB:WBGene00047341 21ur-5283 No description available WB:WBGene00047342 21ur-3754 No description available WB:WBGene00047343 21ur-1181 No description available WB:WBGene00047344 21ur-3285 Enriched in neurons based on RNA-seq studies. WB:WBGene00047345 21ur-5309 No description available WB:WBGene00047346 21ur-2264 No description available WB:WBGene00047347 21ur-2246 No description available WB:WBGene00047348 21ur-3320 No description available WB:WBGene00047349 21ur-420 No description available WB:WBGene00047350 21ur-3962 No description available WB:WBGene00047351 21ur-2310 No description available WB:WBGene00047352 21ur-3805 No description available WB:WBGene00047353 21ur-1879 No description available WB:WBGene00047354 21ur-478 No description available WB:WBGene00047355 21ur-886 No description available WB:WBGene00047356 21ur-4472 No description available WB:WBGene00047357 21ur-665 No description available WB:WBGene00047358 21ur-1739 No description available WB:WBGene00047359 21ur-2635 No description available WB:WBGene00047360 21ur-2332 No description available WB:WBGene00047361 21ur-4145 Enriched in neurons based on RNA-seq studies. WB:WBGene00047362 21ur-124 No description available WB:WBGene00047363 21ur-1347 No description available WB:WBGene00047364 21ur-4975 No description available WB:WBGene00047365 21ur-3724 No description available WB:WBGene00047366 21ur-3168 No description available WB:WBGene00047367 21ur-928 No description available WB:WBGene00047368 21ur-4726 No description available WB:WBGene00047369 21ur-4191 No description available WB:WBGene00047370 21ur-3368 No description available WB:WBGene00047371 21ur-1927 No description available WB:WBGene00047372 21ur-4650 No description available WB:WBGene00047373 21ur-246 No description available WB:WBGene00047374 21ur-1223 No description available WB:WBGene00047375 21ur-4202 No description available WB:WBGene00047376 21ur-1065 No description available WB:WBGene00047377 21ur-3405 No description available WB:WBGene00047378 21ur-2481 No description available WB:WBGene00047379 21ur-465 No description available WB:WBGene00047380 21ur-539 No description available WB:WBGene00047381 21ur-2041 No description available WB:WBGene00047382 21ur-254 No description available WB:WBGene00047383 21ur-4493 No description available WB:WBGene00047384 21ur-2790 No description available WB:WBGene00047385 21ur-2111 No description available WB:WBGene00047386 21ur-1855 No description available WB:WBGene00047387 21ur-1943 No description available WB:WBGene00047388 21ur-2404 No description available WB:WBGene00047389 21ur-4324 Enriched in neurons based on RNA-seq studies. WB:WBGene00047390 21ur-2959 No description available WB:WBGene00047391 21ur-1902 No description available WB:WBGene00047392 21ur-5402 No description available WB:WBGene00047393 21ur-3318 No description available WB:WBGene00047394 21ur-255 No description available WB:WBGene00047395 21ur-3348 No description available WB:WBGene00047396 21ur-525 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00047397 21ur-3733 No description available WB:WBGene00047398 21ur-2766 Enriched in neurons based on RNA-seq studies. WB:WBGene00047399 21ur-3672 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00047400 21ur-4952 No description available WB:WBGene00047401 21ur-1911 No description available WB:WBGene00047402 21ur-4242 No description available WB:WBGene00047403 21ur-4111 No description available WB:WBGene00047404 21ur-3579 No description available WB:WBGene00047405 21ur-639 No description available WB:WBGene00047406 21ur-4593 No description available WB:WBGene00047407 21ur-2830 No description available WB:WBGene00047408 21ur-4016 No description available WB:WBGene00047409 21ur-2451 No description available WB:WBGene00047410 21ur-3710 No description available WB:WBGene00047411 21ur-1124 No description available WB:WBGene00047412 21ur-695 No description available WB:WBGene00047413 21ur-4267 No description available WB:WBGene00047414 21ur-4479 No description available WB:WBGene00047415 21ur-3204 No description available WB:WBGene00047416 21ur-2042 No description available WB:WBGene00047417 21ur-3356 No description available WB:WBGene00047418 21ur-160 No description available WB:WBGene00047419 21ur-4390 No description available WB:WBGene00047420 21ur-3251 No description available WB:WBGene00047421 21ur-3248 No description available WB:WBGene00047422 21ur-5192 No description available WB:WBGene00047423 21ur-3411 No description available WB:WBGene00047424 21ur-2208 No description available WB:WBGene00047425 21ur-3034 No description available WB:WBGene00047426 21ur-2328 No description available WB:WBGene00047427 21ur-3744 No description available WB:WBGene00047428 21ur-5046 No description available WB:WBGene00047429 21ur-1797 No description available WB:WBGene00047430 21ur-181 No description available WB:WBGene00047431 21ur-1170 No description available WB:WBGene00047432 21ur-2655 No description available WB:WBGene00047433 21ur-3567 No description available WB:WBGene00047434 21ur-2807 No description available WB:WBGene00047435 21ur-2976 No description available WB:WBGene00047436 21ur-936 No description available WB:WBGene00047437 21ur-1299 No description available WB:WBGene00047438 21ur-2589 No description available WB:WBGene00047439 21ur-387 No description available WB:WBGene00047440 21ur-468 No description available WB:WBGene00047441 21ur-2592 No description available WB:WBGene00047442 21ur-3244 No description available WB:WBGene00047443 21ur-3829 No description available WB:WBGene00047444 21ur-3953 Enriched in neurons based on RNA-seq studies. WB:WBGene00047445 21ur-1336 No description available WB:WBGene00047446 21ur-2780 No description available WB:WBGene00047447 21ur-471 No description available WB:WBGene00047448 21ur-4646 No description available WB:WBGene00047449 21ur-413 Enriched in neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00047450 21ur-3773 No description available WB:WBGene00047451 21ur-4108 No description available WB:WBGene00047452 21ur-3738 No description available WB:WBGene00047453 21ur-802 No description available WB:WBGene00047454 21ur-4671 No description available WB:WBGene00047455 21ur-3386 No description available WB:WBGene00047456 21ur-1721 No description available WB:WBGene00047457 21ur-961 No description available WB:WBGene00047458 21ur-3026 No description available WB:WBGene00047459 21ur-2465 No description available WB:WBGene00047460 21ur-4467 No description available WB:WBGene00047461 21ur-1665 No description available WB:WBGene00047462 21ur-2795 No description available WB:WBGene00047463 21ur-4614 Is affected by eat-2 based on microarray studies. WB:WBGene00047464 21ur-4383 No description available WB:WBGene00047465 21ur-1956 No description available WB:WBGene00047466 21ur-1676 No description available WB:WBGene00047467 21ur-2426 No description available WB:WBGene00047468 21ur-29 No description available WB:WBGene00047469 21ur-5292 No description available WB:WBGene00047470 21ur-4435 No description available WB:WBGene00047471 21ur-990 No description available WB:WBGene00047472 21ur-3129 No description available WB:WBGene00047473 21ur-135 No description available WB:WBGene00047474 21ur-4101 No description available WB:WBGene00047475 21ur-4440 No description available WB:WBGene00047476 21ur-1644 No description available WB:WBGene00047477 21ur-4314 No description available WB:WBGene00047478 21ur-69 No description available WB:WBGene00047479 21ur-4123 No description available WB:WBGene00047480 21ur-2514 No description available WB:WBGene00047481 21ur-1924 No description available WB:WBGene00047482 21ur-4152 No description available WB:WBGene00047483 21ur-1370 No description available WB:WBGene00047484 21ur-3711 No description available WB:WBGene00047485 21ur-3445 No description available WB:WBGene00047486 21ur-4802 No description available WB:WBGene00047487 21ur-913 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00047488 21ur-5449 No description available WB:WBGene00047489 21ur-2493 No description available WB:WBGene00047490 21ur-3688 No description available WB:WBGene00047491 21ur-5396 No description available WB:WBGene00047492 21ur-772 No description available WB:WBGene00047493 21ur-2146 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00047494 21ur-433 No description available WB:WBGene00047495 21ur-78 No description available WB:WBGene00047496 21ur-3664 No description available WB:WBGene00047497 21ur-4053 No description available WB:WBGene00047498 21ur-1090 Enriched in neurons based on RNA-seq studies. WB:WBGene00047499 21ur-3762 No description available WB:WBGene00047500 21ur-4510 Enriched in neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00047501 21ur-751 No description available WB:WBGene00047502 21ur-2650 No description available WB:WBGene00047503 21ur-3906 No description available WB:WBGene00047504 21ur-1824 No description available WB:WBGene00047505 21ur-4000 No description available WB:WBGene00047506 21ur-850 No description available WB:WBGene00047507 21ur-125 No description available WB:WBGene00047508 21ur-1253 No description available WB:WBGene00047509 21ur-542 Enriched in neurons based on RNA-seq studies. WB:WBGene00047510 21ur-2800 No description available WB:WBGene00047511 21ur-518 No description available WB:WBGene00047512 21ur-2253 No description available WB:WBGene00047513 21ur-1884 No description available WB:WBGene00047514 21ur-1589 No description available WB:WBGene00047515 21ur-1786 No description available WB:WBGene00047516 21ur-4743 No description available WB:WBGene00047517 21ur-575 No description available WB:WBGene00047518 21ur-617 No description available WB:WBGene00047519 21ur-3523 No description available WB:WBGene00047520 21ur-948 No description available WB:WBGene00047521 21ur-3362 No description available WB:WBGene00047522 21ur-1839 No description available WB:WBGene00047523 21ur-799 No description available WB:WBGene00047524 21ur-2059 No description available WB:WBGene00047525 21ur-516 No description available WB:WBGene00047526 21ur-1470 No description available WB:WBGene00047527 21ur-85 No description available WB:WBGene00047528 21ur-2566 No description available WB:WBGene00047529 21ur-2861 No description available WB:WBGene00047530 21ur-4500 No description available WB:WBGene00047531 21ur-2889 No description available WB:WBGene00047532 21ur-1523 No description available WB:WBGene00047533 21ur-1169 No description available WB:WBGene00047534 21ur-455 No description available WB:WBGene00047535 21ur-3122 No description available WB:WBGene00047536 21ur-2797 No description available WB:WBGene00047537 21ur-5353 No description available WB:WBGene00047538 21ur-2586 No description available WB:WBGene00047539 21ur-490 No description available WB:WBGene00047540 21ur-2459 No description available WB:WBGene00047541 21ur-4020 No description available WB:WBGene00047542 21ur-3095 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00047543 21ur-5107 No description available WB:WBGene00047544 21ur-4147 No description available WB:WBGene00047545 21ur-2741 No description available WB:WBGene00047546 21ur-677 No description available WB:WBGene00047547 21ur-5273 No description available WB:WBGene00047548 21ur-3242 No description available WB:WBGene00047549 21ur-349 No description available WB:WBGene00047550 21ur-2969 No description available WB:WBGene00047551 21ur-2135 No description available WB:WBGene00047552 21ur-2099 No description available WB:WBGene00047553 21ur-4350 No description available WB:WBGene00047554 21ur-2416 No description available WB:WBGene00047555 21ur-3585 No description available WB:WBGene00047556 21ur-5281 No description available WB:WBGene00047557 21ur-2669 No description available WB:WBGene00047558 21ur-2822 No description available WB:WBGene00047559 21ur-3806 No description available WB:WBGene00047560 21ur-3219 No description available WB:WBGene00047561 21ur-3080 Enriched in neurons based on RNA-seq studies. WB:WBGene00047562 21ur-4953 No description available WB:WBGene00047563 21ur-4594 No description available WB:WBGene00047564 21ur-767 No description available WB:WBGene00047565 21ur-4456 No description available WB:WBGene00047566 21ur-1372 Is affected by mrpl-2 based on RNA-seq studies. WB:WBGene00047567 21ur-987 No description available WB:WBGene00047568 21ur-1403 No description available WB:WBGene00047569 21ur-2929 No description available WB:WBGene00047570 21ur-2467 No description available WB:WBGene00047571 21ur-370 No description available WB:WBGene00047572 21ur-2436 Enriched in neurons based on RNA-seq studies. WB:WBGene00047573 21ur-4828 No description available WB:WBGene00047574 21ur-4336 No description available WB:WBGene00047575 21ur-1618 No description available WB:WBGene00047576 21ur-2621 No description available WB:WBGene00047577 21ur-49 No description available WB:WBGene00047578 21ur-926 No description available WB:WBGene00047579 21ur-5143 No description available WB:WBGene00047580 21ur-283 No description available WB:WBGene00047581 21ur-2546 No description available WB:WBGene00047582 21ur-1013 No description available WB:WBGene00047583 21ur-154 No description available WB:WBGene00047584 21ur-2759 No description available WB:WBGene00047585 21ur-5365 No description available WB:WBGene00047586 21ur-1086 No description available WB:WBGene00047587 21ur-1738 No description available WB:WBGene00047588 21ur-1378 No description available WB:WBGene00047589 21ur-2181 No description available WB:WBGene00047590 21ur-980 No description available WB:WBGene00047591 21ur-2180 No description available WB:WBGene00047592 21ur-551 No description available WB:WBGene00047593 21ur-176 No description available WB:WBGene00047594 21ur-335 No description available WB:WBGene00047595 21ur-5356 Is affected by meg-3 and meg-4 based on RNA-seq studies. WB:WBGene00047596 21ur-4339 No description available WB:WBGene00047597 21ur-162 No description available WB:WBGene00047598 21ur-2140 No description available WB:WBGene00047599 21ur-855 No description available WB:WBGene00047600 21ur-4683 No description available WB:WBGene00047601 21ur-3055 No description available WB:WBGene00047602 21ur-268 No description available WB:WBGene00047603 21ur-5421 No description available WB:WBGene00047604 21ur-900 No description available WB:WBGene00047605 21ur-1226 No description available WB:WBGene00047606 21ur-956 No description available WB:WBGene00047607 21ur-5211 No description available WB:WBGene00047608 21ur-537 No description available WB:WBGene00047609 21ur-3959 No description available WB:WBGene00047610 21ur-697 No description available WB:WBGene00047611 21ur-232 No description available WB:WBGene00047612 21ur-5326 No description available WB:WBGene00047613 21ur-560 No description available WB:WBGene00047614 21ur-214 No description available WB:WBGene00047615 21ur-4038 No description available WB:WBGene00047616 21ur-3844 No description available WB:WBGene00047617 21ur-558 No description available WB:WBGene00047618 21ur-3317 Enriched in neurons based on RNA-seq studies. WB:WBGene00047619 21ur-357 No description available WB:WBGene00047620 21ur-4255 No description available WB:WBGene00047621 21ur-763 No description available WB:WBGene00047622 21ur-4049 No description available WB:WBGene00047623 21ur-717 No description available WB:WBGene00047624 21ur-4568 No description available WB:WBGene00047625 21ur-739 No description available WB:WBGene00047626 21ur-616 No description available WB:WBGene00047627 21ur-5173 No description available WB:WBGene00047628 21ur-3592 No description available WB:WBGene00047629 21ur-95 No description available WB:WBGene00047630 21ur-1741 No description available WB:WBGene00047631 21ur-608 Is affected by eat-2 based on microarray studies. WB:WBGene00047632 21ur-703 No description available WB:WBGene00047633 21ur-5076 No description available WB:WBGene00047634 21ur-4408 No description available WB:WBGene00047635 21ur-2387 No description available WB:WBGene00047636 21ur-5120 No description available WB:WBGene00047637 21ur-1496 No description available WB:WBGene00047638 21ur-643 No description available WB:WBGene00047639 21ur-4052 No description available WB:WBGene00047640 21ur-4750 No description available WB:WBGene00047641 21ur-367 No description available WB:WBGene00047642 21ur-439 No description available WB:WBGene00047643 21ur-809 No description available WB:WBGene00047644 21ur-581 No description available WB:WBGene00047645 21ur-3986 No description available WB:WBGene00047646 21ur-4275 No description available WB:WBGene00047647 21ur-2884 No description available WB:WBGene00047648 21ur-5426 No description available WB:WBGene00047649 21ur-2089 No description available WB:WBGene00047650 21ur-1994 No description available WB:WBGene00047651 21ur-3615 No description available WB:WBGene00047652 21ur-2503 No description available WB:WBGene00047653 21ur-1436 No description available WB:WBGene00047654 21ur-4707 No description available WB:WBGene00047655 21ur-445 No description available WB:WBGene00047656 21ur-477 Enriched in neurons based on RNA-seq studies. WB:WBGene00047657 21ur-3666 Enriched in neurons based on RNA-seq studies. WB:WBGene00047658 21ur-42 No description available WB:WBGene00047659 21ur-4579 No description available WB:WBGene00047660 21ur-1016 No description available WB:WBGene00047661 21ur-5177 No description available WB:WBGene00047662 21ur-100 No description available WB:WBGene00047663 21ur-3935 No description available WB:WBGene00047664 21ur-1291 No description available WB:WBGene00047665 21ur-1713 No description available WB:WBGene00047666 21ur-93 No description available WB:WBGene00047667 21ur-1463 No description available WB:WBGene00047668 21ur-3573 No description available WB:WBGene00047669 21ur-220 No description available WB:WBGene00047670 21ur-113 Enriched in neurons based on RNA-seq studies. WB:WBGene00047671 21ur-3494 No description available WB:WBGene00047672 21ur-820 Enriched in neurons based on RNA-seq studies. WB:WBGene00047673 21ur-4949 No description available WB:WBGene00047674 21ur-2733 Enriched in neurons based on RNA-seq studies. WB:WBGene00047675 21ur-4764 No description available WB:WBGene00047676 21ur-2539 No description available WB:WBGene00047677 21ur-4887 No description available WB:WBGene00047678 21ur-4017 No description available WB:WBGene00047679 21ur-1468 No description available WB:WBGene00047680 21ur-4370 No description available WB:WBGene00047681 21ur-2210 No description available WB:WBGene00047682 21ur-4465 No description available WB:WBGene00047683 21ur-401 Enriched in neurons based on RNA-seq studies. WB:WBGene00047684 21ur-1565 No description available WB:WBGene00047685 21ur-563 No description available WB:WBGene00047686 21ur-3734 No description available WB:WBGene00047687 21ur-4368 Is affected by eat-2 based on microarray studies. WB:WBGene00047688 21ur-967 No description available WB:WBGene00047689 21ur-5104 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00047690 21ur-3817 No description available WB:WBGene00047691 21ur-1359 No description available WB:WBGene00047692 21ur-2056 No description available WB:WBGene00047693 21ur-2656 No description available WB:WBGene00047694 21ur-12 No description available WB:WBGene00047695 21ur-2855 No description available WB:WBGene00047696 21ur-3109 No description available WB:WBGene00047697 21ur-3827 No description available WB:WBGene00047698 21ur-1467 No description available WB:WBGene00047699 21ur-2569 No description available WB:WBGene00047700 21ur-3138 No description available WB:WBGene00047701 21ur-60 No description available WB:WBGene00047702 21ur-1782 No description available WB:WBGene00047703 21ur-4890 No description available WB:WBGene00047704 21ur-530 No description available WB:WBGene00047705 21ur-4967 No description available WB:WBGene00047706 21ur-2827 No description available WB:WBGene00047707 21ur-3581 No description available WB:WBGene00047708 21ur-2562 Is affected by daf-2 based on microarray studies. WB:WBGene00047709 21ur-1482 No description available WB:WBGene00047710 21ur-4497 Is affected by set-2 based on RNA-seq studies. WB:WBGene00047711 21ur-1211 No description available WB:WBGene00047712 21ur-1328 No description available WB:WBGene00047713 21ur-621 No description available WB:WBGene00047714 21ur-1538 No description available WB:WBGene00047715 21ur-2347 No description available WB:WBGene00047716 21ur-2877 No description available WB:WBGene00047717 21ur-1077 No description available WB:WBGene00047718 21ur-2919 No description available WB:WBGene00047719 21ur-4201 No description available WB:WBGene00047720 21ur-2256 No description available WB:WBGene00047721 21ur-4470 No description available WB:WBGene00047722 21ur-2686 No description available WB:WBGene00047723 21ur-3714 No description available WB:WBGene00047724 21ur-1542 No description available WB:WBGene00047725 21ur-5163 No description available WB:WBGene00047726 21ur-4428 Is affected by xpf-1 based on RNA-seq studies. WB:WBGene00047727 21ur-3861 No description available WB:WBGene00047728 21ur-5136 No description available WB:WBGene00047729 21ur-670 No description available WB:WBGene00047730 21ur-682 No description available WB:WBGene00047731 21ur-4059 No description available WB:WBGene00047732 21ur-4132 No description available WB:WBGene00047733 21ur-5276 No description available WB:WBGene00047734 21ur-4891 No description available WB:WBGene00047735 21ur-1311 No description available WB:WBGene00047736 21ur-2865 No description available WB:WBGene00047737 21ur-2033 No description available WB:WBGene00047738 21ur-2494 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00047739 21ur-3037 No description available WB:WBGene00047740 21ur-5014 No description available WB:WBGene00047741 21ur-4797 No description available WB:WBGene00047742 21ur-330 Enriched in neurons based on RNA-seq studies. WB:WBGene00047743 21ur-1302 No description available WB:WBGene00047744 21ur-829 No description available WB:WBGene00047745 21ur-2280 No description available WB:WBGene00047746 21ur-360 Enriched in neurons based on RNA-seq studies. WB:WBGene00047747 21ur-3540 No description available WB:WBGene00047748 21ur-4298 No description available WB:WBGene00047749 21ur-2440 No description available WB:WBGene00047750 21ur-227 No description available WB:WBGene00047751 21ur-2767 No description available WB:WBGene00047752 21ur-1098 No description available WB:WBGene00047753 21ur-375 No description available WB:WBGene00047754 21ur-2785 No description available WB:WBGene00047755 21ur-4042 Enriched in neurons based on RNA-seq studies. WB:WBGene00047756 21ur-3500 No description available WB:WBGene00047757 21ur-4234 No description available WB:WBGene00047758 21ur-19 No description available WB:WBGene00047759 21ur-3304 No description available WB:WBGene00047760 21ur-2372 No description available WB:WBGene00047761 21ur-2899 No description available WB:WBGene00047762 21ur-4715 No description available WB:WBGene00047763 21ur-5155 Is affected by daf-2 based on microarray studies. WB:WBGene00047764 21ur-975 Is affected by lem-2; emr-1; and rnp-6 based on RNA-seq studies. WB:WBGene00047765 21ur-2775 Enriched in neurons based on RNA-seq studies. WB:WBGene00047766 21ur-3735 No description available WB:WBGene00047767 21ur-5382 No description available WB:WBGene00047768 21ur-5431 No description available WB:WBGene00047769 21ur-656 No description available WB:WBGene00047770 21ur-2697 No description available WB:WBGene00047771 21ur-5294 No description available WB:WBGene00047772 21ur-1275 No description available WB:WBGene00047773 21ur-1748 No description available WB:WBGene00047774 21ur-5366 No description available WB:WBGene00047775 21ur-1731 No description available WB:WBGene00047776 21ur-1251 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00047777 21ur-1833 No description available WB:WBGene00047778 21ur-782 Enriched in neurons based on RNA-seq studies. WB:WBGene00047779 21ur-4737 No description available WB:WBGene00047780 21ur-2022 No description available WB:WBGene00047781 21ur-2346 Enriched in neurons based on RNA-seq studies. WB:WBGene00047782 21ur-2873 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00047783 21ur-5093 No description available WB:WBGene00047784 21ur-4710 Is affected by spt-16 and rnp-6 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies. WB:WBGene00047785 21ur-4607 Is affected by daf-2 based on microarray studies. WB:WBGene00047786 21ur-195 No description available WB:WBGene00047787 21ur-5433 No description available WB:WBGene00047788 21ur-5027 No description available WB:WBGene00047789 21ur-3068 No description available WB:WBGene00047790 21ur-1579 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00047791 21ur-4696 No description available WB:WBGene00047792 21ur-4229 No description available WB:WBGene00047793 21ur-458 No description available WB:WBGene00047794 21ur-1361 No description available WB:WBGene00047795 21ur-3113 No description available WB:WBGene00047796 21ur-4183 No description available WB:WBGene00047797 21ur-3172 No description available WB:WBGene00047798 21ur-366 No description available WB:WBGene00047799 21ur-5447 No description available WB:WBGene00047800 21ur-4901 No description available WB:WBGene00047801 21ur-5000 No description available WB:WBGene00047802 21ur-4631 No description available WB:WBGene00047803 21ur-675 Enriched in neurons based on RNA-seq studies. WB:WBGene00047804 21ur-3995 No description available WB:WBGene00047805 21ur-2599 Is affected by bisphenol A based on RNA-seq studies. WB:WBGene00047806 21ur-1260 No description available WB:WBGene00047807 21ur-638 No description available WB:WBGene00047808 21ur-5315 No description available WB:WBGene00047809 21ur-5036 No description available WB:WBGene00047810 21ur-3187 No description available WB:WBGene00047811 21ur-3145 No description available WB:WBGene00047812 21ur-2713 No description available WB:WBGene00047813 21ur-3613 Is affected by eat-2 based on microarray studies. WB:WBGene00047814 21ur-1320 No description available WB:WBGene00047815 21ur-1752 No description available WB:WBGene00047816 21ur-2612 No description available WB:WBGene00047817 21ur-4537 No description available WB:WBGene00047818 21ur-1963 No description available WB:WBGene00047819 21ur-2447 No description available WB:WBGene00047820 21ur-1101 No description available WB:WBGene00047821 21ur-313 No description available WB:WBGene00047822 21ur-1609 No description available WB:WBGene00047823 21ur-5134 No description available WB:WBGene00047824 21ur-1071 No description available WB:WBGene00047825 21ur-5235 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00047826 21ur-1175 No description available WB:WBGene00047827 21ur-3520 No description available WB:WBGene00047828 21ur-2985 Enriched in neurons based on RNA-seq studies. WB:WBGene00047829 21ur-5264 No description available WB:WBGene00047830 21ur-4173 No description available WB:WBGene00047831 21ur-4787 No description available WB:WBGene00047832 21ur-5268 No description available WB:WBGene00047833 21ur-4343 No description available WB:WBGene00047834 21ur-2878 Enriched in neurons based on RNA-seq studies. WB:WBGene00047835 21ur-199 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00047836 21ur-122 No description available WB:WBGene00047837 21ur-5057 Is affected by rnp-6 and cpl-1 based on RNA-seq studies. WB:WBGene00047838 21ur-3602 No description available WB:WBGene00047839 21ur-3456 No description available WB:WBGene00047840 21ur-1778 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00047841 21ur-5394 No description available WB:WBGene00047842 21ur-343 No description available WB:WBGene00047843 21ur-2912 Enriched in neurons based on RNA-seq studies. WB:WBGene00047844 21ur-4547 No description available WB:WBGene00047845 21ur-5150 No description available WB:WBGene00047846 21ur-5215 No description available WB:WBGene00047847 21ur-1930 No description available WB:WBGene00047848 21ur-3416 No description available WB:WBGene00047849 21ur-2001 No description available WB:WBGene00047850 21ur-2842 No description available WB:WBGene00047851 21ur-4512 No description available WB:WBGene00047852 21ur-2982 No description available WB:WBGene00047853 21ur-1876 No description available WB:WBGene00047854 21ur-4002 Is affected by rnp-6; blmp-1; and cpl-1 based on RNA-seq studies. WB:WBGene00047855 21ur-1117 No description available WB:WBGene00047856 21ur-3398 No description available WB:WBGene00047857 21ur-2816 Enriched in neurons based on RNA-seq studies. Is affected by mett-10 based on RNA-seq studies. WB:WBGene00047858 21ur-3651 No description available WB:WBGene00047859 21ur-2194 No description available WB:WBGene00047860 21ur-2850 Enriched in neurons based on RNA-seq studies. WB:WBGene00047861 21ur-887 No description available WB:WBGene00047862 21ur-2602 No description available WB:WBGene00047863 21ur-1152 No description available WB:WBGene00047864 21ur-202 No description available WB:WBGene00047865 21ur-5169 No description available WB:WBGene00047866 21ur-144 No description available WB:WBGene00047867 21ur-5375 Is affected by lem-2; emr-1; and hmg-3 based on RNA-seq studies. WB:WBGene00047868 21ur-3463 No description available WB:WBGene00047869 21ur-3559 No description available WB:WBGene00047870 21ur-1184 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00047871 21ur-545 No description available WB:WBGene00047872 21ur-4074 No description available WB:WBGene00047873 21ur-2664 No description available WB:WBGene00047874 21ur-2637 No description available WB:WBGene00047875 21ur-3383 No description available WB:WBGene00047876 21ur-562 No description available WB:WBGene00047877 21ur-3970 Enriched in neurons based on RNA-seq studies. WB:WBGene00047878 21ur-3096 No description available WB:WBGene00047879 21ur-742 No description available WB:WBGene00047880 21ur-1162 No description available WB:WBGene00047881 21ur-1390 Enriched in neurons based on RNA-seq studies. WB:WBGene00047882 21ur-4645 No description available WB:WBGene00047883 21ur-3040 No description available WB:WBGene00047884 21ur-834 No description available WB:WBGene00047885 21ur-226 No description available WB:WBGene00047886 21ur-4916 No description available WB:WBGene00047887 21ur-5210 No description available WB:WBGene00047888 21ur-4315 No description available WB:WBGene00047889 21ur-569 No description available WB:WBGene00047890 21ur-482 No description available WB:WBGene00047891 21ur-2114 Enriched in neurons based on RNA-seq studies. WB:WBGene00047892 21ur-2120 No description available WB:WBGene00047893 21ur-134 No description available WB:WBGene00047894 21ur-3152 No description available WB:WBGene00047895 21ur-4094 No description available WB:WBGene00047896 21ur-2891 No description available WB:WBGene00047897 21ur-3532 No description available WB:WBGene00047898 21ur-1515 No description available WB:WBGene00047899 21ur-914 No description available WB:WBGene00047900 21ur-822 No description available WB:WBGene00047901 21ur-5284 Enriched in neurons based on RNA-seq studies. WB:WBGene00047902 21ur-1182 No description available WB:WBGene00047903 21ur-3167 No description available WB:WBGene00047905 21ur-5444 No description available WB:WBGene00047906 21ur-2290 No description available WB:WBGene00047907 21ur-1885 No description available WB:WBGene00047908 21ur-3609 No description available WB:WBGene00047909 21ur-1348 No description available WB:WBGene00047910 21ur-3994 No description available WB:WBGene00047911 21ur-421 No description available WB:WBGene00047912 21ur-4661 No description available WB:WBGene00047913 21ur-3627 No description available WB:WBGene00047914 21ur-3391 No description available WB:WBGene00047915 21ur-1267 No description available WB:WBGene00047916 21ur-2841 No description available WB:WBGene00047917 21ur-3789 Enriched in neurons based on RNA-seq studies. WB:WBGene00047918 21ur-3286 No description available WB:WBGene00047919 21ur-4632 No description available WB:WBGene00047920 21ur-61 No description available WB:WBGene00047921 21ur-873 No description available WB:WBGene00047922 21ur-3020 No description available WB:WBGene00047923 21ur-1658 No description available WB:WBGene00047924 21ur-3552 No description available WB:WBGene00047925 21ur-3292 No description available WB:WBGene00047926 21ur-4942 No description available WB:WBGene00047927 21ur-426 No description available WB:WBGene00047928 21ur-4976 No description available WB:WBGene00047929 21ur-5129 No description available WB:WBGene00047930 21ur-2966 Enriched in neurons based on RNA-seq studies. WB:WBGene00047931 21ur-4498 No description available WB:WBGene00047932 21ur-1032 No description available WB:WBGene00047933 21ur-3321 No description available WB:WBGene00047934 21ur-4481 No description available WB:WBGene00047935 21ur-4840 No description available WB:WBGene00047936 21ur-733 No description available WB:WBGene00047937 21ur-2226 No description available WB:WBGene00047938 21ur-4522 No description available WB:WBGene00047939 21ur-5204 No description available WB:WBGene00047940 21ur-3323 Is affected by meg-3 and meg-4 based on RNA-seq studies. WB:WBGene00047941 21ur-3 No description available WB:WBGene00047942 21ur-1064 No description available WB:WBGene00047943 21ur-4208 No description available WB:WBGene00047944 21ur-2471 No description available WB:WBGene00047945 21ur-1449 No description available WB:WBGene00047946 21ur-3934 No description available WB:WBGene00047947 21ur-5195 No description available WB:WBGene00047948 21ur-3298 No description available WB:WBGene00047949 21ur-2260 No description available WB:WBGene00047950 21ur-497 No description available WB:WBGene00047951 21ur-940 No description available WB:WBGene00047952 21ur-1957 No description available WB:WBGene00047953 21ur-3087 No description available WB:WBGene00047954 21ur-2231 No description available WB:WBGene00047955 21ur-291 No description available WB:WBGene00047956 21ur-238 No description available WB:WBGene00047957 21ur-4816 No description available WB:WBGene00047958 21ur-5301 No description available WB:WBGene00047959 21ur-3539 No description available WB:WBGene00047960 21ur-2061 No description available WB:WBGene00047961 21ur-524 No description available WB:WBGene00047962 21ur-1537 No description available WB:WBGene00047963 21ur-3703 No description available WB:WBGene00047964 21ur-4297 No description available WB:WBGene00047965 21ur-1080 No description available WB:WBGene00047966 21ur-3188 No description available WB:WBGene00047967 21ur-4734 No description available WB:WBGene00047968 21ur-4586 No description available WB:WBGene00047969 21ur-1942 No description available WB:WBGene00047970 21ur-5205 No description available WB:WBGene00047971 21ur-4451 No description available WB:WBGene00047972 21ur-2294 No description available WB:WBGene00047973 21ur-1962 No description available WB:WBGene00047974 21ur-304 No description available WB:WBGene00047975 21ur-5050 No description available WB:WBGene00047976 21ur-1683 Enriched in neurons based on RNA-seq studies. WB:WBGene00047977 21ur-2700 No description available WB:WBGene00047978 21ur-2238 No description available WB:WBGene00047979 21ur-3331 No description available WB:WBGene00047980 21ur-4847 No description available WB:WBGene00047981 21ur-1445 No description available WB:WBGene00047982 21ur-4122 No description available WB:WBGene00047983 21ur-3029 No description available WB:WBGene00047984 21ur-1159 No description available WB:WBGene00047985 21ur-4446 No description available WB:WBGene00047986 21ur-2067 No description available WB:WBGene00047987 21ur-1010 No description available WB:WBGene00047988 21ur-2174 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00047989 21ur-32 No description available WB:WBGene00047990 21ur-4080 No description available WB:WBGene00047991 21ur-3899 No description available WB:WBGene00047992 21ur-559 No description available WB:WBGene00047993 21ur-3014 No description available WB:WBGene00047994 21ur-5240 No description available WB:WBGene00047995 21ur-2558 No description available WB:WBGene00047996 21ur-4301 No description available WB:WBGene00047997 21ur-1800 No description available WB:WBGene00047998 21ur-3885 No description available WB:WBGene00047999 21ur-1427 No description available WB:WBGene00048000 21ur-4854 No description available WB:WBGene00048001 21ur-2199 No description available WB:WBGene00048002 21ur-5183 No description available WB:WBGene00048003 21ur-3655 No description available WB:WBGene00048004 21ur-392 No description available WB:WBGene00048005 21ur-2838 No description available WB:WBGene00048006 21ur-2690 No description available WB:WBGene00048007 21ur-4613 No description available WB:WBGene00048008 21ur-3231 No description available WB:WBGene00048009 21ur-1218 No description available WB:WBGene00048010 21ur-2671 Is affected by set-2 based on RNA-seq studies. WB:WBGene00048011 21ur-2716 No description available WB:WBGene00048012 21ur-1777 No description available WB:WBGene00048013 21ur-3598 No description available WB:WBGene00048014 21ur-4996 No description available WB:WBGene00048015 21ur-609 No description available WB:WBGene00048016 21ur-2796 No description available WB:WBGene00048017 21ur-3361 No description available WB:WBGene00048018 21ur-3663 No description available WB:WBGene00048019 21ur-5043 No description available WB:WBGene00048020 21ur-3954 No description available WB:WBGene00048021 21ur-510 No description available WB:WBGene00048022 21ur-1811 No description available WB:WBGene00048023 21ur-1611 No description available WB:WBGene00048024 21ur-845 No description available WB:WBGene00048025 21ur-4155 No description available WB:WBGene00048026 21ur-3845 No description available WB:WBGene00048027 21ur-2147 No description available WB:WBGene00048028 21ur-1807 No description available WB:WBGene00048029 21ur-5022 No description available WB:WBGene00048030 21ur-4609 No description available WB:WBGene00048031 21ur-851 No description available WB:WBGene00048032 21ur-4039 No description available WB:WBGene00048033 21ur-2425 No description available WB:WBGene00048034 21ur-3419 No description available WB:WBGene00048035 21ur-2079 No description available WB:WBGene00048036 21ur-1108 No description available WB:WBGene00048037 21ur-5438 Enriched in neurons based on RNA-seq studies. WB:WBGene00048038 21ur-3774 No description available WB:WBGene00048039 21ur-3905 No description available WB:WBGene00048040 21ur-77 No description available WB:WBGene00048041 21ur-418 No description available WB:WBGene00048042 21ur-145 No description available WB:WBGene00048043 21ur-4803 No description available WB:WBGene00048044 21ur-2771 No description available WB:WBGene00048045 21ur-356 No description available WB:WBGene00048046 21ur-3904 No description available WB:WBGene00048047 21ur-4308 No description available WB:WBGene00048048 21ur-519 No description available WB:WBGene00048049 21ur-724 No description available WB:WBGene00048050 21ur-4083 No description available WB:WBGene00048051 21ur-4716 Enriched in neurons based on RNA-seq studies. WB:WBGene00048052 21ur-1675 Enriched in neurons based on RNA-seq studies. WB:WBGene00048053 21ur-470 No description available WB:WBGene00048054 21ur-4276 Enriched in neurons based on RNA-seq studies. WB:WBGene00048055 21ur-4382 No description available WB:WBGene00048056 21ur-3374 No description available WB:WBGene00048057 21ur-1189 No description available WB:WBGene00048058 21ur-3763 No description available WB:WBGene00048059 21ur-4103 No description available WB:WBGene00048060 21ur-1838 No description available WB:WBGene00048061 21ur-4873 No description available WB:WBGene00048062 21ur-2670 No description available WB:WBGene00048063 21ur-2247 No description available WB:WBGene00048064 21ur-2646 No description available WB:WBGene00048065 21ur-576 No description available WB:WBGene00048066 21ur-4220 No description available WB:WBGene00048067 21ur-817 No description available WB:WBGene00048068 21ur-1834 Enriched in neurons based on RNA-seq studies. WB:WBGene00048069 21ur-1724 No description available WB:WBGene00048070 21ur-2368 No description available WB:WBGene00048071 21ur-3303 No description available WB:WBGene00048072 21ur-3274 No description available WB:WBGene00048073 21ur-2100 No description available WB:WBGene00048074 21ur-5239 No description available WB:WBGene00048075 21ur-4552 No description available WB:WBGene00048076 21ur-577 No description available WB:WBGene00048077 21ur-1645 No description available WB:WBGene00048078 21ur-3312 No description available WB:WBGene00048079 21ur-2979 No description available WB:WBGene00048080 21ur-1646 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00048081 21ur-4029 No description available WB:WBGene00048082 21ur-4100 No description available WB:WBGene00048083 21ur-5308 Enriched in neurons based on RNA-seq studies. WB:WBGene00048084 21ur-708 No description available WB:WBGene00048085 21ur-2331 No description available WB:WBGene00048086 21ur-604 No description available WB:WBGene00048087 21ur-618 No description available WB:WBGene00048088 21ur-5348 No description available WB:WBGene00048089 21ur-945 No description available WB:WBGene00048090 21ur-2200 Enriched in sensory neurons based on RNA-seq studies. Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00048091 21ur-543 No description available WB:WBGene00048092 21ur-1398 No description available WB:WBGene00048093 21ur-1335 No description available WB:WBGene00048094 21ur-1091 Is affected by set-2 based on RNA-seq studies. WB:WBGene00048095 21ur-1783 No description available WB:WBGene00048096 21ur-2006 No description available WB:WBGene00048097 21ur-1385 No description available WB:WBGene00048098 21ur-644 No description available WB:WBGene00048099 21ur-1974 No description available WB:WBGene00048100 21ur-4162 No description available WB:WBGene00048101 21ur-2301 No description available WB:WBGene00048102 21ur-4393 No description available WB:WBGene00048103 21ur-3495 No description available WB:WBGene00048104 21ur-4875 No description available WB:WBGene00048105 21ur-1330 No description available WB:WBGene00048106 21ur-3226 No description available WB:WBGene00048107 21ur-3139 No description available WB:WBGene00048108 21ur-4988 No description available WB:WBGene00048109 21ur-2480 No description available WB:WBGene00048110 21ur-3243 No description available WB:WBGene00048111 21ur-3448 No description available WB:WBGene00048112 21ur-4621 Enriched in neurons based on RNA-seq studies. WB:WBGene00048113 21ur-866 No description available WB:WBGene00048114 21ur-4119 No description available WB:WBGene00048115 21ur-3869 No description available WB:WBGene00048116 21ur-2862 No description available WB:WBGene00048117 21ur-636 No description available WB:WBGene00048118 21ur-1178 No description available WB:WBGene00048119 21ur-4674 No description available WB:WBGene00048120 21ur-3210 No description available WB:WBGene00048121 21ur-3923 No description available WB:WBGene00048122 21ur-1254 No description available WB:WBGene00048123 21ur-388 No description available WB:WBGene00048124 21ur-4980 No description available WB:WBGene00048125 21ur-4515 No description available WB:WBGene00048126 21ur-3470 No description available WB:WBGene00048127 21ur-1543 No description available WB:WBGene00048128 21ur-4729 No description available WB:WBGene00048129 21ur-3719 Enriched in neurons based on RNA-seq studies. WB:WBGene00048130 21ur-3671 No description available WB:WBGene00048131 21ur-489 No description available WB:WBGene00048132 21ur-1421 No description available WB:WBGene00048133 21ur-3252 No description available WB:WBGene00048134 21ur-911 No description available WB:WBGene00048135 21ur-3159 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00048136 21ur-2452 No description available WB:WBGene00048137 21ur-3782 No description available WB:WBGene00048138 21ur-2813 No description available WB:WBGene00048139 21ur-5191 No description available WB:WBGene00048140 21ur-1357 No description available WB:WBGene00048141 21ur-5009 No description available WB:WBGene00048142 21ur-2808 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00048143 21ur-3721 No description available WB:WBGene00048144 21ur-3247 No description available WB:WBGene00048145 21ur-1410 No description available WB:WBGene00048146 21ur-3205 No description available WB:WBGene00048147 21ur-184 No description available WB:WBGene00048148 21ur-935 No description available WB:WBGene00048149 21ur-2593 No description available WB:WBGene00048150 21ur-1419 No description available WB:WBGene00048151 21ur-3568 No description available WB:WBGene00048152 21ur-4652 No description available WB:WBGene00048153 21ur-3355 No description available WB:WBGene00048154 21ur-1634 No description available WB:WBGene00048155 21ur-3645 No description available WB:WBGene00048156 21ur-846 No description available WB:WBGene00048157 21ur-1796 No description available WB:WBGene00048158 21ur-2536 No description available WB:WBGene00048159 21ur-3427 No description available WB:WBGene00048160 21ur-2450 No description available WB:WBGene00048161 21ur-1298 No description available WB:WBGene00048162 21ur-3560 No description available WB:WBGene00048163 21ur-4131 No description available WB:WBGene00048164 21ur-2327 No description available WB:WBGene00048165 21ur-4283 No description available WB:WBGene00048166 21ur-96 No description available WB:WBGene00048167 21ur-2839 No description available WB:WBGene00048168 21ur-4064 No description available WB:WBGene00048169 21ur-2021 No description available WB:WBGene00048170 21ur-1207 Enriched in neurons based on RNA-seq studies. Is affected by hpl-2 and lpd-3 based on RNA-seq studies. WB:WBGene00048171 21ur-285 No description available WB:WBGene00048172 21ur-930 No description available WB:WBGene00048173 21ur-161 No description available WB:WBGene00048174 21ur-5188 No description available WB:WBGene00048175 21ur-3367 No description available WB:WBGene00048176 21ur-3377 No description available WB:WBGene00048177 21ur-1009 No description available WB:WBGene00048178 21ur-549 No description available WB:WBGene00048179 21ur-749 No description available WB:WBGene00048180 21ur-890 No description available WB:WBGene00048181 21ur-3594 No description available WB:WBGene00048182 21ur-2488 No description available WB:WBGene00048183 21ur-3123 No description available WB:WBGene00048184 21ur-4912 No description available WB:WBGene00048185 21ur-2248 No description available WB:WBGene00048186 21ur-208 Enriched in neurons based on RNA-seq studies. WB:WBGene00048187 21ur-4659 No description available WB:WBGene00048188 21ur-1442 No description available WB:WBGene00048189 21ur-4170 No description available WB:WBGene00048190 21ur-4977 No description available WB:WBGene00048191 21ur-2483 No description available WB:WBGene00048192 21ur-5189 No description available WB:WBGene00048193 21ur-3679 No description available WB:WBGene00048194 21ur-3211 No description available WB:WBGene00048195 21ur-484 Enriched in neurons based on RNA-seq studies. WB:WBGene00048196 21ur-1832 No description available WB:WBGene00048197 21ur-4433 No description available WB:WBGene00048198 21ur-5350 No description available WB:WBGene00048199 21ur-2949 No description available WB:WBGene00048200 21ur-1972 No description available WB:WBGene00048201 21ur-2045 No description available WB:WBGene00048202 21ur-3975 No description available WB:WBGene00048203 21ur-934 No description available WB:WBGene00048204 21ur-2652 No description available WB:WBGene00048205 21ur-2322 No description available WB:WBGene00048206 21ur-138 No description available WB:WBGene00048207 21ur-3295 No description available WB:WBGene00048208 21ur-2896 No description available WB:WBGene00048209 21ur-1063 No description available WB:WBGene00048210 21ur-4776 No description available WB:WBGene00048211 21ur-4240 No description available WB:WBGene00048212 21ur-4878 No description available WB:WBGene00048213 21ur-1129 No description available WB:WBGene00048214 21ur-2165 No description available WB:WBGene00048215 21ur-4018 No description available WB:WBGene00048216 21ur-2257 No description available WB:WBGene00048217 21ur-989 No description available WB:WBGene00048218 21ur-4369 No description available WB:WBGene00048219 21ur-4305 No description available WB:WBGene00048220 21ur-3687 No description available WB:WBGene00048221 21ur-501 No description available WB:WBGene00048222 21ur-1667 No description available WB:WBGene00048223 21ur-4225 No description available WB:WBGene00048224 21ur-4720 No description available WB:WBGene00048225 21ur-4628 No description available WB:WBGene00048226 21ur-2764 No description available WB:WBGene00048227 21ur-2815 No description available WB:WBGene00048228 21ur-1050 No description available WB:WBGene00048229 21ur-1391 No description available WB:WBGene00048230 21ur-1596 No description available WB:WBGene00048231 21ur-4019 No description available WB:WBGene00048232 21ur-637 No description available WB:WBGene00048233 21ur-4933 No description available WB:WBGene00048234 21ur-684 Is affected by hpl-2 and mrps-5 based on RNA-seq studies. WB:WBGene00048235 21ur-918 No description available WB:WBGene00048236 21ur-4460 No description available WB:WBGene00048237 21ur-1473 No description available WB:WBGene00048238 21ur-5327 Is affected by several genes including set-2; lem-2; and emr-1 based on RNA-seq studies. WB:WBGene00048239 21ur-1931 No description available WB:WBGene00048240 21ur-1711 No description available WB:WBGene00048241 21ur-5 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00048242 21ur-5061 No description available WB:WBGene00048243 21ur-3358 No description available WB:WBGene00048244 21ur-2229 No description available WB:WBGene00048245 21ur-574 No description available WB:WBGene00048246 21ur-389 No description available WB:WBGene00048247 21ur-288 No description available WB:WBGene00048248 21ur-183 No description available WB:WBGene00048249 21ur-253 No description available WB:WBGene00048250 21ur-1858 No description available WB:WBGene00048251 21ur-4836 No description available WB:WBGene00048252 21ur-2990 No description available WB:WBGene00048253 21ur-4001 No description available WB:WBGene00048254 21ur-276 No description available WB:WBGene00048255 21ur-1642 No description available WB:WBGene00048256 21ur-1194 No description available WB:WBGene00048257 21ur-4753 No description available WB:WBGene00048258 21ur-800 No description available WB:WBGene00048259 21ur-2798 No description available WB:WBGene00048260 21ur-3443 Is affected by set-2 based on RNA-seq studies. WB:WBGene00048261 21ur-1553 No description available WB:WBGene00048262 21ur-1926 No description available WB:WBGene00048263 21ur-566 No description available WB:WBGene00048264 21ur-3561 No description available WB:WBGene00048265 21ur-4210 No description available WB:WBGene00048266 21ur-3270 No description available WB:WBGene00048267 21ur-3387 No description available WB:WBGene00048268 21ur-977 No description available WB:WBGene00048269 21ur-475 No description available WB:WBGene00048270 21ur-2821 No description available WB:WBGene00048271 21ur-3090 No description available WB:WBGene00048272 21ur-4362 No description available WB:WBGene00048273 21ur-2629 Is affected by eat-2 based on microarray studies. WB:WBGene00048274 21ur-1789 No description available WB:WBGene00048275 21ur-464 No description available WB:WBGene00048276 21ur-2341 No description available WB:WBGene00048277 21ur-4745 No description available WB:WBGene00048278 21ur-4022 No description available WB:WBGene00048279 21ur-4424 No description available WB:WBGene00048280 21ur-3036 No description available WB:WBGene00048281 21ur-4742 No description available WB:WBGene00048282 21ur-5243 No description available WB:WBGene00048283 21ur-1517 No description available WB:WBGene00048284 21ur-2866 No description available WB:WBGene00048285 21ur-1017 No description available WB:WBGene00048286 21ur-3707 Enriched in neurons based on RNA-seq studies. WB:WBGene00048287 21ur-848 No description available WB:WBGene00048288 21ur-1087 No description available WB:WBGene00048289 21ur-5148 No description available WB:WBGene00048290 21ur-1107 No description available WB:WBGene00048291 21ur-941 No description available WB:WBGene00048292 21ur-3132 No description available WB:WBGene00048293 21ur-4286 No description available WB:WBGene00048294 21ur-3181 No description available WB:WBGene00048295 21ur-4197 No description available WB:WBGene00048296 21ur-2438 No description available WB:WBGene00048297 21ur-5296 No description available WB:WBGene00048298 21ur-3743 No description available WB:WBGene00048299 21ur-2429 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00048300 21ur-4639 No description available WB:WBGene00048301 21ur-1869 No description available WB:WBGene00048302 21ur-3241 No description available WB:WBGene00048303 21ur-4502 No description available WB:WBGene00048304 21ur-1661 No description available WB:WBGene00048305 21ur-1655 No description available WB:WBGene00048306 21ur-2900 Enriched in neurons based on RNA-seq studies. WB:WBGene00048307 21ur-1945 No description available WB:WBGene00048308 21ur-3988 No description available WB:WBGene00048309 21ur-1660 No description available WB:WBGene00048310 21ur-4081 No description available WB:WBGene00048311 21ur-2776 No description available WB:WBGene00048312 21ur-1255 No description available WB:WBGene00048313 21ur-3301 No description available WB:WBGene00048314 21ur-5333 No description available WB:WBGene00048315 21ur-1332 No description available WB:WBGene00048316 21ur-830 No description available WB:WBGene00048317 21ur-4051 No description available WB:WBGene00048318 21ur-2289 No description available WB:WBGene00048319 21ur-3364 No description available WB:WBGene00048320 21ur-2749 No description available WB:WBGene00048321 21ur-4808 No description available WB:WBGene00048322 21ur-1784 No description available WB:WBGene00048323 21ur-2805 Is affected by Ketamine based on RNA-seq studies. WB:WBGene00048324 21ur-1338 No description available WB:WBGene00048325 21ur-3662 No description available WB:WBGene00048326 21ur-3485 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00048327 21ur-3044 No description available WB:WBGene00048328 21ur-1678 Enriched in neurons based on RNA-seq studies. WB:WBGene00048329 21ur-5012 No description available WB:WBGene00048330 21ur-4102 No description available WB:WBGene00048331 21ur-2003 No description available WB:WBGene00048332 21ur-3086 No description available WB:WBGene00048333 21ur-2302 No description available WB:WBGene00048334 21ur-1150 Enriched in neurons based on RNA-seq studies. WB:WBGene00048335 21ur-2202 No description available WB:WBGene00048336 21ur-540 No description available WB:WBGene00048337 21ur-852 No description available WB:WBGene00048338 21ur-2359 Enriched in neurons based on RNA-seq studies. WB:WBGene00048339 21ur-3742 No description available WB:WBGene00048340 21ur-44 No description available WB:WBGene00048341 21ur-1138 No description available WB:WBGene00048342 21ur-635 No description available WB:WBGene00048343 21ur-1958 No description available WB:WBGene00048344 21ur-3785 No description available WB:WBGene00048345 21ur-1191 No description available WB:WBGene00048346 21ur-2737 No description available WB:WBGene00048347 21ur-3908 No description available WB:WBGene00048348 21ur-1950 No description available WB:WBGene00048349 21ur-296 No description available WB:WBGene00048350 21ur-4179 Enriched in neurons based on RNA-seq studies. WB:WBGene00048351 21ur-2498 No description available WB:WBGene00048352 21ur-309 No description available WB:WBGene00048353 21ur-2676 No description available WB:WBGene00048354 21ur-2218 No description available WB:WBGene00048355 21ur-2152 Enriched in neurons based on RNA-seq studies. WB:WBGene00048356 21ur-3875 No description available WB:WBGene00048357 21ur-4853 No description available WB:WBGene00048358 21ur-3227 No description available WB:WBGene00048359 21ur-4378 No description available WB:WBGene00048360 21ur-3230 No description available WB:WBGene00048361 21ur-3880 No description available WB:WBGene00048362 21ur-5388 No description available WB:WBGene00048363 21ur-3324 No description available WB:WBGene00048364 21ur-723 No description available WB:WBGene00048365 21ur-1801 No description available WB:WBGene00048366 21ur-1699 No description available WB:WBGene00048367 21ur-1161 No description available WB:WBGene00048368 21ur-4872 No description available WB:WBGene00048369 21ur-1638 No description available WB:WBGene00048370 21ur-861 No description available WB:WBGene00048371 21ur-1100 No description available WB:WBGene00048372 21ur-1186 No description available WB:WBGene00048373 21ur-2833 No description available WB:WBGene00048374 21ur-2666 No description available WB:WBGene00048375 21ur-27 No description available WB:WBGene00048376 21ur-1991 No description available WB:WBGene00048377 21ur-2121 No description available WB:WBGene00048378 21ur-4535 No description available WB:WBGene00048379 21ur-872 No description available WB:WBGene00048380 21ur-600 No description available WB:WBGene00048381 21ur-5203 No description available WB:WBGene00048382 21ur-694 Enriched in neurons based on RNA-seq studies. WB:WBGene00048383 21ur-1424 No description available WB:WBGene00048384 21ur-3015 No description available WB:WBGene00048385 21ur-1437 No description available WB:WBGene00048386 21ur-1595 No description available WB:WBGene00048387 21ur-738 No description available WB:WBGene00048388 21ur-1877 No description available WB:WBGene00048389 21ur-94 No description available WB:WBGene00048390 21ur-3753 No description available WB:WBGene00048391 21ur-5399 No description available WB:WBGene00048392 21ur-996 No description available WB:WBGene00048393 21ur-3879 No description available WB:WBGene00048394 21ur-302 No description available WB:WBGene00048395 21ur-3702 No description available WB:WBGene00048396 21ur-3201 No description available WB:WBGene00048397 21ur-4321 No description available WB:WBGene00048398 21ur-4484 No description available WB:WBGene00048399 21ur-4071 No description available WB:WBGene00048400 21ur-2388 No description available WB:WBGene00048401 21ur-5186 No description available WB:WBGene00048402 21ur-207 Is affected by set-2 based on RNA-seq studies. WB:WBGene00048403 21ur-4990 No description available WB:WBGene00048404 21ur-660 No description available WB:WBGene00048405 21ur-1939 No description available WB:WBGene00048406 21ur-4760 No description available WB:WBGene00048407 21ur-4948 No description available WB:WBGene00048408 21ur-318 No description available WB:WBGene00048409 21ur-5058 No description available WB:WBGene00048410 21ur-5289 No description available WB:WBGene00048411 21ur-3105 No description available WB:WBGene00048412 21ur-811 No description available WB:WBGene00048413 21ur-3678 No description available WB:WBGene00048414 21ur-2057 No description available WB:WBGene00048415 21ur-2128 No description available WB:WBGene00048416 21ur-1714 No description available WB:WBGene00048417 21ur-4657 No description available WB:WBGene00048418 21ur-3521 No description available WB:WBGene00048419 21ur-171 No description available WB:WBGene00048420 21ur-2742 No description available WB:WBGene00048421 21ur-1998 No description available WB:WBGene00048422 21ur-3574 No description available WB:WBGene00048423 21ur-939 No description available WB:WBGene00048424 21ur-3154 No description available WB:WBGene00048425 21ur-4095 No description available WB:WBGene00048426 21ur-4735 No description available WB:WBGene00048427 21ur-99 No description available WB:WBGene00048428 21ur-3275 No description available WB:WBGene00048429 21ur-4908 Enriched in neurons based on RNA-seq studies. WB:WBGene00048430 21ur-1656 No description available WB:WBGene00048431 21ur-4371 No description available WB:WBGene00048432 21ur-4207 No description available WB:WBGene00048433 21ur-1380 No description available WB:WBGene00048434 21ur-716 No description available WB:WBGene00048435 21ur-3965 No description available WB:WBGene00048436 21ur-1232 No description available WB:WBGene00048437 21ur-142 No description available WB:WBGene00048438 21ur-4496 No description available WB:WBGene00048439 21ur-89 No description available WB:WBGene00048440 21ur-2334 No description available WB:WBGene00048441 21ur-3380 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00048442 21ur-3826 No description available WB:WBGene00048443 21ur-3468 No description available WB:WBGene00048444 21ur-218 No description available WB:WBGene00048445 21ur-915 Enriched in neurons based on RNA-seq studies. WB:WBGene00048446 21ur-2405 No description available WB:WBGene00048447 21ur-8 No description available WB:WBGene00048448 21ur-1239 No description available WB:WBGene00048449 21ur-4678 No description available WB:WBGene00048450 21ur-3250 No description available WB:WBGene00048451 21ur-4919 No description available WB:WBGene00048452 21ur-244 No description available WB:WBGene00048453 21ur-3892 No description available WB:WBGene00048454 21ur-3370 No description available WB:WBGene00048455 21ur-454 No description available WB:WBGene00048456 21ur-1349 No description available WB:WBGene00048457 21ur-1406 Enriched in neurons based on RNA-seq studies. WB:WBGene00048458 21ur-5418 No description available WB:WBGene00048459 21ur-4842 No description available WB:WBGene00048460 21ur-1168 Enriched in neurons based on RNA-seq studies. WB:WBGene00048461 21ur-1625 No description available WB:WBGene00048462 21ur-4827 Enriched in neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00048463 21ur-5238 No description available WB:WBGene00048464 21ur-3865 No description available WB:WBGene00048465 21ur-2608 No description available WB:WBGene00048466 21ur-2050 No description available WB:WBGene00048467 21ur-5020 Enriched in neurons based on RNA-seq studies. WB:WBGene00048468 21ur-5220 No description available WB:WBGene00048469 21ur-2115 No description available WB:WBGene00048470 21ur-3501 Enriched in neurons based on RNA-seq studies. WB:WBGene00048471 21ur-3023 No description available WB:WBGene00048472 21ur-5164 No description available WB:WBGene00048473 21ur-261 No description available WB:WBGene00048474 21ur-1816 No description available WB:WBGene00048475 21ur-2233 No description available WB:WBGene00048476 21ur-4070 No description available WB:WBGene00048477 21ur-2028 No description available WB:WBGene00048478 21ur-117 No description available WB:WBGene00048479 21ur-2606 No description available WB:WBGene00048480 21ur-2224 No description available WB:WBGene00048481 21ur-3028 No description available WB:WBGene00048482 21ur-1737 No description available WB:WBGene00048483 21ur-4320 No description available WB:WBGene00048484 21ur-1541 No description available WB:WBGene00048485 21ur-4077 No description available WB:WBGene00048486 21ur-2235 No description available WB:WBGene00048487 21ur-1371 No description available WB:WBGene00048488 21ur-3392 No description available WB:WBGene00048489 21ur-106 No description available WB:WBGene00048490 21ur-4595 No description available WB:WBGene00048491 21ur-1631 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00048492 21ur-2553 No description available WB:WBGene00048493 21ur-828 No description available WB:WBGene00048494 21ur-2106 No description available WB:WBGene00048495 21ur-131 No description available WB:WBGene00048496 21ur-2683 No description available WB:WBGene00048497 21ur-5307 No description available WB:WBGene00048498 21ur-2618 No description available WB:WBGene00048499 21ur-790 No description available WB:WBGene00048500 21ur-2965 No description available WB:WBGene00048501 21ur-290 No description available WB:WBGene00048502 21ur-5316 No description available WB:WBGene00048503 21ur-865 No description available WB:WBGene00048504 21ur-3956 No description available WB:WBGene00048505 21ur-2633 No description available WB:WBGene00048506 21ur-3558 No description available WB:WBGene00048507 21ur-3039 No description available WB:WBGene00048508 21ur-414 No description available WB:WBGene00048509 21ur-4910 No description available WB:WBGene00048510 21ur-976 No description available WB:WBGene00048511 21ur-3888 No description available WB:WBGene00048512 21ur-955 Enriched in neurons based on RNA-seq studies. WB:WBGene00048513 21ur-2458 No description available WB:WBGene00048514 21ur-3716 No description available WB:WBGene00048515 21ur-2311 No description available WB:WBGene00048516 21ur-2326 No description available WB:WBGene00048517 21ur-3807 No description available WB:WBGene00048518 21ur-1221 No description available WB:WBGene00048519 21ur-1632 No description available WB:WBGene00048520 21ur-2692 No description available WB:WBGene00048521 21ur-538 No description available WB:WBGene00048522 21ur-1157 No description available WB:WBGene00048523 21ur-4641 No description available WB:WBGene00048524 21ur-4037 No description available WB:WBGene00048525 21ur-2851 No description available WB:WBGene00048526 21ur-4863 No description available WB:WBGene00048527 21ur-4146 No description available WB:WBGene00048528 21ur-2527 No description available WB:WBGene00048529 21ur-5286 No description available WB:WBGene00048530 21ur-3488 No description available WB:WBGene00048531 21ur-3085 No description available WB:WBGene00048532 21ur-3038 No description available WB:WBGene00048533 21ur-3050 No description available WB:WBGene00048534 21ur-5340 No description available WB:WBGene00048535 21ur-1606 No description available WB:WBGene00048536 21ur-2038 No description available WB:WBGene00048537 21ur-667 No description available WB:WBGene00048538 21ur-1133 No description available WB:WBGene00048539 21ur-2880 No description available WB:WBGene00048540 21ur-2978 No description available WB:WBGene00048541 21ur-3417 No description available WB:WBGene00048542 21ur-4332 No description available WB:WBGene00048543 21ur-4495 No description available WB:WBGene00048544 21ur-923 No description available WB:WBGene00048545 21ur-3266 No description available WB:WBGene00048546 21ur-45 No description available WB:WBGene00048547 21ur-4198 No description available WB:WBGene00048548 21ur-3302 Enriched in neurons based on RNA-seq studies. WB:WBGene00048549 21ur-4514 No description available WB:WBGene00048550 21ur-3925 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00048551 21ur-2983 No description available WB:WBGene00048552 21ur-4817 No description available WB:WBGene00048553 21ur-1321 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00048554 21ur-2072 No description available WB:WBGene00048555 21ur-613 No description available WB:WBGene00048556 21ur-1981 No description available WB:WBGene00048557 21ur-5069 No description available WB:WBGene00048558 21ur-3614 No description available WB:WBGene00048559 21ur-786 No description available WB:WBGene00048560 21ur-5035 No description available WB:WBGene00048561 21ur-2157 No description available WB:WBGene00048562 21ur-4217 No description available WB:WBGene00048563 21ur-1081 No description available WB:WBGene00048564 21ur-2799 No description available WB:WBGene00048565 21ur-3471 No description available WB:WBGene00048566 21ur-3694 No description available WB:WBGene00048567 21ur-3776 No description available WB:WBGene00048568 21ur-2472 No description available WB:WBGene00048569 21ur-4113 No description available WB:WBGene00048570 21ur-1705 No description available WB:WBGene00048571 21ur-1849 No description available WB:WBGene00048572 21ur-4677 No description available WB:WBGene00048573 21ur-4587 No description available WB:WBGene00048574 21ur-5090 No description available WB:WBGene00048575 21ur-2330 No description available WB:WBGene00048576 21ur-5096 No description available WB:WBGene00048577 21ur-3426 No description available WB:WBGene00048578 21ur-2560 No description available WB:WBGene00048579 21ur-624 No description available WB:WBGene00048580 21ur-1202 No description available WB:WBGene00048581 21ur-4958 No description available WB:WBGene00048582 21ur-2549 No description available WB:WBGene00048583 21ur-4239 Enriched in neurons based on RNA-seq studies. WB:WBGene00048584 21ur-5161 No description available WB:WBGene00048585 21ur-4130 No description available WB:WBGene00048586 21ur-4882 No description available WB:WBGene00048587 21ur-3511 No description available WB:WBGene00048588 21ur-4867 No description available WB:WBGene00048589 21ur-672 No description available WB:WBGene00048590 21ur-1045 No description available WB:WBGene00048591 21ur-3575 No description available WB:WBGene00048592 21ur-1569 No description available WB:WBGene00048593 21ur-4780 No description available WB:WBGene00048594 21ur-1174 No description available WB:WBGene00048595 21ur-2349 No description available WB:WBGene00048596 21ur-2519 No description available WB:WBGene00048597 21ur-3722 No description available WB:WBGene00048598 21ur-589 No description available WB:WBGene00048599 21ur-2543 No description available WB:WBGene00048600 21ur-3794 No description available WB:WBGene00048601 21ur-3064 No description available WB:WBGene00048602 21ur-1122 No description available WB:WBGene00048603 21ur-2275 No description available WB:WBGene00048604 21ur-1297 No description available WB:WBGene00048605 21ur-2931 No description available WB:WBGene00048606 21ur-1358 No description available WB:WBGene00048607 21ur-3955 No description available WB:WBGene00048608 21ur-2885 No description available WB:WBGene00048609 21ur-709 No description available WB:WBGene00048610 21ur-3151 No description available WB:WBGene00048611 21ur-1760 Enriched in neurons based on RNA-seq studies. WB:WBGene00048612 21ur-2484 No description available WB:WBGene00048613 21ur-2907 No description available WB:WBGene00048614 21ur-3147 No description available WB:WBGene00048615 21ur-3401 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00048616 21ur-2894 No description available WB:WBGene00048617 21ur-3909 No description available WB:WBGene00048618 21ur-364 No description available WB:WBGene00048619 21ur-2782 No description available WB:WBGene00048620 21ur-3814 No description available WB:WBGene00048621 21ur-4534 No description available WB:WBGene00048622 21ur-151 No description available WB:WBGene00048623 21ur-3518 No description available WB:WBGene00048624 21ur-1056 No description available WB:WBGene00048625 21ur-3667 No description available WB:WBGene00048626 21ur-3140 No description available WB:WBGene00048627 21ur-4232 Is affected by daf-2 based on microarray studies. WB:WBGene00048628 21ur-760 No description available WB:WBGene00048629 21ur-599 No description available WB:WBGene00048630 21ur-4960 No description available WB:WBGene00048631 21ur-1307 No description available WB:WBGene00048632 21ur-5081 Enriched in neurons based on RNA-seq studies. WB:WBGene00048633 21ur-4200 No description available WB:WBGene00048634 21ur-4084 No description available WB:WBGene00048635 21ur-2462 No description available WB:WBGene00048636 21ur-4560 No description available WB:WBGene00048637 21ur-2184 No description available WB:WBGene00048638 21ur-3111 No description available WB:WBGene00048639 21ur-523 No description available WB:WBGene00048640 21ur-3059 No description available WB:WBGene00048641 21ur-774 No description available WB:WBGene00048642 21ur-5398 No description available WB:WBGene00048643 21ur-1610 No description available WB:WBGene00048644 21ur-1020 No description available WB:WBGene00048645 21ur-4648 No description available WB:WBGene00048646 21ur-4819 Enriched in neurons based on RNA-seq studies. WB:WBGene00048647 21ur-2151 No description available WB:WBGene00048648 21ur-4139 No description available WB:WBGene00048649 21ur-2950 No description available WB:WBGene00048650 21ur-3982 No description available WB:WBGene00048651 21ur-5439 No description available WB:WBGene00048652 21ur-5139 No description available WB:WBGene00048653 21ur-2762 No description available WB:WBGene00048654 21ur-593 Is affected by set-2 based on RNA-seq studies. WB:WBGene00048655 21ur-5248 No description available WB:WBGene00048656 21ur-4708 No description available WB:WBGene00048657 21ur-4934 No description available WB:WBGene00048658 21ur-3335 No description available WB:WBGene00048659 21ur-3856 No description available WB:WBGene00048660 21ur-4698 No description available WB:WBGene00048661 21ur-5349 No description available WB:WBGene00048662 21ur-3458 No description available WB:WBGene00048663 21ur-1110 No description available WB:WBGene00048664 21ur-4178 No description available WB:WBGene00048665 21ur-1286 No description available WB:WBGene00048666 21ur-3713 No description available WB:WBGene00048667 21ur-1730 No description available WB:WBGene00048668 21ur-1024 No description available WB:WBGene00048669 21ur-4893 No description available WB:WBGene00048670 21ur-2241 No description available WB:WBGene00048671 21ur-3969 No description available WB:WBGene00048672 21ur-3730 Enriched in neurons based on RNA-seq studies. WB:WBGene00048673 21ur-4970 No description available WB:WBGene00048674 21ur-2381 No description available WB:WBGene00048675 21ur-4939 No description available WB:WBGene00048676 21ur-4385 Enriched in neurons based on RNA-seq studies. WB:WBGene00048677 21ur-5445 No description available WB:WBGene00048678 21ur-4469 No description available WB:WBGene00048679 21ur-3551 No description available WB:WBGene00048680 21ur-4044 No description available WB:WBGene00048681 21ur-2185 No description available WB:WBGene00048682 21ur-331 No description available WB:WBGene00048683 21ur-2175 Is affected by hmg-4 and spt-16 based on RNA-seq studies. WB:WBGene00048684 21ur-4943 No description available WB:WBGene00048685 21ur-5121 No description available WB:WBGene00048686 21ur-5278 No description available WB:WBGene00048687 21ur-5410 No description available WB:WBGene00048688 21ur-3469 No description available WB:WBGene00048689 21ur-5097 No description available WB:WBGene00048690 21ur-2577 No description available WB:WBGene00048691 21ur-3133 No description available WB:WBGene00048692 21ur-435 No description available WB:WBGene00048693 21ur-4788 No description available WB:WBGene00048694 21ur-1959 No description available WB:WBGene00048695 21ur-1736 No description available WB:WBGene00048696 21ur-314 No description available WB:WBGene00048697 21ur-5300 No description available WB:WBGene00048698 21ur-4168 No description available WB:WBGene00048699 21ur-1486 No description available WB:WBGene00048700 21ur-1893 No description available WB:WBGene00048701 21ur-112 Enriched in neurons based on RNA-seq studies. WB:WBGene00048702 21ur-1967 No description available WB:WBGene00048703 21ur-907 No description available WB:WBGene00048704 21ur-3728 No description available WB:WBGene00048705 21ur-4450 No description available WB:WBGene00048706 21ur-4558 No description available WB:WBGene00048707 21ur-5380 No description available WB:WBGene00048708 21ur-1806 No description available WB:WBGene00048709 21ur-4503 No description available WB:WBGene00048710 21ur-3406 No description available WB:WBGene00048711 21ur-3431 Enriched in neurons based on RNA-seq studies. WB:WBGene00048712 21ur-4584 No description available WB:WBGene00048713 21ur-5018 No description available WB:WBGene00048714 21ur-3708 No description available WB:WBGene00048715 21ur-2908 No description available WB:WBGene00048716 21ur-4989 No description available WB:WBGene00048717 21ur-1469 No description available WB:WBGene00048718 21ur-1014 No description available WB:WBGene00048719 21ur-4413 No description available WB:WBGene00048720 21ur-1407 No description available WB:WBGene00048721 21ur-3992 No description available WB:WBGene00048722 21ur-3583 No description available WB:WBGene00048723 21ur-4474 No description available WB:WBGene00048724 21ur-3002 No description available WB:WBGene00048725 21ur-1534 No description available WB:WBGene00048726 21ur-3045 No description available WB:WBGene00048727 21ur-2971 No description available WB:WBGene00048728 21ur-570 No description available WB:WBGene00048729 21ur-2166 No description available WB:WBGene00048730 21ur-2445 No description available WB:WBGene00048731 21ur-3646 No description available WB:WBGene00048732 21ur-1314 No description available WB:WBGene00048733 21ur-4702 No description available WB:WBGene00048734 21ur-902 No description available WB:WBGene00048735 21ur-1145 No description available WB:WBGene00048736 21ur-476 No description available WB:WBGene00048737 21ur-259 No description available WB:WBGene00048738 21ur-4021 Enriched in neurons based on RNA-seq studies. WB:WBGene00048739 21ur-4928 No description available WB:WBGene00048740 21ur-1562 No description available WB:WBGene00048741 21ur-5102 No description available WB:WBGene00048742 21ur-1853 No description available WB:WBGene00048743 21ur-1290 No description available WB:WBGene00048744 21ur-2901 No description available WB:WBGene00048745 21ur-90 No description available WB:WBGene00048746 21ur-4313 No description available WB:WBGene00048747 21ur-1774 Is affected by Ketamine based on RNA-seq studies. WB:WBGene00048748 21ur-2564 No description available WB:WBGene00048749 21ur-3863 No description available WB:WBGene00048750 21ur-3633 No description available WB:WBGene00048751 21ur-2715 No description available WB:WBGene00048752 21ur-1757 No description available WB:WBGene00048753 21ur-3933 No description available WB:WBGene00048754 21ur-4008 No description available WB:WBGene00048755 21ur-732 No description available WB:WBGene00048756 21ur-1521 No description available WB:WBGene00048757 21ur-340 No description available WB:WBGene00048758 21ur-3947 No description available WB:WBGene00048759 21ur-5423 No description available WB:WBGene00048760 21ur-5362 No description available WB:WBGene00048761 21ur-80 No description available WB:WBGene00048762 21ur-1097 No description available WB:WBGene00048763 21ur-1479 No description available WB:WBGene00048764 21ur-2917 No description available WB:WBGene00048765 21ur-4258 No description available WB:WBGene00048766 21ur-2431 No description available WB:WBGene00048767 21ur-1088 No description available WB:WBGene00048768 21ur-2379 No description available WB:WBGene00048769 21ur-1011 No description available WB:WBGene00048770 21ur-3343 No description available WB:WBGene00048771 21ur-5103 No description available WB:WBGene00048772 21ur-4266 No description available WB:WBGene00048773 21ur-968 No description available WB:WBGene00048774 21ur-2926 No description available WB:WBGene00048775 21ur-642 No description available WB:WBGene00048776 21ur-222 No description available WB:WBGene00048777 21ur-2020 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00048778 21ur-2092 No description available WB:WBGene00048779 21ur-1364 No description available WB:WBGene00048780 21ur-4405 No description available WB:WBGene00048781 21ur-3913 No description available WB:WBGene00048782 21ur-3118 No description available WB:WBGene00048783 21ur-2948 No description available WB:WBGene00048784 21ur-899 No description available WB:WBGene00048785 21ur-5336 No description available WB:WBGene00048786 21ur-62 Enriched in neurons based on RNA-seq studies. WB:WBGene00048787 21ur-2139 No description available WB:WBGene00048788 21ur-4366 No description available WB:WBGene00048789 21ur-2537 No description available WB:WBGene00048790 21ur-5142 No description available WB:WBGene00048791 21ur-4820 No description available WB:WBGene00048792 21ur-2413 No description available WB:WBGene00048793 21ur-2846 No description available WB:WBGene00048794 21ur-1684 No description available WB:WBGene00048795 21ur-168 No description available WB:WBGene00048796 21ur-4251 No description available WB:WBGene00048797 21ur-3182 No description available WB:WBGene00048798 21ur-2272 No description available WB:WBGene00048799 21ur-2014 No description available WB:WBGene00048800 21ur-3395 No description available WB:WBGene00048801 21ur-1901 No description available WB:WBGene00048802 21ur-2573 No description available WB:WBGene00048803 21ur-3097 No description available WB:WBGene00048804 21ur-355 No description available WB:WBGene00048805 21ur-1916 No description available WB:WBGene00048806 21ur-856 No description available WB:WBGene00048807 21ur-2722 No description available WB:WBGene00048808 21ur-4335 Enriched in neurons based on RNA-seq studies. WB:WBGene00048809 21ur-1808 No description available WB:WBGene00048810 21ur-4355 No description available WB:WBGene00048811 21ur-2617 No description available WB:WBGene00048812 21ur-3759 No description available WB:WBGene00048813 21ur-1506 No description available WB:WBGene00048814 21ur-2729 No description available WB:WBGene00048815 21ur-4434 No description available WB:WBGene00048816 21ur-4728 No description available WB:WBGene00048817 21ur-2580 Is affected by eat-2 based on microarray studies. WB:WBGene00048819 21ur-4226 No description available WB:WBGene00048820 21ur-1973 No description available WB:WBGene00048821 21ur-958 No description available WB:WBGene00048822 21ur-601 No description available WB:WBGene00048823 21ur-4295 No description available WB:WBGene00048824 21ur-1451 No description available WB:WBGene00048825 21ur-2212 No description available WB:WBGene00048826 21ur-5119 No description available WB:WBGene00048827 21ur-1771 No description available WB:WBGene00048828 21ur-2620 No description available WB:WBGene00048829 21ur-3606 No description available WB:WBGene00048830 21ur-4352 No description available WB:WBGene00048831 21ur-1554 No description available WB:WBGene00048832 21ur-4344 No description available WB:WBGene00048833 21ur-2505 Enriched in neurons based on RNA-seq studies. WB:WBGene00048834 21ur-4603 No description available WB:WBGene00048835 21ur-3616 No description available WB:WBGene00048836 21ur-3831 No description available WB:WBGene00048837 21ur-3698 No description available WB:WBGene00048838 21ur-1343 No description available WB:WBGene00048839 21ur-1498 No description available WB:WBGene00048840 21ur-3800 No description available WB:WBGene00048841 21ur-1617 No description available WB:WBGene00048842 21ur-4835 No description available WB:WBGene00048843 21ur-683 No description available WB:WBGene00048844 21ur-3587 No description available WB:WBGene00048845 21ur-5147 No description available WB:WBGene00048846 21ur-3839 No description available WB:WBGene00048847 21ur-4247 No description available WB:WBGene00048848 21ur-839 No description available WB:WBGene00048849 21ur-2258 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00048850 21ur-2991 No description available WB:WBGene00048851 21ur-1409 No description available WB:WBGene00048852 21ur-173 No description available WB:WBGene00048853 21ur-1245 No description available WB:WBGene00048854 21ur-269 No description available WB:WBGene00048855 21ur-4721 No description available WB:WBGene00048856 21ur-4416 No description available WB:WBGene00048857 21ur-3739 No description available WB:WBGene00048858 21ur-884 No description available WB:WBGene00048859 21ur-3536 No description available WB:WBGene00048860 21ur-4392 No description available WB:WBGene00048861 21ur-4685 No description available WB:WBGene00048862 21ur-1528 No description available WB:WBGene00048863 21ur-4285 No description available WB:WBGene00048864 21ur-5346 No description available WB:WBGene00048865 21ur-1388 No description available WB:WBGene00048866 21ur-4011 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00048867 21ur-3385 No description available WB:WBGene00048868 21ur-3388 No description available WB:WBGene00048869 21ur-3858 No description available WB:WBGene00048870 21ur-5044 No description available WB:WBGene00048871 21ur-1256 No description available WB:WBGene00048872 21ur-467 No description available WB:WBGene00048873 21ur-3737 No description available WB:WBGene00048874 21ur-1829 No description available WB:WBGene00048875 21ur-1852 No description available WB:WBGene00048876 21ur-252 No description available WB:WBGene00048877 21ur-474 No description available WB:WBGene00048878 21ur-1355 No description available WB:WBGene00048879 21ur-4672 No description available WB:WBGene00048880 21ur-2366 No description available WB:WBGene00048881 21ur-1416 No description available WB:WBGene00048882 21ur-847 No description available WB:WBGene00048883 21ur-2437 No description available WB:WBGene00048884 21ur-2867 No description available WB:WBGene00048885 21ur-1055 No description available WB:WBGene00048886 21ur-2122 No description available WB:WBGene00048887 21ur-1868 No description available WB:WBGene00048888 21ur-4627 No description available WB:WBGene00048889 21ur-3556 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00048890 21ur-3661 No description available WB:WBGene00048891 21ur-17 No description available WB:WBGene00048892 21ur-3626 No description available WB:WBGene00048893 21ur-2428 No description available WB:WBGene00048894 21ur-120 No description available WB:WBGene00048895 21ur-810 No description available WB:WBGene00048896 21ur-2125 No description available WB:WBGene00048897 21ur-270 No description available WB:WBGene00048898 21ur-5049 No description available WB:WBGene00048899 21ur-2430 No description available WB:WBGene00048900 21ur-5295 Enriched in neurons based on RNA-seq studies. WB:WBGene00048901 21ur-4909 No description available WB:WBGene00048902 21ur-1313 No description available WB:WBGene00048903 21ur-4744 No description available WB:WBGene00048904 21ur-4288 No description available WB:WBGene00048905 21ur-4651 No description available WB:WBGene00048906 21ur-3668 No description available WB:WBGene00048907 21ur-4630 No description available WB:WBGene00048908 21ur-1337 No description available WB:WBGene00048909 21ur-2628 No description available WB:WBGene00048910 21ur-4423 Enriched in neurons based on RNA-seq studies. WB:WBGene00048911 21ur-121 No description available WB:WBGene00048912 21ur-3746 No description available WB:WBGene00048913 21ur-2829 No description available WB:WBGene00048914 21ur-758 Enriched in neurons based on RNA-seq studies. WB:WBGene00048915 21ur-4809 No description available WB:WBGene00048916 21ur-4527 No description available WB:WBGene00048917 21ur-262 No description available WB:WBGene00048918 21ur-541 No description available WB:WBGene00048919 21ur-2044 No description available WB:WBGene00048920 21ur-5190 No description available WB:WBGene00048921 21ur-3878 No description available WB:WBGene00048922 21ur-730 No description available WB:WBGene00048923 21ur-275 No description available WB:WBGene00048924 21ur-3689 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00048925 21ur-4363 No description available WB:WBGene00048926 21ur-3300 No description available WB:WBGene00048927 21ur-1192 No description available WB:WBGene00048928 21ur-4468 No description available WB:WBGene00048929 21ur-5328 No description available WB:WBGene00048930 21ur-722 No description available WB:WBGene00048931 21ur-4105 No description available WB:WBGene00048932 21ur-580 No description available WB:WBGene00048933 21ur-4982 No description available WB:WBGene00048934 21ur-3507 Enriched in neurons based on RNA-seq studies. WB:WBGene00048935 21ur-1130 No description available WB:WBGene00048936 21ur-1677 Enriched in neurons based on RNA-seq studies. WB:WBGene00048937 21ur-3907 No description available WB:WBGene00048938 21ur-130 No description available WB:WBGene00048939 21ur-3989 No description available WB:WBGene00048940 21ur-3194 Enriched in neurons based on RNA-seq studies. WB:WBGene00048941 21ur-2738 No description available WB:WBGene00048942 21ur-4877 No description available WB:WBGene00048943 21ur-3765 No description available WB:WBGene00048944 21ur-1331 No description available WB:WBGene00048945 21ur-2217 No description available WB:WBGene00048946 21ur-5007 No description available WB:WBGene00048947 21ur-2288 No description available WB:WBGene00048948 21ur-1795 No description available WB:WBGene00048949 21ur-2499 No description available WB:WBGene00048950 21ur-2340 No description available WB:WBGene00048951 21ur-1139 No description available WB:WBGene00048952 21ur-3784 No description available WB:WBGene00048953 21ur-1151 No description available WB:WBGene00048954 21ur-4010 No description available WB:WBGene00048955 21ur-4129 No description available WB:WBGene00048956 21ur-1434 No description available WB:WBGene00048957 21ur-1944 No description available WB:WBGene00048958 21ur-853 No description available WB:WBGene00048959 21ur-838 No description available WB:WBGene00048960 21ur-229 No description available WB:WBGene00048961 21ur-1047 No description available WB:WBGene00048962 21ur-3379 No description available WB:WBGene00048963 21ur-1971 No description available WB:WBGene00048964 21ur-2677 No description available WB:WBGene00048965 21ur-1008 No description available WB:WBGene00048966 21ur-1062 No description available WB:WBGene00048967 21ur-5152 No description available WB:WBGene00048968 21ur-3325 No description available WB:WBGene00048969 21ur-511 Enriched in neurons based on RNA-seq studies. WB:WBGene00048970 21ur-2651 No description available WB:WBGene00048971 21ur-209 No description available WB:WBGene00048972 21ur-1341 No description available WB:WBGene00048973 21ur-1932 No description available WB:WBGene00048974 21ur-3281 No description available WB:WBGene00048975 21ur-1408 No description available WB:WBGene00048976 21ur-4633 No description available WB:WBGene00048977 21ur-893 No description available WB:WBGene00048978 21ur-4432 No description available WB:WBGene00048979 21ur-1947 No description available WB:WBGene00048980 21ur-2321 No description available WB:WBGene00048981 21ur-661 No description available WB:WBGene00048982 21ur-3429 No description available WB:WBGene00048983 21ur-4563 No description available WB:WBGene00048984 21ur-2105 No description available WB:WBGene00048985 21ur-2773 No description available WB:WBGene00048986 21ur-704 No description available WB:WBGene00048987 21ur-2047 No description available WB:WBGene00048988 21ur-2110 No description available WB:WBGene00048989 21ur-137 No description available WB:WBGene00048990 21ur-509 No description available WB:WBGene00048991 21ur-3624 No description available WB:WBGene00048992 21ur-3550 No description available WB:WBGene00048993 21ur-4154 No description available WB:WBGene00048994 21ur-3822 No description available WB:WBGene00048995 21ur-942 No description available WB:WBGene00048996 21ur-1262 No description available WB:WBGene00048997 21ur-2133 No description available WB:WBGene00048998 21ur-2895 No description available WB:WBGene00048999 21ur-4663 No description available WB:WBGene00049000 21ur-3830 No description available WB:WBGene00049001 21ur-3341 No description available WB:WBGene00049002 21ur-4775 No description available WB:WBGene00049003 21ur-5055 Enriched in neurons based on RNA-seq studies. WB:WBGene00049004 21ur-3357 No description available WB:WBGene00049005 21ur-3446 No description available WB:WBGene00049006 21ur-1643 No description available WB:WBGene00049007 21ur-2572 No description available WB:WBGene00049008 21ur-4257 No description available WB:WBGene00049009 21ur-5132 No description available WB:WBGene00049010 21ur-921 No description available WB:WBGene00049011 21ur-324 No description available WB:WBGene00049012 21ur-3569 No description available WB:WBGene00049013 21ur-933 No description available WB:WBGene00049014 21ur-1549 No description available WB:WBGene00049015 21ur-4658 No description available WB:WBGene00049016 21ur-1205 No description available WB:WBGene00049017 21ur-3128 No description available WB:WBGene00049018 21ur-3677 No description available WB:WBGene00049019 21ur-287 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00049020 21ur-1559 No description available WB:WBGene00049021 21ur-1472 No description available WB:WBGene00049022 21ur-3595 No description available WB:WBGene00049023 21ur-1392 No description available WB:WBGene00049024 21ur-3979 No description available WB:WBGene00049025 21ur-4265 No description available WB:WBGene00049026 21ur-3414 No description available WB:WBGene00049027 21ur-2516 Enriched in neurons based on RNA-seq studies. WB:WBGene00049028 21ur-1929 No description available WB:WBGene00049029 21ur-6 No description available WB:WBGene00049030 21ur-4799 No description available WB:WBGene00049031 21ur-2610 No description available WB:WBGene00049032 21ur-3686 No description available WB:WBGene00049033 21ur-3212 No description available WB:WBGene00049034 21ur-3072 No description available WB:WBGene00049035 21ur-2336 No description available WB:WBGene00049036 21ur-4490 Enriched in neurons based on RNA-seq studies. WB:WBGene00049037 21ur-1874 No description available WB:WBGene00049038 21ur-1269 No description available WB:WBGene00049039 21ur-2863 No description available WB:WBGene00049040 21ur-2600 No description available WB:WBGene00049041 21ur-4078 No description available WB:WBGene00049042 21ur-2312 No description available WB:WBGene00049043 21ur-4072 No description available WB:WBGene00049044 21ur-1780 No description available WB:WBGene00049045 21ur-3848 No description available WB:WBGene00049046 21ur-1983 No description available WB:WBGene00049047 21ur-2051 No description available WB:WBGene00049048 21ur-1540 No description available WB:WBGene00049049 21ur-1633 No description available WB:WBGene00049050 21ur-1270 No description available WB:WBGene00049051 21ur-1624 No description available WB:WBGene00049052 21ur-2627 No description available WB:WBGene00049053 21ur-3893 No description available WB:WBGene00049054 21ur-4880 No description available WB:WBGene00049055 21ur-118 No description available WB:WBGene00049056 21ur-5062 No description available WB:WBGene00049057 21ur-404 No description available WB:WBGene00049058 21ur-4800 Enriched in neurons based on RNA-seq studies. WB:WBGene00049059 21ur-3240 No description available WB:WBGene00049060 21ur-2463 No description available WB:WBGene00049061 21ur-2609 No description available WB:WBGene00049062 21ur-2029 No description available WB:WBGene00049063 21ur-3148 No description available WB:WBGene00049064 21ur-2230 No description available WB:WBGene00049065 21ur-3715 No description available WB:WBGene00049066 21ur-63 No description available WB:WBGene00049067 21ur-3608 No description available WB:WBGene00049068 21ur-3098 No description available WB:WBGene00049069 21ur-3022 No description available WB:WBGene00049070 21ur-1374 Enriched in neurons based on RNA-seq studies. WB:WBGene00049071 21ur-5407 No description available WB:WBGene00049072 21ur-186 No description available WB:WBGene00049073 21ur-2223 No description available WB:WBGene00049074 21ur-3685 No description available WB:WBGene00049075 21ur-329 No description available WB:WBGene00049076 21ur-1401 No description available WB:WBGene00049077 21ur-2367 No description available WB:WBGene00049078 21ur-3825 No description available WB:WBGene00049079 21ur-4082 Enriched in neurons based on RNA-seq studies. WB:WBGene00049080 21ur-2526 No description available WB:WBGene00049081 21ur-2806 No description available WB:WBGene00049082 21ur-2803 No description available WB:WBGene00049083 21ur-2266 No description available WB:WBGene00049084 21ur-1229 Is affected by lem-2; emr-1; and nfki-1 based on RNA-seq studies. WB:WBGene00049085 21ur-4918 No description available WB:WBGene00049086 21ur-2964 No description available WB:WBGene00049087 21ur-3057 No description available WB:WBGene00049088 21ur-2619 No description available WB:WBGene00049089 21ur-2073 No description available WB:WBGene00049090 21ur-3476 Enriched in neurons based on RNA-seq studies. WB:WBGene00049091 21ur-4384 No description available WB:WBGene00049092 21ur-2634 No description available WB:WBGene00049093 21ur-4250 No description available WB:WBGene00049094 21ur-1476 Enriched in neurons based on RNA-seq studies. WB:WBGene00049095 21ur-43 No description available WB:WBGene00049096 21ur-3220 No description available WB:WBGene00049097 21ur-1822 No description available WB:WBGene00049098 21ur-3124 No description available WB:WBGene00049099 21ur-679 No description available WB:WBGene00049100 21ur-5011 No description available WB:WBGene00049101 21ur-864 No description available WB:WBGene00049102 21ur-5317 No description available WB:WBGene00049103 21ur-3557 No description available WB:WBGene00049104 21ur-741 Enriched in neurons based on RNA-seq studies. WB:WBGene00049105 21ur-3720 No description available WB:WBGene00049106 21ur-5072 No description available WB:WBGene00049107 21ur-2607 No description available WB:WBGene00049108 21ur-4612 No description available WB:WBGene00049109 21ur-2325 No description available WB:WBGene00049110 21ur-4036 No description available WB:WBGene00049111 21ur-3792 No description available WB:WBGene00049112 21ur-5378 No description available WB:WBGene00049113 21ur-2590 Enriched in neurons based on RNA-seq studies. WB:WBGene00049114 21ur-4864 No description available WB:WBGene00049115 21ur-59 No description available WB:WBGene00049116 21ur-236 No description available WB:WBGene00049117 21ur-4649 No description available WB:WBGene00049118 21ur-4439 No description available WB:WBGene00049119 21ur-2644 No description available WB:WBGene00049120 21ur-737 No description available WB:WBGene00049121 21ur-303 No description available WB:WBGene00049122 21ur-693 Is affected by daf-2 based on microarray studies. WB:WBGene00049123 21ur-1382 No description available WB:WBGene00049124 21ur-1160 No description available WB:WBGene00049125 21ur-3964 No description available WB:WBGene00049126 21ur-5185 No description available WB:WBGene00049127 21ur-3846 No description available WB:WBGene00049128 21ur-5202 No description available WB:WBGene00049129 21ur-965 No description available WB:WBGene00049130 21ur-2389 No description available WB:WBGene00049131 21ur-5389 No description available WB:WBGene00049132 21ur-2013 No description available WB:WBGene00049133 21ur-129 No description available WB:WBGene00049134 21ur-179 No description available WB:WBGene00049135 21ur-860 No description available WB:WBGene00049136 21ur-1231 Enriched in neurons based on RNA-seq studies. WB:WBGene00049137 21ur-4303 No description available WB:WBGene00049138 21ur-713 No description available WB:WBGene00049139 21ur-4009 No description available WB:WBGene00049140 21ur-3957 No description available WB:WBGene00049141 21ur-3484 No description available WB:WBGene00049142 21ur-3290 No description available WB:WBGene00049143 21ur-1504 Is affected by set-2 based on RNA-seq studies. WB:WBGene00049144 21ur-4138 No description available WB:WBGene00049145 21ur-3883 No description available WB:WBGene00049146 21ur-3939 No description available WB:WBGene00049147 21ur-4768 No description available WB:WBGene00049148 21ur-4978 No description available WB:WBGene00049149 21ur-4206 Is affected by spt-16 and rnp-6 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies. WB:WBGene00049150 21ur-4065 Enriched in neurons based on RNA-seq studies. WB:WBGene00049151 21ur-3741 No description available WB:WBGene00049152 21ur-3228 No description available WB:WBGene00049153 21ur-3202 No description available WB:WBGene00049154 21ur-2482 Enriched in neurons based on RNA-seq studies. WB:WBGene00049155 21ur-1615 Is affected by ints-9 and set-2 based on RNA-seq studies. WB:WBGene00049156 21ur-4273 No description available WB:WBGene00049157 21ur-3980 No description available WB:WBGene00049158 21ur-3310 No description available WB:WBGene00049159 21ur-3496 Enriched in neurons based on RNA-seq studies. WB:WBGene00049160 21ur-995 No description available WB:WBGene00049161 21ur-2857 No description available WB:WBGene00049162 21ur-3752 No description available WB:WBGene00049163 21ur-2263 No description available WB:WBGene00049164 21ur-1443 No description available WB:WBGene00049165 21ur-4379 Enriched in neurons based on RNA-seq studies. WB:WBGene00049166 21ur-614 No description available WB:WBGene00049167 21ur-1639 No description available WB:WBGene00049168 21ur-172 No description available WB:WBGene00049169 21ur-3945 No description available WB:WBGene00049170 21ur-293 No description available WB:WBGene00049171 21ur-381 No description available WB:WBGene00049172 21ur-4525 No description available WB:WBGene00049173 21ur-2054 No description available WB:WBGene00049174 21ur-2118 No description available WB:WBGene00049175 21ur-4881 No description available WB:WBGene00049176 21ur-3012 No description available WB:WBGene00049177 21ur-3104 No description available WB:WBGene00049178 21ur-3153 Enriched in neurons based on RNA-seq studies. WB:WBGene00049179 21ur-504 No description available WB:WBGene00049180 21ur-443 No description available WB:WBGene00049181 21ur-448 No description available WB:WBGene00049182 21ur-1657 No description available WB:WBGene00049183 21ur-4647 No description available WB:WBGene00049184 21ur-4998 No description available WB:WBGene00049185 21ur-91 No description available WB:WBGene00049186 21ur-3276 No description available WB:WBGene00049187 21ur-4096 No description available WB:WBGene00049188 21ur-4483 No description available WB:WBGene00049189 21ur-4991 Is affected by set-2 based on RNA-seq studies. WB:WBGene00049190 21ur-1802 No description available WB:WBGene00049191 21ur-3350 No description available WB:WBGene00049192 21ur-1898 No description available WB:WBGene00049193 21ur-916 No description available WB:WBGene00049194 21ur-837 No description available WB:WBGene00049195 21ur-2755 No description available WB:WBGene00049196 21ur-3972 No description available WB:WBGene00049197 21ur-3650 No description available WB:WBGene00049198 21ur-4487 No description available WB:WBGene00049199 21ur-2062 No description available WB:WBGene00049200 21ur-2521 No description available WB:WBGene00049201 21ur-2879 No description available WB:WBGene00049202 21ur-3538 No description available WB:WBGene00049203 21ur-1563 No description available WB:WBGene00049204 21ur-427 No description available WB:WBGene00049205 21ur-3898 No description available WB:WBGene00049206 21ur-4947 No description available WB:WBGene00049207 21ur-3199 No description available WB:WBGene00049208 21ur-595 No description available WB:WBGene00049209 21ur-521 No description available WB:WBGene00049210 21ur-2406 No description available WB:WBGene00049211 21ur-2271 No description available WB:WBGene00049212 21ur-5082 No description available WB:WBGene00049213 21ur-5025 No description available WB:WBGene00049214 21ur-2464 No description available WB:WBGene00049215 21ur-5411 Is affected by daf-2 based on microarray studies. WB:WBGene00049216 21ur-5006 No description available WB:WBGene00049217 21ur-4562 No description available WB:WBGene00049218 21ur-2765 Enriched in neurons based on RNA-seq studies. WB:WBGene00049219 21ur-2156 No description available WB:WBGene00049220 21ur-4530 No description available WB:WBGene00049221 21ur-149 No description available WB:WBGene00049222 21ur-1809 No description available WB:WBGene00049223 21ur-70 No description available WB:WBGene00049224 21ur-2791 No description available WB:WBGene00049225 21ur-777 No description available WB:WBGene00049226 21ur-1722 No description available WB:WBGene00049227 21ur-3838 No description available WB:WBGene00049228 21ur-3058 Is affected by set-2; hda-2; and etr-1 based on RNA-seq studies. WB:WBGene00049229 21ur-3932 No description available WB:WBGene00049230 21ur-2906 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00049231 21ur-3170 No description available WB:WBGene00049232 21ur-1817 No description available WB:WBGene00049233 21ur-4571 No description available WB:WBGene00049234 21ur-3171 No description available WB:WBGene00049235 21ur-4395 No description available WB:WBGene00049236 21ur-2980 No description available WB:WBGene00049237 21ur-1329 No description available WB:WBGene00049238 21ur-598 No description available WB:WBGene00049239 21ur-3502 No description available WB:WBGene00049240 21ur-3372 Expressed in germ line. WB:WBGene00049241 21ur-3517 Enriched in neurons based on RNA-seq studies. WB:WBGene00049242 21ur-5158 No description available WB:WBGene00049243 21ur-1025 No description available WB:WBGene00049244 21ur-3393 No description available WB:WBGene00049245 21ur-1758 No description available WB:WBGene00049246 21ur-221 No description available WB:WBGene00049247 21ur-5372 No description available WB:WBGene00049248 21ur-3110 Is affected by several genes including set-2; let-418; and chd-3 based on RNA-seq studies. WB:WBGene00049249 21ur-2333 No description available WB:WBGene00049250 21ur-4528 No description available WB:WBGene00049251 21ur-1285 No description available WB:WBGene00049252 21ur-5230 Enriched in neurons based on RNA-seq studies. WB:WBGene00049253 21ur-1882 No description available WB:WBGene00049254 21ur-5030 No description available WB:WBGene00049255 21ur-5237 No description available WB:WBGene00049256 21ur-1021 No description available WB:WBGene00049257 21ur-1578 No description available WB:WBGene00049258 21ur-1707 No description available WB:WBGene00049259 21ur-3983 No description available WB:WBGene00049260 21ur-4110 No description available WB:WBGene00049261 21ur-2684 No description available WB:WBGene00049262 21ur-2378 No description available WB:WBGene00049263 21ur-2492 No description available WB:WBGene00049264 21ur-3489 No description available WB:WBGene00049265 21ur-3166 No description available WB:WBGene00049266 21ur-2476 No description available WB:WBGene00049267 21ur-3524 No description available WB:WBGene00049268 21ur-1106 No description available WB:WBGene00049269 21ur-174 No description available WB:WBGene00049270 21ur-4892 No description available WB:WBGene00049271 21ur-5306 No description available WB:WBGene00049272 21ur-3444 No description available WB:WBGene00049273 21ur-2145 No description available WB:WBGene00049274 21ur-4280 No description available WB:WBGene00049275 21ur-332 No description available WB:WBGene00049276 21ur-3617 No description available WB:WBGene00049277 21ur-4415 No description available WB:WBGene00049278 21ur-5267 No description available WB:WBGene00049279 21ur-819 No description available WB:WBGene00049280 21ur-4199 Enriched in neurons based on RNA-seq studies. WB:WBGene00049281 21ur-1831 No description available WB:WBGene00049282 21ur-1779 No description available WB:WBGene00049283 21ur-650 No description available WB:WBGene00049284 21ur-2399 No description available WB:WBGene00049285 21ur-384 No description available WB:WBGene00049286 21ur-4306 No description available WB:WBGene00049287 21ur-3993 No description available WB:WBGene00049288 21ur-4796 No description available WB:WBGene00049289 21ur-4248 No description available WB:WBGene00049290 21ur-3968 No description available WB:WBGene00049291 21ur-412 No description available WB:WBGene00049292 21ur-5298 No description available WB:WBGene00049293 21ur-592 No description available WB:WBGene00049294 21ur-1471 No description available WB:WBGene00049295 21ur-2777 No description available WB:WBGene00049296 21ur-4962 No description available WB:WBGene00049297 21ur-2176 No description available WB:WBGene00049298 21ur-4690 No description available WB:WBGene00049299 21ur-602 No description available WB:WBGene00049300 21ur-87 No description available WB:WBGene00049301 21ur-4871 No description available WB:WBGene00049302 21ur-4695 No description available WB:WBGene00049303 21ur-3580 No description available WB:WBGene00049304 21ur-4216 No description available WB:WBGene00049305 21ur-3693 No description available WB:WBGene00049306 21ur-2032 No description available WB:WBGene00049307 21ur-787 Is affected by semo-1 based on RNA-seq studies. WB:WBGene00049308 21ur-3066 No description available WB:WBGene00049309 21ur-947 No description available WB:WBGene00049310 21ur-522 No description available WB:WBGene00049311 21ur-5341 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00049312 21ur-2316 No description available WB:WBGene00049313 21ur-2039 No description available WB:WBGene00049314 21ur-2789 No description available WB:WBGene00049315 21ur-2004 No description available WB:WBGene00049316 21ur-1892 No description available WB:WBGene00049317 21ur-2898 No description available WB:WBGene00049318 21ur-3874 No description available WB:WBGene00049319 21ur-2561 No description available WB:WBGene00049320 21ur-4296 No description available WB:WBGene00049321 21ur-442 No description available WB:WBGene00049322 21ur-784 Enriched in neurons based on RNA-seq studies. WB:WBGene00049323 21ur-1992 No description available WB:WBGene00049324 21ur-2534 No description available WB:WBGene00049325 21ur-1982 No description available WB:WBGene00049326 21ur-1588 No description available WB:WBGene00049327 21ur-3437 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00049328 21ur-2818 No description available WB:WBGene00049329 21ur-2198 No description available WB:WBGene00049330 21ur-5247 No description available WB:WBGene00049331 21ur-5095 No description available WB:WBGene00049332 21ur-315 No description available WB:WBGene00049333 21ur-2910 No description available WB:WBGene00049334 21ur-4935 No description available WB:WBGene00049335 21ur-3857 No description available WB:WBGene00049336 21ur-2348 Enriched in neurons based on RNA-seq studies. WB:WBGene00049337 21ur-3439 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00049338 21ur-668 No description available WB:WBGene00049339 21ur-1616 No description available WB:WBGene00049340 21ur-3203 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00049341 21ur-2951 No description available WB:WBGene00049342 21ur-924 No description available WB:WBGene00049343 21ur-4585 No description available WB:WBGene00049344 21ur-2540 No description available WB:WBGene00049345 21ur-4701 No description available WB:WBGene00049346 21ur-2055 No description available WB:WBGene00049347 21ur-4903 No description available WB:WBGene00049348 21ur-550 No description available WB:WBGene00049349 21ur-1350 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00049350 21ur-5162 No description available WB:WBGene00049351 21ur-1706 No description available WB:WBGene00049352 21ur-4157 No description available WB:WBGene00049353 21ur-3065 No description available WB:WBGene00049354 21ur-345 No description available WB:WBGene00049355 21ur-1044 No description available WB:WBGene00049356 21ur-4079 No description available WB:WBGene00049357 21ur-4868 No description available WB:WBGene00049358 21ur-5034 No description available WB:WBGene00049359 21ur-1116 No description available WB:WBGene00049360 21ur-3265 No description available WB:WBGene00049361 21ur-4781 No description available WB:WBGene00049362 21ur-4241 No description available WB:WBGene00049363 21ur-3400 No description available WB:WBGene00049364 21ur-72 No description available WB:WBGene00049365 21ur-165 No description available WB:WBGene00049366 21ur-2843 Enriched in neurons based on RNA-seq studies. WB:WBGene00049367 21ur-1903 No description available WB:WBGene00049368 21ur-2958 No description available WB:WBGene00049369 21ur-2207 No description available WB:WBGene00049370 21ur-858 No description available WB:WBGene00049371 21ur-4181 No description available WB:WBGene00049372 21ur-1173 Enriched in neurons based on RNA-seq studies. WB:WBGene00049373 21ur-1363 Enriched in neurons based on RNA-seq studies. WB:WBGene00049374 21ur-2824 No description available WB:WBGene00049375 21ur-1034 No description available WB:WBGene00049376 21ur-3643 No description available WB:WBGene00049377 21ur-3576 No description available WB:WBGene00049378 21ur-1575 No description available WB:WBGene00049379 21ur-696 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00049380 21ur-152 No description available WB:WBGene00049381 21ur-565 No description available WB:WBGene00049382 21ur-4367 No description available WB:WBGene00049383 21ur-4969 No description available WB:WBGene00049384 21ur-1507 No description available WB:WBGene00049385 21ur-18 No description available WB:WBGene00049386 21ur-3084 No description available WB:WBGene00049387 21ur-641 No description available WB:WBGene00049388 21ur-801 No description available WB:WBGene00049389 21ur-4959 No description available WB:WBGene00049390 21ur-1216 No description available WB:WBGene00049391 21ur-200 No description available WB:WBGene00049392 21ur-5141 No description available WB:WBGene00049393 21ur-2893 Is affected by lem-2; emr-1; and semo-1 based on RNA-seq studies. WB:WBGene00049394 21ur-4856 No description available WB:WBGene00049395 21ur-2927 No description available WB:WBGene00049396 21ur-3823 No description available WB:WBGene00049397 21ur-3605 No description available WB:WBGene00049398 21ur-3914 No description available WB:WBGene00049399 21ur-1535 No description available WB:WBGene00049400 21ur-3793 Enriched in neurons based on RNA-seq studies. WB:WBGene00049401 21ur-5131 No description available WB:WBGene00049402 21ur-5122 No description available WB:WBGene00049403 21ur-280 No description available WB:WBGene00049404 21ur-322 No description available WB:WBGene00049405 21ur-4345 No description available WB:WBGene00049406 21ur-4406 No description available WB:WBGene00049407 21ur-5117 No description available WB:WBGene00049408 21ur-4999 No description available WB:WBGene00049409 21ur-4149 No description available WB:WBGene00049410 21ur-4688 No description available WB:WBGene00049411 21ur-3091 No description available WB:WBGene00049412 21ur-1300 No description available WB:WBGene00049413 21ur-167 No description available WB:WBGene00049414 21ur-898 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00049415 21ur-2265 No description available WB:WBGene00049416 21ur-1516 No description available WB:WBGene00049417 21ur-3269 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00049418 21ur-5167 No description available WB:WBGene00049419 21ur-136 No description available WB:WBGene00049420 21ur-2747 No description available WB:WBGene00049421 21ur-217 No description available WB:WBGene00049422 21ur-2414 No description available WB:WBGene00049423 21ur-4444 No description available WB:WBGene00049424 21ur-2446 Is affected by hmg-3 and spt-16 based on RNA-seq studies. WB:WBGene00049425 21ur-5436 No description available WB:WBGene00049426 21ur-4334 No description available WB:WBGene00049427 21ur-4227 No description available WB:WBGene00049428 21ur-875 No description available WB:WBGene00049429 21ur-2101 No description available WB:WBGene00049430 21ur-3775 No description available WB:WBGene00049431 21ur-2382 No description available WB:WBGene00049432 21ur-2457 No description available WB:WBGene00049433 21ur-1425 No description available WB:WBGene00049434 21ur-982 No description available WB:WBGene00049435 21ur-1452 No description available WB:WBGene00049436 21ur-4578 No description available WB:WBGene00049437 21ur-107 No description available WB:WBGene00049438 21ur-2240 No description available WB:WBGene00049439 21ur-634 No description available WB:WBGene00049440 21ur-4602 No description available WB:WBGene00049441 21ur-2259 No description available WB:WBGene00049443 21ur-1529 No description available WB:WBGene00049444 21ur-2088 No description available WB:WBGene00049445 21ur-2183 Enriched in neurons based on RNA-seq studies. WB:WBGene00049446 21ur-857 No description available WB:WBGene00049447 21ur-1772 No description available WB:WBGene00049448 21ur-3697 No description available WB:WBGene00049449 21ur-960 No description available WB:WBGene00049450 21ur-1344 No description available WB:WBGene00049451 21ur-3363 No description available WB:WBGene00049452 21ur-1376 No description available WB:WBGene00049453 21ur-2093 No description available WB:WBGene00049454 21ur-3535 No description available WB:WBGene00049455 21ur-1951 No description available WB:WBGene00049456 21ur-950 No description available WB:WBGene00049457 21ur-2211 No description available WB:WBGene00049458 21ur-2581 No description available WB:WBGene00049459 21ur-4290 No description available WB:WBGene00049460 21ur-2065 No description available WB:WBGene00049461 21ur-1322 No description available WB:WBGene00049462 21ur-3319 No description available WB:WBGene00049463 21ur-4429 No description available WB:WBGene00049464 21ur-2473 No description available WB:WBGene00049465 21ur-4679 Is affected by lem-2; emr-1; and hmg-3 based on RNA-seq studies. WB:WBGene00049466 21ur-4789 No description available WB:WBGene00049467 21ur-2579 No description available WB:WBGene00049468 21ur-1280 No description available WB:WBGene00049469 21ur-827 Enriched in neurons based on RNA-seq studies. WB:WBGene00049470 21ur-1041 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00049471 21ur-4169 No description available WB:WBGene00049472 21ur-4471 No description available WB:WBGene00049473 21ur-4422 No description available WB:WBGene00049474 21ur-1224 No description available WB:WBGene00049475 21ur-5352 No description available WB:WBGene00049476 21ur-705 No description available WB:WBGene00049477 21ur-3309 No description available WB:WBGene00049478 21ur-1999 No description available WB:WBGene00049479 21ur-4752 No description available WB:WBGene00049480 21ur-2576 No description available WB:WBGene00049481 21ur-3639 No description available WB:WBGene00049482 21ur-5017 No description available WB:WBGene00049483 21ur-1964 No description available WB:WBGene00049484 21ur-3042 Enriched in neurons based on RNA-seq studies. WB:WBGene00049485 21ur-1490 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00049486 21ur-34 No description available WB:WBGene00049487 21ur-432 No description available WB:WBGene00049488 21ur-1764 Enriched in neurons based on RNA-seq studies. WB:WBGene00049489 21ur-111 Enriched in neurons based on RNA-seq studies. WB:WBGene00049490 21ur-759 No description available WB:WBGene00049491 21ur-3705 No description available WB:WBGene00049492 21ur-1082 No description available WB:WBGene00049493 21ur-2740 No description available WB:WBGene00049494 21ur-2832 No description available WB:WBGene00049495 21ur-4559 No description available WB:WBGene00049496 21ur-3340 No description available WB:WBGene00049497 21ur-1144 No description available WB:WBGene00049498 21ur-1123 No description available WB:WBGene00049499 21ur-3430 No description available WB:WBGene00049500 21ur-1670 No description available WB:WBGene00049501 21ur-5351 No description available WB:WBGene00049502 21ur-1417 No description available WB:WBGene00049503 21ur-3978 No description available WB:WBGene00049504 21ur-5329 No description available WB:WBGene00049505 21ur-2718 No description available WB:WBGene00049506 21ur-3229 No description available WB:WBGene00049507 21ur-2970 No description available WB:WBGene00049508 21ur-1917 No description available WB:WBGene00049509 21ur-1074 No description available WB:WBGene00049510 21ur-4414 No description available WB:WBGene00049511 21ur-2735 No description available WB:WBGene00049512 21ur-407 No description available WB:WBGene00049513 21ur-190 No description available WB:WBGene00049514 21ur-1805 Enriched in neurons based on RNA-seq studies. WB:WBGene00049515 21ur-5337 No description available WB:WBGene00049516 21ur-2394 Is affected by unc-70 based on RNA-seq studies. WB:WBGene00049517 21ur-1238 No description available WB:WBGene00049518 21ur-4323 No description available WB:WBGene00049519 21ur-2588 No description available WB:WBGene00049520 21ur-2721 No description available WB:WBGene00049521 21ur-54 No description available WB:WBGene00049522 21ur-1729 No description available WB:WBGene00049523 21ur-731 No description available WB:WBGene00049524 21ur-2724 No description available WB:WBGene00049525 21ur-901 No description available WB:WBGene00049526 21ur-1485 No description available WB:WBGene00049527 21ur-4007 No description available WB:WBGene00049528 21ur-1666 No description available WB:WBGene00049529 21ur-3634 No description available WB:WBGene00049530 21ur-3946 No description available WB:WBGene00049531 21ur-1096 No description available WB:WBGene00049532 21ur-5101 No description available WB:WBGene00049533 21ur-1435 No description available WB:WBGene00049534 21ur-761 No description available WB:WBGene00049535 21ur-3815 No description available WB:WBGene00049536 21ur-4810 No description available WB:WBGene00049537 21ur-1089 No description available WB:WBGene00049538 21ur-5363 No description available WB:WBGene00049539 21ur-1167 No description available WB:WBGene00049540 21ur-4732 No description available WB:WBGene00049541 21ur-3342 No description available WB:WBGene00049542 21ur-5201 No description available WB:WBGene00049543 21ur-1821 No description available WB:WBGene00049544 21ur-2616 No description available WB:WBGene00049545 21ur-1012 No description available WB:WBGene00049546 21ur-1697 No description available WB:WBGene00049547 21ur-1813 No description available WB:WBGene00049548 21ur-5179 No description available WB:WBGene00049549 21ur-1278 No description available WB:WBGene00049550 21ur-3847 No description available WB:WBGene00049551 21ur-4137 Is affected by daf-2 based on microarray studies. WB:WBGene00049552 21ur-1422 No description available WB:WBGene00049553 21ur-1261 No description available WB:WBGene00049554 21ur-3990 No description available WB:WBGene00049555 21ur-2308 No description available WB:WBGene00049556 21ur-5151 No description available WB:WBGene00049557 21ur-3758 No description available WB:WBGene00049558 21ur-3873 No description available WB:WBGene00049559 21ur-4476 Is affected by daf-2 based on microarray studies. WB:WBGene00049560 21ur-1003 Enriched in neurons based on RNA-seq studies. WB:WBGene00049561 21ur-826 No description available WB:WBGene00049562 21ur-3326 No description available WB:WBGene00049563 21ur-588 No description available WB:WBGene00049564 21ur-2694 No description available WB:WBGene00049565 21ur-2853 No description available WB:WBGene00049566 21ur-1233 No description available WB:WBGene00049567 21ur-4048 No description available WB:WBGene00049568 21ur-714 No description available WB:WBGene00049569 21ur-4779 Enriched in neurons based on RNA-seq studies. WB:WBGene00049570 21ur-5386 No description available WB:WBGene00049571 21ur-2937 No description available WB:WBGene00049572 21ur-5451 No description available WB:WBGene00049573 21ur-2276 No description available WB:WBGene00049574 21ur-998 No description available WB:WBGene00049575 21ur-3103 No description available WB:WBGene00049576 21ur-4635 Is affected by daf-2 based on microarray studies. WB:WBGene00049577 21ur-1029 No description available WB:WBGene00049578 21ur-1979 No description available WB:WBGene00049579 21ur-2407 No description available WB:WBGene00049580 21ur-4387 No description available WB:WBGene00049581 21ur-966 No description available WB:WBGene00049582 21ur-2352 No description available WB:WBGene00049583 21ur-5180 No description available WB:WBGene00049584 21ur-1818 No description available WB:WBGene00049585 21ur-1776 No description available WB:WBGene00049586 21ur-307 No description available WB:WBGene00049587 21ur-4097 No description available WB:WBGene00049588 21ur-4264 No description available WB:WBGene00049589 21ur-4486 No description available WB:WBGene00049590 21ur-4861 No description available WB:WBGene00049591 21ur-1188 No description available WB:WBGene00049592 21ur-1227 No description available WB:WBGene00049593 21ur-3497 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00049594 21ur-300 No description available WB:WBGene00049595 21ur-1499 No description available WB:WBGene00049596 21ur-3938 No description available WB:WBGene00049597 21ur-3821 No description available WB:WBGene00049598 21ur-4762 No description available WB:WBGene00049599 21ur-5010 No description available WB:WBGene00049600 21ur-4230 No description available WB:WBGene00049601 21ur-3359 No description available WB:WBGene00049602 21ur-662 No description available WB:WBGene00049603 21ur-2460 No description available WB:WBGene00049604 21ur-3013 No description available WB:WBGene00049605 21ur-449 No description available WB:WBGene00049606 21ur-2717 No description available WB:WBGene00049607 21ur-815 No description available WB:WBGene00049608 21ur-3236 No description available WB:WBGene00049609 21ur-1843 No description available WB:WBGene00049610 21ur-2496 No description available WB:WBGene00049611 21ur-1636 No description available WB:WBGene00049612 21ur-590 No description available WB:WBGene00049613 21ur-813 No description available WB:WBGene00049614 21ur-4376 No description available WB:WBGene00049615 21ur-1128 No description available WB:WBGene00049616 21ur-2008 No description available WB:WBGene00049617 21ur-1814 No description available WB:WBGene00049618 21ur-4704 No description available WB:WBGene00049619 21ur-4896 No description available WB:WBGene00049620 21ur-1059 No description available WB:WBGene00049621 21ur-2077 No description available WB:WBGene00049622 21ur-3466 No description available WB:WBGene00049623 21ur-1719 No description available WB:WBGene00049624 21ur-3156 No description available WB:WBGene00049625 21ur-82 No description available WB:WBGene00049626 21ur-4156 No description available WB:WBGene00049627 21ur-3527 No description available WB:WBGene00049628 21ur-1015 Enriched in neurons based on RNA-seq studies. WB:WBGene00049629 21ur-4992 No description available WB:WBGene00049630 21ur-5320 No description available WB:WBGene00049631 21ur-5091 No description available WB:WBGene00049632 21ur-4844 No description available WB:WBGene00049633 21ur-2732 Enriched in neurons based on RNA-seq studies. WB:WBGene00049634 21ur-2070 No description available WB:WBGene00049635 21ur-4205 No description available WB:WBGene00049636 21ur-3141 No description available WB:WBGene00049637 21ur-3967 No description available WB:WBGene00049638 21ur-4676 No description available WB:WBGene00049639 21ur-5056 No description available WB:WBGene00049640 21ur-1166 No description available WB:WBGene00049641 21ur-1213 No description available WB:WBGene00049642 21ur-2626 No description available WB:WBGene00049643 21ur-1356 No description available WB:WBGene00049644 21ur-2864 No description available WB:WBGene00049645 21ur-4148 No description available WB:WBGene00049646 21ur-3718 No description available WB:WBGene00049647 21ur-180 No description available WB:WBGene00049648 21ur-5318 No description available WB:WBGene00049649 21ur-3849 No description available WB:WBGene00049650 21ur-1735 No description available WB:WBGene00049651 21ur-242 No description available WB:WBGene00049652 21ur-4141 No description available WB:WBGene00049653 21ur-84 No description available WB:WBGene00049654 21ur-2604 No description available WB:WBGene00049655 21ur-1381 No description available WB:WBGene00049656 21ur-2668 No description available WB:WBGene00049657 21ur-1866 No description available WB:WBGene00049658 21ur-789 No description available WB:WBGene00049659 21ur-2237 No description available WB:WBGene00049660 21ur-1896 No description available WB:WBGene00049661 21ur-3894 No description available WB:WBGene00049662 21ur-795 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00049663 21ur-5272 No description available WB:WBGene00049664 21ur-740 No description available WB:WBGene00049665 21ur-1415 No description available WB:WBGene00049666 21ur-2456 No description available WB:WBGene00049667 21ur-424 No description available WB:WBGene00049668 21ur-1031 No description available WB:WBGene00049669 21ur-957 No description available WB:WBGene00049670 21ur-278 No description available WB:WBGene00049671 21ur-3890 No description available WB:WBGene00049672 21ur-3801 No description available WB:WBGene00049673 21ur-3680 No description available WB:WBGene00049674 21ur-5408 No description available WB:WBGene00049675 21ur-4889 No description available WB:WBGene00049676 21ur-3339 No description available WB:WBGene00049677 21ur-2551 No description available WB:WBGene00049678 21ur-1561 No description available WB:WBGene00049679 21ur-5415 No description available WB:WBGene00049680 21ur-863 No description available WB:WBGene00049681 21ur-3870 No description available WB:WBGene00049682 21ur-263 No description available WB:WBGene00049683 21ur-233 No description available WB:WBGene00049684 21ur-395 No description available WB:WBGene00049685 21ur-2190 No description available WB:WBGene00049686 21ur-4075 No description available WB:WBGene00049687 21ur-5126 No description available WB:WBGene00049688 21ur-1593 No description available WB:WBGene00049689 21ur-2269 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00049690 21ur-5330 No description available WB:WBGene00049691 21ur-2753 Enriched in neurons based on RNA-seq studies. WB:WBGene00049692 21ur-2887 No description available WB:WBGene00049693 21ur-4459 No description available WB:WBGene00049694 21ur-1247 No description available WB:WBGene00049695 21ur-30 No description available WB:WBGene00049696 21ur-882 No description available WB:WBGene00049697 21ur-2384 Enriched in neurons based on RNA-seq studies. WB:WBGene00049698 21ur-2074 No description available WB:WBGene00049699 21ur-3221 No description available WB:WBGene00049700 21ur-3877 No description available WB:WBGene00049701 21ur-2317 No description available WB:WBGene00049702 21ur-2630 No description available WB:WBGene00049703 21ur-4665 No description available WB:WBGene00049704 21ur-3867 No description available WB:WBGene00049705 21ur-2858 No description available WB:WBGene00049706 21ur-2475 No description available WB:WBGene00049707 21ur-1744 No description available WB:WBGene00049708 21ur-2313 No description available WB:WBGene00049709 21ur-4271 No description available WB:WBGene00049710 21ur-223 No description available WB:WBGene00049711 21ur-4293 No description available WB:WBGene00049712 21ur-3506 Enriched in neurons based on RNA-seq studies. WB:WBGene00049713 21ur-4544 No description available WB:WBGene00049714 21ur-981 No description available WB:WBGene00049715 21ur-56 No description available WB:WBGene00049716 21ur-747 No description available WB:WBGene00049717 21ur-5416 No description available WB:WBGene00049718 21ur-2036 No description available WB:WBGene00049719 21ur-2222 No description available WB:WBGene00049720 21ur-2529 No description available WB:WBGene00049721 21ur-5379 No description available WB:WBGene00049722 21ur-2848 No description available WB:WBGene00049723 21ur-3421 No description available WB:WBGene00049724 21ur-2204 No description available WB:WBGene00049725 21ur-1862 No description available WB:WBGene00049726 21ur-3046 No description available WB:WBGene00049727 21ur-4713 No description available WB:WBGene00049728 21ur-1955 No description available WB:WBGene00049729 21ur-2485 No description available WB:WBGene00049730 21ur-4431 No description available WB:WBGene00049731 21ur-3547 No description available WB:WBGene00049732 21ur-547 No description available WB:WBGene00049733 21ur-970 No description available WB:WBGene00049734 21ur-1946 No description available WB:WBGene00049735 21ur-4223 No description available WB:WBGene00049736 21ur-2535 No description available WB:WBGene00049737 21ur-2709 No description available WB:WBGene00049738 21ur-4107 No description available WB:WBGene00049739 21ur-4448 No description available WB:WBGene00049740 21ur-1792 Enriched in neurons based on RNA-seq studies. WB:WBGene00049741 21ur-2673 Enriched in neurons based on RNA-seq studies. WB:WBGene00049742 21ur-2943 No description available WB:WBGene00049743 21ur-4246 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00049744 21ur-5370 No description available WB:WBGene00049745 21ur-1007 No description available WB:WBGene00049746 21ur-4311 No description available WB:WBGene00049747 21ur-1794 No description available WB:WBGene00049748 21ur-943 No description available WB:WBGene00049749 21ur-2320 No description available WB:WBGene00049750 21ur-1583 No description available WB:WBGene00049751 21ur-3213 No description available WB:WBGene00049752 21ur-2227 No description available WB:WBGene00049753 21ur-535 No description available WB:WBGene00049754 21ur-932 No description available WB:WBGene00049755 21ur-1960 No description available WB:WBGene00049756 21ur-4104 No description available WB:WBGene00049757 21ur-2642 No description available WB:WBGene00049758 21ur-3751 No description available WB:WBGene00049759 21ur-1672 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00049760 21ur-3366 No description available WB:WBGene00049761 21ur-2197 No description available WB:WBGene00049762 21ur-1295 No description available WB:WBGene00049763 21ur-2500 No description available WB:WBGene00049764 21ur-4328 No description available WB:WBGene00049765 21ur-4346 Is affected by hpl-2 and rnp-6 based on RNA-seq studies. WB:WBGene00049766 21ur-3596 No description available WB:WBGene00049767 21ur-2510 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00049768 21ur-1952 No description available WB:WBGene00049769 21ur-3315 No description available WB:WBGene00049770 21ur-1429 No description available WB:WBGene00049771 21ur-2659 No description available WB:WBGene00049772 21ur-2026 No description available WB:WBGene00049773 21ur-691 No description available WB:WBGene00049774 21ur-4747 No description available WB:WBGene00049775 21ur-2520 No description available WB:WBGene00049776 21ur-1725 No description available WB:WBGene00049777 21ur-2654 No description available WB:WBGene00049778 21ur-841 No description available WB:WBGene00049779 21ur-4282 No description available WB:WBGene00049780 21ur-3352 No description available WB:WBGene00049781 21ur-1115 No description available WB:WBGene00049782 21ur-2108 No description available WB:WBGene00049783 21ur-4035 No description available WB:WBGene00049784 21ur-2069 No description available WB:WBGene00049785 21ur-3709 No description available WB:WBGene00049786 21ur-4879 No description available WB:WBGene00049787 21ur-2134 No description available WB:WBGene00049788 21ur-842 No description available WB:WBGene00049789 21ur-2761 No description available WB:WBGene00049790 21ur-1856 No description available WB:WBGene00049791 21ur-2375 No description available WB:WBGene00049792 21ur-4402 No description available WB:WBGene00049793 21ur-1052 No description available WB:WBGene00049794 21ur-431 No description available WB:WBGene00049795 21ur-4188 No description available WB:WBGene00049796 21ur-323 No description available WB:WBGene00049797 21ur-3092 No description available WB:WBGene00049798 21ur-3625 No description available WB:WBGene00049799 21ur-4357 No description available WB:WBGene00049800 21ur-4425 Enriched in neurons based on RNA-seq studies. WB:WBGene00049801 21ur-4066 No description available WB:WBGene00049802 21ur-211 No description available WB:WBGene00049803 21ur-2046 No description available WB:WBGene00049804 21ur-2112 No description available WB:WBGene00049805 21ur-2817 No description available WB:WBGene00049806 21ur-1069 No description available WB:WBGene00049807 21ur-3255 No description available WB:WBGene00049808 21ur-1641 No description available WB:WBGene00049809 21ur-4634 No description available WB:WBGene00049810 21ur-3415 No description available WB:WBGene00049811 21ur-2335 No description available WB:WBGene00049812 21ur-1379 No description available WB:WBGene00049813 21ur-2778 No description available WB:WBGene00049814 21ur-461 No description available WB:WBGene00049815 21ur-1393 No description available WB:WBGene00049816 21ur-1989 No description available WB:WBGene00049817 21ur-3031 No description available WB:WBGene00049818 21ur-466 No description available WB:WBGene00049819 21ur-4165 No description available WB:WBGene00049820 21ur-185 No description available WB:WBGene00049821 21ur-4596 No description available WB:WBGene00049822 21ur-1197 No description available WB:WBGene00049823 21ur-4012 No description available WB:WBGene00049824 21ur-1969 No description available WB:WBGene00049825 21ur-1827 No description available WB:WBGene00049826 21ur-3018 No description available WB:WBGene00049827 21ur-1387 No description available WB:WBGene00049828 21ur-512 No description available WB:WBGene00049829 21ur-1787 No description available WB:WBGene00049830 21ur-1648 No description available WB:WBGene00049831 21ur-3787 No description available WB:WBGene00049832 21ur-493 No description available WB:WBGene00049833 21ur-1851 No description available WB:WBGene00049834 21ur-1941 No description available WB:WBGene00049835 21ur-1928 No description available WB:WBGene00049836 21ur-37 No description available WB:WBGene00049837 21ur-417 No description available WB:WBGene00049838 21ur-1828 No description available WB:WBGene00049839 21ur-2792 Enriched in neurons based on RNA-seq studies. WB:WBGene00049840 21ur-3748 No description available WB:WBGene00049841 21ur-272 No description available WB:WBGene00049842 21ur-4360 No description available WB:WBGene00049843 21ur-1532 No description available WB:WBGene00049844 21ur-3334 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00049845 21ur-2596 No description available WB:WBGene00049846 21ur-640 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00049847 21ur-1830 No description available WB:WBGene00049848 21ur-2836 Enriched in AFD based on RNA-seq studies. Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00049849 21ur-3745 No description available WB:WBGene00049850 21ur-2083 No description available WB:WBGene00049851 21ur-1848 No description available WB:WBGene00049852 21ur-2804 No description available WB:WBGene00049853 21ur-657 No description available WB:WBGene00049854 21ur-5137 No description available WB:WBGene00049855 21ur-251 No description available WB:WBGene00049856 21ur-5200 No description available WB:WBGene00049857 21ur-3555 No description available WB:WBGene00049858 21ur-1200 No description available WB:WBGene00049859 21ur-4115 No description available WB:WBGene00049860 21ur-5226 No description available WB:WBGene00049861 21ur-2469 No description available WB:WBGene00049862 21ur-402 No description available WB:WBGene00049863 21ur-3125 Enriched in neurons based on RNA-seq studies. WB:WBGene00049864 21ur-4128 No description available WB:WBGene00049865 21ur-46 No description available WB:WBGene00049866 21ur-1250 No description available WB:WBGene00049867 21ur-4058 No description available WB:WBGene00049868 21ur-1339 No description available WB:WBGene00049869 21ur-2706 No description available WB:WBGene00049870 21ur-3480 No description available WB:WBGene00049871 21ur-3949 No description available WB:WBGene00049872 21ur-3542 No description available WB:WBGene00049873 21ur-4972 No description available WB:WBGene00049874 21ur-3851 No description available WB:WBGene00049875 21ur-1888 No description available WB:WBGene00049876 21ur-791 No description available WB:WBGene00049877 21ur-4287 No description available WB:WBGene00049878 21ur-3207 Enriched in neurons based on RNA-seq studies. WB:WBGene00049879 21ur-3563 No description available WB:WBGene00049880 21ur-4087 No description available WB:WBGene00049881 21ur-1440 No description available WB:WBGene00049882 21ur-3160 No description available WB:WBGene00049883 21ur-4555 No description available WB:WBGene00049884 21ur-5369 No description available WB:WBGene00049885 21ur-1196 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00049886 21ur-3165 No description available WB:WBGene00049887 21ur-4611 No description available WB:WBGene00049888 21ur-1334 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00049889 21ur-1140 No description available WB:WBGene00049890 21ur-4983 Enriched in neurons based on RNA-seq studies. WB:WBGene00049891 21ur-4194 No description available WB:WBGene00049892 21ur-2947 No description available WB:WBGene00049893 21ur-3259 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00049894 21ur-4755 No description available WB:WBGene00049895 21ur-5425 No description available WB:WBGene00049896 21ur-3631 No description available WB:WBGene00049897 21ur-2434 No description available WB:WBGene00049898 21ur-4187 Is affected by eat-2 based on microarray studies. WB:WBGene00049899 21ur-4573 No description available WB:WBGene00049900 21ur-3660 No description available WB:WBGene00049901 21ur-4995 No description available WB:WBGene00049902 21ur-555 No description available WB:WBGene00049903 21ur-4499 No description available WB:WBGene00049904 21ur-1586 No description available WB:WBGene00049905 21ur-736 No description available WB:WBGene00049906 21ur-1272 No description available WB:WBGene00049907 21ur-3840 No description available WB:WBGene00049908 21ur-1394 No description available WB:WBGene00049909 21ur-1143 No description available WB:WBGene00049910 21ur-4830 No description available WB:WBGene00049911 21ur-4837 No description available WB:WBGene00049912 21ur-3345 No description available WB:WBGene00049913 21ur-3864 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00049914 21ur-3824 Is affected by olrn-1 based on RNA-seq studies. WB:WBGene00049915 21ur-1804 Enriched in neurons based on RNA-seq studies. WB:WBGene00049916 21ur-1480 No description available WB:WBGene00049917 21ur-2068 No description available WB:WBGene00049918 21ur-3900 No description available WB:WBGene00049919 21ur-494 No description available WB:WBGene00049920 21ur-712 No description available WB:WBGene00049921 21ur-706 No description available WB:WBGene00049922 21ur-4841 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00049923 21ur-2477 No description available WB:WBGene00049924 21ur-239 No description available WB:WBGene00049925 21ur-4767 No description available WB:WBGene00049926 21ur-4364 No description available WB:WBGene00049927 21ur-1552 No description available WB:WBGene00049928 21ur-2835 No description available WB:WBGene00049929 21ur-249 No description available WB:WBGene00049930 21ur-2973 No description available WB:WBGene00049931 21ur-2723 No description available WB:WBGene00049932 21ur-3799 No description available WB:WBGene00049933 21ur-3644 No description available WB:WBGene00049934 21ur-354 No description available WB:WBGene00049935 21ur-2094 No description available WB:WBGene00049936 21ur-5359 No description available WB:WBGene00049937 21ur-3597 No description available WB:WBGene00049938 21ur-3004 No description available WB:WBGene00049939 21ur-5100 No description available WB:WBGene00049940 21ur-2575 No description available WB:WBGene00049941 21ur-437 No description available WB:WBGene00049942 21ur-1095 No description available WB:WBGene00049943 21ur-4626 No description available WB:WBGene00049944 21ur-1458 No description available WB:WBGene00049945 21ur-1296 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00049946 21ur-4855 No description available WB:WBGene00049947 21ur-5406 No description available WB:WBGene00049948 21ur-4791 No description available WB:WBGene00049949 21ur-879 No description available WB:WBGene00049950 21ur-5170 No description available WB:WBGene00049951 21ur-2769 No description available WB:WBGene00049952 21ur-4006 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00049953 21ur-110 No description available WB:WBGene00049954 21ur-321 Enriched in neurons based on RNA-seq studies. WB:WBGene00049955 21ur-5145 No description available WB:WBGene00049956 21ur-1574 No description available WB:WBGene00049957 21ur-2674 No description available WB:WBGene00049958 21ur-4655 No description available WB:WBGene00049959 21ur-4946 No description available WB:WBGene00049960 21ur-3931 No description available WB:WBGene00049961 21ur-5368 No description available WB:WBGene00049962 21ur-4556 No description available WB:WBGene00049963 21ur-5128 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00049964 21ur-2412 No description available WB:WBGene00049965 21ur-1373 No description available WB:WBGene00049966 21ur-5251 No description available WB:WBGene00049967 21ur-5041 No description available WB:WBGene00049968 21ur-2869 No description available WB:WBGene00049969 21ur-430 No description available WB:WBGene00049970 21ur-2852 No description available WB:WBGene00049971 21ur-2585 No description available WB:WBGene00049972 21ur-1548 No description available WB:WBGene00049973 21ur-5123 No description available WB:WBGene00049974 21ur-1428 No description available WB:WBGene00049975 21ur-1500 No description available WB:WBGene00049976 21ur-1531 No description available WB:WBGene00049977 21ur-651 No description available WB:WBGene00049978 21ur-2398 No description available WB:WBGene00049979 21ur-3603 No description available WB:WBGene00049980 21ur-3268 No description available WB:WBGene00049981 21ur-1035 No description available WB:WBGene00049982 21ur-1861 No description available WB:WBGene00049983 21ur-1759 No description available WB:WBGene00049984 21ur-4245 No description available WB:WBGene00049985 21ur-2924 No description available WB:WBGene00049986 21ur-1149 No description available WB:WBGene00049987 21ur-4403 No description available WB:WBGene00049988 21ur-4505 No description available WB:WBGene00049989 21ur-2963 No description available WB:WBGene00049990 21ur-3083 No description available WB:WBGene00049991 21ur-3589 Is affected by eat-2 based on microarray studies. WB:WBGene00049992 21ur-4668 No description available WB:WBGene00049993 21ur-4394 No description available WB:WBGene00049994 21ur-4865 No description available WB:WBGene00049995 21ur-4770 No description available WB:WBGene00049996 21ur-166 No description available WB:WBGene00049997 21ur-2641 No description available WB:WBGene00049998 21ur-568 No description available WB:WBGene00049999 21ur-1883 No description available WB:WBGene00050000 21ur-548 No description available WB:WBGene00050001 21ur-64 No description available WB:WBGene00050002 21ur-5118 No description available WB:WBGene00050003 21ur-2810 No description available WB:WBGene00050004 21ur-3696 No description available WB:WBGene00050005 21ur-1914 No description available WB:WBGene00050006 21ur-3099 No description available WB:WBGene00050007 21ur-4462 No description available WB:WBGene00050008 21ur-5255 No description available WB:WBGene00050009 21ur-5140 No description available WB:WBGene00050010 21ur-1454 No description available WB:WBGene00050011 21ur-4023 No description available WB:WBGene00050012 21ur-2031 No description available WB:WBGene00050013 21ur-3618 No description available WB:WBGene00050014 21ur-904 No description available WB:WBGene00050015 21ur-3077 No description available WB:WBGene00050016 21ur-4687 No description available WB:WBGene00050017 21ur-2507 No description available WB:WBGene00050018 21ur-2582 No description available WB:WBGene00050019 21ur-612 No description available WB:WBGene00050020 21ur-4418 No description available WB:WBGene00050021 21ur-3135 No description available WB:WBGene00050022 21ur-5099 Enriched in neurons based on RNA-seq studies. WB:WBGene00050023 21ur-5003 No description available WB:WBGene00050024 21ur-1453 No description available WB:WBGene00050025 21ur-1728 No description available WB:WBGene00050026 21ur-2052 No description available WB:WBGene00050027 21ur-3837 No description available WB:WBGene00050028 21ur-3180 No description available WB:WBGene00050029 21ur-385 No description available WB:WBGene00050030 21ur-441 No description available WB:WBGene00050031 21ur-2615 No description available WB:WBGene00050032 21ur-4921 No description available WB:WBGene00050033 21ur-3498 No description available WB:WBGene00050034 21ur-3915 No description available WB:WBGene00050035 21ur-3802 No description available WB:WBGene00050036 21ur-1734 No description available WB:WBGene00050037 21ur-2011 No description available WB:WBGene00050038 21ur-2571 No description available WB:WBGene00050039 21ur-685 No description available WB:WBGene00050040 21ur-5149 No description available WB:WBGene00050041 21ur-5077 No description available WB:WBGene00050042 21ur-929 No description available WB:WBGene00050043 21ur-2400 No description available WB:WBGene00050044 21ur-1073 No description available WB:WBGene00050045 21ur-3692 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00050046 21ur-1323 No description available WB:WBGene00050047 21ur-3534 No description available WB:WBGene00050048 21ur-1933 No description available WB:WBGene00050049 21ur-626 No description available WB:WBGene00050050 21ur-3277 No description available WB:WBGene00050051 21ur-1875 No description available WB:WBGene00050052 21ur-4940 No description available WB:WBGene00050053 21ur-4219 No description available WB:WBGene00050054 21ur-5442 No description available WB:WBGene00050055 21ur-4937 No description available WB:WBGene00050056 21ur-3436 No description available WB:WBGene00050057 21ur-669 No description available WB:WBGene00050058 21ur-3308 No description available WB:WBGene00050059 21ur-5221 No description available WB:WBGene00050060 21ur-1022 No description available WB:WBGene00050061 21ur-5015 No description available WB:WBGene00050062 21ur-1988 No description available WB:WBGene00050063 21ur-3623 No description available WB:WBGene00050064 21ur-3811 No description available WB:WBGene00050065 21ur-5373 No description available WB:WBGene00050066 21ur-3235 No description available WB:WBGene00050067 21ur-2474 No description available WB:WBGene00050068 21ur-3178 No description available WB:WBGene00050069 21ur-3451 No description available WB:WBGene00050070 21ur-2191 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00050071 21ur-3179 No description available WB:WBGene00050072 21ur-1493 No description available WB:WBGene00050073 21ur-1305 No description available WB:WBGene00050074 21ur-1051 No description available WB:WBGene00050075 21ur-688 No description available WB:WBGene00050076 21ur-756 Is affected by daf-2 based on microarray studies. WB:WBGene00050077 21ur-1405 No description available WB:WBGene00050078 21ur-4811 No description available WB:WBGene00050079 21ur-3438 No description available WB:WBGene00050080 21ur-1083 No description available WB:WBGene00050081 21ur-2324 No description available WB:WBGene00050082 21ur-3985 No description available WB:WBGene00050083 21ur-2681 No description available WB:WBGene00050084 21ur-3007 No description available WB:WBGene00050085 21ur-2383 No description available WB:WBGene00050086 21ur-4932 No description available WB:WBGene00050087 21ur-788 No description available WB:WBGene00050088 21ur-1155 No description available WB:WBGene00050089 21ur-798 No description available WB:WBGene00050090 21ur-3562 No description available WB:WBGene00050091 21ur-2952 No description available WB:WBGene00050092 21ur-1567 No description available WB:WBGene00050093 21ur-896 No description available WB:WBGene00050094 21ur-1847 No description available WB:WBGene00050095 21ur-5409 No description available WB:WBGene00050096 21ur-2025 No description available WB:WBGene00050097 21ur-5246 No description available WB:WBGene00050098 21ur-2209 No description available WB:WBGene00050099 21ur-3428 No description available WB:WBGene00050100 21ur-4532 No description available WB:WBGene00050101 21ur-1315 No description available WB:WBGene00050102 21ur-1763 No description available WB:WBGene00050103 21ur-4733 No description available WB:WBGene00050104 21ur-264 No description available WB:WBGene00050105 21ur-2137 Is affected by Tamoxifen based on RNA-seq studies. WB:WBGene00050106 21ur-1909 No description available WB:WBGene00050107 21ur-627 No description available WB:WBGene00050108 21ur-15 No description available WB:WBGene00050109 21ur-2219 No description available WB:WBGene00050110 21ur-4517 No description available WB:WBGene00050111 21ur-2981 No description available WB:WBGene00050112 21ur-71 No description available WB:WBGene00050113 21ur-4798 No description available WB:WBGene00050114 21ur-3264 No description available WB:WBGene00050115 21ur-1745 No description available WB:WBGene00050116 21ur-674 No description available WB:WBGene00050117 21ur-781 Enriched in neurons based on RNA-seq studies. WB:WBGene00050118 21ur-1623 No description available WB:WBGene00050119 21ur-1577 No description available WB:WBGene00050120 21ur-5024 No description available WB:WBGene00050121 21ur-3503 No description available WB:WBGene00050122 21ur-2155 No description available WB:WBGene00050123 21ur-3460 No description available WB:WBGene00050124 21ur-1208 No description available WB:WBGene00050125 21ur-4923 No description available WB:WBGene00050126 21ur-4543 No description available WB:WBGene00050127 21ur-3920 No description available WB:WBGene00050128 21ur-3486 No description available WB:WBGene00050129 21ur-3149 No description available WB:WBGene00050130 21ur-779 No description available WB:WBGene00050131 21ur-2905 No description available WB:WBGene00050132 21ur-148 No description available WB:WBGene00050133 21ur-2544 No description available WB:WBGene00050134 21ur-5033 No description available WB:WBGene00050135 21ur-1179 No description available WB:WBGene00050136 21ur-3117 No description available WB:WBGene00050137 21ur-859 No description available WB:WBGene00050138 21ur-4570 No description available WB:WBGene00050139 21ur-5391 No description available WB:WBGene00050140 21ur-2144 No description available WB:WBGene00050141 21ur-4884 No description available WB:WBGene00050142 21ur-2760 No description available WB:WBGene00050143 21ur-507 No description available WB:WBGene00050144 21ur-1288 No description available WB:WBGene00050145 21ur-4600 No description available WB:WBGene00050146 21ur-4961 No description available WB:WBGene00050147 21ur-4237 No description available WB:WBGene00050148 21ur-5321 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00050149 21ur-451 No description available WB:WBGene00050150 21ur-1519 No description available WB:WBGene00050151 21ur-5347 No description available WB:WBGene00050152 21ur-1560 No description available WB:WBGene00050153 21ur-1526 No description available WB:WBGene00050154 21ur-5387 No description available WB:WBGene00050155 21ur-2393 No description available WB:WBGene00050156 21ur-5168 No description available WB:WBGene00050157 21ur-4565 No description available WB:WBGene00050158 21ur-2823 No description available WB:WBGene00050159 21ur-1026 No description available WB:WBGene00050160 21ur-3659 No description available WB:WBGene00050161 21ur-1509 No description available WB:WBGene00050162 21ur-776 No description available WB:WBGene00050163 21ur-3193 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00050164 21ur-2988 No description available WB:WBGene00050165 21ur-1708 No description available WB:WBGene00050166 21ur-3078 Is affected by eat-2 based on microarray studies. WB:WBGene00050167 21ur-4718 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00050168 21ur-4411 No description available WB:WBGene00050169 21ur-2277 Enriched in neurons based on RNA-seq studies. WB:WBGene00050170 21ur-4691 No description available WB:WBGene00050171 21ur-5157 No description available WB:WBGene00050172 21ur-1105 No description available WB:WBGene00050173 21ur-5310 No description available WB:WBGene00050174 21ur-2300 No description available WB:WBGene00050175 21ur-2283 No description available WB:WBGene00050176 21ur-1240 No description available WB:WBGene00050177 21ur-5241 No description available WB:WBGene00050178 21ur-5437 No description available WB:WBGene00050179 21ur-1819 No description available WB:WBGene00050180 21ur-2881 No description available WB:WBGene00050181 21ur-4176 No description available WB:WBGene00050182 21ur-347 No description available WB:WBGene00050183 21ur-5092 No description available WB:WBGene00050184 21ur-1653 No description available WB:WBGene00050185 21ur-2491 Is affected by eat-2 based on microarray studies. WB:WBGene00050186 21ur-5083 No description available WB:WBGene00050187 21ur-874 No description available WB:WBGene00050188 21ur-5067 No description available WB:WBGene00050189 21ur-3333 No description available WB:WBGene00050190 21ur-832 No description available WB:WBGene00050191 21ur-5031 No description available WB:WBGene00050192 21ur-4196 No description available WB:WBGene00050193 21ur-4046 No description available WB:WBGene00050194 21ur-2177 No description available WB:WBGene00050195 21ur-633 No description available WB:WBGene00050196 21ur-3142 No description available WB:WBGene00050197 21ur-39 No description available WB:WBGene00050198 21ur-2486 No description available WB:WBGene00050199 21ur-4782 No description available WB:WBGene00050200 21ur-3798 No description available WB:WBGene00050201 21ur-5199 No description available WB:WBGene00050202 21ur-3895 No description available WB:WBGene00050203 21ur-3564 No description available WB:WBGene00050204 21ur-277 No description available WB:WBGene00050205 21ur-3998 No description available WB:WBGene00050206 21ur-4618 No description available WB:WBGene00050207 21ur-4582 No description available WB:WBGene00050208 21ur-5319 No description available WB:WBGene00050209 21ur-4171 No description available WB:WBGene00050210 21ur-2232 No description available WB:WBGene00050211 21ur-2845 No description available WB:WBGene00050212 21ur-849 No description available WB:WBGene00050213 21ur-2015 No description available WB:WBGene00050214 21ur-5249 No description available WB:WBGene00050215 21ur-2528 No description available WB:WBGene00050216 21ur-5376 No description available WB:WBGene00050217 21ur-4076 No description available WB:WBGene00050218 21ur-1891 No description available WB:WBGene00050219 21ur-2234 No description available WB:WBGene00050220 21ur-2385 No description available WB:WBGene00050221 21ur-2632 Enriched in neurons based on RNA-seq studies. WB:WBGene00050222 21ur-4489 No description available WB:WBGene00050223 21ur-1533 No description available WB:WBGene00050224 21ur-3093 No description available WB:WBGene00050225 21ur-3717 Enriched in neurons based on RNA-seq studies. WB:WBGene00050226 21ur-2314 No description available WB:WBGene00050227 21ur-910 No description available WB:WBGene00050228 21ur-1214 No description available WB:WBGene00050229 21ur-4545 No description available WB:WBGene00050230 21ur-399 No description available WB:WBGene00050231 21ur-2550 No description available WB:WBGene00050232 21ur-3474 No description available WB:WBGene00050233 21ur-5305 No description available WB:WBGene00050234 21ur-2009 No description available WB:WBGene00050235 21ur-4386 No description available WB:WBGene00050236 21ur-3079 No description available WB:WBGene00050237 21ur-4604 No description available WB:WBGene00050238 21ur-425 No description available WB:WBGene00050239 21ur-3413 No description available WB:WBGene00050240 21ur-1630 No description available WB:WBGene00050241 21ur-2287 No description available WB:WBGene00050242 21ur-1654 No description available WB:WBGene00050243 21ur-5070 No description available WB:WBGene00050244 21ur-105 No description available WB:WBGene00050245 21ur-1592 No description available WB:WBGene00050246 21ur-1491 No description available WB:WBGene00050247 21ur-2027 No description available WB:WBGene00050248 21ur-2075 No description available WB:WBGene00050249 21ur-4899 No description available WB:WBGene00050250 21ur-5245 Enriched in neurons based on RNA-seq studies. WB:WBGene00050251 21ur-2323 No description available WB:WBGene00050252 21ur-796 No description available WB:WBGene00050253 21ur-2631 No description available WB:WBGene00050254 21ur-2854 No description available WB:WBGene00050255 21ur-2196 No description available WB:WBGene00050256 21ur-2953 Enriched in neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00050257 21ur-2268 No description available WB:WBGene00050258 21ur-2675 No description available WB:WBGene00050259 21ur-316 No description available WB:WBGene00050260 21ur-394 No description available WB:WBGene00050261 21ur-5371 No description available WB:WBGene00050262 21ur-3876 No description available WB:WBGene00050263 21ur-4666 No description available WB:WBGene00050264 21ur-862 No description available WB:WBGene00050265 21ur-3222 No description available WB:WBGene00050266 21ur-2443 No description available WB:WBGene00050267 21ur-3889 No description available WB:WBGene00050268 21ur-4272 No description available WB:WBGene00050269 21ur-2318 No description available WB:WBGene00050270 21ur-2221 No description available WB:WBGene00050271 21ur-2705 No description available WB:WBGene00050272 21ur-3403 No description available WB:WBGene00050273 21ur-3872 No description available WB:WBGene00050274 21ur-3047 No description available WB:WBGene00050275 21ur-308 No description available WB:WBGene00050276 21ur-5331 No description available WB:WBGene00050277 21ur-1743 No description available WB:WBGene00050278 21ur-746 No description available WB:WBGene00050279 21ur-1978 No description available WB:WBGene00050280 21ur-4047 No description available WB:WBGene00050281 21ur-206 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00050282 21ur-3378 No description available WB:WBGene00050283 21ur-1698 No description available WB:WBGene00050284 21ur-997 No description available WB:WBGene00050285 21ur-1966 No description available WB:WBGene00050286 21ur-3881 No description available WB:WBGene00050287 21ur-2748 No description available WB:WBGene00050288 21ur-3966 No description available WB:WBGene00050289 21ur-3640 No description available WB:WBGene00050290 21ur-2665 No description available WB:WBGene00050291 21ur-2532 No description available WB:WBGene00050292 21ur-556 No description available WB:WBGene00050293 21ur-1023 Enriched in neurons based on RNA-seq studies. WB:WBGene00050294 21ur-4279 No description available WB:WBGene00050295 21ur-2408 No description available WB:WBGene00050296 21ur-2351 No description available WB:WBGene00050297 21ur-4473 No description available WB:WBGene00050298 21ur-3102 No description available WB:WBGene00050299 21ur-3750 No description available WB:WBGene00050300 21ur-170 No description available WB:WBGene00050301 21ur-1277 No description available WB:WBGene00050302 21ur-3490 No description available WB:WBGene00050303 21ur-1002 No description available WB:WBGene00050304 21ur-4322 No description available WB:WBGene00050305 21ur-2307 No description available WB:WBGene00050306 21ur-1384 No description available WB:WBGene00050307 21ur-301 No description available WB:WBGene00050308 21ur-1889 No description available WB:WBGene00050309 21ur-2376 No description available WB:WBGene00050310 21ur-4904 No description available WB:WBGene00050311 21ur-4136 No description available WB:WBGene00050312 21ur-3622 No description available WB:WBGene00050313 21ur-4224 No description available WB:WBGene00050314 21ur-3482 No description available WB:WBGene00050315 21ur-3200 No description available WB:WBGene00050316 21ur-3886 No description available WB:WBGene00050317 21ur-4389 No description available WB:WBGene00050318 21ur-4135 No description available WB:WBGene00050319 21ur-4485 No description available WB:WBGene00050320 21ur-4850 Is affected by smn-1 based on RNA-seq studies. WB:WBGene00050321 21ur-4636 No description available WB:WBGene00050322 21ur-1820 No description available WB:WBGene00050323 21ur-1753 Is affected by daf-2 based on microarray studies. WB:WBGene00050324 21ur-4377 No description available WB:WBGene00050325 21ur-1710 No description available WB:WBGene00050326 21ur-4993 No description available WB:WBGene00050327 21ur-4231 No description available WB:WBGene00050328 21ur-3891 No description available WB:WBGene00050329 21ur-3862 No description available WB:WBGene00050330 21ur-5060 No description available WB:WBGene00050331 21ur-4050 No description available WB:WBGene00050332 21ur-812 No description available WB:WBGene00050333 21ur-1058 No description available WB:WBGene00050334 21ur-814 No description available WB:WBGene00050335 21ur-2763 No description available WB:WBGene00050336 21ur-4312 No description available WB:WBGene00050337 21ur-4675 No description available WB:WBGene00050338 21ur-4822 No description available WB:WBGene00050339 21ur-2605 No description available WB:WBGene00050340 21ur-3937 No description available WB:WBGene00050341 21ur-2299 No description available WB:WBGene00050342 21ur-1511 No description available WB:WBGene00050343 21ur-1478 No description available WB:WBGene00050344 21ur-4843 Enriched in neurons based on RNA-seq studies. WB:WBGene00050345 21ur-1938 No description available WB:WBGene00050346 21ur-1366 No description available WB:WBGene00050347 21ur-4204 No description available WB:WBGene00050348 21ur-4619 No description available WB:WBGene00050349 21ur-3024 Enriched in neurons based on RNA-seq studies. WB:WBGene00050350 21ur-2461 No description available WB:WBGene00050351 21ur-2071 No description available WB:WBGene00050352 21ur-2936 No description available WB:WBGene00050353 21ur-1773 No description available WB:WBGene00050354 21ur-2904 No description available WB:WBGene00050355 21ur-3974 No description available WB:WBGene00050356 21ur-192 No description available WB:WBGene00050357 21ur-1637 No description available WB:WBGene00050358 21ur-4098 No description available WB:WBGene00050359 21ur-711 No description available WB:WBGene00050360 21ur-7 Enriched in neurons based on RNA-seq studies. WB:WBGene00050361 21ur-2170 No description available WB:WBGene00050362 21ur-4761 No description available WB:WBGene00050363 21ur-1333 No description available WB:WBGene00050364 21ur-4730 No description available WB:WBGene00050365 21ur-4013 No description available WB:WBGene00050366 21ur-4166 No description available WB:WBGene00050367 21ur-4127 No description available WB:WBGene00050368 21ur-3852 No description available WB:WBGene00050369 21ur-5332 No description available WB:WBGene00050370 21ur-3522 No description available WB:WBGene00050371 21ur-4625 No description available WB:WBGene00050372 21ur-949 No description available WB:WBGene00050373 21ur-1826 No description available WB:WBGene00050374 21ur-3164 No description available WB:WBGene00050375 21ur-4361 No description available WB:WBGene00050376 21ur-3766 No description available WB:WBGene00050377 21ur-1353 No description available WB:WBGene00050378 21ur-460 No description available WB:WBGene00050379 21ur-1679 No description available WB:WBGene00050380 21ur-3669 No description available WB:WBGene00050381 21ur-1921 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00050382 21ur-1057 No description available WB:WBGene00050383 21ur-3930 No description available WB:WBGene00050384 21ur-3030 No description available WB:WBGene00050385 21ur-3684 No description available WB:WBGene00050386 21ur-1193 No description available WB:WBGene00050387 21ur-1414 No description available WB:WBGene00050388 21ur-36 No description available WB:WBGene00050389 21ur-5225 No description available WB:WBGene00050390 21ur-4907 No description available WB:WBGene00050391 21ur-1036 Enriched in neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00050392 21ur-2834 No description available WB:WBGene00050393 21ur-2082 No description available WB:WBGene00050394 21ur-3747 Is affected by daf-2 based on microarray studies. WB:WBGene00050395 21ur-74 No description available WB:WBGene00050396 21ur-1915 No description available WB:WBGene00050397 21ur-2124 Is affected by lem-2; emr-1; and etr-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00050398 21ur-4778 Enriched in neurons based on RNA-seq studies. WB:WBGene00050399 21ur-2364 No description available WB:WBGene00050400 21ur-104 No description available WB:WBGene00050401 21ur-3943 No description available WB:WBGene00050402 21ur-573 No description available WB:WBGene00050403 21ur-373 No description available WB:WBGene00050404 21ur-4829 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00050405 21ur-2107 No description available WB:WBGene00050406 21ur-4790 Enriched in neurons based on RNA-seq studies. WB:WBGene00050407 21ur-1669 No description available WB:WBGene00050408 21ur-4304 No description available WB:WBGene00050409 21ur-2305 Enriched in neurons based on RNA-seq studies. WB:WBGene00050410 21ur-4262 No description available WB:WBGene00050411 21ur-1668 Enriched in neurons based on RNA-seq studies. WB:WBGene00050412 21ur-3950 No description available WB:WBGene00050413 21ur-3770 No description available WB:WBGene00050414 21ur-1815 No description available WB:WBGene00050415 21ur-2439 No description available WB:WBGene00050416 21ur-658 No description available WB:WBGene00050417 21ur-4263 Enriched in neurons based on RNA-seq studies. Is affected by swsn-1 based on RNA-seq studies. WB:WBGene00050418 21ur-2597 No description available WB:WBGene00050419 21ur-4195 No description available WB:WBGene00050420 21ur-3649 No description available WB:WBGene00050421 21ur-4757 No description available WB:WBGene00050422 21ur-3541 No description available WB:WBGene00050423 21ur-4040 No description available WB:WBGene00050424 21ur-3901 No description available WB:WBGene00050425 21ur-4956 No description available WB:WBGene00050426 21ur-3948 No description available WB:WBGene00050427 21ur-2049 No description available WB:WBGene00050428 21ur-2497 No description available WB:WBGene00050429 21ur-1793 Enriched in neurons based on RNA-seq studies. WB:WBGene00050430 21ur-1060 No description available WB:WBGene00050431 21ur-528 No description available WB:WBGene00050432 21ur-4984 No description available WB:WBGene00050433 21ur-792 No description available WB:WBGene00050434 21ur-1389 No description available WB:WBGene00050435 21ur-536 No description available WB:WBGene00050436 21ur-1156 No description available WB:WBGene00050437 21ur-1880 No description available WB:WBGene00050438 21ur-4911 No description available WB:WBGene00050439 21ur-295 No description available WB:WBGene00050440 21ur-771 No description available WB:WBGene00050441 21ur-4112 No description available WB:WBGene00050442 21ur-3725 No description available WB:WBGene00050443 21ur-1940 No description available WB:WBGene00050444 21ur-4180 No description available WB:WBGene00050445 21ur-3307 No description available WB:WBGene00050446 21ur-513 No description available WB:WBGene00050447 21ur-4938 No description available WB:WBGene00050448 21ur-3192 No description available WB:WBGene00050449 21ur-4597 No description available WB:WBGene00050450 21ur-3161 No description available WB:WBGene00050451 21ur-4913 No description available WB:WBGene00050452 21ur-3299 No description available WB:WBGene00050453 21ur-2660 No description available WB:WBGene00050454 21ur-2693 No description available WB:WBGene00050455 21ur-1788 No description available WB:WBGene00050456 21ur-5114 Enriched in neurons based on RNA-seq studies. WB:WBGene00050457 21ur-2946 No description available WB:WBGene00050458 21ur-177 No description available WB:WBGene00050459 21ur-3186 No description available WB:WBGene00050460 21ur-4088 No description available WB:WBGene00050461 21ur-3019 No description available WB:WBGene00050462 21ur-5026 No description available WB:WBGene00050463 21ur-4159 No description available WB:WBGene00050464 21ur-92 No description available WB:WBGene00050465 21ur-3505 No description available WB:WBGene00050466 21ur-128 No description available WB:WBGene00050467 21ur-1671 No description available WB:WBGene00050468 21ur-1294 No description available WB:WBGene00050469 21ur-2653 No description available WB:WBGene00050470 21ur-3499 No description available WB:WBGene00050471 21ur-55 No description available WB:WBGene00050472 21ur-840 No description available WB:WBGene00050473 21ur-1949 No description available WB:WBGene00050474 21ur-4060 No description available WB:WBGene00050475 21ur-65 No description available WB:WBGene00050476 21ur-3214 No description available WB:WBGene00050477 21ur-1662 No description available WB:WBGene00050478 21ur-1399 Is affected by eat-2 based on microarray studies. WB:WBGene00050479 21ur-2377 No description available WB:WBGene00050480 21ur-3423 No description available WB:WBGene00050481 21ur-485 No description available WB:WBGene00050482 21ur-1863 No description available WB:WBGene00050483 21ur-931 No description available WB:WBGene00050484 21ur-3435 No description available WB:WBGene00050485 21ur-1582 No description available WB:WBGene00050486 21ur-944 No description available WB:WBGene00050487 21ur-247 No description available WB:WBGene00050488 21ur-1622 No description available WB:WBGene00050489 21ur-1185 Is affected by lem-2; emr-1; and set-2 based on RNA-seq studies. WB:WBGene00050490 21ur-4449 No description available WB:WBGene00050491 21ur-1006 No description available WB:WBGene00050492 21ur-4281 No description available WB:WBGene00050493 21ur-3365 No description available WB:WBGene00050494 21ur-1649 Is affected by lem-2; emr-1; and dpy-21 based on RNA-seq studies. WB:WBGene00050495 21ur-2518 No description available WB:WBGene00050496 21ur-1859 No description available WB:WBGene00050497 21ur-2002 No description available WB:WBGene00050498 21ur-5005 No description available WB:WBGene00050499 21ur-1961 No description available WB:WBGene00050500 21ur-1953 No description available WB:WBGene00050501 21ur-4807 No description available WB:WBGene00050502 21ur-720 No description available WB:WBGene00050503 21ur-1203 No description available WB:WBGene00050504 21ur-2739 No description available WB:WBGene00050505 21ur-383 No description available WB:WBGene00050506 21ur-3351 No description available WB:WBGene00050507 21ur-4640 No description available WB:WBGene00050508 21ur-3548 No description available WB:WBGene00050509 21ur-4656 No description available WB:WBGene00050510 21ur-4397 No description available WB:WBGene00050511 21ur-4438 No description available WB:WBGene00050512 21ur-5344 No description available WB:WBGene00050513 21ur-2104 No description available WB:WBGene00050514 21ur-472 No description available WB:WBGene00050515 21ur-2127 Enriched in neurons based on RNA-seq studies. WB:WBGene00050516 21ur-141 No description available WB:WBGene00050517 21ur-1850 No description available WB:WBGene00050518 21ur-4189 No description available WB:WBGene00050519 21ur-5297 No description available WB:WBGene00050520 21ur-3256 No description available WB:WBGene00050521 21ur-2897 No description available WB:WBGene00050522 21ur-3820 No description available WB:WBGene00050523 21ur-5047 No description available WB:WBGene00050524 21ur-2942 No description available WB:WBGene00050525 21ur-917 No description available WB:WBGene00050526 21ur-4025 No description available WB:WBGene00050527 21ur-2886 No description available WB:WBGene00050528 21ur-2244 No description available WB:WBGene00050529 21ur-1547 No description available WB:WBGene00050530 21ur-2243 No description available WB:WBGene00050531 21ur-1842 No description available WB:WBGene00050532 21ur-4642 Enriched in neurons based on RNA-seq studies. WB:WBGene00050533 21ur-3467 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00050534 21ur-3675 No description available WB:WBGene00050535 21ur-1558 No description available WB:WBGene00050536 21ur-1923 No description available WB:WBGene00050537 21ur-1068 No description available WB:WBGene00050538 21ur-2643 No description available WB:WBGene00050539 21ur-4818 No description available WB:WBGene00050540 21ur-3296 No description available WB:WBGene00050541 21ur-1900 No description available WB:WBGene00050542 21ur-5115 No description available WB:WBGene00050543 21ur-2508 No description available WB:WBGene00050544 21ur-2506 No description available WB:WBGene00050545 21ur-2063 No description available WB:WBGene00050546 21ur-243 No description available WB:WBGene00050547 21ur-4404 No description available WB:WBGene00050548 21ur-210 No description available WB:WBGene00050549 21ur-5256 No description available WB:WBGene00050550 21ur-150 Enriched in neurons based on RNA-seq studies. WB:WBGene00050551 21ur-3119 Enriched in neurons based on RNA-seq studies. WB:WBGene00050552 21ur-1791 No description available WB:WBGene00050553 21ur-1501 No description available WB:WBGene00050554 21ur-1527 No description available WB:WBGene00050555 21ur-2186 No description available WB:WBGene00050556 21ur-2583 No description available WB:WBGene00050557 21ur-984 No description available WB:WBGene00050558 21ur-319 No description available WB:WBGene00050559 21ur-5277 No description available WB:WBGene00050560 21ur-721 No description available WB:WBGene00050561 21ur-3267 No description available WB:WBGene00050562 21ur-4920 No description available WB:WBGene00050563 21ur-2962 No description available WB:WBGene00050564 21ur-3695 No description available WB:WBGene00050565 21ur-3813 No description available WB:WBGene00050566 21ur-4259 No description available WB:WBGene00050567 21ur-4354 No description available WB:WBGene00050568 21ur-1604 No description available WB:WBGene00050569 21ur-5124 No description available WB:WBGene00050570 21ur-4417 No description available WB:WBGene00050571 21ur-3588 No description available WB:WBGene00050572 21ur-3082 No description available WB:WBGene00050573 21ur-2784 Enriched in neurons based on RNA-seq studies. WB:WBGene00050574 21ur-3944 No description available WB:WBGene00050575 21ur-2267 No description available WB:WBGene00050576 21ur-2103 No description available WB:WBGene00050577 21ur-567 No description available WB:WBGene00050578 21ur-4806 No description available WB:WBGene00050579 21ur-5065 Is affected by ikb-1 based on RNA-seq studies. WB:WBGene00050580 21ur-4177 Enriched in neurons based on RNA-seq studies. WB:WBGene00050581 21ur-2150 No description available WB:WBGene00050582 21ur-1306 No description available WB:WBGene00050583 21ur-2925 No description available WB:WBGene00050584 21ur-3477 No description available WB:WBGene00050585 21ur-282 No description available WB:WBGene00050586 21ur-3407 No description available WB:WBGene00050587 21ur-3916 No description available WB:WBGene00050588 21ur-2511 Enriched in neurons based on RNA-seq studies. WB:WBGene00050589 21ur-473 No description available WB:WBGene00050590 21ur-5285 No description available WB:WBGene00050591 21ur-3803 No description available WB:WBGene00050592 21ur-132 No description available WB:WBGene00050593 21ur-374 No description available WB:WBGene00050594 21ur-1629 No description available WB:WBGene00050595 21ur-1727 No description available WB:WBGene00050596 21ur-4365 No description available WB:WBGene00050597 21ur-1148 No description available WB:WBGene00050598 21ur-1488 No description available WB:WBGene00050599 21ur-35 Enriched in neurons based on RNA-seq studies. WB:WBGene00050600 21ur-5222 No description available WB:WBGene00050601 21ur-806 No description available WB:WBGene00050602 21ur-3917 No description available WB:WBGene00050603 21ur-1222 No description available WB:WBGene00050604 21ur-5252 No description available WB:WBGene00050605 21ur-3420 No description available WB:WBGene00050606 21ur-363 No description available WB:WBGene00050607 21ur-903 No description available WB:WBGene00050608 21ur-258 No description available WB:WBGene00050609 21ur-3134 No description available WB:WBGene00050610 21ur-2726 No description available WB:WBGene00050611 21ur-2091 No description available WB:WBGene00050612 21ur-2570 Enriched in neurons based on RNA-seq studies. WB:WBGene00050613 21ur-1487 No description available WB:WBGene00050614 21ur-3676 No description available WB:WBGene00050615 21ur-5042 No description available WB:WBGene00050616 21ur-2164 No description available WB:WBGene00050617 21ur-2242 No description available WB:WBGene00050618 21ur-4783 No description available WB:WBGene00050619 21ur-3529 No description available WB:WBGene00050620 21ur-4056 No description available WB:WBGene00050621 21ur-5078 No description available WB:WBGene00050622 21ur-2922 No description available WB:WBGene00050623 21ur-1455 No description available WB:WBGene00050624 21ur-2433 No description available WB:WBGene00050625 21ur-959 No description available WB:WBGene00050626 21ur-353 No description available WB:WBGene00050627 21ur-3632 Enriched in neurons based on RNA-seq studies. WB:WBGene00050628 21ur-3926 No description available WB:WBGene00050629 21ur-632 No description available WB:WBGene00050630 21ur-3777 No description available WB:WBGene00050631 21ur-3835 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00050632 21ur-2972 Enriched in neurons based on RNA-seq studies. WB:WBGene00050633 21ur-3450 No description available WB:WBGene00050634 21ur-4725 No description available WB:WBGene00050635 21ur-1246 No description available WB:WBGene00050636 21ur-4045 No description available WB:WBGene00050637 21ur-28 No description available WB:WBGene00050638 21ur-3533 No description available WB:WBGene00050639 21ur-757 No description available WB:WBGene00050640 21ur-219 No description available WB:WBGene00050641 21ur-3344 No description available WB:WBGene00050642 21ur-5260 No description available WB:WBGene00050643 21ur-1132 No description available WB:WBGene00050644 21ur-1464 No description available WB:WBGene00050645 21ur-4754 No description available WB:WBGene00050646 21ur-707 No description available WB:WBGene00050647 21ur-878 No description available WB:WBGene00050648 21ur-2370 No description available WB:WBGene00050649 21ur-446 No description available WB:WBGene00050650 21ur-1587 No description available WB:WBGene00050651 21ur-4167 No description available WB:WBGene00050652 21ur-4746 No description available WB:WBGene00050653 21ur-4572 No description available WB:WBGene00050654 21ur-434 No description available WB:WBGene00050655 21ur-3637 No description available WB:WBGene00050656 21ur-4347 No description available WB:WBGene00050657 21ur-735 No description available WB:WBGene00050658 21ur-5098 No description available WB:WBGene00050659 21ur-1142 No description available WB:WBGene00050660 21ur-4979 No description available WB:WBGene00050661 21ur-2306 Is affected by ikb-1 based on RNA-seq studies. WB:WBGene00050662 21ur-495 No description available WB:WBGene00050663 21ur-3701 No description available WB:WBGene00050664 21ur-1492 Enriched in neurons based on RNA-seq studies. WB:WBGene00050665 21ur-4689 No description available WB:WBGene00050666 21ur-1803 No description available WB:WBGene00050667 21ur-4598 No description available WB:WBGene00050668 21ur-625 No description available WB:WBGene00050669 21ur-4957 No description available WB:WBGene00050670 21ur-1061 No description available WB:WBGene00050671 21ur-4929 No description available WB:WBGene00050672 21ur-2095 No description available WB:WBGene00050673 21ur-3910 No description available WB:WBGene00050674 21ur-3033 No description available WB:WBGene00050675 21ur-3727 Is affected by meg-3 and meg-4 based on RNA-seq studies. WB:WBGene00050676 21ur-1720 No description available WB:WBGene00050677 21ur-1997 No description available WB:WBGene00050678 21ur-2745 No description available WB:WBGene00050679 21ur-3791 No description available WB:WBGene00050680 21ur-271 No description available WB:WBGene00050681 21ur-1614 No description available WB:WBGene00050682 21ur-4461 No description available WB:WBGene00050683 21ur-1709 No description available WB:WBGene00050684 21ur-405 No description available WB:WBGene00050685 21ur-1970 No description available WB:WBGene00050686 21ur-2116 Enriched in neurons based on RNA-seq studies. WB:WBGene00050687 21ur-1094 No description available WB:WBGene00050688 21ur-379 No description available WB:WBGene00050689 21ur-4564 No description available WB:WBGene00050690 21ur-16 No description available WB:WBGene00050691 21ur-1685 No description available WB:WBGene00050692 21ur-4005 No description available WB:WBGene00050693 21ur-4769 No description available WB:WBGene00050694 21ur-4703 No description available WB:WBGene00050695 21ur-4238 No description available WB:WBGene00050696 21ur-2730 No description available WB:WBGene00050697 21ur-4557 No description available WB:WBGene00050698 21ur-1281 No description available WB:WBGene00050699 21ur-1121 No description available WB:WBGene00050700 21ur-2574 No description available WB:WBGene00050701 21ur-1846 No description available WB:WBGene00050702 21ur-2432 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00050703 21ur-1695 No description available WB:WBGene00050704 21ur-3519 No description available WB:WBGene00050705 21ur-4140 No description available WB:WBGene00050706 21ur-2793 No description available WB:WBGene00050707 21ur-5290 No description available WB:WBGene00050708 21ur-2010 No description available WB:WBGene00050709 21ur-3859 No description available WB:WBGene00050710 21ur-5322 No description available WB:WBGene00050711 21ur-5269 No description available WB:WBGene00050712 21ur-2781 No description available WB:WBGene00050713 21ur-4883 No description available WB:WBGene00050714 21ur-359 No description available WB:WBGene00050715 21ur-5084 No description available WB:WBGene00050716 21ur-1287 No description available WB:WBGene00050717 21ur-1432 No description available WB:WBGene00050718 21ur-3155 No description available WB:WBGene00050719 21ur-3198 No description available WB:WBGene00050720 21ur-4412 No description available WB:WBGene00050721 21ur-1459 No description available WB:WBGene00050722 21ur-4905 No description available WB:WBGene00050723 21ur-1518 No description available WB:WBGene00050724 21ur-3610 No description available WB:WBGene00050725 21ur-4866 No description available WB:WBGene00050726 21ur-4895 No description available WB:WBGene00050727 21ur-4894 No description available WB:WBGene00050728 21ur-5182 No description available WB:WBGene00050729 21ur-2478 No description available WB:WBGene00050730 21ur-4692 No description available WB:WBGene00050731 21ur-1573 No description available WB:WBGene00050732 21ur-450 No description available WB:WBGene00050733 21ur-5232 No description available WB:WBGene00050734 21ur-1027 No description available WB:WBGene00050735 21ur-2273 No description available WB:WBGene00050736 21ur-4697 No description available WB:WBGene00050737 21ur-3757 No description available WB:WBGene00050738 21ur-502 No description available WB:WBGene00050739 21ur-1717 No description available WB:WBGene00050740 21ur-2053 No description available WB:WBGene00050741 21ur-3459 No description available WB:WBGene00050742 21ur-3025 No description available WB:WBGene00050743 21ur-1510 No description available WB:WBGene00050744 21ur-348 No description available WB:WBGene00050745 21ur-831 No description available WB:WBGene00050746 21ur-1990 No description available WB:WBGene00050747 21ur-2523 No description available WB:WBGene00050748 21ur-659 No description available WB:WBGene00050749 21ur-2548 No description available WB:WBGene00050750 21ur-3394 No description available WB:WBGene00050751 21ur-5004 No description available WB:WBGene00050752 21ur-2754 No description available WB:WBGene00050753 21ur-652 No description available WB:WBGene00050754 21ur-3582 No description available WB:WBGene00050755 21ur-5390 No description available WB:WBGene00050756 21ur-1404 No description available WB:WBGene00050757 21ur-4294 No description available WB:WBGene00050758 21ur-922 No description available WB:WBGene00050759 21ur-2342 No description available WB:WBGene00050760 21ur-2989 No description available WB:WBGene00050761 21ur-1700 No description available WB:WBGene00050762 21ur-3760 No description available WB:WBGene00050763 21ur-5068 No description available WB:WBGene00050764 21ur-686 No description available WB:WBGene00050765 21ur-5311 No description available WB:WBGene00050766 21ur-1365 No description available WB:WBGene00050767 21ur-5130 No description available WB:WBGene00050768 21ur-5032 No description available WB:WBGene00050769 21ur-2689 No description available WB:WBGene00050770 21ur-79 No description available WB:WBGene00050771 21ur-2557 No description available WB:WBGene00050772 21ur-883 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00050773 21ur-4507 No description available WB:WBGene00050774 21ur-4838 No description available WB:WBGene00050775 21ur-2214 No description available WB:WBGene00050776 21ur-334 No description available WB:WBGene00050777 21ur-5159 No description available WB:WBGene00050778 21ur-4964 No description available WB:WBGene00050779 21ur-4374 No description available WB:WBGene00050780 21ur-3442 No description available WB:WBGene00050781 21ur-5270 No description available WB:WBGene00050782 21ur-2365 No description available WB:WBGene00050783 21ur-2201 No description available WB:WBGene00050784 21ur-587 No description available WB:WBGene00050785 21ur-2178 No description available WB:WBGene00050786 21ur-1271 No description available WB:WBGene00050787 21ur-119 No description available WB:WBGene00050788 21ur-4941 No description available WB:WBGene00050789 21ur-4526 No description available WB:WBGene00050790 21ur-4777 No description available WB:WBGene00050791 21ur-2565 No description available WB:WBGene00050792 21ur-440 No description available WB:WBGene00050793 21ur-1980 No description available WB:WBGene00050794 21ur-748 No description available WB:WBGene00050795 21ur-2037 No description available WB:WBGene00050796 21ur-386 No description available WB:WBGene00050797 21ur-3504 No description available WB:WBGene00050798 21ur-5154 Enriched in neurons based on RNA-seq studies. WB:WBGene00050799 21ur-3691 No description available WB:WBGene00050800 21ur-1114 No description available WB:WBGene00050801 21ur-3051 No description available WB:WBGene00050802 21ur-1605 No description available WB:WBGene00050803 21ur-2542 No description available WB:WBGene00050804 21ur-4504 No description available WB:WBGene00050805 21ur-4333 No description available WB:WBGene00050806 21ur-5443 No description available WB:WBGene00050807 21ur-4516 Enriched in neurons based on RNA-seq studies. WB:WBGene00050808 21ur-3070 No description available WB:WBGene00050809 21ur-778 No description available WB:WBGene00050810 21ur-3177 No description available WB:WBGene00050811 21ur-4024 No description available WB:WBGene00050812 21ur-4492 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00050813 21ur-891 No description available WB:WBGene00050814 21ur-2986 No description available WB:WBGene00050815 21ur-3991 No description available WB:WBGene00050816 21ur-4709 No description available WB:WBGene00050817 21ur-4583 No description available WB:WBGene00050818 21ur-1551 No description available WB:WBGene00050819 21ur-3841 No description available WB:WBGene00050820 21ur-5160 No description available WB:WBGene00050821 21ur-3234 No description available WB:WBGene00050822 21ur-2682 No description available WB:WBGene00050823 21ur-5039 No description available WB:WBGene00050824 21ur-1908 No description available WB:WBGene00050825 21ur-2545 Enriched in neurons based on RNA-seq studies. WB:WBGene00050826 21ur-4455 No description available WB:WBGene00050827 21ur-3483 No description available WB:WBGene00050828 21ur-3487 No description available WB:WBGene00050829 21ur-5405 Enriched in neurons based on RNA-seq studies. WB:WBGene00050830 21ur-2444 No description available WB:WBGene00050831 21ur-4533 No description available WB:WBGene00050832 21ur-3006 No description available WB:WBGene00050833 21ur-3278 No description available WB:WBGene00050834 21ur-4719 No description available WB:WBGene00050835 21ur-3461 No description available WB:WBGene00050836 21ur-1568 No description available WB:WBGene00050837 21ur-1890 Is affected by spr-5 based on RNA-seq studies. WB:WBGene00050838 21ur-4252 No description available WB:WBGene00050839 21ur-339 No description available WB:WBGene00050840 21ur-1597 No description available WB:WBGene00050841 21ur-317 No description available WB:WBGene00050842 21ur-4034 No description available WB:WBGene00050843 21ur-5219 No description available WB:WBGene00050844 21ur-3402 No description available WB:WBGene00050845 21ur-3514 No description available WB:WBGene00050846 21ur-1733 No description available WB:WBGene00050847 21ur-952 No description available WB:WBGene00050848 21ur-5381 No description available WB:WBGene00050849 21ur-5422 No description available WB:WBGene00050850 21ur-3961 No description available WB:WBGene00050851 21ur-2770 No description available WB:WBGene00050852 21ur-2138 No description available WB:WBGene00050853 21ur-4218 No description available WB:WBGene00050854 21ur-1520 No description available WB:WBGene00050855 21ur-671 No description available WB:WBGene00050856 21ur-1215 No description available WB:WBGene00050857 21ur-3116 No description available WB:WBGene00050858 21ur-3063 No description available WB:WBGene00050859 21ur-3263 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00050860 21ur-4211 Enriched in neurons based on RNA-seq studies. WB:WBGene00050861 21ur-3412 No description available WB:WBGene00050862 21ur-5288 No description available WB:WBGene00050863 21ur-1576 No description available WB:WBGene00050864 21ur-3508 No description available WB:WBGene00050865 21ur-4862 No description available WB:WBGene00050866 21ur-326 No description available WB:WBGene00050867 21ur-979 No description available WB:WBGene00050868 21ur-5023 No description available WB:WBGene00050869 21ur-2916 No description available WB:WBGene00050870 21ur-4922 No description available WB:WBGene00050871 21ur-5108 No description available WB:WBGene00050873 21ur-1607 No description available WB:WBGene00050874 21ur-1635 No description available WB:WBGene00050875 bah-1 Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. Expressed in seam cell. Used to study bacterial infectious disease. WB:WBGene00050876 bah-2 No description available WB:WBGene00050877 bah-3 No description available WB:WBGene00050878 Y71A12C.3 Is affected by several genes including mex-1; spn-4; and adr-1 based on RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00050879 D1081.11 Predicted to be located in membrane. WB:WBGene00050880 F32H2.12 Is affected by several genes including daf-2; eat-2; and bar-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including mianserin; multi-walled carbon nanotube; and Rifampin based on RNA-seq studies. WB:WBGene00050881 ZK39.10 Predicted to be located in membrane. WB:WBGene00050883 Y102A5C.38 Is affected by several genes including daf-16; eat-2; and sek-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00050884 Y69H2.15 Enriched in AFD; body wall muscle cell; head mesodermal cell; and muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including skn-1; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. Is predicted to encode a protein with the following domains: SKP1/BTB/POZ domain superfamily and BTB/POZ domain. WB:WBGene00050885 Y94H6A.12 Predicted to enable aminoacyl-tRNA hydrolase activity. Is an ortholog of human PTRHD1 (peptidyl-tRNA hydrolase domain containing 1). WB:WBGene00050889 T04C12.9 Predicted to be located in membrane. WB:WBGene00050890 F17C11.16 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00050891 C08E8.9 Enriched in ASEL; ASER; PLM; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by hpl-2; hda-2; and etr-1 based on tiling array and RNA-seq studies. WB:WBGene00050892 ttr-57 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by several genes including daf-2; eat-2; and eri-1 based on RNA-seq and microarray studies. Is affected by Doxycycline; paraquat; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00050893 Y94A7B.11 Predicted to be involved in protein import into mitochondrial matrix and protein insertion into mitochondrial inner membrane. Predicted to be located in membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. WB:WBGene00050894 F49H6.15 Is affected by clk-1; daf-2; and eat-2 based on microarray studies. Is affected by tryptophan and Microcystin-LR based on microarray studies. WB:WBGene00050896 ttr-56 Predicted to be located in cell surface and extracellular region. WB:WBGene00050897 C47A10.13 No description available WB:WBGene00050898 T19B10.12 Is affected by several genes including daf-2; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by seven chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq studies. WB:WBGene00050899 T10C6.15 Enriched in AVDL; AVDR; head mesodermal cell; and pharyngeal-intestinal valve based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including sodium arsenite; Cadmium Chloride; and Sodium Chloride based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box-like domain superfamily. WB:WBGene00050900 ZK228.11 Is affected by several genes including daf-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00050902 T26F2.4 No description available WB:WBGene00050903 Y17D7C.4 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by nine chemicals including 1-methylnicotinamide; Alovudine; and Zidovudine based on RNA-seq studies. WB:WBGene00050904 Y70C5A.3 Enriched in ABplapapppp; ABprapapppp; head mesodermal cell; and intestine based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including Tunicamycin; levamisole; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00050906 F20E11.17 Enriched in dopaminergic neurons; excretory cell; and intestine based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Tunicamycin; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00050907 Y51A2B.9 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-16; hpl-2; and ain-1 based on tiling array; microarray; and RNA-seq studies. Is affected by tryptophan; antimycin; and Colistin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function and Domain of unknown function WSN. WB:WBGene00050910 Y43F8B.17 Is affected by several genes including clk-1; pgl-1; and glh-1 based on microarray and RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00050911 Y43F8B.18 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00050912 F43E2.12 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including manganese chloride; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00050913 T12B5.14 Predicted to be located in membrane. WB:WBGene00050914 T12B5.15 Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by fifteen chemicals including Ethanol; rotenone; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00050915 Y6E2A.10 Enriched in coelomocyte; neurons; pm6; and in male based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by sixteen chemicals including Ethanol; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00050916 F55F10.3 Predicted to be located in membrane. WB:WBGene00050917 Y53G8AL.4 Predicted to be involved in circadian rhythm. WB:WBGene00050918 mig-35 No description available WB:WBGene00050919 C45G9.15 Enriched in neurons and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and isp-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF851 and Protein of unknown function (DUF851). WB:WBGene00050920 Y54H5A.5 Enriched in germ line based on RNA-seq studies. Is affected by several genes including eat-2; met-2; and hpl-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and atracurium based on RNA-seq studies. WB:WBGene00050921 mir-1019 Is affected by alg-5 based on RNA-seq studies. Is affected by nicotine based on RNA-seq studies. WB:WBGene00050922 mir-1020 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. WB:WBGene00050923 mir-1021 No description available WB:WBGene00050924 mir-1018 Is affected by several genes including eat-2; prg-1; and meg-3 based on RNA-seq studies. Is affected by nicotine and multi-walled carbon nanotube based on quantitative PCR and RNA-seq studies. WB:WBGene00050926 B0250.11 Is affected by several genes including pgl-1; glh-1; and dpy-21 based on RNA-seq studies. Is affected by Rifampin; Sirolimus; and allantoin based on RNA-seq and microarray studies. WB:WBGene00050927 B0250.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00050928 F49H6.16 Is affected by daf-2 based on microarray studies. WB:WBGene00050929 F58D12.5 Enriched in ASER based on RNA-seq studies. Is affected by mes-4 and mrg-1 based on RNA-seq studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00050930 T08G5.13 Is affected by mut-16 based on RNA-seq studies. WB:WBGene00050931 F59B2.14 Enriched in excretory gland cell; neuronal sheath cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by etr-1 and hlh-26 based on RNA-seq studies. Is predicted to encode a protein with the following domain: Zinc finger C2H2-type. WB:WBGene00050932 F46B3.19 Enriched in NSM and hypodermis based on tiling array studies. Is affected by several genes including clk-1; hsp-6; and bar-1 based on microarray and RNA-seq studies. Is affected by Colistin based on microarray studies. WB:WBGene00050933 T19C9.9 Is affected by smn-1 and qui-1 based on RNA-seq studies. Is affected by triclosan based on microarray studies. WB:WBGene00050934 T19C9.10 Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA helicase activity. Predicted to be involved in DNA duplex unwinding and DNA metabolic process. WB:WBGene00050935 Y37H2A.16 Enriched in muscle cell based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00050936 ZK856.16 Enriched in several structures, including ABplapaaaa; ABplppppap; ABprapaaaa; AFD; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; pgl-1; and fog-2 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by four chemicals including rotenone; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00050937 R02D5.8 Enriched in germ line; head mesodermal cell; and neurons based on RNA-seq and microarray studies. Is affected by several genes including eat-2; pgl-1; and isp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. Is an ortholog of human DMAC2L (distal membrane arm assembly component 2 like). WB:WBGene00050938 F23H12.11 Is affected by clk-1 based on microarray studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00050939 C05G5.7 Enriched in several structures, including AFD; M cell; arcade cell; muscle cell; and pharyngeal neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and sek-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including 1-methylnicotinamide; nicotinic acid; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00050940 C25D7.16 Predicted to be located in ribosome. WB:WBGene00050941 C33F10.14 Predicted to enable NAD binding activity and oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. Predicted to be involved in import into nucleus. Predicted to be located in cytoplasm. Is an ortholog of human HTATIP2 (HIV-1 Tat interactive protein 2). WB:WBGene00050943 ZC412.10 Enriched in several structures, including dopaminergic neurons; hypodermis; interfacial epithelial cell; mechanosensory neurons; and rectal gland cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including 1-methylnicotinamide; Tunicamycin; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00050944 C14A11.9 Enriched in CEP socket cell; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including pgl-1; isp-1; and prg-1 based on RNA-seq; tiling array; and microarray studies. Is affected by five chemicals including rotenone; paraquat; and Diazinon based on RNA-seq and microarray studies. WB:WBGene00050945 C45B11.7 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00050946 M162.12 Is affected by several genes including glp-1; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Ethanol; D-glucopyranose; and Rifampin based on RNA-seq studies. WB:WBGene00050947 K07C5.13 Enriched in ABplaapaap; ABplppaapa; ABpraapaap; and ABprppaapa based on single-cell RNA-seq studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Tunicamycin; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00050948 Y48B6A.16 Is affected by several genes including pgl-1; unc-30; and atfs-1 based on RNA-seq and microarray studies. Is affected by four chemicals including rotenone; stavudine; and metformin based on RNA-seq studies. WB:WBGene00050949 K08G2.16 Is affected by clk-1 based on microarray studies. WB:WBGene00050950 Y60A3A.28 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00050951 T26H2.11 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. WB:WBGene00050954 K06B4.14 Is affected by several genes including daf-2; eat-2; and isp-1 based on microarray studies. Is affected by Hydrolyzable Tannins; paraquat; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00050955 C14A6.12 Predicted to be located in membrane. WB:WBGene00050956 C14A6.13 Predicted to be located in membrane. WB:WBGene00050957 C10A4.10 Predicted to be located in membrane. WB:WBGene00050958 F28B1.10 Is affected by CGP37157 based on RNA-seq studies. WB:WBGene00050959 F26F2.9 Is affected by several genes including nhr-49; bar-1; and mir-35 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00050960 T03E6.10 No description available WB:WBGene00050961 T03E6.11 Is affected by daf-2; eat-2; and etr-1 based on microarray and RNA-seq studies. Is affected by tetrabromobisphenol A and Microcystin-LR based on microarray studies. WB:WBGene00050962 F49A5.11 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00050963 ZK218.15 No description available WB:WBGene00050964 Y50E8A.18 Is affected by hpl-2; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00050965 F49H6.17 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00050967 C25F9.15 Enriched in AFD and RMD based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; elt-2; and clk-1 based on microarray and RNA-seq studies. Is affected by antimycin and nitroguanidine based on RNA-seq and microarray studies. WB:WBGene00050968 R11G10.4 Enriched in AVK and in male based on RNA-seq studies. Is affected by several genes including rrf-3; tph-1; and cat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00050970 D2023.8 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; sek-1; and hpl-2 based on RNA-seq studies. Is affected by metformin; cholesterol; and paraquat based on RNA-seq studies. WB:WBGene00050971 F11D11.15 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00050972 T23D5.13 Is affected by daf-2 and sir-2.1 based on microarray studies. WB:WBGene00050973 Y26G10.3 Enriched in male based on RNA-seq studies. Is affected by dpy-21 and let-60 based on RNA-seq and microarray studies. WB:WBGene00050974 Y6G8.9 Enriched in ASER; PLM; and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00050976 F28B1.11 Is affected by clk-1 based on microarray studies. WB:WBGene00050977 F56H9.7 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by hmg-3; hda-2; and etr-1 based on RNA-seq studies. WB:WBGene00050978 som-1 No description available WB:WBGene00050980 som-3 No description available WB:WBGene00050981 som-4 No description available WB:WBGene00077434 F46B3.20 Enriched in AVK based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00077436 F46B3.22 Is affected by several genes including daf-16; daf-12; and clk-1 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; Atrazine; and Colistin based on RNA-seq and microarray studies. WB:WBGene00077437 Y59H11AR.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; glp-1; and rrf-3 based on RNA-seq studies. Is affected by eight chemicals including rotenone; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00077438 C18D4.10 Is affected by several genes including clk-1; tph-1; and cat-2 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00077439 F55B12.10 Enriched in several structures, including germ line; interfacial epithelial cell; male distal tip cell; mechanosensory neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00077440 Y75B12B.14 Is affected by clk-1 and hmg-3 based on microarray and RNA-seq studies. WB:WBGene00077441 C43D7.10 Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00077442 F11D11.16 No description available WB:WBGene00077443 Y71A12B.19 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00077444 F54B8.17 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00077445 Y51A2A.12 Enriched in body wall muscle cell; dopaminergic neurons; and hypodermis based on tiling array studies. Is affected by several genes including daf-2; eat-2; and tax-6 based on RNA-seq and microarray studies. WB:WBGene00077446 F49A5.12 Is affected by pmk-1 based on microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00077447 C14A6.14 Is affected by clk-1 and his-3 based on microarray and RNA-seq studies. WB:WBGene00077448 D1086.20 Is affected by several genes including hsf-1; nhr-49; and unc-30 based on RNA-seq studies. Is affected by seven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00077449 C08B6.15 Is affected by tatn-1; daf-2; and mut-16 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00077450 K06B4.15 Predicted to be located in membrane. WB:WBGene00077451 Y69H2.16 Is affected by several genes including daf-2; eat-2; and cpl-1 based on RNA-seq and microarray studies. Is affected by nitroguanidine based on microarray studies. WB:WBGene00077452 Y62F5A.11 Is affected by clk-1 based on microarray studies. WB:WBGene00077453 Y62F5A.12 Predicted to enable RNA-directed DNA polymerase activity. Predicted to be involved in RNA-templated DNA biosynthetic process. WB:WBGene00077454 Y17D7C.5 No description available WB:WBGene00077455 Y69H2.17 Enriched in lateral ganglion and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-12; eat-2; and alg-1 based on RNA-seq and microarray studies. Is affected by four chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily and CUB domain. WB:WBGene00077456 T23D5.14 No description available WB:WBGene00077457 Y39B6A.49 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and hsp-6 based on RNA-seq studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00077459 Y6G8.10 No description available WB:WBGene00077460 Y6G8.11 Is affected by Colistin based on microarray studies. WB:WBGene00077461 F12F6.11 Is affected by several genes including daf-2; prg-1; and dpy-21 based on RNA-seq studies. WB:WBGene00077462 JC8.15 Is affected by cep-1; dlc-1; and car-1 based on RNA-seq studies. WB:WBGene00077463 T03E6.12 Is affected by clk-1 based on microarray studies. WB:WBGene00077464 Y70C5B.2 Predicted to be located in membrane. WB:WBGene00077465 rrn-4.2 Is affected by several genes including lag-1; hpl-2; and etr-1 based on RNA-seq studies. WB:WBGene00077466 rrn-4.3 Is affected by clk-1 and pptr-1 based on microarray and RNA-seq studies. WB:WBGene00077467 rrn-4.4 Is affected by cep-1 and swsn-9 based on RNA-seq studies. WB:WBGene00077468 rrn-4.5 No description available WB:WBGene00077469 rrn-4.6 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00077470 rrn-4.7 No description available WB:WBGene00077471 rrn-4.8 No description available WB:WBGene00077472 rrn-4.9 No description available WB:WBGene00077473 rrn-4.10 No description available WB:WBGene00077474 rrn-4.11 No description available WB:WBGene00077475 rrn-4.12 Is affected by adr-1 and etr-1 based on RNA-seq studies. WB:WBGene00077476 rrn-4.13 No description available WB:WBGene00077477 rrn-4.14 No description available WB:WBGene00077478 sls-1.1 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00077479 sls-1.2 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00077480 sls-1.3 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00077481 sls-1.4 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00077482 sls-1.5 Is affected by several genes including daf-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00077483 sls-1.6 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00077484 sls-1.7 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00077485 sls-1.8 Is affected by several genes including daf-16; sek-1; and pgl-1 based on RNA-seq studies. WB:WBGene00077486 sls-1.9 Is affected by several genes including daf-16; daf-2; and sek-1 based on RNA-seq and microarray studies. WB:WBGene00077487 sls-1.11 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00077488 sls-1.12 Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00077489 C04G6.13 Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including pmk-1; clk-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including sodium arsenite; D-glucose; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00077490 M03A1.8 Predicted to be located in membrane. WB:WBGene00077491 K08H10.10 Enriched in intestine and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including D-glucose; Alovudine; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00077492 F09C6.15 Is affected by ubc-9 based on microarray studies. Is affected by Tunicamycin based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00077493 F09C6.16 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00077494 F28B1.12 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00077495 Y20C6A.4 Enriched in ABplapppaa; ABprapppaa; and pm8 based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00077496 F11A3.4 Enriched in intestine and in male based on RNA-seq and microarray studies. Is affected by daf-2; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00077497 K06A4.10 Predicted to be located in membrane. WB:WBGene00077498 R07B5.10 Is affected by clk-1; dlc-1; and eat-2 based on microarray and RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00077499 T11A5.8 No description available WB:WBGene00077500 C27H6.9 Predicted to enable single-stranded DNA exodeoxyribonuclease activity. Predicted to be involved in mitochondrial DNA replication. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 11. Is an ortholog of human MGME1 (mitochondrial genome maintenance exonuclease 1). WB:WBGene00077501 K08H10.11 Is affected by several genes including hpl-2; mrps-5; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00077502 AC3.11 No description available WB:WBGene00077503 AC3.12 Predicted to enable transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to be located in membrane. WB:WBGene00077504 AC3.13 Is affected by several genes including daf-16; clk-1; and hsp-6 based on microarray and RNA-seq studies. WB:WBGene00077506 F25D1.7 Is affected by eat-2 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00077508 T27F6.10 Predicted to be located in membrane. WB:WBGene00077510 Y42A5A.6 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00077514 F07B10.7 Predicted to be located in membrane. WB:WBGene00077515 E01A2.9 Is affected by several genes including clk-1; pgl-1; and glh-1 based on microarray and RNA-seq studies. WB:WBGene00077516 C50C3.13 Is affected by several genes including clk-1; prg-1; and dlc-1 based on RNA-seq and microarray studies. WB:WBGene00077517 C50C3.14 Is affected by cep-1 and sftb-1 based on RNA-seq studies. WB:WBGene00077519 T27C10.8 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including rotenone; Sodium Chloride; and allantoin based on RNA-seq and microarray studies. WB:WBGene00077520 C37A5.11 Predicted to be located in membrane. WB:WBGene00077521 maf-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including Ayme-Gripp syndrome; Duane retraction syndrome; and cataract 21 multiple types. Is an ortholog of human MAFF (MAF bZIP transcription factor F); MAFG (MAF bZIP transcription factor G); and MAFK (MAF bZIP transcription factor K). WB:WBGene00077522 T10D4.15 Enriched in ASH; neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00077523 C23H5.12 Predicted to be located in membrane. WB:WBGene00077524 F36D1.11 Is affected by sir-2.1 based on microarray studies. WB:WBGene00077525 C41G7.8 Predicted to be located in membrane. WB:WBGene00077526 C25A1.16 Enriched in ASER; M cell; germ line; intestine; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including mianserin; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00077527 C25A1.17 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00077528 Y26D4A.20 No description available WB:WBGene00077529 jud-1 No description available WB:WBGene00077530 jud-2 No description available WB:WBGene00077531 F40G9.15 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; pharyngeal cell; and rectal epithelium based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including 1-methylnicotinamide; mianserin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00077532 jud-3 No description available WB:WBGene00077534 F41D3.14 Is affected by ahr-1 and fzo-1 based on RNA-seq studies. WB:WBGene00077535 F15H9.7 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00077536 F38B7.10 Predicted to be located in membrane. WB:WBGene00077537 Y47H10A.6 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and unc-30 based on RNA-seq studies. Is affected by four chemicals including Rifampin; Sirolimus; and Doxycycline based on RNA-seq studies. WB:WBGene00077538 T04F3.5 Enriched in AFD and ASER based on RNA-seq studies. Is affected by several genes including sek-1; nhr-23; and hpl-2 based on tiling array; microarray; and RNA-seq studies. Is affected by tryptophan; Tunicamycin; and allantoin based on microarray studies. WB:WBGene00077539 Y52B11A.12 Enriched in several structures, including ABplaapaaa; ABplaapaap; hyp3; interfacial epithelial cell; and rect_D based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and elt-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including mianserin; Alovudine; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00077540 lsy-23 No description available WB:WBGene00077541 lsy-24 No description available WB:WBGene00077543 F27D4.8 Predicted to be located in membrane. WB:WBGene00077546 C01A2.9 Predicted to be located in membrane. WB:WBGene00077548 F21C3.7 Predicted to be located in membrane. WB:WBGene00077549 F11A6.3 Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00077550 Y106G6G.8 No description available WB:WBGene00077551 H15N14.3 Is affected by eat-2 based on microarray studies. WB:WBGene00077552 H15N14.4 Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00077553 C26C6.10 Enriched in AFD; OLL; PVD; and intestine based on tiling array and RNA-seq studies. Is affected by several genes including elt-2; aak-2; and unc-30 based on microarray and RNA-seq studies. Is affected by Tunicamycin; Zidovudine; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00077555 F28C12.8 Is affected by clk-1 based on microarray studies. WB:WBGene00077556 Y18D10A.27 Is affected by several genes including eat-2; pgl-1; and alg-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00077557 F15D3.9 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00077558 T06D10.3 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; hlh-30; and smg-1 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; stavudine; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00077559 R05D7.7 Predicted to be located in membrane. WB:WBGene00077561 W05H12.3 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. Is affected by Psoralens and allantoin based on RNA-seq studies. WB:WBGene00077562 ZC443.7 Predicted to be located in membrane. WB:WBGene00077563 peel-1 Predicted to be located in membrane. Expressed in spermatocyte. WB:WBGene00077564 C44H9.9 Is affected by several genes including clk-1; pgl-1; and glh-1 based on microarray and RNA-seq studies. Is affected by stavudine based on RNA-seq studies. WB:WBGene00077565 W07G4.7 Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies. Is affected by tryptophan and dafa#1 based on microarray studies. WB:WBGene00077566 C34B4.6 Is affected by clk-1 based on microarray studies. WB:WBGene00077567 Y2H9A.5 No description available WB:WBGene00077568 C56A3.10 Is affected by several genes including daf-16; met-2; and set-25 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00077569 F53F4.18 Predicted to be located in membrane. WB:WBGene00077570 F55B12.11 Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including allantoin; Sirolimus; and metformin based on RNA-seq studies. WB:WBGene00077571 T26F2.5 No description available WB:WBGene00077572 T08G5.14 Is affected by several genes including lin-35; alg-1; and lagr-1 based on RNA-seq and microarray studies. WB:WBGene00077573 T08G5.15 Enriched in AIZ and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00077574 T08G5.16 Is affected by eat-2; ints-8; and sir-2.1 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00077575 F14D7.16 Is affected by eat-2 based on microarray studies. WB:WBGene00077576 C15H11.13 Predicted to be located in membrane. WB:WBGene00077577 R02D5.9 Predicted to be located in membrane. WB:WBGene00077579 R11H6.7 Enriched in male based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00077580 R08A2.8 No description available WB:WBGene00077581 H12D21.16 Is affected by adr-1; eat-2; and mrps-5 based on RNA-seq and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and Hydrolyzable Tannins based on RNA-seq and microarray studies. WB:WBGene00077582 F14H8.8 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00077583 C01G10.18 Enriched in NSM; body wall musculature; and germline precursor cell based on tiling array and microarray studies. Is affected by several genes including csr-1; drh-3; and nuo-6 based on RNA-seq and microarray studies. Is affected by resveratrol; adsorbable organic bromine compound; and Sirolimus based on microarray studies. WB:WBGene00077584 C01G10.19 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00077585 T01G5.8 Enriched in several structures, including ABalaapppp; ABalapaapp; ABalappppa; ABplppaapa; and ABprppaapa based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; D-glucose; and Psoralens based on RNA-seq studies. WB:WBGene00077586 T09F5.17 No description available WB:WBGene00077588 T26H8.5 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00077589 R08H2.15 No description available WB:WBGene00077590 R08H2.16 Is affected by clk-1 based on microarray studies. WB:WBGene00077592 T25B2.3 Enriched in ABalpppappp; ABpraaaappp; ALM; BDU; and hypodermis based on single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and aak-2 based on microarray and RNA-seq studies. Is affected by stavudine; Zidovudine; and Colistin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00077593 C49G7.12 Enriched in body wall muscle cell; cephalic sheath cell; coelomocyte; intestine; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on tiling array; microarray; and RNA-seq studies. Is affected by thirty chemicals including Nitric Oxide; 1-methylnicotinamide; and D-glucopyranose based on RNA-seq and microarray studies. WB:WBGene00077594 nhr-151 Enriched in sensory neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00077595 K06B4.16 Is affected by clk-1 based on microarray studies. WB:WBGene00077596 K06B4.17 Is affected by dpy-21 and qui-1 based on RNA-seq studies. WB:WBGene00077597 T23D5.15 Is affected by dpy-21 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00077598 T23D5.16 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00077599 T20F5.8 Predicted to be located in membrane. WB:WBGene00077600 F54B8.18 Is affected by clk-1 based on microarray studies. WB:WBGene00077601 T06C12.17 Is affected by daf-19 based on microarray studies. Is affected by Ag nanoparticles based on microarray studies. WB:WBGene00077602 F35E8.15 Is affected by daf-2 based on microarray studies. WB:WBGene00077603 T05G11.9 Is affected by swsn-1 based on RNA-seq studies. WB:WBGene00077604 H24D24.3 No description available WB:WBGene00077605 F36G9.17 Is affected by daf-2 based on microarray studies. WB:WBGene00077606 C06C6.10 Enriched in intestine based on microarray studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00077607 T10C6.16 Enriched in NSM and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and unc-30 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00077608 F22B8.9 Is affected by clk-1 based on microarray studies. WB:WBGene00077609 F44G3.15 Is affected by clk-1 based on microarray studies. WB:WBGene00077610 F44G3.16 No description available WB:WBGene00077611 F11A5.19 Is affected by ints-5 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00077612 F21H7.15 No description available WB:WBGene00077613 F21H7.16 Is affected by ints-5 and qui-1 based on RNA-seq studies. WB:WBGene00077614 C31A11.12 Is affected by clk-1 based on microarray studies. WB:WBGene00077615 T08G3.14 Is affected by nhr-49 based on RNA-seq studies. WB:WBGene00077616 F57E7.4 Enriched in AVE and amphid sheath cell based on tiling array and RNA-seq studies. Is affected by several genes including clk-1; nhr-49; and mex-3 based on tiling array; RNA-seq; and microarray studies. Is affected by antimycin and CGP37157 based on RNA-seq studies. WB:WBGene00077617 F57E7.5 No description available WB:WBGene00077618 F57E7.6 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00077619 F36D3.15 Is affected by hrpr-1; hpl-2; and swsn-1 based on RNA-seq studies. WB:WBGene00077620 W06G6.16 Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies. WB:WBGene00077621 Y70C5C.8 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00077622 T25E12.14 Is affected by several genes including alg-1; set-2; and adr-1 based on RNA-seq studies. WB:WBGene00077624 Y102A5C.40 Is affected by Atrazine and Sirolimus based on microarray studies. WB:WBGene00077625 Y102A5C.41 No description available WB:WBGene00077626 Y102A5C.42 No description available WB:WBGene00077627 T19C9.11 Is affected by clk-1; smn-1; and qui-1 based on microarray and RNA-seq studies. WB:WBGene00077629 K10G4.13 Is affected by several genes including skn-1; glp-1; and hsf-1 based on RNA-seq studies. Is affected by ten chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00077630 F31E9.10 No description available WB:WBGene00077631 T27C5.15 Is affected by qui-1 based on RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00077632 T27C5.16 Is affected by clk-1 based on microarray studies. Is affected by Progesterone based on microarray studies. WB:WBGene00077633 T27C5.17 No description available WB:WBGene00077634 Y46G5A.41 Is affected by dpy-21; ain-1; and ain-2 based on RNA-seq and microarray studies. WB:WBGene00077635 Y46G5A.42 Is affected by clk-1; eat-2; and xpf-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on RNA-seq studies. WB:WBGene00077636 Y46G5A.43 Enriched in sensory neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Alovudine; metformin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00077637 Y6G8.12 No description available WB:WBGene00077638 Y6G8.13 Is affected by several genes including eat-2; clk-1; and tph-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00077640 Y26G10.4 Predicted to be located in membrane. WB:WBGene00077641 Y94A7B.12 Is affected by several genes including clk-1; pgl-1; and glh-1 based on microarray and RNA-seq studies. WB:WBGene00077642 C14A6.15 Is affected by mrps-5 based on microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00077643 trpp-1 Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be part of TRAPP complex. Is an ortholog of human TRAPPC1 (trafficking protein particle complex subunit 1). WB:WBGene00077644 Y37H2C.5 No description available WB:WBGene00077646 Y51A2A.14 Is affected by Sirolimus based on microarray studies. WB:WBGene00077647 Y51A2A.15 Is affected by mrps-5 based on microarray studies. WB:WBGene00077648 Y51A2B.10 Is affected by sir-2.1 based on microarray studies. WB:WBGene00077649 Y51A2B.11 Is affected by adr-1; eat-2; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00077650 ZK262.14 No description available WB:WBGene00077651 ZK262.15 Is affected by clk-1 and smn-1 based on microarray and RNA-seq studies. WB:WBGene00077652 ZK228.12 Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Alovudine; stavudine; and Rifampin based on RNA-seq studies. WB:WBGene00077653 Y51A2D.23 Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00077654 Y69H2.18 Is affected by clk-1 based on microarray studies. WB:WBGene00077655 asp-19 Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); chronic fatigue syndrome; and congenital adrenal hyperplasia. Is an ortholog of human REN (renin). WB:WBGene00077656 F11D11.17 Is affected by mrps-5 based on microarray studies. WB:WBGene00077657 F11D11.18 Is affected by several genes including sir-2.1; clk-1; and pgl-1 based on microarray and RNA-seq studies. WB:WBGene00077658 M106.8 Predicted to be located in membrane. WB:WBGene00077659 F11D11.19 Is affected by several genes including daf-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by dafa#1 and Sirolimus based on microarray studies. WB:WBGene00077660 Y17D7B.9 Is affected by daf-16; sir-2.1; and spg-7 based on RNA-seq and microarray studies. Is affected by Cry5B and Sirolimus based on microarray studies. WB:WBGene00077662 T26H2.12 Is affected by chd-3; srbc-48; and hda-2 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00077663 F55C9.14 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalpppapa; amphid sensillum; and excretory system based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; stavudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00077664 C43D7.11 Is affected by several genes including daf-2; eat-2; and let-418 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00077666 M162.13 Is affected by mrps-5 based on microarray studies. WB:WBGene00077667 M162.14 No description available WB:WBGene00077669 Y38H6A.5 Enriched in several structures, including AFD; accessory cell; lateral ganglion; motor neurons; and rectal epithelium based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including stavudine; Zidovudine; and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00077670 K02E2.9 Is affected by sams-3 based on RNA-seq studies. Is affected by Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00077671 K02E2.10 Is affected by clk-1 based on microarray studies. WB:WBGene00077672 B0250.13 No description available WB:WBGene00077673 B0563.10 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and elt-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Tunicamycin; Alovudine; and tert-Butylhydroperoxide based on microarray and RNA-seq studies. WB:WBGene00077674 K02A6.4 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00077675 cin-1 No description available WB:WBGene00077676 cin-2 No description available WB:WBGene00077677 cin-3 No description available WB:WBGene00077678 cin-5 No description available WB:WBGene00077679 K11E4.6 Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. WB:WBGene00077680 F54F7.10 Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be part of elongin complex. Is an ortholog of human ELOC (elongin C). WB:WBGene00077681 Y44A6D.7 Predicted to be located in membrane. WB:WBGene00077682 F58B4.7 Is affected by several genes including skn-1; hsf-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Tunicamycin; Cry5B; and cholesterol based on microarray and RNA-seq studies. WB:WBGene00077684 Y26D4A.21 Enriched in intestine and pharyngeal muscle cell based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including Tunicamycin; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies. WB:WBGene00077685 C04F12.12 Enriched in hypodermis and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by eight chemicals including D-glucose; Zidovudine; and antimycin based on RNA-seq and microarray studies. WB:WBGene00077686 T26E3.12 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00077687 Y52B11A.14 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on RNA-seq studies. Is affected by metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00077688 Y43F8B.19 Predicted to enable procollagen-proline 4-dioxygenase activity. Predicted to be located in endoplasmic reticulum. WB:WBGene00077689 Y105E8A.34 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including let-60; rrf-3; and sek-1 based on microarray and RNA-seq studies. Is affected by four chemicals including 1-methylnicotinamide; multi-walled carbon nanotube; and Rifampin based on RNA-seq studies. WB:WBGene00077690 mtp-18 Predicted to be involved in mitochondrial fission. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in Parkinson's disease 6 and neuroblastoma. Is an ortholog of human MTFP1 (mitochondrial fission process 1). WB:WBGene00077691 idpc-4 Enriched in arcade cell; hypodermis; intestine; pharyngeal muscle cell; and posterior arcade cell based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-five chemicals including Ethanol; methylmercury hydroxide; and 1-methylnicotinamide based on RNA-seq and microarray studies. WB:WBGene00077692 C08E8.10 Enriched in several structures, including PLM; cephalic sheath cell; dopaminergic neurons; germline precursor cell; and somatic gonad precursor based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including rotenone; sodium arsenite; and multi-walled carbon nanotube based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00077693 T04C12.11 Predicted to be located in membrane. WB:WBGene00077694 C43D7.12 Is affected by dpy-21 and etr-1 based on RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00077695 F14D7.17 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00077696 marc-1 Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in membrane. WB:WBGene00077697 F58E6.13 Enriched in epithelial cell; head mesodermal cell; hypodermis; neurons; and somatic gonad precursor based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on microarray; proteomic; tiling array; and RNA-seq studies. Is affected by twenty-seven chemicals including Nitric Oxide; methylmercury hydroxide; and nicotinic acid based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Growth factor receptor cysteine-rich domain superfamily; EGF domain; Tyrosine-protein kinase ephrin type A/B receptor-like; and EGF-like domain. WB:WBGene00077698 lurp-4 Enriched in head mesodermal cell and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and elt-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including 1-methylnicotinamide; multi-walled carbon nanotube; and 4-bromodiphenyl ether based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Ly-6 antigen/uPA receptor-like and Snake toxin-like superfamily. WB:WBGene00077699 C45B11.8 Predicted to be located in membrane. WB:WBGene00077700 sex-2 Acts upstream of or within primary sex determination and transcription by RNA polymerase II. WB:WBGene00077701 poml-3 Enriched in ABplapaaaa; ABprapaaaa; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by twenty-one chemicals including manganese chloride; D-glucose; and 4-bromodiphenyl ether based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); eye disease (multiple); and hematologic cancer (multiple). Human PON1 enables several functions, including aryldialkylphosphatase activity; arylesterase activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: SMP-30/Gluconolactonase/LRE-like region and Six-bladed beta-propeller, TolB-like. Is an ortholog of human PON1 (paraoxonase 1); PON2 (paraoxonase 2); and PON3 (paraoxonase 3). WB:WBGene00077703 K08E5.5 Enriched in several structures, including ABplaapaaa; anterior hypodermis; excretory gland cell; interfacial epithelial cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00077704 F12A10.9 Is affected by several genes including rrf-3; eat-2; and dpy-7 based on RNA-seq and microarray studies. Is affected by seven chemicals including Sirolimus; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00077705 mir-1829.1 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by nicotine based on RNA-seq studies. WB:WBGene00077706 mir-1829.2 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eat-2; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR and RNA-seq studies. WB:WBGene00077707 mir-1829.3 Is affected by several genes including eat-2; glp-4; and prg-1 based on RNA-seq studies. Is affected by nicotine and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00077708 mir-1817 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR studies. WB:WBGene00077709 mir-1822 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by graphene oxide based on RNA-seq studies. WB:WBGene00077712 nipi-4 Predicted to enable signaling receptor binding activity. Involved in defense response to fungus; positive regulation of gene expression; and response to wounding. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Expressed in hypodermis. WB:WBGene00077713 nipi-5 No description available WB:WBGene00077714 R102.11 Enriched in hypodermis; interfacial epithelial cell; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by twelve chemicals including mianserin; D-glucose; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00077715 mir-1818 Is affected by alg-1; alg-2; and alg-5 based on RNA-seq studies. WB:WBGene00077716 mir-1819 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00077717 mir-1823 Is affected by alg-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00077718 mir-1824 Enriched in neurons based on RNA-seq studies. Is affected by several genes including alg-1; alg-2; and alg-5 based on RNA-seq studies. WB:WBGene00077719 mir-1828 Is affected by alg-5 based on RNA-seq studies. Is affected by nicotine based on RNA-seq studies. WB:WBGene00077720 mir-1833 Is affected by nicotine based on quantitative PCR studies. WB:WBGene00077721 mir-1022 Expressed in sensory neurons; uterus; and vulva. WB:WBGene00077722 mir-58.2 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by nicotine and graphene oxide based on quantitative PCR and RNA-seq studies. WB:WBGene00077723 mir-1830 Is affected by several genes including eat-2; glp-4; and prg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and graphene oxide based on RNA-seq studies. WB:WBGene00077724 mir-1831 No description available WB:WBGene00077725 mir-1832.1 Is affected by several genes including eat-2; glp-4; and prg-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00077726 mir-1820 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine and graphene oxide based on quantitative PCR and RNA-seq studies. WB:WBGene00077727 mir-1821 Expressed in ASEL; ASER; and head neurons. WB:WBGene00077728 T23G11.11 Enriched in AFD and ASER based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and glh-1 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; D-glucose; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00077729 szy-1 Acts upstream of or within several processes, including embryo development; nematode larval development; and organelle organization. WB:WBGene00077731 szy-3 Acts upstream of or within centrosome duplication. WB:WBGene00077732 szy-4 Involved in regulation of centrosome duplication. WB:WBGene00077735 szy-7 Acts upstream of or within centrosome duplication. WB:WBGene00077736 szy-8 Acts upstream of or within centrosome duplication and embryo development. WB:WBGene00077737 szy-9 Acts upstream of or within centrosome duplication. WB:WBGene00077739 szy-11 Acts upstream of or within centrosome duplication and meiotic chromosome segregation. WB:WBGene00077740 szy-12 Acts upstream of or within centrosome duplication. WB:WBGene00077742 szy-14 Acts upstream of or within centrosome duplication. WB:WBGene00077743 szy-15 Acts upstream of or within centrosome duplication and embryo development. WB:WBGene00077744 szy-16 Acts upstream of or within centrosome duplication. WB:WBGene00077745 szy-17 Acts upstream of or within centrosome duplication and meiotic chromosome segregation. WB:WBGene00077746 szy-18 Acts upstream of or within cell division and centrosome duplication. WB:WBGene00077747 szy-19 Acts upstream of or within centrosome duplication. WB:WBGene00077750 W01B6.11 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; bortezomib; and Doxycycline based on RNA-seq studies. WB:WBGene00077751 irld-27 Enriched in AUAL; AUAR; MSpaaaaa; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; eat-2; and elt-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00077752 Y105C5A.508 Enriched in Z1; Z4; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. Is affected by four chemicals including allantoin; metformin; and Psoralens based on RNA-seq studies. WB:WBGene00077753 R13.6 Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. WB:WBGene00077754 Y116A8C.199 No description available WB:WBGene00077755 Y40H7A.147 Enriched in intestine based on RNA-seq studies. Is affected by several genes including hsf-1; sir-2.1; and clk-1 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00077756 Y11D7A.19 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalapppaa; ABplppaapa; and PLM based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including 1-methylnicotinamide; mianserin; and multi-walled carbon nanotube based on RNA-seq and microarray studies. WB:WBGene00077757 E02H4.7 Enriched in head mesodermal cell and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on RNA-seq and microarray studies. Is affected by twenty chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. WB:WBGene00077758 irld-12 Enriched in ASJL; ASJR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by etr-1 and hlh-26 based on RNA-seq studies. Is affected by Chlorpyrifos based on microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00077759 irld-51 Enriched in neurons based on RNA-seq studies. Is affected by hpl-2 and csr-1 based on tiling array and RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00077761 zip-9 Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. WB:WBGene00077762 Y57G11C.499 Enriched in germline precursor cell; head mesodermal cell; and intestine based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Alovudine; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00077763 glb-34 Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in BAGL and BAGR. Human ortholog(s) of this gene implicated in COVID-19 and acute kidney failure. Is an ortholog of human CYGB (cytoglobin). WB:WBGene00077764 F59C6.16 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and Caappd based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on RNA-seq and microarray studies. Is affected by nineteen chemicals including 1-methylnicotinamide; rotenone; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00077765 T20F10.8 Is affected by several genes including daf-2; eat-2; and hpl-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00077766 rgba-1 Expressed in cephalic sheath cell; ray; ray structural cell; and socket cell. WB:WBGene00077767 F22D6.17 Is affected by clk-1; daf-16; and daf-2 based on microarray and RNA-seq studies. WB:WBGene00077768 K04G2.12 Predicted to be located in membrane. WB:WBGene00077769 F33E2.10 Enriched in neurons and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-12; and clk-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00077770 M04D5.3 Predicted to be located in membrane. WB:WBGene00077771 tspo-1 Predicted to be located in mitochondrial outer membrane. Is an ortholog of human TSPO (translocator protein). WB:WBGene00077772 T02G6.10 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; multi-walled carbon nanotube; and metformin based on RNA-seq studies. WB:WBGene00077773 F25H5.10 Enriched in PVPL; PVPR; intestine; and posterior arcade cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including eat-2; sir-2.1; and atfs-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including rotenone; stavudine; and Psoralens based on RNA-seq studies. WB:WBGene00077775 nlp-58 Predicted to be involved in neuropeptide signaling pathway. Expressed in chemosensory neurons and ventral ganglion (post). WB:WBGene00077778 dopy-3 No description available WB:WBGene00077779 dopy-5 No description available WB:WBGene00077780 dopy-6 No description available WB:WBGene00077781 F40E3.7 Is affected by several genes including daf-16; hpl-2; and mut-16 based on tiling array and RNA-seq studies. Is affected by Sodium Chloride; Tunicamycin; and paraquat based on RNA-seq and microarray studies. WB:WBGene00077782 T26H10.2 Enriched in neurons and in male based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00077783 D1054.18 Enriched in ADLL; ADLR; and intestine based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by twelve chemicals including rotenone; multi-walled carbon nanotube; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00077784 F35C8.9 Enriched in AVF; AVK; and PVM based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hpl-2; and hda-2 based on RNA-seq and microarray studies. Is affected by cholesterol based on RNA-seq studies. WB:WBGene00077785 F35E2.11 Enriched in male based on RNA-seq studies. Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00077786 F53F8.7 Predicted to be located in membrane. WB:WBGene00077787 T05E12.10 Enriched in NSM and germ line based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and tph-1 based on tiling array; RNA-seq; and microarray studies. Is affected by stavudine; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00077788 W07G4.8 Enriched in neuronal sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; alg-1; and dpy-21 based on RNA-seq and microarray studies. Is affected by Cry5B; Sirolimus; and allantoin based on microarray studies. WB:WBGene00077789 Y26D4A.22 Is affected by daf-2 and smn-1 based on microarray and RNA-seq studies. WB:WBGene00086546 inpp-5K Predicted to enable phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Involved in positive regulation of flagellated sperm motility and regulation of brood size. Located in several cellular components, including neuronal cell body; nucleus; and plasma membrane bounded cell projection. Expressed in PVDL and PVDR. Human ortholog(s) of this gene implicated in congenital muscular dystrophy with cataracts and intellectual disability. Is an ortholog of human INPP5J (inositol polyphosphate-5-phosphatase J) and INPP5K (inositol polyphosphate-5-phosphatase K). WB:WBGene00086547 cil-2 No description available WB:WBGene00086548 cil-3 No description available WB:WBGene00086550 cil-5 No description available WB:WBGene00086551 D2005.7 Enriched in germ line; germline precursor cell; head mesodermal cell; and pharynx based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and clk-1 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including rotenone; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00086552 C17D12.9 Is affected by hpl-2 and dpy-21 based on tiling array and RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00086553 ZC334.13 Enriched in AFD; AWA; AWAL; AWAR; and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including nhr-49; prg-1; and daf-1 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00086554 D1081.12 Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Rap protein signal transduction and negative regulation of cell migration. Predicted to be located in plasma membrane. WB:WBGene00086555 F49B2.7 Enriched in ABalapppaa; body wall muscle cell; intestine; and neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00086556 F36D1.12 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; csr-1; and met-2 based on RNA-seq studies. Is affected by tryptophan based on microarray studies. WB:WBGene00086557 K07A12.8 Predicted to be located in membrane. WB:WBGene00086558 F12E12.12 Enriched in several structures, including RIS; carbon dioxide sensory neurons; excretory system; male distal tip cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including tryptophan; Sodium Chloride; and Rifampin based on microarray and RNA-seq studies. WB:WBGene00086559 Y43F8B.20 Predicted to be located in membrane. WB:WBGene00086560 ZK355.8 Enriched in dopaminergic neurons and intestine based on tiling array studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00086561 K01A2.12 Enriched in DA neuron; GABAergic neurons; VA neuron; and muscle cell based on RNA-seq and microarray studies. Is affected by several genes including daf-16; dpy-10; and gld-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including Cry5B; Oligosaccharides; and Quercetin based on microarray and RNA-seq studies. WB:WBGene00086562 T02G6.11 Enriched in NSM; Z1; and Z4 based on tiling array and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00086563 K08C9.9 Enriched in NSM based on tiling array studies. Is affected by several genes including sir-2.1; clk-1; and dpy-21 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00086564 K08C9.10 Is affected by several genes including let-7; gld-1; and pmt-2 based on proteomic; microarray; and RNA-seq studies. WB:WBGene00086565 W06G6.17 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00086566 C08H9.16 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Is an ortholog of human FRA10AC1 (FRA10A associated CGG repeat 1). WB:WBGene00086567 C05C10.8 Enriched in Caapa; somatic gonad precursor; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; clk-1; and tph-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00086568 Y2H9A.6 Predicted to be located in membrane. WB:WBGene00086569 F38A6.5 Enriched in OLL; PVD; body wall muscle cell; and head mesodermal cell based on tiling array and RNA-seq studies. Is affected by several genes including glp-1; daf-12; and sek-1 based on RNA-seq and proteomic studies. Is affected by eight chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00119201 C08E8.11 Is affected by several genes including eat-2; tph-1; and csr-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00119202 epa-18 No description available WB:WBGene00119203 T04A8.18 Enriched in head mesodermal cell and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; rrf-3; and sek-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box protein she-1-like and F-box domain. WB:WBGene00119204 ZC116.5 Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by six chemicals including rotenone; Sodium Chloride; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00138711 R07B1.13 Enriched in RIA; coelomocyte; hypodermis; and sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and D-glucose based on RNA-seq; microarray; and proteomic studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00138714 T02D1.9 Enriched in AFD and neurons based on RNA-seq and microarray studies. Is affected by csr-1 based on RNA-seq studies. Is affected by dibromoacetic acid based on microarray studies. WB:WBGene00138715 Y6G8.14 Enriched in male based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00138716 F17B5.10 Predicted to be located in membrane. WB:WBGene00138717 F52C12.6 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in tRNA threonylcarbamoyladenosine metabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of EKC/KEOPS complex. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 4. Is an ortholog of human TP53RK (TP53 regulating kinase). WB:WBGene00138719 F26F2.10 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; Cry5B; and glycine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: C6 domain. WB:WBGene00138720 F58H1.8 Predicted to be located in membrane. WB:WBGene00138721 pals-37 Predicted to be involved in positive regulation of cytokinesis. Predicted to be located in centrosome and spindle pole. WB:WBGene00138724 F15B9.11 Enriched in accessory cell and arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and clk-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Tunicamycin; multi-walled carbon nanotube; and Psoralens based on RNA-seq studies. WB:WBGene00164968 K08H2.10 Enriched in ADEshL; ADEshR; G2; W cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including manganese chloride; Alovudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00164969 K09C8.9 Enriched in g1 and neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by 1-methylnicotinamide; cholesterol; and Doxycycline based on RNA-seq studies. WB:WBGene00164971 T21E8.6 Predicted to enable transferase activity. WB:WBGene00164972 T21E8.7 Enriched in RIH based on single-cell RNA-seq studies. Is affected by smg-2 based on RNA-seq studies. Is affected by eight chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00164973 C39B10.7 Predicted to be located in membrane. WB:WBGene00164974 F46C3.7 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABplppppaa; RIM; and interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by Cry5B and silicon dioxide nanoparticle based on microarray studies. WB:WBGene00164983 C36A4.12 Enriched in RIM based on single-cell RNA-seq studies. Is affected by several genes including daf-16; smg-2; and etr-1 based on RNA-seq studies. Is affected by Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00164985 ZK1010.10 Predicted to enable histone acetyltransferase activity and metal ion binding activity. Predicted to be involved in chromatin remodeling and regulation of DNA-templated transcription. Predicted to be located in nucleus. WB:WBGene00164986 Y48A6C.6 Enriched in AFD based on RNA-seq studies. Is affected by several genes including eat-2; alg-1; and dlc-1 based on RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00164989 dopy-4 No description available WB:WBGene00164991 21ur-13442 No description available WB:WBGene00164992 21ur-9698 No description available WB:WBGene00164993 21ur-13666 Enriched in neurons based on RNA-seq studies. WB:WBGene00164994 21ur-9733 No description available WB:WBGene00164995 21ur-15156 No description available WB:WBGene00164996 21ur-13838 No description available WB:WBGene00164997 21ur-10879 No description available WB:WBGene00164998 21ur-10162 No description available WB:WBGene00164999 21ur-8062 No description available WB:WBGene00165000 21ur-10875 No description available WB:WBGene00165001 21ur-8807 No description available WB:WBGene00165002 21ur-13275 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165003 21ur-10772 No description available WB:WBGene00165004 21ur-12132 Enriched in neurons based on RNA-seq studies. WB:WBGene00165005 21ur-12650 No description available WB:WBGene00165006 21ur-10780 No description available WB:WBGene00165007 21ur-5517 No description available WB:WBGene00165009 21ur-11798 No description available WB:WBGene00165010 21ur-6438 No description available WB:WBGene00165011 21ur-14214 No description available WB:WBGene00165012 21ur-13773 No description available WB:WBGene00165013 21ur-14731 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00165014 21ur-13331 No description available WB:WBGene00165015 21ur-12098 No description available WB:WBGene00165016 21ur-14343 No description available WB:WBGene00165017 21ur-5533 Enriched in neurons based on RNA-seq studies. WB:WBGene00165018 21ur-8237 No description available WB:WBGene00165019 21ur-11415 No description available WB:WBGene00165020 21ur-10381 No description available WB:WBGene00165021 21ur-8417 No description available WB:WBGene00165022 21ur-7663 No description available WB:WBGene00165023 21ur-13460 No description available WB:WBGene00165024 21ur-13551 No description available WB:WBGene00165025 21ur-6855 No description available WB:WBGene00165026 21ur-9589 No description available WB:WBGene00165027 21ur-11151 No description available WB:WBGene00165028 21ur-6431 No description available WB:WBGene00165029 21ur-9824 No description available WB:WBGene00165030 21ur-5719 No description available WB:WBGene00165031 21ur-9354 No description available WB:WBGene00165032 21ur-7930 No description available WB:WBGene00165033 21ur-14211 No description available WB:WBGene00165034 21ur-10350 No description available WB:WBGene00165035 21ur-12577 No description available WB:WBGene00165036 21ur-8400 No description available WB:WBGene00165037 21ur-8299 No description available WB:WBGene00165038 21ur-9842 No description available WB:WBGene00165039 21ur-5880 No description available WB:WBGene00165040 21ur-13486 No description available WB:WBGene00165041 21ur-5951 No description available WB:WBGene00165042 21ur-10453 No description available WB:WBGene00165043 21ur-7485 No description available WB:WBGene00165044 21ur-12258 No description available WB:WBGene00165045 21ur-8436 No description available WB:WBGene00165046 21ur-10091 No description available WB:WBGene00165047 21ur-12645 No description available WB:WBGene00165048 21ur-7066 No description available WB:WBGene00165049 21ur-15672 No description available WB:WBGene00165050 21ur-14049 No description available WB:WBGene00165051 21ur-14338 No description available WB:WBGene00165052 21ur-12499 No description available WB:WBGene00165053 21ur-8229 No description available WB:WBGene00165054 21ur-13726 No description available WB:WBGene00165055 21ur-12136 No description available WB:WBGene00165056 21ur-13558 No description available WB:WBGene00165057 21ur-10440 No description available WB:WBGene00165058 21ur-13038 No description available WB:WBGene00165059 21ur-11728 Is affected by set-2 based on RNA-seq studies. WB:WBGene00165060 21ur-14285 No description available WB:WBGene00165061 21ur-8284 No description available WB:WBGene00165062 21ur-8433 No description available WB:WBGene00165063 21ur-14301 No description available WB:WBGene00165064 21ur-12835 No description available WB:WBGene00165065 21ur-10741 No description available WB:WBGene00165066 21ur-7502 No description available WB:WBGene00165067 21ur-10237 No description available WB:WBGene00165068 21ur-9218 No description available WB:WBGene00165069 21ur-8833 No description available WB:WBGene00165070 21ur-12888 No description available WB:WBGene00165071 21ur-6770 No description available WB:WBGene00165072 21ur-7604 No description available WB:WBGene00165073 21ur-8215 No description available WB:WBGene00165074 21ur-7800 No description available WB:WBGene00165075 21ur-13468 Enriched in neurons based on RNA-seq studies. WB:WBGene00165076 21ur-12485 No description available WB:WBGene00165077 21ur-11811 No description available WB:WBGene00165078 21ur-10445 No description available WB:WBGene00165079 21ur-10064 No description available WB:WBGene00165080 21ur-14832 No description available WB:WBGene00165081 21ur-8247 No description available WB:WBGene00165082 21ur-15040 No description available WB:WBGene00165083 21ur-12052 No description available WB:WBGene00165084 21ur-12165 No description available WB:WBGene00165085 21ur-5762 No description available WB:WBGene00165086 21ur-9405 No description available WB:WBGene00165087 21ur-11486 No description available WB:WBGene00165088 21ur-7598 No description available WB:WBGene00165089 21ur-6929 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00165090 21ur-6337 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00165091 21ur-13449 No description available WB:WBGene00165092 21ur-15148 No description available WB:WBGene00165093 21ur-13001 Enriched in neurons based on RNA-seq studies. WB:WBGene00165094 21ur-7868 No description available WB:WBGene00165095 21ur-12977 No description available WB:WBGene00165096 21ur-10593 No description available WB:WBGene00165097 21ur-14473 No description available WB:WBGene00165098 21ur-12443 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00165099 21ur-12966 No description available WB:WBGene00165100 21ur-7671 No description available WB:WBGene00165101 21ur-5834 No description available WB:WBGene00165102 21ur-14042 Enriched in neurons based on RNA-seq studies. WB:WBGene00165103 21ur-6785 No description available WB:WBGene00165104 21ur-14476 No description available WB:WBGene00165105 21ur-6752 No description available WB:WBGene00165106 21ur-12329 No description available WB:WBGene00165107 21ur-9451 No description available WB:WBGene00165108 21ur-7545 No description available WB:WBGene00165109 21ur-14626 No description available WB:WBGene00165110 21ur-9149 No description available WB:WBGene00165111 21ur-8793 No description available WB:WBGene00165112 21ur-14003 No description available WB:WBGene00165113 21ur-7398 No description available WB:WBGene00165114 21ur-6548 No description available WB:WBGene00165115 21ur-9100 No description available WB:WBGene00165116 21ur-10948 No description available WB:WBGene00165117 21ur-12069 No description available WB:WBGene00165118 21ur-6403 No description available WB:WBGene00165119 21ur-15553 No description available WB:WBGene00165120 21ur-8717 No description available WB:WBGene00165121 21ur-9420 No description available WB:WBGene00165122 21ur-7774 No description available WB:WBGene00165123 21ur-10345 No description available WB:WBGene00165124 21ur-9891 No description available WB:WBGene00165125 21ur-14703 No description available WB:WBGene00165126 21ur-12382 No description available WB:WBGene00165127 21ur-5618 No description available WB:WBGene00165128 21ur-7333 No description available WB:WBGene00165129 21ur-8730 No description available WB:WBGene00165130 21ur-14035 No description available WB:WBGene00165131 21ur-14406 No description available WB:WBGene00165132 21ur-6107 No description available WB:WBGene00165133 21ur-12538 Enriched in neurons based on RNA-seq studies. WB:WBGene00165134 21ur-11762 No description available WB:WBGene00165135 21ur-10836 No description available WB:WBGene00165136 21ur-8989 No description available WB:WBGene00165137 21ur-15419 No description available WB:WBGene00165138 21ur-15309 No description available WB:WBGene00165139 21ur-14007 No description available WB:WBGene00165140 21ur-13810 No description available WB:WBGene00165141 21ur-15469 No description available WB:WBGene00165142 21ur-12723 No description available WB:WBGene00165143 21ur-10734 No description available WB:WBGene00165144 21ur-6139 No description available WB:WBGene00165146 21ur-7805 No description available WB:WBGene00165147 21ur-7541 Enriched in neurons based on RNA-seq studies. WB:WBGene00165148 21ur-14066 No description available WB:WBGene00165149 21ur-7918 No description available WB:WBGene00165150 21ur-11855 No description available WB:WBGene00165151 21ur-11959 No description available WB:WBGene00165152 21ur-11831 No description available WB:WBGene00165153 21ur-7474 No description available WB:WBGene00165154 21ur-10467 No description available WB:WBGene00165155 21ur-7853 No description available WB:WBGene00165156 21ur-10787 No description available WB:WBGene00165157 21ur-8479 No description available WB:WBGene00165158 21ur-13225 No description available WB:WBGene00165159 21ur-10840 No description available WB:WBGene00165160 21ur-12458 No description available WB:WBGene00165161 21ur-6421 No description available WB:WBGene00165162 21ur-5944 No description available WB:WBGene00165163 21ur-7229 No description available WB:WBGene00165164 21ur-7751 No description available WB:WBGene00165165 21ur-5959 No description available WB:WBGene00165166 21ur-15701 Is affected by spr-5 based on RNA-seq studies. WB:WBGene00165167 21ur-11339 No description available WB:WBGene00165168 21ur-7910 No description available WB:WBGene00165169 21ur-10193 No description available WB:WBGene00165170 21ur-13231 No description available WB:WBGene00165171 21ur-14370 No description available WB:WBGene00165172 21ur-11737 Enriched in neurons based on RNA-seq studies. Is affected by set-2 and met-2 based on RNA-seq studies. WB:WBGene00165173 21ur-5899 No description available WB:WBGene00165174 21ur-5829 No description available WB:WBGene00165175 21ur-5669 No description available WB:WBGene00165176 21ur-15245 No description available WB:WBGene00165177 21ur-13152 No description available WB:WBGene00165178 21ur-12260 No description available WB:WBGene00165179 21ur-11789 No description available WB:WBGene00165180 21ur-12855 No description available WB:WBGene00165181 21ur-6028 No description available WB:WBGene00165182 21ur-12768 No description available WB:WBGene00165183 21ur-8122 No description available WB:WBGene00165184 21ur-14880 No description available WB:WBGene00165185 21ur-6706 No description available WB:WBGene00165186 21ur-14530 No description available WB:WBGene00165187 21ur-13308 No description available WB:WBGene00165188 21ur-13392 No description available WB:WBGene00165189 21ur-10414 No description available WB:WBGene00165190 21ur-12332 No description available WB:WBGene00165191 21ur-14892 No description available WB:WBGene00165192 21ur-12224 No description available WB:WBGene00165193 21ur-12007 No description available WB:WBGene00165194 21ur-15624 No description available WB:WBGene00165195 21ur-13923 No description available WB:WBGene00165196 21ur-12876 No description available WB:WBGene00165197 21ur-8558 No description available WB:WBGene00165198 21ur-10728 No description available WB:WBGene00165199 21ur-6698 No description available WB:WBGene00165200 21ur-12716 No description available WB:WBGene00165201 21ur-7232 No description available WB:WBGene00165202 21ur-12013 No description available WB:WBGene00165203 21ur-7204 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00165204 21ur-8509 No description available WB:WBGene00165205 21ur-15215 No description available WB:WBGene00165206 21ur-9430 No description available WB:WBGene00165207 21ur-10846 No description available WB:WBGene00165208 21ur-13738 No description available WB:WBGene00165209 21ur-6522 No description available WB:WBGene00165210 21ur-13044 No description available WB:WBGene00165211 21ur-10657 Is affected by daf-2 based on microarray studies. WB:WBGene00165212 21ur-13281 No description available WB:WBGene00165213 21ur-15590 No description available WB:WBGene00165214 21ur-10718 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165215 21ur-14925 No description available WB:WBGene00165217 21ur-6205 No description available WB:WBGene00165218 21ur-15086 No description available WB:WBGene00165219 21ur-8129 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165220 21ur-14461 No description available WB:WBGene00165221 21ur-7480 No description available WB:WBGene00165222 21ur-14927 No description available WB:WBGene00165223 21ur-8652 No description available WB:WBGene00165224 21ur-6912 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165225 21ur-12619 No description available WB:WBGene00165226 21ur-8489 No description available WB:WBGene00165227 21ur-5892 No description available WB:WBGene00165228 21ur-6794 No description available WB:WBGene00165229 21ur-11607 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00165230 21ur-6866 No description available WB:WBGene00165231 21ur-5488 No description available WB:WBGene00165232 21ur-7987 No description available WB:WBGene00165233 21ur-12981 No description available WB:WBGene00165234 21ur-11923 No description available WB:WBGene00165235 21ur-7717 Is affected by smn-1 based on RNA-seq studies. WB:WBGene00165236 21ur-5496 No description available WB:WBGene00165237 21ur-11584 No description available WB:WBGene00165238 21ur-7886 No description available WB:WBGene00165239 21ur-6114 No description available WB:WBGene00165240 21ur-10729 No description available WB:WBGene00165241 21ur-14394 No description available WB:WBGene00165242 21ur-7166 No description available WB:WBGene00165243 21ur-12155 No description available WB:WBGene00165244 21ur-10391 Enriched in neurons based on RNA-seq studies. WB:WBGene00165245 21ur-12583 No description available WB:WBGene00165246 21ur-10921 No description available WB:WBGene00165247 21ur-13435 No description available WB:WBGene00165248 21ur-5925 No description available WB:WBGene00165249 21ur-9503 Enriched in neurons based on RNA-seq studies. WB:WBGene00165250 21ur-13051 No description available WB:WBGene00165251 21ur-11648 Enriched in neurons based on RNA-seq studies. WB:WBGene00165252 21ur-6922 No description available WB:WBGene00165253 21ur-13086 No description available WB:WBGene00165254 21ur-6919 No description available WB:WBGene00165255 21ur-13765 No description available WB:WBGene00165256 21ur-6570 No description available WB:WBGene00165257 21ur-13292 Enriched in neurons based on RNA-seq studies. WB:WBGene00165258 21ur-7249 No description available WB:WBGene00165259 21ur-13328 No description available WB:WBGene00165260 21ur-5814 No description available WB:WBGene00165261 21ur-14963 No description available WB:WBGene00165262 21ur-14204 No description available WB:WBGene00165263 21ur-5525 No description available WB:WBGene00165264 21ur-6811 No description available WB:WBGene00165265 21ur-10823 No description available WB:WBGene00165266 21ur-9163 No description available WB:WBGene00165267 21ur-8461 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00165268 21ur-6686 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00165269 21ur-7927 Enriched in neurons based on RNA-seq studies. WB:WBGene00165270 21ur-10419 No description available WB:WBGene00165271 21ur-12087 No description available WB:WBGene00165272 21ur-14728 No description available WB:WBGene00165273 21ur-14428 No description available WB:WBGene00165274 21ur-14769 No description available WB:WBGene00165275 21ur-6720 No description available WB:WBGene00165276 21ur-13324 No description available WB:WBGene00165277 21ur-8198 No description available WB:WBGene00165278 21ur-5818 No description available WB:WBGene00165279 21ur-15533 No description available WB:WBGene00165280 21ur-8625 No description available WB:WBGene00165281 21ur-14014 No description available WB:WBGene00165282 21ur-12938 No description available WB:WBGene00165283 21ur-8001 No description available WB:WBGene00165284 21ur-11829 Enriched in neurons based on RNA-seq studies. WB:WBGene00165285 21ur-11310 No description available WB:WBGene00165286 21ur-10280 No description available WB:WBGene00165287 21ur-10694 No description available WB:WBGene00165288 21ur-14889 No description available WB:WBGene00165289 21ur-6768 No description available WB:WBGene00165290 21ur-6328 No description available WB:WBGene00165291 21ur-5749 No description available WB:WBGene00165292 21ur-5858 No description available WB:WBGene00165293 21ur-8510 No description available WB:WBGene00165294 21ur-12659 No description available WB:WBGene00165295 21ur-6843 No description available WB:WBGene00165296 21ur-6378 No description available WB:WBGene00165297 21ur-8407 No description available WB:WBGene00165298 21ur-8323 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00165299 21ur-11421 No description available WB:WBGene00165300 21ur-11950 No description available WB:WBGene00165301 21ur-14327 No description available WB:WBGene00165302 21ur-13790 No description available WB:WBGene00165303 21ur-13651 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00165304 21ur-7566 No description available WB:WBGene00165305 21ur-15424 No description available WB:WBGene00165306 21ur-15026 No description available WB:WBGene00165307 21ur-10188 No description available WB:WBGene00165308 21ur-9080 No description available WB:WBGene00165309 21ur-15274 No description available WB:WBGene00165310 21ur-9910 No description available WB:WBGene00165311 21ur-10537 No description available WB:WBGene00165312 21ur-11233 Enriched in neurons based on RNA-seq studies. WB:WBGene00165313 21ur-13998 No description available WB:WBGene00165314 21ur-5878 No description available WB:WBGene00165315 21ur-10769 No description available WB:WBGene00165316 21ur-9492 No description available WB:WBGene00165317 21ur-10127 No description available WB:WBGene00165318 21ur-13193 No description available WB:WBGene00165319 21ur-8046 No description available WB:WBGene00165320 21ur-6495 No description available WB:WBGene00165321 21ur-7456 No description available WB:WBGene00165322 21ur-15621 No description available WB:WBGene00165323 21ur-9672 No description available WB:WBGene00165324 21ur-11084 No description available WB:WBGene00165325 21ur-9730 No description available WB:WBGene00165326 21ur-15166 No description available WB:WBGene00165327 21ur-13304 No description available WB:WBGene00165328 21ur-13126 No description available WB:WBGene00165329 21ur-9701 No description available WB:WBGene00165330 21ur-7348 No description available WB:WBGene00165331 21ur-12117 Is affected by eat-2 based on microarray studies. WB:WBGene00165332 21ur-9836 Enriched in RID based on RNA-seq studies. Is affected by unc-39 and set-2 based on RNA-seq studies. WB:WBGene00165333 21ur-12958 No description available WB:WBGene00165334 21ur-12480 No description available WB:WBGene00165335 21ur-13713 No description available WB:WBGene00165336 21ur-10554 No description available WB:WBGene00165337 21ur-13970 No description available WB:WBGene00165338 21ur-14680 No description available WB:WBGene00165339 21ur-12918 No description available WB:WBGene00165340 21ur-12953 No description available WB:WBGene00165341 21ur-5773 No description available WB:WBGene00165342 21ur-12113 No description available WB:WBGene00165343 21ur-10795 No description available WB:WBGene00165344 21ur-10433 No description available WB:WBGene00165345 21ur-10576 No description available WB:WBGene00165346 21ur-14363 No description available WB:WBGene00165347 21ur-6287 Enriched in neurons based on RNA-seq studies. WB:WBGene00165348 21ur-6952 No description available WB:WBGene00165349 21ur-6541 No description available WB:WBGene00165350 21ur-8660 No description available WB:WBGene00165351 21ur-7185 No description available WB:WBGene00165352 21ur-12711 No description available WB:WBGene00165353 21ur-11697 No description available WB:WBGene00165354 21ur-11144 No description available WB:WBGene00165355 21ur-6124 No description available WB:WBGene00165356 21ur-15630 Is affected by several genes including hpl-2; meg-3; and olrn-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00165357 21ur-14095 No description available WB:WBGene00165358 21ur-8314 No description available WB:WBGene00165359 21ur-6321 No description available WB:WBGene00165360 21ur-12413 No description available WB:WBGene00165361 21ur-7124 No description available WB:WBGene00165362 21ur-12343 No description available WB:WBGene00165363 21ur-6501 No description available WB:WBGene00165364 21ur-8113 No description available WB:WBGene00165365 21ur-10756 No description available WB:WBGene00165366 21ur-13039 No description available WB:WBGene00165367 21ur-12513 No description available WB:WBGene00165368 21ur-6931 No description available WB:WBGene00165369 21ur-13340 No description available WB:WBGene00165370 21ur-8727 Enriched in neurons based on RNA-seq studies. WB:WBGene00165371 21ur-11471 No description available WB:WBGene00165372 21ur-10256 No description available WB:WBGene00165373 21ur-9312 No description available WB:WBGene00165374 21ur-14970 No description available WB:WBGene00165375 21ur-5648 No description available WB:WBGene00165376 21ur-11903 No description available WB:WBGene00165377 21ur-6178 No description available WB:WBGene00165378 21ur-11769 No description available WB:WBGene00165379 21ur-6198 No description available WB:WBGene00165380 21ur-10022 No description available WB:WBGene00165381 21ur-9649 No description available WB:WBGene00165382 21ur-14856 No description available WB:WBGene00165383 21ur-11991 No description available WB:WBGene00165384 21ur-6454 No description available WB:WBGene00165385 21ur-12515 No description available WB:WBGene00165386 21ur-8505 No description available WB:WBGene00165387 21ur-6663 No description available WB:WBGene00165388 21ur-11177 No description available WB:WBGene00165389 21ur-10293 No description available WB:WBGene00165390 21ur-9383 No description available WB:WBGene00165391 21ur-15402 No description available WB:WBGene00165392 21ur-9930 No description available WB:WBGene00165393 21ur-6732 No description available WB:WBGene00165394 21ur-6606 No description available WB:WBGene00165395 21ur-10038 No description available WB:WBGene00165396 21ur-7188 Enriched in neurons based on RNA-seq studies. WB:WBGene00165397 21ur-10631 No description available WB:WBGene00165398 21ur-8979 No description available WB:WBGene00165399 21ur-9565 Enriched in neurons based on RNA-seq studies. WB:WBGene00165400 21ur-13927 No description available WB:WBGene00165401 21ur-12891 No description available WB:WBGene00165402 21ur-12460 No description available WB:WBGene00165403 21ur-11507 No description available WB:WBGene00165404 21ur-8963 Enriched in neurons based on RNA-seq studies. WB:WBGene00165405 21ur-10634 No description available WB:WBGene00165406 21ur-10862 Enriched in neurons based on RNA-seq studies. WB:WBGene00165407 21ur-9346 No description available WB:WBGene00165408 21ur-13150 No description available WB:WBGene00165409 21ur-14236 No description available WB:WBGene00165410 21ur-6371 No description available WB:WBGene00165411 21ur-13957 No description available WB:WBGene00165412 21ur-6100 No description available WB:WBGene00165413 21ur-9784 No description available WB:WBGene00165414 21ur-5885 No description available WB:WBGene00165415 21ur-13012 No description available WB:WBGene00165416 21ur-9940 No description available WB:WBGene00165417 21ur-12472 No description available WB:WBGene00165418 21ur-8278 No description available WB:WBGene00165419 21ur-13968 No description available WB:WBGene00165420 21ur-11300 No description available WB:WBGene00165421 21ur-9371 No description available WB:WBGene00165422 21ur-6991 No description available WB:WBGene00165423 21ur-14154 No description available WB:WBGene00165424 21ur-12148 No description available WB:WBGene00165425 21ur-6992 No description available WB:WBGene00165426 21ur-8529 No description available WB:WBGene00165427 21ur-7519 No description available WB:WBGene00165428 21ur-15149 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00165429 21ur-14434 No description available WB:WBGene00165430 21ur-10119 No description available WB:WBGene00165431 21ur-9902 No description available WB:WBGene00165432 21ur-14368 No description available WB:WBGene00165433 21ur-5523 No description available WB:WBGene00165434 21ur-13984 No description available WB:WBGene00165435 21ur-11701 No description available WB:WBGene00165436 21ur-9617 No description available WB:WBGene00165438 21ur-7562 No description available WB:WBGene00165439 21ur-14742 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165440 21ur-14638 No description available WB:WBGene00165441 21ur-11468 No description available WB:WBGene00165442 21ur-11196 No description available WB:WBGene00165443 21ur-15495 No description available WB:WBGene00165444 21ur-14554 No description available WB:WBGene00165445 21ur-15647 No description available WB:WBGene00165446 21ur-6576 No description available WB:WBGene00165447 21ur-15293 No description available WB:WBGene00165448 21ur-12709 No description available WB:WBGene00165449 21ur-6483 No description available WB:WBGene00165450 21ur-6008 Enriched in neurons based on RNA-seq studies. WB:WBGene00165451 21ur-12529 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00165452 21ur-11374 Enriched in neurons based on RNA-seq studies. WB:WBGene00165453 21ur-7539 No description available WB:WBGene00165454 21ur-7099 Enriched in neurons based on RNA-seq studies. WB:WBGene00165455 21ur-8683 Enriched in neurons based on RNA-seq studies. WB:WBGene00165456 21ur-8258 No description available WB:WBGene00165457 21ur-13793 No description available WB:WBGene00165458 21ur-11409 No description available WB:WBGene00165459 21ur-14260 No description available WB:WBGene00165460 21ur-7220 No description available WB:WBGene00165461 21ur-13676 No description available WB:WBGene00165462 21ur-10595 No description available WB:WBGene00165463 21ur-7961 No description available WB:WBGene00165464 21ur-6200 No description available WB:WBGene00165465 21ur-9917 No description available WB:WBGene00165466 21ur-14420 No description available WB:WBGene00165467 21ur-12490 No description available WB:WBGene00165468 21ur-9547 No description available WB:WBGene00165469 21ur-7224 No description available WB:WBGene00165470 21ur-8410 No description available WB:WBGene00165471 21ur-7243 No description available WB:WBGene00165472 21ur-9580 No description available WB:WBGene00165473 21ur-14436 No description available WB:WBGene00165474 21ur-10171 No description available WB:WBGene00165475 21ur-8022 No description available WB:WBGene00165476 21ur-7268 Enriched in neurons based on RNA-seq studies. WB:WBGene00165477 21ur-9079 Enriched in neurons based on RNA-seq studies. WB:WBGene00165478 21ur-14751 No description available WB:WBGene00165479 21ur-5998 No description available WB:WBGene00165480 21ur-15151 No description available WB:WBGene00165481 21ur-9937 No description available WB:WBGene00165482 21ur-5906 No description available WB:WBGene00165483 21ur-15102 Enriched in neurons based on RNA-seq studies. WB:WBGene00165484 21ur-8205 No description available WB:WBGene00165485 21ur-13617 No description available WB:WBGene00165486 21ur-9052 No description available WB:WBGene00165487 21ur-7847 No description available WB:WBGene00165488 21ur-9986 No description available WB:WBGene00165489 21ur-7813 No description available WB:WBGene00165490 21ur-12551 No description available WB:WBGene00165491 21ur-9110 No description available WB:WBGene00165492 21ur-10995 No description available WB:WBGene00165493 21ur-8134 No description available WB:WBGene00165494 21ur-14083 No description available WB:WBGene00165495 21ur-14641 No description available WB:WBGene00165496 21ur-15349 No description available WB:WBGene00165497 21ur-7295 No description available WB:WBGene00165498 21ur-12812 Enriched in neurons based on RNA-seq studies. WB:WBGene00165499 21ur-14985 No description available WB:WBGene00165500 21ur-12341 No description available WB:WBGene00165501 21ur-7694 No description available WB:WBGene00165502 21ur-7609 No description available WB:WBGene00165503 21ur-15679 No description available WB:WBGene00165504 21ur-13179 No description available WB:WBGene00165505 21ur-8909 No description available WB:WBGene00165506 21ur-6225 No description available WB:WBGene00165507 21ur-13094 No description available WB:WBGene00165508 21ur-10220 No description available WB:WBGene00165509 21ur-10108 Enriched in neurons based on RNA-seq studies. WB:WBGene00165510 21ur-8047 No description available WB:WBGene00165511 21ur-15613 No description available WB:WBGene00165512 21ur-13930 No description available WB:WBGene00165513 21ur-6535 No description available WB:WBGene00165514 21ur-13843 No description available WB:WBGene00165515 21ur-11062 No description available WB:WBGene00165516 21ur-9888 No description available WB:WBGene00165517 21ur-9748 No description available WB:WBGene00165518 21ur-8050 No description available WB:WBGene00165519 21ur-12328 No description available WB:WBGene00165520 21ur-6820 No description available WB:WBGene00165521 21ur-11110 No description available WB:WBGene00165522 21ur-12931 No description available WB:WBGene00165523 21ur-7686 No description available WB:WBGene00165524 21ur-5475 No description available WB:WBGene00165525 21ur-8772 No description available WB:WBGene00165526 21ur-10960 No description available WB:WBGene00165527 21ur-8169 No description available WB:WBGene00165528 21ur-10993 No description available WB:WBGene00165529 21ur-10336 No description available WB:WBGene00165530 21ur-15376 No description available WB:WBGene00165531 21ur-7156 Enriched in neurons based on RNA-seq studies. WB:WBGene00165532 21ur-12754 No description available WB:WBGene00165533 21ur-8477 No description available WB:WBGene00165534 21ur-9814 Enriched in neurons based on RNA-seq studies. WB:WBGene00165535 21ur-7933 No description available WB:WBGene00165536 21ur-12864 No description available WB:WBGene00165537 21ur-11575 Is affected by meg-3 and meg-4 based on RNA-seq studies. WB:WBGene00165538 21ur-15382 No description available WB:WBGene00165539 21ur-14243 No description available WB:WBGene00165540 21ur-8098 No description available WB:WBGene00165541 21ur-15354 No description available WB:WBGene00165542 21ur-7094 Enriched in neurons based on RNA-seq studies. WB:WBGene00165543 21ur-14612 No description available WB:WBGene00165544 21ur-6716 No description available WB:WBGene00165545 21ur-6087 No description available WB:WBGene00165546 21ur-8852 No description available WB:WBGene00165547 21ur-9177 No description available WB:WBGene00165548 21ur-6309 No description available WB:WBGene00165549 21ur-10033 No description available WB:WBGene00165550 21ur-6243 No description available WB:WBGene00165551 21ur-8577 No description available WB:WBGene00165552 21ur-8773 No description available WB:WBGene00165553 21ur-13788 No description available WB:WBGene00165554 21ur-10353 No description available WB:WBGene00165555 21ur-7957 No description available WB:WBGene00165556 21ur-13760 No description available WB:WBGene00165557 21ur-10667 No description available WB:WBGene00165558 21ur-12468 No description available WB:WBGene00165559 21ur-5728 No description available WB:WBGene00165560 21ur-12685 No description available WB:WBGene00165561 21ur-7341 No description available WB:WBGene00165562 21ur-11075 No description available WB:WBGene00165563 21ur-9741 No description available WB:WBGene00165564 21ur-15688 No description available WB:WBGene00165565 21ur-13202 No description available WB:WBGene00165566 21ur-6171 No description available WB:WBGene00165567 21ur-14839 No description available WB:WBGene00165568 21ur-12522 No description available WB:WBGene00165569 21ur-10815 No description available WB:WBGene00165570 21ur-12080 No description available WB:WBGene00165571 21ur-10200 No description available WB:WBGene00165572 21ur-11768 No description available WB:WBGene00165573 21ur-8029 No description available WB:WBGene00165574 21ur-11844 Enriched in neurons based on RNA-seq studies. WB:WBGene00165575 21ur-7394 No description available WB:WBGene00165576 21ur-14683 No description available WB:WBGene00165577 21ur-13691 No description available WB:WBGene00165578 21ur-9849 No description available WB:WBGene00165579 21ur-8273 No description available WB:WBGene00165580 21ur-7045 No description available WB:WBGene00165581 21ur-8352 No description available WB:WBGene00165582 21ur-8080 No description available WB:WBGene00165583 21ur-11820 No description available WB:WBGene00165584 21ur-11937 No description available WB:WBGene00165585 21ur-8443 No description available WB:WBGene00165586 21ur-15526 No description available WB:WBGene00165587 21ur-11246 No description available WB:WBGene00165588 21ur-6972 Is affected by daf-2 based on microarray studies. WB:WBGene00165589 21ur-11746 Enriched in neurons based on RNA-seq studies. WB:WBGene00165590 21ur-11989 No description available WB:WBGene00165591 21ur-10584 No description available WB:WBGene00165592 21ur-13527 No description available WB:WBGene00165593 21ur-9243 No description available WB:WBGene00165594 21ur-8054 Enriched in neurons based on RNA-seq studies. WB:WBGene00165595 21ur-8934 No description available WB:WBGene00165596 21ur-14818 No description available WB:WBGene00165597 21ur-10055 No description available WB:WBGene00165598 21ur-14548 No description available WB:WBGene00165599 21ur-9367 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165600 21ur-10120 No description available WB:WBGene00165601 21ur-14793 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00165602 21ur-13185 No description available WB:WBGene00165603 21ur-6947 No description available WB:WBGene00165604 21ur-14174 No description available WB:WBGene00165605 21ur-8302 No description available WB:WBGene00165606 21ur-14605 No description available WB:WBGene00165607 21ur-10935 No description available WB:WBGene00165608 21ur-15584 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00165609 21ur-9489 No description available WB:WBGene00165610 21ur-6080 No description available WB:WBGene00165611 21ur-15473 No description available WB:WBGene00165612 21ur-8613 No description available WB:WBGene00165613 21ur-14173 No description available WB:WBGene00165614 21ur-12704 No description available WB:WBGene00165615 21ur-14142 No description available WB:WBGene00165616 21ur-12046 No description available WB:WBGene00165617 21ur-10701 No description available WB:WBGene00165618 21ur-8639 No description available WB:WBGene00165619 21ur-11569 No description available WB:WBGene00165620 21ur-12244 No description available WB:WBGene00165621 21ur-11224 No description available WB:WBGene00165622 21ur-14192 No description available WB:WBGene00165623 21ur-9632 No description available WB:WBGene00165624 21ur-8591 No description available WB:WBGene00165625 21ur-15303 No description available WB:WBGene00165626 21ur-13402 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00165627 21ur-13519 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165628 21ur-15568 No description available WB:WBGene00165629 21ur-9871 No description available WB:WBGene00165630 21ur-6417 No description available WB:WBGene00165631 21ur-8869 No description available WB:WBGene00165632 21ur-8032 No description available WB:WBGene00165633 21ur-13615 No description available WB:WBGene00165634 21ur-10989 No description available WB:WBGene00165635 21ur-10626 No description available WB:WBGene00165636 21ur-9004 No description available WB:WBGene00165637 21ur-8223 No description available WB:WBGene00165638 21ur-7697 No description available WB:WBGene00165639 21ur-13826 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00165640 21ur-6474 No description available WB:WBGene00165641 21ur-15014 No description available WB:WBGene00165642 21ur-11037 No description available WB:WBGene00165643 21ur-8347 No description available WB:WBGene00165644 21ur-10081 No description available WB:WBGene00165645 21ur-13712 No description available WB:WBGene00165646 21ur-9702 No description available WB:WBGene00165647 21ur-14517 No description available WB:WBGene00165648 21ur-8020 No description available WB:WBGene00165649 21ur-13576 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00165650 21ur-8840 No description available WB:WBGene00165651 21ur-5733 No description available WB:WBGene00165652 21ur-6899 No description available WB:WBGene00165653 21ur-10687 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00165654 21ur-8764 No description available WB:WBGene00165655 21ur-7998 No description available WB:WBGene00165656 21ur-7618 No description available WB:WBGene00165657 21ur-11175 No description available WB:WBGene00165658 21ur-14840 No description available WB:WBGene00165659 21ur-9270 No description available WB:WBGene00165660 21ur-11316 No description available WB:WBGene00165661 21ur-13474 No description available WB:WBGene00165662 21ur-12661 No description available WB:WBGene00165663 21ur-11014 No description available WB:WBGene00165664 21ur-8570 No description available WB:WBGene00165665 21ur-13707 No description available WB:WBGene00165666 21ur-6281 Is affected by set-2 based on RNA-seq studies. WB:WBGene00165667 21ur-13454 No description available WB:WBGene00165668 21ur-13136 No description available WB:WBGene00165669 21ur-9132 No description available WB:WBGene00165670 21ur-9182 No description available WB:WBGene00165671 21ur-14520 No description available WB:WBGene00165672 21ur-9679 No description available WB:WBGene00165673 21ur-13900 No description available WB:WBGene00165674 21ur-13868 No description available WB:WBGene00165675 21ur-15199 No description available WB:WBGene00165676 21ur-13266 No description available WB:WBGene00165677 21ur-11291 No description available WB:WBGene00165678 21ur-14266 No description available WB:WBGene00165679 21ur-9408 No description available WB:WBGene00165680 21ur-10782 No description available WB:WBGene00165681 21ur-8914 Is affected by glycine based on RNA-seq studies. WB:WBGene00165682 21ur-11901 No description available WB:WBGene00165683 21ur-6056 No description available WB:WBGene00165684 21ur-14676 No description available WB:WBGene00165685 21ur-9479 No description available WB:WBGene00165686 21ur-6156 No description available WB:WBGene00165687 21ur-13121 Enriched in neurons based on RNA-seq studies. WB:WBGene00165688 21ur-12964 No description available WB:WBGene00165689 21ur-10868 No description available WB:WBGene00165690 21ur-8056 Enriched in neurons based on RNA-seq studies. WB:WBGene00165691 21ur-15466 No description available WB:WBGene00165692 21ur-12894 No description available WB:WBGene00165693 21ur-12524 No description available WB:WBGene00165694 21ur-12392 No description available WB:WBGene00165695 21ur-6980 No description available WB:WBGene00165696 21ur-6301 No description available WB:WBGene00165697 21ur-13643 No description available WB:WBGene00165698 21ur-9721 No description available WB:WBGene00165699 21ur-13495 No description available WB:WBGene00165700 21ur-10275 No description available WB:WBGene00165701 21ur-8755 No description available WB:WBGene00165702 21ur-14869 No description available WB:WBGene00165703 21ur-10561 No description available WB:WBGene00165704 21ur-9652 No description available WB:WBGene00165705 21ur-7351 No description available WB:WBGene00165706 21ur-8695 No description available WB:WBGene00165707 21ur-8066 Enriched in neurons based on RNA-seq studies. WB:WBGene00165708 21ur-15056 No description available WB:WBGene00165709 21ur-10789 No description available WB:WBGene00165710 21ur-10931 No description available WB:WBGene00165711 21ur-10009 No description available WB:WBGene00165712 21ur-14103 No description available WB:WBGene00165713 21ur-6026 No description available WB:WBGene00165714 21ur-15364 No description available WB:WBGene00165715 21ur-10813 No description available WB:WBGene00165716 21ur-8309 No description available WB:WBGene00165717 21ur-14486 No description available WB:WBGene00165718 21ur-9329 No description available WB:WBGene00165719 21ur-6241 No description available WB:WBGene00165720 21ur-8932 No description available WB:WBGene00165721 21ur-7126 No description available WB:WBGene00165722 21ur-7439 No description available WB:WBGene00165723 21ur-11736 No description available WB:WBGene00165724 21ur-9394 No description available WB:WBGene00165725 21ur-13062 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165726 21ur-8027 No description available WB:WBGene00165727 21ur-7572 Enriched in neurons based on RNA-seq studies. WB:WBGene00165728 21ur-5581 No description available WB:WBGene00165729 21ur-9490 No description available WB:WBGene00165730 21ur-8787 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00165731 21ur-14253 No description available WB:WBGene00165732 21ur-11759 No description available WB:WBGene00165733 21ur-9436 No description available WB:WBGene00165734 21ur-9336 No description available WB:WBGene00165735 21ur-6285 No description available WB:WBGene00165736 21ur-12182 No description available WB:WBGene00165737 21ur-12421 No description available WB:WBGene00165738 21ur-7199 No description available WB:WBGene00165739 21ur-5915 No description available WB:WBGene00165740 21ur-15294 No description available WB:WBGene00165741 21ur-14328 No description available WB:WBGene00165742 21ur-9764 No description available WB:WBGene00165743 21ur-6102 No description available WB:WBGene00165744 21ur-11349 No description available WB:WBGene00165745 21ur-6650 No description available WB:WBGene00165746 21ur-14283 No description available WB:WBGene00165747 21ur-11774 No description available WB:WBGene00165748 21ur-10380 No description available WB:WBGene00165749 21ur-8569 No description available WB:WBGene00165750 21ur-15543 No description available WB:WBGene00165751 21ur-6031 No description available WB:WBGene00165752 21ur-11026 No description available WB:WBGene00165753 21ur-10523 No description available WB:WBGene00165754 21ur-10844 No description available WB:WBGene00165755 21ur-8688 No description available WB:WBGene00165756 21ur-15514 No description available WB:WBGene00165757 21ur-11592 No description available WB:WBGene00165758 21ur-12025 No description available WB:WBGene00165759 21ur-6341 No description available WB:WBGene00165760 21ur-14077 No description available WB:WBGene00165761 21ur-14722 No description available WB:WBGene00165762 21ur-12642 No description available WB:WBGene00165763 21ur-9105 No description available WB:WBGene00165764 21ur-7799 No description available WB:WBGene00165765 21ur-9298 No description available WB:WBGene00165766 21ur-13408 No description available WB:WBGene00165767 21ur-6352 No description available WB:WBGene00165768 21ur-7173 No description available WB:WBGene00165769 21ur-7311 Enriched in neurons based on RNA-seq studies. WB:WBGene00165770 21ur-9033 No description available WB:WBGene00165771 21ur-11255 Is affected by meg-3 and meg-4 based on RNA-seq studies. WB:WBGene00165772 21ur-8243 No description available WB:WBGene00165773 21ur-8942 No description available WB:WBGene00165774 21ur-6640 No description available WB:WBGene00165775 21ur-6111 No description available WB:WBGene00165776 21ur-11536 No description available WB:WBGene00165777 21ur-9240 No description available WB:WBGene00165778 21ur-12702 No description available WB:WBGene00165779 21ur-8768 No description available WB:WBGene00165780 21ur-9976 No description available WB:WBGene00165781 21ur-10825 No description available WB:WBGene00165782 21ur-12242 No description available WB:WBGene00165783 21ur-12037 No description available WB:WBGene00165784 21ur-7700 No description available WB:WBGene00165785 21ur-14711 No description available WB:WBGene00165786 21ur-9906 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00165787 21ur-11244 No description available WB:WBGene00165788 21ur-9411 No description available WB:WBGene00165789 21ur-13128 Enriched in neurons based on RNA-seq studies. WB:WBGene00165790 21ur-7329 No description available WB:WBGene00165791 21ur-13369 No description available WB:WBGene00165792 21ur-15184 No description available WB:WBGene00165793 21ur-11285 No description available WB:WBGene00165794 21ur-9460 No description available WB:WBGene00165795 21ur-5546 No description available WB:WBGene00165796 21ur-9301 No description available WB:WBGene00165797 21ur-11260 No description available WB:WBGene00165798 21ur-8560 No description available WB:WBGene00165799 21ur-7584 No description available WB:WBGene00165800 21ur-5787 No description available WB:WBGene00165801 21ur-8076 No description available WB:WBGene00165802 21ur-9919 No description available WB:WBGene00165803 21ur-9264 No description available WB:WBGene00165804 21ur-10000 No description available WB:WBGene00165805 21ur-9066 No description available WB:WBGene00165806 21ur-10287 No description available WB:WBGene00165807 21ur-10322 No description available WB:WBGene00165808 21ur-10264 No description available WB:WBGene00165809 21ur-6122 No description available WB:WBGene00165810 21ur-11805 No description available WB:WBGene00165811 21ur-10011 Enriched in neurons based on RNA-seq studies. WB:WBGene00165812 21ur-14911 No description available WB:WBGene00165813 21ur-11121 No description available WB:WBGene00165814 21ur-8602 No description available WB:WBGene00165815 21ur-8867 Is affected by daf-2 based on microarray studies. WB:WBGene00165816 21ur-14228 No description available WB:WBGene00165817 21ur-15643 No description available WB:WBGene00165818 21ur-11542 No description available WB:WBGene00165819 21ur-10101 No description available WB:WBGene00165820 21ur-15595 No description available WB:WBGene00165821 21ur-9537 No description available WB:WBGene00165822 21ur-12023 No description available WB:WBGene00165823 21ur-8890 No description available WB:WBGene00165824 21ur-11279 No description available WB:WBGene00165825 21ur-7013 No description available WB:WBGene00165826 21ur-15384 Enriched in intestine based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00165827 21ur-11441 No description available WB:WBGene00165828 21ur-7579 No description available WB:WBGene00165829 21ur-6728 No description available WB:WBGene00165830 21ur-10649 No description available WB:WBGene00165831 21ur-6825 No description available WB:WBGene00165832 21ur-7591 No description available WB:WBGene00165833 21ur-6359 No description available WB:WBGene00165834 21ur-10612 No description available WB:WBGene00165835 21ur-8004 Enriched in neurons based on RNA-seq studies. WB:WBGene00165836 21ur-13253 Is affected by cpl-1 based on RNA-seq studies. WB:WBGene00165837 21ur-10903 No description available WB:WBGene00165838 21ur-5865 No description available WB:WBGene00165839 21ur-13273 No description available WB:WBGene00165840 21ur-13967 No description available WB:WBGene00165841 21ur-13661 No description available WB:WBGene00165842 21ur-5470 No description available WB:WBGene00165843 21ur-6989 No description available WB:WBGene00165844 21ur-12290 No description available WB:WBGene00165845 21ur-10627 No description available WB:WBGene00165846 21ur-8956 No description available WB:WBGene00165847 21ur-13057 No description available WB:WBGene00165848 21ur-6647 No description available WB:WBGene00165849 21ur-13593 No description available WB:WBGene00165850 21ur-6176 No description available WB:WBGene00165851 21ur-11505 No description available WB:WBGene00165852 21ur-14669 No description available WB:WBGene00165853 21ur-10409 No description available WB:WBGene00165854 21ur-9143 No description available WB:WBGene00165855 21ur-9235 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00165856 21ur-13580 No description available WB:WBGene00165857 21ur-13633 No description available WB:WBGene00165858 21ur-6901 No description available WB:WBGene00165859 21ur-15371 No description available WB:WBGene00165860 21ur-11306 No description available WB:WBGene00165861 21ur-15209 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165862 21ur-14044 No description available WB:WBGene00165863 21ur-8232 No description available WB:WBGene00165864 21ur-6293 No description available WB:WBGene00165865 21ur-15045 No description available WB:WBGene00165866 21ur-5965 No description available WB:WBGene00165867 21ur-14883 No description available WB:WBGene00165868 21ur-13682 No description available WB:WBGene00165869 21ur-7974 No description available WB:WBGene00165870 21ur-13986 No description available WB:WBGene00165871 21ur-7158 No description available WB:WBGene00165872 21ur-6624 No description available WB:WBGene00165873 21ur-12787 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165874 21ur-14597 No description available WB:WBGene00165875 21ur-10195 No description available WB:WBGene00165876 21ur-8619 No description available WB:WBGene00165877 21ur-8579 No description available WB:WBGene00165878 21ur-7833 No description available WB:WBGene00165879 21ur-5795 No description available WB:WBGene00165880 21ur-9356 No description available WB:WBGene00165881 21ur-15068 No description available WB:WBGene00165882 21ur-12563 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165883 21ur-15210 No description available WB:WBGene00165884 21ur-11498 No description available WB:WBGene00165885 21ur-11795 No description available WB:WBGene00165886 21ur-12282 No description available WB:WBGene00165887 21ur-11045 No description available WB:WBGene00165888 21ur-14447 No description available WB:WBGene00165889 21ur-10710 No description available WB:WBGene00165890 21ur-9769 No description available WB:WBGene00165891 21ur-7722 No description available WB:WBGene00165892 21ur-11718 No description available WB:WBGene00165893 21ur-11466 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00165894 21ur-6001 No description available WB:WBGene00165895 21ur-11896 No description available WB:WBGene00165896 21ur-10329 No description available WB:WBGene00165897 21ur-9691 No description available WB:WBGene00165898 21ur-9594 No description available WB:WBGene00165899 21ur-14903 No description available WB:WBGene00165900 21ur-10219 No description available WB:WBGene00165901 21ur-12431 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00165902 21ur-12213 No description available WB:WBGene00165903 21ur-6442 No description available WB:WBGene00165904 21ur-15217 No description available WB:WBGene00165905 21ur-11877 No description available WB:WBGene00165906 21ur-14092 No description available WB:WBGene00165907 21ur-14894 No description available WB:WBGene00165908 21ur-6078 No description available WB:WBGene00165909 21ur-6636 No description available WB:WBGene00165910 21ur-9540 No description available WB:WBGene00165911 21ur-11021 No description available WB:WBGene00165912 21ur-10975 No description available WB:WBGene00165913 21ur-8170 No description available WB:WBGene00165914 21ur-12608 No description available WB:WBGene00165915 21ur-6383 No description available WB:WBGene00165916 21ur-9201 No description available WB:WBGene00165917 21ur-6217 No description available WB:WBGene00165918 21ur-12740 No description available WB:WBGene00165919 21ur-10838 No description available WB:WBGene00165920 21ur-5957 No description available WB:WBGene00165921 21ur-5502 No description available WB:WBGene00165922 21ur-5934 No description available WB:WBGene00165923 21ur-8641 No description available WB:WBGene00165924 21ur-14585 No description available WB:WBGene00165925 21ur-7880 No description available WB:WBGene00165926 21ur-7434 No description available WB:WBGene00165927 21ur-13892 No description available WB:WBGene00165928 21ur-11873 No description available WB:WBGene00165929 21ur-8580 No description available WB:WBGene00165930 21ur-14452 No description available WB:WBGene00165931 21ur-8750 No description available WB:WBGene00165932 21ur-7784 No description available WB:WBGene00165933 21ur-15136 No description available WB:WBGene00165934 21ur-12351 No description available WB:WBGene00165935 21ur-10129 No description available WB:WBGene00165936 21ur-15003 No description available WB:WBGene00165937 21ur-14828 No description available WB:WBGene00165938 21ur-11660 No description available WB:WBGene00165939 21ur-11266 No description available WB:WBGene00165940 21ur-6638 No description available WB:WBGene00165941 21ur-11204 No description available WB:WBGene00165942 21ur-8865 No description available WB:WBGene00165943 21ur-8831 No description available WB:WBGene00165944 21ur-10926 No description available WB:WBGene00165945 21ur-13375 No description available WB:WBGene00165946 21ur-8376 No description available WB:WBGene00165947 21ur-6659 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00165948 21ur-11267 No description available WB:WBGene00165949 21ur-11069 No description available WB:WBGene00165950 21ur-6098 Enriched in neurons based on RNA-seq studies. WB:WBGene00165951 21ur-14671 No description available WB:WBGene00165952 21ur-11005 No description available WB:WBGene00165953 21ur-11700 No description available WB:WBGene00165954 21ur-12675 No description available WB:WBGene00165955 21ur-11407 Is affected by skn-1 based on RNA-seq studies. WB:WBGene00165956 21ur-5598 No description available WB:WBGene00165957 21ur-12152 No description available WB:WBGene00165958 21ur-5554 No description available WB:WBGene00165959 21ur-6041 No description available WB:WBGene00165960 21ur-15648 No description available WB:WBGene00165961 21ur-14182 No description available WB:WBGene00165962 21ur-13422 No description available WB:WBGene00165963 21ur-10955 No description available WB:WBGene00165964 21ur-10048 No description available WB:WBGene00165965 21ur-14842 No description available WB:WBGene00165966 21ur-13003 No description available WB:WBGene00165967 21ur-7364 No description available WB:WBGene00165968 21ur-11754 No description available WB:WBGene00165969 21ur-7646 No description available WB:WBGene00165970 21ur-12853 No description available WB:WBGene00165971 21ur-6366 No description available WB:WBGene00165972 21ur-13942 No description available WB:WBGene00165973 21ur-12387 No description available WB:WBGene00165974 21ur-8690 No description available WB:WBGene00165975 21ur-15117 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00165976 21ur-9519 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00165977 21ur-14240 No description available WB:WBGene00165978 21ur-9095 No description available WB:WBGene00165979 21ur-11632 No description available WB:WBGene00165980 21ur-7130 No description available WB:WBGene00165981 21ur-5942 No description available WB:WBGene00165982 21ur-10113 No description available WB:WBGene00165983 21ur-8589 Is affected by hmg-3 and hlh-26 based on RNA-seq studies. WB:WBGene00165984 21ur-5819 No description available WB:WBGene00165985 21ur-11030 No description available WB:WBGene00165986 21ur-9778 No description available WB:WBGene00165987 21ur-7003 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00165988 21ur-15494 No description available WB:WBGene00165989 21ur-12621 No description available WB:WBGene00165990 21ur-7936 No description available WB:WBGene00165991 21ur-11634 No description available WB:WBGene00165992 21ur-9129 No description available WB:WBGene00165993 21ur-10402 No description available WB:WBGene00165994 21ur-13429 No description available WB:WBGene00165995 21ur-10972 No description available WB:WBGene00165996 21ur-14022 No description available WB:WBGene00165997 21ur-12785 No description available WB:WBGene00165998 21ur-9759 No description available WB:WBGene00165999 21ur-13107 No description available WB:WBGene00166000 21ur-12766 No description available WB:WBGene00166001 21ur-14414 No description available WB:WBGene00166002 21ur-10600 No description available WB:WBGene00166003 21ur-5839 No description available WB:WBGene00166004 21ur-10803 No description available WB:WBGene00166005 21ur-10489 No description available WB:WBGene00166006 21ur-9344 No description available WB:WBGene00166007 21ur-7498 No description available WB:WBGene00166008 21ur-5469 No description available WB:WBGene00166009 21ur-12742 No description available WB:WBGene00166010 21ur-11707 No description available WB:WBGene00166011 21ur-14758 Is affected by skn-1 and cpl-1 based on RNA-seq studies. WB:WBGene00166012 21ur-8153 No description available WB:WBGene00166013 21ur-12833 No description available WB:WBGene00166014 21ur-6577 Enriched in neurons based on RNA-seq studies. WB:WBGene00166015 21ur-6888 No description available WB:WBGene00166016 21ur-14657 No description available WB:WBGene00166017 21ur-9320 No description available WB:WBGene00166018 21ur-12733 No description available WB:WBGene00166019 21ur-9912 No description available WB:WBGene00166020 21ur-6017 No description available WB:WBGene00166021 21ur-10675 No description available WB:WBGene00166022 21ur-9087 No description available WB:WBGene00166023 21ur-5708 No description available WB:WBGene00166024 21ur-7849 No description available WB:WBGene00166025 21ur-9306 No description available WB:WBGene00166026 21ur-8769 No description available WB:WBGene00166027 21ur-13995 No description available WB:WBGene00166028 21ur-12998 Is affected by rsr-2 based on tiling array studies. WB:WBGene00166029 21ur-9860 Enriched in AFD based on RNA-seq studies. WB:WBGene00166030 21ur-9693 No description available WB:WBGene00166031 21ur-12363 No description available WB:WBGene00166032 21ur-8487 No description available WB:WBGene00166033 21ur-7822 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00166034 21ur-7461 Enriched in neurons based on RNA-seq studies. WB:WBGene00166035 21ur-9763 No description available WB:WBGene00166036 21ur-13502 No description available WB:WBGene00166037 21ur-15244 Enriched in neurons based on RNA-seq studies. Is affected by unc-70; acr-2; and set-2 based on RNA-seq studies. WB:WBGene00166038 21ur-14416 No description available WB:WBGene00166039 21ur-11216 No description available WB:WBGene00166040 21ur-10778 No description available WB:WBGene00166041 21ur-10581 No description available WB:WBGene00166042 21ur-8498 No description available WB:WBGene00166043 21ur-13888 No description available WB:WBGene00166044 21ur-7621 No description available WB:WBGene00166045 21ur-5670 No description available WB:WBGene00166046 21ur-12071 No description available WB:WBGene00166047 21ur-5970 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00166048 21ur-15444 No description available WB:WBGene00166049 21ur-5656 No description available WB:WBGene00166050 21ur-7524 No description available WB:WBGene00166051 21ur-6086 No description available WB:WBGene00166052 21ur-12085 No description available WB:WBGene00166053 21ur-5979 No description available WB:WBGene00166054 21ur-8136 No description available WB:WBGene00166055 21ur-10520 No description available WB:WBGene00166057 21ur-12941 No description available WB:WBGene00166058 21ur-9514 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00166059 21ur-13638 No description available WB:WBGene00166060 21ur-7104 No description available WB:WBGene00166062 21ur-9524 No description available WB:WBGene00166063 21ur-9570 No description available WB:WBGene00166064 21ur-9948 No description available WB:WBGene00166065 21ur-6613 No description available WB:WBGene00166066 21ur-8512 No description available WB:WBGene00166067 21ur-10515 No description available WB:WBGene00166068 21ur-6256 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00166069 21ur-6833 No description available WB:WBGene00166070 21ur-15467 No description available WB:WBGene00166071 21ur-14498 No description available WB:WBGene00166072 21ur-10340 No description available WB:WBGene00166073 21ur-12821 No description available WB:WBGene00166074 21ur-8452 No description available WB:WBGene00166075 21ur-7076 No description available WB:WBGene00166076 21ur-9122 No description available WB:WBGene00166077 21ur-7035 No description available WB:WBGene00166078 21ur-12924 No description available WB:WBGene00166079 21ur-10181 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00166080 21ur-8949 No description available WB:WBGene00166081 21ur-7526 No description available WB:WBGene00166082 21ur-10458 Is affected by ints-5 based on RNA-seq studies. WB:WBGene00166083 21ur-14019 No description available WB:WBGene00166084 21ur-8596 No description available WB:WBGene00166085 21ur-13907 No description available WB:WBGene00166086 21ur-15096 No description available WB:WBGene00166087 21ur-14650 No description available WB:WBGene00166088 21ur-7466 No description available WB:WBGene00166089 21ur-6168 No description available WB:WBGene00166090 21ur-12692 No description available WB:WBGene00166091 21ur-10018 No description available WB:WBGene00166092 21ur-8016 No description available WB:WBGene00166093 21ur-6969 No description available WB:WBGene00166094 21ur-5614 No description available WB:WBGene00166095 21ur-15318 No description available WB:WBGene00166096 21ur-13540 No description available WB:WBGene00166097 21ur-6964 No description available WB:WBGene00166098 21ur-14556 No description available WB:WBGene00166099 21ur-9607 No description available WB:WBGene00166100 21ur-6496 No description available WB:WBGene00166101 21ur-14162 No description available WB:WBGene00166102 21ur-11962 No description available WB:WBGene00166103 21ur-11710 No description available WB:WBGene00166104 21ur-9239 No description available WB:WBGene00166105 21ur-15674 No description available WB:WBGene00166106 21ur-5758 No description available WB:WBGene00166107 21ur-7763 No description available WB:WBGene00166108 21ur-11808 No description available WB:WBGene00166109 21ur-8534 No description available WB:WBGene00166110 21ur-6312 No description available WB:WBGene00166111 21ur-13025 No description available WB:WBGene00166112 21ur-12289 No description available WB:WBGene00166113 21ur-11599 No description available WB:WBGene00166114 21ur-14500 No description available WB:WBGene00166115 21ur-12303 No description available WB:WBGene00166116 21ur-15694 No description available WB:WBGene00166117 21ur-12251 No description available WB:WBGene00166118 21ur-10244 No description available WB:WBGene00166119 21ur-6895 No description available WB:WBGene00166120 21ur-10967 No description available WB:WBGene00166121 21ur-11166 No description available WB:WBGene00166122 21ur-10130 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00166123 21ur-7211 No description available WB:WBGene00166124 21ur-15655 No description available WB:WBGene00166125 21ur-6593 Enriched in neurons based on RNA-seq studies. WB:WBGene00166126 21ur-7057 No description available WB:WBGene00166127 21ur-14129 Enriched in neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00166128 21ur-11969 Enriched in neurons based on RNA-seq studies. WB:WBGene00166129 21ur-9381 No description available WB:WBGene00166130 21ur-8523 Enriched in neurons based on RNA-seq studies. WB:WBGene00166131 21ur-8446 No description available WB:WBGene00166132 21ur-7890 No description available WB:WBGene00166133 21ur-11920 No description available WB:WBGene00166134 21ur-12657 No description available WB:WBGene00166135 21ur-9020 No description available WB:WBGene00166136 21ur-7448 No description available WB:WBGene00166137 21ur-13723 No description available WB:WBGene00166138 21ur-15053 No description available WB:WBGene00166139 21ur-12142 No description available WB:WBGene00166140 21ur-12574 No description available WB:WBGene00166141 21ur-13817 No description available WB:WBGene00166142 21ur-11669 No description available WB:WBGene00166143 21ur-6827 No description available WB:WBGene00166144 21ur-10591 No description available WB:WBGene00166145 21ur-15192 No description available WB:WBGene00166146 21ur-11434 No description available WB:WBGene00166147 21ur-10239 No description available WB:WBGene00166148 21ur-12373 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00166149 21ur-5668 No description available WB:WBGene00166150 21ur-7191 No description available WB:WBGene00166151 21ur-14878 No description available WB:WBGene00166152 21ur-12445 No description available WB:WBGene00166153 21ur-7764 No description available WB:WBGene00166154 21ur-9834 No description available WB:WBGene00166155 21ur-9803 No description available WB:WBGene00166156 21ur-5535 No description available WB:WBGene00166157 21ur-11391 No description available WB:WBGene00166158 21ur-15070 No description available WB:WBGene00166159 21ur-6600 No description available WB:WBGene00166160 21ur-14161 No description available WB:WBGene00166161 21ur-10145 No description available WB:WBGene00166162 21ur-5464 No description available WB:WBGene00166163 21ur-14122 No description available WB:WBGene00166164 21ur-9021 No description available WB:WBGene00166165 21ur-5635 No description available WB:WBGene00166166 21ur-7236 No description available WB:WBGene00166167 21ur-6161 No description available WB:WBGene00166168 21ur-6746 No description available WB:WBGene00166169 21ur-14344 No description available WB:WBGene00166170 21ur-10798 No description available WB:WBGene00166171 21ur-14787 Enriched in neurons based on RNA-seq studies. WB:WBGene00166172 21ur-12603 Enriched in neurons based on RNA-seq studies. WB:WBGene00166173 21ur-5927 No description available WB:WBGene00166174 21ur-13741 Enriched in neurons based on RNA-seq studies. WB:WBGene00166175 21ur-9388 No description available WB:WBGene00166176 21ur-9216 No description available WB:WBGene00166177 21ur-6804 No description available WB:WBGene00166178 21ur-10430 No description available WB:WBGene00166179 21ur-14513 No description available WB:WBGene00166180 21ur-8186 No description available WB:WBGene00166181 21ur-12775 No description available WB:WBGene00166182 21ur-5694 No description available WB:WBGene00166183 21ur-14764 No description available WB:WBGene00166184 21ur-12389 No description available WB:WBGene00166185 21ur-6527 No description available WB:WBGene00166186 21ur-12946 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00166187 21ur-11771 No description available WB:WBGene00166188 21ur-15223 Enriched in neurons based on RNA-seq studies. WB:WBGene00166189 21ur-13417 No description available WB:WBGene00166190 21ur-12797 No description available WB:WBGene00166191 21ur-14072 No description available WB:WBGene00166192 21ur-13534 No description available WB:WBGene00166193 21ur-13754 No description available WB:WBGene00166194 21ur-14939 No description available WB:WBGene00166195 21ur-12276 No description available WB:WBGene00166196 21ur-10206 No description available WB:WBGene00166197 21ur-13571 No description available WB:WBGene00166198 21ur-14276 No description available WB:WBGene00166199 21ur-13249 No description available WB:WBGene00166200 21ur-9665 No description available WB:WBGene00166201 21ur-5714 No description available WB:WBGene00166202 21ur-13239 No description available WB:WBGene00166203 21ur-14148 No description available WB:WBGene00166204 21ur-13606 No description available WB:WBGene00166205 21ur-8777 No description available WB:WBGene00166206 21ur-15010 No description available WB:WBGene00166207 21ur-9729 No description available WB:WBGene00166208 21ur-7815 No description available WB:WBGene00166209 21ur-7884 No description available WB:WBGene00166210 21ur-6349 Enriched in neurons based on RNA-seq studies. WB:WBGene00166211 21ur-10510 No description available WB:WBGene00166212 21ur-7370 No description available WB:WBGene00166213 21ur-12300 No description available WB:WBGene00166214 21ur-5742 No description available WB:WBGene00166215 21ur-10548 No description available WB:WBGene00166216 21ur-8703 No description available WB:WBGene00166217 21ur-12201 No description available WB:WBGene00166218 21ur-15470 No description available WB:WBGene00166219 21ur-12193 No description available WB:WBGene00166220 21ur-13144 No description available WB:WBGene00166221 21ur-15328 No description available WB:WBGene00166222 21ur-14808 No description available WB:WBGene00166223 21ur-13696 No description available WB:WBGene00166224 21ur-13244 No description available WB:WBGene00166225 21ur-10398 Is affected by daf-2 based on microarray studies. WB:WBGene00166226 21ur-7737 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00166227 21ur-7029 Enriched in neurons based on RNA-seq studies. WB:WBGene00166228 21ur-9444 No description available WB:WBGene00166229 21ur-6874 No description available WB:WBGene00166230 21ur-11613 No description available WB:WBGene00166231 21ur-14698 No description available WB:WBGene00166232 21ur-11235 No description available WB:WBGene00166233 21ur-10736 No description available WB:WBGene00166234 21ur-12307 No description available WB:WBGene00166235 21ur-10387 Is affected by paraquat based on RNA-seq studies. WB:WBGene00166236 21ur-8267 No description available WB:WBGene00166237 21ur-6265 No description available WB:WBGene00166238 21ur-15666 No description available WB:WBGene00166239 21ur-13113 No description available WB:WBGene00166240 21ur-15077 No description available WB:WBGene00166241 21ur-8573 No description available WB:WBGene00166242 21ur-7904 No description available WB:WBGene00166243 21ur-12556 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00166244 21ur-9587 No description available WB:WBGene00166245 21ur-8649 No description available WB:WBGene00166246 21ur-6513 No description available WB:WBGene00166247 21ur-11779 No description available WB:WBGene00166248 21ur-9206 No description available WB:WBGene00166249 21ur-7897 No description available WB:WBGene00166250 21ur-10853 No description available WB:WBGene00166251 21ur-7139 No description available WB:WBGene00166252 21ur-11352 No description available WB:WBGene00166253 21ur-14426 No description available WB:WBGene00166254 21ur-14544 No description available WB:WBGene00166255 21ur-14617 No description available WB:WBGene00166256 21ur-5822 No description available WB:WBGene00166257 21ur-14774 No description available WB:WBGene00166258 21ur-6704 No description available WB:WBGene00166259 21ur-14064 No description available WB:WBGene00166260 21ur-12354 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00166261 21ur-8127 No description available WB:WBGene00166262 21ur-6551 No description available WB:WBGene00166263 21ur-10490 No description available WB:WBGene00166264 21ur-12067 No description available WB:WBGene00166265 21ur-13847 No description available WB:WBGene00166266 21ur-7554 No description available WB:WBGene00166267 21ur-7970 No description available WB:WBGene00166268 21ur-12322 No description available WB:WBGene00166269 21ur-14438 No description available WB:WBGene00166270 21ur-14994 No description available WB:WBGene00166271 21ur-11057 No description available WB:WBGene00166272 21ur-7378 No description available WB:WBGene00166273 21ur-8507 No description available WB:WBGene00166274 21ur-11916 Is affected by several genes including lem-2; emr-1; and etr-1 based on RNA-seq studies. WB:WBGene00166275 21ur-9819 No description available WB:WBGene00166276 21ur-14030 No description available WB:WBGene00166277 21ur-13539 No description available WB:WBGene00166278 21ur-6864 No description available WB:WBGene00166279 21ur-8275 No description available WB:WBGene00166280 21ur-5805 No description available WB:WBGene00166281 21ur-8503 No description available WB:WBGene00166282 21ur-11680 No description available WB:WBGene00166283 21ur-6520 No description available WB:WBGene00166284 21ur-14392 No description available WB:WBGene00166285 21ur-11942 No description available WB:WBGene00166286 21ur-5642 No description available WB:WBGene00166287 21ur-7016 No description available WB:WBGene00166288 21ur-15508 No description available WB:WBGene00166289 21ur-13014 No description available WB:WBGene00166290 21ur-14744 No description available WB:WBGene00166291 21ur-11642 No description available WB:WBGene00166292 21ur-7725 Enriched in neurons based on RNA-seq studies. WB:WBGene00166293 21ur-11322 No description available WB:WBGene00166294 21ur-10480 No description available WB:WBGene00166295 21ur-6327 No description available WB:WBGene00166296 21ur-9942 No description available WB:WBGene00166297 21ur-12721 Enriched in neurons based on RNA-seq studies. WB:WBGene00166298 21ur-6132 No description available WB:WBGene00166299 21ur-10230 No description available WB:WBGene00166300 21ur-13314 No description available WB:WBGene00166301 21ur-11521 No description available WB:WBGene00166302 21ur-8650 Is affected by wdr-5.1 based on RNA-seq studies. WB:WBGene00166303 21ur-13233 No description available WB:WBGene00166304 21ur-11583 No description available WB:WBGene00166305 21ur-8835 No description available WB:WBGene00166306 21ur-8138 No description available WB:WBGene00166307 21ur-10671 No description available WB:WBGene00166308 21ur-9091 No description available WB:WBGene00166309 21ur-5472 No description available WB:WBGene00166310 21ur-11739 No description available WB:WBGene00166311 21ur-12330 No description available WB:WBGene00166312 21ur-12019 No description available WB:WBGene00166313 21ur-14196 No description available WB:WBGene00166314 21ur-13317 No description available WB:WBGene00166315 21ur-11678 No description available WB:WBGene00166316 21ur-9085 No description available WB:WBGene00166317 21ur-6910 No description available WB:WBGene00166318 21ur-12209 No description available WB:WBGene00166319 21ur-10191 No description available WB:WBGene00166320 21ur-6840 No description available WB:WBGene00166321 21ur-6861 No description available WB:WBGene00166322 21ur-13840 Enriched in neurons based on RNA-seq studies. WB:WBGene00166323 21ur-6917 No description available WB:WBGene00166324 21ur-8621 No description available WB:WBGene00166325 21ur-15413 No description available WB:WBGene00166326 21ur-13322 No description available WB:WBGene00166327 21ur-9190 No description available WB:WBGene00166328 21ur-7979 No description available WB:WBGene00166329 21ur-11402 No description available WB:WBGene00166330 21ur-8249 Enriched in AFD based on RNA-seq studies. WB:WBGene00166331 21ur-9108 No description available WB:WBGene00166332 21ur-13866 No description available WB:WBGene00166333 21ur-6234 No description available WB:WBGene00166334 21ur-14186 No description available WB:WBGene00166335 21ur-10229 No description available WB:WBGene00166336 21ur-10088 No description available WB:WBGene00166337 21ur-8627 No description available WB:WBGene00166338 21ur-13211 No description available WB:WBGene00166339 21ur-5498 No description available WB:WBGene00166340 21ur-14779 Is affected by lem-2; emr-1; and cpl-1 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies. WB:WBGene00166341 21ur-12761 No description available WB:WBGene00166342 21ur-9297 No description available WB:WBGene00166343 21ur-10261 No description available WB:WBGene00166344 21ur-8659 No description available WB:WBGene00166345 21ur-12771 No description available WB:WBGene00166346 21ur-15000 No description available WB:WBGene00166347 21ur-13088 No description available WB:WBGene00166348 21ur-15520 No description available WB:WBGene00166349 21ur-12874 No description available WB:WBGene00166350 21ur-6908 Enriched in neurons based on RNA-seq studies. WB:WBGene00166351 21ur-8286 No description available WB:WBGene00166352 21ur-14272 No description available WB:WBGene00166353 21ur-14020 No description available WB:WBGene00166354 21ur-5812 No description available WB:WBGene00166355 21ur-8997 No description available WB:WBGene00166356 21ur-13671 No description available WB:WBGene00166357 21ur-8482 No description available WB:WBGene00166358 21ur-9865 No description available WB:WBGene00166359 21ur-8463 No description available WB:WBGene00166360 21ur-12575 No description available WB:WBGene00166361 21ur-9951 No description available WB:WBGene00166362 21ur-15434 No description available WB:WBGene00166363 21ur-9595 No description available WB:WBGene00166364 21ur-5816 Enriched in neurons based on RNA-seq studies. WB:WBGene00166365 21ur-6034 No description available WB:WBGene00166366 21ur-5827 No description available WB:WBGene00166367 21ur-14114 No description available WB:WBGene00166368 21ur-10098 No description available WB:WBGene00166369 21ur-6558 No description available WB:WBGene00166370 21ur-9573 No description available WB:WBGene00166371 21ur-14202 No description available WB:WBGene00166372 21ur-14887 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00166373 21ur-11952 No description available WB:WBGene00166374 21ur-13227 No description available WB:WBGene00166375 21ur-15579 No description available WB:WBGene00166376 21ur-7216 No description available WB:WBGene00166377 21ur-10793 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00166378 21ur-12318 No description available WB:WBGene00166379 21ur-6426 No description available WB:WBGene00166380 21ur-13326 No description available WB:WBGene00166381 21ur-14176 No description available WB:WBGene00166382 21ur-12419 No description available WB:WBGene00166383 21ur-11588 No description available WB:WBGene00166384 21ur-5769 No description available WB:WBGene00166385 21ur-10722 No description available WB:WBGene00166386 21ur-13397 No description available WB:WBGene00166387 21ur-9203 No description available WB:WBGene00166388 21ur-7753 No description available WB:WBGene00166389 21ur-14918 Enriched in neurons based on RNA-seq studies. WB:WBGene00166390 21ur-13053 No description available WB:WBGene00166391 21ur-9191 No description available WB:WBGene00166392 21ur-6762 No description available WB:WBGene00166393 21ur-11766 No description available WB:WBGene00166394 21ur-11490 No description available WB:WBGene00166395 21ur-14603 No description available WB:WBGene00166396 21ur-15597 No description available WB:WBGene00166397 21ur-14312 No description available WB:WBGene00166398 21ur-9187 No description available WB:WBGene00166399 21ur-11473 No description available WB:WBGene00166400 21ur-7168 No description available WB:WBGene00166401 21ur-8809 No description available WB:WBGene00166402 21ur-13918 No description available WB:WBGene00166403 21ur-7476 No description available WB:WBGene00166404 21ur-6845 No description available WB:WBGene00166405 21ur-15484 No description available WB:WBGene00166406 21ur-13443 No description available WB:WBGene00166407 21ur-8087 No description available WB:WBGene00166408 21ur-8060 No description available WB:WBGene00166409 21ur-13875 No description available WB:WBGene00166410 21ur-11153 No description available WB:WBGene00166411 21ur-7487 No description available WB:WBGene00166412 21ur-14959 Is affected by eat-2 based on microarray studies. WB:WBGene00166413 21ur-12186 No description available WB:WBGene00166414 21ur-12664 No description available WB:WBGene00166415 21ur-15236 No description available WB:WBGene00166416 21ur-12138 No description available WB:WBGene00166417 21ur-14264 No description available WB:WBGene00166418 21ur-15146 No description available WB:WBGene00166419 21ur-14303 No description available WB:WBGene00166420 21ur-10347 No description available WB:WBGene00166421 21ur-9531 No description available WB:WBGene00166422 21ur-5481 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00166423 21ur-9276 No description available WB:WBGene00166424 21ur-14700 No description available WB:WBGene00166425 21ur-11941 Enriched in neurons based on RNA-seq studies. WB:WBGene00166426 21ur-9422 No description available WB:WBGene00166427 21ur-8120 No description available WB:WBGene00166428 21ur-8227 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00166429 21ur-9254 No description available WB:WBGene00166430 21ur-8748 No description available WB:WBGene00166431 21ur-9505 No description available WB:WBGene00166432 21ur-13164 No description available WB:WBGene00166433 21ur-13668 No description available WB:WBGene00166434 21ur-12043 No description available WB:WBGene00166435 21ur-8405 No description available WB:WBGene00166436 21ur-10877 No description available WB:WBGene00166437 21ur-12441 Enriched in neurons based on RNA-seq studies. WB:WBGene00166438 21ur-8719 No description available WB:WBGene00166439 21ur-12134 No description available WB:WBGene00166440 21ur-6207 No description available WB:WBGene00166441 21ur-15237 No description available WB:WBGene00166442 21ur-9735 No description available WB:WBGene00166443 21ur-8924 No description available WB:WBGene00166444 21ur-13767 Is affected by rnp-6; blmp-1; and cpl-1 based on RNA-seq studies. WB:WBGene00166445 21ur-10770 No description available WB:WBGene00166446 21ur-9013 No description available WB:WBGene00166447 21ur-10455 No description available WB:WBGene00166448 21ur-13405 No description available WB:WBGene00166449 21ur-5844 Enriched in neurons based on RNA-seq studies. WB:WBGene00166450 21ur-14718 No description available WB:WBGene00166451 21ur-11862 No description available WB:WBGene00166452 21ur-5953 No description available WB:WBGene00166453 21ur-6780 No description available WB:WBGene00166454 21ur-15404 No description available WB:WBGene00166455 21ur-6786 No description available WB:WBGene00166456 21ur-13042 No description available WB:WBGene00166457 21ur-10352 No description available WB:WBGene00166458 21ur-13497 No description available WB:WBGene00166459 21ur-13756 No description available WB:WBGene00166460 21ur-9838 No description available WB:WBGene00166461 21ur-14834 No description available WB:WBGene00166462 21ur-10160 No description available WB:WBGene00166463 21ur-11508 No description available WB:WBGene00166464 21ur-13728 No description available WB:WBGene00166465 21ur-8675 No description available WB:WBGene00166466 21ur-7665 No description available WB:WBGene00166467 21ur-10556 Is affected by lem-2; emr-1; and etr-1 based on RNA-seq studies. WB:WBGene00166468 21ur-13311 No description available WB:WBGene00166469 21ur-8884 No description available WB:WBGene00166470 21ur-8282 No description available WB:WBGene00166471 21ur-9403 No description available WB:WBGene00166472 21ur-9303 No description available WB:WBGene00166473 21ur-12898 No description available WB:WBGene00166474 21ur-13911 No description available WB:WBGene00166475 21ur-10997 No description available WB:WBGene00166476 21ur-6588 No description available WB:WBGene00166477 21ur-7206 No description available WB:WBGene00166478 21ur-8017 No description available WB:WBGene00166479 21ur-9846 No description available WB:WBGene00166480 21ur-8990 Enriched in neurons based on RNA-seq studies. WB:WBGene00166481 21ur-14450 No description available WB:WBGene00166482 21ur-7916 No description available WB:WBGene00166483 21ur-12287 No description available WB:WBGene00166484 21ur-7543 No description available WB:WBGene00166485 21ur-11925 No description available WB:WBGene00166486 21ur-8746 No description available WB:WBGene00166487 21ur-14471 No description available WB:WBGene00166488 21ur-9039 No description available WB:WBGene00166489 21ur-9644 No description available WB:WBGene00166490 21ur-13578 No description available WB:WBGene00166491 21ur-8448 No description available WB:WBGene00166492 21ur-6772 No description available WB:WBGene00166493 21ur-10442 No description available WB:WBGene00166494 21ur-13731 No description available WB:WBGene00166495 21ur-8987 No description available WB:WBGene00166496 21ur-14701 No description available WB:WBGene00166497 21ur-9958 No description available WB:WBGene00166498 21ur-5832 No description available WB:WBGene00166499 21ur-6672 No description available WB:WBGene00166500 21ur-12280 No description available WB:WBGene00166501 21ur-10435 No description available WB:WBGene00166502 21ur-9844 Enriched in neurons based on RNA-seq studies. WB:WBGene00166503 21ur-9554 No description available WB:WBGene00166504 21ur-5996 No description available WB:WBGene00166505 21ur-12296 No description available WB:WBGene00166506 21ur-14005 No description available WB:WBGene00166507 21ur-5560 No description available WB:WBGene00166508 21ur-8564 No description available WB:WBGene00166509 21ur-10447 No description available WB:WBGene00166510 21ur-11528 No description available WB:WBGene00166511 21ur-9221 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00166512 21ur-13484 No description available WB:WBGene00166513 21ur-9018 Enriched in neurons based on RNA-seq studies. WB:WBGene00166514 21ur-8220 No description available WB:WBGene00166515 21ur-14404 No description available WB:WBGene00166516 21ur-13218 No description available WB:WBGene00166517 21ur-6227 No description available WB:WBGene00166518 21ur-13364 No description available WB:WBGene00166519 21ur-13015 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00166520 21ur-14531 No description available WB:WBGene00166521 21ur-6338 Enriched in neurons based on RNA-seq studies. WB:WBGene00166522 21ur-12838 No description available WB:WBGene00166523 21ur-14738 Enriched in neurons based on RNA-seq studies. WB:WBGene00166524 21ur-11838 No description available WB:WBGene00166525 21ur-14979 No description available WB:WBGene00166526 21ur-7301 Enriched in neurons based on RNA-seq studies. WB:WBGene00166527 21ur-6983 Is affected by eat-2 based on microarray studies. WB:WBGene00166528 21ur-7807 No description available WB:WBGene00166529 21ur-14009 No description available WB:WBGene00166530 21ur-12943 No description available WB:WBGene00166531 21ur-13333 No description available WB:WBGene00166532 21ur-8297 No description available WB:WBGene00166533 21ur-11319 No description available WB:WBGene00166534 21ur-15497 No description available WB:WBGene00166535 21ur-13561 No description available WB:WBGene00166536 21ur-8492 No description available WB:WBGene00166537 21ur-8669 No description available WB:WBGene00166538 21ur-9984 No description available WB:WBGene00166539 21ur-14792 No description available WB:WBGene00166540 21ur-14509 No description available WB:WBGene00166541 21ur-9054 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00166542 21ur-8520 No description available WB:WBGene00166543 21ur-6154 No description available WB:WBGene00166544 21ur-11608 No description available WB:WBGene00166545 21ur-8907 No description available WB:WBGene00166546 21ur-8795 No description available WB:WBGene00166547 21ur-11842 No description available WB:WBGene00166548 21ur-5949 No description available WB:WBGene00166549 21ur-14150 No description available WB:WBGene00166550 21ur-11388 No description available WB:WBGene00166551 21ur-11198 No description available WB:WBGene00166552 21ur-12466 No description available WB:WBGene00166553 21ur-10811 No description available WB:WBGene00166554 21ur-9390 No description available WB:WBGene00166555 21ur-6742 No description available WB:WBGene00166556 21ur-13101 No description available WB:WBGene00166557 21ur-12397 No description available WB:WBGene00166558 21ur-8475 No description available WB:WBGene00166559 21ur-13686 No description available WB:WBGene00166560 21ur-7315 No description available WB:WBGene00166561 21ur-14983 No description available WB:WBGene00166562 21ur-14381 No description available WB:WBGene00166563 21ur-9979 No description available WB:WBGene00166564 21ur-10979 No description available WB:WBGene00166565 21ur-7863 No description available WB:WBGene00166566 21ur-15347 No description available WB:WBGene00166567 21ur-13845 Enriched in neurons based on RNA-seq studies. Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00166568 21ur-6460 No description available WB:WBGene00166569 21ur-12246 No description available WB:WBGene00166570 21ur-8519 No description available WB:WBGene00166571 21ur-12553 No description available WB:WBGene00166572 21ur-7811 No description available WB:WBGene00166573 21ur-5856 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00166574 21ur-12814 No description available WB:WBGene00166575 21ur-11964 No description available WB:WBGene00166576 21ur-6245 No description available WB:WBGene00166577 21ur-15079 No description available WB:WBGene00166578 21ur-8470 No description available WB:WBGene00166579 21ur-15692 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00166580 21ur-11573 No description available WB:WBGene00166581 21ur-11272 No description available WB:WBGene00166582 21ur-9586 No description available WB:WBGene00166583 21ur-8541 No description available WB:WBGene00166584 21ur-10254 No description available WB:WBGene00166585 21ur-7692 No description available WB:WBGene00166586 21ur-5682 No description available WB:WBGene00166587 21ur-8428 No description available WB:WBGene00166588 21ur-5722 No description available WB:WBGene00166589 21ur-7293 Enriched in neurons based on RNA-seq studies. WB:WBGene00166590 21ur-15351 No description available WB:WBGene00166591 21ur-12339 No description available WB:WBGene00166592 21ur-15683 No description available WB:WBGene00166593 21ur-7896 No description available WB:WBGene00166594 21ur-12866 No description available WB:WBGene00166595 21ur-8912 No description available WB:WBGene00166596 21ur-6539 Enriched in neurons based on RNA-seq studies. WB:WBGene00166597 21ur-13096 No description available WB:WBGene00166598 21ur-14241 No description available WB:WBGene00166599 21ur-7150 No description available WB:WBGene00166600 21ur-11560 No description available WB:WBGene00166601 21ur-14248 No description available WB:WBGene00166602 21ur-9974 No description available WB:WBGene00166603 21ur-9319 No description available WB:WBGene00166604 21ur-14445 No description available WB:WBGene00166605 21ur-8741 No description available WB:WBGene00166606 21ur-14577 No description available WB:WBGene00166607 21ur-13390 No description available WB:WBGene00166608 21ur-8383 No description available WB:WBGene00166609 21ur-6193 No description available WB:WBGene00166610 21ur-9812 No description available WB:WBGene00166611 21ur-11732 No description available WB:WBGene00166612 21ur-12867 No description available WB:WBGene00166613 21ur-15072 Is affected by daf-2 based on microarray studies. WB:WBGene00166614 21ur-9660 No description available WB:WBGene00166615 21ur-7258 No description available WB:WBGene00166616 21ur-6959 No description available WB:WBGene00166617 21ur-9175 No description available WB:WBGene00166618 21ur-9851 No description available WB:WBGene00166619 21ur-10355 No description available WB:WBGene00166620 21ur-6069 No description available WB:WBGene00166621 21ur-7266 No description available WB:WBGene00166622 21ur-15603 No description available WB:WBGene00166623 21ur-11073 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00166624 21ur-10306 No description available WB:WBGene00166625 21ur-12048 No description available WB:WBGene00166626 21ur-14565 No description available WB:WBGene00166627 21ur-9658 No description available WB:WBGene00166628 21ur-9098 No description available WB:WBGene00166629 21ur-13074 No description available WB:WBGene00166630 21ur-12520 No description available WB:WBGene00166631 21ur-13698 No description available WB:WBGene00166632 21ur-8411 No description available WB:WBGene00166633 21ur-15187 No description available WB:WBGene00166634 21ur-12801 No description available WB:WBGene00166635 21ur-8844 No description available WB:WBGene00166636 21ur-7935 No description available WB:WBGene00166637 21ur-7744 No description available WB:WBGene00166638 21ur-8919 No description available WB:WBGene00166639 21ur-12885 No description available WB:WBGene00166640 21ur-11132 No description available WB:WBGene00166641 21ur-7959 No description available WB:WBGene00166642 21ur-12688 No description available WB:WBGene00166643 21ur-8692 No description available WB:WBGene00166644 21ur-9569 No description available WB:WBGene00166645 21ur-7608 No description available WB:WBGene00166646 21ur-8141 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00166647 21ur-5615 No description available WB:WBGene00166648 21ur-12425 No description available WB:WBGene00166649 21ur-9805 No description available WB:WBGene00166650 21ur-6871 No description available WB:WBGene00166651 21ur-15394 No description available WB:WBGene00166652 21ur-10122 No description available WB:WBGene00166653 21ur-15337 No description available WB:WBGene00166654 21ur-13951 No description available WB:WBGene00166655 21ur-14468 No description available WB:WBGene00166656 21ur-10222 No description available WB:WBGene00166657 21ur-8082 No description available WB:WBGene00166658 21ur-8548 No description available WB:WBGene00166659 21ur-11662 No description available WB:WBGene00166660 21ur-6945 No description available WB:WBGene00166661 21ur-14159 Enriched in neurons based on RNA-seq studies. WB:WBGene00166662 21ur-7242 No description available WB:WBGene00166663 21ur-7044 No description available WB:WBGene00166664 21ur-14949 No description available WB:WBGene00166665 21ur-6920 No description available WB:WBGene00166666 21ur-13410 No description available WB:WBGene00166667 21ur-11035 No description available WB:WBGene00166668 21ur-13611 No description available WB:WBGene00166669 21ur-8902 No description available WB:WBGene00166670 21ur-14388 No description available WB:WBGene00166671 21ur-10888 No description available WB:WBGene00166672 21ur-13761 No description available WB:WBGene00166673 21ur-5650 No description available WB:WBGene00166674 21ur-14082 No description available WB:WBGene00166675 21ur-14012 No description available WB:WBGene00166676 21ur-10141 No description available WB:WBGene00166677 21ur-15623 No description available WB:WBGene00166678 21ur-10159 No description available WB:WBGene00166679 21ur-13191 No description available WB:WBGene00166680 21ur-11827 No description available WB:WBGene00166681 21ur-8637 No description available WB:WBGene00166682 21ur-13553 No description available WB:WBGene00166683 21ur-10170 No description available WB:WBGene00166684 21ur-11139 No description available WB:WBGene00166685 21ur-10173 No description available WB:WBGene00166686 21ur-15247 Enriched in neurons based on RNA-seq studies. WB:WBGene00166687 21ur-13493 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00166688 21ur-8040 No description available WB:WBGene00166689 21ur-10754 No description available WB:WBGene00166690 21ur-11501 No description available WB:WBGene00166691 21ur-11379 No description available WB:WBGene00166692 21ur-12400 No description available WB:WBGene00166693 21ur-8977 No description available WB:WBGene00166694 21ur-8212 No description available WB:WBGene00166695 21ur-15618 No description available WB:WBGene00166696 21ur-15088 No description available WB:WBGene00166697 21ur-10004 No description available WB:WBGene00166698 21ur-6581 No description available WB:WBGene00166699 21ur-15150 Enriched in neurons based on RNA-seq studies. WB:WBGene00166700 21ur-12706 No description available WB:WBGene00166701 21ur-12589 No description available WB:WBGene00166702 21ur-12075 No description available WB:WBGene00166703 21ur-11117 No description available WB:WBGene00166704 21ur-11687 No description available WB:WBGene00166705 21ur-8030 No description available WB:WBGene00166706 21ur-14568 No description available WB:WBGene00166707 21ur-11008 No description available WB:WBGene00166708 21ur-6800 No description available WB:WBGene00166709 21ur-5861 No description available WB:WBGene00166710 21ur-6493 No description available WB:WBGene00166711 21ur-8250 No description available WB:WBGene00166712 21ur-10762 No description available WB:WBGene00166713 21ur-11417 No description available WB:WBGene00166714 21ur-8643 No description available WB:WBGene00166715 21ur-12962 No description available WB:WBGene00166716 21ur-6118 Enriched in neurons based on RNA-seq studies. WB:WBGene00166717 21ur-14037 No description available WB:WBGene00166718 21ur-10470 No description available WB:WBGene00166719 21ur-12935 No description available WB:WBGene00166720 21ur-9185 No description available WB:WBGene00166721 21ur-6272 No description available WB:WBGene00166722 21ur-15025 No description available WB:WBGene00166723 21ur-7114 No description available WB:WBGene00166724 21ur-12115 No description available WB:WBGene00166725 21ur-15345 No description available WB:WBGene00166726 21ur-13079 No description available WB:WBGene00166727 21ur-12670 No description available WB:WBGene00166728 21ur-9369 No description available WB:WBGene00166729 21ur-8615 No description available WB:WBGene00166730 21ur-9915 No description available WB:WBGene00166731 21ur-11752 No description available WB:WBGene00166732 21ur-10291 No description available WB:WBGene00166733 21ur-11801 No description available WB:WBGene00166734 21ur-13783 No description available WB:WBGene00166735 21ur-10861 Enriched in neurons based on RNA-seq studies. WB:WBGene00166736 21ur-7252 No description available WB:WBGene00166737 21ur-7906 No description available WB:WBGene00166738 21ur-7658 Enriched in neurons based on RNA-seq studies. WB:WBGene00166739 21ur-7457 Is affected by set-2 based on RNA-seq studies. WB:WBGene00166740 21ur-6369 Enriched in neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00166741 21ur-7450 No description available WB:WBGene00166742 21ur-8106 No description available WB:WBGene00166743 21ur-13958 No description available WB:WBGene00166744 21ur-10881 No description available WB:WBGene00166745 21ur-12315 No description available WB:WBGene00166746 21ur-9361 No description available WB:WBGene00166747 21ur-13302 No description available WB:WBGene00166748 21ur-5579 No description available WB:WBGene00166749 21ur-15441 No description available WB:WBGene00166750 21ur-6608 No description available WB:WBGene00166751 21ur-6076 No description available WB:WBGene00166752 21ur-11975 No description available WB:WBGene00166753 21ur-15126 No description available WB:WBGene00166754 21ur-9563 No description available WB:WBGene00166755 21ur-5760 No description available WB:WBGene00166756 21ur-11695 No description available WB:WBGene00166757 21ur-12127 No description available WB:WBGene00166758 21ur-12808 No description available WB:WBGene00166759 21ur-10045 No description available WB:WBGene00166760 21ur-13828 No description available WB:WBGene00166761 21ur-12955 No description available WB:WBGene00166762 21ur-12506 No description available WB:WBGene00166763 21ur-7602 No description available WB:WBGene00166764 21ur-6467 No description available WB:WBGene00166765 21ur-11194 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00166766 21ur-7510 No description available WB:WBGene00166767 21ur-9454 No description available WB:WBGene00166768 21ur-14484 No description available WB:WBGene00166769 21ur-7610 No description available WB:WBGene00166770 21ur-7568 No description available WB:WBGene00166771 21ur-5771 No description available WB:WBGene00166772 21ur-15592 Is affected by daf-2 based on microarray studies. WB:WBGene00166773 21ur-15298 Is affected by emr-1; lem-2; and hmg-3 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00166774 21ur-9399 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00166775 21ur-14870 Is affected by eat-2 based on microarray studies. WB:WBGene00166776 21ur-13306 No description available WB:WBGene00166777 21ur-9123 No description available WB:WBGene00166778 21ur-12011 No description available WB:WBGene00166779 21ur-5611 No description available WB:WBGene00166780 21ur-6105 No description available WB:WBGene00166781 21ur-5883 No description available WB:WBGene00166782 21ur-5456 No description available WB:WBGene00166783 21ur-9070 No description available WB:WBGene00166784 21ur-15659 No description available WB:WBGene00166785 21ur-8681 No description available WB:WBGene00166786 21ur-8039 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00166787 21ur-7564 No description available WB:WBGene00166788 21ur-5521 No description available WB:WBGene00166789 21ur-9376 No description available WB:WBGene00166790 21ur-13929 No description available WB:WBGene00166791 21ur-9542 No description available WB:WBGene00166792 21ur-8897 No description available WB:WBGene00166793 21ur-8725 No description available WB:WBGene00166794 21ur-10828 No description available WB:WBGene00166795 21ur-9900 No description available WB:WBGene00166796 21ur-12747 No description available WB:WBGene00166797 21ur-5649 No description available WB:WBGene00166798 21ur-6831 No description available WB:WBGene00166799 21ur-10152 No description available WB:WBGene00166800 21ur-5748 No description available WB:WBGene00166801 21ur-9782 No description available WB:WBGene00166802 21ur-9754 No description available WB:WBGene00166803 21ur-13805 No description available WB:WBGene00166804 21ur-6566 No description available WB:WBGene00166805 21ur-13795 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00166806 21ur-14799 No description available WB:WBGene00166807 21ur-7950 No description available WB:WBGene00166808 21ur-8466 No description available WB:WBGene00166809 21ur-10278 No description available WB:WBGene00166810 21ur-13750 No description available WB:WBGene00166811 21ur-8662 Enriched in neurons based on RNA-seq studies. WB:WBGene00166812 21ur-7537 No description available WB:WBGene00166813 21ur-15356 Is affected by eat-2 based on microarray studies. WB:WBGene00166814 21ur-10678 No description available WB:WBGene00166815 21ur-7534 No description available WB:WBGene00166816 21ur-14849 No description available WB:WBGene00166817 21ur-9615 No description available WB:WBGene00166819 21ur-6202 No description available WB:WBGene00166820 21ur-13123 No description available WB:WBGene00166821 21ur-14610 No description available WB:WBGene00166822 21ur-7836 No description available WB:WBGene00166823 21ur-10535 No description available WB:WBGene00166824 21ur-14402 No description available WB:WBGene00166825 21ur-11185 No description available WB:WBGene00166826 21ur-7681 No description available WB:WBGene00166827 21ur-6452 No description available WB:WBGene00166828 21ur-13423 No description available WB:WBGene00166829 21ur-14075 No description available WB:WBGene00166830 21ur-11605 No description available WB:WBGene00166831 21ur-8630 No description available WB:WBGene00166832 21ur-13719 No description available WB:WBGene00166833 21ur-7222 No description available WB:WBGene00166834 21ur-15527 No description available WB:WBGene00166835 21ur-9072 No description available WB:WBGene00166836 21ur-5594 No description available WB:WBGene00166837 21ur-12111 No description available WB:WBGene00166838 21ur-5993 No description available WB:WBGene00166839 21ur-6691 No description available WB:WBGene00166840 21ur-11476 No description available WB:WBGene00166841 21ur-7855 Enriched in neurons based on RNA-seq studies. WB:WBGene00166842 21ur-6974 No description available WB:WBGene00166843 21ur-7835 No description available WB:WBGene00166844 21ur-6940 Enriched in neurons based on RNA-seq studies. WB:WBGene00166845 21ur-14156 No description available WB:WBGene00166846 21ur-14058 No description available WB:WBGene00166847 21ur-14636 No description available WB:WBGene00166848 21ur-8179 No description available WB:WBGene00166849 21ur-6485 No description available WB:WBGene00166850 21ur-12718 No description available WB:WBGene00166851 21ur-7942 No description available WB:WBGene00166852 21ur-12491 No description available WB:WBGene00166853 21ur-15652 No description available WB:WBGene00166854 21ur-14923 No description available WB:WBGene00166855 21ur-8939 No description available WB:WBGene00166856 21ur-5528 No description available WB:WBGene00166857 21ur-14238 No description available WB:WBGene00166858 21ur-7226 No description available WB:WBGene00166859 21ur-8732 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00166860 21ur-6796 No description available WB:WBGene00166861 21ur-9170 No description available WB:WBGene00166862 21ur-7559 Enriched in neurons based on RNA-seq studies. WB:WBGene00166863 21ur-12895 No description available WB:WBGene00166864 21ur-6314 No description available WB:WBGene00166865 21ur-13618 No description available WB:WBGene00166866 21ur-11336 No description available WB:WBGene00166867 21ur-10428 No description available WB:WBGene00166868 21ur-15645 No description available WB:WBGene00166869 21ur-11457 No description available WB:WBGene00166870 21ur-14099 No description available WB:WBGene00166871 21ur-11875 No description available WB:WBGene00166872 21ur-9280 No description available WB:WBGene00166873 21ur-9262 No description available WB:WBGene00166874 21ur-9921 No description available WB:WBGene00166875 21ur-9711 No description available WB:WBGene00166876 21ur-12154 No description available WB:WBGene00166877 21ur-11879 No description available WB:WBGene00166878 21ur-9237 No description available WB:WBGene00166879 21ur-7735 No description available WB:WBGene00166880 21ur-13621 No description available WB:WBGene00166881 21ur-8871 No description available WB:WBGene00166882 21ur-14961 No description available WB:WBGene00166883 21ur-12347 No description available WB:WBGene00166884 21ur-7408 No description available WB:WBGene00166885 21ur-11857 Enriched in neurons based on RNA-seq studies. WB:WBGene00166886 21ur-6310 Is affected by set-2 based on RNA-seq studies. WB:WBGene00166887 21ur-6927 No description available WB:WBGene00166888 21ur-15641 No description available WB:WBGene00166889 21ur-8875 No description available WB:WBGene00166890 21ur-5550 No description available WB:WBGene00166891 21ur-7702 No description available WB:WBGene00166892 21ur-7719 No description available WB:WBGene00166893 21ur-8012 No description available WB:WBGene00166894 21ur-15251 No description available WB:WBGene00166895 21ur-7055 No description available WB:WBGene00166896 21ur-5500 No description available WB:WBGene00166897 21ur-12640 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00166898 21ur-11549 No description available WB:WBGene00166899 21ur-10684 No description available WB:WBGene00166900 21ur-6377 No description available WB:WBGene00166901 21ur-8104 No description available WB:WBGene00166902 21ur-11202 No description available WB:WBGene00166903 21ur-9620 No description available WB:WBGene00166904 21ur-10660 No description available WB:WBGene00166905 21ur-10324 No description available WB:WBGene00166906 21ur-11006 No description available WB:WBGene00166907 21ur-10640 No description available WB:WBGene00166908 21ur-12624 No description available WB:WBGene00166909 21ur-12214 No description available WB:WBGene00166910 21ur-6236 No description available WB:WBGene00166911 21ur-15532 No description available WB:WBGene00166912 21ur-11540 No description available WB:WBGene00166913 21ur-8199 No description available WB:WBGene00166914 21ur-6572 No description available WB:WBGene00166915 21ur-13587 No description available WB:WBGene00166916 21ur-9183 No description available WB:WBGene00166917 21ur-15407 No description available WB:WBGene00166918 21ur-8723 No description available WB:WBGene00166919 21ur-11378 No description available WB:WBGene00166920 21ur-12902 No description available WB:WBGene00166921 21ur-6508 Enriched in neurons based on RNA-seq studies. WB:WBGene00166922 21ur-6631 No description available WB:WBGene00166923 21ur-14506 No description available WB:WBGene00166924 21ur-12180 No description available WB:WBGene00166925 21ur-13477 No description available WB:WBGene00166926 21ur-9293 No description available WB:WBGene00166927 21ur-13663 No description available WB:WBGene00166928 21ur-8362 No description available WB:WBGene00166929 21ur-5583 No description available WB:WBGene00166930 21ur-9892 No description available WB:WBGene00166931 21ur-6067 No description available WB:WBGene00166932 21ur-6645 No description available WB:WBGene00166933 21ur-14678 No description available WB:WBGene00166934 21ur-11064 No description available WB:WBGene00166935 21ur-8892 No description available WB:WBGene00166936 21ur-5841 No description available WB:WBGene00166937 21ur-13591 No description available WB:WBGene00166938 21ur-6459 No description available WB:WBGene00166939 21ur-15373 No description available WB:WBGene00166940 21ur-9862 No description available WB:WBGene00166941 21ur-6392 No description available WB:WBGene00166942 21ur-13009 No description available WB:WBGene00166943 21ur-7521 No description available WB:WBGene00166944 21ur-15185 No description available WB:WBGene00166945 21ur-13367 No description available WB:WBGene00166946 21ur-8899 No description available WB:WBGene00166947 21ur-11869 No description available WB:WBGene00166948 21ur-14304 No description available WB:WBGene00166949 21ur-13073 No description available WB:WBGene00166950 21ur-14226 No description available WB:WBGene00166951 21ur-11803 No description available WB:WBGene00166952 21ur-14821 No description available WB:WBGene00166953 21ur-10377 No description available WB:WBGene00166954 21ur-6425 No description available WB:WBGene00166955 21ur-6019 No description available WB:WBGene00166956 21ur-8958 No description available WB:WBGene00166957 21ur-10954 No description available WB:WBGene00166958 21ur-11304 No description available WB:WBGene00166959 21ur-8559 No description available WB:WBGene00166960 21ur-12433 No description available WB:WBGene00166961 21ur-8850 No description available WB:WBGene00166962 21ur-15559 No description available WB:WBGene00166963 21ur-14729 No description available WB:WBGene00166964 21ur-15664 No description available WB:WBGene00166965 21ur-8239 No description available WB:WBGene00166966 21ur-11636 No description available WB:WBGene00166967 21ur-6295 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00166968 21ur-12517 No description available WB:WBGene00166969 21ur-12615 No description available WB:WBGene00166970 21ur-10516 No description available WB:WBGene00166971 21ur-11496 No description available WB:WBGene00166972 21ur-11578 No description available WB:WBGene00166973 21ur-10982 No description available WB:WBGene00166974 21ur-15212 No description available WB:WBGene00166975 21ur-11603 No description available WB:WBGene00166976 21ur-6683 No description available WB:WBGene00166977 21ur-10647 No description available WB:WBGene00166978 21ur-11119 No description available WB:WBGene00166979 21ur-15043 No description available WB:WBGene00166980 21ur-10691 No description available WB:WBGene00166981 21ur-6655 No description available WB:WBGene00166982 21ur-10669 No description available WB:WBGene00166983 21ur-8823 No description available WB:WBGene00166984 21ur-9228 No description available WB:WBGene00166985 21ur-6954 No description available WB:WBGene00166986 21ur-15138 No description available WB:WBGene00166987 21ur-11338 No description available WB:WBGene00166988 21ur-9283 No description available WB:WBGene00166989 21ur-6003 No description available WB:WBGene00166990 21ur-10905 No description available WB:WBGene00166991 21ur-8849 No description available WB:WBGene00166992 21ur-9963 No description available WB:WBGene00166993 21ur-15168 No description available WB:WBGene00166994 21ur-13634 No description available WB:WBGene00166995 21ur-12638 No description available WB:WBGene00166996 21ur-13155 No description available WB:WBGene00166997 21ur-6450 No description available WB:WBGene00166998 21ur-11788 No description available WB:WBGene00166999 21ur-10082 Is affected by set-2 based on RNA-seq studies. WB:WBGene00167000 21ur-8766 No description available WB:WBGene00167001 21ur-7972 No description available WB:WBGene00167002 21ur-10924 No description available WB:WBGene00167003 21ur-7944 No description available WB:WBGene00167004 21ur-11381 No description available WB:WBGene00167005 21ur-6560 No description available WB:WBGene00167006 21ur-15539 No description available WB:WBGene00167007 21ur-14872 No description available WB:WBGene00167008 21ur-13693 No description available WB:WBGene00167009 21ur-15005 Enriched in neurons based on RNA-seq studies. WB:WBGene00167010 21ur-9530 No description available WB:WBGene00167011 21ur-7786 No description available WB:WBGene00167012 21ur-9627 No description available WB:WBGene00167013 21ur-5785 No description available WB:WBGene00167014 21ur-12399 No description available WB:WBGene00167015 21ur-7146 No description available WB:WBGene00167016 21ur-10851 No description available WB:WBGene00167017 21ur-7112 No description available WB:WBGene00167018 21ur-14108 No description available WB:WBGene00167019 21ur-8753 No description available WB:WBGene00167020 21ur-10655 No description available WB:WBGene00167021 21ur-7593 No description available WB:WBGene00167022 21ur-14905 No description available WB:WBGene00167023 21ur-8600 No description available WB:WBGene00167024 21ur-14199 No description available WB:WBGene00167025 21ur-14854 No description available WB:WBGene00167026 21ur-7030 No description available WB:WBGene00167027 21ur-6510 No description available WB:WBGene00167028 21ur-13939 No description available WB:WBGene00167029 21ur-11526 No description available WB:WBGene00167030 21ur-12278 No description available WB:WBGene00167031 21ur-10747 No description available WB:WBGene00167032 21ur-6415 No description available WB:WBGene00167033 21ur-10285 No description available WB:WBGene00167034 21ur-6657 No description available WB:WBGene00167035 21ur-9904 No description available WB:WBGene00167036 21ur-12560 No description available WB:WBGene00167037 21ur-14806 Is affected by emr-1; lem-2; and rnp-6 based on RNA-seq studies. WB:WBGene00167038 21ur-9249 Enriched in neurons based on RNA-seq studies. WB:WBGene00167039 21ur-6620 No description available WB:WBGene00167040 21ur-6296 No description available WB:WBGene00167041 21ur-10393 No description available WB:WBGene00167042 21ur-10818 No description available WB:WBGene00167043 21ur-5936 No description available WB:WBGene00167044 21ur-6381 No description available WB:WBGene00167045 21ur-14190 No description available WB:WBGene00167046 21ur-11128 No description available WB:WBGene00167047 21ur-8333 No description available WB:WBGene00167048 21ur-10892 No description available WB:WBGene00167049 21ur-7690 No description available WB:WBGene00167050 21ur-15267 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00167051 21ur-10740 No description available WB:WBGene00167052 21ur-13146 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00167053 21ur-13298 No description available WB:WBGene00167054 21ur-10400 No description available WB:WBGene00167055 21ur-10866 No description available WB:WBGene00167056 21ur-9157 No description available WB:WBGene00167057 21ur-13700 No description available WB:WBGene00167058 21ur-6730 No description available WB:WBGene00167059 21ur-15282 Is affected by blmp-1 based on RNA-seq studies. WB:WBGene00167060 21ur-15639 No description available WB:WBGene00167061 21ur-8359 No description available WB:WBGene00167062 21ur-8335 No description available WB:WBGene00167063 21ur-15516 No description available WB:WBGene00167064 21ur-12035 No description available WB:WBGene00167065 21ur-9686 No description available WB:WBGene00167066 21ur-12844 No description available WB:WBGene00167067 21ur-11652 No description available WB:WBGene00167068 21ur-8245 No description available WB:WBGene00167069 21ur-6181 No description available WB:WBGene00167070 21ur-6719 No description available WB:WBGene00167071 21ur-15552 No description available WB:WBGene00167072 21ur-14164 No description available WB:WBGene00167073 21ur-8842 No description available WB:WBGene00167074 21ur-11621 Is affected by glycine based on RNA-seq studies. WB:WBGene00167075 21ur-10210 No description available WB:WBGene00167076 21ur-10620 No description available WB:WBGene00167077 21ur-6407 No description available WB:WBGene00167078 21ur-7313 No description available WB:WBGene00167079 21ur-9472 No description available WB:WBGene00167080 21ur-13858 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00167081 21ur-12948 No description available WB:WBGene00167082 21ur-15305 No description available WB:WBGene00167083 21ur-11440 No description available WB:WBGene00167084 21ur-9789 No description available WB:WBGene00167085 21ur-15090 No description available WB:WBGene00167086 21ur-15016 No description available WB:WBGene00167087 21ur-14386 No description available WB:WBGene00167088 21ur-11730 No description available WB:WBGene00167089 21ur-11269 No description available WB:WBGene00167090 21ur-14595 Enriched in neurons based on RNA-seq studies. WB:WBGene00167091 21ur-9134 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00167092 21ur-9139 No description available WB:WBGene00167093 21ur-14511 No description available WB:WBGene00167094 21ur-14318 Enriched in muscle cell based on RNA-seq studies. WB:WBGene00167095 21ur-14101 Is affected by daf-2 based on microarray studies. WB:WBGene00167096 21ur-6343 No description available WB:WBGene00167097 21ur-8398 No description available WB:WBGene00167098 21ur-13890 No description available WB:WBGene00167099 21ur-12423 No description available WB:WBGene00167100 21ur-11898 No description available WB:WBGene00167101 21ur-10469 No description available WB:WBGene00167102 21ur-13457 No description available WB:WBGene00167103 21ur-8785 No description available WB:WBGene00167104 21ur-14867 Is affected by eat-2 based on microarray studies. WB:WBGene00167105 21ur-14515 Enriched in neurons based on RNA-seq studies. WB:WBGene00167106 21ur-13898 No description available WB:WBGene00167107 21ur-13419 No description available WB:WBGene00167108 21ur-13574 No description available WB:WBGene00167109 21ur-7092 No description available WB:WBGene00167110 21ur-9797 No description available WB:WBGene00167111 21ur-14667 No description available WB:WBGene00167112 21ur-13064 No description available WB:WBGene00167113 21ur-14847 No description available WB:WBGene00167114 21ur-9334 No description available WB:WBGene00167115 21ur-6316 No description available WB:WBGene00167116 21ur-9208 No description available WB:WBGene00167117 21ur-8948 No description available WB:WBGene00167118 21ur-6882 No description available WB:WBGene00167119 21ur-11047 No description available WB:WBGene00167120 21ur-14859 No description available WB:WBGene00167121 21ur-14624 No description available WB:WBGene00167122 21ur-5515 No description available WB:WBGene00167123 21ur-15362 No description available WB:WBGene00167124 21ur-9877 No description available WB:WBGene00167125 21ur-11757 No description available WB:WBGene00167126 21ur-10007 No description available WB:WBGene00167127 21ur-11253 No description available WB:WBGene00167128 21ur-6303 No description available WB:WBGene00167129 21ur-15194 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00167130 21ur-15204 No description available WB:WBGene00167131 21ur-12598 No description available WB:WBGene00167132 21ur-7656 No description available WB:WBGene00167133 21ur-11173 No description available WB:WBGene00167134 21ur-5477 No description available WB:WBGene00167135 21ur-7063 No description available WB:WBGene00167136 21ur-12548 No description available WB:WBGene00167137 21ur-10104 No description available WB:WBGene00167138 21ur-10204 No description available WB:WBGene00167139 21ur-8049 No description available WB:WBGene00167140 21ur-8697 No description available WB:WBGene00167141 21ur-10123 No description available WB:WBGene00167142 21ur-9639 No description available WB:WBGene00167143 21ur-6283 No description available WB:WBGene00167144 21ur-10370 No description available WB:WBGene00167145 21ur-13710 No description available WB:WBGene00167146 21ur-9792 No description available WB:WBGene00167147 21ur-8192 Is affected by spr-1 and hda-2 based on RNA-seq studies. WB:WBGene00167148 21ur-5684 No description available WB:WBGene00167149 21ur-10273 No description available WB:WBGene00167150 21ur-9041 No description available WB:WBGene00167151 21ur-7797 No description available WB:WBGene00167152 21ur-7616 No description available WB:WBGene00167153 21ur-7193 No description available WB:WBGene00167154 21ur-13645 No description available WB:WBGene00167155 21ur-15464 No description available WB:WBGene00167156 21ur-9498 No description available WB:WBGene00167157 21ur-7428 No description available WB:WBGene00167158 21ur-14281 Enriched in neurons based on RNA-seq studies. WB:WBGene00167159 21ur-8552 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00167160 21ur-10438 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00167161 21ur-5917 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00167162 21ur-14966 No description available WB:WBGene00167163 21ur-7250 Enriched in neurons based on RNA-seq studies. WB:WBGene00167164 21ur-9308 No description available WB:WBGene00167165 21ur-7708 No description available WB:WBGene00167166 21ur-8064 No description available WB:WBGene00167167 21ur-15123 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00167168 21ur-8386 No description available WB:WBGene00167169 21ur-7037 No description available WB:WBGene00167170 21ur-8454 No description available WB:WBGene00167171 21ur-8260 No description available WB:WBGene00167172 21ur-13981 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00167173 21ur-9392 No description available WB:WBGene00167174 21ur-13542 No description available WB:WBGene00167175 21ur-8269 No description available WB:WBGene00167176 21ur-14665 Enriched in neurons based on RNA-seq studies. WB:WBGene00167177 21ur-9994 No description available WB:WBGene00167178 21ur-10477 No description available WB:WBGene00167179 21ur-9487 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00167180 21ur-14559 No description available WB:WBGene00167181 21ur-13781 No description available WB:WBGene00167182 21ur-13770 No description available WB:WBGene00167183 21ur-7871 No description available WB:WBGene00167184 21ur-7078 No description available WB:WBGene00167185 21ur-14132 No description available WB:WBGene00167186 21ur-8880 No description available WB:WBGene00167187 21ur-11483 No description available WB:WBGene00167188 21ur-11626 No description available WB:WBGene00167189 21ur-11093 No description available WB:WBGene00167190 21ur-8922 No description available WB:WBGene00167191 21ur-13027 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00167192 21ur-14341 No description available WB:WBGene00167193 21ur-15108 No description available WB:WBGene00167194 21ur-8961 No description available WB:WBGene00167195 21ur-13521 No description available WB:WBGene00167196 21ur-6405 No description available WB:WBGene00167197 21ur-10563 No description available WB:WBGene00167198 21ur-5756 No description available WB:WBGene00167199 21ur-7286 No description available WB:WBGene00167200 21ur-14588 No description available WB:WBGene00167201 21ur-15316 No description available WB:WBGene00167202 21ur-7761 No description available WB:WBGene00167203 21ur-14536 No description available WB:WBGene00167204 21ur-7990 No description available WB:WBGene00167205 21ur-11615 No description available WB:WBGene00167206 21ur-10242 No description available WB:WBGene00167207 21ur-9103 No description available WB:WBGene00167208 21ur-6395 No description available WB:WBGene00167209 21ur-12654 No description available WB:WBGene00167210 21ur-11354 No description available WB:WBGene00167211 21ur-12827 No description available WB:WBGene00167212 21ur-12375 No description available WB:WBGene00167213 21ur-10143 No description available WB:WBGene00167214 21ur-15326 No description available WB:WBGene00167215 21ur-6533 No description available WB:WBGene00167216 21ur-9031 No description available WB:WBGene00167217 21ur-8536 No description available WB:WBGene00167218 21ur-5569 No description available WB:WBGene00167219 21ur-6750 No description available WB:WBGene00167220 21ur-14907 No description available WB:WBGene00167221 21ur-12191 No description available WB:WBGene00167222 21ur-6622 No description available WB:WBGene00167223 21ur-6679 Enriched in neurons based on RNA-seq studies. WB:WBGene00167224 21ur-13555 No description available WB:WBGene00167225 21ur-14836 No description available WB:WBGene00167226 21ur-13936 No description available WB:WBGene00167227 21ur-11164 No description available WB:WBGene00167228 21ur-10158 No description available WB:WBGene00167229 21ur-6876 No description available WB:WBGene00167230 21ur-13745 No description available WB:WBGene00167231 21ur-11777 No description available WB:WBGene00167232 21ur-13532 No description available WB:WBGene00167233 21ur-13886 Enriched in neurons based on RNA-seq studies. WB:WBGene00167234 21ur-8701 No description available WB:WBGene00167235 21ur-6145 No description available WB:WBGene00167236 21ur-14188 No description available WB:WBGene00167237 21ur-15676 No description available WB:WBGene00167238 21ur-13819 No description available WB:WBGene00167239 21ur-5466 No description available WB:WBGene00167240 21ur-10013 No description available WB:WBGene00167241 21ur-9418 No description available WB:WBGene00167242 21ur-13483 No description available WB:WBGene00167243 21ur-14816 No description available WB:WBGene00167244 21ur-14785 No description available WB:WBGene00167245 21ur-7441 No description available WB:WBGene00167246 21ur-6893 No description available WB:WBGene00167247 21ur-6529 No description available WB:WBGene00167248 21ur-8929 No description available WB:WBGene00167249 21ur-7829 No description available WB:WBGene00167250 21ur-12572 Is affected by hmg-3; nfki-1; and jmjd-5 based on RNA-seq studies. WB:WBGene00167251 21ur-7238 No description available WB:WBGene00167252 21ur-9327 No description available WB:WBGene00167253 21ur-9896 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00167254 21ur-8818 No description available WB:WBGene00167255 21ur-15162 No description available WB:WBGene00167256 21ur-8070 No description available WB:WBGene00167257 21ur-5692 No description available WB:WBGene00167258 21ur-10969 No description available WB:WBGene00167259 21ur-8673 No description available WB:WBGene00167260 21ur-9145 Enriched in muscle cell based on RNA-seq studies. WB:WBGene00167261 21ur-13510 No description available WB:WBGene00167262 21ur-6523 No description available WB:WBGene00167263 21ur-8019 No description available WB:WBGene00167264 21ur-5706 Enriched in neurons based on RNA-seq studies. WB:WBGene00167265 21ur-15378 No description available WB:WBGene00167266 21ur-14120 No description available WB:WBGene00167267 21ur-9447 No description available WB:WBGene00167268 21ur-11400 No description available WB:WBGene00167269 21ur-12264 Enriched in neurons based on RNA-seq studies. WB:WBGene00167270 21ur-11365 No description available WB:WBGene00167271 21ur-10135 No description available WB:WBGene00167272 21ur-12157 No description available WB:WBGene00167273 21ur-14046 No description available WB:WBGene00167274 21ur-7673 No description available WB:WBGene00167275 21ur-7857 No description available WB:WBGene00167276 21ur-14069 No description available WB:WBGene00167277 21ur-9027 Is affected by daf-2 based on microarray studies. WB:WBGene00167278 21ur-11538 No description available WB:WBGene00167279 21ur-14762 No description available WB:WBGene00167280 21ur-7929 No description available WB:WBGene00167281 21ur-6601 No description available WB:WBGene00167282 21ur-15510 Enriched in AFD based on RNA-seq studies. WB:WBGene00167283 21ur-8184 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00167284 21ur-6744 No description available WB:WBGene00167285 21ur-12694 No description available WB:WBGene00167286 21ur-12451 No description available WB:WBGene00167287 21ur-6511 No description available WB:WBGene00167288 21ur-12207 No description available WB:WBGene00167289 21ur-6219 No description available WB:WBGene00167290 21ur-10712 No description available WB:WBGene00167291 21ur-9446 No description available WB:WBGene00167292 21ur-14944 No description available WB:WBGene00167293 21ur-7695 No description available WB:WBGene00167294 21ur-15321 No description available WB:WBGene00167295 21ur-13341 No description available WB:WBGene00167296 21ur-9261 No description available WB:WBGene00167297 21ur-15032 No description available WB:WBGene00167298 21ur-13204 No description available WB:WBGene00167299 21ur-7850 No description available WB:WBGene00167300 21ur-14379 No description available WB:WBGene00167301 21ur-12773 Enriched in neurons based on RNA-seq studies. WB:WBGene00167302 21ur-6897 No description available WB:WBGene00167303 21ur-11886 No description available WB:WBGene00167304 21ur-15173 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00167305 21ur-9600 No description available WB:WBGene00167306 21ur-6444 Enriched in neurons based on RNA-seq studies. WB:WBGene00167307 21ur-5625 No description available WB:WBGene00167308 21ur-11553 No description available WB:WBGene00167309 21ur-7413 No description available WB:WBGene00167310 21ur-10930 No description available WB:WBGene00167311 21ur-7980 No description available WB:WBGene00167312 21ur-13430 No description available WB:WBGene00167313 21ur-10546 No description available WB:WBGene00167314 21ur-14619 No description available WB:WBGene00167315 21ur-11298 No description available WB:WBGene00167316 21ur-13684 Is affected by spt-16 based on RNA-seq studies. WB:WBGene00167317 21ur-6937 No description available WB:WBGene00167318 21ur-9667 No description available WB:WBGene00167319 21ur-14141 No description available WB:WBGene00167320 21ur-9773 No description available WB:WBGene00167321 21ur-10957 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00167322 21ur-10545 No description available WB:WBGene00167323 21ur-8803 No description available WB:WBGene00167324 21ur-5696 No description available WB:WBGene00167325 21ur-12253 No description available WB:WBGene00167326 21ur-6091 No description available WB:WBGene00167327 21ur-9268 No description available WB:WBGene00167328 21ur-12199 No description available WB:WBGene00167329 21ur-8374 No description available WB:WBGene00167330 21ur-8312 No description available WB:WBGene00167331 21ur-10338 No description available WB:WBGene00167332 21ur-6665 No description available WB:WBGene00167333 21ur-13626 No description available WB:WBGene00167334 21ur-15051 No description available WB:WBGene00167335 21ur-14274 No description available WB:WBGene00167336 21ur-12859 No description available WB:WBGene00167337 21ur-14696 Enriched in neurons based on RNA-seq studies. WB:WBGene00167338 21ur-12795 No description available WB:WBGene00167339 21ur-11423 No description available WB:WBGene00167340 21ur-12558 No description available WB:WBGene00167341 21ur-8828 No description available WB:WBGene00167342 21ur-12143 No description available WB:WBGene00167343 21ur-14546 No description available WB:WBGene00167344 21ur-9932 No description available WB:WBGene00167345 21ur-6278 No description available WB:WBGene00167346 21ur-10385 No description available WB:WBGene00167347 21ur-9999 Enriched in neurons based on RNA-seq studies. WB:WBGene00167348 21ur-5967 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00167349 21ur-11983 No description available WB:WBGene00167350 21ur-6258 No description available WB:WBGene00167351 21ur-6128 No description available WB:WBGene00167352 21ur-5737 No description available WB:WBGene00167353 21ur-6615 No description available WB:WBGene00167354 21ur-13348 No description available WB:WBGene00167355 21ur-15446 No description available WB:WBGene00167356 21ur-6012 No description available WB:WBGene00167357 21ur-11914 No description available WB:WBGene00167358 21ur-9939 Enriched in neurons based on RNA-seq studies. WB:WBGene00167359 21ur-10074 No description available WB:WBGene00167360 21ur-7479 No description available WB:WBGene00167361 21ur-10232 No description available WB:WBGene00167362 21ur-7001 No description available WB:WBGene00167363 21ur-15039 No description available WB:WBGene00167364 21ur-12623 No description available WB:WBGene00167365 21ur-12735 No description available WB:WBGene00167366 21ur-11262 No description available WB:WBGene00167367 21ur-9210 No description available WB:WBGene00167368 21ur-5872 No description available WB:WBGene00167369 21ur-13462 No description available WB:WBGene00167370 21ur-7175 No description available WB:WBGene00167371 21ur-10519 No description available WB:WBGene00167372 21ur-10482 No description available WB:WBGene00167373 21ur-10497 No description available WB:WBGene00167374 21ur-8583 No description available WB:WBGene00167375 21ur-10046 No description available WB:WBGene00167376 21ur-13380 No description available WB:WBGene00167377 21ur-6579 No description available WB:WBGene00167378 21ur-10673 No description available WB:WBGene00167379 21ur-10217 No description available WB:WBGene00167380 21ur-13740 No description available WB:WBGene00167381 21ur-11222 No description available WB:WBGene00167382 21ur-7362 No description available WB:WBGene00167383 21ur-5596 No description available WB:WBGene00167384 21ur-11531 No description available WB:WBGene00167385 21ur-7122 No description available WB:WBGene00167386 21ur-13437 No description available WB:WBGene00167387 21ur-9516 No description available WB:WBGene00167388 21ur-12361 No description available WB:WBGene00167389 21ur-12677 No description available WB:WBGene00167390 21ur-10318 No description available WB:WBGene00167391 21ur-10805 No description available WB:WBGene00167392 21ur-7358 No description available WB:WBGene00167393 21ur-13500 No description available WB:WBGene00167394 21ur-11673 No description available WB:WBGene00167395 21ur-9571 Enriched in neurons based on RNA-seq studies. WB:WBGene00167396 21ur-9757 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00167397 21ur-9093 No description available WB:WBGene00167398 21ur-14336 No description available WB:WBGene00167399 21ur-10698 No description available WB:WBGene00167400 21ur-14459 No description available WB:WBGene00167401 21ur-6567 No description available WB:WBGene00167402 21ur-10364 No description available WB:WBGene00167403 21ur-15392 No description available WB:WBGene00167404 21ur-11393 No description available WB:WBGene00167405 21ur-10917 No description available WB:WBGene00167406 21ur-6886 No description available WB:WBGene00167407 21ur-14655 No description available WB:WBGene00167408 21ur-11712 No description available WB:WBGene00167409 21ur-12126 No description available WB:WBGene00167410 21ur-8151 No description available WB:WBGene00167411 21ur-15501 No description available WB:WBGene00167412 21ur-10111 No description available WB:WBGene00167413 21ur-5731 Is affected by lem-2; emr-1; and rnp-6 based on RNA-seq studies. WB:WBGene00167414 21ur-10249 Enriched in neurons based on RNA-seq studies. Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00167415 21ur-8353 Enriched in neurons based on RNA-seq studies. WB:WBGene00167416 21ur-6853 No description available WB:WBGene00167417 21ur-7353 No description available WB:WBGene00167418 21ur-13549 No description available WB:WBGene00167419 21ur-12005 No description available WB:WBGene00167420 21ur-11780 No description available WB:WBGene00167421 21ur-11324 No description available WB:WBGene00167422 21ur-9706 No description available WB:WBGene00167423 21ur-8109 No description available WB:WBGene00167424 21ur-12908 No description available WB:WBGene00167425 21ur-5662 No description available WB:WBGene00167426 21ur-5559 No description available WB:WBGene00167427 21ur-15098 Enriched in neurons based on RNA-seq studies. WB:WBGene00167428 21ur-13264 No description available WB:WBGene00167429 21ur-10407 No description available WB:WBGene00167430 21ur-15258 No description available WB:WBGene00167431 21ur-10303 No description available WB:WBGene00167432 21ur-7492 No description available WB:WBGene00167433 21ur-15432 No description available WB:WBGene00167434 21ur-14418 No description available WB:WBGene00167435 21ur-12059 No description available WB:WBGene00167436 21ur-6799 No description available WB:WBGene00167437 21ur-7840 No description available WB:WBGene00167438 21ur-13988 No description available WB:WBGene00167439 21ur-15573 No description available WB:WBGene00167440 21ur-15545 Enriched in neurons based on RNA-seq studies. WB:WBGene00167441 21ur-12477 No description available WB:WBGene00167442 21ur-11439 No description available WB:WBGene00167443 21ur-13997 No description available WB:WBGene00167444 21ur-15458 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00167445 21ur-10266 No description available WB:WBGene00167446 21ur-15626 No description available WB:WBGene00167447 21ur-7271 No description available WB:WBGene00167448 21ur-9695 No description available WB:WBGene00167449 21ur-14295 No description available WB:WBGene00167450 21ur-8708 No description available WB:WBGene00167451 21ur-15273 No description available WB:WBGene00167452 21ur-12301 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00167453 21ur-7218 No description available WB:WBGene00167454 21ur-15110 Enriched in neurons based on RNA-seq studies. WB:WBGene00167455 21ur-9526 No description available WB:WBGene00167456 21ur-9150 No description available WB:WBGene00167457 21ur-8968 No description available WB:WBGene00167458 21ur-8999 No description available WB:WBGene00167459 21ur-7528 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00167460 21ur-5552 No description available WB:WBGene00167461 21ur-12083 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00167462 21ur-7106 No description available WB:WBGene00167463 21ur-11432 No description available WB:WBGene00167464 21ur-5846 No description available WB:WBGene00167465 21ur-13657 No description available WB:WBGene00167466 21ur-6036 No description available WB:WBGene00167467 21ur-7634 No description available WB:WBGene00167468 21ur-13812 No description available WB:WBGene00167469 21ur-5985 Enriched in neurons based on RNA-seq studies. WB:WBGene00167470 21ur-12073 No description available WB:WBGene00167471 21ur-5777 No description available WB:WBGene00167472 21ur-11211 No description available WB:WBGene00167473 21ur-12534 No description available WB:WBGene00167474 21ur-8010 No description available WB:WBGene00167475 21ur-10768 No description available WB:WBGene00167476 21ur-13905 No description available WB:WBGene00167477 21ur-15066 No description available WB:WBGene00167478 21ur-13673 No description available WB:WBGene00167479 21ur-8598 No description available WB:WBGene00167480 21ur-8567 No description available WB:WBGene00167481 21ur-6166 No description available WB:WBGene00167482 21ur-13589 No description available WB:WBGene00167483 21ur-5879 No description available WB:WBGene00167484 21ur-7132 No description available WB:WBGene00167485 21ur-7082 No description available WB:WBGene00167487 21ur-14258 No description available WB:WBGene00167488 21ur-11108 No description available WB:WBGene00167489 21ur-10602 No description available WB:WBGene00167490 21ur-7389 No description available WB:WBGene00167491 21ur-12270 No description available WB:WBGene00167492 21ur-9040 No description available WB:WBGene00167493 21ur-7022 No description available WB:WBGene00167494 21ur-6024 No description available WB:WBGene00167495 21ur-7321 No description available WB:WBGene00167496 21ur-9386 No description available WB:WBGene00167497 21ur-7820 No description available WB:WBGene00167498 21ur-6210 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00167499 21ur-6186 No description available WB:WBGene00167500 21ur-11443 No description available WB:WBGene00167501 21ur-5590 No description available WB:WBGene00167502 21ur-7530 No description available WB:WBGene00167503 21ur-14558 No description available WB:WBGene00167504 21ur-6212 No description available WB:WBGene00167505 21ur-14481 No description available WB:WBGene00167506 21ur-12752 Is affected by spt-16 based on RNA-seq studies. WB:WBGene00167507 21ur-13220 Enriched in neurons based on RNA-seq studies. WB:WBGene00167508 21ur-7648 No description available WB:WBGene00167509 21ur-8975 No description available WB:WBGene00167510 21ur-12161 No description available WB:WBGene00167511 21ur-14579 No description available WB:WBGene00167512 21ur-5898 No description available WB:WBGene00167513 21ur-12653 No description available WB:WBGene00167514 21ur-12129 No description available WB:WBGene00167515 21ur-10558 No description available WB:WBGene00167516 21ur-10277 No description available WB:WBGene00167517 21ur-9899 No description available WB:WBGene00167518 21ur-6422 No description available WB:WBGene00167519 21ur-11143 No description available WB:WBGene00167520 21ur-7473 Is affected by daf-2 based on microarray studies. WB:WBGene00167521 21ur-12525 No description available WB:WBGene00167522 21ur-6609 No description available WB:WBGene00167523 21ur-15342 No description available WB:WBGene00167524 21ur-13963 No description available WB:WBGene00167525 21ur-12667 No description available WB:WBGene00167526 21ur-9780 No description available WB:WBGene00167527 21ur-11241 No description available WB:WBGene00167528 21ur-6935 No description available WB:WBGene00167529 21ur-8693 No description available WB:WBGene00167530 21ur-10760 No description available WB:WBGene00167531 21ur-5540 No description available WB:WBGene00167532 21ur-13796 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00167533 21ur-9832 No description available WB:WBGene00167534 21ur-8191 No description available WB:WBGene00167535 21ur-6209 No description available WB:WBGene00167536 21ur-11931 No description available WB:WBGene00167537 21ur-10704 No description available WB:WBGene00167538 21ur-15193 No description available WB:WBGene00167539 21ur-15022 No description available WB:WBGene00167540 21ur-11907 No description available WB:WBGene00167541 21ur-6838 No description available WB:WBGene00167542 21ur-14015 No description available WB:WBGene00167543 21ur-15605 No description available WB:WBGene00167544 21ur-12587 No description available WB:WBGene00167545 21ur-14400 No description available WB:WBGene00167546 21ur-12805 No description available WB:WBGene00167547 21ur-13599 No description available WB:WBGene00167548 21ur-12957 No description available WB:WBGene00167549 21ur-14441 No description available WB:WBGene00167550 21ur-14508 No description available WB:WBGene00167551 21ur-10580 No description available WB:WBGene00167552 21ur-9676 No description available WB:WBGene00167553 21ur-9801 No description available WB:WBGene00167554 21ur-13354 No description available WB:WBGene00167555 21ur-6463 No description available WB:WBGene00167556 21ur-8107 Enriched in AFD based on RNA-seq studies. WB:WBGene00167557 21ur-12116 No description available WB:WBGene00167558 21ur-6197 No description available WB:WBGene00167559 21ur-9250 No description available WB:WBGene00167560 21ur-12817 No description available WB:WBGene00167561 21ur-12313 No description available WB:WBGene00167562 21ur-15634 Enriched in neurons based on RNA-seq studies. WB:WBGene00167563 21ur-11985 No description available WB:WBGene00167564 21ur-6693 No description available WB:WBGene00167565 21ur-5912 No description available WB:WBGene00167566 21ur-15270 No description available WB:WBGene00167567 21ur-13821 No description available WB:WBGene00167568 21ur-8967 No description available WB:WBGene00167569 21ur-10298 No description available WB:WBGene00167570 21ur-8900 No description available WB:WBGene00167571 21ur-14026 No description available WB:WBGene00167572 21ur-8608 No description available WB:WBGene00167573 21ur-6159 No description available WB:WBGene00167574 21ur-5652 No description available WB:WBGene00167575 21ur-7810 No description available WB:WBGene00167576 21ur-15297 No description available WB:WBGene00167577 21ur-8378 Enriched in neurons based on RNA-seq studies. WB:WBGene00167578 21ur-10021 No description available WB:WBGene00167579 21ur-12921 No description available WB:WBGene00167580 21ur-7953 No description available WB:WBGene00167581 21ur-6195 No description available WB:WBGene00167582 21ur-6675 No description available WB:WBGene00167583 21ur-14165 No description available WB:WBGene00167584 21ur-9713 No description available WB:WBGene00167585 21ur-15456 No description available WB:WBGene00167586 21ur-6120 No description available WB:WBGene00167587 21ur-14231 No description available WB:WBGene00167588 21ur-11970 No description available WB:WBGene00167589 21ur-8072 No description available WB:WBGene00167590 21ur-9745 No description available WB:WBGene00167591 21ur-6387 No description available WB:WBGene00167592 21ur-6125 No description available WB:WBGene00167593 21ur-11562 No description available WB:WBGene00167594 21ur-8905 No description available WB:WBGene00167595 21ur-7095 No description available WB:WBGene00167596 21ur-12167 No description available WB:WBGene00167597 21ur-14846 No description available WB:WBGene00167598 21ur-6643 No description available WB:WBGene00167599 21ur-8601 No description available WB:WBGene00167600 21ur-12124 No description available WB:WBGene00167601 21ur-9375 No description available WB:WBGene00167602 21ur-14233 Enriched in neurons based on RNA-seq studies. WB:WBGene00167603 21ur-5458 No description available WB:WBGene00167604 21ur-7513 No description available WB:WBGene00167605 21ur-14933 No description available WB:WBGene00167606 21ur-14074 No description available WB:WBGene00167607 21ur-6071 No description available WB:WBGene00167608 21ur-7152 No description available WB:WBGene00167609 21ur-14056 No description available WB:WBGene00167610 21ur-7557 Enriched in neurons based on RNA-seq studies. WB:WBGene00167611 21ur-7683 No description available WB:WBGene00167612 21ur-14633 No description available WB:WBGene00167613 21ur-9641 No description available WB:WBGene00167614 21ur-7838 No description available WB:WBGene00167615 21ur-14648 No description available WB:WBGene00167616 21ur-11564 No description available WB:WBGene00167617 21ur-11749 No description available WB:WBGene00167618 21ur-6456 No description available WB:WBGene00167619 21ur-12750 No description available WB:WBGene00167620 21ur-6995 No description available WB:WBGene00167621 21ur-5491 No description available WB:WBGene00167622 21ur-9363 No description available WB:WBGene00167623 21ur-8474 No description available WB:WBGene00167624 21ur-11148 No description available WB:WBGene00167625 21ur-13823 No description available WB:WBGene00167626 21ur-12285 No description available WB:WBGene00167627 21ur-11172 No description available WB:WBGene00167628 21ur-7509 No description available WB:WBGene00167629 21ur-14754 No description available WB:WBGene00167630 21ur-13601 No description available WB:WBGene00167631 21ur-12759 No description available WB:WBGene00167632 21ur-8722 No description available WB:WBGene00167633 21ur-7535 No description available WB:WBGene00167634 21ur-12045 No description available WB:WBGene00167635 21ur-14399 No description available WB:WBGene00167636 21ur-5663 No description available WB:WBGene00167637 21ur-13977 No description available WB:WBGene00167638 21ur-6977 No description available WB:WBGene00167639 21ur-8938 No description available WB:WBGene00167640 21ur-10765 No description available WB:WBGene00167641 21ur-9561 No description available WB:WBGene00167642 21ur-6270 No description available WB:WBGene00167643 21ur-14988 No description available WB:WBGene00167644 21ur-7347 No description available WB:WBGene00167645 21ur-14921 No description available WB:WBGene00167646 21ur-15179 No description available WB:WBGene00167647 21ur-14899 No description available WB:WBGene00167648 21ur-13425 Is affected by several genes including daf-16; cpl-1; and blmp-1 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies. WB:WBGene00167649 21ur-7181 No description available WB:WBGene00167650 21ur-5947 No description available WB:WBGene00167651 21ur-6440 No description available WB:WBGene00167652 21ur-14981 No description available WB:WBGene00167653 21ur-12448 No description available WB:WBGene00167654 21ur-11463 No description available WB:WBGene00167655 21ur-9316 No description available WB:WBGene00167656 21ur-14746 No description available WB:WBGene00167657 21ur-11289 No description available WB:WBGene00167658 21ur-10748 No description available WB:WBGene00167659 21ur-8776 No description available WB:WBGene00167660 21ur-12606 No description available WB:WBGene00167661 21ur-6930 No description available WB:WBGene00167662 21ur-8995 No description available WB:WBGene00167663 21ur-14562 No description available WB:WBGene00167664 21ur-7024 Enriched in neurons based on RNA-seq studies. WB:WBGene00167665 21ur-6004 No description available WB:WBGene00167666 21ur-14246 No description available WB:WBGene00167667 21ur-11558 No description available WB:WBGene00167668 21ur-7637 No description available WB:WBGene00167669 21ur-6538 No description available WB:WBGene00167670 21ur-7376 No description available WB:WBGene00167671 21ur-12337 No description available WB:WBGene00167672 21ur-10103 No description available WB:WBGene00167673 21ur-6806 Is affected by lem-2; emr-1; and tdc-1 based on RNA-seq studies. WB:WBGene00167674 21ur-7493 No description available WB:WBGene00167675 21ur-13091 No description available WB:WBGene00167676 21ur-7159 No description available WB:WBGene00167677 21ur-5792 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00167678 21ur-12710 No description available WB:WBGene00167679 21ur-9922 No description available WB:WBGene00167680 21ur-8804 Enriched in neurons based on RNA-seq studies. WB:WBGene00167681 21ur-14431 No description available WB:WBGene00167682 21ur-13287 No description available WB:WBGene00167683 21ur-12744 No description available WB:WBGene00167684 21ur-11072 No description available WB:WBGene00167685 21ur-9174 No description available WB:WBGene00167686 21ur-8667 No description available WB:WBGene00167687 21ur-7843 No description available WB:WBGene00167688 21ur-7817 No description available WB:WBGene00167689 21ur-14772 No description available WB:WBGene00167690 21ur-6332 No description available WB:WBGene00167691 21ur-6943 No description available WB:WBGene00167692 21ur-8164 Enriched in neurons based on RNA-seq studies. WB:WBGene00167693 21ur-5479 No description available WB:WBGene00167694 21ur-12277 No description available WB:WBGene00167695 21ur-6506 No description available WB:WBGene00167696 21ur-8084 No description available WB:WBGene00167697 21ur-9774 No description available WB:WBGene00167698 21ur-12496 No description available WB:WBGene00167699 21ur-5779 No description available WB:WBGene00167700 21ur-14596 No description available WB:WBGene00167701 21ur-13081 No description available WB:WBGene00167702 21ur-7111 No description available WB:WBGene00167703 21ur-11012 No description available WB:WBGene00167704 21ur-12749 No description available WB:WBGene00167705 21ur-13530 No description available WB:WBGene00167706 21ur-7435 No description available WB:WBGene00167707 21ur-13980 No description available WB:WBGene00167708 21ur-6134 No description available WB:WBGene00167709 21ur-11275 No description available WB:WBGene00167710 21ur-9568 Enriched in neurons based on RNA-seq studies. WB:WBGene00167711 21ur-7500 No description available WB:WBGene00167712 21ur-13131 No description available WB:WBGene00167713 21ur-7304 No description available WB:WBGene00167714 21ur-15004 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00167715 21ur-8634 No description available WB:WBGene00167716 21ur-12681 No description available WB:WBGene00167717 21ur-10751 No description available WB:WBGene00167718 21ur-8365 No description available WB:WBGene00167719 21ur-6727 No description available WB:WBGene00167720 21ur-13953 No description available WB:WBGene00167721 21ur-13749 No description available WB:WBGene00167722 21ur-6064 No description available WB:WBGene00167723 21ur-5873 No description available WB:WBGene00167724 21ur-13235 No description available WB:WBGene00167725 21ur-12434 No description available WB:WBGene00167726 21ur-11363 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00167727 21ur-8094 No description available WB:WBGene00167728 21ur-15013 No description available WB:WBGene00167729 21ur-12504 No description available WB:WBGene00167730 21ur-7291 No description available WB:WBGene00167731 21ur-11370 No description available WB:WBGene00167732 21ur-15181 No description available WB:WBGene00167733 21ur-14616 No description available WB:WBGene00167734 21ur-9069 No description available WB:WBGene00167735 21ur-14993 Enriched in neurons based on RNA-seq studies. WB:WBGene00167736 21ur-8356 No description available WB:WBGene00167737 21ur-12915 No description available WB:WBGene00167738 21ur-13147 No description available WB:WBGene00167739 21ur-11405 No description available WB:WBGene00167740 21ur-10571 No description available WB:WBGene00167741 21ur-9982 Enriched in AFD based on RNA-seq studies. WB:WBGene00167742 21ur-9455 No description available WB:WBGene00167743 21ur-9884 No description available WB:WBGene00167744 21ur-6759 No description available WB:WBGene00167745 21ur-7264 No description available WB:WBGene00167746 21ur-7283 No description available WB:WBGene00167747 21ur-10224 No description available WB:WBGene00167748 21ur-7269 No description available WB:WBGene00167749 21ur-5784 No description available WB:WBGene00167750 21ur-11122 No description available WB:WBGene00167751 21ur-11137 No description available WB:WBGene00167752 21ur-14943 No description available WB:WBGene00167753 21ur-14288 No description available WB:WBGene00167754 21ur-11954 No description available WB:WBGene00167755 21ur-9880 No description available WB:WBGene00167756 21ur-14000 No description available WB:WBGene00167757 21ur-11192 No description available WB:WBGene00167758 21ur-14686 Is affected by set-2 based on RNA-seq studies. WB:WBGene00167759 21ur-11977 No description available WB:WBGene00167760 21ur-14571 No description available WB:WBGene00167761 21ur-10262 No description available WB:WBGene00167762 21ur-7908 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00167763 21ur-12101 No description available WB:WBGene00167764 21ur-5889 No description available WB:WBGene00167765 21ur-6498 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00167766 21ur-7893 No description available WB:WBGene00167767 21ur-12484 No description available WB:WBGene00167768 21ur-5802 No description available WB:WBGene00167769 21ur-8910 No description available WB:WBGene00167770 21ur-9727 No description available WB:WBGene00167771 21ur-6824 No description available WB:WBGene00167772 21ur-9311 No description available WB:WBGene00167773 21ur-10705 No description available WB:WBGene00167774 21ur-10358 No description available WB:WBGene00167775 21ur-6554 No description available WB:WBGene00167776 21ur-11377 No description available WB:WBGene00167777 21ur-8686 No description available WB:WBGene00167778 21ur-7746 No description available WB:WBGene00167779 21ur-12464 No description available WB:WBGene00167780 21ur-10175 No description available WB:WBGene00167781 21ur-15684 No description available WB:WBGene00167782 21ur-7083 No description available WB:WBGene00167783 21ur-14377 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00167784 21ur-14170 No description available WB:WBGene00167785 21ur-10155 No description available WB:WBGene00167786 21ur-9657 No description available WB:WBGene00167787 21ur-15353 No description available WB:WBGene00167788 21ur-11412 No description available WB:WBGene00167789 21ur-11995 No description available WB:WBGene00167790 21ur-8161 No description available WB:WBGene00167791 21ur-6084 No description available WB:WBGene00167792 21ur-8324 No description available WB:WBGene00167793 21ur-13346 Enriched in neurons based on RNA-seq studies. WB:WBGene00167794 21ur-9878 No description available WB:WBGene00167795 21ur-6914 No description available WB:WBGene00167796 21ur-7184 No description available WB:WBGene00167797 21ur-7754 No description available WB:WBGene00167799 21ur-6174 No description available WB:WBGene00167800 21ur-7605 No description available WB:WBGene00167801 21ur-8277 No description available WB:WBGene00167802 21ur-10894 No description available WB:WBGene00167803 21ur-9474 No description available WB:WBGene00167804 21ur-10420 Is affected by cpl-1 based on RNA-seq studies. WB:WBGene00167805 21ur-6269 No description available WB:WBGene00167806 21ur-8118 No description available WB:WBGene00167807 21ur-15069 No description available WB:WBGene00167808 21ur-12793 No description available WB:WBGene00167809 21ur-7262 No description available WB:WBGene00167810 21ur-14865 No description available WB:WBGene00167811 21ur-13758 No description available WB:WBGene00167812 21ur-7914 Enriched in neurons based on RNA-seq studies. WB:WBGene00167813 21ur-13815 No description available WB:WBGene00167814 21ur-10446 Enriched in neurons based on RNA-seq studies. WB:WBGene00167815 21ur-8729 No description available WB:WBGene00167816 21ur-8225 No description available WB:WBGene00167817 21ur-12104 No description available WB:WBGene00167818 21ur-9256 No description available WB:WBGene00167819 21ur-13491 No description available WB:WBGene00167820 21ur-10882 Is affected by lem-2; emr-1; and mrps-5 based on RNA-seq studies. WB:WBGene00167821 21ur-14735 No description available WB:WBGene00167822 21ur-12937 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00167823 21ur-12092 No description available WB:WBGene00167824 21ur-9839 No description available WB:WBGene00167825 21ur-6602 No description available WB:WBGene00167826 21ur-14039 No description available WB:WBGene00167827 21ur-11972 No description available WB:WBGene00167828 21ur-10449 No description available WB:WBGene00167829 21ur-9608 No description available WB:WBGene00167830 21ur-10871 No description available WB:WBGene00167831 21ur-7040 No description available WB:WBGene00167832 21ur-12017 No description available WB:WBGene00167833 21ur-12541 No description available WB:WBGene00167834 21ur-13464 No description available WB:WBGene00167835 21ur-14045 No description available WB:WBGene00167836 21ur-12177 No description available WB:WBGene00167837 21ur-9133 No description available WB:WBGene00167838 21ur-5845 No description available WB:WBGene00167839 21ur-9816 No description available WB:WBGene00167840 21ur-9895 No description available WB:WBGene00167841 21ur-8432 No description available WB:WBGene00167842 21ur-14976 No description available WB:WBGene00167843 21ur-11347 No description available WB:WBGene00167845 21ur-9737 No description available WB:WBGene00167846 21ur-13861 No description available WB:WBGene00167847 21ur-9684 No description available WB:WBGene00167848 21ur-13470 No description available WB:WBGene00167849 21ur-6847 No description available WB:WBGene00167850 21ur-9929 Enriched in neurons based on RNA-seq studies. WB:WBGene00167851 21ur-11115 No description available WB:WBGene00167852 21ur-10526 No description available WB:WBGene00167853 21ur-7667 No description available WB:WBGene00167854 21ur-9855 No description available WB:WBGene00167855 21ur-14707 No description available WB:WBGene00167856 21ur-14602 No description available WB:WBGene00167857 21ur-12414 No description available WB:WBGene00167858 21ur-12228 No description available WB:WBGene00167859 21ur-8403 No description available WB:WBGene00167860 21ur-7749 No description available WB:WBGene00167861 21ur-9226 No description available WB:WBGene00167862 21ur-6788 No description available WB:WBGene00167863 21ur-12666 No description available WB:WBGene00167864 21ur-9853 No description available WB:WBGene00167865 21ur-12649 No description available WB:WBGene00167866 21ur-12094 No description available WB:WBGene00167867 21ur-14218 No description available WB:WBGene00167868 21ur-6345 No description available WB:WBGene00167869 21ur-7025 No description available WB:WBGene00167870 21ur-13543 No description available WB:WBGene00167871 21ur-9610 No description available WB:WBGene00167872 21ur-8563 No description available WB:WBGene00167873 21ur-13047 No description available WB:WBGene00167874 21ur-7248 No description available WB:WBGene00167875 21ur-14053 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00167876 21ur-15668 No description available WB:WBGene00167877 21ur-13167 No description available WB:WBGene00167878 21ur-15415 No description available WB:WBGene00167879 21ur-13271 No description available WB:WBGene00167880 21ur-14957 No description available WB:WBGene00167881 21ur-13834 No description available WB:WBGene00167882 21ur-7768 No description available WB:WBGene00167883 21ur-12323 No description available WB:WBGene00167884 21ur-8798 No description available WB:WBGene00167885 21ur-10413 No description available WB:WBGene00167886 21ur-10990 No description available WB:WBGene00167887 21ur-10168 No description available WB:WBGene00167888 21ur-8280 No description available WB:WBGene00167889 21ur-5484 No description available WB:WBGene00167890 21ur-13809 No description available WB:WBGene00167891 21ur-12493 No description available WB:WBGene00167892 21ur-12985 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00167893 21ur-8210 Enriched in neurons based on RNA-seq studies. WB:WBGene00167894 21ur-9576 No description available WB:WBGene00167895 21ur-5603 Enriched in neurons based on RNA-seq studies. WB:WBGene00167896 21ur-10349 No description available WB:WBGene00167897 21ur-13198 No description available WB:WBGene00167898 21ur-15264 No description available WB:WBGene00167899 21ur-6531 No description available WB:WBGene00167900 21ur-12386 No description available WB:WBGene00167901 21ur-11481 No description available WB:WBGene00167902 21ur-9992 No description available WB:WBGene00167903 21ur-7298 No description available WB:WBGene00167904 21ur-8595 No description available WB:WBGene00167905 21ur-10776 No description available WB:WBGene00167906 21ur-11948 No description available WB:WBGene00167907 21ur-8305 No description available WB:WBGene00167908 21ur-10233 No description available WB:WBGene00167909 21ur-15144 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00167910 21ur-13161 No description available WB:WBGene00167911 21ur-14409 No description available WB:WBGene00167912 21ur-15477 No description available WB:WBGene00167913 21ur-14876 No description available WB:WBGene00167914 21ur-14470 No description available WB:WBGene00167915 21ur-15454 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00167916 21ur-14280 No description available WB:WBGene00167917 21ur-8672 No description available WB:WBGene00167918 21ur-9195 No description available WB:WBGene00167919 21ur-11328 No description available WB:WBGene00167920 21ur-7200 No description available WB:WBGene00167921 21ur-9546 No description available WB:WBGene00167922 21ur-5571 No description available WB:WBGene00167923 21ur-7207 No description available WB:WBGene00167924 21ur-10479 No description available WB:WBGene00167925 21ur-11158 No description available WB:WBGene00167926 21ur-14207 No description available WB:WBGene00167927 21ur-7462 No description available WB:WBGene00167928 21ur-7336 No description available WB:WBGene00167929 21ur-11334 No description available WB:WBGene00167930 21ur-9074 No description available WB:WBGene00167931 21ur-12502 No description available WB:WBGene00167932 21ur-11321 No description available WB:WBGene00167933 21ur-10078 No description available WB:WBGene00167934 21ur-9424 No description available WB:WBGene00167935 21ur-7801 No description available WB:WBGene00167936 21ur-15561 No description available WB:WBGene00167937 21ur-11478 No description available WB:WBGene00167938 21ur-6798 No description available WB:WBGene00167939 21ur-11154 No description available WB:WBGene00167940 21ur-10060 No description available WB:WBGene00167941 21ur-8008 No description available WB:WBGene00167942 21ur-14250 No description available WB:WBGene00167943 21ur-5864 No description available WB:WBGene00167944 21ur-14477 No description available WB:WBGene00167945 21ur-8711 No description available WB:WBGene00167946 21ur-14466 No description available WB:WBGene00167947 21ur-12728 No description available WB:WBGene00167948 21ur-7416 No description available WB:WBGene00167949 21ur-13428 Enriched in neurons based on RNA-seq studies. WB:WBGene00167950 21ur-11180 No description available WB:WBGene00167951 21ur-14262 No description available WB:WBGene00167952 21ur-5803 No description available WB:WBGene00167953 21ur-12626 No description available WB:WBGene00167954 21ur-11689 No description available WB:WBGene00167955 21ur-15661 No description available WB:WBGene00167956 21ur-15574 No description available WB:WBGene00167957 21ur-12237 No description available WB:WBGene00167958 21ur-14387 Enriched in neurons based on RNA-seq studies. WB:WBGene00167959 21ur-14784 No description available WB:WBGene00167960 21ur-14456 No description available WB:WBGene00167961 21ur-6305 No description available WB:WBGene00167962 21ur-15530 No description available WB:WBGene00167963 21ur-8176 No description available WB:WBGene00167964 21ur-15358 No description available WB:WBGene00167965 21ur-13729 No description available WB:WBGene00167966 21ur-8207 No description available WB:WBGene00167967 21ur-6702 No description available WB:WBGene00167968 21ur-6052 No description available WB:WBGene00167969 21ur-9358 No description available WB:WBGene00167970 21ur-13008 No description available WB:WBGene00167971 21ur-11859 No description available WB:WBGene00167972 21ur-6039 No description available WB:WBGene00167973 21ur-9189 No description available WB:WBGene00167974 21ur-6842 No description available WB:WBGene00167975 21ur-6049 No description available WB:WBGene00167976 21ur-11581 No description available WB:WBGene00167977 21ur-6435 No description available WB:WBGene00167978 21ur-7318 No description available WB:WBGene00167979 21ur-12336 No description available WB:WBGene00167980 21ur-6670 No description available WB:WBGene00167981 21ur-14424 No description available WB:WBGene00167982 21ur-15699 No description available WB:WBGene00167983 21ur-10737 No description available WB:WBGene00167984 21ur-10502 No description available WB:WBGene00167985 21ur-10126 No description available WB:WBGene00167986 21ur-5955 No description available WB:WBGene00167987 21ur-6451 No description available WB:WBGene00167988 21ur-14716 No description available WB:WBGene00167989 21ur-14032 No description available WB:WBGene00167990 21ur-10662 No description available WB:WBGene00167991 21ur-5921 No description available WB:WBGene00167992 21ur-6035 No description available WB:WBGene00167993 21ur-7549 No description available WB:WBGene00167994 21ur-14917 No description available WB:WBGene00167995 21ur-8514 No description available WB:WBGene00167996 21ur-9527 No description available WB:WBGene00167997 21ur-12533 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00167998 21ur-10410 No description available WB:WBGene00167999 21ur-10035 No description available WB:WBGene00168000 21ur-10198 No description available WB:WBGene00168001 21ur-8420 No description available WB:WBGene00168002 21ur-8091 No description available WB:WBGene00168003 21ur-6247 No description available WB:WBGene00168004 21ur-7864 No description available WB:WBGene00168005 21ur-14937 No description available WB:WBGene00168006 21ur-13849 No description available WB:WBGene00168007 21ur-5474 No description available WB:WBGene00168008 21ur-12791 No description available WB:WBGene00168009 21ur-10952 No description available WB:WBGene00168010 21ur-13228 No description available WB:WBGene00168011 21ur-12810 No description available WB:WBGene00168012 21ur-11079 No description available WB:WBGene00168013 21ur-6883 No description available WB:WBGene00168014 21ur-14563 No description available WB:WBGene00168015 21ur-13842 No description available WB:WBGene00168016 21ur-5688 No description available WB:WBGene00168017 21ur-13099 No description available WB:WBGene00168018 21ur-12944 Enriched in neurons based on RNA-seq studies. WB:WBGene00168019 21ur-11682 No description available WB:WBGene00168020 21ur-9646 No description available WB:WBGene00168021 21ur-6682 No description available WB:WBGene00168022 21ur-13054 No description available WB:WBGene00168023 21ur-6023 No description available WB:WBGene00168024 21ur-13564 No description available WB:WBGene00168025 21ur-15421 No description available WB:WBGene00168026 21ur-11525 No description available WB:WBGene00168027 21ur-9062 No description available WB:WBGene00168028 21ur-12294 Enriched in neurons based on RNA-seq studies. WB:WBGene00168029 21ur-10723 No description available WB:WBGene00168030 21ur-7109 No description available WB:WBGene00168031 21ur-8743 No description available WB:WBGene00168032 21ur-14749 No description available WB:WBGene00168033 21ur-6816 No description available WB:WBGene00168034 21ur-8985 No description available WB:WBGene00168035 21ur-9115 No description available WB:WBGene00168036 21ur-10792 No description available WB:WBGene00168037 21ur-14364 No description available WB:WBGene00168038 21ur-12065 No description available WB:WBGene00168039 21ur-12309 No description available WB:WBGene00168040 21ur-15416 No description available WB:WBGene00168041 21ur-13209 No description available WB:WBGene00168042 21ur-13082 No description available WB:WBGene00168043 21ur-5631 No description available WB:WBGene00168044 21ur-13924 No description available WB:WBGene00168045 21ur-9192 No description available WB:WBGene00168046 21ur-6791 Is affected by daf-2 based on microarray studies. WB:WBGene00168047 21ur-14443 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00168048 21ur-14321 No description available WB:WBGene00168049 21ur-8422 Is affected by nfki-1 and etr-1 based on RNA-seq studies. WB:WBGene00168050 21ur-15219 No description available WB:WBGene00168051 21ur-12409 No description available WB:WBGene00168052 21ur-6262 No description available WB:WBGene00168053 21ur-6096 No description available WB:WBGene00168054 21ur-9972 No description available WB:WBGene00168055 21ur-8622 No description available WB:WBGene00168056 21ur-15409 No description available WB:WBGene00168057 21ur-13479 No description available WB:WBGene00168058 21ur-12312 No description available WB:WBGene00168059 21ur-10492 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00168060 21ur-5835 No description available WB:WBGene00168061 21ur-5810 No description available WB:WBGene00168062 21ur-6491 No description available WB:WBGene00168063 21ur-13170 No description available WB:WBGene00168064 21ur-11187 No description available WB:WBGene00168065 21ur-10215 Is affected by hmg-3; blmp-1; and cpl-1 based on RNA-seq studies. WB:WBGene00168066 21ur-6237 No description available WB:WBGene00168067 21ur-13664 No description available WB:WBGene00168068 21ur-9599 Is affected by several genes including eat-2; lem-2; and emr-1 based on RNA-seq studies. Is affected by cholesterol based on RNA-seq studies. WB:WBGene00168069 21ur-14185 No description available WB:WBGene00168070 21ur-5638 No description available WB:WBGene00168071 21ur-14119 No description available WB:WBGene00168072 21ur-12580 No description available WB:WBGene00168073 21ur-10067 No description available WB:WBGene00168074 21ur-10832 No description available WB:WBGene00168075 21ur-15537 No description available WB:WBGene00168076 21ur-14600 No description available WB:WBGene00168077 21ur-9825 No description available WB:WBGene00168078 21ur-15239 No description available WB:WBGene00168079 21ur-12737 No description available WB:WBGene00168080 21ur-15249 No description available WB:WBGene00168081 21ur-13320 No description available WB:WBGene00168082 21ur-7876 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00168083 21ur-10053 No description available WB:WBGene00168084 21ur-7483 No description available WB:WBGene00168085 21ur-15581 No description available WB:WBGene00168086 21ur-15609 No description available WB:WBGene00168087 21ur-5940 No description available WB:WBGene00168088 21ur-8128 No description available WB:WBGene00168089 21ur-5767 No description available WB:WBGene00168090 21ur-9535 No description available WB:WBGene00168091 21ur-11926 No description available WB:WBGene00168092 21ur-8837 No description available WB:WBGene00168093 21ur-14777 No description available WB:WBGene00168094 21ur-12440 No description available WB:WBGene00168095 21ur-5607 Is affected by eat-2 based on microarray studies. WB:WBGene00168096 21ur-9215 No description available WB:WBGene00168097 21ur-14307 No description available WB:WBGene00168098 21ur-7652 No description available WB:WBGene00168099 21ur-10095 No description available WB:WBGene00168100 21ur-6571 No description available WB:WBGene00168101 21ur-9304 No description available WB:WBGene00168102 21ur-6324 No description available WB:WBGene00168103 21ur-8174 No description available WB:WBGene00168104 21ur-14215 No description available WB:WBGene00168105 21ur-12108 No description available WB:WBGene00168106 21ur-15391 No description available WB:WBGene00168107 21ur-6469 No description available WB:WBGene00168108 21ur-12600 No description available WB:WBGene00168109 21ur-15230 No description available WB:WBGene00168110 21ur-9341 No description available WB:WBGene00168111 21ur-7713 No description available WB:WBGene00168112 21ur-13366 No description available WB:WBGene00168113 21ur-7069 No description available WB:WBGene00168114 21ur-14656 No description available WB:WBGene00168115 21ur-11664 No description available WB:WBGene00168116 21ur-9868 No description available WB:WBGene00168117 21ur-5815 No description available WB:WBGene00168118 21ur-13734 No description available WB:WBGene00168119 21ur-13197 No description available WB:WBGene00168120 21ur-11825 Enriched in neurons based on RNA-seq studies. WB:WBGene00168121 21ur-9953 Is affected by eat-2 based on microarray studies. WB:WBGene00168122 21ur-11248 No description available WB:WBGene00168123 21ur-10783 No description available WB:WBGene00168124 21ur-13412 No description available WB:WBGene00168125 21ur-13213 No description available WB:WBGene00168126 21ur-14179 No description available WB:WBGene00168127 21ur-8830 No description available WB:WBGene00168128 21ur-15426 No description available WB:WBGene00168129 21ur-13234 No description available WB:WBGene00168130 21ur-12348 Is affected by unc-30 based on RNA-seq studies. WB:WBGene00168131 21ur-6146 No description available WB:WBGene00168132 21ur-14884 No description available WB:WBGene00168133 21ur-5980 No description available WB:WBGene00168134 21ur-12850 No description available WB:WBGene00168135 21ur-15256 No description available WB:WBGene00168136 21ur-13717 No description available WB:WBGene00168137 21ur-7288 No description available WB:WBGene00168138 21ur-13628 No description available WB:WBGene00168139 21ur-12746 No description available WB:WBGene00168140 21ur-5509 No description available WB:WBGene00168141 21ur-8791 No description available WB:WBGene00168142 21ur-14458 No description available WB:WBGene00168143 21ur-14252 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00168144 21ur-10807 No description available WB:WBGene00168145 21ur-10485 No description available WB:WBGene00168146 21ur-15178 No description available WB:WBGene00168147 21ur-12772 Enriched in neurons based on RNA-seq studies. WB:WBGene00168148 21ur-11714 No description available WB:WBGene00168149 21ur-9125 No description available WB:WBGene00168150 21ur-15289 No description available WB:WBGene00168151 21ur-8952 No description available WB:WBGene00168152 21ur-14627 No description available WB:WBGene00168153 21ur-10362 No description available WB:WBGene00168154 21ur-5745 No description available WB:WBGene00168155 21ur-11431 No description available WB:WBGene00168156 21ur-11703 No description available WB:WBGene00168157 21ur-13114 No description available WB:WBGene00168158 21ur-10959 No description available WB:WBGene00168159 21ur-11296 Enriched in neurons based on RNA-seq studies. WB:WBGene00168160 21ur-9753 No description available WB:WBGene00168161 21ur-10913 No description available WB:WBGene00168162 21ur-11912 No description available WB:WBGene00168163 21ur-9159 No description available WB:WBGene00168164 21ur-6996 No description available WB:WBGene00168165 21ur-13675 No description available WB:WBGene00168166 21ur-9518 No description available WB:WBGene00168167 21ur-14915 No description available WB:WBGene00168168 21ur-6476 No description available WB:WBGene00168169 21ur-10509 No description available WB:WBGene00168170 21ur-7412 No description available WB:WBGene00168171 21ur-10672 No description available WB:WBGene00168172 21ur-7866 No description available WB:WBGene00168173 21ur-13655 No description available WB:WBGene00168174 21ur-10511 No description available WB:WBGene00168175 21ur-11237 No description available WB:WBGene00168176 21ur-9168 No description available WB:WBGene00168177 21ur-10908 No description available WB:WBGene00168178 21ur-12846 No description available WB:WBGene00168179 21ur-11395 No description available WB:WBGene00168180 21ur-11837 Enriched in neurons based on RNA-seq studies. WB:WBGene00168181 21ur-6968 No description available WB:WBGene00168182 21ur-13804 No description available WB:WBGene00168183 21ur-8585 No description available WB:WBGene00168184 21ur-15111 No description available WB:WBGene00168185 21ur-6545 No description available WB:WBGene00168186 21ur-14635 No description available WB:WBGene00168187 21ur-13357 No description available WB:WBGene00168188 21ur-5987 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00168189 21ur-5969 No description available WB:WBGene00168190 21ur-12904 No description available WB:WBGene00168191 21ur-9746 No description available WB:WBGene00168192 21ur-7354 No description available WB:WBGene00168193 21ur-7547 No description available WB:WBGene00168194 21ur-15092 No description available WB:WBGene00168195 21ur-7401 No description available WB:WBGene00168196 21ur-9396 No description available WB:WBGene00168197 21ur-14675 No description available WB:WBGene00168198 21ur-12942 No description available WB:WBGene00168199 21ur-14360 No description available WB:WBGene00168200 21ur-6822 No description available WB:WBGene00168201 21ur-11394 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00168202 21ur-12367 No description available WB:WBGene00168203 21ur-10713 Enriched in neurons based on RNA-seq studies. WB:WBGene00168204 21ur-8042 No description available WB:WBGene00168205 21ur-8946 No description available WB:WBGene00168206 21ur-12679 No description available WB:WBGene00168207 21ur-5623 No description available WB:WBGene00168208 21ur-11850 No description available WB:WBGene00168209 21ur-13021 Enriched in neurons based on RNA-seq studies. WB:WBGene00168210 21ur-10945 No description available WB:WBGene00168211 21ur-8629 No description available WB:WBGene00168212 21ur-15240 No description available WB:WBGene00168213 21ur-8656 No description available WB:WBGene00168214 21ur-14714 No description available WB:WBGene00168215 21ur-8983 No description available WB:WBGene00168216 21ur-9663 No description available WB:WBGene00168217 21ur-15037 No description available WB:WBGene00168218 21ur-10368 No description available WB:WBGene00168219 21ur-5999 No description available WB:WBGene00168220 21ur-7845 No description available WB:WBGene00168221 21ur-8057 No description available WB:WBGene00168222 21ur-13945 No description available WB:WBGene00168223 21ur-15280 No description available WB:WBGene00168224 21ur-13343 No description available WB:WBGene00168225 21ur-11797 Is affected by pgrn-1 and mrps-5 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00168226 21ur-11533 No description available WB:WBGene00168227 21ur-5538 No description available WB:WBGene00168228 21ur-14532 No description available WB:WBGene00168229 21ur-13382 No description available WB:WBGene00168230 21ur-12837 No description available WB:WBGene00168231 21ur-11509 No description available WB:WBGene00168232 21ur-9651 No description available WB:WBGene00168233 21ur-7120 No description available WB:WBGene00168234 21ur-15145 No description available WB:WBGene00168235 21ur-9161 No description available WB:WBGene00168236 21ur-7363 No description available WB:WBGene00168237 21ur-6761 No description available WB:WBGene00168238 21ur-10344 No description available WB:WBGene00168239 21ur-9046 No description available WB:WBGene00168240 21ur-12393 No description available WB:WBGene00168241 21ur-15063 No description available WB:WBGene00168242 21ur-6447 No description available WB:WBGene00168243 21ur-15663 No description available WB:WBGene00168244 21ur-8037 No description available WB:WBGene00168245 21ur-13876 No description available WB:WBGene00168246 21ur-13991 No description available WB:WBGene00168247 21ur-14271 No description available WB:WBGene00168248 21ur-5960 No description available WB:WBGene00168249 21ur-11161 No description available WB:WBGene00168250 21ur-14974 No description available WB:WBGene00168251 21ur-12596 No description available WB:WBGene00168252 21ur-6275 No description available WB:WBGene00168253 21ur-7767 No description available WB:WBGene00168254 21ur-6878 No description available WB:WBGene00168255 21ur-8350 No description available WB:WBGene00168256 21ur-15312 No description available WB:WBGene00168257 21ur-13431 No description available WB:WBGene00168258 21ur-10461 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00168259 21ur-12789 Enriched in neurons based on RNA-seq studies. WB:WBGene00168260 21ur-11518 No description available WB:WBGene00168261 21ur-8157 No description available WB:WBGene00168262 21ur-8679 Enriched in neurons based on RNA-seq studies. WB:WBGene00168263 21ur-12159 No description available WB:WBGene00168264 21ur-5848 No description available WB:WBGene00168265 21ur-11168 No description available WB:WBGene00168266 21ur-8310 No description available WB:WBGene00168267 21ur-12531 No description available WB:WBGene00168268 21ur-11080 No description available WB:WBGene00168269 21ur-7985 No description available WB:WBGene00168270 21ur-11676 No description available WB:WBGene00168271 21ur-15226 No description available WB:WBGene00168272 21ur-9506 No description available WB:WBGene00168273 21ur-9944 No description available WB:WBGene00168274 21ur-9603 No description available WB:WBGene00168275 21ur-14663 Is affected by met-2 based on RNA-seq studies. WB:WBGene00168276 21ur-11106 No description available WB:WBGene00168277 21ur-10915 No description available WB:WBGene00168278 21ur-9090 No description available WB:WBGene00168279 21ur-6360 No description available WB:WBGene00168280 21ur-6739 No description available WB:WBGene00168281 21ur-11823 No description available WB:WBGene00168282 21ur-5975 No description available WB:WBGene00168283 21ur-11430 No description available WB:WBGene00168284 21ur-10577 No description available WB:WBGene00168285 21ur-7968 No description available WB:WBGene00168286 21ur-11087 No description available WB:WBGene00168287 21ur-6802 No description available WB:WBGene00168288 21ur-6252 No description available WB:WBGene00168289 21ur-6858 No description available WB:WBGene00168290 21ur-5561 No description available WB:WBGene00168291 21ur-10014 No description available WB:WBGene00168292 21ur-13513 No description available WB:WBGene00168293 21ur-12190 No description available WB:WBGene00168294 21ur-8882 No description available WB:WBGene00168295 21ur-6891 No description available WB:WBGene00168296 21ur-13103 No description available WB:WBGene00168297 21ur-12205 No description available WB:WBGene00168298 21ur-7100 No description available WB:WBGene00168299 21ur-14359 No description available WB:WBGene00168300 21ur-10682 No description available WB:WBGene00168301 21ur-9674 No description available WB:WBGene00168302 21ur-7215 No description available WB:WBGene00168303 21ur-13612 No description available WB:WBGene00168304 21ur-10305 No description available WB:WBGene00168305 21ur-6677 Enriched in neurons based on RNA-seq studies. WB:WBGene00168306 21ur-8384 No description available WB:WBGene00168307 21ur-15690 No description available WB:WBGene00168308 21ur-5703 No description available WB:WBGene00168309 21ur-7278 No description available WB:WBGene00168310 21ur-9009 No description available WB:WBGene00168311 21ur-15438 No description available WB:WBGene00168312 21ur-14946 No description available WB:WBGene00168313 21ur-8102 No description available WB:WBGene00168314 21ur-13256 No description available WB:WBGene00168315 21ur-6081 No description available WB:WBGene00168316 21ur-8460 No description available WB:WBGene00168317 21ur-10331 No description available WB:WBGene00168318 21ur-5460 No description available WB:WBGene00168319 21ur-7383 No description available WB:WBGene00168320 21ur-8364 No description available WB:WBGene00168321 21ur-8287 No description available WB:WBGene00168322 21ur-12780 Enriched in neurons based on RNA-seq studies. WB:WBGene00168323 21ur-12360 No description available WB:WBGene00168324 21ur-7133 No description available WB:WBGene00168325 21ur-10247 No description available WB:WBGene00168326 21ur-15052 No description available WB:WBGene00168327 21ur-12993 No description available WB:WBGene00168328 21ur-6925 No description available WB:WBGene00168329 21ur-13338 No description available WB:WBGene00168330 21ur-12426 No description available WB:WBGene00168331 21ur-12057 No description available WB:WBGene00168332 21ur-6471 No description available WB:WBGene00168333 21ur-9449 No description available WB:WBGene00168334 21ur-14200 No description available WB:WBGene00168335 21ur-6229 No description available WB:WBGene00168336 21ur-8565 Is affected by daf-2 based on microarray studies. WB:WBGene00168337 21ur-7275 No description available WB:WBGene00168338 21ur-11232 No description available WB:WBGene00168339 21ur-10240 No description available WB:WBGene00168340 21ur-12802 No description available WB:WBGene00168341 21ur-10058 No description available WB:WBGene00168342 21ur-15325 No description available WB:WBGene00168343 21ur-9520 No description available WB:WBGene00168344 21ur-14909 No description available WB:WBGene00168345 21ur-9332 No description available WB:WBGene00168346 21ur-12249 No description available WB:WBGene00168347 21ur-13108 No description available WB:WBGene00168348 21ur-12782 No description available WB:WBGene00168349 21ur-10599 No description available WB:WBGene00168350 21ur-7812 No description available WB:WBGene00168351 21ur-9275 No description available WB:WBGene00168352 21ur-14292 No description available WB:WBGene00168353 21ur-13813 No description available WB:WBGene00168354 21ur-11659 No description available WB:WBGene00168355 21ur-13386 No description available WB:WBGene00168356 21ur-7256 No description available WB:WBGene00168357 21ur-7632 No description available WB:WBGene00168358 21ur-12453 No description available WB:WBGene00168359 21ur-9202 No description available WB:WBGene00168360 21ur-15314 No description available WB:WBGene00168361 21ur-5531 No description available WB:WBGene00168362 21ur-6525 No description available WB:WBGene00168363 21ur-8395 No description available WB:WBGene00168364 21ur-11571 No description available WB:WBGene00168365 21ur-12021 No description available WB:WBGene00168366 21ur-7007 No description available WB:WBGene00168367 21ur-10051 No description available WB:WBGene00168368 21ur-7523 No description available WB:WBGene00168369 21ur-15506 No description available WB:WBGene00168370 21ur-8707 No description available WB:WBGene00168371 21ur-10425 No description available WB:WBGene00168372 21ur-11993 No description available WB:WBGene00168373 21ur-9026 No description available WB:WBGene00168374 21ur-11884 No description available WB:WBGene00168375 21ur-11860 No description available WB:WBGene00168376 21ur-6851 No description available WB:WBGene00168377 21ur-13241 No description available WB:WBGene00168378 21ur-11721 No description available WB:WBGene00168379 21ur-9348 No description available WB:WBGene00168380 21ur-6774 No description available WB:WBGene00168381 21ur-7135 No description available WB:WBGene00168382 21ur-15081 No description available WB:WBGene00168383 21ur-5715 No description available WB:WBGene00168384 21ur-8476 No description available WB:WBGene00168385 21ur-8886 No description available WB:WBGene00168386 21ur-6868 No description available WB:WBGene00168387 21ur-14491 No description available WB:WBGene00168388 21ur-8263 No description available WB:WBGene00168389 21ur-14126 No description available WB:WBGene00168390 21ur-5557 No description available WB:WBGene00168391 21ur-8917 No description available WB:WBGene00168392 21ur-7080 Enriched in neurons based on RNA-seq studies. WB:WBGene00168393 21ur-11888 No description available WB:WBGene00168394 21ur-8413 No description available WB:WBGene00168395 21ur-13246 No description available WB:WBGene00168396 21ur-8456 No description available WB:WBGene00168397 21ur-14348 No description available WB:WBGene00168398 21ur-12185 No description available WB:WBGene00168399 21ur-15588 Is affected by spc-1 and unc-70 based on RNA-seq studies. WB:WBGene00168400 21ur-8088 No description available WB:WBGene00168401 21ur-10300 Enriched in neurons based on RNA-seq studies. WB:WBGene00168402 21ur-9837 No description available WB:WBGene00168403 21ur-15360 No description available WB:WBGene00168404 21ur-7041 No description available WB:WBGene00168405 21ur-15651 No description available WB:WBGene00168406 21ur-5690 No description available WB:WBGene00168407 21ur-15448 No description available WB:WBGene00168408 21ur-15291 No description available WB:WBGene00168409 21ur-8530 No description available WB:WBGene00168410 21ur-8996 No description available WB:WBGene00168411 21ur-14134 No description available WB:WBGene00168412 21ur-8182 No description available WB:WBGene00168413 21ur-13075 No description available WB:WBGene00168414 21ur-13165 No description available WB:WBGene00168415 21ur-10963 No description available WB:WBGene00168416 21ur-9440 Enriched in neurons based on RNA-seq studies. WB:WBGene00168417 21ur-14411 No description available WB:WBGene00168418 21ur-10084 No description available WB:WBGene00168419 21ur-11601 No description available WB:WBGene00168420 21ur-8861 No description available WB:WBGene00168421 21ur-13523 No description available WB:WBGene00168422 21ur-11130 No description available WB:WBGene00168423 21ur-8527 No description available WB:WBGene00168424 21ur-14592 No description available WB:WBGene00168425 21ur-13181 No description available WB:WBGene00168426 21ur-9266 No description available WB:WBGene00168427 21ur-11965 No description available WB:WBGene00168428 21ur-12696 No description available WB:WBGene00168429 21ur-6094 No description available WB:WBGene00168430 21ur-14144 No description available WB:WBGene00168431 21ur-6743 No description available WB:WBGene00168432 21ur-10568 No description available WB:WBGene00168433 21ur-14814 No description available WB:WBGene00168434 21ur-5723 No description available WB:WBGene00168435 21ur-7861 No description available WB:WBGene00168436 21ur-5710 No description available WB:WBGene00168437 21ur-10491 No description available WB:WBGene00168438 21ur-15565 No description available WB:WBGene00168439 21ur-13058 No description available WB:WBGene00168440 21ur-7118 No description available WB:WBGene00168441 21ur-9324 Enriched in neurons based on RNA-seq studies. WB:WBGene00168442 21ur-14294 No description available WB:WBGene00168443 21ur-15018 No description available WB:WBGene00168444 21ur-14768 Is affected by hsf-1 and cpl-1 based on RNA-seq studies. WB:WBGene00168445 21ur-7946 No description available WB:WBGene00168446 21ur-15335 No description available WB:WBGene00168447 21ur-10503 No description available WB:WBGene00168448 21ur-9247 No description available WB:WBGene00168449 21ur-15517 No description available WB:WBGene00168450 21ur-11638 No description available WB:WBGene00168451 21ur-11616 No description available WB:WBGene00168452 21ur-11840 No description available WB:WBGene00168453 21ur-13763 No description available WB:WBGene00168454 21ur-10149 No description available WB:WBGene00168455 21ur-13396 No description available WB:WBGene00168456 21ur-12527 No description available WB:WBGene00168457 21ur-11631 No description available WB:WBGene00168458 21ur-11979 No description available WB:WBGene00168459 21ur-9056 No description available WB:WBGene00168460 21ur-14552 No description available WB:WBGene00168461 21ur-15307 No description available WB:WBGene00168462 21ur-10282 No description available WB:WBGene00168463 21ur-7660 Enriched in neurons based on RNA-seq studies. WB:WBGene00168464 21ur-10606 No description available WB:WBGene00168465 21ur-5799 No description available WB:WBGene00168466 21ur-6163 No description available WB:WBGene00168467 21ur-9997 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00168468 21ur-13647 No description available WB:WBGene00168469 21ur-7793 No description available WB:WBGene00168470 21ur-12972 No description available WB:WBGene00168472 21ur-14540 No description available WB:WBGene00168473 21ur-11650 Is affected by hmg-4 based on RNA-seq studies. WB:WBGene00168474 21ur-10816 No description available WB:WBGene00168475 21ur-9551 No description available WB:WBGene00168476 21ur-15658 No description available WB:WBGene00168477 21ur-10436 No description available WB:WBGene00168478 21ur-14334 No description available WB:WBGene00168479 21ur-13776 No description available WB:WBGene00168480 21ur-7576 No description available WB:WBGene00168481 21ur-9289 No description available WB:WBGene00168482 21ur-6412 No description available WB:WBGene00168483 21ur-10929 No description available WB:WBGene00168484 21ur-14195 No description available WB:WBGene00168485 21ur-11263 No description available WB:WBGene00168486 21ur-7641 No description available WB:WBGene00168487 21ur-7144 No description available WB:WBGene00168488 21ur-15099 No description available WB:WBGene00168489 21ur-9541 No description available WB:WBGene00168490 21ur-7657 No description available WB:WBGene00168491 21ur-9787 No description available WB:WBGene00168492 21ur-6633 No description available WB:WBGene00168493 21ur-7426 No description available WB:WBGene00168494 21ur-10073 No description available WB:WBGene00168495 21ur-12482 No description available WB:WBGene00168496 21ur-6880 No description available WB:WBGene00168497 21ur-12219 No description available WB:WBGene00168498 21ur-11744 Is affected by ins-11 based on RNA-seq studies. WB:WBGene00168499 21ur-15547 No description available WB:WBGene00168500 21ur-9636 No description available WB:WBGene00168501 21ur-12032 No description available WB:WBGene00168502 21ur-9962 Enriched in neurons based on RNA-seq studies. WB:WBGene00168503 21ur-11782 No description available WB:WBGene00168504 21ur-9716 Enriched in neurons based on RNA-seq studies. WB:WBGene00168505 21ur-12279 No description available WB:WBGene00168506 21ur-12028 No description available WB:WBGene00168507 21ur-8221 No description available WB:WBGene00168508 21ur-13912 No description available WB:WBGene00168509 21ur-7920 No description available WB:WBGene00168510 21ur-11623 No description available WB:WBGene00168511 21ur-8493 No description available WB:WBGene00168512 21ur-7588 No description available WB:WBGene00168513 21ur-7770 No description available WB:WBGene00168514 21ur-7391 No description available WB:WBGene00168515 21ur-7017 No description available WB:WBGene00168516 21ur-10613 No description available WB:WBGene00168517 21ur-7901 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00168518 21ur-5529 No description available WB:WBGene00168519 21ur-13262 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00168520 21ur-9011 No description available WB:WBGene00168521 21ur-11220 No description available WB:WBGene00168522 21ur-10746 No description available WB:WBGene00168523 21ur-8036 No description available WB:WBGene00168524 21ur-11513 No description available WB:WBGene00168525 21ur-7826 No description available WB:WBGene00168526 21ur-8023 No description available WB:WBGene00168527 21ur-12034 No description available WB:WBGene00168528 21ur-14516 No description available WB:WBGene00168529 21ur-14525 Enriched in neurons based on RNA-seq studies. WB:WBGene00168530 21ur-7795 Enriched in neurons based on RNA-seq studies. WB:WBGene00168531 21ur-13619 No description available WB:WBGene00168532 21ur-13361 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00168533 21ur-15636 No description available WB:WBGene00168534 21ur-13458 No description available WB:WBGene00168535 21ur-9432 No description available WB:WBGene00168536 21ur-11800 No description available WB:WBGene00168537 21ur-13278 No description available WB:WBGene00168538 21ur-11656 No description available WB:WBGene00168539 21ur-12546 No description available WB:WBGene00168540 21ur-9465 Enriched in neurons based on RNA-seq studies. WB:WBGene00168541 21ur-9135 No description available WB:WBGene00168542 21ur-13020 No description available WB:WBGene00168543 21ur-10005 No description available WB:WBGene00168544 21ur-14952 No description available WB:WBGene00168545 21ur-13652 Enriched in neurons based on RNA-seq studies. WB:WBGene00168546 21ur-7614 No description available WB:WBGene00168547 21ur-11301 Enriched in neurons based on RNA-seq studies. WB:WBGene00168548 21ur-9924 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00168549 21ur-9391 No description available WB:WBGene00168550 21ur-8894 No description available WB:WBGene00168551 21ur-13856 No description available WB:WBGene00168552 21ur-10785 No description available WB:WBGene00168553 21ur-8371 No description available WB:WBGene00168554 21ur-11517 No description available WB:WBGene00168555 21ur-13033 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00168556 21ur-14529 No description available WB:WBGene00168557 21ur-11956 No description available WB:WBGene00168558 21ur-9532 No description available WB:WBGene00168559 21ur-13141 No description available WB:WBGene00168560 21ur-11891 No description available WB:WBGene00168561 21ur-10848 Enriched in neurons based on RNA-seq studies. WB:WBGene00168562 21ur-14900 No description available WB:WBGene00168563 21ur-13702 No description available WB:WBGene00168564 21ur-11259 No description available WB:WBGene00168565 21ur-14629 No description available WB:WBGene00168566 21ur-10856 No description available WB:WBGene00168567 21ur-14805 No description available WB:WBGene00168568 21ur-12926 No description available WB:WBGene00168569 21ur-12832 No description available WB:WBGene00168570 21ur-9708 No description available WB:WBGene00168571 21ur-8816 No description available WB:WBGene00168572 21ur-10617 No description available WB:WBGene00168573 21ur-15462 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00168574 21ur-6021 No description available WB:WBGene00168575 21ur-5683 No description available WB:WBGene00168576 21ur-12610 No description available WB:WBGene00168577 21ur-15195 No description available WB:WBGene00168578 21ur-8338 No description available WB:WBGene00168579 21ur-14107 No description available WB:WBGene00168580 21ur-14726 Enriched in neurons based on RNA-seq studies. WB:WBGene00168581 21ur-8927 No description available WB:WBGene00168582 21ur-10260 No description available WB:WBGene00168583 21ur-11620 No description available WB:WBGene00168584 21ur-6288 No description available WB:WBGene00168585 21ur-12230 No description available WB:WBGene00168586 21ur-15439 No description available WB:WBGene00168587 21ur-10532 No description available WB:WBGene00168588 21ur-5657 Is affected by eat-2 based on microarray studies. WB:WBGene00168589 21ur-13782 Is affected by zip-3 and smn-1 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00168590 21ur-13964 No description available WB:WBGene00168591 21ur-9811 No description available WB:WBGene00168592 21ur-7951 No description available WB:WBGene00168593 21ur-7323 No description available WB:WBGene00168594 21ur-10279 No description available WB:WBGene00168595 21ur-7129 No description available WB:WBGene00168596 21ur-6713 No description available WB:WBGene00168597 21ur-6355 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00168598 21ur-11312 No description available WB:WBGene00168599 21ur-9000 No description available WB:WBGene00168600 21ur-9404 No description available WB:WBGene00168601 21ur-13896 No description available WB:WBGene00168602 21ur-8856 No description available WB:WBGene00168603 21ur-9043 No description available WB:WBGene00168604 21ur-5567 No description available WB:WBGene00168605 21ur-5893 No description available WB:WBGene00168606 21ur-8295 No description available WB:WBGene00168607 21ur-13260 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00168608 21ur-11698 No description available WB:WBGene00168609 21ur-7387 No description available WB:WBGene00168610 21ur-9097 No description available WB:WBGene00168611 21ur-10829 No description available WB:WBGene00168612 21ur-6183 No description available WB:WBGene00168613 21ur-8783 No description available WB:WBGene00168614 21ur-14130 No description available WB:WBGene00168615 21ur-7994 No description available WB:WBGene00168616 21ur-14324 No description available WB:WBGene00168617 21ur-9625 No description available WB:WBGene00168618 21ur-7895 Enriched in neurons based on RNA-seq studies. WB:WBGene00168619 21ur-7732 No description available WB:WBGene00168620 21ur-8077 No description available WB:WBGene00168621 21ur-8483 No description available WB:WBGene00168622 21ur-9485 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00168623 21ur-7628 No description available WB:WBGene00168624 21ur-7149 No description available WB:WBGene00168625 21ur-10985 No description available WB:WBGene00168626 21ur-13585 No description available WB:WBGene00168627 21ur-15030 Is affected by lem-2; emr-1; and cpl-1 based on RNA-seq studies. WB:WBGene00168628 21ur-5753 No description available WB:WBGene00168629 21ur-10652 No description available WB:WBGene00168630 21ur-5783 No description available WB:WBGene00168631 21ur-14695 No description available WB:WBGene00168632 21ur-8843 No description available WB:WBGene00168633 21ur-12356 No description available WB:WBGene00168634 21ur-11041 No description available WB:WBGene00168635 21ur-7073 No description available WB:WBGene00168636 21ur-9037 No description available WB:WBGene00168637 21ur-9294 Enriched in neurons based on RNA-seq studies. WB:WBGene00168638 21ur-14047 No description available WB:WBGene00168639 21ur-7727 No description available WB:WBGene00168640 21ur-8920 No description available WB:WBGene00168641 21ur-5820 No description available WB:WBGene00168642 21ur-5938 Enriched in neurons based on RNA-seq studies. WB:WBGene00168643 21ur-8465 No description available WB:WBGene00168644 21ur-7873 No description available WB:WBGene00168645 21ur-6764 No description available WB:WBGene00168646 21ur-8343 No description available WB:WBGene00168647 21ur-7705 Enriched in neurons based on RNA-seq studies. WB:WBGene00168648 21ur-8877 No description available WB:WBGene00168649 21ur-8248 No description available WB:WBGene00168650 21ur-12216 No description available WB:WBGene00168651 21ur-12384 No description available WB:WBGene00168652 21ur-7581 No description available WB:WBGene00168653 21ur-11209 No description available WB:WBGene00168654 21ur-12145 No description available WB:WBGene00168655 21ur-11455 No description available WB:WBGene00168656 21ur-14098 No description available WB:WBGene00168657 21ur-13637 No description available WB:WBGene00168658 21ur-11280 Enriched in neurons based on RNA-seq studies. WB:WBGene00168659 21ur-15387 Is affected by several genes including lem-2; cpl-1; and emr-1 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies. WB:WBGene00168660 21ur-7430 No description available WB:WBGene00168661 21ur-8691 No description available WB:WBGene00168662 21ur-10901 No description available WB:WBGene00168663 21ur-11229 No description available WB:WBGene00168664 21ur-13569 No description available WB:WBGene00168665 21ur-9659 No description available WB:WBGene00168666 21ur-5896 Enriched in AFD based on RNA-seq studies. Is affected by set-2 and hlh-26 based on RNA-seq studies. WB:WBGene00168667 21ur-14229 No description available WB:WBGene00168668 21ur-12273 No description available WB:WBGene00168669 21ur-11095 No description available WB:WBGene00168670 21ur-11252 No description available WB:WBGene00168671 21ur-9152 No description available WB:WBGene00168672 21ur-6143 No description available WB:WBGene00168673 21ur-6629 Enriched in neurons based on RNA-seq studies. WB:WBGene00168674 21ur-12630 No description available WB:WBGene00168675 21ur-9598 No description available WB:WBGene00168676 21ur-10270 No description available WB:WBGene00168677 21ur-11200 No description available WB:WBGene00168678 21ur-9291 No description available WB:WBGene00168679 21ur-9415 No description available WB:WBGene00168680 21ur-11335 No description available WB:WBGene00168681 21ur-13176 No description available WB:WBGene00168682 21ur-6115 No description available WB:WBGene00168683 21ur-13934 No description available WB:WBGene00168684 21ur-11502 No description available WB:WBGene00168685 21ur-8821 No description available WB:WBGene00168686 21ur-14040 No description available WB:WBGene00168687 21ur-6654 No description available WB:WBGene00168688 21ur-8800 No description available WB:WBGene00168689 21ur-15205 No description available WB:WBGene00168690 21ur-10646 Enriched in neurons based on RNA-seq studies. WB:WBGene00168691 21ur-15132 No description available WB:WBGene00168692 21ur-14871 No description available WB:WBGene00168693 21ur-13509 No description available WB:WBGene00168694 21ur-14824 No description available WB:WBGene00168695 21ur-10369 No description available WB:WBGene00168696 21ur-5730 No description available WB:WBGene00168697 21ur-7303 No description available WB:WBGene00168698 21ur-5506 No description available WB:WBGene00168699 21ur-8943 No description available WB:WBGene00168700 21ur-12762 Enriched in neurons based on RNA-seq studies. WB:WBGene00168701 21ur-10375 No description available WB:WBGene00168702 21ur-14113 No description available WB:WBGene00168703 21ur-11403 No description available WB:WBGene00168704 21ur-14011 No description available WB:WBGene00168705 21ur-5905 No description available WB:WBGene00168706 21ur-6390 Enriched in neurons based on RNA-seq studies. WB:WBGene00168707 21ur-15380 No description available WB:WBGene00168708 21ur-12705 No description available WB:WBGene00168709 21ur-13941 No description available WB:WBGene00168710 21ur-14313 No description available WB:WBGene00168711 21ur-14224 No description available WB:WBGene00168712 21ur-7331 No description available WB:WBGene00168713 21ur-10328 No description available WB:WBGene00168714 21ur-9799 No description available WB:WBGene00168715 21ur-12633 No description available WB:WBGene00168716 21ur-7552 No description available WB:WBGene00168717 21ur-13125 No description available WB:WBGene00168718 21ur-6375 No description available WB:WBGene00168719 21ur-9794 No description available WB:WBGene00168720 21ur-5930 No description available WB:WBGene00168721 21ur-8331 Enriched in neurons based on RNA-seq studies. WB:WBGene00168722 21ur-5919 No description available WB:WBGene00168723 21ur-11343 No description available WB:WBGene00168724 21ur-8193 No description available WB:WBGene00168725 21ur-8607 No description available WB:WBGene00168726 21ur-11025 No description available WB:WBGene00168727 21ur-15512 No description available WB:WBGene00168728 21ur-6013 No description available WB:WBGene00168729 21ur-6906 No description available WB:WBGene00168730 21ur-7338 No description available WB:WBGene00168731 21ur-15159 No description available WB:WBGene00168732 21ur-14151 No description available WB:WBGene00168733 21ur-5584 No description available WB:WBGene00168734 21ur-14088 No description available WB:WBGene00168735 21ur-13881 No description available WB:WBGene00168736 21ur-11551 No description available WB:WBGene00168737 21ur-11546 No description available WB:WBGene00168738 21ur-9112 No description available WB:WBGene00168739 21ur-9494 No description available WB:WBGene00168740 21ur-10269 No description available WB:WBGene00168741 21ur-15049 No description available WB:WBGene00168742 21ur-14890 No description available WB:WBGene00168743 21ur-13377 Is affected by cadmium based on RNA-seq studies. WB:WBGene00168744 21ur-10184 No description available WB:WBGene00168745 21ur-14181 No description available WB:WBGene00168746 21ur-13158 No description available WB:WBGene00168747 21ur-13597 No description available WB:WBGene00168748 21ur-6297 No description available WB:WBGene00168749 21ur-15369 No description available WB:WBGene00168750 21ur-12825 No description available WB:WBGene00168751 21ur-12604 No description available WB:WBGene00168752 21ur-12171 No description available WB:WBGene00168753 21ur-7161 No description available WB:WBGene00168754 21ur-9765 No description available WB:WBGene00168755 21ur-11491 No description available WB:WBGene00168756 21ur-7595 No description available WB:WBGene00168757 21ur-7032 No description available WB:WBGene00168758 21ur-11446 No description available WB:WBGene00168759 21ur-7314 No description available WB:WBGene00168760 21ur-12960 No description available WB:WBGene00168761 21ur-15127 No description available WB:WBGene00168762 21ur-6507 No description available WB:WBGene00168763 21ur-13603 No description available WB:WBGene00168764 21ur-9231 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00168765 21ur-15612 No description available WB:WBGene00168766 21ur-14622 No description available WB:WBGene00168767 21ur-13622 No description available WB:WBGene00168768 21ur-8143 No description available WB:WBGene00168769 21ur-6436 No description available WB:WBGene00168770 21ur-11791 No description available WB:WBGene00168771 21ur-8760 No description available WB:WBGene00168772 21ur-15486 No description available WB:WBGene00168773 21ur-12672 No description available WB:WBGene00168774 21ur-10834 No description available WB:WBGene00168775 21ur-10472 No description available WB:WBGene00168776 21ur-6073 No description available WB:WBGene00168777 21ur-14139 No description available WB:WBGene00168778 21ur-14581 No description available WB:WBGene00168779 21ur-6517 No description available WB:WBGene00168780 21ur-9468 No description available WB:WBGene00168781 21ur-14852 No description available WB:WBGene00168782 21ur-10395 Enriched in neurons based on RNA-seq studies. WB:WBGene00168783 21ur-7978 No description available WB:WBGene00168784 21ur-15686 No description available WB:WBGene00168785 21ur-15355 No description available WB:WBGene00168786 21ur-7245 No description available WB:WBGene00168787 21ur-9419 No description available WB:WBGene00168788 21ur-15153 No description available WB:WBGene00168789 21ur-5866 No description available WB:WBGene00168790 21ur-10105 No description available WB:WBGene00168791 21ur-11671 No description available WB:WBGene00168792 21ur-8756 No description available WB:WBGene00168793 21ur-14244 No description available WB:WBGene00168794 21ur-12861 No description available WB:WBGene00168795 21ur-5712 No description available WB:WBGene00168796 21ur-8472 No description available WB:WBGene00168797 21ur-12881 No description available WB:WBGene00168798 21ur-15067 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00168799 21ur-7154 No description available WB:WBGene00168800 21ur-11058 No description available WB:WBGene00168801 21ur-6955 No description available WB:WBGene00168802 21ur-7468 No description available WB:WBGene00168803 21ur-5800 No description available WB:WBGene00168804 21ur-8132 No description available WB:WBGene00168805 21ur-13040 Enriched in neurons based on RNA-seq studies. WB:WBGene00168806 21ur-7306 No description available WB:WBGene00168807 21ur-11461 No description available WB:WBGene00168808 21ur-9682 No description available WB:WBGene00168809 21ur-5666 No description available WB:WBGene00168810 21ur-9259 No description available WB:WBGene00168811 21ur-15075 No description available WB:WBGene00168812 21ur-12684 No description available WB:WBGene00168813 21ur-7689 No description available WB:WBGene00168814 21ur-14646 No description available WB:WBGene00168815 21ur-6101 Enriched in neurons based on RNA-seq studies. WB:WBGene00168816 21ur-8887 No description available WB:WBGene00168817 21ur-10539 No description available WB:WBGene00168818 21ur-11089 No description available WB:WBGene00168819 21ur-14941 No description available WB:WBGene00168820 21ur-10636 Enriched in neurons based on RNA-seq studies. WB:WBGene00168821 21ur-14385 No description available WB:WBGene00168822 21ur-9491 No description available WB:WBGene00168823 21ur-8307 No description available WB:WBGene00168824 21ur-12544 No description available WB:WBGene00168825 21ur-6725 No description available WB:WBGene00168826 21ur-14573 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00168827 21ur-14147 No description available WB:WBGene00168828 21ur-12326 No description available WB:WBGene00168829 21ur-8770 No description available WB:WBGene00168830 21ur-6249 No description available WB:WBGene00168831 21ur-5686 No description available WB:WBGene00168832 21ur-6941 No description available WB:WBGene00168833 21ur-9172 No description available WB:WBGene00168834 21ur-8341 No description available WB:WBGene00168835 21ur-13954 No description available WB:WBGene00168836 21ur-13916 No description available WB:WBGene00168837 21ur-11654 No description available WB:WBGene00168838 21ur-7147 No description available WB:WBGene00168839 21ur-12498 No description available WB:WBGene00168840 21ur-9935 No description available WB:WBGene00168841 21ur-8392 No description available WB:WBGene00168842 21ur-13133 No description available WB:WBGene00168843 21ur-6006 Enriched in neurons based on RNA-seq studies. WB:WBGene00168844 21ur-8375 No description available WB:WBGene00168845 21ur-15572 No description available WB:WBGene00168846 21ur-15007 No description available WB:WBGene00168847 21ur-7903 No description available WB:WBGene00168848 21ur-10664 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00168849 21ur-8086 No description available WB:WBGene00168850 21ur-12436 No description available WB:WBGene00168851 21ur-10137 No description available WB:WBGene00168852 21ur-7328 No description available WB:WBGene00168853 21ur-14874 No description available WB:WBGene00168854 21ur-8632 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00168855 21ur-9829 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00168856 21ur-14798 No description available WB:WBGene00168857 21ur-13537 No description available WB:WBGene00168858 21ur-11990 No description available WB:WBGene00168859 21ur-14350 No description available WB:WBGene00168860 21ur-10031 No description available WB:WBGene00168861 21ur-9671 No description available WB:WBGene00168862 21ur-11010 No description available WB:WBGene00168863 21ur-9314 No description available WB:WBGene00168864 21ur-12807 No description available WB:WBGene00168865 21ur-14166 No description available WB:WBGene00168866 21ur-7058 No description available WB:WBGene00168867 21ur-8611 No description available WB:WBGene00168868 21ur-13285 No description available WB:WBGene00168869 21ur-10896 No description available WB:WBGene00168870 21ur-8166 No description available WB:WBGene00168871 21ur-9975 No description available WB:WBGene00168872 21ur-10887 No description available WB:WBGene00168873 21ur-7227 No description available WB:WBGene00168874 21ur-6061 No description available WB:WBGene00168875 21ur-7396 No description available WB:WBGene00168876 21ur-10457 No description available WB:WBGene00168877 21ur-10301 No description available WB:WBGene00168878 21ur-12462 No description available WB:WBGene00168879 21ur-8480 No description available WB:WBGene00168880 21ur-11135 No description available WB:WBGene00168881 21ur-11997 No description available WB:WBGene00168882 21ur-8819 No description available WB:WBGene00168883 21ur-5928 No description available WB:WBGene00168884 21ur-11141 Is affected by olrn-1 based on RNA-seq studies. WB:WBGene00168885 21ur-10573 No description available WB:WBGene00168886 21ur-9980 No description available WB:WBGene00168887 21ur-12000 No description available WB:WBGene00168888 21ur-10226 No description available WB:WBGene00168889 21ur-10422 No description available WB:WBGene00168890 21ur-13116 No description available WB:WBGene00168891 21ur-14812 No description available WB:WBGene00168892 21ur-12599 No description available WB:WBGene00168893 21ur-8003 No description available WB:WBGene00168894 21ur-11414 No description available WB:WBGene00168895 21ur-7791 No description available WB:WBGene00168896 21ur-8812 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00168897 21ur-12988 No description available WB:WBGene00168898 21ur-12916 No description available WB:WBGene00168899 21ur-14685 No description available WB:WBGene00168900 21ur-9882 No description available WB:WBGene00168901 21ur-6556 No description available WB:WBGene00168902 21ur-15375 Enriched in neurons based on RNA-seq studies. WB:WBGene00168903 21ur-9988 No description available WB:WBGene00168904 21ur-6150 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00168905 21ur-5573 Enriched in neurons based on RNA-seq studies. WB:WBGene00168906 21ur-11362 No description available WB:WBGene00168907 21ur-6970 No description available WB:WBGene00168908 21ur-7756 No description available WB:WBGene00168909 21ur-13722 No description available WB:WBGene00168910 21ur-5887 No description available WB:WBGene00168911 21ur-11641 No description available WB:WBGene00168912 21ur-8326 No description available WB:WBGene00168913 21ur-10177 No description available WB:WBGene00168914 21ur-10781 No description available WB:WBGene00168915 21ur-12346 Is affected by Tamoxifen based on RNA-seq studies. WB:WBGene00168916 21ur-15286 No description available WB:WBGene00168917 21ur-6066 No description available WB:WBGene00168918 21ur-9886 No description available WB:WBGene00168919 21ur-8096 No description available WB:WBGene00168920 21ur-9767 No description available WB:WBGene00168921 21ur-5519 No description available WB:WBGene00168922 21ur-8545 No description available WB:WBGene00168923 21ur-6699 No description available WB:WBGene00168924 21ur-11742 No description available WB:WBGene00168925 21ur-10934 No description available WB:WBGene00168926 21ur-10884 No description available WB:WBGene00168927 21ur-10026 No description available WB:WBGene00168928 21ur-15183 No description available WB:WBGene00168929 21ur-11868 No description available WB:WBGene00168930 21ur-10937 No description available WB:WBGene00168931 21ur-6267 No description available WB:WBGene00168932 21ur-9217 No description available WB:WBGene00168933 21ur-10700 No description available WB:WBGene00168934 21ur-8233 Enriched in neurons based on RNA-seq studies. WB:WBGene00168935 21ur-8739 No description available WB:WBGene00168936 21ur-6148 No description available WB:WBGene00168937 21ur-12911 No description available WB:WBGene00168938 21ur-8973 No description available WB:WBGene00168939 21ur-15340 No description available WB:WBGene00168940 21ur-11935 No description available WB:WBGene00168941 21ur-15028 No description available WB:WBGene00168942 21ur-9365 No description available WB:WBGene00168943 21ur-14347 No description available WB:WBGene00168944 21ur-10608 No description available WB:WBGene00168945 21ur-9181 No description available WB:WBGene00168946 21ur-7195 No description available WB:WBGene00168947 21ur-15549 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00168948 21ur-11816 No description available WB:WBGene00168949 21ur-13798 No description available WB:WBGene00168950 21ur-12070 No description available WB:WBGene00168951 21ur-11179 No description available WB:WBGene00168952 21ur-11082 No description available WB:WBGene00168953 21ur-10582 No description available WB:WBGene00168954 21ur-9466 No description available WB:WBGene00168955 21ur-15607 No description available WB:WBGene00168956 21ur-12669 No description available WB:WBGene00168957 21ur-6276 No description available WB:WBGene00168958 21ur-11113 No description available WB:WBGene00168959 21ur-5775 No description available WB:WBGene00168960 21ur-13557 No description available WB:WBGene00168961 21ur-6604 Enriched in neurons based on RNA-seq studies. WB:WBGene00168962 21ur-12990 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00168963 21ur-8618 No description available WB:WBGene00168964 21ur-6433 No description available WB:WBGene00168965 21ur-12511 No description available WB:WBGene00168966 21ur-13414 No description available WB:WBGene00168967 21ur-11905 No description available WB:WBGene00168968 21ur-15602 No description available WB:WBGene00168969 21ur-9861 Is affected by emr-1; lem-2; and rnp-6 based on RNA-seq studies. WB:WBGene00168970 21ur-13854 Is affected by spr-5 based on RNA-seq studies. WB:WBGene00168971 21ur-12040 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 and met-2 based on RNA-seq studies. WB:WBGene00168972 21ur-9252 No description available WB:WBGene00168973 21ur-12173 No description available WB:WBGene00168974 21ur-7496 No description available WB:WBGene00168975 21ur-11190 No description available WB:WBGene00168976 21ur-7831 No description available WB:WBGene00168977 21ur-12388 No description available WB:WBGene00168978 21ur-10235 No description available WB:WBGene00168979 21ur-6695 No description available WB:WBGene00168980 21ur-13356 Enriched in neurons based on RNA-seq studies. WB:WBGene00168981 21ur-6240 No description available WB:WBGene00168982 21ur-9750 No description available WB:WBGene00168983 21ur-5600 No description available WB:WBGene00168984 21ur-14631 No description available WB:WBGene00168985 21ur-9076 No description available WB:WBGene00168986 21ur-15600 No description available WB:WBGene00168987 21ur-10019 No description available WB:WBGene00168988 21ur-13786 No description available WB:WBGene00168989 21ur-11706 Is affected by several genes including mdt-15; met-2; and spr-5 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00168990 21ur-13195 Enriched in neurons based on RNA-seq studies. WB:WBGene00168991 21ur-14356 No description available WB:WBGene00168992 21ur-7345 No description available WB:WBGene00168993 21ur-5744 No description available WB:WBGene00168994 21ur-15452 No description available WB:WBGene00168995 21ur-8254 No description available WB:WBGene00168996 21ur-9776 No description available WB:WBGene00168997 21ur-11385 No description available WB:WBGene00168998 21ur-5851 No description available WB:WBGene00168999 21ur-10758 No description available WB:WBGene00169000 21ur-12310 No description available WB:WBGene00169001 21ur-12079 No description available WB:WBGene00169002 21ur-11332 No description available WB:WBGene00169003 21ur-10587 No description available WB:WBGene00169004 21ur-7481 No description available WB:WBGene00169005 21ur-7772 No description available WB:WBGene00169006 21ur-6372 No description available WB:WBGene00169007 21ur-11967 No description available WB:WBGene00169008 21ur-15610 No description available WB:WBGene00169009 21ur-7654 No description available WB:WBGene00169010 21ur-8524 Enriched in neurons based on RNA-seq studies. WB:WBGene00169011 21ur-12829 No description available WB:WBGene00169012 21ur-7859 No description available WB:WBGene00169013 21ur-12050 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00169014 21ur-7334 No description available WB:WBGene00169015 21ur-13791 No description available WB:WBGene00169016 21ur-7507 No description available WB:WBGene00169017 21ur-8336 No description available WB:WBGene00169018 21ur-10258 No description available WB:WBGene00169019 21ur-9643 No description available WB:WBGene00169020 21ur-10299 No description available WB:WBGene00169021 21ur-14897 No description available WB:WBGene00169022 21ur-9128 No description available WB:WBGene00169023 21ur-7107 Enriched in neurons based on RNA-seq studies. WB:WBGene00169024 21ur-5599 No description available WB:WBGene00169025 21ur-8279 No description available WB:WBGene00169026 21ur-12923 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00169027 21ur-7454 No description available WB:WBGene00169028 21ur-15422 No description available WB:WBGene00169029 21ur-14269 Is affected by damt-1 and cox-5B based on RNA-seq studies. Is affected by antimycin and paraquat based on RNA-seq studies. WB:WBGene00169030 21ur-11225 No description available WB:WBGene00169031 21ur-6465 No description available WB:WBGene00169032 21ur-14935 No description available WB:WBGene00169033 21ur-7515 No description available WB:WBGene00169034 21ur-9743 No description available WB:WBGene00169035 21ur-7635 No description available WB:WBGene00169036 21ur-13607 No description available WB:WBGene00169037 21ur-12122 No description available WB:WBGene00169038 21ur-14235 No description available WB:WBGene00169039 21ur-13975 No description available WB:WBGene00169040 21ur-9458 No description available WB:WBGene00169041 21ur-9913 No description available WB:WBGene00169042 21ur-14205 No description available WB:WBGene00169043 21ur-6318 No description available WB:WBGene00169044 21ur-10319 No description available WB:WBGene00169045 21ur-12474 No description available WB:WBGene00169046 21ur-14795 No description available WB:WBGene00169047 21ur-7955 No description available WB:WBGene00169048 21ur-10465 No description available WB:WBGene00169049 21ur-9584 No description available WB:WBGene00169050 21ur-11566 No description available WB:WBGene00169051 21ur-6481 Enriched in neurons based on RNA-seq studies. WB:WBGene00169052 21ur-9471 No description available WB:WBGene00169053 21ur-14913 No description available WB:WBGene00169054 21ur-13600 No description available WB:WBGene00169055 21ur-9555 Is affected by meg-3 and meg-4 based on RNA-seq studies. WB:WBGene00169056 21ur-10057 No description available WB:WBGene00169057 21ur-6010 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00169058 21ur-6993 No description available WB:WBGene00169059 21ur-6561 No description available WB:WBGene00169060 21ur-7517 No description available WB:WBGene00169061 21ur-7533 No description available WB:WBGene00169062 21ur-13926 No description available WB:WBGene00169063 21ur-7451 No description available WB:WBGene00169064 21ur-13515 No description available WB:WBGene00169065 21ur-6595 No description available WB:WBGene00169066 21ur-8203 No description available WB:WBGene00169067 21ur-10973 No description available WB:WBGene00169068 21ur-6979 No description available WB:WBGene00169069 21ur-10739 No description available WB:WBGene00169070 21ur-6300 Is affected by set-2 based on RNA-seq studies. WB:WBGene00169071 21ur-11933 No description available WB:WBGene00169072 21ur-15576 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169073 21ur-9689 No description available WB:WBGene00169074 21ur-8052 No description available WB:WBGene00169075 21ur-14560 No description available WB:WBGene00169076 21ur-8485 No description available WB:WBGene00169077 21ur-6199 No description available WB:WBGene00169078 21ur-8270 No description available WB:WBGene00169079 21ur-12757 No description available WB:WBGene00169080 21ur-8720 No description available WB:WBGene00169081 21ur-14931 No description available WB:WBGene00169082 21ur-7560 No description available WB:WBGene00169083 21ur-9373 No description available WB:WBGene00169084 21ur-6673 No description available WB:WBGene00169085 21ur-13019 No description available WB:WBGene00169086 21ur-14882 No description available WB:WBGene00169087 21ur-10040 No description available WB:WBGene00169088 21ur-8993 No description available WB:WBGene00169089 21ur-12235 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00169090 21ur-12009 No description available WB:WBGene00169091 21ur-9955 No description available WB:WBGene00169092 21ur-11124 No description available WB:WBGene00169093 21ur-5534 No description available WB:WBGene00169094 21ur-8189 No description available WB:WBGene00169095 21ur-8839 No description available WB:WBGene00169096 21ur-10384 No description available WB:WBGene00169097 21ur-6814 No description available WB:WBGene00169098 21ur-14323 No description available WB:WBGene00169099 21ur-13006 No description available WB:WBGene00169100 21ur-6204 No description available WB:WBGene00169101 21ur-12306 No description available WB:WBGene00169102 21ur-9847 No description available WB:WBGene00169103 21ur-7102 No description available WB:WBGene00169104 21ur-13283 No description available WB:WBGene00169105 21ur-8196 Is affected by ints-5 based on RNA-seq studies. WB:WBGene00169106 21ur-7759 No description available WB:WBGene00169107 21ur-14085 No description available WB:WBGene00169108 21ur-12334 No description available WB:WBGene00169109 21ur-14757 No description available WB:WBGene00169110 21ur-14034 No description available WB:WBGene00169111 21ur-12566 No description available WB:WBGene00169112 21ur-7325 No description available WB:WBGene00169113 21ur-6826 No description available WB:WBGene00169114 21ur-8806 Enriched in neurons based on RNA-seq studies. WB:WBGene00169115 21ur-12063 No description available WB:WBGene00169116 21ur-12602 No description available WB:WBGene00169117 21ur-12350 No description available WB:WBGene00169118 21ur-14928 Enriched in neurons based on RNA-seq studies. WB:WBGene00169119 21ur-13018 No description available WB:WBGene00169120 21ur-7171 No description available WB:WBGene00169121 21ur-13029 No description available WB:WBGene00169122 21ur-10790 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00169123 21ur-10037 No description available WB:WBGene00169124 21ur-14391 No description available WB:WBGene00169125 21ur-14366 No description available WB:WBGene00169126 21ur-6385 No description available WB:WBGene00169127 21ur-15176 No description available WB:WBGene00169128 21ur-14397 No description available WB:WBGene00169129 21ur-14028 No description available WB:WBGene00169130 21ur-15142 No description available WB:WBGene00169131 21ur-9330 No description available WB:WBGene00169132 21ur-14316 No description available WB:WBGene00169133 21ur-6714 No description available WB:WBGene00169134 21ur-5493 Enriched in neurons based on RNA-seq studies. WB:WBGene00169135 21ur-10494 No description available WB:WBGene00169136 21ur-6793 No description available WB:WBGene00169137 21ur-12586 No description available WB:WBGene00169138 21ur-6818 No description available WB:WBGene00169139 21ur-14429 No description available WB:WBGene00169140 21ur-6313 No description available WB:WBGene00169141 21ur-12979 No description available WB:WBGene00169142 21ur-9064 No description available WB:WBGene00169143 21ur-5765 Enriched in neurons based on RNA-seq studies. WB:WBGene00169144 21ur-10732 No description available WB:WBGene00169145 21ur-7404 No description available WB:WBGene00169146 21ur-13157 No description available WB:WBGene00169147 21ur-8665 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169148 21ur-6708 No description available WB:WBGene00169149 21ur-7721 No description available WB:WBGene00169150 21ur-15615 No description available WB:WBGene00169151 21ur-12852 No description available WB:WBGene00169152 21ur-10978 No description available WB:WBGene00169153 21ur-9197 No description available WB:WBGene00169154 21ur-11342 No description available WB:WBGene00169155 21ur-14068 No description available WB:WBGene00169156 21ur-12268 No description available WB:WBGene00169157 21ur-10839 No description available WB:WBGene00169158 21ur-11077 No description available WB:WBGene00169159 21ur-8981 No description available WB:WBGene00169160 21ur-8847 No description available WB:WBGene00169161 21ur-6514 No description available WB:WBGene00169162 21ur-10726 No description available WB:WBGene00169163 21ur-15667 No description available WB:WBGene00169164 21ur-12256 No description available WB:WBGene00169165 21ur-11556 No description available WB:WBGene00169166 21ur-13566 No description available WB:WBGene00169167 21ur-13223 No description available WB:WBGene00169168 21ur-13056 No description available WB:WBGene00169169 21ur-12479 No description available WB:WBGene00169170 21ur-6504 No description available WB:WBGene00169171 21ur-7676 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00169172 21ur-8145 No description available WB:WBGene00169173 21ur-11684 No description available WB:WBGene00169174 21ur-7878 No description available WB:WBGene00169175 21ur-13919 No description available WB:WBGene00169176 21ur-12579 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00169177 21ur-9739 No description available WB:WBGene00169178 21ur-11847 No description available WB:WBGene00169179 21ur-12713 No description available WB:WBGene00169180 21ur-13736 No description available WB:WBGene00169181 21ur-7701 No description available WB:WBGene00169182 21ur-15232 No description available WB:WBGene00169183 21ur-6478 Is affected by set-2 based on RNA-seq studies. WB:WBGene00169184 21ur-11921 No description available WB:WBGene00169185 21ur-9101 No description available WB:WBGene00169186 21ur-13084 No description available WB:WBGene00169187 21ur-14117 No description available WB:WBGene00169188 21ur-8126 Is affected by nfki-1 and etr-1 based on RNA-seq studies. WB:WBGene00169189 21ur-9155 Enriched in neurons based on RNA-seq studies. WB:WBGene00169190 21ur-14607 No description available WB:WBGene00169191 21ur-14609 No description available WB:WBGene00169192 21ur-13775 No description available WB:WBGene00169193 21ur-7343 No description available WB:WBGene00169194 21ur-12221 No description available WB:WBGene00169195 21ur-10372 No description available WB:WBGene00169196 21ur-8832 No description available WB:WBGene00169197 21ur-10296 Is affected by several genes including lem-2; emr-1; and hda-2 based on RNA-seq studies. WB:WBGene00169198 21ur-11763 No description available WB:WBGene00169199 21ur-6365 No description available WB:WBGene00169200 21ur-12357 No description available WB:WBGene00169201 21ur-11852 No description available WB:WBGene00169202 21ur-8328 No description available WB:WBGene00169203 21ur-15629 No description available WB:WBGene00169204 21ur-10366 No description available WB:WBGene00169205 21ur-10312 No description available WB:WBGene00169206 21ur-9592 No description available WB:WBGene00169207 21ur-7881 No description available WB:WBGene00169208 21ur-11693 No description available WB:WBGene00169209 21ur-8648 No description available WB:WBGene00169210 21ur-15593 No description available WB:WBGene00169211 21ur-5605 No description available WB:WBGene00169212 21ur-12292 Enriched in neurons based on RNA-seq studies. WB:WBGene00169213 21ur-11928 No description available WB:WBGene00169214 21ur-12476 No description available WB:WBGene00169215 21ur-9165 No description available WB:WBGene00169216 21ur-5826 No description available WB:WBGene00169217 21ur-8500 No description available WB:WBGene00169218 21ur-8516 No description available WB:WBGene00169219 21ur-8441 No description available WB:WBGene00169220 21ur-9529 No description available WB:WBGene00169221 21ur-10873 No description available WB:WBGene00169222 21ur-15400 No description available WB:WBGene00169223 21ur-15021 No description available WB:WBGene00169224 21ur-15524 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00169225 21ur-14024 No description available WB:WBGene00169226 21ur-8684 No description available WB:WBGene00169227 21ur-15121 No description available WB:WBGene00169228 21ur-14968 No description available WB:WBGene00169229 21ur-12878 No description available WB:WBGene00169230 21ur-9058 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169231 21ur-15202 No description available WB:WBGene00169232 21ur-14710 No description available WB:WBGene00169233 21ur-12024 No description available WB:WBGene00169234 21ur-11587 No description available WB:WBGene00169235 21ur-7988 No description available WB:WBGene00169236 21ur-15398 No description available WB:WBGene00169237 21ur-11189 No description available WB:WBGene00169238 21ur-6757 No description available WB:WBGene00169239 21ur-14690 No description available WB:WBGene00169240 21ur-10063 No description available WB:WBGene00169242 21ur-11375 No description available WB:WBGene00169243 21ur-13329 No description available WB:WBGene00169244 21ur-11450 No description available WB:WBGene00169245 21ur-13800 No description available WB:WBGene00169246 21ur-6230 No description available WB:WBGene00169247 21ur-10196 No description available WB:WBGene00169248 21ur-9433 No description available WB:WBGene00169249 21ur-8936 No description available WB:WBGene00169250 21ur-13440 No description available WB:WBGene00169251 21ur-12983 No description available WB:WBGene00169252 21ur-10942 No description available WB:WBGene00169253 21ur-12106 No description available WB:WBGene00169254 21ur-12015 No description available WB:WBGene00169255 21ur-15158 No description available WB:WBGene00169256 21ur-7912 No description available WB:WBGene00169257 21ur-9148 No description available WB:WBGene00169258 21ur-12500 No description available WB:WBGene00169259 21ur-10313 No description available WB:WBGene00169260 21ur-10431 No description available WB:WBGene00169261 21ur-7381 No description available WB:WBGene00169262 21ur-8200 No description available WB:WBGene00169263 21ur-8429 No description available WB:WBGene00169264 21ur-13294 No description available WB:WBGene00169265 21ur-5675 No description available WB:WBGene00169266 21ur-9857 No description available WB:WBGene00169267 21ur-13036 No description available WB:WBGene00169268 21ur-6172 No description available WB:WBGene00169269 21ur-14723 No description available WB:WBGene00169270 21ur-11833 No description available WB:WBGene00169271 21ur-14709 No description available WB:WBGene00169272 21ur-13409 No description available WB:WBGene00169273 21ur-6904 No description available WB:WBGene00169274 21ur-9927 No description available WB:WBGene00169275 21ur-7669 No description available WB:WBGene00169276 21ur-8597 No description available WB:WBGene00169277 21ur-12613 No description available WB:WBGene00169278 21ur-9840 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00169279 21ur-11919 No description available WB:WBGene00169280 21ur-11219 No description available WB:WBGene00169281 21ur-6849 No description available WB:WBGene00169282 21ur-14051 No description available WB:WBGene00169283 21ur-7418 No description available WB:WBGene00169284 21ur-10802 No description available WB:WBGene00169285 21ur-13045 No description available WB:WBGene00169286 21ur-11016 No description available WB:WBGene00169287 21ur-8111 Is affected by eat-2 and set-2 based on microarray and RNA-seq studies. WB:WBGene00169288 21ur-6350 No description available WB:WBGene00169289 21ur-10774 No description available WB:WBGene00169290 21ur-13705 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169291 21ur-9850 No description available WB:WBGene00169292 21ur-14704 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169293 21ur-7027 No description available WB:WBGene00169294 21ur-12819 No description available WB:WBGene00169295 21ur-15295 No description available WB:WBGene00169296 21ur-6782 No description available WB:WBGene00169297 21ur-10743 No description available WB:WBGene00169298 21ur-12194 No description available WB:WBGene00169299 21ur-12726 No description available WB:WBGene00169300 21ur-14002 No description available WB:WBGene00169301 21ur-13447 No description available WB:WBGene00169302 21ur-15260 No description available WB:WBGene00169303 21ur-14705 No description available WB:WBGene00169304 21ur-8139 No description available WB:WBGene00169305 21ur-7550 No description available WB:WBGene00169306 21ur-10843 No description available WB:WBGene00169307 21ur-14955 No description available WB:WBGene00169308 21ur-9678 No description available WB:WBGene00169309 21ur-12893 No description available WB:WBGene00169310 21ur-7659 No description available WB:WBGene00169311 21ur-8388 No description available WB:WBGene00169312 21ur-8401 No description available WB:WBGene00169313 21ur-13134 No description available WB:WBGene00169314 21ur-14555 No description available WB:WBGene00169315 21ur-14183 No description available WB:WBGene00169316 21ur-6779 No description available WB:WBGene00169317 21ur-13836 No description available WB:WBGene00169318 21ur-9655 No description available WB:WBGene00169319 21ur-13902 No description available WB:WBGene00169320 21ur-12090 No description available WB:WBGene00169321 21ur-11974 No description available WB:WBGene00169322 21ur-11674 No description available WB:WBGene00169323 21ur-14654 No description available WB:WBGene00169324 21ur-7202 No description available WB:WBGene00169325 21ur-13401 No description available WB:WBGene00169326 21ur-13071 No description available WB:WBGene00169327 21ur-6776 No description available WB:WBGene00169328 21ur-13920 No description available WB:WBGene00169329 21ur-11946 No description available WB:WBGene00169330 21ur-12487 No description available WB:WBGene00169331 21ur-7736 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00169332 21ur-7209 No description available WB:WBGene00169333 21ur-11358 No description available WB:WBGene00169334 21ur-11070 No description available WB:WBGene00169335 21ur-5882 No description available WB:WBGene00169336 21ur-13372 No description available WB:WBGene00169337 21ur-13466 No description available WB:WBGene00169338 21ur-13093 No description available WB:WBGene00169339 21ur-14775 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169340 21ur-12169 No description available WB:WBGene00169341 21ur-13315 No description available WB:WBGene00169342 21ur-11315 No description available WB:WBGene00169343 21ur-7281 No description available WB:WBGene00169344 21ur-14991 No description available WB:WBGene00169345 21ur-8300 No description available WB:WBGene00169346 21ur-11156 No description available WB:WBGene00169347 21ur-15411 No description available WB:WBGene00169348 21ur-14475 No description available WB:WBGene00169349 21ur-10416 No description available WB:WBGene00169350 21ur-9501 No description available WB:WBGene00169351 21ur-14407 No description available WB:WBGene00169352 21ur-13982 No description available WB:WBGene00169353 21ur-13163 No description available WB:WBGene00169354 21ur-10379 No description available WB:WBGene00169355 21ur-11733 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169356 21ur-12416 No description available WB:WBGene00169357 21ur-9578 Enriched in neurons based on RNA-seq studies. WB:WBGene00169358 21ur-9017 No description available WB:WBGene00169359 21ur-12407 No description available WB:WBGene00169360 21ur-8713 No description available WB:WBGene00169361 21ur-14733 Enriched in neurons based on RNA-seq studies. WB:WBGene00169362 21ur-12769 No description available WB:WBGene00169363 21ur-12455 No description available WB:WBGene00169364 21ur-14986 No description available WB:WBGene00169365 21ur-11182 No description available WB:WBGene00169366 21ur-8219 Is affected by set-2 based on RNA-seq studies. WB:WBGene00169367 21ur-12446 No description available WB:WBGene00169368 21ur-14782 No description available WB:WBGene00169369 21ur-11326 No description available WB:WBGene00169370 21ur-8715 No description available WB:WBGene00169371 21ur-13807 No description available WB:WBGene00169372 21ur-8438 No description available WB:WBGene00169373 21ur-13023 No description available WB:WBGene00169374 21ur-6700 No description available WB:WBGene00169375 21ur-13221 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169376 21ur-9059 Enriched in neurons based on RNA-seq studies. WB:WBGene00169377 21ur-14770 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169378 21ur-7964 No description available WB:WBGene00169379 21ur-15493 No description available WB:WBGene00169380 21ur-8357 No description available WB:WBGene00169381 21ur-9194 No description available WB:WBGene00169382 21ur-12970 No description available WB:WBGene00169383 21ur-9225 Enriched in neurons based on RNA-seq studies. WB:WBGene00169384 21ur-7803 No description available WB:WBGene00169385 21ur-12858 No description available WB:WBGene00169386 21ur-10821 No description available WB:WBGene00169387 21ur-14464 No description available WB:WBGene00169388 21ur-12523 No description available WB:WBGene00169389 21ur-11369 No description available WB:WBGene00169390 21ur-9426 No description available WB:WBGene00169391 21ur-10962 No description available WB:WBGene00169392 21ur-8209 No description available WB:WBGene00169393 21ur-6401 No description available WB:WBGene00169394 21ur-9722 No description available WB:WBGene00169395 21ur-14998 No description available WB:WBGene00169396 21ur-13480 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00169397 21ur-10069 No description available WB:WBGene00169398 21ur-5673 No description available WB:WBGene00169399 21ur-8014 Enriched in neurons based on RNA-seq studies. WB:WBGene00169401 21ur-5701 No description available WB:WBGene00169402 21ur-10077 No description available WB:WBGene00169403 21ur-8925 No description available WB:WBGene00169404 21ur-14255 No description available WB:WBGene00169405 21ur-11459 No description available WB:WBGene00169406 21ur-7432 No description available WB:WBGene00169407 21ur-6047 No description available WB:WBGene00169408 21ur-13258 No description available WB:WBGene00169409 21ur-11747 No description available WB:WBGene00169410 21ur-6610 No description available WB:WBGene00169411 21ur-7626 No description available WB:WBGene00169412 21ur-12371 No description available WB:WBGene00169413 21ur-5751 No description available WB:WBGene00169414 21ur-13489 No description available WB:WBGene00169415 21ur-7922 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00169416 21ur-10118 No description available WB:WBGene00169417 21ur-11426 No description available WB:WBGene00169418 21ur-9522 No description available WB:WBGene00169419 21ur-10827 No description available WB:WBGene00169420 21ur-5891 No description available WB:WBGene00169421 21ur-13187 No description available WB:WBGene00169422 21ur-15323 No description available WB:WBGene00169423 21ur-9605 No description available WB:WBGene00169424 21ur-8467 No description available WB:WBGene00169425 21ur-6215 Enriched in neurons based on RNA-seq studies. WB:WBGene00169426 21ur-15109 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00169427 21ur-13248 No description available WB:WBGene00169428 21ur-8424 No description available WB:WBGene00169429 21ur-7699 No description available WB:WBGene00169430 21ur-11866 No description available WB:WBGene00169431 21ur-10597 No description available WB:WBGene00169432 21ur-14375 Enriched in neurons based on RNA-seq studies. WB:WBGene00169433 21ur-5462 No description available WB:WBGene00169434 21ur-8265 No description available WB:WBGene00169435 21ur-7823 No description available WB:WBGene00169436 21ur-12055 No description available WB:WBGene00169437 21ur-10043 No description available WB:WBGene00169438 21ur-10890 No description available WB:WBGene00169439 21ur-13388 No description available WB:WBGene00169440 21ur-13550 No description available WB:WBGene00169441 21ur-10307 No description available WB:WBGene00169442 21ur-8745 No description available WB:WBGene00169443 21ur-15436 No description available WB:WBGene00169444 21ur-11611 Is affected by eat-2 based on microarray studies. WB:WBGene00169445 21ur-7197 No description available WB:WBGene00169446 21ur-14527 No description available WB:WBGene00169447 21ur-9023 No description available WB:WBGene00169448 21ur-15262 No description available WB:WBGene00169449 21ur-15678 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169450 21ur-9496 No description available WB:WBGene00169451 21ur-15058 No description available WB:WBGene00169452 21ur-10389 No description available WB:WBGene00169453 21ur-8705 No description available WB:WBGene00169454 21ur-10965 No description available WB:WBGene00169455 21ur-7273 No description available WB:WBGene00169456 21ur-10427 No description available WB:WBGene00169457 21ur-8794 No description available WB:WBGene00169458 21ur-10245 No description available WB:WBGene00169459 21ur-13276 No description available WB:WBGene00169460 21ur-15333 No description available WB:WBGene00169461 21ur-10139 No description available WB:WBGene00169462 21ur-12039 No description available WB:WBGene00169463 21ur-7316 No description available WB:WBGene00169464 21ur-11723 Is affected by eat-2 based on microarray studies. WB:WBGene00169465 21ur-13243 No description available WB:WBGene00169466 21ur-6449 No description available WB:WBGene00169467 21ur-9204 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00169468 21ur-15681 No description available WB:WBGene00169469 21ur-12995 No description available WB:WBGene00169470 21ur-7308 No description available WB:WBGene00169471 21ur-8172 No description available WB:WBGene00169472 21ur-6399 No description available WB:WBGene00169473 21ur-12096 No description available WB:WBGene00169474 21ur-5510 No description available WB:WBGene00169475 21ur-6050 No description available WB:WBGene00169476 21ur-7233 No description available WB:WBGene00169477 21ur-7047 No description available WB:WBGene00169478 21ur-11784 No description available WB:WBGene00169479 21ur-12739 No description available WB:WBGene00169480 21ur-11003 No description available WB:WBGene00169481 21ur-9442 No description available WB:WBGene00169482 21ur-8367 No description available WB:WBGene00169483 21ur-6807 No description available WB:WBGene00169484 21ur-8458 Is affected by daf-2 based on microarray studies. WB:WBGene00169485 21ur-14659 No description available WB:WBGene00169486 21ur-13200 No description available WB:WBGene00169487 21ur-10213 No description available WB:WBGene00169488 21ur-8779 No description available WB:WBGene00169489 21ur-14136 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00169490 21ur-10541 No description available WB:WBGene00169491 21ur-5592 No description available WB:WBGene00169492 21ur-13507 No description available WB:WBGene00169493 21ur-8180 No description available WB:WBGene00169494 21ur-11945 No description available WB:WBGene00169495 21ur-10644 No description available WB:WBGene00169496 21ur-5726 No description available WB:WBGene00169497 21ur-12698 No description available WB:WBGene00169498 21ur-14620 Is affected by daf-2 based on microarray studies. WB:WBGene00169499 21ur-7892 No description available WB:WBGene00169500 21ur-6347 No description available WB:WBGene00169501 21ur-10071 No description available WB:WBGene00169502 21ur-9353 No description available WB:WBGene00169503 21ur-14278 No description available WB:WBGene00169504 21ur-13547 No description available WB:WBGene00169505 21ur-8532 No description available WB:WBGene00169506 21ur-10899 No description available WB:WBGene00169507 21ur-14383 No description available WB:WBGene00169508 21ur-10403 No description available WB:WBGene00169509 21ur-12777 No description available WB:WBGene00169510 21ur-6741 No description available WB:WBGene00169511 21ur-10147 No description available WB:WBGene00169512 21ur-11576 No description available WB:WBGene00169513 21ur-9995 No description available WB:WBGene00169514 21ur-15671 No description available WB:WBGene00169515 21ur-14332 No description available WB:WBGene00169516 21ur-14766 No description available WB:WBGene00169517 21ur-15491 No description available WB:WBGene00169518 21ur-15104 No description available WB:WBGene00169519 21ur-15269 No description available WB:WBGene00169520 21ur-7011 Enriched in neurons based on RNA-seq studies. WB:WBGene00169521 21ur-15563 No description available WB:WBGene00169522 21ur-6515 Is affected by set-2 based on RNA-seq studies. WB:WBGene00169523 21ur-5588 No description available WB:WBGene00169524 21ur-8539 No description available WB:WBGene00169525 21ur-10154 Enriched in neurons based on RNA-seq studies. WB:WBGene00169526 21ur-9808 Enriched in neurons based on RNA-seq studies. WB:WBGene00169527 21ur-15428 No description available WB:WBGene00169528 21ur-15541 No description available WB:WBGene00169529 21ur-8845 No description available WB:WBGene00169530 21ur-8781 No description available WB:WBGene00169531 21ur-7899 No description available WB:WBGene00169532 21ur-13172 No description available WB:WBGene00169533 21ur-15471 No description available WB:WBGene00169534 21ur-14493 No description available WB:WBGene00169535 21ur-5621 No description available WB:WBGene00169536 21ur-5977 No description available WB:WBGene00169537 21ur-11910 No description available WB:WBGene00169538 21ur-10927 Is affected by let-418 and hlh-26 based on RNA-seq studies. WB:WBGene00169539 21ur-8988 No description available WB:WBGene00169540 21ur-13909 No description available WB:WBGene00169541 21ur-14763 No description available WB:WBGene00169542 21ur-9946 No description available WB:WBGene00169543 21ur-6585 No description available WB:WBGene00169544 21ur-5876 No description available WB:WBGene00169545 21ur-10487 No description available WB:WBGene00169546 21ur-5989 No description available WB:WBGene00169547 21ur-12198 No description available WB:WBGene00169548 21ur-7824 No description available WB:WBGene00169549 21ur-11776 No description available WB:WBGene00169550 21ur-11067 No description available WB:WBGene00169551 21ur-8408 No description available WB:WBGene00169552 21ur-12405 No description available WB:WBGene00169553 21ur-13744 No description available WB:WBGene00169554 21ur-6661 Is affected by chd-3 based on RNA-seq studies. WB:WBGene00169555 21ur-9114 No description available WB:WBGene00169556 21ur-6254 No description available WB:WBGene00169557 21ur-14542 No description available WB:WBGene00169558 21ur-12907 No description available WB:WBGene00169559 21ur-11390 No description available WB:WBGene00169560 21ur-5536 No description available WB:WBGene00169561 21ur-13694 No description available WB:WBGene00169562 21ur-7624 No description available WB:WBGene00169563 21ur-10474 No description available WB:WBGene00169564 21ur-6998 No description available WB:WBGene00169565 21ur-10180 No description available WB:WBGene00169566 21ur-6152 No description available WB:WBGene00169567 21ur-15276 No description available WB:WBGene00169568 21ur-11340 No description available WB:WBGene00169569 21ur-10910 No description available WB:WBGene00169570 21ur-9428 Enriched in neurons based on RNA-seq studies. WB:WBGene00169571 21ur-8155 No description available WB:WBGene00169572 21ur-14844 No description available WB:WBGene00169573 21ur-10731 No description available WB:WBGene00169574 21ur-10542 No description available WB:WBGene00169575 21ur-8349 No description available WB:WBGene00169576 21ur-11239 No description available WB:WBGene00169577 21ur-11126 No description available WB:WBGene00169578 21ur-7740 No description available WB:WBGene00169579 21ur-15035 No description available WB:WBGene00169580 21ur-14299 No description available WB:WBGene00169581 21ur-11454 No description available WB:WBGene00169582 21ur-10186 No description available WB:WBGene00169583 21ur-14673 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00169584 21ur-9339 No description available WB:WBGene00169585 21ur-15113 No description available WB:WBGene00169586 21ur-10513 No description available WB:WBGene00169587 21ur-11419 No description available WB:WBGene00169588 21ur-5601 No description available WB:WBGene00169589 21ur-14652 Is affected by set-2 based on RNA-seq studies. WB:WBGene00169590 21ur-6598 Is affected by damt-1 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00169591 21ur-8954 No description available WB:WBGene00169592 21ur-9006 No description available WB:WBGene00169593 21ur-15094 No description available WB:WBGene00169594 21ur-13215 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169595 21ur-14036 No description available WB:WBGene00169596 21ur-12509 No description available WB:WBGene00169597 21ur-11146 No description available WB:WBGene00169598 21ur-13677 No description available WB:WBGene00169599 21ur-8025 No description available WB:WBGene00169600 21ur-10911 No description available WB:WBGene00169601 21ur-10865 No description available WB:WBGene00169602 21ur-9272 No description available WB:WBGene00169603 21ur-10505 No description available WB:WBGene00169604 21ur-11988 No description available WB:WBGene00169605 21ur-9634 No description available WB:WBGene00169606 21ur-11397 No description available WB:WBGene00169607 21ur-9141 Enriched in neurons based on RNA-seq studies. WB:WBGene00169608 21ur-11835 No description available WB:WBGene00169609 21ur-5717 No description available WB:WBGene00169610 21ur-6564 No description available WB:WBGene00169611 21ur-13359 No description available WB:WBGene00169612 21ur-12823 No description available WB:WBGene00169613 21ur-12365 No description available WB:WBGene00169614 21ur-14575 No description available WB:WBGene00169615 21ur-14625 No description available WB:WBGene00169617 21ur-13384 No description available WB:WBGene00169618 21ur-9761 No description available WB:WBGene00169619 21ur-12635 No description available WB:WBGene00169620 21ur-15061 No description available WB:WBGene00169621 21ur-14973 No description available WB:WBGene00169622 21ur-11618 No description available WB:WBGene00169623 21ur-6748 No description available WB:WBGene00169624 21ur-13943 No description available WB:WBGene00169625 21ur-15310 Enriched in neurons based on RNA-seq studies. WB:WBGene00169626 21ur-14326 No description available WB:WBGene00169627 21ur-9827 No description available WB:WBGene00169628 21ur-10342 Enriched in neurons based on RNA-seq studies. WB:WBGene00169629 21ur-9619 No description available WB:WBGene00169630 21ur-8965 No description available WB:WBGene00169631 21ur-14353 No description available WB:WBGene00169632 21ur-12061 No description available WB:WBGene00169633 21ur-15396 Enriched in neurons based on RNA-seq studies. WB:WBGene00169634 21ur-13874 No description available WB:WBGene00169635 21ur-5774 No description available WB:WBGene00169636 21ur-10800 No description available WB:WBGene00169637 21ur-5945 No description available WB:WBGene00169638 21ur-9384 No description available WB:WBGene00169639 21ur-15242 No description available WB:WBGene00169640 21ur-11294 No description available WB:WBGene00169641 21ur-10715 No description available WB:WBGene00169642 21ur-9378 No description available WB:WBGene00169643 21ur-10382 No description available WB:WBGene00169644 21ur-7163 No description available WB:WBGene00169645 21ur-15490 No description available WB:WBGene00169646 21ur-11214 No description available WB:WBGene00169647 21ur-11028 No description available WB:WBGene00169648 21ur-13748 No description available WB:WBGene00169649 21ur-14079 Is affected by lem-2; emr-1; and hmg-3 based on RNA-seq studies. WB:WBGene00169650 21ur-7385 No description available WB:WBGene00169651 21ur-15254 No description available WB:WBGene00169652 21ur-10463 Enriched in neurons based on RNA-seq studies. WB:WBGene00169653 21ur-9154 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169654 21ur-14070 No description available WB:WBGene00169655 21ur-12395 No description available WB:WBGene00169656 21ur-10016 No description available WB:WBGene00169657 21ur-14789 No description available WB:WBGene00169658 21ur-6141 No description available WB:WBGene00169659 21ur-15228 No description available WB:WBGene00169660 21ur-10670 No description available WB:WBGene00169661 21ur-8168 No description available WB:WBGene00169662 21ur-13993 No description available WB:WBGene00169663 21ur-5467 No description available WB:WBGene00169664 21ur-7086 No description available WB:WBGene00169665 21ur-7366 No description available WB:WBGene00169666 21ur-8061 No description available WB:WBGene00169667 21ur-7446 No description available WB:WBGene00169668 21ur-9511 No description available WB:WBGene00169669 21ur-5982 Enriched in neurons based on RNA-seq studies. WB:WBGene00169670 21ur-8079 No description available WB:WBGene00169671 21ur-11597 No description available WB:WBGene00169672 21ur-10809 No description available WB:WBGene00169673 21ur-12077 No description available WB:WBGene00169674 21ur-15033 Is affected by emr-1; hmg-3; and spt-16 based on RNA-seq studies. WB:WBGene00169675 21ur-9908 No description available WB:WBGene00169676 21ur-7368 No description available WB:WBGene00169677 21ur-8677 Enriched in neurons based on RNA-seq studies. WB:WBGene00169678 21ur-13433 No description available WB:WBGene00169679 21ur-10755 No description available WB:WBGene00169680 21ur-5677 Is affected by spt-16 based on RNA-seq studies. WB:WBGene00169681 21ur-6015 Is affected by daf-2 based on microarray studies. WB:WBGene00169682 21ur-15633 No description available WB:WBGene00169683 21ur-15059 No description available WB:WBGene00169684 21ur-11716 No description available WB:WBGene00169685 21ur-11590 No description available WB:WBGene00169686 21ur-11435 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00169687 21ur-10161 No description available WB:WBGene00169688 21ur-11104 No description available WB:WBGene00169689 21ur-11756 No description available WB:WBGene00169690 21ur-10131 No description available WB:WBGene00169691 21ur-6239 No description available WB:WBGene00169692 21ur-10764 No description available WB:WBGene00169693 21ur-14693 No description available WB:WBGene00169694 21ur-7361 Enriched in neurons based on RNA-seq studies. WB:WBGene00169695 21ur-13802 No description available WB:WBGene00169696 21ur-9083 No description available WB:WBGene00169697 21ur-5563 No description available WB:WBGene00169698 21ur-6362 No description available WB:WBGene00169699 21ur-9463 No description available WB:WBGene00169700 21ur-9690 No description available WB:WBGene00169701 21ur-14661 No description available WB:WBGene00169702 21ur-13379 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00169703 21ur-6370 No description available WB:WBGene00169704 21ur-7976 No description available WB:WBGene00169705 21ur-15338 No description available WB:WBGene00169706 21ur-15120 No description available WB:WBGene00169707 21ur-10650 No description available WB:WBGene00169708 21ur-9718 Enriched in neurons based on RNA-seq studies. WB:WBGene00169709 21ur-5781 No description available WB:WBGene00169710 21ur-10629 No description available WB:WBGene00169711 21ur-11871 No description available WB:WBGene00169712 21ur-13659 No description available WB:WBGene00169713 21ur-11467 No description available WB:WBGene00169714 21ur-13583 No description available WB:WBGene00169715 21ur-8864 No description available WB:WBGene00169716 21ur-12081 No description available WB:WBGene00169717 21ur-7190 No description available WB:WBGene00169718 21ur-15577 No description available WB:WBGene00169719 21ur-8100 No description available WB:WBGene00169720 21ur-12842 No description available WB:WBGene00169721 21ur-14826 No description available WB:WBGene00169722 21ur-11032 No description available WB:WBGene00169723 21ur-10680 No description available WB:WBGene00169724 21ur-8751 No description available WB:WBGene00169725 21ur-14965 No description available WB:WBGene00169726 21ur-6428 No description available WB:WBGene00169727 21ur-11448 No description available WB:WBGene00169728 21ur-10201 No description available WB:WBGene00169729 21ur-8654 Enriched in neurons based on RNA-seq studies. WB:WBGene00169730 21ur-6767 No description available WB:WBGene00169731 21ur-11283 No description available WB:WBGene00169732 21ur-14748 No description available WB:WBGene00169733 21ur-11227 No description available WB:WBGene00169734 21ur-13267 Is affected by mrps-5 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00169735 21ur-12674 No description available WB:WBGene00169736 21ur-6170 No description available WB:WBGene00169737 21ur-13680 No description available WB:WBGene00169738 21ur-13631 No description available WB:WBGene00169739 21ur-12646 Enriched in neurons based on RNA-seq studies. WB:WBGene00169740 21ur-14838 No description available WB:WBGene00169741 21ur-7597 No description available WB:WBGene00169742 21ur-7739 No description available WB:WBGene00169743 21ur-11282 No description available WB:WBGene00169744 21ur-6652 No description available WB:WBGene00169745 21ur-14110 No description available WB:WBGene00169746 21ur-15389 No description available WB:WBGene00169747 21ur-8231 No description available WB:WBGene00169748 21ur-13398 No description available WB:WBGene00169749 21ur-14290 No description available WB:WBGene00169750 21ur-11097 No description available WB:WBGene00169751 21ur-8289 No description available WB:WBGene00169752 21ur-14502 No description available WB:WBGene00169753 21ur-10025 No description available WB:WBGene00169754 21ur-12240 No description available WB:WBGene00169755 21ur-6641 No description available WB:WBGene00169756 21ur-10641 No description available WB:WBGene00169757 21ur-15116 No description available WB:WBGene00169758 21ur-8616 No description available WB:WBGene00169759 21ur-7000 No description available WB:WBGene00169760 21ur-14547 No description available WB:WBGene00169761 21ur-6863 No description available WB:WBGene00169762 21ur-13127 No description available WB:WBGene00169763 21ur-9279 No description available WB:WBGene00169764 21ur-7374 No description available WB:WBGene00169765 21ur-5504 No description available WB:WBGene00169766 21ur-15207 No description available WB:WBGene00169767 21ur-9715 No description available WB:WBGene00169768 21ur-6396 Enriched in neurons based on RNA-seq studies. WB:WBGene00169769 21ur-12707 No description available WB:WBGene00169770 21ur-11043 No description available WB:WBGene00169771 21ur-6113 No description available WB:WBGene00169772 21ur-9413 No description available WB:WBGene00169773 21ur-11039 No description available WB:WBGene00169774 21ur-8393 No description available WB:WBGene00169775 21ur-13573 Is affected by daf-2 based on microarray studies. WB:WBGene00169776 21ur-8586 No description available WB:WBGene00169777 21ur-12378 No description available WB:WBGene00169778 21ur-5809 No description available WB:WBGene00169779 21ur-8259 No description available WB:WBGene00169780 21ur-8757 No description available WB:WBGene00169781 21ur-15504 No description available WB:WBGene00169782 21ur-6625 No description available WB:WBGene00169783 21ur-14153 No description available WB:WBGene00169784 21ur-10373 No description available WB:WBGene00169785 21ur-7213 No description available WB:WBGene00169786 21ur-6232 No description available WB:WBGene00169787 21ur-15190 No description available WB:WBGene00169788 21ur-11207 No description available WB:WBGene00169789 21ur-8933 No description available WB:WBGene00169790 21ur-15367 No description available WB:WBGene00169791 21ur-5903 No description available WB:WBGene00169792 21ur-10983 No description available WB:WBGene00169793 21ur-9581 No description available WB:WBGene00169794 21ur-5788 No description available WB:WBGene00169795 21ur-7643 No description available WB:WBGene00169796 21ur-9233 No description available WB:WBGene00169797 21ur-5857 No description available WB:WBGene00169798 21ur-15221 No description available WB:WBGene00169799 21ur-13237 No description available WB:WBGene00169800 21ur-13118 No description available WB:WBGene00169801 21ur-10621 No description available WB:WBGene00169802 21ur-13844 No description available WB:WBGene00169803 21ur-13077 No description available WB:WBGene00169804 21ur-7137 No description available WB:WBGene00169805 21ur-11523 No description available WB:WBGene00169806 21ur-12298 No description available WB:WBGene00169807 21ur-7788 No description available WB:WBGene00169808 21ur-11308 No description available WB:WBGene00169809 21ur-14315 No description available WB:WBGene00169810 21ur-7005 Enriched in neurons based on RNA-seq studies. WB:WBGene00169811 21ur-13595 No description available WB:WBGene00169812 21ur-6299 No description available WB:WBGene00169813 21ur-13370 No description available WB:WBGene00169814 21ur-13269 No description available WB:WBGene00169815 21ur-9700 No description available WB:WBGene00169816 21ur-6044 Enriched in neurons based on RNA-seq studies. WB:WBGene00169817 21ur-13168 No description available WB:WBGene00169818 21ur-6688 No description available WB:WBGene00169819 21ur-7505 No description available WB:WBGene00169820 21ur-8581 No description available WB:WBGene00169821 21ur-5586 No description available WB:WBGene00169822 21ur-14227 No description available WB:WBGene00169823 21ur-15047 No description available WB:WBGene00169824 21ur-13188 No description available WB:WBGene00169825 21ur-8915 No description available WB:WBGene00169826 21ur-15519 No description available WB:WBGene00169827 21ur-10659 No description available WB:WBGene00169828 21ur-9796 No description available WB:WBGene00169829 21ur-10093 No description available WB:WBGene00169830 21ur-5932 No description available WB:WBGene00169831 21ur-14362 No description available WB:WBGene00169832 21ur-6290 Enriched in neurons based on RNA-seq studies. WB:WBGene00169833 21ur-14614 No description available WB:WBGene00169834 21ur-6962 No description available WB:WBGene00169835 21ur-8043 No description available WB:WBGene00169836 21ur-11544 No description available WB:WBGene00169837 21ur-8605 Is affected by set-2 based on RNA-seq studies. WB:WBGene00169838 21ur-11646 No description available WB:WBGene00169839 21ur-11023 No description available WB:WBGene00169840 21ur-15214 No description available WB:WBGene00169841 21ur-15134 No description available WB:WBGene00169842 21ur-7571 No description available WB:WBGene00169843 21ur-13624 No description available WB:WBGene00169844 21ur-7034 No description available WB:WBGene00169845 21ur-9967 No description available WB:WBGene00169846 21ur-10165 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00169847 21ur-5544 No description available WB:WBGene00169848 21ur-7888 Is affected by lem-2; emr-1; and olrn-1 based on RNA-seq studies. WB:WBGene00169849 21ur-10814 No description available WB:WBGene00169850 21ur-14096 No description available WB:WBGene00169851 21ur-14454 No description available WB:WBGene00169852 21ur-7116 No description available WB:WBGene00169853 21ur-7590 No description available WB:WBGene00169854 21ur-7687 No description available WB:WBGene00169855 21ur-14222 No description available WB:WBGene00169856 21ur-6950 Enriched in neurons based on RNA-seq studies. WB:WBGene00169857 21ur-7948 No description available WB:WBGene00169858 21ur-8575 No description available WB:WBGene00169859 21ur-8879 No description available WB:WBGene00169860 21ur-15570 No description available WB:WBGene00169861 21ur-15279 Enriched in neurons based on RNA-seq studies. WB:WBGene00169862 21ur-10289 No description available WB:WBGene00169863 21ur-14863 No description available WB:WBGene00169864 21ur-12232 No description available WB:WBGene00169865 21ur-14488 No description available WB:WBGene00169866 21ur-13517 No description available WB:WBGene00169867 21ur-11480 No description available WB:WBGene00169868 21ur-10619 No description available WB:WBGene00169869 21ur-7142 No description available WB:WBGene00169870 21ur-12030 No description available WB:WBGene00169871 21ur-5576 No description available WB:WBGene00169872 21ur-6136 No description available WB:WBGene00169873 21ur-13528 No description available WB:WBGene00169874 21ur-12764 No description available WB:WBGene00169875 21ur-7983 No description available WB:WBGene00169876 21ur-7783 No description available WB:WBGene00169877 21ur-8005 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00169878 21ur-11000 No description available WB:WBGene00169879 21ur-9550 Is affected by eat-2 based on microarray studies. WB:WBGene00169880 21ur-11359 No description available WB:WBGene00169881 21ur-13111 No description available WB:WBGene00169882 21ur-15009 No description available WB:WBGene00169883 21ur-13451 No description available WB:WBGene00169884 21ur-13649 No description available WB:WBGene00169885 21ur-12147 No description available WB:WBGene00169886 21ur-6419 No description available WB:WBGene00169887 21ur-12438 No description available WB:WBGene00169888 21ur-12561 No description available WB:WBGene00169889 21ur-5659 No description available WB:WBGene00169890 21ur-8670 No description available WB:WBGene00169891 21ur-15536 No description available WB:WBGene00169892 21ur-14522 No description available WB:WBGene00169893 21ur-13978 No description available WB:WBGene00169894 21ur-6335 No description available WB:WBGene00169895 21ur-11511 No description available WB:WBGene00169896 21ur-14831 No description available WB:WBGene00169897 21ur-15480 No description available WB:WBGene00169898 21ur-13452 No description available WB:WBGene00169899 21ur-7941 Enriched in neurons based on RNA-seq studies. WB:WBGene00169900 21ur-14850 No description available WB:WBGene00169901 21ur-9785 No description available WB:WBGene00169902 21ur-14485 No description available WB:WBGene00169903 21ur-11625 Enriched in neurons based on RNA-seq studies. WB:WBGene00169904 21ur-9557 No description available WB:WBGene00169905 21ur-7869 Enriched in neurons based on RNA-seq studies. WB:WBGene00169906 21ur-15657 No description available WB:WBGene00169907 21ur-6410 No description available WB:WBGene00169908 21ur-14105 No description available WB:WBGene00169909 21ur-10685 No description available WB:WBGene00169910 21ur-13961 No description available WB:WBGene00169911 21ur-12223 No description available WB:WBGene00169912 21ur-10615 No description available WB:WBGene00169913 21ur-9244 No description available WB:WBGene00169914 21ur-13914 No description available WB:WBGene00169915 21ur-14523 No description available WB:WBGene00169916 21ur-13947 No description available WB:WBGene00169917 21ur-9322 No description available WB:WBGene00169918 21ur-15197 No description available WB:WBGene00169919 21ur-14124 No description available WB:WBGene00169920 21ur-6617 No description available WB:WBGene00169921 21ur-8034 No description available WB:WBGene00169922 21ur-8216 No description available WB:WBGene00169923 21ur-9287 No description available WB:WBGene00169924 21ur-11726 No description available WB:WBGene00169925 21ur-11487 No description available WB:WBGene00169926 21ur-6058 No description available WB:WBGene00169927 21ur-7424 No description available WB:WBGene00169928 21ur-10624 No description available WB:WBGene00169929 21ur-7586 No description available WB:WBGene00169930 21ur-15042 No description available WB:WBGene00169931 21ur-7052 No description available WB:WBGene00169932 21ur-13403 No description available WB:WBGene00169933 21ur-12026 No description available WB:WBGene00169934 21ur-6987 No description available WB:WBGene00169935 21ur-11515 No description available WB:WBGene00169936 21ur-8241 No description available WB:WBGene00169937 21ur-9628 No description available WB:WBGene00169938 21ur-7068 No description available WB:WBGene00169939 21ur-9872 No description available WB:WBGene00169940 21ur-13251 No description available WB:WBGene00169941 21ur-8556 No description available WB:WBGene00169942 21ur-9483 No description available WB:WBGene00169943 21ur-14496 No description available WB:WBGene00169944 21ur-12617 No description available WB:WBGene00169946 21ur-7707 No description available WB:WBGene00169947 21ur-8644 No description available WB:WBGene00169948 21ur-8496 No description available WB:WBGene00169949 21ur-8896 No description available WB:WBGene00169950 21ur-9437 No description available WB:WBGene00169951 21ur-7715 No description available WB:WBGene00169952 21ur-11257 Enriched in neurons based on RNA-seq studies. WB:WBGene00169953 21ur-13650 No description available WB:WBGene00169954 21ur-13784 No description available WB:WBGene00169955 21ur-12210 No description available WB:WBGene00169956 21ur-10530 No description available WB:WBGene00169957 21ur-15015 No description available WB:WBGene00169958 21ur-15555 No description available WB:WBGene00169959 21ur-12390 No description available WB:WBGene00169960 21ur-10610 No description available WB:WBGene00169961 21ur-11019 No description available WB:WBGene00169962 21ur-7612 No description available WB:WBGene00169963 21ur-10003 No description available WB:WBGene00169964 21ur-13067 No description available WB:WBGene00169965 21ur-14311 No description available WB:WBGene00169966 21ur-15301 No description available WB:WBGene00169967 21ur-8854 No description available WB:WBGene00169968 21ur-12699 No description available WB:WBGene00169969 21ur-8319 No description available WB:WBGene00169970 21ur-12839 No description available WB:WBGene00169971 21ur-9867 No description available WB:WBGene00169972 21ur-11799 No description available WB:WBGene00169973 21ur-9960 No description available WB:WBGene00169974 21ur-14803 No description available WB:WBGene00169975 21ur-9534 No description available WB:WBGene00169976 21ur-10858 No description available WB:WBGene00169977 21ur-7437 No description available WB:WBGene00169978 21ur-10525 No description available WB:WBGene00169979 21ur-14010 No description available WB:WBGene00169980 21ur-15200 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00169981 21ur-13871 No description available WB:WBGene00169982 21ur-14331 No description available WB:WBGene00169983 21ur-14308 No description available WB:WBGene00169984 21ur-15460 No description available WB:WBGene00169985 21ur-6737 No description available WB:WBGene00169986 21ur-9137 No description available WB:WBGene00169987 21ur-15487 No description available WB:WBGene00169988 21ur-14950 No description available WB:WBGene00169989 21ur-14801 No description available WB:WBGene00169990 21ur-12928 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00169991 21ur-12986 No description available WB:WBGene00169992 21ur-12428 No description available WB:WBGene00169993 21ur-7254 No description available WB:WBGene00169994 21ur-14286 No description available WB:WBGene00169995 21ur-9977 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00169996 21ur-6486 No description available WB:WBGene00169997 21ur-8814 No description available WB:WBGene00169998 21ur-11250 Enriched in neurons based on RNA-seq studies. WB:WBGene00169999 21ur-15377 No description available WB:WBGene00170000 21ur-14168 No description available WB:WBGene00170001 21ur-11696 No description available WB:WBGene00170002 21ur-6185 No description available WB:WBGene00170003 21ur-9481 No description available WB:WBGene00170004 21ur-7875 No description available WB:WBGene00170005 21ur-11960 No description available WB:WBGene00170006 21ur-11090 No description available WB:WBGene00170007 21ur-8382 No description available WB:WBGene00170008 21ur-6472 No description available WB:WBGene00170009 21ur-13143 No description available WB:WBGene00170010 21ur-13704 No description available WB:WBGene00170011 21ur-8068 Is affected by daf-2 based on microarray studies. WB:WBGene00170012 21ur-9697 No description available WB:WBGene00170013 21ur-11818 No description available WB:WBGene00170014 21ur-9874 No description available WB:WBGene00170015 21ur-11060 No description available WB:WBGene00170016 21ur-10854 No description available WB:WBGene00170017 21ur-14534 No description available WB:WBGene00170018 21ur-7127 No description available WB:WBGene00170019 21ur-5790 No description available WB:WBGene00170020 21ur-13894 No description available WB:WBGene00170021 21ur-12770 No description available WB:WBGene00170022 21ur-9926 No description available WB:WBGene00170023 21ur-7992 No description available WB:WBGene00170024 21ur-8293 No description available WB:WBGene00170025 21ur-13641 No description available WB:WBGene00170026 21ur-11902 No description available WB:WBGene00170027 21ur-5565 No description available WB:WBGene00170028 21ur-7064 No description available WB:WBGene00170029 21ur-7429 No description available WB:WBGene00170030 21ur-8851 No description available WB:WBGene00170031 21ur-12788 No description available WB:WBGene00170032 21ur-14123 No description available WB:WBGene00170033 21ur-15465 No description available WB:WBGene00170034 21ur-6981 No description available WB:WBGene00170035 21ur-11383 No description available WB:WBGene00170036 21ur-6488 No description available WB:WBGene00170037 21ur-7809 No description available WB:WBGene00170038 21ur-14093 No description available WB:WBGene00170039 21ur-13063 No description available WB:WBGene00170040 21ur-6242 No description available WB:WBGene00170041 21ur-14759 No description available WB:WBGene00170042 21ur-8351 No description available WB:WBGene00170043 21ur-9740 No description available WB:WBGene00170044 21ur-8320 No description available WB:WBGene00170045 21ur-9355 No description available WB:WBGene00170046 21ur-9499 No description available WB:WBGene00170047 21ur-8048 No description available WB:WBGene00170048 21ur-7125 No description available WB:WBGene00170049 21ur-12637 No description available WB:WBGene00170050 21ur-12597 No description available WB:WBGene00170051 21ur-10812 No description available WB:WBGene00170052 21ur-5582 No description available WB:WBGene00170053 21ur-13407 No description available WB:WBGene00170054 21ur-14514 No description available WB:WBGene00170055 21ur-8551 No description available WB:WBGene00170056 21ur-13870 No description available WB:WBGene00170057 21ur-9284 No description available WB:WBGene00170058 21ur-11350 No description available WB:WBGene00170059 21ur-5725 No description available WB:WBGene00170060 21ur-15689 No description available WB:WBGene00170061 21ur-12181 No description available WB:WBGene00170062 21ur-7038 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00170063 21ur-10267 No description available WB:WBGene00170064 21ur-8065 No description available WB:WBGene00170065 21ur-11330 No description available WB:WBGene00170066 21ur-11020 No description available WB:WBGene00170067 21ur-9395 No description available WB:WBGene00170068 21ur-8676 No description available WB:WBGene00170069 21ur-12643 No description available WB:WBGene00170070 21ur-8566 No description available WB:WBGene00170071 21ur-10845 No description available WB:WBGene00170072 21ur-6340 No description available WB:WBGene00170073 21ur-6973 No description available WB:WBGene00170074 21ur-9034 No description available WB:WBGene00170075 21ur-14861 No description available WB:WBGene00170076 21ur-14284 No description available WB:WBGene00170077 21ur-8858 No description available WB:WBGene00170078 21ur-13933 Enriched in neurons based on RNA-seq studies. WB:WBGene00170079 21ur-7320 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00170080 21ur-9299 No description available WB:WBGene00170081 21ur-5620 No description available WB:WBGene00170082 21ur-9626 No description available WB:WBGene00170083 21ur-6351 No description available WB:WBGene00170084 21ur-5849 No description available WB:WBGene00170085 21ur-9905 No description available WB:WBGene00170086 21ur-14721 No description available WB:WBGene00170087 21ur-9078 No description available WB:WBGene00170088 21ur-9435 No description available WB:WBGene00170089 21ur-9035 No description available WB:WBGene00170090 21ur-11627 No description available WB:WBGene00170091 21ur-11661 No description available WB:WBGene00170092 21ur-15135 No description available WB:WBGene00170093 21ur-8874 No description available WB:WBGene00170094 21ur-9488 No description available WB:WBGene00170095 21ur-11256 No description available WB:WBGene00170096 21ur-13899 No description available WB:WBGene00170097 21ur-9653 No description available WB:WBGene00170098 21ur-13860 No description available WB:WBGene00170099 21ur-12153 No description available WB:WBGene00170100 21ur-6284 Enriched in neurons based on RNA-seq studies. WB:WBGene00170101 21ur-8015 No description available WB:WBGene00170102 21ur-15544 No description available WB:WBGene00170103 21ur-7310 No description available WB:WBGene00170104 21ur-10522 No description available WB:WBGene00170105 21ur-11543 No description available WB:WBGene00170106 21ur-9400 No description available WB:WBGene00170107 21ur-11899 No description available WB:WBGene00170108 21ur-15569 No description available WB:WBGene00170109 21ur-10506 No description available WB:WBGene00170110 21ur-12250 No description available WB:WBGene00170111 21ur-14102 No description available WB:WBGene00170112 21ur-14819 No description available WB:WBGene00170113 21ur-13867 No description available WB:WBGene00170114 21ur-8549 No description available WB:WBGene00170115 21ur-7703 No description available WB:WBGene00170116 21ur-11236 No description available WB:WBGene00170117 21ur-14084 No description available WB:WBGene00170118 21ur-7846 No description available WB:WBGene00170119 21ur-9211 No description available WB:WBGene00170120 21ur-9241 No description available WB:WBGene00170121 21ur-13956 Enriched in neurons based on RNA-seq studies. Is affected by met-2 based on RNA-seq studies. WB:WBGene00170122 21ur-8590 No description available WB:WBGene00170123 21ur-14521 No description available WB:WBGene00170124 21ur-13879 No description available WB:WBGene00170125 21ur-11036 No description available WB:WBGene00170126 21ur-13577 No description available WB:WBGene00170127 21ur-14841 No description available WB:WBGene00170128 21ur-9007 No description available WB:WBGene00170129 21ur-7422 Enriched in neurons based on RNA-seq studies. WB:WBGene00170130 21ur-12189 No description available WB:WBGene00170131 21ur-7585 Enriched in neurons based on RNA-seq studies. WB:WBGene00170132 21ur-9604 No description available WB:WBGene00170133 21ur-13178 No description available WB:WBGene00170134 21ur-6187 No description available WB:WBGene00170135 21ur-11029 No description available WB:WBGene00170136 21ur-11874 No description available WB:WBGene00170137 21ur-13711 No description available WB:WBGene00170138 21ur-8021 Enriched in neurons based on RNA-seq studies. WB:WBGene00170139 21ur-11223 No description available WB:WBGene00170140 21ur-9281 No description available WB:WBGene00170141 21ur-13514 No description available WB:WBGene00170142 21ur-10001 No description available WB:WBGene00170143 21ur-8571 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00170144 21ur-10388 No description available WB:WBGene00170145 21ur-12592 No description available WB:WBGene00170146 21ur-10625 No description available WB:WBGene00170147 21ur-5909 No description available WB:WBGene00170148 21ur-7251 No description available WB:WBGene00170149 21ur-11890 No description available WB:WBGene00170150 21ur-11317 No description available WB:WBGene00170151 21ur-15513 No description available WB:WBGene00170152 21ur-13274 Is affected by lem-2 based on RNA-seq studies. WB:WBGene00170153 21ur-13104 No description available WB:WBGene00170154 21ur-7192 No description available WB:WBGene00170155 21ur-13456 Enriched in neurons based on RNA-seq studies. WB:WBGene00170156 21ur-8576 No description available WB:WBGene00170157 21ur-9760 No description available WB:WBGene00170158 21ur-12149 No description available WB:WBGene00170159 21ur-11063 No description available WB:WBGene00170160 21ur-10860 No description available WB:WBGene00170161 21ur-14265 No description available WB:WBGene00170162 21ur-5653 Enriched in neurons based on RNA-seq studies. WB:WBGene00170163 21ur-11002 No description available WB:WBGene00170164 21ur-15017 No description available WB:WBGene00170165 21ur-11909 No description available WB:WBGene00170166 21ur-12038 No description available WB:WBGene00170167 21ur-6055 No description available WB:WBGene00170168 21ur-13455 Is affected by daf-2 based on microarray studies. WB:WBGene00170169 21ur-6607 No description available WB:WBGene00170170 21ur-8763 No description available WB:WBGene00170171 21ur-13859 No description available WB:WBGene00170172 21ur-8334 No description available WB:WBGene00170173 21ur-11895 No description available WB:WBGene00170174 21ur-7999 No description available WB:WBGene00170175 21ur-13137 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00170176 21ur-9234 No description available WB:WBGene00170177 21ur-11900 No description available WB:WBGene00170178 21ur-9015 No description available WB:WBGene00170179 21ur-10333 No description available WB:WBGene00170180 21ur-11882 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00170181 21ur-5830 No description available WB:WBGene00170182 21ur-10551 No description available WB:WBGene00170183 21ur-12614 No description available WB:WBGene00170184 21ur-6018 Enriched in neurons based on RNA-seq studies. WB:WBGene00170185 21ur-11118 Enriched in neurons based on RNA-seq studies. WB:WBGene00170186 21ur-6414 No description available WB:WBGene00170187 21ur-7723 No description available WB:WBGene00170188 21ur-5962 No description available WB:WBGene00170189 21ur-8332 No description available WB:WBGene00170190 21ur-7973 No description available WB:WBGene00170191 21ur-9680 No description available WB:WBGene00170192 21ur-15365 Enriched in neurons based on RNA-seq studies. WB:WBGene00170193 21ur-7138 No description available WB:WBGene00170194 21ur-8373 No description available WB:WBGene00170195 21ur-9248 No description available WB:WBGene00170196 21ur-14967 No description available WB:WBGene00170197 21ur-5860 No description available WB:WBGene00170198 21ur-8028 No description available WB:WBGene00170199 21ur-11465 No description available WB:WBGene00170200 21ur-8317 No description available WB:WBGene00170201 21ur-12266 No description available WB:WBGene00170202 21ur-13699 No description available WB:WBGene00170203 21ur-11735 No description available WB:WBGene00170204 21ur-10981 No description available WB:WBGene00170205 21ur-13592 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00170206 21ur-11429 No description available WB:WBGene00170207 21ur-15203 No description available WB:WBGene00170208 21ur-13891 No description available WB:WBGene00170209 21ur-6635 No description available WB:WBGene00170210 21ur-12997 No description available WB:WBGene00170211 21ur-14666 Enriched in neurons based on RNA-seq studies. WB:WBGene00170212 21ur-5807 No description available WB:WBGene00170213 21ur-14902 Enriched in neurons based on RNA-seq studies. WB:WBGene00170214 21ur-6382 No description available WB:WBGene00170215 21ur-10656 No description available WB:WBGene00170216 21ur-13994 No description available WB:WBGene00170217 21ur-5990 No description available WB:WBGene00170218 21ur-11367 No description available WB:WBGene00170219 21ur-9964 No description available WB:WBGene00170220 21ur-12291 No description available WB:WBGene00170221 21ur-11044 No description available WB:WBGene00170222 21ur-13205 No description available WB:WBGene00170223 21ur-11428 No description available WB:WBGene00170224 21ur-10976 No description available WB:WBGene00170225 21ur-7592 No description available WB:WBGene00170226 21ur-5824 No description available WB:WBGene00170227 21ur-6637 No description available WB:WBGene00170228 21ur-8754 No description available WB:WBGene00170229 21ur-10476 No description available WB:WBGene00170230 21ur-14569 No description available WB:WBGene00170231 21ur-8640 No description available WB:WBGene00170232 21ur-14518 No description available WB:WBGene00170233 21ur-7145 No description available WB:WBGene00170234 21ur-7617 No description available WB:WBGene00170235 21ur-8889 No description available WB:WBGene00170236 21ur-11265 No description available WB:WBGene00170237 21ur-15122 No description available WB:WBGene00170238 21ur-9265 No description available WB:WBGene00170239 21ur-9200 No description available WB:WBGene00170240 21ur-10310 No description available WB:WBGene00170241 21ur-11717 No description available WB:WBGene00170242 21ur-11092 No description available WB:WBGene00170243 21ur-6032 Enriched in neurons based on RNA-seq studies. WB:WBGene00170244 21ur-9623 No description available WB:WBGene00170245 21ur-10666 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00170246 21ur-6957 No description available WB:WBGene00170247 21ur-7077 No description available WB:WBGene00170248 21ur-8409 No description available WB:WBGene00170249 21ur-12352 No description available WB:WBGene00170250 21ur-9993 No description available WB:WBGene00170251 21ur-14590 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00170252 21ur-14807 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00170253 21ur-15161 No description available WB:WBGene00170254 21ur-12609 No description available WB:WBGene00170255 21ur-8926 No description available WB:WBGene00170256 21ur-12359 No description available WB:WBGene00170257 21ur-12701 No description available WB:WBGene00170258 21ur-6092 No description available WB:WBGene00170259 21ur-13846 No description available WB:WBGene00170260 21ur-5935 No description available WB:WBGene00170261 21ur-6043 No description available WB:WBGene00170262 21ur-9345 No description available WB:WBGene00170263 21ur-11497 No description available WB:WBGene00170264 21ur-14116 No description available WB:WBGene00170265 21ur-10049 No description available WB:WBGene00170266 21ur-6294 No description available WB:WBGene00170267 21ur-9300 No description available WB:WBGene00170268 21ur-13524 No description available WB:WBGene00170269 21ur-10187 No description available WB:WBGene00170270 21ur-10683 No description available WB:WBGene00170271 21ur-8073 No description available WB:WBGene00170272 21ur-8031 No description available WB:WBGene00170273 21ur-13852 No description available WB:WBGene00170274 21ur-9067 No description available WB:WBGene00170275 21ur-15642 No description available WB:WBGene00170276 21ur-14078 No description available WB:WBGene00170277 21ur-13186 No description available WB:WBGene00170278 21ur-13632 No description available WB:WBGene00170279 21ur-5575 No description available WB:WBGene00170280 21ur-14451 No description available WB:WBGene00170281 21ur-5914 No description available WB:WBGene00170282 21ur-7734 No description available WB:WBGene00170283 21ur-7056 No description available WB:WBGene00170284 21ur-12398 No description available WB:WBGene00170285 21ur-8346 No description available WB:WBGene00170286 21ur-13374 No description available WB:WBGene00170287 21ur-5634 No description available WB:WBGene00170288 21ur-10850 No description available WB:WBGene00170289 21ur-14960 No description available WB:WBGene00170290 21ur-15646 No description available WB:WBGene00170291 21ur-5900 No description available WB:WBGene00170292 21ur-9863 No description available WB:WBGene00170293 21ur-12439 No description available WB:WBGene00170294 21ur-8385 No description available WB:WBGene00170295 21ur-14109 No description available WB:WBGene00170296 21ur-11099 Is affected by meg-3; meg-4; and pptr-1 based on RNA-seq studies. WB:WBGene00170297 21ur-9461 No description available WB:WBGene00170298 21ur-9158 No description available WB:WBGene00170299 21ur-13683 No description available WB:WBGene00170300 21ur-12192 No description available WB:WBGene00170301 21ur-13678 No description available WB:WBGene00170302 21ur-12690 No description available WB:WBGene00170303 21ur-11778 No description available WB:WBGene00170304 21ur-15596 No description available WB:WBGene00170305 21ur-8561 Is affected by eat-2 based on microarray studies. WB:WBGene00170306 21ur-9719 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00170307 21ur-14910 Enriched in neurons based on RNA-seq studies. WB:WBGene00170308 21ur-10286 No description available WB:WBGene00170309 21ur-11691 No description available WB:WBGene00170310 21ur-14857 No description available WB:WBGene00170311 21ur-12022 No description available WB:WBGene00170312 21ur-9412 No description available WB:WBGene00170313 21ur-6648 No description available WB:WBGene00170314 21ur-13635 No description available WB:WBGene00170315 21ur-13072 No description available WB:WBGene00170316 21ur-9538 No description available WB:WBGene00170317 21ur-10102 No description available WB:WBGene00170318 21ur-12940 No description available WB:WBGene00170319 21ur-14317 No description available WB:WBGene00170320 21ur-15241 No description available WB:WBGene00170321 21ur-6729 No description available WB:WBGene00170322 21ur-9209 No description available WB:WBGene00170323 21ur-13642 No description available WB:WBGene00170324 21ur-13948 No description available WB:WBGene00170325 21ur-11783 No description available WB:WBGene00170326 21ur-11278 No description available WB:WBGene00170327 21ur-10163 No description available WB:WBGene00170328 21ur-10211 No description available WB:WBGene00170329 21ur-12965 No description available WB:WBGene00170330 21ur-7885 No description available WB:WBGene00170331 21ur-8817 No description available WB:WBGene00170332 21ur-10628 No description available WB:WBGene00170333 21ur-15385 No description available WB:WBGene00170334 21ur-11305 No description available WB:WBGene00170335 21ur-13885 Enriched in neurons based on RNA-seq studies. WB:WBGene00170336 21ur-8506 No description available WB:WBGene00170337 21ur-7373 No description available WB:WBGene00170338 21ur-9798 No description available WB:WBGene00170339 21ur-14677 No description available WB:WBGene00170340 21ur-14712 No description available WB:WBGene00170341 21ur-6902 No description available WB:WBGene00170342 21ur-8369 Enriched in neurons based on RNA-seq studies. WB:WBGene00170343 21ur-11535 Enriched in neurons based on RNA-seq studies. WB:WBGene00170344 21ur-12344 No description available WB:WBGene00170345 21ur-14817 No description available WB:WBGene00170346 21ur-8810 No description available WB:WBGene00170347 21ur-13129 No description available WB:WBGene00170348 21ur-14535 No description available WB:WBGene00170349 21ur-6733 No description available WB:WBGene00170350 21ur-6928 No description available WB:WBGene00170351 21ur-10940 No description available WB:WBGene00170352 21ur-6445 No description available WB:WBGene00170353 21ur-12925 No description available WB:WBGene00170354 21ur-14926 No description available WB:WBGene00170355 21ur-9337 No description available WB:WBGene00170356 21ur-10777 No description available WB:WBGene00170357 21ur-6697 No description available WB:WBGene00170358 21ur-14415 No description available WB:WBGene00170359 21ur-5695 No description available WB:WBGene00170360 21ur-14071 No description available WB:WBGene00170361 21ur-7527 No description available WB:WBGene00170362 21ur-14354 No description available WB:WBGene00170363 21ur-5976 No description available WB:WBGene00170364 21ur-9028 No description available WB:WBGene00170365 21ur-13473 No description available WB:WBGene00170366 21ur-12156 No description available WB:WBGene00170367 21ur-8698 No description available WB:WBGene00170368 21ur-9309 No description available WB:WBGene00170369 21ur-11290 No description available WB:WBGene00170370 21ur-9086 No description available WB:WBGene00170371 21ur-5971 No description available WB:WBGene00170372 21ur-12691 No description available WB:WBGene00170373 21ur-5613 No description available WB:WBGene00170374 21ur-15443 No description available WB:WBGene00170375 21ur-5463 No description available WB:WBGene00170376 21ur-13818 No description available WB:WBGene00170377 21ur-8261 No description available WB:WBGene00170378 21ur-7622 No description available WB:WBGene00170379 21ur-12507 No description available WB:WBGene00170380 21ur-14378 No description available WB:WBGene00170381 21ur-12072 No description available WB:WBGene00170382 21ur-7680 No description available WB:WBGene00170383 21ur-8488 No description available WB:WBGene00170384 21ur-11635 No description available WB:WBGene00170385 21ur-10450 No description available WB:WBGene00170386 21ur-7103 No description available WB:WBGene00170387 21ur-9751 No description available WB:WBGene00170388 21ur-13503 No description available WB:WBGene00170389 21ur-9029 No description available WB:WBGene00170390 21ur-15046 No description available WB:WBGene00170391 21ur-12798 No description available WB:WBGene00170392 21ur-8495 No description available WB:WBGene00170393 21ur-5700 No description available WB:WBGene00170394 21ur-7467 No description available WB:WBGene00170395 21ur-6834 No description available WB:WBGene00170396 21ur-11217 No description available WB:WBGene00170397 21ur-15259 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00170398 21ur-6027 Is affected by set-2 based on RNA-seq studies. WB:WBGene00170399 21ur-7981 No description available WB:WBGene00170400 21ur-13355 No description available WB:WBGene00170401 21ur-15060 Enriched in neurons based on RNA-seq studies. WB:WBGene00170402 21ur-12319 No description available WB:WBGene00170403 21ur-5597 No description available WB:WBGene00170404 21ur-7176 No description available WB:WBGene00170405 21ur-7525 No description available WB:WBGene00170406 21ur-9049 No description available WB:WBGene00170407 21ur-11210 No description available WB:WBGene00170408 21ur-12822 No description available WB:WBGene00170409 21ur-11814 No description available WB:WBGene00170410 21ur-14259 No description available WB:WBGene00170411 21ur-5545 No description available WB:WBGene00170412 21ur-6614 No description available WB:WBGene00170413 21ur-7477 No description available WB:WBGene00170414 21ur-6070 No description available WB:WBGene00170415 21ur-6583 No description available WB:WBGene00170416 21ur-15319 Is affected by set-2 based on RNA-seq studies. WB:WBGene00170417 21ur-6497 No description available WB:WBGene00170418 21ur-10958 No description available WB:WBGene00170419 21ur-6982 No description available WB:WBGene00170420 21ur-5591 No description available WB:WBGene00170421 21ur-6042 No description available WB:WBGene00170422 21ur-12403 No description available WB:WBGene00170423 21ur-13906 No description available WB:WBGene00170424 21ur-15065 No description available WB:WBGene00170425 21ur-6651 No description available WB:WBGene00170426 21ur-12969 No description available WB:WBGene00170427 21ur-13737 No description available WB:WBGene00170428 21ur-7645 Enriched in neurons based on RNA-seq studies. WB:WBGene00170429 21ur-5943 Enriched in neurons based on RNA-seq studies. WB:WBGene00170430 21ur-7497 No description available WB:WBGene00170431 21ur-13516 No description available WB:WBGene00170432 21ur-15031 No description available WB:WBGene00170433 21ur-12730 Enriched in neurons based on RNA-seq studies. WB:WBGene00170434 21ur-13110 No description available WB:WBGene00170435 21ur-12741 No description available WB:WBGene00170436 21ur-14298 No description available WB:WBGene00170437 21ur-10010 No description available WB:WBGene00170438 21ur-7356 No description available WB:WBGene00170439 21ur-7629 No description available WB:WBGene00170440 21ur-10281 No description available WB:WBGene00170441 21ur-10949 No description available WB:WBGene00170442 21ur-10968 No description available WB:WBGene00170443 21ur-7742 No description available WB:WBGene00170444 21ur-9223 No description available WB:WBGene00170445 21ur-7937 No description available WB:WBGene00170446 21ur-12120 No description available WB:WBGene00170447 21ur-10218 Enriched in neurons based on RNA-seq studies. WB:WBGene00170448 21ur-8535 No description available WB:WBGene00170449 21ur-13421 No description available WB:WBGene00170450 21ur-6279 No description available WB:WBGene00170451 21ur-9758 No description available WB:WBGene00170452 21ur-10676 No description available WB:WBGene00170453 21ur-5555 No description available WB:WBGene00170454 21ur-14371 No description available WB:WBGene00170455 21ur-15509 No description available WB:WBGene00170456 21ur-6011 No description available WB:WBGene00170457 21ur-9094 No description available WB:WBGene00170458 21ur-12676 No description available WB:WBGene00170459 21ur-14827 No description available WB:WBGene00170460 21ur-10114 No description available WB:WBGene00170461 21ur-7926 No description available WB:WBGene00170462 21ur-11614 No description available WB:WBGene00170463 21ur-10317 No description available WB:WBGene00170464 21ur-5984 No description available WB:WBGene00170465 21ur-14639 No description available WB:WBGene00170466 21ur-9144 No description available WB:WBGene00170467 21ur-12949 No description available WB:WBGene00170468 21ur-11398 No description available WB:WBGene00170469 21ur-12734 No description available WB:WBGene00170470 21ur-12909 No description available WB:WBGene00170471 21ur-15118 No description available WB:WBGene00170472 21ur-13605 No description available WB:WBGene00170473 21ur-5750 No description available WB:WBGene00170474 21ur-9873 No description available WB:WBGene00170475 21ur-5489 No description available WB:WBGene00170476 21ur-11633 No description available WB:WBGene00170477 21ur-14413 No description available WB:WBGene00170478 21ur-11051 No description available WB:WBGene00170479 21ur-7004 No description available WB:WBGene00170480 21ur-10919 No description available WB:WBGene00170481 21ur-10075 No description available WB:WBGene00170482 21ur-9417 No description available WB:WBGene00170483 21ur-14843 No description available WB:WBGene00170484 21ur-8923 No description available WB:WBGene00170485 21ur-10918 No description available WB:WBGene00170486 21ur-11708 No description available WB:WBGene00170487 21ur-15283 No description available WB:WBGene00170488 21ur-6302 No description available WB:WBGene00170489 21ur-13746 No description available WB:WBGene00170490 21ur-5705 No description available WB:WBGene00170491 21ur-9911 No description available WB:WBGene00170492 21ur-6578 No description available WB:WBGene00170493 21ur-10348 No description available WB:WBGene00170494 21ur-12847 No description available WB:WBGene00170495 21ur-12903 No description available WB:WBGene00170496 21ur-10488 No description available WB:WBGene00170497 21ur-12564 No description available WB:WBGene00170498 21ur-12875 No description available WB:WBGene00170499 21ur-10971 No description available WB:WBGene00170500 21ur-12634 No description available WB:WBGene00170501 21ur-7090 No description available WB:WBGene00170502 21ur-8266 No description available WB:WBGene00170503 21ur-9664 No description available WB:WBGene00170504 21ur-10146 No description available WB:WBGene00170505 21ur-12058 No description available WB:WBGene00170506 21ur-15222 No description available WB:WBGene00170507 21ur-12584 No description available WB:WBGene00170508 21ur-13416 No description available WB:WBGene00170509 21ur-9328 No description available WB:WBGene00170510 21ur-12283 No description available WB:WBGene00170511 21ur-12620 No description available WB:WBGene00170512 21ur-7115 No description available WB:WBGene00170513 21ur-12444 No description available WB:WBGene00170514 21ur-14275 No description available WB:WBGene00170515 21ur-13252 No description available WB:WBGene00170516 21ur-9770 No description available WB:WBGene00170517 21ur-7816 No description available WB:WBGene00170518 21ur-6218 No description available WB:WBGene00170519 21ur-6280 No description available WB:WBGene00170520 21ur-12836 No description available WB:WBGene00170521 21ur-9523 Is affected by olrn-1 based on RNA-seq studies. WB:WBGene00170522 21ur-11772 No description available WB:WBGene00170523 21ur-15665 No description available WB:WBGene00170524 21ur-10207 No description available WB:WBGene00170525 21ur-11299 No description available WB:WBGene00170526 21ur-14149 No description available WB:WBGene00170527 21ur-8709 No description available WB:WBGene00170528 21ur-13535 No description available WB:WBGene00170529 21ur-6394 No description available WB:WBGene00170530 21ur-9728 No description available WB:WBGene00170531 21ur-15174 No description available WB:WBGene00170532 21ur-11554 No description available WB:WBGene00170533 21ur-8778 No description available WB:WBGene00170534 21ur-12776 No description available WB:WBGene00170535 21ur-6348 Enriched in neurons based on RNA-seq studies. WB:WBGene00170536 21ur-10390 No description available WB:WBGene00170537 21ur-7633 No description available WB:WBGene00170538 21ur-15011 No description available WB:WBGene00170539 21ur-14699 Is affected by hmg-3 and hlh-26 based on RNA-seq studies. WB:WBGene00170540 21ur-10547 No description available WB:WBGene00170541 21ur-6873 No description available WB:WBGene00170542 21ur-10429 No description available WB:WBGene00170543 21ur-10309 No description available WB:WBGene00170544 21ur-11792 No description available WB:WBGene00170545 21ur-6475 No description available WB:WBGene00170546 21ur-6169 No description available WB:WBGene00170547 21ur-7020 No description available WB:WBGene00170548 21ur-7905 No description available WB:WBGene00170549 21ur-12555 No description available WB:WBGene00170550 21ur-14339 No description available WB:WBGene00170551 21ur-12629 No description available WB:WBGene00170552 21ur-14169 No description available WB:WBGene00170553 21ur-7431 No description available WB:WBGene00170554 21ur-12200 No description available WB:WBGene00170555 21ur-14895 No description available WB:WBGene00170556 21ur-6264 No description available WB:WBGene00170557 21ur-9443 No description available WB:WBGene00170558 21ur-14063 No description available WB:WBGene00170559 21ur-9478 No description available WB:WBGene00170560 21ur-12308 No description available WB:WBGene00170561 21ur-14543 No description available WB:WBGene00170562 21ur-14739 Enriched in neurons based on RNA-seq studies. WB:WBGene00170563 21ur-6666 No description available WB:WBGene00170564 21ur-9588 No description available WB:WBGene00170565 21ur-8960 No description available WB:WBGene00170566 21ur-6763 No description available WB:WBGene00170567 21ur-5617 No description available WB:WBGene00170568 21ur-11351 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00170569 21ur-14584 No description available WB:WBGene00170570 21ur-14670 Is affected by ins-11 and set-2 based on RNA-seq studies. Is affected by bisphenol A based on RNA-seq studies. WB:WBGene00170571 21ur-11999 No description available WB:WBGene00170572 21ur-6097 No description available WB:WBGene00170573 21ur-10397 No description available WB:WBGene00170574 21ur-8789 Is affected by ints-2 based on RNA-seq studies. WB:WBGene00170575 21ur-10564 No description available WB:WBGene00170576 21ur-11670 No description available WB:WBGene00170577 21ur-6856 No description available WB:WBGene00170578 21ur-11917 No description available WB:WBGene00170579 21ur-11984 No description available WB:WBGene00170580 21ur-6311 No description available WB:WBGene00170581 21ur-15697 No description available WB:WBGene00170582 21ur-8451 No description available WB:WBGene00170583 21ur-13349 No description available WB:WBGene00170584 21ur-8121 No description available WB:WBGene00170585 21ur-7365 No description available WB:WBGene00170586 21ur-13461 No description available WB:WBGene00170587 21ur-13837 No description available WB:WBGene00170588 21ur-10695 Enriched in neurons based on RNA-seq studies. WB:WBGene00170589 21ur-14004 No description available WB:WBGene00170590 21ur-5780 No description available WB:WBGene00170591 21ur-9833 No description available WB:WBGene00170592 21ur-6896 No description available WB:WBGene00170593 21ur-11598 No description available WB:WBGene00170594 21ur-6747 No description available WB:WBGene00170595 21ur-11167 No description available WB:WBGene00170596 21ur-10080 No description available WB:WBGene00170597 21ur-7442 No description available WB:WBGene00170598 21ur-7765 No description available WB:WBGene00170599 21ur-14140 No description available WB:WBGene00170600 21ur-11360 Enriched in neurons based on RNA-seq studies. WB:WBGene00170601 21ur-8187 No description available WB:WBGene00170602 21ur-12141 No description available WB:WBGene00170603 21ur-7447 No description available WB:WBGene00170604 21ur-10243 No description available WB:WBGene00170605 21ur-10589 No description available WB:WBGene00170606 21ur-8808 No description available WB:WBGene00170607 21ur-5757 No description available WB:WBGene00170608 21ur-8522 No description available WB:WBGene00170609 21ur-8543 Is affected by lem-2; emr-1; and nfki-1 based on RNA-seq studies. WB:WBGene00170610 21ur-10304 No description available WB:WBGene00170611 21ur-10459 No description available WB:WBGene00170612 21ur-13724 No description available WB:WBGene00170613 21ur-14574 No description available WB:WBGene00170614 21ur-9804 No description available WB:WBGene00170615 21ur-15001 No description available WB:WBGene00170616 21ur-14495 No description available WB:WBGene00170617 21ur-14345 No description available WB:WBGene00170618 21ur-15502 No description available WB:WBGene00170619 21ur-9389 No description available WB:WBGene00170620 21ur-15433 No description available WB:WBGene00170621 21ur-6222 No description available WB:WBGene00170622 21ur-11666 No description available WB:WBGene00170623 21ur-6144 No description available WB:WBGene00170624 21ur-8149 No description available WB:WBGene00170625 21ur-15107 No description available WB:WBGene00170626 21ur-8285 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00170627 21ur-6085 No description available WB:WBGene00170628 21ur-12364 Is affected by hmg-4 and spt-16 based on RNA-seq studies. WB:WBGene00170629 21ur-7279 No description available WB:WBGene00170630 21ur-13026 No description available WB:WBGene00170631 21ur-13742 No description available WB:WBGene00170632 21ur-6918 No description available WB:WBGene00170633 21ur-10208 No description available WB:WBGene00170634 21ur-5926 No description available WB:WBGene00170635 21ur-5699 No description available WB:WBGene00170636 21ur-7698 No description available WB:WBGene00170637 21ur-9635 No description available WB:WBGene00170638 21ur-15008 No description available WB:WBGene00170639 21ur-7640 No description available WB:WBGene00170640 21ur-15054 No description available WB:WBGene00170641 21ur-6367 No description available WB:WBGene00170642 21ur-6755 No description available WB:WBGene00170643 21ur-8361 No description available WB:WBGene00170644 21ur-9321 No description available WB:WBGene00170645 21ur-14160 No description available WB:WBGene00170646 21ur-10932 No description available WB:WBGene00170647 21ur-12208 No description available WB:WBGene00170648 21ur-10138 No description available WB:WBGene00170649 21ur-14868 No description available WB:WBGene00170650 21ur-8185 No description available WB:WBGene00170651 21ur-5761 No description available WB:WBGene00170652 21ur-15140 Enriched in neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00170653 21ur-7210 No description available WB:WBGene00170654 21ur-14997 No description available WB:WBGene00170655 21ur-7544 No description available WB:WBGene00170656 21ur-9219 No description available WB:WBGene00170657 21ur-5833 No description available WB:WBGene00170658 21ur-10998 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00170659 21ur-12980 No description available WB:WBGene00170660 21ur-8646 No description available WB:WBGene00170661 21ur-8425 No description available WB:WBGene00170662 21ur-8747 No description available WB:WBGene00170663 21ur-10592 No description available WB:WBGene00170664 21ur-12288 No description available WB:WBGene00170665 21ur-12486 No description available WB:WBGene00170666 21ur-6771 Enriched in neurons based on RNA-seq studies. WB:WBGene00170667 21ur-11976 No description available WB:WBGene00170668 21ur-7246 No description available WB:WBGene00170669 21ur-9012 No description available WB:WBGene00170670 21ur-12135 Enriched in neurons based on RNA-seq studies. WB:WBGene00170671 21ur-12887 No description available WB:WBGene00170672 21ur-6781 No description available WB:WBGene00170673 21ur-15418 No description available WB:WBGene00170674 21ur-14557 No description available WB:WBGene00170675 21ur-11184 No description available WB:WBGene00170676 21ur-12374 No description available WB:WBGene00170677 21ur-11452 No description available WB:WBGene00170678 21ur-12976 No description available WB:WBGene00170679 21ur-13469 Enriched in neurons based on RNA-seq studies. WB:WBGene00170680 21ur-13753 No description available WB:WBGene00170681 21ur-6889 No description available WB:WBGene00170682 21ur-8097 No description available WB:WBGene00170683 21ur-8599 No description available WB:WBGene00170684 21ur-9452 Enriched in neurons based on RNA-seq studies. Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00170685 21ur-6528 No description available WB:WBGene00170686 21ur-7203 No description available WB:WBGene00170687 21ur-6547 No description available WB:WBGene00170688 21ur-8214 No description available WB:WBGene00170689 21ur-10238 No description available WB:WBGene00170690 21ur-12259 Is affected by eat-2 based on microarray studies. WB:WBGene00170691 21ur-7540 No description available WB:WBGene00170692 21ur-12125 No description available WB:WBGene00170693 21ur-6589 No description available WB:WBGene00170694 21ur-13217 No description available WB:WBGene00170695 21ur-12856 No description available WB:WBGene00170697 21ur-13013 No description available WB:WBGene00170698 21ur-13226 No description available WB:WBGene00170699 21ur-14405 No description available WB:WBGene00170700 21ur-14008 No description available WB:WBGene00170701 21ur-6224 No description available WB:WBGene00170702 21ur-12342 No description available WB:WBGene00170703 21ur-7750 No description available WB:WBGene00170704 21ur-14919 No description available WB:WBGene00170705 21ur-14041 No description available WB:WBGene00170706 21ur-10717 No description available WB:WBGene00170707 21ur-6619 No description available WB:WBGene00170708 21ur-10496 No description available WB:WBGene00170709 21ur-7821 No description available WB:WBGene00170710 21ur-11529 No description available WB:WBGene00170711 21ur-6753 No description available WB:WBGene00170712 21ur-7180 No description available WB:WBGene00170713 21ur-7300 No description available WB:WBGene00170714 21ur-10721 No description available WB:WBGene00170715 21ur-12369 No description available WB:WBGene00170716 21ur-6167 No description available WB:WBGene00170717 21ur-6138 No description available WB:WBGene00170718 21ur-6797 No description available WB:WBGene00170719 21ur-12478 No description available WB:WBGene00170720 21ur-15554 No description available WB:WBGene00170721 21ur-9579 No description available WB:WBGene00170722 21ur-13444 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00170723 21ur-7475 No description available WB:WBGene00170724 21ur-9439 No description available WB:WBGene00170725 21ur-8702 Enriched in neurons based on RNA-seq studies. WB:WBGene00170726 21ur-14057 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00170727 21ur-6784 No description available WB:WBGene00170728 21ur-12410 No description available WB:WBGene00170729 21ur-7503 No description available WB:WBGene00170730 21ur-10742 No description available WB:WBGene00170731 21ur-9875 No description available WB:WBGene00170732 21ur-12537 No description available WB:WBGene00170733 21ur-12899 No description available WB:WBGene00170734 21ur-8440 No description available WB:WBGene00170735 21ur-10794 No description available WB:WBGene00170736 21ur-5821 No description available WB:WBGene00170737 21ur-6540 No description available WB:WBGene00170738 21ur-9732 No description available WB:WBGene00170739 21ur-9699 No description available WB:WBGene00170740 21ur-13092 No description available WB:WBGene00170741 21ur-15155 No description available WB:WBGene00170742 21ur-12099 No description available WB:WBGene00170743 21ur-13772 Enriched in neurons based on RNA-seq studies. WB:WBGene00170744 21ur-12100 No description available WB:WBGene00170745 21ur-8511 No description available WB:WBGene00170746 21ur-12086 No description available WB:WBGene00170747 21ur-13441 No description available WB:WBGene00170748 21ur-6402 No description available WB:WBGene00170749 21ur-15654 No description available WB:WBGene00170750 21ur-14720 No description available WB:WBGene00170751 21ur-14219 No description available WB:WBGene00170752 21ur-10771 No description available WB:WBGene00170753 21ur-14773 No description available WB:WBGene00170754 21ur-6948 No description available WB:WBGene00170755 21ur-7636 No description available WB:WBGene00170756 21ur-9050 No description available WB:WBGene00170757 21ur-6769 No description available WB:WBGene00170758 21ur-8416 No description available WB:WBGene00170759 21ur-7662 No description available WB:WBGene00170760 21ur-9556 No description available WB:WBGene00170761 21ur-12450 No description available WB:WBGene00170762 21ur-8749 No description available WB:WBGene00170763 21ur-7395 No description available WB:WBGene00170764 21ur-7486 No description available WB:WBGene00170765 21ur-5806 No description available WB:WBGene00170766 21ur-6326 No description available WB:WBGene00170767 21ur-14732 No description available WB:WBGene00170768 21ur-8716 No description available WB:WBGene00170769 21ur-12164 No description available WB:WBGene00170770 21ur-14342 No description available WB:WBGene00170771 21ur-6836 No description available WB:WBGene00170772 21ur-10250 No description available WB:WBGene00170773 21ur-15489 No description available WB:WBGene00170774 21ur-12196 No description available WB:WBGene00170775 21ur-5532 No description available WB:WBGene00170776 21ur-8445 No description available WB:WBGene00170777 21ur-11325 No description available WB:WBGene00170778 21ur-14300 No description available WB:WBGene00170779 21ur-12131 No description available WB:WBGene00170780 21ur-9830 No description available WB:WBGene00170781 21ur-11485 No description available WB:WBGene00170782 21ur-12578 No description available WB:WBGene00170783 21ur-13037 No description available WB:WBGene00170784 21ur-9614 No description available WB:WBGene00170785 21ur-8291 No description available WB:WBGene00170786 21ur-11694 No description available WB:WBGene00170787 21ur-10804 No description available WB:WBGene00170788 21ur-12225 No description available WB:WBGene00170789 21ur-13232 No description available WB:WBGene00170790 21ur-9242 No description available WB:WBGene00170791 21ur-6787 No description available WB:WBGene00170792 21ur-13865 No description available WB:WBGene00170793 21ur-13069 No description available WB:WBGene00170794 21ur-7714 No description available WB:WBGene00170795 21ur-6717 No description available WB:WBGene00170796 21ur-14788 Is affected by daf-2 based on microarray studies. WB:WBGene00170797 21ur-8228 No description available WB:WBGene00170798 21ur-11331 No description available WB:WBGene00170799 21ur-13725 No description available WB:WBGene00170800 21ur-10878 No description available WB:WBGene00170801 21ur-8738 No description available WB:WBGene00170802 21ur-7067 Enriched in neurons based on RNA-seq studies. WB:WBGene00170803 21ur-13060 No description available WB:WBGene00170804 21ur-10443 No description available WB:WBGene00170805 21ur-10116 No description available WB:WBGene00170806 21ur-13327 Is affected by Tamoxifen based on RNA-seq studies. WB:WBGene00170807 21ur-6612 No description available WB:WBGene00170808 21ur-12658 Enriched in neurons based on RNA-seq studies. WB:WBGene00170809 21ur-14330 Is affected by blmp-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00170810 21ur-11366 No description available WB:WBGene00170811 21ur-8147 Enriched in neurons based on RNA-seq studies. WB:WBGene00170812 21ur-13307 Enriched in neurons based on RNA-seq studies. WB:WBGene00170813 21ur-6233 Enriched in neurons based on RNA-seq studies. WB:WBGene00170814 21ur-6512 No description available WB:WBGene00170815 21ur-12939 No description available WB:WBGene00170816 21ur-8430 No description available WB:WBGene00170817 21ur-10295 No description available WB:WBGene00170818 21ur-7919 No description available WB:WBGene00170819 21ur-12297 No description available WB:WBGene00170820 21ur-13436 No description available WB:WBGene00170821 21ur-6065 Enriched in neurons based on RNA-seq studies. WB:WBGene00170822 21ur-15534 No description available WB:WBGene00170823 21ur-7165 No description available WB:WBGene00170824 21ur-10444 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00170825 21ur-10822 Is affected by lem-2; emr-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00170826 21ur-15598 No description available WB:WBGene00170827 21ur-8135 No description available WB:WBGene00170828 21ur-14566 No description available WB:WBGene00170829 21ur-5813 No description available WB:WBGene00170830 21ur-14549 No description available WB:WBGene00170831 21ur-7745 No description available WB:WBGene00170832 21ur-9957 No description available WB:WBGene00170833 21ur-5817 No description available WB:WBGene00170834 21ur-6482 No description available WB:WBGene00170835 21ur-11585 No description available WB:WBGene00170836 21ur-14888 No description available WB:WBGene00170837 21ur-6379 Enriched in neurons based on RNA-seq studies. WB:WBGene00170838 21ur-8497 No description available WB:WBGene00170839 21ur-13323 No description available WB:WBGene00170840 21ur-13332 No description available WB:WBGene00170841 21ur-14604 No description available WB:WBGene00170842 21ur-15229 Enriched in neurons based on RNA-seq studies. WB:WBGene00170843 21ur-12581 No description available WB:WBGene00170844 21ur-8624 No description available WB:WBGene00170845 21ur-10733 No description available WB:WBGene00170846 21ur-12729 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00170847 21ur-13050 No description available WB:WBGene00170848 21ur-12179 No description available WB:WBGene00170849 21ur-14962 No description available WB:WBGene00170850 21ur-9931 No description available WB:WBGene00170851 21ur-6844 No description available WB:WBGene00170852 21ur-7327 No description available WB:WBGene00170853 21ur-5495 No description available WB:WBGene00170854 21ur-8731 No description available WB:WBGene00170855 21ur-13917 No description available WB:WBGene00170856 21ur-9164 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00170857 21ur-6329 No description available WB:WBGene00170858 21ur-14395 No description available WB:WBGene00170859 21ur-7679 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00170860 21ur-10466 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00170861 21ur-13560 No description available WB:WBGene00170862 21ur-15095 Is affected by daf-2; ints-5; and set-2 based on microarray and RNA-seq studies. WB:WBGene00170863 21ur-11828 No description available WB:WBGene00170864 21ur-10708 No description available WB:WBGene00170865 21ur-6900 No description available WB:WBGene00170866 21ur-5490 No description available WB:WBGene00170867 21ur-15341 No description available WB:WBGene00170868 21ur-6429 No description available WB:WBGene00170869 21ur-15233 No description available WB:WBGene00170870 21ur-13282 No description available WB:WBGene00170871 21ur-14978 No description available WB:WBGene00170872 21ur-10399 No description available WB:WBGene00170873 21ur-15616 No description available WB:WBGene00170874 21ur-13771 No description available WB:WBGene00170875 21ur-5480 No description available WB:WBGene00170876 21ur-13153 No description available WB:WBGene00170877 21ur-7469 No description available WB:WBGene00170878 21ur-6266 Enriched in neurons based on RNA-seq studies. WB:WBGene00170879 21ur-6131 No description available WB:WBGene00170880 21ur-15585 No description available WB:WBGene00170881 21ur-7653 No description available WB:WBGene00170882 21ur-10841 No description available WB:WBGene00170883 21ur-12321 No description available WB:WBGene00170884 21ur-14833 Is affected by rnp-6 based on RNA-seq studies. WB:WBGene00170885 21ur-11943 No description available WB:WBGene00170886 21ur-6149 No description available WB:WBGene00170887 21ur-15482 No description available WB:WBGene00170888 21ur-14373 No description available WB:WBGene00170889 21ur-12068 No description available WB:WBGene00170890 21ur-13830 Enriched in neurons based on RNA-seq studies. WB:WBGene00170891 21ur-7495 No description available WB:WBGene00170892 21ur-14587 No description available WB:WBGene00170893 21ur-7911 No description available WB:WBGene00170894 21ur-10837 No description available WB:WBGene00170895 21ur-7986 No description available WB:WBGene00170896 21ur-12840 No description available WB:WBGene00170897 21ur-9821 No description available WB:WBGene00170898 21ur-6430 No description available WB:WBGene00170899 21ur-10984 No description available WB:WBGene00170900 21ur-11408 No description available WB:WBGene00170901 21ur-11056 No description available WB:WBGene00170902 21ur-8588 No description available WB:WBGene00170903 21ur-5665 No description available WB:WBGene00170904 21ur-8796 No description available WB:WBGene00170905 21ur-12900 No description available WB:WBGene00170906 21ur-13395 No description available WB:WBGene00170907 21ur-14133 No description available WB:WBGene00170908 21ur-10194 No description available WB:WBGene00170909 21ur-14203 No description available WB:WBGene00170910 21ur-12571 Enriched in neurons based on RNA-seq studies. WB:WBGene00170911 21ur-6707 No description available WB:WBGene00170912 21ur-10415 No description available WB:WBGene00170913 21ur-6244 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00170914 21ur-10346 No description available WB:WBGene00170915 21ur-14875 No description available WB:WBGene00170916 21ur-5958 No description available WB:WBGene00170917 21ur-9199 No description available WB:WBGene00170918 21ur-8557 No description available WB:WBGene00170919 21ur-11582 No description available WB:WBGene00170920 21ur-15403 No description available WB:WBGene00170921 21ur-8518 No description available WB:WBGene00170922 21ur-7231 No description available WB:WBGene00170923 21ur-15625 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00170924 21ur-11522 No description available WB:WBGene00170925 21ur-12724 No description available WB:WBGene00170926 21ur-15238 No description available WB:WBGene00170927 21ur-14242 No description available WB:WBGene00170928 21ur-13312 No description available WB:WBGene00170929 21ur-14021 No description available WB:WBGene00170930 21ur-6503 No description available WB:WBGene00170931 21ur-8834 No description available WB:WBGene00170932 21ur-13485 No description available WB:WBGene00170933 21ur-15083 No description available WB:WBGene00170934 21ur-12012 No description available WB:WBGene00170935 21ur-5499 Enriched in neurons based on RNA-seq studies. WB:WBGene00170936 21ur-15216 No description available WB:WBGene00170937 21ur-12767 No description available WB:WBGene00170938 21ur-14212 No description available WB:WBGene00170939 21ur-5687 No description available WB:WBGene00170940 21ur-9941 No description available WB:WBGene00170941 21ur-10087 No description available WB:WBGene00170942 21ur-12618 No description available WB:WBGene00170943 21ur-10720 Enriched in neurons based on RNA-seq studies. WB:WBGene00170944 21ur-11738 No description available WB:WBGene00170945 21ur-14189 No description available WB:WBGene00170946 21ur-9783 No description available WB:WBGene00170947 21ur-10023 Enriched in neurons based on RNA-seq studies. WB:WBGene00170948 21ur-14462 No description available WB:WBGene00170949 21ur-14611 No description available WB:WBGene00170950 21ur-8123 Is affected by set-2 based on RNA-seq studies. WB:WBGene00170951 21ur-8256 No description available WB:WBGene00170952 21ur-6690 No description available WB:WBGene00170953 21ur-15479 No description available WB:WBGene00170954 21ur-14924 No description available WB:WBGene00170955 21ur-8962 No description available WB:WBGene00170956 21ur-10904 No description available WB:WBGene00170957 21ur-13290 No description available WB:WBGene00170958 21ur-9502 No description available WB:WBGene00170959 21ur-9901 Enriched in neurons based on RNA-seq studies. WB:WBGene00170960 21ur-11076 No description available WB:WBGene00170961 21ur-11506 No description available WB:WBGene00170962 21ur-7518 No description available WB:WBGene00170963 21ur-6939 No description available WB:WBGene00170964 21ur-11854 No description available WB:WBGene00170965 21ur-8234 No description available WB:WBGene00170966 21ur-9548 No description available WB:WBGene00170967 21ur-15604 Is affected by eat-2 based on microarray studies. WB:WBGene00170968 21ur-12114 No description available WB:WBGene00170969 21ur-9366 Enriched in neurons based on RNA-seq studies. WB:WBGene00170970 21ur-14448 No description available WB:WBGene00170971 21ur-8682 No description available WB:WBGene00170972 21ur-7607 No description available WB:WBGene00170973 21ur-15395 No description available WB:WBGene00170974 21ur-13969 No description available WB:WBGene00170975 21ur-14741 No description available WB:WBGene00170976 21ur-14369 No description available WB:WBGene00170977 21ur-15284 No description available WB:WBGene00170978 21ur-6455 No description available WB:WBGene00170979 21ur-7960 No description available WB:WBGene00170980 21ur-7956 No description available WB:WBGene00170981 21ur-8140 No description available WB:WBGene00170982 21ur-10863 No description available WB:WBGene00170983 21ur-10679 No description available WB:WBGene00170984 21ur-10632 No description available WB:WBGene00170985 21ur-10151 No description available WB:WBGene00170986 21ur-6990 No description available WB:WBGene00170987 21ur-9370 No description available WB:WBGene00170988 21ur-14206 No description available WB:WBGene00170989 21ur-9073 No description available WB:WBGene00170990 21ur-14155 No description available WB:WBGene00170991 21ur-10753 No description available WB:WBGene00170992 21ur-15248 Is affected by rnp-6 and cpl-1 based on RNA-seq studies. WB:WBGene00170993 21ur-5522 No description available WB:WBGene00170994 21ur-11197 No description available WB:WBGene00170995 21ur-13714 No description available WB:WBGene00170996 21ur-5867 No description available WB:WBGene00170997 21ur-11479 No description available WB:WBGene00170998 21ur-12471 No description available WB:WBGene00170999 21ur-8251 No description available WB:WBGene00171000 21ur-11878 No description available WB:WBGene00171001 21ur-8661 Enriched in neurons based on RNA-seq studies. WB:WBGene00171002 21ur-9918 Is affected by set-2 based on RNA-seq studies. WB:WBGene00171003 21ur-9071 No description available WB:WBGene00171004 21ur-10761 No description available WB:WBGene00171005 21ur-12971 No description available WB:WBGene00171006 21ur-13151 No description available WB:WBGene00171007 21ur-10936 No description available WB:WBGene00171008 21ur-13350 No description available WB:WBGene00171009 21ur-5997 No description available WB:WBGene00171010 21ur-15619 No description available WB:WBGene00171011 21ur-9124 No description available WB:WBGene00171012 21ur-11373 Enriched in neurons based on RNA-seq studies. WB:WBGene00171013 21ur-14237 No description available WB:WBGene00171014 21ur-11152 No description available WB:WBGene00171015 21ur-5855 No description available WB:WBGene00171016 21ur-12118 No description available WB:WBGene00171017 21ur-7862 Enriched in neurons based on RNA-seq studies. WB:WBGene00171018 21ur-9088 No description available WB:WBGene00171019 21ur-12521 No description available WB:WBGene00171020 21ur-7728 No description available WB:WBGene00171021 21ur-5875 No description available WB:WBGene00171022 21ur-6009 No description available WB:WBGene00171023 21ur-13987 No description available WB:WBGene00171024 21ur-14630 No description available WB:WBGene00171025 21ur-7538 No description available WB:WBGene00171026 21ur-6575 No description available WB:WBGene00171027 21ur-7832 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00171028 21ur-13192 No description available WB:WBGene00171029 21ur-15620 No description available WB:WBGene00171030 21ur-15631 No description available WB:WBGene00171031 21ur-8870 No description available WB:WBGene00171032 21ur-12886 No description available WB:WBGene00171033 21ur-11951 No description available WB:WBGene00171034 21ur-5850 No description available WB:WBGene00171035 21ur-11176 No description available WB:WBGene00171036 21ur-11537 Is affected by eat-2 based on microarray studies. WB:WBGene00171037 21ur-14435 No description available WB:WBGene00171038 21ur-9985 No description available WB:WBGene00171039 21ur-15029 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00171040 21ur-15425 No description available WB:WBGene00171041 21ur-12950 No description available WB:WBGene00171042 21ur-9065 No description available WB:WBGene00171043 21ur-11116 No description available WB:WBGene00171044 21ur-12959 No description available WB:WBGene00171045 21ur-13505 No description available WB:WBGene00171046 21ur-15261 Enriched in neurons based on RNA-seq studies. Is affected by several genes including unc-70; lem-2; and emr-1 based on RNA-seq studies. WB:WBGene00171047 21ur-6119 No description available WB:WBGene00171048 21ur-7085 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00171049 21ur-8197 No description available WB:WBGene00171050 21ur-6671 No description available WB:WBGene00171051 21ur-7924 No description available WB:WBGene00171052 21ur-6494 No description available WB:WBGene00171053 21ur-7223 No description available WB:WBGene00171054 21ur-7409 No description available WB:WBGene00171055 21ur-13687 No description available WB:WBGene00171056 21ur-15275 No description available WB:WBGene00171057 21ur-15100 No description available WB:WBGene00171058 21ur-15141 No description available WB:WBGene00171059 21ur-11981 No description available WB:WBGene00171060 21ur-5524 No description available WB:WBGene00171061 21ur-14971 No description available WB:WBGene00171062 21ur-14433 No description available WB:WBGene00171063 21ur-10639 No description available WB:WBGene00171064 21ur-14576 No description available WB:WBGene00171065 21ur-7014 No description available WB:WBGene00171066 21ur-7685 No description available WB:WBGene00171067 21ur-8390 No description available WB:WBGene00171068 21ur-10668 No description available WB:WBGene00171069 21ur-7907 No description available WB:WBGene00171070 21ur-9566 No description available WB:WBGene00171071 21ur-8190 Is affected by cadmium based on RNA-seq studies. WB:WBGene00171072 21ur-13973 Is affected by emr-1 and hmg-3 based on RNA-seq studies. WB:WBGene00171073 21ur-13095 No description available WB:WBGene00171074 21ur-6121 No description available WB:WBGene00171075 21ur-7567 No description available WB:WBGene00171076 21ur-12755 No description available WB:WBGene00171077 21ur-12492 No description available WB:WBGene00171078 21ur-12514 No description available WB:WBGene00171079 21ur-7453 No description available WB:WBGene00171080 21ur-6190 No description available WB:WBGene00171081 21ur-6563 Enriched in neurons based on RNA-seq studies. WB:WBGene00171082 21ur-8986 No description available WB:WBGene00171083 21ur-10922 No description available WB:WBGene00171084 21ur-5772 No description available WB:WBGene00171085 21ur-15440 No description available WB:WBGene00171086 21ur-15170 No description available WB:WBGene00171087 21ur-7340 Enriched in neurons based on RNA-seq studies. WB:WBGene00171088 21ur-7482 No description available WB:WBGene00171089 21ur-8045 No description available WB:WBGene00171090 21ur-12316 No description available WB:WBGene00171091 21ur-12331 No description available WB:WBGene00171092 21ur-7601 No description available WB:WBGene00171093 21ur-13078 No description available WB:WBGene00171094 21ur-6502 Enriched in neurons based on RNA-seq studies. WB:WBGene00171095 21ur-9453 No description available WB:WBGene00171096 21ur-12516 No description available WB:WBGene00171097 21ur-12910 No description available WB:WBGene00171098 21ur-11606 No description available WB:WBGene00171099 21ur-13303 No description available WB:WBGene00171100 21ur-11083 No description available WB:WBGene00171101 21ur-9648 No description available WB:WBGene00171102 21ur-9377 No description available WB:WBGene00171103 21ur-10294 No description available WB:WBGene00171104 21ur-9382 No description available WB:WBGene00171105 21ur-12051 No description available WB:WBGene00171106 21ur-12712 No description available WB:WBGene00171107 21ur-7563 No description available WB:WBGene00171108 21ur-8315 No description available WB:WBGene00171109 21ur-9198 Is affected by eat-2 based on microarray studies. WB:WBGene00171110 21ur-6317 No description available WB:WBGene00171111 21ur-10054 No description available WB:WBGene00171112 21ur-9315 No description available WB:WBGene00171113 21ur-10562 No description available WB:WBGene00171114 21ur-15673 Is affected by set-2 based on RNA-seq studies. WB:WBGene00171115 21ur-8726 No description available WB:WBGene00171116 21ur-7259 No description available WB:WBGene00171117 21ur-11864 Enriched in neurons based on RNA-seq studies. WB:WBGene00171118 21ur-8931 No description available WB:WBGene00171119 21ur-7187 No description available WB:WBGene00171120 21ur-6735 No description available WB:WBGene00171121 21ur-9889 No description available WB:WBGene00171122 21ur-10569 No description available WB:WBGene00171123 21ur-7260 No description available WB:WBGene00171124 21ur-12686 No description available WB:WBGene00171125 21ur-8380 No description available WB:WBGene00171126 21ur-8053 Enriched in neurons based on RNA-seq studies. WB:WBGene00171127 21ur-12467 No description available WB:WBGene00171128 21ur-7267 No description available WB:WBGene00171129 21ur-5727 No description available WB:WBGene00171130 21ur-12047 No description available WB:WBGene00171131 21ur-14682 No description available WB:WBGene00171132 21ur-11880 No description available WB:WBGene00171133 21ur-6870 No description available WB:WBGene00171134 21ur-8542 No description available WB:WBGene00171135 21ur-9493 No description available WB:WBGene00171136 21ur-12687 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00171137 21ur-13184 No description available WB:WBGene00171138 21ur-13041 No description available WB:WBGene00171139 21ur-14172 No description available WB:WBGene00171140 21ur-11271 No description available WB:WBGene00171141 21ur-11845 Enriched in neurons based on RNA-seq studies. WB:WBGene00171142 21ur-12245 No description available WB:WBGene00171143 21ur-10107 No description available WB:WBGene00171144 21ur-14380 No description available WB:WBGene00171145 21ur-11133 No description available WB:WBGene00171146 21ur-8360 No description available WB:WBGene00171147 21ur-9970 No description available WB:WBGene00171148 21ur-7399 No description available WB:WBGene00171149 21ur-13552 No description available WB:WBGene00171150 21ur-15357 No description available WB:WBGene00171151 21ur-10749 No description available WB:WBGene00171152 21ur-11745 Enriched in neurons based on RNA-seq studies. WB:WBGene00171153 21ur-7852 No description available WB:WBGene00171154 21ur-9263 No description available WB:WBGene00171155 21ur-6923 No description available WB:WBGene00171156 21ur-12422 No description available WB:WBGene00171157 21ur-15071 No description available WB:WBGene00171158 21ur-14794 No description available WB:WBGene00171159 21ur-13999 No description available WB:WBGene00171160 21ur-8689 No description available WB:WBGene00171161 21ur-7798 No description available WB:WBGene00171162 21ur-14987 No description available WB:WBGene00171163 21ur-14791 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00171164 21ur-11245 No description available WB:WBGene00171165 21ur-14469 No description available WB:WBGene00171166 21ur-8612 No description available WB:WBGene00171167 21ur-8308 No description available WB:WBGene00171168 21ur-13526 No description available WB:WBGene00171169 21ur-9870 No description available WB:WBGene00171170 21ur-15331 No description available WB:WBGene00171171 21ur-8242 No description available WB:WBGene00171172 21ur-7093 No description available WB:WBGene00171173 21ur-7939 No description available WB:WBGene00171174 21ur-11007 No description available WB:WBGene00171175 21ur-15152 Enriched in neurons based on RNA-seq studies. WB:WBGene00171176 21ur-8204 No description available WB:WBGene00171177 21ur-13616 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00171178 21ur-5641 No description available WB:WBGene00171179 21ur-13931 No description available WB:WBGene00171180 21ur-8971 No description available WB:WBGene00171181 21ur-12813 No description available WB:WBGene00171182 21ur-11832 No description available WB:WBGene00171183 21ur-14752 Is affected by daf-2 based on microarray studies. WB:WBGene00171184 21ur-9005 No description available WB:WBGene00171185 21ur-11548 No description available WB:WBGene00171186 21ur-7758 No description available WB:WBGene00171187 21ur-6582 No description available WB:WBGene00171188 21ur-10891 No description available WB:WBGene00171189 21ur-12660 No description available WB:WBGene00171190 21ur-6723 No description available WB:WBGene00171191 21ur-9841 No description available WB:WBGene00171192 21ur-7296 No description available WB:WBGene00171193 21ur-9938 No description available WB:WBGene00171194 21ur-13559 No description available WB:WBGene00171195 21ur-6179 No description available WB:WBGene00171196 21ur-11389 No description available WB:WBGene00171197 21ur-8992 No description available WB:WBGene00171198 21ur-15348 No description available WB:WBGene00171199 21ur-12919 No description available WB:WBGene00171200 21ur-7140 No description available WB:WBGene00171201 21ur-14267 No description available WB:WBGene00171202 21ur-7806 No description available WB:WBGene00171203 21ur-10688 No description available WB:WBGene00171204 21ur-8903 No description available WB:WBGene00171205 21ur-9051 Enriched in neurons based on RNA-seq studies. WB:WBGene00171206 21ur-12552 No description available WB:WBGene00171207 21ur-6088 No description available WB:WBGene00171208 21ur-13135 No description available WB:WBGene00171209 21ur-14061 No description available WB:WBGene00171210 21ur-11643 Is affected by several genes including lem-2; emr-1; and hmg-4 based on RNA-seq studies. WB:WBGene00171211 21ur-14191 No description available WB:WBGene00171212 21ur-11740 No description available WB:WBGene00171213 21ur-14984 No description available WB:WBGene00171214 21ur-11027 No description available WB:WBGene00171215 21ur-15165 No description available WB:WBGene00171216 21ur-14038 No description available WB:WBGene00171217 21ur-10889 No description available WB:WBGene00171218 21ur-11574 No description available WB:WBGene00171219 21ur-11992 No description available WB:WBGene00171220 21ur-5476 No description available WB:WBGene00171221 21ur-8114 No description available WB:WBGene00171222 21ur-14810 No description available WB:WBGene00171223 21ur-13789 No description available WB:WBGene00171224 21ur-7155 Enriched in neurons based on RNA-seq studies. WB:WBGene00171225 21ur-8150 No description available WB:WBGene00171226 21ur-11804 No description available WB:WBGene00171227 21ur-14050 No description available WB:WBGene00171228 21ur-14001 No description available WB:WBGene00171229 21ur-15682 No description available WB:WBGene00171230 21ur-7511 No description available WB:WBGene00171231 21ur-10495 No description available WB:WBGene00171232 21ur-13959 No description available WB:WBGene00171233 21ur-7775 No description available WB:WBGene00171234 21ur-13848 Enriched in neurons based on RNA-seq studies. WB:WBGene00171235 21ur-6536 No description available WB:WBGene00171236 21ur-8133 No description available WB:WBGene00171237 21ur-8399 No description available WB:WBGene00171238 21ur-6068 No description available WB:WBGene00171239 21ur-10032 No description available WB:WBGene00171240 21ur-10257 Is affected by vit-5 based on RNA-seq studies. WB:WBGene00171241 21ur-6809 No description available WB:WBGene00171242 21ur-5578 No description available WB:WBGene00171243 21ur-8913 No description available WB:WBGene00171244 21ur-14644 No description available WB:WBGene00171245 21ur-5907 No description available WB:WBGene00171246 21ur-11111 No description available WB:WBGene00171247 21ur-11609 Is affected by eat-2 based on microarray studies. WB:WBGene00171248 21ur-12865 No description available WB:WBGene00171249 21ur-6000 Enriched in neurons based on RNA-seq studies. WB:WBGene00171250 21ur-7693 Enriched in neurons based on RNA-seq studies. WB:WBGene00171251 21ur-12549 No description available WB:WBGene00171252 21ur-8090 No description available WB:WBGene00171253 21ur-8771 Is affected by emr-1; lem-2; and hmg-3 based on RNA-seq studies. WB:WBGene00171254 21ur-11460 No description available WB:WBGene00171255 21ur-6778 Enriched in neurons based on RNA-seq studies. Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00171256 21ur-10335 No description available WB:WBGene00171257 21ur-13825 No description available WB:WBGene00171258 21ur-7059 No description available WB:WBGene00171259 21ur-12809 No description available WB:WBGene00171260 21ur-11337 No description available WB:WBGene00171261 21ur-6282 No description available WB:WBGene00171262 21ur-11719 No description available WB:WBGene00171263 21ur-11579 No description available WB:WBGene00171264 21ur-8765 Enriched in neurons based on RNA-seq studies. WB:WBGene00171265 21ur-10517 No description available WB:WBGene00171266 21ur-8330 No description available WB:WBGene00171267 21ur-6689 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00171268 21ur-12569 No description available WB:WBGene00171269 21ur-6684 No description available WB:WBGene00171270 21ur-12275 No description available WB:WBGene00171271 21ur-11570 No description available WB:WBGene00171272 21ur-14904 No description available WB:WBGene00171273 21ur-8344 No description available WB:WBGene00171274 21ur-5530 No description available WB:WBGene00171275 21ur-9791 No description available WB:WBGene00171276 21ur-11129 No description available WB:WBGene00171277 21ur-9544 No description available WB:WBGene00171278 21ur-8238 No description available WB:WBGene00171279 21ur-10692 No description available WB:WBGene00171280 21ur-14822 No description available WB:WBGene00171281 21ur-5794 No description available WB:WBGene00171282 21ur-15368 No description available WB:WBGene00171283 21ur-15224 Is affected by daf-2 based on microarray studies. WB:WBGene00171284 21ur-13883 No description available WB:WBGene00171285 21ur-13154 No description available WB:WBGene00171286 21ur-15082 No description available WB:WBGene00171287 21ur-12170 No description available WB:WBGene00171288 21ur-8724 No description available WB:WBGene00171289 21ur-15218 No description available WB:WBGene00171290 21ur-7796 No description available WB:WBGene00171291 21ur-15538 No description available WB:WBGene00171292 21ur-7594 No description available WB:WBGene00171293 21ur-6658 No description available WB:WBGene00171294 21ur-11495 No description available WB:WBGene00171295 21ur-12212 No description available WB:WBGene00171296 21ur-10923 No description available WB:WBGene00171297 21ur-14829 No description available WB:WBGene00171298 21ur-15172 No description available WB:WBGene00171299 21ur-14855 No description available WB:WBGene00171300 21ur-15124 No description available WB:WBGene00171301 21ur-11382 No description available WB:WBGene00171302 21ur-11794 No description available WB:WBGene00171303 21ur-11709 No description available WB:WBGene00171304 21ur-6668 No description available WB:WBGene00171305 21ur-14076 No description available WB:WBGene00171306 21ur-6180 No description available WB:WBGene00171307 21ur-6025 No description available WB:WBGene00171308 21ur-5937 No description available WB:WBGene00171309 21ur-6380 No description available WB:WBGene00171310 21ur-6656 No description available WB:WBGene00171311 21ur-11261 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00171312 21ur-6142 No description available WB:WBGene00171313 21ur-7870 No description available WB:WBGene00171314 21ur-6518 No description available WB:WBGene00171315 21ur-14586 No description available WB:WBGene00171316 21ur-10916 No description available WB:WBGene00171317 21ur-10654 No description available WB:WBGene00171318 21ur-15211 No description available WB:WBGene00171319 21ur-8680 No description available WB:WBGene00171320 21ur-11889 No description available WB:WBGene00171321 21ur-6885 No description available WB:WBGene00171322 21ur-15515 No description available WB:WBGene00171323 21ur-8868 Is affected by daf-2 based on microarray studies. WB:WBGene00171324 21ur-14873 No description available WB:WBGene00171325 21ur-14664 Enriched in neurons based on RNA-seq studies. WB:WBGene00171326 21ur-11449 No description available WB:WBGene00171327 21ur-14198 No description available WB:WBGene00171328 21ur-10124 No description available WB:WBGene00171329 21ur-10189 No description available WB:WBGene00171330 21ur-6112 Enriched in neurons based on RNA-seq studies. WB:WBGene00171331 21ur-13586 No description available WB:WBGene00171332 21ur-6731 Enriched in neurons based on RNA-seq studies. WB:WBGene00171333 21ur-5508 No description available WB:WBGene00171334 21ur-10172 No description available WB:WBGene00171335 21ur-14694 No description available WB:WBGene00171336 21ur-9710 No description available WB:WBGene00171337 21ur-13685 No description available WB:WBGene00171338 21ur-11458 No description available WB:WBGene00171339 21ur-9106 No description available WB:WBGene00171340 21ur-11120 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00171341 21ur-15119 No description available WB:WBGene00171342 21ur-6909 No description available WB:WBGene00171343 21ur-13031 No description available WB:WBGene00171344 21ur-11094 No description available WB:WBGene00171345 21ur-11371 No description available WB:WBGene00171346 21ur-15531 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00171347 21ur-12215 No description available WB:WBGene00171348 21ur-13662 No description available WB:WBGene00171349 21ur-9621 No description available WB:WBGene00171350 21ur-7718 No description available WB:WBGene00171351 21ur-12703 No description available WB:WBGene00171352 21ur-15406 No description available WB:WBGene00171353 21ur-6160 No description available WB:WBGene00171354 21ur-5992 No description available WB:WBGene00171355 21ur-10471 Is affected by eat-2 based on microarray studies. WB:WBGene00171356 21ur-13145 No description available WB:WBGene00171357 21ur-13938 No description available WB:WBGene00171358 21ur-8011 No description available WB:WBGene00171359 21ur-8363 No description available WB:WBGene00171360 21ur-15644 No description available WB:WBGene00171361 21ur-11286 No description available WB:WBGene00171362 21ur-14679 No description available WB:WBGene00171363 21ur-6646 No description available WB:WBGene00171364 21ur-6358 No description available WB:WBGene00171365 21ur-5547 No description available WB:WBGene00171366 21ur-8872 No description available WB:WBGene00171367 21ur-8642 No description available WB:WBGene00171368 21ur-11015 No description available WB:WBGene00171369 21ur-11475 No description available WB:WBGene00171370 21ur-9184 No description available WB:WBGene00171371 21ur-14567 No description available WB:WBGene00171372 21ur-12963 No description available WB:WBGene00171373 21ur-8790 No description available WB:WBGene00171374 21ur-12547 No description available WB:WBGene00171375 21ur-13897 No description available WB:WBGene00171376 21ur-8824 Is affected by set-2 based on RNA-seq studies. WB:WBGene00171377 21ur-8947 No description available WB:WBGene00171378 21ur-10097 No description available WB:WBGene00171379 21ur-15445 No description available WB:WBGene00171380 21ur-10248 No description available WB:WBGene00171381 21ur-12641 No description available WB:WBGene00171382 21ur-14319 No description available WB:WBGene00171383 21ur-15186 No description available WB:WBGene00171384 21ur-10378 No description available WB:WBGene00171385 21ur-9131 No description available WB:WBGene00171386 21ur-15344 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00171387 21ur-5739 No description available WB:WBGene00171388 21ur-13476 No description available WB:WBGene00171389 21ur-7039 No description available WB:WBGene00171390 21ur-13966 No description available WB:WBGene00171391 21ur-14820 No description available WB:WBGene00171392 21ur-10321 No description available WB:WBGene00171393 21ur-11668 No description available WB:WBGene00171394 21ur-9292 No description available WB:WBGene00171395 21ur-9916 No description available WB:WBGene00171396 21ur-14320 Enriched in neurons based on RNA-seq studies. WB:WBGene00171397 21ur-14815 No description available WB:WBGene00171398 21ur-10900 No description available WB:WBGene00171399 21ur-7371 No description available WB:WBGene00171400 21ur-7932 No description available WB:WBGene00171401 21ur-9030 No description available WB:WBGene00171402 21ur-12362 Is affected by eat-2 based on microarray studies. WB:WBGene00171403 21ur-10906 No description available WB:WBGene00171404 21ur-15695 No description available WB:WBGene00171405 21ur-13368 No description available WB:WBGene00171406 21ur-13475 No description available WB:WBGene00171407 21ur-15546 No description available WB:WBGene00171408 21ur-15383 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00171409 21ur-10179 No description available WB:WBGene00171410 21ur-7819 No description available WB:WBGene00171411 21ur-6393 No description available WB:WBGene00171412 21ur-8397 No description available WB:WBGene00171413 21ur-6630 No description available WB:WBGene00171414 21ur-8898 No description available WB:WBGene00171415 21ur-9876 No description available WB:WBGene00171416 21ur-9410 No description available WB:WBGene00171417 21ur-13581 No description available WB:WBGene00171418 21ur-5551 No description available WB:WBGene00171419 21ur-10699 No description available WB:WBGene00171420 21ur-10953 No description available WB:WBGene00171421 21ur-15640 No description available WB:WBGene00171422 21ur-5842 No description available WB:WBGene00171423 21ur-6509 No description available WB:WBGene00171424 21ur-8940 No description available WB:WBGene00171425 21ur-14503 No description available WB:WBGene00171426 21ur-14483 No description available WB:WBGene00171427 21ur-11254 No description available WB:WBGene00171428 21ur-7709 No description available WB:WBGene00171429 21ur-11758 No description available WB:WBGene00171430 21ur-13120 Enriched in neurons based on RNA-seq studies. WB:WBGene00171431 21ur-9692 No description available WB:WBGene00171432 21ur-11442 No description available WB:WBGene00171433 21ur-7097 No description available WB:WBGene00171434 21ur-7062 No description available WB:WBGene00171435 21ur-7958 No description available WB:WBGene00171436 21ur-5514 Enriched in neurons based on RNA-seq studies. WB:WBGene00171437 21ur-8063 Enriched in neurons based on RNA-seq studies. WB:WBGene00171438 21ur-7393 No description available WB:WBGene00171439 21ur-5916 No description available WB:WBGene00171440 21ur-8786 No description available WB:WBGene00171441 21ur-12029 No description available WB:WBGene00171442 21ur-12786 No description available WB:WBGene00171443 21ur-5886 No description available WB:WBGene00171444 21ur-8911 No description available WB:WBGene00171445 21ur-9897 No description available WB:WBGene00171446 21ur-13160 Is affected by set-2 based on RNA-seq studies. WB:WBGene00171447 21ur-5671 No description available WB:WBGene00171448 21ur-9042 No description available WB:WBGene00171449 21ur-10648 Is affected by rnp-6 based on RNA-seq studies. WB:WBGene00171450 21ur-14512 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00171451 21ur-13778 No description available WB:WBGene00171452 21ur-13265 No description available WB:WBGene00171453 21ur-7194 No description available WB:WBGene00171454 21ur-6623 No description available WB:WBGene00171455 21ur-14091 No description available WB:WBGene00171456 21ur-7655 No description available WB:WBGene00171457 21ur-9638 No description available WB:WBGene00171458 21ur-13708 No description available WB:WBGene00171459 21ur-15044 No description available WB:WBGene00171460 21ur-5568 No description available WB:WBGene00171461 21ur-12815 Enriched in neurons based on RNA-seq studies. WB:WBGene00171462 21ur-14497 No description available WB:WBGene00171463 21ur-5501 No description available WB:WBGene00171464 21ur-6353 No description available WB:WBGene00171465 21ur-7427 No description available WB:WBGene00171466 21ur-11663 No description available WB:WBGene00171467 21ur-12227 No description available WB:WBGene00171468 21ur-13280 No description available WB:WBGene00171469 21ur-14282 No description available WB:WBGene00171470 21ur-10255 No description available WB:WBGene00171471 21ur-13138 Enriched in neurons based on RNA-seq studies. WB:WBGene00171472 21ur-9486 No description available WB:WBGene00171473 21ur-11034 No description available WB:WBGene00171474 21ur-7070 Is affected by eat-2 based on microarray studies. WB:WBGene00171475 21ur-13494 Is affected by eat-2 based on microarray studies. WB:WBGene00171476 21ur-15463 No description available WB:WBGene00171477 21ur-11268 No description available WB:WBGene00171478 21ur-7969 No description available WB:WBGene00171479 21ur-9213 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00171480 21ur-15019 No description available WB:WBGene00171481 21ur-14329 No description available WB:WBGene00171482 21ur-6738 No description available WB:WBGene00171483 21ur-5680 No description available WB:WBGene00171484 21ur-7984 No description available WB:WBGene00171485 21ur-15266 No description available WB:WBGene00171486 21ur-14490 No description available WB:WBGene00171487 21ur-9624 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00171488 21ur-8866 No description available WB:WBGene00171489 21ur-11205 No description available WB:WBGene00171490 21ur-9357 No description available WB:WBGene00171491 21ur-15334 No description available WB:WBGene00171492 21ur-8322 No description available WB:WBGene00171493 21ur-9032 No description available WB:WBGene00171494 21ur-6155 No description available WB:WBGene00171495 21ur-8950 No description available WB:WBGene00171496 21ur-10893 No description available WB:WBGene00171497 21ur-14713 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00171498 21ur-6881 No description available WB:WBGene00171499 21ur-10605 No description available WB:WBGene00171500 21ur-13297 No description available WB:WBGene00171501 21ur-7433 No description available WB:WBGene00171502 21ur-7802 No description available WB:WBGene00171503 21ur-11046 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00171504 21ur-13780 No description available WB:WBGene00171505 21ur-11653 No description available WB:WBGene00171506 21ur-10806 Enriched in neurons based on RNA-seq studies. WB:WBGene00171507 21ur-15304 No description available WB:WBGene00171508 21ur-10566 No description available WB:WBGene00171509 21ur-13000 No description available WB:WBGene00171510 21ur-8213 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00171511 21ur-13575 No description available WB:WBGene00171512 21ur-15567 No description available WB:WBGene00171513 21ur-9393 No description available WB:WBGene00171514 21ur-11353 No description available WB:WBGene00171515 21ur-12974 No description available WB:WBGene00171516 21ur-11348 No description available WB:WBGene00171517 21ur-6718 No description available WB:WBGene00171518 21ur-8244 No description available WB:WBGene00171519 21ur-12590 No description available WB:WBGene00171520 21ur-5734 No description available WB:WBGene00171521 21ur-15281 No description available WB:WBGene00171522 21ur-13718 No description available WB:WBGene00171523 21ur-7299 No description available WB:WBGene00171524 21ur-14756 No description available WB:WBGene00171525 21ur-11893 No description available WB:WBGene00171526 21ur-7583 Enriched in neurons based on RNA-seq studies. WB:WBGene00171527 21ur-9687 No description available WB:WBGene00171528 21ur-7414 Enriched in neurons based on RNA-seq studies. WB:WBGene00171529 21ur-13692 No description available WB:WBGene00171530 21ur-9282 No description available WB:WBGene00171531 21ur-8891 No description available WB:WBGene00171532 21ur-9893 No description available WB:WBGene00171533 21ur-8038 No description available WB:WBGene00171534 21ur-11004 No description available WB:WBGene00171535 21ur-6189 No description available WB:WBGene00171536 21ur-6408 No description available WB:WBGene00171537 21ur-8178 No description available WB:WBGene00171538 21ur-14866 No description available WB:WBGene00171539 21ur-14100 No description available WB:WBGene00171540 21ur-13097 No description available WB:WBGene00171541 21ur-5655 Is affected by semo-1 based on RNA-seq studies. WB:WBGene00171542 21ur-11065 No description available WB:WBGene00171543 21ur-14225 No description available WB:WBGene00171544 21ur-12424 Enriched in neurons based on RNA-seq studies. WB:WBGene00171545 21ur-6867 No description available WB:WBGene00171546 21ur-8761 No description available WB:WBGene00171547 21ur-13272 No description available WB:WBGene00171548 21ur-12281 No description available WB:WBGene00171549 21ur-10611 No description available WB:WBGene00171550 21ur-7827 No description available WB:WBGene00171551 21ur-7997 No description available WB:WBGene00171552 21ur-9060 No description available WB:WBGene00171553 21ur-8041 No description available WB:WBGene00171554 21ur-13857 No description available WB:WBGene00171555 21ur-7123 No description available WB:WBGene00171556 21ur-10946 No description available WB:WBGene00171557 21ur-12849 No description available WB:WBGene00171558 21ur-6524 No description available WB:WBGene00171559 21ur-6898 No description available WB:WBGene00171560 21ur-12036 No description available WB:WBGene00171561 21ur-8593 No description available WB:WBGene00171562 21ur-11897 Is affected by rnp-6 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies. WB:WBGene00171563 21ur-6286 No description available WB:WBGene00171564 21ur-6711 No description available WB:WBGene00171565 21ur-14043 Enriched in neurons based on RNA-seq studies. WB:WBGene00171566 21ur-12452 No description available WB:WBGene00171567 21ur-8396 No description available WB:WBGene00171568 21ur-9650 Is affected by set-2 based on RNA-seq studies. WB:WBGene00171569 21ur-10988 No description available WB:WBGene00171570 21ur-5741 No description available WB:WBGene00171571 21ur-9762 No description available WB:WBGene00171572 21ur-8183 No description available WB:WBGene00171573 21ur-14623 No description available WB:WBGene00171574 21ur-8354 No description available WB:WBGene00171575 21ur-10136 No description available WB:WBGene00171576 21ur-10392 Is affected by rrf-3 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00171577 21ur-15370 No description available WB:WBGene00171578 21ur-14761 No description available WB:WBGene00171579 21ur-15431 No description available WB:WBGene00171580 21ur-7292 No description available WB:WBGene00171581 21ur-14945 Is affected by daf-2; eat-2; and cpl-1 based on microarray and RNA-seq studies. Is affected by Tamoxifen based on RNA-seq studies. WB:WBGene00171582 21ur-13240 No description available WB:WBGene00171583 21ur-14598 No description available WB:WBGene00171584 21ur-9495 No description available WB:WBGene00171585 21ur-15002 No description available WB:WBGene00171586 21ur-13245 No description available WB:WBGene00171587 21ur-7615 Enriched in neurons based on RNA-seq studies. WB:WBGene00171588 21ur-7696 No description available WB:WBGene00171589 21ur-13996 No description available WB:WBGene00171590 21ur-9326 No description available WB:WBGene00171591 21ur-10544 No description available WB:WBGene00171592 21ur-6250 No description available WB:WBGene00171593 21ur-12206 No description available WB:WBGene00171594 21ur-13533 No description available WB:WBGene00171595 21ur-12760 No description available WB:WBGene00171596 21ur-15518 No description available WB:WBGene00171597 21ur-8268 No description available WB:WBGene00171598 21ur-8018 No description available WB:WBGene00171599 21ur-6745 No description available WB:WBGene00171600 21ur-7449 No description available WB:WBGene00171601 21ur-7785 No description available WB:WBGene00171602 21ur-7841 No description available WB:WBGene00171603 21ur-10386 No description available WB:WBGene00171604 21ur-14273 No description available WB:WBGene00171605 21ur-6594 No description available WB:WBGene00171606 21ur-12784 No description available WB:WBGene00171607 21ur-12432 Enriched in neurons based on RNA-seq studies. WB:WBGene00171608 21ur-15558 No description available WB:WBGene00171609 21ur-14697 No description available WB:WBGene00171610 21ur-15551 No description available WB:WBGene00171611 21ur-12796 No description available WB:WBGene00171612 21ur-14545 No description available WB:WBGene00171613 21ur-5697 No description available WB:WBGene00171614 21ur-6963 No description available WB:WBGene00171615 21ur-9969 No description available WB:WBGene00171616 21ur-8603 No description available WB:WBGene00171617 21ur-13850 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00171618 21ur-11770 No description available WB:WBGene00171619 21ur-11297 No description available WB:WBGene00171620 21ur-13511 No description available WB:WBGene00171621 21ur-15078 No description available WB:WBGene00171622 21ur-12252 No description available WB:WBGene00171623 21ur-6519 No description available WB:WBGene00171624 21ur-6803 No description available WB:WBGene00171625 21ur-13207 No description available WB:WBGene00171626 21ur-15379 No description available WB:WBGene00171627 21ur-13334 No description available WB:WBGene00171628 21ur-9666 No description available WB:WBGene00171629 21ur-14163 No description available WB:WBGene00171630 21ur-7420 No description available WB:WBGene00171631 21ur-14131 No description available WB:WBGene00171632 21ur-6938 No description available WB:WBGene00171633 21ur-12557 No description available WB:WBGene00171634 21ur-7388 No description available WB:WBGene00171635 21ur-6330 No description available WB:WBGene00171636 21ur-8453 No description available WB:WBGene00171637 21ur-11318 No description available WB:WBGene00171638 21ur-15097 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00171639 21ur-7921 No description available WB:WBGene00171640 21ur-5837 No description available WB:WBGene00171641 21ur-10012 No description available WB:WBGene00171642 21ur-13463 No description available WB:WBGene00171643 21ur-5755 No description available WB:WBGene00171644 21ur-8469 Is affected by set-2 based on RNA-seq studies. WB:WBGene00171645 21ur-5626 No description available WB:WBGene00171646 21ur-7305 No description available WB:WBGene00171647 21ur-5482 No description available WB:WBGene00171648 21ur-15485 No description available WB:WBGene00171649 21ur-5636 No description available WB:WBGene00171650 21ur-5786 No description available WB:WBGene00171651 21ur-9513 No description available WB:WBGene00171652 21ur-10693 No description available WB:WBGene00171653 21ur-7762 No description available WB:WBGene00171654 21ur-7642 No description available WB:WBGene00171655 21ur-6894 No description available WB:WBGene00171656 21ur-11939 No description available WB:WBGene00171657 21ur-14537 No description available WB:WBGene00171658 21ur-6307 No description available WB:WBGene00171659 21ur-7143 No description available WB:WBGene00171660 21ur-6406 No description available WB:WBGene00171661 21ur-8159 No description available WB:WBGene00171662 21ur-11595 No description available WB:WBGene00171663 21ur-15317 No description available WB:WBGene00171664 21ur-13347 No description available WB:WBGene00171665 21ur-7711 No description available WB:WBGene00171666 21ur-10590 No description available WB:WBGene00171667 21ur-15675 No description available WB:WBGene00171668 21ur-14337 No description available WB:WBGene00171669 21ur-15105 No description available WB:WBGene00171670 21ur-9387 No description available WB:WBGene00171671 21ur-12655 No description available WB:WBGene00171672 21ur-7277 No description available WB:WBGene00171673 21ur-6376 No description available WB:WBGene00171674 21ur-15475 No description available WB:WBGene00171675 21ur-13336 No description available WB:WBGene00171676 21ur-12056 No description available WB:WBGene00171677 21ur-9343 No description available WB:WBGene00171678 21ur-11100 No description available WB:WBGene00171679 21ur-13548 No description available WB:WBGene00171680 21ur-6916 No description available WB:WBGene00171681 21ur-6424 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00171682 21ur-5465 No description available WB:WBGene00171683 21ur-10241 No description available WB:WBGene00171684 21ur-13766 No description available WB:WBGene00171685 21ur-7444 No description available WB:WBGene00171686 21ur-7285 No description available WB:WBGene00171687 21ur-13811 No description available WB:WBGene00171688 21ur-14835 No description available WB:WBGene00171689 21ur-9920 No description available WB:WBGene00171690 21ur-5924 No description available WB:WBGene00171691 21ur-8075 No description available WB:WBGene00171692 21ur-14906 No description available WB:WBGene00171693 21ur-10555 No description available WB:WBGene00171694 21ur-6875 No description available WB:WBGene00171695 21ur-11720 No description available WB:WBGene00171696 21ur-12175 No description available WB:WBGene00171697 21ur-13254 No description available WB:WBGene00171698 21ur-13418 No description available WB:WBGene00171699 21ur-7962 No description available WB:WBGene00171700 21ur-10199 No description available WB:WBGene00171701 21ur-14658 No description available WB:WBGene00171702 21ur-14128 No description available WB:WBGene00171703 21ur-14719 No description available WB:WBGene00171704 21ur-13087 No description available WB:WBGene00171705 21ur-8700 No description available WB:WBGene00171706 21ur-9220 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00171707 21ur-8991 No description available WB:WBGene00171708 21ur-14121 No description available WB:WBGene00171709 21ur-6854 Enriched in neurons based on RNA-seq studies. WB:WBGene00171710 21ur-11672 No description available WB:WBGene00171712 21ur-13554 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00171713 21ur-7631 Is affected by eat-2 based on microarray studies. WB:WBGene00171714 21ur-10157 No description available WB:WBGene00171715 21ur-5693 No description available WB:WBGene00171716 21ur-10205 No description available WB:WBGene00171717 21ur-7272 Is affected by met-2 based on RNA-seq studies. WB:WBGene00171718 21ur-11165 No description available WB:WBGene00171719 21ur-11658 No description available WB:WBGene00171720 21ur-11915 No description available WB:WBGene00171721 21ur-15320 No description available WB:WBGene00171722 21ur-10681 No description available WB:WBGene00171723 21ur-7828 No description available WB:WBGene00171724 21ur-14073 No description available WB:WBGene00171725 21ur-7491 No description available WB:WBGene00171726 21ur-7529 No description available WB:WBGene00171727 21ur-14305 No description available WB:WBGene00171728 21ur-5553 No description available WB:WBGene00171729 21ur-6213 No description available WB:WBGene00171730 21ur-8553 No description available WB:WBGene00171731 21ur-9818 No description available WB:WBGene00171732 21ur-8379 Enriched in neurons based on RNA-seq studies. WB:WBGene00171733 21ur-15457 No description available WB:WBGene00171734 21ur-7620 No description available WB:WBGene00171735 21ur-9694 No description available WB:WBGene00171736 21ur-7350 No description available WB:WBGene00171737 21ur-12391 No description available WB:WBGene00171738 21ur-12820 No description available WB:WBGene00171739 21ur-11885 No description available WB:WBGene00171740 21ur-6458 No description available WB:WBGene00171741 21ur-10408 No description available WB:WBGene00171742 21ur-13989 No description available WB:WBGene00171743 21ur-9464 No description available WB:WBGene00171744 21ur-10452 No description available WB:WBGene00171745 21ur-11637 No description available WB:WBGene00171746 21ur-12693 No description available WB:WBGene00171747 21ur-6828 No description available WB:WBGene00171748 21ur-11519 No description available WB:WBGene00171749 21ur-11424 No description available WB:WBGene00171750 21ur-13656 No description available WB:WBGene00171751 21ur-7105 No description available WB:WBGene00171752 21ur-15329 No description available WB:WBGene00171753 21ur-15272 No description available WB:WBGene00171754 21ur-7848 Enriched in neurons based on RNA-seq studies. WB:WBGene00171755 21ur-8735 No description available WB:WBGene00171756 21ur-7021 No description available WB:WBGene00171757 21ur-9146 No description available WB:WBGene00171758 21ur-10779 No description available WB:WBGene00171759 21ur-12828 No description available WB:WBGene00171760 21ur-7471 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00171761 21ur-11303 No description available WB:WBGene00171762 21ur-14417 No description available WB:WBGene00171763 21ur-5978 No description available WB:WBGene00171764 21ur-8998 No description available WB:WBGene00171765 21ur-10759 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00171766 21ur-10767 Enriched in neurons based on RNA-seq studies. WB:WBGene00171767 21ur-14257 No description available WB:WBGene00171768 21ur-5661 No description available WB:WBGene00171769 21ur-11711 No description available WB:WBGene00171770 21ur-9335 No description available WB:WBGene00171771 21ur-6984 No description available WB:WBGene00171772 21ur-6211 No description available WB:WBGene00171773 21ur-6543 No description available WB:WBGene00171774 21ur-13541 No description available WB:WBGene00171775 21ur-13588 No description available WB:WBGene00171776 21ur-9445 No description available WB:WBGene00171777 21ur-5778 No description available WB:WBGene00171778 21ur-11527 No description available WB:WBGene00171779 21ur-8969 No description available WB:WBGene00171780 21ur-9703 No description available WB:WBGene00171781 21ur-12595 No description available WB:WBGene00171782 21ur-7322 Is affected by daf-2 based on microarray studies. WB:WBGene00171783 21ur-11212 No description available WB:WBGene00171784 21ur-7081 No description available WB:WBGene00171785 21ur-11109 No description available WB:WBGene00171786 21ur-15243 Enriched in neurons based on RNA-seq studies. WB:WBGene00171787 21ur-8876 No description available WB:WBGene00171788 21ur-10284 No description available WB:WBGene00171789 21ur-12066 No description available WB:WBGene00171790 21ur-14647 No description available WB:WBGene00171791 21ur-9362 No description available WB:WBGene00171792 21ur-11961 No description available WB:WBGene00171793 21ur-7531 No description available WB:WBGene00171794 21ur-6099 No description available WB:WBGene00171795 21ur-13904 No description available WB:WBGene00171796 21ur-6259 No description available WB:WBGene00171797 21ur-12751 No description available WB:WBGene00171798 21ur-13604 No description available WB:WBGene00171799 21ur-6616 No description available WB:WBGene00171800 21ur-9048 No description available WB:WBGene00171801 21ur-7752 No description available WB:WBGene00171802 21ur-13112 No description available WB:WBGene00171803 21ur-9633 No description available WB:WBGene00171804 21ur-10047 No description available WB:WBGene00171805 21ur-7928 Is affected by daf-2 based on microarray studies. WB:WBGene00171806 21ur-9606 No description available WB:WBGene00171807 21ur-6127 Enriched in neurons based on RNA-seq studies. WB:WBGene00171809 21ur-12004 No description available WB:WBGene00171810 21ur-6765 Is affected by set-2 based on RNA-seq studies. WB:WBGene00171811 21ur-7464 Is affected by chd-3 based on RNA-seq studies. WB:WBGene00171812 21ur-5871 No description available WB:WBGene00171813 21ur-10216 No description available WB:WBGene00171814 21ur-15507 Is affected by eat-2 based on microarray studies. WB:WBGene00171815 21ur-12261 No description available WB:WBGene00171816 21ur-9572 Enriched in neurons based on RNA-seq studies. WB:WBGene00171817 21ur-11812 No description available WB:WBGene00171818 21ur-13877 No description available WB:WBGene00171819 21ur-11221 No description available WB:WBGene00171820 21ur-14879 Is affected by daf-2 based on microarray studies. WB:WBGene00171821 21ur-12376 No description available WB:WBGene00171822 21ur-13627 No description available WB:WBGene00171823 21ur-9380 No description available WB:WBGene00171824 21ur-9269 No description available WB:WBGene00171825 21ur-11399 No description available WB:WBGene00171826 21ur-10914 No description available WB:WBGene00171827 21ur-13518 No description available WB:WBGene00171828 21ur-7478 No description available WB:WBGene00171829 21ur-9121 Enriched in neurons based on RNA-seq studies. WB:WBGene00171830 21ur-12905 No description available WB:WBGene00171831 21ur-8921 No description available WB:WBGene00171832 21ur-8582 No description available WB:WBGene00171833 21ur-10947 No description available WB:WBGene00171834 21ur-11876 No description available WB:WBGene00171835 21ur-7178 No description available WB:WBGene00171836 21ur-14886 No description available WB:WBGene00171837 21ur-10231 No description available WB:WBGene00171838 21ur-12622 No description available WB:WBGene00171839 21ur-6568 No description available WB:WBGene00171840 21ur-6639 No description available WB:WBGene00171841 21ur-5973 Is affected by daf-2 based on microarray studies. WB:WBGene00171842 21ur-7573 No description available WB:WBGene00171843 21ur-10401 No description available WB:WBGene00171844 21ur-9092 No description available WB:WBGene00171845 21ur-15191 No description available WB:WBGene00171846 21ur-15637 No description available WB:WBGene00171847 21ur-7121 No description available WB:WBGene00171848 21ur-9756 No description available WB:WBGene00171849 21ur-10645 No description available WB:WBGene00171850 21ur-9084 No description available WB:WBGene00171851 21ur-7235 No description available WB:WBGene00171852 21ur-6289 No description available WB:WBGene00171853 21ur-5986 No description available WB:WBGene00171854 21ur-11433 No description available WB:WBGene00171855 21ur-14017 No description available WB:WBGene00171856 21ur-5713 No description available WB:WBGene00171857 21ur-11392 No description available WB:WBGene00171858 21ur-12158 No description available WB:WBGene00171859 21ur-8836 No description available WB:WBGene00171860 21ur-15163 No description available WB:WBGene00171861 21ur-10150 No description available WB:WBGene00171862 21ur-12678 No description available WB:WBGene00171863 21ur-6860 No description available WB:WBGene00171864 21ur-10674 No description available WB:WBGene00171865 21ur-8152 No description available WB:WBGene00171866 21ur-10907 No description available WB:WBGene00171867 21ur-14786 No description available WB:WBGene00171868 21ur-12187 No description available WB:WBGene00171869 21ur-15257 No description available WB:WBGene00171870 21ur-10363 No description available WB:WBGene00171871 21ur-8959 No description available WB:WBGene00171872 21ur-11085 No description available WB:WBGene00171873 21ur-13106 No description available WB:WBGene00171875 21ur-10112 No description available WB:WBGene00171876 21ur-10483 No description available WB:WBGene00171877 21ur-11530 No description available WB:WBGene00171878 21ur-7160 No description available WB:WBGene00171879 21ur-6033 No description available WB:WBGene00171880 21ur-12010 No description available WB:WBGene00171881 21ur-7599 No description available WB:WBGene00171882 21ur-8481 No description available WB:WBGene00171883 21ur-5768 No description available WB:WBGene00171884 21ur-6235 No description available WB:WBGene00171885 21ur-15455 No description available WB:WBGene00171886 21ur-9296 No description available WB:WBGene00171887 21ur-11401 No description available WB:WBGene00171888 21ur-9813 No description available WB:WBGene00171889 21ur-10920 No description available WB:WBGene00171890 21ur-9852 No description available WB:WBGene00171891 21ur-6108 No description available WB:WBGene00171892 21ur-7716 No description available WB:WBGene00171893 21ur-6921 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00171894 21ur-12967 No description available WB:WBGene00171895 21ur-11311 No description available WB:WBGene00171896 21ur-12302 No description available WB:WBGene00171897 21ur-13030 No description available WB:WBGene00171898 21ur-13212 No description available WB:WBGene00171899 21ur-6907 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00171900 21ur-11364 No description available WB:WBGene00171901 21ur-5740 No description available WB:WBGene00171902 21ur-15521 No description available WB:WBGene00171903 21ur-11102 No description available WB:WBGene00171904 21ur-14393 No description available WB:WBGene00171905 21ur-7339 Enriched in neurons based on RNA-seq studies. WB:WBGene00171906 21ur-12442 No description available WB:WBGene00171907 21ur-6037 No description available WB:WBGene00171908 21ur-10089 No description available WB:WBGene00171909 21ur-15405 No description available WB:WBGene00171910 21ur-13089 No description available WB:WBGene00171911 21ur-5890 No description available WB:WBGene00171912 21ur-11856 No description available WB:WBGene00171913 21ur-9539 No description available WB:WBGene00171914 21ur-10228 No description available WB:WBGene00171915 21ur-7071 No description available WB:WBGene00171916 21ur-7217 Is affected by several genes including hsf-1; lem-2; and emr-1 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies. WB:WBGene00171917 21ur-14115 No description available WB:WBGene00171918 21ur-13922 Is affected by several genes including set-2; lem-2; and emr-1 based on RNA-seq studies. WB:WBGene00171919 21ur-8620 No description available WB:WBGene00171920 21ur-6557 No description available WB:WBGene00171921 21ur-12656 No description available WB:WBGene00171922 21ur-11249 No description available WB:WBGene00171923 21ur-8162 No description available WB:WBGene00171924 21ur-14702 No description available WB:WBGene00171925 21ur-13689 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00171926 21ur-12295 Is affected by eat-2 based on microarray studies. WB:WBGene00171927 21ur-8130 No description available WB:WBGene00171928 21ur-9952 No description available WB:WBGene00171929 21ur-13321 Is affected by cpl-1 based on RNA-seq studies. Is affected by Tamoxifen based on RNA-seq studies. WB:WBGene00171930 21ur-5497 No description available WB:WBGene00171931 21ur-11230 No description available WB:WBGene00171932 21ur-13670 No description available WB:WBGene00171933 21ur-6591 No description available WB:WBGene00171934 21ur-6427 Is affected by daf-2 based on microarray studies. WB:WBGene00171935 21ur-14201 No description available WB:WBGene00171936 21ur-5828 Enriched in neurons based on RNA-seq studies. WB:WBGene00171937 21ur-8658 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00171938 21ur-11843 No description available WB:WBGene00171939 21ur-7023 Enriched in neurons based on RNA-seq studies. WB:WBGene00171940 21ur-11474 No description available WB:WBGene00171941 21ur-8163 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00171942 21ur-10468 No description available WB:WBGene00171943 21ur-12700 No description available WB:WBGene00171944 21ur-5811 No description available WB:WBGene00171945 21ur-8631 No description available WB:WBGene00171946 21ur-7131 Enriched in RIM and RMF based on single-cell RNA-seq studies. WB:WBGene00171947 21ur-12418 No description available WB:WBGene00171948 21ur-6976 No description available WB:WBGene00171949 21ur-12457 No description available WB:WBGene00171950 21ur-8464 No description available WB:WBGene00171951 21ur-10354 No description available WB:WBGene00171952 21ur-14737 No description available WB:WBGene00171953 21ur-7332 No description available WB:WBGene00171954 21ur-7647 No description available WB:WBGene00171955 21ur-8626 No description available WB:WBGene00171956 21ur-13562 No description available WB:WBGene00171957 21ur-7747 No description available WB:WBGene00171958 21ur-9178 Enriched in neurons based on RNA-seq studies. WB:WBGene00171959 21ur-11760 No description available WB:WBGene00171960 21ur-15125 No description available WB:WBGene00171961 21ur-8638 No description available WB:WBGene00171962 21ur-10418 No description available WB:WBGene00171963 21ur-9959 No description available WB:WBGene00171964 21ur-10735 No description available WB:WBGene00171965 21ur-7002 No description available WB:WBGene00171966 21ur-10835 No description available WB:WBGene00171967 21ur-8009 No description available WB:WBGene00171968 21ur-7167 Enriched in neurons based on RNA-seq studies. WB:WBGene00171969 21ur-10099 No description available WB:WBGene00171970 21ur-5897 No description available WB:WBGene00171971 21ur-10326 No description available WB:WBGene00171972 21ur-13839 No description available WB:WBGene00171973 21ur-10788 No description available WB:WBGene00171974 21ur-14618 No description available WB:WBGene00171975 21ur-12271 No description available WB:WBGene00171976 21ur-8508 No description available WB:WBGene00171977 21ur-13210 No description available WB:WBGene00171978 21ur-13531 No description available WB:WBGene00171979 21ur-14642 No description available WB:WBGene00171980 21ur-6040 No description available WB:WBGene00171981 21ur-9823 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00171982 21ur-11936 No description available WB:WBGene00171983 21ur-9843 No description available WB:WBGene00171984 21ur-15583 Is affected by lem-2; emr-1; and spt-16 based on RNA-seq studies. WB:WBGene00171985 21ur-13313 No description available WB:WBGene00171986 21ur-13325 No description available WB:WBGene00171987 21ur-6846 No description available WB:WBGene00171988 21ur-5667 No description available WB:WBGene00171989 21ur-8687 No description available WB:WBGene00171990 21ur-9943 No description available WB:WBGene00171991 21ur-6580 No description available WB:WBGene00171992 21ur-6206 No description available WB:WBGene00171993 21ur-14727 No description available WB:WBGene00171994 21ur-13381 No description available WB:WBGene00171995 21ur-6521 No description available WB:WBGene00171996 21ur-11195 No description available WB:WBGene00171997 21ur-9820 No description available WB:WBGene00171998 21ur-14213 No description available WB:WBGene00171999 21ur-5643 No description available WB:WBGene00172000 21ur-15235 No description available WB:WBGene00172001 21ur-9596 No description available WB:WBGene00172002 21ur-12722 No description available WB:WBGene00172003 21ur-10847 No description available WB:WBGene00172004 21ur-6865 No description available WB:WBGene00172006 21ur-14427 No description available WB:WBGene00172007 21ur-10500 No description available WB:WBGene00172008 21ur-8733 No description available WB:WBGene00172009 21ur-14460 No description available WB:WBGene00172010 21ur-11520 No description available WB:WBGene00172011 21ur-12732 No description available WB:WBGene00172012 21ur-9360 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172013 21ur-11580 No description available WB:WBGene00172014 21ur-14589 No description available WB:WBGene00172015 21ur-11681 No description available WB:WBGene00172016 21ur-14881 No description available WB:WBGene00172017 21ur-14187 No description available WB:WBGene00172018 21ur-10719 No description available WB:WBGene00172019 21ur-11679 No description available WB:WBGene00172020 21ur-14296 No description available WB:WBGene00172021 21ur-13318 No description available WB:WBGene00172022 21ur-14893 No description available WB:WBGene00172023 21ur-8137 No description available WB:WBGene00172024 21ur-11493 No description available WB:WBGene00172025 21ur-8283 No description available WB:WBGene00172026 21ur-13438 No description available WB:WBGene00172027 21ur-12002 No description available WB:WBGene00172028 21ur-11727 No description available WB:WBGene00172029 21ur-15591 No description available WB:WBGene00172030 21ur-12053 No description available WB:WBGene00172031 21ur-12123 No description available WB:WBGene00172032 21ur-9612 No description available WB:WBGene00172033 21ur-15468 No description available WB:WBGene00172034 21ur-9075 No description available WB:WBGene00172035 21ur-7542 No description available WB:WBGene00172036 21ur-6887 Enriched in neurons based on RNA-seq studies. WB:WBGene00172037 21ur-12102 No description available WB:WBGene00172038 21ur-10528 No description available WB:WBGene00172039 21ur-13910 Enriched in neurons based on RNA-seq studies. WB:WBGene00172040 21ur-6165 No description available WB:WBGene00172041 21ur-9973 No description available WB:WBGene00172042 21ur-7508 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00172043 21ur-8740 No description available WB:WBGene00172044 21ur-12727 No description available WB:WBGene00172045 21ur-6339 No description available WB:WBGene00172046 21ur-13363 No description available WB:WBGene00172047 21ur-13406 No description available WB:WBGene00172048 21ur-14055 No description available WB:WBGene00172049 21ur-12897 No description available WB:WBGene00172050 21ur-13855 No description available WB:WBGene00172051 21ur-9553 No description available WB:WBGene00172052 21ur-12317 No description available WB:WBGene00172053 21ur-11949 No description available WB:WBGene00172054 21ur-13016 No description available WB:WBGene00172055 21ur-5995 No description available WB:WBGene00172056 21ur-11978 Enriched in neurons based on RNA-seq studies. WB:WBGene00172057 21ur-7674 No description available WB:WBGene00172058 21ur-13730 No description available WB:WBGene00172059 21ur-9668 No description available WB:WBGene00172060 21ur-10020 No description available WB:WBGene00172061 21ur-6812 No description available WB:WBGene00172062 21ur-13579 No description available WB:WBGene00172063 21ur-6075 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00172064 21ur-6587 No description available WB:WBGene00172065 21ur-10507 No description available WB:WBGene00172066 21ur-12576 No description available WB:WBGene00172067 21ur-12774 No description available WB:WBGene00172068 21ur-15412 No description available WB:WBGene00172069 21ur-7851 No description available WB:WBGene00172070 21ur-8447 No description available WB:WBGene00172071 21ur-9504 No description available WB:WBGene00172072 21ur-13538 No description available WB:WBGene00172073 21ur-6751 No description available WB:WBGene00172074 21ur-8937 No description available WB:WBGene00172075 21ur-11242 No description available WB:WBGene00172076 21ur-12932 No description available WB:WBGene00172077 21ur-13149 No description available WB:WBGene00172078 21ur-12379 No description available WB:WBGene00172079 21ur-12133 No description available WB:WBGene00172080 21ur-14403 No description available WB:WBGene00172081 21ur-7808 No description available WB:WBGene00172082 21ur-12381 No description available WB:WBGene00172083 21ur-9019 No description available WB:WBGene00172084 21ur-11830 No description available WB:WBGene00172085 21ur-8513 No description available WB:WBGene00172086 21ur-12535 No description available WB:WBGene00172087 21ur-5609 No description available WB:WBGene00172088 21ur-14580 No description available WB:WBGene00172089 21ur-5831 No description available WB:WBGene00172090 21ur-10498 No description available WB:WBGene00172091 21ur-13446 No description available WB:WBGene00172092 21ur-12794 No description available WB:WBGene00172093 21ur-15496 No description available WB:WBGene00172094 21ur-15180 No description available WB:WBGene00172095 21ur-5660 No description available WB:WBGene00172096 21ur-14474 No description available WB:WBGene00172097 21ur-9845 No description available WB:WBGene00172098 21ur-14006 Enriched in neurons based on RNA-seq studies. WB:WBGene00172099 21ur-8930 No description available WB:WBGene00172100 21ur-6773 No description available WB:WBGene00172101 21ur-6404 No description available WB:WBGene00172102 21ur-11552 No description available WB:WBGene00172103 21ur-7664 No description available WB:WBGene00172104 21ur-11761 No description available WB:WBGene00172105 21ur-11940 No description available WB:WBGene00172106 21ur-6534 No description available WB:WBGene00172107 21ur-6439 No description available WB:WBGene00172108 21ur-8236 No description available WB:WBGene00172109 21ur-8439 No description available WB:WBGene00172110 21ur-14340 No description available WB:WBGene00172111 21ur-9983 No description available WB:WBGene00172112 21ur-7065 No description available WB:WBGene00172113 21ur-13739 No description available WB:WBGene00172114 21ur-7555 No description available WB:WBGene00172115 21ur-9255 No description available WB:WBGene00172116 21ur-14730 No description available WB:WBGene00172117 21ur-8226 No description available WB:WBGene00172118 21ur-14220 No description available WB:WBGene00172119 21ur-12137 No description available WB:WBGene00172120 21ur-13289 No description available WB:WBGene00172121 21ur-11810 No description available WB:WBGene00172122 21ur-12715 No description available WB:WBGene00172123 21ur-8081 No description available WB:WBGene00172124 21ur-8718 No description available WB:WBGene00172125 21ur-9179 No description available WB:WBGene00172126 21ur-11906 No description available WB:WBGene00172127 21ur-6257 No description available WB:WBGene00172128 21ur-13863 No description available WB:WBGene00172129 21ur-15483 No description available WB:WBGene00172130 21ur-12663 No description available WB:WBGene00172131 21ur-7488 No description available WB:WBGene00172132 21ur-6549 No description available WB:WBGene00172133 21ur-14570 No description available WB:WBGene00172134 21ur-13049 No description available WB:WBGene00172135 21ur-6542 No description available WB:WBGene00172136 21ur-6357 Enriched in neurons based on RNA-seq studies. WB:WBGene00172137 21ur-9277 No description available WB:WBGene00172138 21ur-12854 No description available WB:WBGene00172139 21ur-10999 No description available WB:WBGene00172140 21ur-14302 No description available WB:WBGene00172141 21ur-7015 No description available WB:WBGene00172142 21ur-7205 No description available WB:WBGene00172143 21ur-13755 No description available WB:WBGene00172144 21ur-12018 No description available WB:WBGene00172145 21ur-12830 Enriched in AFD based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00172146 21ur-13080 No description available WB:WBGene00172147 21ur-5952 No description available WB:WBGene00172148 21ur-10521 No description available WB:WBGene00172149 21ur-8427 No description available WB:WBGene00172150 21ur-10454 No description available WB:WBGene00172151 21ur-13727 No description available WB:WBGene00172152 21ur-9933 No description available WB:WBGene00172153 21ur-14771 No description available WB:WBGene00172154 21ur-9601 Enriched in neurons based on RNA-seq studies. WB:WBGene00172155 21ur-11861 No description available WB:WBGene00172156 21ur-13709 No description available WB:WBGene00172157 21ur-6789 No description available WB:WBGene00172158 21ur-8674 No description available WB:WBGene00172159 21ur-11323 No description available WB:WBGene00172160 21ur-9734 No description available WB:WBGene00172161 21ur-12084 No description available WB:WBGene00172162 21ur-14995 No description available WB:WBGene00172163 21ur-14958 No description available WB:WBGene00172164 21ur-14717 Is affected by daf-2 based on microarray studies. WB:WBGene00172165 21ur-12816 No description available WB:WBGene00172166 21ur-5843 No description available WB:WBGene00172167 21ur-8434 No description available WB:WBGene00172168 21ur-10876 No description available WB:WBGene00172169 21ur-13751 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00172170 21ur-9859 No description available WB:WBGene00172171 21ur-12412 No description available WB:WBGene00172172 21ur-14992 No description available WB:WBGene00172173 21ur-13669 No description available WB:WBGene00172174 21ur-8491 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00172175 21ur-10065 No description available WB:WBGene00172176 21ur-7010 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00172177 21ur-12494 No description available WB:WBGene00172178 21ur-8246 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00172179 21ur-10351 No description available WB:WBGene00172180 21ur-5884 No description available WB:WBGene00172181 21ur-11568 No description available WB:WBGene00172182 21ur-15073 No description available WB:WBGene00172183 21ur-13478 No description available WB:WBGene00172184 21ur-13199 No description available WB:WBGene00172185 21ur-7157 No description available WB:WBGene00172186 21ur-10121 No description available WB:WBGene00172187 21ur-8841 No description available WB:WBGene00172188 21ur-13183 No description available WB:WBGene00172189 21ur-8883 No description available WB:WBGene00172190 21ur-12800 No description available WB:WBGene00172191 21ur-15085 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172192 21ur-13498 No description available WB:WBGene00172193 21ur-7241 No description available WB:WBGene00172194 21ur-11645 No description available WB:WBGene00172195 21ur-12689 No description available WB:WBGene00172196 21ur-15453 No description available WB:WBGene00172197 21ur-13660 No description available WB:WBGene00172198 21ur-8826 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00172199 21ur-6002 No description available WB:WBGene00172200 21ur-8774 No description available WB:WBGene00172201 21ur-14948 No description available WB:WBGene00172202 21ur-5941 No description available WB:WBGene00172203 21ur-8002 No description available WB:WBGene00172204 21ur-14127 No description available WB:WBGene00172205 21ur-5570 No description available WB:WBGene00172206 21ur-6053 No description available WB:WBGene00172207 21ur-15363 Enriched in neurons based on RNA-seq studies. Is affected by met-2 based on RNA-seq studies. WB:WBGene00172208 21ur-9099 No description available WB:WBGene00172209 21ur-12884 No description available WB:WBGene00172210 21ur-10221 No description available WB:WBGene00172211 21ur-13950 No description available WB:WBGene00172212 21ur-10109 Is affected by several genes including lin-29; set-2; and lem-2 based on RNA-seq studies. WB:WBGene00172213 21ur-8099 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172214 21ur-7854 No description available WB:WBGene00172215 21ur-8614 No description available WB:WBGene00172216 21ur-7186 No description available WB:WBGene00172217 21ur-12913 No description available WB:WBGene00172218 21ur-14358 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172219 21ur-5503 No description available WB:WBGene00172220 21ur-8802 No description available WB:WBGene00172221 21ur-6872 No description available WB:WBGene00172222 21ur-13690 No description available WB:WBGene00172223 21ur-11665 Enriched in neurons based on RNA-seq studies. Is affected by spr-5 based on RNA-seq studies. WB:WBGene00172224 21ur-14389 No description available WB:WBGene00172225 21ur-8547 No description available WB:WBGene00172226 21ur-10738 No description available WB:WBGene00172227 21ur-7043 Enriched in sensory neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00172228 21ur-12239 No description available WB:WBGene00172229 21ur-14158 No description available WB:WBGene00172230 21ur-14349 No description available WB:WBGene00172231 21ur-14081 No description available WB:WBGene00172232 21ur-6946 No description available WB:WBGene00172233 21ur-14013 No description available WB:WBGene00172234 21ur-7410 No description available WB:WBGene00172235 21ur-11826 No description available WB:WBGene00172236 21ur-14467 No description available WB:WBGene00172237 21ur-6484 No description available WB:WBGene00172238 21ur-9661 No description available WB:WBGene00172239 21ur-14143 No description available WB:WBGene00172240 21ur-5512 No description available WB:WBGene00172241 21ur-10810 No description available WB:WBGene00172242 21ur-9130 No description available WB:WBGene00172243 21ur-11074 No description available WB:WBGene00172244 21ur-10174 No description available WB:WBGene00172245 21ur-11922 No description available WB:WBGene00172246 21ur-7265 No description available WB:WBGene00172247 21ur-15359 No description available WB:WBGene00172248 21ur-11009 No description available WB:WBGene00172249 21ur-11243 No description available WB:WBGene00172250 21ur-7639 No description available WB:WBGene00172251 21ur-12049 No description available WB:WBGene00172252 21ur-7257 Enriched in neurons based on RNA-seq studies. WB:WBGene00172253 21ur-14578 No description available WB:WBGene00172254 21ur-9726 No description available WB:WBGene00172255 21ur-5685 No description available WB:WBGene00172256 21ur-8272 No description available WB:WBGene00172257 21ur-15336 Enriched in neurons based on RNA-seq studies. WB:WBGene00172258 21ur-9119 Is affected by ikb-1 and nfki-1 based on RNA-seq studies. WB:WBGene00172259 21ur-13174 No description available WB:WBGene00172260 21ur-8521 No description available WB:WBGene00172261 21ur-12559 No description available WB:WBGene00172262 21ur-11785 No description available WB:WBGene00172263 21ur-10883 Enriched in neurons based on RNA-seq studies. WB:WBGene00172264 21ur-10961 No description available WB:WBGene00172265 21ur-10553 No description available WB:WBGene00172266 21ur-14688 No description available WB:WBGene00172267 21ur-14594 No description available WB:WBGene00172268 21ur-14750 No description available WB:WBGene00172269 21ur-9673 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172270 21ur-9473 No description available WB:WBGene00172271 21ur-7600 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00172272 21ur-11387 No description available WB:WBGene00172273 21ur-8908 No description available WB:WBGene00172274 21ur-5948 No description available WB:WBGene00172275 21ur-12792 No description available WB:WBGene00172276 21ur-7312 No description available WB:WBGene00172277 21ur-14982 No description available WB:WBGene00172278 21ur-12680 Enriched in neurons based on RNA-seq studies. WB:WBGene00172279 21ur-10880 No description available WB:WBGene00172280 21ur-9835 No description available WB:WBGene00172281 21ur-6721 No description available WB:WBGene00172282 21ur-11767 No description available WB:WBGene00172283 21ur-15653 No description available WB:WBGene00172284 21ur-15698 No description available WB:WBGene00172285 21ur-15638 No description available WB:WBGene00172286 21ur-6246 No description available WB:WBGene00172287 21ur-12247 No description available WB:WBGene00172288 21ur-9053 No description available WB:WBGene00172289 21ur-12554 No description available WB:WBGene00172290 21ur-13393 No description available WB:WBGene00172291 21ur-14401 No description available WB:WBGene00172292 21ur-7814 No description available WB:WBGene00172293 21ur-8668 No description available WB:WBGene00172294 21ur-10432 Is affected by ints-5 based on RNA-seq studies. WB:WBGene00172295 21ur-13492 No description available WB:WBGene00172296 21ur-8767 No description available WB:WBGene00172297 21ur-11994 No description available WB:WBGene00172298 21ur-12489 No description available WB:WBGene00172299 21ur-7091 No description available WB:WBGene00172300 21ur-8116 No description available WB:WBGene00172301 21ur-11145 No description available WB:WBGene00172302 21ur-6342 No description available WB:WBGene00172303 21ur-11963 No description available WB:WBGene00172304 21ur-13295 No description available WB:WBGene00172305 21ur-15350 No description available WB:WBGene00172306 21ur-14247 No description available WB:WBGene00172307 21ur-11802 No description available WB:WBGene00172308 21ur-13827 No description available WB:WBGene00172309 21ur-6911 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00172310 21ur-7294 No description available WB:WBGene00172311 21ur-5721 No description available WB:WBGene00172312 21ur-11199 No description available WB:WBGene00172313 21ur-6550 No description available WB:WBGene00172314 21ur-13644 No description available WB:WBGene00172315 21ur-13832 No description available WB:WBGene00172316 21ur-11572 No description available WB:WBGene00172317 21ur-7691 No description available WB:WBGene00172318 21ur-8092 No description available WB:WBGene00172319 21ur-13928 No description available WB:WBGene00172320 21ur-9318 No description available WB:WBGene00172321 21ur-9476 Enriched in neurons based on RNA-seq studies. WB:WBGene00172322 21ur-12868 No description available WB:WBGene00172323 21ur-13100 No description available WB:WBGene00172324 21ur-7778 No description available WB:WBGene00172325 21ur-10169 No description available WB:WBGene00172326 21ur-9313 No description available WB:WBGene00172327 21ur-12930 No description available WB:WBGene00172328 21ur-6177 No description available WB:WBGene00172329 21ur-9781 No description available WB:WBGene00172330 21ur-12269 No description available WB:WBGene00172331 21ur-15614 No description available WB:WBGene00172332 21ur-14249 No description available WB:WBGene00172333 21ur-5478 No description available WB:WBGene00172334 21ur-11274 No description available WB:WBGene00172335 21ur-15346 No description available WB:WBGene00172336 21ur-7777 No description available WB:WBGene00172337 21ur-6315 No description available WB:WBGene00172338 21ur-8528 No description available WB:WBGene00172339 21ur-7943 No description available WB:WBGene00172340 21ur-12748 No description available WB:WBGene00172341 21ur-15024 No description available WB:WBGene00172342 21ur-10630 No description available WB:WBGene00172343 21ur-5549 No description available WB:WBGene00172344 21ur-14197 No description available WB:WBGene00172345 21ur-15137 No description available WB:WBGene00172346 21ur-6966 No description available WB:WBGene00172347 21ur-9720 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00172348 21ur-12166 No description available WB:WBGene00172349 21ur-7225 No description available WB:WBGene00172350 21ur-5747 No description available WB:WBGene00172351 21ur-14848 No description available WB:WBGene00172352 21ur-12401 No description available WB:WBGene00172353 21ur-14505 No description available WB:WBGene00172354 21ur-7565 Enriched in neurons based on RNA-seq studies. WB:WBGene00172355 21ur-9755 No description available WB:WBGene00172356 21ur-15393 No description available WB:WBGene00172357 21ur-12639 No description available WB:WBGene00172358 21ur-6692 No description available WB:WBGene00172359 21ur-13806 Enriched in neurons based on RNA-seq studies. WB:WBGene00172360 21ur-5612 No description available WB:WBGene00172361 21ur-7650 No description available WB:WBGene00172362 21ur-9398 No description available WB:WBGene00172363 21ur-11186 No description available WB:WBGene00172364 21ur-13792 No description available WB:WBGene00172365 21ur-5595 No description available WB:WBGene00172366 21ur-15299 No description available WB:WBGene00172367 21ur-15147 No description available WB:WBGene00172368 21ur-15080 No description available WB:WBGene00172369 21ur-7536 No description available WB:WBGene00172370 21ur-15528 No description available WB:WBGene00172371 21ur-15292 No description available WB:WBGene00172372 21ur-8504 No description available WB:WBGene00172373 21ur-6201 No description available WB:WBGene00172374 21ur-11930 No description available WB:WBGene00172375 21ur-10534 No description available WB:WBGene00172376 21ur-7558 No description available WB:WBGene00172377 21ur-9685 No description available WB:WBGene00172378 21ur-14398 No description available WB:WBGene00172379 21ur-14743 Enriched in neurons based on RNA-seq studies. WB:WBGene00172380 21ur-5520 No description available WB:WBGene00172381 21ur-5877 No description available WB:WBGene00172382 21ur-7834 No description available WB:WBGene00172383 21ur-14421 No description available WB:WBGene00172384 21ur-14637 No description available WB:WBGene00172385 21ur-8663 No description available WB:WBGene00172386 21ur-6453 No description available WB:WBGene00172387 21ur-8253 No description available WB:WBGene00172388 21ur-15167 Is affected by emr-1; lem-2; and hmg-3 based on RNA-seq studies. WB:WBGene00172389 21ur-13610 No description available WB:WBGene00172390 21ur-14922 No description available WB:WBGene00172391 21ur-7682 No description available WB:WBGene00172392 21ur-12408 No description available WB:WBGene00172393 21ur-11953 No description available WB:WBGene00172394 21ur-6975 No description available WB:WBGene00172395 21ur-5869 No description available WB:WBGene00172396 21ur-8303 No description available WB:WBGene00172397 21ur-10709 No description available WB:WBGene00172398 21ur-11500 No description available WB:WBGene00172399 21ur-10677 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00172400 21ur-11839 No description available WB:WBGene00172401 21ur-12112 No description available WB:WBGene00172402 21ur-14157 No description available WB:WBGene00172403 21ur-9368 No description available WB:WBGene00172404 21ur-5492 No description available WB:WBGene00172405 21ur-14239 No description available WB:WBGene00172406 21ur-15622 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00172407 21ur-5455 Enriched in neurons based on RNA-seq studies. WB:WBGene00172408 21ur-6388 No description available WB:WBGene00172409 21ur-15474 No description available WB:WBGene00172410 21ur-15617 Enriched in neurons based on RNA-seq studies. WB:WBGene00172411 21ur-10583 No description available WB:WBGene00172412 21ur-13424 No description available WB:WBGene00172413 21ur-10702 No description available WB:WBGene00172414 21ur-7221 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172415 21ur-13411 No description available WB:WBGene00172416 21ur-14175 No description available WB:WBGene00172417 21ur-11604 No description available WB:WBGene00172418 21ur-11702 No description available WB:WBGene00172419 21ur-12465 Enriched in neurons based on RNA-seq studies. WB:WBGene00172420 21ur-11751 No description available WB:WBGene00172421 21ur-7379 No description available WB:WBGene00172422 21ur-6117 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172423 21ur-8976 No description available WB:WBGene00172424 21ur-10015 No description available WB:WBGene00172425 21ur-10575 No description available WB:WBGene00172426 21ur-13190 No description available WB:WBGene00172427 21ur-10570 No description available WB:WBGene00172428 21ur-12872 No description available WB:WBGene00172429 21ur-15442 No description available WB:WBGene00172430 21ur-14437 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172431 21ur-5804 No description available WB:WBGene00172432 21ur-8478 No description available WB:WBGene00172433 21ur-7087 No description available WB:WBGene00172434 21ur-7569 No description available WB:WBGene00172435 21ur-8059 Enriched in neurons based on RNA-seq studies. WB:WBGene00172436 21ur-14681 No description available WB:WBGene00172437 21ur-7244 No description available WB:WBGene00172438 21ur-9002 No description available WB:WBGene00172439 21ur-12074 No description available WB:WBGene00172440 21ur-11416 No description available WB:WBGene00172441 21ur-13352 No description available WB:WBGene00172442 21ur-6273 No description available WB:WBGene00172443 21ur-8105 No description available WB:WBGene00172444 21ur-6492 No description available WB:WBGene00172445 21ur-15606 No description available WB:WBGene00172446 21ur-11589 No description available WB:WBGene00172447 21ur-12349 No description available WB:WBGene00172448 21ur-14553 Is affected by eat-2 based on microarray studies. WB:WBGene00172449 21ur-12952 No description available WB:WBGene00172450 21ur-10292 No description available WB:WBGene00172451 21ur-7113 No description available WB:WBGene00172452 21ur-12314 Enriched in neurons based on RNA-seq studies. WB:WBGene00172453 21ur-6565 No description available WB:WBGene00172454 21ur-11174 No description available WB:WBGene00172455 21ur-7865 No description available WB:WBGene00172456 21ur-13971 No description available WB:WBGene00172457 21ur-5910 Is affected by smn-1 and lpd-3 based on RNA-seq studies. WB:WBGene00172458 21ur-5840 No description available WB:WBGene00172459 21ur-6953 No description available WB:WBGene00172460 21ur-12753 No description available WB:WBGene00172462 21ur-5616 No description available WB:WBGene00172463 21ur-5870 No description available WB:WBGene00172464 21ur-7455 No description available WB:WBGene00172465 21ur-8404 No description available WB:WBGene00172466 21ur-12662 No description available WB:WBGene00172467 21ur-13301 No description available WB:WBGene00172468 21ur-6466 No description available WB:WBGene00172469 21ur-5862 No description available WB:WBGene00172470 21ur-10637 Enriched in neurons based on RNA-seq studies. WB:WBGene00172471 21ur-7407 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00172472 21ur-9749 Is affected by prx-5 based on RNA-seq studies. WB:WBGene00172473 21ur-7349 No description available WB:WBGene00172474 21ur-6308 No description available WB:WBGene00172475 21ur-12671 Enriched in neurons based on RNA-seq studies. WB:WBGene00172476 21ur-10044 No description available WB:WBGene00172477 21ur-9564 No description available WB:WBGene00172478 21ur-10661 No description available WB:WBGene00172479 21ur-12505 No description available WB:WBGene00172480 21ur-9647 No description available WB:WBGene00172481 21ur-14649 No description available WB:WBGene00172482 21ur-11541 No description available WB:WBGene00172483 21ur-11561 No description available WB:WBGene00172484 21ur-7458 No description available WB:WBGene00172485 21ur-14564 No description available WB:WBGene00172486 21ur-12128 No description available WB:WBGene00172487 21ur-6932 No description available WB:WBGene00172488 21ur-7934 No description available WB:WBGene00172489 21ur-11287 No description available WB:WBGene00172490 21ur-10869 No description available WB:WBGene00172491 21ur-8298 No description available WB:WBGene00172492 21ur-13305 No description available WB:WBGene00172493 21ur-14938 No description available WB:WBGene00172494 21ur-14446 No description available WB:WBGene00172495 21ur-14230 No description available WB:WBGene00172496 21ur-6839 No description available WB:WBGene00172497 21ur-8984 No description available WB:WBGene00172498 21ur-12518 No description available WB:WBGene00172499 21ur-6500 No description available WB:WBGene00172500 21ur-13590 No description available WB:WBGene00172501 21ur-5770 No description available WB:WBGene00172502 21ur-6368 No description available WB:WBGene00172503 21ur-15027 No description available WB:WBGene00172504 21ur-6192 No description available WB:WBGene00172505 21ur-15064 No description available WB:WBGene00172506 21ur-11344 No description available WB:WBGene00172507 21ur-9045 Enriched in neurons based on RNA-seq studies. WB:WBGene00172508 21ur-9752 No description available WB:WBGene00172509 21ur-7042 Enriched in neurons based on RNA-seq studies. WB:WBGene00172510 21ur-11980 No description available WB:WBGene00172511 21ur-13122 No description available WB:WBGene00172512 21ur-6374 No description available WB:WBGene00172513 21ur-8173 No description available WB:WBGene00172514 21ur-9140 No description available WB:WBGene00172515 21ur-10560 No description available WB:WBGene00172516 21ur-11602 No description available WB:WBGene00172517 21ur-10367 No description available WB:WBGene00172518 21ur-10214 No description available WB:WBGene00172519 21ur-13351 No description available WB:WBGene00172520 21ur-14419 No description available WB:WBGene00172521 21ur-5961 Enriched in neurons based on RNA-seq studies. WB:WBGene00172522 21ur-15505 No description available WB:WBGene00172523 21ur-15188 No description available WB:WBGene00172524 21ur-5468 No description available WB:WBGene00172525 21ur-13263 Is affected by daf-2 based on microarray studies. WB:WBGene00172526 21ur-9470 No description available WB:WBGene00172527 21ur-10773 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172528 21ur-13620 No description available WB:WBGene00172529 21ur-7945 No description available WB:WBGene00172530 21ur-14410 No description available WB:WBGene00172531 21ur-12417 No description available WB:WBGene00172532 21ur-15225 No description available WB:WBGene00172533 21ur-12826 No description available WB:WBGene00172534 21ur-10585 No description available WB:WBGene00172535 21ur-12394 No description available WB:WBGene00172536 21ur-7008 No description available WB:WBGene00172537 21ur-13629 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00172538 21ur-7575 No description available WB:WBGene00172539 21ur-5704 No description available WB:WBGene00172540 21ur-13432 No description available WB:WBGene00172541 21ur-6736 No description available WB:WBGene00172542 21ur-15662 No description available WB:WBGene00172543 21ur-14858 No description available WB:WBGene00172544 21ur-13383 No description available WB:WBGene00172545 21ur-11927 No description available WB:WBGene00172546 21ur-5691 Enriched in neurons based on RNA-seq studies. WB:WBGene00172547 21ur-14653 No description available WB:WBGene00172548 21ur-8964 No description available WB:WBGene00172549 21ur-6153 No description available WB:WBGene00172550 21ur-14492 No description available WB:WBGene00172551 21ur-5972 No description available WB:WBGene00172552 21ur-15277 No description available WB:WBGene00172553 21ur-7982 No description available WB:WBGene00172554 21ur-14734 No description available WB:WBGene00172555 21ur-9507 No description available WB:WBGene00172556 21ur-13506 No description available WB:WBGene00172557 21ur-11088 Enriched in neurons based on RNA-seq studies. WB:WBGene00172558 21ur-9934 No description available WB:WBGene00172559 21ur-12843 No description available WB:WBGene00172560 21ur-11639 No description available WB:WBGene00172561 21ur-10406 No description available WB:WBGene00172562 21ur-7965 No description available WB:WBGene00172563 21ur-9909 No description available WB:WBGene00172564 21ur-13743 No description available WB:WBGene00172565 21ur-5754 No description available WB:WBGene00172566 21ur-11444 No description available WB:WBGene00172567 21ur-12076 No description available WB:WBGene00172568 21ur-10002 No description available WB:WBGene00172569 21ur-6669 No description available WB:WBGene00172570 21ur-14767 No description available WB:WBGene00172571 21ur-10808 No description available WB:WBGene00172572 21ur-11169 No description available WB:WBGene00172573 21ur-11213 Enriched in neurons based on RNA-seq studies. WB:WBGene00172574 21ur-6361 No description available WB:WBGene00172575 21ur-12003 No description available WB:WBGene00172576 21ur-7787 No description available WB:WBGene00172577 21ur-7128 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00172578 21ur-11107 No description available WB:WBGene00172579 21ur-6516 No description available WB:WBGene00172580 21ur-10567 No description available WB:WBGene00172581 21ur-14457 No description available WB:WBGene00172582 21ur-12204 No description available WB:WBGene00172583 21ur-5709 No description available WB:WBGene00172584 21ur-11704 No description available WB:WBGene00172585 21ur-11824 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00172586 21ur-15177 No description available WB:WBGene00172587 21ur-7282 No description available WB:WBGene00172588 21ur-14251 No description available WB:WBGene00172589 21ur-10730 No description available WB:WBGene00172590 21ur-15089 No description available WB:WBGene00172591 21ur-7625 Enriched in neurons based on RNA-seq studies. WB:WBGene00172592 21ur-7352 No description available WB:WBGene00172593 21ur-7649 Enriched in neurons based on RNA-seq studies. WB:WBGene00172594 21ur-5644 No description available WB:WBGene00172595 21ur-9705 No description available WB:WBGene00172596 21ur-7417 No description available WB:WBGene00172597 21ur-10017 No description available WB:WBGene00172598 21ur-14715 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00172599 21ur-5674 No description available WB:WBGene00172600 21ur-15420 No description available WB:WBGene00172601 21ur-9928 No description available WB:WBGene00172602 21ur-10867 No description available WB:WBGene00172603 21ur-5738 No description available WB:WBGene00172604 21ur-13344 Enriched in neurons based on RNA-seq studies. WB:WBGene00172605 21ur-7319 No description available WB:WBGene00172606 21ur-6074 No description available WB:WBGene00172607 21ur-6997 No description available WB:WBGene00172608 21ur-15255 No description available WB:WBGene00172609 21ur-9397 No description available WB:WBGene00172610 21ur-6965 No description available WB:WBGene00172611 21ur-10117 Is affected by daf-2 based on microarray studies. WB:WBGene00172612 21ur-12254 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00172613 21ur-5988 No description available WB:WBGene00172614 21ur-9528 No description available WB:WBGene00172615 21ur-13115 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00172616 21ur-9305 No description available WB:WBGene00172617 21ur-9126 No description available WB:WBGene00172618 21ur-8982 Is affected by set-2 based on RNA-seq studies. WB:WBGene00172619 21ur-6599 No description available WB:WBGene00172620 21ur-5630 No description available WB:WBGene00172621 21ur-7825 No description available WB:WBGene00172622 21ur-10826 No description available WB:WBGene00172623 21ur-14194 No description available WB:WBGene00172624 21ur-5724 No description available WB:WBGene00172625 21ur-8468 No description available WB:WBGene00172626 21ur-9273 No description available WB:WBGene00172627 21ur-10042 No description available WB:WBGene00172628 21ur-9429 No description available WB:WBGene00172629 21ur-11238 No description available WB:WBGene00172630 21ur-10332 No description available WB:WBGene00172631 21ur-14499 No description available WB:WBGene00172632 21ur-7402 No description available WB:WBGene00172633 21ur-5994 No description available WB:WBGene00172634 21ur-11355 Enriched in neurons based on RNA-seq studies. WB:WBGene00172635 21ur-9747 Enriched in neurons based on RNA-seq studies. WB:WBGene00172636 21ur-12745 No description available WB:WBGene00172637 21ur-7355 No description available WB:WBGene00172638 21ur-15499 No description available WB:WBGene00172639 21ur-15130 No description available WB:WBGene00172640 21ur-8885 No description available WB:WBGene00172641 21ur-6546 No description available WB:WBGene00172642 21ur-10964 No description available WB:WBGene00172643 21ur-6477 No description available WB:WBGene00172644 21ur-10508 No description available WB:WBGene00172645 21ur-10512 No description available WB:WBGene00172646 21ur-12454 No description available WB:WBGene00172647 21ur-15447 No description available WB:WBGene00172648 21ur-15112 No description available WB:WBGene00172649 21ur-8645 Enriched in neurons based on RNA-seq studies. WB:WBGene00172650 21ur-12738 No description available WB:WBGene00172651 21ur-15529 No description available WB:WBGene00172652 21ur-13358 No description available WB:WBGene00172653 21ur-13563 No description available WB:WBGene00172654 21ur-15386 No description available WB:WBGene00172655 21ur-14760 Is affected by ins-11 and damt-1 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00172656 21ur-10361 No description available WB:WBGene00172657 21ur-10912 No description available WB:WBGene00172658 21ur-11438 No description available WB:WBGene00172659 21ur-12091 No description available WB:WBGene00172660 21ur-8103 No description available WB:WBGene00172661 21ur-7520 No description available WB:WBGene00172662 21ur-5746 No description available WB:WBGene00172663 21ur-12248 No description available WB:WBGene00172664 21ur-15038 No description available WB:WBGene00172665 21ur-14533 No description available WB:WBGene00172666 21ur-5624 No description available WB:WBGene00172667 21ur-5539 No description available WB:WBGene00172668 21ur-10499 No description available WB:WBGene00172669 21ur-15091 No description available WB:WBGene00172670 21ur-6274 Enriched in neurons based on RNA-seq studies. WB:WBGene00172671 21ur-10484 No description available WB:WBGene00172672 21ur-6821 No description available WB:WBGene00172673 21ur-13208 No description available WB:WBGene00172674 21ur-6164 No description available WB:WBGene00172675 21ur-5732 Enriched in neurons based on RNA-seq studies. WB:WBGene00172676 21ur-14674 No description available WB:WBGene00172677 21ur-5637 No description available WB:WBGene00172678 21ur-5507 No description available WB:WBGene00172679 21ur-9707 No description available WB:WBGene00172680 21ur-8953 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172681 21ur-7411 No description available WB:WBGene00172682 21ur-13814 No description available WB:WBGene00172683 21ur-5610 No description available WB:WBGene00172684 21ur-12945 No description available WB:WBGene00172685 21ur-10550 No description available WB:WBGene00172686 21ur-7179 No description available WB:WBGene00172687 21ur-11532 No description available WB:WBGene00172688 21ur-8584 No description available WB:WBGene00172689 21ur-9515 No description available WB:WBGene00172690 21ur-9229 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00172691 21ur-13803 No description available WB:WBGene00172692 21ur-9340 No description available WB:WBGene00172693 21ur-15635 No description available WB:WBGene00172694 21ur-11380 No description available WB:WBGene00172695 21ur-5716 No description available WB:WBGene00172696 21ur-6398 No description available WB:WBGene00172697 21ur-8181 No description available WB:WBGene00172698 21ur-12648 No description available WB:WBGene00172699 21ur-10819 No description available WB:WBGene00172700 21ur-13242 No description available WB:WBGene00172701 21ur-9613 No description available WB:WBGene00172702 21ur-9662 No description available WB:WBGene00172703 21ur-15587 No description available WB:WBGene00172704 21ur-15057 No description available WB:WBGene00172705 21ur-13940 No description available WB:WBGene00172706 21ur-10439 No description available WB:WBGene00172707 21ur-12324 No description available WB:WBGene00172708 21ur-12890 No description available WB:WBGene00172709 21ur-13544 No description available WB:WBGene00172710 21ur-11617 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172711 21ur-13831 No description available WB:WBGene00172712 21ur-15669 No description available WB:WBGene00172713 21ur-5511 No description available WB:WBGene00172714 21ur-13201 Is affected by set-2 based on RNA-seq studies. WB:WBGene00172715 21ur-10799 No description available WB:WBGene00172716 21ur-6740 No description available WB:WBGene00172717 21ur-10083 No description available WB:WBGene00172718 21ur-10394 No description available WB:WBGene00172719 21ur-8414 No description available WB:WBGene00172720 21ur-8531 No description available WB:WBGene00172721 21ur-9350 No description available WB:WBGene00172722 21ur-6869 No description available WB:WBGene00172723 21ur-8893 No description available WB:WBGene00172724 21ur-7270 No description available WB:WBGene00172725 21ur-13109 No description available WB:WBGene00172726 21ur-8262 No description available WB:WBGene00172727 21ur-12695 No description available WB:WBGene00172728 21ur-10643 No description available WB:WBGene00172729 21ur-15566 Is affected by several genes including pgl-1; glh-1; and hpl-2 based on RNA-seq studies. WB:WBGene00172730 21ur-8736 No description available WB:WBGene00172731 21ur-7382 No description available WB:WBGene00172732 21ur-6093 No description available WB:WBGene00172733 21ur-11131 No description available WB:WBGene00172734 21ur-14135 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00172735 21ur-15361 Is affected by daf-2 based on microarray studies. WB:WBGene00172736 21ur-15522 No description available WB:WBGene00172737 21ur-6214 No description available WB:WBGene00172738 21ur-8860 No description available WB:WBGene00172739 21ur-10072 No description available WB:WBGene00172740 21ur-11966 No description available WB:WBGene00172741 21ur-7386 No description available WB:WBGene00172742 21ur-11138 No description available WB:WBGene00172743 21ur-8089 No description available WB:WBGene00172744 21ur-11591 No description available WB:WBGene00172745 21ur-15288 No description available WB:WBGene00172746 21ur-13895 No description available WB:WBGene00172747 21ur-14489 Is affected by daf-2 based on microarray studies. WB:WBGene00172748 21ur-7443 No description available WB:WBGene00172749 21ur-6051 Enriched in neurons based on RNA-seq studies. WB:WBGene00172750 21ur-13247 No description available WB:WBGene00172751 21ur-13148 No description available WB:WBGene00172752 21ur-7860 No description available WB:WBGene00172753 21ur-12625 No description available WB:WBGene00172754 21ur-5678 No description available WB:WBGene00172755 21ur-14279 No description available WB:WBGene00172756 21ur-6140 No description available WB:WBGene00172757 21ur-8069 No description available WB:WBGene00172758 21ur-9807 No description available WB:WBGene00172759 21ur-11887 No description available WB:WBGene00172760 21ur-10343 No description available WB:WBGene00172761 21ur-8455 No description available WB:WBGene00172762 21ur-12528 No description available WB:WBGene00172763 21ur-13345 No description available WB:WBGene00172764 21ur-14692 No description available WB:WBGene00172765 21ur-9267 No description available WB:WBGene00172766 21ur-9325 No description available WB:WBGene00172767 21ur-12763 No description available WB:WBGene00172768 21ur-13613 No description available WB:WBGene00172769 21ur-8201 No description available WB:WBGene00172770 21ur-10360 Enriched in neurons based on RNA-seq studies. WB:WBGene00172771 21ur-7991 No description available WB:WBGene00172772 21ur-8801 No description available WB:WBGene00172773 21ur-10529 No description available WB:WBGene00172774 21ur-9025 No description available WB:WBGene00172775 21ur-11125 Enriched in neurons based on RNA-seq studies. WB:WBGene00172776 21ur-10308 No description available WB:WBGene00172777 21ur-13255 No description available WB:WBGene00172778 21ur-7887 No description available WB:WBGene00172779 21ur-9510 Is affected by bisphenol A based on RNA-seq studies. WB:WBGene00172780 21ur-11913 No description available WB:WBGene00172781 21ur-14335 No description available WB:WBGene00172782 21ur-6960 No description available WB:WBGene00172783 21ur-12238 No description available WB:WBGene00172784 21ur-7760 Enriched in neurons based on RNA-seq studies. WB:WBGene00172785 21ur-9800 Is affected by daf-2 based on microarray studies. WB:WBGene00172786 21ur-7644 No description available WB:WBGene00172787 21ur-6662 No description available WB:WBGene00172788 21ur-13654 No description available WB:WBGene00172789 21ur-6852 No description available WB:WBGene00172790 21ur-15324 No description available WB:WBGene00172791 21ur-9675 No description available WB:WBGene00172792 21ur-15437 No description available WB:WBGene00172793 21ur-13387 No description available WB:WBGene00172794 21ur-8538 No description available WB:WBGene00172795 21ur-7360 No description available WB:WBGene00172796 21ur-15103 No description available WB:WBGene00172797 21ur-8288 No description available WB:WBGene00172798 21ur-7623 No description available WB:WBGene00172799 21ur-11066 No description available WB:WBGene00172800 21ur-14145 No description available WB:WBGene00172801 21ur-14080 No description available WB:WBGene00172802 21ur-15327 No description available WB:WBGene00172803 21ur-6892 No description available WB:WBGene00172804 21ur-11755 No description available WB:WBGene00172805 21ur-12241 No description available WB:WBGene00172806 21ur-12783 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00172807 21ur-14357 No description available WB:WBGene00172808 21ur-6678 No description available WB:WBGene00172809 21ur-6356 No description available WB:WBGene00172810 21ur-10543 No description available WB:WBGene00172811 21ur-10142 No description available WB:WBGene00172812 21ur-14947 No description available WB:WBGene00172813 21ur-11610 No description available WB:WBGene00172814 21ur-12992 No description available WB:WBGene00172815 21ur-9448 No description available WB:WBGene00172816 21ur-13701 No description available WB:WBGene00172817 21ur-8211 No description available WB:WBGene00172818 21ur-15313 No description available WB:WBGene00172819 21ur-6344 Is affected by set-2 based on RNA-seq studies. WB:WBGene00172820 21ur-8499 No description available WB:WBGene00172821 21ur-14601 No description available WB:WBGene00172822 21ur-8710 No description available WB:WBGene00172823 21ur-6526 No description available WB:WBGene00172824 21ur-11883 No description available WB:WBGene00172825 21ur-14089 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00172826 21ur-9669 No description available WB:WBGene00172827 21ur-6877 No description available WB:WBGene00172828 21ur-13399 No description available WB:WBGene00172829 21ur-6038 No description available WB:WBGene00172830 21ur-10246 Enriched in neurons based on RNA-seq studies. WB:WBGene00172831 21ur-12054 No description available WB:WBGene00172832 21ur-15372 No description available WB:WBGene00172833 21ur-12708 No description available WB:WBGene00172834 21ur-15074 No description available WB:WBGene00172835 21ur-8758 Enriched in neurons based on RNA-seq studies. WB:WBGene00172836 21ur-14908 No description available WB:WBGene00172837 21ur-8540 No description available WB:WBGene00172838 21ur-13572 No description available WB:WBGene00172839 21ur-7276 No description available WB:WBGene00172840 21ur-9008 No description available WB:WBGene00172841 21ur-10134 No description available WB:WBGene00172842 21ur-12368 No description available WB:WBGene00172843 21ur-9024 No description available WB:WBGene00172844 21ur-9333 No description available WB:WBGene00172845 21ur-14501 No description available WB:WBGene00172846 21ur-7630 No description available WB:WBGene00172847 21ur-14668 No description available WB:WBGene00172848 21ur-11162 No description available WB:WBGene00172849 21ur-15315 No description available WB:WBGene00172850 21ur-7214 No description available WB:WBGene00172851 21ur-12545 No description available WB:WBGene00172852 21ur-12803 No description available WB:WBGene00172853 21ur-15693 No description available WB:WBGene00172854 21ur-12020 No description available WB:WBGene00172855 21ur-7436 No description available WB:WBGene00172856 21ur-7506 No description available WB:WBGene00172857 21ur-10572 No description available WB:WBGene00172858 21ur-11722 No description available WB:WBGene00172859 21ur-5562 No description available WB:WBGene00172860 21ur-12616 No description available WB:WBGene00172861 21ur-10786 Enriched in neurons based on RNA-seq studies. WB:WBGene00172862 21ur-14152 No description available WB:WBGene00172863 21ur-8555 No description available WB:WBGene00172864 21ur-9274 No description available WB:WBGene00172865 21ur-13864 No description available WB:WBGene00172866 21ur-9136 Enriched in neurons based on RNA-seq studies. WB:WBGene00172867 21ur-10622 No description available WB:WBGene00172868 21ur-14310 No description available WB:WBGene00172869 21ur-13752 No description available WB:WBGene00172870 21ur-12197 Enriched in neurons based on RNA-seq studies. WB:WBGene00172871 21ur-8784 No description available WB:WBGene00172872 21ur-8706 No description available WB:WBGene00172873 21ur-7582 No description available WB:WBGene00172874 21ur-14804 No description available WB:WBGene00172875 21ur-9533 No description available WB:WBGene00172876 21ur-9044 No description available WB:WBGene00172877 21ur-8859 No description available WB:WBGene00172878 21ur-12927 No description available WB:WBGene00172879 21ur-14180 No description available WB:WBGene00172880 21ur-13720 No description available WB:WBGene00172881 21ur-7738 No description available WB:WBGene00172882 21ur-6758 No description available WB:WBGene00172883 21ur-8372 No description available WB:WBGene00172884 21ur-13646 No description available WB:WBGene00172885 21ur-7917 Enriched in neurons based on RNA-seq studies. WB:WBGene00172886 21ur-15511 No description available WB:WBGene00172887 21ur-5911 No description available WB:WBGene00172888 21ur-15461 No description available WB:WBGene00172889 21ur-12831 No description available WB:WBGene00172890 21ur-14048 No description available WB:WBGene00172891 21ur-13404 No description available WB:WBGene00172892 21ur-13236 No description available WB:WBGene00172893 21ur-11628 No description available WB:WBGene00172894 21ur-12611 No description available WB:WBGene00172895 21ur-14864 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00172896 21ur-9456 No description available WB:WBGene00172897 21ur-5566 No description available WB:WBGene00172898 21ur-13965 No description available WB:WBGene00172899 21ur-11819 No description available WB:WBGene00172900 21ur-10263 No description available WB:WBGene00172901 21ur-10533 No description available WB:WBGene00172902 21ur-13296 No description available WB:WBGene00172903 21ur-11123 No description available WB:WBGene00172904 21ur-5658 No description available WB:WBGene00172905 21ur-14953 No description available WB:WBGene00172906 21ur-12427 No description available WB:WBGene00172907 21ur-14725 No description available WB:WBGene00172908 21ur-8699 No description available WB:WBGene00172909 21ur-11559 No description available WB:WBGene00172910 21ur-11228 No description available WB:WBGene00172911 21ur-8574 No description available WB:WBGene00172912 21ur-11539 No description available WB:WBGene00172913 21ur-12593 No description available WB:WBGene00172914 21ur-15128 No description available WB:WBGene00172915 21ur-9096 No description available WB:WBGene00172916 21ur-15306 No description available WB:WBGene00172917 21ur-6409 No description available WB:WBGene00172918 21ur-9462 No description available WB:WBGene00172919 21ur-10614 No description available WB:WBGene00172920 21ur-11054 No description available WB:WBGene00172921 21ur-9923 No description available WB:WBGene00172922 21ur-10909 No description available WB:WBGene00172923 21ur-9038 Is affected by set-2 based on RNA-seq studies. WB:WBGene00172924 21ur-13066 No description available WB:WBGene00172925 21ur-9484 No description available WB:WBGene00172926 21ur-11644 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00172927 21ur-7606 No description available WB:WBGene00172928 21ur-5939 Enriched in neurons based on RNA-seq studies. WB:WBGene00172929 21ur-14482 No description available WB:WBGene00172930 21ur-9560 No description available WB:WBGene00172931 21ur-6712 No description available WB:WBGene00172932 21ur-14510 No description available WB:WBGene00172933 21ur-8855 No description available WB:WBGene00172934 21ur-11775 No description available WB:WBGene00172935 21ur-13270 No description available WB:WBGene00172936 21ur-7196 No description available WB:WBGene00172937 21ur-15540 Enriched in neurons based on RNA-seq studies. WB:WBGene00172938 21ur-11870 No description available WB:WBGene00172939 21ur-14740 No description available WB:WBGene00172940 21ur-9788 Is affected by eat-2 based on microarray studies. WB:WBGene00172941 21ur-7977 No description available WB:WBGene00172942 21ur-12973 No description available WB:WBGene00172943 21ur-8035 Is affected by daf-2 based on microarray studies. WB:WBGene00172944 21ur-10986 No description available WB:WBGene00172945 21ur-13182 No description available WB:WBGene00172946 21ur-7169 No description available WB:WBGene00172947 21ur-13450 No description available WB:WBGene00172948 21ur-11445 No description available WB:WBGene00172949 21ur-10928 No description available WB:WBGene00172950 21ur-12860 No description available WB:WBGene00172951 21ur-7589 No description available WB:WBGene00172952 21ur-13140 No description available WB:WBGene00172953 21ur-9552 No description available WB:WBGene00172954 21ur-9998 No description available WB:WBGene00172955 21ur-12370 No description available WB:WBGene00172956 21ur-9288 No description available WB:WBGene00172957 21ur-11651 No description available WB:WBGene00172958 21ur-8752 No description available WB:WBGene00172959 21ur-6859 No description available WB:WBGene00172960 21ur-15139 No description available WB:WBGene00172961 21ur-10944 No description available WB:WBGene00172962 21ur-13499 No description available WB:WBGene00172963 21ur-7967 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00172964 21ur-6418 No description available WB:WBGene00172965 21ur-13695 No description available WB:WBGene00172966 21ur-5793 No description available WB:WBGene00172967 21ur-7792 No description available WB:WBGene00172968 21ur-8878 Enriched in neurons based on RNA-seq studies. WB:WBGene00172969 21ur-12082 No description available WB:WBGene00172970 21ur-10271 No description available WB:WBGene00172971 21ur-7110 No description available WB:WBGene00172972 21ur-11622 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00172973 21ur-11894 No description available WB:WBGene00172974 21ur-14090 No description available WB:WBGene00172975 21ur-15650 No description available WB:WBGene00172976 21ur-15366 No description available WB:WBGene00172977 21ur-7018 No description available WB:WBGene00172978 21ur-11547 No description available WB:WBGene00172979 21ur-13913 No description available WB:WBGene00172980 21ur-7794 No description available WB:WBGene00172981 21ur-10268 No description available WB:WBGene00172982 21ur-5513 No description available WB:WBGene00172983 21ur-11512 No description available WB:WBGene00172984 21ur-13459 No description available WB:WBGene00172985 21ur-5904 Enriched in neurons based on RNA-seq studies. WB:WBGene00172986 21ur-8342 No description available WB:WBGene00172987 21ur-11657 No description available WB:WBGene00172988 21ur-12263 No description available WB:WBGene00172989 21ur-9359 No description available WB:WBGene00172990 21ur-12033 No description available WB:WBGene00172991 21ur-8366 No description available WB:WBGene00172992 21ur-7237 No description available WB:WBGene00172993 21ur-15012 No description available WB:WBGene00172994 21ur-8587 No description available WB:WBGene00172995 21ur-14526 No description available WB:WBGene00172996 21ur-9010 No description available WB:WBGene00172997 21ur-10618 No description available WB:WBGene00172998 21ur-8494 No description available WB:WBGene00172999 21ur-7255 No description available WB:WBGene00173000 21ur-13175 Enriched in neurons based on RNA-seq studies. WB:WBGene00173001 21ur-7330 No description available WB:WBGene00173002 21ur-13376 Is affected by several genes including blmp-1; hmg-4; and hmg-3 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies. WB:WBGene00173003 21ur-8394 No description available WB:WBGene00173004 21ur-7317 No description available WB:WBGene00173005 21ur-12510 No description available WB:WBGene00173006 21ur-8313 No description available WB:WBGene00173007 21ur-14223 No description available WB:WBGene00173008 21ur-5585 No description available WB:WBGene00173009 21ur-6446 No description available WB:WBGene00173010 21ur-6298 No description available WB:WBGene00173011 21ur-9793 No description available WB:WBGene00173012 21ur-10970 No description available WB:WBGene00173013 21ur-10473 No description available WB:WBGene00173014 21ur-14853 No description available WB:WBGene00173015 21ur-11786 Is affected by let-418 based on RNA-seq studies. WB:WBGene00173016 21ur-14314 No description available WB:WBGene00173017 21ur-8024 No description available WB:WBGene00173018 21ur-8165 No description available WB:WBGene00173019 21ur-14891 No description available WB:WBGene00173020 21ur-11024 No description available WB:WBGene00173021 21ur-14593 No description available WB:WBGene00173022 21ur-6621 No description available WB:WBGene00173023 21ur-6014 No description available WB:WBGene00173024 21ur-8606 Enriched in neurons based on RNA-seq studies. WB:WBGene00173025 21ur-12961 No description available WB:WBGene00173026 21ur-13362 No description available WB:WBGene00173027 21ur-10325 No description available WB:WBGene00173028 21ur-10711 No description available WB:WBGene00173029 21ur-8780 No description available WB:WBGene00173030 21ur-8339 No description available WB:WBGene00173031 21ur-8160 Enriched in neurons based on RNA-seq studies. WB:WBGene00173032 21ur-9777 No description available WB:WBGene00173033 21ur-10183 No description available WB:WBGene00173034 21ur-13688 No description available WB:WBGene00173035 21ur-6687 No description available WB:WBGene00173036 21ur-14940 No description available WB:WBGene00173037 21ur-9111 No description available WB:WBGene00173038 21ur-9260 No description available WB:WBGene00173039 21ur-9864 No description available WB:WBGene00173040 21ur-7302 No description available WB:WBGene00173041 21ur-13596 No description available WB:WBGene00173042 21ur-6022 No description available WB:WBGene00173043 21ur-15556 No description available WB:WBGene00173044 21ur-12286 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00173045 21ur-6437 No description available WB:WBGene00173046 21ur-13882 No description available WB:WBGene00173047 21ur-9230 No description available WB:WBGene00173048 21ur-14138 No description available WB:WBGene00173049 21ur-10690 No description available WB:WBGene00173050 21ur-9003 Enriched in neurons based on RNA-seq studies. WB:WBGene00173051 21ur-11425 No description available WB:WBGene00173052 21ur-5966 No description available WB:WBGene00173053 21ur-12272 No description available WB:WBGene00173054 21ur-8381 No description available WB:WBGene00173055 21ur-14823 No description available WB:WBGene00173056 21ur-5854 No description available WB:WBGene00173057 21ur-14621 No description available WB:WBGene00173058 21ur-8846 No description available WB:WBGene00173059 21ur-11309 No description available WB:WBGene00173060 21ur-13962 No description available WB:WBGene00173061 21ur-12144 Enriched in neurons based on RNA-seq studies. WB:WBGene00173062 21ur-15287 No description available WB:WBGene00173063 21ur-7995 No description available WB:WBGene00173064 21ur-9968 No description available WB:WBGene00173065 21ur-6253 No description available WB:WBGene00173066 21ur-10337 No description available WB:WBGene00173067 21ur-8345 No description available WB:WBGene00173068 21ur-7780 No description available WB:WBGene00173069 21ur-11494 No description available WB:WBGene00173070 21ur-9559 No description available WB:WBGene00173071 21ur-7141 No description available WB:WBGene00173072 21ur-8484 No description available WB:WBGene00173073 21ur-13623 No description available WB:WBGene00173074 21ur-10697 Is affected by hmg-3 and nfki-1 based on RNA-seq studies. WB:WBGene00173075 21ur-14374 No description available WB:WBGene00173076 21ur-6062 No description available WB:WBGene00173077 21ur-7162 Enriched in neurons based on RNA-seq studies. WB:WBGene00173078 21ur-9104 No description available WB:WBGene00173079 21ur-9295 No description available WB:WBGene00173080 21ur-13636 No description available WB:WBGene00173081 21ur-13584 No description available WB:WBGene00173082 21ur-6694 No description available WB:WBGene00173083 21ur-15599 No description available WB:WBGene00173084 21ur-13520 No description available WB:WBGene00173085 21ur-8327 No description available WB:WBGene00173086 21ur-13371 No description available WB:WBGene00173087 21ur-15332 No description available WB:WBGene00173088 21ur-7923 No description available WB:WBGene00173089 21ur-6129 No description available WB:WBGene00173090 21ur-10376 No description available WB:WBGene00173091 21ur-10902 No description available WB:WBGene00173092 21ur-15381 No description available WB:WBGene00173093 21ur-11040 No description available WB:WBGene00173094 21ur-11033 No description available WB:WBGene00173095 21ur-7072 No description available WB:WBGene00173096 21ur-10518 No description available WB:WBGene00173097 21ur-6628 No description available WB:WBGene00173098 21ur-7704 No description available WB:WBGene00173099 21ur-11208 No description available WB:WBGene00173100 21ur-7596 No description available WB:WBGene00173101 21ur-12383 No description available WB:WBGene00173102 21ur-13568 No description available WB:WBGene00173103 21ur-7872 No description available WB:WBGene00173104 21ur-11713 No description available WB:WBGene00173105 21ur-10689 No description available WB:WBGene00173106 21ur-14662 No description available WB:WBGene00173107 21ur-14256 No description available WB:WBGene00173108 21ur-11203 No description available WB:WBGene00173109 21ur-10651 No description available WB:WBGene00173110 21ur-8881 No description available WB:WBGene00173111 21ur-14964 No description available WB:WBGene00173112 21ur-12605 No description available WB:WBGene00173113 21ur-12989 No description available WB:WBGene00173114 21ur-13944 No description available WB:WBGene00173115 21ur-13937 No description available WB:WBGene00173116 21ur-5895 No description available WB:WBGene00173117 21ur-11865 No description available WB:WBGene00173118 21ur-14837 No description available WB:WBGene00173119 21ur-8158 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00173120 21ur-9497 No description available WB:WBGene00173121 21ur-15206 No description available WB:WBGene00173122 21ur-7724 No description available WB:WBGene00173123 21ur-9151 No description available WB:WBGene00173124 21ur-12883 No description available WB:WBGene00173125 21ur-15548 No description available WB:WBGene00173126 21ur-11096 No description available WB:WBGene00173127 21ur-9987 No description available WB:WBGene00173128 21ur-6986 Enriched in neurons based on RNA-seq studies. WB:WBGene00173129 21ur-7425 No description available WB:WBGene00173130 21ur-6644 No description available WB:WBGene00173131 21ur-9597 No description available WB:WBGene00173132 21ur-8945 No description available WB:WBGene00173133 21ur-6592 No description available WB:WBGene00173134 21ur-9712 No description available WB:WBGene00173135 21ur-7060 Enriched in neurons based on RNA-seq studies. WB:WBGene00173136 21ur-11499 No description available WB:WBGene00173137 21ur-11503 No description available WB:WBGene00173138 21ur-8657 No description available WB:WBGene00173139 21ur-13076 No description available WB:WBGene00173140 21ur-12027 No description available WB:WBGene00173141 21ur-6391 No description available WB:WBGene00173142 21ur-14112 No description available WB:WBGene00173143 21ur-8822 No description available WB:WBGene00173144 21ur-5918 No description available WB:WBGene00173145 21ur-5729 Is affected by daf-2 based on microarray studies. WB:WBGene00173146 21ur-12631 No description available WB:WBGene00173147 21ur-15252 No description available WB:WBGene00173148 21ur-12184 No description available WB:WBGene00173149 21ur-12435 No description available WB:WBGene00173150 21ur-6632 No description available WB:WBGene00173151 21ur-6386 No description available WB:WBGene00173152 21ur-15131 No description available WB:WBGene00173153 21ur-8058 No description available WB:WBGene00173154 21ur-11404 No description available WB:WBGene00173155 21ur-12353 No description available WB:WBGene00173156 21ur-9416 No description available WB:WBGene00173157 21ur-9290 No description available WB:WBGene00173158 21ur-5558 No description available WB:WBGene00173159 21ur-6194 No description available WB:WBGene00173160 21ur-9061 No description available WB:WBGene00173161 21ur-14234 No description available WB:WBGene00173162 21ur-15041 No description available WB:WBGene00173163 21ur-14444 No description available WB:WBGene00173164 21ur-13983 No description available WB:WBGene00173165 21ur-7837 No description available WB:WBGene00173166 21ur-13794 No description available WB:WBGene00173167 21ur-9775 No description available WB:WBGene00173168 21ur-12110 No description available WB:WBGene00173169 21ur-9077 No description available WB:WBGene00173170 21ur-14615 No description available WB:WBGene00173171 21ur-6389 No description available WB:WBGene00173172 21ur-13976 Is affected by ins-11 based on RNA-seq studies. WB:WBGene00173173 21ur-14932 No description available WB:WBGene00173174 21ur-14232 No description available WB:WBGene00173175 21ur-7177 No description available WB:WBGene00173176 21ur-6203 Enriched in neurons based on RNA-seq studies. WB:WBGene00173177 21ur-13732 No description available WB:WBGene00173178 21ur-9525 No description available WB:WBGene00173179 21ur-7684 No description available WB:WBGene00173180 21ur-10635 No description available WB:WBGene00173181 21ur-14942 No description available WB:WBGene00173182 21ur-14898 No description available WB:WBGene00173183 21ur-14177 No description available WB:WBGene00173184 21ur-7405 No description available WB:WBGene00173185 21ur-7009 No description available WB:WBGene00173186 21ur-5874 No description available WB:WBGene00173187 21ur-9744 No description available WB:WBGene00173188 21ur-7501 No description available WB:WBGene00173189 21ur-14422 No description available WB:WBGene00173190 21ur-13878 No description available WB:WBGene00173191 21ur-8071 No description available WB:WBGene00173192 21ur-15627 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00173193 21ur-14936 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00173194 21ur-9374 No description available WB:WBGene00173195 21ur-12717 No description available WB:WBGene00173196 21ur-14634 No description available WB:WBGene00173197 21ur-5457 No description available WB:WBGene00173198 21ur-9574 No description available WB:WBGene00173199 21ur-10638 No description available WB:WBGene00173200 21ur-7556 No description available WB:WBGene00173201 21ur-13139 No description available WB:WBGene00173202 21ur-6810 No description available WB:WBGene00173203 21ur-12975 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00173204 21ur-7031 No description available WB:WBGene00173205 21ur-5664 No description available WB:WBGene00173206 21ur-9640 No description available WB:WBGene00173207 21ur-6994 No description available WB:WBGene00173208 21ur-11955 No description available WB:WBGene00173209 21ur-6603 No description available WB:WBGene00173210 21ur-11765 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00173211 21ur-12934 No description available WB:WBGene00173212 21ur-12857 No description available WB:WBGene00173213 21ur-8177 No description available WB:WBGene00173214 21ur-7512 No description available WB:WBGene00173215 21ur-6126 No description available WB:WBGene00173216 21ur-14408 No description available WB:WBGene00173217 21ur-13602 No description available WB:WBGene00173218 21ur-9224 No description available WB:WBGene00173219 21ur-8274 No description available WB:WBGene00173220 21ur-11750 No description available WB:WBGene00173221 21ur-9766 No description available WB:WBGene00173222 21ur-5776 No description available WB:WBGene00173223 21ur-11563 No description available WB:WBGene00173224 21ur-11410 No description available WB:WBGene00173225 21ur-8813 No description available WB:WBGene00173226 21ur-7952 No description available WB:WBGene00173227 21ur-13196 No description available WB:WBGene00173228 21ur-10434 No description available WB:WBGene00173229 21ur-14060 No description available WB:WBGene00173230 21ur-6569 No description available WB:WBGene00173231 21ur-11565 No description available WB:WBGene00173232 21ur-8592 No description available WB:WBGene00173233 21ur-6562 No description available WB:WBGene00173234 21ur-5859 No description available WB:WBGene00173235 21ur-12042 No description available WB:WBGene00173236 21ur-12870 No description available WB:WBGene00173237 21ur-13609 No description available WB:WBGene00173238 21ur-14920 No description available WB:WBGene00173239 21ur-8935 No description available WB:WBGene00173240 21ur-12160 No description available WB:WBGene00173241 21ur-13413 No description available WB:WBGene00173242 21ur-6710 No description available WB:WBGene00173243 21ur-9469 No description available WB:WBGene00173244 21ur-8108 No description available WB:WBGene00173245 21ur-13884 No description available WB:WBGene00173246 21ur-8554 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00173247 21ur-15498 No description available WB:WBGene00173248 21ur-14745 No description available WB:WBGene00173249 21ur-15611 No description available WB:WBGene00173250 21ur-7494 No description available WB:WBGene00173251 21ur-10980 No description available WB:WBGene00173252 21ur-8296 No description available WB:WBGene00173253 21ur-11240 No description available WB:WBGene00173254 21ur-9349 No description available WB:WBGene00173255 21ur-12683 No description available WB:WBGene00173256 21ur-15271 No description available WB:WBGene00173257 21ur-11112 No description available WB:WBGene00173258 21ur-7392 No description available WB:WBGene00173259 21ur-8694 No description available WB:WBGene00173260 21ur-11822 No description available WB:WBGene00173261 21ur-8402 No description available WB:WBGene00173262 21ur-12406 No description available WB:WBGene00173263 21ur-15608 No description available WB:WBGene00173264 21ur-10276 No description available WB:WBGene00173265 21ur-14263 No description available WB:WBGene00173266 21ur-8083 No description available WB:WBGene00173267 21ur-10703 No description available WB:WBGene00173268 21ur-6837 No description available WB:WBGene00173269 21ur-6423 No description available WB:WBGene00173270 21ur-7377 Is affected by set-2 based on RNA-seq studies. WB:WBGene00173271 21ur-14439 No description available WB:WBGene00173272 21ur-6188 No description available WB:WBGene00173273 21ur-8377 No description available WB:WBGene00173274 21ur-14572 No description available WB:WBGene00173275 21ur-6271 No description available WB:WBGene00173276 21ur-6060 No description available WB:WBGene00173277 21ur-15189 No description available WB:WBGene00173278 21ur-13353 No description available WB:WBGene00173279 21ur-13083 No description available WB:WBGene00173280 21ur-10604 No description available WB:WBGene00173281 21ur-11193 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00173282 21ur-14507 No description available WB:WBGene00173283 21ur-7228 Enriched in neurons based on RNA-seq studies. WB:WBGene00173284 21ur-9251 No description available WB:WBGene00173285 21ur-13598 No description available WB:WBGene00173286 21ur-6487 No description available WB:WBGene00173287 21ur-6462 No description available WB:WBGene00173288 21ur-15451 No description available WB:WBGene00173289 21ur-6468 No description available WB:WBGene00173290 21ur-13508 No description available WB:WBGene00173291 21ur-12325 No description available WB:WBGene00173292 21ur-7346 No description available WB:WBGene00173293 21ur-6196 Enriched in neurons based on RNA-seq studies. WB:WBGene00173294 21ur-10653 Is affected by wdr-5.1 and hlh-26 based on RNA-seq studies. WB:WBGene00173295 21ur-12503 No description available WB:WBGene00173296 21ur-13299 No description available WB:WBGene00173297 21ur-13779 No description available WB:WBGene00173298 21ur-13032 No description available WB:WBGene00173299 21ur-14442 No description available WB:WBGene00173300 21ur-9457 No description available WB:WBGene00173301 21ur-5541 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00173302 21ur-11686 No description available WB:WBGene00173303 21ur-14797 No description available WB:WBGene00173304 21ur-8966 No description available WB:WBGene00173305 21ur-9543 No description available WB:WBGene00173306 21ur-12954 No description available WB:WBGene00173307 21ur-15500 No description available WB:WBGene00173308 21ur-8666 No description available WB:WBGene00173309 21ur-13501 No description available WB:WBGene00173310 21ur-5881 No description available WB:WBGene00173311 21ur-7084 No description available WB:WBGene00173312 21ur-10757 No description available WB:WBGene00173313 21ur-7119 No description available WB:WBGene00173314 21ur-11968 No description available WB:WBGene00173315 21ur-7423 Enriched in neurons based on RNA-seq studies. WB:WBGene00173316 21ur-12929 No description available WB:WBGene00173317 21ur-8951 No description available WB:WBGene00173318 21ur-11986 No description available WB:WBGene00173319 21ur-6726 No description available WB:WBGene00173320 21ur-12818 No description available WB:WBGene00173321 21ur-7089 No description available WB:WBGene00173322 21ur-5471 No description available WB:WBGene00173323 21ur-10481 Enriched in neurons based on RNA-seq studies. WB:WBGene00173324 21ur-9885 No description available WB:WBGene00173325 21ur-7733 No description available WB:WBGene00173326 21ur-12345 No description available WB:WBGene00173327 21ur-14689 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00173328 21ur-5485 No description available WB:WBGene00173329 21ur-7856 No description available WB:WBGene00173330 21ur-11731 No description available WB:WBGene00173331 21ur-9656 No description available WB:WBGene00173332 21ur-8901 No description available WB:WBGene00173333 21ur-14790 Enriched in neurons based on RNA-seq studies. WB:WBGene00173334 21ur-11136 No description available WB:WBGene00173335 21ur-10421 No description available WB:WBGene00173336 21ur-10895 No description available WB:WBGene00173337 21ur-14376 No description available WB:WBGene00173338 21ur-14287 No description available WB:WBGene00173339 21ur-9981 No description available WB:WBGene00173340 21ur-10565 No description available WB:WBGene00173341 21ur-13829 No description available WB:WBGene00173342 21ur-7053 No description available WB:WBGene00173343 21ur-11013 No description available WB:WBGene00173344 21ur-11932 No description available WB:WBGene00173345 21ur-12912 Is affected by lem-2; emr-1; and rnp-6 based on RNA-seq studies. WB:WBGene00173346 21ur-15196 No description available WB:WBGene00173347 21ur-14755 No description available WB:WBGene00173348 21ur-11924 No description available WB:WBGene00173349 21ur-11692 No description available WB:WBGene00173350 21ur-9854 No description available WB:WBGene00173351 21ur-5681 No description available WB:WBGene00173352 21ur-8325 No description available WB:WBGene00173353 21ur-10885 No description available WB:WBGene00173354 21ur-14708 No description available WB:WBGene00173355 21ur-8685 No description available WB:WBGene00173356 21ur-7261 No description available WB:WBGene00173357 21ur-13117 No description available WB:WBGene00173358 21ur-7894 No description available WB:WBGene00173359 21ur-7755 No description available WB:WBGene00173360 21ur-12231 No description available WB:WBGene00173361 21ur-6457 No description available WB:WBGene00173362 21ur-6175 No description available WB:WBGene00173363 21ur-10156 No description available WB:WBGene00173364 21ur-9475 No description available WB:WBGene00173365 21ur-6660 No description available WB:WBGene00173366 21ur-12481 No description available WB:WBGene00173367 21ur-15169 No description available WB:WBGene00173368 21ur-7183 No description available WB:WBGene00173369 21ur-15390 No description available WB:WBGene00173370 21ur-9989 No description available WB:WBGene00173371 21ur-12804 No description available WB:WBGene00173372 21ur-9894 No description available WB:WBGene00173373 21ur-10176 No description available WB:WBGene00173374 21ur-9881 No description available WB:WBGene00173375 21ur-9310 No description available WB:WBGene00173376 21ur-11313 No description available WB:WBGene00173377 21ur-7284 No description available WB:WBGene00173378 21ur-13952 Is affected by unc-70 and set-2 based on RNA-seq studies. WB:WBGene00173379 21ur-6805 No description available WB:WBGene00173380 21ur-10357 No description available WB:WBGene00173381 21ur-11376 No description available WB:WBGene00173382 21ur-15352 No description available WB:WBGene00173383 21ur-7779 No description available WB:WBGene00173384 21ur-14106 Is affected by set-2 based on RNA-seq studies. WB:WBGene00173385 21ur-12869 No description available WB:WBGene00173386 21ur-8721 No description available WB:WBGene00173387 21ur-9810 No description available WB:WBGene00173388 21ur-10766 No description available WB:WBGene00173389 21ur-12463 No description available WB:WBGene00173390 21ur-7263 No description available WB:WBGene00173391 21ur-8442 No description available WB:WBGene00173392 21ur-6553 No description available WB:WBGene00173393 21ur-11647 No description available WB:WBGene00173394 21ur-8115 No description available WB:WBGene00173395 21ur-12588 No description available WB:WBGene00173396 21ur-14504 No description available WB:WBGene00173397 21ur-11996 No description available WB:WBGene00173398 21ur-10752 No description available WB:WBGene00173399 21ur-10607 No description available WB:WBGene00173400 21ur-8473 No description available WB:WBGene00173401 21ur-6441 No description available WB:WBGene00173402 21ur-6413 No description available WB:WBGene00173403 21ur-14245 No description available WB:WBGene00173404 21ur-14980 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00173405 21ur-10029 Enriched in neurons based on RNA-seq studies. WB:WBGene00173406 21ur-8775 No description available WB:WBGene00173407 21ur-10144 No description available WB:WBGene00173408 21ur-5946 No description available WB:WBGene00173409 21ur-8974 No description available WB:WBGene00173410 21ur-13490 No description available WB:WBGene00173411 21ur-13426 No description available WB:WBGene00173412 21ur-14640 No description available WB:WBGene00173413 21ur-8609 No description available WB:WBGene00173414 21ur-13288 Enriched in AFD based on RNA-seq studies. Is affected by rnp-6 and cpl-1 based on RNA-seq studies. WB:WBGene00173415 21ur-15702 No description available WB:WBGene00173416 21ur-13797 No description available WB:WBGene00173417 21ur-11729 Is affected by hmg-3 and spt-16 based on RNA-seq studies. WB:WBGene00173418 21ur-12449 No description available WB:WBGene00173419 21ur-6956 Enriched in neurons based on RNA-seq studies. WB:WBGene00173420 21ur-9898 No description available WB:WBGene00173421 21ur-5922 No description available WB:WBGene00173422 21ur-12459 No description available WB:WBGene00173423 21ur-9961 Enriched in neurons based on RNA-seq studies. WB:WBGene00173424 21ur-8537 No description available WB:WBGene00173425 21ur-12519 No description available WB:WBGene00173426 21ur-13556 No description available WB:WBGene00173427 21ur-11743 No description available WB:WBGene00173428 21ur-14067 No description available WB:WBGene00173429 21ur-12267 No description available WB:WBGene00173430 21ur-14561 No description available WB:WBGene00173431 21ur-8304 No description available WB:WBGene00173432 21ur-13768 No description available WB:WBGene00173433 21ur-9173 No description available WB:WBGene00173434 21ur-10857 No description available WB:WBGene00173435 21ur-11464 No description available WB:WBGene00173436 21ur-10663 No description available WB:WBGene00173437 21ur-8255 No description available WB:WBGene00173438 21ur-7151 No description available WB:WBGene00173439 21ur-7098 No description available WB:WBGene00173440 21ur-15106 No description available WB:WBGene00173441 21ur-6949 No description available WB:WBGene00173442 21ur-8906 No description available WB:WBGene00173443 21ur-9212 No description available WB:WBGene00173444 21ur-9068 No description available WB:WBGene00173445 21ur-8281 No description available WB:WBGene00173446 21ur-9431 No description available WB:WBGene00173447 21ur-12495 No description available WB:WBGene00173448 21ur-12682 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00173449 21ur-13955 No description available WB:WBGene00173450 21ur-8635 No description available WB:WBGene00173451 21ur-10745 No description available WB:WBGene00173452 21ur-11872 No description available WB:WBGene00173453 21ur-13785 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00173454 21ur-15677 No description available WB:WBGene00173455 21ur-14384 No description available WB:WBGene00173456 21ur-10234 No description available WB:WBGene00173457 21ur-7771 No description available WB:WBGene00173458 21ur-13130 No description available WB:WBGene00173459 21ur-7307 No description available WB:WBGene00173460 21ur-6133 No description available WB:WBGene00173461 21ur-8742 Is affected by set-2 based on RNA-seq studies. WB:WBGene00173462 21ur-9016 Enriched in neurons based on RNA-seq studies. WB:WBGene00173463 21ur-6106 No description available WB:WBGene00173464 21ur-6306 No description available WB:WBGene00173465 21ur-13162 No description available WB:WBGene00173466 21ur-9991 No description available WB:WBGene00173467 21ur-12121 No description available WB:WBGene00173468 21ur-13445 Enriched in neurons based on RNA-seq studies. WB:WBGene00173469 21ur-6532 No description available WB:WBGene00173470 21ur-14472 No description available WB:WBGene00173471 21ur-12627 No description available WB:WBGene00173472 21ur-11947 No description available WB:WBGene00173473 21ur-13171 No description available WB:WBGene00173474 21ur-15582 No description available WB:WBGene00173475 21ur-6832 No description available WB:WBGene00173476 21ur-11484 No description available WB:WBGene00173477 21ur-9725 No description available WB:WBGene00173478 21ur-10478 Enriched in neurons based on RNA-seq studies. WB:WBGene00173480 21ur-7465 No description available WB:WBGene00173481 21ur-5645 No description available WB:WBGene00173482 21ur-9618 No description available WB:WBGene00173483 21ur-7026 No description available WB:WBGene00173484 21ur-10167 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00173485 21ur-13166 No description available WB:WBGene00173486 21ur-11101 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00173487 21ur-7710 No description available WB:WBGene00173488 21ur-6884 No description available WB:WBGene00173489 21ur-9227 No description available WB:WBGene00173490 21ur-10085 No description available WB:WBGene00173491 21ur-6926 No description available WB:WBGene00173492 21ur-9575 No description available WB:WBGene00173493 21ur-7548 No description available WB:WBGene00173494 21ur-9409 No description available WB:WBGene00173495 21ur-15290 No description available WB:WBGene00173496 21ur-8206 No description available WB:WBGene00173497 21ur-15685 No description available WB:WBGene00173498 21ur-11188 No description available WB:WBGene00173499 21ur-9736 No description available WB:WBGene00173500 21ur-8526 No description available WB:WBGene00173501 21ur-11329 No description available WB:WBGene00173502 21ur-11586 No description available WB:WBGene00173503 21ur-11155 No description available WB:WBGene00173504 21ur-7019 No description available WB:WBGene00173505 21ur-15575 Is affected by several genes including set-2; let-418; and smn-1 based on RNA-seq studies. WB:WBGene00173506 21ur-9879 No description available WB:WBGene00173507 21ur-9246 No description available WB:WBGene00173508 21ur-14916 Is affected by hmg-3 and set-2 based on RNA-seq studies. WB:WBGene00173509 21ur-15476 No description available WB:WBGene00173510 21ur-15087 No description available WB:WBGene00173511 21ur-9423 No description available WB:WBGene00173512 21ur-12188 No description available WB:WBGene00173513 21ur-7470 No description available WB:WBGene00173514 21ur-13862 No description available WB:WBGene00173515 21ur-11346 No description available WB:WBGene00173516 21ur-14736 No description available WB:WBGene00173517 21ur-9055 No description available WB:WBGene00173518 21ur-8734 No description available WB:WBGene00173519 21ur-11171 No description available WB:WBGene00173520 21ur-10870 No description available WB:WBGene00173521 21ur-12542 No description available WB:WBGene00173522 21ur-14977 No description available WB:WBGene00173523 21ur-7061 No description available WB:WBGene00173524 21ur-11841 No description available WB:WBGene00173525 21ur-6228 No description available WB:WBGene00173526 21ur-13279 No description available WB:WBGene00173527 21ur-6978 No description available WB:WBGene00173528 21ur-8224 Enriched in neurons based on RNA-seq studies. WB:WBGene00173529 21ur-7079 No description available WB:WBGene00173530 21ur-12896 No description available WB:WBGene00173531 21ur-13481 No description available WB:WBGene00173532 21ur-12016 No description available WB:WBGene00173533 21ur-11971 No description available WB:WBGene00173534 21ur-14956 No description available WB:WBGene00173535 21ur-8007 No description available WB:WBGene00173536 21ur-6559 No description available WB:WBGene00173537 21ur-14396 No description available WB:WBGene00173538 21ur-13820 No description available WB:WBGene00173539 21ur-5459 No description available WB:WBGene00173540 21ur-9331 No description available WB:WBGene00173541 21ur-6251 No description available WB:WBGene00173542 21ur-7915 No description available WB:WBGene00173543 21ur-15220 No description available WB:WBGene00173544 21ur-8862 No description available WB:WBGene00173545 21ur-13017 Enriched in neurons based on RNA-seq studies. WB:WBGene00173546 21ur-11411 No description available WB:WBGene00173547 21ur-10527 No description available WB:WBGene00173548 21ur-9848 No description available WB:WBGene00173550 21ur-10059 No description available WB:WBGene00173551 21ur-12984 No description available WB:WBGene00173552 21ur-15557 No description available WB:WBGene00173553 21ur-14929 No description available WB:WBGene00173554 21ur-11904 No description available WB:WBGene00173555 21ur-12501 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00173556 21ur-9047 No description available WB:WBGene00173557 21ur-12229 No description available WB:WBGene00173558 21ur-13065 No description available WB:WBGene00173559 21ur-7842 No description available WB:WBGene00173560 21ur-15550 No description available WB:WBGene00173561 21ur-14479 No description available WB:WBGene00173562 21ur-6848 No description available WB:WBGene00173563 21ur-9169 No description available WB:WBGene00173564 21ur-12095 No description available WB:WBGene00173565 21ur-9186 No description available WB:WBGene00173566 21ur-7748 No description available WB:WBGene00173567 21ur-6985 No description available WB:WBGene00173568 21ur-11815 Is affected by rnp-6 based on RNA-seq studies. WB:WBGene00173569 21ur-13439 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00173570 21ur-7666 No description available WB:WBGene00173571 21ur-9257 No description available WB:WBGene00173572 21ur-12665 No description available WB:WBGene00173573 21ur-13471 No description available WB:WBGene00173574 21ur-9856 No description available WB:WBGene00173575 21ur-11386 No description available WB:WBGene00173576 21ur-11836 No description available WB:WBGene00173577 21ur-8421 No description available WB:WBGene00173578 21ur-15414 No description available WB:WBGene00173579 21ur-6331 No description available WB:WBGene00173580 21ur-8728 No description available WB:WBGene00173581 21ur-8562 No description available WB:WBGene00173582 21ur-9971 No description available WB:WBGene00173583 21ur-10775 No description available WB:WBGene00173584 21ur-14990 No description available WB:WBGene00173585 21ur-14551 No description available WB:WBGene00173586 21ur-14365 Is affected by eat-2 based on microarray studies. WB:WBGene00173587 21ur-13833 No description available WB:WBGene00173588 21ur-13757 Is affected by ins-11 based on RNA-seq studies. WB:WBGene00173589 21ur-5494 No description available WB:WBGene00173590 21ur-13873 No description available WB:WBGene00173591 21ur-12404 No description available WB:WBGene00173592 21ur-13448 No description available WB:WBGene00173593 21ur-6775 No description available WB:WBGene00173594 21ur-12103 No description available WB:WBGene00173595 21ur-6470 No description available WB:WBGene00173596 21ur-7247 No description available WB:WBGene00173597 21ur-8797 No description available WB:WBGene00173598 21ur-11159 No description available WB:WBGene00173599 21ur-13048 No description available WB:WBGene00173600 21ur-6490 No description available WB:WBGene00173601 21ur-11938 No description available WB:WBGene00173602 21ur-14538 No description available WB:WBGene00173603 21ur-6238 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00173604 21ur-12470 No description available WB:WBGene00173605 21ur-12879 No description available WB:WBGene00173606 21ur-14178 No description available WB:WBGene00173607 21ur-13391 No description available WB:WBGene00173608 21ur-5766 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00173609 21ur-12358 No description available WB:WBGene00173610 21ur-5518 No description available WB:WBGene00173611 21ur-13365 No description available WB:WBGene00173612 21ur-9176 Enriched in neurons based on RNA-seq studies. WB:WBGene00173613 21ur-7048 No description available WB:WBGene00173614 21ur-7499 No description available WB:WBGene00173615 21ur-12311 Enriched in neurons based on RNA-seq studies. WB:WBGene00173616 21ur-10356 No description available WB:WBGene00173617 21ur-14494 No description available WB:WBGene00173618 21ur-12994 No description available WB:WBGene00173619 21ur-6760 No description available WB:WBGene00173620 21ur-10992 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00173621 21ur-7769 No description available WB:WBGene00173622 21ur-11295 No description available WB:WBGene00173623 21ur-15628 No description available WB:WBGene00173624 21ur-13156 Enriched in neurons based on RNA-seq studies. WB:WBGene00173625 21ur-14270 No description available WB:WBGene00173626 21ur-7675 No description available WB:WBGene00173627 21ur-5838 No description available WB:WBGene00173628 21ur-13319 No description available WB:WBGene00173629 21ur-14306 No description available WB:WBGene00173630 21ur-7877 No description available WB:WBGene00173631 21ur-8000 No description available WB:WBGene00173632 21ur-15265 No description available WB:WBGene00173633 21ur-9162 No description available WB:WBGene00173634 21ur-8144 Enriched in neurons based on RNA-seq studies. WB:WBGene00173635 21ur-13316 Enriched in neurons based on RNA-seq studies. WB:WBGene00173636 21ur-14025 Enriched in neurons based on RNA-seq studies. WB:WBGene00173637 21ur-10052 No description available WB:WBGene00173638 21ur-12415 No description available WB:WBGene00173639 21ur-14216 No description available WB:WBGene00173640 21ur-12220 No description available WB:WBGene00173641 21ur-9683 No description available WB:WBGene00173642 21ur-10096 No description available WB:WBGene00173643 21ur-6756 No description available WB:WBGene00173644 21ur-12882 No description available WB:WBGene00173645 21ur-12532 No description available WB:WBGene00173646 21ur-12567 No description available WB:WBGene00173647 21ur-5572 No description available WB:WBGene00173648 21ur-15164 No description available WB:WBGene00173649 21ur-14465 No description available WB:WBGene00173650 21ur-10106 No description available WB:WBGene00173651 21ur-12139 No description available WB:WBGene00173652 21ur-8450 No description available WB:WBGene00173653 21ur-11677 No description available WB:WBGene00173654 21ur-14018 No description available WB:WBGene00173655 21ur-12845 No description available WB:WBGene00173656 21ur-13335 No description available WB:WBGene00173657 21ur-11247 Is affected by daf-2 based on microarray studies. WB:WBGene00173658 21ur-6325 No description available WB:WBGene00173659 21ur-13665 Enriched in neurons based on RNA-seq studies. WB:WBGene00173660 21ur-14608 No description available WB:WBGene00173661 21ur-9826 No description available WB:WBGene00173662 21ur-11086 No description available WB:WBGene00173663 21ur-9869 No description available WB:WBGene00173664 21ur-14289 Enriched in neurons based on RNA-seq studies. WB:WBGene00173665 21ur-12335 No description available WB:WBGene00173666 21ur-13214 No description available WB:WBGene00173667 21ur-15594 No description available WB:WBGene00173668 21ur-9954 No description available WB:WBGene00173669 21ur-13762 No description available WB:WBGene00173670 21ur-13733 No description available WB:WBGene00173671 21ur-10223 No description available WB:WBGene00173672 21ur-13257 No description available WB:WBGene00173673 21ur-8838 No description available WB:WBGene00173674 21ur-15399 No description available WB:WBGene00173675 21ur-6110 No description available WB:WBGene00173676 21ur-5954 No description available WB:WBGene00173677 21ur-14778 No description available WB:WBGene00173678 21ur-9817 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00173679 21ur-8636 No description available WB:WBGene00173680 21ur-5825 No description available WB:WBGene00173681 21ur-15427 Enriched in neurons based on RNA-seq studies. WB:WBGene00173682 21ur-12107 No description available WB:WBGene00173683 21ur-14029 Is affected by lem-2; emr-1; and etr-1 based on RNA-seq studies. WB:WBGene00173684 21ur-11524 No description available WB:WBGene00173685 21ur-9236 No description available WB:WBGene00173686 21ur-5632 No description available WB:WBGene00173687 21ur-7867 No description available WB:WBGene00173688 21ur-12008 No description available WB:WBGene00173689 21ur-14430 No description available WB:WBGene00173690 21ur-12340 No description available WB:WBGene00173691 21ur-7415 Enriched in neurons based on RNA-seq studies. WB:WBGene00173692 21ur-6434 No description available WB:WBGene00173693 21ur-14783 No description available WB:WBGene00173694 21ur-8515 No description available WB:WBGene00173695 21ur-11557 No description available WB:WBGene00173696 21ur-7963 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00173697 21ur-10316 No description available WB:WBGene00173698 21ur-15589 Enriched in neurons based on RNA-seq studies. WB:WBGene00173699 21ur-14425 No description available WB:WBGene00173700 21ur-6915 No description available WB:WBGene00173701 21ur-12176 No description available WB:WBGene00173702 21ur-6079 No description available WB:WBGene00173703 21ur-13007 No description available WB:WBGene00173704 21ur-9188 No description available WB:WBGene00173705 21ur-6667 No description available WB:WBGene00173706 21ur-11858 No description available WB:WBGene00173707 21ur-13222 No description available WB:WBGene00173708 21ur-6790 No description available WB:WBGene00173709 21ur-6552 No description available WB:WBGene00173710 21ur-15562 No description available WB:WBGene00173711 21ur-6208 No description available WB:WBGene00173712 21ur-12064 Enriched in neurons based on RNA-seq studies. WB:WBGene00173713 21ur-11142 No description available WB:WBGene00173714 21ur-14086 No description available WB:WBGene00173715 21ur-14031 Enriched in neurons based on RNA-seq studies. Is affected by ikb-1 based on RNA-seq studies. WB:WBGene00173716 21ur-11469 No description available WB:WBGene00173717 21ur-7287 No description available WB:WBGene00173718 21ur-6783 No description available WB:WBGene00173719 21ur-10411 No description available WB:WBGene00173720 21ur-11052 No description available WB:WBGene00173721 21ur-12236 Is affected by set-2 based on RNA-seq studies. WB:WBGene00173722 21ur-6263 No description available WB:WBGene00173723 21ur-14137 No description available WB:WBGene00173724 21ur-12255 No description available WB:WBGene00173725 21ur-12811 No description available WB:WBGene00173726 21ur-10066 No description available WB:WBGene00173727 21ur-6322 No description available WB:WBGene00173728 21ur-7337 No description available WB:WBGene00173729 21ur-7170 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00173730 21ur-10714 No description available WB:WBGene00173731 21ur-10833 No description available WB:WBGene00173732 21ur-13098 No description available WB:WBGene00173733 21ur-6681 No description available WB:WBGene00173734 21ur-12725 No description available WB:WBGene00173735 21ur-12790 No description available WB:WBGene00173736 21ur-13206 No description available WB:WBGene00173737 21ur-13465 No description available WB:WBGene00173738 21ur-15171 No description available WB:WBGene00173739 21ur-6819 No description available WB:WBGene00173740 21ur-12202 No description available WB:WBGene00173741 21ur-5604 No description available WB:WBGene00173742 21ur-11787 No description available WB:WBGene00173743 21ur-14322 No description available WB:WBGene00173744 21ur-6005 No description available WB:WBGene00173745 21ur-9116 No description available WB:WBGene00173746 21ur-6815 No description available WB:WBGene00173747 21ur-8628 No description available WB:WBGene00173748 21ur-9107 No description available WB:WBGene00173749 21ur-10034 No description available WB:WBGene00173750 21ur-12093 No description available WB:WBGene00173751 21ur-13565 No description available WB:WBGene00173752 21ur-8792 No description available WB:WBGene00173753 21ur-10125 No description available WB:WBGene00173754 21ur-10724 No description available WB:WBGene00173755 21ur-12293 No description available WB:WBGene00173756 21ur-13300 No description available WB:WBGene00173757 21ur-13219 No description available WB:WBGene00173758 21ur-6703 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00173759 21ur-10791 No description available WB:WBGene00173760 21ur-8805 No description available WB:WBGene00173761 21ur-11683 No description available WB:WBGene00173762 21ur-13841 No description available WB:WBGene00173763 21ur-5608 Is affected by daf-2 based on microarray studies. WB:WBGene00173764 21ur-14209 No description available WB:WBGene00173765 21ur-6461 No description available WB:WBGene00173766 21ur-10725 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00173767 21ur-8419 No description available WB:WBGene00173768 21ur-10460 No description available WB:WBGene00173769 21ur-9205 No description available WB:WBGene00173770 21ur-13869 No description available WB:WBGene00173771 21ur-6544 No description available WB:WBGene00173772 21ur-6988 No description available WB:WBGene00173773 21ur-15472 No description available WB:WBGene00173774 21ur-8301 No description available WB:WBGene00173775 21ur-7234 No description available WB:WBGene00173776 21ur-6808 Enriched in neurons based on RNA-seq studies. WB:WBGene00173777 21ur-9438 Enriched in neurons based on RNA-seq studies. WB:WBGene00173778 21ur-9441 No description available WB:WBGene00173779 21ur-5589 Is affected by daf-2 based on microarray studies. WB:WBGene00173780 21ur-5759 No description available WB:WBGene00173781 21ur-12697 No description available WB:WBGene00173782 21ur-7136 No description available WB:WBGene00173783 21ur-10559 No description available WB:WBGene00173784 21ur-15680 No description available WB:WBGene00173785 21ur-6130 No description available WB:WBGene00173786 21ur-10493 No description available WB:WBGene00173787 21ur-9347 No description available WB:WBGene00173788 21ur-10110 No description available WB:WBGene00173789 21ur-13394 Enriched in neurons based on RNA-seq studies. WB:WBGene00173790 21ur-15055 No description available WB:WBGene00173791 21ur-14372 No description available WB:WBGene00173792 21ur-7891 No description available WB:WBGene00173793 21ur-7309 No description available WB:WBGene00173794 21ur-13203 No description available WB:WBGene00173795 21ur-11293 No description available WB:WBGene00173796 21ur-13992 No description available WB:WBGene00173797 21ur-6346 No description available WB:WBGene00173798 21ur-10540 No description available WB:WBGene00173799 21ur-10966 No description available WB:WBGene00173800 21ur-9323 No description available WB:WBGene00173801 21ur-7766 No description available WB:WBGene00173802 21ur-10148 No description available WB:WBGene00173803 21ur-11160 No description available WB:WBGene00173804 21ur-10549 No description available WB:WBGene00173805 21ur-7239 No description available WB:WBGene00173806 21ur-15410 No description available WB:WBGene00173807 21ur-14382 No description available WB:WBGene00173808 21ur-12222 No description available WB:WBGene00173809 21ur-15084 No description available WB:WBGene00173810 21ur-15050 No description available WB:WBGene00173811 21ur-8533 No description available WB:WBGene00173812 21ur-8368 No description available WB:WBGene00173813 21ur-7012 No description available WB:WBGene00173814 21ur-12778 No description available WB:WBGene00173815 21ur-10396 No description available WB:WBGene00173816 21ur-13546 No description available WB:WBGene00173817 21ur-14541 No description available WB:WBGene00173818 21ur-10209 No description available WB:WBGene00173819 21ur-10070 No description available WB:WBGene00173820 21ur-7445 No description available WB:WBGene00173821 21ur-12372 No description available WB:WBGene00173822 21ur-14809 No description available WB:WBGene00173823 21ur-11593 No description available WB:WBGene00173824 21ur-13024 No description available WB:WBGene00173825 21ur-15564 No description available WB:WBGene00173826 21ur-14333 No description available WB:WBGene00173827 21ur-13921 No description available WB:WBGene00173828 21ur-9945 No description available WB:WBGene00173829 21ur-10852 No description available WB:WBGene00173830 21ur-11577 No description available WB:WBGene00173831 21ur-14765 No description available WB:WBGene00173832 21ur-11596 No description available WB:WBGene00173833 21ur-13979 No description available WB:WBGene00173834 21ur-6924 No description available WB:WBGene00173835 21ur-10076 No description available WB:WBGene00173836 21ur-11773 No description available WB:WBGene00173837 21ur-9521 No description available WB:WBGene00173838 21ur-14193 No description available WB:WBGene00173839 21ur-13908 No description available WB:WBGene00173840 21ur-12243 No description available WB:WBGene00173841 21ur-14254 No description available WB:WBGene00173842 21ur-11918 No description available WB:WBGene00173843 21ur-14293 No description available WB:WBGene00173844 21ur-6082 No description available WB:WBGene00173845 21ur-10797 Enriched in neurons based on RNA-seq studies. WB:WBGene00173846 21ur-8148 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00173847 21ur-9966 Enriched in neurons based on RNA-seq studies. WB:WBGene00173848 21ur-15101 Enriched in neurons based on RNA-seq studies. WB:WBGene00173849 21ur-7274 No description available WB:WBGene00173850 21ur-11748 No description available WB:WBGene00173851 21ur-13935 No description available WB:WBGene00173852 21ur-15322 No description available WB:WBGene00173853 21ur-10898 No description available WB:WBGene00173854 21ur-6573 No description available WB:WBGene00173855 21ur-10941 No description available WB:WBGene00173856 21ur-11127 No description available WB:WBGene00173857 21ur-5698 No description available WB:WBGene00173858 21ur-11427 No description available WB:WBGene00173859 21ur-7384 No description available WB:WBGene00173860 21ur-11806 No description available WB:WBGene00173861 21ur-7380 No description available WB:WBGene00173862 21ur-14097 No description available WB:WBGene00173863 21ur-14277 No description available WB:WBGene00173864 21ur-12274 No description available WB:WBGene00173865 21ur-11612 No description available WB:WBGene00173866 21ur-15435 No description available WB:WBGene00173867 21ur-10598 No description available WB:WBGene00173868 21ur-6045 No description available WB:WBGene00173869 21ur-13488 No description available WB:WBGene00173870 21ur-7925 No description available WB:WBGene00173871 21ur-14352 No description available WB:WBGene00173872 21ur-6850 No description available WB:WBGene00173873 21ur-12539 No description available WB:WBGene00173874 21ur-8156 No description available WB:WBGene00173875 21ur-10140 No description available WB:WBGene00173876 21ur-5968 No description available WB:WBGene00173877 21ur-7440 No description available WB:WBGene00173878 21ur-12781 No description available WB:WBGene00173879 21ur-8387 No description available WB:WBGene00173880 21ur-7198 No description available WB:WBGene00173881 21ur-9022 No description available WB:WBGene00173882 21ur-6095 No description available WB:WBGene00173883 21ur-11357 No description available WB:WBGene00173884 21ur-15586 Enriched in neurons based on RNA-seq studies. WB:WBGene00173885 21ur-5718 No description available WB:WBGene00173886 21ur-11231 No description available WB:WBGene00173887 21ur-6749 No description available WB:WBGene00173888 21ur-6879 No description available WB:WBGene00173889 21ur-7134 No description available WB:WBGene00173890 21ur-7490 No description available WB:WBGene00173891 21ur-10426 No description available WB:WBGene00173892 21ur-12411 No description available WB:WBGene00173893 21ur-14291 No description available WB:WBGene00173894 21ur-6590 No description available WB:WBGene00173895 21ur-11292 No description available WB:WBGene00173896 21ur-5461 No description available WB:WBGene00173897 21ur-5556 No description available WB:WBGene00173898 21ur-9512 No description available WB:WBGene00173899 21ur-15660 No description available WB:WBGene00173900 21ur-8704 No description available WB:WBGene00173901 21ur-15503 No description available WB:WBGene00173902 21ur-6089 No description available WB:WBGene00173903 21ur-14480 No description available WB:WBGene00173904 21ur-7400 Is affected by eat-2 and camt-1 based on microarray and RNA-seq studies. WB:WBGene00173905 21ur-13434 No description available WB:WBGene00173906 21ur-8970 No description available WB:WBGene00173907 21ur-8415 No description available WB:WBGene00173908 21ur-8055 No description available WB:WBGene00173909 21ur-13427 No description available WB:WBGene00173910 21ur-7369 No description available WB:WBGene00173911 21ur-10008 No description available WB:WBGene00173912 21ur-15632 No description available WB:WBGene00173913 21ur-14901 No description available WB:WBGene00173914 21ur-9582 No description available WB:WBGene00173915 21ur-5974 No description available WB:WBGene00173916 21ur-12150 No description available WB:WBGene00173917 21ur-6397 No description available WB:WBGene00173918 21ur-13901 No description available WB:WBGene00173919 21ur-6363 No description available WB:WBGene00173920 21ur-8696 Is affected by damt-1; swsn-9; and etr-1 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00173921 21ur-11724 No description available WB:WBGene00173922 21ur-15311 No description available WB:WBGene00173923 21ur-6479 Enriched in neurons based on RNA-seq studies. WB:WBGene00173924 21ur-12163 No description available WB:WBGene00173925 21ur-9082 No description available WB:WBGene00173926 21ur-6835 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00173927 21ur-11504 No description available WB:WBGene00173928 21ur-11685 No description available WB:WBGene00173929 21ur-12396 No description available WB:WBGene00173930 21ur-12195 No description available WB:WBGene00173931 21ur-10801 No description available WB:WBGene00173932 21ur-9385 No description available WB:WBGene00173933 21ur-11022 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00173934 21ur-14412 No description available WB:WBGene00173935 21ur-10716 No description available WB:WBGene00173936 21ur-13339 No description available WB:WBGene00173937 21ur-7357 No description available WB:WBGene00173938 21ur-10274 No description available WB:WBGene00173939 21ur-11215 No description available WB:WBGene00173940 21ur-7879 No description available WB:WBGene00173941 21ur-5629 No description available WB:WBGene00173942 21ur-9153 No description available WB:WBGene00173943 21ur-9089 No description available WB:WBGene00173944 21ur-11105 No description available WB:WBGene00173945 21ur-15133 No description available WB:WBGene00173946 21ur-15227 No description available WB:WBGene00173947 21ur-7174 No description available WB:WBGene00173948 21ur-11181 No description available WB:WBGene00173949 21ur-10404 No description available WB:WBGene00173950 21ur-11982 No description available WB:WBGene00173951 21ur-7280 No description available WB:WBGene00173952 21ur-9379 No description available WB:WBGene00173953 21ur-15034 No description available WB:WBGene00173954 21ur-13522 No description available WB:WBGene00173955 21ur-8928 No description available WB:WBGene00173956 21ur-12901 No description available WB:WBGene00173957 21ur-15523 Is affected by ins-11 based on RNA-seq studies. WB:WBGene00173958 21ur-15160 No description available WB:WBGene00173959 21ur-10462 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00173960 21ur-7036 No description available WB:WBGene00173961 21ur-14691 No description available WB:WBGene00173962 21ur-14033 No description available WB:WBGene00173963 21ur-13059 No description available WB:WBGene00173964 21ur-15250 No description available WB:WBGene00173965 21ur-15449 No description available WB:WBGene00173966 21ur-11630 No description available WB:WBGene00173967 21ur-15268 No description available WB:WBGene00173968 21ur-13614 No description available WB:WBGene00173969 21ur-10763 No description available WB:WBGene00173970 21ur-13972 No description available WB:WBGene00173971 21ur-8044 No description available WB:WBGene00173972 21ur-5983 No description available WB:WBGene00173973 21ur-6801 No description available WB:WBGene00173974 21ur-6951 No description available WB:WBGene00173975 21ur-15481 No description available WB:WBGene00173976 21ur-13747 No description available WB:WBGene00173977 21ur-11715 No description available WB:WBGene00173978 21ur-8171 No description available WB:WBGene00173979 21ur-6857 No description available WB:WBGene00173980 21ur-15062 No description available WB:WBGene00173981 21ur-14972 No description available WB:WBGene00173982 21ur-9602 No description available WB:WBGene00173983 21ur-11436 No description available WB:WBGene00173984 21ur-13504 Enriched in neurons based on RNA-seq studies. WB:WBGene00173985 21ur-14455 No description available WB:WBGene00173986 21ur-6586 No description available WB:WBGene00173987 21ur-11911 No description available WB:WBGene00173988 21ur-12968 No description available WB:WBGene00173989 21ur-5672 No description available WB:WBGene00173990 21ur-7326 No description available WB:WBGene00173991 21ur-10062 No description available WB:WBGene00173992 21ur-6255 No description available WB:WBGene00173993 21ur-7101 No description available WB:WBGene00173994 21ur-5622 No description available WB:WBGene00173995 21ur-15143 No description available WB:WBGene00173996 21ur-5537 No description available WB:WBGene00173997 21ur-11545 No description available WB:WBGene00173998 21ur-14672 No description available WB:WBGene00173999 21ur-11451 No description available WB:WBGene00174000 21ur-14367 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00174001 21ur-11147 No description available WB:WBGene00174002 21ur-6611 No description available WB:WBGene00174003 21ur-6999 No description available WB:WBGene00174004 21ur-13816 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00174005 21ur-14845 No description available WB:WBGene00174006 21ur-10824 No description available WB:WBGene00174007 21ur-9001 No description available WB:WBGene00174008 21ur-12906 No description available WB:WBGene00174009 21ur-10265 No description available WB:WBGene00174010 21ur-9517 No description available WB:WBGene00174011 21ur-6221 No description available WB:WBGene00174012 21ur-13420 No description available WB:WBGene00174013 21ur-7522 No description available WB:WBGene00174014 21ur-14054 No description available WB:WBGene00174015 21ur-7741 No description available WB:WBGene00174016 21ur-7844 No description available WB:WBGene00174017 21ur-15175 No description available WB:WBGene00174018 21ur-13674 No description available WB:WBGene00174019 21ur-9427 No description available WB:WBGene00174020 21ur-10486 No description available WB:WBGene00174021 21ur-5639 No description available WB:WBGene00174022 21ur-6967 No description available WB:WBGene00174023 21ur-15670 No description available WB:WBGene00174024 21ur-9142 No description available WB:WBGene00174025 21ur-10864 No description available WB:WBGene00174026 21ur-15093 No description available WB:WBGene00174027 21ur-14651 No description available WB:WBGene00174028 21ur-6048 No description available WB:WBGene00174029 21ur-8955 No description available WB:WBGene00174030 21ur-11853 No description available WB:WBGene00174031 21ur-10212 No description available WB:WBGene00174032 21ur-15691 No description available WB:WBGene00174033 21ur-11420 No description available WB:WBGene00174034 21ur-5902 No description available WB:WBGene00174035 21ur-5580 No description available WB:WBGene00174036 21ur-13512 No description available WB:WBGene00174037 21ur-10514 No description available WB:WBGene00174038 21ur-8647 No description available WB:WBGene00174039 21ur-6597 No description available WB:WBGene00174040 21ur-6448 No description available WB:WBGene00174041 21ur-9611 No description available WB:WBGene00174042 21ur-13715 No description available WB:WBGene00174043 21ur-15036 No description available WB:WBGene00174044 21ur-11396 No description available WB:WBGene00174045 21ur-10365 No description available WB:WBGene00174046 21ur-9232 No description available WB:WBGene00174047 21ur-7729 No description available WB:WBGene00174048 21ur-12824 No description available WB:WBGene00174049 21ur-15114 No description available WB:WBGene00174050 21ur-6162 No description available WB:WBGene00174051 21ur-12585 No description available WB:WBGene00174052 21ur-7419 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00174053 21ur-13102 No description available WB:WBGene00174054 21ur-14780 No description available WB:WBGene00174055 21ur-5764 No description available WB:WBGene00174056 21ur-8944 Enriched in neurons based on RNA-seq studies. WB:WBGene00174057 21ur-8578 No description available WB:WBGene00174058 21ur-7706 No description available WB:WBGene00174059 21ur-11302 No description available WB:WBGene00174060 21ur-10950 No description available WB:WBGene00174061 21ur-8550 No description available WB:WBGene00174062 21ur-8918 No description available WB:WBGene00174063 21ur-10185 No description available WB:WBGene00174064 21ur-10339 No description available WB:WBGene00174065 21ur-12377 No description available WB:WBGene00174066 21ur-13594 No description available WB:WBGene00174067 21ur-6059 No description available WB:WBGene00174068 21ur-13119 No description available WB:WBGene00174069 21ur-14632 No description available WB:WBGene00174070 21ur-8895 No description available WB:WBGene00174071 21ur-8026 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00174072 21ur-6090 Enriched in neurons based on RNA-seq studies. WB:WBGene00174073 21ur-12632 No description available WB:WBGene00174074 21ur-8829 No description available WB:WBGene00174075 21ur-11790 No description available WB:WBGene00174076 21ur-15285 No description available WB:WBGene00174077 21ur-12420 No description available WB:WBGene00174078 21ur-13880 No description available WB:WBGene00174079 21ur-13639 No description available WB:WBGene00174080 21ur-13159 No description available WB:WBGene00174081 21ur-13949 No description available WB:WBGene00174082 21ur-6464 No description available WB:WBGene00174083 21ur-10320 No description available WB:WBGene00174084 21ur-13378 Enriched in neurons based on RNA-seq studies. WB:WBGene00174085 21ur-7553 No description available WB:WBGene00174086 21ur-8337 No description available WB:WBGene00174087 21ur-10658 No description available WB:WBGene00174088 21ur-14524 No description available WB:WBGene00174089 21ur-11492 No description available WB:WBGene00174090 21ur-9590 No description available WB:WBGene00174091 21ur-11550 No description available WB:WBGene00174092 21ur-14599 No description available WB:WBGene00174093 21ur-6680 Is affected by daf-2 based on microarray studies. WB:WBGene00174094 21ur-14851 No description available WB:WBGene00174095 21ur-10092 No description available WB:WBGene00174096 21ur-10327 No description available WB:WBGene00174097 21ur-13625 No description available WB:WBGene00174098 21ur-11201 No description available WB:WBGene00174099 21ur-6216 No description available WB:WBGene00174100 21ur-5801 No description available WB:WBGene00174101 21ur-12607 No description available WB:WBGene00174102 21ur-6277 No description available WB:WBGene00174103 21ur-10475 No description available WB:WBGene00174104 21ur-5894 No description available WB:WBGene00174105 21ur-15430 No description available WB:WBGene00174106 21ur-12146 No description available WB:WBGene00174107 21ur-6292 No description available WB:WBGene00174108 21ur-9795 No description available WB:WBGene00174109 21ur-5933 No description available WB:WBGene00174110 21ur-8167 No description available WB:WBGene00174111 21ur-13189 No description available WB:WBGene00174112 21ur-5676 No description available WB:WBGene00174113 21ur-7117 No description available WB:WBGene00174114 21ur-12756 No description available WB:WBGene00174115 21ur-8459 No description available WB:WBGene00174116 21ur-7874 No description available WB:WBGene00174117 21ur-7947 No description available WB:WBGene00174118 21ur-6020 No description available WB:WBGene00174119 21ur-7075 No description available WB:WBGene00174120 21ur-6030 No description available WB:WBGene00174121 21ur-12841 No description available WB:WBGene00174122 21ur-7731 No description available WB:WBGene00174123 21ur-11447 No description available WB:WBGene00174124 21ur-14221 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174125 21ur-6473 No description available WB:WBGene00174126 21ur-10504 No description available WB:WBGene00174127 21ur-13259 No description available WB:WBGene00174128 21ur-8604 No description available WB:WBGene00174129 21ur-10166 No description available WB:WBGene00174130 21ur-14643 No description available WB:WBGene00174131 21ur-7782 No description available WB:WBGene00174132 21ur-6184 No description available WB:WBGene00174133 21ur-14453 No description available WB:WBGene00174134 21ur-8093 No description available WB:WBGene00174135 21ur-7688 No description available WB:WBGene00174136 21ur-12562 Is affected by daf-2 based on microarray studies. WB:WBGene00174137 21ur-10115 Enriched in AFD based on RNA-seq studies. WB:WBGene00174138 21ur-11807 No description available WB:WBGene00174139 21ur-8348 No description available WB:WBGene00174140 21ur-14582 No description available WB:WBGene00174141 21ur-11934 Enriched in neurons based on RNA-seq studies. WB:WBGene00174142 21ur-8486 No description available WB:WBGene00174143 21ur-6685 No description available WB:WBGene00174144 21ur-7212 No description available WB:WBGene00174145 21ur-6626 No description available WB:WBGene00174146 21ur-13180 No description available WB:WBGene00174147 21ur-15388 No description available WB:WBGene00174148 21ur-9717 No description available WB:WBGene00174149 21ur-10601 No description available WB:WBGene00174150 21ur-12987 No description available WB:WBGene00174151 21ur-7367 No description available WB:WBGene00174152 21ur-10132 No description available WB:WBGene00174153 21ur-12304 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00174154 21ur-15339 Enriched in neurons based on RNA-seq studies. WB:WBGene00174155 21ur-13268 No description available WB:WBGene00174156 21ur-9113 No description available WB:WBGene00174157 21ur-7726 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00174158 21ur-6411 No description available WB:WBGene00174159 21ur-15649 No description available WB:WBGene00174160 21ur-10817 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00174161 21ur-11567 No description available WB:WBGene00174162 21ur-13630 No description available WB:WBGene00174163 21ur-11031 No description available WB:WBGene00174164 21ur-11863 No description available WB:WBGene00174165 21ur-13582 No description available WB:WBGene00174166 21ur-7889 No description available WB:WBGene00174167 21ur-8568 No description available WB:WBGene00174168 21ur-13960 No description available WB:WBGene00174169 21ur-8271 No description available WB:WBGene00174170 21ur-15208 No description available WB:WBGene00174171 21ur-13681 No description available WB:WBGene00174172 21ur-12437 No description available WB:WBGene00174173 21ur-10024 No description available WB:WBGene00174174 21ur-14591 No description available WB:WBGene00174175 21ur-6766 No description available WB:WBGene00174176 21ur-7164 No description available WB:WBGene00174177 21ur-11753 No description available WB:WBGene00174178 21ur-11281 No description available WB:WBGene00174179 21ur-13853 No description available WB:WBGene00174180 21ur-8820 No description available WB:WBGene00174181 21ur-7898 No description available WB:WBGene00174182 21ur-14111 No description available WB:WBGene00174183 21ur-10202 No description available WB:WBGene00174184 21ur-11264 No description available WB:WBGene00174185 21ur-6116 No description available WB:WBGene00174186 21ur-8292 No description available WB:WBGene00174187 21ur-9245 No description available WB:WBGene00174188 21ur-9790 No description available WB:WBGene00174189 21ur-10225 No description available WB:WBGene00174190 21ur-13946 No description available WB:WBGene00174191 21ur-11781 No description available WB:WBGene00174192 21ur-14087 No description available WB:WBGene00174193 21ur-11600 No description available WB:WBGene00174194 21ur-10642 No description available WB:WBGene00174195 21ur-5505 Enriched in neurons based on RNA-seq studies. WB:WBGene00174196 21ur-8617 No description available WB:WBGene00174197 21ur-9714 No description available WB:WBGene00174198 21ur-11987 No description available WB:WBGene00174199 21ur-12355 No description available WB:WBGene00174200 21ur-15535 No description available WB:WBGene00174201 21ur-12765 No description available WB:WBGene00174202 21ur-15330 No description available WB:WBGene00174203 21ur-13887 No description available WB:WBGene00174204 21ur-14930 No description available WB:WBGene00174205 21ur-13799 No description available WB:WBGene00174206 21ur-5789 Enriched in neurons based on RNA-seq studies. WB:WBGene00174207 21ur-6634 No description available WB:WBGene00174208 21ur-8655 No description available WB:WBGene00174209 21ur-8230 No description available WB:WBGene00174210 21ur-7074 No description available WB:WBGene00174211 21ur-15115 No description available WB:WBGene00174212 21ur-7049 Is affected by set-2 based on RNA-seq studies. WB:WBGene00174213 21ur-13385 No description available WB:WBGene00174214 21ur-14912 No description available WB:WBGene00174215 21ur-6642 No description available WB:WBGene00174216 21ur-11098 No description available WB:WBGene00174217 21ur-11038 No description available WB:WBGene00174218 21ur-14660 No description available WB:WBGene00174219 21ur-9207 Is affected by several genes including atfs-1; hmg-4; and hmg-3 based on RNA-seq studies. WB:WBGene00174220 21ur-6862 No description available WB:WBGene00174221 21ur-9631 No description available WB:WBGene00174222 21ur-9278 No description available WB:WBGene00174223 21ur-5798 No description available WB:WBGene00174224 21ur-6944 No description available WB:WBGene00174225 21ur-10374 No description available WB:WBGene00174226 21ur-9866 No description available WB:WBGene00174227 21ur-11206 No description available WB:WBGene00174228 21ur-9637 No description available WB:WBGene00174229 21ur-14125 No description available WB:WBGene00174230 21ur-6291 No description available WB:WBGene00174231 21ur-10524 No description available WB:WBGene00174232 21ur-8782 No description available WB:WBGene00174233 21ur-7789 No description available WB:WBGene00174234 21ur-8235 No description available WB:WBGene00174235 21ur-5913 No description available WB:WBGene00174236 21ur-10531 No description available WB:WBGene00174237 21ur-6722 No description available WB:WBGene00174238 21ur-11655 No description available WB:WBGene00174239 21ur-13277 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174240 21ur-9482 No description available WB:WBGene00174241 21ur-11018 No description available WB:WBGene00174242 21ur-9709 Enriched in neurons based on RNA-seq studies. WB:WBGene00174243 21ur-8853 No description available WB:WBGene00174244 21ur-11258 No description available WB:WBGene00174245 21ur-14309 No description available WB:WBGene00174246 21ur-9138 No description available WB:WBGene00174247 21ur-10302 No description available WB:WBGene00174248 21ur-8857 No description available WB:WBGene00174249 21ur-12089 No description available WB:WBGene00174250 21ur-13124 No description available WB:WBGene00174251 21ur-15048 No description available WB:WBGene00174252 21ur-13570 No description available WB:WBGene00174253 21ur-9622 No description available WB:WBGene00174254 21ur-6905 No description available WB:WBGene00174255 21ur-8370 No description available WB:WBGene00174256 21ur-9286 No description available WB:WBGene00174257 21ur-5950 Is affected by lem-2; emr-1; and hmg-3 based on RNA-seq studies. WB:WBGene00174258 21ur-14802 No description available WB:WBGene00174259 21ur-7900 No description available WB:WBGene00174260 21ur-10855 No description available WB:WBGene00174261 21ur-13238 No description available WB:WBGene00174262 21ur-11091 No description available WB:WBGene00174263 21ur-13142 No description available WB:WBGene00174264 21ur-15488 No description available WB:WBGene00174265 21ur-5651 No description available WB:WBGene00174266 21ur-13697 No description available WB:WBGene00174267 21ur-7570 No description available WB:WBGene00174268 21ur-9258 No description available WB:WBGene00174269 21ur-5543 No description available WB:WBGene00174270 21ur-6354 Is affected by several genes including hpl-2; set-2; and lem-2 based on RNA-seq studies. WB:WBGene00174271 21ur-12673 No description available WB:WBGene00174272 21ur-7253 No description available WB:WBGene00174273 21ur-13703 No description available WB:WBGene00174274 21ur-7580 No description available WB:WBGene00174275 21ur-14800 No description available WB:WBGene00174276 21ur-8572 No description available WB:WBGene00174277 21ur-6104 No description available WB:WBGene00174278 21ur-13640 No description available WB:WBGene00174279 21ur-10027 No description available WB:WBGene00174280 21ur-12920 No description available WB:WBGene00174281 21ur-14811 No description available WB:WBGene00174282 21ur-6029 No description available WB:WBGene00174283 21ur-9996 No description available WB:WBGene00174284 21ur-14268 No description available WB:WBGene00174285 21ur-13872 No description available WB:WBGene00174286 21ur-8318 No description available WB:WBGene00174287 21ur-7033 No description available WB:WBGene00174288 21ur-6933 No description available WB:WBGene00174289 21ur-11345 No description available WB:WBGene00174290 21ur-15300 No description available WB:WBGene00174291 21ur-7611 No description available WB:WBGene00174292 21ur-9480 No description available WB:WBGene00174293 21ur-12668 No description available WB:WBGene00174294 21ur-5791 No description available WB:WBGene00174295 21ur-12647 No description available WB:WBGene00174296 21ur-8013 No description available WB:WBGene00174297 21ur-6649 Enriched in neurons based on RNA-seq studies. WB:WBGene00174298 21ur-9890 No description available WB:WBGene00174299 21ur-11061 No description available WB:WBGene00174300 21ur-5702 No description available WB:WBGene00174301 21ur-9696 No description available WB:WBGene00174302 21ur-11817 No description available WB:WBGene00174303 21ur-10859 No description available WB:WBGene00174304 21ur-13658 No description available WB:WBGene00174305 21ur-12151 No description available WB:WBGene00174306 21ur-13893 No description available WB:WBGene00174307 21ur-9925 No description available WB:WBGene00174308 21ur-8078 No description available WB:WBGene00174309 21ur-14325 No description available WB:WBGene00174310 21ur-9352 No description available WB:WBGene00174311 21ur-14951 Is affected by chd-3 and wdr-5.1 based on RNA-seq studies. WB:WBGene00174312 21ur-6137 No description available WB:WBGene00174313 21ur-6734 No description available WB:WBGene00174314 21ur-9036 Enriched in neurons based on RNA-seq studies. WB:WBGene00174315 21ur-10686 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00174316 21ur-12233 No description available WB:WBGene00174317 21ur-11234 No description available WB:WBGene00174318 21ur-9786 No description available WB:WBGene00174319 21ur-6618 No description available WB:WBGene00174320 21ur-10283 No description available WB:WBGene00174321 21ur-14825 No description available WB:WBGene00174322 21ur-14519 Is affected by sid-2 based on RNA-seq studies. WB:WBGene00174323 21ur-6334 No description available WB:WBGene00174324 21ur-11624 No description available WB:WBGene00174325 21ur-7940 No description available WB:WBGene00174326 21ur-7790 No description available WB:WBGene00174327 21ur-7587 No description available WB:WBGene00174328 21ur-13068 No description available WB:WBGene00174329 21ur-7148 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00174330 21ur-10623 No description available WB:WBGene00174331 21ur-14830 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00174332 21ur-15542 No description available WB:WBGene00174333 21ur-14862 No description available WB:WBGene00174334 21ur-9978 No description available WB:WBGene00174335 21ur-5868 No description available WB:WBGene00174336 21ur-9779 No description available WB:WBGene00174337 21ur-8067 No description available WB:WBGene00174338 21ur-10437 No description available WB:WBGene00174339 21ur-13453 Is affected by daf-16 and blmp-1 based on RNA-seq studies. Is affected by juglone based on RNA-seq studies. WB:WBGene00174340 21ur-5847 No description available WB:WBGene00174341 21ur-9271 No description available WB:WBGene00174342 21ur-11846 No description available WB:WBGene00174343 21ur-13529 No description available WB:WBGene00174344 21ur-11510 No description available WB:WBGene00174345 21ur-8678 Enriched in neurons based on RNA-seq studies. WB:WBGene00174346 21ur-11001 No description available WB:WBGene00174347 21ur-14487 No description available WB:WBGene00174348 21ur-8311 No description available WB:WBGene00174349 21ur-8006 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00174350 21ur-12031 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174351 21ur-11068 No description available WB:WBGene00174352 21ur-8671 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00174353 21ur-13648 No description available WB:WBGene00174354 21ur-15213 No description available WB:WBGene00174355 21ur-8888 No description available WB:WBGene00174356 21ur-12172 No description available WB:WBGene00174357 21ur-15308 No description available WB:WBGene00174358 21ur-14104 No description available WB:WBGene00174359 21ur-11049 No description available WB:WBGene00174360 21ur-13915 Enriched in neurons based on RNA-seq studies. WB:WBGene00174361 21ur-8033 No description available WB:WBGene00174362 21ur-8240 No description available WB:WBGene00174363 21ur-6676 Enriched in neurons based on RNA-seq studies. WB:WBGene00174364 21ur-10616 No description available WB:WBGene00174365 21ur-9629 No description available WB:WBGene00174366 21ur-12218 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00174367 21ur-11619 No description available WB:WBGene00174368 21ur-11725 No description available WB:WBGene00174369 21ur-12834 No description available WB:WBGene00174370 21ur-7619 No description available WB:WBGene00174371 21ur-6248 No description available WB:WBGene00174372 21ur-6057 No description available WB:WBGene00174373 21ur-15198 No description available WB:WBGene00174374 21ur-12947 No description available WB:WBGene00174375 21ur-8085 No description available WB:WBGene00174376 21ur-9285 No description available WB:WBGene00174377 21ur-14361 No description available WB:WBGene00174378 21ur-5736 No description available WB:WBGene00174379 21ur-11042 No description available WB:WBGene00174380 21ur-9307 No description available WB:WBGene00174381 21ur-7504 No description available WB:WBGene00174382 21ur-11892 No description available WB:WBGene00174383 21ur-7051 No description available WB:WBGene00174384 21ur-13177 No description available WB:WBGene00174385 21ur-7438 No description available WB:WBGene00174386 21ur-8340 No description available WB:WBGene00174387 21ur-10552 No description available WB:WBGene00174388 21ur-11488 No description available WB:WBGene00174389 21ur-8217 No description available WB:WBGene00174390 21ur-14528 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00174391 21ur-13261 No description available WB:WBGene00174392 21ur-6416 No description available WB:WBGene00174393 21ur-11514 No description available WB:WBGene00174394 21ur-10441 No description available WB:WBGene00174395 21ur-10886 No description available WB:WBGene00174396 21ur-14167 No description available WB:WBGene00174397 21ur-7603 No description available WB:WBGene00174398 21ur-7189 No description available WB:WBGene00174399 21ur-12914 No description available WB:WBGene00174400 21ur-10423 No description available WB:WBGene00174401 21ur-5852 No description available WB:WBGene00174402 21ur-9109 No description available WB:WBGene00174403 21ur-5487 No description available WB:WBGene00174404 21ur-13043 No description available WB:WBGene00174405 21ur-5836 No description available WB:WBGene00174406 21ur-12530 No description available WB:WBGene00174407 21ur-7858 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00174408 21ur-11011 No description available WB:WBGene00174409 21ur-5929 No description available WB:WBGene00174410 21ur-10456 No description available WB:WBGene00174411 21ur-8544 No description available WB:WBGene00174412 21ur-7397 No description available WB:WBGene00174413 21ur-8610 No description available WB:WBGene00174414 21ur-14687 No description available WB:WBGene00174415 21ur-14684 No description available WB:WBGene00174416 21ur-7818 No description available WB:WBGene00174417 21ur-13974 No description available WB:WBGene00174418 21ur-8074 No description available WB:WBGene00174419 21ur-6971 No description available WB:WBGene00174420 21ur-10897 No description available WB:WBGene00174421 21ur-13787 No description available WB:WBGene00174422 21ur-8904 No description available WB:WBGene00174423 21ur-10056 No description available WB:WBGene00174424 21ur-14440 No description available WB:WBGene00174425 21ur-13360 No description available WB:WBGene00174426 21ur-7730 No description available WB:WBGene00174427 21ur-11690 No description available WB:WBGene00174428 21ur-12168 No description available WB:WBGene00174429 21ur-8306 No description available WB:WBGene00174430 21ur-7459 No description available WB:WBGene00174431 21ur-11413 No description available WB:WBGene00174432 21ur-13286 No description available WB:WBGene00174433 21ur-15423 No description available WB:WBGene00174434 21ur-12461 Is affected by emr-1; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00174435 21ur-7452 No description available WB:WBGene00174436 21ur-11957 No description available WB:WBGene00174437 21ur-7372 No description available WB:WBGene00174438 21ur-14813 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174439 21ur-7677 No description available WB:WBGene00174440 21ur-11649 No description available WB:WBGene00174441 21ur-8112 No description available WB:WBGene00174442 21ur-11140 No description available WB:WBGene00174443 21ur-13291 No description available WB:WBGene00174444 21ur-9883 No description available WB:WBGene00174445 21ur-7883 No description available WB:WBGene00174446 21ur-6754 No description available WB:WBGene00174447 21ur-6829 No description available WB:WBGene00174448 21ur-15343 No description available WB:WBGene00174449 21ur-10334 No description available WB:WBGene00174450 21ur-11640 No description available WB:WBGene00174451 21ur-11361 No description available WB:WBGene00174452 21ur-12140 No description available WB:WBGene00174453 21ur-6480 No description available WB:WBGene00174454 21ur-15006 Enriched in neurons based on RNA-seq studies. Is affected by emr-1; lem-2; and set-2 based on RNA-seq studies. WB:WBGene00174455 21ur-5654 No description available WB:WBGene00174456 21ur-12469 No description available WB:WBGene00174457 21ur-12917 No description available WB:WBGene00174458 21ur-8117 No description available WB:WBGene00174459 21ur-11741 No description available WB:WBGene00174460 21ur-9364 No description available WB:WBGene00174461 21ur-6823 No description available WB:WBGene00174462 21ur-11998 No description available WB:WBGene00174463 21ur-5908 No description available WB:WBGene00174464 21ur-12601 No description available WB:WBGene00174465 21ur-14550 No description available WB:WBGene00174466 21ur-5574 No description available WB:WBGene00174467 21ur-10359 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00174468 21ur-14753 No description available WB:WBGene00174469 21ur-13721 No description available WB:WBGene00174470 21ur-5888 No description available WB:WBGene00174471 21ur-9887 No description available WB:WBGene00174472 21ur-13330 No description available WB:WBGene00174473 21ur-6724 No description available WB:WBGene00174474 21ur-8471 No description available WB:WBGene00174475 21ur-14645 No description available WB:WBGene00174476 21ur-11534 No description available WB:WBGene00174477 21ur-5963 No description available WB:WBGene00174478 21ur-14989 No description available WB:WBGene00174479 21ur-7913 No description available WB:WBGene00174480 21ur-8051 No description available WB:WBGene00174481 21ur-10068 No description available WB:WBGene00174482 21ur-7993 No description available WB:WBGene00174483 21ur-5931 No description available WB:WBGene00174484 21ur-5782 No description available WB:WBGene00174485 21ur-6151 No description available WB:WBGene00174486 21ur-10750 No description available WB:WBGene00174487 21ur-14606 No description available WB:WBGene00174488 21ur-14351 Is affected by hpl-2 and ikb-1 based on RNA-seq studies. WB:WBGene00174489 21ur-8490 No description available WB:WBGene00174490 21ur-12806 No description available WB:WBGene00174491 21ur-8391 No description available WB:WBGene00174492 21ur-14463 No description available WB:WBGene00174493 21ur-13769 No description available WB:WBGene00174494 21ur-6555 No description available WB:WBGene00174495 21ur-11251 No description available WB:WBGene00174496 21ur-15374 No description available WB:WBGene00174497 21ur-14796 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00174498 21ur-5711 No description available WB:WBGene00174499 21ur-8131 No description available WB:WBGene00174500 21ur-6173 No description available WB:WBGene00174501 21ur-12211 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174502 21ur-12651 No description available WB:WBGene00174503 21ur-8276 No description available WB:WBGene00174504 21ur-15154 No description available WB:WBGene00174505 21ur-8119 No description available WB:WBGene00174506 21ur-10164 No description available WB:WBGene00174507 21ur-12430 No description available WB:WBGene00174508 21ur-9238 No description available WB:WBGene00174509 21ur-6537 No description available WB:WBGene00174510 21ur-6830 No description available WB:WBGene00174511 21ur-15076 No description available WB:WBGene00174512 21ur-14346 No description available WB:WBGene00174513 21ur-12799 No description available WB:WBGene00174514 21ur-10236 No description available WB:WBGene00174515 21ur-11050 No description available WB:WBGene00174516 21ur-11406 No description available WB:WBGene00174517 21ur-8202 No description available WB:WBGene00174518 21ur-9558 No description available WB:WBGene00174519 21ur-10820 No description available WB:WBGene00174520 21ur-15571 No description available WB:WBGene00174521 21ur-14065 No description available WB:WBGene00174522 21ur-14449 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00174523 21ur-11462 No description available WB:WBGene00174524 21ur-7651 No description available WB:WBGene00174525 21ur-15246 No description available WB:WBGene00174526 21ur-6505 No description available WB:WBGene00174527 21ur-11555 No description available WB:WBGene00174528 21ur-14171 No description available WB:WBGene00174529 21ur-7290 No description available WB:WBGene00174530 21ur-11270 No description available WB:WBGene00174531 21ur-10538 No description available WB:WBGene00174532 21ur-10996 No description available WB:WBGene00174533 21ur-5689 No description available WB:WBGene00174534 21ur-7463 No description available WB:WBGene00174535 21ur-9681 No description available WB:WBGene00174536 21ur-9317 No description available WB:WBGene00174537 21ur-7153 No description available WB:WBGene00174538 21ur-9831 No description available WB:WBGene00174539 21ur-7773 No description available WB:WBGene00174540 21ur-9809 No description available WB:WBGene00174541 21ur-13011 Enriched in sensory neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00174542 21ur-12174 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00174543 21ur-15450 No description available WB:WBGene00174544 21ur-13536 No description available WB:WBGene00174545 21ur-9171 No description available WB:WBGene00174546 21ur-10030 No description available WB:WBGene00174547 21ur-13889 No description available WB:WBGene00174548 21ur-11277 No description available WB:WBGene00174549 21ur-11150 No description available WB:WBGene00174550 21ur-14146 No description available WB:WBGene00174551 21ur-6420 No description available WB:WBGene00174552 21ur-12265 No description available WB:WBGene00174553 21ur-10297 No description available WB:WBGene00174554 21ur-10994 No description available WB:WBGene00174555 21ur-13132 No description available WB:WBGene00174556 21ur-6696 No description available WB:WBGene00174557 21ur-13373 No description available WB:WBGene00174558 21ur-14583 No description available WB:WBGene00174559 21ur-12497 No description available WB:WBGene00174560 21ur-9936 No description available WB:WBGene00174561 21ur-7712 Enriched in neurons based on RNA-seq studies. WB:WBGene00174562 21ur-8110 No description available WB:WBGene00174563 21ur-8633 No description available WB:WBGene00174564 21ur-13487 No description available WB:WBGene00174565 21ur-13525 No description available WB:WBGene00174566 21ur-14432 No description available WB:WBGene00174567 21ur-8525 No description available WB:WBGene00174568 21ur-10609 No description available WB:WBGene00174569 21ur-11793 No description available WB:WBGene00174570 21ur-6674 No description available WB:WBGene00174571 21ur-12257 No description available WB:WBGene00174572 21ur-10259 No description available WB:WBGene00174573 21ur-9414 No description available WB:WBGene00174574 21ur-13679 No description available WB:WBGene00174575 21ur-12758 No description available WB:WBGene00174576 21ur-10574 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174577 21ur-10594 Enriched in neurons based on RNA-seq studies. WB:WBGene00174578 21ur-12543 No description available WB:WBGene00174579 21ur-11516 No description available WB:WBGene00174580 21ur-8594 No description available WB:WBGene00174581 21ur-9642 No description available WB:WBGene00174582 21ur-9907 No description available WB:WBGene00174583 21ur-10579 No description available WB:WBGene00174584 21ur-11191 No description available WB:WBGene00174585 21ur-6499 No description available WB:WBGene00174586 21ur-6961 No description available WB:WBGene00174587 21ur-9802 No description available WB:WBGene00174588 21ur-12550 No description available WB:WBGene00174589 21ur-6182 No description available WB:WBGene00174590 21ur-10633 No description available WB:WBGene00174591 21ur-12001 Is affected by daf-2 based on microarray studies. WB:WBGene00174592 21ur-6364 No description available WB:WBGene00174593 21ur-6795 No description available WB:WBGene00174594 21ur-5707 No description available WB:WBGene00174595 21ur-6158 No description available WB:WBGene00174596 21ur-10939 No description available WB:WBGene00174597 21ur-9742 No description available WB:WBGene00174598 21ur-13824 No description available WB:WBGene00174599 21ur-9545 No description available WB:WBGene00174600 21ur-9372 No description available WB:WBGene00174601 21ur-11226 No description available WB:WBGene00174602 21ur-6304 No description available WB:WBGene00174603 21ur-10706 No description available WB:WBGene00174604 21ur-5763 No description available WB:WBGene00174605 21ur-14613 No description available WB:WBGene00174606 21ur-7839 No description available WB:WBGene00174607 21ur-6936 No description available WB:WBGene00174608 21ur-7514 No description available WB:WBGene00174609 21ur-6336 No description available WB:WBGene00174610 21ur-6596 No description available WB:WBGene00174611 21ur-9127 No description available WB:WBGene00174612 21ur-9914 No description available WB:WBGene00174613 21ur-6072 No description available WB:WBGene00174614 21ur-9688 No description available WB:WBGene00174615 21ur-8175 No description available WB:WBGene00174616 21ur-11908 No description available WB:WBGene00174617 21ur-6191 No description available WB:WBGene00174618 21ur-12473 No description available WB:WBGene00174619 21ur-8449 No description available WB:WBGene00174620 21ur-10796 No description available WB:WBGene00174621 21ur-6443 Is affected by smn-1 based on RNA-seq studies. WB:WBGene00174622 21ur-15278 No description available WB:WBGene00174623 21ur-10252 No description available WB:WBGene00174624 21ur-12305 No description available WB:WBGene00174625 21ur-13653 Enriched in neurons based on RNA-seq studies. WB:WBGene00174626 21ur-11881 No description available WB:WBGene00174627 21ur-11699 No description available WB:WBGene00174628 21ur-9583 No description available WB:WBGene00174629 21ur-10974 No description available WB:WBGene00174630 21ur-15478 No description available WB:WBGene00174631 21ur-8095 Enriched in neurons based on RNA-seq studies. WB:WBGene00174632 21ur-8811 No description available WB:WBGene00174633 21ur-6319 No description available WB:WBGene00174634 21ur-12951 No description available WB:WBGene00174635 21ur-7516 No description available WB:WBGene00174636 21ur-7532 No description available WB:WBGene00174637 21ur-7561 No description available WB:WBGene00174638 21ur-5863 No description available WB:WBGene00174639 21ur-11149 No description available WB:WBGene00174640 21ur-12862 No description available WB:WBGene00174641 21ur-7182 No description available WB:WBGene00174642 21ur-15687 No description available WB:WBGene00174643 21ur-5808 No description available WB:WBGene00174644 21ur-13090 No description available WB:WBGene00174645 21ur-9768 No description available WB:WBGene00174646 21ur-14094 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. WB:WBGene00174647 21ur-12880 No description available WB:WBGene00174648 21ur-15601 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00174649 21ur-14261 No description available WB:WBGene00174650 21ur-12162 No description available WB:WBGene00174651 21ur-11081 No description available WB:WBGene00174652 21ur-9567 No description available WB:WBGene00174653 21ur-11384 No description available WB:WBGene00174654 21ur-15656 No description available WB:WBGene00174655 21ur-8972 Enriched in neurons based on RNA-seq studies. WB:WBGene00174656 21ur-11059 No description available WB:WBGene00174657 21ur-10956 No description available WB:WBGene00174658 21ur-7375 No description available WB:WBGene00174659 21ur-5516 No description available WB:WBGene00174660 21ur-10290 No description available WB:WBGene00174661 21ur-8294 No description available WB:WBGene00174662 21ur-7638 Is affected by Zidovudine based on RNA-seq studies. WB:WBGene00174663 21ur-13309 Enriched in neurons based on RNA-seq studies. WB:WBGene00174664 21ur-15023 No description available WB:WBGene00174665 21ur-15397 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00174666 21ur-14747 No description available WB:WBGene00174667 21ur-6489 No description available WB:WBGene00174668 21ur-7489 No description available WB:WBGene00174669 21ur-6384 No description available WB:WBGene00174670 21ur-11809 No description available WB:WBGene00174671 21ur-15020 No description available WB:WBGene00174672 21ur-10933 No description available WB:WBGene00174673 21ur-11368 No description available WB:WBGene00174674 21ur-7240 No description available WB:WBGene00174675 21ur-7931 No description available WB:WBGene00174676 21ur-13230 No description available WB:WBGene00174677 21ur-11705 No description available WB:WBGene00174678 21ur-12512 No description available WB:WBGene00174679 21ur-9467 No description available WB:WBGene00174680 21ur-8257 No description available WB:WBGene00174681 21ur-5587 No description available WB:WBGene00174682 21ur-12991 No description available WB:WBGene00174683 21ur-13932 No description available WB:WBGene00174684 21ur-14934 Enriched in neurons based on RNA-seq studies. WB:WBGene00174685 21ur-12041 No description available WB:WBGene00174686 21ur-13415 No description available WB:WBGene00174687 21ur-7342 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00174688 21ur-12743 No description available WB:WBGene00174689 21ur-7344 No description available WB:WBGene00174690 21ur-9670 No description available WB:WBGene00174691 21ur-13777 No description available WB:WBGene00174692 21ur-6942 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00174693 21ur-12956 No description available WB:WBGene00174694 21ur-7757 No description available WB:WBGene00174695 21ur-11071 No description available WB:WBGene00174696 21ur-11320 No description available WB:WBGene00174697 21ur-12526 No description available WB:WBGene00174698 21ur-14896 No description available WB:WBGene00174699 21ur-13822 No description available WB:WBGene00174700 21ur-8154 No description available WB:WBGene00174701 21ur-11333 No description available WB:WBGene00174702 21ur-12922 No description available WB:WBGene00174703 21ur-9253 No description available WB:WBGene00174704 21ur-7830 No description available WB:WBGene00174705 21ur-10588 No description available WB:WBGene00174706 21ur-7421 No description available WB:WBGene00174707 21ur-13851 No description available WB:WBGene00174708 21ur-11178 Enriched in neurons based on RNA-seq studies. WB:WBGene00174709 21ur-13034 No description available WB:WBGene00174710 21ur-7403 No description available WB:WBGene00174711 21ur-10557 No description available WB:WBGene00174712 21ur-8653 Is affected by hrpr-1 and mrps-5 based on RNA-seq studies. WB:WBGene00174713 21ur-8664 No description available WB:WBGene00174714 21ur-6373 No description available WB:WBGene00174715 21ur-10831 No description available WB:WBGene00174716 21ur-12078 No description available WB:WBGene00174717 21ur-10039 No description available WB:WBGene00174718 21ur-7390 No description available WB:WBGene00174719 21ur-9120 No description available WB:WBGene00174720 21ur-5743 No description available WB:WBGene00174721 21ur-5823 No description available WB:WBGene00174722 21ur-5628 No description available WB:WBGene00174723 21ur-15231 No description available WB:WBGene00174724 21ur-14118 No description available WB:WBGene00174725 21ur-9156 No description available WB:WBGene00174726 21ur-10371 No description available WB:WBGene00174727 21ur-6063 No description available WB:WBGene00174728 21ur-11675 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174729 21ur-5633 Enriched in neurons based on RNA-seq studies. WB:WBGene00174730 21ur-10696 No description available WB:WBGene00174731 21ur-7335 Is affected by eat-2 based on microarray studies. WB:WBGene00174732 21ur-13010 No description available WB:WBGene00174733 21ur-15234 No description available WB:WBGene00174734 21ur-13194 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174735 21ur-7975 No description available WB:WBGene00174736 21ur-7230 No description available WB:WBGene00174737 21ur-12714 No description available WB:WBGene00174738 21ur-5602 No description available WB:WBGene00174739 21ur-9593 No description available WB:WBGene00174740 21ur-13337 No description available WB:WBGene00174741 21ur-13310 Enriched in neurons based on RNA-seq studies. WB:WBGene00174742 21ur-15696 Enriched in neurons based on RNA-seq studies. WB:WBGene00174743 21ur-11667 No description available WB:WBGene00174744 21ur-13216 Enriched in neurons based on RNA-seq studies. WB:WBGene00174745 21ur-7046 Enriched in neurons based on RNA-seq studies. WB:WBGene00174746 21ur-9828 No description available WB:WBGene00174747 21ur-9536 No description available WB:WBGene00174748 21ur-15459 No description available WB:WBGene00174749 21ur-9214 No description available WB:WBGene00174750 21ur-11764 No description available WB:WBGene00174751 21ur-12628 No description available WB:WBGene00174752 21ur-6841 No description available WB:WBGene00174753 21ur-14969 No description available WB:WBGene00174754 21ur-9193 No description available WB:WBGene00174755 21ur-8437 No description available WB:WBGene00174756 21ur-8444 No description available WB:WBGene00174757 21ur-10341 Enriched in neurons based on RNA-seq studies. WB:WBGene00174758 21ur-12565 No description available WB:WBGene00174759 21ur-5901 No description available WB:WBGene00174760 21ur-15525 No description available WB:WBGene00174761 21ur-10190 No description available WB:WBGene00174762 21ur-5920 No description available WB:WBGene00174763 21ur-14877 No description available WB:WBGene00174764 21ur-15560 No description available WB:WBGene00174765 21ur-6007 No description available WB:WBGene00174766 21ur-5606 No description available WB:WBGene00174767 21ur-10424 No description available WB:WBGene00174768 21ur-6333 No description available WB:WBGene00174769 21ur-6077 No description available WB:WBGene00174770 21ur-12380 No description available WB:WBGene00174771 21ur-6903 No description available WB:WBGene00174772 21ur-15182 No description available WB:WBGene00174773 21ur-14023 No description available WB:WBGene00174774 21ur-6223 No description available WB:WBGene00174775 21ur-6913 No description available WB:WBGene00174776 21ur-7289 No description available WB:WBGene00174777 21ur-12006 No description available WB:WBGene00174778 21ur-12447 No description available WB:WBGene00174779 21ur-13764 No description available WB:WBGene00174780 21ur-8517 No description available WB:WBGene00174781 21ur-15201 Enriched in neurons based on RNA-seq studies. WB:WBGene00174782 21ur-6016 No description available WB:WBGene00174783 21ur-13801 No description available WB:WBGene00174784 21ur-13735 No description available WB:WBGene00174785 21ur-15401 No description available WB:WBGene00174786 21ur-8146 No description available WB:WBGene00174787 21ur-12877 No description available WB:WBGene00174788 21ur-8329 No description available WB:WBGene00174789 21ur-15253 No description available WB:WBGene00174790 21ur-11688 No description available WB:WBGene00174791 21ur-6231 No description available WB:WBGene00174792 21ur-12119 No description available WB:WBGene00174793 21ur-8195 No description available WB:WBGene00174794 21ur-15429 No description available WB:WBGene00174795 21ur-13472 No description available WB:WBGene00174796 21ur-11078 No description available WB:WBGene00174797 21ur-9509 Enriched in neurons based on RNA-seq studies. WB:WBGene00174798 21ur-12234 No description available WB:WBGene00174799 21ur-9180 No description available WB:WBGene00174800 21ur-8994 No description available WB:WBGene00174801 21ur-10036 No description available WB:WBGene00174802 21ur-10464 No description available WB:WBGene00174803 21ur-12996 No description available WB:WBGene00174804 21ur-12338 No description available WB:WBGene00174805 21ur-6268 No description available WB:WBGene00174806 21ur-7172 Is affected by eat-2 based on microarray studies. WB:WBGene00174807 21ur-15417 No description available WB:WBGene00174808 21ur-10784 Enriched in neurons based on RNA-seq studies. WB:WBGene00174809 21ur-12062 No description available WB:WBGene00174810 21ur-10086 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00174811 21ur-7050 No description available WB:WBGene00174812 21ur-12366 No description available WB:WBGene00174813 21ur-8188 No description available WB:WBGene00174814 21ur-14478 No description available WB:WBGene00174815 21ur-9118 No description available WB:WBGene00174816 21ur-14390 No description available WB:WBGene00174817 21ur-8218 No description available WB:WBGene00174818 21ur-14052 No description available WB:WBGene00174819 21ur-9956 No description available WB:WBGene00174820 21ur-10977 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174821 21ur-5956 No description available WB:WBGene00174822 21ur-12178 No description available WB:WBGene00174823 21ur-10665 No description available WB:WBGene00174824 21ur-6792 No description available WB:WBGene00174825 21ur-10050 No description available WB:WBGene00174826 21ur-15700 Is affected by hpl-2 and hlh-26 based on RNA-seq studies. WB:WBGene00174827 21ur-6432 No description available WB:WBGene00174828 21ur-10094 Enriched in AFD based on RNA-seq studies. WB:WBGene00174829 21ur-13229 No description available WB:WBGene00174830 21ur-14027 No description available WB:WBGene00174831 21ur-14423 No description available WB:WBGene00174832 21ur-6147 No description available WB:WBGene00174833 21ur-11453 No description available WB:WBGene00174834 21ur-12936 No description available WB:WBGene00174835 21ur-8848 No description available WB:WBGene00174836 21ur-9166 No description available WB:WBGene00174837 21ur-13608 No description available WB:WBGene00174838 21ur-7720 No description available WB:WBGene00174839 21ur-7324 No description available WB:WBGene00174840 21ur-6320 No description available WB:WBGene00174841 21ur-10383 No description available WB:WBGene00174842 21ur-5720 No description available WB:WBGene00174843 21ur-11341 No description available WB:WBGene00174844 21ur-12109 No description available WB:WBGene00174845 21ur-10951 No description available WB:WBGene00174846 21ur-6709 No description available WB:WBGene00174847 21ur-11489 Enriched in neurons based on RNA-seq studies. WB:WBGene00174848 21ur-14210 No description available WB:WBGene00174849 21ur-6817 No description available WB:WBGene00174850 21ur-13925 No description available WB:WBGene00174851 21ur-8863 No description available WB:WBGene00174852 21ur-15129 Enriched in neurons based on RNA-seq studies. WB:WBGene00174853 21ur-12429 No description available WB:WBGene00174854 21ur-7108 Enriched in neurons based on RNA-seq studies. WB:WBGene00174855 21ur-12851 No description available WB:WBGene00174856 21ur-11851 No description available WB:WBGene00174857 21ur-10727 No description available WB:WBGene00174858 21ur-6958 No description available WB:WBGene00174859 21ur-13567 No description available WB:WBGene00174860 21ur-6261 No description available WB:WBGene00174861 21ur-13250 Enriched in neurons based on RNA-seq studies. WB:WBGene00174862 21ur-8980 No description available WB:WBGene00174863 21ur-13005 No description available WB:WBGene00174864 21ur-13224 No description available WB:WBGene00174865 21ur-6813 Enriched in neurons based on RNA-seq studies. WB:WBGene00174866 21ur-6584 No description available WB:WBGene00174867 21ur-11470 No description available WB:WBGene00174868 21ur-9160 No description available WB:WBGene00174869 21ur-12385 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174870 21ur-9450 No description available WB:WBGene00174871 21ur-7297 No description available WB:WBGene00174872 21ur-15492 No description available WB:WBGene00174873 21ur-7096 No description available WB:WBGene00174874 21ur-7208 No description available WB:WBGene00174875 21ur-9167 No description available WB:WBGene00174876 21ur-5647 No description available WB:WBGene00174877 21ur-8744 No description available WB:WBGene00174878 21ur-8125 No description available WB:WBGene00174879 21ur-12299 No description available WB:WBGene00174880 21ur-14208 No description available WB:WBGene00174881 21ur-12488 No description available WB:WBGene00174882 21ur-13400 No description available WB:WBGene00174883 21ur-14184 No description available WB:WBGene00174884 21ur-10311 No description available WB:WBGene00174885 21ur-13070 No description available WB:WBGene00174886 21ur-13808 No description available WB:WBGene00174887 21ur-15296 No description available WB:WBGene00174888 21ur-11958 No description available WB:WBGene00174889 21ur-6123 No description available WB:WBGene00174890 21ur-11834 No description available WB:WBGene00174891 21ur-9063 No description available WB:WBGene00174892 21ur-9577 No description available WB:WBGene00174893 21ur-10153 Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00174894 21ur-11157 No description available WB:WBGene00174895 21ur-14776 No description available WB:WBGene00174896 21ur-11848 No description available WB:WBGene00174897 21ur-11314 No description available WB:WBGene00174898 21ur-7670 No description available WB:WBGene00174899 21ur-14996 No description available WB:WBGene00174900 21ur-9425 Is affected by set-2 based on RNA-seq studies. WB:WBGene00174901 21ur-7219 Enriched in neurons based on RNA-seq studies. WB:WBGene00174902 21ur-7546 No description available WB:WBGene00174903 21ur-8623 No description available WB:WBGene00174904 21ur-6701 No description available WB:WBGene00174905 21ur-14539 No description available WB:WBGene00174906 21ur-7882 No description available WB:WBGene00174907 21ur-12097 No description available WB:WBGene00174908 21ur-7668 No description available WB:WBGene00174909 21ur-14059 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00174910 21ur-9222 No description available WB:WBGene00174911 21ur-10417 No description available WB:WBGene00174912 21ur-6777 No description available WB:WBGene00174913 21ur-14781 No description available WB:WBGene00174914 21ur-11482 No description available WB:WBGene00174915 21ur-10596 No description available WB:WBGene00174916 21ur-13284 No description available WB:WBGene00174917 21ur-12863 No description available WB:WBGene00174918 21ur-8712 No description available WB:WBGene00174919 21ur-12982 No description available WB:WBGene00174920 21ur-7661 No description available WB:WBGene00174921 21ur-11327 No description available WB:WBGene00174922 21ur-7484 No description available WB:WBGene00174923 21ur-6400 No description available WB:WBGene00174924 21ur-9434 No description available WB:WBGene00174925 21ur-14999 Enriched in neurons based on RNA-seq studies. WB:WBGene00174926 21ur-9500 No description available WB:WBGene00174927 21ur-15580 No description available WB:WBGene00174928 21ur-10197 No description available WB:WBGene00174929 21ur-11929 No description available WB:WBGene00174930 21ur-11944 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00174931 21ur-12889 Is affected by daf-2 based on microarray studies. WB:WBGene00174932 21ur-5797 No description available WB:WBGene00174933 21ur-9616 Enriched in neurons based on RNA-seq studies. WB:WBGene00174934 21ur-8358 No description available WB:WBGene00174935 21ur-10100 No description available WB:WBGene00174936 21ur-8714 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00174937 21ur-12044 No description available WB:WBGene00174938 21ur-7804 No description available WB:WBGene00174939 21ur-13990 No description available WB:WBGene00174940 21ur-13985 No description available WB:WBGene00174941 21ur-13105 No description available WB:WBGene00174942 21ur-10451 No description available WB:WBGene00174943 21ur-14885 No description available WB:WBGene00174944 21ur-10061 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00174945 21ur-11183 No description available WB:WBGene00174946 21ur-9014 No description available WB:WBGene00174947 21ur-11734 No description available WB:WBGene00174948 21ur-12848 No description available WB:WBGene00174949 21ur-8208 No description available WB:WBGene00174950 21ur-10938 No description available WB:WBGene00174951 21ur-10079 No description available WB:WBGene00174952 21ur-9723 No description available WB:WBGene00174953 21ur-13173 No description available WB:WBGene00174954 21ur-12719 No description available WB:WBGene00174955 21ur-12284 Enriched in neurons based on RNA-seq studies. WB:WBGene00174956 21ur-9057 No description available WB:WBGene00174957 21ur-13467 No description available WB:WBGene00174958 21ur-9338 No description available WB:WBGene00174959 21ur-15157 No description available WB:WBGene00174960 21ur-9738 No description available WB:WBGene00174961 21ur-14628 No description available WB:WBGene00174962 21ur-10128 Is affected by several genes including emr-1; hmg-4; and hmg-3 based on RNA-seq studies. WB:WBGene00174963 21ur-11017 No description available WB:WBGene00174964 21ur-7551 Is affected by daf-2 based on microarray studies. WB:WBGene00174965 21ur-11218 Enriched in neurons based on RNA-seq studies. WB:WBGene00174966 21ur-14724 No description available WB:WBGene00174967 21ur-9815 No description available WB:WBGene00174968 21ur-13022 No description available WB:WBGene00174969 21ur-11477 No description available WB:WBGene00174970 21ur-8222 No description available WB:WBGene00174971 21ur-15302 Enriched in neurons based on RNA-seq studies. WB:WBGene00174972 21ur-14914 No description available WB:WBGene00174973 21ur-8501 No description available WB:WBGene00174974 21ur-9858 No description available WB:WBGene00174975 21ur-14217 No description available WB:WBGene00174976 21ur-14860 No description available WB:WBGene00174977 21ur-12612 No description available WB:WBGene00174978 21ur-7472 No description available WB:WBGene00174979 21ur-8423 No description available WB:WBGene00174980 21ur-9407 No description available WB:WBGene00174981 21ur-14016 No description available WB:WBGene00174982 21ur-14975 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00174983 21ur-12333 No description available WB:WBGene00174984 21ur-15263 No description available WB:WBGene00174985 21ur-12130 No description available WB:WBGene00174986 21ur-14706 No description available WB:WBGene00174987 21ur-9102 No description available WB:WBGene00174988 21ur-12327 Enriched in neurons based on RNA-seq studies. WB:WBGene00174989 21ur-8457 No description available WB:WBGene00174990 21ur-12402 No description available WB:WBGene00174991 21ur-9654 No description available WB:WBGene00174992 21ur-7201 No description available WB:WBGene00174993 21ur-13903 No description available WB:WBGene00174994 21ur-13046 No description available WB:WBGene00174995 21ur-13759 No description available WB:WBGene00174996 21ur-11813 No description available WB:WBGene00174997 21ur-10744 No description available WB:WBGene00174998 21ur-6715 No description available WB:WBGene00174999 21ur-13055 No description available WB:WBGene00175000 21ur-9196 No description available WB:WBGene00175001 21ur-11973 No description available WB:WBGene00175002 21ur-13835 No description available WB:WBGene00175003 21ur-7028 No description available WB:WBGene00175004 21ur-10412 No description available WB:WBGene00175005 21ur-9402 No description available WB:WBGene00175006 21ur-12105 No description available WB:WBGene00175007 21ur-5640 No description available WB:WBGene00175008 21ur-10842 No description available WB:WBGene00175009 21ur-12508 Is affected by set-2 based on RNA-seq studies. WB:WBGene00175010 21ur-15408 No description available WB:WBGene00175011 21ur-9147 No description available WB:WBGene00175012 21ur-9459 No description available WB:WBGene00175013 21ur-13774 No description available WB:WBGene00175014 21ur-6530 No description available WB:WBGene00175015 21ur-14954 No description available WB:WBGene00175016 21ur-6605 No description available WB:WBGene00175017 21ur-5473 Enriched in neurons based on RNA-seq studies. WB:WBGene00175018 21ur-8264 No description available WB:WBGene00175019 21ur-12978 No description available WB:WBGene00175020 21ur-12320 No description available WB:WBGene00175021 21ur-12014 No description available WB:WBGene00175022 21ur-7743 No description available WB:WBGene00175023 21ur-13085 No description available WB:WBGene00175024 21ur-12540 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00175025 F14E5.7 Is affected by several genes including daf-16; eat-2; and alg-1 based on RNA-seq and microarray studies. Is affected by Humic Substances; paraquat; and silicon dioxide nanoparticle based on microarray and RNA-seq studies. WB:WBGene00175027 W02F12.8 Enriched in several structures, including ADE sheath cell; IL socket cell; anterior hypodermis; arc ant V; and carbon dioxide sensory neurons based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. WB:WBGene00175028 nspe-8 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by procyanidin and Cry5B based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1412) and Protein of unknown function DUF1412. WB:WBGene00175029 AH9.7 Is affected by clk-1 based on microarray studies. Is affected by resveratrol and nitroguanidine based on microarray studies. WB:WBGene00175030 Y53C12A.10 Predicted to enable tRNA-uridine aminocarboxypropyltransferase activity. Predicted to be involved in tRNA modification. Predicted to be located in nucleus. Is an ortholog of human DTWD1 (DTW domain containing 1). WB:WBGene00175031 C06C3.12 Enriched in excretory cell; excretory duct; and excretory pore based on single-cell RNA-seq studies. Is affected by several genes including elt-2; isp-1; and unc-30 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00175034 F54B3.4 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00175035 F54C9.14 Enriched in AVK; B cell; tail precursor cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00175036 Y71A12B.21 Is affected by several genes including daf-16; clk-1; and prg-1 based on RNA-seq and microarray studies. WB:WBGene00175055 dyf-15 No description available WB:WBGene00175056 dyf-16 No description available WB:WBGene00175057 lite-2 No description available WB:WBGene00175058 lite-3 No description available WB:WBGene00184956 F49C5.12 Expressed in CEMDL; CEMDR; CEMVL; CEMVR; and tail. WB:WBGene00184990 C14B1.12 Enriched in several structures, including I5 neuron; MSaapaapa; MSpapaapa; cholinergic neurons; and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; elt-2; and sek-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including rotenone; manganese chloride; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00185001 F56A8.9 Enriched in several structures, including ABplpppapa; ABprpppapa; G2; pharyngeal cell; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; clk-1; and npr-1 based on RNA-seq and microarray studies. Is affected by six chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in osteogenesis imperfecta. Is predicted to encode a protein with the following domains: Coiled-coil domain-containing protein 134 and ERK and JNK pathways, inhibitor. Is an ortholog of human CCDC134 (coiled-coil domain containing 134). WB:WBGene00185002 K11H3.8 Enriched in germ line based on RNA-seq studies. Is affected by several genes including dpy-10; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including manganese chloride; bisphenol S; and stavudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: GYF domain and GYF-like domain superfamily. WB:WBGene00185005 T03F6.10 Enriched in arcade cell; head mesodermal cell; pharyngeal-intestinal valve; and posterior arcade cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including manganese chloride; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00185006 F59B2.15 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including manganese chloride; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00185014 F17C8.9 Predicted to enable NADP binding activity and aspartate dehydrogenase activity. Predicted to be involved in NAD biosynthetic process. Is an ortholog of human ASPDH (aspartate dehydrogenase domain containing). WB:WBGene00185048 urm-1 Predicted to enable protein tag activity. Predicted to be involved in protein urmylation. Predicted to be located in nucleus. Is an ortholog of human URM1 (ubiquitin related modifier 1). WB:WBGene00185055 Y47D3B.12 Is affected by several genes including daf-16; rrf-3; and hsf-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00185067 Y54G11A.17 Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human MRPL27 (mitochondrial ribosomal protein L27). WB:WBGene00185076 Y7A9A.79 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq studies. Is affected by atracurium and paraquat based on RNA-seq studies. WB:WBGene00185077 F58D2.4 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppppapa; ABplpaaappa; and ABpraaapapa based on single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00185078 F40G9.17 Predicted to be part of proteasome complex. Is an ortholog of human PSMD10 (proteasome 26S subunit, non-ATPase 10). WB:WBGene00185079 gvd-1 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and clk-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; Zidovudine; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00185086 F59A3.12 Enriched in DD neuron and germ line based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; dpy-10; and let-7 based on RNA-seq; microarray; and proteomic studies. Is affected by nine chemicals including rotenone; manganese chloride; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00185088 Y55F3BL.4 Enriched in B cell; germ line; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including lin-35; fbf-1; and set-2 based on RNA-seq and microarray studies. Is affected by antimycin; silicon dioxide nanoparticle; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SRR1-like domain and SRR1 domain. WB:WBGene00185089 C16A11.10 Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleus. Is an ortholog of human CLK1 (CDC like kinase 1). WB:WBGene00185092 K08D8.7 Predicted to be located in membrane. WB:WBGene00185093 K08D8.8 Is affected by dpy-21 and hlh-26 based on RNA-seq studies. WB:WBGene00185095 W09C2.7 Enriched in pm6 based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and clk-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Tunicamycin; antimycin; and Cry5B based on microarray and RNA-seq studies. WB:WBGene00185096 W09C2.9 Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. WB:WBGene00185097 C49C3.20 Predicted to be located in membrane. WB:WBGene00185098 Y71G12B.35 Enriched in ABalapppaa; anal sphincter muscle; head mesodermal cell; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; egl-43; and meg-3 based on RNA-seq and microarray studies. Is affected by four chemicals including rotenone; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00185100 T12A7.9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including eri-1; dpy-21; and mut-2 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: AH/BAR domain superfamily. WB:WBGene00185101 Y65A5A.24 Is affected by clk-1 and daf-2 based on microarray studies. WB:WBGene00185102 Y105C5A.1268 Enriched in several structures, including ABalaaaala; DB neuron; accessory cell; germ line; and nerve ring neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00185116 W09C2.8 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by stearic acid and sucrose based on RNA-seq studies. WB:WBGene00185117 C45B11.9 Predicted to be located in membrane. WB:WBGene00185118 K02E2.11 Predicted to enable nucleotidyltransferase activity. WB:WBGene00185119 F16H6.11 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00189930 Y26G10.5 Predicted to be located in membrane. WB:WBGene00189931 Y26G10.6 Enriched in male based on RNA-seq studies. Is affected by several genes including hrde-1; nhl-2; and adr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube; Cry5B; and paraquat based on RNA-seq and microarray studies. WB:WBGene00189932 spp-29 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Saposin-like. WB:WBGene00189933 F38B7.11 Predicted to be located in membrane. WB:WBGene00189937 Y6G8.15 Is affected by several genes including rrf-3; eat-2; and tph-1 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00189943 Y116F11B.17 Is affected by several genes including eat-2; aak-2; and nhr-8 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00189944 E03A3.10 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including rrf-3; clk-1; and dpy-7 based on microarray and RNA-seq studies. Is affected by seven chemicals including 1-methylnicotinamide; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00189946 W04E12.10 Is affected by clk-1 and hlh-26 based on microarray and RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00189947 C06B3.16 Is affected by several genes including eat-2; unc-30; and lem-2 based on RNA-seq and microarray studies. Is affected by Tunicamycin and paraquat based on RNA-seq studies. WB:WBGene00189948 F56H9.8 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; csr-1; and glh-1 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00189949 Y48G1C.13 Predicted to enable chitin binding activity. Predicted to be located in extracellular region. WB:WBGene00189950 C39B5.14 Predicted to be involved in lipid metabolic process. WB:WBGene00189951 linc-29 Enriched in germ line and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by Alovudine and paraquat based on RNA-seq studies. WB:WBGene00189952 K10D2.8 Enriched in head mesodermal cell and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including manganese chloride; Rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Leucine Rich repeat; Leucine Rich repeats (2 copies); Leucine-rich repeat, typical subtype; Leucine-rich repeat; Leucine rich repeat 4; and Leucine-rich repeat domain superfamily. WB:WBGene00189953 R155.5 Enriched in male based on RNA-seq studies. Is affected by several genes including pgl-1; hsp-6; and unc-30 based on RNA-seq studies. Is affected by multi-walled carbon nanotube; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00189954 F40G9.18 Predicted to be located in membrane. WB:WBGene00189955 F40G9.19 Predicted to enable metal ion binding activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Lafora disease. Is an ortholog of human NHLRC1 (NHL repeat containing E3 ubiquitin protein ligase 1). WB:WBGene00189956 Y34F4.6 Predicted to be located in membrane. WB:WBGene00189957 M03F8.7 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00189958 F45H11.8 Enriched in germ line based on RNA-seq studies. Is affected by several genes including hsf-1; clk-1; and pgl-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and paraquat based on RNA-seq and microarray studies. WB:WBGene00189961 Y54G2A.57 Enriched in intestine; neurons; and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00189962 mig-36 No description available WB:WBGene00189963 mig-37 No description available WB:WBGene00189964 F35C11.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00189966 rrn-4.15 Is affected by hpl-2 and adr-1 based on RNA-seq studies. WB:WBGene00189967 Y46G5A.t1 No description available WB:WBGene00189968 ZK1251.14 No description available WB:WBGene00189969 F39B1.3 No description available WB:WBGene00189970 mir-4812 Is affected by alg-5 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and graphene oxide based on RNA-seq studies. WB:WBGene00189971 C41G6.17 No description available WB:WBGene00189972 T10H4.16 No description available WB:WBGene00189973 T10H4.17 Is affected by hmg-3 and blmp-1 based on RNA-seq studies. WB:WBGene00189974 F31C3.12 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00189975 K02E2.12 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00189976 Y39E4B.16 Is affected by sir-2.1 based on microarray studies. WB:WBGene00189977 C47G2.9 No description available WB:WBGene00189978 B0250.14 Enriched in AFD based on RNA-seq studies. WB:WBGene00189979 W04A8.8 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00189980 F02C12.7 Is affected by smg-2; xpf-1; and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00189981 Y60A3A.29 Is affected by dlc-1 and hlh-26 based on RNA-seq studies. WB:WBGene00189982 C06C3.13 No description available WB:WBGene00189983 Y71A12B.22 No description available WB:WBGene00189984 K02E2.13 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00189985 F02D8.8 No description available WB:WBGene00189986 C53D6.16 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00189987 C18H7.12 Predicted to be located in nucleolus. WB:WBGene00189993 C49C3.21 Predicted to be located in membrane. WB:WBGene00189995 C06E7.88 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and Caappd based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and stavudine based on RNA-seq and microarray studies. WB:WBGene00194641 F47G3.4 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. WB:WBGene00194642 C25H3.17 Predicted to be located in membrane. WB:WBGene00194643 C48D1.9 Predicted to be located in membrane. WB:WBGene00194644 ZK795.6 Enriched in rect_D; rect_VL; rect_VR; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq studies. Is affected by multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00194645 Y105C5A.1269 Predicted to be located in membrane. WB:WBGene00194646 Y105C5A.1270 Predicted to be located in membrane. WB:WBGene00194647 Y51H4A.935 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Zidovudine; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00194649 Y57G11C.1130 Enriched in AFD; AIBL; AIBR; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and clk-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Ethanol; Rifampin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF1179 and Protein of unknown function (DUF1179). WB:WBGene00194650 C36A4.14 Enriched in AVK; intestine; and sensory neurons based on RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; stavudine; and Psoralens based on RNA-seq studies. WB:WBGene00194651 C33D9.13 Enriched in several structures, including ABalpapaap; ABarappaap; ABplpapapa; RMED; and interfacial epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by nineteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and bisphenol S based on RNA-seq and microarray studies. WB:WBGene00194652 F15H9.8 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including hsf-1; clk-1; and unc-30 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00194653 F36H2.6 Predicted to be located in membrane. WB:WBGene00194654 M05B5.7 Predicted to be located in membrane. WB:WBGene00194656 T05F1.15 Enriched in PLML; PLMR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by dpy-21; alg-1; and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00194657 T07D10.10 Is affected by several genes including daf-16; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by six chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00194658 R09E10.13 Enriched in ADE sheath cell and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by nine chemicals including tryptophan; Sodium Chloride; and allantoin based on microarray and RNA-seq studies. WB:WBGene00194659 linc-1 Is affected by several genes including rrf-3; cep-1; and cat-2 based on RNA-seq studies. Is affected by Alovudine; stavudine; and Tamoxifen based on RNA-seq studies. WB:WBGene00194660 W09C5.12 Enriched in arcade cell and pharyngeal-intestinal valve cell based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and csr-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Alovudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domain: Leucine-rich repeat domain superfamily. WB:WBGene00194661 Y57G11C.1131 Enriched in intestine based on single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-21; and sin-3 based on RNA-seq and microarray studies. WB:WBGene00194663 F38B2.6 Enriched in amphid sheath cell; anterior spermatheca; posterior spermatheca; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including rotenone; manganese chloride; and sodium arsenite based on RNA-seq studies. WB:WBGene00194664 K09E9.7 Enriched in AVK; amphid neurons; germ line; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including hsp-6; unc-30; and csr-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Rifampin; antimycin; and cholesterol based on RNA-seq studies. WB:WBGene00194665 ZK822.8 Is affected by several genes including daf-2; hsf-1; and sod-2 based on RNA-seq and microarray studies. Is affected by antimycin and cadmium based on RNA-seq studies. WB:WBGene00194666 Y57G11C.1132 Enriched in male based on RNA-seq studies. Is affected by dpy-21; daf-2; and nhr-42 based on RNA-seq and microarray studies. WB:WBGene00194667 Y105C5A.1271 Enriched in RID and RIG based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including methylmercury hydroxide; Rifampin; and Psoralens based on RNA-seq studies. WB:WBGene00194668 C08F11.116 Is affected by several genes including daf-16; cep-1; and hmg-3 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00194669 ZK1251.15 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00194670 K07E3.9 Enriched in ABalapaaaa; ABalappapa; amphid neurons; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by twelve chemicals including rotenone; multi-walled carbon nanotube; and allantoin based on RNA-seq and microarray studies. WB:WBGene00194672 Y116A8C.463 Enriched in coelomocyte based on single-cell RNA-seq studies. Is affected by hpl-2; hmg-3; and hlh-26 based on RNA-seq studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00194673 ZK593.11 Enriched in neurons based on RNA-seq studies. Is affected by kri-1 and lbp-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00194674 F23D12.11 Enriched in excretory cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on proteomic; RNA-seq; and microarray studies. Is affected by twenty-two chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00194675 Y60A9A.3 Enriched in germ line based on RNA-seq studies. Is affected by several genes including clk-1; hpl-2; and dpy-21 based on RNA-seq and microarray studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00194676 Y43F8B.21 Is affected by rrf-3 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00194677 D1054.19 Enriched in hypodermis and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00194678 R10D12.18 Is affected by several genes including cep-1; unc-30; and hpl-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00194679 T26C11.9 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by bisphenol A; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00194680 Y17D7C.6 Enriched in several structures, including ABalaapppa; ABalaappppa; neurons; rectal epithelial cell; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; sek-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00194681 F40D4.16 Enriched in AFD based on RNA-seq studies. Is affected by several genes including rrf-3; tph-1; and pgl-1 based on RNA-seq studies. Is affected by antimycin and paraquat based on RNA-seq studies. WB:WBGene00194682 F40D4.17 Enriched in several structures, including ABplpaaaaa; ABplpppaaa; ABprpaaaaa; AVH; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and ced-3 based on RNA-seq studies. Is affected by five chemicals including rotenone; manganese chloride; and allantoin based on RNA-seq studies. WB:WBGene00194683 T20G5.15 Is affected by several genes including eat-2; pgl-1; and cat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00194684 Y48A6B.14 Enriched in ASIL and ASIR based on single-cell RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by Rifampin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00194686 Y49A3A.6 Is affected by lem-2; emr-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00194687 F57C12.6 Is affected by several genes including skn-1; hsf-1; and elt-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including mianserin; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00194689 Y38H6C.24 Predicted to be located in membrane. WB:WBGene00194690 T05D4.6 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00194691 ZK1098.12 Predicted to be located in membrane. WB:WBGene00194692 T02C12.5 Enriched in intestine and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including clk-1; isp-1; and lin-15B based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00194695 B0462.5 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eighteen chemicals including methylmercury hydroxide; bisphenol A; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00194696 EEED8.18 Enriched in g2L and g2R based on single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including stavudine; Rifampin; and metformin based on RNA-seq and microarray studies. WB:WBGene00194697 F59A3.13 Predicted to be located in membrane. WB:WBGene00194698 F49D11.11 Predicted to be located in membrane. WB:WBGene00194699 Y43F8B.22 Enriched in ASER; G2; PLM; and W cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies. WB:WBGene00194700 B0025.5 Predicted to be located in membrane. WB:WBGene00194701 Y23H5B.12 Predicted to be located in membrane. WB:WBGene00194702 C32E8.12 Enriched in AVG; CAN; RIM; and command interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00194703 F26B1.8 Enriched in intestine; seam cell; sperm; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on RNA-seq and microarray studies. Is affected by twenty-five chemicals including Ethanol; rotenone; and manganese chloride based on RNA-seq and microarray studies. WB:WBGene00194704 T07H3.8 Is affected by several genes including clk-1; aak-2; and dpy-21 based on microarray and RNA-seq studies. WB:WBGene00194706 C53A5.16 Predicted to enable nucleotidyltransferase activity. Predicted to be involved in mRNA polyadenylation. WB:WBGene00194707 C53A5.17 Predicted to enable tRNA (guanine-N1-)-methyltransferase activity. Predicted to be involved in mitochondrial tRNA methylation and tRNA N1-guanine methylation. Predicted to be located in mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 26. Is an ortholog of human TRMT5 (tRNA methyltransferase 5). WB:WBGene00194708 Y36E3A.2 Predicted to be located in membrane. WB:WBGene00194710 mks-2 Involved in non-motile cilium assembly and protein localization to ciliary transition zone. Located in ciliary transition zone. Human ortholog(s) of this gene implicated in Joubert syndrome 2 and Meckel syndrome 2. Is an ortholog of human TMEM216 (transmembrane protein 216). WB:WBGene00194711 D2062.13 Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00194712 T11F9.21 Predicted to be located in membrane. WB:WBGene00194713 F19B10.13 Enriched in several structures, including ABalapapapa; ABalapppapa; coelomocyte; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including multi-walled carbon nanotube; Cadmium Chloride; and procyanidin based on RNA-seq and microarray studies. WB:WBGene00194714 ZC204.17 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00194715 T25E12.16 Predicted to be located in membrane. WB:WBGene00194716 ZK637.18 Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00194717 ZC239.22 Enriched in intestine and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including methylmercury hydroxide; 1-methylnicotinamide; and Alovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00194725 T16H12.13 Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. WB:WBGene00194726 R13A5.15 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00194727 C18D11.10 Predicted to be involved in innate immune response. WB:WBGene00194729 ZK783.7 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; AVE; and nerve ring neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on microarray and RNA-seq studies. Is affected by Rifampin based on RNA-seq studies. WB:WBGene00194730 C29E4.17 Predicted to be located in membrane. WB:WBGene00194731 Y39A1A.27 Enriched in muscle cell; neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on RNA-seq studies. Is affected by seven chemicals including stavudine; Zidovudine; and Rifampin based on RNA-seq studies. WB:WBGene00194733 Y41C4A.21 Is affected by several genes including daf-2; aak-2; and unc-30 based on RNA-seq and microarray studies. Is affected by Doxycycline; Tamoxifen; and paraquat based on RNA-seq studies. Is predicted to encode a protein with the following domains: Protein SUP-1-like and Protein of unknown function (DUF2650). WB:WBGene00194734 nsph-4.3 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by daf-2; eat-2; and sir-2.1 based on microarray studies. Is affected by resveratrol and Acrylamide based on microarray studies. Is predicted to encode a protein with the following domain: Cytosolic motility protein. WB:WBGene00194735 Y82E9BL.19 Is affected by several genes including eat-2; lin-35; and lin-15B based on RNA-seq studies. Is affected by six chemicals including tryptophan; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain. WB:WBGene00194737 Y50D7A.13 Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and carcinoma (multiple). Is an ortholog of human MMP2 (matrix metallopeptidase 2); MMP23B (matrix metallopeptidase 23B); and MMP9 (matrix metallopeptidase 9). WB:WBGene00194738 Y46E12A.5 Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00194742 F37C12.21 Enriched in AFD; ASER; PLM; and intestine based on RNA-seq studies. Is affected by several genes including daf-16; elt-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00194744 Y38H6C.25 Is affected by several genes including eat-2; clk-1; and pgl-1 based on microarray; RNA-seq; and proteomic studies. Is affected by metformin and Sirolimus based on RNA-seq studies. WB:WBGene00194746 pals-20 Enriched in intestine based on RNA-seq studies. Is affected by several genes including hsf-1; elt-2; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including stavudine; atracurium; and bortezomib based on RNA-seq studies. WB:WBGene00194747 H05C05.4 Predicted to be located in membrane. WB:WBGene00194748 F56F3.7 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including eat-2; cep-1; and alg-1 based on RNA-seq and microarray studies. Is affected by five chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00194759 Y113G7A.17 Is affected by kri-1; mpk-2; and etr-1 based on RNA-seq studies. WB:WBGene00194768 Y50E8A.19 Is affected by several genes including daf-16; daf-12; and hsf-1 based on RNA-seq studies. WB:WBGene00194769 Y32B12C.5 Is affected by several genes including daf-2; glp-1; and rrf-3 based on RNA-seq studies. Is affected by six chemicals including D-glucopyranose; Cadmium Chloride; and metformin based on RNA-seq and microarray studies. WB:WBGene00194771 F32F2.3 Is affected by several genes including daf-2; dpy-21; and klf-1 based on RNA-seq and microarray studies. WB:WBGene00194780 C12D8.20 Predicted to be located in membrane. WB:WBGene00194783 K03B8.14 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00194784 T11F9.22 Enriched in MC neuron; MCL; and MCR based on single-cell RNA-seq studies. Is affected by several genes including hpl-2; nhl-2; and cfp-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00194785 C52E4.12 Enriched in sensory neurons and in male based on RNA-seq studies. Is affected by several genes including eat-2; dpy-21; and nhl-2 based on RNA-seq and microarray studies. Is affected by cholesterol based on RNA-seq studies. WB:WBGene00194786 ZC455.13 No description available WB:WBGene00194787 T16G1.13 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Ethanol; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00194788 R02D5.10 Enriched in intestine and in male based on RNA-seq studies. Is affected by several genes including rrf-3; pgl-1; and lin-29 based on RNA-seq studies. Is affected by five chemicals including antimycin; Cry5B; and cholesterol based on RNA-seq and microarray studies. WB:WBGene00194792 F32F2.2 Is affected by daf-16; adr-1; and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00194793 W04G3.13 Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; clk-1; and nhr-49 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00194794 F45B8.5 Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including hsf-1; pgl-1; and isp-1 based on RNA-seq studies. Is affected by nine chemicals including rotenone; manganese chloride; and stavudine based on RNA-seq studies. WB:WBGene00194795 F42F12.14 Enriched in FLPL; FLPR; hypodermis; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; npr-1; and unc-70 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00194799 Y70C5A.4 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00194800 linc-83 Enriched in intestine based on RNA-seq studies. Is affected by several genes including cep-1; hsp-6; and atfs-1 based on RNA-seq studies. Is affected by graphene oxide; antimycin; and cadmium based on RNA-seq studies. WB:WBGene00194801 Y6G8.16 Enriched in PVT; neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain. WB:WBGene00194802 mir-1832.2 No description available WB:WBGene00194803 C25F9.16 Enriched in AIML; AIMR; head mesodermal cell; and muscle cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by eleven chemicals including multi-walled carbon nanotube; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00194804 mir-2207 Is affected by hrpk-1 based on RNA-seq studies. WB:WBGene00194805 mir-2210 Is affected by several genes including alg-1; alg-2; and alg-5 based on RNA-seq studies. Is affected by four chemicals including nicotine; multi-walled carbon nanotube; and graphene oxide based on quantitative PCR; RNA-seq; and microarray studies. WB:WBGene00194806 mir-2211 Enriched in sensory neurons based on RNA-seq studies. Is affected by alg-5 based on RNA-seq studies. WB:WBGene00194807 mir-2215 Is affected by alg-5 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR studies. WB:WBGene00194808 mir-2216 Is affected by alg-1; alg-2; and alg-5 based on RNA-seq studies. Is affected by nicotine and multi-walled carbon nanotube based on quantitative PCR and RNA-seq studies. WB:WBGene00194809 mir-2218.1 Is affected by alg-5 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR and RNA-seq studies. WB:WBGene00194810 mir-2218.2 Is affected by nicotine and glycine based on quantitative PCR and RNA-seq studies. WB:WBGene00194811 F22E10.6 Is affected by several genes including daf-2; let-418; and chd-3 based on RNA-seq and microarray studies. WB:WBGene00194812 F19B2.12 Enriched in AVK and head mesodermal cell based on RNA-seq studies. Is affected by several genes including eat-2; clk-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; manganese chloride; and allantoin based on RNA-seq studies. WB:WBGene00194814 linc-34 Is affected by several genes including daf-16; pgl-1; and cep-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and paraquat based on RNA-seq studies. WB:WBGene00194815 Y43F8B.23 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including glp-1; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including Sodium Chloride; tert-Butylhydroperoxide; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00194816 ZK616.61 Enriched in AFD and in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including tryptophan; rotenone; and manganese chloride based on microarray and RNA-seq studies. WB:WBGene00194821 dmsr-16 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00194822 mir-2208.1 Is affected by alg-5 and pry-1 based on RNA-seq studies. Is affected by nicotine based on RNA-seq studies. WB:WBGene00194823 mir-2208.2 Is affected by several genes including alg-1; alg-2; and alg-5 based on RNA-seq studies. WB:WBGene00194824 mir-2209.1 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine based on quantitative PCR studies. WB:WBGene00194825 mir-2209.2 Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00194826 mir-2209.3 Is affected by alg-2 and alg-5 based on RNA-seq studies. WB:WBGene00194827 mir-2213 Is affected by alg-5 based on RNA-seq studies. WB:WBGene00194828 mir-2214 Is affected by several genes including glp-4; prg-1; and alg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and graphene oxide based on RNA-seq studies. WB:WBGene00194829 mir-2217.1 Is affected by alg-1; alg-2; and alg-5 based on RNA-seq studies. Is affected by graphene oxide and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00194830 mir-2219 Is affected by alg-1; alg-2; and alg-5 based on RNA-seq studies. WB:WBGene00194831 mir-2220 Is affected by alg-5 based on RNA-seq studies. Is affected by nicotine; multi-walled carbon nanotube; and sanguinarine based on quantitative PCR and RNA-seq studies. WB:WBGene00194832 Y73B6BL.270 Enriched in M cell; neurons; and pharyngeal neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by dpy-21; ins-11; and damt-1 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00194833 F17E9.15 Enriched in intestine and in male based on RNA-seq and microarray studies. Is affected by several genes including sir-2.1; csr-1; and hpl-2 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00194834 H06H21.36 Is affected by daf-3 based on RNA-seq studies. WB:WBGene00194835 Y17G9B.11 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and alg-1 based on RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00194836 C25H3.18 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and atfs-1 based on RNA-seq studies. Is affected by four chemicals including rotenone; stavudine; and Rifampin based on RNA-seq studies. WB:WBGene00194839 C01B10.44 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by Doxycycline; paraquat; and Ketamine based on RNA-seq studies. WB:WBGene00194840 mir-2212 Is affected by several genes including glp-4; alg-1; and alg-2 based on RNA-seq studies. Is affected by nicotine and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00194841 C44C10.13 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00194842 W10G6.5 Is affected by rpn-10 and hpl-2 based on RNA-seq studies. WB:WBGene00194843 F58E2.11 Is affected by daf-2 and eat-2 based on microarray studies. Is affected by multi-walled carbon nanotube and paraquat based on RNA-seq studies. WB:WBGene00194844 Y55F3C.13 Is affected by smg-2 based on RNA-seq studies. WB:WBGene00194847 F19C6.8 Enriched in AVK based on RNA-seq studies. Is affected by several genes including daf-2; nhr-49; and alg-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle and paraquat based on microarray and RNA-seq studies. WB:WBGene00194848 T27D12.6 Enriched in several structures, including ASER; Caaaaa; Caaaap; Caaapa; and gonadal sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq studies. Is affected by eight chemicals including stavudine; Sodium Chloride; and Psoralens based on RNA-seq studies. WB:WBGene00194849 K09A9.8 Enriched in ABaraapapaa; ABaraapapp; ABaraapppaa; ABaraapppp; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00194850 F44F4.15 Predicted to be located in membrane. WB:WBGene00194851 K07C10.3 Enriched in head mesodermal cell and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cep-1; atfs-1; and set-2 based on RNA-seq studies. Is affected by Zidovudine; paraquat; and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00194852 T28A8.8 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including rotenone; manganese chloride; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain. WB:WBGene00194853 Y111B2A.29 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00194854 Y111B2A.30 Is affected by ins-11; adr-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00194855 Y75B8A.44 Predicted to be located in membrane. WB:WBGene00194856 K11D9.5 Is affected by cep-1; daf-2; and etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and paraquat based on microarray and RNA-seq studies. WB:WBGene00194861 H04D03.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on RNA-seq studies. Is affected by four chemicals including stavudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00194864 Y66A7A.9 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; ABalappppaa; and ABalppapppa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including Ethanol; manganese chloride; and antimycin based on RNA-seq and microarray studies. WB:WBGene00194865 F53A2.10 Is affected by cep-1; tdp-1; and adr-1 based on RNA-seq studies. WB:WBGene00194866 Y41C4A.22 Enriched in ASG; ASGL; ASGR; PHB; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including alg-1; met-2; and hpl-2 based on RNA-seq studies. WB:WBGene00194867 W09C2.10 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00194868 M03C11.9 Predicted to be located in membrane. WB:WBGene00194869 K01A6.8 Enriched in AMshL; AMshR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and nhr-49 based on RNA-seq and microarray studies. Is affected by five chemicals including procyanidin; Cadmium Chloride; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00194870 F53A2.11 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. WB:WBGene00194871 R107.9 No description available WB:WBGene00194876 flr-6 No description available WB:WBGene00194877 flr-7 No description available WB:WBGene00194883 B0496.11 Enriched in amphid sheath cell; anal sphincter muscle; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00194884 Y48B6A.17 Is affected by several genes including cep-1; puf-8; and ins-11 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00194885 Y57G11C.1133 No description available WB:WBGene00194886 C05B5.12 Enriched in amphid sheath cell and in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00194888 K10H10.13 Is affected by several genes including daf-2; csr-1; and etr-1 based on RNA-seq and microarray studies. Is affected by Ag nanoparticles and bortezomib based on RNA-seq studies. WB:WBGene00194890 C01B9.4 Is affected by several genes including daf-2; csr-1; and jmjd-3.1 based on RNA-seq and microarray studies. WB:WBGene00194891 Y6D1A.3 Enriched in male gonad based on microarray studies. Is affected by several genes including daf-16; prg-1; and fbf-1 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; cadmium; and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00194892 dsb-2 Located in condensed chromosome. Expressed in germ cell and gonad. WB:WBGene00194894 T05B4.14 Predicted to be located in membrane. WB:WBGene00194895 ZK105.11 Predicted to be located in membrane. WB:WBGene00194896 W02H5.11 Predicted to be located in membrane. WB:WBGene00194898 C17B7.14 Is affected by several genes including sir-2.1; aak-2; and egl-9 based on RNA-seq and microarray studies. WB:WBGene00194902 Y39H10B.3 Is affected by several genes including skn-1; hsf-1; and elt-2 based on RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00194905 Y53F4B.51 Enriched in several structures, including ABarpapaapp; AIA; RMD; cholinergic neurons; and command interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including atfs-1; nuo-6; and unc-70 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00194906 Y53C12A.11 Enriched in germ line and intestine based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and dpy-10 based on RNA-seq and microarray studies. Is affected by ten chemicals including manganese chloride; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00194907 E02H4.8 Enriched in neurons based on RNA-seq studies. Is affected by several genes including let-60; sir-2.1; and sek-1 based on RNA-seq and microarray studies. Is affected by rotenone based on RNA-seq studies. WB:WBGene00194908 F22F7.8 Enriched in AFD; intestine; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including 1-methylnicotinamide; stavudine; and Psoralens based on RNA-seq studies. WB:WBGene00194909 F41E6.17 Enriched in head mesodermal cell and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; lin-35; and set-2 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00194910 ZC404.15 Predicted to be located in membrane. WB:WBGene00194912 ZK856.18 Enriched in MSpppaaa; head mesodermal cell; intestine; and in male based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including allantoin; Sirolimus; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00194913 Y105C5A.1272 Enriched in AFD; PLML; PLMR; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; alg-1; and egl-43 based on RNA-seq and microarray studies. WB:WBGene00194914 F44D12.16 Enriched in male based on RNA-seq studies. Is affected by several genes including let-60; sir-2.1; and hpl-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Tamoxifen; resveratrol; and Acrylamide based on RNA-seq and microarray studies. WB:WBGene00194915 JC8.16 Predicted to be located in membrane. WB:WBGene00194916 F35D2.6 Enriched in anterior arcade cell; arc ant V; and excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and pmk-1 based on RNA-seq and microarray studies. Is affected by six chemicals including methylmercury hydroxide; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00194917 Y45F10B.59 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and ABarpppapa based on single-cell RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and csr-1 based on RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00194918 K08D8.9 Predicted to be located in membrane. WB:WBGene00194919 K08D8.10 Predicted to be located in membrane. WB:WBGene00194920 H12I19.115 Is affected by egl-43 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00194921 ZK742.7 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00194922 F13E9.19 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; tph-1; and csr-1 based on RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00194923 linc-121 Is affected by chd-3; let-418; and sin-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00194924 Y51H4A.936 Is affected by Sirolimus based on microarray studies. WB:WBGene00194925 K08D8.11 Is affected by several genes including daf-2; eat-2; and elt-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00194926 K08D8.12 Predicted to be located in membrane. WB:WBGene00194927 Y51H4A.937 No description available WB:WBGene00194928 ZC513.14 Enriched in ABplpappaa based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sid-1 based on RNA-seq studies. Is affected by four chemicals including tryptophan; iron oxide nanoparticle; and Cry5B based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00194929 Y105C5B.1413 Is affected by several genes including daf-2; dpy-21; and set-2 based on RNA-seq and microarray studies. Is affected by tryptophan and stavudine based on microarray and RNA-seq studies. WB:WBGene00194930 Y73F8A.1159 Predicted to enable hydrolase activity. WB:WBGene00194931 Y105C5A.1273 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00194932 F54F7.11 Is affected by several genes including hsp-6; mdt-15; and adr-1 based on RNA-seq studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00194933 T12A7.10 Enriched in male based on RNA-seq studies. Is affected by several genes including tph-1; csr-1; and tax-6 based on RNA-seq and microarray studies. Is affected by five chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00194934 ZK809.9 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in membrane. Is an ortholog of human PXYLP1 (2-phosphoxylose phosphatase 1). WB:WBGene00194935 M02G9.4 Enriched in ASER and in male based on RNA-seq studies. Is affected by several genes including skn-1; eat-2; and pgl-1 based on RNA-seq studies. Is affected by five chemicals including Cry5B; cholesterol; and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00194939 C01B9.5 Is affected by several genes including daf-2; unc-30; and smg-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube and atracurium based on RNA-seq studies. WB:WBGene00194940 C34C6.9 Enriched in K cell and K' cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; xpf-1; and sin-3 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00194945 C32H11.16 Is affected by dpy-21 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00194951 Y105C5A.1274 Enriched in intestine based on microarray studies. Is affected by several genes including sir-2.1; lin-35; and nhr-49 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00194952 ZK666.14 Predicted to be located in membrane. WB:WBGene00194955 F37H8.6 Enriched in AFD; anterior arcade cell; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including eat-2; sek-1; and alg-1 based on RNA-seq and microarray studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00194957 Y116A8C.465 Is affected by several genes including daf-2; aak-2; and unc-30 based on microarray and RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00194981 Y49E10.30 Enriched in several structures, including ABalaaaala; ABalaapaaa; AFD; MC neuron; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by Alovudine; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00194982 Y17D7B.10 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapapapa; AUA; and ciliated neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; aak-2; and unc-30 based on RNA-seq and microarray studies. Is affected by stavudine; antimycin; and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00194983 T25B2.4 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00194984 R102.15 Is affected by lem-2; hsf-1; and etr-1 based on RNA-seq studies. WB:WBGene00194985 Y25C1A.14 Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by nine chemicals including 1-methylnicotinamide; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00194986 pigb-1 Predicted to enable alpha-1,2-mannosyltransferase activity. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 80. Is an ortholog of human PIGB (phosphatidylinositol glycan anchor biosynthesis class B). WB:WBGene00194987 T14B4.10 No description available WB:WBGene00194988 B0213.21 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00194989 B0213.22 No description available WB:WBGene00194990 B0213.23 Is affected by dpy-21 and hmg-3 based on RNA-seq studies. Is affected by CGP37157 based on RNA-seq studies. WB:WBGene00194991 B0213.24 Is affected by hmg-3 based on RNA-seq studies. Is affected by fluvastatin based on RNA-seq studies. WB:WBGene00194992 H27M09.6 Is affected by sftb-1 based on RNA-seq studies. WB:WBGene00194993 T27E4.11 Enriched in germ line based on RNA-seq studies. Is affected by several genes including lag-1; dlc-1; and sftb-1 based on RNA-seq studies. WB:WBGene00194994 T27E4.12 Is affected by alg-1 and sftb-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00194995 C05G6.4 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00194996 Y69A2AR.36 Is affected by cep-1 and sftb-1 based on RNA-seq studies. WB:WBGene00194997 F42C5.12 Is affected by several genes including pgl-1; glh-1; and hpl-2 based on RNA-seq studies. WB:WBGene00194998 C16C4.18 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalpapaap; AFD; and RMED based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by rotenone; stavudine; and paraquat based on RNA-seq studies. WB:WBGene00194999 B0205.15 No description available WB:WBGene00195000 F54D8.7 Is affected by adr-1; mett-10; and etr-1 based on RNA-seq studies. WB:WBGene00195001 Y17G9A.85 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00195002 T08B6.62 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00195003 Y46C8AL.11 Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and hpl-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00195004 K08D12.8 Enriched in arcade cell and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00195005 ZK809.10 Is affected by several genes including daf-2; cep-1; and daf-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00195006 C35B1.9 Is affected by several genes including eat-2; sir-2.1; and set-2 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00195007 mir-5595 Is affected by alg-5 based on RNA-seq studies. WB:WBGene00195008 mir-4813 Expressed in pharynx. WB:WBGene00195009 F17E9.16 Enriched in ABalpapaap; ABarappaap; ADEL; ADER; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; csr-1; and xpf-1 based on RNA-seq and microarray studies. Is affected by Ketamine based on RNA-seq studies. WB:WBGene00195010 Y37E11AL.12 Predicted to be located in membrane. WB:WBGene00195011 ZK180.8 Enriched in K cell; K' cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; set-2; and fzo-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and paraquat based on RNA-seq studies. WB:WBGene00195012 Y38C1BA.4 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00195014 H05L03.5 No description available WB:WBGene00195015 H05L03.6 No description available WB:WBGene00195016 srpr-2.1 Enriched in germ line and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by manganese chloride and paraquat based on RNA-seq studies. WB:WBGene00195017 srpr-2.2 Enriched in NSM and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and unc-30 based on RNA-seq and microarray studies. Is affected by Ethanol; Tunicamycin; and paraquat based on RNA-seq studies. WB:WBGene00195018 srpr-3 Enriched in AVK based on RNA-seq studies. Is affected by several genes including pgl-1; alg-1; and glh-1 based on RNA-seq studies. WB:WBGene00195019 Y59H11AR.8 Enriched in AFD based on RNA-seq studies. WB:WBGene00195020 Y59H11AR.9 Is affected by several genes including lem-2; emr-1; and meg-3 based on RNA-seq studies. WB:WBGene00195021 K08F11.7 No description available WB:WBGene00195022 F39E9.15 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00195023 F39E9.16 Is affected by cat-2 and tdc-1 based on RNA-seq studies. WB:WBGene00195024 F39E9.17 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00195025 F39E9.18 Is affected by several genes including sir-2.1; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube and paraquat based on RNA-seq studies. WB:WBGene00195026 F39E9.19 Enriched in intestine based on microarray studies. Is affected by lin-14 and lin-4 based on microarray studies. WB:WBGene00195027 F39E9.20 Enriched in intestine based on microarray studies. Is affected by lin-14 and lin-4 based on microarray studies. WB:WBGene00195028 F39E9.21 Enriched in AFD and intestine based on RNA-seq and microarray studies. Is affected by lin-14 and lin-4 based on microarray studies. WB:WBGene00195029 Y37E11B.11 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00195030 F10E7.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00195031 Y37E3.23 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00195032 Y37E3.24 Is affected by several genes including tph-1; pgl-1; and cat-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00195033 Y37E3.25 Enriched in AFD based on RNA-seq studies. Is affected by several genes including tph-1; pgl-1; and cat-2 based on RNA-seq studies. WB:WBGene00195034 F40G9.20 Is affected by several genes including pgl-1; daf-1; and daf-3 based on RNA-seq studies. Is affected by Cadmium Chloride based on RNA-seq studies. WB:WBGene00195035 Y46H3C.9 No description available WB:WBGene00195036 T08D2.10 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00195037 F59H5.4 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00195038 F59H6.13 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00195039 K08A2.9 No description available WB:WBGene00195040 K08A2.10 Enriched in AFD based on RNA-seq studies. Is affected by several genes including sek-1; pgl-1; and glh-1 based on RNA-seq studies. WB:WBGene00195043 Y57G11C.1135 Enriched in muscle cell and neurons based on RNA-seq studies. Is affected by several genes including cep-1; alg-1; and dpy-21 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195045 W05F2.8 Enriched in PLML; PLMR; neurons; and pm8 based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by metformin and Doxycycline based on RNA-seq studies. WB:WBGene00195046 F42A9.11 Enriched in MSpppaaa; arcade cell; head mesodermal cell; neurons; and pharyngeal-intestinal valve cell based on RNA-seq and single-cell RNA-seq studies. Is affected by dlc-1 and egl-43 based on RNA-seq studies. WB:WBGene00195048 K08D10.13 Is affected by several genes including set-2; let-418; and chd-3 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like. WB:WBGene00195049 CC8.3 Enriched in ciliated neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by dpy-21 and set-2 based on RNA-seq studies. Is affected by Ag nanoparticles based on RNA-seq studies. WB:WBGene00195050 T22D1.17 Predicted to be located in membrane. WB:WBGene00195051 T22D1.18 Predicted to be located in membrane. WB:WBGene00195056 C45E1.5 Is affected by several genes including sir-2.1; mrps-5; and hlh-26 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00195057 B0261.9 Is affected by several genes including eat-2; hpl-2; and swsn-1 based on RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00195058 C54E10.7 Enriched in ASER and neurons based on RNA-seq studies. Is affected by fzo-1 and fbf-1 based on RNA-seq and microarray studies. Is affected by Chlorpyrifos; Diazinon; and Sirolimus based on microarray studies. WB:WBGene00195060 linc-14 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including skn-1; daf-12; and rrf-3 based on RNA-seq studies. Is affected by graphene oxide; paraquat; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00195061 ZK228.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00195063 coa-1 Predicted to be involved in mitochondrial cytochrome c oxidase assembly and mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Is an ortholog of human COA1 (cytochrome c oxidase assembly factor 1). WB:WBGene00195064 F17C11.20 Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies. Is affected by bisphenol A and bisphenol S based on RNA-seq studies. WB:WBGene00195065 F20G2.9 Is affected by spt-16; pmt-2; and ikb-1 based on RNA-seq and microarray studies. Is affected by Cry5B based on microarray studies. WB:WBGene00195067 C04C3.9 Enriched in arcade cell; pharyngeal-intestinal valve cell; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including elt-2; nhl-2; and emb-4 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00195068 Y48G8AL.16 Enriched in AFD; AINL; and AINR based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and aak-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00195069 W03G9.10 Predicted to be located in membrane. WB:WBGene00195070 C16C8.20 Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to be part of cytosolic small ribosomal subunit. WB:WBGene00195071 C16C8.21 Is affected by several genes including daf-2; rrf-1; and unc-30 based on RNA-seq and microarray studies. Is affected by Ethanol and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Ubiquitin-like domain superfamily. WB:WBGene00195072 C16C8.22 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by cholesterol; paraquat; and Progesterone based on RNA-seq and microarray studies. WB:WBGene00195073 F02E11.7 Predicted to be located in membrane. WB:WBGene00195077 T24E12.13 Enriched in ABplaapappp; ABpraapappp; pm8; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00195081 C04F6.7 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00195084 C43C3.4 Enriched in several structures, including ABaraapapaa; MSpppaaa; enteric muscle; ganglia; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Alovudine; and stavudine based on RNA-seq and microarray studies. WB:WBGene00195086 F21C10.13 Predicted to be located in membrane. WB:WBGene00195093 Y59E9AL.36 Predicted to enable RNA binding activity. WB:WBGene00195117 T13F3.10 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00195142 M110.10 Predicted to be located in membrane. WB:WBGene00195143 nlp-78 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00195144 C16D2.3 Is affected by several genes including rrf-3; unc-30; and nhr-8 based on RNA-seq and microarray studies. Is affected by cholesterol based on RNA-seq studies. WB:WBGene00195145 ZK666.15 Predicted to be located in membrane. WB:WBGene00195146 F54D5.17 Enriched in ABaraappaa; muscle cell; rectal muscle; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on RNA-seq studies. Is affected by five chemicals including tryptophan; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00195147 F14E5.8 Enriched in several structures, including ABplpppaaa; ABprpppaaa; ASER; MSaapapa; and MSpapapa based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and isp-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including manganese chloride; multi-walled carbon nanotube; and Zidovudine based on RNA-seq studies. WB:WBGene00195148 W02B12.16 Enriched in male based on RNA-seq studies. Is affected by several genes including eat-2; tph-1; and csr-1 based on RNA-seq studies. Is affected by six chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq studies. WB:WBGene00195149 F26H11.8 Is affected by hpl-2 and set-2 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00195150 Y81G3A.6 Predicted to be located in membrane. WB:WBGene00195151 F53H2.4 Enriched in germ line and sensory neurons based on RNA-seq studies. Is affected by several genes including prg-1; sma-2; and sma-4 based on RNA-seq studies. WB:WBGene00195154 F13A2.10 Enriched in accessory cell; lateral ganglion; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00195155 W04A8.9 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including pgl-1; sma-3; and glh-1 based on RNA-seq studies. Is affected by six chemicals including rotenone; Alovudine; and Psoralens based on RNA-seq studies. WB:WBGene00195157 C12D8.21 Enriched in ABalapppaa; body wall muscle cell from MS lineage; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including alg-1; met-2; and nuo-6 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00195158 F26F2.11 Is affected by ifo-1; swsn-1; and hlh-26 based on microarray and RNA-seq studies. WB:WBGene00195159 T04C12.14 Enriched in neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including sek-1; dpy-21; and set-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00195160 Y47D7A.17 Is affected by several genes including hpl-2; dpy-21; and nhl-2 based on RNA-seq and microarray studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00195164 K12B6.11 Enriched in ABplpaaaap; ABprpaaaap; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by fourteen chemicals including Tunicamycin; multi-walled carbon nanotube; and Zidovudine based on RNA-seq studies. WB:WBGene00195165 F57G4.11 Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including metformin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species and FTH domain. WB:WBGene00195166 W05B10.6 Predicted to be located in membrane. WB:WBGene00195168 T13C5.9 Is affected by several genes including rrf-3; aak-2; and isp-1 based on RNA-seq studies. Is affected by Rifampin; allantoin; and antimycin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00195169 Y50D4A.6 Enriched in several structures, including ABplapaaap; ABplppaaaap; ABprppaaaap; head mesodermal cell; and head neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on RNA-seq studies. Is affected by seven chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq studies. WB:WBGene00195170 linc-61 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and cadmium based on microarray and RNA-seq studies. WB:WBGene00195171 T09D3.9 Enriched in CEM; HOB; IL2 neuron; and ray neuron type B based on RNA-seq studies. Is affected by csr-1 based on RNA-seq studies. WB:WBGene00195172 K10G4.14 Is affected by several genes including cep-1; set-2; and adr-1 based on RNA-seq studies. WB:WBGene00195174 K08E5.6 Is affected by elt-2; elt-7; and smn-1 based on RNA-seq studies. WB:WBGene00195175 Y105E8A.36 Enriched in AVK and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and sma-2 based on RNA-seq and microarray studies. Is affected by rotenone and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00195176 Y43F8B.24 Enriched in AIZL; AIZR; head mesodermal cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including tryptophan; Zidovudine; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00195177 Y43F8B.25 Predicted to be located in membrane. WB:WBGene00195178 ZC581.10 Enriched in PVT; cholinergic neurons; head neurons; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including manganese chloride; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00195179 F48C1.11 Is affected by several genes including daf-16; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including tryptophan; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00195180 C41D11.10 Enriched in neurons and in male based on RNA-seq studies. Is affected by several genes including eat-2; tph-1; and csr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq studies. WB:WBGene00195181 F15H10.12 Is affected by several genes including lin-15B; dpy-21; and lin-37 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00195182 C17G10.10 Enriched in intestine and in male based on RNA-seq and microarray studies. Is affected by several genes including sir-2.1; hpl-2; and dpy-21 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00195183 R04A9.9 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalapaaaa; ABalappapa; and ABalapppaa based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including rotenone; manganese chloride; and Alovudine based on RNA-seq and microarray studies. WB:WBGene00195184 F19G12.8 Enriched in intestine; pharynx; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; elt-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by five chemicals including stavudine; bortezomib; and Atrazine based on RNA-seq and microarray studies. WB:WBGene00195185 F19G12.9 Predicted to be located in ribosome. WB:WBGene00195186 F19G12.10 Enriched in PLM and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and pgl-1 based on RNA-seq studies. Is affected by ten chemicals including Cadmium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00195188 F19G12.11 Enriched in several structures, including ABalaappppa; DVA; anal sphincter muscle; inner labial neurons; and lateral ganglion based on single-cell RNA-seq studies. Is affected by eat-2 based on RNA-seq studies. Is affected by Rifampin and Sirolimus based on RNA-seq studies. WB:WBGene00195189 ZC449.8 Enriched in arcade cell; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and npr-1 based on RNA-seq; microarray; and proteomic studies. Is affected by eight chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00195192 C54F6.16 Is affected by several genes including dpy-21; smg-2; and etr-1 based on RNA-seq studies. WB:WBGene00195208 W02H3.3 Enriched in neurons and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by set-2; nfki-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00195209 C07B5.8 Enriched in ABalpappaa; ABarapapaa; AFD; ASER; and RIS based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and hsp-6 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00195210 Y7A5A.13 Predicted to be located in membrane. WB:WBGene00195211 C34F6.12 Predicted to be located in membrane. WB:WBGene00195212 F09B12.7 Predicted to be located in membrane. WB:WBGene00195213 F11C1.9 Is affected by several genes including daf-2; dpy-21; and adr-2 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00195214 F11C1.10 Enriched in neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and dpy-21 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00195215 F55G7.5 Predicted to be located in membrane. WB:WBGene00195226 ZC404.16 Enriched in OLLL; OLLR; RIH; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; unc-30; and mep-1 based on RNA-seq studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00195227 Y71A12B.23 Enriched in male based on RNA-seq studies. Is affected by several genes including skn-1; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; antimycin; and Doxycycline based on RNA-seq studies. WB:WBGene00195228 Y71A12B.24 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00195229 Y71A12B.25 No description available WB:WBGene00195230 F36D1.13 No description available WB:WBGene00195231 F36D1.14 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00195232 F36D1.15 Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by pmt-2; daf-2; and daf-18 based on microarray and RNA-seq studies. WB:WBGene00195233 F31E9.11 Enriched in head mesodermal cell and intestine based on RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and eat-2 based on RNA-seq studies. Is affected by four chemicals including rotenone; antimycin; and paraquat based on RNA-seq and microarray studies. WB:WBGene00195234 C14C10.9 Is affected by dpy-21 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00195235 C47E8.12 Is affected by dpy-21; alg-1; and set-2 based on RNA-seq studies. WB:WBGene00195236 mir-356.2 Enriched in neurons based on RNA-seq studies. Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. WB:WBGene00195237 Y116F11B.18 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00195238 mir-4805 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and graphene oxide based on RNA-seq studies. WB:WBGene00195239 ZK1127.13 Predicted to be involved in RNA catabolic process. Predicted to be part of ribonuclease H2 complex. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Is an ortholog of human RNASEH2C (ribonuclease H2 subunit C). WB:WBGene00195240 Y39B6A.69 Enriched in ABplppppaa and ABprppppaa based on single-cell RNA-seq studies. Is affected by several genes including eat-2; nhr-49; and hpl-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00195241 Y113G7B.27 Enriched in AVG; PVT; excretory duct; and excretory pore based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; bisphenol A; and Psoralens based on RNA-seq studies. WB:WBGene00195242 Y113G7B.28 Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaapa; ABplpaapap; and ABprpaaapa based on single-cell RNA-seq studies. Is affected by eat-2; srbc-48; and npr-8 based on RNA-seq studies. WB:WBGene00195243 F46B3.23 Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in membrane. WB:WBGene00195244 F30A10.15 Predicted to be located in membrane. WB:WBGene00195245 T26A8.6 Is affected by several genes including daf-2; prg-1; and dlc-1 based on RNA-seq studies. WB:WBGene00195246 ZK546.19 Enriched in intestine based on microarray studies. Is affected by several genes including sir-2.1; nhr-49; and daf-18 based on RNA-seq and microarray studies. Is affected by paraquat and resveratrol based on RNA-seq and microarray studies. WB:WBGene00195247 F41D3.15 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195248 emc-5 Predicted to enable inorganic cation transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in Golgi apparatus; early endosome; and plasma membrane. Predicted to be part of EMC complex. Is an ortholog of human MMGT1 (membrane magnesium transporter 1). WB:WBGene00195250 C13C4.8 Predicted to be located in membrane. WB:WBGene00195252 K10D6.6 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00195253 H16D19.5 Enriched in germ line; sensory neurons; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on RNA-seq studies. Is affected by six chemicals including rotenone; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00195254 H16D19.6 Enriched in sensory neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including rrf-3; sek-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00195255 H16D19.7 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by Rifampin and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00195256 F25D1.8 Predicted to enable DNA binding activity. WB:WBGene00195257 W01A8.10 Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including multi-walled carbon nanotube; metformin; and Psoralens based on RNA-seq studies. WB:WBGene00195258 F11D5.8 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00195259 C16E9.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00195260 T27F7.5 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195261 F26A10.4 No description available WB:WBGene00195262 T22B7.9 No description available WB:WBGene00195263 F02E8.7 No description available WB:WBGene00195264 F14B8.8 No description available WB:WBGene00195265 F47B7.9 No description available WB:WBGene00195266 ZC132.10 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by elli-1 and adr-1 based on microarray and RNA-seq studies. WB:WBGene00195267 C45E5.53 Is affected by let-418 and hlh-26 based on RNA-seq studies. WB:WBGene00195268 C39F7.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195269 F49E10.8 No description available WB:WBGene00195270 T23F11.7 Is affected by set-2 based on RNA-seq studies. WB:WBGene00195271 F45H7.8 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195272 C33F10.15 No description available WB:WBGene00195273 K11E4.7 No description available WB:WBGene00195274 ZK617.7 Is affected by rnp-6 and etr-1 based on RNA-seq studies. Is affected by Tunicamycin and Oligosaccharides based on microarray studies. WB:WBGene00195275 ZK867.4 Is affected by cep-1; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00195276 T27E4.13 No description available WB:WBGene00195277 Y38H6C.26 No description available WB:WBGene00195278 F46G11.7 No description available WB:WBGene00195279 C05D2.12 No description available WB:WBGene00195280 Y67A10A.342 Is affected by tatn-1 based on RNA-seq studies. WB:WBGene00195281 M79.5 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00195282 Y43F8A.6 No description available WB:WBGene00195283 F27C8.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00195284 Y55H10A.3 No description available WB:WBGene00195285 T02E9.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00195286 C03E10.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00195287 B0495.11 No description available WB:WBGene00195288 C11D2.98 Enriched in neurons based on RNA-seq studies. WB:WBGene00195289 Y39G10AR.26 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195290 F14D12.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00195291 T06F4.4 No description available WB:WBGene00195292 Y47D3B.13 No description available WB:WBGene00195293 F56A4.13 Is affected by daf-2; ifo-1; and endu-2 based on microarray studies. WB:WBGene00195294 C32A3.4 No description available WB:WBGene00195295 F11D5.9 Is affected by cep-1; dlc-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195296 C08E8.12 No description available WB:WBGene00195297 T19D2.5 Is affected by daf-2 based on microarray studies. WB:WBGene00195298 F14F3.6 No description available WB:WBGene00195299 F11C1.11 No description available WB:WBGene00195300 ZC190.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195301 F12F6.12 No description available WB:WBGene00195302 ZK1131.2 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195303 Y22D7AR.16 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195304 ZC53.8 No description available WB:WBGene00195305 W05E10.7 No description available WB:WBGene00195306 K07C11.13 No description available WB:WBGene00195307 C31G12.5 No description available WB:WBGene00195308 ZK617.8 No description available WB:WBGene00195309 F59B8.5 Enriched in neurons based on RNA-seq studies. Is affected by several genes including prg-1; lem-2; and emr-1 based on RNA-seq and microarray studies. WB:WBGene00195310 ZK1086.5 Is affected by pmt-2 based on microarray studies. WB:WBGene00195311 M110.11 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00195312 C34H3.3 No description available WB:WBGene00195313 F47E1.8 Is affected by daf-2 based on microarray studies. WB:WBGene00195314 F40F12.10 Is affected by wdr-23 based on RNA-seq studies. WB:WBGene00195315 Y47H9C.16 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00195316 T03G11.12 No description available WB:WBGene00195317 T23G5.9 No description available WB:WBGene00195318 C18C4.11 No description available WB:WBGene00195319 R12A1.5 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195320 Y53H1C.4 No description available WB:WBGene00195321 C46F11.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195322 T06E4.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195323 B0432.16 No description available WB:WBGene00195324 F56E3.5 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195325 K04H4.8 Is affected by etr-1 based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00195326 T06H11.6 No description available WB:WBGene00195327 F11D5.10 No description available WB:WBGene00195328 C01B7.8 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by bcat-1 based on RNA-seq studies. WB:WBGene00195329 ZK512.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00195330 K08A8.4 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; adr-1; and camt-1 based on RNA-seq studies. WB:WBGene00195331 R10E12.3 Enriched in sensory neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00195332 C40C9.6 No description available WB:WBGene00195333 F54F12.3 Is affected by etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195334 F52E4.9 No description available WB:WBGene00195335 B0454.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195336 ZC581.11 No description available WB:WBGene00195337 C31H2.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00195338 T02E9.9 Is affected by set-2 based on RNA-seq studies. WB:WBGene00195339 H32C10.94 Enriched in neurons based on RNA-seq studies. WB:WBGene00195340 M88.9 No description available WB:WBGene00195341 F54D5.18 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00195342 T19C4.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00195343 Y53C12A.12 No description available WB:WBGene00195344 ZK525.4 Enriched in neurons based on RNA-seq studies. Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00195345 F25F6.2 Is affected by daf-2 based on microarray studies. WB:WBGene00195346 W02H5.13 No description available WB:WBGene00195347 K03H9.5 Is affected by cep-1 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00195348 F25H8.8 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00195349 ZK622.6 Is affected by daf-2 based on microarray studies. WB:WBGene00195350 ZK973.12 Is affected by Tunicamycin based on microarray studies. WB:WBGene00195351 ZK40.3 No description available WB:WBGene00195352 C10G11.12 No description available WB:WBGene00195353 Y73F8A.1160 No description available WB:WBGene00195354 ZK593.13 Enriched in neurons based on RNA-seq studies. Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00195355 Y92H12A.8 No description available WB:WBGene00195356 F57H12.10 No description available WB:WBGene00195357 F52E10.6 Is affected by cep-1; daf-2; and lpd-3 based on RNA-seq and microarray studies. WB:WBGene00195358 B0507.13 No description available WB:WBGene00195359 R07G3.10 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195360 K05B2.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00195361 C24E9.1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00195362 Y82E9BR.26 Enriched in neurons based on RNA-seq studies. WB:WBGene00195363 M01H9.6 Enriched in head mesodermal cell and neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00195364 M01G4.3 No description available WB:WBGene00195365 F45E4.15 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195366 C50F4.17 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195367 B0524.7 Is affected by several genes including daf-12; dpy-21; and lin-22 based on tiling array and RNA-seq studies. WB:WBGene00195368 F28F5.8 Is affected by cep-1 based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00195369 Y65B4BL.8 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00195370 F29B9.13 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. Is affected by cholesterol based on RNA-seq studies. WB:WBGene00195371 C30C11.5 No description available WB:WBGene00195372 C05E11.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00195373 F56F10.7 No description available WB:WBGene00195374 R10E8.10 Enriched in AFD; ASER; and intestine based on RNA-seq studies. Is affected by several genes including daf-16; hda-2; and hlh-26 based on RNA-seq studies. WB:WBGene00195375 C34E7.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00195376 F16F9.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195377 F45B8.6 Is affected by several genes including daf-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195378 T19E7.22 Is affected by etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195379 ZK945.10 No description available WB:WBGene00195380 C52G5.4 Is affected by met-2; spr-5; and jmjd-5 based on RNA-seq studies. WB:WBGene00195381 C53D6.17 No description available WB:WBGene00195382 F29F11.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195383 C09B8.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195384 T13H10.4 No description available WB:WBGene00195385 ZK867.5 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00195386 T09E8.6 Is affected by let-418 and dlc-1 based on RNA-seq studies. WB:WBGene00195387 F02D10.10 Is affected by lin-28; hmg-3; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195388 F12D9.3 No description available WB:WBGene00195389 F54E4.5 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00195390 ZC518.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00195391 F46H6.7 No description available WB:WBGene00195392 C07E3.13 Is affected by daf-2 based on microarray studies. WB:WBGene00195393 F28E10.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00195394 F32H2.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195395 C41A3.3 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00195396 ZK40.4 No description available WB:WBGene00195397 C54G7.5 No description available WB:WBGene00195398 F55B12.12 No description available WB:WBGene00195399 F35G2.7 Is affected by adr-1; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00195400 B0379.8 No description available WB:WBGene00195401 C06G1.7 Is affected by daf-2 based on microarray studies. WB:WBGene00195402 F44A6.7 Is affected by daf-2 based on microarray studies. WB:WBGene00195403 F28C1.10 No description available WB:WBGene00195404 C10E2.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195405 F59C6.17 Enriched in head mesodermal cell and neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00195406 B0350.67 Enriched in neurons based on RNA-seq studies. WB:WBGene00195407 F08G5.9 No description available WB:WBGene00195408 F10C1.11 Is affected by set-2 based on RNA-seq studies. WB:WBGene00195409 T10A3.2 Enriched in neurons based on RNA-seq studies. WB:WBGene00195410 C39B5.15 No description available WB:WBGene00195411 Y17G7A.2 No description available WB:WBGene00195412 K03H1.16 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00195413 D1022.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00195414 C33F10.16 Is affected by eat-2 based on microarray studies. WB:WBGene00195415 C15F1.12 No description available WB:WBGene00195416 C25F6.9 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00195417 C16C2.5 Is affected by alg-1 and lpd-3 based on RNA-seq studies. WB:WBGene00195418 F48C5.3 No description available WB:WBGene00195419 R173.5 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00195420 T10B5.12 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195421 T25F10.7 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195422 Y111B2A.31 No description available WB:WBGene00195423 F55C10.7 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00195424 Y48G8AL.17 No description available WB:WBGene00195425 ZC8.7 Is affected by cep-1; dlc-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195426 C10H11.11 Is affected by several genes including daf-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195427 F02A9.8 Is affected by cep-1; fzo-1; and etr-1 based on RNA-seq studies. WB:WBGene00195428 F55E10.8 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00195429 C45B2.9 No description available WB:WBGene00195430 C25F6.10 Is affected by several genes including cep-1; alg-1; and adr-1 based on RNA-seq studies. WB:WBGene00195431 W02F12.9 No description available WB:WBGene00195432 C56E6.10 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00195433 F41D9.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00195434 K07E8.13 No description available WB:WBGene00195435 K01A6.9 Is affected by mrps-5 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195436 Y69A2AR.37 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00195437 T07D3.10 No description available WB:WBGene00195438 K08H10.13 No description available WB:WBGene00195439 T27A8.6 Enriched in AFD based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00195440 F59B2.16 No description available WB:WBGene00195441 F07A11.9 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq and microarray studies. WB:WBGene00195442 C54D10.15 No description available WB:WBGene00195443 Y71F9B.17 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00195444 T15B7.18 No description available WB:WBGene00195445 Y23H5A.9 No description available WB:WBGene00195446 T01B4.4 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00195447 F59D12.7 No description available WB:WBGene00195448 T19B4.9 Is affected by meg-3 and meg-4 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195449 F10D7.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195450 F35G12.14 Is affected by cep-1 and klf-1 based on RNA-seq studies. WB:WBGene00195451 C09B7.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00195452 D2021.5 No description available WB:WBGene00195453 T04C12.15 Enriched in neurons based on RNA-seq studies. Is affected by daf-2; eat-2; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00195454 ZK742.8 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00195455 C48E7.12 No description available WB:WBGene00195456 T06F4.5 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00195457 K05D4.11 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00195458 K04A8.11 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00195459 F27D4.9 No description available WB:WBGene00195460 M70.6 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00195461 F28E10.7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00195462 C52B11.6 Is affected by Tunicamycin based on microarray studies. WB:WBGene00195463 ZK863.10 Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00195464 B0454.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00195465 Y37F4.10 No description available WB:WBGene00195466 C33D12.9 No description available WB:WBGene00195467 F12D9.4 No description available WB:WBGene00195468 F53H10.4 No description available WB:WBGene00195469 F46G11.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00195470 M03F8.8 No description available WB:WBGene00195471 C40C9.7 Is affected by daf-2 based on microarray studies. WB:WBGene00195472 T21B6.6 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00195473 F41E7.10 No description available WB:WBGene00195474 K03H6.8 No description available WB:WBGene00195475 K03H6.9 Is affected by daf-2 based on microarray studies. WB:WBGene00195476 F33D11.13 No description available WB:WBGene00195477 Y57G11C.1136 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195478 F58A3.6 Is affected by dlc-1 and camt-1 based on RNA-seq studies. WB:WBGene00195479 R09F10.13 Is affected by pmt-2 based on microarray studies. WB:WBGene00195480 F42D1.5 No description available WB:WBGene00195481 ZK867.6 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195482 B0350.68 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195483 F22A3.9 Is affected by pmt-2 based on microarray studies. WB:WBGene00195484 K03C7.4 Enriched in sensory neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00195485 F55A12.11 No description available WB:WBGene00195486 ZC308.5 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00195487 C24A8.7 No description available WB:WBGene00195488 F20B10.5 No description available WB:WBGene00195489 Y55D5A.8 No description available WB:WBGene00195490 C09D8.2 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00195491 H03A11.4 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195492 F36G3.6 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00195493 M03D4.74 No description available WB:WBGene00195494 F48C11.5 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00195495 K02B9.6 No description available WB:WBGene00195496 C40C9.8 No description available WB:WBGene00195497 C48C5.4 No description available WB:WBGene00195498 F56D12.8 No description available WB:WBGene00195499 H22K11.5 Enriched in AVK based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00195500 F32G8.8 No description available WB:WBGene00195501 T10B5.13 No description available WB:WBGene00195502 Y38C1AB.9 No description available WB:WBGene00195503 Y110A2AL.16 No description available WB:WBGene00195504 F11A6.4 No description available WB:WBGene00195505 R03D7.9 Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies. WB:WBGene00195506 C08C3.6 Is affected by daf-2 based on microarray studies. WB:WBGene00195507 T03G11.13 No description available WB:WBGene00195508 C11E4.9 Is affected by dlc-1 and met-2 based on RNA-seq studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00195509 C15H7.6 No description available WB:WBGene00195510 F55A8.3 No description available WB:WBGene00195511 C03C10.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00195512 C04C11.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00195513 F38B6.9 No description available WB:WBGene00195514 Y73A3A.1 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195515 ZK381.34 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195516 M01G5.7 No description available WB:WBGene00195517 C05E11.10 Is affected by several genes including prg-1; hmg-4; and hmg-3 based on RNA-seq studies. WB:WBGene00195518 ZK652.14 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195519 Y73B3A.23 Is affected by several genes including pgl-1; prg-1; and lag-1 based on RNA-seq studies. WB:WBGene00195520 C18F3.6 Is affected by adr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195521 C06A8.13 No description available WB:WBGene00195522 F01G12.9 No description available WB:WBGene00195523 C43C3.5 No description available WB:WBGene00195524 F33C8.5 Is affected by daf-2 based on microarray studies. WB:WBGene00195525 C09F9.8 Is affected by pmt-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195526 R07B1.15 No description available WB:WBGene00195527 C09D8.3 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195528 K08B5.3 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195529 F11A6.5 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00195530 T04G9.8 Is affected by cep-1 and nfki-1 based on RNA-seq studies. WB:WBGene00195531 C02B10.71 No description available WB:WBGene00195532 C03F11.5 No description available WB:WBGene00195533 Y55F3BR.12 No description available WB:WBGene00195534 C29E6.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195535 B0432.17 No description available WB:WBGene00195536 C55A6.14 Is affected by cep-1 and ifo-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195537 F10C2.9 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 and alh-4 based on RNA-seq studies. WB:WBGene00195538 M79.6 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00195539 C12D8.22 No description available WB:WBGene00195540 T10E10.8 No description available WB:WBGene00195541 F56C3.11 No description available WB:WBGene00195542 C24A3.10 Enriched in AVK and neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195543 W06H8.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195544 Y95B8A.13 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00195545 F45B8.7 No description available WB:WBGene00195546 ZK1025.11 No description available WB:WBGene00195547 T28B11.2 Enriched in AVK and neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00195548 C16E9.8 No description available WB:WBGene00195549 K02E11.13 No description available WB:WBGene00195550 C10C5.9 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00195551 C26E1.4 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195552 C05D12.8 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00195553 F15D3.10 No description available WB:WBGene00195554 T22E5.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195555 C27D11.2 No description available WB:WBGene00195556 K11G9.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00195557 Y37E11B.12 No description available WB:WBGene00195558 C18A3.13 No description available WB:WBGene00195559 K07H8.14 No description available WB:WBGene00195560 T06G6.13 No description available WB:WBGene00195561 Y38A10A.8 No description available WB:WBGene00195562 F28F5.9 No description available WB:WBGene00195563 F19H6.8 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00195564 ZC64.5 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195565 C48A7.5 Is affected by daf-2 based on microarray studies. WB:WBGene00195566 ZC64.6 No description available WB:WBGene00195567 C23F12.6 No description available WB:WBGene00195568 F12D9.5 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00195569 M117.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195570 W06F12.5 No description available WB:WBGene00195571 T24D8.10 Is affected by tdp-1 based on RNA-seq studies. WB:WBGene00195572 T21B6.7 No description available WB:WBGene00195573 K08B5.4 Is affected by daf-2 based on microarray studies. WB:WBGene00195574 ZC13.11 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195575 B0563.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00195576 Y67D8C.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195577 C06E1.12 No description available WB:WBGene00195578 W10C8.7 No description available WB:WBGene00195579 C47G2.10 No description available WB:WBGene00195580 R07D5.3 No description available WB:WBGene00195581 F26C11.5 No description available WB:WBGene00195582 C06E8.6 Is affected by cep-1; daf-2; and pmt-2 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195583 R11B5.2 Is affected by eat-2 based on microarray studies. WB:WBGene00195584 C34F6.13 No description available WB:WBGene00195585 T28D6.11 No description available WB:WBGene00195586 C34F11.10 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195587 R04F11.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00195588 K08E5.7 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by mrps-5; camt-1; and etr-1 based on RNA-seq studies. WB:WBGene00195589 Y116F11B.19 No description available WB:WBGene00195590 F43G9.14 No description available WB:WBGene00195591 R53.9 No description available WB:WBGene00195592 T02E1.10 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00195593 C34E11.8 No description available WB:WBGene00195594 F31E8.7 Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00195595 C56E6.11 No description available WB:WBGene00195596 C15C6.5 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00195597 Y73F8A.1161 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195598 T21D9.3 Enriched in neurons based on RNA-seq studies. WB:WBGene00195599 K08E5.8 No description available WB:WBGene00195600 K08H10.14 Is affected by dlc-1; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00195601 M176.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00195602 T14B4.11 Is affected by pmt-2 based on microarray studies. WB:WBGene00195603 T04F8.10 No description available WB:WBGene00195604 T14B4.12 No description available WB:WBGene00195605 Y53C10A.16 No description available WB:WBGene00195606 T26E3.13 No description available WB:WBGene00195607 Y73F8A.1162 No description available WB:WBGene00195608 F56G4.8 No description available WB:WBGene00195609 Y41C4A.23 No description available WB:WBGene00195610 ZC123.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00195611 K08D9.7 No description available WB:WBGene00195612 Y51H7C.16 No description available WB:WBGene00195613 T06D10.5 Enriched in neurons based on RNA-seq studies. Is affected by ikb-1 and etr-1 based on RNA-seq studies. WB:WBGene00195614 F48C5.4 Is affected by eat-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195615 Y106G6A.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195616 C49F8.5 Is affected by adr-1 and etr-1 based on RNA-seq studies. WB:WBGene00195617 C52B9.13 No description available WB:WBGene00195618 F37D6.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00195619 C17C3.21 Is affected by several genes including pgl-1; glh-1; and met-2 based on RNA-seq studies. WB:WBGene00195620 F59C12.6 No description available WB:WBGene00195621 F43H9.5 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and set-2 based on RNA-seq studies. WB:WBGene00195622 C50D2.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195623 Y54G2A.58 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195624 R31.4 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195625 Y58A7A.7 Is affected by tdp-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00195626 F13B12.12 No description available WB:WBGene00195627 R13A1.13 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00195628 C48D1.10 Enriched in neurons based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00195629 C05G5.8 Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195630 F26D11.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00195631 F46F2.9 Is affected by chd-3; let-418; and dlc-1 based on RNA-seq studies. WB:WBGene00195632 Y80E2A.1 Enriched in head mesodermal cell and neurons based on RNA-seq studies. Is affected by adr-1 and camt-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195633 F44C4.9 No description available WB:WBGene00195634 AC3.14 No description available WB:WBGene00195635 T27D12.7 No description available WB:WBGene00195636 ZK813.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00195637 C10F3.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00195638 W03G11.6 Is affected by pgrn-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00195639 T03F7.10 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195640 Y59A8B.27 No description available WB:WBGene00195641 F58F12.5 Is affected by Tunicamycin based on microarray studies. WB:WBGene00195642 R08B4.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195643 C01F1.7 No description available WB:WBGene00195644 Y57A10B.8 Is affected by etr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195645 F25F8.5 Enriched in neurons based on RNA-seq studies. Is affected by alh-4 based on RNA-seq studies. WB:WBGene00195646 T01C1.5 No description available WB:WBGene00195647 ZC487.6 Is affected by pmt-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195648 W09B12.2 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195649 F10E9.13 No description available WB:WBGene00195650 F58F12.6 No description available WB:WBGene00195651 F07C3.11 Is affected by chd-3 and let-418 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00195652 K11H3.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00195653 W10D9.7 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00195654 Y73B6BL.271 No description available WB:WBGene00195655 F43D9.7 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00195656 T01H3.6 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00195657 D1009.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00195658 C34D1.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00195659 Y69E1A.9 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00195660 R07E3.9 No description available WB:WBGene00195661 C08G9.4 No description available WB:WBGene00195662 T19F4.2 Is affected by adr-1 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00195663 T24D11.2 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00195664 C09B8.11 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00195665 C48A7.6 No description available WB:WBGene00195666 C34E11.9 Enriched in neurons based on RNA-seq studies. Is affected by alg-1; mrps-5; and camt-1 based on RNA-seq studies. WB:WBGene00195667 F46C8.9 Is affected by chd-3 and let-418 based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00195668 R11B5.3 Is affected by etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195669 F47E1.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195670 F52B10.4 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00195671 R186.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195672 Y37E3.26 No description available WB:WBGene00195673 K08A8.5 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00195674 B0280.19 No description available WB:WBGene00195675 F49C5.13 Is affected by dpy-21 and pmt-2 based on RNA-seq and microarray studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00195676 Y49E10.31 No description available WB:WBGene00195677 F31E8.8 No description available WB:WBGene00195678 W03G11.7 Is affected by pgrn-1 and dpy-21 based on RNA-seq studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00195679 Y51H7C.17 No description available WB:WBGene00195680 T22B11.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00195681 C14E2.9 No description available WB:WBGene00195682 F57G4.12 No description available WB:WBGene00195683 C15C6.6 No description available WB:WBGene00195684 F08F3.12 Is affected by hpl-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00195685 Y42A5A.8 No description available WB:WBGene00195686 Y70D2A.3 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195687 K03A1.8 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195688 ZK180.9 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195689 K10D6.7 No description available WB:WBGene00195690 ZK381.35 Is affected by cep-1; daf-2; and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00195691 C35D10.18 No description available WB:WBGene00195692 C14F11.8 Is affected by dlc-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195693 T26H10.3 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195694 C43G2.25 No description available WB:WBGene00195695 F54D12.12 No description available WB:WBGene00195696 C54G7.6 No description available WB:WBGene00195697 F28C1.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00195698 T22E5.9 No description available WB:WBGene00195699 K04G11.7 No description available WB:WBGene00195700 F13D12.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00195701 F09B9.6 Enriched in AVK based on RNA-seq studies. WB:WBGene00195702 F49C5.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00195703 F26A10.5 No description available WB:WBGene00195704 C13C12.4 Enriched in neurons based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00195705 Y37A1B.330 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00195706 K07C10.4 No description available WB:WBGene00195707 C11G10.3 Enriched in neurons based on RNA-seq studies. WB:WBGene00195708 F37B12.6 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195709 K04D7.8 Is affected by cep-1 and rnp-6 based on RNA-seq studies. WB:WBGene00195710 B0416.8 Is affected by daf-2 based on microarray studies. WB:WBGene00195711 F56E3.6 No description available WB:WBGene00195712 F41D9.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195713 F45D3.7 No description available WB:WBGene00195714 C10F3.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00195715 F10F2.10 No description available WB:WBGene00195716 R09A1.6 No description available WB:WBGene00195717 T04C10.6 No description available WB:WBGene00195718 W06B11.5 No description available WB:WBGene00195719 C36F7.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00195720 F09E5.18 No description available WB:WBGene00195721 ZC506.5 No description available WB:WBGene00195722 C31H2.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00195723 C35A5.12 No description available WB:WBGene00195724 C04C3.10 No description available WB:WBGene00195725 F48B9.9 Is affected by ifo-1 based on microarray studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00195726 Y116F11B.20 No description available WB:WBGene00195727 ZK377.4 Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies. WB:WBGene00195728 T28D9.13 Is affected by pmt-2; ints-4; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00195729 Y7A5A.14 Is affected by daf-2 based on RNA-seq studies. WB:WBGene00195730 F54C9.15 No description available WB:WBGene00195731 C49F8.6 No description available WB:WBGene00195732 F14H12.9 Is affected by several genes including eat-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00195733 T28B11.3 Is affected by cep-1; dlc-1; and mrps-5 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195734 F09C12.11 No description available WB:WBGene00195735 ZK185.6 No description available WB:WBGene00195736 F35E8.17 No description available WB:WBGene00195737 Y82E9BR.27 Is affected by cep-1 and nhr-86 based on RNA-seq studies. WB:WBGene00195738 T27F2.5 No description available WB:WBGene00195739 Y66A7AL.1 Is affected by cep-1 and daf-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00195740 F54E4.6 Is affected by dpy-21 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195741 W05B2.10 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195742 F54A3.7 No description available WB:WBGene00195743 F55D10.6 No description available WB:WBGene00195744 C14B9.11 Is affected by several genes including skn-1; cep-1; and unc-70 based on RNA-seq studies. Is affected by Tunicamycin based on RNA-seq studies. WB:WBGene00195745 ZK836.4 Is affected by cep-1; dlc-1; and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00195746 F25B5.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195747 F17C8.10 No description available WB:WBGene00195748 T28B11.4 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00195749 K02F2.7 No description available WB:WBGene00195750 F18E2.7 No description available WB:WBGene00195751 C12C8.5 Is affected by daf-2 based on microarray studies. WB:WBGene00195752 Y106G6A.7 Is affected by cep-1; dlc-1; and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00195753 B0350.69 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00195754 W09H1.7 Is affected by cep-1; adr-1; and dlc-1 based on RNA-seq studies. WB:WBGene00195755 B0207.13 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00195756 H05G16.2 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00195757 T06A10.105 Enriched in neurons based on RNA-seq studies. Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00195758 F18E2.8 No description available WB:WBGene00195759 T02E9.10 No description available WB:WBGene00195760 K01A6.10 Is affected by daf-2 based on microarray studies. WB:WBGene00195761 C18B12.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195762 ZC64.7 No description available WB:WBGene00195763 F40H6.7 No description available WB:WBGene00195764 C04C11.6 No description available WB:WBGene00195765 T08G2.4 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195766 F10C1.12 Is affected by set-2 based on RNA-seq studies. WB:WBGene00195767 T08A9.15 No description available WB:WBGene00195768 T28B4.5 No description available WB:WBGene00195769 Y39B6A.70 No description available WB:WBGene00195770 H21P03.4 Is affected by daf-2 based on microarray studies. WB:WBGene00195771 W05F2.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195772 C03H12.2 Is affected by sodium arsenite based on RNA-seq studies. WB:WBGene00195773 Y66D12A.26 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195774 F20D1.12 No description available WB:WBGene00195775 T05A6.8 Is affected by let-418 based on RNA-seq studies. WB:WBGene00195776 F37D6.8 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195777 D2023.10 Enriched in AVK based on RNA-seq studies. WB:WBGene00195778 PAR2.5 No description available WB:WBGene00195779 Y71H2AM.27 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00195780 T03G11.14 No description available WB:WBGene00195781 T01B10.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195782 T13H2.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195783 D2007.6 No description available WB:WBGene00195784 F31E8.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195785 C18B12.10 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by pmt-2; bcat-1; and etr-1 based on microarray and RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195786 C34H3.4 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00195787 F40E10.7 No description available WB:WBGene00195788 F25D1.9 No description available WB:WBGene00195789 K08A8.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00195790 F58H1.10 Enriched in sensory neurons based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00195791 F42H10.9 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00195792 F58A4.16 Is affected by cep-1; hpl-2; and nhr-86 based on RNA-seq studies. WB:WBGene00195793 B0496.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195794 B0393.11 Is affected by tdp-1 and hmg-3 based on RNA-seq studies. WB:WBGene00195795 R07E4.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00195796 Y92C3A.4 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00195797 T14F9.6 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00195798 C33A11.5 Is affected by xpf-1 based on RNA-seq studies. WB:WBGene00195799 K07E12.3 No description available WB:WBGene00195800 T19D12.11 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00195801 F35B12.11 Is affected by cep-1; fog-2; and fzo-1 based on RNA-seq studies. WB:WBGene00195802 H14N18.5 No description available WB:WBGene00195803 F46E10.13 Is affected by several genes including cep-1; adr-1; and tdp-1 based on RNA-seq studies. WB:WBGene00195804 F11E6.19 Is affected by daf-2 based on microarray studies. WB:WBGene00195805 F35G2.8 Is affected by cep-1 based on RNA-seq studies. Is affected by 4-bromodiphenyl ether and Oligosaccharides based on microarray studies. WB:WBGene00195806 EGAP3.1 No description available WB:WBGene00195807 F56H11.8 No description available WB:WBGene00195808 F55C12.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195809 ZC455.14 Is affected by etr-1 based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00195810 Y97E10AM.2 No description available WB:WBGene00195811 H09I01.4 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195812 C25B8.9 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00195813 F31C3.13 Is affected by tdp-1 and cox-5B based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00195814 F59D12.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00195815 H08J11.3 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195816 C34B4.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00195817 K10C3.7 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00195818 F48C5.5 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195819 C13G3.4 Is affected by fog-2 and etr-1 based on RNA-seq studies. WB:WBGene00195820 T22E5.10 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195821 T03G6.4 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00195822 F28F9.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00195823 F53A9.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195824 F27D9.9 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00195825 F27E11.6 Is affected by adr-1 and met-2 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195826 B0496.13 Is affected by cep-1 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00195827 Y34B4A.12 No description available WB:WBGene00195828 Y105C5B.1414 Enriched in neurons based on RNA-seq studies. WB:WBGene00195829 T26H2.13 No description available WB:WBGene00195830 H03A11.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00195831 K03B8.15 No description available WB:WBGene00195832 T28B11.5 Is affected by several genes including daf-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195833 mir-8209 No description available WB:WBGene00195834 H13N06.8 No description available WB:WBGene00195835 C34B2.12 Is affected by daf-2 based on microarray studies. WB:WBGene00195836 F13E6.8 Is affected by met-2 based on RNA-seq studies. WB:WBGene00195837 F49E10.9 No description available WB:WBGene00195838 F52B10.5 No description available WB:WBGene00195839 T23F1.8 No description available WB:WBGene00195840 F35B12.12 Enriched in neurons based on RNA-seq studies. Is affected by bcat-1 and etr-1 based on RNA-seq studies. WB:WBGene00195841 C18A3.14 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195842 F56E3.7 No description available WB:WBGene00195843 F57G12.3 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195844 T04F3.6 No description available WB:WBGene00195845 F15A2.8 Is affected by cep-1 and camt-1 based on RNA-seq studies. WB:WBGene00195846 F02H6.72 No description available WB:WBGene00195847 Y52E8A.7 No description available WB:WBGene00195848 F54H5.7 Is affected by ifo-1 based on microarray studies. WB:WBGene00195849 ZC250.6 Is affected by emr-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195850 F57C7.7 No description available WB:WBGene00195851 F09C8.3 No description available WB:WBGene00195852 T13H10.5 No description available WB:WBGene00195853 Y73B6BL.272 No description available WB:WBGene00195854 F32D8.16 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195855 W06A7.6 Is affected by cep-1; spt-16; and adr-1 based on RNA-seq studies. WB:WBGene00195856 C55A6.15 No description available WB:WBGene00195857 C16E9.9 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00195858 F48C11.6 No description available WB:WBGene00195859 W09D12.5 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195860 ZK897.8 No description available WB:WBGene00195861 C48B6.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195862 T01B7.10 Is affected by dpy-21 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195863 F35H10.14 Is affected by emr-1 and ins-11 based on RNA-seq studies. Is affected by Tunicamycin and silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195864 F41A4.3 Is affected by prg-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195865 2RSSE.4 No description available WB:WBGene00195866 F14F3.7 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00195867 W06G6.18 Is affected by daf-2 based on microarray studies. WB:WBGene00195868 F26A10.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195869 D2023.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00195870 F22E10.7 No description available WB:WBGene00195871 K04B12.5 No description available WB:WBGene00195872 cTel17.1 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00195873 H11E01.4 No description available WB:WBGene00195874 R04F11.8 No description available WB:WBGene00195875 F11C7.8 No description available WB:WBGene00195876 H03E18.3 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195877 R07E4.8 Is affected by cep-1; hpl-2; and etr-1 based on RNA-seq studies. WB:WBGene00195878 F46F3.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195879 F49E10.10 Is affected by daf-2 based on microarray studies. WB:WBGene00195880 F23H12.12 No description available WB:WBGene00195881 T28B11.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195882 F59B10.7 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sek-1; pgl-1; and cep-1 based on RNA-seq studies. WB:WBGene00195883 K02B12.10 Is affected by daf-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195884 C17E4.14 No description available WB:WBGene00195885 F38B7.12 No description available WB:WBGene00195886 F08C6.8 Is affected by daf-2 based on microarray studies. WB:WBGene00195887 Y47D3A.33 No description available WB:WBGene00195888 K07A12.9 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00195889 T01B6.5 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00195890 F13D11.7 Is affected by cep-1; daf-2; and alh-4 based on RNA-seq and microarray studies. WB:WBGene00195891 C09H10.11 No description available WB:WBGene00195892 F35D2.7 No description available WB:WBGene00195893 F43D2.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195894 ZK262.16 No description available WB:WBGene00195895 T14G11.4 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195896 F31E3.8 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; lem-2; and spc-1 based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00195897 Y41G9A.13 No description available WB:WBGene00195898 W01H2.4 Is affected by elli-1 and daf-2 based on microarray studies. WB:WBGene00195899 F11D5.11 No description available WB:WBGene00195900 K04D7.9 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00195901 H06I04.10 No description available WB:WBGene00195902 T21B4.18 No description available WB:WBGene00195903 K02E2.14 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00195904 T24F1.8 No description available WB:WBGene00195905 ZK381.36 Is affected by alg-1 based on RNA-seq studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00195906 C13G5.3 No description available WB:WBGene00195907 T14F9.7 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00195908 Y46E12BL.5 No description available WB:WBGene00195909 Y106G6A.8 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on microarray and RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195910 F29F11.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195911 C01B10.45 Is affected by daf-2 and ifo-1 based on microarray studies. WB:WBGene00195912 H22K11.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195913 F54F12.4 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00195914 F14H12.10 Is affected by several genes including daf-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195915 C07H6.11 No description available WB:WBGene00195916 Y71A12B.26 Is affected by rnp-6 based on RNA-seq studies. WB:WBGene00195917 K09B11.19 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00195918 C35A11.5 No description available WB:WBGene00195919 T24B8.9 No description available WB:WBGene00195920 C54D10.16 Is affected by pmt-2 based on microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00195921 F12F6.13 No description available WB:WBGene00195922 C24H11.10 No description available WB:WBGene00195923 Y54E10A.19 No description available WB:WBGene00195924 Y47H9A.3 No description available WB:WBGene00195925 W01C8.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195926 T09B4.13 Is affected by cep-1 and set-2 based on RNA-seq studies. WB:WBGene00195927 F54D1.17 Is affected by rnp-6 based on RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00195928 F46G11.9 No description available WB:WBGene00195929 Y51H7BR.9 Is affected by daf-2 based on microarray studies. WB:WBGene00195930 F42A10.11 No description available WB:WBGene00195931 Y57A10A.38 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195932 F33D4.11 No description available WB:WBGene00195933 C43D7.13 No description available WB:WBGene00195934 T09D3.10 No description available WB:WBGene00195935 F42G8.16 Is affected by unc-70 and plp-1 based on RNA-seq studies. WB:WBGene00195936 C02D5.5 No description available WB:WBGene00195937 C33G3.8 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00195938 R09A8.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195939 K11G12.8 Is affected by daf-2 based on microarray studies. WB:WBGene00195940 ZK470.7 No description available WB:WBGene00195941 F55B12.13 No description available WB:WBGene00195942 C15C8.9 Is affected by cep-1 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00195943 W08F4.14 No description available WB:WBGene00195944 F22A3.10 No description available WB:WBGene00195945 R03D7.10 No description available WB:WBGene00195946 BE0003N10.4 No description available WB:WBGene00195947 C02F4.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and mrps-5 based on RNA-seq studies. WB:WBGene00195948 Y7A9D.62 No description available WB:WBGene00195949 Y53F4B.52 No description available WB:WBGene00195950 F08C6.9 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195951 C23F12.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195952 K04H4.9 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195953 C42D8.10 No description available WB:WBGene00195954 F44A6.8 No description available WB:WBGene00195955 Y71A12C.4 No description available WB:WBGene00195956 C54E4.6 No description available WB:WBGene00195957 C14F11.9 No description available WB:WBGene00195958 ZK867.7 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00195959 H03A11.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00195960 ZK381.37 No description available WB:WBGene00195961 T28B4.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00195962 ZK973.13 Is affected by sams-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00195963 Y44A6B.5 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00195964 F56A11.8 No description available WB:WBGene00195965 F26A10.7 No description available WB:WBGene00195966 C16E9.10 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00195967 K08C7.9 No description available WB:WBGene00195968 R11G1.8 No description available WB:WBGene00195969 ZK563.8 No description available WB:WBGene00195970 F52B10.6 Is affected by cep-1; chd-3; and let-418 based on RNA-seq studies. WB:WBGene00195971 F55C5.12 Is affected by dlc-1 and ikb-1 based on RNA-seq studies. WB:WBGene00195972 C38C6.9 No description available WB:WBGene00195973 B0495.12 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00195974 C33B4.7 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00195975 K09A9.9 No description available WB:WBGene00195976 W07G1.11 No description available WB:WBGene00195977 C56E6.12 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00195978 VB0395L.2 No description available WB:WBGene00195979 F31F7.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00195980 Y53F4B.53 Is affected by tatn-1 based on RNA-seq studies. WB:WBGene00195981 W01C8.10 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00195982 ZK836.5 Is affected by cep-1 and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00195983 K08B12.6 Is affected by cep-1; ifo-1; and lag-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00195984 C07H4.3 No description available WB:WBGene00195985 Y6B3B.12 No description available WB:WBGene00195986 F39C12.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00195987 C04C11.7 No description available WB:WBGene00195988 Y54G2A.59 Enriched in neurons based on RNA-seq studies. WB:WBGene00195989 K02A11.5 No description available WB:WBGene00195990 Y69A2AR.38 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00195991 F02E11.8 No description available WB:WBGene00195992 F09F9.7 Is affected by met-2 based on RNA-seq studies. WB:WBGene00195993 C24G6.10 Is affected by Tunicamycin based on microarray studies. WB:WBGene00195994 F39B3.4 No description available WB:WBGene00195995 C42D8.11 No description available WB:WBGene00195996 Y54G9A.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00195997 F42H10.10 No description available WB:WBGene00195998 Y53H1C.5 No description available WB:WBGene00195999 Y105E8A.37 Enriched in neurons based on RNA-seq studies. WB:WBGene00196000 Y50D7A.14 No description available WB:WBGene00196001 F52B10.7 No description available WB:WBGene00196002 K03C7.5 Enriched in sensory neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00196003 F22D3.7 No description available WB:WBGene00196004 F13D11.8 Is affected by daf-2 based on microarray studies. WB:WBGene00196005 ZK867.8 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196006 C01F4.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00196007 B0334.16 No description available WB:WBGene00196008 C25D7.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196009 F19C6.9 No description available WB:WBGene00196010 C04H4.2 Is affected by Tunicamycin based on microarray studies. WB:WBGene00196011 T06A4.4 No description available WB:WBGene00196012 F32A6.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00196013 R08E3.5 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196014 F47B7.10 Is affected by ifo-1 and mrps-5 based on microarray and RNA-seq studies. WB:WBGene00196015 Y67D8A.6 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196016 W03A3.4 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00196017 C17D12.10 Is affected by daf-2 based on microarray studies. WB:WBGene00196018 F28F8.11 No description available WB:WBGene00196019 F12D9.6 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00196020 F35G2.9 Is affected by daf-2 based on microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00196021 F09G2.10 Enriched in head mesodermal cell; neurons; and sensory neurons based on RNA-seq studies. Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00196022 B0495.13 Enriched in neurons based on RNA-seq studies. Is affected by bcat-1 based on RNA-seq studies. WB:WBGene00196023 T03G11.15 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196024 C32C4.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196025 C52E4.13 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00196026 Y39A1B.5 No description available WB:WBGene00196027 C30B5.10 Is affected by sodium arsenite based on RNA-seq studies. WB:WBGene00196028 C32D5.15 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00196029 T06F4.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00196030 Y39B6A.71 No description available WB:WBGene00196031 Y79H2A.13 No description available WB:WBGene00196032 T18D3.10 Is affected by lbp-3 based on RNA-seq studies. WB:WBGene00196033 Y17D7C.7 No description available WB:WBGene00196034 T04C12.16 No description available WB:WBGene00196035 T27A1.8 Is affected by daf-2 based on microarray studies. WB:WBGene00196036 F49H12.8 No description available WB:WBGene00196037 Y17D7B.11 No description available WB:WBGene00196038 Y51H7C.18 No description available WB:WBGene00196039 C04E7.7 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00196040 Y75B8A.45 No description available WB:WBGene00196041 R02D5.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00196042 K11C4.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196043 ZK973.14 Is affected by sams-3 based on RNA-seq studies. WB:WBGene00196044 ZK381.38 Enriched in neurons based on RNA-seq studies. WB:WBGene00196045 F58F12.7 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196046 F33G12.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196047 C02C6.4 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196048 T11F1.10 No description available WB:WBGene00196049 ZK381.39 No description available WB:WBGene00196050 C41G11.6 No description available WB:WBGene00196051 Y22F5A.8 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196052 T27E4.14 No description available WB:WBGene00196053 F11H8.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196054 F53B3.8 No description available WB:WBGene00196055 T07D1.8 No description available WB:WBGene00196056 T19C4.16 No description available WB:WBGene00196057 ZK84.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196058 Y55F3BR.13 No description available WB:WBGene00196059 D2023.12 Is affected by several genes including lag-1; set-2; and unc-70 based on RNA-seq studies. WB:WBGene00196060 VB0365.1 Enriched in AVK based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00196061 F07B10.8 No description available WB:WBGene00196062 C49A1.11 No description available WB:WBGene00196063 F25G6.12 Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq studies. WB:WBGene00196064 ZC477.15 No description available WB:WBGene00196065 C34F6.14 Is affected by daf-2 based on microarray studies. WB:WBGene00196066 T19C4.17 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00196067 Y39G8C.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196068 F40F9.13 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196069 Y39A3CL.8 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00196070 C16A3.14 No description available WB:WBGene00196071 F56F3.8 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00196072 Y39A3B.6 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196073 F54D12.13 No description available WB:WBGene00196074 K12H6.13 No description available WB:WBGene00196075 Y105E8A.38 Is affected by Tunicamycin; Cry5B; and Oligosaccharides based on microarray studies. WB:WBGene00196076 Y71F9AR.5 No description available WB:WBGene00196077 C06A1.10 No description available WB:WBGene00196078 T02E9.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00196079 C29E6.9 No description available WB:WBGene00196080 Y54G9A.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00196081 K06C4.18 No description available WB:WBGene00196082 F54C4.5 No description available WB:WBGene00196083 C53B7.9 No description available WB:WBGene00196084 B0454.14 No description available WB:WBGene00196085 R173.6 No description available WB:WBGene00196086 F16H9.4 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196087 F08G5.10 No description available WB:WBGene00196088 F58H1.11 Is affected by dlc-1 based on RNA-seq studies. Is affected by Tunicamycin and Oligosaccharides based on microarray studies. WB:WBGene00196089 C15F1.13 Is affected by pmt-2 based on microarray studies. WB:WBGene00196090 F02G3.2 No description available WB:WBGene00196091 C50F4.18 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00196092 ZK632.15 No description available WB:WBGene00196093 K03H9.6 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00196094 H19M22.5 Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00196095 F22B3.12 No description available WB:WBGene00196096 ZK616.62 Is affected by emr-1; cep-1; and adr-1 based on RNA-seq studies. WB:WBGene00196097 Y105E8B.12 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196098 Y55F3AR.4 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196099 T09B4.14 Is affected by meg-3; meg-4; and pptr-1 based on RNA-seq studies. WB:WBGene00196100 K10C3.8 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 and ints-4 based on RNA-seq studies. WB:WBGene00196101 T20F10.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196102 C29H12.7 No description available WB:WBGene00196103 Y51A2D.24 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00196104 C48D1.11 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196105 C18D1.11 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00196106 ZC504.7 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00196107 F41C6.8 No description available WB:WBGene00196108 H02I12.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00196109 K02H8.2 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196110 T01C2.3 No description available WB:WBGene00196111 C33B4.8 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196112 K10D6.8 Enriched in neurons based on RNA-seq studies. Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00196113 F13H6.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00196114 Y51H7C.19 No description available WB:WBGene00196115 F45B8.8 No description available WB:WBGene00196116 T10E9.11 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00196117 F49E10.11 No description available WB:WBGene00196118 Y32F6B.5 No description available WB:WBGene00196119 F44E5.6 No description available WB:WBGene00196120 T06H11.7 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00196121 C40H5.10 No description available WB:WBGene00196122 C24B5.7 No description available WB:WBGene00196123 F55C5.13 Is affected by endu-2 and lpd-3 based on microarray and RNA-seq studies. Is affected by procyanidin and Oligosaccharides based on microarray studies. WB:WBGene00196124 F57B10.16 Enriched in sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196125 R01E6.9 No description available WB:WBGene00196126 T07H8.10 No description available WB:WBGene00196127 K02E11.14 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00196128 Y51A2D.25 Is affected by hmg-3 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00196129 F11A6.6 Is affected by ifo-1 based on microarray studies. WB:WBGene00196130 C54D1.8 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196131 C56G2.16 No description available WB:WBGene00196132 C34H3.5 No description available WB:WBGene00196133 C43D7.14 No description available WB:WBGene00196134 C53B4.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196135 Y50D7A.15 No description available WB:WBGene00196136 C16C8.23 No description available WB:WBGene00196137 T18H9.8 No description available WB:WBGene00196138 C05B10.14 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 and lpd-3 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196139 T01C1.6 No description available WB:WBGene00196140 T07F12.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00196141 R10E12.4 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00196142 B0403.7 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00196143 K07A1.18 No description available WB:WBGene00196144 Y40H4A.3 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196145 T14F9.8 No description available WB:WBGene00196146 F10G8.10 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; mrps-5; and hlh-26 based on RNA-seq studies. WB:WBGene00196147 W02A2.10 No description available WB:WBGene00196148 B0457.8 No description available WB:WBGene00196149 T28C12.7 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00196150 C30A5.11 Is affected by daf-12 based on RNA-seq studies. WB:WBGene00196151 Y48G9A.17 No description available WB:WBGene00196152 F54E4.7 No description available WB:WBGene00196153 T14G12.8 No description available WB:WBGene00196154 F28F9.8 Is affected by spr-5 based on RNA-seq studies. WB:WBGene00196155 F40B5.4 No description available WB:WBGene00196156 T19D7.8 No description available WB:WBGene00196157 C07A4.4 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196158 C52E12.8 No description available WB:WBGene00196159 K04B12.6 No description available WB:WBGene00196160 T14G8.5 No description available WB:WBGene00196161 T13H10.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00196162 C05E11.11 Is affected by dlc-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196163 F23H12.13 Is affected by hmg-4; set-2; and nfki-1 based on RNA-seq studies. WB:WBGene00196164 C29E6.10 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196165 C53D6.18 Is affected by cep-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00196166 F45E4.16 Is affected by cep-1; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00196167 W06A7.7 No description available WB:WBGene00196168 F39D8.5 No description available WB:WBGene00196169 Y46E12A.6 Is affected by daf-2 based on microarray studies. WB:WBGene00196170 C04C11.8 Is affected by daf-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196171 F12D9.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00196172 Y50D4B.8 Is affected by daf-2 and wdr-23 based on microarray and RNA-seq studies. WB:WBGene00196173 C07E3.14 No description available WB:WBGene00196174 F28F5.10 Is affected by ifo-1 based on microarray studies. WB:WBGene00196175 W03G11.8 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; alg-1; and glh-1 based on RNA-seq studies. WB:WBGene00196176 T28B11.7 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 and lpd-3 based on RNA-seq studies. Is affected by Cry5B; silicon dioxide nanoparticle; and Oligosaccharides based on microarray studies. WB:WBGene00196177 F54C4.6 No description available WB:WBGene00196178 D1022.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00196179 Y51H7C.20 No description available WB:WBGene00196180 T19D2.6 No description available WB:WBGene00196181 C26F1.13 No description available WB:WBGene00196182 F26G1.12 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00196183 T06F4.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00196184 C10E2.8 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 and met-2 based on microarray and RNA-seq studies. WB:WBGene00196185 F28F9.9 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00196186 T09A5.16 Is affected by cep-1 and jmjd-5 based on RNA-seq studies. WB:WBGene00196187 Y53H1C.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00196188 F15C11.4 Enriched in sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196189 ZK40.5 No description available WB:WBGene00196190 F12D9.8 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00196191 C18C4.12 No description available WB:WBGene00196192 R01B10.7 No description available WB:WBGene00196193 K01B6.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196194 C05C9.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196195 F28E10.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196196 T21E12.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00196197 F09F3.14 Enriched in AFD; ASER; and PLM based on RNA-seq studies. WB:WBGene00196198 C16E9.11 No description available WB:WBGene00196199 T18D3.11 No description available WB:WBGene00196200 Y58A7A.8 Is affected by several genes including daf-2; lem-2; and emr-1 based on RNA-seq and microarray studies. WB:WBGene00196201 T19C4.18 No description available WB:WBGene00196202 W04D2.8 Is affected by chd-3; let-418; and eat-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00196203 K03H1.17 No description available WB:WBGene00196204 B0379.9 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196205 Y111B2A.32 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00196206 F28D1.19 No description available WB:WBGene00196207 F41D9.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196208 C39D10.13 No description available WB:WBGene00196209 C41A3.4 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00196210 F02D10.11 Is affected by daf-2 based on microarray studies. WB:WBGene00196211 F37D6.9 No description available WB:WBGene00196212 F07B7.15 Is affected by daf-2 based on microarray studies. Is affected by Tunicamycin and Cry5B based on microarray studies. WB:WBGene00196213 K12G11.7 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00196214 C56E6.13 No description available WB:WBGene00196215 D2092.12 No description available WB:WBGene00196216 C05A9.3 Is affected by cep-1; camt-1; and etr-1 based on RNA-seq studies. WB:WBGene00196217 C48D1.12 No description available WB:WBGene00196218 M70.7 Is affected by daf-2 based on microarray studies. WB:WBGene00196219 C10H11.12 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00196220 C24H12.13 No description available WB:WBGene00196221 B0350.70 Enriched in neurons based on RNA-seq studies. WB:WBGene00196222 H19M22.6 Is affected by eat-2 based on microarray studies. WB:WBGene00196223 ZK470.8 No description available WB:WBGene00196224 Y54E10A.20 No description available WB:WBGene00196225 T21H3.6 Is affected by pmt-2 based on microarray studies. WB:WBGene00196226 K01A6.11 No description available WB:WBGene00196227 C25F6.11 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00196228 F26A10.8 Is affected by cep-1; daf-2; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00196229 C14E2.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196230 Y73B6BL.273 No description available WB:WBGene00196231 F57B7.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00196232 K07E8.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00196233 C54D2.8 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00196234 T10B11.9 Enriched in GABAergic neurons based on microarray studies. WB:WBGene00196235 W10C8.8 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00196236 M03F4.9 No description available WB:WBGene00196237 F55C10.8 No description available WB:WBGene00196238 C40C9.9 No description available WB:WBGene00196239 F55E10.9 No description available WB:WBGene00196240 C25F6.12 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196241 ZK1193.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196242 K07C6.16 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00196243 F26A3.11 No description available WB:WBGene00196244 B0524.8 No description available WB:WBGene00196245 R08C7.16 Is affected by zip-3 based on RNA-seq studies. WB:WBGene00196246 C05D9.10 No description available WB:WBGene00196247 R07D5.4 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196248 R09F10.14 No description available WB:WBGene00196249 C54D10.17 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00196250 ZC13.12 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196251 C27A7.10 Enriched in neurons based on RNA-seq studies. Is affected by alh-4 based on RNA-seq studies. WB:WBGene00196252 T19E7.23 No description available WB:WBGene00196253 T21B6.8 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00196254 F11D5.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196255 C43F9.14 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 and camt-1 based on RNA-seq studies. WB:WBGene00196256 B0454.15 No description available WB:WBGene00196257 T04C12.17 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196258 F25G6.13 Is affected by cep-1 and alh-4 based on RNA-seq studies. WB:WBGene00196259 F28E10.9 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00196260 F32B5.10 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196261 E02A10.6 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196262 T01B4.5 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196263 R08E3.6 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00196264 F09A5.10 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00196265 C08C3.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196266 C47G2.11 No description available WB:WBGene00196267 H32C10.95 Enriched in neurons based on RNA-seq studies. WB:WBGene00196268 F52E10.7 Is affected by daf-2 based on microarray studies. WB:WBGene00196269 Y57A10A.39 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196270 F48E3.11 No description available WB:WBGene00196271 F08C6.10 No description available WB:WBGene00196272 C31G12.6 No description available WB:WBGene00196273 H13N06.9 No description available WB:WBGene00196274 C09D8.4 Enriched in NSM based on RNA-seq studies. WB:WBGene00196275 K08A8.7 Is affected by cep-1 and mett-10 based on RNA-seq studies. WB:WBGene00196276 C30F8.5 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00196277 T19D2.7 No description available WB:WBGene00196278 Y50D4C.7 No description available WB:WBGene00196279 Y67A10A.343 Is affected by daf-2 based on microarray studies. WB:WBGene00196280 M01H9.7 Is affected by cox-5B; kri-1; and mpk-2 based on RNA-seq studies. WB:WBGene00196281 C16E9.12 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00196282 F46G11.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00196283 B0391.13 No description available WB:WBGene00196284 F26A10.9 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00196285 F40H3.7 Enriched in NSM based on RNA-seq studies. Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196286 F11D5.13 No description available WB:WBGene00196287 C05D2.13 Is affected by daf-2 based on microarray studies. WB:WBGene00196288 R153.3 No description available WB:WBGene00196289 T14E8.5 No description available WB:WBGene00196290 ZK593.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196291 C15H7.7 No description available WB:WBGene00196292 F21D9.9 No description available WB:WBGene00196293 F35G2.10 No description available WB:WBGene00196294 Y41G9A.14 No description available WB:WBGene00196295 F45H7.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196296 Y39G10AR.27 No description available WB:WBGene00196297 T04D3.9 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00196298 C52A11.5 Is affected by set-2 and etr-1 based on RNA-seq studies. WB:WBGene00196299 Y51H7C.21 No description available WB:WBGene00196300 T04C10.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196301 C11E4.10 No description available WB:WBGene00196302 K08A8.8 Is affected by alg-1 based on RNA-seq studies. WB:WBGene00196303 F10C2.10 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00196304 F09A5.11 No description available WB:WBGene00196305 F56E3.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196306 C54H2.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196307 C26G2.3 No description available WB:WBGene00196308 F49E10.12 No description available WB:WBGene00196309 F53B7.8 No description available WB:WBGene00196310 C07G3.13 No description available WB:WBGene00196311 Y38H6C.27 Is affected by daf-2 based on microarray studies. WB:WBGene00196312 W05E10.8 No description available WB:WBGene00196313 C33F10.17 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00196314 F15A2.9 No description available WB:WBGene00196315 Y24D9A.11 Is affected by several genes including rrf-3; sod-2; and xpo-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00196316 C43C3.6 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00196317 F55F1.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196318 T01C8.8 No description available WB:WBGene00196319 Y45G5AM.10 No description available WB:WBGene00196320 F42A6.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00196321 M79.7 No description available WB:WBGene00196322 R05F9.14 Is affected by adr-1 and etr-1 based on RNA-seq studies. WB:WBGene00196323 F02G3.3 No description available WB:WBGene00196324 Y5H2A.5 Is affected by several genes including blmp-1; emr-1; and adr-1 based on RNA-seq studies. WB:WBGene00196325 ZK617.9 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196326 Y51A2D.26 Is affected by mrps-5 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196327 T05C12.12 No description available WB:WBGene00196328 Y39G8C.6 Is affected by jmjd-5 based on RNA-seq studies. WB:WBGene00196329 C48D5.4 No description available WB:WBGene00196330 ZC190.12 Is affected by let-418 and dlc-1 based on RNA-seq studies. WB:WBGene00196331 B0198.4 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00196332 T27B2.2 No description available WB:WBGene00196333 VB0395L.3 No description available WB:WBGene00196334 F40F12.11 Is affected by cep-1 and fzo-1 based on RNA-seq studies. WB:WBGene00196335 R03A10.8 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00196336 F13B12.13 Enriched in AFD based on RNA-seq studies. Is affected by cep-1 and set-2 based on RNA-seq studies. WB:WBGene00196337 ZK836.6 No description available WB:WBGene00196338 T02E9.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196339 Y37E11AL.13 No description available WB:WBGene00196340 ZK40.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00196341 T27D12.8 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00196342 Y47H9C.17 No description available WB:WBGene00196343 M04D5.4 No description available WB:WBGene00196344 T03F7.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196345 Y73F8A.1163 No description available WB:WBGene00196346 T02E9.13 Enriched in AVK based on RNA-seq studies. Is affected by dlc-1; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00196347 C54D2.9 Enriched in neurons based on RNA-seq studies. Is affected by hpl-2 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196348 R10E12.5 No description available WB:WBGene00196349 F42D1.6 Is affected by pmt-2 based on microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00196350 F01G12.10 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00196351 Y34B4A.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196352 Y22D7AR.17 No description available WB:WBGene00196353 F39B3.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196354 M79.8 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00196355 F22A3.11 No description available WB:WBGene00196356 F43C11.13 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00196357 W02H5.14 Enriched in AFD based on RNA-seq studies. WB:WBGene00196358 Y39D8B.4 No description available WB:WBGene00196359 B0244.13 No description available WB:WBGene00196360 R06C1.7 No description available WB:WBGene00196361 C11G10.4 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00196362 C17F4.13 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00196363 C34H3.6 Enriched in AVK based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196364 C32C4.10 No description available WB:WBGene00196365 C41A3.5 Is affected by Tunicamycin based on microarray studies. WB:WBGene00196366 W02B3.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00196367 C10G11.13 No description available WB:WBGene00196368 Y76A2B.7 Is affected by pmt-2 based on microarray studies. Is affected by Cry5B based on microarray studies. WB:WBGene00196369 F14B8.9 No description available WB:WBGene00196370 F52B10.8 No description available WB:WBGene00196371 B0454.16 No description available WB:WBGene00196372 Y82E9BR.28 No description available WB:WBGene00196373 C30C11.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196374 T21B10.8 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196375 C29E6.11 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and klf-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196376 K02D10.7 Is affected by cep-1 and F01D4.5 based on RNA-seq studies. WB:WBGene00196377 C23H4.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196378 F47E1.10 Is affected by eat-2 based on microarray studies. WB:WBGene00196379 F28F9.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00196380 F11H8.6 No description available WB:WBGene00196381 C32A3.5 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00196382 T05B4.15 No description available WB:WBGene00196383 F48C5.6 No description available WB:WBGene00196384 ZK792.9 No description available WB:WBGene00196385 K11E4.8 No description available WB:WBGene00196386 K02B9.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196387 R04F11.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196388 T23G5.10 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00196389 Y65B4BL.9 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00196390 D1009.8 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00196391 ZK757.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196392 ZC487.7 No description available WB:WBGene00196393 T04F8.11 No description available WB:WBGene00196394 T06A4.5 No description available WB:WBGene00196395 Y111B2A.33 Enriched in AFD and ASER based on RNA-seq studies. WB:WBGene00196396 F31C3.14 Is affected by several genes including prg-1; ins-11; and meg-3 based on RNA-seq and microarray studies. WB:WBGene00196397 F48C1.12 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; alg-1; and lag-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00196398 W10D5.4 Is affected by pmt-2 and etr-1 based on microarray and RNA-seq studies. Is affected by Tunicamycin and Oligosaccharides based on microarray studies. WB:WBGene00196399 T14F9.9 Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq studies. WB:WBGene00196400 Y73F8A.1164 No description available WB:WBGene00196401 F27B10.2 No description available WB:WBGene00196402 F10C1.13 No description available WB:WBGene00196403 F33C8.6 No description available WB:WBGene00196404 F58H7.9 No description available WB:WBGene00196405 K08E5.9 No description available WB:WBGene00196406 C16C2.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196407 T13H2.7 Enriched in AFD and PLM based on RNA-seq studies. WB:WBGene00196408 F15G9.7 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00196409 K03H9.7 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq and microarray studies. WB:WBGene00196410 R02E12.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196411 T10H10.4 Is affected by daf-2 based on microarray studies. WB:WBGene00196412 Y66D12A.27 Enriched in neurons based on RNA-seq studies. WB:WBGene00196413 C06B8.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196414 B0034.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196415 C54G7.7 No description available WB:WBGene00196416 D1079.2 Enriched in neurons based on RNA-seq studies. WB:WBGene00196417 K02F2.8 Enriched in neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00196418 Y53C10A.17 Is affected by daf-2 based on microarray studies. WB:WBGene00196419 ZK381.40 No description available WB:WBGene00196420 ZK652.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00196421 F09C3.7 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196422 ZC64.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196423 F56H11.9 Is affected by ifo-1 based on microarray studies. WB:WBGene00196424 F54E4.8 Is affected by eat-2 based on microarray studies. WB:WBGene00196425 F42D1.7 Is affected by adr-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196426 R02E12.10 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196427 K10B4.8 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00196428 Y37E3.27 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00196429 F18G5.8 No description available WB:WBGene00196430 Y75B8A.46 No description available WB:WBGene00196431 F53F8.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00196432 T14G11.5 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00196433 C40H5.11 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00196434 K06C4.19 Is affected by meg-3 and meg-4 based on RNA-seq studies. WB:WBGene00196435 C41G11.7 Enriched in neurons based on RNA-seq studies. Is affected by daf-12 based on RNA-seq studies. WB:WBGene00196436 C01B7.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196437 F37B12.7 Is affected by eat-2 based on microarray studies. WB:WBGene00196438 Y39B6A.72 No description available WB:WBGene00196439 Y57A10B.9 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00196440 K04A8.12 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00196441 K01A6.12 No description available WB:WBGene00196442 T21B10.9 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1; ifo-1; and hda-2 based on RNA-seq and microarray studies. WB:WBGene00196443 C04H4.3 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00196444 F47E1.11 No description available WB:WBGene00196445 F15A8.18 No description available WB:WBGene00196446 F52B10.9 No description available WB:WBGene00196447 F46C8.10 Is affected by cep-1; nfki-1; and etr-1 based on RNA-seq studies. WB:WBGene00196448 Y59A8B.28 No description available WB:WBGene00196449 Y75B7AL.5 Enriched in AFD; ASER; and PLM based on RNA-seq studies. Is affected by daf-16 based on RNA-seq studies. WB:WBGene00196450 F20B10.6 No description available WB:WBGene00196451 K04A8.13 No description available WB:WBGene00196452 Y66D12A.28 No description available WB:WBGene00196453 F27D9.10 No description available WB:WBGene00196454 M01H9.8 No description available WB:WBGene00196455 C34F6.15 No description available WB:WBGene00196456 F18E9.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196457 C46C11.5 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196458 Y45G5AM.11 No description available WB:WBGene00196459 R151.14 No description available WB:WBGene00196460 F45E1.8 No description available WB:WBGene00196461 C10G6.51 No description available WB:WBGene00196462 C11G10.5 No description available WB:WBGene00196463 F08F1.11 No description available WB:WBGene00196464 F35D2.8 Is affected by cep-1 and let-418 based on RNA-seq studies. WB:WBGene00196465 Y51F10.12 No description available WB:WBGene00196466 H21P03.5 No description available WB:WBGene00196467 F43C9.5 No description available WB:WBGene00196468 W09G3.12 No description available WB:WBGene00196469 F08F3.13 Is affected by tdp-1; set-2; and hlh-26 based on RNA-seq studies. Is affected by stavudine and Zidovudine based on RNA-seq studies. WB:WBGene00196470 R05D3.13 No description available WB:WBGene00196471 F57B1.10 Is affected by cox-5B based on RNA-seq studies. WB:WBGene00196472 H08J11.4 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00196473 Y70D2A.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00196474 K01A12.5 Is affected by hmg-3 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196475 F07C3.12 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196476 C34H3.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196477 F57B1.11 No description available WB:WBGene00196478 T09D3.11 No description available WB:WBGene00196479 Y39G10AR.28 No description available WB:WBGene00196480 C27A12.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196481 F56D12.9 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00196482 T25D1.4 No description available WB:WBGene00196483 W05E10.9 No description available WB:WBGene00196484 ZK994.9 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00196485 C16D9.12 Is affected by daf-2; nhr-86; and lag-1 based on microarray and RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00196486 C48D5.5 No description available WB:WBGene00196487 C18A3.15 No description available WB:WBGene00196488 K06G5.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196489 C15B12.10 Enriched in neurons based on RNA-seq studies. Is affected by spr-5 based on RNA-seq studies. WB:WBGene00196490 C03C10.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196491 M03F8.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196492 C34C12.10 No description available WB:WBGene00196493 ZK973.15 Is affected by several genes including eat-2; cep-1; and dpy-21 based on RNA-seq and microarray studies. WB:WBGene00196494 C07A12.9 No description available WB:WBGene00196495 T22B7.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196496 C09D8.5 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00196497 ZK525.5 No description available WB:WBGene00196498 B0350.71 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196499 F38B6.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00196500 T11F9.23 Is affected by cep-1; meg-3; and meg-4 based on RNA-seq studies. WB:WBGene00196501 T28B11.8 Enriched in AVK based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196502 R05D7.8 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196503 F14H12.11 Is affected by daf-2 based on microarray studies. WB:WBGene00196504 C05C9.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00196505 F42H10.11 No description available WB:WBGene00196506 C35C5.13 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196507 F31F6.9 No description available WB:WBGene00196508 T06G6.14 No description available WB:WBGene00196509 F25B4.11 Is affected by cep-1; adr-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196510 F52H2.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196511 C48C5.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196512 C03F11.6 No description available WB:WBGene00196513 Y57G11C.1137 No description available WB:WBGene00196514 F44G3.18 No description available WB:WBGene00196515 B0457.9 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00196516 F35D2.9 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00196517 Y71F9B.18 No description available WB:WBGene00196518 H01G02.6 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196519 C08F8.10 No description available WB:WBGene00196520 Y105C5A.1275 No description available WB:WBGene00196521 C18A3.16 No description available WB:WBGene00196522 Y32F6A.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00196523 C04H4.4 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00196524 C10C5.10 No description available WB:WBGene00196525 C47G2.12 No description available WB:WBGene00196526 R07B1.16 No description available WB:WBGene00196527 F55A8.4 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00196528 C34B4.10 No description available WB:WBGene00196529 K11G9.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00196530 Y60A3A.32 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196531 C49F8.7 No description available WB:WBGene00196532 R07B1.17 No description available WB:WBGene00196533 F33D11.14 No description available WB:WBGene00196534 Y113G7A.18 No description available WB:WBGene00196535 C02B10.72 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00196536 H24G06.2 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196537 F58B4.9 Enriched in AVK based on RNA-seq studies. WB:WBGene00196538 C09F12.6 Is affected by several genes including set-2; adr-1; and hmg-3 based on RNA-seq studies. WB:WBGene00196539 M03D4.75 No description available WB:WBGene00196540 Y37E11B.13 No description available WB:WBGene00196541 R10F2.7 No description available WB:WBGene00196542 C44B7.15 Is affected by prg-1 and etr-1 based on RNA-seq studies. WB:WBGene00196543 C52B9.14 No description available WB:WBGene00196544 F40G12.16 No description available WB:WBGene00196545 C26B2.11 No description available WB:WBGene00196546 F38A3.3 Is affected by cep-1 and nfki-1 based on RNA-seq studies. WB:WBGene00196547 R04F11.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00196548 Y60A3A.33 No description available WB:WBGene00196549 F55C12.9 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00196550 C24A8.8 No description available WB:WBGene00196551 F15D3.11 No description available WB:WBGene00196552 F09G2.11 Is affected by eat-2 based on microarray studies. WB:WBGene00196553 T05C1.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00196554 B0563.13 No description available WB:WBGene00196555 R11B5.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00196556 F31B12.5 No description available WB:WBGene00196557 B0432.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00196558 C33G3.9 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196559 F35G2.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196560 C35C5.14 Is affected by pmt-2 based on microarray studies. WB:WBGene00196561 Y38A10A.9 Is affected by daf-2 based on microarray studies. WB:WBGene00196562 C56E6.14 Is affected by daf-2 based on microarray studies. WB:WBGene00196563 ZK675.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196564 F36H1.14 No description available WB:WBGene00196565 F56F3.9 No description available WB:WBGene00196566 F47G6.6 No description available WB:WBGene00196567 H22K11.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196568 M79.9 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00196569 C54H2.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00196570 M195.5 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00196571 T06E4.17 No description available WB:WBGene00196572 Y75B8A.47 No description available WB:WBGene00196573 M163.16 Is affected by several genes including eat-2; tph-1; and cep-1 based on RNA-seq and microarray studies. Is affected by Cry5B based on microarray studies. WB:WBGene00196574 F12D9.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196575 F29G9.9 Is affected by dlc-1; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00196576 C46A5.13 Is affected by Cry5B and silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196577 T28D6.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196578 F55C12.10 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00196579 C06G1.8 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00196580 F26C11.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00196581 M117.10 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00196582 F08B12.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196583 R13A1.14 No description available WB:WBGene00196584 C14F11.10 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196585 C40C9.10 No description available WB:WBGene00196586 C04A2.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196587 Y76F7A.1 No description available WB:WBGene00196588 W06H8.10 Is affected by cep-1; adr-1; and etr-1 based on RNA-seq studies. WB:WBGene00196589 B0495.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00196590 B0035.19 No description available WB:WBGene00196591 F47B7.11 Is affected by several genes including alg-1; hda-2; and etr-1 based on RNA-seq studies. WB:WBGene00196592 T24D8.11 No description available WB:WBGene00196593 C03F11.7 No description available WB:WBGene00196594 F28F9.11 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq studies. WB:WBGene00196595 R03A10.9 Is affected by Cry5B based on microarray studies. WB:WBGene00196596 T03G11.16 No description available WB:WBGene00196597 F12D9.10 No description available WB:WBGene00196598 R186.10 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00196599 M01H9.9 No description available WB:WBGene00196600 E04D5.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196601 Y110A2AL.17 Is affected by nhr-86 based on RNA-seq studies. WB:WBGene00196602 W05E10.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196603 C13G3.5 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. WB:WBGene00196604 T03G6.5 Is affected by daf-2 based on microarray studies. WB:WBGene00196605 W06B3.3 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00196606 Y15E3A.7 Is affected by several genes including daf-2; cep-1; and fzo-1 based on RNA-seq and microarray studies. WB:WBGene00196607 F40F8.13 Is affected by Tunicamycin based on microarray studies. WB:WBGene00196608 F58A4.17 No description available WB:WBGene00196609 F25G6.14 Is affected by daf-2 based on microarray studies. WB:WBGene00196610 W09C5.13 No description available WB:WBGene00196611 F40F9.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196612 F42E8.3 No description available WB:WBGene00196613 T28B4.7 Is affected by daf-2 based on microarray studies. WB:WBGene00196614 C41G11.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00196615 F53F4.21 No description available WB:WBGene00196616 F01E11.8 Is affected by hmg-4; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00196617 C50H2.15 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00196618 F59D12.9 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00196619 C04A11.6 No description available WB:WBGene00196620 T11F9.24 No description available WB:WBGene00196621 Y92C3A.5 No description available WB:WBGene00196622 F29D11.3 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00196623 F09C8.4 No description available WB:WBGene00196624 Y47C4A.2 No description available WB:WBGene00196625 T28C12.8 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196626 F22E10.8 No description available WB:WBGene00196627 H08J11.5 No description available WB:WBGene00196628 C34C12.11 No description available WB:WBGene00196629 T12B3.7 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196630 F09D5.1 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00196631 F26D11.15 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00196632 F22F4.8 No description available WB:WBGene00196633 M01G4.4 No description available WB:WBGene00196634 K03C7.6 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196635 F31F7.5 Is affected by camt-1 based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00196636 C27C7.10 No description available WB:WBGene00196637 F52H2.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00196638 F14B4.4 No description available WB:WBGene00196639 T22C1.14 Enriched in neurons based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00196640 T25D3.5 Is affected by several genes including cep-1; let-418; and mrps-5 based on RNA-seq studies. WB:WBGene00196641 F45E1.9 No description available WB:WBGene00196642 F52B10.10 No description available WB:WBGene00196643 F45B8.9 No description available WB:WBGene00196644 K08H10.15 Is affected by hmg-3 and daf-2 based on RNA-seq and microarray studies. Is affected by 4-bromodiphenyl ether and Tunicamycin based on microarray studies. WB:WBGene00196645 C34D10.3 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00196646 C33D12.10 No description available WB:WBGene00196647 T19D12.12 Is affected by dpy-21 and adr-2 based on RNA-seq studies. WB:WBGene00196648 K03B8.16 No description available WB:WBGene00196649 F42H10.12 No description available WB:WBGene00196650 H01G02.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00196651 T01C1.7 No description available WB:WBGene00196652 W01H2.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196653 R04F11.11 No description available WB:WBGene00196654 ZC53.9 No description available WB:WBGene00196655 ZC250.7 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00196656 M02D8.9 Is affected by pmt-2 based on microarray studies. WB:WBGene00196657 T19D7.9 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00196658 C48B6.12 No description available WB:WBGene00196659 F23H12.14 No description available WB:WBGene00196660 T28B11.9 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196661 W03G11.9 Is affected by pgrn-1 and cep-1 based on RNA-seq studies. WB:WBGene00196662 Y76F7A.2 Enriched in neurons based on RNA-seq studies. WB:WBGene00196663 W03G11.10 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00196664 ZC53.10 No description available WB:WBGene00196665 R173.7 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00196666 T22C8.9 No description available WB:WBGene00196667 cTel7X.2 No description available WB:WBGene00196668 K11H12.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00196669 Y47D3B.14 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00196670 ZK507.7 No description available WB:WBGene00196671 ZK973.16 No description available WB:WBGene00196672 F57G12.4 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196673 ZK897.9 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00196674 C15A7.5 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00196675 B0403.8 Is affected by ints-9 based on RNA-seq studies. WB:WBGene00196676 T14F9.10 No description available WB:WBGene00196677 C34D1.7 No description available WB:WBGene00196678 D2023.13 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196679 F10G8.11 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196680 F13D11.9 No description available WB:WBGene00196681 M03F4.10 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196682 F15A2.10 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196683 F41D9.9 No description available WB:WBGene00196684 F59D8.3 Is affected by several genes including daf-2; cep-1; and lem-2 based on RNA-seq and microarray studies. Is affected by Ethanol and fluvastatin based on RNA-seq studies. WB:WBGene00196685 T14F9.11 No description available WB:WBGene00196686 F42E11.5 No description available WB:WBGene00196687 C09B8.12 Is affected by several genes including spr-5; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00196688 B0250.15 Is affected by elli-1; fzo-1; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00196689 C26B2.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196690 F20A1.12 Is affected by dpy-21 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196691 M02D8.10 Is affected by pgrn-1; cep-1; and set-2 based on RNA-seq studies. WB:WBGene00196692 Y73B3A.24 Is affected by damt-1 based on RNA-seq studies. Is affected by Ethanol and antimycin based on RNA-seq studies. WB:WBGene00196693 F11C1.12 No description available WB:WBGene00196694 C29H12.8 No description available WB:WBGene00196695 T14G10.9 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196696 H06I04.11 No description available WB:WBGene00196697 C02B4.5 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00196698 F42D1.8 No description available WB:WBGene00196699 C52G5.5 No description available WB:WBGene00196700 F54E4.9 Is affected by daf-2 based on microarray studies. WB:WBGene00196701 ZC455.15 Is affected by daf-16 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00196702 T12A7.11 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by klf-1 and etr-1 based on RNA-seq studies. WB:WBGene00196703 F32B4.9 No description available WB:WBGene00196704 C52B9.15 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196705 ZC328.6 No description available WB:WBGene00196706 F35A5.9 Is affected by pmt-2 based on microarray studies. WB:WBGene00196707 B0393.12 No description available WB:WBGene00196708 K08A8.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196709 T04C12.18 Enriched in neurons based on RNA-seq studies. Is affected by alg-1; adr-1; and camt-1 based on RNA-seq studies. WB:WBGene00196710 T21C9.14 No description available WB:WBGene00196711 ZK892.9 No description available WB:WBGene00196712 F22B5.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196713 F18A12.9 No description available WB:WBGene00196714 M153.6 No description available WB:WBGene00196715 F46F3.7 No description available WB:WBGene00196716 ZK899.9 No description available WB:WBGene00196717 Y105E8A.39 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196718 F49D11.12 Is affected by daf-2 based on microarray studies. WB:WBGene00196719 K09F5.7 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00196720 ZC247.5 No description available WB:WBGene00196721 F57B10.17 Is affected by several genes including cep-1; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00196722 Y60A9A.4 No description available WB:WBGene00196723 F53B3.9 Is affected by cep-1 and lpd-3 based on RNA-seq studies. WB:WBGene00196724 T27F2.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00196725 Y66A7AL.2 No description available WB:WBGene00196726 T08H4.6 No description available WB:WBGene00196727 T05A6.9 Is affected by daf-2 based on microarray studies. WB:WBGene00196728 C27C12.8 Is affected by cep-1 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00196729 K04D7.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196730 F14D1.1 Enriched in neurons based on RNA-seq studies. Is affected by alg-1 based on RNA-seq studies. WB:WBGene00196731 C09G1.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196732 H12I19.116 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196733 ZK381.41 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00196734 C07A4.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196735 T28B11.10 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00196736 R74.9 No description available WB:WBGene00196737 T28B4.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and ikb-1 based on RNA-seq studies. WB:WBGene00196738 F18E2.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196739 C13C12.5 No description available WB:WBGene00196740 H35B03.23 No description available WB:WBGene00196741 C18B2.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00196742 T01B6.6 No description available WB:WBGene00196743 K10C3.9 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00196744 Y73B6BL.274 No description available WB:WBGene00196745 H05G16.3 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196746 C02H7.4 No description available WB:WBGene00196747 Y53G8AR.10 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by glycine and cadmium based on RNA-seq studies. WB:WBGene00196748 F13H8.13 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00196749 F54D12.14 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196750 Y51H7BR.10 No description available WB:WBGene00196751 K08B12.7 Enriched in neurons based on RNA-seq studies. Is affected by daf-2; pmt-2; and camt-1 based on microarray and RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196752 T06D8.12 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196753 W06B11.6 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00196754 F35E2.12 No description available WB:WBGene00196755 F29G6.4 No description available WB:WBGene00196756 C36F7.9 No description available WB:WBGene00196757 F54D12.15 No description available WB:WBGene00196758 Y69E1A.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196759 F58H1.12 Is affected by daf-2 based on microarray studies. WB:WBGene00196760 T23G4.126 No description available WB:WBGene00196761 C54A12.5 No description available WB:WBGene00196762 K08A2.11 No description available WB:WBGene00196763 T20B5.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00196764 C45B2.10 No description available WB:WBGene00196765 K08A8.10 Is affected by cep-1 and let-418 based on RNA-seq studies. WB:WBGene00196766 W05E10.11 No description available WB:WBGene00196767 K01A6.13 No description available WB:WBGene00196768 ZK909.7 Is affected by lem-2; emr-1; and dpy-21 based on RNA-seq studies. WB:WBGene00196769 B0457.10 Is affected by adr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196770 F09B12.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196771 F54A3.8 No description available WB:WBGene00196772 ZK813.9 Is affected by adr-1 and lpd-3 based on RNA-seq studies. WB:WBGene00196773 ZC84.9 No description available WB:WBGene00196774 Y40C5A.15 No description available WB:WBGene00196775 F58G11.7 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196776 F55G11.13 No description available WB:WBGene00196777 T19A5.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196778 F26D12.99 No description available WB:WBGene00196779 C15C7.10 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00196780 C17E4.15 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; etr-1; and lpd-3 based on RNA-seq studies. WB:WBGene00196781 Y65B4BL.10 Enriched in AFD based on RNA-seq studies. WB:WBGene00196782 T26C12.7 No description available WB:WBGene00196783 F25F2.3 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196784 T22E5.11 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196785 ZK328.10 No description available WB:WBGene00196786 R12C12.11 No description available WB:WBGene00196787 C14B9.12 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00196788 C25A11.5 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00196789 ZC64.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196790 F38B7.13 Is affected by Tunicamycin based on microarray studies. WB:WBGene00196791 W01B11.7 No description available WB:WBGene00196792 C11D2.99 No description available WB:WBGene00196793 C04C11.9 Is affected by cep-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00196794 Y39B6A.73 No description available WB:WBGene00196795 C06E7.89 No description available WB:WBGene00196796 W10C8.9 No description available WB:WBGene00196797 C02D4.5 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00196798 F59C12.7 Is affected by daf-2 based on microarray studies. WB:WBGene00196799 R13H4.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196800 C43G2.26 No description available WB:WBGene00196801 W02B8.7 No description available WB:WBGene00196802 C36F7.10 No description available WB:WBGene00196803 C18E9.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196804 C45B2.11 No description available WB:WBGene00196805 F45D3.8 No description available WB:WBGene00196806 F39C12.6 Is affected by daf-2 based on microarray studies. WB:WBGene00196807 T01B6.7 No description available WB:WBGene00196808 ZK678.10 No description available WB:WBGene00196809 T10B10.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00196810 W06B11.7 Is affected by dpy-21 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00196811 F58H1.13 Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00196812 Y39B6A.74 No description available WB:WBGene00196813 Y37A1B.331 No description available WB:WBGene00196814 F14F3.8 Enriched in neurons based on RNA-seq studies. Is affected by alg-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00196815 F40E10.8 No description available WB:WBGene00196816 T27E4.15 Is affected by pmt-2 and etr-1 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00196817 Y54G2A.60 Enriched in neurons based on RNA-seq studies. WB:WBGene00196818 F25B5.9 Is affected by adr-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00196819 F31E8.10 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; cep-1; and met-2 based on RNA-seq and microarray studies. WB:WBGene00196820 F46C8.11 Is affected by set-2; hda-2; and xpf-1 based on RNA-seq studies. WB:WBGene00196821 F29C4.9 No description available WB:WBGene00196822 T19C4.19 Is affected by pmt-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00196823 Y54G9A.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00196824 F11A6.7 Enriched in neurons based on RNA-seq studies. Is affected by ifo-1 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196825 C53A5.18 No description available WB:WBGene00196826 B0350.72 No description available WB:WBGene00196827 C17C3.22 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00196828 C40C9.11 Is affected by daf-2 based on microarray studies. WB:WBGene00196829 T23B12.12 No description available WB:WBGene00196830 F40H3.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196831 H35N03.2 Enriched in neurons based on RNA-seq studies. Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00196832 F08H9.13 Is affected by etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196833 C27A2.10 No description available WB:WBGene00196834 C24B5.8 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00196835 T11F9.25 No description available WB:WBGene00196836 C26E1.5 No description available WB:WBGene00196837 C17D12.11 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196838 F55C5.14 Is affected by cep-1 and lpd-3 based on RNA-seq studies. WB:WBGene00196839 F19H6.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196840 K10D6.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196841 F25H10.2 Enriched in neurons based on RNA-seq studies. WB:WBGene00196842 DH11.7 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00196843 C41G11.9 Enriched in head mesodermal cell and sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196844 Y22F5A.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196845 W02F12.10 Is affected by adr-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00196846 T22D1.19 No description available WB:WBGene00196847 Y39A3CL.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00196848 ZK353.11 Enriched in neurons based on RNA-seq studies. Is affected by hpl-2 and etr-1 based on RNA-seq studies. WB:WBGene00196849 T10E10.9 No description available WB:WBGene00196850 F09F9.8 No description available WB:WBGene00196851 Y38C1AA.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00196852 C02F4.10 Enriched in AVK; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; dlc-1; and adr-1 based on RNA-seq and microarray studies. WB:WBGene00196853 T07F10.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196854 CD4.13 Enriched in neurons based on RNA-seq studies. Is affected by set-2; etr-1; and hlh-26 based on RNA-seq studies. WB:WBGene00196855 ZK381.42 Is affected by alg-1 and bcat-1 based on RNA-seq studies. WB:WBGene00196856 R10E11.10 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196857 VB0365.2 Enriched in neurons based on RNA-seq studies. WB:WBGene00196858 C30C11.7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00196859 C47D12.9 No description available WB:WBGene00196860 T02E9.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00196861 F41H10.36 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196862 K02A4.3 No description available WB:WBGene00196863 F52E10.8 Is affected by daf-2 and set-2 based on microarray and RNA-seq studies. WB:WBGene00196864 F45H7.10 No description available WB:WBGene00196865 F58B6.6 No description available WB:WBGene00196866 C31G12.7 No description available WB:WBGene00196867 ZC477.16 Is affected by daf-2 based on microarray studies. WB:WBGene00196868 C35A11.6 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196869 R01E6.10 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196870 D1044.10 No description available WB:WBGene00196871 K11C4.8 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; lem-2; and ahr-1 based on RNA-seq studies. WB:WBGene00196872 F40F9.15 Enriched in AVK based on RNA-seq studies. Is affected by several genes including daf-2; cep-1; and etr-1 based on RNA-seq and microarray studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00196873 C41G11.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00196874 C18A3.17 No description available WB:WBGene00196875 Y104H12D.5 No description available WB:WBGene00196876 C14F11.11 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00196877 W01A11.10 Is affected by cep-1 and hlh-26 based on RNA-seq studies. WB:WBGene00196878 Y55F3C.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196879 C30F8.6 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00196880 Y71A12B.27 No description available WB:WBGene00196881 Y71F9AR.6 No description available WB:WBGene00196882 C55A6.16 No description available WB:WBGene00196883 F43E12.2 No description available WB:WBGene00196884 C54D1.9 Is affected by several genes including cep-1; let-418; and chd-3 based on RNA-seq studies. WB:WBGene00196885 ZC513.15 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00196886 K02A2.8 No description available WB:WBGene00196887 R04F11.12 No description available WB:WBGene00196888 T07D1.9 Is affected by chd-3 based on RNA-seq studies. WB:WBGene00196889 C35A5.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00196890 Y105E8B.13 No description available WB:WBGene00196891 R90.6 No description available WB:WBGene00196892 C18D1.12 Is affected by mrps-5 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00196893 F13H6.7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00196894 F47F2.4 No description available WB:WBGene00196895 T06H11.8 No description available WB:WBGene00196896 Y39G8C.7 No description available WB:WBGene00196897 C49A1.12 No description available WB:WBGene00196898 C14C11.9 No description available WB:WBGene00196899 Y43F8A.7 No description available WB:WBGene00196900 C02B10.73 No description available WB:WBGene00196901 Y51A2D.27 No description available WB:WBGene00196902 C10F3.11 No description available WB:WBGene00196903 M01E11.9 Is affected by cep-1 and mrps-5 based on RNA-seq studies. WB:WBGene00196904 Y43E12A.4 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196905 C30A5.12 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00196906 F08G5.11 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00196907 F22G12.9 Is affected by pmt-2 based on microarray studies. WB:WBGene00196908 F09E5.19 No description available WB:WBGene00196909 Y34B4A.14 No description available WB:WBGene00196910 H14A12.8 No description available WB:WBGene00196911 C53B7.10 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00196912 W02A2.11 No description available WB:WBGene00196913 F56D1.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196914 R07E4.9 Is affected by cep-1; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00196915 F56H11.10 No description available WB:WBGene00196916 C56G2.17 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00196917 B0379.10 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00196918 F49E10.13 Is affected by cep-1; daf-2; and set-2 based on RNA-seq and microarray studies. WB:WBGene00196919 R07B1.18 No description available WB:WBGene00196920 C34H3.8 No description available WB:WBGene00196921 Y75B8A.48 Enriched in neurons based on RNA-seq studies. WB:WBGene00196922 R02D5.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00196923 F57F4.5 No description available WB:WBGene00196924 D1053.5 No description available WB:WBGene00196925 ZC504.8 No description available WB:WBGene00196926 Y39G8B.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196927 C41A3.6 No description available WB:WBGene00196928 F26F12.9 No description available WB:WBGene00196929 C35C5.15 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196930 F44E5.7 No description available WB:WBGene00196931 B0001.10 Enriched in AFD based on RNA-seq studies. WB:WBGene00196932 Y17D7B.12 No description available WB:WBGene00196933 F43D9.8 Is affected by several genes including cep-1; pmt-2; and tdp-1 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00196934 C54G6.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00196935 F13H6.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00196936 F25H8.9 No description available WB:WBGene00196937 T01C1.8 Enriched in neurons based on RNA-seq studies. Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00196938 F49H12.9 No description available WB:WBGene00196939 C18D1.13 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00196940 Y38H8A.10 No description available WB:WBGene00196941 EGAP7.2 No description available WB:WBGene00196942 C15C8.10 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196943 T13H10.7 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00196944 T01C3.12 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196945 F52D10.7 No description available WB:WBGene00196946 F57C7.8 Is affected by cep-1; adr-1; and ints-4 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196947 K02G10.9 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00196948 F08C6.11 No description available WB:WBGene00196949 C47G2.13 No description available WB:WBGene00196950 T28D9.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00196951 C54G7.8 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00196952 R07B1.19 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196953 F59D12.10 Is affected by met-2 and spr-5 based on RNA-seq studies. Is affected by sodium arsenite based on RNA-seq studies. WB:WBGene00196954 R106.4 No description available WB:WBGene00196955 F20A1.13 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196956 C52E4.14 Is affected by set-2 based on RNA-seq studies. WB:WBGene00196957 ZK682.8 Is affected by daf-2 based on microarray studies. WB:WBGene00196958 F58A4.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196959 C49F8.8 Is affected by fzo-1 and etr-1 based on RNA-seq studies. WB:WBGene00196960 R13F6.11 Is affected by mrps-5 based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00196961 F20D1.13 No description available WB:WBGene00196962 H34C03.18 Is affected by camt-1 and etr-1 based on RNA-seq studies. WB:WBGene00196963 Y47H9A.4 Is affected by pmt-2 based on microarray studies. Is affected by 4-bromodiphenyl ether based on microarray studies. WB:WBGene00196964 F55F3.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00196965 F16F9.7 No description available WB:WBGene00196966 C47C12.7 No description available WB:WBGene00196967 F14B8.10 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00196968 R06F6.13 No description available WB:WBGene00196969 R03E9.6 Enriched in neurons based on RNA-seq studies. Is affected by set-2 and etr-1 based on RNA-seq studies. WB:WBGene00196970 B0304.10 No description available WB:WBGene00196971 F52B10.11 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00196972 F22B3.13 No description available WB:WBGene00196973 F42A10.12 Is affected by daf-2; dpy-21; and elli-1 based on RNA-seq and microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00196974 F41C6.9 No description available WB:WBGene00196975 Y94H6A.13 No description available WB:WBGene00196976 Y104H12D.6 No description available WB:WBGene00196977 C42D8.12 No description available WB:WBGene00196978 Y53H1C.7 No description available WB:WBGene00196979 F09F9.9 Is affected by daf-2 based on microarray studies. WB:WBGene00196980 H16O14.76 No description available WB:WBGene00196981 C06E1.13 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00196982 Y41C4A.24 No description available WB:WBGene00196983 C07H6.12 No description available WB:WBGene00196984 F09F3.15 No description available WB:WBGene00196985 F35G2.12 Is affected by hpl-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00196986 H01A20.2 Is affected by several genes including cep-1; sma-2; and met-2 based on microarray and RNA-seq studies. WB:WBGene00196987 C25E10.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196988 F32A11.8 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00196989 F12F6.14 No description available WB:WBGene00196990 K04A8.14 No description available WB:WBGene00196991 F26A10.10 No description available WB:WBGene00196992 F54H5.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00196993 F15C11.5 No description available WB:WBGene00196994 T01H3.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196995 Y55F3BR.14 No description available WB:WBGene00196996 F46E10.14 Is affected by cep-1; dlc-1; and ifo-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00196997 F55C5.15 No description available WB:WBGene00196998 F21A3.9 Enriched in neurons based on RNA-seq studies. Is affected by klf-1 based on RNA-seq studies. WB:WBGene00196999 F07B7.16 No description available WB:WBGene00197000 C34H3.9 No description available WB:WBGene00197001 C13C4.9 No description available WB:WBGene00197002 F33D4.12 Is affected by Tunicamycin based on microarray studies. WB:WBGene00197003 K07C10.5 No description available WB:WBGene00197004 F53B2.13 No description available WB:WBGene00197005 K02A11.6 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00197006 W05B2.11 No description available WB:WBGene00197007 C33B4.9 Is affected by spt-16 based on RNA-seq studies. WB:WBGene00197008 C05C9.7 Is affected by hmg-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00197009 F18E2.10 No description available WB:WBGene00197010 C32C4.11 Is affected by pmt-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00197011 F09C12.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00197012 Y40C5A.16 No description available WB:WBGene00197013 F58H1.14 Is affected by several genes including daf-2; daf-12; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00197014 C34B2.13 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00197015 AH10.7 No description available WB:WBGene00197016 K10D6.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197017 F25G6.15 No description available WB:WBGene00197018 H30A04.2 No description available WB:WBGene00197019 Y38H6A.6 No description available WB:WBGene00197020 F08G5.12 No description available WB:WBGene00197021 M01G5.8 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00197022 Y53F4B.54 No description available WB:WBGene00197023 Y67D8A.7 Is affected by several genes including cep-1; set-2; and dlc-1 based on RNA-seq studies. WB:WBGene00197024 F56E3.9 Enriched in AVK based on RNA-seq studies. WB:WBGene00197025 C14F5.7 No description available WB:WBGene00197026 Y71A12B.28 No description available WB:WBGene00197027 C52B9.16 No description available WB:WBGene00197028 ZC64.10 No description available WB:WBGene00197029 Y39B6A.75 No description available WB:WBGene00197030 T01B10.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; daf-2; and camt-1 based on RNA-seq and microarray studies. WB:WBGene00197031 F35H8.9 Is affected by mrps-5 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197032 F47G4.10 No description available WB:WBGene00197033 T24B8.10 Enriched in AVK based on RNA-seq studies. Is affected by cep-1; elli-1; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00197034 C01F4.5 No description available WB:WBGene00197035 F47G4.11 No description available WB:WBGene00197036 E02A10.7 Enriched in neurons based on RNA-seq studies. Is affected by hda-2 based on RNA-seq studies. WB:WBGene00197037 K01G5.11 Is affected by cep-1 and mrps-5 based on RNA-seq studies. WB:WBGene00197038 F09D5.2 Enriched in neurons based on RNA-seq studies. WB:WBGene00197039 Y55B1BR.7 Enriched in AFD; ASER; and PLM based on RNA-seq studies. Is affected by daf-16 and camt-1 based on RNA-seq studies. WB:WBGene00197040 ZC477.17 No description available WB:WBGene00197041 F56B3.13 Is affected by swsn-1 based on RNA-seq studies. WB:WBGene00197042 R13F6.12 No description available WB:WBGene00197043 C30G4.8 No description available WB:WBGene00197044 C36F7.11 No description available WB:WBGene00197045 C29A12.9 No description available WB:WBGene00197046 T24B8.11 No description available WB:WBGene00197047 B0334.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197048 C04D8.2 Is affected by several genes including daf-2; let-418; and dlc-1 based on RNA-seq and microarray studies. WB:WBGene00197049 Y53F4A.4 No description available WB:WBGene00197050 K08E5.10 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197051 2RSSE.5 No description available WB:WBGene00197052 F13D11.10 Is affected by cep-1; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00197053 F22E12.6 No description available WB:WBGene00197054 ZK512.13 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00197055 T14G11.6 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00197056 VT21B10L.1 No description available WB:WBGene00197057 C06A6.9 No description available WB:WBGene00197058 ZK617.10 No description available WB:WBGene00197059 T23H2.6 No description available WB:WBGene00197060 T03E6.13 Is affected by Tunicamycin based on microarray studies. WB:WBGene00197061 C14F11.12 No description available WB:WBGene00197062 Y54E10A.21 Is affected by pmt-2; met-2; and spr-5 based on microarray and RNA-seq studies. WB:WBGene00197063 F55A12.12 No description available WB:WBGene00197064 C02C6.5 Enriched in neurons based on RNA-seq studies. Is affected by alh-4 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197065 M28.13 No description available WB:WBGene00197066 F13H6.9 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00197067 T27B1.3 No description available WB:WBGene00197068 F40H3.9 No description available WB:WBGene00197069 Y38F2AR.16 No description available WB:WBGene00197070 C35B8.6 No description available WB:WBGene00197071 K12H6.14 No description available WB:WBGene00197072 ZK867.9 Enriched in neurons based on RNA-seq studies. Is affected by daf-12 and etr-1 based on RNA-seq studies. WB:WBGene00197073 ZK836.7 No description available WB:WBGene00197074 C30B5.11 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197075 C01F6.12 No description available WB:WBGene00197076 C03C11.5 No description available WB:WBGene00197077 F14H12.12 No description available WB:WBGene00197078 F44E7.13 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00197079 C16B8.6 No description available WB:WBGene00197080 ZC15.11 Is affected by several genes including daf-2; eat-2; and sma-2 based on RNA-seq and microarray studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00197081 C29A12.10 No description available WB:WBGene00197082 R03D7.11 Is affected by pmt-2 based on microarray studies. WB:WBGene00197083 C16D9.13 Is affected by several genes including daf-2; eat-2; and set-2 based on microarray and RNA-seq studies. WB:WBGene00197084 Y39G10AR.29 No description available WB:WBGene00197085 C04H4.5 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197086 T21B6.9 No description available WB:WBGene00197087 F25H10.3 No description available WB:WBGene00197088 Y113G7C.2 No description available WB:WBGene00197089 Y60A3A.34 No description available WB:WBGene00197090 T14D7.4 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00197091 F55A4.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00197092 C09D8.6 No description available WB:WBGene00197093 C08F8.11 No description available WB:WBGene00197094 K04D7.11 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197095 C56E6.15 No description available WB:WBGene00197096 C34E11.10 No description available WB:WBGene00197097 F13B9.9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sek-1; cep-1; and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00197098 R04E5.13 Is affected by daf-2 based on microarray studies. WB:WBGene00197099 ZC416.9 Is affected by set-2 and hlh-26 based on RNA-seq studies. WB:WBGene00197100 F28F5.11 Is affected by daf-2 based on microarray studies. WB:WBGene00197101 F46G11.11 No description available WB:WBGene00197102 C18A3.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00197103 C06G1.9 No description available WB:WBGene00197104 C35A5.14 Is affected by cep-1 and camt-1 based on RNA-seq studies. WB:WBGene00197105 C18H9.9 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197106 F28F5.12 No description available WB:WBGene00197107 F59A1.17 No description available WB:WBGene00197108 F26F12.10 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00197109 Y66A7AL.3 No description available WB:WBGene00197110 M03F8.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00197111 Y41D4B.28 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197112 Y105E8A.40 No description available WB:WBGene00197113 F22E12.7 No description available WB:WBGene00197114 C02C6.6 No description available WB:WBGene00197115 T14B1.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00197116 Y57G11C.1138 Enriched in neurons based on RNA-seq studies. WB:WBGene00197117 F45B8.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00197118 C34H3.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197119 F36D4.9 Is affected by dlc-1 and alh-4 based on RNA-seq studies. WB:WBGene00197120 F47G3.5 No description available WB:WBGene00197121 F14B6.8 No description available WB:WBGene00197122 K11D5.1 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00197123 F59G1.10 Enriched in neurons based on RNA-seq studies. Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00197124 T06H11.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00197125 T28F12.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00197126 C26E1.6 No description available WB:WBGene00197127 T05B11.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197128 T05A12.6 No description available WB:WBGene00197129 T01G1.5 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 and etr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197130 F11A1.11 No description available WB:WBGene00197131 C54D10.18 No description available WB:WBGene00197132 T21D9.4 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00197133 F14D1.2 Enriched in neurons based on RNA-seq studies. WB:WBGene00197134 K08B5.5 No description available WB:WBGene00197135 F40E10.9 No description available WB:WBGene00197136 C47G2.14 Is affected by Tunicamycin based on microarray studies. WB:WBGene00197137 R08B4.7 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by prg-1 and cep-1 based on RNA-seq studies. WB:WBGene00197138 F45H11.9 No description available WB:WBGene00197139 C08C3.8 No description available WB:WBGene00197140 F29D10.6 No description available WB:WBGene00197141 F07C3.13 No description available WB:WBGene00197142 C36B1.15 No description available WB:WBGene00197143 F21D9.10 No description available WB:WBGene00197144 F38H4.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00197145 W08F4.15 No description available WB:WBGene00197146 F41D9.10 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197147 C09D8.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1; dlc-1; and set-2 based on RNA-seq studies. WB:WBGene00197148 C48A7.7 No description available WB:WBGene00197149 C43F9.15 No description available WB:WBGene00197150 ZK265.13 Is affected by pmt-2 based on microarray studies. WB:WBGene00197151 K02B9.8 No description available WB:WBGene00197152 Y7A9D.63 No description available WB:WBGene00197153 T18D3.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197154 C17G1.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197155 F23H12.15 No description available WB:WBGene00197156 ZK1025.12 No description available WB:WBGene00197157 ZC64.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197158 T04F8.12 No description available WB:WBGene00197159 C34D1.8 No description available WB:WBGene00197160 K07A9.5 No description available WB:WBGene00197161 C24A8.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00197162 Y18H1A.16 Is affected by hpl-2 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197163 B0495.15 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; cep-1; and alg-1 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197164 T19D12.13 No description available WB:WBGene00197165 F47B8.16 No description available WB:WBGene00197166 C36F7.12 No description available WB:WBGene00197167 F48C1.13 Is affected by pmt-2 based on microarray studies. WB:WBGene00197168 ZC504.9 Is affected by chd-3; let-418; and met-2 based on RNA-seq studies. WB:WBGene00197169 E01H11.4 No description available WB:WBGene00197170 D1073.2 No description available WB:WBGene00197171 F56D12.10 Is affected by several genes including cep-1; egl-9; and ahr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197172 C03C10.12 No description available WB:WBGene00197173 F46G11.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00197174 F47B7.12 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00197175 C48A7.8 Is affected by eat-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00197176 Y39B6A.76 Enriched in neurons based on RNA-seq studies. WB:WBGene00197177 Y53C10A.18 Is affected by daf-2 based on microarray studies. WB:WBGene00197178 T08A9.16 Is affected by nhr-86 based on RNA-seq studies. WB:WBGene00197179 Y47D3B.15 Is affected by sodium arsenite based on RNA-seq studies. WB:WBGene00197180 C31H1.96 No description available WB:WBGene00197181 R02E12.11 Is affected by daf-2 based on microarray studies. WB:WBGene00197182 W10C8.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00197183 F55C10.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00197184 C30C11.8 No description available WB:WBGene00197185 Y70D2A.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00197186 C05G5.9 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 and lpd-3 based on RNA-seq studies. WB:WBGene00197187 Y56A3A.37 No description available WB:WBGene00197188 F18A11.8 Is affected by chd-3; let-418; and dlc-1 based on RNA-seq studies. WB:WBGene00197189 C06G1.10 Is affected by several genes including daf-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00197190 C14F11.13 No description available WB:WBGene00197191 T04A6.6 No description available WB:WBGene00197192 F10E9.14 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197193 C45E1.6 No description available WB:WBGene00197194 F41E7.11 No description available WB:WBGene00197195 ZK185.7 No description available WB:WBGene00197196 C04C11.10 No description available WB:WBGene00197197 Y73F8A.1165 Is affected by tdp-1 based on RNA-seq studies. WB:WBGene00197198 D1044.11 No description available WB:WBGene00197199 F31E8.11 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00197200 F59F3.9 No description available WB:WBGene00197201 M03F4.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00197202 F39D8.6 No description available WB:WBGene00197203 F52E4.10 No description available WB:WBGene00197204 B0034.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00197205 C23H4.10 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00197206 C15B12.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197207 K10D6.11 No description available WB:WBGene00197208 ZK1128.9 No description available WB:WBGene00197209 C34B4.11 Is affected by adr-1 and etr-1 based on RNA-seq studies. WB:WBGene00197210 F56D1.9 Is affected by tdp-1 and etr-1 based on RNA-seq studies. WB:WBGene00197211 C06E2.11 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00197212 F14F9.9 No description available WB:WBGene00197213 T09A5.17 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00197214 F38A3.4 No description available WB:WBGene00197215 F57A8.9 Is affected by several genes including skn-1; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by antimycin and cadmium based on RNA-seq studies. WB:WBGene00197216 ZC53.11 No description available WB:WBGene00197217 F59D12.11 Enriched in neurons based on RNA-seq studies. Is affected by ints-4 based on RNA-seq studies. WB:WBGene00197218 T04C12.19 No description available WB:WBGene00197219 F41E7.12 No description available WB:WBGene00197220 C54G7.9 No description available WB:WBGene00197221 F09F9.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197222 F29G9.10 No description available WB:WBGene00197223 F53B3.10 No description available WB:WBGene00197224 C54D1.10 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197225 T19C4.20 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00197226 F29G9.11 No description available WB:WBGene00197227 F31E8.12 Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq and microarray studies. WB:WBGene00197228 T06E8.3 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00197229 F52F12.11 No description available WB:WBGene00197230 F58G1.11 No description available WB:WBGene00197231 Y48B6A.18 Is affected by adr-1 and etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197232 Y54E10A.22 No description available WB:WBGene00197233 T05A6.10 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. WB:WBGene00197234 F55A12.13 Is affected by cep-1 and hlh-26 based on RNA-seq studies. WB:WBGene00197235 C41G11.11 No description available WB:WBGene00197236 K03H9.8 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00197237 F54D5.19 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197238 T19E7.24 No description available WB:WBGene00197239 R04F11.13 No description available WB:WBGene00197240 F22B3.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00197241 Y37E11C.3 No description available WB:WBGene00197242 K12G11.8 Is affected by alh-4 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00197243 C06G1.11 Is affected by daf-2 based on microarray studies. WB:WBGene00197244 C06E2.12 Is affected by pgrn-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197245 EGAP1.4 No description available WB:WBGene00197246 ZK809.11 No description available WB:WBGene00197247 B0495.16 Is affected by daf-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197248 K06C4.20 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00197249 C24G6.11 No description available WB:WBGene00197250 T02E9.15 Enriched in AVK based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00197251 T04C12.20 No description available WB:WBGene00197252 F41C6.10 No description available WB:WBGene00197253 Y13C8A.3 Is affected by uaf-1; srbc-48; and camt-1 based on RNA-seq studies. WB:WBGene00197254 R153.4 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197255 F57B7.7 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197256 F35C8.10 No description available WB:WBGene00197257 H21P03.6 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00197258 C54G4.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00197259 F11A6.8 Is affected by daf-12 and spr-5 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197260 F57B1.12 No description available WB:WBGene00197261 F10C1.14 Is affected by daf-2 based on microarray studies. WB:WBGene00197262 F19D8.9 No description available WB:WBGene00197263 K02A11.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00197264 ZC123.6 No description available WB:WBGene00197265 M195.6 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197266 K11G9.9 No description available WB:WBGene00197267 F25H8.10 No description available WB:WBGene00197268 F08F1.12 No description available WB:WBGene00197269 F59C12.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00197270 K02A4.4 No description available WB:WBGene00197271 W09G3.13 No description available WB:WBGene00197272 C18F3.7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00197273 C23H3.10 No description available WB:WBGene00197274 F20B10.7 No description available WB:WBGene00197275 K04D7.12 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00197276 Y54G2A.61 Enriched in neurons based on RNA-seq studies. WB:WBGene00197277 Y37E3.28 Is affected by prg-1 and cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197278 K03H4.3 Is affected by several genes including cep-1; let-418; and dlc-1 based on RNA-seq studies. WB:WBGene00197279 C01B7.10 Is affected by cep-1; dlc-1; and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00197280 ZC513.16 Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies. WB:WBGene00197281 Y41C4A.25 No description available WB:WBGene00197282 C44C11.3 No description available WB:WBGene00197283 R07G3.11 No description available WB:WBGene00197284 T24A11.5 Enriched in AFD and sensory neurons based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00197285 F48E3.12 No description available WB:WBGene00197286 C42D8.13 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00197287 Y104H12D.7 No description available WB:WBGene00197288 F13H6.10 No description available WB:WBGene00197289 T19B10.13 No description available WB:WBGene00197290 F21H7.17 No description available WB:WBGene00197291 F29C4.10 No description available WB:WBGene00197292 Y5H2B.8 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00197293 ZK1290.18 No description available WB:WBGene00197294 F53B7.9 No description available WB:WBGene00197295 K12H6.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00197296 C09B7.6 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; ints-4; and camt-1 based on RNA-seq studies. WB:WBGene00197297 R08C7.17 No description available WB:WBGene00197298 T23F11.8 No description available WB:WBGene00197299 C39E6.9 No description available WB:WBGene00197300 R08B4.8 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00197301 Y58A7A.9 No description available WB:WBGene00197302 C33F10.18 Enriched in AFD based on RNA-seq studies. Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197303 F26E4.16 Is affected by cep-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00197304 F43G6.12 No description available WB:WBGene00197305 C36F7.13 No description available WB:WBGene00197306 Y39A3CL.10 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197307 Y66A7AL.4 No description available WB:WBGene00197308 F55G1.18 No description available WB:WBGene00197309 K04H4.10 No description available WB:WBGene00197310 F26A10.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197311 C31G12.8 No description available WB:WBGene00197312 C47G2.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197313 F25B4.12 Is affected by dpy-21; daf-2; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00197314 F11D5.14 Is affected by adr-1; daf-2; and lpd-3 based on RNA-seq and microarray studies. WB:WBGene00197315 T13H10.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00197316 D1022.13 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00197317 T22F3.14 No description available WB:WBGene00197318 Y50D4C.8 Is affected by eat-2 based on microarray studies. WB:WBGene00197319 C32C4.12 No description available WB:WBGene00197320 F53B1.10 No description available WB:WBGene00197321 ZC504.10 No description available WB:WBGene00197322 T05G5.13 No description available WB:WBGene00197323 C04C3.11 No description available WB:WBGene00197324 F16A11.6 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00197325 T24A6.23 Is affected by daf-2 based on microarray studies. WB:WBGene00197326 F25G6.16 Enriched in germ line based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00197327 F48C5.7 No description available WB:WBGene00197328 F55C12.11 No description available WB:WBGene00197329 K06G5.6 No description available WB:WBGene00197330 W02H5.15 No description available WB:WBGene00197331 M01G4.5 No description available WB:WBGene00197332 F45B8.11 No description available WB:WBGene00197333 cTel3X.2 No description available WB:WBGene00197334 T25F10.8 No description available WB:WBGene00197335 C05D2.14 No description available WB:WBGene00197336 H20J04.10 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197337 Y67D11A.2 No description available WB:WBGene00197338 F39H12.5 No description available WB:WBGene00197339 Y51A2D.28 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00197340 ZK867.10 No description available WB:WBGene00197341 R06C1.8 No description available WB:WBGene00197342 F37H8.8 No description available WB:WBGene00197343 W02B8.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197344 F11D5.15 No description available WB:WBGene00197345 Y50D4A.7 No description available WB:WBGene00197346 F02D10.12 No description available WB:WBGene00197347 F11E6.20 Is affected by dlc-1 and nfki-1 based on RNA-seq studies. WB:WBGene00197348 T25B9.13 No description available WB:WBGene00197349 C05E11.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197350 C18E9.13 No description available WB:WBGene00197351 F54F2.10 No description available WB:WBGene00197352 F07C4.16 No description available WB:WBGene00197353 T26E3.14 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00197354 T07C12.17 No description available WB:WBGene00197355 F52F10.7 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00197356 F01G12.11 No description available WB:WBGene00197357 Y69H2.19 No description available WB:WBGene00197358 K10C9.11 No description available WB:WBGene00197359 C16E9.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197360 F46H6.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197361 K12C11.8 No description available WB:WBGene00197362 C23H4.11 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00197363 W02F12.11 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00197364 C36F7.14 No description available WB:WBGene00197365 T05C12.13 No description available WB:WBGene00197366 F22A3.12 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00197367 W05E10.12 No description available WB:WBGene00197368 T05B4.16 No description available WB:WBGene00197369 F48G7.14 No description available WB:WBGene00197370 Y37E11AL.14 No description available WB:WBGene00197371 Y76A2B.8 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197372 K08A8.11 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00197373 K03A1.9 No description available WB:WBGene00197374 K04H4.11 Is affected by hmg-3; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00197375 F13H6.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00197376 F28E10.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00197377 C05E11.13 No description available WB:WBGene00197378 T22A3.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197379 F16F9.8 No description available WB:WBGene00197380 F08F1.13 No description available WB:WBGene00197381 C07A12.10 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00197382 K08B12.8 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00197383 F55F1.7 No description available WB:WBGene00197384 C18C4.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00197385 F18C5.13 Is affected by hmg-3 and etr-1 based on RNA-seq studies. WB:WBGene00197386 Y105C5A.1276 No description available WB:WBGene00197387 F35E8.18 Is affected by daf-2 based on microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00197388 F54E4.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00197389 F38B6.11 No description available WB:WBGene00197390 T21F2.2 Enriched in AFD and neurons based on RNA-seq studies. Is affected by cep-1 and set-2 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197391 K12H4.10 No description available WB:WBGene00197392 K01A2.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00197393 C06B8.14 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197394 H14E04.6 No description available WB:WBGene00197395 Y57A10A.40 No description available WB:WBGene00197396 F38B2.7 No description available WB:WBGene00197397 Y67D8C.14 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197398 F29F11.9 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00197399 C49H3.14 No description available WB:WBGene00197400 B0336.14 No description available WB:WBGene00197401 K08E3.13 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00197402 T07F12.7 No description available WB:WBGene00197403 T14F9.12 No description available WB:WBGene00197404 K03H1.18 No description available WB:WBGene00197405 K02F6.10 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00197406 K02A4.5 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197407 F40B5.5 Is affected by cep-1 and spr-5 based on RNA-seq studies. WB:WBGene00197408 F38E11.21 Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197409 K01B6.6 No description available WB:WBGene00197410 F10C1.15 No description available WB:WBGene00197411 W03G9.11 No description available WB:WBGene00197412 T24F1.9 No description available WB:WBGene00197413 C02B4.6 No description available WB:WBGene00197414 C43C3.7 No description available WB:WBGene00197415 F35A5.10 Is affected by daf-2 based on microarray studies. WB:WBGene00197416 F16F9.9 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197417 H28G03.7 No description available WB:WBGene00197418 F01E11.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197419 C54G7.10 No description available WB:WBGene00197420 T22B11.7 No description available WB:WBGene00197421 C54D2.10 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and hmg-3 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197422 F08B12.7 Is affected by pmt-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197423 F40F8.14 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by Cry5B based on microarray studies. WB:WBGene00197424 K11D9.6 Is affected by adr-1; mrps-5; and etr-1 based on RNA-seq studies. WB:WBGene00197425 R11F4.5 No description available WB:WBGene00197426 K08F8.8 Is affected by cep-1; daf-2; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00197427 Y42H9B.5 No description available WB:WBGene00197428 K01B6.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00197429 W03G11.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00197430 T09A5.18 No description available WB:WBGene00197431 Y67D8C.15 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00197432 T21G5.7 No description available WB:WBGene00197433 F26H11.9 Is affected by daf-2; eat-2; and pmt-2 based on microarray studies. WB:WBGene00197434 F26A10.12 No description available WB:WBGene00197435 C11G6.5 No description available WB:WBGene00197436 Y49G5B.2 Is affected by cep-1 and ifo-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197437 K09E2.6 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00197438 T05A8.9 No description available WB:WBGene00197439 C33D12.11 No description available WB:WBGene00197440 F14F7.6 No description available WB:WBGene00197441 T08B2.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197442 B0491.9 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197443 F20D1.14 No description available WB:WBGene00197444 K05G3.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00197445 Y17G9A.86 No description available WB:WBGene00197446 C48D5.6 No description available WB:WBGene00197447 T21E12.7 No description available WB:WBGene00197448 ZK622.7 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197449 F13D11.11 Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197450 ZK84.10 No description available WB:WBGene00197451 C26G2.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00197452 C25F6.13 Is affected by lpd-3 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197453 H35N09.3 No description available WB:WBGene00197454 T04H1.11 Is affected by let-418 based on RNA-seq studies. WB:WBGene00197455 F45B8.12 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00197456 C39E9.16 No description available WB:WBGene00197457 T10B11.10 No description available WB:WBGene00197458 C16E9.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197459 F28B4.5 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00197460 C31E10.10 Is affected by daf-2 based on microarray studies. WB:WBGene00197461 T04C10.8 No description available WB:WBGene00197462 C02B4.7 No description available WB:WBGene00197463 F32A6.8 Enriched in neurons based on RNA-seq studies. Is affected by ifo-1 and camt-1 based on microarray and RNA-seq studies. WB:WBGene00197464 F15A8.8 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00197465 C25F6.14 Is affected by daf-12; daf-16; and dpy-21 based on RNA-seq studies. WB:WBGene00197466 F52B10.12 No description available WB:WBGene00197467 ZK836.8 Is affected by cep-1 and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00197468 T02E9.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197469 H16O14.77 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197470 F29B9.14 No description available WB:WBGene00197471 F56E3.10 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197472 F28E10.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00197473 C05A9.4 Is affected by ifo-1 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197474 C41A3.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197475 W01C8.11 Is affected by cep-1 and alg-1 based on RNA-seq studies. WB:WBGene00197476 C41A3.8 Is affected by eat-2 based on microarray studies. WB:WBGene00197477 H05O09.3 Is affected by set-2 and etr-1 based on RNA-seq studies. WB:WBGene00197478 T13B5.10 No description available WB:WBGene00197479 F18G5.9 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00197480 ZK1193.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197481 F38A6.6 Is affected by cep-1; mrps-5; and etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00197482 C07A12.11 No description available WB:WBGene00197483 F27B10.3 No description available WB:WBGene00197484 C03A3.4 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 and mrps-5 based on RNA-seq studies. WB:WBGene00197485 C55C3.72 Is affected by daf-16 based on RNA-seq studies. WB:WBGene00197486 R151.15 Is affected by eat-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00197487 F13C5.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00197488 F41C6.11 Is affected by pmt-2 and met-2 based on microarray and RNA-seq studies. WB:WBGene00197489 C30B5.12 No description available WB:WBGene00197490 M02G9.5 No description available WB:WBGene00197491 R04F11.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00197492 T06H11.10 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00197493 T28B11.11 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; dlc-1; and pmt-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00197494 R09D1.16 No description available WB:WBGene00197495 R11B5.5 No description available WB:WBGene00197496 F35D2.10 Is affected by daf-2 based on microarray studies. WB:WBGene00197497 T24D5.8 No description available WB:WBGene00197498 R11B5.6 Enriched in neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00197499 F08C6.12 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00197500 F08G2.14 No description available WB:WBGene00197501 T21C9.15 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00197502 T14B4.13 No description available WB:WBGene00197503 C45E1.7 Is affected by lpd-3 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197504 F23F12.15 Is affected by daf-2 based on microarray studies. WB:WBGene00197505 C01F4.6 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00197506 F23F12.16 No description available WB:WBGene00197507 R08E3.7 No description available WB:WBGene00197508 ZC334.14 No description available WB:WBGene00197509 R02E4.4 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197510 C18B12.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by daf-2 and alh-4 based on microarray and RNA-seq studies. WB:WBGene00197511 ZK470.9 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 and etr-1 based on RNA-seq studies. WB:WBGene00197512 Y116F11A.7 No description available WB:WBGene00197513 F22F1.5 Is affected by daf-2 based on microarray studies. WB:WBGene00197514 B0285.14 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197515 C49F8.9 No description available WB:WBGene00197516 T04C12.21 No description available WB:WBGene00197517 R03G5.8 Is affected by sek-1 based on RNA-seq studies. WB:WBGene00197518 F57G12.5 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00197519 Y105E8A.41 No description available WB:WBGene00197520 C05C8.10 Enriched in head mesodermal cell and neurons based on RNA-seq studies. Is affected by several genes including set-2; dlc-1; and etr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00197521 ZC404.17 No description available WB:WBGene00197522 T21B6.10 Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00197523 F58H1.15 Is affected by dlc-1 and etr-1 based on RNA-seq studies. WB:WBGene00197524 D2023.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00197525 T10H9.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00197526 F32B5.11 No description available WB:WBGene00197527 F44D12.17 No description available WB:WBGene00197528 F44C4.10 No description available WB:WBGene00197529 C29E6.12 No description available WB:WBGene00197530 T12B5.16 No description available WB:WBGene00197531 B0198.5 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00197532 F09D5.3 Enriched in sensory neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00197533 F42G2.9 No description available WB:WBGene00197534 F38H4.13 Is affected by daf-2; eat-2; and ints-4 based on microarray and RNA-seq studies. WB:WBGene00197535 R13.7 No description available WB:WBGene00197536 M01G5.9 No description available WB:WBGene00197537 T08B1.8 No description available WB:WBGene00197538 Y26D4A.23 No description available WB:WBGene00197539 C07H6.13 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00197540 T08H4.7 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00197541 C07G1.10 No description available WB:WBGene00197542 W01A11.11 No description available WB:WBGene00197543 F57C7.9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00197544 Y7A5A.15 No description available WB:WBGene00197545 Y53F4B.55 No description available WB:WBGene00197546 F39B3.6 No description available WB:WBGene00197547 Y39B6A.77 Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197548 T10B10.11 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00197549 T09B4.15 No description available WB:WBGene00197550 T24B8.12 Is affected by adr-1 based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00197551 T22D1.20 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197552 Y49F6B.15 Is affected by several genes including daf-2; eat-2; and unc-30 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197553 F45E1.10 Is affected by eat-2 based on microarray studies. WB:WBGene00197554 T14G12.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197555 Y67D8A.8 Enriched in AFD and ASER based on RNA-seq studies. Is affected by several genes including unc-30; dlc-1; and hlh-26 based on RNA-seq studies. WB:WBGene00197556 C42D8.14 No description available WB:WBGene00197557 F25H10.4 No description available WB:WBGene00197558 Y38H6A.7 No description available WB:WBGene00197559 C17D12.12 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197560 K08A2.12 No description available WB:WBGene00197561 C33F10.19 No description available WB:WBGene00197562 T10D4.16 No description available WB:WBGene00197563 B0403.9 No description available WB:WBGene00197564 F52D10.8 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00197565 F39B2.12 Is affected by set-2 based on RNA-seq studies. WB:WBGene00197566 E03E2.2 No description available WB:WBGene00197567 C32C4.13 No description available WB:WBGene00197568 F49E11.12 No description available WB:WBGene00197569 F46G11.13 No description available WB:WBGene00197570 F33D11.15 No description available WB:WBGene00197571 C41G11.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00197572 F52B10.13 Is affected by ifo-1 based on microarray studies. WB:WBGene00197573 F14B8.11 No description available WB:WBGene00197574 C04C11.11 Is affected by daf-2 based on microarray studies. WB:WBGene00197575 C30C11.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00197576 C01C10.5 Is affected by daf-2 based on microarray studies. WB:WBGene00197577 W08F4.16 No description available WB:WBGene00197578 F13D11.12 Is affected by mrps-5 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197579 F44A2.9 No description available WB:WBGene00197580 F19B6.6 No description available WB:WBGene00197581 T28B4.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00197582 T03G11.17 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00197583 T26H10.4 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197584 Y40C5A.17 No description available WB:WBGene00197585 T08G11.8 Enriched in AFD based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197586 ZC64.12 No description available WB:WBGene00197587 F38B7.14 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00197588 T08G2.5 No description available WB:WBGene00197589 C39D10.14 Is affected by daf-2 based on microarray studies. WB:WBGene00197590 F30H5.6 No description available WB:WBGene00197591 K08B12.9 Is affected by dlc-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197592 F52D10.9 Is affected by pmt-2 based on microarray studies. WB:WBGene00197593 F18F11.6 No description available WB:WBGene00197594 T24B8.13 No description available WB:WBGene00197595 R12E2.18 Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00197596 C25A11.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197597 M163.17 Is affected by cep-1 and ints-4 based on RNA-seq studies. WB:WBGene00197598 F56A11.9 Is affected by chd-3; let-418; and dlc-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197599 F52B10.14 Is affected by daf-2 based on microarray studies. WB:WBGene00197600 C14F5.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197601 T26H10.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00197602 F28F8.12 Is affected by daf-2 based on microarray studies. WB:WBGene00197603 T19C4.21 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197604 K01G5.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00197605 H13J03.1 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197606 F35B3.8 No description available WB:WBGene00197607 F47F2.5 No description available WB:WBGene00197608 T02E9.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00197609 ZC21.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197610 Y38H8A.11 No description available WB:WBGene00197611 C39E9.17 No description available WB:WBGene00197612 Y53F4B.56 No description available WB:WBGene00197613 F49D11.13 Is affected by daf-2 based on microarray studies. WB:WBGene00197614 ZC506.6 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00197615 C25F6.15 Is affected by alg-1 and adr-1 based on RNA-seq studies. WB:WBGene00197616 C29A12.11 No description available WB:WBGene00197617 C06E7.90 Is affected by daf-2 based on microarray studies. WB:WBGene00197618 F47G4.12 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197619 Y110A2AL.18 Enriched in AFD based on RNA-seq studies. WB:WBGene00197620 Y75B8A.49 Is affected by lem-2; emr-1; and hmg-3 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00197621 F45F2.14 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197622 CD4.14 Is affected by alg-1; daf-2; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00197623 B0240.5 No description available WB:WBGene00197624 Y55F3C.15 No description available WB:WBGene00197625 T27E4.16 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and ints-2 based on RNA-seq studies. WB:WBGene00197626 ZK381.43 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197627 Y37F4.11 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00197628 K08E5.11 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00197629 F58F12.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197630 AH10.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00197631 F43G6.13 No description available WB:WBGene00197632 T23E7.8 No description available WB:WBGene00197633 C56G2.18 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00197634 C40C9.12 Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197635 C31H2.7 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00197636 Y67D8C.16 Enriched in sensory neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00197637 R13F6.13 Is affected by dlc-1 based on RNA-seq studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00197638 F43D2.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00197639 Y39A1B.6 No description available WB:WBGene00197640 F57B1.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00197641 T03F7.12 No description available WB:WBGene00197642 C16E9.15 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197643 F13H6.12 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197644 H30A04.3 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197645 C39E6.10 No description available WB:WBGene00197646 ZK795.7 No description available WB:WBGene00197647 K03C7.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197648 ZK20.8 No description available WB:WBGene00197649 K03C7.8 No description available WB:WBGene00197650 Y54F10AM.12 No description available WB:WBGene00197651 R03A10.10 Is affected by daf-2 based on microarray studies. WB:WBGene00197652 C05B5.13 No description available WB:WBGene00197653 R186.11 No description available WB:WBGene00197654 T16G1.14 Is affected by eat-2 based on microarray studies. WB:WBGene00197655 F45E1.11 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197656 F09D5.4 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00197657 F11A5.20 No description available WB:WBGene00197658 T01C1.9 Is affected by elli-1 based on microarray studies. WB:WBGene00197659 F43C11.14 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197660 C27A2.11 Is affected by hmg-3 and adr-1 based on RNA-seq studies. WB:WBGene00197661 R12B2.9 Is affected by cep-1; met-2; and fzo-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197662 B0403.10 Enriched in neurons based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00197663 F13H6.13 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; cep-1; and adr-1 based on RNA-seq and microarray studies. Is affected by glycine; silicon dioxide nanoparticle; and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00197664 Y51A2D.29 Enriched in neurons based on RNA-seq studies. Is affected by ikb-1 and nfki-1 based on RNA-seq studies. WB:WBGene00197665 C48G7.4 Is affected by pmt-2 based on microarray studies. WB:WBGene00197666 C05D2.15 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197667 R160.8 Enriched in AVK based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197668 F46H5.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197669 F56F3.10 No description available WB:WBGene00197670 C54C6.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00197671 F46C8.12 Is affected by daf-2 based on microarray studies. WB:WBGene00197672 C48A7.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197673 ZK973.17 Is affected by sams-3 based on RNA-seq studies. WB:WBGene00197674 F58H1.16 Is affected by cep-1; adr-1; and daf-12 based on RNA-seq studies. Is affected by Tunicamycin; Cry5B; and Oligosaccharides based on microarray studies. WB:WBGene00197675 ZK84.11 No description available WB:WBGene00197676 Y59A8B.29 No description available WB:WBGene00197677 F14F3.9 No description available WB:WBGene00197678 R01E6.11 No description available WB:WBGene00197679 F13H6.14 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00197680 Y76F7A.3 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00197681 Y51A2B.12 No description available WB:WBGene00197682 R52.11 No description available WB:WBGene00197683 ZK816.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197684 F59B2.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197685 Y53C12B.8 No description available WB:WBGene00197686 B0034.10 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197687 C54H2.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00197688 ZK836.9 Is affected by ifo-1 based on microarray studies. WB:WBGene00197689 F08G5.13 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00197690 C08G9.5 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00197691 K08F8.9 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-3; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00197692 Y22D7AR.18 No description available WB:WBGene00197693 F36D1.16 No description available WB:WBGene00197694 D2089.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00197695 C18F3.8 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197696 C49A1.13 No description available WB:WBGene00197697 B0432.19 No description available WB:WBGene00197698 C05D12.9 No description available WB:WBGene00197699 F53B7.10 No description available WB:WBGene00197700 K09B11.20 Is affected by mett-10 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00197701 F44E5.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00197702 C27F2.11 No description available WB:WBGene00197703 F53B2.14 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00197704 B0379.11 No description available WB:WBGene00197705 R01E6.12 No description available WB:WBGene00197706 ZK470.10 No description available WB:WBGene00197707 F20D1.15 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00197708 K12H4.11 Enriched in neurons based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00197709 W09B12.3 No description available WB:WBGene00197710 C14F11.14 Is affected by several genes including cep-1; adr-1; and sftb-1 based on RNA-seq studies. WB:WBGene00197711 Y32F6B.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00197712 F48A9.4 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00197713 Y48G8AR.4 No description available WB:WBGene00197714 Y54E10BL.8 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00197715 B0024.17 No description available WB:WBGene00197716 H15M21.1 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00197717 T01B6.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197718 F25G6.17 No description available WB:WBGene00197719 Y42G9A.8 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00197720 ZC504.11 No description available WB:WBGene00197721 C45G7.8 No description available WB:WBGene00197722 F43D9.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00197723 Y69A2AR.39 No description available WB:WBGene00197724 F36H1.15 Is affected by lem-2 and emr-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00197725 ZK1025.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00197726 C44B7.16 No description available WB:WBGene00197727 F49H12.10 No description available WB:WBGene00197728 C52B11.7 No description available WB:WBGene00197729 R08B4.9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. WB:WBGene00197730 C13G3.6 No description available WB:WBGene00197731 F46F3.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197732 T02E9.18 Is affected by cep-1; daf-2; and camt-1 based on RNA-seq and microarray studies. WB:WBGene00197733 T25C12.5 Enriched in head mesodermal cell; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by iron oxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00197734 W07G1.12 No description available WB:WBGene00197735 F36D4.10 No description available WB:WBGene00197736 B0207.14 No description available WB:WBGene00197737 F38E9.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00197738 F43G9.15 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00197739 F29F11.10 No description available WB:WBGene00197740 T21H3.7 No description available WB:WBGene00197741 C54A12.6 No description available WB:WBGene00197742 F41D9.11 Is affected by several genes including cep-1; set-2; and hda-2 based on RNA-seq studies. WB:WBGene00197743 F11C1.13 Is affected by eat-2 based on microarray studies. WB:WBGene00197744 F46C8.13 No description available WB:WBGene00197745 C47E12.16 No description available WB:WBGene00197746 ZK84.12 No description available WB:WBGene00197747 Y39H10A.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197748 T05A1.16 Is affected by daf-2 based on microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00197749 F35H10.15 No description available WB:WBGene00197750 ZK377.5 Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00197751 ZK945.11 No description available WB:WBGene00197752 F46F3.9 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00197753 F58H1.17 No description available WB:WBGene00197754 Y92C3A.6 No description available WB:WBGene00197755 ZK899.10 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00197756 ZC250.8 No description available WB:WBGene00197757 H36N01.1 No description available WB:WBGene00197758 C36F7.15 Enriched in neurons based on RNA-seq studies. Is affected by let-418 based on RNA-seq studies. WB:WBGene00197759 F56E3.11 No description available WB:WBGene00197760 M163.18 No description available WB:WBGene00197761 C18A11.10 Is affected by rbr-2 based on RNA-seq studies. WB:WBGene00197762 K09F5.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00197763 F44E8.43 Is affected by several genes including daf-2; eat-2; and pmt-2 based on microarray and RNA-seq studies. WB:WBGene00197764 F49E2.7 No description available WB:WBGene00197765 C01B7.11 No description available WB:WBGene00197766 C24A3.11 No description available WB:WBGene00197767 B0285.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197768 W03G11.12 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00197769 T28B11.12 Is affected by several genes including cep-1; let-418; and dlc-1 based on RNA-seq studies. WB:WBGene00197770 F27C8.12 No description available WB:WBGene00197771 F09A5.12 No description available WB:WBGene00197772 F22D6.18 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197773 T27A10.8 Is affected by several genes including lem-2; ahr-1; and emr-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Ethanol; sodium arsenite; and bisphenol A based on RNA-seq studies. WB:WBGene00197774 T10H4.18 No description available WB:WBGene00197775 F26F12.11 Is affected by pgrn-1 and dlc-1 based on RNA-seq studies. WB:WBGene00197776 F52F12.12 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00197777 F13C5.9 No description available WB:WBGene00197778 K06A1.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00197779 T27E4.17 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00197780 F48B9.10 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00197781 T04D3.10 Is affected by daf-2 based on microarray studies. WB:WBGene00197782 K09E9.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00197783 R07B1.20 Is affected by daf-2 based on microarray studies. WB:WBGene00197784 K08A8.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197785 ZK1151.4 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00197786 K02G10.10 No description available WB:WBGene00197787 ZC53.12 No description available WB:WBGene00197788 ZC581.12 No description available WB:WBGene00197789 Y6B3B.13 No description available WB:WBGene00197790 C07A4.6 No description available WB:WBGene00197791 F54C9.16 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00197792 H03A11.7 No description available WB:WBGene00197793 T22B7.11 No description available WB:WBGene00197794 M04D5.5 No description available WB:WBGene00197795 F43D2.10 Is affected by pmt-2 based on microarray studies. WB:WBGene00197796 B0001.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197797 K08H10.16 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00197798 T05A6.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197799 B0454.17 No description available WB:WBGene00197800 H01A20.3 No description available WB:WBGene00197801 F58H1.18 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00197802 T19F4.3 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00197803 K07C10.6 Is affected by rsr-2 and ints-5 based on RNA-seq studies. WB:WBGene00197804 F27D9.11 No description available WB:WBGene00197805 C43G2.27 No description available WB:WBGene00197806 T22E5.12 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00197807 F52E4.11 No description available WB:WBGene00197808 K12G11.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197809 B0334.18 Is affected by daf-2 based on microarray studies. WB:WBGene00197810 Y17G9A.87 Is affected by set-2 based on RNA-seq studies. WB:WBGene00197811 ZK180.10 Enriched in neurons based on RNA-seq studies. Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00197812 C06E8.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197813 T13H10.9 No description available WB:WBGene00197814 F54A3.9 No description available WB:WBGene00197815 F56A11.10 No description available WB:WBGene00197816 T22E5.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00197817 C07B5.9 No description available WB:WBGene00197818 ZK381.44 Enriched in neurons based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00197819 T01B7.11 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00197820 C15A7.6 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00197821 T01B10.10 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00197822 H22K11.8 No description available WB:WBGene00197823 Y52B11B.2 No description available WB:WBGene00197824 Y73F8A.1166 No description available WB:WBGene00197825 C54G4.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00197826 C53C9.4 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. WB:WBGene00197827 R04F11.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00197828 C02B4.8 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pmt-2 based on microarray and RNA-seq studies. Is affected by Ethanol and multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00197829 C05C9.8 No description available WB:WBGene00197830 C13G3.7 Is affected by daf-2 based on microarray studies. WB:WBGene00197831 M01G5.10 No description available WB:WBGene00197832 F26A10.13 No description available WB:WBGene00197833 C38C5.2 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00197834 T16G1.15 Is affected by ifo-1 based on microarray studies. WB:WBGene00197835 F25B5.10 No description available WB:WBGene00197836 C29A12.12 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00197837 K11C4.9 Is affected by Cry5B based on microarray studies. WB:WBGene00197838 C02D4.6 No description available WB:WBGene00197839 F14D12.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00197840 F58G11.8 Is affected by dpy-21 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00197841 K03B8.17 No description available WB:WBGene00197842 Y54G2A.62 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197843 ZK1010.11 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00197844 F54E4.11 No description available WB:WBGene00197845 F55C12.12 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197846 W03G11.13 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00197847 K12G11.10 No description available WB:WBGene00197848 F52B10.15 Is affected by ifo-1 based on microarray studies. WB:WBGene00197849 F18E2.11 No description available WB:WBGene00197850 W06B3.4 Is affected by pgrn-1 and cep-1 based on RNA-seq studies. WB:WBGene00197851 F49E7.3 No description available WB:WBGene00197852 Y64G10A.354 No description available WB:WBGene00197853 C53C11.7 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00197854 W01H2.6 No description available WB:WBGene00197855 Y50E8A.20 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197856 F53F4.22 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197857 C53D6.19 No description available WB:WBGene00197858 F47G3.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197859 C09B8.13 No description available WB:WBGene00197860 Y38F2AR.17 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197861 F10D7.7 Is affected by daf-2 based on microarray studies. WB:WBGene00197862 T10E10.10 No description available WB:WBGene00197863 F54G2.3 No description available WB:WBGene00197864 C17E4.16 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197865 D1046.10 No description available WB:WBGene00197866 F26H11.10 Is affected by daf-2 based on microarray studies. WB:WBGene00197867 Y48B6A.19 Is affected by daf-2 and klf-1 based on microarray and RNA-seq studies. WB:WBGene00197868 T19A5.7 No description available WB:WBGene00197869 D1054.20 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00197870 Y43F4A.5 Is affected by daf-2 and dpy-21 based on RNA-seq studies. WB:WBGene00197871 D1081.14 No description available WB:WBGene00197872 Y54E10A.23 No description available WB:WBGene00197873 F55A4.12 Is affected by daf-2 based on microarray studies. WB:WBGene00197874 C27F2.12 No description available WB:WBGene00197875 T19F4.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00197876 F31F6.10 No description available WB:WBGene00197877 Y66A7AL.5 No description available WB:WBGene00197878 F22E10.9 No description available WB:WBGene00197879 ZK287.11 No description available WB:WBGene00197880 C54G7.11 Is affected by hmg-3 and hmg-4 based on RNA-seq studies. WB:WBGene00197881 C31G12.9 No description available WB:WBGene00197882 F12F3.5 Enriched in AFD and sensory neurons based on RNA-seq studies. Is affected by several genes including set-2; dlc-1; and hda-2 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197883 F31E8.13 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00197884 F01F1.16 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00197885 F43D2.11 No description available WB:WBGene00197886 C13B4.5 No description available WB:WBGene00197887 C30F2.6 Is affected by sodium arsenite based on RNA-seq studies. WB:WBGene00197888 F16D3.8 Enriched in AFD and neurons based on RNA-seq studies. Is affected by dlc-1 and mrps-5 based on RNA-seq studies. WB:WBGene00197889 R02D5.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00197890 F47C8.2 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197891 C29F3.9 Is affected by cep-1; daf-2; and nhr-86 based on RNA-seq and microarray studies. WB:WBGene00197892 Y39B6A.78 No description available WB:WBGene00197893 F25C8.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197894 F52E10.9 Is affected by daf-2 based on microarray studies. WB:WBGene00197895 C14B9.13 Is affected by hmg-3; daf-2; and set-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00197896 Y15E3A.8 Is affected by dpy-21 and nfki-1 based on RNA-seq studies. WB:WBGene00197897 F58A4.19 No description available WB:WBGene00197898 W09D6.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197899 ZK682.9 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00197900 M01A10.7 No description available WB:WBGene00197901 H01G02.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197902 R53.10 No description available WB:WBGene00197903 T28B4.10 Enriched in AVK and neurons based on RNA-seq studies. WB:WBGene00197904 T21H8.7 No description available WB:WBGene00197905 F26F12.12 No description available WB:WBGene00197906 T04C9.7 Enriched in AVK and neurons based on RNA-seq studies. Is affected by cep-1; adr-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197907 Y75B7AL.6 No description available WB:WBGene00197908 B0303.17 No description available WB:WBGene00197909 F18A11.9 No description available WB:WBGene00197910 F01D5.13 No description available WB:WBGene00197911 F40E10.10 No description available WB:WBGene00197912 C25F6.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197913 R90.7 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197914 C14C11.10 No description available WB:WBGene00197915 C17H12.30 Is affected by let-418 based on RNA-seq studies. WB:WBGene00197916 K01A11.6 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00197917 C06E1.14 No description available WB:WBGene00197918 B0344.3 Is affected by nhr-86 based on RNA-seq studies. WB:WBGene00197919 C24E9.2 No description available WB:WBGene00197920 K03H6.10 No description available WB:WBGene00197921 C14F11.15 No description available WB:WBGene00197922 F43E12.3 No description available WB:WBGene00197923 F57G12.6 Is affected by alg-1 based on RNA-seq studies. WB:WBGene00197924 E04D5.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00197925 F31E3.9 Enriched in AFD based on RNA-seq studies. WB:WBGene00197926 K03B8.18 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00197927 C04D8.3 Is affected by cep-1; dlc-1; and set-2 based on RNA-seq studies. WB:WBGene00197928 F29F11.11 No description available WB:WBGene00197929 Y9C9A.109 No description available WB:WBGene00197930 T06H11.11 Enriched in neurons based on RNA-seq studies. Is affected by several genes including met-2; hpl-2; and spr-5 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and procyanidin based on RNA-seq and microarray studies. WB:WBGene00197931 K10B4.9 No description available WB:WBGene00197932 K08A2.13 No description available WB:WBGene00197933 F08F1.14 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00197934 ZK867.11 Is affected by cep-1; camt-1; and etr-1 based on RNA-seq studies. WB:WBGene00197935 T04C10.9 No description available WB:WBGene00197936 Y73B6BL.275 Is affected by several genes including tdp-1; rpl-5; and hmg-4 based on RNA-seq studies. WB:WBGene00197937 B0250.16 No description available WB:WBGene00197938 C35A11.7 No description available WB:WBGene00197939 C06E4.15 No description available WB:WBGene00197940 F40E3.8 Is affected by hlh-26 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197941 ZC328.7 No description available WB:WBGene00197942 T25D3.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197943 C34D1.9 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00197944 F26D11.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00197945 C53C7.6 No description available WB:WBGene00197946 ZK622.8 No description available WB:WBGene00197947 Y51H7C.22 No description available WB:WBGene00197948 T03G11.18 No description available WB:WBGene00197949 T25B6.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00197950 K02B12.11 Is affected by daf-2 based on microarray studies. WB:WBGene00197951 Y43E12A.5 No description available WB:WBGene00197952 C18D1.14 Enriched in sensory neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00197953 T06F4.8 No description available WB:WBGene00197954 B0393.13 No description available WB:WBGene00197955 VT23B5.1 Is affected by several genes including daf-2; set-2; and lin-22 based on microarray and RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00197956 C35C5.16 Is affected by daf-2; set-2; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00197957 Y106G6A.9 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00197958 B0034.11 No description available WB:WBGene00197959 C46G7.107 No description available WB:WBGene00197960 C06E2.13 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00197961 Y65B4BL.11 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00197962 Y43F4A.6 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and pmt-2 based on microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00197963 F41E7.13 Is affected by eat-2 based on microarray studies. WB:WBGene00197964 F10E9.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00197965 C30F12.8 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00197966 B0393.14 Is affected by cep-1; alg-1; and set-2 based on RNA-seq studies. WB:WBGene00197967 C07A4.7 No description available WB:WBGene00197968 ZK1290.19 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00197969 Y70D2A.6 Is affected by daf-2 based on microarray studies. WB:WBGene00197970 C11G10.6 No description available WB:WBGene00197971 T06D10.6 No description available WB:WBGene00197972 F35C11.10 No description available WB:WBGene00197973 C05G5.10 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and camt-1 based on microarray and RNA-seq studies. WB:WBGene00197974 C44C11.4 No description available WB:WBGene00197975 C06G1.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00197976 F56D1.10 Enriched in AFD based on RNA-seq studies. Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00197977 F47G3.7 Is affected by pmt-2 based on microarray studies. WB:WBGene00197978 ZC123.7 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00197979 K05F1.12 Is affected by Tunicamycin based on microarray studies. WB:WBGene00197980 K01A2.14 No description available WB:WBGene00197981 ZC64.13 No description available WB:WBGene00197982 B0410.4 No description available WB:WBGene00197983 F18A11.10 Is affected by dlc-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00197984 F43D9.10 No description available WB:WBGene00197985 K04A8.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00197986 F46H6.9 No description available WB:WBGene00197987 F45E4.17 No description available WB:WBGene00197988 Y73F8A.1167 No description available WB:WBGene00197989 R07D5.5 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00197990 T06F4.9 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00197991 T04C12.22 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00197992 C14F11.16 No description available WB:WBGene00197993 F54A5.4 No description available WB:WBGene00197994 C34E11.11 No description available WB:WBGene00197995 F11D5.16 Is affected by cep-1; let-418; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00197996 C45E1.8 No description available WB:WBGene00197997 H01G02.9 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00197998 T07D1.10 Is affected by daf-2 based on microarray studies. WB:WBGene00197999 T01C2.4 No description available WB:WBGene00198000 K08B5.6 Is affected by Tunicamycin based on microarray studies. WB:WBGene00198001 Y54E10A.24 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; unc-30; and dlc-1 based on RNA-seq studies. WB:WBGene00198002 F14F11.3 Enriched in neurons based on RNA-seq studies. WB:WBGene00198003 C54G7.12 No description available WB:WBGene00198004 K02A4.6 No description available WB:WBGene00198005 C26G2.5 No description available WB:WBGene00198006 R160.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198007 C34B4.12 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00198008 M60.9 Is affected by daf-2; pmt-2; and etr-1 based on microarray and RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198009 C50D2.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198010 Y17G7A.3 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00198011 T20F10.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198012 Y54G2A.63 No description available WB:WBGene00198013 B0457.11 No description available WB:WBGene00198014 K09E9.9 No description available WB:WBGene00198015 T01B6.9 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198016 H21P03.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00198017 R107.10 No description available WB:WBGene00198018 Y55D5A.9 No description available WB:WBGene00198019 F57B1.14 No description available WB:WBGene00198020 C16E9.16 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by iron oxide nanoparticle; silicon dioxide nanoparticle; and Oligosaccharides based on microarray studies. WB:WBGene00198021 ZK1248.21 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198022 F15A8.9 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. WB:WBGene00198023 T14F9.13 No description available WB:WBGene00198024 H08J11.6 No description available WB:WBGene00198025 F16F9.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198026 Y71F9B.19 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00198027 K04E7.4 No description available WB:WBGene00198028 K10D6.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00198029 F54D5.20 Is affected by chd-3 based on RNA-seq studies. WB:WBGene00198030 F25G6.18 No description available WB:WBGene00198031 Y47D3B.16 No description available WB:WBGene00198032 H35N09.4 No description available WB:WBGene00198033 F09F9.11 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00198034 F36G3.7 No description available WB:WBGene00198035 Y41C4A.26 No description available WB:WBGene00198036 ZK622.9 Is affected by cep-1; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00198037 K03H4.4 No description available WB:WBGene00198038 H03E18.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00198039 T19B10.14 No description available WB:WBGene00198040 C18A3.19 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00198041 Y59E9AL.37 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00198042 T28F4.7 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00198043 ZK616.63 No description available WB:WBGene00198044 F48A11.8 No description available WB:WBGene00198045 C09H10.12 No description available WB:WBGene00198046 F19D8.10 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198047 K02A11.8 Is affected by dlc-1 and alh-4 based on RNA-seq studies. WB:WBGene00198048 Y51A2D.30 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00198049 F57G8.12 No description available WB:WBGene00198050 F29G9.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00198051 F52E4.12 Is affected by cep-1 and lpd-3 based on RNA-seq studies. WB:WBGene00198052 Y105E8A.42 Enriched in neurons based on RNA-seq studies. Is affected by Ethanol and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00198053 T05A6.12 No description available WB:WBGene00198054 B0495.17 Is affected by daf-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198055 Y75B8A.50 No description available WB:WBGene00198056 C01B7.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00198057 C06E2.14 Is affected by pgrn-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00198058 F20B10.8 No description available WB:WBGene00198059 Y39G10AL.4 No description available WB:WBGene00198060 Y51H7C.23 No description available WB:WBGene00198061 T06D10.7 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; spc-1; and set-2 based on RNA-seq studies. WB:WBGene00198062 K08A8.13 No description available WB:WBGene00198063 H05L03.7 Enriched in AVK based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198064 C31H2.8 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198065 C54D10.19 Is affected by Tunicamycin based on microarray studies. WB:WBGene00198066 F47G4.13 No description available WB:WBGene00198067 ZK617.11 Is affected by daf-2 based on microarray studies. WB:WBGene00198068 C25A11.7 Is affected by daf-2 based on microarray studies. WB:WBGene00198069 C23F12.8 No description available WB:WBGene00198070 F07G11.10 No description available WB:WBGene00198071 C12C8.6 No description available WB:WBGene00198072 F18G5.10 No description available WB:WBGene00198073 K08A8.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00198074 F47B8.17 No description available WB:WBGene00198075 F57B7.8 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00198076 R13H7.19 No description available WB:WBGene00198077 F59C12.9 No description available WB:WBGene00198078 F53B1.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00198079 F35G2.13 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198080 Y38F2AL.8 No description available WB:WBGene00198081 C09D8.8 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00198082 W06D12.8 Is affected by hpl-2 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198083 C40H5.12 Is affected by dpy-21 and met-2 based on RNA-seq studies. WB:WBGene00198084 K11G9.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198085 F47G3.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198086 F55A8.5 No description available WB:WBGene00198087 C08F8.12 No description available WB:WBGene00198088 C09D8.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198089 C24A11.11 No description available WB:WBGene00198090 C47E8.13 No description available WB:WBGene00198091 W09B12.4 No description available WB:WBGene00198092 ZC190.13 No description available WB:WBGene00198093 F55A12.14 No description available WB:WBGene00198094 Y38C1BA.5 Enriched in neurons based on RNA-seq studies. Is affected by let-418 based on RNA-seq studies. WB:WBGene00198095 F09A5.13 No description available WB:WBGene00198096 F58A3.7 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00198097 ZK1025.14 Is affected by lem-2; emr-1; and olrn-1 based on RNA-seq studies. WB:WBGene00198098 T02C5.6 No description available WB:WBGene00198099 K02H8.3 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00198100 F22E12.8 No description available WB:WBGene00198101 F52B5.9 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by dlc-1 and etr-1 based on RNA-seq studies. WB:WBGene00198102 C24A11.12 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00198103 C56E10.5 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00198104 Y58A7A.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00198105 C24D10.47 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00198106 R09F10.15 No description available WB:WBGene00198107 R03D7.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00198108 ZK1128.10 No description available WB:WBGene00198109 C30A5.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198110 C10F3.12 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00198111 ZK662.7 No description available WB:WBGene00198112 C35A11.8 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00198113 T06A1.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00198114 K02G10.11 No description available WB:WBGene00198115 C06A1.11 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198116 C24A8.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00198117 C09B7.7 No description available WB:WBGene00198118 C08C3.9 No description available WB:WBGene00198119 T02C12.6 No description available WB:WBGene00198120 K03E5.6 No description available WB:WBGene00198121 R04F11.16 No description available WB:WBGene00198122 F58F12.9 Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00198123 Y41E3.458 No description available WB:WBGene00198124 D2024.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198125 H28G03.8 No description available WB:WBGene00198126 F32G8.9 Is affected by dlc-1 and hlh-26 based on RNA-seq studies. WB:WBGene00198127 M03C11.10 Is affected by daf-2 based on microarray studies. WB:WBGene00198128 F59G1.11 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00198129 F32A6.9 No description available WB:WBGene00198130 F25H8.11 No description available WB:WBGene00198131 F36F2.11 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00198132 F56H11.11 Is affected by daf-2 based on microarray studies. WB:WBGene00198133 F07C3.14 No description available WB:WBGene00198134 H01G02.10 No description available WB:WBGene00198135 ZK525.6 No description available WB:WBGene00198136 C43F9.16 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198137 C43G2.28 No description available WB:WBGene00198138 K11H3.10 No description available WB:WBGene00198139 W04D2.9 Is affected by cep-1; ifo-1; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00198140 T05B4.17 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00198141 C16B8.7 No description available WB:WBGene00198142 F26F12.13 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198143 F12F3.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00198144 C36F7.16 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00198145 E03A3.11 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00198146 F56H6.17 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00198147 C50A2.5 No description available WB:WBGene00198148 K06G5.7 No description available WB:WBGene00198149 F58B6.7 Is affected by eat-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198150 M79.10 No description available WB:WBGene00198151 C04F12.15 No description available WB:WBGene00198152 C48A7.10 Enriched in sensory neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198153 C34F11.11 Is affected by adr-1; daf-2; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00198154 C04C11.12 Is affected by daf-2 based on microarray studies. WB:WBGene00198155 F35A5.11 No description available WB:WBGene00198156 T06H11.12 No description available WB:WBGene00198157 R11B5.7 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198158 Y60A3A.35 No description available WB:WBGene00198159 C47G2.16 Is affected by let-418 based on RNA-seq studies. WB:WBGene00198160 T06H11.13 No description available WB:WBGene00198161 C46A5.14 No description available WB:WBGene00198162 W06H8.11 Is affected by nfki-1 and etr-1 based on RNA-seq studies. WB:WBGene00198163 T21D9.5 No description available WB:WBGene00198164 F14D1.3 Enriched in neurons based on RNA-seq studies. WB:WBGene00198165 M03A1.10 No description available WB:WBGene00198166 VC5.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00198167 F38B6.12 No description available WB:WBGene00198168 T22B7.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00198169 T10H9.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00198170 Y53C10A.19 No description available WB:WBGene00198171 T04F8.13 Is affected by daf-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198172 F16F9.11 No description available WB:WBGene00198173 C14A11.10 Is affected by cep-1 and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00198174 F31F7.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and alg-1 based on RNA-seq studies. WB:WBGene00198175 ZK381.45 No description available WB:WBGene00198176 E02C12.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198177 C24A8.11 No description available WB:WBGene00198178 ZK287.12 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198179 W02B12.17 No description available WB:WBGene00198180 F16F9.12 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198181 Y73F8A.1168 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00198182 F56F3.11 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00198183 F46C5.11 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00198184 ZK381.46 No description available WB:WBGene00198185 F56D12.11 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00198186 F12D9.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00198187 T26E3.15 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198188 C11G6.6 No description available WB:WBGene00198189 W05B2.12 No description available WB:WBGene00198190 F25H2.16 No description available WB:WBGene00198191 C34H3.11 Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00198192 F19D8.5 No description available WB:WBGene00198193 C17H12.31 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and klf-1 based on RNA-seq studies. WB:WBGene00198194 F52H2.11 No description available WB:WBGene00198195 T27D12.9 Is affected by daf-2 based on microarray studies. WB:WBGene00198196 C48A7.11 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198197 F41G3.22 Is affected by set-2 based on RNA-seq studies. WB:WBGene00198198 T07H6.7 No description available WB:WBGene00198199 C12D12.9 No description available WB:WBGene00198200 C53D6.20 No description available WB:WBGene00198201 F59H5.5 No description available WB:WBGene00198202 Y18D10A.28 No description available WB:WBGene00198203 F35A5.12 No description available WB:WBGene00198204 K07A9.6 No description available WB:WBGene00198205 ZK973.18 No description available WB:WBGene00198206 Y57A10A.41 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00198207 Y48G8AL.18 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00198208 Y53H1C.8 No description available WB:WBGene00198209 K08F8.10 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00198210 D1022.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00198211 K03H4.5 Is affected by cep-1; dlc-1; and set-2 based on RNA-seq studies. WB:WBGene00198212 Y54F10BM.19 No description available WB:WBGene00198213 M03F4.12 Enriched in RID based on RNA-seq studies. Is affected by several genes including set-2; dlc-1; and unc-39 based on RNA-seq studies. WB:WBGene00198214 C17E4.17 Is affected by set-2 based on RNA-seq studies. WB:WBGene00198215 C52E4.15 No description available WB:WBGene00198216 M88.10 Is affected by cep-1 and mafr-1 based on RNA-seq and microarray studies. WB:WBGene00198217 T25E4.3 No description available WB:WBGene00198218 F59F3.10 Is affected by daf-2 based on microarray studies. WB:WBGene00198219 F13E6.9 No description available WB:WBGene00198220 C34D1.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00198221 B0414.10 No description available WB:WBGene00198222 C06A6.10 No description available WB:WBGene00198223 C54D2.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198224 Y38C1AA.16 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00198225 K03H1.19 Is affected by adr-1 and mrps-5 based on RNA-seq studies. WB:WBGene00198226 B0495.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00198227 C02D4.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198228 F21C10.14 No description available WB:WBGene00198229 C43C3.8 No description available WB:WBGene00198230 F40B5.6 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198231 T01D3.9 No description available WB:WBGene00198232 F18C5.14 Is affected by daf-2 and klf-1 based on microarray and RNA-seq studies. WB:WBGene00198233 F55F3.6 No description available WB:WBGene00198234 B0336.15 No description available WB:WBGene00198235 K01B6.8 No description available WB:WBGene00198236 C18A3.20 Enriched in SIA and SIB based on single-cell RNA-seq studies. WB:WBGene00198237 T07F12.8 No description available WB:WBGene00198238 B0207.15 No description available WB:WBGene00198239 F22H10.9 Is affected by several genes including met-2; spr-5; and tdp-1 based on RNA-seq and microarray studies. Is affected by Ethanol and antimycin based on RNA-seq studies. WB:WBGene00198240 F56E3.12 No description available WB:WBGene00198241 K02A4.7 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198242 F29F11.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00198243 C07A12.12 Is affected by pmt-2 based on microarray studies. WB:WBGene00198244 ZK1193.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198245 C46H11.12 Is affected by hmg-3 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00198246 C03E10.9 No description available WB:WBGene00198247 Y67D8C.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00198248 C18C4.14 Is affected by several genes including cep-1; set-2; and hda-2 based on RNA-seq studies. WB:WBGene00198249 C18D1.15 No description available WB:WBGene00198250 T24D11.3 No description available WB:WBGene00198251 F46H5.10 No description available WB:WBGene00198252 T25D1.5 No description available WB:WBGene00198253 T11A5.9 No description available WB:WBGene00198254 C02B4.9 Is affected by daf-2 based on microarray studies. WB:WBGene00198255 T13B5.11 No description available WB:WBGene00198256 Y47D3B.17 No description available WB:WBGene00198257 T02E9.19 Enriched in AVK based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00198258 ZK617.12 No description available WB:WBGene00198259 C34F11.12 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198260 C34E11.12 No description available WB:WBGene00198261 C29H12.9 No description available WB:WBGene00198262 D2024.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198263 T06F4.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198264 K12F2.3 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198265 Y39H10A.9 No description available WB:WBGene00198266 R173.8 No description available WB:WBGene00198267 C48E7.13 Is affected by set-2 based on RNA-seq studies. WB:WBGene00198268 F31E8.14 No description available WB:WBGene00198269 F59D12.12 Is affected by pmt-2 based on microarray studies. WB:WBGene00198270 C54A12.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00198271 F58G1.12 No description available WB:WBGene00198272 C16E9.17 Enriched in neurons based on RNA-seq studies. Is affected by klf-1 and mrps-5 based on RNA-seq studies. WB:WBGene00198273 C41A3.9 No description available WB:WBGene00198274 F40H3.10 No description available WB:WBGene00198275 K09A9.10 No description available WB:WBGene00198276 T19A5.8 Is affected by several genes including let-418; dlc-1; and mrps-5 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198277 B0041.10 No description available WB:WBGene00198278 K03C7.9 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00198279 F53B2.15 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00198280 F25D7.6 Is affected by cep-1; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00198281 Y59E1B.5 No description available WB:WBGene00198282 M02G9.6 No description available WB:WBGene00198283 F55F1.8 No description available WB:WBGene00198284 F44C4.11 No description available WB:WBGene00198285 ZK617.13 No description available WB:WBGene00198286 R151.16 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198287 F13H6.15 Enriched in neurons based on RNA-seq studies. Is affected by bcat-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198288 M70.8 No description available WB:WBGene00198289 C24A3.12 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198290 F56E3.13 No description available WB:WBGene00198291 Y51A2D.31 No description available WB:WBGene00198292 T14F9.14 No description available WB:WBGene00198293 C12D8.23 Is affected by hmg-4 and spt-16 based on RNA-seq studies. WB:WBGene00198294 T07D3.11 No description available WB:WBGene00198295 F25H10.5 No description available WB:WBGene00198296 H34C03.19 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00198297 W03G11.14 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; alg-1; and glh-1 based on RNA-seq studies. WB:WBGene00198298 F47B10.10 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00198299 F44E8.44 No description available WB:WBGene00198300 T19E7.25 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00198301 W06B3.5 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00198302 Y102A11A.10 No description available WB:WBGene00198303 F53F4.23 Enriched in neurons based on RNA-seq studies. Is affected by unc-39 based on RNA-seq studies. WB:WBGene00198304 C25F6.17 Is affected by cep-1 and dlc-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198305 R134.4 No description available WB:WBGene00198306 F12D9.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198307 F12F6.15 Enriched in NSM based on RNA-seq studies. Is affected by cep-1; dlc-1; and set-2 based on RNA-seq studies. WB:WBGene00198308 C04A11.7 No description available WB:WBGene00198309 F35D2.11 Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00198310 T08A9.17 No description available WB:WBGene00198311 Y69E1A.11 No description available WB:WBGene00198312 T21B10.10 Enriched in AVK based on RNA-seq studies. WB:WBGene00198313 C29E6.13 Enriched in AVK and neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198314 ZK867.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198315 K02A11.9 Is affected by cep-1; dlc-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00198316 K08E5.12 Is affected by dpy-21; adr-1; and set-2 based on RNA-seq studies. WB:WBGene00198317 F57B10.18 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00198318 C36C9.7 No description available WB:WBGene00198319 F22A3.13 No description available WB:WBGene00198320 Y37E11AL.15 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. WB:WBGene00198321 C09D8.10 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00198322 M153.7 No description available WB:WBGene00198323 F26A10.14 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00198324 F11A6.9 No description available WB:WBGene00198325 C33F10.20 No description available WB:WBGene00198326 R07G3.12 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 and mrps-5 based on microarray and RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198327 F37B12.8 No description available WB:WBGene00198328 Y18H1A.17 No description available WB:WBGene00198329 F42D1.9 No description available WB:WBGene00198330 F14B8.12 No description available WB:WBGene00198331 F52F10.8 Is affected by eat-2 based on microarray studies. WB:WBGene00198332 T03F7.13 No description available WB:WBGene00198333 ZK617.14 No description available WB:WBGene00198334 C16D9.14 Is affected by elli-1 and daf-2 based on microarray studies. WB:WBGene00198335 M04C9.9 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198336 F53B7.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00198337 T05G5.14 No description available WB:WBGene00198338 T25E4.4 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00198339 K01A12.6 No description available WB:WBGene00198340 F23H12.16 No description available WB:WBGene00198341 F42C5.13 Is affected by ints-8 and lpd-3 based on RNA-seq studies. WB:WBGene00198342 F41E7.14 Is affected by dpy-21 and hmg-3 based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00198343 F57A10.7 Is affected by ifo-1 based on microarray studies. WB:WBGene00198344 F54G8.7 No description available WB:WBGene00198345 Y73B3A.25 Enriched in neurons based on RNA-seq studies. WB:WBGene00198346 F34D6.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00198347 T01B10.11 No description available WB:WBGene00198348 T06E8.4 No description available WB:WBGene00198349 C45B2.12 No description available WB:WBGene00198350 T25F10.9 No description available WB:WBGene00198351 F28A12.5 Is affected by glycine and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00198352 ZK867.13 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00198353 W03B1.16 No description available WB:WBGene00198354 F11D5.17 No description available WB:WBGene00198355 F28C1.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00198356 F45B8.13 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00198357 F55G1.19 No description available WB:WBGene00198358 F02E8.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00198359 T13H10.10 No description available WB:WBGene00198360 F58H1.19 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198361 Y66A7AL.6 No description available WB:WBGene00198362 Y119D3B.23 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198363 H40L08.4 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198364 C09B8.14 No description available WB:WBGene00198365 W02B8.9 No description available WB:WBGene00198366 F11D5.18 No description available WB:WBGene00198367 C04C3.12 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00198368 C05D2.16 No description available WB:WBGene00198369 R06C1.9 No description available WB:WBGene00198370 T25F10.10 No description available WB:WBGene00198371 C16E9.18 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198372 R155.6 No description available WB:WBGene00198373 F46C8.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00198374 F14D12.9 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00198375 C36F7.17 No description available WB:WBGene00198376 K08A8.15 No description available WB:WBGene00198377 C36B1.16 No description available WB:WBGene00198378 C34H3.12 No description available WB:WBGene00198379 C15H7.8 Is affected by ifo-1 based on microarray studies. WB:WBGene00198380 T22B7.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00198381 T03G11.19 Is affected by cep-1 and mrps-5 based on RNA-seq studies. WB:WBGene00198382 F26A10.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198383 C06G1.13 No description available WB:WBGene00198384 C05E11.14 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198385 T19D2.8 No description available WB:WBGene00198386 cTel3X.3 No description available WB:WBGene00198387 ZK512.14 No description available WB:WBGene00198388 Y51H7C.24 No description available WB:WBGene00198389 W10C8.11 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198390 ZK809.12 No description available WB:WBGene00198391 D2030.14 Is affected by jmjd-5 based on RNA-seq studies. WB:WBGene00198392 K09F5.9 No description available WB:WBGene00198393 K03A1.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00198394 K04H4.12 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198395 ZC53.13 No description available WB:WBGene00198396 C27D11.3 Enriched in neurons based on RNA-seq studies. WB:WBGene00198397 C14F11.17 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198398 B0250.17 No description available WB:WBGene00198399 F01G12.12 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00198400 F08B12.8 Is affected by daf-2 based on microarray studies. WB:WBGene00198401 F47E1.12 Is affected by set-2 based on RNA-seq studies. WB:WBGene00198402 ZC487.8 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00198403 F15B9.12 No description available WB:WBGene00198404 M88.11 No description available WB:WBGene00198405 ZK185.8 No description available WB:WBGene00198406 T05C12.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198407 Y50E8A.21 Is affected by daf-2 based on microarray studies. WB:WBGene00198408 Y59A8B.30 No description available WB:WBGene00198409 Y48A6C.7 No description available WB:WBGene00198410 F26F12.14 Is affected by pmt-2 based on microarray studies. WB:WBGene00198411 C49A1.14 No description available WB:WBGene00198412 ZK381.47 Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00198413 C18A3.21 No description available WB:WBGene00198414 T22B2.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00198415 K11E4.9 Is affected by hmg-3; daf-2; and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00198416 F49E10.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00198417 T24C2.7 No description available WB:WBGene00198418 B0344.4 No description available WB:WBGene00198419 F17E5.4 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; hda-2; and etr-1 based on RNA-seq studies. WB:WBGene00198420 Y75B8A.51 No description available WB:WBGene00198421 F45F2.15 No description available WB:WBGene00198422 R11H6.8 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00198423 F26E4.17 No description available WB:WBGene00198424 C31G12.10 No description available WB:WBGene00198425 F08B12.9 No description available WB:WBGene00198426 C25D7.18 Is affected by cep-1 and alg-1 based on RNA-seq studies. WB:WBGene00198427 Y46H3D.9 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00198428 C06E1.15 No description available WB:WBGene00198429 F57B7.9 Enriched in AVK and neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198430 F08G5.14 Enriched in neurons based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00198431 F07A11.10 Enriched in sensory neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and hpl-2 based on RNA-seq studies. WB:WBGene00198432 F43C11.15 No description available WB:WBGene00198433 C34H3.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198434 C56G2.19 No description available WB:WBGene00198435 T19D12.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198436 C04H4.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00198437 H03A11.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198438 ZK836.10 Is affected by ifo-1 based on microarray studies. WB:WBGene00198439 ZK262.17 No description available WB:WBGene00198440 C05C9.9 No description available WB:WBGene00198441 F56D2.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198442 F37H8.9 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198443 Y54F10AM.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00198444 T10D4.17 No description available WB:WBGene00198445 F43G6.14 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; cep-1; and unc-30 based on RNA-seq and microarray studies. WB:WBGene00198446 T25D10.6 Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00198447 Y105C5B.1415 Is affected by daf-2 based on microarray studies. WB:WBGene00198448 D1046.11 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00198449 C14A11.11 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198450 ZK377.6 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00198451 Y51A2D.32 Is affected by pgrn-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198452 F57B1.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198453 T23F1.9 No description available WB:WBGene00198454 F28C1.13 Enriched in head mesodermal cell; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00198455 Y54G9A.14 Is affected by cep-1 and set-2 based on RNA-seq studies. WB:WBGene00198456 C30C11.10 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00198457 F58A6.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198458 H03E18.5 No description available WB:WBGene00198459 R10E11.11 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00198460 B0416.9 Is affected by cep-1; set-2; and nfki-1 based on RNA-seq studies. WB:WBGene00198461 C26E1.7 Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198462 F01D5.14 Is affected by cep-1; tdp-1; and adr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198463 C27F2.13 Enriched in AFD based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00198464 F52E10.10 Is affected by daf-2 based on microarray studies. WB:WBGene00198465 C02C6.7 Enriched in neurons based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00198466 F13H6.16 No description available WB:WBGene00198467 F58A4.20 Is affected by Ketamine based on RNA-seq studies. WB:WBGene00198468 C53D6.21 No description available WB:WBGene00198469 H12D21.17 No description available WB:WBGene00198470 F08G2.15 No description available WB:WBGene00198471 C43D7.15 No description available WB:WBGene00198472 F57F10.2 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198473 K09B11.21 Is affected by lem-2; emr-1; and mett-10 based on RNA-seq studies. WB:WBGene00198474 T10E10.11 No description available WB:WBGene00198475 K08E4.10 No description available WB:WBGene00198476 T18H9.9 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; alg-1; and mrps-5 based on RNA-seq studies. WB:WBGene00198477 F49H12.11 No description available WB:WBGene00198478 Y58A7A.11 Is affected by ifo-1 based on microarray studies. WB:WBGene00198479 Y22D7AR.19 Is affected by elli-1 based on microarray studies. WB:WBGene00198480 F54D5.21 No description available WB:WBGene00198481 Y43F8C.26 No description available WB:WBGene00198482 Y106G6D.9 No description available WB:WBGene00198483 ZK389.1 No description available WB:WBGene00198484 C55A6.17 No description available WB:WBGene00198485 ZK816.7 No description available WB:WBGene00198486 F31E3.10 No description available WB:WBGene00198487 F48C11.7 No description available WB:WBGene00198488 ZC513.17 No description available WB:WBGene00198489 F53F8.9 No description available WB:WBGene00198490 ZC250.9 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00198491 B0024.18 Is affected by dlc-1 and hlh-26 based on RNA-seq studies. WB:WBGene00198492 C47D2.3 No description available WB:WBGene00198493 T01C1.10 No description available WB:WBGene00198494 C14F11.18 No description available WB:WBGene00198495 R08B4.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198496 ZC504.12 No description available WB:WBGene00198497 F10G8.12 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; dlc-1; and bcat-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198498 R09F10.16 Is affected by several genes including lem-2; emr-1; and adr-1 based on RNA-seq studies. WB:WBGene00198499 Y37F4.12 No description available WB:WBGene00198500 R01E6.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00198501 C48C5.6 No description available WB:WBGene00198502 T23F2.8 No description available WB:WBGene00198503 Y77E11A.17 No description available WB:WBGene00198504 F33D4.13 No description available WB:WBGene00198505 T08H4.8 Is affected by eat-2 based on microarray studies. WB:WBGene00198506 F55B12.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198507 C01F4.7 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00198508 C29E6.14 Is affected by klf-1 and spr-5 based on RNA-seq studies. WB:WBGene00198509 M04B2.10 Is affected by dpy-21 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198510 Y49F6B.16 Is affected by spr-5 based on RNA-seq studies. WB:WBGene00198511 C09C7.2 No description available WB:WBGene00198512 H22K11.9 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198513 F30H5.7 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198514 T12B5.17 No description available WB:WBGene00198515 F01G12.13 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198516 F08F1.15 No description available WB:WBGene00198517 ZC53.14 No description available WB:WBGene00198518 Y45F10B.60 No description available WB:WBGene00198519 C18D1.16 No description available WB:WBGene00198520 F25B4.13 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198521 C07H6.14 Enriched in sensory neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198522 F28H6.9 Is affected by daf-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198523 C14F5.9 Enriched in neurons based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00198524 C34H3.14 No description available WB:WBGene00198525 F18A1.9 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00198526 C10G8.9 No description available WB:WBGene00198527 Y69A2AR.40 No description available WB:WBGene00198528 C44E12.4 Enriched in AVK and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198529 F46F3.10 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00198530 T26A5.10 Is affected by ints-4 based on RNA-seq studies. WB:WBGene00198531 F36G9.18 Is affected by hmg-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00198532 B0478.23 Enriched in neurons based on RNA-seq studies. WB:WBGene00198533 Y104H12D.8 No description available WB:WBGene00198534 T25D3.7 Is affected by eat-2 based on microarray studies. WB:WBGene00198535 C44H4.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198536 C16D9.15 No description available WB:WBGene00198537 Y49G5B.3 No description available WB:WBGene00198538 H14E04.7 No description available WB:WBGene00198539 T27E4.18 No description available WB:WBGene00198540 C17D12.13 No description available WB:WBGene00198541 T01H3.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and alg-1 based on RNA-seq studies. WB:WBGene00198542 C18B12.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00198543 ZC504.13 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00198544 F22F1.6 No description available WB:WBGene00198545 Y53F4B.57 No description available WB:WBGene00198546 F44E5.9 No description available WB:WBGene00198547 C44H4.10 Enriched in neurons based on RNA-seq studies. Is affected by several genes including adr-1; tdp-1; and set-9 based on RNA-seq studies. Is affected by methylmercury hydroxide based on RNA-seq studies. WB:WBGene00198548 T01G1.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198549 C34B4.13 Is affected by several genes including pgl-1; glh-1; and met-2 based on RNA-seq studies. WB:WBGene00198550 F08G2.16 No description available WB:WBGene00198551 Y38C1AA.17 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198552 R04F11.17 Is affected by cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00198553 C48D1.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00198554 T09B4.16 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00198555 R07B1.21 No description available WB:WBGene00198556 K01A12.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00198557 C41G11.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198558 ZK682.10 No description available WB:WBGene00198559 Y41E3.459 Is affected by pmt-2 based on microarray studies. WB:WBGene00198560 K04H4.13 No description available WB:WBGene00198561 Y39A3CL.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00198562 Y67D11A.3 No description available WB:WBGene00198563 T27B1.4 Is affected by prg-1 and daf-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198564 F49H12.12 Is affected by several genes including daf-16; daf-12; and prg-1 based on RNA-seq studies. WB:WBGene00198565 T26C12.8 No description available WB:WBGene00198566 C07H6.15 Is affected by fzo-1 and etr-1 based on RNA-seq studies. WB:WBGene00198567 F02D10.13 No description available WB:WBGene00198568 F53B1.12 Is affected by daf-2 based on microarray studies. WB:WBGene00198569 T19B10.15 No description available WB:WBGene00198570 W04A4.7 No description available WB:WBGene00198571 ZK867.14 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; daf-2; and etr-1 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198572 K11G12.9 No description available WB:WBGene00198573 Y17G9A.88 Is affected by lem-2; emr-1; and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00198574 ZK180.11 No description available WB:WBGene00198575 F26F4.14 Is affected by several genes including cep-1; nhr-86; and elli-1 based on RNA-seq and microarray studies. WB:WBGene00198576 F21H12.8 Is affected by ahr-1; daf-2; and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00198577 F40H3.11 No description available WB:WBGene00198578 F52B10.16 Is affected by daf-2 and mrps-5 based on microarray and RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198579 Y38H6A.8 Is affected by ifo-1 based on microarray studies. WB:WBGene00198580 Y64G10A.355 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00198581 Y94H6A.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00198582 F31E8.15 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00198583 F49E10.15 No description available WB:WBGene00198584 T02E9.20 No description available WB:WBGene00198585 F59A3.14 No description available WB:WBGene00198586 W01A8.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198587 W05B10.7 No description available WB:WBGene00198588 Y63D3A.12 No description available WB:WBGene00198589 F56A11.11 No description available WB:WBGene00198590 H30A04.4 No description available WB:WBGene00198591 F20D1.16 No description available WB:WBGene00198592 Y71H9A.4 No description available WB:WBGene00198593 K08A8.16 Is affected by set-2 based on RNA-seq studies. WB:WBGene00198594 T24B8.14 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00198595 ZK617.15 No description available WB:WBGene00198596 F42C5.14 Is affected by ints-2 and ints-4 based on RNA-seq studies. WB:WBGene00198597 Y73B6BL.276 Enriched in neurons based on RNA-seq studies. WB:WBGene00198598 W01C8.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198599 F12F6.16 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198600 T08G2.6 No description available WB:WBGene00198601 F19B6.7 No description available WB:WBGene00198602 C14F11.19 No description available WB:WBGene00198603 Y48A6B.15 No description available WB:WBGene00198604 C17G1.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198605 F22D3.8 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00198606 F41C6.12 No description available WB:WBGene00198607 C32D5.16 No description available WB:WBGene00198608 T04G9.9 No description available WB:WBGene00198609 F39B2.13 No description available WB:WBGene00198610 EGAP3.2 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00198611 Y40C5A.18 No description available WB:WBGene00198612 ZC334.15 No description available WB:WBGene00198613 F31F6.11 No description available WB:WBGene00198614 T24B8.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198615 F46F3.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198616 F14B8.13 No description available WB:WBGene00198617 ZK616.64 No description available WB:WBGene00198618 T28B4.11 No description available WB:WBGene00198619 T27A1.9 No description available WB:WBGene00198620 F11C7.9 Is affected by alh-4 and etr-1 based on RNA-seq studies. WB:WBGene00198621 F54D12.16 No description available WB:WBGene00198622 M01G4.6 No description available WB:WBGene00198623 C09B8.15 No description available WB:WBGene00198624 F58G11.9 No description available WB:WBGene00198625 K03B8.19 No description available WB:WBGene00198626 Y92C3A.7 No description available WB:WBGene00198627 F46C8.15 No description available WB:WBGene00198628 C33D12.12 No description available WB:WBGene00198629 W05E10.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198630 H06A10.3 No description available WB:WBGene00198631 T10B10.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00198632 T28B4.12 No description available WB:WBGene00198633 ZC21.12 No description available WB:WBGene00198634 T09F3.6 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00198635 F09D5.5 No description available WB:WBGene00198636 F53A9.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00198637 R90.8 No description available WB:WBGene00198638 ZK525.7 Enriched in neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00198639 F55C12.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198640 Y73B6BL.277 No description available WB:WBGene00198641 T19A5.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198642 Y39A1A.28 Is affected by etr-1 and lpd-3 based on RNA-seq studies. WB:WBGene00198643 W06B3.6 Is affected by pgrn-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00198644 F57G8.13 No description available WB:WBGene00198645 C04C11.13 No description available WB:WBGene00198646 C25B8.10 No description available WB:WBGene00198647 Y34B4A.15 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00198648 F38B7.15 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198649 Y105E8A.43 Enriched in neurons based on RNA-seq studies. WB:WBGene00198650 Y97E10AL.4 No description available WB:WBGene00198651 C30F12.9 Is affected by ins-11 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00198652 F25H8.12 No description available WB:WBGene00198653 ZC455.16 No description available WB:WBGene00198654 F26A10.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198655 Y64G10A.356 Is affected by daf-2 based on microarray studies. WB:WBGene00198656 Y37D8A.27 No description available WB:WBGene00198657 cTel29B.1 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198658 Y71H10A.3 Enriched in neurons based on RNA-seq studies. WB:WBGene00198659 C05B5.14 No description available WB:WBGene00198660 F14F3.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198661 D2023.15 Is affected by hmg-3; hmg-4; and spt-16 based on RNA-seq studies. WB:WBGene00198662 W01H2.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00198663 F36D4.11 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00198664 T01B7.12 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198665 T14G12.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198666 cTel17.2 No description available WB:WBGene00198667 ZK287.13 Is affected by set-2 based on RNA-seq studies. WB:WBGene00198668 B0496.14 No description available WB:WBGene00198669 T20B12.11 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00198670 F14F3.11 No description available WB:WBGene00198671 F02G3.4 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00198672 F58A4.21 No description available WB:WBGene00198673 Y39B6A.79 No description available WB:WBGene00198674 F25H8.13 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00198675 C10F3.13 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00198676 Y17D7C.8 No description available WB:WBGene00198677 F43D2.12 Is affected by cep-1; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00198678 F22E10.10 No description available WB:WBGene00198679 C44B7.17 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198680 F45E1.12 No description available WB:WBGene00198681 W06A7.8 Is affected by cep-1; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00198682 B0563.14 No description available WB:WBGene00198683 C31H2.9 Is affected by daf-2 based on microarray studies. WB:WBGene00198684 H13J03.2 No description available WB:WBGene00198685 F53F4.24 Is affected by adr-1 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00198686 F18E2.12 Enriched in neurons based on RNA-seq studies. Is affected by chd-3; let-418; and etr-1 based on RNA-seq studies. WB:WBGene00198687 T23B5.5 No description available WB:WBGene00198688 F28E10.12 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00198689 F13H6.17 No description available WB:WBGene00198690 F42H10.13 Is affected by daf-2 based on microarray studies. WB:WBGene00198691 F37E3.4 No description available WB:WBGene00198692 C09H10.13 Is affected by several genes including hpl-2; ikb-1; and sams-3 based on RNA-seq studies. WB:WBGene00198693 F13H10.10 No description available WB:WBGene00198694 C25A11.8 Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198695 C01C4.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00198696 Y53C12B.9 No description available WB:WBGene00198697 ZK867.15 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198698 H01G02.11 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and bcat-1 based on RNA-seq studies. WB:WBGene00198699 C06E4.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00198700 C05A9.5 Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00198701 F08F1.16 No description available WB:WBGene00198702 B0240.6 No description available WB:WBGene00198703 R193.4 No description available WB:WBGene00198704 C31H2.10 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00198705 C34D1.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00198706 M79.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198707 K02D7.7 No description available WB:WBGene00198708 C01A2.10 No description available WB:WBGene00198709 F35G2.14 Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198710 K08A2.14 No description available WB:WBGene00198711 C54C6.9 Is affected by adr-1 and set-2 based on RNA-seq studies. WB:WBGene00198712 K09A11.8 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00198713 C17H12.32 No description available WB:WBGene00198714 F10D7.8 Is affected by cep-1; chd-3; and let-418 based on RNA-seq studies. WB:WBGene00198715 Y46E12A.7 No description available WB:WBGene00198716 C18D1.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00198717 C34H3.15 No description available WB:WBGene00198718 F31F7.7 No description available WB:WBGene00198719 F48A11.9 No description available WB:WBGene00198720 W01B6.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198721 Y57E12B.5 No description available WB:WBGene00198722 C35C5.17 Is affected by daf-2 based on microarray studies. WB:WBGene00198723 B0393.15 No description available WB:WBGene00198724 K10D6.13 Enriched in neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00198725 F55A11.13 Is affected by several genes including lem-2; emr-1; and meg-3 based on RNA-seq studies. WB:WBGene00198726 K03B8.20 No description available WB:WBGene00198727 Y23H5A.10 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00198728 W04D2.10 Is affected by cep-1; etr-1; and lpd-3 based on RNA-seq studies. WB:WBGene00198729 Y46E12BL.6 No description available WB:WBGene00198730 F43D9.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198731 R04F11.18 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00198732 C13G3.8 No description available WB:WBGene00198733 F43C9.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00198734 ZK470.11 No description available WB:WBGene00198735 Y39B6A.80 No description available WB:WBGene00198736 ZC581.13 Is affected by several genes including lem-2; emr-1; and hmg-3 based on RNA-seq and microarray studies. WB:WBGene00198737 T04C9.8 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; fzo-1; and lpd-3 based on RNA-seq studies. WB:WBGene00198738 C47E12.17 No description available WB:WBGene00198739 C26B2.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198740 F56D1.11 Is affected by daf-2 and lpd-3 based on microarray and RNA-seq studies. WB:WBGene00198741 T09A5.19 No description available WB:WBGene00198742 T22B11.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00198743 B0198.6 Is affected by pgrn-1 and dpy-21 based on RNA-seq studies. WB:WBGene00198744 T26E3.16 No description available WB:WBGene00198745 H30A04.5 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00198746 F08C6.13 Enriched in AVK based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198747 VC5.9 No description available WB:WBGene00198748 M163.19 Is affected by lbp-3 based on RNA-seq studies. WB:WBGene00198749 F52D10.10 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00198750 F11H8.7 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 and mrps-5 based on RNA-seq studies. WB:WBGene00198751 K04D7.13 No description available WB:WBGene00198752 F54D12.17 No description available WB:WBGene00198753 F11E6.21 No description available WB:WBGene00198754 K04G11.8 No description available WB:WBGene00198755 T19C11.1 Is affected by daf-2 based on microarray studies. WB:WBGene00198756 F13D11.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00198757 Y105E8A.44 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198758 Y119D3B.24 No description available WB:WBGene00198759 F21C10.15 No description available WB:WBGene00198760 Y7A5A.16 No description available WB:WBGene00198761 ZK377.7 Is affected by adr-1; dlc-1; and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00198762 Y116F11B.21 No description available WB:WBGene00198763 Y39B6A.81 Is affected by Tunicamycin and silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198764 C07G1.11 Is affected by chd-3 and let-418 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198765 F54A3.10 No description available WB:WBGene00198766 F12F3.7 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198767 F26F12.15 Is affected by pgrn-1; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00198768 T24D5.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198769 T05A1.17 Is affected by pmt-2 based on microarray studies. WB:WBGene00198770 C14C11.11 No description available WB:WBGene00198771 C06H2.9 Enriched in neurons based on RNA-seq studies. Is affected by spr-5 based on RNA-seq studies. WB:WBGene00198772 T25C12.6 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00198773 K02B12.12 Is affected by cep-1; hmg-3; and hmg-4 based on RNA-seq studies. WB:WBGene00198774 ZK84.13 No description available WB:WBGene00198775 F23F1.11 No description available WB:WBGene00198776 F26A10.17 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00198777 F54C9.17 Is affected by pmt-2 based on microarray studies. WB:WBGene00198778 C35A11.9 No description available WB:WBGene00198779 C54H2.9 No description available WB:WBGene00198780 Y7A9D.64 No description available WB:WBGene00198781 C42D8.15 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00198782 C39F7.7 Is affected by hrpr-1; eat-2; and camt-1 based on RNA-seq and microarray studies. WB:WBGene00198783 F31A3.6 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00198784 M02B7.8 No description available WB:WBGene00198785 C43C3.9 Enriched in neurons based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00198786 F55D10.7 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00198787 K09F5.10 No description available WB:WBGene00198788 Y6B3B.14 No description available WB:WBGene00198789 W03G11.15 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00198790 K02G10.12 No description available WB:WBGene00198791 T16G1.16 No description available WB:WBGene00198792 R04E5.14 Is affected by daf-2 based on microarray studies. WB:WBGene00198793 T28B11.13 Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00198794 C29A12.13 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198795 B0285.16 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00198796 K08A8.17 Is affected by klf-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00198797 Y73F8A.1169 Is affected by tdp-1; daf-2; and adr-1 based on RNA-seq and microarray studies. WB:WBGene00198798 Y37A1B.332 Is affected by cep-1 and ikb-1 based on RNA-seq studies. WB:WBGene00198799 T04C10.10 No description available WB:WBGene00198800 F39E9.23 No description available WB:WBGene00198801 T05A6.13 No description available WB:WBGene00198802 ZK836.11 Is affected by ifo-1 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198803 C54D1.11 No description available WB:WBGene00198804 T28B11.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198805 Y37B11A.4 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and Zidovudine based on RNA-seq studies. WB:WBGene00198806 Y76F7A.4 No description available WB:WBGene00198807 T07F10.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198808 ZK381.48 No description available WB:WBGene00198809 T06E8.5 Enriched in neurons based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00198810 F46C8.16 Is affected by cep-1; fzo-1; and etr-1 based on RNA-seq studies. WB:WBGene00198811 C13G3.9 No description available WB:WBGene00198812 Y43D4A.162 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00198813 Y116F11A.8 No description available WB:WBGene00198814 F31C3.15 Is affected by several genes including vit-2; tdp-1; and mrps-5 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00198815 ZK180.12 Enriched in neurons based on RNA-seq studies. Is affected by emr-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00198816 C12C8.7 Is affected by elli-1 and daf-2 based on microarray studies. WB:WBGene00198817 Y82E9BR.29 No description available WB:WBGene00198818 T21C12.9 No description available WB:WBGene00198819 T22E5.14 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00198820 F35H10.16 No description available WB:WBGene00198821 T26H2.14 No description available WB:WBGene00198822 F58H1.20 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198823 Y52B11A.16 No description available WB:WBGene00198824 C09D1.4 No description available WB:WBGene00198825 C54E4.7 No description available WB:WBGene00198826 F43G9.16 Is affected by several genes including cep-1; set-2; and fzo-1 based on RNA-seq studies. WB:WBGene00198827 T16G1.17 Is affected by daf-2 based on microarray studies. WB:WBGene00198828 F25H8.14 No description available WB:WBGene00198829 C32C4.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00198830 C30A5.14 Is affected by daf-2 based on microarray studies. WB:WBGene00198831 F13H6.18 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00198832 T13H10.11 Is affected by eat-2 based on microarray studies. WB:WBGene00198833 K03H9.9 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00198834 C43G2.29 No description available WB:WBGene00198835 C18B12.13 No description available WB:WBGene00198836 H19M22.7 No description available WB:WBGene00198837 T22E5.15 No description available WB:WBGene00198838 K10C3.10 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198839 B0414.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198840 F08F3.14 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198841 T03G11.20 No description available WB:WBGene00198842 K07E3.10 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198843 T25F10.11 No description available WB:WBGene00198844 F25B5.11 No description available WB:WBGene00198845 R04F11.19 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198846 Y75B8A.52 No description available WB:WBGene00198847 F49E2.8 No description available WB:WBGene00198848 B0205.16 No description available WB:WBGene00198849 F56E3.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198850 Y62F5A.13 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198851 C07A4.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00198852 F26F12.16 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198853 C30B5.13 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198854 W03G11.16 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00198855 F59G1.12 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00198856 T25C12.7 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00198857 Y116F11A.9 No description available WB:WBGene00198858 C31H2.11 No description available WB:WBGene00198859 F37B12.9 No description available WB:WBGene00198860 C14B9.14 Is affected by daf-2 based on microarray studies. WB:WBGene00198861 C02D4.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00198862 R04F11.20 No description available WB:WBGene00198863 K09F5.11 No description available WB:WBGene00198864 Y43E12A.6 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; adr-1; and pmt-2 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198865 B0198.7 Is affected by pgrn-1 and alh-4 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00198866 Y51H7C.25 No description available WB:WBGene00198867 T13H10.12 No description available WB:WBGene00198868 T09B9.7 No description available WB:WBGene00198869 K08A8.18 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00198870 F25H10.6 No description available WB:WBGene00198871 C02E7.16 No description available WB:WBGene00198872 F20D1.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198873 F10C2.11 Enriched in AVK and neurons based on RNA-seq studies. Is affected by several genes including dlc-1; pptr-1; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00198874 T04F3.7 Is affected by daf-2; ifo-1; and klf-1 based on microarray and RNA-seq studies. WB:WBGene00198875 H30A04.6 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00198876 Y105E8A.45 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00198877 F57A10.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198878 T28B11.15 No description available WB:WBGene00198879 C04C11.14 No description available WB:WBGene00198880 VC5.10 No description available WB:WBGene00198881 C40C9.13 No description available WB:WBGene00198882 C32A9.2 No description available WB:WBGene00198883 F32B5.12 No description available WB:WBGene00198884 T19A6.5 No description available WB:WBGene00198885 F40H3.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00198886 C47C12.8 No description available WB:WBGene00198887 F58B4.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00198888 C54H2.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00198889 F10F2.11 No description available WB:WBGene00198890 F55D1.3 Enriched in sensory neurons based on RNA-seq studies. Is affected by adr-2 and camt-1 based on RNA-seq studies. WB:WBGene00198891 T06D8.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198892 C26B9.8 No description available WB:WBGene00198893 T01H8.6 Is affected by daf-2 based on microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00198894 K09A11.9 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00198895 B0284.7 Is affected by mrps-5 based on RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00198896 C07A4.9 No description available WB:WBGene00198897 C47E8.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00198898 Y42A5A.9 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198899 K08A8.19 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00198900 F33E2.11 No description available WB:WBGene00198901 Y73B6BL.278 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00198902 T07F12.9 Is affected by dpy-21 and alg-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198903 W07G9.3 No description available WB:WBGene00198904 T21H3.8 No description available WB:WBGene00198905 T07D4.6 Is affected by ints-5 and etr-1 based on RNA-seq studies. WB:WBGene00198906 R166.8 Enriched in neurons based on RNA-seq studies. Is affected by Cry5B and glycine based on microarray and RNA-seq studies. WB:WBGene00198907 M79.12 No description available WB:WBGene00198908 R13H4.10 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00198909 T24D3.3 No description available WB:WBGene00198910 F46C8.17 No description available WB:WBGene00198911 Y39G8C.8 No description available WB:WBGene00198912 ZK377.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198913 Y40B10A.10 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00198914 F25H8.15 No description available WB:WBGene00198915 C26D10.8 No description available WB:WBGene00198916 B0457.12 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00198917 K02G10.13 Is affected by Cry5B based on microarray studies. WB:WBGene00198918 Y69E1A.12 No description available WB:WBGene00198919 Y119D3B.25 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198920 C13G3.10 No description available WB:WBGene00198921 F40E10.11 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00198922 F35C12.4 No description available WB:WBGene00198923 Y37E11AL.16 No description available WB:WBGene00198924 C15F1.14 Is affected by cep-1; adr-1; and sftb-1 based on RNA-seq studies. WB:WBGene00198925 T07A5.8 Is affected by several genes including met-2; spr-5; and etr-1 based on RNA-seq studies. WB:WBGene00198926 Y77E11A.18 No description available WB:WBGene00198927 W06B11.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198928 T04C9.9 No description available WB:WBGene00198929 T12B3.8 Is affected by several genes including lag-1; let-418; and chd-3 based on RNA-seq studies. WB:WBGene00198930 Y22F5A.10 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00198931 ZK678.11 Is affected by daf-2 and lag-1 based on microarray and RNA-seq studies. WB:WBGene00198932 F29C4.11 Is affected by set-2 based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00198933 Y37A1B.333 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00198934 W02B8.10 No description available WB:WBGene00198935 B0198.8 Is affected by pgrn-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00198936 C15H9.12 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00198937 ZK287.14 No description available WB:WBGene00198938 C11G10.7 No description available WB:WBGene00198939 K04C2.9 Is affected by daf-2 based on microarray studies. WB:WBGene00198940 F31F7.8 Is affected by daf-2 based on microarray studies. WB:WBGene00198941 F43G9.17 No description available WB:WBGene00198942 B0353.2 Is affected by eat-2 and klf-1 based on microarray and RNA-seq studies. WB:WBGene00198943 F58B6.8 No description available WB:WBGene00198944 Y65A5A.25 Is affected by cep-1 and let-418 based on RNA-seq studies. WB:WBGene00198945 T08G5.18 Is affected by several genes including cep-1; set-2; and etr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00198946 C34G6.9 Is affected by cep-1; set-26; and dlc-1 based on RNA-seq studies. WB:WBGene00198947 F26A10.18 Is affected by cep-1 and adr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198948 Y60A9A.5 No description available WB:WBGene00198949 C50A2.6 No description available WB:WBGene00198950 T12D8.11 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by daf-2; camt-1; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00198951 F26F12.17 Is affected by cep-1; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00198952 F35B3.9 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00198953 F54D12.18 No description available WB:WBGene00198954 C50H2.16 No description available WB:WBGene00198955 F57G12.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. WB:WBGene00198956 R10H1.6 No description available WB:WBGene00198957 Y47H9C.18 No description available WB:WBGene00198958 C28A5.8 No description available WB:WBGene00198959 C40H5.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00198960 T19C11.2 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00198961 C54G7.13 Is affected by daf-2 based on microarray studies. WB:WBGene00198962 C14F11.20 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198963 T21D9.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00198964 K01F9.6 Is affected by several genes including cep-1; hpl-2; and etr-1 based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00198965 Y7A9D.65 No description available WB:WBGene00198966 Y39E4B.17 No description available WB:WBGene00198967 Y17D7A.5 No description available WB:WBGene00198968 Y39A3CL.12 No description available WB:WBGene00198969 cTel79B.1 No description available WB:WBGene00198970 T06H11.14 Is affected by daf-2 based on microarray studies. WB:WBGene00198971 F07F6.10 Is affected by several genes including lem-2; emr-1; and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00198972 C52G5.6 No description available WB:WBGene00198973 T14F9.15 No description available WB:WBGene00198974 C13B4.6 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00198975 C17H12.33 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198976 C35C5.18 No description available WB:WBGene00198977 T28C12.9 No description available WB:WBGene00198978 F52H2.12 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00198979 T19A5.10 Is affected by cep-1 and set-2 based on RNA-seq studies. WB:WBGene00198980 C46G7.108 Is affected by cep-1; adr-1; and ifo-1 based on RNA-seq and microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00198981 F44C4.12 No description available WB:WBGene00198982 C18A11.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198983 D1054.21 No description available WB:WBGene00198984 F46A9.8 Is affected by mrps-5 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00198985 T05A12.7 No description available WB:WBGene00198986 B0496.15 Enriched in AFD based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00198987 Y46E12BL.7 No description available WB:WBGene00198988 F38E11.22 No description available WB:WBGene00198989 C26E6.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00198990 K09F5.12 No description available WB:WBGene00198991 T05G5.15 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00198992 C18B2.8 No description available WB:WBGene00198993 T13H10.13 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00198994 B0478.24 Enriched in neurons based on RNA-seq studies. WB:WBGene00198995 W07G1.13 No description available WB:WBGene00198996 F13D11.14 Is affected by daf-2 and bcat-1 based on microarray and RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00198997 C11G10.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00198998 F20H11.6 Is affected by daf-12 and daf-2 based on tiling array and microarray studies. WB:WBGene00198999 F28B4.6 No description available WB:WBGene00199000 T24D8.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00199001 F54F11.4 No description available WB:WBGene00199002 Y51A2D.33 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00199003 F42G9.10 Enriched in sensory neurons based on RNA-seq studies. Is affected by spc-1 and unc-70 based on RNA-seq studies. WB:WBGene00199004 F39C12.7 No description available WB:WBGene00199005 Y106G6H.17 No description available WB:WBGene00199006 R186.12 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199007 C25A11.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199008 T27A3.11 Is affected by pmt-2 based on microarray studies. WB:WBGene00199009 C01C4.5 Is affected by daf-2 based on RNA-seq and microarray studies. WB:WBGene00199010 C04F1.4 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199011 T01B10.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00199012 F08F1.17 No description available WB:WBGene00199013 Y87G2A.22 No description available WB:WBGene00199014 F37H8.10 No description available WB:WBGene00199015 R02D5.14 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; adr-1; and mrps-5 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199016 W06H8.12 Enriched in AVK and neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199017 Y71G12B.36 Is affected by several genes including lem-2; pptr-1; and emr-1 based on RNA-seq studies. WB:WBGene00199018 F57C7.10 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00199019 W04D2.11 No description available WB:WBGene00199020 Y48A6B.16 Is affected by daf-2 based on microarray studies. WB:WBGene00199021 T10H4.19 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00199022 M60.10 No description available WB:WBGene00199023 K10D6.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00199024 C34F11.13 No description available WB:WBGene00199025 C09G12.18 No description available WB:WBGene00199026 T28C12.10 Is affected by mrps-5 based on RNA-seq studies. Is affected by 4-bromodiphenyl ether and Tunicamycin based on microarray studies. WB:WBGene00199027 E01G4.8 Enriched in AFD based on RNA-seq studies. WB:WBGene00199028 Y46E12A.8 No description available WB:WBGene00199029 F08G5.15 Is affected by daf-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199030 Y77E11A.19 No description available WB:WBGene00199031 F57G12.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00199032 C09H10.14 No description available WB:WBGene00199033 H30A04.7 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00199034 F56E3.15 Enriched in AVK based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00199035 F54F3.5 Is affected by cep-1 and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00199036 T03A1.5 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00199037 C06E4.17 No description available WB:WBGene00199038 C02D4.9 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00199039 F52F12.13 No description available WB:WBGene00199040 R07G3.13 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00199041 F37H8.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199042 H34C03.20 Enriched in neurons based on RNA-seq studies. WB:WBGene00199043 C49F8.10 No description available WB:WBGene00199044 K03E5.7 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199045 Y53F4B.58 Is affected by several genes including adr-1; meg-3; and etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199046 T21B6.11 Is affected by Cry5B based on microarray studies. WB:WBGene00199047 Y7A5A.17 Is affected by eat-2 based on microarray studies. WB:WBGene00199048 T06H11.15 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00199049 Y75B7AL.7 Is affected by dpy-21 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00199050 C23H5.13 No description available WB:WBGene00199051 R03E9.7 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00199052 F32A6.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00199053 T24B8.16 Is affected by ifo-1 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00199054 F49E10.16 No description available WB:WBGene00199055 F46F3.12 No description available WB:WBGene00199056 C05A9.6 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199057 C06A8.14 No description available WB:WBGene00199058 K07C10.7 No description available WB:WBGene00199059 Y22D7AL.17 No description available WB:WBGene00199060 F56E3.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00199061 W09G3.14 No description available WB:WBGene00199062 C03C11.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199063 T14B4.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199064 ZK849.7 No description available WB:WBGene00199065 C29A12.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00199066 M03E7.6 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00199067 Y39B6A.82 No description available WB:WBGene00199068 F31A3.7 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00199069 F35B12.13 No description available WB:WBGene00199070 C34G6.10 No description available WB:WBGene00199071 F52H3.9 No description available WB:WBGene00199072 C18H7.14 Is affected by daf-2 and klf-1 based on microarray and RNA-seq studies. WB:WBGene00199073 F13H6.19 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199074 F15A2.11 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00199075 H37A05.5 Is affected by nhr-86 based on RNA-seq studies. WB:WBGene00199076 K10D6.15 No description available WB:WBGene00199077 K10C3.11 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00199078 B0523.6 No description available WB:WBGene00199079 R01E6.14 Is affected by tdp-1; hmg-3; and spt-16 based on RNA-seq studies. WB:WBGene00199080 W05E10.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199081 W10C8.12 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00199082 B0454.18 Is affected by lem-2 and hpl-2 based on RNA-seq studies. WB:WBGene00199083 B0496.16 No description available WB:WBGene00199084 C11G10.9 No description available WB:WBGene00199085 F57G12.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199086 K08A8.20 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00199087 D1005.8 No description available WB:WBGene00199088 Y39G10AR.30 Is affected by cep-1; spc-1; and unc-70 based on RNA-seq studies. WB:WBGene00199089 B0395.7 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00199090 Y40C7B.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00199091 F32G8.10 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00199092 T23E7.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199093 F13H6.20 Enriched in neurons based on RNA-seq studies. WB:WBGene00199094 T24D11.4 No description available WB:WBGene00199095 T21B10.11 Enriched in AVK and neurons based on RNA-seq studies. WB:WBGene00199096 F19C6.10 No description available WB:WBGene00199097 B0403.11 No description available WB:WBGene00199098 F45E1.13 No description available WB:WBGene00199099 ZC412.11 No description available WB:WBGene00199100 Y38F2AL.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00199101 C44E12.5 Enriched in sensory neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199102 Y53F4B.59 Enriched in neurons based on RNA-seq studies. WB:WBGene00199103 Y71F9B.20 No description available WB:WBGene00199104 T24B8.17 Is affected by ifo-1 based on microarray studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00199105 F35G2.15 No description available WB:WBGene00199106 F54D7.8 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199107 K01A6.14 Enriched in neurons based on RNA-seq studies. Is affected by daf-2; met-2; and spr-5 based on microarray and RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199108 F22F1.7 Is affected by daf-2 based on microarray studies. WB:WBGene00199109 Y49F6B.17 No description available WB:WBGene00199110 C32D5.17 No description available WB:WBGene00199111 D2023.16 No description available WB:WBGene00199112 C08B11.11 No description available WB:WBGene00199113 C17D12.14 No description available WB:WBGene00199114 R166.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199115 T23E1.5 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; dlc-1; and adr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199116 C09D4.8 No description available WB:WBGene00199117 C30A5.15 No description available WB:WBGene00199118 ZC506.7 No description available WB:WBGene00199119 T19B10.16 No description available WB:WBGene00199120 ZK418.12 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00199121 F22E12.9 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199122 B0495.19 No description available WB:WBGene00199123 F45B8.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00199124 C09B9.80 No description available WB:WBGene00199125 C56A3.12 No description available WB:WBGene00199126 M03D4.76 No description available WB:WBGene00199127 R03C1.5 Is affected by chd-3 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199128 C52E4.16 No description available WB:WBGene00199129 T04F3.8 No description available WB:WBGene00199130 C17H11.7 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199131 W09G10.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00199132 C37H5.15 No description available WB:WBGene00199133 ZC250.10 No description available WB:WBGene00199134 R09F10.17 Is affected by several genes including daf-2; daf-18; and lem-2 based on RNA-seq and microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00199135 E01G6.4 No description available WB:WBGene00199136 W07G1.14 No description available WB:WBGene00199137 B0547.34 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00199138 K06A4.11 Is affected by Tunicamycin based on microarray studies. WB:WBGene00199139 W08F4.17 No description available WB:WBGene00199140 Y39A3A.8 No description available WB:WBGene00199141 R90.9 No description available WB:WBGene00199142 C09B7.8 No description available WB:WBGene00199143 F25G6.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00199144 R04E5.15 No description available WB:WBGene00199145 ZK1067.10 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00199146 Y71H9A.5 No description available WB:WBGene00199147 F44E7.14 No description available WB:WBGene00199148 C17F3.4 No description available WB:WBGene00199149 Y22F5B.1 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199150 K11G9.11 No description available WB:WBGene00199151 ZK994.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00199152 T06F4.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199153 C39E6.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199154 ZK512.15 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00199155 Y71H9A.6 No description available WB:WBGene00199156 H22K11.10 No description available WB:WBGene00199157 ZK945.12 No description available WB:WBGene00199158 C33D3.6 Is affected by eat-2 based on microarray studies. WB:WBGene00199159 W06A7.9 No description available WB:WBGene00199160 C32E12.7 No description available WB:WBGene00199161 F46C5.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00199162 ZK131.12 Is affected by hira-1 based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00199163 ZK617.16 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199164 Y75B8A.53 Is affected by eat-2 based on microarray studies. WB:WBGene00199165 T02E9.21 Is affected by cep-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199166 K08F8.11 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00199167 Y45F10B.61 Is affected by eat-2 based on microarray studies. WB:WBGene00199168 T19F4.5 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199169 F09D5.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00199170 C02D4.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00199171 C30H6.19 No description available WB:WBGene00199172 Y71D11A.8 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00199173 D1046.12 No description available WB:WBGene00199174 F13H8.14 No description available WB:WBGene00199175 C53C7.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199176 F46G11.14 No description available WB:WBGene00199177 T26H10.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; met-2; and lpd-3 based on RNA-seq studies. WB:WBGene00199178 K04H4.14 No description available WB:WBGene00199179 C44H4.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00199180 C08D8.4 No description available WB:WBGene00199181 F28B4.7 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199182 ZK1025.15 Is affected by olrn-1 based on RNA-seq studies. WB:WBGene00199183 T10D4.18 No description available WB:WBGene00199184 E02A10.8 No description available WB:WBGene00199185 VC5.11 No description available WB:WBGene00199186 K06A4.12 No description available WB:WBGene00199187 T24C2.8 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00199188 Y39A1A.29 No description available WB:WBGene00199189 F11D5.19 No description available WB:WBGene00199190 C05B5.15 No description available WB:WBGene00199191 F25D7.7 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00199192 K06A5.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00199193 F09C11.2 Enriched in sensory neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199194 C14F11.21 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00199195 F11D5.20 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199196 T01B4.6 No description available WB:WBGene00199197 W01A11.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199198 F54B11.13 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00199199 C05C9.10 Is affected by met-2 based on RNA-seq studies. WB:WBGene00199200 C37A5.12 No description available WB:WBGene00199201 Y71F9AL.19 Is affected by cep-1; pmt-2; and sams-3 based on RNA-seq and microarray studies. WB:WBGene00199202 DL2.1 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00199203 C18E9.14 No description available WB:WBGene00199204 T11F9.26 Enriched in neurons based on RNA-seq studies. WB:WBGene00199205 C04G6.14 No description available WB:WBGene00199206 F18A1.10 Enriched in sensory neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including let-418; dlc-1; and chd-3 based on RNA-seq studies. WB:WBGene00199207 F42A9.13 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00199208 F15B9.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00199209 F31D4.10 Enriched in AFD based on RNA-seq studies. WB:WBGene00199210 Y51A2B.13 No description available WB:WBGene00199211 D1081.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199212 T05A10.8 Enriched in neurons based on RNA-seq studies. Is affected by several genes including alg-1; lag-1; and dlc-1 based on RNA-seq studies. WB:WBGene00199213 F45H7.11 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00199214 W07E11.5 No description available WB:WBGene00199215 C45E1.9 Is affected by ifo-1 based on microarray studies. WB:WBGene00199216 K03B8.21 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00199217 ZK973.19 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199218 R10E12.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00199219 T08G2.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00199220 C43C3.10 No description available WB:WBGene00199221 B0393.16 Is affected by daf-2 based on microarray studies. WB:WBGene00199222 T07H6.8 No description available WB:WBGene00199223 C14F11.22 No description available WB:WBGene00199224 F52B10.17 Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq and microarray studies. WB:WBGene00199225 ZK1321.5 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00199226 F53A3.8 No description available WB:WBGene00199227 F43E12.4 No description available WB:WBGene00199228 H19M22.8 No description available WB:WBGene00199229 K08B12.10 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00199230 R173.9 No description available WB:WBGene00199231 C34H3.16 No description available WB:WBGene00199232 Y51H7C.26 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199233 C44E12.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199234 ZC504.14 Is affected by daf-2 based on microarray studies. WB:WBGene00199235 F17C8.11 No description available WB:WBGene00199236 T05A6.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199237 T25B6.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00199238 W05B10.8 No description available WB:WBGene00199239 Y55D5A.10 No description available WB:WBGene00199240 ZK381.49 No description available WB:WBGene00199241 F31F6.12 No description available WB:WBGene00199242 K02B2.35 Is affected by ifo-1 based on microarray studies. WB:WBGene00199243 F54E4.12 No description available WB:WBGene00199244 ZK973.20 Is affected by sams-3 based on RNA-seq studies. WB:WBGene00199245 H30A04.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00199246 F47B7.13 No description available WB:WBGene00199247 T27E4.19 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199248 F57B7.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00199249 F49E7.4 No description available WB:WBGene00199250 C36F7.18 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00199251 F46F2.10 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00199252 F16F9.13 No description available WB:WBGene00199253 D1046.13 No description available WB:WBGene00199254 R07D5.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and alg-1 based on RNA-seq studies. WB:WBGene00199255 T10H10.5 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199256 H36N01.2 No description available WB:WBGene00199257 Y52B11A.17 No description available WB:WBGene00199258 W06B11.9 Is affected by several genes including daf-2; cep-1; and dpy-21 based on RNA-seq and microarray studies. WB:WBGene00199259 H01G02.12 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00199260 H36L18.3 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00199261 C24A3.13 No description available WB:WBGene00199262 F53A9.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00199263 W10C4.2 No description available WB:WBGene00199264 C56C10.14 No description available WB:WBGene00199265 C05B10.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199266 Y102A11A.11 No description available WB:WBGene00199267 F43G6.15 No description available WB:WBGene00199268 C42D8.16 No description available WB:WBGene00199269 F13H6.21 Is affected by cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00199270 K03H9.10 Is affected by prg-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199271 F41G4.10 No description available WB:WBGene00199272 C25A8.9 Enriched in neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00199273 R12B2.10 No description available WB:WBGene00199274 Y54G2A.64 Is affected by dlc-1; fzo-1; and etr-1 based on RNA-seq studies. WB:WBGene00199275 AC3.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199276 C45B11.10 Is affected by several genes including his-72; his-71; and hmg-4 based on RNA-seq studies. WB:WBGene00199277 R13.8 Is affected by pmt-2 based on microarray studies. WB:WBGene00199278 F54D8.8 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00199279 Y73B3A.26 Enriched in neurons based on RNA-seq studies. WB:WBGene00199280 K07A1.19 No description available WB:WBGene00199281 C45G7.9 No description available WB:WBGene00199282 Y56A3A.38 No description available WB:WBGene00199283 F32A11.9 Is affected by tdp-1 and spt-16 based on RNA-seq studies. WB:WBGene00199284 H32C10.96 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00199285 K09E9.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00199286 W05H5.9 No description available WB:WBGene00199287 Y73B6BL.279 Is affected by cep-1; daf-2; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00199288 C47E12.18 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00199289 Y57E12B.6 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199290 ZK377.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199291 R02D5.15 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00199292 Y48A6B.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00199293 C41G11.14 Enriched in neurons based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199294 F02G3.5 Is affected by let-418 based on RNA-seq studies. WB:WBGene00199295 T19C4.22 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199296 F45D3.9 Is affected by daf-12 based on RNA-seq studies. WB:WBGene00199297 T10E9.12 Is affected by lem-2; hmg-3; and nfki-1 based on RNA-seq studies. WB:WBGene00199298 Y40C5A.19 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00199299 Y38H6A.9 Is affected by Cry5B based on microarray studies. WB:WBGene00199300 T21G5.8 Is affected by ifo-1 based on microarray studies. WB:WBGene00199301 K02A4.8 No description available WB:WBGene00199302 R11.7 Is affected by daf-2 based on microarray studies. WB:WBGene00199303 F54F7.12 No description available WB:WBGene00199304 C07G1.12 No description available WB:WBGene00199305 C39E9.18 Is affected by spt-16; sir-2.1; and let-60 based on RNA-seq and microarray studies. WB:WBGene00199306 R01E6.15 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00199307 F58H1.21 No description available WB:WBGene00199308 C05D12.10 Is affected by daf-2 based on microarray studies. WB:WBGene00199309 C09G5.10 No description available WB:WBGene00199310 K05B2.7 No description available WB:WBGene00199311 ZK816.8 Is affected by several genes including daf-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00199312 B0457.13 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00199313 C04F6.8 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199314 R02D5.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00199315 T04C12.23 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by daf-2 and lpd-3 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00199316 PDB1.2 No description available WB:WBGene00199317 Y23B4A.5 No description available WB:WBGene00199318 R13H8.3 Enriched in AFD based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00199319 F47D12.10 Is affected by hpl-2 based on tiling array studies. WB:WBGene00199320 R02D5.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00199321 B0034.12 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199322 ZK550.42 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199323 C08D8.5 No description available WB:WBGene00199324 M153.8 No description available WB:WBGene00199325 F45H7.12 Is affected by several genes including daf-2; cep-1; and prg-1 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199326 T01C8.9 No description available WB:WBGene00199327 T13H2.8 No description available WB:WBGene00199328 R10E12.7 Is affected by cep-1 based on RNA-seq studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00199329 F11D5.21 No description available WB:WBGene00199330 F31B9.5 Is affected by daf-2 based on microarray studies. WB:WBGene00199331 K12D12.9 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00199332 T23F2.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199333 F45H11.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00199334 T27E4.20 Is affected by daf-2 based on microarray studies. WB:WBGene00199335 F33C8.7 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00199336 C41C4.14 Is affected by daf-2; eat-2; and met-2 based on microarray and RNA-seq studies. WB:WBGene00199337 F42D1.10 No description available WB:WBGene00199338 F26A10.19 Is affected by adr-1; mrps-5; and alh-4 based on RNA-seq studies. Is affected by glycine and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00199339 C41G7.13 Is affected by several genes including cep-1; set-2; and ins-11 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199340 Y43F8C.27 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00199341 C50E10.12 No description available WB:WBGene00199342 F22B3.15 No description available WB:WBGene00199343 F42E11.6 No description available WB:WBGene00199344 E02C12.16 Is affected by cep-1; dlc-1; and mrps-5 based on RNA-seq studies. WB:WBGene00199345 F45B8.15 No description available WB:WBGene00199346 F16A11.7 No description available WB:WBGene00199347 F47B7.14 No description available WB:WBGene00199348 C02B4.10 No description available WB:WBGene00199349 C40H5.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00199350 F13D11.15 No description available WB:WBGene00199351 EGAP3.3 Enriched in neurons based on RNA-seq studies. WB:WBGene00199352 C26G2.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00199353 C05B10.16 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199354 C31H1.97 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199355 F56E3.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199356 R04F11.21 No description available WB:WBGene00199357 Y39G8C.9 Is affected by daf-2 and mrps-5 based on microarray and RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199358 F46H6.10 No description available WB:WBGene00199359 F35E8.19 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199360 F44E5.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00199361 B0310.7 No description available WB:WBGene00199362 F29D10.7 No description available WB:WBGene00199363 ZK945.13 No description available WB:WBGene00199364 F17H10.7 No description available WB:WBGene00199365 C17G1.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00199366 T06F4.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00199367 Y69H2.20 Is affected by set-2 based on RNA-seq studies. WB:WBGene00199368 Y38F1A.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199369 H14E04.8 No description available WB:WBGene00199370 F25B4.14 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00199371 T03F7.14 Is affected by several genes including daf-2; cep-1; and meg-3 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199372 C23H3.11 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199373 F14F3.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00199374 C07A12.13 Is affected by pmt-2 based on microarray studies. WB:WBGene00199375 C56A3.13 No description available WB:WBGene00199376 Y66A7AL.7 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00199377 F09E5.20 No description available WB:WBGene00199378 Y51A2D.34 No description available WB:WBGene00199379 B0454.19 No description available WB:WBGene00199380 F35D2.12 No description available WB:WBGene00199381 F45G2.11 No description available WB:WBGene00199382 F11D5.22 No description available WB:WBGene00199383 K01A6.15 No description available WB:WBGene00199384 F41E7.15 Enriched in neurons based on RNA-seq studies. Is affected by several genes including his-72; his-71; and etr-1 based on RNA-seq studies. WB:WBGene00199385 F52E4.13 No description available WB:WBGene00199386 C14F11.23 No description available WB:WBGene00199387 R13A1.15 No description available WB:WBGene00199388 F47F6.11 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199389 B0563.15 No description available WB:WBGene00199390 B0273.111 Enriched in neurons based on RNA-seq studies. Is affected by elli-1 and daf-2 based on microarray studies. WB:WBGene00199391 C32C4.15 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00199392 B0310.8 No description available WB:WBGene00199393 F56F10.8 Is affected by let-418 and met-2 based on RNA-seq studies. WB:WBGene00199394 K11D2.6 No description available WB:WBGene00199395 R90.10 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. WB:WBGene00199396 T27B1.5 No description available WB:WBGene00199397 M110.12 No description available WB:WBGene00199398 ZC190.14 No description available WB:WBGene00199399 F26A10.20 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00199400 C48E7.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199401 F25F2.4 Is affected by daf-2 based on microarray studies. WB:WBGene00199402 B0336.16 Enriched in AVK based on RNA-seq studies. WB:WBGene00199403 F14H12.13 No description available WB:WBGene00199404 ZK1098.13 Is affected by cep-1 and spr-5 based on RNA-seq studies. WB:WBGene00199405 T06H11.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199406 C24B9.17 No description available WB:WBGene00199407 T21E12.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00199408 T06G6.15 No description available WB:WBGene00199409 C33F10.21 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00199410 C14F11.24 Is affected by alg-1 based on RNA-seq studies. WB:WBGene00199411 Y95B8A.14 No description available WB:WBGene00199412 Y4C6B.98 Is affected by daf-2 based on microarray studies. WB:WBGene00199413 F02D10.14 No description available WB:WBGene00199414 F48E3.13 No description available WB:WBGene00199415 C07H6.16 No description available WB:WBGene00199416 Y40B1A.5 Is affected by daf-12 and zip-3 based on tiling array and RNA-seq studies. WB:WBGene00199417 W10C8.13 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00199418 T05B4.18 No description available WB:WBGene00199419 C48D5.7 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00199420 F21C10.16 No description available WB:WBGene00199421 F13H6.22 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199422 Y73A3A.2 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199423 ZK617.17 No description available WB:WBGene00199424 R11B5.8 No description available WB:WBGene00199425 C34H3.17 No description available WB:WBGene00199426 D1022.15 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199427 Y38F2AR.18 No description available WB:WBGene00199428 K01A6.16 No description available WB:WBGene00199429 F38B6.13 Enriched in neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00199430 F52F10.9 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00199431 C31G12.11 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199432 R06C1.10 No description available WB:WBGene00199433 K11E4.10 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00199434 C17H12.34 No description available WB:WBGene00199435 ZK669.8 No description available WB:WBGene00199436 F46A8.12 No description available WB:WBGene00199437 C08G9.6 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199438 W04G3.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199439 B0286.8 No description available WB:WBGene00199440 F38E9.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00199441 B0350.73 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00199442 Y69H2.21 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00199443 K06C4.21 No description available WB:WBGene00199444 Y48B6A.20 No description available WB:WBGene00199445 F57G12.10 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies. WB:WBGene00199446 F28E10.13 No description available WB:WBGene00199447 F08B12.10 Expressed in amphid neurons; head neurons; and tail neurons. WB:WBGene00199448 C04A11.8 No description available WB:WBGene00199449 F01E11.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00199450 C34F11.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199451 T19F4.6 Is affected by cep-1; dlc-1; and lpd-3 based on RNA-seq studies. WB:WBGene00199452 Y105C5A.1277 No description available WB:WBGene00199453 C01B7.13 No description available WB:WBGene00199454 F26F12.18 No description available WB:WBGene00199455 C03A7.15 Is affected by several genes including daf-2; lem-2; and emr-1 based on RNA-seq and microarray studies. WB:WBGene00199456 F13H6.23 No description available WB:WBGene00199457 R13F6.14 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199458 F29F11.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199459 C31G12.12 No description available WB:WBGene00199460 C13B9.5 Is affected by pmt-2 based on microarray studies. WB:WBGene00199461 ZK1290.20 No description available WB:WBGene00199462 B0495.20 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199463 F48A9.5 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199464 T22B7.14 Is affected by tdp-1 and hmg-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199465 T23F2.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199466 F42D1.11 No description available WB:WBGene00199467 F58D5.10 No description available WB:WBGene00199468 T01B4.7 No description available WB:WBGene00199469 M05B5.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00199470 ZK970.10 No description available WB:WBGene00199471 C17G10.11 Is affected by Tunicamycin based on microarray studies. WB:WBGene00199472 C18C4.15 No description available WB:WBGene00199473 F45E6.7 Enriched in neurons based on RNA-seq studies. Is affected by adr-1; daf-2; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00199474 ZK836.12 No description available WB:WBGene00199475 ZK112.14 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1; chd-3; and dlc-1 based on RNA-seq studies. WB:WBGene00199476 C34B4.14 Enriched in neurons based on RNA-seq studies. Is affected by bcat-1 based on RNA-seq studies. WB:WBGene00199477 T26H10.7 Enriched in neurons based on RNA-seq studies. Is affected by alg-1 and ifo-1 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199478 C01F6.13 Is affected by ints-4 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199479 H01G02.13 No description available WB:WBGene00199480 T19F4.7 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00199481 F57B7.11 No description available WB:WBGene00199482 C54D2.12 No description available WB:WBGene00199483 Y41C4A.27 Is affected by daf-2 based on microarray studies. WB:WBGene00199484 C05D9.11 No description available WB:WBGene00199485 M117.11 Enriched in AVK based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199486 Y48G8AR.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00199487 K08E4.11 No description available WB:WBGene00199488 W06H8.13 Enriched in AVK and head mesodermal cell based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00199489 C06G1.14 No description available WB:WBGene00199490 M70.9 No description available WB:WBGene00199491 F35C11.11 Is affected by eat-2 based on microarray studies. WB:WBGene00199492 Y69A2AR.41 No description available WB:WBGene00199493 C07A9.15 Is affected by cep-1 and mrps-5 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199494 ZK836.13 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00199495 C25A1.18 No description available WB:WBGene00199496 C06A6.11 Is affected by Tunicamycin based on microarray studies. WB:WBGene00199497 R155.7 No description available WB:WBGene00199498 K07E12.4 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00199499 F58G11.10 No description available WB:WBGene00199500 F09F9.12 Is affected by hmg-3; hmg-4; and spt-16 based on RNA-seq studies. WB:WBGene00199501 Y102A11A.12 No description available WB:WBGene00199502 K10D6.16 Enriched in neurons based on RNA-seq studies. Is affected by spr-5 based on RNA-seq studies. WB:WBGene00199503 C09B9.81 No description available WB:WBGene00199504 Y49G5B.4 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199505 Y106G6C.1 Is affected by cep-1 and spr-5 based on RNA-seq studies. WB:WBGene00199506 F36D1.17 No description available WB:WBGene00199507 R173.10 No description available WB:WBGene00199508 F09C3.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00199509 ZK381.50 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199510 K01A11.7 No description available WB:WBGene00199511 Y54E5B.6 Enriched in AFD based on RNA-seq studies. WB:WBGene00199512 T24H7.7 No description available WB:WBGene00199513 R08D7.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199514 C07H6.17 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199515 F56B6.7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00199516 F28D1.20 Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199517 C02C6.8 No description available WB:WBGene00199518 F22A3.14 Is affected by nhr-86 based on RNA-seq studies. WB:WBGene00199519 F01G12.14 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00199520 K08E7.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199521 F55F1.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00199522 T24A11.6 No description available WB:WBGene00199523 F25D7.8 Is affected by cep-1 and adr-1 based on RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00199524 C55B6.6 Is affected by ifo-1 based on microarray studies. WB:WBGene00199525 C03A3.5 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199526 F55E10.10 No description available WB:WBGene00199527 C31G12.13 No description available WB:WBGene00199528 F35H8.10 No description available WB:WBGene00199529 Y24D9A.12 No description available WB:WBGene00199530 B0511.15 No description available WB:WBGene00199531 C36F7.19 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199532 W03C9.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199533 D1007.22 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199534 F47C8.3 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00199535 F53F8.10 No description available WB:WBGene00199536 F28F5.13 No description available WB:WBGene00199537 F31F6.13 No description available WB:WBGene00199538 C34E11.13 No description available WB:WBGene00199539 ZK381.51 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199540 F45E4.18 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00199541 Y41E3.460 Enriched in AVK and neurons based on RNA-seq studies. Is affected by several genes including kri-1; mpk-2; and nfki-1 based on RNA-seq studies. WB:WBGene00199542 Y113G7A.19 No description available WB:WBGene00199543 H08J11.7 Is affected by daf-2 based on microarray studies. WB:WBGene00199544 F46F2.11 No description available WB:WBGene00199545 F12D9.13 No description available WB:WBGene00199546 F35D2.13 No description available WB:WBGene00199547 C24A1.5 No description available WB:WBGene00199548 Y38E10A.30 No description available WB:WBGene00199549 ZK809.13 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199550 K02E10.9 No description available WB:WBGene00199551 F57G4.13 No description available WB:WBGene00199552 F54F2.11 No description available WB:WBGene00199553 C34E7.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00199554 F49E10.17 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199555 F57C7.11 Enriched in AFD based on RNA-seq studies. WB:WBGene00199556 Y49F6A.7 No description available WB:WBGene00199557 K01F9.7 Enriched in neurons based on RNA-seq studies. Is affected by pptr-1; etr-1; and hlh-26 based on RNA-seq studies. WB:WBGene00199558 F22E12.10 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00199559 K03H9.11 No description available WB:WBGene00199560 C39B10.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199561 Y47D3B.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199562 T27B1.6 Is affected by klf-1 and mrps-5 based on RNA-seq studies. WB:WBGene00199563 C33G3.10 No description available WB:WBGene00199564 Y43H11AL.5 Is affected by tdp-1 based on RNA-seq studies. WB:WBGene00199565 F47B10.11 No description available WB:WBGene00199566 C54G4.13 No description available WB:WBGene00199567 C34E11.14 No description available WB:WBGene00199568 R03A10.11 Is affected by spr-5 based on RNA-seq studies. WB:WBGene00199569 F25F6.3 Enriched in neurons based on RNA-seq studies. WB:WBGene00199570 C43F9.17 No description available WB:WBGene00199571 T21H8.8 No description available WB:WBGene00199572 F41C6.13 No description available WB:WBGene00199573 C06A6.12 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00199574 Y41D4B.29 No description available WB:WBGene00199575 H03A11.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199576 C03H5.8 No description available WB:WBGene00199577 F22F7.9 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00199578 T28D6.13 No description available WB:WBGene00199579 C17H11.8 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199580 R03D7.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00199581 Y80D3A.12 No description available WB:WBGene00199582 ZK1025.16 No description available WB:WBGene00199583 T05B11.10 Is affected by chd-3 based on RNA-seq studies. WB:WBGene00199584 F31E8.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199585 ZK1193.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199586 K04G2.13 Enriched in ASER based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00199587 E01G6.5 No description available WB:WBGene00199588 F25H8.16 Expressed in diagonal muscle; spicule protractor muscle; spicule retractor muscle; vulval muscle; and in male. WB:WBGene00199589 C16E9.19 Enriched in sensory neurons based on RNA-seq studies. Is affected by met-2 based on RNA-seq studies. WB:WBGene00199590 F58H7.10 No description available WB:WBGene00199591 Y54G2A.65 Is affected by daf-2; unc-70; and set-2 based on microarray and RNA-seq studies. WB:WBGene00199592 ZK180.13 No description available WB:WBGene00199593 ZK867.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00199594 M60.11 Is affected by cep-1 and camt-1 based on RNA-seq studies. WB:WBGene00199595 F49E2.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199596 C49F8.11 No description available WB:WBGene00199597 F53G12.15 No description available WB:WBGene00199598 F38B6.14 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199599 K08A8.21 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199600 D1005.9 Is affected by bisphenol A based on RNA-seq studies. WB:WBGene00199601 Y55F3BR.15 No description available WB:WBGene00199602 W09C5.14 No description available WB:WBGene00199603 F13G11.144 Enriched in AFD and sensory neurons based on RNA-seq studies. WB:WBGene00199604 Y39A1B.7 Is affected by Cry5B based on microarray studies. WB:WBGene00199605 K09C8.11 Is affected by daf-2 based on microarray studies. WB:WBGene00199606 T05A6.15 Is affected by cep-1 and let-418 based on RNA-seq studies. WB:WBGene00199607 ZK973.21 No description available WB:WBGene00199608 T21B6.12 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00199609 B0414.12 No description available WB:WBGene00199610 T22B7.15 Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq and microarray studies. WB:WBGene00199611 Y51H7C.27 No description available WB:WBGene00199612 C06G1.15 Is affected by adr-1 and etr-1 based on RNA-seq studies. WB:WBGene00199613 F10E9.16 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00199614 C45B2.13 No description available WB:WBGene00199615 T04F3.9 Is affected by ints-4 and etr-1 based on RNA-seq studies. WB:WBGene00199616 C08C3.10 No description available WB:WBGene00199617 F46F3.13 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00199618 K10G6.6 No description available WB:WBGene00199619 F54E7.13 No description available WB:WBGene00199620 W05B2.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199621 B0034.13 No description available WB:WBGene00199622 T08G11.9 No description available WB:WBGene00199623 C01F4.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00199624 C02D4.11 No description available WB:WBGene00199625 F34D10.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199626 ZC317.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00199627 K03C7.10 Is affected by cep-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199628 Y7A9D.66 No description available WB:WBGene00199629 F52F12.14 Is affected by let-418 based on RNA-seq studies. WB:WBGene00199630 C09H10.15 No description available WB:WBGene00199631 F59G1.13 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00199632 C15B12.12 Is affected by cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00199633 F57F10.3 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199634 T10A3.3 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199635 Y39G10AR.31 No description available WB:WBGene00199636 F29G9.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199637 C56G3.3 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00199638 R04B3.6 Enriched in neurons based on RNA-seq studies. Is affected by unc-39 based on RNA-seq studies. WB:WBGene00199639 F56A12.8 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00199640 C31H5.8 Is affected by pmt-2 and ikb-1 based on microarray and RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199641 K09G1.5 No description available WB:WBGene00199642 T19E7.26 No description available WB:WBGene00199643 F11A1.12 Is affected by eat-2 based on microarray studies. WB:WBGene00199644 F23H12.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199645 C44B7.18 No description available WB:WBGene00199646 Y51B9A.12 No description available WB:WBGene00199647 ZK40.7 No description available WB:WBGene00199648 DY3.9 Is affected by cep-1; pmt-2; and camt-1 based on RNA-seq and microarray studies. WB:WBGene00199649 F46G11.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00199650 C54G6.7 Enriched in neurons based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199651 F09D5.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00199652 C41G11.15 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199653 B0350.74 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199654 F56E10.6 No description available WB:WBGene00199655 C30D11.2 No description available WB:WBGene00199656 F47A4.6 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00199657 C35D10.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00199658 C09D8.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by dlc-1 and set-2 based on RNA-seq studies. WB:WBGene00199659 D1044.12 Is affected by alg-1 based on RNA-seq studies. WB:WBGene00199660 E02H4.9 No description available WB:WBGene00199661 C16B8.8 Enriched in AFD and neurons based on RNA-seq studies. Is affected by hmg-3 and fzo-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00199662 W04G5.14 No description available WB:WBGene00199663 B0507.14 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; adr-1; and set-2 based on RNA-seq studies. WB:WBGene00199664 C44B12.10 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199665 K04D7.14 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199666 Y73B6BL.280 Enriched in AVK based on RNA-seq studies. WB:WBGene00199667 T04F8.14 No description available WB:WBGene00199668 R12G8.3 No description available WB:WBGene00199669 Y54E10A.25 Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199670 C10G11.14 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00199671 Y75B8A.54 No description available WB:WBGene00199672 F46G11.16 Is affected by daf-2 based on microarray studies. WB:WBGene00199673 C18H9.10 No description available WB:WBGene00199674 K10H10.14 Is affected by several genes including cep-1; prg-1; and lpd-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199675 F54F7.13 No description available WB:WBGene00199676 F42H10.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199677 C10F3.14 No description available WB:WBGene00199678 T10E10.12 No description available WB:WBGene00199679 F38G1.4 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00199680 C11G10.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00199681 Y54G9A.15 No description available WB:WBGene00199682 C04C11.15 No description available WB:WBGene00199683 Y53C10A.20 No description available WB:WBGene00199684 Y42A5A.10 No description available WB:WBGene00199685 ZK757.6 No description available WB:WBGene00199686 T25D10.7 No description available WB:WBGene00199687 C50E10.13 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00199688 C54C6.10 No description available WB:WBGene00199689 W01C8.13 No description available WB:WBGene00199690 F14D12.10 No description available WB:WBGene00199691 F56B3.14 No description available WB:WBGene00199692 R07H5.12 Is affected by cep-1 and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00199693 F31E8.17 No description available WB:WBGene00199694 2RSSE.6 Is affected by several genes including pgl-1; prg-1; and glh-1 based on RNA-seq studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00199695 F08G2.17 No description available WB:WBGene00199696 H21P03.8 Enriched in neurons based on RNA-seq studies. Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00199697 F11A6.10 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199698 K11H3.11 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on RNA-seq studies. WB:WBGene00199699 F07A11.11 No description available WB:WBGene00199700 M60.12 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00199701 R151.17 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00199702 C11E4.11 Is affected by daf-2 based on microarray studies. Is affected by Cry5B based on microarray studies. WB:WBGene00199703 F16F9.14 No description available WB:WBGene00199704 C08B6.16 No description available WB:WBGene00199705 T02E9.22 Enriched in neurons based on RNA-seq studies. WB:WBGene00199706 T02C12.7 No description available WB:WBGene00199707 C48C5.7 No description available WB:WBGene00199708 C25F6.18 No description available WB:WBGene00199709 T06F4.13 No description available WB:WBGene00199710 F55A12.15 No description available WB:WBGene00199711 ZK867.17 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199712 K02C4.9 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199713 C43G2.30 No description available WB:WBGene00199714 R02F11.6 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00199715 D1053.6 No description available WB:WBGene00199716 C05C9.11 No description available WB:WBGene00199717 T19B10.17 No description available WB:WBGene00199718 F13G3.13 No description available WB:WBGene00199719 C47F8.10 Is affected by pmt-2 and nmad-1 based on microarray and RNA-seq studies. WB:WBGene00199720 C13A10.4 No description available WB:WBGene00199721 H08J11.8 No description available WB:WBGene00199722 F47E1.13 Is affected by daf-2 based on microarray studies. WB:WBGene00199723 W07E6.7 No description available WB:WBGene00199724 F10C1.16 No description available WB:WBGene00199725 Y47D3B.19 Is affected by sodium arsenite based on RNA-seq studies. WB:WBGene00199726 F38E11.23 No description available WB:WBGene00199727 F35A5.13 No description available WB:WBGene00199728 F13H6.24 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199729 ZC513.18 No description available WB:WBGene00199730 W08D2.11 Is affected by cep-1; hsf-1; and blmp-1 based on RNA-seq studies. WB:WBGene00199731 C06G4.7 No description available WB:WBGene00199732 F34H10.6 No description available WB:WBGene00199733 C08E8.13 No description available WB:WBGene00199734 C16C2.7 Is affected by daf-2 based on microarray studies. WB:WBGene00199735 F14F11.4 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00199736 W03G11.17 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00199737 F37D6.10 No description available WB:WBGene00199738 C11G10.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199739 C32A9.3 No description available WB:WBGene00199740 F07A11.12 Is affected by several genes including pgl-1; unc-30; and glh-1 based on RNA-seq studies. WB:WBGene00199741 F22B3.16 No description available WB:WBGene00199742 T06E8.6 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00199743 F31D4.11 Is affected by daf-16 and elli-1 based on RNA-seq and microarray studies. WB:WBGene00199744 R07B5.11 Is affected by daf-2 based on microarray studies. Is affected by 4-bromodiphenyl ether and silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199745 F10F2.12 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199746 F58G11.11 Is affected by pmt-2; met-2; and spr-5 based on microarray and RNA-seq studies. WB:WBGene00199747 F54F11.5 No description available WB:WBGene00199748 R05H11.3 No description available WB:WBGene00199749 T08G2.8 No description available WB:WBGene00199750 F26D11.17 No description available WB:WBGene00199751 T05E11.10 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00199752 K12G11.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199753 Y97E10B.12 No description available WB:WBGene00199754 C27F2.14 No description available WB:WBGene00199755 Y48C3A.22 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00199756 F31F6.14 No description available WB:WBGene00199757 ZK973.22 No description available WB:WBGene00199758 F43E12.5 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00199759 F49E10.18 Is affected by daf-12; daf-16; and dpy-21 based on RNA-seq studies. WB:WBGene00199760 Y40B1B.9 No description available WB:WBGene00199761 C23H4.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1; chd-3; and lpd-3 based on RNA-seq studies. WB:WBGene00199762 T14F9.16 No description available WB:WBGene00199763 C56G3.4 Is affected by daf-2 based on microarray studies. WB:WBGene00199764 K06A1.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199765 C44E12.7 No description available WB:WBGene00199766 F56F4.10 Is affected by daf-2 based on microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00199767 Y14H12A.3 No description available WB:WBGene00199768 F52F12.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00199769 H13J03.3 No description available WB:WBGene00199770 F28B4.8 Is affected by adr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199771 F52B10.18 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199772 T14F9.17 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00199773 Y46E12BL.8 No description available WB:WBGene00199774 F14F3.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00199775 W09C5.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00199776 T28C12.11 No description available WB:WBGene00199777 C50C3.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00199778 F32B6.13 No description available WB:WBGene00199779 K08F8.12 Is affected by spr-5 and etr-1 based on RNA-seq studies. WB:WBGene00199780 R12C12.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00199781 F46A9.9 Is affected by ifo-1 based on microarray studies. Is affected by Cry5B based on microarray studies. WB:WBGene00199782 T09A5.20 No description available WB:WBGene00199783 K11D9.7 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00199784 F08G5.16 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199785 C48A7.12 Is affected by emr-1 and cep-1 based on RNA-seq studies. WB:WBGene00199786 C25F6.19 Is affected by alg-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199787 B0496.17 Enriched in AFD based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00199788 B0395.8 No description available WB:WBGene00199789 T10B10.13 Is affected by daf-2 based on microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199790 F08A8.9 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00199791 F26A1.17 No description available WB:WBGene00199792 ZK381.52 No description available WB:WBGene00199793 T24B8.18 No description available WB:WBGene00199794 ZK617.18 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199795 T28B11.16 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00199796 F40H3.13 No description available WB:WBGene00199797 C54G7.14 No description available WB:WBGene00199798 Y37A1B.334 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00199799 C49A1.15 No description available WB:WBGene00199800 C33D12.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199801 F42G10.4 Enriched in neurons based on RNA-seq studies. Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00199802 M03E7.7 No description available WB:WBGene00199803 C50C3.16 No description available WB:WBGene00199804 R03E1.5 No description available WB:WBGene00199805 F01E11.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00199806 W05E10.15 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; adr-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00199807 F28B4.9 No description available WB:WBGene00199808 F21A3.10 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00199809 R08E3.8 No description available WB:WBGene00199810 F19G12.12 Is affected by several genes including daf-2; cep-1; and tdp-1 based on RNA-seq and microarray studies. WB:WBGene00199811 F55B12.15 No description available WB:WBGene00199812 C06E4.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00199813 W09G10.8 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199814 Y47H9A.5 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199815 ZK377.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199816 C34G6.11 Is affected by adr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199817 C10B5.4 No description available WB:WBGene00199818 Y38H6A.10 Is affected by pmt-2 based on microarray studies. WB:WBGene00199819 K08F8.13 Is affected by lag-1 and etr-1 based on RNA-seq studies. WB:WBGene00199820 C34E11.15 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199821 F52H3.10 Is affected by daf-2 based on microarray studies. WB:WBGene00199822 F20D1.18 No description available WB:WBGene00199823 C45B2.14 No description available WB:WBGene00199824 Y57E12B.7 No description available WB:WBGene00199825 C18E3.10 Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00199826 W07G1.15 No description available WB:WBGene00199827 B0238.18 Is affected by klf-1 based on RNA-seq studies. Is affected by Ethanol and fluvastatin based on RNA-seq studies. WB:WBGene00199828 K10C2.10 No description available WB:WBGene00199829 C52E4.17 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00199830 T27A10.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199831 F01E11.12 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; set-2; and bcat-1 based on RNA-seq studies. WB:WBGene00199832 C44B7.19 No description available WB:WBGene00199833 K02H8.4 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00199834 Y22D7AL.18 No description available WB:WBGene00199835 F18H3.6 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00199836 C18H7.15 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199837 F14D12.11 No description available WB:WBGene00199838 T08G2.9 No description available WB:WBGene00199839 T21B6.13 No description available WB:WBGene00199840 K10C3.12 Is affected by several genes including daf-2; cep-1; and let-418 based on RNA-seq and microarray studies. WB:WBGene00199841 T12A2.19 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00199842 F38E9.9 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00199843 T22B11.9 No description available WB:WBGene00199844 D1054.22 No description available WB:WBGene00199845 F23C11.2 Is affected by pmt-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199846 F08G5.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00199847 W03G11.18 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00199848 T08B6.63 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00199849 B0496.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00199850 C02D4.12 No description available WB:WBGene00199851 C35C5.19 Is affected by set-2 and etr-1 based on RNA-seq studies. WB:WBGene00199852 Y75B7AL.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00199853 T19C11.3 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199854 ZC21.13 No description available WB:WBGene00199855 H14N18.6 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199856 F08F1.18 No description available WB:WBGene00199857 C54H2.11 No description available WB:WBGene00199858 C40H5.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00199859 F58H1.22 Is affected by set-2 based on RNA-seq studies. WB:WBGene00199860 K06H6.8 Is affected by daf-2 based on microarray studies. WB:WBGene00199861 T19H12.13 No description available WB:WBGene00199862 F59B10.8 No description available WB:WBGene00199863 Y38C1AA.18 No description available WB:WBGene00199864 F37B12.10 No description available WB:WBGene00199865 C31H2.12 No description available WB:WBGene00199866 H37A05.6 Is affected by several genes including cep-1; lag-1; and pmt-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00199867 Y43E12A.7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00199868 C28A5.9 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00199869 W05E10.16 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00199870 C28A5.10 No description available WB:WBGene00199871 F46F3.14 Enriched in germ line based on RNA-seq studies. Is affected by several genes including let-418; dlc-1; and mys-1 based on RNA-seq studies. WB:WBGene00199872 T01H8.7 No description available WB:WBGene00199873 F26E4.18 No description available WB:WBGene00199874 R10H1.7 No description available WB:WBGene00199875 C40C9.14 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00199876 F10F2.13 No description available WB:WBGene00199877 F25H8.17 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00199878 B0491.10 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; fzo-1; and etr-1 based on RNA-seq studies. WB:WBGene00199879 R04F11.22 Enriched in neurons based on RNA-seq studies. WB:WBGene00199880 C16E9.20 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199881 K01D12.17 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00199882 F47C8.4 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. Is affected by iron oxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00199883 F10C2.12 Is affected by chd-3; let-418; and dlc-1 based on RNA-seq studies. WB:WBGene00199884 F43G9.18 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00199885 B0457.14 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00199886 Y65A5A.26 No description available WB:WBGene00199887 R04E5.16 Is affected by daf-2 based on microarray studies. WB:WBGene00199888 T24E12.14 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00199889 F58F6.9 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00199890 F58H1.23 Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00199891 C29A12.15 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00199892 F37E3.5 No description available WB:WBGene00199893 C29A12.16 No description available WB:WBGene00199894 Y71H10A.4 No description available WB:WBGene00199895 F35B12.14 No description available WB:WBGene00199896 ZK287.15 Is affected by spt-16 based on RNA-seq studies. WB:WBGene00199897 R13H4.11 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00199898 Y57E12B.8 Is affected by daf-2 based on microarray studies. WB:WBGene00199899 F53G12.16 Is affected by cep-1; daf-2; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00199900 F32B5.13 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00199901 Y39G8C.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00199902 C26B9.9 No description available WB:WBGene00199903 W07E11.6 Is affected by klf-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199904 K04H4.15 No description available WB:WBGene00199905 B0198.9 Is affected by pgrn-1 and cep-1 based on RNA-seq studies. WB:WBGene00199906 T24D3.4 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00199907 Y40H7A.308 No description available WB:WBGene00199908 T25C12.8 Is affected by cep-1 and fzo-1 based on RNA-seq studies. WB:WBGene00199909 T28H10.5 No description available WB:WBGene00199910 C56G7.4 No description available WB:WBGene00199911 K09F5.13 Is affected by met-2; spr-5; and lpd-3 based on RNA-seq studies. WB:WBGene00199912 F57B9.12 No description available WB:WBGene00199913 C39F7.8 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 and etr-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00199914 T22B7.16 Is affected by tdp-1; hmg-3; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00199915 T19A6.6 No description available WB:WBGene00199916 R04E5.17 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00199917 F15A8.10 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199918 mir-8192 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by set-2; hda-2; and hlh-26 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199919 Y37A1B.335 Enriched in AVK and neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199920 F46C3.8 Is affected by eat-2 based on microarray studies. WB:WBGene00199921 F45B8.16 No description available WB:WBGene00199922 ZC64.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199923 K04G2.14 Is affected by chd-3; let-418; and dlc-1 based on RNA-seq studies. WB:WBGene00199924 C38H2.4 No description available WB:WBGene00199925 F55E10.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00199926 W07G4.10 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and met-2 based on RNA-seq studies. WB:WBGene00199927 Y77E11A.20 No description available WB:WBGene00199928 F52F12.16 Is affected by daf-2 based on microarray studies. WB:WBGene00199929 F33E2.12 No description available WB:WBGene00199930 T22H2.7 Is affected by ifo-1 based on microarray studies. WB:WBGene00199931 W02B8.11 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199932 B0273.112 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by Tunicamycin and Oligosaccharides based on microarray studies. WB:WBGene00199933 F58B6.9 No description available WB:WBGene00199934 M163.20 No description available WB:WBGene00199935 F13E6.10 Is affected by several genes including hpl-2; pmt-2; and mrps-5 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199936 Y62F5A.14 No description available WB:WBGene00199937 T04C9.10 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00199938 Y15E3A.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199939 T06H11.17 No description available WB:WBGene00199940 2RSSE.7 Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00199941 Y51A2B.14 No description available WB:WBGene00199942 B0365.8 No description available WB:WBGene00199943 C28A5.11 No description available WB:WBGene00199944 C18B12.14 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00199945 F14F3.14 No description available WB:WBGene00199946 F52B5.10 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 and etr-1 based on RNA-seq studies. WB:WBGene00199947 C18A11.12 Is affected by set-2 based on RNA-seq studies. WB:WBGene00199948 W01H2.8 Enriched in AFD and neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00199949 C06E7.91 Enriched in neurons based on RNA-seq studies. WB:WBGene00199950 F46C8.18 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00199951 D1046.14 No description available WB:WBGene00199952 F47C8.5 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and bcat-1 based on RNA-seq studies. WB:WBGene00199953 F38H4.14 No description available WB:WBGene00199954 F25H10.7 No description available WB:WBGene00199955 F45D3.10 Is affected by pmt-2 and crh-1 based on microarray and RNA-seq studies. WB:WBGene00199956 ZK180.14 No description available WB:WBGene00199957 H02I12.11 No description available WB:WBGene00199958 F09E5.21 No description available WB:WBGene00199959 R08B4.11 No description available WB:WBGene00199960 C11G10.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00199961 C09B8.16 No description available WB:WBGene00199962 Y51H7C.28 No description available WB:WBGene00199963 T26H2.15 No description available WB:WBGene00199964 T05A6.16 No description available WB:WBGene00199965 W04E12.11 No description available WB:WBGene00199966 H30A04.9 No description available WB:WBGene00199967 H21P03.9 No description available WB:WBGene00199968 K12F2.4 No description available WB:WBGene00199969 T04A6.7 No description available WB:WBGene00199970 F08F3.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00199971 T08G11.10 No description available WB:WBGene00199972 Y102A11A.13 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and set-2 based on RNA-seq studies. WB:WBGene00199973 Y73B6BL.281 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00199974 C14F11.25 Enriched in sensory neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. WB:WBGene00199975 F09F9.13 No description available WB:WBGene00199976 T04C12.24 Is affected by pmt-2 based on microarray studies. WB:WBGene00199977 R07A4.5 No description available WB:WBGene00199978 H36N01.3 Is affected by pmt-2 based on microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00199979 Y116F11B.22 No description available WB:WBGene00199980 Y59A8B.31 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00199981 F26A1.18 Is affected by tdp-1 based on RNA-seq studies. WB:WBGene00199982 C34F11.15 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00199983 T04C12.25 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00199984 F14D2.18 No description available WB:WBGene00199985 T02E9.23 Enriched in neurons based on RNA-seq studies. WB:WBGene00199986 K09E9.11 No description available WB:WBGene00199987 Y37F4.13 No description available WB:WBGene00199988 T25B6.10 No description available WB:WBGene00199989 D2024.16 No description available WB:WBGene00199990 ZC504.15 No description available WB:WBGene00199991 Y61A9LA.13 No description available WB:WBGene00199992 M05B5.9 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00199993 F45H7.13 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. WB:WBGene00199994 H36L18.4 Is affected by set-2 based on RNA-seq studies. WB:WBGene00199995 C34D1.12 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00199996 C45G7.10 No description available WB:WBGene00199997 H32C10.97 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00199998 D1081.16 Is affected by Tunicamycin and Oligosaccharides based on microarray studies. WB:WBGene00199999 Y80D3A.13 No description available WB:WBGene00200000 C02D4.13 Is affected by cep-1 and hmg-3 based on RNA-seq studies. WB:WBGene00200001 T06D8.14 No description available WB:WBGene00200002 C25F6.20 No description available WB:WBGene00200003 K08B12.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200004 ZK131.13 Is affected by hira-1 based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00200005 C07G1.13 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00200006 F49E10.19 No description available WB:WBGene00200007 F40G9.21 No description available WB:WBGene00200008 Y54G2A.66 Is affected by unc-30 based on RNA-seq studies. WB:WBGene00200009 C29H12.10 Enriched in head mesodermal cell and neurons based on RNA-seq studies. Is affected by cep-1 and met-2 based on RNA-seq studies. WB:WBGene00200010 C30B5.14 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00200011 ZK836.14 No description available WB:WBGene00200012 Y95D11A.4 No description available WB:WBGene00200013 F40E10.12 No description available WB:WBGene00200014 F07C3.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00200015 Y71H2AL.3 Is affected by met-2 and spr-5 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200016 AC3.16 Is affected by several genes including daf-2; lem-2; and blmp-1 based on RNA-seq and microarray studies. WB:WBGene00200017 F44E5.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00200018 T12G3.9 No description available WB:WBGene00200019 F43D2.13 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200020 F46F2.12 Enriched in AFD; ASER; PLM; neurons; and sensory neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00200021 Y73B3A.27 No description available WB:WBGene00200022 C55B7.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200023 C34E11.16 Is affected by daf-2 based on microarray studies. WB:WBGene00200024 Y71A12B.29 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200025 T04C12.26 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200026 R07D5.7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00200027 Y42H9B.6 No description available WB:WBGene00200028 F41G4.11 Is affected by eat-2 and pmt-2 based on microarray studies. WB:WBGene00200029 C40H1.10 Is affected by tdp-1; hmg-3; and spt-16 based on RNA-seq studies. WB:WBGene00200030 F54E4.13 No description available WB:WBGene00200031 C08G9.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00200032 F55C10.10 Is affected by etr-1 based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00200033 Y47D3B.20 No description available WB:WBGene00200034 C03C11.7 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200035 Y59C2A.4 No description available WB:WBGene00200036 R02D5.18 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00200037 T21G5.9 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00200038 F59B2.18 No description available WB:WBGene00200039 Y40C5A.20 No description available WB:WBGene00200040 F02G3.6 Enriched in neurons based on RNA-seq studies. Is affected by alh-4 based on RNA-seq studies. WB:WBGene00200041 R03E9.8 No description available WB:WBGene00200042 C12D12.10 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200043 C23H5.14 No description available WB:WBGene00200044 ZK682.11 Enriched in AVK based on RNA-seq studies. Is affected by nfki-1 and met-2 based on RNA-seq studies. WB:WBGene00200045 C02B4.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00200046 Y47G6A.34 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200047 F35B12.15 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00200048 Y47H9C.19 No description available WB:WBGene00200049 R11F4.6 No description available WB:WBGene00200050 C47D2.4 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200051 ZK836.15 Is affected by ifo-1 and spc-1 based on microarray and RNA-seq studies. WB:WBGene00200052 Y51H7C.29 No description available WB:WBGene00200053 C01B7.14 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200054 C05G6.5 No description available WB:WBGene00200055 R01E6.16 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200056 F58E6.15 No description available WB:WBGene00200057 K04G7.13 Is affected by ints-4 based on RNA-seq studies. WB:WBGene00200058 K02A4.9 Is affected by daf-2 based on RNA-seq and microarray studies. WB:WBGene00200059 K02B2.36 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200060 F20A1.14 No description available WB:WBGene00200061 Y48B6A.21 No description available WB:WBGene00200062 C25F6.21 Is affected by daf-2 based on microarray studies. WB:WBGene00200063 C43C3.11 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00200064 F13A7.15 No description available WB:WBGene00200065 F12D9.14 No description available WB:WBGene00200066 C34H3.18 No description available WB:WBGene00200067 Y54E5B.7 No description available WB:WBGene00200068 C54G7.15 No description available WB:WBGene00200069 Y50D7A.16 No description available WB:WBGene00200070 K06C4.22 No description available WB:WBGene00200071 T19C4.23 No description available WB:WBGene00200072 F56D1.12 No description available WB:WBGene00200073 T06A1.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00200074 K09H11.12 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200075 F13G11.145 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200076 T24D11.5 No description available WB:WBGene00200077 F01G12.15 Is affected by tdp-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200078 K03F8.3 Is affected by daf-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200079 C30B5.15 No description available WB:WBGene00200080 C32D5.18 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; kri-1; and mpk-2 based on RNA-seq studies. WB:WBGene00200081 T14B4.15 No description available WB:WBGene00200082 F22F1.8 Is affected by elli-1; daf-2; and pmt-2 based on microarray studies. WB:WBGene00200083 Y110A2AL.19 Enriched in neurons based on RNA-seq studies. Is affected by prg-1 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00200084 ZK39.11 No description available WB:WBGene00200085 Y39A3CL.13 No description available WB:WBGene00200086 F11D5.23 No description available WB:WBGene00200087 H08J11.9 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200088 F13H6.25 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200089 F44A2.10 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200090 K06A4.13 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00200091 Y48A6B.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00200092 Y43F8A.8 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00200093 Y105E8A.46 No description available WB:WBGene00200094 Y80D3A.14 No description available WB:WBGene00200095 F28F9.12 No description available WB:WBGene00200096 M01E5.8 Is affected by daf-2 based on microarray studies. WB:WBGene00200097 C26G2.7 No description available WB:WBGene00200098 Y71F9AL.20 No description available WB:WBGene00200099 ZK632.16 Is affected by pmt-2 based on microarray studies. WB:WBGene00200100 K03C7.11 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00200101 R06C1.11 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00200102 M70.10 No description available WB:WBGene00200103 M03D4.77 No description available WB:WBGene00200104 F54D7.9 Is affected by pmt-2 and hlh-26 based on microarray and RNA-seq studies. WB:WBGene00200105 W08F4.18 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200106 M03A1.11 No description available WB:WBGene00200107 K02C4.10 No description available WB:WBGene00200108 B0454.20 No description available WB:WBGene00200109 F25H8.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200110 F52D10.11 No description available WB:WBGene00200111 R09F10.18 Is affected by tdp-1 and daf-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200112 F14H8.10 Is affected by daf-2 and pmt-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200113 H06I04.12 No description available WB:WBGene00200114 Y48G9A.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00200115 Y53F4B.60 No description available WB:WBGene00200116 R90.11 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and fzo-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200117 F27C1.16 Is affected by Tunicamycin based on microarray studies. WB:WBGene00200118 F38B6.15 No description available WB:WBGene00200119 ZC506.8 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200120 K02D7.8 Is affected by daf-2 based on microarray studies. WB:WBGene00200121 F40H3.14 Enriched in sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200122 T04F3.10 No description available WB:WBGene00200123 C29A12.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00200124 F36D1.18 No description available WB:WBGene00200125 C24H11.11 Is affected by Tunicamycin based on microarray studies. WB:WBGene00200126 T24B8.19 Is affected by spr-5 based on RNA-seq studies. WB:WBGene00200127 E01G6.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200128 F37H8.12 No description available WB:WBGene00200129 F49E10.20 Is affected by daf-2 based on microarray studies. WB:WBGene00200130 F25H8.19 No description available WB:WBGene00200131 K07C5.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200132 ZC412.12 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00200133 R12B2.11 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00200134 T24A11.7 Is affected by pmt-2 based on microarray studies. WB:WBGene00200135 F32G8.11 Is affected by daf-2 based on microarray studies. WB:WBGene00200136 C04A2.9 No description available WB:WBGene00200137 W07G1.16 No description available WB:WBGene00200138 F15A8.11 Is affected by Cry5B based on microarray studies. WB:WBGene00200139 K08A2.15 No description available WB:WBGene00200140 C04C3.13 No description available WB:WBGene00200141 F09F9.14 No description available WB:WBGene00200142 C54D10.20 Enriched in neurons based on RNA-seq studies. WB:WBGene00200143 F25H8.20 No description available WB:WBGene00200144 F07E5.11 No description available WB:WBGene00200145 K04D7.15 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and bcat-1 based on RNA-seq studies. WB:WBGene00200146 Y75B8A.55 Enriched in neurons based on RNA-seq studies. WB:WBGene00200147 F59F5.8 Is affected by cyc-1 based on microarray studies. WB:WBGene00200148 T24D8.13 No description available WB:WBGene00200149 F28F5.14 No description available WB:WBGene00200150 C07A9.16 Is affected by cep-1; etr-1; and hlh-26 based on RNA-seq studies. WB:WBGene00200151 C39E6.12 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200152 C45B2.15 No description available WB:WBGene00200153 F46C5.13 No description available WB:WBGene00200154 F37B12.11 Is affected by several genes including cep-1; set-2; and adr-1 based on RNA-seq studies. WB:WBGene00200155 R13.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00200156 C06A12.17 No description available WB:WBGene00200157 C27D6.13 No description available WB:WBGene00200158 Y106G6G.9 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00200159 T23B3.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00200160 T28B11.17 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00200161 K01A6.17 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and alh-4 based on RNA-seq studies. WB:WBGene00200162 K02F3.13 Is affected by glycine based on RNA-seq studies. WB:WBGene00200163 C05C9.12 No description available WB:WBGene00200164 T14G10.10 Is affected by fzo-1 and etr-1 based on RNA-seq studies. WB:WBGene00200165 C37A5.13 No description available WB:WBGene00200166 K11G9.12 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200167 F45D3.11 Is affected by etr-1 based on RNA-seq studies. Is affected by sodium arsenite and Cry5B based on RNA-seq and microarray studies. WB:WBGene00200168 VC5.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00200169 K07H8.15 No description available WB:WBGene00200170 DL2.2 No description available WB:WBGene00200171 ZK1025.17 No description available WB:WBGene00200172 K01A6.18 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00200173 T27F7.6 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00200174 F17E9.17 No description available WB:WBGene00200175 R01E6.17 No description available WB:WBGene00200176 T19A5.11 Is affected by cep-1 and fhod-1 based on RNA-seq studies. WB:WBGene00200177 C52G5.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00200178 H22K11.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00200179 H30A04.10 No description available WB:WBGene00200180 F11D5.24 Is affected by cep-1; alg-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200181 ZK637.19 Is affected by pmt-2 based on microarray studies. WB:WBGene00200182 T24C2.9 No description available WB:WBGene00200183 F11D5.25 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200184 B0403.12 Is affected by daf-2 based on microarray studies. WB:WBGene00200185 Y4C6B.99 No description available WB:WBGene00200186 T19D2.9 No description available WB:WBGene00200187 C48A7.13 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00200188 F11C1.14 Enriched in AVK based on RNA-seq studies. WB:WBGene00200189 K02D3.5 No description available WB:WBGene00200190 F16F9.15 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00200191 C44H4.12 Enriched in neurons based on RNA-seq studies. Is affected by hmg-3 and set-2 based on RNA-seq studies. WB:WBGene00200192 ZC443.8 No description available WB:WBGene00200193 F37B12.12 No description available WB:WBGene00200194 T27A10.10 No description available WB:WBGene00200195 Y71H9A.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00200196 C17G1.12 Is affected by daf-2 based on microarray studies. WB:WBGene00200197 W07G1.17 No description available WB:WBGene00200198 T21C12.10 No description available WB:WBGene00200199 C54D2.13 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00200200 F09F3.16 No description available WB:WBGene00200201 T19E7.27 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00200202 Y49G5B.5 No description available WB:WBGene00200203 D2092.13 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00200204 F57F5.7 Is affected by set-2 based on RNA-seq studies. WB:WBGene00200205 C05D2.17 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200206 C03B8.6 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00200207 F28E10.14 No description available WB:WBGene00200208 C47D2.5 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200209 F32A6.11 No description available WB:WBGene00200210 F23H12.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200211 B0034.14 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00200212 F17C8.12 Is affected by several genes including cep-1; set-2; and adr-1 based on RNA-seq studies. WB:WBGene00200213 B0286.9 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. WB:WBGene00200214 C17H12.35 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00200215 T19F4.8 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200216 F58G4.8 No description available WB:WBGene00200217 C17G10.12 No description available WB:WBGene00200218 F25F1.3 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200219 T06A1.10 No description available WB:WBGene00200220 Y48B6A.22 No description available WB:WBGene00200221 F36D4.12 No description available WB:WBGene00200222 Y39A1B.8 No description available WB:WBGene00200223 ZC518.7 No description available WB:WBGene00200224 F01E11.13 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00200225 T24A11.8 No description available WB:WBGene00200226 C15B12.13 No description available WB:WBGene00200227 F56E10.7 Is affected by daf-2 based on microarray studies. WB:WBGene00200228 F57F4.6 No description available WB:WBGene00200229 F38E9.10 No description available WB:WBGene00200230 Y69H2.22 No description available WB:WBGene00200231 T10B9.12 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00200232 R06C1.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00200233 Y42H9B.7 Is affected by several genes including daf-2; eat-2; and let-418 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200234 ZK512.16 No description available WB:WBGene00200235 C08G9.8 No description available WB:WBGene00200236 ZK795.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00200237 Y57G11A.225 Enriched in neurons based on RNA-seq studies. WB:WBGene00200238 W02G9.6 No description available WB:WBGene00200239 F38B6.16 No description available WB:WBGene00200240 B0344.5 No description available WB:WBGene00200241 K06G5.8 No description available WB:WBGene00200242 F15A8.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200243 Y106G6E.7 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and camt-1 based on RNA-seq studies. WB:WBGene00200244 K06C4.23 Is affected by Tunicamycin and Cry5B based on microarray studies. WB:WBGene00200245 ZK1290.21 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00200246 M70.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00200247 VF15C11L.1 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200248 ZK617.19 No description available WB:WBGene00200249 F12F3.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and camt-1 based on RNA-seq studies. WB:WBGene00200250 ZK867.18 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00200251 R12B2.12 Is affected by cep-1; pmt-2; and lpd-3 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00200252 F31B12.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200253 C01G8.10 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00200254 Y106G6D.10 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00200255 F35H8.11 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200256 R10E12.8 No description available WB:WBGene00200257 B0350.75 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and met-2 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200258 Y54G11A.18 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00200259 R02D5.19 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by alg-1 based on RNA-seq studies. WB:WBGene00200260 W06F12.6 No description available WB:WBGene00200261 F26F12.19 Enriched in neurons based on RNA-seq studies. Is affected by let-418 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200262 C44E4.10 No description available WB:WBGene00200263 K03C7.12 No description available WB:WBGene00200264 W10C8.14 No description available WB:WBGene00200265 C17E4.18 Enriched in neurons based on RNA-seq studies. Is affected by bcat-1 and etr-1 based on RNA-seq studies. WB:WBGene00200266 K02A4.10 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200267 Y69A2AR.42 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200268 F01G12.16 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by pgrn-1 and tdp-1 based on RNA-seq studies. WB:WBGene00200269 Y15E3A.10 No description available WB:WBGene00200270 F43B10.3 No description available WB:WBGene00200271 ZK370.10 Enriched in neurons based on RNA-seq studies. Is affected by alg-1 based on RNA-seq studies. WB:WBGene00200272 C09B9.82 No description available WB:WBGene00200273 C07E3.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00200274 M03A1.12 Is affected by dpy-21 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200275 F16F9.16 No description available WB:WBGene00200276 F15H9.9 No description available WB:WBGene00200277 F36D1.19 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200278 R05H11.4 No description available WB:WBGene00200279 K01B6.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200280 F53B7.12 Is affected by pmt-2 and camt-1 based on microarray and RNA-seq studies. WB:WBGene00200281 ZK836.16 Is affected by spc-1 based on RNA-seq studies. WB:WBGene00200282 D2024.17 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00200283 C06A6.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200284 T18D3.13 Is affected by lbp-3 based on RNA-seq studies. WB:WBGene00200285 F55F1.10 No description available WB:WBGene00200286 C49A1.16 No description available WB:WBGene00200287 K03E6.8 Is affected by daf-2 based on RNA-seq studies. WB:WBGene00200288 ZK381.53 Is affected by Cry5B based on microarray studies. WB:WBGene00200289 F47B10.12 No description available WB:WBGene00200290 B0511.16 Is affected by adr-1 and set-2 based on RNA-seq studies. WB:WBGene00200291 C05E7.5 No description available WB:WBGene00200292 F57F10.4 Enriched in sensory neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00200293 C24A3.14 Enriched in AVK based on RNA-seq studies. WB:WBGene00200294 Y71F9AL.21 Enriched in AFD based on RNA-seq studies. WB:WBGene00200295 T27F7.7 No description available WB:WBGene00200296 M79.13 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00200297 C48C5.8 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00200298 T02C12.8 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00200299 C25F6.22 Is affected by Tunicamycin and Oligosaccharides based on microarray studies. WB:WBGene00200300 F55A12.16 Is affected by cep-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00200301 F49B2.8 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200302 F18A11.11 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00200303 F29F11.14 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200304 R155.8 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00200305 H28G03.9 Is affected by daf-3 based on RNA-seq studies. WB:WBGene00200306 F10D7.9 Is affected by unc-30 based on RNA-seq studies. WB:WBGene00200307 Y48G8AR.6 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200308 C56C10.15 Is affected by sams-3 based on RNA-seq studies. WB:WBGene00200309 C46F4.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00200310 Y71F9B.21 No description available WB:WBGene00200311 Y17G7A.4 No description available WB:WBGene00200312 F42C5.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200313 F09F9.15 No description available WB:WBGene00200314 K03A11.7 No description available WB:WBGene00200315 C52G5.8 No description available WB:WBGene00200316 C30D11.3 Is affected by hydrogen sulfide based on microarray studies. WB:WBGene00200317 C36F7.20 Is affected by daf-2 based on microarray studies. WB:WBGene00200318 T22B2.9 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00200319 T13H2.9 No description available WB:WBGene00200320 Y59A8B.32 Is affected by set-2 based on RNA-seq studies. WB:WBGene00200321 C02B4.12 No description available WB:WBGene00200322 Y119D3B.26 No description available WB:WBGene00200323 K02E10.10 No description available WB:WBGene00200324 F45B8.17 No description available WB:WBGene00200325 C54A12.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00200326 F42D1.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00200327 C26G2.8 No description available WB:WBGene00200328 T10A3.4 No description available WB:WBGene00200329 F43E12.6 No description available WB:WBGene00200330 F42G4.9 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00200331 C08D8.6 Is affected by cep-1 and klf-1 based on RNA-seq studies. WB:WBGene00200332 Y50D4A.8 No description available WB:WBGene00200333 F26A10.21 No description available WB:WBGene00200334 T06H11.18 No description available WB:WBGene00200335 T02E9.24 No description available WB:WBGene00200336 ZK945.14 No description available WB:WBGene00200337 C41C4.15 Is affected by prg-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200338 F41D9.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200339 F31B12.7 No description available WB:WBGene00200340 F28F9.13 No description available WB:WBGene00200341 W01A11.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200342 C42D8.17 No description available WB:WBGene00200343 F53G2.10 No description available WB:WBGene00200344 F13D11.16 No description available WB:WBGene00200345 ZK270.3 No description available WB:WBGene00200346 F43D2.14 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00200347 T28B11.18 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00200348 F26A10.22 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00200349 T27D12.10 No description available WB:WBGene00200350 Y51A2D.35 No description available WB:WBGene00200351 Y50D4C.9 Enriched in AFD based on RNA-seq studies. WB:WBGene00200352 F49C5.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00200353 T09E11.13 No description available WB:WBGene00200354 T13H10.14 Is affected by alg-1 based on RNA-seq studies. WB:WBGene00200355 F22A3.15 Is affected by several genes including cep-1; dlc-1; and pmt-2 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200356 R11E3.15 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00200357 R03A10.12 No description available WB:WBGene00200358 C17G1.13 Enriched in AFD and neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200359 F18E2.13 No description available WB:WBGene00200360 R11B5.9 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200361 C34H3.19 No description available WB:WBGene00200362 F14F3.15 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200363 Y69H2.23 No description available WB:WBGene00200364 ZC581.14 No description available WB:WBGene00200365 F16A11.8 Is affected by dlc-1 and etr-1 based on RNA-seq studies. WB:WBGene00200366 K08A8.22 Is affected by set-2 based on RNA-seq studies. WB:WBGene00200367 Y42A5A.11 No description available WB:WBGene00200368 T06F4.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00200369 Y73F8A.1170 Is affected by Tunicamycin based on microarray studies. WB:WBGene00200370 T04C12.27 No description available WB:WBGene00200371 Y67D11A.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00200372 E01G6.7 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00200373 VC5.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00200374 Y66A7AL.8 Is affected by let-418 based on RNA-seq studies. WB:WBGene00200375 T24H10.11 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00200376 Y51H7C.30 No description available WB:WBGene00200377 F46H6.11 No description available WB:WBGene00200378 F22B3.17 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200379 F13H6.26 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00200380 F14H12.14 No description available WB:WBGene00200381 F02E8.9 Is affected by pmt-2 based on microarray studies. WB:WBGene00200382 T24D5.10 No description available WB:WBGene00200383 Y38F2AR.19 No description available WB:WBGene00200384 C31H2.13 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200385 C06A12.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00200386 T27F7.8 No description available WB:WBGene00200387 F36D1.20 No description available WB:WBGene00200388 R05G6.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200389 T02E9.25 No description available WB:WBGene00200390 R08B4.12 Is affected by cep-1 and elli-1 based on RNA-seq and microarray studies. WB:WBGene00200391 C40H1.11 No description available WB:WBGene00200392 K01A6.19 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200393 C04C11.16 No description available WB:WBGene00200394 C38C5.3 No description available WB:WBGene00200395 F11D5.26 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200396 ZK84.14 Enriched in sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200397 ZK632.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200398 C33F10.22 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200399 F26A10.23 Is affected by adr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200400 C16E9.21 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200401 C02B4.13 No description available WB:WBGene00200402 2L52.2 No description available WB:WBGene00200403 K07E12.5 No description available WB:WBGene00200404 F16H6.12 No description available WB:WBGene00200405 ZK617.20 No description available WB:WBGene00200406 C04H5.10 No description available WB:WBGene00200407 C14F11.26 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 and camt-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200408 ZC123.8 No description available WB:WBGene00200409 C55H1.4 No description available WB:WBGene00200410 C14F11.27 No description available WB:WBGene00200411 F08F1.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00200412 W01C8.14 No description available WB:WBGene00200413 C48D5.8 Is affected by ifo-1 based on microarray studies. WB:WBGene00200414 C43D7.16 No description available WB:WBGene00200415 B0244.14 No description available WB:WBGene00200416 C33D12.14 No description available WB:WBGene00200417 F56A6.6 No description available WB:WBGene00200418 C05H8.4 No description available WB:WBGene00200419 K08F8.14 No description available WB:WBGene00200420 Y15E3A.11 No description available WB:WBGene00200421 T06F4.15 No description available WB:WBGene00200422 Y95B8A.15 No description available WB:WBGene00200423 T11F9.27 Enriched in head mesodermal cell and neurons based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00200424 H19M22.9 No description available WB:WBGene00200425 T27F7.9 No description available WB:WBGene00200426 C43H6.10 No description available WB:WBGene00200427 W06D4.9 No description available WB:WBGene00200428 C16C2.8 No description available WB:WBGene00200429 C42D4.17 No description available WB:WBGene00200430 W08D2.12 Enriched in AFD based on RNA-seq studies. Is affected by dlc-1 and mrps-5 based on RNA-seq studies. WB:WBGene00200431 K09G1.6 No description available WB:WBGene00200432 C13A10.5 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200433 K03H4.6 Is affected by dlc-1 and set-2 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00200434 Y56A3A.39 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200435 R10H1.8 No description available WB:WBGene00200436 C34B4.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00200437 K05B2.8 No description available WB:WBGene00200438 F10E9.17 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00200439 C09H10.16 Enriched in sensory neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00200440 F55F3.7 Enriched in neurons based on RNA-seq studies. Is affected by prg-1 based on RNA-seq studies. WB:WBGene00200441 DY3.10 No description available WB:WBGene00200442 Y54E10A.26 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; daf-2; and pmt-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200443 C11H1.10 No description available WB:WBGene00200444 C15B12.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00200445 Y105C5A.1278 Is affected by tdp-1 based on RNA-seq studies. WB:WBGene00200446 Y51H7C.31 No description available WB:WBGene00200447 C05E11.15 Is affected by several genes including fbf-1; ins-11; and klf-1 based on RNA-seq studies. WB:WBGene00200448 Y38F2AR.20 No description available WB:WBGene00200449 H32C10.98 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00200450 C04C11.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00200451 H08J11.10 No description available WB:WBGene00200452 F46G11.17 No description available WB:WBGene00200453 C16E9.22 No description available WB:WBGene00200454 F47A4.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00200455 R151.18 No description available WB:WBGene00200456 T12B3.9 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; spr-5; and ins-11 based on RNA-seq and microarray studies. WB:WBGene00200457 Y105C5A.1279 Is affected by daf-2 and adr-1 based on microarray and RNA-seq studies. WB:WBGene00200458 F11A1.13 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00200459 F38H4.15 Is affected by several genes including cep-1; dlc-1; and etr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00200460 B0212.7 No description available WB:WBGene00200461 C18F3.9 No description available WB:WBGene00200462 B0310.9 No description available WB:WBGene00200463 T13H10.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200464 T22B7.17 No description available WB:WBGene00200465 C44B12.11 No description available WB:WBGene00200466 Y59A8B.33 No description available WB:WBGene00200467 W09D6.10 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00200468 F20B10.9 No description available WB:WBGene00200469 F13A2.12 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00200470 Y54G9A.16 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00200471 K04D7.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00200472 H03A11.10 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200473 R12G8.4 No description available WB:WBGene00200474 W01A11.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200475 F29A7.9 Is affected by eat-2 based on microarray studies. WB:WBGene00200476 C48D5.9 Enriched in AVK; neurons; and sensory neurons based on RNA-seq studies. Is affected by bcat-1 and camt-1 based on RNA-seq studies. WB:WBGene00200477 Y47D3B.21 Enriched in neurons based on RNA-seq studies. WB:WBGene00200478 Y73B6BL.282 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200479 F15A8.13 Is affected by pmt-2 based on microarray studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00200480 B0310.10 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00200481 T14B1.5 No description available WB:WBGene00200482 F11A6.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00200483 Y32F6B.7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00200484 T09E11.14 No description available WB:WBGene00200485 ZK757.7 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and alg-1 based on RNA-seq studies. WB:WBGene00200486 C02C6.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00200487 K08A8.23 Enriched in AVK based on RNA-seq studies. Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00200488 C16B8.9 Is affected by pmt-2 and spr-5 based on microarray and RNA-seq studies. WB:WBGene00200489 K08B5.7 No description available WB:WBGene00200490 C08B6.17 Is affected by several genes including set-2; hmg-4; and hmg-3 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00200491 T06F4.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200492 ZK563.9 No description available WB:WBGene00200493 K03H9.12 Is affected by daf-2 based on microarray studies. WB:WBGene00200494 D2089.7 Enriched in AVK based on RNA-seq studies. WB:WBGene00200495 T05A6.17 No description available WB:WBGene00200496 Y53C10A.21 No description available WB:WBGene00200497 F22E12.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200498 F46C8.19 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00200499 F10C1.17 Is affected by daf-2 based on microarray studies. WB:WBGene00200500 T21B10.12 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200501 R08B4.13 No description available WB:WBGene00200502 C54D2.14 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00200503 F29G9.14 Is affected by several genes including sek-1; pgl-1; and alg-1 based on RNA-seq and microarray studies. Is affected by four chemicals including 4-bromodiphenyl ether; Cry5B; and glycine based on microarray and RNA-seq studies. WB:WBGene00200504 T21H8.9 Enriched in neurons based on RNA-seq studies. Is affected by alg-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200505 C35A11.10 No description available WB:WBGene00200506 ZC123.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00200507 C03C11.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00200508 F14F11.5 No description available WB:WBGene00200509 Y16B4A.3 Is affected by daf-2 based on microarray studies. WB:WBGene00200510 F40E3.9 No description available WB:WBGene00200511 R04B3.7 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200512 Y51A2B.15 No description available WB:WBGene00200513 C11E4.12 Is affected by adr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200514 R07G3.14 No description available WB:WBGene00200515 R02F11.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200516 C47G2.17 No description available WB:WBGene00200517 W04G5.15 Is affected by eat-2 based on microarray studies. WB:WBGene00200518 F38B6.17 Enriched in cholinergic neurons based on single-cell RNA-seq studies. WB:WBGene00200519 F13G3.14 Is affected by cep-1 and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00200520 C13D9.13 No description available WB:WBGene00200521 T09B4.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200522 R04F11.23 No description available WB:WBGene00200523 Y75B8A.56 No description available WB:WBGene00200524 F22B7.14 Is affected by emr-1 based on RNA-seq studies. WB:WBGene00200525 R07H5.13 No description available WB:WBGene00200526 C05B10.17 No description available WB:WBGene00200527 T10C6.19 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00200528 R09G11.3 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00200529 ZC53.15 No description available WB:WBGene00200530 C16B8.10 Is affected by cep-1 and hmg-3 based on RNA-seq studies. WB:WBGene00200531 C43F9.18 No description available WB:WBGene00200532 K08E7.12 No description available WB:WBGene00200533 T11A5.10 No description available WB:WBGene00200534 H13N06.10 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00200535 F56F10.9 No description available WB:WBGene00200536 C04C11.18 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200537 R11B5.10 No description available WB:WBGene00200538 C08F8.13 No description available WB:WBGene00200539 ZK638.1 Is affected by daf-2 based on microarray studies. WB:WBGene00200540 F46F3.15 No description available WB:WBGene00200541 ZK180.15 No description available WB:WBGene00200542 T06E8.7 No description available WB:WBGene00200543 C34E7.8 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200544 F28F5.15 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200545 K01A12.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00200546 C09B7.9 No description available WB:WBGene00200547 F49E10.21 No description available WB:WBGene00200548 F47C8.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00200549 H03E18.6 No description available WB:WBGene00200550 B0207.16 No description available WB:WBGene00200551 C04C11.19 No description available WB:WBGene00200552 C03A3.6 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00200553 C02B10.74 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200554 H08J11.11 No description available WB:WBGene00200555 R153.5 Enriched in head mesodermal cell and sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200556 C54G4.14 No description available WB:WBGene00200557 F35D2.14 Is affected by daf-2 based on microarray studies. WB:WBGene00200558 W02B8.12 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00200559 ZK180.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00200560 Y43H11AL.6 Is affected by tdp-1 based on RNA-seq studies. WB:WBGene00200561 C10C6.11 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200562 F13B9.10 Is affected by alg-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200563 F56E3.18 No description available WB:WBGene00200564 W01G7.6 No description available WB:WBGene00200565 F26D10.22 No description available WB:WBGene00200566 F10E9.18 Enriched in sensory neurons based on RNA-seq studies. Is affected by nfki-1 and camt-1 based on RNA-seq studies. WB:WBGene00200567 K11G9.13 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00200568 C29F7.9 No description available WB:WBGene00200569 Y49G5B.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200570 F25B4.15 No description available WB:WBGene00200571 ZK1025.18 No description available WB:WBGene00200572 T21H3.9 No description available WB:WBGene00200573 W06H8.14 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200574 F20B10.10 Enriched in neurons based on RNA-seq studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00200575 F44E7.15 Is affected by adr-1; meg-3; and meg-4 based on RNA-seq studies. WB:WBGene00200576 F53B1.13 Is affected by several genes including daf-2; cep-1; and met-2 based on RNA-seq and microarray studies. WB:WBGene00200577 Y65B4BL.12 Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00200578 T21B6.14 Is affected by daf-2 based on microarray studies. WB:WBGene00200579 B0034.15 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00200580 C28G1.7 Is affected by daf-2 based on microarray studies. WB:WBGene00200581 F58H1.24 No description available WB:WBGene00200582 K12G11.12 Is affected by etr-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00200583 F17H10.8 No description available WB:WBGene00200584 B0334.19 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00200585 T26H10.8 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200586 C09D8.12 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200587 C18A3.22 No description available WB:WBGene00200588 M60.13 Is affected by cep-1; hmg-3; and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00200589 ZC504.16 No description available WB:WBGene00200590 T05B11.11 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00200591 F47F2.6 No description available WB:WBGene00200592 Y40B10B.3 No description available WB:WBGene00200593 F41E7.16 No description available WB:WBGene00200594 B0350.76 Enriched in NSM based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and hpl-2 based on RNA-seq studies. WB:WBGene00200595 C37E2.7 Is affected by daf-2 based on microarray studies. WB:WBGene00200596 C01B7.15 No description available WB:WBGene00200597 F38B6.18 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200598 C07G2.4 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00200599 F45G2.12 No description available WB:WBGene00200600 C08G9.9 No description available WB:WBGene00200601 M117.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200602 C24A1.6 No description available WB:WBGene00200603 ZK970.11 No description available WB:WBGene00200604 F32A6.12 No description available WB:WBGene00200605 F35G2.16 Is affected by several genes including daf-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00200606 Y37E3.29 No description available WB:WBGene00200607 Y54G2A.67 Is affected by pmt-2 based on microarray studies. WB:WBGene00200608 Y39G10AL.5 No description available WB:WBGene00200609 Y97E10B.13 No description available WB:WBGene00200610 C44C11.5 No description available WB:WBGene00200611 C33G3.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00200612 Y46G5A.45 Is affected by eat-2 based on microarray studies. WB:WBGene00200613 C08C3.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200614 Y57G11C.1139 No description available WB:WBGene00200615 M01E10.4 No description available WB:WBGene00200616 F56B3.15 Is affected by swsn-1 based on RNA-seq studies. WB:WBGene00200617 B0495.21 No description available WB:WBGene00200618 ZK809.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200619 F01E11.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00200620 T22B2.10 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00200621 F22B3.18 No description available WB:WBGene00200622 F46F3.16 No description available WB:WBGene00200623 T24A11.9 No description available WB:WBGene00200624 F10F2.14 No description available WB:WBGene00200625 F54E4.14 Is affected by daf-2 based on microarray studies. WB:WBGene00200626 C45B2.16 No description available WB:WBGene00200627 K08B12.12 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00200628 T22B7.18 No description available WB:WBGene00200629 F49E12.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00200630 C06A6.14 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00200631 C02B8.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200632 F37B12.13 No description available WB:WBGene00200633 C46G7.109 No description available WB:WBGene00200634 T09B4.18 No description available WB:WBGene00200635 ZK381.54 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200636 ZC53.16 Is affected by eat-2 based on microarray studies. WB:WBGene00200637 K01A2.15 Is affected by set-2 based on RNA-seq studies. WB:WBGene00200638 H39E23.4 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200639 ZK381.55 Enriched in neurons based on RNA-seq studies. WB:WBGene00200640 Y41D4B.30 No description available WB:WBGene00200641 T24F3.1 No description available WB:WBGene00200642 T21B6.15 No description available WB:WBGene00200643 F29G9.15 No description available WB:WBGene00200644 ZK973.23 No description available WB:WBGene00200645 R03E9.9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200646 C35C5.20 No description available WB:WBGene00200647 E02A10.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00200648 T21G5.10 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00200649 ZK180.17 No description available WB:WBGene00200650 T12A7.12 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200651 ZC477.18 No description available WB:WBGene00200652 C16H3.6 Is affected by pmt-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200653 Y51H7BR.11 No description available WB:WBGene00200654 F27C1.17 No description available WB:WBGene00200655 K09H11.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00200656 C17D12.15 Is affected by Tunicamycin based on microarray studies. WB:WBGene00200657 C29E6.15 No description available WB:WBGene00200658 C14F5.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200659 F10D2.15 Is affected by etr-1 based on RNA-seq studies. Is affected by Ethanol and multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00200660 W10G11.23 No description available WB:WBGene00200661 C17D12.16 No description available WB:WBGene00200662 F12F6.17 Is affected by several genes including lin-29; set-2; and emr-1 based on RNA-seq studies. WB:WBGene00200663 R08E3.9 No description available WB:WBGene00200664 F25B4.16 Enriched in neurons based on RNA-seq studies. Is affected by rnp-6 based on RNA-seq studies. WB:WBGene00200665 Y34B4A.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200666 T01C3.13 Is affected by daf-2 based on microarray studies. WB:WBGene00200667 F56A12.9 Is affected by cep-1 and spt-16 based on RNA-seq studies. WB:WBGene00200668 ZK39.12 Enriched in neurons based on RNA-seq studies. Is affected by alg-1 and mrps-5 based on RNA-seq studies. WB:WBGene00200669 B0025.6 No description available WB:WBGene00200670 F08C6.14 No description available WB:WBGene00200671 F58E6.16 No description available WB:WBGene00200672 R06C7.12 No description available WB:WBGene00200673 ZK994.11 No description available WB:WBGene00200674 T24D11.6 No description available WB:WBGene00200675 E01G6.8 No description available WB:WBGene00200676 Y59A8B.34 No description available WB:WBGene00200677 C55A6.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200678 K07H8.16 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00200679 R07D5.8 Enriched in sensory neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00200680 F55D10.8 No description available WB:WBGene00200681 Y38F2AL.10 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00200682 W07G1.18 No description available WB:WBGene00200683 C09G5.11 No description available WB:WBGene00200684 F25H8.21 Expressed in amphid sheath cell; excretory duct; and phasmid socket cell. WB:WBGene00200685 D2023.17 Is affected by cep-1 and hlh-26 based on RNA-seq studies. WB:WBGene00200686 R11D1.14 No description available WB:WBGene00200687 C31G12.14 No description available WB:WBGene00200688 C36F7.21 Is affected by daf-2 based on microarray studies. WB:WBGene00200689 F35G2.17 No description available WB:WBGene00200690 C34E11.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200691 F46C8.20 No description available WB:WBGene00200692 H03A11.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200693 ZK1025.19 No description available WB:WBGene00200694 F18E9.11 No description available WB:WBGene00200695 H14N18.7 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200696 C17H11.9 No description available WB:WBGene00200697 C41H7.10 No description available WB:WBGene00200698 F11D5.27 Is affected by daf-2 based on microarray studies. WB:WBGene00200699 K10D6.17 Is affected by chd-3 and let-418 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00200700 F08B6.6 Is affected by adr-1 and camt-1 based on RNA-seq studies. WB:WBGene00200701 C05B10.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200702 C16A3.15 Is affected by ifo-1 based on microarray studies. WB:WBGene00200703 Y51H7C.32 No description available WB:WBGene00200704 ZC21.14 No description available WB:WBGene00200705 Y71A12B.30 No description available WB:WBGene00200706 K08E4.12 Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00200707 Y71G12B.37 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00200708 K11H3.12 No description available WB:WBGene00200709 Y49E10.32 No description available WB:WBGene00200710 CD4.15 Enriched in neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00200711 C54D2.15 Is affected by several genes including hpl-2; lem-2; and emr-1 based on RNA-seq studies. WB:WBGene00200712 H24G06.3 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00200713 T07F10.11 Is affected by met-2 and etr-1 based on RNA-seq studies. WB:WBGene00200714 ZK836.17 Is affected by daf-2 and ifo-1 based on microarray studies. WB:WBGene00200715 K04F10.8 Is affected by several genes including pgl-1; cep-1; and sod-2 based on RNA-seq studies. Is affected by rotenone based on RNA-seq studies. WB:WBGene00200716 C18F3.10 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200717 F11C1.15 No description available WB:WBGene00200718 F55G7.6 No description available WB:WBGene00200719 K11C4.10 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00200720 C37A5.14 No description available WB:WBGene00200721 C16E9.23 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200722 F47B7.15 No description available WB:WBGene00200723 T23E1.6 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dlc-1 and pmt-2 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200724 F32G8.12 No description available WB:WBGene00200725 Y39A3CL.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200726 Y71F9AR.7 No description available WB:WBGene00200727 F25H8.22 Is affected by daf-2 based on microarray studies. WB:WBGene00200728 F45B8.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200729 C02H7.5 No description available WB:WBGene00200730 C08G9.10 No description available WB:WBGene00200731 F48C11.8 No description available WB:WBGene00200732 BE0003N10.5 No description available WB:WBGene00200733 C34F11.16 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00200734 C29A12.18 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200735 C26G2.9 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00200736 C18A3.23 No description available WB:WBGene00200737 Y40C5A.21 No description available WB:WBGene00200738 F45B8.19 No description available WB:WBGene00200739 K02D3.4 Is affected by daf-2 and ifo-1 based on microarray studies. WB:WBGene00200740 Y47C4A.3 Enriched in neurons based on RNA-seq studies. WB:WBGene00200741 B0403.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00200742 K02A11.10 No description available WB:WBGene00200743 C05A2.2 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200744 T22B2.11 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00200745 F15B9.14 No description available WB:WBGene00200746 C27H6.10 No description available WB:WBGene00200747 F52B10.19 Is affected by cep-1; adr-1; and ifo-1 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200748 E02C12.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200749 F38A3.5 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00200750 F20D1.19 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200751 B0478.25 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200752 ZK697.16 No description available WB:WBGene00200753 F48D6.5 No description available WB:WBGene00200754 F45D3.12 No description available WB:WBGene00200755 F08G5.18 No description available WB:WBGene00200756 H01A20.4 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200757 D1046.15 Enriched in sensory neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00200758 F35B12.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00200759 F11D11.20 No description available WB:WBGene00200760 Y26D4A.24 Enriched in neurons based on RNA-seq studies. Is affected by spr-5 based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00200761 C02D4.14 Is affected by daf-2 based on microarray studies. WB:WBGene00200762 T28B11.19 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00200763 Y37B11A.5 No description available WB:WBGene00200764 W07G1.19 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00200765 C25H3.19 No description available WB:WBGene00200766 F09C3.9 No description available WB:WBGene00200767 Y71H9A.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00200768 Y23H5A.11 Is affected by eat-2 and set-2 based on microarray and RNA-seq studies. WB:WBGene00200769 T28D6.14 No description available WB:WBGene00200770 W06A7.10 No description available WB:WBGene00200771 C18D1.18 Is affected by daf-2 based on microarray studies. WB:WBGene00200772 K07C5.16 No description available WB:WBGene00200773 T10E9.13 No description available WB:WBGene00200774 W02B12.18 Is affected by daf-2 based on microarray studies. WB:WBGene00200775 F57C7.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200776 F40G9.22 No description available WB:WBGene00200777 C39D10.15 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00200778 T10H10.6 No description available WB:WBGene00200779 F56A11.12 Is affected by tdp-1 based on RNA-seq studies. WB:WBGene00200780 C05E11.16 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00200781 C53B7.11 Is affected by eat-2 based on microarray studies. WB:WBGene00200782 C39B10.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00200783 T14F9.18 Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200784 K06A1.9 Enriched in neurons based on RNA-seq studies. Is affected by ifo-1 based on microarray studies. WB:WBGene00200785 C49A9.39 Is affected by tdp-1 based on RNA-seq studies. WB:WBGene00200786 H36N01.4 No description available WB:WBGene00200787 T12A2.20 No description available WB:WBGene00200788 ZK643.11 Is affected by daf-2 based on microarray studies. WB:WBGene00200789 C44E12.8 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200790 C45G7.11 No description available WB:WBGene00200791 M7.14 No description available WB:WBGene00200792 C34H3.20 Is affected by daf-2 based on microarray studies. WB:WBGene00200793 F46F3.17 No description available WB:WBGene00200794 F15G9.8 No description available WB:WBGene00200795 C08B11.12 Is affected by adr-1 and dlc-1 based on RNA-seq studies. WB:WBGene00200796 H22K11.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00200797 Y7A5A.18 No description available WB:WBGene00200798 F26D11.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00200799 F44D12.18 No description available WB:WBGene00200800 K02B2.37 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00200801 F09D5.8 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200802 F40H3.15 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200803 K03H9.13 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200804 T27F7.10 Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00200805 F57F4.7 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00200806 E01G6.9 Is affected by Cry5B; silicon dioxide nanoparticle; and Oligosaccharides based on microarray studies. WB:WBGene00200807 F40B5.7 No description available WB:WBGene00200808 B0034.16 Is affected by set-2 based on RNA-seq studies. WB:WBGene00200809 T04C12.28 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; cep-1; and fzo-1 based on RNA-seq and microarray studies. WB:WBGene00200810 Y53H1C.9 No description available WB:WBGene00200811 C06B8.15 No description available WB:WBGene00200812 C17C3.23 Is affected by daf-2 based on microarray studies. WB:WBGene00200813 C01B9.6 No description available WB:WBGene00200814 F28F9.14 Enriched in neurons based on RNA-seq studies. Is affected by alh-4 based on RNA-seq studies. WB:WBGene00200815 D1044.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00200816 Y42H9B.8 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00200817 F44E5.12 No description available WB:WBGene00200818 F31E8.18 Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00200819 ZK381.56 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00200820 Y50D7A.17 No description available WB:WBGene00200821 T12C9.8 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00200822 F09F3.17 Is affected by vit-5 based on RNA-seq studies. WB:WBGene00200823 Y54G2A.68 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00200824 F08C6.15 No description available WB:WBGene00200825 C25F6.23 Enriched in AFD based on RNA-seq studies. WB:WBGene00200826 W06B11.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200827 F08H9.14 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00200828 F13D11.17 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200829 F43D9.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00200830 T28B11.20 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq and microarray studies. WB:WBGene00200831 C41G11.16 No description available WB:WBGene00200832 T13A10.62 No description available WB:WBGene00200833 D2092.14 No description available WB:WBGene00200834 K02E2.15 Is affected by pmt-2 based on microarray studies. WB:WBGene00200835 H32C10.99 No description available WB:WBGene00200836 C25F9.17 Is affected by pmt-2 based on microarray studies. WB:WBGene00200837 R04F11.24 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00200838 ZK596.4 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00200839 F53B3.11 Is affected by cep-1 and set-2 based on RNA-seq studies. WB:WBGene00200840 R13H8.4 No description available WB:WBGene00200841 C24H11.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00200842 C50C3.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00200843 C07H4.4 No description available WB:WBGene00200844 F09G8.11 No description available WB:WBGene00200845 ZC373.8 Is affected by dpy-21 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00200846 F19C6.11 No description available WB:WBGene00200847 T16A9.6 Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. Is affected by Ethanol; Tunicamycin; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00200848 Y51H7C.33 No description available WB:WBGene00200849 R53.11 No description available WB:WBGene00200850 C18H7.16 No description available WB:WBGene00200851 D2045.10 No description available WB:WBGene00200852 E01G6.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00200853 C29H12.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200854 C01H6.10 No description available WB:WBGene00200855 cTel52S.1 No description available WB:WBGene00200856 Y75B8A.57 No description available WB:WBGene00200857 ZK470.12 No description available WB:WBGene00200858 F28C1.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200859 K10D6.18 Is affected by Tunicamycin based on microarray studies. WB:WBGene00200860 F54A5.5 No description available WB:WBGene00200861 F28A12.6 No description available WB:WBGene00200862 R02D5.20 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and pgrn-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200863 Y69E1A.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200864 Y59A8B.35 No description available WB:WBGene00200865 F28F9.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00200866 F47E1.14 No description available WB:WBGene00200867 C04A2.10 Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00200868 F26D12.100 No description available WB:WBGene00200869 F09E8.11 No description available WB:WBGene00200870 F42G4.10 Is affected by lem-2; emr-1; and cep-1 based on RNA-seq studies. WB:WBGene00200871 C09B9.83 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200872 W03G11.19 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00200873 Y53F4B.61 No description available WB:WBGene00200874 C04A2.11 Is affected by daf-2 based on microarray studies. WB:WBGene00200875 C13C4.10 No description available WB:WBGene00200876 C16C8.24 No description available WB:WBGene00200877 F39B1.4 Is affected by pmt-2 based on microarray studies. WB:WBGene00200878 Y47G6A.35 Enriched in AFD; ASER; and PLM based on RNA-seq studies. WB:WBGene00200879 C52E4.18 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00200880 ZK377.11 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00200881 Y73B6BL.283 No description available WB:WBGene00200882 R09A8.7 No description available WB:WBGene00200883 F45D3.13 No description available WB:WBGene00200884 F25D1.10 Is affected by cep-1 and hlh-26 based on RNA-seq studies. WB:WBGene00200885 T21B4.19 No description available WB:WBGene00200886 F22F7.10 No description available WB:WBGene00200887 Y51H7C.34 No description available WB:WBGene00200888 R05D7.9 No description available WB:WBGene00200889 K03C7.13 No description available WB:WBGene00200890 C50B8.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200891 F25H10.8 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00200892 Y43F8B.26 Is affected by spt-16 based on RNA-seq studies. WB:WBGene00200893 F52D10.12 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200894 C28A5.12 No description available WB:WBGene00200895 C29H12.12 No description available WB:WBGene00200896 F42H10.15 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00200897 B0491.11 No description available WB:WBGene00200898 B0350.77 No description available WB:WBGene00200899 F14D12.12 No description available WB:WBGene00200900 F10D11.7 No description available WB:WBGene00200901 ZK899.11 No description available WB:WBGene00200902 Y119D3B.27 No description available WB:WBGene00200903 K04C2.10 Is affected by eat-2 based on microarray studies. WB:WBGene00200904 F54G8.8 Is affected by daf-2 based on microarray studies. WB:WBGene00200905 F59F5.9 No description available WB:WBGene00200906 F15A8.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200907 W09C2.11 No description available WB:WBGene00200908 K07F5.20 Is affected by pmt-2 based on microarray studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00200909 H08J11.12 Is affected by ifo-1 based on microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00200910 F11A6.12 No description available WB:WBGene00200911 Y37A1B.336 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00200912 T04F3.11 Is affected by daf-2 based on microarray studies. WB:WBGene00200913 F56F3.12 No description available WB:WBGene00200914 F22B7.15 No description available WB:WBGene00200915 ZK525.8 Is affected by Tunicamycin based on microarray studies. WB:WBGene00200916 F46F3.18 Is affected by chd-3; let-418; and dlc-1 based on RNA-seq studies. WB:WBGene00200917 Y70C5A.5 No description available WB:WBGene00200918 T09A12.6 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00200919 T04C9.11 Enriched in neurons based on RNA-seq studies. Is affected by smg-2 based on RNA-seq studies. WB:WBGene00200920 F29F11.15 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; dpy-21; and mrps-5 based on RNA-seq studies. WB:WBGene00200921 F45D3.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200922 T07F10.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200923 W05E10.17 No description available WB:WBGene00200924 F35C12.5 Enriched in AFD and ASER based on RNA-seq studies. WB:WBGene00200925 H13N06.11 No description available WB:WBGene00200926 K11C4.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00200927 Y116A8C.466 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200928 K10C2.11 No description available WB:WBGene00200929 T06E4.18 Enriched in neurons based on RNA-seq studies. Is affected by zip-3 and jmjd-5 based on RNA-seq studies. WB:WBGene00200930 F17E5.5 Is affected by Tunicamycin based on microarray studies. WB:WBGene00200931 W07G4.11 No description available WB:WBGene00200932 F53B7.13 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00200933 C42D8.18 No description available WB:WBGene00200934 C48A7.14 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00200935 F56E3.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00200936 T07D10.11 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200937 F57C7.13 No description available WB:WBGene00200938 K07E12.6 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00200939 F10F2.15 No description available WB:WBGene00200940 K08F4.14 No description available WB:WBGene00200941 T25C12.9 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00200942 R10E12.9 No description available WB:WBGene00200943 F58F6.10 No description available WB:WBGene00200944 ZK836.18 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00200945 Y48C3A.23 No description available WB:WBGene00200946 T05B9.3 Enriched in AVK based on RNA-seq studies. WB:WBGene00200947 F57F10.5 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00200948 Y42H9B.9 Is affected by cep-1; chd-3; and let-418 based on RNA-seq studies. WB:WBGene00200949 C40C9.15 No description available WB:WBGene00200950 T06H11.19 No description available WB:WBGene00200951 R13H4.12 No description available WB:WBGene00200952 C27C12.9 No description available WB:WBGene00200953 T22C1.15 Is affected by several genes including daf-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00200954 C37E2.8 Is affected by daf-2 based on microarray studies. WB:WBGene00200955 B0454.21 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00200956 C15C7.11 No description available WB:WBGene00200957 T02G6.12 Is affected by daf-2 based on RNA-seq studies. WB:WBGene00200958 C11G10.13 No description available WB:WBGene00200959 C14F11.28 Is affected by Tunicamycin and Oligosaccharides based on microarray studies. WB:WBGene00200960 R10E11.12 Is affected by adr-1 and mrps-5 based on RNA-seq studies. WB:WBGene00200961 F26A10.24 No description available WB:WBGene00200962 C01B10.46 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200963 C01B12.10 Is affected by daf-2 based on microarray studies. WB:WBGene00200964 Y97E10B.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200965 C45B2.17 No description available WB:WBGene00200966 R13A1.16 Is affected by set-2 based on RNA-seq studies. WB:WBGene00200967 C13C4.11 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00200968 B0001.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200969 B0273.113 No description available WB:WBGene00200970 F17B5.11 No description available WB:WBGene00200971 T01B10.13 Is affected by cep-1; dlc-1; and camt-1 based on RNA-seq studies. WB:WBGene00200972 T22B7.19 Is affected by cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00200973 F25F2.5 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00200974 W04E12.12 No description available WB:WBGene00200975 T13H10.16 Is affected by daf-12 based on RNA-seq studies. WB:WBGene00200976 K10D6.19 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200977 T28B4.13 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00200978 M6.10 No description available WB:WBGene00200979 K10D6.20 No description available WB:WBGene00200980 K03B8.22 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200981 F35E12.12 Is affected by cep-1; spt-16; and set-2 based on RNA-seq studies. WB:WBGene00200982 C06E7.92 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00200983 W01H2.9 No description available WB:WBGene00200984 F07A11.13 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00200985 W04A4.8 No description available WB:WBGene00200986 C15C8.11 Is affected by daf-2 based on microarray studies. WB:WBGene00200987 F46A9.10 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200988 C40H5.16 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00200989 ZK682.12 Is affected by emr-1 and lem-2 based on RNA-seq studies. WB:WBGene00200990 F12D9.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00200991 C26E6.14 No description available WB:WBGene00200992 C09D1.5 No description available WB:WBGene00200993 C32A9.4 No description available WB:WBGene00200994 F32B5.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00200995 F57G12.11 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00200996 ZK675.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00200997 C52E12.9 No description available WB:WBGene00200998 ZK662.8 Is affected by several genes including daf-2; cep-1; and set-2 based on RNA-seq and microarray studies. WB:WBGene00200999 Y34B4A.17 No description available WB:WBGene00201000 ZC53.17 No description available WB:WBGene00201001 F11H8.8 Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00201002 T28B11.21 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201003 C25B8.11 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00201004 R193.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00201005 M04B2.11 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00201006 C56E10.6 No description available WB:WBGene00201007 Y80E2A.2 Enriched in neurons based on RNA-seq studies. WB:WBGene00201008 R173.11 No description available WB:WBGene00201009 W03G11.20 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00201010 T27A10.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201011 F35E8.20 No description available WB:WBGene00201012 T04C12.29 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00201013 Y87G2A.23 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00201014 T19A5.12 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00201015 T12G3.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201016 T09F5.18 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00201017 F08A8.10 No description available WB:WBGene00201018 F56C11.7 No description available WB:WBGene00201019 Y71F9B.22 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00201020 K04A8.16 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00201021 Y47D3B.22 Is affected by pmt-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00201022 Y69A2AR.43 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201023 F07C6.7 No description available WB:WBGene00201024 C53C9.5 No description available WB:WBGene00201025 R186.13 No description available WB:WBGene00201026 T24B8.20 No description available WB:WBGene00201027 K12F2.5 No description available WB:WBGene00201028 T03G6.6 No description available WB:WBGene00201029 Y39G8C.11 No description available WB:WBGene00201030 C06E7.93 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201031 ZK792.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201032 Y39D8B.5 No description available WB:WBGene00201033 B0395.9 No description available WB:WBGene00201034 F57B7.12 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by daf-2 and lpd-3 based on microarray and RNA-seq studies. WB:WBGene00201035 C52G5.9 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. Is affected by Cry5B based on microarray studies. WB:WBGene00201036 M03E7.8 No description available WB:WBGene00201037 R08E3.10 No description available WB:WBGene00201038 Y41G9A.15 No description available WB:WBGene00201039 F40E10.13 No description available WB:WBGene00201040 C30D11.4 No description available WB:WBGene00201041 T28C12.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00201042 T02C5.7 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201043 F16H11.6 Is affected by set-2 based on RNA-seq studies. WB:WBGene00201044 R12H7.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201045 ZK867.19 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201046 Y67D2.8 Enriched in AFD and ASER based on RNA-seq studies. Is affected by daf-16 based on RNA-seq studies. WB:WBGene00201047 F43C9.7 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201048 F09G8.12 No description available WB:WBGene00201049 T05B4.19 Is affected by daf-2 based on microarray studies. WB:WBGene00201050 F41D9.13 No description available WB:WBGene00201051 Y47D3B.23 No description available WB:WBGene00201052 R09E10.14 No description available WB:WBGene00201053 B0454.22 No description available WB:WBGene00201054 C29A12.19 No description available WB:WBGene00201055 C29A12.20 Enriched in neurons based on RNA-seq studies. WB:WBGene00201056 C34D1.13 No description available WB:WBGene00201057 F08G5.19 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00201058 C06H2.10 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00201059 cTel7X.3 No description available WB:WBGene00201060 K10G6.7 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201061 F54D12.19 No description available WB:WBGene00201062 C54G10.5 No description available WB:WBGene00201063 T06D8.15 No description available WB:WBGene00201064 B0302.7 Is affected by adr-1; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00201065 C34D10.4 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201066 F29F11.16 No description available WB:WBGene00201067 W07G1.20 No description available WB:WBGene00201068 C49A1.17 No description available WB:WBGene00201069 F22A3.16 No description available WB:WBGene00201070 F25H10.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; daf-2; and hlh-26 based on RNA-seq and microarray studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00201071 C28F5.6 No description available WB:WBGene00201072 F32B6.14 Enriched in neurons based on RNA-seq studies. Is affected by daf-12; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00201073 F54H5.9 Is affected by cep-1 and mrps-5 based on RNA-seq studies. WB:WBGene00201074 F54H5.10 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00201075 F25D7.9 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00201076 F35G2.18 No description available WB:WBGene00201077 T10B10.14 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00201078 C49F8.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201079 K04B12.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00201080 F57G12.12 No description available WB:WBGene00201081 K02H8.5 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201082 F47C8.7 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by procyanidin and Oligosaccharides based on microarray studies. WB:WBGene00201083 F59D12.13 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00201084 T23D8.10 No description available WB:WBGene00201085 R04F11.25 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201086 Y102A11A.14 Is affected by set-2 based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00201087 T07F12.10 No description available WB:WBGene00201088 R11G1.9 No description available WB:WBGene00201089 Y40C7B.8 No description available WB:WBGene00201090 ZC21.15 No description available WB:WBGene00201091 Y40C5A.22 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00201092 F48B9.11 No description available WB:WBGene00201093 Y46E12BL.9 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. Is affected by glycine and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00201094 W04D2.12 No description available WB:WBGene00201095 F15A2.12 No description available WB:WBGene00201096 F56F4.11 Is affected by pmt-2 based on microarray studies. WB:WBGene00201097 F19G12.13 Is affected by hmg-3; daf-2; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00201098 T21C9.16 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00201099 K02E10.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00201100 C32D5.19 No description available WB:WBGene00201101 Y105E8A.47 Enriched in neurons based on RNA-seq studies. WB:WBGene00201102 C40H1.12 Is affected by iron oxide nanoparticle and Tunicamycin based on microarray studies. WB:WBGene00201103 C01C4.6 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00201104 ZC247.6 No description available WB:WBGene00201105 C24H12.14 No description available WB:WBGene00201106 F48C1.14 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00201107 C36F7.22 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201108 B0350.78 Enriched in AVK based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00201109 C46G7.110 No description available WB:WBGene00201110 T21B6.16 Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201111 C36E8.10 Is affected by several genes including eat-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. WB:WBGene00201112 W01C8.15 Is affected by let-418 based on RNA-seq studies. WB:WBGene00201113 T06F4.17 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and set-2 based on RNA-seq studies. WB:WBGene00201114 C01B10.47 Is affected by lem-2; emr-1; and eat-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201115 C05C9.13 No description available WB:WBGene00201116 C16E9.24 Enriched in neurons based on RNA-seq studies. WB:WBGene00201117 C06A8.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00201118 R09H10.11 No description available WB:WBGene00201119 W01A11.15 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00201120 R07B1.22 Enriched in neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00201121 T01H3.9 Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00201122 B0454.23 No description available WB:WBGene00201123 Y42A5A.12 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201124 F40E10.14 Is affected by set-2 and etr-1 based on RNA-seq studies. WB:WBGene00201125 F17A9.7 Is affected by several genes including set-2; smg-2; and adr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00201126 C15C7.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201127 K02A6.5 No description available WB:WBGene00201128 C34G6.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201129 M02F4.11 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201130 K10D6.21 Enriched in neurons based on RNA-seq studies. WB:WBGene00201131 R153.6 No description available WB:WBGene00201132 C45B2.18 Is affected by let-418 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201133 F35G2.19 Is affected by dlc-1; etr-1; and hlh-26 based on RNA-seq studies. WB:WBGene00201134 H32K16.3 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201135 E01G6.11 No description available WB:WBGene00201136 C24A8.12 No description available WB:WBGene00201137 C02G6.5 Is affected by cep-1 and hmg-3 based on RNA-seq studies. WB:WBGene00201138 T21B10.13 No description available WB:WBGene00201139 F20B10.11 No description available WB:WBGene00201140 C50E10.14 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201141 Y76B12C.10 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 and hlh-26 based on RNA-seq studies. WB:WBGene00201142 C11D2.100 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201143 F43C9.8 Is affected by set-2 based on RNA-seq studies. WB:WBGene00201145 F47F6.12 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201146 K08A8.24 Enriched in neurons based on RNA-seq studies. WB:WBGene00201147 Y53H1C.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00201148 R04F11.26 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00201149 B0457.15 Is affected by eat-2 based on microarray studies. WB:WBGene00201150 ZK757.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201151 Y57G11C.1140 Is affected by cep-1; pmt-2; and etr-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00201152 C10A4.11 No description available WB:WBGene00201153 C44B7.20 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-29 based on RNA-seq and microarray studies. WB:WBGene00201154 B0212.8 No description available WB:WBGene00201155 VF23B12L.1 No description available WB:WBGene00201156 C25F6.24 No description available WB:WBGene00201157 Y49E10.33 No description available WB:WBGene00201158 F38B6.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00201159 W05E10.18 No description available WB:WBGene00201160 T05A8.10 Is affected by Tunicamycin based on microarray studies. WB:WBGene00201161 K03H6.11 No description available WB:WBGene00201162 F43G9.19 Is affected by daf-2 based on microarray studies. WB:WBGene00201163 ZC53.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201164 T28B8.9 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00201165 Y110A7A.23 Is affected by cep-1; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00201166 B0350.79 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; alg-1; and glh-1 based on RNA-seq studies. WB:WBGene00201167 C02D4.15 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00201168 B0457.16 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including cep-1; dlc-1; and hda-2 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201169 F31B12.8 Is affected by ifo-1 based on microarray studies. WB:WBGene00201170 Y53C10A.22 Is affected by hpl-2 based on RNA-seq studies. WB:WBGene00201171 C46F11.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00201172 C27C7.11 No description available WB:WBGene00201173 C33G3.12 No description available WB:WBGene00201174 F22F1.9 No description available WB:WBGene00201175 C18A11.13 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00201176 B0310.11 No description available WB:WBGene00201177 ZC53.19 No description available WB:WBGene00201178 F38B6.20 No description available WB:WBGene00201179 F19B6.8 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00201180 B0563.16 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00201181 C16C2.9 No description available WB:WBGene00201182 T14B4.16 No description available WB:WBGene00201183 F12F6.18 Is affected by dlc-1; daf-2; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00201184 C43D7.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00201185 F58E6.17 No description available WB:WBGene00201186 R03D7.14 No description available WB:WBGene00201187 C54G4.15 No description available WB:WBGene00201188 DY3.11 No description available WB:WBGene00201189 Y57A10B.10 No description available WB:WBGene00201190 W03D8.12 Is affected by eat-2 based on microarray studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00201191 F57G4.14 Is affected by daf-2 based on microarray studies. WB:WBGene00201192 F16A11.9 Enriched in AFD; ASER; and PLM based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00201193 F25F1.4 Is affected by etr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201194 C09D8.13 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201195 Y113G7A.20 Enriched in neurons based on RNA-seq studies. WB:WBGene00201196 F46E10.15 Is affected by several genes including cep-1; hpl-2; and dlc-1 based on RNA-seq studies. WB:WBGene00201197 F17A2.15 No description available WB:WBGene00201198 C36E6.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201199 Y55F3BR.16 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201200 C10C5.11 Is affected by alg-1 based on RNA-seq studies. WB:WBGene00201201 C01G12.14 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201202 T24D1.6 Is affected by adr-1 and daf-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201203 C06G1.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00201204 F15A2.13 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201205 K05B2.9 No description available WB:WBGene00201206 K09E9.12 Enriched in AFD; ASER; PLM; and sensory neurons based on RNA-seq studies. Is affected by daf-16 based on RNA-seq studies. WB:WBGene00201207 Y71H9A.9 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00201208 F08F3.16 No description available WB:WBGene00201209 F32B4.10 No description available WB:WBGene00201210 F26F12.20 No description available WB:WBGene00201211 T23E1.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by dlc-1 and hlh-26 based on RNA-seq studies. WB:WBGene00201212 K02A4.11 Is affected by cep-1 and etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201213 F41E7.17 No description available WB:WBGene00201214 F55C10.11 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00201215 C11E4.13 No description available WB:WBGene00201216 F54D12.20 Is affected by nhr-86 based on RNA-seq studies. WB:WBGene00201217 R02F11.8 No description available WB:WBGene00201218 C16B8.11 Is affected by eat-2 based on microarray studies. WB:WBGene00201219 W08D2.13 Is affected by klf-1 and etr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201220 F15A8.15 Is affected by hmg-3 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00201221 T25D10.8 No description available WB:WBGene00201222 C27C7.12 No description available WB:WBGene00201223 F10E9.19 No description available WB:WBGene00201224 F46G11.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201225 T02E1.11 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00201226 F26G1.13 No description available WB:WBGene00201227 C11H1.11 No description available WB:WBGene00201228 M79.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201229 C18D1.19 No description available WB:WBGene00201230 F59D6.10 No description available WB:WBGene00201231 F14D12.13 No description available WB:WBGene00201232 H24G06.4 No description available WB:WBGene00201233 T01G5.10 No description available WB:WBGene00201234 D1014.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00201235 K06G5.9 No description available WB:WBGene00201236 F59C12.10 No description available WB:WBGene00201237 C38D4.11 No description available WB:WBGene00201238 ZK180.18 Is affected by set-2 and hda-2 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201239 F57G12.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201240 Y51H7C.35 No description available WB:WBGene00201241 F11A1.14 No description available WB:WBGene00201242 F29G9.16 No description available WB:WBGene00201243 F46F3.19 No description available WB:WBGene00201244 T25D10.9 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00201245 F56D1.13 No description available WB:WBGene00201246 T18H9.10 Is affected by cep-1; adr-1; and dlc-1 based on RNA-seq studies. WB:WBGene00201247 F31E8.19 Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201248 T23F2.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00201249 F35C11.12 No description available WB:WBGene00201250 C09H10.17 No description available WB:WBGene00201251 T07D1.11 No description available WB:WBGene00201252 F37C12.22 Is affected by daf-2 based on microarray studies. WB:WBGene00201253 K08A8.25 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00201254 C16E9.25 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201255 W10C8.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201256 K03H9.14 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00201257 F58H1.25 No description available WB:WBGene00201258 Y66D12A.29 Is affected by sodium arsenite based on RNA-seq studies. WB:WBGene00201259 F01E11.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00201260 Y76F7A.5 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00201261 R144.16 Is affected by daf-2; mett-10; and etr-1 based on microarray and RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00201262 T10H10.7 No description available WB:WBGene00201263 T05A6.18 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. WB:WBGene00201264 C12D8.24 Is affected by Tunicamycin and Cry5B based on microarray studies. WB:WBGene00201265 C41G11.17 No description available WB:WBGene00201266 Y73B6BL.284 No description available WB:WBGene00201267 T05A6.19 Is affected by cep-1 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00201268 F09C8.5 No description available WB:WBGene00201269 R01H5.1 No description available WB:WBGene00201270 F15C11.6 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00201271 Y75B8A.58 No description available WB:WBGene00201272 T13H10.17 No description available WB:WBGene00201273 F46B6.15 Is affected by hpl-2 and etr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201274 Y95B8A.16 Is affected by cep-1 and blmp-1 based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00201275 C52G5.10 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; dlc-1; and camt-1 based on RNA-seq studies. WB:WBGene00201276 C47G2.18 No description available WB:WBGene00201277 C30C11.11 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00201278 R04D3.13 Is affected by daf-2 based on RNA-seq studies. WB:WBGene00201279 C44C10.14 Is affected by several genes including hda-2; etr-1; and ikb-1 based on RNA-seq studies. WB:WBGene00201280 F56D1.14 Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201281 F26A10.25 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00201282 F38E11.24 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201283 C47E8.15 Is affected by daf-2 based on microarray studies. WB:WBGene00201284 F55C12.14 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00201285 T20G5.16 Is affected by daf-2 based on microarray studies. WB:WBGene00201286 F32D8.17 Enriched in neurons based on RNA-seq studies. Is affected by daf-2; eat-2; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00201287 H06I04.13 Enriched in AFD based on RNA-seq studies. WB:WBGene00201288 T05H4.16 No description available WB:WBGene00201289 C11E4.14 Is affected by daf-2 based on microarray studies. WB:WBGene00201290 Y43F8A.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201291 K08B4.41 Is affected by several genes including pgl-1; cep-1; and lag-1 based on RNA-seq studies. WB:WBGene00201292 C35A11.11 No description available WB:WBGene00201293 F57B1.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201294 F55C12.15 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201295 F46F6.5 Is affected by daf-2 based on microarray studies. WB:WBGene00201296 F47E1.15 No description available WB:WBGene00201297 F53B1.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00201298 ZK1193.10 Is affected by nhr-86 based on RNA-seq studies. WB:WBGene00201299 F10C1.18 No description available WB:WBGene00201300 Y54E10A.27 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00201301 C10F3.15 Is affected by several genes including cep-1; alg-1; and hda-2 based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00201302 F19D8.6 No description available WB:WBGene00201303 F33A8.11 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00201304 K08A8.26 Enriched in neurons based on RNA-seq studies. WB:WBGene00201305 F56F3.13 Is affected by mafr-1 based on microarray studies. WB:WBGene00201306 F57F10.6 No description available WB:WBGene00201307 C48C5.9 No description available WB:WBGene00201308 F47F2.7 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201309 K10D6.22 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00201310 C39H7.70 No description available WB:WBGene00201311 F34H10.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201312 T01B4.8 No description available WB:WBGene00201313 F09F9.16 No description available WB:WBGene00201314 F31F6.15 Is affected by prg-1 and spt-16 based on RNA-seq studies. WB:WBGene00201315 C16B8.12 No description available WB:WBGene00201316 C47C12.9 No description available WB:WBGene00201317 F11A6.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00201318 F52F12.17 Is affected by Tunicamycin based on microarray studies. WB:WBGene00201319 ZK858.9 No description available WB:WBGene00201320 R07E4.10 No description available WB:WBGene00201321 F53B1.15 No description available WB:WBGene00201322 ZK353.12 No description available WB:WBGene00201323 C10G6.52 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201324 H09G03.3 No description available WB:WBGene00201325 T01C2.5 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00201326 ZC53.20 No description available WB:WBGene00201327 T14B4.17 No description available WB:WBGene00201328 Y105C5B.1416 Is affected by ins-11; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00201329 F02C12.9 No description available WB:WBGene00201330 T14E8.6 Enriched in AVK based on RNA-seq studies. WB:WBGene00201331 K07A3.4 No description available WB:WBGene00201332 F16B3.4 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00201333 H40L08.5 No description available WB:WBGene00201334 T10A3.5 No description available WB:WBGene00201335 Y73B6BL.285 Is affected by cep-1 and hmg-3 based on RNA-seq studies. WB:WBGene00201336 F53B6.10 Is affected by daf-2 based on microarray studies. WB:WBGene00201337 T10C6.20 No description available WB:WBGene00201338 C54D2.16 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00201339 R03H10.10 No description available WB:WBGene00201340 C52B9.17 No description available WB:WBGene00201341 C49C3.22 No description available WB:WBGene00201342 R07H5.14 Is affected by ifo-1 and spr-5 based on microarray and RNA-seq studies. WB:WBGene00201343 C15H9.13 No description available WB:WBGene00201344 Y51A2D.36 No description available WB:WBGene00201345 F09F3.18 No description available WB:WBGene00201346 R11B5.11 No description available WB:WBGene00201347 ZK938.9 No description available WB:WBGene00201348 F28B12.5 No description available WB:WBGene00201349 R10E12.10 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 and eat-2 based on RNA-seq and microarray studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00201350 C28G1.8 No description available WB:WBGene00201351 Y51F10.13 No description available WB:WBGene00201352 C02B4.14 No description available WB:WBGene00201353 T20B5.5 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201354 Y51A2D.37 Enriched in AFD based on RNA-seq studies. WB:WBGene00201355 Y7A5A.19 No description available WB:WBGene00201356 ZK617.21 No description available WB:WBGene00201357 F58A4.22 No description available WB:WBGene00201358 F46F3.20 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201359 F52B10.20 No description available WB:WBGene00201360 C04C11.20 No description available WB:WBGene00201361 F54E4.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00201362 C36C9.8 No description available WB:WBGene00201363 Y73F8A.1171 No description available WB:WBGene00201364 F11D5.28 No description available WB:WBGene00201365 ZK930.12 No description available WB:WBGene00201366 T01C8.10 Is affected by several genes including cep-1; adr-1; and pmt-2 based on RNA-seq and microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00201367 R03C1.6 No description available WB:WBGene00201368 ZK643.12 No description available WB:WBGene00201369 F55F3.8 No description available WB:WBGene00201370 C07A12.14 Is affected by daf-2 and rnp-6 based on microarray and RNA-seq studies. WB:WBGene00201371 T19H12.14 Is affected by fluvastatin based on RNA-seq studies. WB:WBGene00201372 W06H8.15 Is affected by several genes including cep-1; hpl-2; and let-418 based on RNA-seq studies. WB:WBGene00201373 Y38E10A.31 Is affected by elli-1 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00201374 C10C6.12 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00201375 C05A9.7 No description available WB:WBGene00201376 Y67D8C.18 No description available WB:WBGene00201377 T19D2.10 No description available WB:WBGene00201378 F13D11.18 No description available WB:WBGene00201379 F14H12.15 No description available WB:WBGene00201380 F10C1.19 Is affected by daf-2 based on microarray studies. WB:WBGene00201381 C08G5.9 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00201382 C07A12.15 No description available WB:WBGene00201383 F25D7.10 Is affected by cep-1 and mrps-5 based on RNA-seq studies. WB:WBGene00201384 B0222.14 Is affected by hlh-26 based on RNA-seq studies. WB:WBGene00201385 F10E9.20 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201386 Y4C6B.100 No description available WB:WBGene00201387 H19M22.10 Is affected by pmt-2 based on microarray studies. WB:WBGene00201388 ZC64.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201389 ZK637.20 Is affected by hpl-2 and set-2 based on RNA-seq studies. WB:WBGene00201390 T28D9.15 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201391 C54E4.8 Is affected by eat-2 based on microarray studies. WB:WBGene00201392 K03A11.8 No description available WB:WBGene00201393 C36F7.23 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201394 F55A8.6 No description available WB:WBGene00201395 Y62F5A.15 No description available WB:WBGene00201396 R08C7.18 No description available WB:WBGene00201397 F46B6.16 No description available WB:WBGene00201398 F31C3.16 Is affected by several genes including atfs-1; nuo-6; and adr-1 based on RNA-seq studies. WB:WBGene00201399 F09C12.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00201400 R09E10.15 Is affected by lem-2 based on RNA-seq studies. WB:WBGene00201401 T28B11.22 Is affected by pmt-2 based on microarray studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00201402 C06E4.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00201403 LLC1.120 No description available WB:WBGene00201404 T24D8.14 No description available WB:WBGene00201405 Y51H7D.1 Enriched in neurons based on RNA-seq studies. WB:WBGene00201406 AH10.9 No description available WB:WBGene00201407 T26C12.9 No description available WB:WBGene00201408 T09B9.8 Is affected by daf-12 based on RNA-seq studies. WB:WBGene00201409 C56A3.14 No description available WB:WBGene00201410 ZC190.15 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201411 F56E3.20 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00201412 Y67D8C.19 No description available WB:WBGene00201413 T01B6.10 Is affected by adr-1 and daf-2 based on RNA-seq and microarray studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00201414 C52A10.4 Is affected by Ethanol and fluvastatin based on RNA-seq studies. WB:WBGene00201415 Y15E3A.12 No description available WB:WBGene00201416 C39D10.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00201417 F11D5.29 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00201418 C24H11.13 No description available WB:WBGene00201419 K08B12.13 Is affected by cep-1 and set-2 based on RNA-seq studies. WB:WBGene00201420 T27B1.7 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201421 C18B12.15 No description available WB:WBGene00201422 W04D2.13 No description available WB:WBGene00201423 ZK546.20 Is affected by nhr-86 and etr-1 based on RNA-seq studies. WB:WBGene00201424 VC5.14 No description available WB:WBGene00201425 F14F3.16 Is affected by ikb-1 based on RNA-seq studies. WB:WBGene00201426 C14F11.29 Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00201427 F55G1.20 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq and microarray studies. WB:WBGene00201428 F33H1.9 Is affected by daf-2 based on microarray studies. WB:WBGene00201429 F45H7.14 Is affected by ifo-1 based on microarray studies. WB:WBGene00201430 Y50D4C.10 No description available WB:WBGene00201431 F02E8.10 No description available WB:WBGene00201432 F42D1.13 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00201433 R153.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00201434 C47A10.14 No description available WB:WBGene00201435 C10G11.15 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00201436 ZC123.10 No description available WB:WBGene00201437 F31B12.9 No description available WB:WBGene00201438 F44E5.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00201439 C33F10.23 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201440 K02F2.9 No description available WB:WBGene00201441 F22B3.19 Is affected by bcat-1 based on RNA-seq studies. WB:WBGene00201442 T22B7.20 No description available WB:WBGene00201443 ZK617.22 Is affected by pmt-2 based on microarray studies. WB:WBGene00201444 B0213.25 No description available WB:WBGene00201445 F02E8.11 Is affected by daf-2 based on microarray studies. WB:WBGene00201446 F56F10.10 Is affected by daf-2 and eat-2 based on microarray studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00201447 T05C7.3 Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00201448 R06C1.13 Is affected by several genes including pgl-1; alg-1; and glh-1 based on RNA-seq studies. WB:WBGene00201449 F56A6.7 No description available WB:WBGene00201450 F46C3.9 Is affected by adr-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00201451 ZK863.11 No description available WB:WBGene00201452 F21H12.9 Is affected by daf-2 based on microarray studies. WB:WBGene00201453 W02G9.7 Enriched in AFD based on RNA-seq studies. Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00201454 C31G12.15 No description available WB:WBGene00201455 ZK39.13 No description available WB:WBGene00201456 Y65B4BR.10 Is affected by nhr-86 and etr-1 based on RNA-seq studies. WB:WBGene00201457 W01A11.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201458 VF15C11L.2 Enriched in AVK based on RNA-seq studies. Is affected by mrps-5 and etr-1 based on RNA-seq studies. WB:WBGene00201459 F12A10.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00201460 Y43H11AL.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00201461 W06F12.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00201462 H32C10.100 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00201463 Y69H2.24 No description available WB:WBGene00201464 T24A11.10 No description available WB:WBGene00201465 C26F1.14 No description available WB:WBGene00201466 C32A3.6 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and prg-1 based on RNA-seq studies. WB:WBGene00201467 F36H12.65 No description available WB:WBGene00201468 C09B8.17 No description available WB:WBGene00201469 Y59A8B.36 No description available WB:WBGene00201470 T01A4.5 No description available WB:WBGene00201471 Y97E10AL.5 No description available WB:WBGene00201472 F49E10.22 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00201473 R02D5.21 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; dpy-21; and alg-1 based on RNA-seq studies. WB:WBGene00201474 K07E12.7 No description available WB:WBGene00201475 C52G5.11 No description available WB:WBGene00201476 B0524.9 No description available WB:WBGene00201477 F08G5.20 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00201478 D2005.9 No description available WB:WBGene00201479 ZC449.9 Is affected by daf-2 based on microarray studies. WB:WBGene00201480 C32A9.5 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00201481 C15B12.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00201482 T11F9.28 No description available WB:WBGene00201483 T12C9.9 No description available WB:WBGene00201484 F36D1.21 No description available WB:WBGene00201485 F40F4.9 Is affected by daf-2 based on microarray studies. WB:WBGene00201486 C14F11.30 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00201487 B0350.80 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201488 K09A11.10 Is affected by several genes including daf-2; pmt-2; and hmg-3 based on RNA-seq and microarray studies. Is affected by 4-bromodiphenyl ether based on microarray studies. WB:WBGene00201489 C16E9.26 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201490 F13B12.14 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00201491 F47F6.13 No description available WB:WBGene00201492 C25F6.25 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201493 C09B7.10 No description available WB:WBGene00201494 H27M09.7 Is affected by rsr-2 based on RNA-seq studies. WB:WBGene00201495 T27F7.11 Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00201496 F56H11.12 No description available WB:WBGene00201497 Y17G7B.24 Enriched in AFD based on RNA-seq studies. Is affected by ins-11 based on RNA-seq studies. WB:WBGene00201498 T22D1.21 No description available WB:WBGene00201499 K07A3.5 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00201500 C15C7.13 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00201501 F38A6.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00201502 F57B7.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201503 C25F6.26 Enriched in AFD based on RNA-seq studies. Is affected by cep-1 and alg-1 based on RNA-seq studies. WB:WBGene00201504 K01A12.9 No description available WB:WBGene00201505 C34F11.17 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201506 C25F6.27 No description available WB:WBGene00201507 K03H4.7 Is affected by cep-1; dlc-1; and daf-2 based on RNA-seq and microarray studies. WB:WBGene00201508 F37D6.11 No description available WB:WBGene00201509 F09D5.9 No description available WB:WBGene00201510 C05E7.6 No description available WB:WBGene00201511 Y46E12A.9 No description available WB:WBGene00201512 K06C4.24 Is affected by daf-2 based on microarray studies. WB:WBGene00201513 ZK1290.22 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00201514 R107.11 No description available WB:WBGene00201515 K01A6.20 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201516 F45B8.20 No description available WB:WBGene00201517 ZC247.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00201518 C26G2.10 No description available WB:WBGene00201519 C18H2.7 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00201520 Y17G9A.89 No description available WB:WBGene00201521 K02A4.12 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201522 F16F9.17 No description available WB:WBGene00201523 M01A8.3 Is affected by set-2 based on RNA-seq studies. WB:WBGene00201524 T01C1.11 No description available WB:WBGene00201525 K08A8.27 No description available WB:WBGene00201526 T14F9.19 No description available WB:WBGene00201527 C07E3.16 No description available WB:WBGene00201528 F35D2.15 No description available WB:WBGene00201529 M70.12 Is affected by daf-2 based on microarray studies. WB:WBGene00201530 F29F11.17 No description available WB:WBGene00201531 T06F4.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00201532 C06E4.20 Enriched in neurons based on RNA-seq studies. WB:WBGene00201533 T01H10.9 Is affected by daf-2 based on microarray studies. WB:WBGene00201534 Y48G8AR.7 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201535 ZK381.57 No description available WB:WBGene00201536 F13A2.13 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00201537 K01D12.18 Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00201538 C55A6.19 Is affected by adr-1; etr-1; and hlh-26 based on RNA-seq studies. WB:WBGene00201539 M01A8.4 No description available WB:WBGene00201540 C54D2.17 No description available WB:WBGene00201541 H14A12.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201542 Y51B9A.13 Is affected by lem-2; emr-1; and lag-1 based on RNA-seq studies. WB:WBGene00201543 F43B10.4 No description available WB:WBGene00201544 F12D9.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00201545 K02A2.9 No description available WB:WBGene00201546 C35B1.10 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00201547 F54H12.9 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00201548 Y37D8A.28 No description available WB:WBGene00201549 F35D2.16 Is affected by several genes including daf-2; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201550 C05B10.19 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00201551 C02C6.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00201552 F28D1.21 No description available WB:WBGene00201553 F45B8.21 No description available WB:WBGene00201554 Y46E12A.10 No description available WB:WBGene00201555 C29E6.16 No description available WB:WBGene00201556 D1022.16 Is affected by daf-2 based on microarray studies. WB:WBGene00201557 C03A3.7 Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201558 F02A9.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201559 F11D5.30 No description available WB:WBGene00201560 F23H12.19 No description available WB:WBGene00201561 C15H7.9 No description available WB:WBGene00201562 T19D7.10 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00201563 F46F3.21 Is affected by several genes including eat-2; cep-1; and let-418 based on RNA-seq and microarray studies. WB:WBGene00201564 F13D11.19 Is affected by cep-1 and spr-5 based on RNA-seq studies. WB:WBGene00201565 C27H6.11 No description available WB:WBGene00201566 C04D8.4 Enriched in AVK and neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201567 ZK40.8 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00201568 Y73B6BL.286 Is affected by daf-2 and mrps-5 based on microarray and RNA-seq studies. WB:WBGene00201569 F32B5.15 No description available WB:WBGene00201570 F09E5.22 No description available WB:WBGene00201571 C34F11.18 No description available WB:WBGene00201572 R04D3.14 Is affected by daf-2; eat-2; and pmt-2 based on microarray studies. WB:WBGene00201573 T06A4.6 No description available WB:WBGene00201574 Y67D8C.20 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201575 F46E10.16 No description available WB:WBGene00201576 C49H3.15 No description available WB:WBGene00201577 T14F9.20 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201578 M04B2.12 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. WB:WBGene00201579 C55H1.5 No description available WB:WBGene00201580 F08F1.20 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201581 F33G12.9 No description available WB:WBGene00201582 F47F2.8 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201583 C24B5.9 No description available WB:WBGene00201584 F16F9.18 No description available WB:WBGene00201585 T05G5.16 No description available WB:WBGene00201586 T04C12.30 Is affected by cep-1; adr-1; and etr-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00201587 ZK867.20 Is affected by daf-2 based on microarray studies. WB:WBGene00201588 Y71F9AR.8 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00201589 D1081.17 Is affected by several genes including cep-1; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00201590 F38B6.21 No description available WB:WBGene00201591 F18A11.12 No description available WB:WBGene00201592 B0350.81 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00201593 C42D8.19 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00201594 C07H6.18 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00201595 F22F1.10 No description available WB:WBGene00201596 C29H12.13 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00201597 Y102A11A.15 Is affected by dlc-1 and camt-1 based on RNA-seq studies. WB:WBGene00201598 H30A04.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00201599 ZK836.19 Is affected by ifo-1 based on microarray studies. WB:WBGene00201600 K02B2.38 Is affected by several genes including met-2; spr-5; and lem-2 based on RNA-seq studies. WB:WBGene00201601 Y97E10AM.3 No description available WB:WBGene00201602 F42C5.16 Enriched in AVK based on RNA-seq studies. Is affected by cep-1 and ints-5 based on RNA-seq studies. WB:WBGene00201603 ZK563.10 No description available WB:WBGene00201604 C05A9.8 No description available WB:WBGene00201605 F15G9.9 No description available WB:WBGene00201606 C30C11.12 No description available WB:WBGene00201607 C45G7.12 No description available WB:WBGene00201608 Y50D7A.18 No description available WB:WBGene00201609 F59F5.10 Is affected by daf-2 based on microarray studies. WB:WBGene00201610 T24D8.15 Is affected by pmt-2 based on microarray studies. WB:WBGene00201611 F25F8.6 No description available WB:WBGene00201612 F09G2.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00201613 E01G6.12 No description available WB:WBGene00201614 C34H3.21 No description available WB:WBGene00201615 R52.12 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00201616 Y17D7B.13 No description available WB:WBGene00201617 F52C9.10 No description available WB:WBGene00201618 R09A8.8 No description available WB:WBGene00201619 C50B6.15 No description available WB:WBGene00201620 C53B7.12 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and hlh-26 based on RNA-seq studies. WB:WBGene00201621 F58F12.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201622 T13A10.63 No description available WB:WBGene00201623 ZK131.14 Is affected by elli-1 and adr-1 based on microarray and RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00201624 C47G2.19 Is affected by daf-2 based on microarray studies. WB:WBGene00201625 F45D3.15 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and mrps-5 based on microarray and RNA-seq studies. Is affected by Tunicamycin and Cadmium Chloride based on microarray and RNA-seq studies. WB:WBGene00201626 F17C11.21 Is affected by adr-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00201627 Y71F9AR.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00201628 C33G3.13 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00201629 C41H7.11 No description available WB:WBGene00201630 C28F5.7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00201631 F22B7.16 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201632 F48C5.8 No description available WB:WBGene00201633 F13D11.20 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00201634 C18F3.11 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201636 F10E9.21 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201637 C54E4.9 No description available WB:WBGene00201638 F53H4.7 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00201639 Y54F10AM.14 No description available WB:WBGene00201640 C09G12.19 Enriched in neurons based on RNA-seq studies. Is affected by hpl-2; nfki-1; and etr-1 based on RNA-seq studies. WB:WBGene00201641 F46F6.6 No description available WB:WBGene00201642 C08B11.13 Enriched in AVK based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201643 K06C4.25 Enriched in neurons based on RNA-seq studies. WB:WBGene00201644 F31E8.20 Enriched in neurons based on RNA-seq studies. WB:WBGene00201645 F16F9.19 No description available WB:WBGene00201646 ZC412.13 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; hpl-2; and fzo-1 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; iron oxide nanoparticle; and silicon dioxide nanoparticle based on RNA-seq and microarray studies. WB:WBGene00201647 F54D12.21 No description available WB:WBGene00201648 C18F3.12 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00201649 H30A04.12 No description available WB:WBGene00201650 Y54G2A.69 No description available WB:WBGene00201651 W07E11.7 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00201652 T14B4.18 Enriched in neurons based on RNA-seq studies. WB:WBGene00201653 F25H8.23 No description available WB:WBGene00201654 K11C4.12 Is affected by cep-1; dpy-21; and etr-1 based on RNA-seq studies. WB:WBGene00201655 C39D10.17 Is affected by daf-2 based on microarray studies. WB:WBGene00201656 CE7X_3.3 Is affected by mafr-1 and lag-1 based on microarray and RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201657 C55A6.20 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201658 F42H10.16 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201659 Y116A8B.97 No description available WB:WBGene00201660 R03E9.10 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00201661 W02G9.8 No description available WB:WBGene00201662 ZC308.6 Is affected by chd-3; let-418; and dlc-1 based on RNA-seq studies. WB:WBGene00201663 Y39A3A.9 No description available WB:WBGene00201664 C27H6.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00201665 W09G3.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00201666 VK10D6R.2 No description available WB:WBGene00201667 T06A4.7 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00201668 T07H3.9 No description available WB:WBGene00201669 cTel29B.2 No description available WB:WBGene00201670 Y48B6A.23 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201671 Y55F3BR.17 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00201672 C49F8.13 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201673 F49E10.23 Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00201674 C06A8.16 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00201675 R153.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00201676 M05B5.10 No description available WB:WBGene00201677 F55C5.16 Is affected by pmt-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201678 R13H8.5 Is affected by cep-1; dlc-1; and lpd-3 based on RNA-seq studies. WB:WBGene00201679 R02D5.22 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201680 K06A1.10 Is affected by cep-1 and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00201681 Y53F4A.5 No description available WB:WBGene00201682 ZK973.24 Is affected by daf-2 based on microarray studies. WB:WBGene00201683 F09G8.13 No description available WB:WBGene00201684 Y69A2AR.44 Is affected by adr-1 based on RNA-seq studies. Is affected by Ethanol based on RNA-seq studies. WB:WBGene00201685 C53C9.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201686 F54C4.7 No description available WB:WBGene00201687 C03A3.8 No description available WB:WBGene00201688 Y71A12B.31 No description available WB:WBGene00201689 C04D8.5 No description available WB:WBGene00201690 F25H8.24 No description available WB:WBGene00201691 Y43F8B.27 Enriched in neurons based on RNA-seq studies. WB:WBGene00201692 R01E6.18 No description available WB:WBGene00201693 Y38F2AL.11 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00201694 C24A11.13 No description available WB:WBGene00201695 CD4.16 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201696 Y39G8B.12 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201697 B0212.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00201698 ZK867.21 No description available WB:WBGene00201699 ZC477.19 Is affected by daf-2 based on microarray studies. WB:WBGene00201700 F38B6.22 No description available WB:WBGene00201701 Y49F6A.8 Is affected by eat-2 based on microarray studies. WB:WBGene00201702 C15H7.10 Is affected by daf-2 based on microarray studies. WB:WBGene00201703 R08B4.14 No description available WB:WBGene00201704 ZK945.15 No description available WB:WBGene00201705 F08C6.16 No description available WB:WBGene00201706 F55D10.9 No description available WB:WBGene00201707 M01G4.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00201708 Y51H7C.36 No description available WB:WBGene00201709 Y43F8A.10 No description available WB:WBGene00201710 C01H6.11 No description available WB:WBGene00201711 M04B2.13 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00201712 B0403.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00201713 Y49E10.34 No description available WB:WBGene00201714 C02C6.11 No description available WB:WBGene00201715 W09C2.12 No description available WB:WBGene00201716 C05C12.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201717 C41G11.18 Enriched in NSM and neurons based on RNA-seq studies. Is affected by unc-70 based on RNA-seq studies. WB:WBGene00201718 F14H12.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00201719 K11H3.13 Is affected by daf-2 based on microarray studies. WB:WBGene00201720 F46C8.21 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201721 F52H2.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00201722 E02A10.10 No description available WB:WBGene00201723 C37A5.15 No description available WB:WBGene00201724 Y108G3AL.8 No description available WB:WBGene00201725 R90.12 Is affected by cep-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00201726 ZK381.58 No description available WB:WBGene00201727 T07F12.11 No description available WB:WBGene00201728 Y51H7C.37 No description available WB:WBGene00201729 C16E9.27 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; hpl-2; and set-2 based on RNA-seq and microarray studies. WB:WBGene00201730 F38A6.8 No description available WB:WBGene00201731 Y67D8A.9 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00201732 F28F5.16 Is affected by spr-5 based on RNA-seq studies. WB:WBGene00201733 R12H7.7 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201734 ZK154.8 Is affected by daf-2 based on microarray studies. WB:WBGene00201735 C04A2.12 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00201736 F11D5.31 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201737 F32B4.11 No description available WB:WBGene00201738 W07G1.21 No description available WB:WBGene00201739 F58B4.11 Enriched in AVK based on RNA-seq studies. WB:WBGene00201740 C41G11.19 No description available WB:WBGene00201741 R08E3.11 No description available WB:WBGene00201742 ZC21.16 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00201743 K09H11.14 Is affected by hmg-3; hmg-4; and spt-16 based on RNA-seq studies. WB:WBGene00201744 B0495.22 No description available WB:WBGene00201745 C14F5.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00201746 F15A8.16 Is affected by tdp-1 and hmg-3 based on RNA-seq studies. WB:WBGene00201747 ZC477.20 Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201748 F40H3.16 Enriched in sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201749 T12E12.44 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201750 W01A11.17 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00201751 W08F4.19 No description available WB:WBGene00201752 F44E5.14 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including met-2; dlc-1; and pmt-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201753 H36N01.5 Is affected by pmt-2 based on microarray studies. WB:WBGene00201754 ZK484.10 Is affected by pmt-2 and ifo-1 based on microarray studies. WB:WBGene00201755 C37A2.9 Is affected by cep-1 and set-2 based on RNA-seq studies. WB:WBGene00201756 C34H3.22 No description available WB:WBGene00201757 C25H3.20 Enriched in neurons based on RNA-seq studies. WB:WBGene00201758 Y59A8B.37 No description available WB:WBGene00201759 M176.14 No description available WB:WBGene00201760 F56A11.13 No description available WB:WBGene00201761 F42A9.14 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00201762 ZK377.12 No description available WB:WBGene00201763 W03G1.10 No description available WB:WBGene00201764 ZC412.14 No description available WB:WBGene00201765 C10H11.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201766 K08B4.42 Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00201767 Y39A3CL.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00201768 K02A11.11 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00201769 F09C12.14 No description available WB:WBGene00201770 C12D8.25 No description available WB:WBGene00201771 F48D6.6 No description available WB:WBGene00201772 Y73B3A.28 Is affected by Ethanol based on RNA-seq studies. WB:WBGene00201773 F42G2.10 No description available WB:WBGene00201774 K10C8.5 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 based on microarray studies. WB:WBGene00201775 F08G5.21 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00201776 C54E10.9 No description available WB:WBGene00201777 Y48G8AL.19 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00201778 H01A20.5 No description available WB:WBGene00201779 Y34B4A.18 No description available WB:WBGene00201780 Y73B3A.29 No description available WB:WBGene00201781 Y37H2A.17 No description available WB:WBGene00201782 Y26D4A.25 Is affected by spr-5 based on RNA-seq studies. WB:WBGene00201783 R10D12.19 Is affected by pmt-2 and set-2 based on microarray and RNA-seq studies. WB:WBGene00201784 C09B7.11 No description available WB:WBGene00201785 Y116F11B.23 Enriched in neurons based on RNA-seq studies. WB:WBGene00201786 F20D1.20 No description available WB:WBGene00201787 K07C5.17 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201788 T28D6.15 Is affected by cep-1; spt-16; and blmp-1 based on RNA-seq studies. WB:WBGene00201789 F11C1.16 Enriched in AVK based on RNA-seq studies. Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00201790 T24D11.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00201791 R07D5.9 No description available WB:WBGene00201792 T06H11.20 Is affected by daf-2 based on microarray studies. WB:WBGene00201793 E01H11.5 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00201794 Y105E8A.48 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00201795 C25E10.15 No description available WB:WBGene00201796 F02G3.7 No description available WB:WBGene00201797 T02E9.26 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00201798 F25G6.20 Is affected by daf-2 based on microarray studies. WB:WBGene00201799 T01C1.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00201800 C24A8.13 No description available WB:WBGene00201801 F55D12.8 No description available WB:WBGene00201802 Y80D3A.15 No description available WB:WBGene00201803 C55A6.21 No description available WB:WBGene00201804 C05A2.3 No description available WB:WBGene00201805 F52E1.15 Is affected by daf-2 based on microarray studies. WB:WBGene00201806 W01A11.18 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00201807 F28A12.7 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00201808 C34F6.16 No description available WB:WBGene00201809 W05E10.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00201810 C43D7.18 No description available WB:WBGene00201811 Y15E3A.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00201812 T14F9.21 No description available WB:WBGene00201813 B0310.12 Is affected by adr-2 based on RNA-seq studies. WB:WBGene00201814 F30H5.8 Is affected by pmt-2 and nfki-1 based on microarray and RNA-seq studies. WB:WBGene00201815 B0457.17 No description available WB:WBGene00201816 M04D5.6 No description available WB:WBGene00201817 ZK669.9 Is affected by met-2; spr-5; and camt-1 based on RNA-seq studies. WB:WBGene00201818 R186.14 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201819 C30D11.5 No description available WB:WBGene00201820 F54H5.11 Is affected by set-2 and cox-5B based on RNA-seq studies. WB:WBGene00201821 W06F12.8 No description available WB:WBGene00201822 M03E7.9 Is affected by pmt-2 and alh-4 based on microarray and RNA-seq studies. WB:WBGene00201823 C01C4.7 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201824 F46A9.11 No description available WB:WBGene00201825 F57G12.14 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201826 F13H10.11 No description available WB:WBGene00201827 F26D11.19 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00201828 Y15E3A.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201829 Y8G1A.3 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201830 Y54G2A.70 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00201831 Y60A9A.6 No description available WB:WBGene00201832 ZC449.10 No description available WB:WBGene00201833 F54E4.16 Enriched in neurons based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00201834 T09F5.19 No description available WB:WBGene00201835 F49E10.24 No description available WB:WBGene00201836 F13D11.21 No description available WB:WBGene00201837 F47B7.16 No description available WB:WBGene00201838 C26E6.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00201839 F22B5.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00201840 F57C7.14 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00201841 F57A10.9 No description available WB:WBGene00201842 Y40C5A.23 No description available WB:WBGene00201843 C34D1.14 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00201844 R31.5 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201845 ZK813.10 No description available WB:WBGene00201846 Y46E12A.11 Enriched in neurons based on RNA-seq studies. Is affected by adr-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00201847 T28C12.13 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201848 R11E3.16 No description available WB:WBGene00201849 ZK617.23 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201850 F32A6.13 Is affected by pmt-2 and alh-4 based on microarray and RNA-seq studies. WB:WBGene00201851 B0496.19 No description available WB:WBGene00201852 ZK662.9 Is affected by daf-2 and nfki-1 based on microarray and RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00201853 ZK867.22 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201854 F57F4.8 Is affected by daf-2 and fzo-1 based on microarray and RNA-seq studies. WB:WBGene00201855 C01B7.16 No description available WB:WBGene00201856 Y76A2B.9 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201857 T28C12.14 No description available WB:WBGene00201858 W04D2.14 Is affected by cep-1 and hmg-3 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201859 F52H2.14 No description available WB:WBGene00201860 F18E2.14 No description available WB:WBGene00201861 B0395.10 No description available WB:WBGene00201862 K03F8.4 No description available WB:WBGene00201863 T28B4.14 No description available WB:WBGene00201864 F54H5.12 Is affected by cep-1 and ifo-1 based on RNA-seq and microarray studies. WB:WBGene00201865 F31E8.21 Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00201866 F09D5.10 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00201867 C15A7.7 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00201868 W01A11.19 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201869 ZC247.8 No description available WB:WBGene00201870 F12D9.17 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00201871 T24B8.21 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00201872 C06E7.94 Is affected by lem-2 and emr-1 based on RNA-seq studies. WB:WBGene00201873 H14N18.8 No description available WB:WBGene00201874 T28B11.23 Is affected by daf-2 based on microarray studies. WB:WBGene00201875 F28H7.12 No description available WB:WBGene00201876 F39C12.8 No description available WB:WBGene00201877 R11G1.10 No description available WB:WBGene00201878 C39E9.19 No description available WB:WBGene00201879 W07G4.12 Is affected by pmt-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201880 T10B10.15 No description available WB:WBGene00201881 R01E6.19 No description available WB:WBGene00201882 T21C12.11 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00201883 R04F11.27 Enriched in neurons based on RNA-seq studies. WB:WBGene00201884 W06B11.11 No description available WB:WBGene00201885 Y46E12BR.2 No description available WB:WBGene00201886 Y40C7B.9 No description available WB:WBGene00201887 C53C7.8 No description available WB:WBGene00201888 Y39G8C.12 Is affected by set-2 based on RNA-seq studies. WB:WBGene00201889 C26E6.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00201890 Y39G10AL.6 No description available WB:WBGene00201891 W03G11.21 Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00201892 K02H8.6 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00201893 F15A2.14 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00201894 F41D9.14 No description available WB:WBGene00201895 R08E3.12 No description available WB:WBGene00201896 Y67D2.9 No description available WB:WBGene00201897 F01G10.20 No description available WB:WBGene00201898 VC5.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00201899 C30B5.16 Is affected by cep-1 and camt-1 based on RNA-seq studies. WB:WBGene00201900 T21C9.17 No description available WB:WBGene00201901 T09B4.19 Is affected by several genes including cep-1; etr-1; and hlh-26 based on RNA-seq studies. WB:WBGene00201902 F29F11.18 No description available WB:WBGene00201903 F22A3.17 No description available WB:WBGene00201904 C29A12.21 Enriched in neurons based on RNA-seq studies. WB:WBGene00201905 C25B8.12 No description available WB:WBGene00201906 W01H2.10 No description available WB:WBGene00201907 F58H1.26 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00201908 F09C8.6 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00201909 C04C11.21 Enriched in neurons based on RNA-seq studies. WB:WBGene00201910 B0280.20 No description available WB:WBGene00201911 F43E12.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00201912 T06F4.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00201913 2RSSE.8 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00201914 Y69E1A.14 No description available WB:WBGene00201915 F35G2.20 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00201916 C48B6.13 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00201917 Y57E12B.9 No description available WB:WBGene00201918 T06D8.16 No description available WB:WBGene00201919 T28B11.24 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201920 C33D12.15 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00201921 C05A9.9 No description available WB:WBGene00201922 ZC21.17 No description available WB:WBGene00201923 K10D6.23 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201924 F45H7.15 No description available WB:WBGene00201925 C04F1.5 Is affected by daf-2 based on microarray studies. WB:WBGene00201926 F52F12.18 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00201927 Y87G2A.24 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00201928 F59B10.9 No description available WB:WBGene00201929 F25H8.25 No description available WB:WBGene00201930 C18D1.20 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201931 W06G6.19 No description available WB:WBGene00201932 C16H3.7 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201933 F22E12.12 Is affected by pmt-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00201934 C52D10.130 No description available WB:WBGene00201935 mir-8210 No description available WB:WBGene00201936 K10D6.24 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. Is affected by Tunicamycin and silicon dioxide nanoparticle based on microarray studies. WB:WBGene00201937 C29H12.14 No description available WB:WBGene00201938 K09C6.11 Is affected by eat-2 based on microarray studies. WB:WBGene00201939 W05E10.20 No description available WB:WBGene00201940 F46F3.22 Enriched in neurons based on RNA-seq studies. WB:WBGene00201941 C37E2.9 Is affected by cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00201942 F12F6.19 No description available WB:WBGene00201943 F13D11.22 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00201944 F54D5.22 No description available WB:WBGene00201945 C09B9.84 No description available WB:WBGene00201946 F26A10.26 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201947 F41H8.5 No description available WB:WBGene00201948 ZC250.11 No description available WB:WBGene00201949 F45D3.16 No description available WB:WBGene00201950 F09E5.23 No description available WB:WBGene00201951 F25H10.10 No description available WB:WBGene00201952 F46F3.23 No description available WB:WBGene00201953 K06A5.10 Is affected by iron oxide nanoparticle based on microarray studies. WB:WBGene00201954 ZC506.9 No description available WB:WBGene00201955 ZK470.13 No description available WB:WBGene00201956 T04C9.12 No description available WB:WBGene00201957 K10C9.12 No description available WB:WBGene00201958 F56C3.12 No description available WB:WBGene00201959 C14F11.31 Is affected by pmt-2 based on microarray studies. WB:WBGene00201960 C05E11.17 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00201961 C08A9.12 No description available WB:WBGene00201962 T23F11.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00201963 Y37A1B.337 No description available WB:WBGene00201964 F25D1.11 Is affected by several genes including cep-1; tdp-1; and etr-1 based on RNA-seq studies. WB:WBGene00201965 F10D11.8 No description available WB:WBGene00201966 C37H5.16 Is affected by etr-1 and cox-5B based on RNA-seq studies. WB:WBGene00201967 F17E5.6 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00201968 VC5.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00201969 H03A11.12 Is affected by daf-2 based on microarray studies. WB:WBGene00201970 ZK899.12 No description available WB:WBGene00201971 T06D8.17 No description available WB:WBGene00201972 T26H2.16 No description available WB:WBGene00201973 Y105E8A.49 No description available WB:WBGene00201974 T07D10.12 No description available WB:WBGene00201975 K02E10.12 Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00201976 Y47H9C.20 Is affected by nfki-1 and camt-1 based on RNA-seq studies. WB:WBGene00201977 C01G12.15 No description available WB:WBGene00201978 R03A10.13 No description available WB:WBGene00201979 K04C2.11 No description available WB:WBGene00201980 K08A8.28 Is affected by cep-1; set-2; and ikb-1 based on RNA-seq studies. WB:WBGene00201981 F10F2.16 Enriched in neurons based on RNA-seq studies. Is affected by tdp-1 based on RNA-seq studies. WB:WBGene00201982 C04A2.13 No description available WB:WBGene00201983 F11H8.9 No description available WB:WBGene00201984 Y42H9B.10 Is affected by chd-3; let-418; and lpd-3 based on RNA-seq studies. WB:WBGene00201985 Y65A5A.27 No description available WB:WBGene00201986 ZK370.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00201987 F35B12.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00201988 C44B7.21 Is affected by pmt-2 based on microarray studies. WB:WBGene00201989 F43G9.20 No description available WB:WBGene00201990 Y92C3A.8 No description available WB:WBGene00201991 C07G1.14 Is affected by several genes including eat-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00201992 C13C12.6 Is affected by hpl-2; hmg-3; and set-2 based on RNA-seq studies. WB:WBGene00201993 C27C12.10 No description available WB:WBGene00201994 T25C12.10 Is affected by daf-2; eat-2; and mrps-5 based on microarray and RNA-seq studies. WB:WBGene00201995 K12G11.13 No description available WB:WBGene00201996 F47F2.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00201997 T27F2.7 Is affected by daf-2 based on microarray studies. WB:WBGene00201998 K11C4.13 Is affected by several genes including cep-1; set-2; and fzo-1 based on RNA-seq studies. WB:WBGene00201999 F54C8.11 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00202000 Y38F1A.13 Is affected by chd-3 and let-418 based on RNA-seq studies. WB:WBGene00202001 ZK721.6 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00202002 C34E11.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202003 W04E12.13 No description available WB:WBGene00202004 C47G2.20 No description available WB:WBGene00202005 W06A7.11 No description available WB:WBGene00202006 C13C4.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202007 Y67A6A.3 Is affected by spt-16 based on RNA-seq studies. WB:WBGene00202008 B0478.26 No description available WB:WBGene00202009 K08D9.8 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00202010 C09B8.18 Is affected by mett-10 and etr-1 based on RNA-seq studies. WB:WBGene00202011 R13H4.13 Enriched in neurons based on RNA-seq studies. Is affected by pmt-2 and etr-1 based on microarray and RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202012 F09B9.7 No description available WB:WBGene00202013 Y73F8A.1172 Is affected by pmt-2 based on microarray studies. WB:WBGene00202014 Y38F2AR.21 No description available WB:WBGene00202015 C50C3.18 No description available WB:WBGene00202016 C48A7.15 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202017 F36H1.16 No description available WB:WBGene00202018 B0454.24 No description available WB:WBGene00202019 Y104H12D.9 No description available WB:WBGene00202020 F52B10.21 No description available WB:WBGene00202021 C14F11.32 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202022 F40F9.16 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00202023 F44A2.11 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00202024 VK04G11.2 No description available WB:WBGene00202025 T28B8.10 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00202026 C04A2.14 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202027 F32A7.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202028 F46G11.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00202029 K03C7.14 Is affected by several genes including daf-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00202030 C24F3.7 Enriched in neurons based on RNA-seq studies. Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00202031 C11E4.15 No description available WB:WBGene00202032 T26H10.9 No description available WB:WBGene00202033 K01C8.11 No description available WB:WBGene00202034 T23F2.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202035 K02A4.13 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00202036 F46F6.7 No description available WB:WBGene00202037 W09C2.13 No description available WB:WBGene00202038 C34F6.17 No description available WB:WBGene00202039 F52F12.19 No description available WB:WBGene00202040 C27C7.13 No description available WB:WBGene00202041 Y69A2AR.45 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00202042 F19D8.7 No description available WB:WBGene00202043 ZK180.19 No description available WB:WBGene00202044 F46G11.20 No description available WB:WBGene00202045 ZK757.9 No description available WB:WBGene00202046 F43D9.13 Is affected by dpy-21 and mrps-5 based on RNA-seq studies. WB:WBGene00202047 F59D6.11 No description available WB:WBGene00202048 M117.13 No description available WB:WBGene00202049 F33C8.8 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00202050 M79.15 Is affected by met-2 based on RNA-seq studies. WB:WBGene00202051 C14H10.5 No description available WB:WBGene00202052 C41G11.20 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; daf-2; and unc-70 based on RNA-seq and microarray studies. WB:WBGene00202053 T04C12.31 No description available WB:WBGene00202054 F57B7.14 No description available WB:WBGene00202055 ZK993.4 No description available WB:WBGene00202056 R03A10.14 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202057 C10G11.16 No description available WB:WBGene00202058 F13H6.27 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00202059 C06G1.17 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00202060 F45B8.22 No description available WB:WBGene00202061 F56D1.15 Is affected by dlc-1 and klf-1 based on RNA-seq studies. WB:WBGene00202062 F15A8.17 No description available WB:WBGene00202063 W10C8.16 No description available WB:WBGene00202064 C44B12.12 No description available WB:WBGene00202065 K02B9.9 No description available WB:WBGene00202066 F56F3.14 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; alg-1; and dlc-1 based on RNA-seq studies. WB:WBGene00202067 T05B11.12 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00202068 F01E11.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00202069 T20G5.17 Enriched in muscle cell based on RNA-seq studies. Is affected by alg-1 and daf-12 based on RNA-seq studies. WB:WBGene00202070 R01H5.2 No description available WB:WBGene00202071 T09D3.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00202072 ZK381.59 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202073 Y105C5A.1280 Enriched in AFD based on RNA-seq studies. WB:WBGene00202074 T28B11.25 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00202075 D1073.3 No description available WB:WBGene00202076 K04A8.17 Is affected by cep-1 and dlc-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202077 F46B6.17 No description available WB:WBGene00202078 F38G1.5 No description available WB:WBGene00202079 F38E11.25 No description available WB:WBGene00202080 C10F3.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202081 F08C6.17 Enriched in AVK based on RNA-seq studies. WB:WBGene00202082 F55C12.16 Enriched in neurons based on RNA-seq studies. Is affected by ifo-1 based on microarray studies. WB:WBGene00202083 F54F3.6 Is affected by ifo-1 based on microarray studies. WB:WBGene00202084 C51E3.11 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by bcat-1 and camt-1 based on RNA-seq studies. WB:WBGene00202085 F15C11.7 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00202086 F45E10.3 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00202087 K04G2.15 No description available WB:WBGene00202088 C05D12.11 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle and Oligosaccharides based on microarray studies. WB:WBGene00202089 T01G1.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00202090 F59C12.11 No description available WB:WBGene00202091 K08A8.29 No description available WB:WBGene00202092 F53B1.16 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00202093 ZC123.11 Enriched in neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202094 Y75B8A.59 No description available WB:WBGene00202095 K02A4.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00202096 Y66A7AL.9 No description available WB:WBGene00202097 C05B10.20 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202098 C29F4.7 No description available WB:WBGene00202099 C02E7.17 No description available WB:WBGene00202100 K02A4.15 Enriched in sensory neurons based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202101 Y39A3CR.10 No description available WB:WBGene00202102 D1053.7 No description available WB:WBGene00202103 F22B3.20 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202104 ZK563.11 Enriched in neurons based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00202105 F55C12.17 No description available WB:WBGene00202106 C09B7.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00202107 F44B9.11 No description available WB:WBGene00202108 F23B12.10 Is affected by spt-16 based on RNA-seq studies. WB:WBGene00202109 F59B10.10 Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00202110 M01D7.10 No description available WB:WBGene00202111 C31G12.16 Is affected by daf-2 based on microarray studies. WB:WBGene00202112 T27B1.8 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00202113 B0457.18 Is affected by cep-1; dlc-1; and npr-8 based on RNA-seq studies. WB:WBGene00202114 R07G3.15 No description available WB:WBGene00202115 F34H10.8 No description available WB:WBGene00202116 C50E10.15 No description available WB:WBGene00202117 Y92C3A.9 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202118 K02A2.10 No description available WB:WBGene00202119 K06G5.10 Is affected by daf-2 based on microarray studies. WB:WBGene00202120 C43H6.11 No description available WB:WBGene00202121 C10G6.53 No description available WB:WBGene00202122 F29G9.17 No description available WB:WBGene00202123 K08E7.13 No description available WB:WBGene00202124 F22E12.13 Is affected by cep-1 and mrps-5 based on RNA-seq studies. WB:WBGene00202125 T09A5.21 No description available WB:WBGene00202126 Y51H7C.38 Enriched in neurons based on RNA-seq studies. WB:WBGene00202127 C47G2.21 No description available WB:WBGene00202128 F32H5.8 Is affected by cyc-1 based on microarray studies. WB:WBGene00202129 C09G5.12 No description available WB:WBGene00202130 C31H5.9 No description available WB:WBGene00202131 T06E4.19 No description available WB:WBGene00202132 C16B8.13 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00202133 C51E3.12 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; pmt-2; and fzo-1 based on RNA-seq and microarray studies. WB:WBGene00202134 C11E4.16 No description available WB:WBGene00202135 B0563.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00202136 F25D7.11 No description available WB:WBGene00202137 Y54E10A.28 No description available WB:WBGene00202138 C50E10.16 No description available WB:WBGene00202139 C24H12.15 No description available WB:WBGene00202140 F47C8.8 Is affected by Tunicamycin based on microarray studies. WB:WBGene00202141 R06B10.8 No description available WB:WBGene00202142 C36F7.24 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202143 Y38A10A.10 No description available WB:WBGene00202144 C24A1.7 No description available WB:WBGene00202145 W02B8.13 No description available WB:WBGene00202146 F48B9.12 No description available WB:WBGene00202147 F41C6.14 No description available WB:WBGene00202148 F32B5.16 Is affected by lem-2 based on RNA-seq studies. WB:WBGene00202149 F10E9.22 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202150 F33C8.9 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00202151 W05E10.21 No description available WB:WBGene00202152 C31H5.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00202153 F39B1.5 No description available WB:WBGene00202154 K07C6.17 No description available WB:WBGene00202155 C36F7.25 Is affected by daf-2 based on microarray studies. WB:WBGene00202156 C34G6.13 No description available WB:WBGene00202157 EGAP3.4 No description available WB:WBGene00202158 R10E12.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202159 K03H9.15 No description available WB:WBGene00202160 K08A8.30 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00202161 C04E6.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00202162 Y53H1C.11 No description available WB:WBGene00202163 F44A2.12 Is affected by cep-1 and fzo-1 based on RNA-seq studies. WB:WBGene00202164 F47F6.14 No description available WB:WBGene00202165 R05G9.4 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00202166 B0350.82 No description available WB:WBGene00202167 T21B6.17 No description available WB:WBGene00202168 F43C9.9 Is affected by cep-1; adr-1; and set-2 based on RNA-seq studies. WB:WBGene00202169 F28F5.17 Is affected by pmt-2 based on microarray studies. WB:WBGene00202170 C31H5.11 No description available WB:WBGene00202171 F20B10.12 Enriched in neurons based on RNA-seq studies. Is affected by Cry5B and Oligosaccharides based on microarray studies. WB:WBGene00202172 T06F4.20 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00202173 F53B6.11 No description available WB:WBGene00202174 C10A4.12 Is affected by daf-2 and pmt-2 based on microarray studies. WB:WBGene00202175 F11A6.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00202176 H08J11.13 No description available WB:WBGene00202177 VC5.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00202178 F38A6.9 Is affected by let-418 based on RNA-seq studies. WB:WBGene00202179 Y57G11C.1141 No description available WB:WBGene00202180 B0350.83 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202181 C17H11.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202182 F40F11.5 No description available WB:WBGene00202183 C34E11.19 No description available WB:WBGene00202184 C11D2.101 No description available WB:WBGene00202185 F41E7.18 Is affected by dpy-21 and etr-1 based on RNA-seq studies. WB:WBGene00202186 C10F3.17 No description available WB:WBGene00202187 M01E10.5 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and lag-1 based on microarray and RNA-seq studies. WB:WBGene00202188 F45F2.16 No description available WB:WBGene00202189 Y67D2.10 No description available WB:WBGene00202190 C33D12.16 No description available WB:WBGene00202191 C28G1.9 No description available WB:WBGene00202192 C23H4.13 No description available WB:WBGene00202193 Y51H7C.39 No description available WB:WBGene00202194 R13A5.16 Is affected by set-2 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00202195 T27D1.4 No description available WB:WBGene00202196 C09D8.14 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00202197 F43E12.8 No description available WB:WBGene00202198 C04C11.22 Enriched in neurons based on RNA-seq studies. WB:WBGene00202199 F38B6.23 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202200 F47F2.10 No description available WB:WBGene00202201 K03B8.23 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00202202 Y48C3A.24 No description available WB:WBGene00202203 C54E4.10 No description available WB:WBGene00202204 K06A4.14 Is affected by daf-2 based on microarray studies. WB:WBGene00202205 W04G3.15 Is affected by Tunicamycin based on microarray studies. WB:WBGene00202206 C03B1.16 No description available WB:WBGene00202207 F26F2.12 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00202208 Y113G7A.21 No description available WB:WBGene00202209 Y41D4B.31 No description available WB:WBGene00202210 Y39G8C.13 No description available WB:WBGene00202211 T22B7.21 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00202212 C09D8.15 Is affected by several genes including pgl-1; cep-1; and glh-1 based on RNA-seq studies. WB:WBGene00202213 K08A2.16 Is affected by eat-2 based on microarray studies. WB:WBGene00202214 R07B1.23 No description available WB:WBGene00202215 F35D2.17 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00202216 Y55F3BR.18 No description available WB:WBGene00202217 F38B6.24 Enriched in neurons based on RNA-seq studies. WB:WBGene00202218 M60.14 No description available WB:WBGene00202219 Y39A1B.9 No description available WB:WBGene00202220 F45G2.13 No description available WB:WBGene00202221 T01B10.14 No description available WB:WBGene00202222 F58F12.11 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00202223 K10G6.8 No description available WB:WBGene00202224 R05C11.5 Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00202225 C40C9.16 No description available WB:WBGene00202226 C05A9.10 Is affected by cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202227 C03H12.3 No description available WB:WBGene00202228 B0454.25 No description available WB:WBGene00202229 F57G4.15 No description available WB:WBGene00202230 K02F2.10 Enriched in neurons based on RNA-seq studies. Is affected by klf-1 based on RNA-seq studies. WB:WBGene00202231 B0457.19 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including cep-1; set-2; and dlc-1 based on RNA-seq studies. WB:WBGene00202232 C46C2.11 No description available WB:WBGene00202233 F55D12.9 Is affected by ifo-1 based on microarray studies. WB:WBGene00202234 F36H12.66 No description available WB:WBGene00202235 T25D10.10 No description available WB:WBGene00202236 W04G3.16 No description available WB:WBGene00202237 C16C2.10 Is affected by cep-1; chd-3; and let-418 based on RNA-seq studies. WB:WBGene00202238 C45G3.6 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00202239 Y37E11B.14 Is affected by daf-2; met-2; and spr-5 based on microarray and RNA-seq studies. WB:WBGene00202240 F09G2.13 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. WB:WBGene00202241 F54B11.14 Enriched in AFD; ASER; and PLM based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00202242 T23C6.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00202243 C14H10.6 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00202244 ZC64.16 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202245 K10D6.25 Enriched in neurons based on RNA-seq studies. WB:WBGene00202246 T24D8.16 No description available WB:WBGene00202247 F46E10.17 Is affected by ifo-1 and lpd-3 based on microarray and RNA-seq studies. WB:WBGene00202248 C47A10.15 No description available WB:WBGene00202249 F23B12.11 No description available WB:WBGene00202250 R13A1.17 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00202251 C52G5.12 No description available WB:WBGene00202252 Y69H2.25 No description available WB:WBGene00202253 Y43H11AL.8 Is affected by eat-2 based on microarray studies. WB:WBGene00202254 ZK381.60 Is affected by cep-1 and adr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202255 F36D1.22 No description available WB:WBGene00202256 ZK863.12 No description available WB:WBGene00202257 C02C6.12 No description available WB:WBGene00202258 F19D8.8 No description available WB:WBGene00202259 ZK973.25 Is affected by sams-3 based on RNA-seq studies. WB:WBGene00202260 H01G02.14 No description available WB:WBGene00202261 F52E1.16 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00202262 T12C9.10 No description available WB:WBGene00202263 C01F4.9 Enriched in neurons based on RNA-seq studies. WB:WBGene00202264 ZK617.24 No description available WB:WBGene00202265 F49E10.25 Is affected by klf-1 based on RNA-seq studies. WB:WBGene00202266 C29E6.17 No description available WB:WBGene00202267 C16E9.28 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202268 F11D5.32 Is affected by adr-1 and nfki-1 based on RNA-seq studies. WB:WBGene00202269 F23H12.20 No description available WB:WBGene00202270 T03F7.15 No description available WB:WBGene00202271 W02G9.9 Is affected by pmt-2 and pptr-1 based on microarray and RNA-seq studies. WB:WBGene00202272 F28E10.15 No description available WB:WBGene00202273 C46C2.12 Is affected by cep-1 and mrps-5 based on RNA-seq studies. WB:WBGene00202274 T11F9.29 No description available WB:WBGene00202275 K07E12.8 No description available WB:WBGene00202276 F40F4.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00202277 Y37F4.14 No description available WB:WBGene00202278 T18D3.14 Is affected by adr-1 and lbp-3 based on RNA-seq studies. WB:WBGene00202279 T02E9.27 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00202280 Y108G3AL.9 No description available WB:WBGene00202281 ZK792.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202282 K09A9.11 No description available WB:WBGene00202283 T06H11.21 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00202284 T28A11.24 No description available WB:WBGene00202285 T04C4.2 No description available WB:WBGene00202286 F12A10.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00202287 F49E10.26 Enriched in neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00202288 W03C9.11 No description available WB:WBGene00202289 F52B10.22 Enriched in neurons based on RNA-seq studies. WB:WBGene00202290 ZC53.21 No description available WB:WBGene00202291 C32A9.6 No description available WB:WBGene00202292 C25F6.28 No description available WB:WBGene00202293 R02D5.23 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00202294 C54G7.16 Is affected by cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00202295 F37D6.12 No description available WB:WBGene00202296 F47F6.15 No description available WB:WBGene00202297 C50B8.8 No description available WB:WBGene00202298 Y49E10.35 No description available WB:WBGene00202299 F37A4.10 Enriched in sensory neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00202300 C01G6.13 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00202301 F35G2.21 Is affected by daf-2 and pmt-2 based on microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202302 C25F6.29 Is affected by dpy-21 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202303 W07G1.22 No description available WB:WBGene00202304 F31F6.16 Is affected by elli-1 based on microarray studies. WB:WBGene00202305 C40H1.13 No description available WB:WBGene00202306 K04B12.8 No description available WB:WBGene00202307 ZK643.13 Is affected by daf-2 based on microarray studies. WB:WBGene00202308 M70.13 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00202309 Y40H7A.309 No description available WB:WBGene00202310 T02E9.28 Enriched in neurons based on RNA-seq studies. WB:WBGene00202311 R10E12.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202312 F59E12.14 No description available WB:WBGene00202313 BE10.7 Enriched in sensory neurons based on RNA-seq studies. Is affected by daf-2 and set-2 based on microarray and RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202314 C06E4.21 No description available WB:WBGene00202315 F29F11.19 Is affected by set-2 based on RNA-seq studies. WB:WBGene00202316 K02G10.14 Is affected by daf-2 based on microarray studies. WB:WBGene00202317 B0350.84 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202318 ZK381.61 No description available WB:WBGene00202319 C36F7.26 No description available WB:WBGene00202320 K01A6.21 No description available WB:WBGene00202321 K01A11.8 Enriched in neurons based on RNA-seq studies. Is affected by alh-4 based on RNA-seq studies. WB:WBGene00202322 T23G5.11 No description available WB:WBGene00202323 Y82E9BR.30 No description available WB:WBGene00202324 Y57G7A.13 No description available WB:WBGene00202325 C18C4.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00202326 F43B10.5 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00202327 R03H4.11 Is affected by dpy-21; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00202328 T04F8.15 No description available WB:WBGene00202329 C05C9.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00202330 C26B9.10 No description available WB:WBGene00202331 C27A12.12 Is affected by daf-2 based on microarray studies. WB:WBGene00202332 C05B10.21 Enriched in neurons based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202333 Y15E3A.15 No description available WB:WBGene00202334 C29E4.18 No description available WB:WBGene00202335 K11G9.14 No description available WB:WBGene00202336 F55C12.18 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202337 F35A5.14 No description available WB:WBGene00202338 F22B3.21 Enriched in neurons based on RNA-seq studies. WB:WBGene00202339 T05B11.13 Is affected by Cry5B and silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202340 C54D2.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202341 ZK783.8 Is affected by daf-2 based on microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202342 ZK617.25 No description available WB:WBGene00202343 F39D8.7 Is affected by several genes including pgl-1; glh-1; and pgl-3 based on RNA-seq studies. WB:WBGene00202344 Y59A8B.38 No description available WB:WBGene00202345 F11D5.33 No description available WB:WBGene00202346 Y105E8B.14 Enriched in AFD based on RNA-seq studies. WB:WBGene00202347 T01H10.10 No description available WB:WBGene00202348 K02E2.16 No description available WB:WBGene00202349 T01A4.6 Is affected by several genes including cep-1; let-418; and dlc-1 based on RNA-seq studies. WB:WBGene00202350 F01G12.17 Enriched in head mesodermal cell based on RNA-seq studies. WB:WBGene00202351 K06C4.26 Is affected by daf-2 based on microarray studies. WB:WBGene00202352 T19D7.11 No description available WB:WBGene00202353 C18H9.11 No description available WB:WBGene00202354 Y46E12A.12 No description available WB:WBGene00202355 M176.15 Is affected by mrpl-2 based on RNA-seq studies. WB:WBGene00202356 F07A11.14 Is affected by adr-1 and adr-2 based on RNA-seq studies. WB:WBGene00202357 F12D9.18 No description available WB:WBGene00202358 C09H10.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202359 Y95B8A.17 No description available WB:WBGene00202360 C28F5.8 No description available WB:WBGene00202361 ZK596.5 Is affected by several genes including daf-2; eat-2; and lem-2 based on RNA-seq and microarray studies. WB:WBGene00202362 Y51H7C.40 No description available WB:WBGene00202363 ZK262.18 No description available WB:WBGene00202364 T24A11.11 No description available WB:WBGene00202365 F21C3.10 Is affected by daf-2 based on microarray studies. WB:WBGene00202366 K01D12.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00202367 R11E3.17 No description available WB:WBGene00202368 D1081.18 No description available WB:WBGene00202369 F28D9.5 Is affected by jmjd-5 based on RNA-seq studies. WB:WBGene00202370 ZK377.13 No description available WB:WBGene00202371 F28D1.22 No description available WB:WBGene00202372 Y105C5B.1417 No description available WB:WBGene00202373 C01F1.8 No description available WB:WBGene00202374 T01C8.11 Is affected by ins-11 based on RNA-seq studies. WB:WBGene00202375 R05G6.19 Enriched in neurons based on RNA-seq studies. WB:WBGene00202376 F28F9.16 No description available WB:WBGene00202377 C14F11.33 Is affected by met-2 based on RNA-seq studies. WB:WBGene00202378 F37B12.14 Is affected by adr-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00202379 C54G7.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00202380 F13C5.10 No description available WB:WBGene00202381 C08E8.14 No description available WB:WBGene00202382 F02C12.10 No description available WB:WBGene00202383 R153.9 Is affected by several genes including daf-2; cep-1; and dpy-21 based on RNA-seq and microarray studies. WB:WBGene00202384 Y53C10A.23 Is affected by cep-1 and nfki-1 based on RNA-seq studies. WB:WBGene00202385 Y73B6BL.287 No description available WB:WBGene00202386 C52B9.18 No description available WB:WBGene00202387 T02E9.29 Is affected by set-2 and camt-1 based on RNA-seq studies. WB:WBGene00202388 C05A9.11 No description available WB:WBGene00202389 Y47D3B.24 Is affected by nhr-86 based on RNA-seq studies. Is affected by sodium arsenite based on RNA-seq studies. WB:WBGene00202390 C31H1.98 No description available WB:WBGene00202391 C34H3.23 No description available WB:WBGene00202392 cTel79B.2 No description available WB:WBGene00202393 R11B5.12 No description available WB:WBGene00202394 T10B9.13 Is affected by cep-1 and hmg-4 based on RNA-seq studies. Is affected by Cry5B and silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202395 B0034.17 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00202396 Y22D7AL.19 No description available WB:WBGene00202397 ZK377.14 No description available WB:WBGene00202398 R09E10.16 Is affected by daf-2 based on RNA-seq studies. WB:WBGene00202399 T22E6.1 Enriched in neurons based on RNA-seq studies. WB:WBGene00202400 C27D6.14 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; hpl-2; and spc-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00202401 F53B3.12 No description available WB:WBGene00202402 Y69H2.26 No description available WB:WBGene00202403 Y67D8C.21 Enriched in neurons based on RNA-seq studies. WB:WBGene00202404 T19D2.11 Is affected by spr-5 based on RNA-seq studies. Is affected by Cry5B based on microarray studies. WB:WBGene00202405 C10G11.17 Is affected by pmt-2 based on microarray studies. WB:WBGene00202406 C07A12.16 No description available WB:WBGene00202407 M02F4.12 Is affected by daf-2; met-2; and spr-5 based on microarray and RNA-seq studies. WB:WBGene00202408 Y23H5B.13 Is affected by cep-1 and adr-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202409 B0273.114 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202410 F54F12.5 No description available WB:WBGene00202411 F11D5.34 No description available WB:WBGene00202412 Y54G2A.71 No description available WB:WBGene00202413 R05H11.5 No description available WB:WBGene00202414 F10C1.20 Is affected by daf-2 based on microarray studies. WB:WBGene00202415 F42A9.15 No description available WB:WBGene00202416 Y16B4A.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00202417 E01H11.6 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1; met-2; and spr-5 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies. WB:WBGene00202418 F41D9.15 No description available WB:WBGene00202419 C02F4.11 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00202420 F53B6.12 No description available WB:WBGene00202421 C14F11.34 Is affected by eat-2 based on microarray studies. WB:WBGene00202422 K08B4.43 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202423 ZK867.23 Is affected by set-2; etr-1; and hlh-26 based on RNA-seq studies. WB:WBGene00202424 T14E8.7 Enriched in AVK based on RNA-seq studies. Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00202425 T24D8.17 Is affected by ikb-1 based on RNA-seq studies. WB:WBGene00202426 C36C9.9 No description available WB:WBGene00202427 T11F9.30 No description available WB:WBGene00202428 E01F3.3 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00202429 C16E9.29 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00202430 C47G2.22 No description available WB:WBGene00202431 F29C4.12 Is affected by daf-2 based on microarray studies. WB:WBGene00202432 Y41C4A.28 Enriched in neurons based on RNA-seq studies. WB:WBGene00202433 K11E4.11 No description available WB:WBGene00202434 K03C7.15 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202435 Y51A2D.38 No description available WB:WBGene00202436 T21H3.10 No description available WB:WBGene00202437 Y15E3A.16 No description available WB:WBGene00202438 Y51H7D.2 No description available WB:WBGene00202439 F46B6.18 Enriched in AVK based on RNA-seq studies. WB:WBGene00202440 C32A3.7 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00202441 F35C12.6 Is affected by set-2 and etr-1 based on RNA-seq studies. WB:WBGene00202442 R05G6.20 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00202443 C13G3.11 No description available WB:WBGene00202444 Y65B4BR.11 No description available WB:WBGene00202445 K11D9.8 Is affected by cep-1; chd-3; and let-418 based on RNA-seq studies. WB:WBGene00202446 F25F2.6 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00202447 T27B1.9 No description available WB:WBGene00202448 C02D4.16 Enriched in AFD based on RNA-seq studies. WB:WBGene00202449 C10H11.14 No description available WB:WBGene00202450 F42D1.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00202451 ZC64.17 No description available WB:WBGene00202452 C32E12.8 No description available WB:WBGene00202453 C30C11.13 Enriched in sensory neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00202454 Y40C7B.10 No description available WB:WBGene00202455 Y25C1A.15 No description available WB:WBGene00202456 C11E4.17 No description available WB:WBGene00202457 F02E8.12 Enriched in neurons based on RNA-seq studies. Is affected by alg-1 based on RNA-seq studies. WB:WBGene00202458 C33D12.17 No description available WB:WBGene00202459 T09B9.9 No description available WB:WBGene00202460 K08A8.31 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00202461 F47E1.16 Is affected by daf-2 based on microarray studies. WB:WBGene00202462 F56F11.7 Is affected by ifo-1 based on microarray studies. WB:WBGene00202463 F28A12.8 Is affected by cep-1; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202464 C07A12.17 No description available WB:WBGene00202465 W01A11.20 Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202466 C08E8.15 Is affected by daf-2 based on microarray studies. WB:WBGene00202467 C06A8.17 No description available WB:WBGene00202468 F26A10.27 No description available WB:WBGene00202469 DY3.12 No description available WB:WBGene00202470 R08B4.15 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; daf-2; and mrps-5 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202471 B0198.10 Enriched in neurons based on RNA-seq studies. Is affected by pgrn-1 based on RNA-seq studies. WB:WBGene00202472 F57G12.15 No description available WB:WBGene00202473 F25F6.4 No description available WB:WBGene00202474 C43D7.19 No description available WB:WBGene00202475 C33F10.24 No description available WB:WBGene00202476 C08F8.14 No description available WB:WBGene00202477 F35C11.13 No description available WB:WBGene00202478 ZK930.13 Is affected by mrps-5 and hlh-26 based on RNA-seq studies. WB:WBGene00202479 R05F9.15 Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00202480 ZK829.13 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00202481 C05E11.18 No description available WB:WBGene00202482 F11D5.35 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00202483 F26G1.14 Is affected by cep-1; daf-2; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00202484 C45B2.19 Is affected by met-2 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202485 F31B9.6 No description available WB:WBGene00202486 K03A11.9 No description available WB:WBGene00202487 T23F11.10 Is affected by daf-2; eat-2; and lag-1 based on microarray and RNA-seq studies. WB:WBGene00202488 ZC190.16 Is affected by alg-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00202489 R06C1.14 No description available WB:WBGene00202490 F28A12.9 Is affected by cep-1; elli-1; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00202491 F55B11.132 Is affected by hmg-3 based on RNA-seq studies. WB:WBGene00202492 T15B7.19 No description available WB:WBGene00202493 T06F4.21 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00202494 F53G12.17 Is affected by cep-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00202495 T26H5.11 Enriched in intestine based on RNA-seq studies. Is affected by spt-16; hpx-2; and csr-1 based on RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00202496 R02F11.9 Predicted to be located in membrane. WB:WBGene00202497 R02F11.10 Predicted to be located in membrane. WB:WBGene00202498 Y60C6A.2 Is affected by several genes including daf-2; elt-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by seven chemicals including tryptophan; allantoin; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00202499 B0507.15 Enriched in neurons based on RNA-seq studies. Is affected by several genes including lin-35; isp-1; and lin-15B based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00202500 K09H11.15 Is affected by smo-1 and sir-2.1 based on proteomic and microarray studies. WB:WBGene00202501 Y57E12B.10 Is affected by several genes including let-418; qui-1; and pmt-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00202502 F41B5.12 Is affected by Ketamine based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00202503 let-75 Is affected by several genes including hpl-2; mut-16; and pry-1 based on microarray; RNA-seq; and proteomic studies. WB:WBGene00202504 Y32B12B.8 Predicted to be located in membrane. WB:WBGene00202505 clk-4 No description available WB:WBGene00202506 clk-5 No description available WB:WBGene00202507 clk-6 No description available WB:WBGene00202508 clk-7 No description available WB:WBGene00202509 clk-9 No description available WB:WBGene00202510 clk-10 No description available WB:WBGene00202511 F07C3.16 Predicted to be located in membrane. WB:WBGene00202512 C25E10.16 Enriched in amphid sheath cell and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; aak-2; and set-2 based on RNA-seq and microarray studies. WB:WBGene00202513 ZK938.10 Predicted to be located in membrane. WB:WBGene00202514 T09F5.20 Predicted to be located in membrane. WB:WBGene00206353 lol-1 No description available WB:WBGene00206354 F27E5.9 Predicted to be located in membrane. WB:WBGene00206355 C34C6.10 Enriched in ASER based on RNA-seq studies. Is affected by several genes including eat-2; aak-2; and smg-2 based on RNA-seq studies. Is affected by tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00206356 T08B2.15 Predicted to enable transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to be located in membrane. WB:WBGene00206357 C09D4.9 Enriched in somatic gonad precursor and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and hsp-6 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00206358 F46E10.18 Enriched in Caapa; intestine; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; Zidovudine; and Rifampin based on RNA-seq studies. WB:WBGene00206359 C05E4.15 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. WB:WBGene00206360 T13C5.10 Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including daf-2; eri-1; and rrf-1 based on microarray and RNA-seq studies. Is affected by single-walled carbon nanotube and allantoin based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282. WB:WBGene00206361 K02G10.15 Enriched in several structures, including ABplapaaaa; ABplppppaa; ABprppppaa; rectal epithelium; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; rrf-3; and hsf-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00206362 B0041.11 Enriched in several structures, including ABalaaaala; AFD; germ line; head neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq studies. Is affected by seven chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00206363 F56H1.10 Predicted to be located in membrane. WB:WBGene00206364 C07A12.18 Predicted to be involved in regulation of cholinergic synaptic transmission and sleep. Predicted to be located in membrane. WB:WBGene00206365 B0563.18 Enriched in neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00206366 C03H5.9 Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. WB:WBGene00206368 Y39F10C.3 Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including tryptophan; iron oxide nanoparticle; and metformin based on microarray and RNA-seq studies. WB:WBGene00206369 C06C6.12 No description available WB:WBGene00206370 F02D8.9 Predicted to be located in membrane. WB:WBGene00206371 F28B12.6 Enriched in Z1; Z4; muscle cell; neurons; and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by six chemicals including multi-walled carbon nanotube; stavudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00206372 B0454.26 Enriched in AFD and in male based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00206373 C27A2.12 Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. WB:WBGene00206374 K10G6.9 Predicted to be located in membrane. WB:WBGene00206375 T08B6.64 Is affected by several genes including cep-1; set-2; and dlc-1 based on RNA-seq studies. WB:WBGene00206377 F44E5.15 Predicted to enable endonuclease activity. WB:WBGene00206378 C14E2.11 Enriched in several structures, including ABaraappaa; ABplapaaapa; ABplapppaa; ABprapaaapa; and ABprapppaa based on single-cell RNA-seq studies. Is affected by several genes including eat-2; tdc-1; and set-2 based on RNA-seq studies. Is affected by metformin and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00206379 C55B6.7 Enriched in GLR based on single-cell RNA-seq studies. WB:WBGene00206380 C42D4.18 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; germ line; and neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00206381 F52H2.15 Predicted to be located in membrane. WB:WBGene00206382 F01G12.18 Predicted to be located in membrane. WB:WBGene00206383 C32C4.16 Predicted to be located in membrane. WB:WBGene00206384 D1005.10 Is affected by several genes including daf-18; kri-1; and unc-70 based on RNA-seq studies. Is affected by four chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00206385 T06D4.6 Enriched in AIML and AIMR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and hda-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00206386 K10C2.12 Enriched in ABalappaap and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq studies. Is affected by ten chemicals including Alovudine; stavudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: Ubiquitin-like domain superfamily; Ubiquitin-like domain; and Ubiquitin family. WB:WBGene00206388 K10C2.14 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00206389 C29F7.10 Enriched in germ line and hypodermis based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and hsf-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00206390 F14F7.7 Enriched in ABplppppap; ABprppppap; B cell; and Y cell based on single-cell RNA-seq studies. Is affected by several genes including nhr-49; atfs-1; and mut-16 based on microarray and RNA-seq studies. Is affected by Rifampin; allantoin; and silicon dioxide nanoparticle based on RNA-seq studies. WB:WBGene00206391 C01B9.7 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00206392 F47D2.11 Predicted to be located in membrane. WB:WBGene00206393 W04G5.16 Predicted to enable kinase activity. Predicted to be involved in phosphorylation. WB:WBGene00206394 W05H5.10 No description available WB:WBGene00206395 C08H9.18 Is affected by adr-1; etr-1; and pals-25 based on RNA-seq studies. WB:WBGene00206411 R13D11.11 Enriched in AVK and head mesodermal cell based on RNA-seq studies. Is affected by seven chemicals including tryptophan; 4-bromodiphenyl ether; and Psoralens based on microarray and RNA-seq studies. WB:WBGene00206412 T24H7.8 Enriched in several structures, including ABalpapaap; ABaraapapp; PLM; RIH; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; hda-1; and mep-1 based on RNA-seq studies. Is affected by six chemicals including mianserin; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00206413 ZK1240.11 Enriched in intestine and muscle cell based on RNA-seq and microarray studies. Is affected by several genes including eat-2; elt-2; and atfs-1 based on RNA-seq and microarray studies. Is affected by Cadmium Chloride; cadmium; and resveratrol based on RNA-seq and microarray studies. WB:WBGene00206414 F31D5.7 Enriched in ABplpaapap; ABprpaapap; amphid sheath cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box protein she-1-like; F-box domain; and Phosphorylation site. WB:WBGene00206415 F59H6.14 Enriched in AFD and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; clk-1; and lin-35 based on microarray and RNA-seq studies. Is affected by Alovudine based on RNA-seq studies. WB:WBGene00206416 W04H10.5 Enriched in GLR; body wall muscle cell; head mesodermal cell; and pharynx based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; dpy-7; and cye-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including multi-walled carbon nanotube; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00206417 W04H10.6 Predicted to be located in membrane. WB:WBGene00206418 M04C3.5 Enriched in AVH; G2; W cell; head mesodermal cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including stavudine; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00206420 T26G10.7 Enriched in germ line and muscle cell based on RNA-seq studies. Is affected by several genes including eat-2; pmk-1; and sek-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00206421 T26G10.8 Is affected by several genes including eat-2; hda-1; and pptr-1 based on RNA-seq studies. WB:WBGene00206422 T26G10.9 Is affected by dpy-21 and pptr-1 based on RNA-seq studies. WB:WBGene00206423 Y41C4A.29 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including prg-1; sma-2; and bcat-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and paraquat based on microarray and RNA-seq studies. WB:WBGene00206459 Y80D4G.1 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; sek-1; and aak-2 based on RNA-seq studies. Is affected by six chemicals including rotenone; metformin; and Sirolimus based on RNA-seq studies. WB:WBGene00206460 F56H9.9 Predicted to be located in membrane. WB:WBGene00206461 Y47D3A.34 Predicted to be located in membrane. WB:WBGene00206462 B0391.14 Enriched in ABalpppppp; ABarpaaa; ABpraaappp; rectal gland cell; and tail precursor cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; dpy-7; and let-418 based on RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00206464 F59C6.18 Enriched in AFD; germ line; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pie-1 based on RNA-seq and microarray studies. Is affected by eighteen chemicals including Zidovudine; allantoin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00206466 T08D10.5 Predicted to be located in membrane. WB:WBGene00206468 ZC262.11 Predicted to be located in membrane. WB:WBGene00206469 F58D2.5 Enriched in several structures, including ABalapapapa; ABalapppapa; ABalppppapa; ABplpaaappa; and mechanosensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and hda-2 based on RNA-seq and microarray studies. Is affected by Rifampin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00206470 F13E9.20 Is affected by eat-2 and rnp-6 based on RNA-seq studies. Is affected by five chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00206471 Y22F5A.11 Enriched in neurons based on RNA-seq studies. Is affected by set-6; baz-2; and egl-43 based on RNA-seq studies. WB:WBGene00206472 bus-24 No description available WB:WBGene00206473 B0273.115 Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and positive regulation of response to oxidative stress. Predicted to be located in membrane. WB:WBGene00206474 T22A3.12 Predicted to be located in motile cilium. WB:WBGene00206475 F27D9.12 Enriched in seam cell based on RNA-seq studies. Is affected by several genes including eat-2; pmk-1; and daf-3 based on RNA-seq studies. Is affected by six chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00206476 Y20F4.9 No description available WB:WBGene00206477 ZC262.12 Predicted to be located in membrane. WB:WBGene00206478 M6.11 Predicted to enable galactoside binding activity. WB:WBGene00206479 C44C11.6 Enriched in intestine based on microarray studies. Is affected by several genes including daf-2; eat-2; and prg-1 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; antimycin; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00206481 Y51B9A.14 Is affected by daf-2; sir-2.1; and daf-16 based on RNA-seq and microarray studies. WB:WBGene00206482 B0416.10 Predicted to enable metal ion binding activity. WB:WBGene00206483 B0416.11 Is affected by several genes including hsf-1; eat-2; and nhr-49 based on RNA-seq and microarray studies. Is affected by eight chemicals including multi-walled carbon nanotube; Sodium Chloride; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00206484 C31H2.14 Enriched in coelomocyte; head mesodermal cell; and neurons based on single-cell RNA-seq and microarray studies. Is affected by several genes including hsf-1; isp-1; and sod-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00206485 C10A4.13 Enriched in AFD and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; daf-12; and eat-2 based on RNA-seq studies. Is affected by seven chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00206486 Y54F10BM.20 Is affected by several genes including eat-2; sin-3; and etr-1 based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00206487 best-19 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00206488 ZK757.10 Enriched in DVA; DVC; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including elt-2; elt-7; and adr-1 based on RNA-seq studies. Is predicted to encode a protein with the following domains: Snake toxin and toxin-like protein; Snake toxin-like superfamily; and Snake toxin/toxin-like. WB:WBGene00206489 F53F1.14 Is affected by several genes including daf-2; rrf-3; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00206490 Y57G11C.1142 Enriched in I6 neuron based on single-cell RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00206491 Y73F8A.1173 Enriched in germ line based on RNA-seq studies. Is affected by several genes including prg-1; atfs-1; and smg-1 based on RNA-seq studies. Is affected by Rifampin; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00206492 F11D11.21 Enriched in seam cell based on RNA-seq studies. Is affected by several genes including tdc-1; meg-3; and tdp-1 based on RNA-seq and microarray studies. WB:WBGene00206493 Y38H8A.12 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including eat-2; lin-35; and aak-2 based on RNA-seq studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00206494 C15H11.16 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by Cry5B; glycine; and CGP37157 based on microarray and RNA-seq studies. WB:WBGene00206495 F20E11.18 No description available WB:WBGene00206496 Y51A2B.16 Predicted to be located in membrane. WB:WBGene00206497 Y52B11A.18 Enriched in AVG based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-35 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00206498 C29A12.22 Predicted to be located in membrane. WB:WBGene00206499 C06H5.11 Is affected by daf-2 and cnd-1 based on microarray and RNA-seq studies. WB:WBGene00206500 F55C9.15 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ABalaapaaa; and ABalaapppa based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; tdc-1; and nhl-2 based on microarray and RNA-seq studies. Is affected by paraquat based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00206501 F14D7.18 Enriched in male based on RNA-seq studies. Is affected by several genes including sir-2.1; unc-30; and adr-1 based on RNA-seq and microarray studies. Is affected by Cry5B and Doxycycline based on microarray and RNA-seq studies. WB:WBGene00206502 T01B7.13 Enriched in hypodermis and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including Tunicamycin; Cry5B; and glycine based on RNA-seq and microarray studies. WB:WBGene00206503 T26E4.18 No description available WB:WBGene00206504 K10G4.15 Is affected by daf-2 based on microarray studies. WB:WBGene00206505 B0250.18 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; xpf-1; and wdr-5.1 based on RNA-seq and microarray studies. Is affected by Cry5B and Sirolimus based on microarray studies. WB:WBGene00206506 F59A1.18 Enriched in male based on RNA-seq studies. Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00206507 Y51A2A.16 Enriched in several structures, including ABalaapppa; ABalapaapa; ABalapppaa; MC neuron; and accessory cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00206508 ZK262.19 Predicted to be located in membrane. WB:WBGene00206509 Y102A5C.43 Is affected by several genes including hsp-6; unc-30; and hpl-2 based on RNA-seq studies. Is affected by Colistin based on microarray studies. WB:WBGene00206510 Y113G7A.22 Enriched in AFD and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00206511 W02H5.16 Predicted to be located in membrane. WB:WBGene00206512 Y39A3B.7 Enriched in neurons based on RNA-seq studies. Is affected by several genes including skn-1; dpy-7; and nhr-49 based on RNA-seq studies. Is affected by seven chemicals including deoxynivalenol; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00206513 B0244.15 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00206514 R05G9.5 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by sacy-1; hda-2; and etr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00206515 T28C6.11 Enriched in several structures, including ABalpapaap; MSpppaaa; excretory cell; head mesodermal cell; and rectal epithelial cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including sir-2.1; pmk-1; and atf-7 based on RNA-seq and microarray studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00206516 F53E4.2 Enriched in arcade cell; neuronal sheath cell; and pharyngeal-intestinal valve cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; csr-1; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00206517 T27F7.12 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; CAN; and pharyngeal cell based on single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and mep-1 based on RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00206518 F36H5.12 Is affected by eat-2 and pmt-2 based on RNA-seq and microarray studies. WB:WBGene00206519 F36H5.13 Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABalpapaap; amphid neurons; and rectal epithelial cell based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including mianserin; multi-walled carbon nanotube; and bisphenol A based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00206520 ZK897.10 Enriched in intestine based on single-cell RNA-seq studies. Is affected by adr-1 and mrps-5 based on RNA-seq and microarray studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00206521 T02G5.15 Enriched in ABaraapapaa; ABaraapppaa; GABAergic neurons; nerve ring neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and sek-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. WB:WBGene00206522 F14D2.19 Enriched in AFD; FLP; head mesodermal cell; and rectal gland cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Psoralens; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Papain-like cysteine peptidase superfamily. WB:WBGene00206523 C54E10.10 Is affected by allantoin and Sirolimus based on RNA-seq studies. WB:WBGene00206524 C54E10.11 Enriched in male based on RNA-seq studies. Is affected by several genes including rrf-3; csr-1; and set-2 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube; iron oxide nanoparticle; and stavudine based on RNA-seq and microarray studies. WB:WBGene00206525 spp-28 Enriched in g2; intestine; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Rifampin; allantoin; and antimycin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Saposin-like. WB:WBGene00206526 C06C3.14 Is affected by several genes including eat-2; lem-2; and emr-1 based on RNA-seq and microarray studies. WB:WBGene00206527 T27A8.7 Enriched in ABplppppap; ABprppppap; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by fzo-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00206528 Y53H1A.7 Enriched in ABplapapppp; ABprapapppp; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; set-2; and qui-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00206529 C04A2.15 Enriched in several structures, including ABaraappaa; MSaaaaapa; MSaapaapa; MSpaaaaa; and pharyngeal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including nhr-49; unc-30; and set-2 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00206530 Y52B11A.19 Enriched in several structures, including ABplpaapap; ABplpapapa; ABplppppap; ABprpaapap; and ABprpapapa based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including lin-35; lin-15B; and met-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00206531 C29F7.11 Enriched in neurons based on RNA-seq studies. Is affected by several genes including set-2; hda-2; and etr-1 based on RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Alovudine; and stavudine based on RNA-seq studies. WB:WBGene00206532 F11A6.15 Enriched in neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and elt-2 based on RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00206533 C30A5.16 Enriched in ABarppaapp; ABarpppapp; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; eat-2; and adr-1 based on RNA-seq studies. Is affected by Zidovudine based on RNA-seq studies. WB:WBGene00206534 C31A11.13 Is affected by adr-1 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00206535 M162.15 Is affected by several genes including daf-2; eat-2; and daf-1 based on microarray and RNA-seq studies. Is affected by tryptophan based on microarray studies. WB:WBGene00206536 C14A6.16 Enriched in NSM based on tiling array studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including Lithium Chloride; methylmercuric chloride; and Mercuric Chloride based on microarray and RNA-seq studies. WB:WBGene00206537 spp-30 Is affected by several genes including daf-16; daf-12; and csr-1 based on RNA-seq studies. Is predicted to encode a protein with the following domain: Saposin-like. WB:WBGene00206538 C09G5.13 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; dpy-7; and unc-30 based on RNA-seq studies. Is affected by six chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies. WB:WBGene00215616 W04G3.17 Enriched in CAN based on single-cell RNA-seq studies. Is affected by smg-2 and etr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00219205 R03D7.15 Enriched in neurons based on RNA-seq studies. Is affected by bcat-1 based on RNA-seq studies. WB:WBGene00219206 W05H12.4 Enriched in ABaraapapp; ABaraapppp; intestine; and neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; egl-43; and sin-3 based on RNA-seq and microarray studies. WB:WBGene00219207 C01F6.14 Predicted to be located in membrane. WB:WBGene00219208 B0365.9 Enriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABarppaapa; and anterior hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and pmk-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including stavudine; Zidovudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Chondroitin proteoglycan 4. WB:WBGene00219209 F29F11.20 Enriched in arcade cell; neurons; and pharyngeal-intestinal valve cell based on RNA-seq studies. Is affected by daf-2; set-2; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00219210 Y37H2A.18 Enriched in RIBL; RIBR; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and elt-2 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box A protein FB224 and F-box domain. WB:WBGene00219212 K10G4.16 No description available WB:WBGene00219214 T10B9.14 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00219215 F13B12.15 Is affected by dlc-1; rnp-6; and camt-1 based on RNA-seq studies. WB:WBGene00219216 K08D10.14 Enriched in PLML; PLMR; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by nineteen chemicals including Alovudine; stavudine; and metformin based on RNA-seq and microarray studies. WB:WBGene00219217 C08F8.15 Enriched in CEP; Caapa; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and lin-4 based on microarray and RNA-seq studies. Is affected by sixteen chemicals including multi-walled carbon nanotube; bisphenol A; and bisphenol S based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00219218 Y73B6BL.288 Enriched in ADE sheath cell; germ line; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00219219 mir-5546 Is affected by alg-5 based on RNA-seq studies. Is affected by graphene oxide based on RNA-seq studies. WB:WBGene00219220 mir-5549 Is affected by alg-5 and hrpk-1 based on RNA-seq studies. WB:WBGene00219221 mir-5551 Enriched in neurons based on RNA-seq studies. Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. WB:WBGene00219222 mir-4806 Enriched in neurons based on RNA-seq studies. Is affected by several genes including alg-1; alg-2; and mir-71 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and graphene oxide based on RNA-seq studies. WB:WBGene00219223 mir-4814 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. WB:WBGene00219224 mir-4924 No description available WB:WBGene00219225 mir-4927 Is affected by alg-5 based on RNA-seq studies. WB:WBGene00219226 mir-4929 Is affected by several genes including alg-2; mir-71; and mrps-5 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle based on microarray studies. WB:WBGene00219227 mir-4932 Is affected by alg-2 and nfki-1 based on RNA-seq studies. WB:WBGene00219228 mir-4933 No description available WB:WBGene00219229 mir-4934 Is affected by nfki-1 and alh-4 based on RNA-seq studies. WB:WBGene00219230 mir-4935 No description available WB:WBGene00219231 mir-5545 Is affected by alg-5 based on RNA-seq studies. WB:WBGene00219232 mir-5547 Is affected by alg-1; alg-2; and alg-5 based on RNA-seq studies. WB:WBGene00219233 mir-5552 Is affected by several genes including alg-1; alg-2; and mrps-5 based on RNA-seq studies. WB:WBGene00219234 B0511.17 Is affected by several genes including eat-2; set-2; and tbh-1 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00219235 K03B4.8 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including nhr-49; unc-70; and cnd-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and silicon dioxide nanoparticle based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00219236 K03B4.9 Enriched in AMshL; AMshR; and amphid sheath cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by bisphenol A; paraquat; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00219238 M151.9 Is affected by several genes including daf-2; dpy-10; and pmk-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Doxycycline; paraquat; and tetrabromobisphenol A based on RNA-seq and microarray studies. WB:WBGene00219239 K05F6.14 Enriched in ABalpapaap; ABarappaap; and lateral ganglion based on single-cell RNA-seq studies. Is affected by several genes including daf-2; mir-35; and let-418 based on RNA-seq and microarray studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: F-box domain. WB:WBGene00219241 Y116A8A.150 Is affected by several genes including dlc-1; etr-1; and set-6 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00219242 F56A12.10 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; dpy-21; and his-3 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219243 T23G4.127 Enriched in muscle cell based on RNA-seq studies. Is affected by smg-2 and csr-1 based on RNA-seq studies. WB:WBGene00219244 Y51H4A.938 Enriched in AVJL; AVJR; and arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and xpf-1 based on microarray and RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00219245 mir-2221 Is affected by alg-1; alg-5; and hrpk-1 based on RNA-seq studies. WB:WBGene00219246 mir-2953 Is affected by several genes including alg-1; alg-2; and mir-71 based on RNA-seq studies. WB:WBGene00219247 mir-4807 Is affected by alg-1; alg-2; and alg-5 based on RNA-seq studies. Is affected by graphene oxide based on RNA-seq studies. WB:WBGene00219248 mir-4808 Is affected by alg-5 based on RNA-seq studies. WB:WBGene00219249 mir-4809 Is affected by prg-1; alg-2; and alg-5 based on RNA-seq studies. WB:WBGene00219250 mir-4810.1 Is affected by prg-1 and alg-5 based on RNA-seq studies. Is affected by graphene oxide based on RNA-seq studies. WB:WBGene00219251 mir-4811 Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq and microarray studies. WB:WBGene00219252 mir-4815 Is affected by hrpk-1 based on RNA-seq studies. WB:WBGene00219253 mir-4916 Is affected by glp-4 based on RNA-seq studies. WB:WBGene00219254 mir-4920 Is affected by prg-1 and alg-5 based on RNA-seq studies. WB:WBGene00219255 mir-4921 No description available WB:WBGene00219256 mir-4922.1 Is affected by hrpk-1 based on RNA-seq studies. WB:WBGene00219257 mir-4922.2 Is affected by hrpk-1 based on RNA-seq studies. WB:WBGene00219258 mir-4923.1 Is affected by alg-5 based on RNA-seq studies. WB:WBGene00219259 mir-4923.2 Is affected by alg-5 based on RNA-seq studies. WB:WBGene00219260 mir-4925 Is affected by alg-1; alg-2; and alg-5 based on RNA-seq studies. WB:WBGene00219261 mir-4926 Is affected by mir-71 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00219262 mir-4930 No description available WB:WBGene00219263 mir-4931 Is affected by glp-4 based on RNA-seq studies. WB:WBGene00219264 mir-4936 Is affected by several genes including prg-1; alg-1; and alg-2 based on RNA-seq studies. WB:WBGene00219265 mir-4937 Is affected by several genes including eat-2; prg-1; and alg-5 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube and graphene oxide based on RNA-seq studies. WB:WBGene00219266 mir-4938 Is affected by several genes including alg-1; smg-1; and alg-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies. WB:WBGene00219267 mir-5548 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including sek-1; met-2; and spr-5 based on microarray and RNA-seq studies. Is affected by stavudine based on RNA-seq studies. WB:WBGene00219269 mir-5553 Is affected by alg-5 based on RNA-seq studies. WB:WBGene00219270 mir-5550 Is affected by several genes including daf-2; prg-1; and alg-1 based on RNA-seq and microarray studies. WB:WBGene00219271 F36H5.14 Enriched in head mesodermal cell and intestine based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq studies. Is affected by seven chemicals including stavudine; Zidovudine; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain and MATH domain. WB:WBGene00219272 C17C3.24 Enriched in muscle cell based on RNA-seq studies. Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. Is affected by Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00219274 T25G12.13 Predicted to enable oxidoreductase activity. Predicted to be located in membrane. Is an ortholog of human DHRS7B (dehydrogenase/reductase 7B). WB:WBGene00219275 Y39G10AR.32 Enriched in ABplpppapa; ABprpppapa; AFD; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00219276 suls-1 No description available WB:WBGene00219277 suls-2 No description available WB:WBGene00219278 R09A8.9 Enriched in AFD; SIBDL; SIBDR; SIBVL; and SIBVR based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by atracurium; Tamoxifen; and paraquat based on RNA-seq studies. WB:WBGene00219279 T24D5.11 Is affected by several genes including eat-2; unc-30; and xpf-1 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Doxycycline based on RNA-seq studies. WB:WBGene00219280 C05B5.16 Predicted to be located in membrane. WB:WBGene00219281 K10D3.8 Is affected by daf-2 and nas-38 based on microarray and RNA-seq studies. WB:WBGene00219282 F43G9.21 Predicted to be located in membrane. WB:WBGene00219283 F55H12.7 Enriched in G2 and W cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; elt-2; and nhr-49 based on RNA-seq and microarray studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00219284 C41G7.15 Enriched in g1AL; g1AR; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by spt-16; set-2; and lpd-3 based on RNA-seq studies. WB:WBGene00219285 K07A1.20 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; hda-1; and spr-5 based on RNA-seq and microarray studies. WB:WBGene00219286 C04F12.16 Enriched in amphid sheath cell and in male based on RNA-seq studies. Is affected by several genes including daf-2; glp-1; and hsf-1 based on RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00219287 spex-1 Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; aak-2; and set-2 based on microarray and RNA-seq studies. Is affected by Acrylamide based on microarray studies. WB:WBGene00219288 Y87G2A.25 Predicted to be located in membrane. WB:WBGene00219289 T05C12.15 Enriched in GABAergic neurons and body wall muscle cell from MS lineage based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; elt-2; and sek-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00219290 AH6.17 Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00219291 F35H8.12 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00219292 ZK1320.14 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; his-72; and smg-2 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00219293 B0334.20 Enriched in intestine based on microarray studies. Is affected by several genes including sir-2.1; adr-1; and pals-22 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00219294 F43G6.16 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00219295 C34C12.12 Enriched in ABaraapapaa; ABaraapppaa; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including eat-2; hda-1; and hrde-1 based on RNA-seq studies. Is affected by metformin; Sirolimus; and Doxycycline based on RNA-seq studies. WB:WBGene00219296 C54C6.11 Is affected by several genes including daf-2; eat-2; and hsp-6 based on RNA-seq and microarray studies. Is affected by six chemicals including Rifampin; allantoin; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00219297 T23F11.11 Predicted to be located in membrane. WB:WBGene00219298 F55H2.8 Enriched in GABAergic neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by five chemicals including Rifampin; allantoin; and Tunicamycin based on RNA-seq and microarray studies. WB:WBGene00219299 C01G12.16 Enriched in ABplaapappp; ABpraapappp; and AFD based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; set-2; and nhl-2 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00219300 W10G6.6 Predicted to be located in membrane. WB:WBGene00219301 C44C10.15 Enriched in male based on RNA-seq studies. WB:WBGene00219302 Y43F8B.28 Enriched in AVG; RIM; and command interneuron based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and dlc-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00219303 Y13C8A.4 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; sek-1; and unc-30 based on RNA-seq studies. Is affected by Sirolimus; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00219304 F56D6.16 Enriched in PVR; germ line; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00219306 linc-4 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and isp-1 based on RNA-seq and microarray studies. Is affected by mianserin; stavudine; and paraquat based on RNA-seq studies. WB:WBGene00219307 F56D6.17 Enriched in VA12; head mesodermal cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and eat-2 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00219308 W06G6.20 Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including D-glucopyranose; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00219309 F26F2.13 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by six chemicals including Rifampin; allantoin; and paraquat based on RNA-seq and microarray studies. WB:WBGene00219310 C17E4.19 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; ABalappppaa; and lateral ganglion based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; dpy-7; and daf-3 based on RNA-seq studies. Is affected by eight chemicals including stavudine; Zidovudine; and Sodium Chloride based on RNA-seq and microarray studies. WB:WBGene00219311 Y51A2A.17 No description available WB:WBGene00219312 Y51A2A.18 Is affected by lin-14 and lin-4 based on microarray studies. Is affected by Atrazine based on microarray studies. WB:WBGene00219313 C17E4.20 Enriched in several structures, including ABalaaaarl; ABalaaaarr; AFD; germ line; and lateral ganglion based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including Alovudine; metformin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00219314 C05B5.17 Predicted to be located in membrane. WB:WBGene00219315 F07E5.12 Enriched in ABalaapppa; ABalapaapa; ABalapppaa; and ABplpapppa based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and unc-30 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00219316 F21A3.11 Predicted to enable acid phosphatase activity and metal ion binding activity. Is an ortholog of human ACP7 (acid phosphatase 7, tartrate resistant (putative)). WB:WBGene00219317 F31E3.12 Predicted to be located in membrane. WB:WBGene00219318 R08A2.9 Is affected by hmg-3; unc-30; and egl-9 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219319 H25P06.5 Enriched in ABaraapapp and ABaraapppp based on single-cell RNA-seq studies. Is affected by several genes including aak-2; hda-1; and hrde-1 based on RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Alovudine; and Psoralens based on RNA-seq studies. WB:WBGene00219321 T07H3.10 Enriched in hypodermis based on RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00219322 C33C12.12 Is affected by several genes including glp-1; eat-2; and aak-2 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00219323 nspd-12 Is affected by flr-4; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00219324 F47B8.18 Enriched in DVA and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and ain-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Sodium Chloride; Chlorpyrifos; and Diazinon based on RNA-seq and microarray studies. WB:WBGene00219325 F17C11.22 Enriched in arc ant V; hyp1; and hyp2 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00219326 F36D3.16 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and eat-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1248); Acyl-CoA N-acyltransferase; Domain of unknown function DUF1248; and Phosphorylation site. WB:WBGene00219327 ZK822.9 Is affected by several genes including csr-1; sacy-1; and nhr-42 based on RNA-seq studies. WB:WBGene00219329 K02D10.8 Enriched in ASER; XXXL; XXXR; amphid sheath cell; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and unc-70 based on RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00219330 F18E2.15 Is affected by daf-2 based on microarray studies. WB:WBGene00219331 H25K10.141 Is affected by eat-2 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00219332 Y116A8C.467 Is affected by several genes including daf-2; eat-2; and aak-2 based on microarray and RNA-seq studies. WB:WBGene00219337 T16G1.18 Enriched in ABplppppaa; ABprppppaa; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including egl-43; etr-1; and set-6 based on RNA-seq studies. Is affected by four chemicals including Sirolimus; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00219342 Y57G11C.1143 Is affected by several genes including aak-2; let-418; and aak-1 based on RNA-seq studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00219343 Y17D7C.9 Enriched in AVK; RID; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including eat-2; sek-1; and tph-1 based on RNA-seq and microarray studies. Is affected by Cry5B based on microarray studies. WB:WBGene00219351 Y7A5A.20 Is affected by set-2 based on RNA-seq studies. WB:WBGene00219352 Y7A5A.21 Is affected by skn-1 based on RNA-seq studies. WB:WBGene00219362 ZK470.14 Predicted to be located in membrane. WB:WBGene00219368 F14H12.17 Predicted to be located in membrane. WB:WBGene00219369 R160.10 Predicted to be located in membrane. WB:WBGene00219370 ZK262.20 Enriched in intestine based on RNA-seq studies. WB:WBGene00219371 C03G5.14 Predicted to be located in membrane. WB:WBGene00219373 F01E11.18 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and aak-2 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00219374 C25A11.10 Enriched in ABarppaapp; ABarpppapp; germ line; neurons; and retrovesicular ganglion based on RNA-seq; tiling array; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by eighteen chemicals including D-glucose; stavudine; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00219375 C02B8.12 Enriched in neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-12; and aak-2 based on RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cystine-knot cytokine. WB:WBGene00219376 C28G1.10 Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. WB:WBGene00219377 F47C12.12 Enriched in male-specific anatomical entity and in male based on RNA-seq and microarray studies. Is affected by several genes including rrf-3; nhr-25; and his-72 based on RNA-seq and microarray studies. WB:WBGene00219378 F43G6.17 Predicted to enable histone deacetylase activity. Predicted to be involved in chromatin remodeling. Predicted to be part of histone deacetylase complex. WB:WBGene00219381 C47A10.16 No description available WB:WBGene00219383 Y61B8A.6 Is affected by ints-2 and etr-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: Serpentine type 7TM GPCR chemoreceptor Sri and 7TM GPCR, serpentine chemoreceptor class i (Sri). WB:WBGene00219394 Y48A6C.8 Enriched in DVC; PVPL; PVPR; and RMED based on single-cell RNA-seq studies. Is affected by fog-2; aak-1; and aak-2 based on RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00219395 M199.134 Predicted to be located in membrane. WB:WBGene00219399 Y55F3AM.21 Enriched in several structures, including ABalppppppp; ABplapppapp; ABpraaapppp; anterior arcade cell; and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; elt-2; and aak-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Alovudine; Rifampin; and allantoin based on RNA-seq studies. WB:WBGene00219410 C04C3.14 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00219411 T14G12.11 Enriched in ABplpaapap; ABprpaapap; head mesodermal cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and lin-35 based on RNA-seq studies. Is affected by four chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00219412 ZK381.62 Predicted to be located in membrane. WB:WBGene00219413 Y38F2AL.12 Is affected by several genes including daf-2; fog-2; and daf-3 based on RNA-seq and microarray studies. Is affected by Alovudine and Zidovudine based on RNA-seq studies. WB:WBGene00219414 F14H3.15 Enriched in arcade cell; neurons; pharyngeal-intestinal valve cell; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including eat-2; elt-2; and sek-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00219415 linc-38 Enriched in AQR and PQR based on single-cell RNA-seq studies. Is affected by several genes including npr-1; cep-1; and adr-1 based on RNA-seq studies. WB:WBGene00219416 F23H12.21 Is affected by several genes including set-2; let-418; and hda-2 based on RNA-seq and microarray studies. WB:WBGene00219417 F34H10.9 Is affected by eat-2; ints-5; and tdc-1 based on RNA-seq studies. WB:WBGene00219418 F44D12.19 Enriched in AFD; ALNL; ALNR; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by sir-2.1 based on microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies. WB:WBGene00219420 T19C4.24 Enriched in ABplpppaapa and ABprpppaapa based on single-cell RNA-seq studies. Is affected by several genes including aak-2; unc-70; and aak-1 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00219421 Y66D12A.30 Enriched in neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by hda-1 and etr-1 based on RNA-seq studies. WB:WBGene00219422 Y52B11A.20 Enriched in several structures, including AVD; accessory cell; head mesodermal cell; hyp3; and rectal epithelial cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sma-3 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq studies. WB:WBGene00219423 C23H5.15 Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00219424 Y54G2A.72 Enriched in AFD and DVC based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; mut-16; and egl-43 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00219425 Y54G2A.73 Enriched in AFD; GABAergic neurons; germ line; and head mesodermal cell based on RNA-seq studies. Is affected by several genes including hsf-1; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; Zidovudine; and allantoin based on RNA-seq and microarray studies. WB:WBGene00219434 F54D5.23 Enriched in AFD based on RNA-seq studies. Is affected by several genes including eat-2; csr-1; and set-2 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00219436 C49H3.16 Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular space. WB:WBGene00219437 C50A2.7 Enriched in neurons based on RNA-seq studies. Is affected by smn-1 and cat-2 based on RNA-seq studies. Is predicted to encode a protein with the following domains: PAN-like domain and PAN-3 domain. WB:WBGene00219442 C08F8.16 Is affected by eat-2 and etr-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00219443 Y57G11C.1144 Enriched in ABalaaaala; ABalaapaaa; AIZ; PVR; and arcade cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray and RNA-seq studies. WB:WBGene00219444 Y41E3.461 Is affected by adr-1 and unc-30 based on RNA-seq studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00219445 C06H5.12 Is affected by daf-2 based on microarray studies. WB:WBGene00219446 C06H5.13 Is affected by daf-2 and nhr-49 based on microarray and RNA-seq studies. WB:WBGene00219447 C06H5.14 Is affected by several genes including daf-2; eat-2; and daf-18 based on RNA-seq and microarray studies. Is affected by mianserin; Zidovudine; and cadmium based on RNA-seq studies. WB:WBGene00219448 K12G11.14 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00219449 Y38A10A.11 Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in DNA biosynthetic process. WB:WBGene00219450 F53B6.13 Enriched in AVK; intestinal muscle; and rectal muscle based on RNA-seq and single-cell RNA-seq studies. Is affected by mrps-5 and hda-2 based on RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00219451 F52D2.12 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and hsf-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Zidovudine; bisphenol A; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00219452 F21D9.11 Enriched in several structures, including AVE; SMB; ciliated neurons; rectal epithelial cell; and rectum based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including mianserin; Psoralens; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00219453 linc-97 Is affected by hrpr-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00219454 C26H9A.3 Is affected by set-6; baz-2; and hda-1 based on RNA-seq studies. WB:WBGene00219455 Y43F8B.29 Is affected by several genes including rrf-3; dpl-1; and set-2 based on RNA-seq studies. WB:WBGene00219456 ZK822.10 Enriched in intestine based on RNA-seq studies. Is affected by several genes including mrps-5; etr-1; and his-3 based on RNA-seq studies. WB:WBGene00219458 H21P03.10 No description available WB:WBGene00219460 K09H9.9 Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and unc-30 based on RNA-seq and microarray studies. Is affected by five chemicals including antimycin; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00219476 D1046.16 Predicted to be located in membrane. WB:WBGene00219477 F57G8.14 Is affected by daf-2; sir-2.1; and mrps-5 based on microarray studies. Is affected by adsorbable organic bromine compound and allantoin based on microarray studies. WB:WBGene00219478 Y105C5B.1418 Predicted to be located in membrane. WB:WBGene00219483 Y116F11B.24 Is affected by daf-2; set-2; and mrps-5 based on microarray and RNA-seq studies. WB:WBGene00219489 C10C6.13 Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00219490 Y116A8B.98 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00219491 Y53F4B.62 Enriched in several structures, including ABplpppaapa; ABprpppaapa; AIM; IL1 neuron; and MC neuron based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Alovudine; Zidovudine; and Psoralens based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00219492 Y53F4B.63 Is affected by nuo-6 based on microarray studies. Is affected by six chemicals including Rifampin; Sirolimus; and allantoin based on RNA-seq and microarray studies. WB:WBGene00219493 C18D4.12 Enriched in excretory gland cell; rectal gland cell; and tail hypodermis based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by metformin; Sirolimus; and cadmium based on RNA-seq and microarray studies. WB:WBGene00219497 linc-114 Is affected by bortezomib based on RNA-seq studies. WB:WBGene00219498 Y106G6E.8 Enriched in g1AL; g1AR; and g1P based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lag-1 based on microarray and RNA-seq studies. WB:WBGene00219505 Y52E8A.8 No description available WB:WBGene00219541 eri-11 No description available WB:WBGene00219542 eri-10 No description available WB:WBGene00219543 eri-8 No description available WB:WBGene00219544 C17G1.14 Enriched in AVK based on RNA-seq studies. Is affected by set-2; atp-2; and cox-5B based on RNA-seq studies. Is affected by allantoin and Sirolimus based on RNA-seq studies. WB:WBGene00219545 F41E7.19 No description available WB:WBGene00219546 F41E7.20 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by four chemicals including bortezomib; Doxycycline; and Tamoxifen based on RNA-seq studies. WB:WBGene00219547 T06A10.106 Predicted to be located in membrane. WB:WBGene00219548 JC8.17 Is affected by several genes including cep-1; set-2; and pptr-1 based on RNA-seq studies. WB:WBGene00219549 F59A1.19 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. Is affected by Atrazine based on microarray studies. WB:WBGene00219550 B0035.20 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00219551 K07F5.21 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including daf-2; cep-1; and dlc-1 based on RNA-seq and microarray studies. WB:WBGene00219552 F53F4.25 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00219553 T08G5.19 Is affected by sams-3 and sams-4 based on RNA-seq studies. WB:WBGene00219554 W03D2.11 Is affected by eat-2; hda-2; and cox-5B based on RNA-seq studies. Is affected by Rifampin; Sirolimus; and paraquat based on RNA-seq studies. WB:WBGene00219555 Y46G5A.46 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219556 C04C11.23 Enriched in muscle cell based on RNA-seq studies. Is affected by several genes including cep-1; mdt-15; and etr-1 based on RNA-seq studies. Is affected by D-glucopyranose and Tamoxifen based on RNA-seq studies. WB:WBGene00219557 anr-14 Is affected by several genes including pptr-1; meg-3; and mrps-5 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00219558 anr-12 Is affected by daf-2 based on microarray studies. WB:WBGene00219559 linc-5 Expressed in muscle cell. WB:WBGene00219560 linc-98 Is affected by daf-2 based on microarray studies. WB:WBGene00219561 linc-142 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dlc-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00219562 linc-28 Is affected by set-2 based on RNA-seq studies. WB:WBGene00219563 linc-95 Is affected by several genes including sek-1; set-2; and dlc-1 based on RNA-seq studies. WB:WBGene00219564 linc-102 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 and alh-4 based on RNA-seq studies. WB:WBGene00219565 linc-120 Enriched in AFD based on RNA-seq studies. Is affected by dlc-1; mrps-5; and etr-1 based on RNA-seq studies. WB:WBGene00219566 linc-33 Is affected by adr-1 and etr-1 based on RNA-seq studies. WB:WBGene00219567 linc-164 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00219568 anr-9 No description available WB:WBGene00219569 linc-147 Enriched in AFD; AVK; neurons; and sensory neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219570 linc-82 Enriched in AVK; head mesodermal cell; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by antimycin; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00219571 linc-15 Enriched in AFD and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and cep-1 based on RNA-seq studies. Is affected by five chemicals including bisphenol A; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00219572 linc-146 Enriched in AVK and sensory neurons based on RNA-seq studies. WB:WBGene00219573 anr-30 Enriched in neurons based on RNA-seq studies. Is affected by hsf-1 and npr-8 based on RNA-seq studies. WB:WBGene00219574 linc-54 Is affected by adr-1; ints-4; and xpf-1 based on RNA-seq studies. WB:WBGene00219575 anr-8 Enriched in AFD and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and unc-30 based on RNA-seq studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00219576 anr-13 Is affected by adr-1 and sams-3 based on RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00219577 linc-119 Is affected by ins-11 based on RNA-seq studies. WB:WBGene00219578 linc-141 Enriched in AVK and neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00219579 linc-43 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by cep-1; unc-70; and sacy-1 based on RNA-seq studies. WB:WBGene00219580 linc-18 Is affected by cep-1; daf-2; and rrf-3 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219581 anr-20 Enriched in AVK and neurons based on RNA-seq studies. Is affected by several genes including pptr-1; smn-1; and etr-1 based on RNA-seq studies. WB:WBGene00219582 anr-25 Is affected by fhod-1; alh-4; and etr-1 based on RNA-seq studies. WB:WBGene00219583 anr-43 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00219584 linc-162 Is affected by npr-1 and ikb-1 based on RNA-seq studies. WB:WBGene00219585 linc-170 Is affected by Tunicamycin and Tamoxifen based on RNA-seq studies. WB:WBGene00219586 linc-108 Is affected by sacy-1 and xpf-1 based on RNA-seq studies. Is affected by CGP37157 and atracurium based on RNA-seq studies. WB:WBGene00219587 anr-16 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; sod-2; and atfs-1 based on RNA-seq studies. WB:WBGene00219588 linc-80 Is affected by spr-1 based on RNA-seq studies. WB:WBGene00219589 anr-35 Enriched in MSpaaaaa and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sek-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by six chemicals including rotenone; metformin; and Rifampin based on RNA-seq studies. WB:WBGene00219590 linc-72 Is affected by several genes including hsf-1; cep-1; and hsp-6 based on RNA-seq studies. Is affected by four chemicals including D-glucopyranose; Alovudine; and stavudine based on RNA-seq studies. WB:WBGene00219591 linc-149 Enriched in AVK and neurons based on RNA-seq studies. Is affected by camt-1 and etr-1 based on RNA-seq studies. WB:WBGene00219592 linc-84 Is affected by several genes including daf-2; hsf-1; and nhr-49 based on RNA-seq and microarray studies. Is affected by four chemicals including tert-Butylhydroperoxide; antimycin; and paraquat based on RNA-seq studies. WB:WBGene00219593 anr-15 Is affected by cep-1 and sams-3 based on RNA-seq studies. WB:WBGene00219594 linc-59 Is affected by ikb-1; nfki-1; and jmjd-5 based on RNA-seq studies. WB:WBGene00219596 linc-140 No description available WB:WBGene00219597 anr-11 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00219598 linc-113 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq studies. WB:WBGene00219599 linc-99 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00219600 linc-118 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00219601 linc-129 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219602 linc-151 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; met-2; and cox-5B based on microarray and RNA-seq studies. WB:WBGene00219603 anr-57 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00219604 linc-93 Is affected by met-2 and spr-5 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219605 linc-110 Is affected by mrps-5; unc-30; and etr-1 based on RNA-seq studies. WB:WBGene00219606 linc-133 Enriched in AVK and neurons based on RNA-seq studies. Is affected by daf-2; camt-1; and etr-1 based on microarray and RNA-seq studies. WB:WBGene00219607 anr-7 Enriched in neurons based on RNA-seq studies. Is affected by ins-11 and set-2 based on RNA-seq studies. WB:WBGene00219608 linc-58 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including cep-1; daf-1; and dpy-21 based on RNA-seq studies. WB:WBGene00219609 linc-7 Enriched in germ line; neurons; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; clk-1; and npr-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219610 anr-51 Is affected by unc-70; etr-1; and cox-5B based on RNA-seq studies. WB:WBGene00219611 linc-123 Is affected by several genes including hsf-1; nhr-49; and olrn-1 based on RNA-seq studies. WB:WBGene00219612 linc-153 Enriched in AVK and neurons based on RNA-seq studies. Is affected by several genes including etr-1; swsn-1; and sams-3 based on RNA-seq studies. WB:WBGene00219613 linc-148 Enriched in neurons based on RNA-seq studies. Is affected by unc-70 based on RNA-seq studies. WB:WBGene00219614 linc-105 Is affected by several genes including cep-1; dlc-1; and adr-1 based on RNA-seq studies. WB:WBGene00219615 linc-109 Is affected by several genes including daf-2; sek-1; and sma-2 based on RNA-seq and microarray studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00219616 linc-111 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00219617 linc-25 Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including dpy-21; etr-1; and npr-8 based on RNA-seq studies. WB:WBGene00219618 linc-60 Is affected by ints-4; nfki-1; and camt-1 based on RNA-seq studies. WB:WBGene00219619 linc-76 Is affected by several genes including daf-2; cep-1; and sod-2 based on RNA-seq and microarray studies. Is affected by antimycin and Doxycycline based on RNA-seq studies. WB:WBGene00219620 linc-74 Is affected by ints-4 based on RNA-seq studies. WB:WBGene00219621 anr-46 Is affected by daf-2 and npr-8 based on microarray and RNA-seq studies. WB:WBGene00219622 anr-40 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219623 anr-2 Is affected by several genes including let-418; mrps-5; and cox-5B based on RNA-seq studies. WB:WBGene00219624 linc-62 No description available WB:WBGene00219625 linc-168 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00219626 linc-157 Is affected by adr-1 and ints-5 based on RNA-seq studies. WB:WBGene00219627 anr-3 Enriched in neurons based on RNA-seq studies. WB:WBGene00219628 linc-161 No description available WB:WBGene00219629 linc-87 Is affected by xpf-1 based on RNA-seq studies. WB:WBGene00219630 linc-70 Is affected by several genes including npr-1; kri-1; and etr-1 based on RNA-seq studies. WB:WBGene00219631 anr-37 Is affected by etr-1; cpl-1; and npr-8 based on RNA-seq studies. WB:WBGene00219632 linc-163 Enriched in neurons based on RNA-seq studies. Is affected by alh-4 based on RNA-seq studies. WB:WBGene00219633 anr-55 No description available WB:WBGene00219634 linc-86 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00219635 linc-51 No description available WB:WBGene00219636 linc-81 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including sek-1; cep-1; and met-2 based on RNA-seq studies. Is affected by bisphenol S based on RNA-seq studies. WB:WBGene00219637 linc-124 Enriched in AVK; head mesodermal cell; neurons; and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219638 anr-29 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219639 linc-115 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including set-2; smn-1; and hda-2 based on RNA-seq studies. WB:WBGene00219640 anr-56 No description available WB:WBGene00219641 linc-47 Is affected by several genes including daf-2; sek-1; and unc-30 based on RNA-seq and microarray studies. Is affected by Alovudine and atracurium based on RNA-seq studies. WB:WBGene00219642 anr-52 Is affected by unc-30 and etr-1 based on RNA-seq studies. WB:WBGene00219643 linc-78 No description available WB:WBGene00219644 linc-69 Is affected by ints-5 and etr-1 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00219645 linc-166 Enriched in neurons based on RNA-seq studies. WB:WBGene00219646 linc-89 Enriched in AFD and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and unc-30 based on microarray and RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219647 anr-27 Is affected by daf-2; spc-1; and unc-70 based on microarray and RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219648 linc-67 Is affected by ints-4; unc-30; and alh-4 based on RNA-seq studies. WB:WBGene00219649 linc-55 Expressed in muscle cell. WB:WBGene00219650 linc-56 Enriched in AFD; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including sma-2; sma-4; and hda-2 based on RNA-seq studies. Is affected by Zidovudine based on RNA-seq studies. WB:WBGene00219651 linc-130 Is affected by dlc-1 and nfki-1 based on RNA-seq studies. WB:WBGene00219652 linc-65 Is affected by alh-4 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219653 linc-145 Enriched in neurons based on RNA-seq studies. WB:WBGene00219654 linc-156 Is affected by dlc-1 and set-2 based on RNA-seq studies. WB:WBGene00219655 linc-107 Is affected by several genes including daf-16; skn-1; and daf-12 based on RNA-seq studies. Is affected by stavudine and paraquat based on RNA-seq studies. WB:WBGene00219656 anr-48 Is affected by several genes including dlc-1; etr-1; and prx-5 based on RNA-seq studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00219657 linc-139 Is affected by several genes including dlc-1; sams-3; and cox-5B based on RNA-seq studies. WB:WBGene00219658 anr-21 Is affected by cep-1; cox-5B; and his-3 based on RNA-seq studies. WB:WBGene00219659 anr-36 Enriched in AVK and sensory neurons based on RNA-seq studies. Is affected by several genes including sek-1; cep-1; and set-2 based on RNA-seq studies. Is affected by graphene oxide and cadmium based on RNA-seq studies. WB:WBGene00219660 linc-19 Enriched in FLP and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and tph-1 based on RNA-seq studies. WB:WBGene00219661 linc-45 Enriched in HSN; PVD; anterior spermatheca; and posterior spermatheca based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; tph-1; and cep-1 based on RNA-seq studies. WB:WBGene00219662 linc-134 Enriched in neurons based on RNA-seq studies. Is affected by ints-5; met-2; and etr-1 based on RNA-seq studies. WB:WBGene00219663 anr-10 No description available WB:WBGene00219664 linc-73 Enriched in AVK; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including set-2; unc-70; and adr-1 based on RNA-seq studies. WB:WBGene00219665 linc-101 Enriched in AFD and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and smg-2 based on RNA-seq and microarray studies. WB:WBGene00219666 linc-31 Enriched in AVK and neurons based on RNA-seq studies. Is affected by several genes including etr-1; elli-1; and ints-6 based on microarray and RNA-seq studies. WB:WBGene00219667 linc-66 Enriched in neurons and in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and unc-30 based on RNA-seq and microarray studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00219668 anr-33 Is affected by hsf-1 based on RNA-seq studies. Is affected by CGP37157 based on RNA-seq studies. WB:WBGene00219669 anr-28 Is affected by cep-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00219670 anr-26 Is affected by daf-2 and sin-3 based on microarray and RNA-seq studies. WB:WBGene00219671 anr-4 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219672 anr-54 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; dlc-1; and xpf-1 based on RNA-seq studies. WB:WBGene00219673 linc-96 Is affected by several genes including nhr-49; atfs-1; and nuo-6 based on RNA-seq studies. Is affected by Zidovudine based on RNA-seq studies. WB:WBGene00219674 linc-122 Is affected by set-2 based on RNA-seq studies. WB:WBGene00219675 linc-44 Enriched in AFD based on RNA-seq studies. Is affected by several genes including sek-1; met-2; and spr-5 based on microarray and RNA-seq studies. WB:WBGene00219676 linc-48 Is affected by several genes including daf-2; eat-2; and tph-1 based on microarray and RNA-seq studies. WB:WBGene00219677 anr-17 Enriched in AFD based on RNA-seq studies. WB:WBGene00219678 linc-9 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including unc-30; set-2; and smg-2 based on RNA-seq studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00219679 anr-22 Is affected by swsn-1 and alh-4 based on RNA-seq studies. WB:WBGene00219680 linc-35 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; set-2; and damt-1 based on RNA-seq studies. Is affected by antimycin; atracurium; and paraquat based on RNA-seq studies. WB:WBGene00219681 anr-6 Enriched in AVK based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00219682 linc-50 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00219683 anr-32 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including tph-1; nhr-49; and cep-1 based on RNA-seq studies. Is affected by tert-Butylhydroperoxide and bortezomib based on RNA-seq studies. WB:WBGene00219684 linc-26 Is affected by swsn-1 based on RNA-seq studies. Is affected by Tamoxifen based on RNA-seq studies. WB:WBGene00219685 linc-75 Is affected by daf-2; swsn-1; and sams-3 based on microarray and RNA-seq studies. WB:WBGene00219686 linc-125 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00219687 linc-12 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219688 linc-21 Enriched in anterior spermatheca; germ line; and posterior spermatheca based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; glp-1; and rrf-3 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219689 linc-41 Enriched in CAN; anterior spermatheca; and posterior spermatheca based on single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and tph-1 based on RNA-seq studies. WB:WBGene00219690 linc-10 Enriched in AFD; AVK; and neurons based on RNA-seq studies. Is affected by several genes including rrf-3; tph-1; and cep-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219691 linc-106 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00219692 linc-23 Is affected by daf-2 based on microarray studies. WB:WBGene00219693 linc-144 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 and etr-1 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00219694 linc-36 Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by Doxycycline; Tamoxifen; and paraquat based on RNA-seq studies. WB:WBGene00219695 linc-126 Enriched in AVK and neurons based on RNA-seq studies. Is affected by cep-1; dlc-1; and etr-1 based on RNA-seq studies. WB:WBGene00219696 anr-39 Is affected by several genes including set-2; unc-70; and etr-1 based on RNA-seq studies. WB:WBGene00219697 linc-169 Is affected by several genes including daf-2; fog-3; and set-2 based on microarray and RNA-seq studies. WB:WBGene00219698 linc-92 Is affected by skn-1 and etr-1 based on RNA-seq studies. Is affected by juglone based on RNA-seq studies. WB:WBGene00219699 linc-22 Enriched in head mesodermal cell; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including sek-1; vit-2; and atfs-1 based on RNA-seq studies. Is affected by Zidovudine; bortezomib; and Oligosaccharides based on RNA-seq and microarray studies. WB:WBGene00219700 linc-6 Enriched in AFD; germ line; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by stavudine; Zidovudine; and Doxycycline based on RNA-seq studies. WB:WBGene00219701 anr-34 Enriched in sensory neurons based on RNA-seq studies. Is affected by hsf-1; sek-1; and etr-1 based on RNA-seq studies. WB:WBGene00219702 linc-138 Is affected by several genes including tph-1; mrps-5; and etr-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219703 anr-38 Enriched in AVK based on RNA-seq studies. WB:WBGene00219704 linc-127 No description available WB:WBGene00219705 anr-5 Is affected by several genes including swsn-1; numr-1; and numr-2 based on RNA-seq studies. Is affected by Doxycycline and Tamoxifen based on RNA-seq studies. WB:WBGene00219706 linc-158 Is affected by daf-2 and nfki-1 based on microarray and RNA-seq studies. WB:WBGene00219707 linc-8 Enriched in intestine and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and tph-1 based on RNA-seq studies. Is affected by Zidovudine and paraquat based on RNA-seq studies. WB:WBGene00219708 linc-13 Is affected by several genes including set-2; let-418; and sin-3 based on RNA-seq studies. Is affected by stavudine based on RNA-seq studies. WB:WBGene00219709 linc-37 Is affected by several genes including daf-2; eat-2; and npr-1 based on RNA-seq and microarray studies. Is affected by four chemicals including graphene oxide; stavudine; and tert-Butylhydroperoxide based on RNA-seq studies. WB:WBGene00219710 anr-45 Enriched in neurons and somatic gonad precursor based on RNA-seq studies. Is affected by adr-2 and nfki-1 based on RNA-seq studies. WB:WBGene00219711 anr-49 Is affected by dpy-21; nfki-1; and etr-1 based on RNA-seq studies. WB:WBGene00219712 linc-167 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; adr-1; and sams-3 based on RNA-seq and microarray studies. WB:WBGene00219713 linc-27 Enriched in AFD and neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00219714 linc-3 Is affected by daf-2 based on microarray studies. Is affected by graphene oxide based on RNA-seq studies. WB:WBGene00219715 anr-18 Is affected by cep-1; spr-5; and alh-4 based on RNA-seq studies. WB:WBGene00219716 linc-88 Is affected by set-2 based on RNA-seq studies. WB:WBGene00219717 anr-23 Enriched in neurons based on RNA-seq studies. WB:WBGene00219718 linc-42 Enriched in neurons and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including meg-3; etr-1; and meg-4 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00219719 linc-57 Expressed in muscle cell. WB:WBGene00219720 linc-2 Enriched in AFD and head mesodermal cell based on RNA-seq studies. Is affected by several genes including cep-1; set-2; and let-418 based on RNA-seq studies. Is affected by Tunicamycin based on RNA-seq studies. WB:WBGene00219721 linc-104 Enriched in AVJ; PVN; RID; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including met-2; spr-5; and dlc-1 based on RNA-seq studies. WB:WBGene00219722 linc-154 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00219723 linc-135 Is affected by several genes including daf-2; mett-10; and cox-5B based on RNA-seq and microarray studies. WB:WBGene00219724 linc-100 Is affected by eat-2 based on microarray studies. WB:WBGene00219725 linc-63 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; cep-1; and mut-16 based on RNA-seq and microarray studies. Is affected by Doxycycline and Tamoxifen based on RNA-seq studies. WB:WBGene00219726 linc-116 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including adr-1; mrps-5; and cox-5B based on RNA-seq studies. WB:WBGene00219727 linc-39 Is affected by several genes including rrf-3; set-2; and let-418 based on RNA-seq studies. WB:WBGene00219728 linc-16 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by bortezomib based on RNA-seq studies. WB:WBGene00219729 anr-44 Enriched in AFD based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219730 linc-137 Enriched in neurons based on RNA-seq studies. WB:WBGene00219731 linc-49 Is affected by several genes including dpy-21; hda-2; and etr-1 based on RNA-seq studies. WB:WBGene00219732 linc-112 No description available WB:WBGene00219733 linc-53 Is affected by several genes including nhr-49; cep-1; and rnp-6 based on RNA-seq studies. Is affected by stavudine and Zidovudine based on RNA-seq studies. WB:WBGene00219734 linc-128 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including unc-30; dlc-1; and efa-6 based on RNA-seq studies. WB:WBGene00219735 linc-150 Enriched in neurons based on RNA-seq studies. WB:WBGene00219736 linc-20 Is affected by several genes including cep-1; unc-30; and sma-2 based on RNA-seq studies. WB:WBGene00219737 linc-155 Is affected by alh-4 based on RNA-seq studies. WB:WBGene00219738 anr-1 Is affected by cep-1; daf-2; and sams-4 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219739 linc-136 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00219740 linc-117 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00219741 linc-77 Is affected by several genes including daf-2; eat-2; and swsn-1 based on microarray and RNA-seq studies. WB:WBGene00219742 linc-52 Is affected by ngn-1 and etr-1 based on RNA-seq studies. WB:WBGene00219743 linc-103 Is affected by several genes including skn-1; cep-1; and unc-70 based on RNA-seq studies. Is affected by graphene oxide and paraquat based on RNA-seq studies. WB:WBGene00219744 anr-41 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219745 linc-90 Enriched in AFD and sensory neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00219746 linc-91 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sek-1; cep-1; and lin-29 based on RNA-seq studies. Is affected by antimycin; atracurium; and paraquat based on RNA-seq studies. WB:WBGene00219747 linc-79 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219748 linc-46 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq studies. Is affected by six chemicals including Tunicamycin; Alovudine; and stavudine based on RNA-seq studies. WB:WBGene00219749 linc-30 Enriched in AFD; muscle cell; and neurons based on RNA-seq studies. Is affected by several genes including unc-30; met-2; and set-25 based on RNA-seq studies. WB:WBGene00219750 Y38C1AA.19 Predicted to enable metal ion binding activity. WB:WBGene00219751 anr-24 Is affected by several genes including pqm-1; smg-2; and xpf-1 based on RNA-seq and microarray studies. Is affected by graphene oxide and stavudine based on RNA-seq studies. WB:WBGene00219752 anr-50 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219753 linc-152 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219754 linc-85 Enriched in PQR and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; cep-1; and lin-29 based on RNA-seq and microarray studies. WB:WBGene00219755 linc-17 Is affected by several genes including rrf-3; hsf-1; and tph-1 based on RNA-seq studies. Is affected by Zidovudine based on RNA-seq studies. WB:WBGene00219756 linc-68 Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by graphene oxide based on RNA-seq studies. WB:WBGene00219757 linc-71 Enriched in neurons based on RNA-seq studies. Is affected by kri-1 and mpk-2 based on RNA-seq studies. Is affected by Tunicamycin and Cadmium Chloride based on RNA-seq studies. WB:WBGene00219758 linc-11 Enriched in head mesodermal cell and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; sek-1; and tph-1 based on RNA-seq studies. WB:WBGene00219759 anr-58 Enriched in AFD based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00219760 anr-19 Is affected by cox-5B and nfki-1 based on RNA-seq studies. WB:WBGene00219761 linc-143 Enriched in AFD based on RNA-seq studies. Is affected by dlc-1; daf-2; and sams-3 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219762 linc-159 Enriched in neurons based on RNA-seq studies. Is affected by prg-1 based on RNA-seq studies. WB:WBGene00219763 linc-94 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21; camt-1; and etr-1 based on RNA-seq studies. WB:WBGene00219764 anr-47 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00219765 linc-165 Enriched in neurons based on RNA-seq studies. Is affected by lag-1 based on RNA-seq studies. WB:WBGene00219766 anr-42 Is affected by several genes including adr-1; etr-1; and npr-8 based on RNA-seq studies. WB:WBGene00219767 linc-131 Is affected by dpy-21 and rnp-6 based on RNA-seq studies. WB:WBGene00219768 linc-160 Enriched in neurons based on RNA-seq studies. Is affected by bcat-1 based on RNA-seq studies. WB:WBGene00219769 linc-64 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; nhr-49; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00219770 linc-40 Enriched in FLP and PVD based on single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and npr-1 based on RNA-seq and microarray studies. Is affected by four chemicals including D-glucopyranose; Zidovudine; and paraquat based on RNA-seq studies. WB:WBGene00219771 linc-24 Enriched in FLP and head mesodermal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; cep-1; and sod-2 based on RNA-seq studies. Is affected by graphene oxide and stavudine based on RNA-seq studies. WB:WBGene00219772 anr-53 Is affected by set-2 and etr-1 based on RNA-seq studies. WB:WBGene00219773 linc-32 Is affected by daf-2; meg-3; and meg-4 based on microarray and RNA-seq studies. WB:WBGene00219774 F33A8.12 Enriched in neurons based on RNA-seq studies. Is affected by set-2 based on RNA-seq studies. WB:WBGene00219775 F33A8.13 Is affected by daf-2; eat-2; and camt-1 based on microarray and RNA-seq studies. WB:WBGene00219776 AH9.9 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00219777 AH10.10 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219778 B0025.7 Enriched in germ line based on RNA-seq studies. Is affected by several genes including skn-1; glp-1; and atfs-1 based on RNA-seq studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00219779 B0025.8 Is affected by dpy-21; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by Tunicamycin and Tamoxifen based on RNA-seq studies. WB:WBGene00219780 B0228.10 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; cep-1; and set-2 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219781 B0240.7 No description available WB:WBGene00219782 B0250.19 Is affected by dlc-1; mett-10; and etr-1 based on RNA-seq studies. WB:WBGene00219783 B0285.17 Is affected by dpy-21; daf-2; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00219784 B0348.8 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00219785 B0350.85 Enriched in neurons based on RNA-seq studies. WB:WBGene00219786 B0365.10 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; daf-2; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00219787 B0379.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219788 B0379.13 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00219789 B0511.18 Is affected by cep-1 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00219790 B0524.10 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219791 C01B10.48 Is affected by cep-1 and daf-3 based on RNA-seq studies. WB:WBGene00219792 C01B10.49 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219793 C01F6.15 Enriched in intestine based on microarray studies. Is affected by sir-2.1 based on microarray studies. WB:WBGene00219794 C02C6.13 Enriched in neurons based on RNA-seq studies. WB:WBGene00219795 C02F5.15 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; fzo-1; and sams-3 based on RNA-seq studies. Is affected by Tunicamycin based on RNA-seq studies. WB:WBGene00219796 C03D6.9 Predicted to be located in membrane. WB:WBGene00219797 C04A2.16 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219798 C04F12.17 No description available WB:WBGene00219799 C05A9.12 Enriched in neurons based on RNA-seq studies. WB:WBGene00219800 C05D9.12 Enriched in germ line based on RNA-seq studies. Is affected by several genes including hsf-1; prg-1; and atfs-1 based on RNA-seq and microarray studies. Is affected by metformin; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00219801 C05E4.16 Is affected by rnp-6; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00219803 C06A1.12 Enriched in body wall musculature and germ line based on RNA-seq and microarray studies. Is affected by several genes including dpy-10; hsf-1; and cep-1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Zidovudine; antimycin; and Doxycycline based on RNA-seq and microarray studies. WB:WBGene00219804 C06E7.95 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00219805 C07A12.19 Is affected by prg-1 and fzo-1 based on RNA-seq studies. WB:WBGene00219806 C07E3.17 Is affected by several genes including daf-16; skn-1; and dpy-21 based on RNA-seq studies. WB:WBGene00219807 C07H6.19 Is affected by unc-30 based on RNA-seq studies. WB:WBGene00219808 C09H10.19 No description available WB:WBGene00219809 C09H10.20 Is affected by set-2 based on RNA-seq studies. WB:WBGene00219810 mir-8196.2 Enriched in AFD based on RNA-seq studies. Is affected by several genes including set-2; meg-3; and meg-4 based on RNA-seq studies. WB:WBGene00219811 C12C8.8 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00219812 C13C12.7 No description available WB:WBGene00219813 C14A11.13 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219814 C14A11.14 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219815 C14B9.15 No description available WB:WBGene00219816 C14E2.12 Enriched in DVC; coelomocyte; and excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and cep-1 based on RNA-seq studies. Is affected by Zidovudine and bortezomib based on RNA-seq studies. WB:WBGene00219817 C15A11.10 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00219818 C15F1.15 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219819 C16D2.4 No description available WB:WBGene00219820 C17D12.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00219821 C17D12.18 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including sek-1; set-2; and fzo-1 based on RNA-seq studies. Is affected by Tunicamycin; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00219822 C17H12.36 Is affected by several genes including glp-1; cep-1; and lag-1 based on RNA-seq and microarray studies. WB:WBGene00219823 C18A3.24 Enriched in RID and neurons based on RNA-seq studies. Is affected by unc-39 based on RNA-seq studies. WB:WBGene00219824 C18C4.17 Is affected by several genes including cep-1; car-1; and dpy-21 based on RNA-seq studies. Is affected by Tunicamycin based on RNA-seq studies. WB:WBGene00219825 C18D1.21 No description available WB:WBGene00219826 C18H9.12 Is affected by several genes including daf-2; cep-1; and set-2 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219827 C23G10.12 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219828 C24A1.8 No description available WB:WBGene00219829 C24G6.12 No description available WB:WBGene00219830 C24G7.6 Is affected by spc-1 and etr-1 based on RNA-seq studies. WB:WBGene00219831 C25F6.30 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sek-1; cep-1; and crh-1 based on RNA-seq studies. Is affected by stavudine; Zidovudine; and cadmium based on RNA-seq studies. WB:WBGene00219832 C26B2.14 Is affected by cep-1 and mrps-5 based on RNA-seq studies. WB:WBGene00219833 C26C6.12 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219834 C26C6.13 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219835 C26C6.14 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219836 C26G2.11 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219837 C28D4.17 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00219838 C28H8.14 Enriched in anterior spermatheca; head mesodermal cell; intestine; and posterior spermatheca based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and cep-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Zidovudine; paraquat; and bortezomib based on RNA-seq studies. WB:WBGene00219839 C29F5.11 No description available WB:WBGene00219840 C29F9.15 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by mrps-5 based on microarray studies. WB:WBGene00219841 C30C11.14 Is affected by daf-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00219842 C30C11.15 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 and dpy-21 based on RNA-seq studies. WB:WBGene00219843 C30D11.6 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219844 C30G12.9 No description available WB:WBGene00219845 C32F10.9 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219846 C33E10.11 No description available WB:WBGene00219847 C34E11.20 Is affected by several genes including daf-12; xpf-1; and adr-1 based on RNA-seq studies. WB:WBGene00219848 C34F6.18 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219849 C36C9.10 Enriched in RIS; germ line; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-2; hsf-1; and clk-1 based on RNA-seq and microarray studies. Is affected by graphene oxide; bortezomib; and paraquat based on RNA-seq studies. WB:WBGene00219850 C36E8.11 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00219851 C37C3.16 Enriched in neurons based on RNA-seq studies. WB:WBGene00219852 C41C4.16 Is affected by dlc-1 and etr-1 based on RNA-seq studies. WB:WBGene00219853 C41C4.17 No description available WB:WBGene00219854 C41C4.18 Is affected by prg-1 and hsf-1 based on RNA-seq studies. WB:WBGene00219855 C41C4.19 No description available WB:WBGene00219856 C41C4.20 Is affected by daf-2 and jmjd-1.2 based on microarray and RNA-seq studies. WB:WBGene00219857 C45E1.10 No description available WB:WBGene00219858 C46A5.15 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00219859 C49F5.11 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; nuo-6; and crh-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219860 C51F7.4 Enriched in AFD based on RNA-seq studies. Is affected by cep-1 and rnp-6 based on RNA-seq studies. WB:WBGene00219861 C52D10.131 No description available WB:WBGene00219862 C52G5.13 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00219863 C54G4.16 No description available WB:WBGene00219864 C56G2.20 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; dlc-1; and bcat-1 based on RNA-seq studies. WB:WBGene00219865 C56G2.21 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; dlc-1; and bcat-1 based on RNA-seq studies. WB:WBGene00219866 D1054.23 Is affected by several genes including daf-2; cep-1; and prg-1 based on RNA-seq and microarray studies. WB:WBGene00219867 D2013.13 No description available WB:WBGene00219868 D2021.6 No description available WB:WBGene00219869 D2023.18 No description available WB:WBGene00219870 D2092.15 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on microarray studies. WB:WBGene00219871 E01A2.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219872 E04F6.17 No description available WB:WBGene00219873 EEED8.19 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219874 F01D4.12 No description available WB:WBGene00219875 F01E11.19 Is affected by Oligosaccharides based on microarray studies. WB:WBGene00219876 F01G12.19 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including unc-30; meg-3; and mrps-5 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219877 F02D10.15 No description available WB:WBGene00219878 F02G3.8 Enriched in neurons based on RNA-seq studies. WB:WBGene00219879 F07A11.15 No description available WB:WBGene00219880 F07C4.17 Is affected by set-2 based on RNA-seq studies. WB:WBGene00219881 F08B1.8 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dpy-21; dlc-1; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00219882 F08B6.7 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00219883 F09B9.8 No description available WB:WBGene00219884 F09E10.13 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219885 F09E10.14 Is affected by several genes including kri-1; mrps-5; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00219886 F09E10.15 Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including sek-1; sid-1; and isp-1 based on RNA-seq studies. WB:WBGene00219887 F09E10.16 Is affected by several genes including daf-2; set-2; and adr-2 based on RNA-seq and microarray studies. WB:WBGene00219888 F09G2.14 Is affected by adr-1 and set-2 based on RNA-seq studies. WB:WBGene00219889 F10E9.23 Is affected by mrps-5 based on microarray studies. WB:WBGene00219890 F12A10.13 No description available WB:WBGene00219891 F12F6.20 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219892 F14F3.17 No description available WB:WBGene00219893 F15A8.19 Is affected by dlc-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00219894 F16A11.12 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 and etr-1 based on RNA-seq studies. WB:WBGene00219895 F16A11.13 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219896 F16H9.5 Enriched in neurons based on RNA-seq studies. Is affected by hda-2 based on RNA-seq studies. WB:WBGene00219897 F16H9.6 Enriched in AFD; head mesodermal cell; and neurons based on RNA-seq studies. Is affected by hda-2 and etr-1 based on RNA-seq studies. WB:WBGene00219898 F17C8.13 Is affected by eat-2 and etr-1 based on microarray and RNA-seq studies. WB:WBGene00219899 F17C11.24 Is affected by ints-4 and camt-1 based on RNA-seq studies. WB:WBGene00219900 F17C11.25 No description available WB:WBGene00219901 F18A1.11 No description available WB:WBGene00219902 F18C5.15 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00219903 F18H3.7 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cox-5B based on RNA-seq studies. WB:WBGene00219904 F19C6.12 Enriched in head mesodermal cell and sensory neurons based on RNA-seq studies. Is affected by several genes including set-2; dlc-1; and ins-11 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219905 F19F10.13 Enriched in germ line based on RNA-seq studies. Is affected by several genes including skn-1; unc-30; and prg-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219906 F19G12.14 No description available WB:WBGene00219907 F19H8.7 Is affected by several genes including smn-1; mrps-5; and etr-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219908 F20C5.10 Enriched in germ line based on RNA-seq studies. Is affected by several genes including hsp-6; atfs-1; and xpf-1 based on microarray and RNA-seq studies. Is affected by five chemicals including stavudine; Zidovudine; and antimycin based on RNA-seq studies. WB:WBGene00219909 F20D12.10 Is affected by several genes including dpy-21; adr-1; and mrps-5 based on RNA-seq studies. WB:WBGene00219910 F21F12.2 Enriched in anterior arcade cell; mc3; pm1; and pm2 based on single-cell RNA-seq studies. Is affected by several genes including daf-2; pgl-1; and prg-1 based on RNA-seq and microarray studies. Is affected by five chemicals including rotenone; multi-walled carbon nanotube; and Psoralens based on RNA-seq studies. WB:WBGene00219911 F21F12.3 No description available WB:WBGene00219912 F22H10.10 Is affected by several genes including sek-1; cep-1; and atfs-1 based on RNA-seq studies. Is affected by metformin and paraquat based on RNA-seq studies. WB:WBGene00219913 F23B12.12 No description available WB:WBGene00219914 F25G6.21 No description available WB:WBGene00219915 F26A10.28 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; hsp-6; and atfs-1 based on microarray and RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00219916 F26D10.23 Is affected by several genes including lag-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00219917 F26D10.24 Is affected by several genes including cep-1; prg-1; and lag-1 based on RNA-seq studies. WB:WBGene00219918 F27C1.18 Is affected by several genes including daf-2; clk-1; and isp-1 based on RNA-seq studies. Is affected by antimycin and paraquat based on RNA-seq studies. WB:WBGene00219919 F27D4.10 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219920 F27D4.11 No description available WB:WBGene00219921 F28B1.13 Is affected by set-2 based on RNA-seq studies. WB:WBGene00219922 F28C10.5 Is affected by dpy-21 based on RNA-seq studies. Is affected by Testosterone based on microarray studies. WB:WBGene00219923 F28D9.6 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00219924 F29F11.21 Enriched in neurons based on RNA-seq studies. WB:WBGene00219925 F29G9.19 Is affected by dpy-21; etr-1; and npr-8 based on RNA-seq studies. WB:WBGene00219926 F30A10.16 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219927 F31C3.17 No description available WB:WBGene00219928 F32A5.11 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219929 F32B4.12 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and camt-1 based on RNA-seq studies. WB:WBGene00219930 F32B5.17 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00219931 F33C8.10 Is affected by set-2 based on RNA-seq studies. WB:WBGene00219932 F33E11.7 Enriched in neurons based on RNA-seq studies. Is affected by adr-1; dlc-1; and camt-1 based on RNA-seq studies. WB:WBGene00219933 F35D11.12 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219934 F35F11.4 Is affected by set-2 and etr-1 based on RNA-seq studies. WB:WBGene00219935 F36H1.17 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on microarray studies. WB:WBGene00219936 F37A8.7 Enriched in neurons based on RNA-seq studies. Is affected by cep-1; etr-1; and lpd-3 based on RNA-seq studies. WB:WBGene00219937 F37F2.4 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219938 F38B7.16 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00219939 F38H4.16 Is affected by lin-14 and lin-4 based on microarray studies. WB:WBGene00219940 F39B2.14 Enriched in AVK based on RNA-seq studies. Is affected by cep-1; set-2; and etr-1 based on RNA-seq studies. WB:WBGene00219941 F40F11.6 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by ints-5 and etr-1 based on RNA-seq studies. WB:WBGene00219942 F40H6.8 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; dpy-21; and adr-1 based on RNA-seq studies. WB:WBGene00219943 F41D3.16 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00219944 F41E6.18 Is affected by prg-1; cep-1; and npr-8 based on RNA-seq studies. WB:WBGene00219945 F42A8.4 No description available WB:WBGene00219946 F42H10.17 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00219947 F44A2.13 Is affected by prg-1 based on RNA-seq studies. WB:WBGene00219948 F44E2.12 Is affected by prg-1; sir-2.1; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00219949 F44E5.16 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and lag-1 based on RNA-seq and microarray studies. WB:WBGene00219950 F46A8.13 Enriched in neurons based on single-cell RNA-seq; RNA-seq; and microarray studies. Is affected by several genes including rrf-3; hsf-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Tunicamycin; bisphenol S; and glycine based on RNA-seq and microarray studies. WB:WBGene00219951 F46A9.12 Enriched in neurons based on RNA-seq studies. Is affected by several genes including set-2; spc-1; and hda-2 based on RNA-seq studies. WB:WBGene00219952 F46H6.12 Is affected by dpy-21 and lpd-3 based on RNA-seq studies. WB:WBGene00219953 F47B3.9 No description available WB:WBGene00219954 F47E1.19 Is affected by daf-2 based on microarray studies. WB:WBGene00219955 F48A9.6 Enriched in AFD based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00219956 F48A11.10 Enriched in neurons based on RNA-seq studies. Is affected by cox-5B and sir-2.1 based on RNA-seq and microarray studies. Is affected by tetrabromobisphenol A based on microarray studies. WB:WBGene00219957 F48F5.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00219958 F49E7.5 Is affected by camt-1 based on RNA-seq studies. WB:WBGene00219959 F52D2.14 Is affected by several genes including daf-2; kri-1; and vit-5 based on microarray and RNA-seq studies. WB:WBGene00219960 F52D10.13 No description available WB:WBGene00219961 F52E1.17 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1; set-2; and etr-1 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00219962 F52E10.11 Is affected by dpy-21; adr-1; and set-2 based on RNA-seq studies. WB:WBGene00219963 F52E10.12 No description available WB:WBGene00219964 F52G3.6 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219965 F54A3.11 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00219966 F54E2.7 Is affected by dpy-21 and set-2 based on RNA-seq studies. WB:WBGene00219967 F54E4.17 No description available WB:WBGene00219968 F54F2.13 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00219969 F54F11.6 Enriched in germ line based on RNA-seq studies. Is affected by several genes including set-2; meg-3; and meg-4 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00219970 F54F12.6 No description available WB:WBGene00219971 F54G2.4 Enriched in AVK; RID; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including smg-2; unc-39; and mrps-5 based on RNA-seq studies. WB:WBGene00219972 F55A3.8 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by cep-1; nfki-1; and etr-1 based on RNA-seq studies. WB:WBGene00219973 F55C7.9 Is affected by daf-2 based on microarray studies. WB:WBGene00219974 F55F1.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00219975 F55F3.9 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by met-2 and spr-5 based on RNA-seq studies. WB:WBGene00219976 F55H12.9 Is affected by several genes including daf-2; met-2; and sma-4 based on RNA-seq and microarray studies. Is affected by paraquat and Ketamine based on RNA-seq studies. WB:WBGene00219977 F56A8.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00219978 F56A11.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00219979 F56A12.11 Is affected by several genes including glp-1; cep-1; and lag-1 based on RNA-seq studies. Is affected by glycine and Cadmium Chloride based on RNA-seq studies. WB:WBGene00219980 F56D1.17 No description available WB:WBGene00219981 F57G12.16 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219982 F58B4.12 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219983 F58D5.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; prg-1; and dpy-21 based on RNA-seq studies. Is affected by Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00219984 F58D5.12 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including prg-1; sma-4; and rnp-6 based on RNA-seq studies. Is affected by Zidovudine and antimycin based on RNA-seq studies. WB:WBGene00219985 F58D5.13 Enriched in sensory neurons based on RNA-seq studies. Is affected by nuo-6 and sek-1 based on RNA-seq studies. WB:WBGene00219986 F59A2.7 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00219987 F59C6.19 Enriched in germ line and muscle cell based on RNA-seq studies. Is affected by set-2; lpd-3; and sir-2.1 based on RNA-seq and microarray studies. Is affected by Ethanol based on microarray studies. WB:WBGene00219988 F59G1.14 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219989 H06I04.14 Enriched in muscle cell based on microarray studies. Is affected by four chemicals including resveratrol; Cry5B; and Sirolimus based on microarray and RNA-seq studies. WB:WBGene00219990 H20J18.2 No description available WB:WBGene00219991 H21P03.11 Is affected by prg-1 and alh-4 based on RNA-seq studies. WB:WBGene00219992 H24G06.5 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00219994 H34C03.21 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219995 H36L18.5 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00219996 H40L08.6 Is affected by dpy-21; thoc-5; and lin-29 based on RNA-seq studies. WB:WBGene00219997 K02A6.6 Is affected by unc-70; set-2; and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00219998 K02A11.12 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00219999 K02B9.10 Enriched in neurons based on RNA-seq studies. Is affected by prg-1 and set-2 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00220000 K02F2.11 Enriched in AFD; AVK; intestine; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; hsp-6; and crh-1 based on RNA-seq and microarray studies. WB:WBGene00220001 K02F3.15 Is affected by several genes including cep-1; xpf-1; and adr-1 based on RNA-seq studies. WB:WBGene00220002 K02F6.11 Is affected by daf-2; sftb-1; and set-2 based on microarray and RNA-seq studies. WB:WBGene00220003 K02G10.16 Is affected by prg-1 and cep-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00220004 K03E5.9 Is affected by several genes including daf-2; sma-4; and let-418 based on RNA-seq and microarray studies. Is affected by stavudine; Doxycycline; and paraquat based on RNA-seq studies. WB:WBGene00220005 K04D7.17 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220006 K04F10.9 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including cep-1; sma-2; and sma-4 based on RNA-seq studies. WB:WBGene00220007 K06A4.15 Enriched in intestine based on RNA-seq studies. Is affected by several genes including cep-1; dlc-1; and wdr-5.1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00220008 K07C5.18 Is affected by ints-9 based on RNA-seq studies. WB:WBGene00220009 K07E1.2 Is affected by several genes including cep-1; dpy-21; and smn-1 based on RNA-seq studies. WB:WBGene00220010 K07G5.7 Is affected by several genes including cep-1; sma-4; and dpy-21 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00220011 K08B5.8 Enriched in germ line and neurons based on RNA-seq studies. Is affected by daf-2; eat-2; and set-2 based on microarray and RNA-seq studies. WB:WBGene00220012 K08F11.8 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00220013 K09E10.5 No description available WB:WBGene00220014 K09F5.14 Is affected by cep-1; spr-5; and etr-1 based on RNA-seq studies. WB:WBGene00220015 K09H9.11 Is affected by damt-1 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00220016 K10C3.13 Is affected by several genes including prg-1; set-2; and mrps-5 based on RNA-seq and microarray studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00220017 K10D2.10 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00220018 K10D3.9 Enriched in neurons and somatic gonad precursor based on RNA-seq studies. WB:WBGene00220019 K10D3.10 Enriched in head mesodermal cell and sensory neurons based on RNA-seq studies. Is affected by several genes including hsf-1; cep-1; and smg-2 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00220020 K10F12.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00220021 K10G6.10 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00220022 K10G6.11 Is affected by rnp-6 based on RNA-seq studies. WB:WBGene00220023 K11C4.14 Enriched in AFD and neurons based on RNA-seq and microarray studies. Is affected by prg-1 and dcr-1 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00220024 K11D9.10 Is affected by dpy-21; adr-1; and dlc-1 based on RNA-seq studies. WB:WBGene00220025 K11E8.7 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; dlc-1; and set-2 based on RNA-seq studies. WB:WBGene00220026 M01D1.11 No description available WB:WBGene00220027 M01D7.11 Is affected by prg-1; set-2; and lbp-3 based on RNA-seq studies. WB:WBGene00220028 M03A8.6 Enriched in neurons based on RNA-seq studies. WB:WBGene00220029 M03D4.78 Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; glp-1; and eat-2 based on RNA-seq and microarray studies. WB:WBGene00220030 M03F4.13 Is affected by several genes including unc-70; spc-1; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00220031 M04G7.4 Enriched in neurons based on RNA-seq studies. WB:WBGene00220032 M7.15 Enriched in neurons based on RNA-seq studies. Is affected by camt-1 based on RNA-seq studies. WB:WBGene00220033 M18.11 Is affected by fzo-1 and etr-1 based on RNA-seq studies. WB:WBGene00220034 M57.3 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 based on microarray studies. WB:WBGene00220035 M60.15 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00220036 R07B7.20 Enriched in intestine based on microarray studies. Is affected by sir-2.1 based on microarray studies. WB:WBGene00220037 R07G3.16 Enriched in sensory neurons based on RNA-seq studies. WB:WBGene00220038 R08C7.19 No description available WB:WBGene00220039 R10A10.3 No description available WB:WBGene00220040 R10E11.13 Enriched in germ line based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00220041 R11A5.8 Is affected by several genes including cep-1; dpy-21; and set-2 based on RNA-seq studies. WB:WBGene00220042 R11E3.18 Is affected by several genes including met-2; spr-5; and xpf-1 based on RNA-seq studies. WB:WBGene00220043 R12C12.13 No description available WB:WBGene00220044 R13G10.5 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00220045 R31.6 No description available WB:WBGene00220046 R31.7 Is affected by cep-1 and etr-1 based on RNA-seq studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00220047 R74.11 Is affected by adr-1; dlc-1; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00220048 R106.6 Enriched in AFD; head mesodermal cell; and sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; prg-1; and atfs-1 based on RNA-seq and microarray studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00220049 R106.7 Enriched in head mesodermal cell and sensory neurons based on RNA-seq studies. Is affected by several genes including sek-1; cep-1; and mex-3 based on RNA-seq and microarray studies. Is affected by stavudine and paraquat based on RNA-seq studies. WB:WBGene00220050 R144.18 Is affected by prg-1; cep-1; and mdt-15 based on RNA-seq studies. Is affected by D-glucopyranose based on RNA-seq studies. WB:WBGene00220051 R160.11 Is affected by several genes including daf-2; dlc-1; and adr-1 based on microarray and RNA-seq studies. WB:WBGene00220052 R166.10 Enriched in neurons based on RNA-seq studies. Is affected by adr-1 and etr-1 based on RNA-seq studies. WB:WBGene00220053 R166.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00220054 T01A4.8 Enriched in neurons based on RNA-seq studies. Is affected by met-2 based on RNA-seq studies. WB:WBGene00220055 mir-8196.1 Expressed in head neurons and tail neurons. WB:WBGene00220056 T01C2.6 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220057 T04C9.13 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220058 T05A6.20 Is affected by nfki-1 and etr-1 based on RNA-seq studies. WB:WBGene00220059 T06E4.20 No description available WB:WBGene00220060 T07D3.12 No description available WB:WBGene00220061 T07D4.7 Is affected by several genes including daf-2; glp-1; and lag-1 based on RNA-seq and microarray studies. WB:WBGene00220062 T08D2.11 Enriched in sensory neurons based on RNA-seq studies. Is affected by cep-1; wdr-5.1; and xpf-1 based on RNA-seq studies. WB:WBGene00220063 T08H4.9 No description available WB:WBGene00220064 T09B4.21 Is affected by adr-1 and dlc-1 based on RNA-seq studies. WB:WBGene00220065 T09B4.22 Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00220066 T09B9.10 Is affected by several genes including cep-1; prg-1; and dpy-21 based on RNA-seq studies. WB:WBGene00220067 T12B3.10 Is affected by sir-2.1 based on microarray studies. WB:WBGene00220068 T12D8.12 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00220069 T13E5.1 Is affected by cep-1 based on RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00220070 T14F9.22 No description available WB:WBGene00220071 T15H9.8 Is affected by several genes including cep-1; met-2; and spr-5 based on RNA-seq studies. WB:WBGene00220072 T19C3.11 Enriched in AFD based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00220073 T19E7.29 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and etr-1 based on RNA-seq studies. WB:WBGene00220074 T20B12.12 No description available WB:WBGene00220075 T21B4.20 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00220076 T21B4.21 Is affected by several genes including rrf-3; sek-1; and atfs-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Zidovudine; glycine; and bortezomib based on RNA-seq studies. WB:WBGene00220077 T21C12.12 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; atfs-1; and sma-2 based on RNA-seq studies. WB:WBGene00220078 T21F2.3 Is affected by several genes including set-2; mett-10; and lpd-3 based on RNA-seq studies. WB:WBGene00220079 T21H8.10 No description available WB:WBGene00220080 T21H8.11 No description available WB:WBGene00220081 T22C1.17 Is affected by adr-1 and daf-12 based on RNA-seq studies. WB:WBGene00220082 T22C8.10 No description available WB:WBGene00220083 T23B12.13 No description available WB:WBGene00220084 T23B12.14 Is affected by several genes including skn-1; sir-2.1; and isp-1 based on RNA-seq and microarray studies. Is affected by Alovudine based on RNA-seq studies. WB:WBGene00220085 T23D8.11 Is affected by set-2; ikb-1; and nfki-1 based on RNA-seq studies. WB:WBGene00220086 T23D8.12 Is affected by several genes including gld-1; aak-2; and isp-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Tamoxifen; Hydrolyzable Tannins; and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00220087 T23D8.13 Enriched in head mesodermal cell and neurons based on RNA-seq studies. Is affected by several genes including rrf-3; sek-1; and prg-1 based on RNA-seq studies. Is affected by stavudine and Zidovudine based on RNA-seq studies. WB:WBGene00220088 T23F11.12 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including spr-5; set-2; and hda-2 based on RNA-seq studies. WB:WBGene00220089 T23G11.12 Is affected by several genes including meg-3; etr-1; and meg-4 based on RNA-seq studies. Is affected by Tunicamycin based on RNA-seq studies. WB:WBGene00220090 T24B8.22 Is affected by several genes including daf-2; set-2; and unc-70 based on microarray and RNA-seq studies. WB:WBGene00220091 T24B8.23 Is affected by dlc-1; daf-2; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00220092 T24H10.12 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; dlc-1; and hda-2 based on RNA-seq studies. WB:WBGene00220093 T25C12.11 Enriched in head mesodermal cell; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including skn-1; sek-1; and cep-1 based on RNA-seq studies. Is affected by four chemicals including stavudine; Zidovudine; and paraquat based on RNA-seq studies. WB:WBGene00220094 T25C12.12 Enriched in head mesodermal cell; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including sek-1; prg-1; and atfs-1 based on RNA-seq studies. Is affected by stavudine; Zidovudine; and paraquat based on RNA-seq studies. WB:WBGene00220095 T25D3.8 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00220096 T25D10.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00220097 T25G12.15 Is affected by spr-5 and etr-1 based on RNA-seq studies. WB:WBGene00220098 T26C11.10 Is affected by daf-2 based on microarray studies. WB:WBGene00220099 T26H10.10 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 based on RNA-seq studies. WB:WBGene00220100 T27A3.12 No description available WB:WBGene00220101 T27A8.8 Is affected by daf-2 and lag-1 based on microarray and RNA-seq studies. WB:WBGene00220102 T27C4.7 No description available WB:WBGene00220104 T27E4.22 Is affected by several genes including daf-16; cep-1; and dpy-21 based on RNA-seq studies. WB:WBGene00220105 T27E9.11 Is affected by hda-2 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00220106 T28B8.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00220107 W01A11.21 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220108 W01D2.9 Is affected by several genes including daf-2; set-2; and adr-1 based on RNA-seq and microarray studies. WB:WBGene00220109 W01F3.4 Is affected by several genes including daf-2; daf-12; and prg-1 based on RNA-seq and microarray studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00220110 W01F3.5 Is affected by several genes including daf-2; daf-12; and prg-1 based on RNA-seq and microarray studies. WB:WBGene00220111 W01H2.11 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00220112 W02B9.3 Is affected by dlc-1 and mrps-5 based on RNA-seq studies. WB:WBGene00220113 W02C12.4 Enriched in sensory neurons based on RNA-seq studies. Is affected by dlc-1 and etr-1 based on RNA-seq studies. WB:WBGene00220114 W02H5.17 Is affected by several genes including dpy-21; set-2; and dlc-1 based on RNA-seq and microarray studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00220115 W02H5.18 Is affected by cep-1 and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00220116 W03A5.8 Enriched in intestine based on RNA-seq studies. Is affected by unc-70 and ints-4 based on RNA-seq studies. Is affected by Ketamine based on RNA-seq studies. WB:WBGene00220117 W03B1.17 Is affected by several genes including cep-1; set-2; and wdr-23 based on RNA-seq studies. WB:WBGene00220118 W03D8.13 Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq and microarray studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00220119 W04D12.2 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and cep-1 based on RNA-seq and microarray studies. WB:WBGene00220120 W05G11.7 No description available WB:WBGene00220121 W06A7.12 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dlc-1; ints-4; and etr-1 based on RNA-seq studies. WB:WBGene00220122 W06D12.9 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00220123 W06H8.16 Is affected by cox-5B; dlc-1; and etr-1 based on RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00220124 W06H8.17 Is affected by etr-1 based on RNA-seq studies. Is affected by Oligosaccharides based on microarray studies. WB:WBGene00220125 W07G1.23 Is affected by ints-5; meg-3; and meg-4 based on RNA-seq studies. WB:WBGene00220126 W10C8.17 Is affected by cep-1; dlc-1; and mrps-5 based on RNA-seq studies. WB:WBGene00220127 W10D5.5 Enriched in neurons based on RNA-seq studies. WB:WBGene00220128 Y6B3B.15 Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00220129 Y10G11A.91 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00220130 Y10G11A.92 No description available WB:WBGene00220131 Y11D7A.21 Is affected by several genes including sir-2.1; cep-1; and set-2 based on RNA-seq and microarray studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00220132 Y11D7A.22 No description available WB:WBGene00220133 Y14H12A.4 Is affected by several genes including prg-1; set-2; and hda-2 based on RNA-seq studies. Is affected by Zidovudine; Doxycycline; and cadmium based on RNA-seq studies. WB:WBGene00220134 Y17G7B.25 Is affected by cep-1; dpy-21; and prx-5 based on RNA-seq studies. WB:WBGene00220135 Y18D10A.29 Enriched in neurons based on RNA-seq studies. WB:WBGene00220136 Y20F4.11 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220137 Y24D9A.13 Is affected by single-walled carbon nanotube and allantoin based on microarray studies. WB:WBGene00220138 Y32F6B.8 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dpy-21 and eat-2 based on RNA-seq and microarray studies. WB:WBGene00220139 Y32G9A.15 Enriched in neurons based on RNA-seq studies. WB:WBGene00220140 Y34F4.7 Is affected by several genes including rrf-3; set-2; and smg-2 based on RNA-seq studies. Is affected by antimycin; CGP37157; and paraquat based on RNA-seq studies. WB:WBGene00220141 Y37E11AR.9 Enriched in neurons based on microarray studies. Is affected by fbf-1; ash-2; and tdp-1 based on microarray studies. Is affected by four chemicals including Humic Substances; Sirolimus; and allantoin based on microarray and RNA-seq studies. WB:WBGene00220142 Y37F4.15 Enriched in head mesodermal cell; neurons; and sensory neurons based on RNA-seq studies. Is affected by several genes including hda-2; mrps-5; and sacy-1 based on RNA-seq and microarray studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00220143 Y38E10A.32 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00220144 Y39A1A.30 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00220145 Y39A3CR.11 Enriched in neurons based on RNA-seq studies. WB:WBGene00220146 Y40A1A.5 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00220147 Y40B1A.6 Enriched in neurons based on RNA-seq studies. Is affected by cep-1 and dlc-1 based on RNA-seq studies. WB:WBGene00220148 Y40B1B.10 No description available WB:WBGene00220149 Y40H7A.310 No description available WB:WBGene00220150 Y41C4A.30 Enriched in neurons based on RNA-seq studies. WB:WBGene00220151 Y41C4A.31 No description available WB:WBGene00220152 Y41D4B.33 Is affected by cep-1; dpy-21; and set-2 based on RNA-seq studies. WB:WBGene00220153 Y41D4B.34 Is affected by several genes including dpy-10; fbf-1; and dpy-21 based on RNA-seq and microarray studies. Is affected by paraquat and Sirolimus based on microarray studies. WB:WBGene00220154 Y41D4B.35 Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00220155 Y41D4B.36 Is affected by Ketamine based on RNA-seq studies. WB:WBGene00220156 Y41E3.463 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220157 Y41E3.464 Is affected by cadmium based on RNA-seq studies. WB:WBGene00220158 Y41G9A.16 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220159 Y44A6C.3 Enriched in neurons based on RNA-seq studies. Is affected by several genes including cep-1; dpy-21; and adr-1 based on RNA-seq studies. WB:WBGene00220160 Y44A6C.4 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21; eat-2; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00220161 Y46E12BL.11 Is affected by prg-1 and vit-5 based on RNA-seq studies. WB:WBGene00220162 Y46E12BM.1 Is affected by set-2 based on RNA-seq studies. Is affected by four chemicals including Microcystin-LR; adsorbable organic bromine compound; and allantoin based on microarray studies. WB:WBGene00220163 Y47D3A.35 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including prg-1; adr-2; and etr-1 based on RNA-seq studies. Is affected by antimycin and graphene oxide based on RNA-seq studies. WB:WBGene00220164 Y47D3B.25 No description available WB:WBGene00220165 Y47G6A.36 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including rrf-3; cep-1; and sma-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including Tunicamycin; paraquat; and Chlorpyrifos based on RNA-seq and microarray studies. WB:WBGene00220166 Y47G6A.37 Enriched in neurons based on RNA-seq studies. Is affected by sir-2.1 based on microarray studies. WB:WBGene00220167 Y47G6A.38 Is affected by ints-4 based on RNA-seq studies. WB:WBGene00220168 Y48A6C.10 Enriched in germ line based on RNA-seq studies. Is affected by several genes including dpy-21; set-2; and meg-3 based on RNA-seq studies. WB:WBGene00220169 Y48B6A.25 Is affected by cep-1 based on RNA-seq studies. Is affected by Tunicamycin based on RNA-seq studies. WB:WBGene00220170 Y48C3A.25 Is affected by several genes including met-2; dpy-21; and spr-5 based on RNA-seq studies. WB:WBGene00220171 Y48G10A.9 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including cep-1; prg-1; and sma-2 based on RNA-seq studies. WB:WBGene00220172 Y49E10.36 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sek-1; dpy-21; and his-72 based on RNA-seq studies. WB:WBGene00220173 Y50D4C.11 No description available WB:WBGene00220174 Y51A2D.40 No description available WB:WBGene00220175 Y51H4A.939 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by cep-1; adr-1; and dlc-1 based on RNA-seq studies. WB:WBGene00220176 Y51H4A.940 Enriched in AFD based on RNA-seq studies. WB:WBGene00220177 Y51H7BM.2 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220178 Y52D3.2 Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; dpy-21; and set-2 based on RNA-seq and microarray studies. WB:WBGene00220179 Y54E10A.29 Enriched in neurons based on RNA-seq studies. Is affected by zip-3 based on RNA-seq studies. WB:WBGene00220180 Y54G2A.74 Is affected by cep-1 and etr-1 based on RNA-seq studies. Is affected by metformin based on RNA-seq studies. WB:WBGene00220181 Y55F3AM.23 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00220182 Y55F3BL.5 Is affected by unc-70 based on RNA-seq studies. WB:WBGene00220183 Y55F3BR.19 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 and camt-1 based on RNA-seq studies. WB:WBGene00220184 Y57A10A.44 No description available WB:WBGene00220185 Y57G11C.1145 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00220186 Y57G11C.1146 No description available WB:WBGene00220187 Y62F5A.16 Is affected by cep-1 and adr-1 based on RNA-seq studies. WB:WBGene00220188 Y65B4A.10 Is affected by several genes including daf-2; fbf-1; and fbf-2 based on RNA-seq and microarray studies. WB:WBGene00220189 Y65B4A.11 Is affected by several genes including daf-2; prg-1; and atfs-1 based on RNA-seq and microarray studies. WB:WBGene00220190 Y65B4BM.2 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including skn-1; glp-1; and sek-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Alovudine; Zidovudine; and antimycin based on RNA-seq studies. WB:WBGene00220191 Y65B4BR.12 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220192 Y66H1B.6 No description available WB:WBGene00220193 Y67D2.11 No description available WB:WBGene00220194 Y69E1A.15 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dpy-21 and zip-3 based on RNA-seq studies. WB:WBGene00220195 Y71F9AL.24 Enriched in neurons based on RNA-seq studies. WB:WBGene00220196 Y71G10AR.5 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00220197 Y71G12B.41 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00220198 Y71G12B.42 Is affected by several genes including prg-1; unc-70; and xpo-1 based on RNA-seq studies. Is affected by Tunicamycin; stavudine; and paraquat based on RNA-seq studies. WB:WBGene00220199 Y71H2AM.28 Is affected by several genes including prg-1; set-2; and unc-70 based on RNA-seq studies. WB:WBGene00220200 Y71H2B.12 Is affected by set-2 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00220201 Y73B3A.30 No description available WB:WBGene00220202 Y73B3A.31 No description available WB:WBGene00220203 Y73B6A.14 Enriched in neurons based on RNA-seq studies. WB:WBGene00220204 Y73B6A.15 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220205 Y73F8A.1175 No description available WB:WBGene00220206 Y75B7AL.9 Is affected by dpy-21 and fzo-1 based on RNA-seq studies. WB:WBGene00220207 Y75B8A.62 Is affected by several genes including sek-1; set-2; and unc-70 based on RNA-seq studies. Is affected by cadmium based on RNA-seq studies. WB:WBGene00220208 Y75B12B.16 Enriched in germ line based on RNA-seq studies. Is affected by cep-1; nfki-1; and fzo-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00220209 Y75D11A.8 Is affected by adr-1 and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00220210 Y76A2B.10 No description available WB:WBGene00220211 Y76B12C.11 Enriched in AFD based on RNA-seq studies. Is affected by several genes including prg-1; atfs-1; and set-2 based on RNA-seq studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00220212 Y76G2B.1 Is affected by daf-2 based on microarray studies. WB:WBGene00220213 Y77E11A.21 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220214 Y79H2A.14 No description available WB:WBGene00220215 Y92C3B.4 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including atfs-1; set-2; and uaf-1 based on RNA-seq studies. WB:WBGene00220216 Y94H6A.15 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00220217 Y95B8A.18 Is affected by daf-2 based on microarray studies. WB:WBGene00220218 Y102A5D.22 No description available WB:WBGene00220219 Y102A11A.16 No description available WB:WBGene00220220 Y102A11A.17 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00220221 Y105C5A.1282 No description available WB:WBGene00220222 Y105C5A.1283 No description available WB:WBGene00220223 Y105C5A.1284 Enriched in germ line based on RNA-seq studies. WB:WBGene00220224 Y105C5B.1419 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. WB:WBGene00220225 Y105E8A.50 Is affected by several genes including daf-2; hsp-6; and atfs-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Zidovudine; antimycin; and Doxycycline based on RNA-seq studies. WB:WBGene00220226 Y105E8B.15 Enriched in AFD based on RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00220227 Y110A2AL.20 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00220228 Y111B2A.34 Is affected by dlc-1 and set-2 based on RNA-seq studies. WB:WBGene00220229 Y111B2A.35 Is affected by daf-2 and rnp-6 based on microarray and RNA-seq studies. WB:WBGene00220230 Y111B2A.36 Is affected by prg-1; rnp-6; and etr-1 based on RNA-seq studies. WB:WBGene00220231 Y119C1B.13 Is affected by lag-1 based on RNA-seq studies. WB:WBGene00220232 ZC334.17 Enriched in neurons based on RNA-seq studies. WB:WBGene00220233 ZC395.12 Is affected by cep-1; ins-11; and mrps-5 based on RNA-seq studies. WB:WBGene00220234 ZC410.9 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00220235 ZC412.15 Enriched in neurons and sensory neurons based on RNA-seq studies. WB:WBGene00220236 ZK20.9 Enriched in AFD and neurons based on RNA-seq studies. Is affected by several genes including set-2; dlc-1; and adr-2 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00220237 ZK20.10 Is affected by fzo-1 based on RNA-seq studies. WB:WBGene00220238 ZK185.9 Is affected by several genes including mir-71; xpf-1; and dlc-1 based on RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00220239 ZK218.23 Is affected by lag-1 and set-2 based on RNA-seq studies. WB:WBGene00220240 ZK270.4 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00220241 ZK270.5 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00220242 ZK328.11 Is affected by rnp-6 based on RNA-seq studies. WB:WBGene00220243 ZK484.11 Enriched in neurons based on RNA-seq studies. Is affected by dpy-21 and ints-4 based on RNA-seq studies. WB:WBGene00220244 ZK632.18 Is affected by cep-1 based on RNA-seq studies. WB:WBGene00220245 ZK816.9 No description available WB:WBGene00220246 ZK858.10 Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq studies. Is affected by five chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00220247 ZK892.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00220248 ZK930.15 Is affected by dpy-21 based on RNA-seq studies. WB:WBGene00220249 R144.19 No description available WB:WBGene00220250 C09B9.85 Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of several human genes including BEST1 (bestrophin 1); BEST2 (bestrophin 2); and BEST3 (bestrophin 3). WB:WBGene00220251 F07C6.8 Is affected by several genes including spc-1; etr-1; and lpd-3 based on RNA-seq studies. WB:WBGene00220252 C02F4.12 Enriched in AVK; neurons; and sensory neurons based on RNA-seq studies. Is affected by adr-1; dlc-1; and alh-4 based on RNA-seq studies. WB:WBGene00220253 C05A2.4 Enriched in pharynx based on RNA-seq studies. Is affected by several genes including eat-2; dpy-21; and mrps-5 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00220254 Y105C5A.1285 No description available WB:WBGene00220255 Y39B6A.83 No description available WB:WBGene00220256 Y39B6A.84 No description available WB:WBGene00220257 C02H6.3 Predicted to be located in membrane. WB:WBGene00220258 C50C3.19 Enriched in AFD; RID; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on microarray and RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00220259 ZK418.13 Predicted to be located in membrane. WB:WBGene00220260 Y105C5B.1420 Is affected by several genes including daf-2; rrf-3; and hsp-6 based on microarray and RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00220261 ZC434.10 Enriched in PLM and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by six chemicals including Zidovudine; antimycin; and glycine based on RNA-seq and microarray studies. WB:WBGene00235003 F26F2.15 Is affected by smg-2 based on RNA-seq studies. Is affected by Rifampin; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00235080 mir-5592.1 Is affected by eat-2 and hrpk-1 based on RNA-seq studies. WB:WBGene00235081 W06G6.21 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by etr-1; ain-1; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00235084 mir-5594 Is affected by alg-5 based on RNA-seq studies. WB:WBGene00235085 mir-5592.2 Is affected by eat-2 and hrpk-1 based on RNA-seq studies. WB:WBGene00235086 T04C12.32 Is affected by several genes including eat-2; cep-1; and etr-1 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00235087 mir-5593.1 No description available WB:WBGene00235088 mir-5593.2 No description available WB:WBGene00235089 F46B3.24 Is affected by resveratrol based on microarray studies. WB:WBGene00235090 C38D9.13 Is affected by several genes including daf-2; eat-2; and clk-1 based on RNA-seq studies. Is affected by four chemicals including Alovudine; Rifampin; and Psoralens based on RNA-seq studies. WB:WBGene00235091 T08G3.15 Is affected by daf-2 and eat-2 based on microarray studies. WB:WBGene00235092 C54F6.17 Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-2; let-60; and eat-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies. WB:WBGene00235093 C54F6.18 Enriched in pharynx and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by ten chemicals including stavudine; Sodium Chloride; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00235094 K08D9.9 Enriched in anterior spermatheca and posterior spermatheca based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on RNA-seq and microarray studies. Is affected by nine chemicals including bisphenol S; metformin; and Psoralens based on RNA-seq studies. WB:WBGene00235095 B0035.21 Enriched in ABplaapappp; ABpraapappp; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; hsf-1; and egl-43 based on RNA-seq studies. Is affected by metformin; Sirolimus; and paraquat based on RNA-seq studies. WB:WBGene00235096 thrm-2 No description available WB:WBGene00235097 thrm-3 No description available WB:WBGene00235098 thrm-4 No description available WB:WBGene00235099 thrm-5 No description available WB:WBGene00235100 disp-1 No description available WB:WBGene00235101 thrm-1 No description available WB:WBGene00235102 dib-1 Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex; U5 snRNP; and spliceosomal complex. Human ortholog(s) of this gene implicated in Burn-McKeown syndrome. Is an ortholog of human TXNL4A (thioredoxin like 4A). WB:WBGene00235106 F08H9.15 Is affected by several genes including daf-2; dpy-10; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including antimycin; Doxycycline; and paraquat based on RNA-seq and microarray studies. WB:WBGene00235107 Y41E3.465 No description available WB:WBGene00235108 Y69H2.28 Is affected by resveratrol based on microarray studies. WB:WBGene00235109 Y57G11A.226 Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; adr-1; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00235110 T14G12.12 Is affected by several genes including rrf-3; sir-2.1; and pmk-1 based on RNA-seq and microarray studies. Is affected by glycine and multi-walled carbon nanotube based on RNA-seq studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00235111 C25G4.16 No description available WB:WBGene00235112 T23B5.6 Is affected by nath-10 and bcf-1 based on RNA-seq studies. WB:WBGene00235113 ZK105.12 Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on RNA-seq and microarray studies. WB:WBGene00235114 ZK105.13 Enriched in amphid sheath cell; arcade cell; excretory gland cell; and pharyngeal-intestinal valve cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on RNA-seq and microarray studies. Is affected by six chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00235115 F47C12.13 Enriched in ABaraappaa and male-specific anatomical entity based on single-cell RNA-seq and microarray studies. Is affected by dlc-1 and eat-2 based on RNA-seq and microarray studies. Is affected by Diazinon based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF870, Caenorhabditis species and Caenorhabditis elegans protein of unknown function (DUF870). WB:WBGene00235116 C03G6.21 Predicted to be located in membrane. WB:WBGene00235117 Y19D10B.8 Is affected by eat-2; camt-1; and lpd-3 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain. WB:WBGene00235118 spp-26 Enriched in neurons based on RNA-seq studies. Is affected by daf-2 based on microarray studies. Is affected by adsorbable organic bromine compound and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. WB:WBGene00235119 R105.4 Is affected by daf-2; unc-30; and let-418 based on microarray and RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00235120 R105.5 Predicted to be located in extracellular space. WB:WBGene00235121 LLC1.121 Is affected by several genes including eat-2; sma-2; and sma-4 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00235122 mnm-6 No description available WB:WBGene00235123 mnm-7 No description available WB:WBGene00235124 mnm-8 No description available WB:WBGene00235128 F09E8.12 Is affected by daf-2 and mrps-5 based on microarray studies. WB:WBGene00235129 ZC518.8 Enriched in G2; W cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including egl-43; adr-1; and adr-2 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00235132 ZK792.12 Predicted to be located in membrane. WB:WBGene00235133 T26H5.14 Enriched in excretory duct; excretory pore; head mesodermal cell; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies. WB:WBGene00235134 R07H5.16 Enriched in GABAergic neurons based on RNA-seq studies. Is affected by lag-1 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00235138 C05C12.9 No description available WB:WBGene00235139 C06H5.10 No description available WB:WBGene00235143 R07H5.15 No description available WB:WBGene00235146 Y48G10A.10 No description available WB:WBGene00235147 Y60A3A.36 No description available WB:WBGene00235148 Y60A3A.30 No description available WB:WBGene00235150 Y71A12B.32 No description available WB:WBGene00235151 Y116F11B.27 No description available WB:WBGene00235152 Y7A5A.22 Is affected by dpy-21 and etr-1 based on RNA-seq studies. Is affected by paraquat and resveratrol based on RNA-seq and microarray studies. WB:WBGene00235153 Y7A5A.23 Is affected by unc-39 based on RNA-seq studies. WB:WBGene00235157 T03D8.8 Is affected by adr-2; rpl-33; and rpl-5 based on RNA-seq studies. WB:WBGene00235158 Y37E3.30 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; ciliated neurons; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by four chemicals including Rifampin; Psoralens; and stearic acid based on RNA-seq studies. WB:WBGene00235159 CD4.17 Enriched in AFD based on RNA-seq studies. Is affected by meg-3 based on RNA-seq studies. WB:WBGene00235160 CD4.18 Is affected by skn-1; sftb-1; and car-1 based on RNA-seq studies. WB:WBGene00235161 CD4.19 Is affected by sftb-1 and car-1 based on RNA-seq studies. WB:WBGene00235162 B0361.13 Is affected by daf-2; mett-10; and mrps-5 based on microarray and RNA-seq studies. WB:WBGene00235163 Y108G3AL.10 Enriched in AFD and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including sek-1; dpy-21; and sin-3 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00235164 K09F6.13 Enriched in neurons; rectal epithelial cell; and rectum based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-12; rrf-3; and eat-2 based on RNA-seq studies. Is affected by eight chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00235165 Y47D7A.18 Is affected by several genes including daf-2; rrf-3; and eat-2 based on RNA-seq and microarray studies. Is affected by allantoin based on microarray studies. WB:WBGene00235166 K08F4.15 No description available WB:WBGene00235167 F19B6.9 Is affected by npr-8 based on RNA-seq studies. WB:WBGene00235175 F20D1.21 Is affected by nfki-1 based on RNA-seq studies. WB:WBGene00235179 F32D1.12 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00235180 F35B3.10 Enriched in germ line based on RNA-seq studies. WB:WBGene00235181 F35E12.13 Is affected by adr-1 and lpd-3 based on RNA-seq studies. WB:WBGene00235183 F36A4.23 No description available WB:WBGene00235188 K09C6.12 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00235190 K10F12.10 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00235197 rrn-4.16 No description available WB:WBGene00235198 T09H2.2 No description available WB:WBGene00235200 T27A8.9 Is affected by daf-2 based on microarray studies. WB:WBGene00235201 T27C5.19 No description available WB:WBGene00235206 W07G1.24 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00235209 Y17G9A.90 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00235235 Y59E1B.14 Is affected by adr-1 and lag-1 based on RNA-seq studies. WB:WBGene00235237 Y71A12B.33 No description available WB:WBGene00235247 Y9C9A.111 Is affected by mett-10 based on RNA-seq studies. WB:WBGene00235250 C28G1.t5 No description available WB:WBGene00235251 K02D3.t1 No description available WB:WBGene00235252 Y73B6BL.t2 Is affected by daf-2 based on microarray studies. WB:WBGene00235254 F49D11.14 Predicted to be located in membrane. WB:WBGene00235255 K10H10.15 Is affected by daf-2 based on microarray studies. WB:WBGene00235256 Y54G11A.19 Predicted to be located in membrane. WB:WBGene00235257 T05C7.4 Predicted to be located in membrane. WB:WBGene00235258 T05C7.5 Is affected by elli-1 based on microarray studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00235259 T05C7.6 Is affected by elli-1; daf-12; and wdr-5.1 based on microarray and RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies. WB:WBGene00235260 T05C7.7 Is affected by adr-1 and eat-2 based on RNA-seq studies. WB:WBGene00235261 T05C7.8 Predicted to enable hydrolase activity. WB:WBGene00235262 T05C7.9 Enriched in neurons based on RNA-seq studies. Is affected by egl-43 based on RNA-seq studies. WB:WBGene00235263 Y66H1A.8 Enriched in AFD; GABAergic neurons; neurons; pm8; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and smg-1 based on RNA-seq and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00235264 M04G7.5 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by eat-2 and etr-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00235265 W03G1.11 Enriched in neurons based on RNA-seq studies. Is affected by eat-2 and pptr-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00235266 Y77E11A.22 Is affected by several genes including eat-2; dpy-21; and adr-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00235267 Y77E11A.23 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and Caappd based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and dcr-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00235268 Y54G2A.76 Enriched in hypodermis; seam cell; and tail hypodermis based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies. WB:WBGene00235269 F59E12.15 Predicted to enable histone H3T3 kinase activity. Predicted to be involved in intracellular signal transduction and mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. WB:WBGene00235270 F59E12.16 Enriched in intestine; muscle cell; neurons; and retrovesicular ganglion based on microarray studies. Is affected by several genes including daf-2; sir-2.1; and alg-1 based on RNA-seq and microarray studies. Is affected by Humic Substances; allantoin; and nitroguanidine based on microarray studies. WB:WBGene00235271 C49C8.8 Enriched in head mesodermal cell; intestine; neuronal sheath cell; neurons; and retrovesicular ganglion based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on RNA-seq and microarray studies. Is affected by nine chemicals including Sodium Chloride; metformin; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00235272 Y43B11AL.5 Is affected by several genes including daf-2; eat-2; and tdc-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00235273 T11F8.12 Predicted to be located in membrane. WB:WBGene00235274 C54E4.12 Predicted to be located in membrane. WB:WBGene00235275 T09A12.8 Enriched in MSaapaapa; MSpapaapa; g2L; and g2R based on single-cell RNA-seq studies. Is affected by fzo-1 and csr-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00235276 D2096.16 Enriched in germ line and head mesodermal cell based on RNA-seq studies. Is affected by several genes including eat-2; nhr-49; and dpy-21 based on RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00235277 T04C4.3 Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. WB:WBGene00235278 ZK185.10 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. WB:WBGene00235279 Y67D8C.22 Predicted to be involved in sensory perception of sound. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness. Is an ortholog of human CLRN2 (clarin 2). WB:WBGene00235280 F42A9.17 Enriched in intestine based on microarray studies. Is affected by several genes including eat-2; sir-2.1; and hsp-6 based on RNA-seq and microarray studies. Is affected by five chemicals including Ag nanoparticles; Doxycycline; and Tamoxifen based on RNA-seq and microarray studies. WB:WBGene00235281 Y4C6A.68 Enriched in male-specific anatomical entity based on microarray studies. Is affected by several genes including daf-2; eat-2; and isp-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Sodium Chloride; Rifampin; and Psoralens based on RNA-seq studies. WB:WBGene00235282 F17E9.18 Is affected by several genes including daf-2; tph-1; and csr-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00235283 Y55F3BL.6 Predicted to be located in membrane. WB:WBGene00235284 T12G3.11 Is affected by several genes including sir-2.1; dpl-1; and efl-1 based on RNA-seq and microarray studies. WB:WBGene00235285 F56D6.18 Predicted to be located in membrane. WB:WBGene00235286 C01F6.16 Is affected by several genes including sek-1; xpf-1; and dlc-1 based on RNA-seq studies. WB:WBGene00235287 Y55F3C.17 Predicted to enable microtubule binding activity. Predicted to be involved in translational initiation. Predicted to be located in microtubule cytoskeleton and sperm flagellum. WB:WBGene00235288 Y69A2AR.46 Is affected by several genes including daf-2; rrf-3; and eat-2 based on microarray and RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00235289 Y73B6BL.289 Predicted to enable gamma-tubulin binding activity. Predicted to be involved in endosomal transport and lysosome localization. Predicted to be part of BLOC-1 complex; BORC complex; and gamma-tubulin complex. WB:WBGene00235290 Y59H11AR.10 Predicted to be located in membrane. WB:WBGene00235291 C01G5.25 Enriched in several structures, including ABalaappppa; ABalapaappa; ABalapappaa; ABalappppaa; and neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00235292 F28E10.16 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-2; unc-30; and mir-35 based on RNA-seq and microarray studies. Is affected by six chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. WB:WBGene00235293 F56D6.19 Predicted to be located in membrane. WB:WBGene00235294 Y69A2AR.47 Is affected by several genes including daf-2; skn-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by five chemicals including Doxycycline; paraquat; and Humic Substances based on RNA-seq and microarray studies. WB:WBGene00235295 C42D4.19 Is affected by several genes including eat-2; mdt-15; and atfs-1 based on RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00235296 C07G1.15 Predicted to be located in membrane. WB:WBGene00235297 F56D6.20 Predicted to be located in membrane. WB:WBGene00235298 F19B6.10 Is affected by several genes including elt-2; elt-7; and nhr-114 based on RNA-seq studies. WB:WBGene00235299 Y69A2AR.48 Is affected by dlc-1 based on RNA-seq studies. WB:WBGene00235300 T06A10.107 Predicted to be located in membrane. WB:WBGene00235301 B0513.90 Is affected by several genes including tph-1; csr-1; and adr-1 based on RNA-seq studies. Is affected by six chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00235302 C07C7.3 Is affected by dpy-21; adr-1; and nfki-1 based on RNA-seq studies. WB:WBGene00235303 T13A10.64 Enriched in several structures, including ABalpppappp; ABalppppppp; ABplapaaaap; ABpraaaappp; and RME based on single-cell RNA-seq and RNA-seq studies. Is affected by adr-1 based on RNA-seq studies. WB:WBGene00235304 Y116A8C.468 Is affected by damt-1 and alh-4 based on RNA-seq studies. Is affected by four chemicals including antimycin; Doxycycline; and Tamoxifen based on RNA-seq studies. WB:WBGene00235305 Y116A8C.469 Enriched in DA neuron based on single-cell RNA-seq studies. Is affected by several genes including daf-2; daf-12; and tph-1 based on microarray and RNA-seq studies. Is affected by Doxycycline; Tamoxifen; and paraquat based on RNA-seq studies. WB:WBGene00235307 B0507.17 Is affected by several genes including sir-2.1; sek-1; and tph-1 based on RNA-seq and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00235308 C37C3.17 Enriched in several structures, including IL2 neuron; PVT; arcade cell; excretory gland cell; and rect_D based on single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Zidovudine; Rifampin; and allantoin based on RNA-seq and microarray studies. WB:WBGene00235309 F21C10.17 Enriched in AFD; intestine; and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and sek-1 based on RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00235310 R02D1.2 Predicted to enable isomerase activity. Predicted to be involved in biosynthetic process. Predicted to be located in cytoplasm. Is an ortholog of human PBLD (phenazine biosynthesis like protein domain containing). WB:WBGene00235311 Y57E12B.11 Predicted to be located in membrane. WB:WBGene00235312 F28A12.10 Enriched in ASG; ASGL; ASGR; and seam cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; spc-1; and etr-1 based on RNA-seq and microarray studies. WB:WBGene00235313 C25E10.17 Enriched in ASER; ASJ; neurons; and pharynx based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by Doxycycline; Tamoxifen; and paraquat based on RNA-seq studies. WB:WBGene00235314 B0348.9 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; dpy-21; and unc-70 based on RNA-seq and microarray studies. WB:WBGene00235315 Y50D4A.10 Predicted to be located in membrane. WB:WBGene00235316 B0222.15 Predicted to be located in membrane. WB:WBGene00235317 K04A8.19 Enriched in PLM and sensory neurons based on RNA-seq studies. Is affected by adr-1 and daf-2 based on RNA-seq and microarray studies. WB:WBGene00235318 K11D5.2 Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and nhr-49 based on RNA-seq and microarray studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00235319 F44E7.17 Enriched in germ line based on RNA-seq studies. Is affected by iff-1; mys-1; and lin-52 based on RNA-seq studies. WB:WBGene00235320 R02F11.11 Predicted to be located in membrane. WB:WBGene00235321 Y73C8B.9 Enriched in PLM based on RNA-seq studies. Is affected by dpy-21 and egl-43 based on RNA-seq studies. WB:WBGene00235322 F32F2.4 Is affected by dpy-21 and csr-1 based on RNA-seq studies. WB:WBGene00235323 F15B9.15 No description available WB:WBGene00235324 F10G2.10 Is affected by lpd-3 and sir-2.1 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00235325 C08D8.7 Predicted to be located in membrane. WB:WBGene00235326 F22F7.11 Is affected by five chemicals including Rifampin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00235327 srlf-20 Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00235328 T06E4.21 Predicted to be located in membrane. WB:WBGene00235329 F37B4.15 Is affected by smn-1; ikb-1; and camt-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00235330 F21C10.18 Enriched in pharyngeal-intestinal valve based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by five chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00235331 K07C11.14 No description available WB:WBGene00235332 K04A8.20 Enriched in arc ant V; head mesodermal cell; hyp3; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; rrf-3; and nhr-49 based on RNA-seq studies. Is affected by six chemicals including D-glucopyranose; Alovudine; and metformin based on RNA-seq studies. WB:WBGene00235333 C24H12.18 Predicted to be located in membrane. WB:WBGene00235334 F31F7.9 Is affected by dpy-21 and nhr-49 based on RNA-seq studies. WB:WBGene00235335 R02D5.24 Enriched in neurons based on RNA-seq studies. Is affected by egl-43 based on RNA-seq studies. Is affected by metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00235336 C54F6.19 Is affected by daf-2 based on microarray studies. WB:WBGene00235337 btr-2 No description available WB:WBGene00235338 C24H12.19 Is affected by several genes including daf-2; eat-2; and xpf-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. WB:WBGene00235339 F14F8.15 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by pqn-59 based on proteomic studies. Is affected by Rifampin based on RNA-seq studies. WB:WBGene00235340 C45G7.13 Enriched in several structures, including ABaraappaa; ABplpapppa; cephalic sheath cell; excretory cell; and pharyngeal-intestinal valve cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and let-60 based on RNA-seq and microarray studies. Is affected by seven chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies. WB:WBGene00235341 Y69A2AR.49 Is affected by rrf-3 and camt-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00235342 Y69A2AR.50 Predicted to be located in ribosome. WB:WBGene00235343 Y69A2AR.51 Is affected by several genes including aak-2; aak-1; and adr-1 based on RNA-seq studies. WB:WBGene00235346 Y94H6A.16 Is affected by several genes including daf-2; sod-2; and hda-2 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00235348 Y94H6A.17 Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00235350 Y54G2A.77 Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in sensory perception of chemical stimulus. Predicted to be located in membrane. WB:WBGene00235351 C32B5.18 Enriched in several structures, including DB neuron; RME; anterior hypodermis; interfacial epithelial cell; and pharyngeal muscle cell based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and tdc-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies. WB:WBGene00235352 ZK250.13 Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; FTH domain; and F-box domain. WB:WBGene00235353 Y67D8C.23 Is affected by several genes including daf-2; skn-1; and glp-1 based on RNA-seq studies. Is affected by six chemicals including Alovudine; Psoralens; and allantoin based on RNA-seq studies. WB:WBGene00235354 ZK250.14 Is affected by several genes including daf-2; skn-1; and eat-2 based on RNA-seq and microarray studies. Is affected by six chemicals including silicon dioxide nanoparticle; Doxycycline; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00235355 ZK250.15 Is affected by several genes including daf-2; tph-1; and pptr-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies. WB:WBGene00235356 Y67D8A.10 Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and atfs-1 based on RNA-seq studies. Is affected by Zidovudine and paraquat based on RNA-seq studies. WB:WBGene00235357 Y37E11B.16 No description available WB:WBGene00235358 F56D6.21 Predicted to be located in membrane. WB:WBGene00235359 F56D6.22 Predicted to be located in membrane. WB:WBGene00235361 F56D6.23 Predicted to be located in membrane. WB:WBGene00235362 Y46C8AL.12 Is affected by daf-2 and daf-16 based on microarray studies. WB:WBGene00235363 F49F1.2 Predicted to be located in membrane. WB:WBGene00235364 F49F1.4 Predicted to be located in membrane. WB:WBGene00235365 F49F1.15 Predicted to be located in membrane. WB:WBGene00235366 F49F1.16 No description available WB:WBGene00235367 F49F1.17 Is affected by several genes including daf-2; eat-2; and hda-1 based on RNA-seq and microarray studies. Is affected by four chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq studies. WB:WBGene00235368 F49F1.18 Predicted to enable galactoside binding activity. Is an ortholog of several human genes including CLC (Charcot-Leyden crystal galectin); LGALS13 (galectin 13); and LGALSL (galectin like). WB:WBGene00235369 K08D10.18 Is affected by several genes including daf-2; eat-2; and hsp-6 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00235370 K08D10.15 Is affected by eat-2; pptr-1; and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00235371 F30B5.11 Enriched in ABalaaaala and ABalaapaaa based on single-cell RNA-seq studies. Is affected by eat-2 and cfp-1 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00235372 F15E6.12 Is affected by several genes including lag-1; meg-3; and meg-4 based on RNA-seq studies. WB:WBGene00235373 Y24D9A.14 Is affected by several genes including hsp-6; unc-30; and dlc-1 based on RNA-seq studies. WB:WBGene00235374 R11E3.19 Enriched in AINL; AINR; and DVA based on single-cell RNA-seq studies. Is affected by several genes including eat-2; aak-2; and csr-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00235375 Y17G9A.91 Is affected by several genes including daf-2; pmk-1; and nhr-49 based on RNA-seq and microarray studies. Is affected by dibromoacetic acid based on microarray studies. WB:WBGene00235376 Y9C9A.112 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00235377 CE7X_3.4 Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00235378 E03H12.27 Is affected by adr-1 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies. WB:WBGene00235379 T28H11.31 Enriched in neurons based on RNA-seq studies. WB:WBGene00235380 C24D10.49 Enriched in SMB and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including eat-2; kri-1; and adr-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00235381 Y74C9A.9 Enriched in AVK and germ line based on RNA-seq studies. Is affected by several genes including unc-30; atfs-1; and let-418 based on RNA-seq studies. Is affected by Sirolimus based on RNA-seq studies. WB:WBGene00235382 ZK354.18 No description available WB:WBGene00235383 ZK616.65 Predicted to enable protein tyrosine phosphatase activity. WB:WBGene00235385 Y48G1A.7 Is affected by several genes including unc-30; atfs-1; and sma-2 based on RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and Doxycycline based on RNA-seq studies. WB:WBGene00235386 H32C10.101 No description available WB:WBGene00235387 W04C9.8 Enriched in AVK; HSN; I1L; I1R; and RIC based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including rrf-3; pptr-1; and xpo-1 based on RNA-seq studies. Is affected by bortezomib based on RNA-seq studies. WB:WBGene00235388 W04C9.9 Is affected by eat-2; hda-1; and ubc-9 based on RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and stearic acid based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00235389 C46G7.111 Enriched in neurons based on RNA-seq studies. Is affected by several genes including iff-1; sams-3; and sams-4 based on RNA-seq studies. WB:WBGene00235390 F56A6.8 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00235391 F38A5.22 Predicted to be located in cell surface and extracellular region. WB:WBGene00236785 Y73B6A.16 Is affected by adr-1; fzo-1; and camt-1 based on RNA-seq studies. WB:WBGene00236786 C17H12.37 Enriched in PLM; g2L; g2R; and muscle cell based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; eri-1; and rrf-1 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00236787 T22D1.22 Is affected by rnp-6 and nfki-1 based on RNA-seq studies. WB:WBGene00236788 ZK381.63 No description available WB:WBGene00236789 Y18H1A.18 Enriched in AVKL; AVKR; RICL; RICR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including spc-1; adr-1; and mrps-5 based on RNA-seq studies. WB:WBGene00236797 Y71G12B.44 Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by dlc-1; mrps-5; and bcat-1 based on RNA-seq studies. WB:WBGene00236798 F48C1.15 Enriched in neurons based on RNA-seq studies. Is affected by dlc-1 and etr-1 based on RNA-seq studies. WB:WBGene00236799 F54E2.8 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00236800 linc-171 Is affected by dlc-1 based on RNA-seq studies. Is affected by atracurium based on RNA-seq studies. WB:WBGene00236806 D2024.18 Is affected by several genes including eat-2; csr-1; and dlc-1 based on RNA-seq studies. WB:WBGene00236807 C06E4.22 No description available WB:WBGene00236808 C54G6.8 Is affected by several genes including crh-1; fzo-1; and swsn-9 based on RNA-seq studies. Is affected by Tamoxifen and paraquat based on RNA-seq studies. WB:WBGene00236809 ZK993.5 Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. WB:WBGene00249808 Y48G8AL.20 Is affected by several genes including sod-2; sma-2; and sma-4 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00249812 F39E9.25 Enriched in intestine based on microarray studies. Is affected by lin-14 and lin-4 based on microarray studies. WB:WBGene00249813 F39E9.26 Is affected by camt-1 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00249814 K08A2.17 No description available WB:WBGene00249815 F20D12.12 Enriched in germ line based on RNA-seq studies. Is affected by several genes including prg-1; atfs-1; and nuo-6 based on RNA-seq studies. Is affected by four chemicals including Rifampin; Sirolimus; and allantoin based on RNA-seq studies. WB:WBGene00249816 F42G8.18 Is affected by several genes including dpy-10; sir-2.1; and aak-2 based on RNA-seq and microarray studies. Is affected by paraquat; adsorbable organic bromine compound; and nitrotriazolone based on microarray studies. WB:WBGene00249817 ceph-41 Enriched in neurons and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including lin-4; lin-14; and sir-2.1 based on RNA-seq and microarray studies. Is affected by five chemicals including paraquat; Atrazine; and Colistin based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in Joubert syndrome 15. Is an ortholog of human CEP41 (centrosomal protein 41). WB:WBGene00249825 F17E9.19 Is affected by resveratrol based on microarray studies. WB:WBGene00249826 F42A9.18 Enriched in BAG and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including isp-1; nuo-6; and spc-1 based on RNA-seq studies. WB:WBGene00255375 F08B4.8 Enriched in AVG; RIM; command interneuron; and sperm based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; dpy-10; and pie-1 based on RNA-seq and microarray studies. Is affected by twenty-one chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00255420 Y51F10.15 Predicted to be located in membrane. WB:WBGene00255426 C04G2.14 Enriched in germ line based on RNA-seq studies. Is affected by several genes including rrf-3; sma-4; and spc-1 based on RNA-seq studies. Is affected by bortezomib based on RNA-seq studies. WB:WBGene00255435 K08C7.10 Enriched in neurons based on RNA-seq studies. WB:WBGene00255441 T11G6.11 Enriched in AFD based on RNA-seq studies. Is affected by unc-30; camt-1; and jmjd-5 based on RNA-seq studies. Is affected by Doxycycline; Tamoxifen; and paraquat based on RNA-seq studies. WB:WBGene00255457 F23C8.14 Enriched in several structures, including ABalppappa; ABarappppa; ABplpapppa; AIZ; and intestine based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including skn-1; eat-2; and elt-2 based on RNA-seq studies. Is affected by four chemicals including Sirolimus; Rifampin; and allantoin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Phosphorylation site. WB:WBGene00255469 C25G4.17 Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; hda-1; and nhr-8 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00255522 Y57G11B.223 No description available WB:WBGene00255543 Y41E3.466 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00255545 M199.135 No description available WB:WBGene00255546 M199.136 Enriched in neurons based on RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; and PAN-3 domain. WB:WBGene00255549 Y71F9B.24 Enriched in AFD based on RNA-seq studies. WB:WBGene00255550 W03D8.14 Enriched in muscle cell based on microarray studies. WB:WBGene00255553 Y51H4A.941 Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. WB:WBGene00255560 mir-8186.1 No description available WB:WBGene00255561 mir-8186.2 No description available WB:WBGene00255562 mir-8191 Is affected by met-2 based on RNA-seq studies. WB:WBGene00255563 mir-2217.2 No description available WB:WBGene00255564 mir-8206 No description available WB:WBGene00255565 mir-8203 Is affected by pptr-1 based on RNA-seq studies. WB:WBGene00255566 mir-8200 No description available WB:WBGene00255567 mir-8212 No description available WB:WBGene00255568 mir-8204 No description available WB:WBGene00255569 mir-8195 No description available WB:WBGene00255570 mir-8207 No description available WB:WBGene00255571 mir-2217.4 No description available WB:WBGene00255572 mir-8189 Enriched in neurons based on RNA-seq studies. WB:WBGene00255573 mir-8197 Is affected by daf-12 based on RNA-seq studies. WB:WBGene00255574 mir-8208 No description available WB:WBGene00255575 mir-8188 No description available WB:WBGene00255576 mir-8190 No description available WB:WBGene00255577 mir-8205 No description available WB:WBGene00255578 mir-8193 Enriched in neurons based on RNA-seq studies. WB:WBGene00255579 mir-8194 No description available WB:WBGene00255580 mir-8211 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00255581 mir-4810.2 No description available WB:WBGene00255582 mir-8201 No description available WB:WBGene00255583 mir-2217.5 No description available WB:WBGene00255584 mir-8187 Enriched in AFD based on RNA-seq studies. WB:WBGene00255586 mir-8202 Enriched in neurons based on RNA-seq studies. WB:WBGene00255587 mir-2217.3 No description available WB:WBGene00255588 mir-8198 No description available WB:WBGene00255594 Y48G1BL.8 Predicted to enable DNA binding activity. Predicted to be located in nucleus. Is an ortholog of human SNAPC3 (small nuclear RNA activating complex polypeptide 3). WB:WBGene00255595 D1046.18 Predicted to be located in membrane. WB:WBGene00255596 Y37B11A.8 Enriched in AVK based on RNA-seq studies. Is affected by several genes including daf-2; isp-1; and atfs-1 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00255597 pals-21 Is affected by eat-2; ints-4; and etr-1 based on RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and bortezomib based on RNA-seq and microarray studies. WB:WBGene00255598 BE0003N10.6 Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in membrane. WB:WBGene00255600 F54H5.14 Predicted to enable lipid binding activity. WB:WBGene00255605 T23B3.8 Enriched in neurons based on RNA-seq and microarray studies. Is affected by several genes including eat-2; rde-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by fluoranthene based on microarray studies. WB:WBGene00255606 T23B3.9 Enriched in ASH based on single-cell RNA-seq studies. Is affected by spc-1; unc-70; and etr-1 based on RNA-seq studies. WB:WBGene00255607 F22H10.11 Enriched in BAGL; BAGR; and coelomocyte based on single-cell RNA-seq studies. WB:WBGene00255611 Y116A8C.470 No description available WB:WBGene00255702 C06A12.19 Predicted to be located in membrane. WB:WBGene00255703 C06A12.20 No description available WB:WBGene00255704 B0348.10 Enriched in AVK and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including egl-43; adr-1; and pqn-59 based on RNA-seq and proteomic studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies. WB:WBGene00255709 Y116A8C.471 Is affected by Tamoxifen and paraquat based on RNA-seq studies. WB:WBGene00255714 B0511.19 Predicted to be located in membrane. WB:WBGene00255715 sacy-2 No description available WB:WBGene00255716 sacy-3 No description available WB:WBGene00255717 sacy-4 No description available WB:WBGene00255728 R02C2.8 Is affected by several genes including isp-1; unc-30; and mrps-5 based on RNA-seq studies. Is affected by Doxycycline and paraquat based on RNA-seq studies. WB:WBGene00255729 R11G11.16 Is affected by silicon dioxide nanoparticle based on RNA-seq studies. WB:WBGene00255730 F48G7.15 Is affected by ints-2; camt-1; and etr-1 based on RNA-seq studies. WB:WBGene00255731 srlf-21 Is affected by nas-38 based on RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00255732 srlf-22 Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00255733 srlf-23 Enriched in intestinal muscle and rectal muscle based on single-cell RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain. WB:WBGene00255734 gin-1 No description available WB:WBGene00255735 gin-2 No description available WB:WBGene00255736 C03H5.10 Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by unc-30 and etr-1 based on RNA-seq studies. Is affected by Doxycycline based on RNA-seq studies. WB:WBGene00268189 Y50D4B.9 Is affected by several genes including mrps-5; his-3; and pals-25 based on RNA-seq studies. Is affected by four chemicals including Rifampin; Psoralens; and bortezomib based on RNA-seq and microarray studies. WB:WBGene00268190 Y50D4B.10 Is affected by pptr-1 and camt-1 based on RNA-seq studies. WB:WBGene00268191 Y50D4A.12 Is affected by fbf-1 based on microarray studies. Is affected by adsorbable organic bromine compound; Sirolimus; and allantoin based on microarray studies. WB:WBGene00268192 ZK697.17 Is affected by eat-2; hda-2; and qui-1 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. WB:WBGene00268193 ZK697.18 Is affected by qui-1 based on RNA-seq studies. WB:WBGene00268194 F36H9.10 Enriched in neurons based on RNA-seq studies. Is affected by csr-1 and qui-1 based on RNA-seq studies. Is predicted to encode a protein with the following domain: Snake toxin-like superfamily. WB:WBGene00268195 susm-1 No description available WB:WBGene00268196 F59A7.14 Predicted to be located in membrane. WB:WBGene00268197 Y40B10A.11 Is affected by rnp-6 and csr-1 based on RNA-seq studies. WB:WBGene00268198 F22F7.12 Predicted to be located in membrane. WB:WBGene00268199 C45H4.21 Is affected by several genes including skn-1; dpy-7; and prg-1 based on RNA-seq; proteomic; and microarray studies. WB:WBGene00268202 T27B7.9 Is affected by rrf-3; sin-3; and spr-1 based on RNA-seq studies. WB:WBGene00268203 C29G2.7 Enriched in I5 neuron; cholinergic neurons; muscle cell; and retrovesicular ganglion based on microarray studies. WB:WBGene00268204 F53E10.8 Is affected by several genes including dpy-10; lin-35; and rde-4 based on microarray studies. Is affected by five chemicals including Humic Substances; R24; and paraquat based on microarray studies. WB:WBGene00268205 C24B9.18 Is affected by resveratrol based on microarray studies. WB:WBGene00268206 F54E2.9 Predicted to be located in membrane. WB:WBGene00268207 W08F4.20 Is affected by several genes including mut-2; lin-54; and tdp-1 based on RNA-seq and microarray studies. WB:WBGene00268208 W08F4.21 Is affected by meg-3; meg-4; and pptr-1 based on RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00268209 T04B8.6 Is affected by unc-30; isp-1; and nuo-6 based on RNA-seq and microarray studies. Is affected by paraquat based on microarray studies. WB:WBGene00268210 K07E8.15 Is affected by etr-1 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00268211 T02H6.12 Is affected by several genes including mrps-5; olrn-1; and etr-1 based on RNA-seq studies. WB:WBGene00268212 D1065.6 Is affected by hda-2; etr-1; and lbp-3 based on RNA-seq studies. WB:WBGene00268213 C17B7.15 Is affected by several genes including rrf-3; sir-2.1; and unc-30 based on RNA-seq and microarray studies. Is affected by five chemicals including sucrose; resveratrol; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00268214 C49F5.12 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00268215 C49F5.13 Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and Caappd based on single-cell RNA-seq studies. Is affected by mrps-5 and daf-18 based on RNA-seq studies. WB:WBGene00268216 F49B2.9 Enriched in ABalpppappp; ABplaapappp; ABpraaaappp; ABpraapappp; and ciliated neurons based on single-cell RNA-seq studies. Is affected by sir-2.1; isp-1; and mrps-5 based on microarray studies. Is affected by Diazinon and Colistin based on microarray studies. WB:WBGene00269331 Y39F10A.5 Is affected by mut-2 and rrf-3 based on microarray studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00269332 Y39F10A.6 No description available WB:WBGene00269333 F46F5.19 Is affected by rrf-3; smn-1; and unc-30 based on RNA-seq studies. WB:WBGene00269336 F28A10.11 Is affected by mrps-5 and hsf-1 based on RNA-seq studies. Is affected by glycine and Tamoxifen based on RNA-seq studies. WB:WBGene00269337 F28A10.12 Enriched in sperm based on single-cell RNA-seq studies. Is affected by several genes including adr-1; mrps-5; and etr-1 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00269338 R07C3.16 Is affected by several genes including hpl-2; his-24; and hpl-1 based on RNA-seq and microarray studies. WB:WBGene00269346 R07C3.17 Is affected by cpl-1 based on RNA-seq studies. Is affected by Tamoxifen based on RNA-seq studies. WB:WBGene00269352 K08D9.10 No description available WB:WBGene00269355 T28A11.25 Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; sir-2.1; and aak-2 based on RNA-seq and microarray studies. Is affected by five chemicals including resveratrol; Cry5B; and Colistin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00269373 M01D1.12 Enriched in several structures, including ABalaaaala; ABalaapaaa; ABalaappppa; AUA; and ciliated neurons based on single-cell RNA-seq studies. Is affected by several genes including sin-3; hda-2; and spr-1 based on RNA-seq studies. Is affected by stearic acid and sucrose based on RNA-seq studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00269376 C04G6.15 Enriched in AFD based on RNA-seq studies. Is affected by several genes including hsf-1; lag-1; and met-2 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies. WB:WBGene00269378 C07G3.15 Is affected by several genes including csr-1; adr-1; and tdp-1 based on RNA-seq and microarray studies. Is affected by Atrazine and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00269379 C30B5.17 Predicted to be located in membrane. WB:WBGene00269380 sow-2 No description available WB:WBGene00269381 F08F8.11 Is affected by several genes including sir-2.1; nuo-6; and mrps-5 based on RNA-seq and microarray studies. Is affected by Diazinon; paraquat; and adsorbable organic bromine compound based on microarray studies. WB:WBGene00269382 F33D11.16 Enriched in nerve ring neurons; pharyngeal-intestinal valve; and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; hda-2; and etr-1 based on RNA-seq studies. WB:WBGene00269383 ZK384.7 Enriched in PVM; amphid neurons; and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including rrf-3; unc-30; and mut-16 based on RNA-seq studies. WB:WBGene00269384 K09H11.16 Is affected by several genes including pptr-1; xpo-1; and olrn-1 based on RNA-seq studies. WB:WBGene00269385 F41F3.9 Predicted to be located in membrane. WB:WBGene00269386 F41F3.10 Enriched in neurons based on RNA-seq studies. Is affected by etr-1 based on RNA-seq studies. WB:WBGene00269387 btb-22 Predicted to be located in membrane. WB:WBGene00269388 F45C12.17 Predicted to be located in membrane. WB:WBGene00269389 C08F1.12 Predicted to be located in membrane. WB:WBGene00269390 C08F1.13 Enriched in muscle cell based on microarray studies. Is affected by several genes including mut-2; lin-54; and hda-2 based on RNA-seq and microarray studies. WB:WBGene00269391 F54F2.14 Enriched in neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by sin-3; mrps-5; and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00269392 F54F7.14 Predicted to be located in membrane. WB:WBGene00269393 F56H1.11 Is affected by adr-1; etr-1; and mrps-5 based on RNA-seq and microarray studies. WB:WBGene00269394 F59H6.15 Predicted to be located in membrane. WB:WBGene00269419 K05F6.15 Is affected by several genes including eat-2; mir-35; and lin-54 based on RNA-seq and microarray studies. Is affected by five chemicals including resveratrol; Atrazine; and Quercetin based on microarray studies. WB:WBGene00269420 K05F6.16 Enriched in muscle cell based on microarray studies. Is affected by adr-1 based on RNA-seq studies. Is affected by copper sulfate and Sirolimus based on microarray studies. WB:WBGene00269421 R06F6.14 Enriched in g1P based on single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Colistin; Sirolimus; and triclosan based on microarray and RNA-seq studies. WB:WBGene00269422 T01H10.11 No description available WB:WBGene00269423 W08A12.5 No description available WB:WBGene00269424 K09D9.14 Predicted to be located in membrane. WB:WBGene00269425 C49G7.13 Is affected by several genes including lin-4; lin-14; and sir-2.1 based on RNA-seq and microarray studies. Is affected by sucrose and stearic acid based on RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain. WB:WBGene00269426 C49G7.14 No description available WB:WBGene00269427 D1065.7 Enriched in neurons based on RNA-seq studies. WB:WBGene00269428 D1065.8 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00269429 H43I07.4 Enriched in AWB and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including pie-1; fasn-1; and hda-2 based on RNA-seq studies. WB:WBGene00269430 F47D2.12 No description available WB:WBGene00269431 T16A1.10 Enriched in several structures, including ABalaaaala; ABalaaaarl; ABalaaaarr; ciliated neurons; and pharyngeal cell based on single-cell RNA-seq studies. Is affected by several genes including rrf-3; set-2; and ain-1 based on RNA-seq and microarray studies. WB:WBGene00269432 ZC132.11 Predicted to be located in membrane. WB:WBGene00269433 T16G12.12 Predicted to be located in membrane. WB:WBGene00269434 sqst-5 Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity and protein kinase C binding activity. Predicted to be involved in aggrephagy; endosome organization; and mitophagy. Predicted to be located in aggresome and amphisome. WB:WBGene00269435 T27C10.9 Predicted to enable calcium ion binding activity and enzyme regulator activity. WB:WBGene00269436 F13A2.14 Is affected by hda-2; etr-1; and xpo-1 based on RNA-seq studies. WB:WBGene00269437 Y47D7A.19 Is affected by rrf-3 based on RNA-seq studies. WB:WBGene00269438 Y56A3A.41 Predicted to enable nucleic acid binding activity. WB:WBGene00270290 ZK938.11 Predicted to be involved in protein transport. Predicted to be located in cytoplasm. WB:WBGene00270291 F36H5.15 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00270292 F36H5.16 Is affected by hda-2 and etr-1 based on RNA-seq studies. WB:WBGene00270293 F36H5.17 Enriched in ABplpppppp; ABprpppppp; MC neuron; and body wall muscle cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; let-418; and rrf-2 based on RNA-seq and microarray studies. Is affected by Chlorpyrifos; Diazinon; and dafa#1 based on microarray studies. WB:WBGene00270296 drop-2 No description available WB:WBGene00270297 drop-3 No description available WB:WBGene00270298 drop-5 No description available WB:WBGene00270299 drop-6 No description available WB:WBGene00270300 drop-7 No description available WB:WBGene00270302 drop-9 No description available WB:WBGene00270303 T28D9.16 Predicted to be located in membrane. WB:WBGene00270309 K05F1.13 Enriched in neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including csr-1; daf-19; and adr-1 based on RNA-seq and microarray studies. WB:WBGene00270310 nde-5 No description available WB:WBGene00270318 F26G1.15 Enriched in AIYL; AIYR; SDQ; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including skn-1; isp-1; and unc-30 based on RNA-seq studies. WB:WBGene00270319 F26A1.19 Predicted to be involved in neuropeptide signaling pathway. WB:WBGene00270320 F27D9.13 Predicted to enable metalloendopeptidase activity. Predicted to be involved in membrane protein ectodomain proteolysis. WB:WBGene00270321 Y41C4A.32 Predicted to be involved in Golgi vesicle transport and intracellular protein transport. Predicted to be part of COPI vesicle coat. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 19. Is an ortholog of human COPB2 (COPI coat complex subunit beta 2). WB:WBGene00270322 C17G10.13 Predicted to enable DNA binding activity. Predicted to be involved in negative regulation of vulval development. WB:WBGene00271414 T05A7.12 Enriched in XXXL and XXXR based on single-cell RNA-seq studies. Is affected by several genes including met-2; spr-5; and hda-2 based on RNA-seq studies. Is predicted to encode a protein with the following domain: Protein-tyrosine phosphatase-like. WB:WBGene00271415 T05A7.13 Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. WB:WBGene00271437 F10D2.16 Predicted to be located in membrane. WB:WBGene00271444 T04C12.33 Predicted to be located in membrane. WB:WBGene00271567 T28F4.8 Is affected by raga-1 and csr-1 based on RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00271577 B0244.16 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00271598 Y18D10A.30 Is affected by atracurium based on RNA-seq studies. WB:WBGene00271605 H05L14.3 Predicted to be located in microtubule organizing center. WB:WBGene00271606 F22F4.9 Enriched in several structures, including ABplppppaa; ABprppppaa; corpus; rectal epithelial cell; and rectum based on single-cell RNA-seq studies. Is affected by several genes including skn-1; rrf-3; and sin-3 based on RNA-seq studies. WB:WBGene00271632 Y110A7A.24 Enriched in neurons based on RNA-seq studies. Is affected by adr-1; etr-1; and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00271633 F27B3.9 Enriched in neurons based on RNA-seq studies. Is affected by several genes including lin-35; dpl-1; and efl-1 based on RNA-seq and microarray studies. WB:WBGene00271634 M18.12 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00271635 T01H3.11 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00271636 W05G11.8 Enriched in XXX cell and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including unc-30; lipl-4; and hda-2 based on RNA-seq studies. WB:WBGene00271637 B0280.21 No description available WB:WBGene00271638 B0280.22 Enriched in neurons based on RNA-seq studies. WB:WBGene00271639 C50F2.12 No description available WB:WBGene00271640 Y66H1A.9 Enriched in intestine based on microarray studies. Is affected by sir-2.1 based on microarray studies. WB:WBGene00271641 K04G7.14 No description available WB:WBGene00271642 R106.8 Enriched in DD neuron and neurons based on microarray studies. Is affected by several genes including dpy-10; eat-2; and lin-35 based on RNA-seq and microarray studies. Is affected by four chemicals including Quercetin; Hydrolyzable Tannins; and Sirolimus based on microarray studies. WB:WBGene00271643 W07G1.25 Is affected by several genes including ceh-60; etr-1; and lpd-3 based on RNA-seq studies. Is affected by glycine based on RNA-seq studies. WB:WBGene00271644 K09F6.14 Enriched in AFD based on RNA-seq studies. Is affected by mrps-5 based on RNA-seq studies. WB:WBGene00271645 ZK1236.12 Is affected by fhod-1 and sir-2.1 based on RNA-seq and microarray studies. Is affected by bortezomib based on RNA-seq studies. WB:WBGene00271646 C26B2.15 Enriched in neurons based on RNA-seq studies. Is affected by mrps-5 and etr-1 based on RNA-seq studies. WB:WBGene00271647 C23G10.14 Is affected by several genes including rrf-3; unc-30; and unc-120 based on RNA-seq studies. WB:WBGene00271648 H06O01.5 Is affected by etr-1 based on RNA-seq studies. Is affected by resveratrol based on microarray studies. WB:WBGene00271649 T22A3.13 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00271650 C17G10.14 Is affected by adr-1 and etr-1 based on RNA-seq studies. WB:WBGene00271651 F19B10.14 Is affected by several genes including met-2; spr-5; and lin-52 based on RNA-seq studies. Is affected by bortezomib and Tamoxifen based on RNA-seq studies. WB:WBGene00271652 C28G1.11 Is affected by etr-1 based on RNA-seq studies. WB:WBGene00271653 Y47G6A.39 No description available WB:WBGene00271654 Y54G9A.17 No description available WB:WBGene00271655 M110.13 Is affected by sir-2.1 based on microarray studies. WB:WBGene00271656 T05G5.17 Enriched in intestine based on microarray studies. Is affected by sir-2.1 based on microarray studies. WB:WBGene00271657 Y38E10A.33 Is affected by adr-1 and olrn-1 based on RNA-seq studies. WB:WBGene00271694 T10E9.14 Predicted to enable mRNA binding activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of polysome. Human ortholog(s) of this gene implicated in congenital myopathy 9A and congenital myopathy 9B. Is an ortholog of human FXR1 (FMR1 autosomal homolog 1). WB:WBGene00271701 F10D7.10 Enriched in AIZL and AIZR based on single-cell RNA-seq studies. Is affected by csr-1; hda-2; and etr-1 based on RNA-seq studies. WB:WBGene00271703 ZK1010.12 Is affected by several genes including hpl-2; his-24; and ubc-9 based on RNA-seq and microarray studies. Is affected by resveratrol and dibromoacetic acid based on microarray studies. WB:WBGene00271706 D2089.8 Is affected by several genes including skn-1; hsf-1; and fbf-1 based on RNA-seq and microarray studies. Is affected by four chemicals including antimycin; Hydrolyzable Tannins; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Cysteine-rich domain; Cysteine-rich DPF motif domain-containing protein 1; and Cysteine-rich domain, DPF-motif. Is an ortholog of human CDPF1 (cysteine rich DPF motif domain containing 1). WB:WBGene00271707 ZK105.14 Is predicted to encode a protein with the following domains: Domain of unknown function DUF19 and Domain of unknown function (DUF19). WB:WBGene00271715 B0244.17 Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00271716 F39E9.28 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00271744 K09F6.15 Enriched in AFD; DB neuron; and VB1 based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-2; eat-2; and unc-30 based on RNA-seq and microarray studies. Is affected by antimycin; bortezomib; and Sirolimus based on RNA-seq and microarray studies. WB:WBGene00271774 R02F2.10 Is affected by bcf-1 based on RNA-seq studies. WB:WBGene00271775 EGAP1.5 Enriched in head mesodermal cell; hermaphrodite distal tip cell; and male distal tip cell based on single-cell RNA-seq studies. Is affected by hda-1 and hda-2 based on RNA-seq studies. WB:WBGene00271776 F53G12.18 Predicted to be located in membrane. WB:WBGene00271777 Y48G8AR.8 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00271778 T01A4.9 Predicted to be located in membrane. WB:WBGene00271779 C35E7.12 Is affected by adr-1 based on RNA-seq studies. Is affected by Tamoxifen based on RNA-seq studies. WB:WBGene00271780 F11A6.16 Is affected by adr-1 based on RNA-seq studies. Is predicted to encode a protein with the following domain: Fungus-induced protein. WB:WBGene00271781 Y71F9AM.9 Enriched in M1 neuron based on single-cell RNA-seq studies. Is affected by adr-1 and hda-2 based on RNA-seq studies. Is affected by atracurium; bortezomib; and Tamoxifen based on RNA-seq studies. WB:WBGene00271786 F58H7.11 Is affected by several genes including qui-1; adr-1; and hda-2 based on RNA-seq and microarray studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00271788 M01H9.10 Predicted to be located in membrane. WB:WBGene00271789 K01G12.22 Is affected by adr-1; mut-2; and rrf-3 based on RNA-seq and microarray studies. WB:WBGene00271790 W03D2.14 Is affected by mrps-5 based on microarray studies. WB:WBGene00271791 W03D2.15 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00271792 Y45F10C.21 No description available WB:WBGene00271795 Y46C8AM.1 Is affected by several genes including daf-16; skn-1; and daf-18 based on RNA-seq and microarray studies. Is affected by nitroguanidine based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00271796 C54F6.20 Enriched in rect_D; rect_VL; and rect_VR based on single-cell RNA-seq studies. Is affected by several genes including dcr-1; isp-1; and unc-30 based on RNA-seq and microarray studies. Is affected by four chemicals including Diazinon; Quercetin; and Humic Substances based on microarray studies. WB:WBGene00271797 E02C12.19 Is predicted to encode a protein with the following domains: Uncharacterized oxidoreductase dhs-27 and Uncharacterised oxidoreductase Dhs-27. WB:WBGene00271798 F54D5.24 Is affected by several genes including isp-1; pal-1; and csr-1 based on RNA-seq and microarray studies. Is affected by atracurium and Diazinon based on RNA-seq and microarray studies. WB:WBGene00271799 F07B7.17 Is affected by osm-8 and daf-19 based on microarray studies. Is affected by allantoin and pyoverdin based on microarray studies. WB:WBGene00271800 K06C4.27 No description available WB:WBGene00271801 F07B7.18 No description available WB:WBGene00271802 F10G2.11 Is affected by adr-1; ngn-1; and hda-2 based on RNA-seq studies. WB:WBGene00271803 C09G5.14 Is affected by unc-30 and hda-2 based on RNA-seq studies. WB:WBGene00271804 F11D11.22 Is affected by lpd-3 based on RNA-seq studies. Is affected by Sirolimus based on microarray studies. Is predicted to encode a protein with the following domain: Transmembrane glycoprotein. WB:WBGene00271805 T01E8.10 No description available WB:WBGene00271806 ZK938.12 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00271807 F19F10.14 Is affected by adr-1 based on RNA-seq studies. WB:WBGene00271808 F21C10.19 Enriched in ASI based on single-cell RNA-seq studies. Is affected by hda-2 and sir-2.1 based on RNA-seq and microarray studies. Is affected by Quercetin based on microarray studies. Is predicted to encode a protein with the following domains: CX module and Domain of unknown function CX. WB:WBGene00271809 D1022.17 Is affected by met-2; spr-5; and unc-30 based on RNA-seq studies. WB:WBGene00271810 C27H5.12 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00271811 C18H9.13 No description available WB:WBGene00271813 K03D7.12 No description available WB:WBGene00271815 spp-27 Is affected by several genes including daf-16; skn-1; and let-60 based on RNA-seq and microarray studies. Is affected by sixteen chemicals including sucrose; stearic acid; and Ag nanoparticles based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Saposin-like and Saposin B type domain. WB:WBGene00271816 R02F11.12 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like. WB:WBGene00271817 F55C12.19 Predicted to be located in membrane. WB:WBGene00271818 K05F1.14 Predicted to be located in membrane. WB:WBGene00271819 F10C1.23 Enriched in sperm based on single-cell RNA-seq studies. Is affected by several genes including skn-1; hsf-1; and unc-30 based on RNA-seq studies. Is affected by Tamoxifen and resveratrol based on RNA-seq and microarray studies. WB:WBGene00271820 T18H9.11 Is affected by adr-1 and pals-22 based on RNA-seq studies. WB:WBGene00271821 T28C12.15 Is affected by adr-1 and daf-18 based on RNA-seq studies. Is affected by CGP37157 based on RNA-seq studies. WB:WBGene00271822 F11G11.15 Predicted to be located in membrane. WB:WBGene00271823 C33F10.26 Is affected by unc-30 based on RNA-seq studies. WB:WBGene00271824 R03H10.11 Is affected by several genes including daf-16; eri-1; and rrf-1 based on RNA-seq and microarray studies. Is affected by paraquat; dafa#1; and Sirolimus based on microarray studies. WB:WBGene00271825 nipi-6 No description available WB:WBGene00271826 nipi-7 No description available WB:WBGene00271827 T19H12.15 Is affected by damt-1; csr-1; and lipl-4 based on RNA-seq studies. Is affected by antimycin; rotenone; and Tamoxifen based on RNA-seq studies. Is predicted to encode a protein with the following domain: CC domain. WB:WBGene00271828 nipi-8 No description available WB:WBGene00271829 nipi-9 No description available WB:WBGene00271830 W09G10.9 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00271831 Y46D2A.6 Is affected by lpd-3 based on RNA-seq studies. WB:WBGene00271832 Y60C6A.3 Enriched in RIC based on single-cell RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and lin-35 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including stearic acid; sucrose; and Cry5B based on RNA-seq and microarray studies. WB:WBGene00271837 Y65D7A.1 No description available WB:WBGene00271851 lov-3 No description available WB:WBGene00284844 H38K22.9 Predicted to be located in membrane. WB:WBGene00284845 Y71F9AR.10 No description available WB:WBGene00284846 ZC262.13 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00284847 F54D8.10 Is affected by several genes including daf-16; unc-30; and nhr-8 based on RNA-seq studies. Is affected by atracurium; bortezomib; and Tamoxifen based on RNA-seq studies. WB:WBGene00284848 M02E1.4 Is affected by daf-18 and vit-5 based on RNA-seq studies. WB:WBGene00284849 C03A3.9 Predicted to be located in membrane. WB:WBGene00284850 Y46B2A.4 Predicted to be located in membrane. WB:WBGene00284851 F28A10.13 Predicted to be located in ribosome. WB:WBGene00284852 M04F3.7 Is affected by sacy-1 and unc-30 based on RNA-seq studies. Is affected by atracurium and bortezomib based on RNA-seq studies. WB:WBGene00284853 C32E8.13 No description available WB:WBGene00284854 Y95D11A.5 Predicted to be located in membrane. WB:WBGene00284855 C04C11.25 Predicted to be located in membrane. WB:WBGene00284856 C09G1.7 No description available WB:WBGene00284857 W08E3.5 No description available WB:WBGene00284858 F32H2.15 No description available WB:WBGene00284859 C30G12.10 Enriched in ASEL; AWC-ON; and BAG based on single-cell RNA-seq studies. Is affected by hda-2 based on RNA-seq studies. WB:WBGene00284861 C30G12.11 Enriched in BAG based on single-cell RNA-seq studies. Is affected by hda-2 and lpd-3 based on RNA-seq studies. WB:WBGene00284867 T22B7.22 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00302964 Y62E10A.23 Enriched in I5 neuron; cholinergic neurons; muscle cell; and retrovesicular ganglion based on microarray studies. Is affected by several genes including skn-1; sir-2.1; and dcr-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Quercetin; paraquat; and Sirolimus based on microarray studies. WB:WBGene00302968 Y62E10A.24 Predicted to enable nucleic acid binding activity and ribonuclease P activity. Predicted to be involved in tRNA processing. Predicted to be located in nucleus. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Is an ortholog of human POP7 (POP7 homolog, ribonuclease P/MRP subunit). WB:WBGene00302971 F59E12.17 Enriched in intestine and neurons based on microarray studies. Is affected by several genes including sir-2.1; fbf-1; and nuo-6 based on RNA-seq; proteomic; and microarray studies. Is affected by Hydrolyzable Tannins based on microarray studies. WB:WBGene00302974 Y65B4BM.3 Is affected by several genes including skn-1; unc-30; and hda-1 based on RNA-seq and microarray studies. Is affected by bortezomib; Colistin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DB and DB module. WB:WBGene00302976 F49E8.8 Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human PIGF (phosphatidylinositol glycan anchor biosynthesis class F). WB:WBGene00302978 C42C1.19 Predicted to enable glucose 6-phosphate:inorganic phosphate antiporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II; glycogen storage disease Ib; and glycogen storage disease Ic. Is an ortholog of human SLC37A4 (solute carrier family 37 member 4). WB:WBGene00302980 F53E2.2 Enables actin filament binding activity. Involved in several processes, including actin filament-based process; embryo development; and positive regulation of actin filament polymerization. Located in striated muscle thin filament. Part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in brain compression; gallbladder carcinoma; and nemaline myopathy 7. Is an ortholog of human CFL2 (cofilin 2). WB:WBGene00302982 W02H5.19 Is affected by unc-30; hda-2; and nhr-25 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Coiled-coil domain containing protein 32 and Coiled-coil domain containing 32. WB:WBGene00302984 Y51H7C.41 Predicted to be located in membrane. Is an ortholog of human SMIM7 (small integral membrane protein 7). WB:WBGene00302986 Y37E11AM.4 Is affected by unc-30 based on RNA-seq studies. Is affected by four chemicals including cadmium; Hydrolyzable Tannins; and paraquat based on microarray studies. WB:WBGene00302988 F26D11.20 Enriched in intestine based on microarray studies. WB:WBGene00302991 cox-16 Involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX16 (cytochrome c oxidase assembly factor COX16). WB:WBGene00302993 T14B4.19 Enriched in male-specific anatomical entity based on microarray studies. Is affected by several genes including lin-4; lin-14; and sir-2.1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Atrazine; cadmium; and Quercetin based on microarray and RNA-seq studies. WB:WBGene00302995 H06H21.37 Predicted to be located in membrane. WB:WBGene00302998 F53G2.12 Predicted to be involved in iron-sulfur cluster assembly. Predicted to be located in mitochondrion. Predicted to be part of L-cysteine desulfurase complex. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 19. Is an ortholog of human LYRM4 (LYR motif containing 4). WB:WBGene00303000 C37C3.18 Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. WB:WBGene00303002 Y48E1B.17 Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 55. Is an ortholog of human PIGP (phosphatidylinositol glycan anchor biosynthesis class P). WB:WBGene00303005 C34E10.12 Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 34. Is an ortholog of human NDUFAF8 (NADH:ubiquinone oxidoreductase complex assembly factor 8). WB:WBGene00303007 Y57G11C.1147 Predicted to be involved in cell motility and regulation of actin polymerization or depolymerization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of SCAR complex. Is an ortholog of human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex). WB:WBGene00303009 mrpl-42 Predicted to be located in mitochondrion and ribosome. Is an ortholog of human MRPL42 (mitochondrial ribosomal protein L42). WB:WBGene00303011 F17C11.26 Enriched in intestine based on microarray studies. Is affected by sir-2.1 based on microarray studies. Is affected by Cholestanol and nitroguanidine based on microarray studies. WB:WBGene00303013 T04H1.12 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00303015 F20C5.11 Predicted to be located in membrane. WB:WBGene00303019 Y70G10A.4 Predicted to be located in membrane. WB:WBGene00303021 mccc-2 Predicted to enable ATP binding activity and ligase activity. Predicted to contribute to methylcrotonoyl-CoA carboxylase activity. Predicted to be involved in leucine catabolic process. Located in cytoplasm. Human ortholog(s) of this gene implicated in 3-Methylcrotonyl-CoA carboxylase 2 deficiency and mitochondrial metabolism disease. Is an ortholog of human MCCC2 (methylcrotonyl-CoA carboxylase subunit 2). WB:WBGene00303023 K07F5.22 Located in sarcoplasmic reticulum. Is an ortholog of human TMEM167B (transmembrane protein 167B). WB:WBGene00303024 H40L08.7 Is affected by several genes including dcr-1; mir-35; and nuo-6 based on RNA-seq and microarray studies. Is affected by six chemicals including Heme; Quercetin; and Humic Substances based on microarray studies. WB:WBGene00303026 T20D3.14 Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial intermembrane space. Is an ortholog of human COA4 (cytochrome c oxidase assembly factor 4 homolog). WB:WBGene00303028 F45H11.11 Is affected by hsf-1 based on RNA-seq studies. WB:WBGene00303030 C25A1.20 Predicted to be part of proteasome complex. WB:WBGene00303031 B0035.22 No description available WB:WBGene00303032 B0041.12 No description available WB:WBGene00303033 B0361.14 Enriched in intestine based on microarray studies. Is affected by sir-2.1 based on microarray studies. WB:WBGene00303034 C02C6.14 No description available WB:WBGene00303035 C07G2.5 No description available WB:WBGene00303036 C08B6.18 No description available WB:WBGene00303037 C09E8.6 No description available WB:WBGene00303038 C09E10.3 No description available WB:WBGene00303039 C13F10.8 No description available WB:WBGene00303040 C13G3.12 Is affected by sir-2.1 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00303041 C14C10.10 No description available WB:WBGene00303042 C26H9A.4 No description available WB:WBGene00303043 C28D4.18 No description available WB:WBGene00303044 C34D10.5 No description available WB:WBGene00303045 C43H6.12 Is affected by sir-2.1 based on microarray studies. WB:WBGene00303046 C48A7.16 No description available WB:WBGene00303047 C49F8.14 No description available WB:WBGene00303048 F55C5.17 No description available WB:WBGene00303049 C55C3.73 No description available WB:WBGene00303050 C56G2.22 No description available WB:WBGene00303051 F01E11.20 No description available WB:WBGene00303052 F08B12.11 No description available WB:WBGene00303053 F08C6.18 No description available WB:WBGene00303054 F44E5.17 No description available WB:WBGene00303055 F13G3.15 No description available WB:WBGene00303056 F27D4.12 No description available WB:WBGene00303057 F33D11.17 No description available WB:WBGene00303058 F47G4.14 Enriched in intestine based on microarray studies. Is affected by several genes including pie-1; lin-4; and lin-14 based on RNA-seq and microarray studies. Is affected by Cholestanol based on microarray studies. WB:WBGene00303059 F48F5.8 No description available WB:WBGene00303060 F52G3.7 No description available WB:WBGene00303061 F52H3.11 No description available WB:WBGene00303062 F55A4.13 No description available WB:WBGene00303063 T06E8.8 No description available WB:WBGene00303064 F59A6.13 No description available WB:WBGene00303065 H03A11.13 No description available WB:WBGene00303066 H40L08.8 No description available WB:WBGene00303067 K01D12.20 No description available WB:WBGene00303068 K08F8.15 Is affected by hda-2 and nhr-8 based on RNA-seq studies. WB:WBGene00303069 K11D12.14 No description available WB:WBGene00303070 C53H9.4 Is affected by daf-16 based on RNA-seq studies. WB:WBGene00303071 M176.16 No description available WB:WBGene00303072 R10E9.4 No description available WB:WBGene00303073 R12B2.13 No description available WB:WBGene00303074 T03G6.7 Is affected by ain-1 and ain-2 based on microarray studies. WB:WBGene00303075 T04C10.11 Enriched in body wall musculature; intestine; and muscle cell based on microarray studies. Is affected by several genes including daf-2; skn-1; and gld-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Quercetin; single-walled carbon nanotube; and paraquat based on microarray studies. WB:WBGene00303076 T04H1.13 No description available WB:WBGene00303077 T05A8.11 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00303078 T06D10.8 No description available WB:WBGene00303079 T09F3.7 No description available WB:WBGene00303080 T14B4.20 Is affected by sir-2.1 based on microarray studies. WB:WBGene00303081 bus-8A Predicted to be located in membrane. WB:WBGene00303082 T24D1.7 No description available WB:WBGene00303083 T28F3.11 No description available WB:WBGene00303085 Y32F6B.9 No description available WB:WBGene00303086 Y37D8A.29 No description available WB:WBGene00303087 Y39G8B.13 No description available WB:WBGene00303088 Y44E3A.7 No description available WB:WBGene00303089 Y46G5A.47 No description available WB:WBGene00303090 Y47D9A.7 No description available WB:WBGene00303091 Y50D4C.12 No description available WB:WBGene00303092 Y54F10AM.15 No description available WB:WBGene00303093 Y55B1BL.2 No description available WB:WBGene00303094 Y71G12A.5 No description available WB:WBGene00303095 Y71H2AL.4 No description available WB:WBGene00303096 Y75B8A.63 No description available WB:WBGene00303097 Y92H12BL.6 No description available WB:WBGene00303098 ZK377.15 No description available WB:WBGene00303099 ZK617.26 No description available WB:WBGene00303100 ZK856.19 Is affected by sir-2.1 based on microarray studies. WB:WBGene00303101 F20B6.10 Is affected by sir-2.1 based on microarray studies. WB:WBGene00303102 T19D2.13 No description available WB:WBGene00303103 W02D3.13 No description available WB:WBGene00303104 ZC328.8 No description available WB:WBGene00303105 R07E5.19 Predicted to be involved in vacuolar proton-transporting V-type ATPase complex assembly. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in X-linked myopathy with excessive autophagy. Is an ortholog of human VMA21 (vacuolar ATPase assembly factor VMA21). WB:WBGene00303113 F09A5.15 No description available WB:WBGene00303114 Y73B6A.17 No description available WB:WBGene00303115 B0462.6 No description available WB:WBGene00303139 bus-20 No description available WB:WBGene00303140 srf-10 No description available WB:WBGene00303141 bus-22 No description available WB:WBGene00303142 bus-25 No description available WB:WBGene00303143 bus-28 No description available WB:WBGene00303201 Y40C7B.11 No description available WB:WBGene00303208 Y71H2AM.29 Predicted to be located in membrane. WB:WBGene00303231 C53A3.4 Is affected by several genes including mut-2; mir-35; and lin-54 based on RNA-seq and microarray studies. WB:WBGene00303233 D1014.13 Is affected by several genes including hsf-1; unc-30; and prg-1 based on RNA-seq and microarray studies. Is affected by Chlorpyrifos; Diazinon; and nitroguanidine based on microarray studies. WB:WBGene00303359 ZK177.12 No description available WB:WBGene00303360 ZK177.13 No description available WB:WBGene00303362 C27D6.15 No description available WB:WBGene00303363 R03H10.12 Is affected by several genes including lin-35; alg-1; and hda-2 based on RNA-seq and microarray studies. Is affected by bortezomib; Sirolimus; and allantoin based on RNA-seq and microarray studies. WB:WBGene00303364 Y14H12A.5 Predicted to be located in membrane. WB:WBGene00303365 M151.10 Is affected by nhr-8 based on RNA-seq studies. WB:WBGene00303366 Y49F6A.11 Is affected by several genes including mir-35; hda-2; and mir-243 based on RNA-seq and microarray studies. Is affected by dibromoacetic acid and Colistin based on microarray studies. WB:WBGene00303367 Y49F6A.12 No description available WB:WBGene00303368 Y49F6B.19 No description available WB:WBGene00303369 Y49F6B.20 Is affected by nhr-8 based on RNA-seq studies. WB:WBGene00303370 Y59A8A.8 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00303371 F59F4.6 No description available WB:WBGene00303378 Y61B8B.3 No description available WB:WBGene00303398 F46H5.11 Predicted to enable transferase activity. WB:WBGene00303421 F20D6.15 Predicted to be located in membrane. WB:WBGene00303423 F10D7.11 Is affected by several genes including unc-30; tbx-2; and tdp-1 based on RNA-seq and microarray studies. Is affected by Diazinon and Hydrolyzable Tannins based on microarray studies. WB:WBGene00303425 R02E12.12 Predicted to enable metal ion binding activity. WB:WBGene00304173 F07E5.13 Is affected by several genes including pmk-1; nuo-6; and lipl-4 based on RNA-seq and microarray studies. Is affected by paraquat based on microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2; F-box associated; and F-box domain. WB:WBGene00304175 C37E2.10 Predicted to be located in endomembrane system. Is an ortholog of human ADTRP (androgen dependent TFPI regulating protein). WB:WBGene00304181 F38B7.17 Is affected by hda-2 based on RNA-seq studies. WB:WBGene00304182 K02E11.15 No description available WB:WBGene00304183 C15H11.17 No description available WB:WBGene00304189 C52E12.11 No description available WB:WBGene00304194 M163.21 No description available WB:WBGene00304195 M163.22 Predicted to be located in membrane. WB:WBGene00304201 T07H8.11 Is affected by several genes including daf-16; skn-1; and xbp-1 based on RNA-seq and microarray studies. Is affected by CGP37157 and bortezomib based on RNA-seq studies. WB:WBGene00304202 F07C3.17 No description available WB:WBGene00304203 D1086.21 Is affected by sacy-1 and hda-2 based on RNA-seq studies. WB:WBGene00304215 F17A2.16 Is affected by daf-18 and sir-2.1 based on RNA-seq and microarray studies. Is affected by cadmium and Sirolimus based on microarray studies. WB:WBGene00304219 Y49E10.37 No description available WB:WBGene00304220 F53G2.13 Is affected by Chlorpyrifos and Sirolimus based on microarray studies. WB:WBGene00304237 F39B3.7 Predicted to be located in membrane. WB:WBGene00304238 C33E10.12 No description available WB:WBGene00304775 Y38E10A.34 Predicted to be located in membrane. WB:WBGene00304776 K09A9.12 No description available WB:WBGene00304782 C23F12.9 Is affected by tbx-2 based on microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00304783 C31E10.11 No description available WB:WBGene00304785 C36C9.11 No description available WB:WBGene00304786 C36C9.12 Is affected by eat-2 based on microarray studies. WB:WBGene00304787 C49F8.15 Is affected by several genes including pmk-1; aak-2; and nhr-25 based on microarray studies. Is affected by four chemicals including Selenium; Colistin; and Sirolimus based on microarray studies. WB:WBGene00304788 C52B9.19 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hematologic cancer (multiple); and thrombocytopenia. Is an ortholog of several human genes including ETS1 (ETS proto-oncogene 1, transcription factor); ETS2 (ETS proto-oncogene 2, transcription factor); and ETV6 (ETS variant transcription factor 6). WB:WBGene00304789 F08F1.21 Is affected by unc-30 based on RNA-seq studies. WB:WBGene00304790 ZC53.22 Predicted to be located in membrane. WB:WBGene00304791 Y62H9A.16 Is affected by several genes including sir-2.1; rrf-1; and fasn-1 based on RNA-seq and microarray studies. Is affected by Diazinon based on microarray studies. WB:WBGene00304792 Y71F9AL.25 Predicted to be located in membrane. WB:WBGene00304793 H03G16.7 Is affected by several genes including mir-35; crh-1; and lin-54 based on microarray studies. Is affected by resveratrol based on microarray studies. WB:WBGene00304794 H40L08.9 Is affected by sir-2.1 based on microarray studies. WB:WBGene00304797 F31B9.7 Is affected by several genes including nhr-25; ain-1; and mrps-5 based on microarray studies. WB:WBGene00304798 F31B9.8 No description available WB:WBGene00304806 F41G4.13 Is affected by several genes including eat-2; mdt-15; and mut-2 based on microarray studies. Is affected by dafa#1 based on microarray studies. WB:WBGene00304808 F47E1.20 Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human PRDM14 (PR/SET domain 14). WB:WBGene00304811 mek-5 Predicted to enable MAP kinase kinase activity. Predicted to be involved in MAPK cascade. Predicted to be located in membrane. WB:WBGene00304812 ZK380.6 Enriched in coelomocyte; germ line; and neurons based on single-cell RNA-seq studies. Is affected by unc-30 based on RNA-seq studies. WB:WBGene00304813 F07G6.11 Enriched in AIN; ASI; and I4 neuron based on single-cell RNA-seq studies. Is affected by unc-30 based on RNA-seq studies. WB:WBGene00304814 F07G6.12 No description available WB:WBGene00304815 Y40A1A.6 Enriched in coelomocyte; germ line; and neurons based on single-cell RNA-seq studies. Is affected by unc-30 based on RNA-seq studies. WB:WBGene00304816 R11G1.11 Is affected by tdp-1 and hlh-25 based on microarray studies. Is affected by five chemicals including resveratrol; Atrazine; and Humic Substances based on microarray studies. WB:WBGene00304817 R160.12 Predicted to enable methyltransferase activity. Predicted to be involved in methylation. WB:WBGene00304818 R160.14 Predicted to be located in membrane. WB:WBGene00304819 R160.13 Predicted to be located in membrane. WB:WBGene00304820 R193.6 No description available WB:WBGene00304822 T14G8.6 Is affected by daf-19; tbx-2; and eat-2 based on microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00304823 Y7A5A.24 Enriched in DA neuron; I5 neuron; SAB; VA neuron; and retrovesicular ganglion based on microarray studies. Is affected by eat-2 based on microarray studies. Is affected by Atrazine; cadmium; and fluoranthene based on microarray studies. WB:WBGene00304824 Y7A5A.25 Is affected by unc-30; mut-2; and daf-19 based on RNA-seq and microarray studies. Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00304825 Y41G9A.17 Is affected by adsorbable organic bromine compound based on microarray studies. WB:WBGene00304826 Y59E1A.4 Enriched in muscle cell based on microarray studies. Is affected by sir-2.1 based on microarray studies. Is affected by fluoranthene and Sirolimus based on microarray studies. WB:WBGene00304827 Y73B3A.32 No description available WB:WBGene00304828 Y108F1.6 Is affected by nitroguanidine based on microarray studies. WB:WBGene00304895 F52G3.8 Is affected by unc-30 based on RNA-seq studies. WB:WBGene00304901 C04F6.9 No description available WB:WBGene00304906 Y81B9A.5 No description available WB:WBGene00304907 C03B1.17 Is affected by cadmium and fluoranthene based on microarray studies. WB:WBGene00304908 F20D1.22 Is affected by unc-30 based on RNA-seq studies. WB:WBGene00304930 Y50E8A.22 No description available WB:WBGene00304981 D1081.19 Is affected by several genes including isp-1; unc-30; and nuo-6 based on RNA-seq and microarray studies. Is affected by six chemicals including Atrazine; cadmium; and fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: Peptidase S1, PA clan; Nematode trypsin-6-like family; Chymotrypsin family Peptidase-S1; and Peptidase S1, PA clan, chymotrypsin-like fold. WB:WBGene00304985 D1081.20 Is predicted to encode a protein with the following domains: Snake toxin and toxin-like protein; Snake toxin-like superfamily; and Snake toxin/toxin-like. Is an ortholog of human LY6D (lymphocyte antigen 6 family member D). WB:WBGene00304992 F35C12.7 Enriched in male-specific anatomical entity based on microarray studies. Is affected by several genes including let-60; sir-2.1; and unc-30 based on RNA-seq and microarray studies. Is affected by Humic Substances and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: Snake toxin-like superfamily and Phosphorylation site. WB:WBGene00304996 F55A12.18 Is affected by several genes including daf-2; mdt-15; and tdp-1 based on RNA-seq and microarray studies. WB:WBGene00305018 K07A1.21 Enriched in intestine based on microarray studies. Is affected by several genes including dpy-10; isp-1; and unc-30 based on RNA-seq and microarray studies. Is affected by eight chemicals including Tamoxifen; resveratrol; and Acrylamide based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Transthyretin-like superfamily. WB:WBGene00305047 M01G12.15 Predicted to be located in membrane. WB:WBGene00305048 M01G12.16 Predicted to enable G protein-coupled peptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. WB:WBGene00305049 Y53C10A.24 Is affected by bcf-1 based on RNA-seq studies. WB:WBGene00305050 Y92H12BL.7 Predicted to be involved in signal transduction. Is an ortholog of human ARHGAP39 (Rho GTPase activating protein 39). WB:WBGene00305065 F14D2.20 No description available WB:WBGene00305066 Y55B1BR.8 Predicted to be located in membrane. WB:WBGene00305067 F10C5.3 Is affected by bcf-1 and sir-2.1 based on RNA-seq and microarray studies. WB:WBGene00305069 Y80D4G.2 Predicted to be located in membrane. WB:WBGene00305086 B0252.11 Predicted to be located in membrane. WB:WBGene00305090 C07D10.7 No description available WB:WBGene00305091 C16C8.26 Is affected by nath-10 and crh-1 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00305092 C16C8.25 No description available WB:WBGene00305093 C16C8.27 Enriched in male-specific anatomical entity based on microarray studies. Is affected by sir-2.1 based on microarray studies. Is affected by Progesterone based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00305095 C31C9.9 Is affected by isp-1 and nuo-6 based on microarray studies. Is affected by Sirolimus based on microarray studies. WB:WBGene00305102 C46F9.5 Is affected by Tamoxifen based on RNA-seq studies. WB:WBGene00305103 C16C4.19 No description available WB:WBGene00305104 C46F9.6 Is predicted to encode a protein with the following domains: MATH/TRAF domain and MATH domain. WB:WBGene00305109 C54A12.9 No description available WB:WBGene00305110 F08D12.15 Is affected by Atrazine and fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: F-box associated domain, type 2 and F-box associated. WB:WBGene00305111 F22E5.22 Is affected by several genes including pmk-1; tax-6; and ogt-1 based on microarray studies. Is affected by four chemicals including Testosterone; Colistin; and dafa#1 based on microarray studies. WB:WBGene00305112 F22E5.23 Enriched in intestine based on microarray studies. Is affected by rrf-1 based on microarray studies. Is affected by five chemicals including Cry5B; Chlorpyrifos; and Diazinon based on microarray studies. WB:WBGene00305113 F36H5.18 Predicted to be located in membrane. WB:WBGene00305114 F43C11.16 Is affected by alg-1 and daf-19 based on microarray studies. Is affected by Acrylamide based on microarray studies. Is predicted to encode a protein with the following domains: TRA-1 regulated and TRA-1 regulated protein R03H10.4. WB:WBGene00305130 F49C5.16 Is predicted to encode a protein with the following domains: Domain of unknown function DUF281 and Domain of unknown function (DUF281). WB:WBGene00305131 F54H12.10 Predicted to be located in membrane. WB:WBGene00305132 T10D4.19 Is affected by mut-2 based on microarray studies. Is affected by cadmium and Colistin based on microarray studies. Is predicted to encode a protein with the following domains: Uncharacterised protein family UPF0376; Domain of unknown function DUF19; and Domain of unknown function (DUF19). WB:WBGene00305157 T24H7.9 Involved in sterol metabolic process. WB:WBGene00305158 Y16E11A.4 Is affected by nath-10 based on RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like. WB:WBGene00305159 Y38E10A.35 Is affected by sir-2.1 based on microarray studies. Is affected by Atrazine based on microarray studies. WB:WBGene00305173 H12C20.7 Is affected by Atrazine and nitroguanidine based on microarray studies. WB:WBGene00305233 3R5.3 No description available WB:WBGene00305234 AC3.17 No description available WB:WBGene00305235 AH10.11 No description available WB:WBGene00305236 B0019.5 No description available WB:WBGene00305237 B0019.6 No description available WB:WBGene00305238 B0303.18 No description available WB:WBGene00305239 B0399.4 No description available WB:WBGene00305240 B0412.9 No description available WB:WBGene00305241 B0412.10 No description available WB:WBGene00305242 B0412.11 No description available WB:WBGene00305243 B0457.20 No description available WB:WBGene00305244 B0511.20 No description available WB:WBGene00305245 B0513.91 No description available WB:WBGene00305246 BE0003N10.7 No description available WB:WBGene00305247 C01G10.20 No description available WB:WBGene00305248 C01G10.21 No description available WB:WBGene00305249 C01G5.26 No description available WB:WBGene00305250 C01G6.14 No description available WB:WBGene00305251 C02C6.15 No description available WB:WBGene00305252 C02C6.16 No description available WB:WBGene00305253 C04E7.8 No description available WB:WBGene00305254 C05D10.8 No description available WB:WBGene00305255 C06A5.13 No description available WB:WBGene00305256 C06G3.19 No description available WB:WBGene00305257 C07B5.10 No description available WB:WBGene00305258 C08B11.14 No description available WB:WBGene00305259 C09D4.10 No description available WB:WBGene00305260 C09D8.16 No description available WB:WBGene00305261 C09E8.7 No description available WB:WBGene00305262 C10C6.14 No description available WB:WBGene00305263 C11G6.7 No description available WB:WBGene00305264 C13B9.6 No description available WB:WBGene00305265 C14A6.18 No description available WB:WBGene00305266 C14A6.19 No description available WB:WBGene00305267 C14A6.20 No description available WB:WBGene00305268 C15F1.16 No description available WB:WBGene00305269 C15H9.14 No description available WB:WBGene00305270 C15H9.15 No description available WB:WBGene00305271 C16A11.11 No description available WB:WBGene00305272 C16B8.14 No description available WB:WBGene00305273 C16C8.28 No description available WB:WBGene00305274 C16C8.29 No description available WB:WBGene00305275 C17D12.19 No description available WB:WBGene00305276 C17D12.20 No description available WB:WBGene00305277 C18A11.14 No description available WB:WBGene00305278 C18D11.12 No description available WB:WBGene00305279 C18E3.11 No description available WB:WBGene00305280 C18F3.13 No description available WB:WBGene00305281 C24A1.9 No description available WB:WBGene00305282 C24A8.14 No description available WB:WBGene00305283 C24G6.14 No description available WB:WBGene00305284 C24H12.20 No description available WB:WBGene00305285 C25D7.19 No description available WB:WBGene00305286 C25D7.20 No description available WB:WBGene00305287 C26H9A.5 No description available WB:WBGene00305288 C27A12.14 No description available WB:WBGene00305289 C28A5.13 No description available WB:WBGene00305290 C28D4.19 No description available WB:WBGene00305291 C28D4.20 No description available WB:WBGene00305292 C28D4.21 No description available WB:WBGene00305293 C29F7.12 No description available WB:WBGene00305294 C30B5.18 No description available WB:WBGene00305295 C31G12.17 No description available WB:WBGene00305296 C33F10.27 No description available WB:WBGene00305297 C33F10.28 No description available WB:WBGene00305298 C33G8.18 No description available WB:WBGene00305299 C33H5.22 No description available WB:WBGene00305300 C34E10.13 No description available WB:WBGene00305301 C34E7.9 No description available WB:WBGene00305302 C34F11.19 No description available WB:WBGene00305303 C35D10.20 No description available WB:WBGene00305304 C35E7.13 No description available WB:WBGene00305305 C36A4.15 No description available WB:WBGene00305306 C36F7.27 No description available WB:WBGene00305307 C37F5.2 No description available WB:WBGene00305308 C39B5.18 No description available WB:WBGene00305309 C39B5.17 No description available WB:WBGene00305310 C40A11.11 No description available WB:WBGene00305311 C40A11.12 No description available WB:WBGene00305312 C40H1.14 No description available WB:WBGene00305313 C41H7.12 No description available WB:WBGene00305314 C43D7.20 No description available WB:WBGene00305315 C43E11.14 No description available WB:WBGene00305316 C44E4.11 No description available WB:WBGene00305317 C44E4.12 No description available WB:WBGene00305318 C46A5.16 No description available WB:WBGene00305319 C46C2.13 No description available WB:WBGene00305320 C47B2.10 No description available WB:WBGene00305321 C47B2.11 No description available WB:WBGene00305322 C47B2.12 No description available WB:WBGene00305323 C48G7.5 No description available WB:WBGene00305324 C52E12.12 No description available WB:WBGene00305325 C52E4.19 No description available WB:WBGene00305326 C54C6.12 No description available WB:WBGene00305327 C54C6.13 No description available WB:WBGene00305328 C54C6.14 No description available WB:WBGene00305329 C55B7.14 No description available WB:WBGene00305330 C55B7.15 No description available WB:WBGene00305331 C56G2.23 No description available WB:WBGene00305332 CC4.4 No description available WB:WBGene00305333 CD4.20 No description available WB:WBGene00305334 D2013.14 No description available WB:WBGene00305335 DY3.13 No description available WB:WBGene00305336 E01A2.12 No description available WB:WBGene00305337 E03A3.12 No description available WB:WBGene00305338 F02A9.11 No description available WB:WBGene00305339 F02A9.12 No description available WB:WBGene00305340 F02A9.13 No description available WB:WBGene00305341 F02H6.73 No description available WB:WBGene00305342 F07A5.9 No description available WB:WBGene00305343 F07C6.9 No description available WB:WBGene00305344 F09E5.24 No description available WB:WBGene00305345 F09G2.15 No description available WB:WBGene00305346 F10D2.17 No description available WB:WBGene00305347 F10F2.17 No description available WB:WBGene00305348 F10F2.18 No description available WB:WBGene00305349 F11A10.10 No description available WB:WBGene00305350 F12A10.14 No description available WB:WBGene00305351 F13A7.16 No description available WB:WBGene00305352 F13A7.17 No description available WB:WBGene00305353 F13B9.11 No description available WB:WBGene00305354 F14E5.9 No description available WB:WBGene00305355 F15B10.5 No description available WB:WBGene00305356 F15B10.6 No description available WB:WBGene00305357 F15B9.16 No description available WB:WBGene00305358 F15D3.12 No description available WB:WBGene00305359 F18A12.10 No description available WB:WBGene00305360 F18A12.11 No description available WB:WBGene00305361 F19C7.9 No description available WB:WBGene00305362 F20H11.7 No description available WB:WBGene00305363 F21H12.11 No description available WB:WBGene00305364 F22B8.10 No description available WB:WBGene00305365 F22D6.19 No description available WB:WBGene00305366 F22G12.10 No description available WB:WBGene00305367 F25B5.12 No description available WB:WBGene00305368 F25H5.12 No description available WB:WBGene00305369 F25H8.26 No description available WB:WBGene00305370 F26D2.19 No description available WB:WBGene00305371 F26E4.19 No description available WB:WBGene00305372 F26E4.20 No description available WB:WBGene00305373 F26F12.21 No description available WB:WBGene00305374 F27C1.19 No description available WB:WBGene00305375 F27D4.13 No description available WB:WBGene00305376 F28B3.11 No description available WB:WBGene00305377 F28B3.12 No description available WB:WBGene00305378 F28F5.18 No description available WB:WBGene00305379 F31E3.14 No description available WB:WBGene00305380 F32F2.5 No description available WB:WBGene00305381 F32H2.16 No description available WB:WBGene00305382 F32H2.17 No description available WB:WBGene00305383 F33C8.11 No description available WB:WBGene00305384 F33E11.8 No description available WB:WBGene00305385 F33E11.9 No description available WB:WBGene00305386 F34D10.11 No description available WB:WBGene00305387 F35C5.14 No description available WB:WBGene00305388 F35E2.13 No description available WB:WBGene00305389 F35F11.5 No description available WB:WBGene00305390 F35F11.6 No description available WB:WBGene00305391 F35F11.7 No description available WB:WBGene00305392 F35G12.15 No description available WB:WBGene00305393 F36D3.17 No description available WB:WBGene00305394 F36D3.18 No description available WB:WBGene00305395 F36F2.12 No description available WB:WBGene00305396 F36G9.19 No description available WB:WBGene00305397 F36H5.19 No description available WB:WBGene00305398 F36H5.20 No description available WB:WBGene00305399 F37C4.9 No description available WB:WBGene00305400 F37D6.13 No description available WB:WBGene00305401 F37E3.6 No description available WB:WBGene00305402 F37H8.14 No description available WB:WBGene00305403 F38B7.18 No description available WB:WBGene00305404 F39B2.15 No description available WB:WBGene00305405 F39E9.29 No description available WB:WBGene00305406 F39H2.6 No description available WB:WBGene00305407 F40E10.15 No description available WB:WBGene00305408 F40E3.11 No description available WB:WBGene00305409 F40F12.12 No description available WB:WBGene00305410 F40F12.13 No description available WB:WBGene00305411 F40F12.14 No description available WB:WBGene00305412 F40F8.15 No description available WB:WBGene00305413 F40G9.23 No description available WB:WBGene00305414 F44B9.12 No description available WB:WBGene00305415 F44G4.9 No description available WB:WBGene00305416 F46A9.14 No description available WB:WBGene00305417 F46A9.15 No description available WB:WBGene00305418 F46B6.19 No description available WB:WBGene00305419 F46C5.15 No description available WB:WBGene00305420 F46H5.12 No description available WB:WBGene00305421 F47F6.16 No description available WB:WBGene00305422 F48F5.9 No description available WB:WBGene00305423 F49E8.9 No description available WB:WBGene00305424 F49H12.13 No description available WB:WBGene00305425 F52C12.7 No description available WB:WBGene00305426 F52E1.18 No description available WB:WBGene00305427 F52E1.19 No description available WB:WBGene00305428 F52G2.10 No description available WB:WBGene00305429 F52G2.11 No description available WB:WBGene00305430 F53A3.9 No description available WB:WBGene00305431 F53A3.10 No description available WB:WBGene00305432 F53A3.11 No description available WB:WBGene00305433 F53A3.12 No description available WB:WBGene00305434 F53A3.13 No description available WB:WBGene00305435 F53A3.14 No description available WB:WBGene00305436 F53F10.9 No description available WB:WBGene00305437 F53G12.19 No description available WB:WBGene00305438 F53H2.5 No description available WB:WBGene00305439 F53H2.6 No description available WB:WBGene00305440 F53H2.7 No description available WB:WBGene00305441 F54A3.12 No description available WB:WBGene00305442 F54A3.13 No description available WB:WBGene00305443 F54A3.14 No description available WB:WBGene00305444 F54A5.6 No description available WB:WBGene00305445 F54A5.7 No description available WB:WBGene00305446 F54C4.8 No description available WB:WBGene00305447 F54C4.9 No description available WB:WBGene00305448 F54D12.22 No description available WB:WBGene00305449 F54D12.23 No description available WB:WBGene00305450 F54F2.15 No description available WB:WBGene00305451 F54H12.11 No description available WB:WBGene00305452 F55A8.7 No description available WB:WBGene00305453 F55C9.16 No description available WB:WBGene00305454 F56A3.6 No description available WB:WBGene00305455 F56B3.16 No description available WB:WBGene00305456 F56D12.12 No description available WB:WBGene00305457 F56G4.9 No description available WB:WBGene00305458 F56G4.10 No description available WB:WBGene00305459 F56G4.11 No description available WB:WBGene00305460 F57B9.13 No description available WB:WBGene00305461 F57C2.7 No description available WB:WBGene00305462 F57C7.15 No description available WB:WBGene00305463 F57H12.11 No description available WB:WBGene00305464 F58B6.10 No description available WB:WBGene00305465 F58E10.8 No description available WB:WBGene00305466 F58G1.14 No description available WB:WBGene00305467 F59A7.15 No description available WB:WBGene00305468 F59E12.18 No description available WB:WBGene00305469 F59H5.7 No description available WB:WBGene00305470 F59H5.8 No description available WB:WBGene00305471 F59H5.9 No description available WB:WBGene00305472 H04J21.6 No description available WB:WBGene00305473 H04J21.5 No description available WB:WBGene00305474 H05C05.5 No description available WB:WBGene00305475 H06H21.38 No description available WB:WBGene00305476 H06I04.15 No description available WB:WBGene00305477 H06I04.16 No description available WB:WBGene00305478 H10D18.7 No description available WB:WBGene00305479 H12I13.7 No description available WB:WBGene00305480 H14A12.10 No description available WB:WBGene00305481 H17B01.6 No description available WB:WBGene00305482 H22D07.2 No description available WB:WBGene00305483 H27M09.9 No description available WB:WBGene00305484 H28O16.4 No description available WB:WBGene00305485 H37A05.7 No description available WB:WBGene00305486 H37N21.2 No description available WB:WBGene00305487 H38K22.10 No description available WB:WBGene00305488 H43I07.5 No description available WB:WBGene00305489 K01A11.9 No description available WB:WBGene00305490 K01A2.16 No description available WB:WBGene00305491 K01A2.17 No description available WB:WBGene00305492 K01A2.18 No description available WB:WBGene00305493 K01A2.19 No description available WB:WBGene00305494 K01A6.23 No description available WB:WBGene00305495 K01G5.13 No description available WB:WBGene00305496 K02B2.39 No description available WB:WBGene00305497 K02D10.9 No description available WB:WBGene00305498 K02E7.15 No description available WB:WBGene00305499 K02F3.16 No description available WB:WBGene00305500 K02F6.12 No description available WB:WBGene00305501 K03H4.8 No description available WB:WBGene00305502 K03H4.9 No description available WB:WBGene00305503 K03H4.10 No description available WB:WBGene00305504 K03H4.11 No description available WB:WBGene00305505 K04D7.18 No description available WB:WBGene00305506 K04G2.16 No description available WB:WBGene00305507 K05C4.12 No description available WB:WBGene00305508 K06B4.18 No description available WB:WBGene00305509 K07C11.15 No description available WB:WBGene00305510 K07E12.9 No description available WB:WBGene00305511 K07E12.10 No description available WB:WBGene00305512 K07E12.11 No description available WB:WBGene00305513 K07E8.16 No description available WB:WBGene00305514 K07F5.23 No description available WB:WBGene00305515 K08B4.44 No description available WB:WBGene00305516 K08D10.19 No description available WB:WBGene00305517 K08D10.20 No description available WB:WBGene00305518 K08D10.21 No description available WB:WBGene00305519 K08D10.22 No description available WB:WBGene00305520 K08H10.17 No description available WB:WBGene00305521 K09C6.13 No description available WB:WBGene00305522 K09E4.7 No description available WB:WBGene00305523 K09E4.8 No description available WB:WBGene00305524 K09H9.12 No description available WB:WBGene00305525 K10B3.12 No description available WB:WBGene00305526 K10B3.13 No description available WB:WBGene00305527 K10F12.11 No description available WB:WBGene00305528 K11H12.15 No description available WB:WBGene00305529 K12C11.9 No description available WB:WBGene00305530 M01E11.10 No description available WB:WBGene00305531 M01F1.12 No description available WB:WBGene00305532 M01G5.11 No description available WB:WBGene00305533 M01G5.12 No description available WB:WBGene00305534 M02D8.12 No description available WB:WBGene00305535 M03A1.13 No description available WB:WBGene00305536 M03F8.12 No description available WB:WBGene00305537 M04C9.10 No description available WB:WBGene00305538 M04D5.7 No description available WB:WBGene00305539 M04D5.8 No description available WB:WBGene00305540 M151.11 No description available WB:WBGene00305541 M151.12 No description available WB:WBGene00305542 M57.4 No description available WB:WBGene00305543 M70.14 No description available WB:WBGene00305544 M70.15 No description available WB:WBGene00305545 PAR2.6 No description available WB:WBGene00305546 R02C2.9 No description available WB:WBGene00305547 R02C2.10 No description available WB:WBGene00305548 R05H10.8 No description available WB:WBGene00305549 R06B10.9 No description available WB:WBGene00305550 R06B10.10 No description available WB:WBGene00305551 R06B10.11 No description available WB:WBGene00305552 R06B9.7 No description available WB:WBGene00305553 R06C1.15 No description available WB:WBGene00305554 R07C12.5 No description available WB:WBGene00305555 R07C3.18 No description available WB:WBGene00305556 R07C3.19 No description available WB:WBGene00305557 R07E5.20 No description available WB:WBGene00305558 R08A2.10 No description available WB:WBGene00305559 R107.12 No description available WB:WBGene00305560 R10E4.13 No description available WB:WBGene00305561 R10E9.5 No description available WB:WBGene00305562 R119.8 No description available WB:WBGene00305563 R119.9 No description available WB:WBGene00305564 R11E3.20 No description available WB:WBGene00305565 R12B2.14 No description available WB:WBGene00305566 R12E2.19 No description available WB:WBGene00305567 R13A5.18 No description available WB:WBGene00305568 R13H8.6 No description available WB:WBGene00305569 R155.9 No description available WB:WBGene00305570 R155.10 No description available WB:WBGene00305571 R52.13 No description available WB:WBGene00305572 T01A4.10 No description available WB:WBGene00305573 T01D1.9 No description available WB:WBGene00305574 T01D1.10 No description available WB:WBGene00305575 T02B11.14 No description available WB:WBGene00305576 T02G5.16 No description available WB:WBGene00305577 T02G5.17 No description available WB:WBGene00305578 T02H6.13 No description available WB:WBGene00305579 T02H6.14 No description available WB:WBGene00305580 T04C4.4 No description available WB:WBGene00305581 T04C4.5 No description available WB:WBGene00305582 T04D3.11 No description available WB:WBGene00305583 T05H4.17 No description available WB:WBGene00305584 T06A10.108 No description available WB:WBGene00305585 T06C12.18 No description available WB:WBGene00305586 T06E6.16 No description available WB:WBGene00305587 T07A5.9 No description available WB:WBGene00305588 T07A5.10 No description available WB:WBGene00305589 T07A9.18 No description available WB:WBGene00305590 T07C4.14 No description available WB:WBGene00305591 T07G12.20 No description available WB:WBGene00305592 T07G12.21 No description available WB:WBGene00305593 T08A11.3 No description available WB:WBGene00305594 T08B2.16 No description available WB:WBGene00305595 T08B2.17 No description available WB:WBGene00305596 T09B4.24 No description available WB:WBGene00305597 T10B11.11 No description available WB:WBGene00305598 T10D4.20 No description available WB:WBGene00305599 T13C2.8 No description available WB:WBGene00305600 T13E8.4 No description available WB:WBGene00305601 T13F2.16 No description available WB:WBGene00305602 T13H5.9 No description available WB:WBGene00305603 T16G12.15 No description available WB:WBGene00305604 T16G12.14 No description available WB:WBGene00305605 T17A3.14 No description available WB:WBGene00305606 T17H7.9 No description available WB:WBGene00305607 T19C11.4 No description available WB:WBGene00305608 T19D12.15 No description available WB:WBGene00305609 T20D3.15 No description available WB:WBGene00305610 T21B6.18 No description available WB:WBGene00305611 T22A3.14 No description available WB:WBGene00305612 T22A3.15 No description available WB:WBGene00305613 T22D1.23 No description available WB:WBGene00305614 T23B5.7 No description available WB:WBGene00305615 T23D8.14 No description available WB:WBGene00305616 T23G4.128 No description available WB:WBGene00305617 T23G5.12 No description available WB:WBGene00305618 T24B8.24 No description available WB:WBGene00305619 T24E12.15 No description available WB:WBGene00305620 T24F1.10 No description available WB:WBGene00305621 T24H5.2 No description available WB:WBGene00305622 T25D1.7 No description available WB:WBGene00305623 T25G12.16 No description available WB:WBGene00305624 T26A5.12 No description available WB:WBGene00305625 T26A5.13 No description available WB:WBGene00305626 T26E3.17 No description available WB:WBGene00305627 T27A8.10 No description available WB:WBGene00305628 T27E7.77 No description available WB:WBGene00305629 T27E7.78 No description available WB:WBGene00305630 T27F6.11 No description available WB:WBGene00305631 T28A8.9 No description available WB:WBGene00305632 T28F12.5 No description available WB:WBGene00305633 T28H11.32 No description available WB:WBGene00305634 W01F3.6 No description available WB:WBGene00305635 W02A11.9 No description available WB:WBGene00305636 W02B12.19 No description available WB:WBGene00305637 W02B9.5 No description available WB:WBGene00305638 W03D2.16 No description available WB:WBGene00305639 W03F11.8 No description available WB:WBGene00305640 W04A8.10 No description available WB:WBGene00305641 W05H9.6 No description available WB:WBGene00305642 W06D4.10 No description available WB:WBGene00305643 W06E11.8 No description available WB:WBGene00305644 W06E11.9 No description available WB:WBGene00305645 W08A12.6 No description available WB:WBGene00305646 W09D6.11 No description available WB:WBGene00305647 W09G3.17 No description available WB:WBGene00305648 W09G3.18 No description available WB:WBGene00305649 W09G3.19 No description available WB:WBGene00305650 W09H1.9 No description available WB:WBGene00305651 W10C4.3 No description available WB:WBGene00305652 W10C6.3 No description available WB:WBGene00305653 W10D9.8 No description available WB:WBGene00305654 Y104H12BR.2 No description available WB:WBGene00305655 Y104H12D.10 No description available WB:WBGene00305656 Y105E8A.52 No description available WB:WBGene00305657 Y105E8A.53 No description available WB:WBGene00305658 Y105E8A.54 No description available WB:WBGene00305659 Y105E8A.55 No description available WB:WBGene00305660 Y105E8B.16 No description available WB:WBGene00305661 Y105E8B.17 No description available WB:WBGene00305662 Y10G11A.93 No description available WB:WBGene00305663 Y110A7A.25 No description available WB:WBGene00305664 Y111B2A.38 No description available WB:WBGene00305665 Y111B2A.39 No description available WB:WBGene00305666 Y111B2A.40 No description available WB:WBGene00305667 Y111B2A.41 No description available WB:WBGene00305668 Y111B2A.42 No description available WB:WBGene00305669 Y111B2A.43 No description available WB:WBGene00305670 Y111B2A.44 No description available WB:WBGene00305671 Y113G7A.24 No description available WB:WBGene00305672 Y113G7A.25 No description available WB:WBGene00305673 Y113G7B.31 No description available WB:WBGene00305674 Y113G7B.32 No description available WB:WBGene00305675 Y116A8C.472 No description available WB:WBGene00305676 Y116A8C.473 No description available WB:WBGene00305677 Y116A8C.474 No description available WB:WBGene00305678 Y119D3B.28 No description available WB:WBGene00305679 Y119D3B.29 No description available WB:WBGene00305680 Y119D3B.30 No description available WB:WBGene00305681 Y119D3B.31 No description available WB:WBGene00305682 Y119D3B.32 No description available WB:WBGene00305683 Y11D7A.23 No description available WB:WBGene00305684 Y18D10A.31 No description available WB:WBGene00305685 Y18D10A.32 No description available WB:WBGene00305686 Y18D10A.33 No description available WB:WBGene00305687 Y18H1A.19 No description available WB:WBGene00305688 Y20F4.12 No description available WB:WBGene00305689 Y22D7AL.20 No description available WB:WBGene00305690 Y22D7AL.21 No description available WB:WBGene00305691 Y22D7AL.22 No description available WB:WBGene00305692 Y22D7AR.20 No description available WB:WBGene00305693 Y23H5A.12 No description available WB:WBGene00305694 Y25C1A.16 No description available WB:WBGene00305695 Y37D8A.30 No description available WB:WBGene00305696 Y37E11AR.10 No description available WB:WBGene00305697 Y37E3.31 No description available WB:WBGene00305698 Y37H2A.20 No description available WB:WBGene00305699 Y37H9A.9 No description available WB:WBGene00305700 Y37H9A.10 No description available WB:WBGene00305701 Y37H9A.11 No description available WB:WBGene00305702 Y38A8.4 No description available WB:WBGene00305703 Y38E10A.36 No description available WB:WBGene00305704 Y38F1A.14 No description available WB:WBGene00305705 Y38F2AR.23 No description available WB:WBGene00305706 Y38F2AR.24 No description available WB:WBGene00305707 Y38F2AR.25 No description available WB:WBGene00305708 Y38F2AR.26 No description available WB:WBGene00305709 Y38F2AR.27 No description available WB:WBGene00305710 Y38F2AR.28 No description available WB:WBGene00305711 Y38H8A.13 No description available WB:WBGene00305712 Y39A1A.32 No description available WB:WBGene00305713 Y39A3CL.16 No description available WB:WBGene00305714 Y39A3CR.12 No description available WB:WBGene00305715 Y39A3CR.13 No description available WB:WBGene00305716 Y39B6A.86 No description available WB:WBGene00305717 Y39B6A.87 No description available WB:WBGene00305718 Y39B6A.88 No description available WB:WBGene00305719 Y39B6A.89 No description available WB:WBGene00305720 Y39B6A.90 No description available WB:WBGene00305721 Y39E4B.18 No description available WB:WBGene00305722 Y39E4B.19 No description available WB:WBGene00305723 Y39F10B.2 No description available WB:WBGene00305724 Y39G10AR.33 No description available WB:WBGene00305725 Y39H10A.10 No description available WB:WBGene00305726 Y40B1A.7 No description available WB:WBGene00305727 Y40B1B.11 No description available WB:WBGene00305728 Y41C4A.33 No description available WB:WBGene00305729 Y41C4A.34 No description available WB:WBGene00305730 Y41D4B.37 No description available WB:WBGene00305731 Y41D4B.38 No description available WB:WBGene00305732 Y41D4B.39 No description available WB:WBGene00305733 Y42H9B.11 No description available WB:WBGene00305734 Y42H9B.12 No description available WB:WBGene00305735 Y42H9B.13 No description available WB:WBGene00305736 Y43F4B.15 No description available WB:WBGene00305737 Y43F8C.28 No description available WB:WBGene00305738 Y43F8C.29 No description available WB:WBGene00305739 Y43H11AL.9 No description available WB:WBGene00305740 Y43H11AL.10 No description available WB:WBGene00305741 Y43H11AL.11 No description available WB:WBGene00305742 Y45F10A.9 No description available WB:WBGene00305743 Y45F10A.10 No description available WB:WBGene00305744 Y45F10B.62 No description available WB:WBGene00305745 Y45F10D.140 No description available WB:WBGene00305746 Y46E12BL.12 No description available WB:WBGene00305747 Y46E12BL.13 No description available WB:WBGene00305748 Y46E12BM.2 No description available WB:WBGene00305749 Y46H3A.8 No description available WB:WBGene00305750 Y47D3A.36 No description available WB:WBGene00305751 Y47D3A.37 No description available WB:WBGene00305752 Y47G6A.40 No description available WB:WBGene00305753 Y47G6A.41 No description available WB:WBGene00305754 Y47H10A.9 No description available WB:WBGene00305755 Y47H9C.22 No description available WB:WBGene00305756 Y47H9C.23 No description available WB:WBGene00305757 Y48A5A.4 No description available WB:WBGene00305758 Y48A6B.19 No description available WB:WBGene00305759 Y48A6C.11 No description available WB:WBGene00305760 Y48A6C.12 No description available WB:WBGene00305761 Y48A6C.13 No description available WB:WBGene00305762 Y48A6C.14 No description available WB:WBGene00305763 Y48A6C.15 No description available WB:WBGene00305764 Y48C3A.26 No description available WB:WBGene00305765 Y48E1B.18 No description available WB:WBGene00305766 Y48G1A.8 No description available WB:WBGene00305767 Y48G1C.14 No description available WB:WBGene00305768 Y48G1C.15 No description available WB:WBGene00305769 Y48G8AL.21 No description available WB:WBGene00305770 Y48G8AL.22 No description available WB:WBGene00305771 Y48G9A.19 No description available WB:WBGene00305772 Y48G9A.20 No description available WB:WBGene00305773 Y48G9A.21 No description available WB:WBGene00305774 Y48G9A.22 No description available WB:WBGene00305775 Y49E10.38 No description available WB:WBGene00305776 Y49F6B.21 No description available WB:WBGene00305777 Y49F6B.22 No description available WB:WBGene00305778 Y50C1A.3 No description available WB:WBGene00305779 Y50D4A.13 No description available WB:WBGene00305780 Y50D4C.13 No description available WB:WBGene00305781 Y50D4C.14 No description available WB:WBGene00305782 Y50D7A.19 No description available WB:WBGene00305783 Y50D7A.20 No description available WB:WBGene00305784 Y50D7A.21 No description available WB:WBGene00305785 Y50D7A.22 No description available WB:WBGene00305786 Y51A2D.42 No description available WB:WBGene00305787 Y51A2D.43 No description available WB:WBGene00305788 Y51A2D.44 No description available WB:WBGene00305789 Y51F10.16 No description available WB:WBGene00305790 Y51H4A.942 No description available WB:WBGene00305791 Y51H4A.943 No description available WB:WBGene00305792 Y52B11A.22 No description available WB:WBGene00305793 Y53C12B.10 No description available WB:WBGene00305794 Y53F4A.6 No description available WB:WBGene00305795 Y53F4A.7 No description available WB:WBGene00305796 Y53F4B.64 No description available WB:WBGene00305797 Y53F4B.65 No description available WB:WBGene00305798 Y53G8AR.11 No description available WB:WBGene00305799 Y53G8AR.12 No description available WB:WBGene00305800 Y53G8B.6 No description available WB:WBGene00305801 Y53G8B.7 No description available WB:WBGene00305802 Y53G8B.8 No description available WB:WBGene00305803 Y53G8B.9 No description available WB:WBGene00305804 Y53G8B.10 No description available WB:WBGene00305805 Y53G8B.11 No description available WB:WBGene00305806 Y53G8B.12 No description available WB:WBGene00305807 Y53H1A.11 No description available WB:WBGene00305808 Y53H1C.12 No description available WB:WBGene00305809 Y53H1C.13 No description available WB:WBGene00305810 Y54E10A.30 No description available WB:WBGene00305811 Y54E10A.31 No description available WB:WBGene00305812 Y54E2A.15 No description available WB:WBGene00305813 Y54E5A.9 No description available WB:WBGene00305814 Y54E5B.8 No description available WB:WBGene00305815 Y54F10AL.4 No description available WB:WBGene00305816 Y54F10AL.5 No description available WB:WBGene00305817 Y54F10AL.6 No description available WB:WBGene00305818 Y54F10AL.7 No description available WB:WBGene00305819 Y54F10BM.24 No description available WB:WBGene00305820 Y54G11A.24 No description available WB:WBGene00305822 Y54G11A.22 No description available WB:WBGene00305823 Y54G11A.23 No description available WB:WBGene00305824 Y54G2A.78 No description available WB:WBGene00305825 Y54G2A.79 No description available WB:WBGene00305826 Y54G2A.80 No description available WB:WBGene00305827 Y54H5A.7 No description available WB:WBGene00305828 Y55B1BM.2 No description available WB:WBGene00305829 Y55B1BR.9 No description available WB:WBGene00305830 Y55B1BR.10 No description available WB:WBGene00305831 Y55F3AM.24 No description available WB:WBGene00305832 Y55F3AR.5 No description available WB:WBGene00305833 Y55F3BL.7 No description available WB:WBGene00305834 Y55F3BR.20 No description available WB:WBGene00305835 Y56A3A.42 No description available WB:WBGene00305836 Y56A3A.43 No description available WB:WBGene00305837 Y56A3A.44 No description available WB:WBGene00305838 Y57A10A.45 No description available WB:WBGene00305839 Y57A10A.46 No description available WB:WBGene00305840 Y57A10A.47 No description available WB:WBGene00305841 Y57A10B.11 No description available WB:WBGene00305842 Y59A8B.41 No description available WB:WBGene00305843 Y59A8B.42 No description available WB:WBGene00305844 Y59A8B.43 No description available WB:WBGene00305845 Y59A8B.44 No description available WB:WBGene00305846 Y59A8B.45 No description available WB:WBGene00305847 Y59A8B.46 No description available WB:WBGene00305848 Y60A3A.37 No description available WB:WBGene00305849 Y60A3A.38 No description available WB:WBGene00305850 Y60A3A.39 No description available WB:WBGene00305851 Y60A3A.40 No description available WB:WBGene00305852 Y60A3A.41 No description available WB:WBGene00305853 Y61A9LA.14 No description available WB:WBGene00305854 Y61A9LA.15 No description available WB:WBGene00305855 Y61A9LA.16 No description available WB:WBGene00305856 Y63D3A.13 No description available WB:WBGene00305857 Y63D3A.14 No description available WB:WBGene00305858 Y65B4BL.13 No description available WB:WBGene00305859 Y67D8A.11 No description available WB:WBGene00305860 Y67D8C.24 No description available WB:WBGene00305861 Y67D8C.25 No description available WB:WBGene00305862 Y67D8C.26 No description available WB:WBGene00305863 Y69A2AR.52 No description available WB:WBGene00305864 Y69A2AR.53 No description available WB:WBGene00305865 Y69A2AR.54 No description available WB:WBGene00305866 Y69A2AR.55 No description available WB:WBGene00305867 Y69A2AR.56 No description available WB:WBGene00305868 Y69E1A.16 No description available WB:WBGene00305869 Y69H2.29 No description available WB:WBGene00305870 Y69H2.30 No description available WB:WBGene00305871 Y69H2.31 No description available WB:WBGene00305872 Y69H2.32 No description available WB:WBGene00305873 Y69H2.33 No description available WB:WBGene00305874 Y6B3A.2 No description available WB:WBGene00305875 Y6B3B.16 No description available WB:WBGene00305876 Y6D1A.4 No description available WB:WBGene00305877 Y71A12B.34 No description available WB:WBGene00305878 Y71A12B.35 No description available WB:WBGene00305879 Y71F9AM.10 No description available WB:WBGene00305880 Y71G10AR.6 No description available WB:WBGene00305881 Y71G12A.6 No description available WB:WBGene00305882 Y71G12A.7 No description available WB:WBGene00305883 Y71G12B.45 No description available WB:WBGene00305884 Y71G12B.46 No description available WB:WBGene00305885 Y71G12B.47 No description available WB:WBGene00305886 Y73B3A.33 No description available WB:WBGene00305887 Y73B6BL.291 No description available WB:WBGene00305888 Y73B6BL.292 No description available WB:WBGene00305889 Y73F8A.1177 No description available WB:WBGene00305890 Y74C10AM.2 No description available WB:WBGene00305891 Y75B8A.64 No description available WB:WBGene00305892 Y75B8A.65 No description available WB:WBGene00305893 Y76B12C.12 No description available WB:WBGene00305894 Y76B12C.13 No description available WB:WBGene00305895 Y76B12C.14 No description available WB:WBGene00305896 Y76B12C.15 No description available WB:WBGene00305897 Y76B12C.16 No description available WB:WBGene00305898 Y77E11A.24 No description available WB:WBGene00305899 Y77E11A.25 No description available WB:WBGene00305900 Y77E11A.26 No description available WB:WBGene00305901 Y79H2A.15 No description available WB:WBGene00305902 Y80D3A.17 No description available WB:WBGene00305903 Y80D3A.18 No description available WB:WBGene00305904 Y80D3A.19 No description available WB:WBGene00305905 Y80D3A.20 No description available WB:WBGene00305906 Y80D3A.21 No description available WB:WBGene00305907 Y80D3A.22 No description available WB:WBGene00305908 Y82E9BR.33 No description available WB:WBGene00305909 Y82E9BR.34 No description available WB:WBGene00305910 Y82E9BR.35 No description available WB:WBGene00305911 Y82E9BR.36 No description available WB:WBGene00305912 Y87G2A.27 No description available WB:WBGene00305913 Y87G2A.28 No description available WB:WBGene00305914 Y87G2A.29 No description available WB:WBGene00305915 Y87G2A.30 No description available WB:WBGene00305916 Y92C3B.5 No description available WB:WBGene00305917 Y92H12A.9 No description available WB:WBGene00305918 Y92H12A.10 No description available WB:WBGene00305919 Y92H12A.11 No description available WB:WBGene00305920 Y92H12A.12 No description available WB:WBGene00305921 Y92H12A.13 No description available WB:WBGene00305922 Y92H12BL.8 No description available WB:WBGene00305923 Y92H12BL.9 No description available WB:WBGene00305924 Y92H12BL.10 No description available WB:WBGene00305925 Y92H12BR.9 No description available WB:WBGene00305926 Y92H12BR.10 No description available WB:WBGene00305927 Y92H12BR.11 No description available WB:WBGene00305928 Y95B8A.19 No description available WB:WBGene00305929 Y95B8A.20 No description available WB:WBGene00305930 Y95B8A.21 No description available WB:WBGene00305931 Y95B8A.22 No description available WB:WBGene00305932 ZC308.7 No description available WB:WBGene00305933 ZC308.8 No description available WB:WBGene00305934 ZC518.9 No description available WB:WBGene00305935 ZK1010.13 No description available WB:WBGene00305936 ZK1010.14 No description available WB:WBGene00305937 ZK1098.14 No description available WB:WBGene00305938 ZK1128.11 No description available WB:WBGene00305939 ZK1307.10 No description available WB:WBGene00305940 ZK1307.11 No description available WB:WBGene00305941 ZK177.14 No description available WB:WBGene00305942 ZK250.16 No description available WB:WBGene00305943 ZK355.9 No description available WB:WBGene00305944 ZK370.12 No description available WB:WBGene00305945 ZK418.14 No description available WB:WBGene00305946 ZK484.13 No description available WB:WBGene00305947 ZK484.14 No description available WB:WBGene00305948 ZK484.15 No description available WB:WBGene00305949 ZK484.16 No description available WB:WBGene00305950 ZK484.17 No description available WB:WBGene00305951 ZK593.15 No description available WB:WBGene00305952 ZK643.14 No description available WB:WBGene00305953 ZK742.9 No description available WB:WBGene00305954 ZK795.10 No description available WB:WBGene00305955 ZK858.11 No description available WB:WBGene00305956 ZK892.11 No description available WB:WBGene00305957 ZK938.13 No description available WB:WBGene00305970 C09E7.11 Is affected by mrps-5 based on microarray studies. Is affected by dibromoacetic acid and adsorbable organic bromine compound based on microarray studies. WB:WBGene00305979 C18H2.8 No description available WB:WBGene00305980 C18H2.9 Is affected by isp-1 based on microarray studies. Is affected by Diazinon and allantoin based on microarray studies. WB:WBGene00305981 C39B5.16 No description available WB:WBGene00305991 E02H9.12 Is affected by tdp-1; nhr-25; and nuo-6 based on microarray studies. Is affected by Atrazine; fluoranthene; and Microcystin-LR based on microarray studies. WB:WBGene00305992 E02H9.13 No description available WB:WBGene00305993 H04D03.7 No description available WB:WBGene00305994 H04J21.4 Is affected by bcf-1 and slr-2 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Ubiquitin-like domain superfamily. WB:WBGene00305995 H09G03.4 No description available WB:WBGene00305996 H09G03.5 No description available WB:WBGene00305997 cTel54X.2 No description available WB:WBGene00305998 R148.8 Is affected by sir-2.1 based on microarray studies. WB:WBGene00305999 T12A2.21 No description available WB:WBGene00306000 T12B5.18 Is affected by sir-2.1; lin-14; and lin-4 based on microarray studies. WB:WBGene00306001 T16G12.13 Is affected by several genes including dpy-10; pmk-1; and isp-1 based on microarray studies. Is affected by six chemicals including Tamoxifen; Quercetin; and Hydrolyzable Tannins based on RNA-seq and microarray studies. WB:WBGene00306002 T24C4.10 No description available WB:WBGene00306003 W04B5.8 Enriched in neurons and retrovesicular ganglion based on microarray studies. Is affected by several genes including rde-4; hpl-2; and his-24 based on microarray studies. Is affected by seven chemicals including Acrylamide; Atrazine; and Humic Substances based on microarray studies. WB:WBGene00306004 Y39A1A.31 Is affected by sir-2.1 based on microarray studies. WB:WBGene00306005 Y39A3B.8 No description available WB:WBGene00306012 Y54F10BM.21 No description available WB:WBGene00306013 Y54F10BM.22 No description available WB:WBGene00306014 Y54F10BM.23 No description available WB:WBGene00306062 K07C10.8 No description available WB:WBGene00306066 Y54G11A.20 No description available WB:WBGene00306069 F23F12.17 Is affected by several genes including daf-2; sir-2.1; and lin-35 based on RNA-seq and microarray studies. Is affected by Humic Substances and Sirolimus based on microarray studies. WB:WBGene00306070 W02A2.12 No description available WB:WBGene00306071 mha-1 No description available WB:WBGene00306072 mha-2 No description available WB:WBGene00306073 mha-3 No description available WB:WBGene00306076 Y53C10A.25 No description available WB:WBGene00306078 Y51H7C.42 Is affected by mrps-5 based on microarray studies. Is affected by triclosan and nitroguanidine based on microarray studies. WB:WBGene00306079 vab-18 No description available WB:WBGene00306080 Y71F9AM.11 No description available WB:WBGene00306081 T21G5.12 Enriched in intestine based on microarray studies. Is affected by several genes including lin-4; lin-14; and sir-2.1 based on microarray studies. Is affected by five chemicals including resveratrol; Chlorpyrifos; and paraquat based on microarray studies. WB:WBGene00306121 Y48G1BM.10 Enriched in neurons and retrovesicular ganglion based on microarray studies. Is affected by several genes including isp-1; alg-1; and mut-2 based on microarray studies. WB:WBGene00306122 T22B2.12 No description available WB:WBGene00306123 Y97E10C.2 No description available WB:WBGene00306124 W04B5.9 Is affected by sir-2.1 based on microarray studies. Is affected by Acrylamide based on microarray studies. WB:WBGene00306125 F58B6.11 Enriched in neurons and retrovesicular ganglion based on microarray studies. Is affected by tdp-1 based on microarray studies. Is affected by Atrazine; cadmium; and nitroguanidine based on microarray studies. WB:WBGene00306126 cone-1 Predicted to be involved in intra-Golgi vesicle-mediated transport. Predicted to be located in Golgi membrane. WB:WBGene00306131 Y34B4A.20 No description available WB:WBGene00306132 F54D10.10 Is affected by several genes including dpy-10; pmk-1; and fbf-1 based on microarray studies. Is affected by five chemicals including Quercetin; Hydrolyzable Tannins; and paraquat based on microarray studies. WB:WBGene00306133 azyx-1 Is affected by sir-2.1 based on microarray studies. WB:WBGene00306134 srlf-8 Is affected by sir-2.1 and daf-2 based on microarray studies. Is affected by Chlorpyrifos; dafa#1; and Sirolimus based on microarray studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, cation-binding domain and SXP/RAL-2 family protein Ani s 5-like, metal-binding domain.