cur_paper cur_datatype atp cur_curator cur_selcomment cur_txtcomment cur_timestamp oa_source in_curation_status 00000159 catalyticact ATP:0000061 two1843 Curated for GO (by WB) motor activity 2021-05-19 07:28:55.537932-07 0 1 00000159 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-10 11:05:29.968652-07 1 1 00000321 geneint ATP:0000068 two712 2014-12-12 16:39:04.965792-08 1 1 00000654 catalyticact ATP:0000061 two1843 Curated for GO (by WB) RNA polymerase II activity 2021-05-19 07:28:55.557904-07 0 1 00000735 catalyticact ATP:0000061 two1843 Curated for GO (by WB) choline acyltransferase activity 2021-05-19 07:29:08.428197-07 0 1 00001039 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 12:56:27.02055-08 0 1 00001250 geneprod ATP:0000069 two1843 Curated for GO (by WB) cAMP-dependent protein kinase complex; cited as unpublished observations in Discussion. 2018-06-21 17:51:56.3194-07 1 1 00001354 catalyticact ATP:0000061 two1843 Curated for GO (by WB) RNA polymerase II activity 2021-05-19 07:28:55.560535-07 0 1 00001380 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein kinase activity (GO:0004672); casein as in vitro substrate 2024-05-28 09:07:10.41644-07 0 1 00001666 catalyticact ATP:0000061 two1843 Curated for GO (by WB) GTPase activity 2021-05-19 07:29:08.433987-07 0 1 00001666 geneprod ATP:0000069 two1843 Curated for GO (by WB) curation negative, GTP binding 2018-04-25 12:15:26.001763-07 1 1 00001744 catalyticact ATP:0000061 two1843 Curated for GO (by WB) GTPase activity 2021-05-19 07:29:08.439124-07 0 1 00001744 geneprod ATP:0000069 two1843 Curated for GO (by GOA) curation negative, GTP binding 2018-04-25 12:15:26.013885-07 1 1 00001790 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-25 12:15:26.02504-07 1 1 00001823 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, AT DNA binding 2018-04-25 12:15:26.036092-07 1 1 00001839 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-12 08:30:06.586995-07 1 1 00001857 geneprod ATP:0000069 two1843 Curated for GO (by WB) inter-species PPI 2018-04-24 11:02:25.023076-07 1 1 00001870 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) IMP for protein kinase activity 2023-11-06 12:57:59.261417-08 0 1 00001912 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-09 13:55:34.140799-07 1 1 00001929 catalyticact ATP:0000061 two1843 Curated for GO (by WB) acetylcholinesterase activity 2021-05-19 07:29:08.444076-07 0 1 00002014 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity (GO:0004674) - IDA 2023-08-07 05:55:37.486169-07 0 1 00002049 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 15:19:51.566206-08 0 1 00002150 catalyticact ATP:0000061 two1843 Curated for GO (by WB) MAP kinase kinase activity - human ERK1 as substrate 2024-06-03 07:54:31.562622-07 0 1 00002174 geneprod ATP:0000069 two1843 Curated for GO (by WB) curation negative, caicium binding 2018-04-25 12:15:26.047045-07 1 1 00002194 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ornithine decarboxylase activity 2021-05-19 07:49:30.315305-07 0 1 00002223 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-26 16:11:59.702093-07 1 1 00002242 catalyticact ATP:0000061 two1843 Curated for GO (by WB) methyltransferase activity 2021-05-19 07:49:30.318062-07 0 1 00002294 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:10:44.70317-08 0 1 00002313 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ubiquitin conjugating enzyme activity 2021-05-19 07:49:30.320637-07 0 1 00002393 catalyticact ATP:0000061 two1843 Curated for GO (by WB) endopeptidase activity 2021-05-19 07:49:36.255305-07 0 1 00002424 geneprod ATP:0000069 two1843 Curated for GO (by WB) phosphatidylserine binding 2014-09-02 10:56:06.401568-07 1 1 00002435 catalyticact ATP:0000061 two1843 Curated for GO (by WB) topoisomerase activity 2021-05-19 07:49:30.323187-07 0 1 00002452 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-25 10:52:23.306354-07 1 1 00002454 catalyticact ATP:0000061 two1843 Curated for GO (by WB) endopeptidase activity 2021-05-19 07:49:36.26019-07 0 1 00002472 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 12:22:35.195116-08 0 1 00002507 geneprod ATP:0000069 two1843 Curated for GO (by WB) tubulin binding 2018-04-26 16:11:59.713441-07 1 1 00002544 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) protein kinase activity 2022-04-06 13:47:39.966415-07 0 1 00002585 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:28:44.186276-08 0 1 00002601 geneprod ATP:0000069 two1843 Curated for GO (by WB) microtubule binding 2014-09-09 13:45:52.437359-07 1 1 00002642 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein kinase activity 2021-05-19 07:49:30.325697-07 0 1 00002716 catalyticact ATP:0000061 two1843 Curated for GO (by WB) fat-1 omega-3 fatty acid desaturase activity 2026-04-07 12:45:09.092486-07 0 1 00002733 catalyticact ATP:0000061 two1843 Curated for GO (by WB) pkc-2 calcium,diacylglycerol-dependent serine/threonine kinase activity 2024-06-05 09:46:45.935464-07 0 1 00002785 geneprod ATP:0000069 two1843 Curated for GO (by WB) unfolded protein binding, curation negative 2018-04-25 10:52:23.317383-07 1 1 00002796 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-02 11:27:48.364391-07 1 1 00002804 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:30:16.673291-08 0 1 00002806 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:18:01.314916-08 0 1 00002809 catalyticact ATP:0000061 two1843 Curated for GO (by WB) polynucleotide phosphatase activity 2021-05-19 07:58:05.782282-07 0 1 00002821 catalyticact ATP:0000061 two1843 Curated for GO (by WB) guanylate cyclase activity 2021-05-19 08:06:03.321344-07 0 1 00002826 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region, sequence-specific DNA binding 2018-04-24 15:33:28.410702-07 1 1 00002839 catalyticact ATP:0000061 two1843 Curated for GO (by WB) guanylate cyclase activity 2021-05-19 08:06:03.337341-07 0 1 00002841 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein kinase activity 2021-05-19 08:06:06.461985-07 0 1 00002849 transporter ATP:0000062 two1843 Curated for GO (by WB) delayed rectifier potassium channel activity 2023-11-08 07:52:08.232466-08 0 1 00002860 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:03:28.556632-08 0 1 00002889 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-05-03 11:01:14.922988-07 1 1 00002904 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein kinase activity 2021-05-19 10:12:46.563715-07 0 1 00002908 catalyticact ATP:0000061 two1843 Curated for GO (by WB) endopeptidase activity 2021-05-19 10:12:49.568499-07 0 1 00002928 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ubiquitin conjugating enzyme activity 2021-05-19 10:12:46.569866-07 0 1 00002943 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:48:02.848397-08 0 1 00002989 catalyticact ATP:0000061 two1843 Curated for GO (by WB) pkc-3 protein serine/threonine kinase activity 2024-06-07 08:01:18.681934-07 0 1 00003027 geneprod ATP:0000069 two1843 Curated for GO (by WB) Inter-species PPI, Rac guanyl-nucleotide exchange factor activity 2018-05-03 10:48:46.85433-07 1 1 00003028 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, DNA binding 2018-04-26 16:11:59.720842-07 1 1 00003035 catalyticact ATP:0000061 two1843 Curated for GO (by WB) superoxide dismutase activity 2021-05-19 10:12:46.572546-07 0 1 00003042 catalyticact ATP:0000061 two1843 Curated for GO (by WB) polypeptide N-acetylgalactosaminyltransferase activity 2021-05-20 11:48:10.836788-07 0 1 00003054 geneprod ATP:0000069 two1843 Curated for GO (by WB) CAP bindng, PRI 2018-04-24 14:58:22.09761-07 1 1 00003068 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding RNA polymerase II transcription factor activity 2018-04-26 16:15:50.764681-07 1 1 00003080 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:09:29.067187-08 0 1 00003081 geneprod ATP:0000069 two1843 PDI 2019-07-25 17:11:07.423396-07 1 1 00003082 catalyticact ATP:0000061 two1843 Curated for GO (by WB) transmembrane receptor protein tyrosine phosphatase activity 2021-05-20 11:48:16.731939-07 0 1 00003086 catalyticact ATP:0000061 two1843 Curated for GO (by WB) sphingomyelin phosphodiesterase activity 2021-05-20 11:48:16.737014-07 0 1 00003088 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-26 16:15:50.772163-07 1 1 00003126 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-30 17:47:37.119764-08 0 1 00003150 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Curated with the transporter term in GO MF. 2025-01-31 14:21:42.111007-08 0 1 00003150 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:21:42.10758-08 0 1 00003174 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-24 15:33:28.424239-07 1 1 00003181 catalyticact ATP:0000061 two1843 Curated for GO (by WB) alpha-(1->3)-fucosyltransferase activity 2021-05-20 11:48:10.858529-07 0 1 00003211 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:54:17.474759-08 0 1 00003230 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:07:47.020523-08 0 1 00003235 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:30:37.903178-08 0 1 00003241 catalyticact ATP:0000061 two1843 Curated for GO (by WB) aminopeptidase activity 2021-05-20 11:48:10.861245-07 0 1 00003262 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-26 22:50:49.5663-07 1 1 00003269 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein-tyrosine sulfotransferase activity 2021-05-20 11:48:10.863923-07 0 1 00003285 otherexpr ATP:0000041 two12028 Done. expr708 2022-07-05 05:36:57.749891-07 1 1 00003292 geneprod ATP:0000069 two1843 Curated for GO (by WB) copper chaperone activity 2014-09-02 11:29:20.734857-07 1 1 00003348 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:23:39.317646-08 0 1 00003352 catalyticact ATP:0000061 two1843 Curated for GO (by WB) alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 2021-05-20 11:48:10.866877-07 0 1 00003390 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, polynucleotide binding 2018-04-26 22:50:49.574052-07 1 1 00003407 geneprod ATP:0000069 two1843 Curated for GO (by WB) Inter-species PPI, calmodulin binding 2018-04-26 23:17:17.224459-07 1 1 00003407 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:10:25.001044-08 0 1 00003430 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:29:45.397301-08 0 1 00003432 geneprod ATP:0000069 two1843 Curated for GO (by WB) curation negative, amine binding; serotonin binding 2018-04-26 23:17:17.235957-07 1 1 00003511 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 13:43:05.85513-08 0 1 00003526 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ATP-dependent microtubule motor activity, plus-end-directed 2021-05-20 11:48:10.869511-07 0 1 00003526 geneprod ATP:0000069 two1843 Curated for GO (by WB) microtubule binding 2014-09-10 07:06:59.110172-07 1 1 00003529 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-10 07:09:18.060484-07 1 1 00003553 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-10 07:00:17.680676-07 1 1 00003556 catalyticact ATP:0000061 two1843 Curated for GO (by WB) metallopeptidase activity 2021-05-20 11:48:10.872468-07 0 1 00003570 catalyticact ATP:0000061 two1843 Curated for GO (by WB) lit-1 protein serine/threonine kinase activity 2024-06-10 07:41:44.800162-07 0 1 00003574 catalyticact ATP:0000061 two1843 Curated for GO (by WB) mom-4 protein serine/threonine kinase activity; mammalian subsstrates 2024-06-10 08:04:46.336948-07 0 1 00003602 geneprod ATP:0000069 two1843 Curated for GO (by WB) calcium-dependent phospholipid binding 2014-09-02 11:09:41.041359-07 1 1 00003607 catalyticact ATP:0000061 two1843 Curated for GO (by WB) jkk-1 and jnk-1 JUN kinase kinase and JUN kinase activities and gpdh-2 dehydrogenase activity 2024-06-11 08:07:45.595918-07 0 1 00003619 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-26 23:17:17.246924-07 1 1 00003625 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ckk-1 and cmk-1 calmodulin-dependent protein kinase activity 2024-06-12 07:01:10.954586-07 0 1 00003675 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, DNA binding 2018-04-26 23:17:17.259278-07 1 1 00003697 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ATP-dependent diacylglycerol kinase activity 2023-11-06 06:53:53.481032-08 0 1 00003698 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-26 23:17:17.268287-07 1 1 00003733 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-26 23:17:17.276566-07 1 1 00003820 catalyticact ATP:0000061 two1843 Curated for GO (by WB) peptidyl-prolyl cis-trans isomerase activity 2023-11-03 13:04:56.630745-07 0 1 00003875 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PXF-1 Ras/Rap GEF activity 2021-12-10 12:01:17.389413-08 0 1 00003875 geneprod ATP:0000069 two1843 Curated for GO (by GOA) Rap guanyl-nucleotide exchange factor activity 2014-09-10 07:30:34.924608-07 1 1 00003890 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:51:44.845858-08 0 1 00003954 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:24:35.766726-08 0 1 00003967 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PEK-1 eukaryotic translation initiation factor 2alpha kinase activity; mixed species uses S. cerevisiae eIF2A 2024-07-18 10:40:50.775713-07 0 1 00003971 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:41:33.044457-08 0 1 00003973 catalyticact ATP:0000061 two1843 Curated for GO (by WB) catalase activity; peroxidase activity 2023-11-03 12:56:39.103714-07 0 1 00003987 geneprod ATP:0000069 two1843 Curated for GO (by WB) CAP binding, PRI 2018-04-24 14:59:44.341498-07 1 1 00004180 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:50:05.880984-08 0 1 00004196 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-03-15 10:41:42.931521-07 0 1 00004212 geneprod ATP:0000069 two1843 Curated for GO (by GOA) curation negative, cell adhesion molecule binding 2018-04-26 23:35:16.457254-07 1 1 00004244 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-26 23:35:16.468925-07 1 1 00004251 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 12:55:33.411766-08 0 1 00004256 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-26 23:35:16.479281-07 1 1 00004274 geneprod ATP:0000069 two1843 Curated for GO (by WB) galactoside binding 2014-09-10 07:45:17.567955-07 1 1 00004324 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II distal enhancer sequence-specific DNA binding 2018-04-26 23:35:16.490719-07 1 1 00004344 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:40:14.046303-08 0 1 00004376 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:57:31.297728-08 0 1 00004395 geneprod ATP:0000069 two1843 Curated for GO (by WB) peroxisome targeting sequence binding 2014-09-10 07:51:27.95483-07 1 1 00004402 rnai ATP:0000082 two2987 Large scale RNAi paper (2287 RNAi objects); not in RNAi OA 2013-01-14 14:17:43.10724-08 1 1 00004403 rnai ATP:0000082 two2987 Large scale RNAi paper (2584 RNAi objects); not in RNAi OA 2013-01-14 14:19:31.992814-08 1 1 00004415 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:50:11.02146-08 0 1 00004468 geneprod ATP:0000069 two1843 Curated for GO (by WB) curation negative, calcium ion binding 2018-04-27 10:36:26.106201-07 1 1 00004476 catalyticact ATP:0000061 two1843 Curated for GO (by WB) SPK-1 protein serine/threonine kinase activity on RPS-3 2024-07-18 10:57:05.587986-07 0 1 00004492 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-24 15:33:28.436254-07 1 1 00004537 geneprod ATP:0000069 two1843 Curated for GO (by WB) Protein-carbohydrate interaction 2018-04-24 14:06:35.742846-07 1 1 00004552 catalyticact ATP:0000061 two1843 Curated for GO (by WB) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2023-11-06 06:59:01.502541-08 0 1 00004578 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-10 07:56:14.303492-07 1 1 00004619 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:33:13.80643-08 0 1 00004639 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) PKC-3 protein serine/threonine kinase activity 2024-07-19 08:12:48.151405-07 0 1 00004651 rnai ATP:0000082 two2987 Large scale RNAi paper (2479 RNAi objects); not in RNAi OA 2013-01-14 14:25:39.779058-08 1 1 00004656 geneprod ATP:0000069 two1843 Curated for GO (by WB), Curated for BioGRID (by WB) Inter-species PPI, PDI 2018-04-24 12:56:42.498543-07 1 1 00004659 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:12:25.779004-08 0 1 00004699 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ZYG-1 autophosphorylation - protein serine/threonine kinase activity 2024-07-15 12:04:55.848064-07 0 1 00004720 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PDK-1 and W04B5.5 protein serine/threonine kinase activity 2024-07-11 14:24:24.465056-07 0 1 00004743 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-13 14:01:53.080964-08 0 1 00004809 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:48:07.225245-08 0 1 00004826 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-27 11:07:18.875777-07 1 1 00004841 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 15:06:27.042263-08 0 1 00004858 geneprod ATP:0000069 two1843 Curated for GO (by WB) curation negative, calcium ion binding 2018-04-27 11:13:16.786083-07 1 1 00004889 catalyticact ATP:0000061 two1843 Curated for GO (by WB) C. elegans JNK-1 phosphorylating mammalian substrates 2024-07-09 07:04:37.470936-07 0 1 00004946 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 12:58:24.352379-08 0 1 00004946 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, curation negative, damaged DNA binding 2018-04-27 11:13:16.792765-07 1 1 00004954 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-27 11:13:16.798994-07 1 1 00004959 geneprod ATP:0000069 two1843 Curated for GO (by WB) inter-species PPI, Rho guanyl-nucleotide exchange factor activity 2018-04-27 11:21:27.668242-07 1 1 00004979 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:37:46.84173-08 0 1 00005015 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:41:43.153068-08 0 1 00005028 catalyticact ATP:0000061 two1843 Curated for GO (by WB) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity 2023-11-06 09:56:57.955131-08 0 1 00005044 catalyticact ATP:0000061 two1843 Curated for GO (by WB) endoribonuclease and kinase activities 2023-11-06 08:39:36.750701-08 0 1 00005101 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:12:16.70588-08 0 1 00005102 catalyticact ATP:0000061 two1843 Curated for GO (by WB) NSY-1, SEK-1 protein serine/threonine kinase activity and MAPK terms 2024-07-22 07:40:30.025187-07 0 1 00005147 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:07:06.271244-08 0 1 00005168 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-10 08:34:11.089359-07 1 1 00005199 geneprod ATP:0000069 two1843 Curated for GO (by WB) microtubule binding 2014-09-10 08:21:16.42264-07 1 1 00005226 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-27 11:42:59.211914-07 1 1 00005228 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, regulatory region DNA binding 2018-04-27 11:42:59.21921-07 1 1 00005311 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 13:50:24.105244-08 0 1 00005385 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:38:11.083216-08 0 1 00005385 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, RNA binding 2018-04-27 12:14:45.04947-07 1 1 00005390 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 12:59:10.808773-08 0 1 00005401 catalyticact ATP:0000061 two1843 Curated for GO (by WB) succinyl-CoA hydrolase activity and others 2023-11-06 09:54:39.448692-08 0 1 00005428 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, mRNA binding 2018-04-27 12:14:45.061331-07 1 1 00005453 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein phosphatase activity 2021-06-11 13:55:42.920347-07 0 1 00005471 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 15:15:15.988643-08 0 1 00005497 geneprod ATP:0000069 two1843 Curated for GO (by WB) CAP bindng, PRI 2018-04-24 15:00:48.724968-07 1 1 00005558 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-13 14:02:46.75709-08 0 1 00005574 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:19:00.821593-08 0 1 00005591 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:08:54.017967-08 0 1 00005607 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-10 09:30:24.520339-07 1 1 00005635 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity 2023-11-06 12:25:54.336586-08 0 1 00005654 rnai ATP:0000082 two2987 Large scale RNAi paper (14253 RNAi objects); not in RNAi OA 2013-01-14 14:25:39.901575-08 1 1 00005703 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 12:57:36.316001-08 0 1 00005703 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, RNA binding 2018-04-27 12:14:45.072295-07 1 1 00005704 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-07 12:29:43.24945-08 0 1 00005721 catalyticact ATP:0000061 two1843 Curated for GO (by WB) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity 2023-11-06 12:24:47.604808-08 0 1 00005726 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:43:42.198617-08 0 1 00005786 geneprod ATP:0000069 two1843 SVM Positive, Curation Negative Experimental results were negative: CHE-13 and HIPR-1/HIP-1 do not physically interact. 2014-08-04 10:45:36.484863-07 1 1 00005790 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-03-16 10:30:43.277337-07 0 1 00005801 transporter ATP:0000062 two1843 2025-01-30 17:26:21.643786-08 0 1 00005826 geneprod ATP:0000069 two1843 Curated for GO (by WB) curation negative, ATP binding 2018-04-27 12:20:52.241835-07 1 1 00005845 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:59:28.613473-08 0 1 00005857 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-13 14:08:35.744229-08 0 1 00005872 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 13:22:11.982469-08 0 1 00005888 catalyticact ATP:0000061 two1843 Curated for GO (by WB) glutathione transferase activity 2023-11-09 15:01:13.108094-08 0 1 00005916 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-13 13:57:57.817129-08 0 1 00005919 geneprod ATP:0000069 two1843 Curated for GO (by WB) DNA binding 2014-09-10 09:48:14.058715-07 1 1 00005978 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-13 14:05:38.56728-08 0 1 00006000 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, telomeric DNA binding 2018-04-30 12:38:43.209365-07 1 1 00006024 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-27 12:23:56.329954-07 1 1 00006041 transporter ATP:0000062 two1843 Curated for GO (by WB) 2021-04-12 08:09:40.154175-07 0 1 00006046 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:36:49.14417-08 0 1 00006108 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-10 10:04:23.026206-07 1 1 00006127 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:39:31.534877-08 0 1 00006128 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity 2023-11-06 09:02:48.962853-08 0 1 00006128 geneprod ATP:0000069 two1843 Curated for GO (by GOA) curation negative, RNA 7-methylguanosine cap binding 2018-04-27 13:09:54.267506-07 1 1 00006173 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:50:58.382907-08 0 1 00006178 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-04-27 13:09:54.279354-07 1 1 00006181 catalyticact ATP:0000061 two1843 Curated for GO (by WB) histone H3 kinase activity (GO:0140996) 2023-08-02 06:30:24.926592-07 0 1 00006186 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:32:09.441358-08 0 1 00006229 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) 2016-11-30 15:14:25.916821-08 0 1 00006241 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI. double-stranded DNA binding 2018-04-24 15:33:28.449-07 1 1 00006260 geneprod ATP:0000069 two1843 Curated for GO (by WB) RRI, mRNA binding 2018-04-27 13:09:54.290184-07 1 1 00006309 catalyticact ATP:0000061 two1843 Curated for GO (by WB) nucleotide phosphatase activity 2023-11-09 14:59:35.930901-08 0 1 00006389 geneprod ATP:0000069 two1843 Curated for GO (by WB) curation negative, amine binding 2018-04-27 13:09:54.301138-07 1 1 00006395 rnai ATP:0000082 two2987 Large scale RNAi paper (3230 RNAi objects); not in RNAi OA 2013-01-14 14:25:40.00377-08 1 1 00006408 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:11:34.935779-08 0 1 00006460 catalyticact ATP:0000061 two1843 Curated for GO (by WB) LIT-1 phosphorylates POP-1 2025-09-15 09:28:29.626065-07 0 1 00006492 catalyticact ATP:0000061 two1843 Curated for GO (by WB) MOM-4 map kinase kinase activity expressed in HEK293 cells with endogenous human MKK6 as substrate; TAP-1 promotes MOM-4 kinase activity 2024-08-26 07:10:24.617664-07 0 1 00006504 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:44:44.631704-08 0 1 00006514 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 14:10:06.391983-08 0 1 00006534 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, mRNA UTR binding 2018-04-27 13:13:37.748485-07 1 1 00012769 catalyticact ATP:0000061 two1843 Curated for GO (by WB) CKK-1 calcium/calmodulin-dependent protein kinase activity 2024-07-15 07:16:03.736056-07 0 1 00012769 geneprod ATP:0000069 two1843 Curated for GO (by WB) Inter-species PPI, calmodulin binding 2018-04-24 16:45:33.790142-07 1 1 00013111 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Human mTOR protein kinase activity 2024-06-18 13:43:09.56971-07 0 1 00013202 rnai ATP:0000082 two557 Review - no curatable data 2018-03-17 19:09:08.720121-07 1 1 00013295 catalyticact ATP:0000061 two1843 Curated for GO (by WB) rnf-5 ubiquitin protein ligase activity 2025-09-26 08:29:35.954957-07 0 1 00013395 geneprod ATP:0000069 two1843 Curated for GO (by WB), Curated for BioGRID (by WB) PRI 2018-04-24 13:11:14.363035-07 1 1 00013413 catalyticact ATP:0000061 two1843 Curated for GO (by WB) akt-1, akt-2, pdk-1, sgk-1 protein serine/threonine kinase activity 2024-07-15 07:23:02.714632-07 0 1 00013471 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II distal enhancer sequence-specific DNA binding 2018-04-27 13:13:37.759489-07 1 1 00024202 geneprod ATP:0000069 two1843 Curated for GO (by GOA) PRI, RNA binding 2018-04-24 11:10:05.451457-07 1 1 00024211 geneprod ATP:0000069 two1843 Curated for GO (by WB) curation negative, nitric oxide binding 2018-04-27 13:28:01.449702-07 1 1 00024218 catalyticact ATP:0000061 two1843 Curated for GO (by WB) KGB-1 and MEK-1 kinase and VHP-1 phosphatase activities 2024-07-10 11:54:36.724479-07 0 1 00024221 geneprod ATP:0000069 two1843 Curated for GO (by WB) Inter-species PPI, Couldn't annotate the CDF-1 - 14-3-3 interaction because the exact 14-3-3 family can't be determined. kmva 2014-11-21 2019-06-14 15:04:32.909648-07 1 1 00024246 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 13:31:25.884499-08 0 1 00024290 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, DNA binding 2018-04-27 13:28:01.463522-07 1 1 00024291 geneprod ATP:0000069 two1843 Curated for GO (by WB) RRI, mRNA binding 2018-04-27 13:28:01.469798-07 1 1 00024304 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 15:38:05.216912-08 0 1 00024305 catalyticact ATP:0000061 two1843 Curated for GO (by WB) CDC-14 protein phosphatase activity; ZEN-4 plus end-directed microtubule motor activity; human CDK1 cyclin-dependent protein serine/threonine kinase activity 2024-07-15 07:45:29.921492-07 0 1 00024305 geneprod ATP:0000069 two1843 Curated for GO (by WB) microtubule binding,inter-species PPI 2018-04-27 13:28:01.47621-07 1 1 00024334 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 13:02:47.948263-08 0 1 00024367 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-25 10:52:23.339788-07 1 1 00024394 catalyticact ATP:0000061 two1843 Curated for GO (by WB) histone methyltransferase activity (H3-K27-specific) 2021-10-29 18:16:09.503756-07 0 1 00024397 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity 2023-11-06 09:28:28.361005-08 0 1 00024397 geneprod ATP:0000069 two1843 Curated for GO (by GOA) RNA 7-methylguanosine cap binding 2014-09-10 14:15:49.37768-07 1 1 00024418 catalyticact ATP:0000061 two1843 Curated for GO (by WB) This is a somewhat borderline paper. The phosphorylation assays are in vitro, but the protein serine/threonine kinase activity is from whole worm extracts (wild-type and mutant for smg-1. I made an IMP annotation to the GO MF term. 2024-05-14 07:25:02.616836-07 0 1 00024423 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:35:50.576211-08 0 1 00024424 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity 2023-11-06 09:41:26.894909-08 0 1 00024453 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-11-30 11:19:38.14704-08 0 1 00024468 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 14:56:54.402411-08 0 1 00024480 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-03-15 10:01:45.404765-07 0 1 00024497 rnai ATP:0000082 two2987 Large scale RNAi paper (10951 RNAi objects); not in RNAi OA 2013-01-14 14:25:40.064356-08 1 1 00024530 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:58:24.828885-08 0 1 00024570 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ubiquitin-protein transferase activity 2023-11-06 09:53:19.418825-08 0 1 00024579 catalyticact ATP:0000061 two1843 Curated for GO (by WB) metalloendopeptidase activity 2023-11-06 12:27:20.446784-08 0 1 00024595 catalyticact ATP:0000061 two1843 Curated for GO (by WB) UNC-51 protein serine/threonine kinase activity on VAB-8 and UNC-14 2024-07-15 08:03:58.180904-07 0 1 00024605 catalyticact ATP:0000061 two1843 Curated for GO (by WB) AIR-2 phosphorylates BMK-1, ICP-1 and AIR-2 (autophosphorylation) 2024-06-27 09:55:03.138476-07 0 1 00024616 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ATP-dependent diacylglycerol kinase activity 2023-11-06 06:55:41.668731-08 0 1 00024642 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ATP hydrolysis activity 2023-11-06 08:27:42.578266-08 0 1 00024642 geneprod ATP:0000069 two1843 Curated for GO (by GOA) magnesium ion binding 2014-09-11 06:47:27.192601-07 1 1 00024866 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:05:34.317188-08 0 1 00024871 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) N-acetyltransferase activity 2023-11-09 15:04:15.602264-08 0 1 00024886 catalyticact ATP:0000061 two1843 Curated for GO (by WB) AMP-activated protein kinase activity 2022-04-06 13:37:11.310112-07 0 1 00024891 geneprod ATP:0000069 two1843 Curated for GO (by WB) Inter-species PPI, Rap guanyl-nucleotide exchange factor activity 2018-04-30 12:33:48.761865-07 1 1 00024896 geneprod ATP:0000069 two1843 Curated for GO (by WB) peroxisome targeting sequence binding 2014-09-10 08:12:49.461708-07 1 1 00024977 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-27 14:01:09.299625-07 1 1 00025008 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-27 14:01:09.311164-07 1 1 00025019 rnai ATP:0000082 two557 RNAi used to knock down expression of a transgene containing the mce-1 gene.This showed the transgene was expressing mce-1 and showing localization. 2015-03-08 12:31:49.505446-07 1 1 00025054 rnai ATP:0000082 two2987 Large scale RNAi paper (20709 RNAi objects); not in RNAi OA 2013-01-14 14:25:40.133731-08 1 1 00025059 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:04:49.263354-08 0 1 00025063 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:03:52.975802-08 0 1 00025075 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:38:46.64557-08 0 1 00025082 geneprod ATP:0000069 two1843 single-stranded RNA binding 2014-09-16 10:23:38.707915-07 1 1 00025090 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein kinase activity 2022-04-13 13:34:08.011972-07 0 1 00025092 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:56:37.850453-08 0 1 00025104 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 15:13:22.74116-08 0 1 00025130 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Currently curated for C. elegans only 2023-08-25 12:54:22.882873-07 0 1 00025132 catalyticact ATP:0000061 two1843 Curated for GO (by WB) JNK-1 protein kinase activity (GO:0004672) on DAF-16 2024-06-24 07:30:53.988045-07 0 1 00025137 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:33:11.271852-08 0 1 00025147 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-06-10 09:04:12.750351-07 0 1 00025201 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 14:57:36.752447-08 0 1 00025221 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-05-03 15:04:45.332201-07 1 1 00025236 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region DNA binding 2018-04-27 14:01:09.322139-07 1 1 00025248 catalyticact ATP:0000061 two1843 Curated for GO (by WB) UDP-galactopyranose mutase activity 2023-11-06 09:42:57.393981-08 0 1 00026599 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 13:52:00.835732-08 0 1 00026609 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein kinase activity 2022-04-28 05:43:11.871427-07 0 1 00026637 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:08:47.534064-08 0 1 00026734 catalyticact ATP:0000061 two1843 Curated for GO (by WB) calmodulin-dependent protein kinase activity (GO:0004683) 2023-08-14 10:43:07.890178-07 0 1 00026747 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 14:48:51.84932-08 0 1 00026788 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, EMSA 2018-04-27 14:01:09.333248-07 1 1 00026807 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-03-15 10:30:24.739347-07 0 1 00026814 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2022-07-11 07:05:51.120791-07 0 1 00026844 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PDR-1 ubiquitin-protein transferase activity 2025-09-15 10:01:17.286964-07 0 1 00026848 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:45:15.389051-08 0 1 00026859 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2023-11-06 12:52:25.67566-08 0 1 00026859 transporter ATP:0000062 two1843 Curated for GO (by WB) potassium channel regulator activity 2023-11-06 12:52:25.678841-08 0 1 00026863 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:13:44.252527-08 0 1 00026912 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-27 14:09:07.140662-07 1 1 00026928 geneprod ATP:0000069 two1843 Curated for GO (by WB) calcium ion binding 2014-09-11 13:17:31.524003-07 1 1 00026935 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, double-stranded telomeric DNA binding 2018-04-27 14:17:14.631171-07 1 1 00026952 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, DNA binding 2018-04-27 14:17:14.639464-07 1 1 00026975 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-06-30 11:51:06.705484-07 0 1 00026991 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein-disulfide reductase activity 2023-11-06 09:48:45.432599-08 0 1 00027009 geneprod ATP:0000069 two1843 DAF-16 chromatin binding 2014-09-16 10:50:53.36635-07 1 1 00027049 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, DNA binding by EMSA 2018-04-24 14:23:40.310729-07 1 1 00027071 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:35:20.801736-08 0 1 00027071 geneprod ATP:0000069 two1843 Curated for GO (by WB) GTP binding 2014-09-11 06:54:08.951405-07 1 1 00027077 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-09-21 12:02:03.896473-07 0 1 00027082 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-27 14:21:17.233186-07 1 1 00027141 exprmosaic ATP:0000033 two363 2014-10-27 22:24:22.342072-07 1 1 00027189 catalyticact ATP:0000061 two1843 Curated for GO (by WB) aryl sulfotransferase activity 2023-11-06 12:34:48.237709-08 0 1 00027210 geneprod ATP:0000069 two1843 Curated for GO (by WB) Actin filament binding. kmva 2014-11-21 2014-11-21 11:40:00.348443-08 1 1 00027322 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2022-07-11 07:58:07.189412-07 0 1 00027323 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2023-11-06 08:58:50.699812-08 0 1 00027331 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ATP hydrolysis activity 2023-11-06 08:29:12.911373-08 0 1 00027343 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 15:11:53.777038-08 0 1 00027352 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:37:09.962012-08 0 1 00027362 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 15:12:38.485297-08 0 1 00027607 catalyticact ATP:0000061 two1843 Curated for GO (by WB) GSK-3 and MBK-2 protein serine/threonine kinase activity 2024-07-10 11:38:03.188086-07 0 1 00027671 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:34:09.731939-08 0 1 00027679 geneprod ATP:0000069 two1843 Curated for GO (by WB) chitin binding 2014-09-11 07:12:41.885188-07 1 1 00027699 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-03-17 07:08:54.124841-07 0 1 00027747 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 14:01:45.180628-08 0 1 00027754 catalyticact ATP:0000061 two1843 Curated for GO (by WB) IMP evidence for methylmalonyl-CoA mutase activity 2021-09-15 11:53:18.543717-07 0 1 00028315 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-27 14:41:59.658272-07 1 1 00028338 geneprod ATP:0000069 two1843 Curated for GO (by WB) fatty-acyl-CoA binding 2014-09-11 14:10:25.943818-07 1 1 00028359 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:14:22.690219-08 0 1 00028410 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity 2023-11-06 09:55:49.399365-08 0 1 00028488 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 1-hydroxypyrene sulfotransferase activity 2023-11-06 12:36:55.423027-08 0 1 00028741 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 13:28:57.56492-08 0 1 00028756 geneprod ATP:0000069 two1843 Curated for GO (by WB) Protein-cholesterol interaction, mammalian PPI 2018-03-06 13:11:36.772025-08 1 1 00028768 geneprod ATP:0000069 two1843 Curated for GO (by WB) ligand binding, GTP analog binding by GOA-1. 2018-04-30 12:05:22.198414-07 1 1 00028870 geneprod ATP:0000069 two1843 Curated for GO (by WB) histone binding 2014-09-12 06:43:46.655007-07 1 1 00028895 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein kinase activity 2022-04-13 14:12:29.005672-07 0 1 00028908 geneprod ATP:0000069 two1843 Curated for GO (by WB) various phospholipid binding terms 2014-09-02 11:11:42.800651-07 1 1 00028910 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2022-04-13 14:03:15.755443-07 0 1 00028986 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-24 15:33:28.461684-07 1 1 00028994 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:26:18.415703-08 0 1 00029002 geneprod ATP:0000069 two1843 Curated for GO (by WB) Inter-species PPI, BMP binding 2018-04-30 12:11:59.413936-07 1 1 00029039 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:28:27.820227-08 0 1 00029047 catalyticact ATP:0000061 two1843 Curated for GO (by WB) cysteine-type deubiquitinase activity 2023-11-06 12:59:05.465115-08 0 1 00029050 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-03-16 09:25:34.656313-07 0 1 00029051 geneprod ATP:0000069 two1843 Curated for GO (by WB) chromatin binding 2014-09-12 06:49:22.507983-07 1 1 00029117 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, ChIP, sequence-specific DNA binding 2018-04-30 13:34:14.127218-07 1 1 00029127 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-10-14 14:25:30.753666-07 0 1 00029134 catalyticact ATP:0000061 two1843 Curated for GO (by WB) histone H3-tri/di/monomethyl-lysine-4 demethylase activity 2021-08-10 11:59:24.150003-07 0 1 00029147 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-30 13:38:59.859805-07 1 1 00029228 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2017-01-04 11:41:28.081784-08 0 1 00029258 rnai ATP:0000082 two2987 Large scale RNAi paper (3163 RNAi objects); not in RNAi OA 2013-01-14 14:25:40.194995-08 1 1 00029359 otherexpr ATP:0000041 two12028 Chronograms paper 2016-01-12 12:49:13.101359-08 1 1 00029404 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:10:20.668769-08 0 1 00030800 geneprod ATP:0000069 two1843 Curated for GO (by WB) Inter-species PPI, human PPI, calmodulin binding 2018-04-30 13:48:59.541393-07 1 1 00030893 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:42:59.5465-08 0 1 00030933 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Peptide substrate for DKF-2; no in vivo substrate. 2016-07-01 13:47:23.718482-07 0 1 00030935 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 14:59:10.7527-08 0 1 00030943 catalyticact ATP:0000061 two1843 Curated for GO (by WB) JUN kinase activity 2023-11-06 08:15:41.460017-08 0 1 00030960 geneprod ATP:0000069 two1843 Curated for GO (by WB) Inter-species PPI 2018-05-02 17:10:16.365223-07 1 1 00031000 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:46:18.200156-08 0 1 00031005 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:37:22.267121-08 0 1 00031006 otherexpr ATP:0000041 two12028 the patterns are associated to WBPaper00006525 2022-09-15 13:23:20.040214-07 1 1 00031010 geneprod ATP:0000069 two1843 Curated for GO (by WB) Note that this is an inter-species interaction between UNC-50 and S. cerevisiae Arf Gef Gea1p. 2015-07-29 11:10:26.801069-07 1 1 00031084 catalyticact ATP:0000061 two1843 Curated for GO (by WB) CLPP-1, Figure 7B 2018-02-10 17:16:36.367151-08 0 1 00031111 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-25 10:55:13.964792-07 1 1 00031125 catalyticact ATP:0000061 two1843 Curated for GO (by WB) let-767 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 2025-06-06 14:04:53.126154-07 0 1 00031144 geneprod ATP:0000069 two1843 Curated for GO (by WB) steroid hormone binding 2014-09-11 08:27:13.797145-07 1 1 00031342 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2017-02-13 14:00:39.924104-08 0 1 00031380 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-25 10:55:13.976055-07 1 1 00031426 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:17:43.315306-08 0 1 00031434 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2022-04-25 16:12:31.369887-07 0 1 00031471 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, single-stranded RNA binding 2018-04-27 15:24:22.783462-07 1 1 00031511 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 12:18:06.647218-08 0 1 00031524 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PHY-4 peptidyl-proline 4-dioxygenase activity; PDI-2 protein disulfide isomerase activity 2026-03-27 14:02:41.458022-07 0 1 00031545 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) NOT annotations for non-membrane spanning protein tyrosine kinase activity 2024-07-10 11:33:48.660614-07 0 1 00031585 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-05-02 16:32:32.78026-07 1 1 00031592 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:47:27.966715-08 0 1 00031617 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2022-04-08 11:59:28.540694-07 0 1 00031664 catalyticact ATP:0000061 two1843 Curated for GO (by WB) phosphatidylinositol trisphosphate phosphatase activity 2023-11-06 12:48:04.116304-08 0 1 00031692 catalyticact ATP:0000061 two1843 Curated for GO (by WB) IMP evidence for protein serine/threonine kinase activity of PAR-4 2022-08-22 13:09:43.65067-07 0 1 00031703 geneprod ATP:0000069 two1843 Curated for GO (by WB) heme binding 2014-09-11 12:40:40.29559-07 1 1 00031703 transporter ATP:0000062 two1843 Curated for GO (by WB) heme transmembrane transporter activity (GO:0015232) - IDA 2023-08-25 13:37:27.620474-07 0 1 00031861 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 15:00:49.946336-08 0 1 00031897 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 3-beta-hydroxy-delta5-steroid dehydrogenase activity 2023-11-06 08:56:56.08549-08 0 1 00031914 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, RNA binding 2018-04-27 15:32:53.431249-07 1 1 00031956 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 3'-5' DNA helicase activity 2023-11-09 15:09:42.124805-08 0 1 00032019 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2025-03-06 12:54:37.678399-08 0 1 00032021 geneprod ATP:0000069 two1843 Curated for GO (by IntAct) inter-species PPI 2018-05-02 16:07:09.363149-07 1 1 00032033 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 15:16:26.80715-08 0 1 00032034 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin binding 2014-09-11 12:38:48.444767-07 1 1 00032049 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, siRNA binding 2018-04-27 15:36:27.869508-07 1 1 00032072 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:07:59.337643-08 0 1 00032123 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-02-13 13:51:39.131748-08 0 1 00032207 catalyticact ATP:0000061 two1843 Curated for GO (by WB) SAD-1 protein serine/threonine kinase activity 2024-06-04 07:55:30.728546-07 0 1 00032231 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:55:59.735892-08 0 1 00032264 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 13:00:39.323066-08 0 1 00032279 geneprod ATP:0000069 two1843 Curated for GO (by GOA) Ancylostoma hookworms A. caninum DAF-16. kmva 2014-11-24 2018-04-27 15:39:09.167667-07 1 1 00032301 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, RNA binding 2018-04-27 15:41:34.727281-07 1 1 00032328 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-13 14:09:29.765167-08 0 1 00032331 humandisease ATP:0000152 two38202 2018-06-19 16:59:39.058114-07 1 1 00032337 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-03-15 10:03:18.534762-07 0 1 00032366 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-30 17:51:58.271509-08 0 1 00032400 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-27 17:09:15.950475-07 1 1 00032411 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-05-02 10:54:42.409749-07 1 1 00032472 catalyticact ATP:0000061 two1843 Curated for GO (by WB) SUMO conjugating enzyme activity 2021-08-26 14:27:18.100274-07 0 1 00032496 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, mRNA 3'-UTR binding 2018-04-27 17:35:51.618917-07 1 1 00032504 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, siRNA binding 2018-04-24 15:33:28.473944-07 1 1 00032522 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 15:17:21.148972-08 0 1 00032877 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding, PDI 2018-04-24 11:10:05.459425-07 1 1 00032889 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:09:01.844952-08 0 1 00032896 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-24 15:05:12.555317-07 1 1 00032904 catalyticact ATP:0000061 two1843 Curated for GO (by WB) non-membrane spanning protein tyrosine kinase activity 2022-04-08 08:52:18.385864-07 0 1 00032908 catalyticact ATP:0000061 two1843 Curated for GO (by WB) IMP evidence for histone ubiquitin ligase activity 2022-11-04 13:35:55.648239-07 0 1 00032946 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-12-14 13:29:55.142237-08 0 1 00032969 geneprod ATP:0000069 two1843 Curated for GO (by WB) GLB-5 oxygen (O2) binding. kmva 2014-11-24 2014-11-24 08:22:15.073817-08 1 1 00033022 catalyticact ATP:0000061 two1843 Curated for GO (by WB) cysteine-type deubiquitinase activity 2023-11-06 09:40:01.031093-08 0 1 00033024 transporter ATP:0000062 two1843 2025-01-30 17:27:16.405163-08 0 1 00033036 catalyticact ATP:0000061 two1843 Curated for GO (by WB) poly(A) RNA polymerase activity 2023-10-01 16:55:57.755317-07 0 1 00033042 catalyticact ATP:0000061 two1843 Curated for GO (by WB) sulfurtransferase activity 2023-11-06 08:41:09.504399-08 0 1 00033042 geneprod ATP:0000069 two1843 Curated for GO (by WB) yeast result, tRNA binding 2018-04-27 17:15:22.488674-07 1 1 00033044 geneprod ATP:0000069 two1843 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity 2014-09-17 11:15:28.955084-07 1 1 00033073 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2023-11-06 12:54:47.63784-08 0 1 00033073 transporter ATP:0000062 two1843 Curated for GO (by WB) voltage-gated potassium channel activity 2023-11-06 12:54:47.635222-08 0 1 00033091 catalyticact ATP:0000061 two1843 Curated for GO (by WB) sir-2.1 histone h4k deacetylase activity 2025-09-23 08:56:08.830534-07 0 1 00033101 catalyticact ATP:0000061 two1843 Curated for GO (by WB) histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity 2021-08-10 11:57:37.348962-07 0 1 00033104 catalyticact ATP:0000061 two1843 Curated for GO (by WB) peroxidase activity 2023-11-03 13:00:45.44675-07 0 1 00033138 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:06:22.377953-08 0 1 00033201 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 15:07:07.567277-08 0 1 00033201 geneprod ATP:0000069 two1843 Curated for GO (by WB) heme binding 2014-09-12 07:12:41.277843-07 1 1 00033205 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-03-16 09:34:56.320759-07 0 1 00033412 catalyticact ATP:0000061 two1843 Curated for GO (by WB) DNA N-glycosylase activity 2021-05-26 07:43:39.061695-07 0 1 00033449 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region sequence-specific DNA binding 2018-04-27 17:19:55.294664-07 1 1 00033452 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-27 17:21:20.074243-07 1 1 00033462 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2017-02-13 13:50:33.754139-08 0 1 00034639 catalyticact ATP:0000061 two1843 Curated for GO (by WB) S-adenosylmethionine-dependent methyltransferase activity 2023-11-04 13:02:18.648934-07 0 1 00034672 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ATP hydrolysis activity 2023-11-06 09:36:08.156145-08 0 1 00034704 geneprod ATP:0000069 two1843 RNA polymerase II regulatory region sequence-specific DNA binding 2014-09-17 11:20:09.825639-07 1 1 00034714 geneprod ATP:0000069 two1843 sequence-specific DNA binding RNA polymerase II transcription factor activity 2014-09-16 12:10:38.075493-07 1 1 00034727 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-24 15:05:12.563698-07 1 1 00034732 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-27 17:22:38.429439-07 1 1 00034754 geneprod ATP:0000069 two1843 2013-01-27 09:24:27.69464-08 1 1 00034766 geneprod ATP:0000069 two1843 Curated for GO (by WB) protein-lipid interaction, glycolipid binding 2018-04-30 11:57:26.387046-07 1 1 00035082 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:31:35.255835-08 0 1 00035098 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 12:23:29.465739-08 0 1 00035106 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, Y1H 2018-04-27 14:47:45.3194-07 1 1 00035135 geneprod ATP:0000069 two1843 Curated for GO (by WB) calcium ion binding 2014-09-11 10:02:23.453866-07 1 1 00035164 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 15:11:06.65356-08 0 1 00035168 catalyticact ATP:0000061 two1843 Curated for GO (by WB) exonuclease activities 2023-11-04 13:04:21.679749-07 0 1 00035168 geneprod ATP:0000069 two1843 Curated for GO (by WB) RRI, miRNA binding 2018-04-27 17:35:51.626167-07 1 1 00035222 geneprod ATP:0000069 two1843 single-stranded DNA binding 2014-09-18 07:14:31.703403-07 1 1 00035252 geneprod ATP:0000069 two1843 2013-01-27 09:41:02.477789-08 1 1 00035256 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-05-20 08:17:25.866022-07 0 1 00035283 catalyticact ATP:0000061 two1843 Curated for GO (by WB) carbonate dehydratase activity (GO:0004089) 2023-03-17 11:39:05.488974-07 0 1 00035284 humandisease ATP:0000152 two38202 2018-06-18 13:38:55.4629-07 1 1 00035289 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:36:07.636734-08 0 1 00035305 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 12:19:03.009154-08 0 1 00035406 geneprod ATP:0000069 two1843 Curated for GO (by WB) single-stranded RNA binding 2014-09-11 09:39:30.510632-07 1 1 00035407 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein tyrosine kinase activity 2022-04-28 10:14:46.090703-07 0 1 00035411 humandisease ATP:0000152 two38202 2018-06-21 12:46:31.513769-07 1 1 00035427 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-06-12 07:43:30.419634-07 0 1 00035443 catalyticact ATP:0000061 two1843 Curated for GO (by WB) sulfate adenylyltransferase (ADP) activity 2023-11-06 09:01:29.880497-08 0 1 00035467 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI 2018-05-02 10:47:43.574038-07 1 1 00035526 rnai ATP:0000082 two557 All RNAi experiments are in non-elegans. 2014-08-19 17:15:32.37315-07 1 1 00035545 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein kinase activity 2022-07-26 06:18:44.904557-07 0 1 00035548 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:08:18.338348-08 0 1 00035583 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity (GO:0004674) - IDA 2023-08-14 10:48:43.734123-07 0 1 00035594 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2022-04-27 14:01:37.652277-07 0 1 00035902 catalyticact ATP:0000061 two1843 Curated for GO (by WB) IMP evidence for protein serine/threonine kinase activity 2022-04-13 13:30:35.30371-07 0 1 00035929 geneint ATP:0000068 two1760 EMSA physical interaction, need feature object 2014-12-09 12:51:57.553879-08 1 1 00035929 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-05-02 12:06:41.13226-07 1 1 00035985 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:49:48.073457-08 0 1 00036007 geneprod ATP:0000069 two1843 Curated for GO (by WB) lysine-acetylated histone binding 2014-09-11 09:48:53.375903-07 1 1 00036018 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding, protein homodimerization activity 2014-09-11 09:47:16.124935-07 1 1 00036025 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-10-31 13:17:39.820566-07 0 1 00036033 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein-tyrosine sulfotransferase activity 2023-11-06 12:39:13.081506-08 0 1 00036041 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein tyrosine kinase activity 2022-04-07 09:50:05.439275-07 0 1 00036076 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ubiquitin protein ligase activity 2023-11-06 09:37:58.547429-08 0 1 00036106 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-04-24 12:15:55.958206-07 1 1 00036107 geneprod ATP:0000069 two1843 Curated for GO (by WB) mouse PPI, RNA binding 2018-04-24 15:05:12.570745-07 1 1 00036110 catalyticact ATP:0000061 two1843 Curated for GO (by WB) histone demethylase activity 2023-11-06 08:51:00.212761-08 0 1 00036147 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-13 14:06:35.542107-08 0 1 00036149 geneprod ATP:0000069 two1843 Curated for GO (by WB) phosphatidylinositol-4,5-bisphosphate binding, actin filament binding 2014-09-11 09:44:37.253247-07 1 1 00036166 humandisease ATP:0000152 two38202 2018-07-02 13:45:13.183132-07 1 1 00036275 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 15:01:44.034087-08 0 1 00036283 catalyticact ATP:0000061 two1843 Curated for GO (by WB) calmodulin-dependent protein kinase activity 2022-04-27 13:22:01.207724-07 0 1 00036293 humandisease ATP:0000152 two38202 2018-07-02 14:57:47.280042-07 1 1 00036297 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific DNA binding 2018-04-30 11:37:04.656338-07 1 1 00036343 catalyticact ATP:0000061 two1843 Curated for GO (by WB) dopachrome isomerase activity (GO:0004167) 2023-03-17 11:10:37.359524-07 0 1 00036353 geneprod ATP:0000069 two1843 Curated for GO (by WB) microtubule binding 2014-09-02 10:53:57.585928-07 1 1 00036358 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:16:12.070888-08 0 1 00036359 catalyticact ATP:0000061 two1843 Curated for GO (by WB) NOT for RNA helicase activity 2023-11-09 15:06:46.615076-08 0 1 00036359 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, RNA binding 2018-04-27 15:17:42.528595-07 1 1 00036362 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 12:21:08.644573-08 0 1 00036365 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, PDI, sequence-specific DNA binding 2018-04-30 10:57:38.292577-07 1 1 00036376 geneprod ATP:0000069 two1843 2013-01-31 08:53:12.84378-08 1 1 00036391 catalyticact ATP:0000061 two1843 Curated for GO (by WB) histone demethylase activity 2023-11-06 08:52:50.41288-08 0 1 00036391 geneprod ATP:0000069 two1843 Curated for GO (by WB) histone binding 2014-09-12 07:25:42.779473-07 1 1 00036404 geneprod ATP:0000069 two1843 2013-01-31 08:53:12.903825-08 1 1 00036406 geneprod ATP:0000069 two1843 2013-01-31 08:53:12.942572-08 1 1 00036434 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2022-04-08 11:49:40.848753-07 0 1 00036447 geneprod ATP:0000069 two1843 Curated for GO (by WB) actin filament binding 2014-09-02 12:43:17.860895-07 1 1 00036467 rnai ATP:0000082 two557 All RNAi experiments are in briggsae. Not curated for briggsae!! 2014-08-18 17:12:35.548534-07 1 1 00036470 catalyticact ATP:0000061 two1843 Curated for GO (by WB) MPK-1 protein serine/threonine kinase activity (GO:0004674) - IDA - on SKN-1 2024-07-18 10:33:29.645186-07 0 1 00036492 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity 2023-11-06 09:31:46.251992-08 0 1 00036712 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-13 14:10:33.210409-08 0 1 00036740 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PKC-3 protein serine/threonine kinase activity on PAR-3 2024-07-16 07:28:02.489817-07 0 1 00037697 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:59:35.561815-08 0 1 00037788 geneprod ATP:0000069 two1843 Curated for GO (by WB) protein-lipid interaction, phosphatidylinositol binding 2018-04-30 10:17:30.610172-07 1 1 00037805 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:11:11.152772-08 0 1 00037817 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 13:25:21.956115-08 0 1 00037836 geneprod ATP:0000069 two1843 Curated for BioGRID (by WB) human PPI 2019-07-09 15:28:35.83191-07 1 1 00037877 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:40:59.916827-08 0 1 00037900 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Mixed species experiment - C. elegans SRGP-1 GAP and human Rac1 (bacterially expressed CED-10 has no intrinsic GTPase activity) 2025-11-19 11:42:10.121289-08 0 1 00037940 geneprod ATP:0000069 two1843 Curated for GO (by WB) curation negative, chromatin DNA binding 2018-04-30 10:13:00.419309-07 1 1 00037946 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, ChIP-seq, RNA polymerase II regulatory region DNA binding 2018-04-30 10:09:00.950351-07 1 1 00038067 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-05-02 10:40:45.18203-07 1 1 00038083 geneprod ATP:0000069 two1843 Curated for BioGRID (by WB) 2014-05-14 13:49:57.560367-07 1 1 00038108 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) GO:0004090 carbonyl reductase (NADPH) activity 2023-11-06 08:36:28.298417-08 0 1 00038127 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-03-17 07:42:33.426731-07 0 1 00038152 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2017-02-13 13:49:46.54678-08 0 1 00038156 geneprod ATP:0000069 two1843 2013-01-31 09:19:32.473464-08 1 1 00038300 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, double-stranded RNA binding 2018-04-29 22:01:45.555608-07 1 1 00038308 catalyticact ATP:0000061 two1843 Curated for GO (by WB) -xylulose reductase (NADP+) activity 2023-11-06 08:37:58.449318-08 0 1 00038317 catalyticact ATP:0000061 two1843 Curated for GO (by WB) phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2023-11-06 12:50:46.001594-08 0 1 00038317 geneprod ATP:0000069 two1843 Curated for GO (by WB) protein-lipid interaction, phosphatidylinositol binding 2018-04-29 21:53:47.848085-07 1 1 00038328 geneprod ATP:0000069 two1843 Curated for GO (by WB) carbon monoxide sensory activity; nitric oxide binding 2014-09-02 12:39:13.998706-07 1 1 00038332 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region DNA binding 2018-04-29 17:58:52.646223-07 1 1 00038379 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PRMT-1 protein-arginine omega-N asymmetric methyltransferase activity 2024-07-26 13:37:21.14975-07 0 1 00038446 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 13:02:06.58701-08 0 1 00038448 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Mixed species ERK2 protein serine/threonine kinase activity on NOS-3; IMP evidence for MPK-1 phosphorylates NOS-3 2024-07-12 07:09:48.221682-07 0 1 00039781 geneprod ATP:0000069 two1843 Curated for GO (by WB) fatty acid binding 2014-09-12 08:11:33.861818-07 1 1 00039860 geneprod ATP:0000069 two1843 microtubule binding 2014-09-17 11:56:42.838749-07 1 1 00040009 geneprod ATP:0000069 two1843 Curated for GO (by WB) inter-species PPI 2018-04-24 13:22:20.30335-07 1 1 00040066 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-05-02 10:34:28.447179-07 1 1 00040141 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:17:26.433323-08 0 1 00040201 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2022-04-13 13:17:25.719329-07 0 1 00040275 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2022-04-13 13:22:16.91876-07 0 1 00040466 catalyticact ATP:0000061 two1843 SVM Positive, Curation Negative Human enzyme assayed; curated by GOA 2025-11-18 15:19:17.415444-08 0 1 00040537 catalyticact ATP:0000061 two1843 Curated for GO (by WB) cardiolipin synthase (CMP-forming) 2023-10-31 06:59:45.373179-07 0 1 00040583 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-13 14:07:36.431123-08 0 1 00040626 catalyticact ATP:0000061 two1843 Curated for GO (by WB) cystathionine beta-synthase activity 2023-11-06 09:51:22.549459-08 0 1 00040626 geneprod ATP:0000069 two1843 Curated for GO (by WB) pyridoxal phosphate binding 2014-09-11 07:35:11.420292-07 1 1 00040649 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-06 12:44:23.928782-08 0 1 00040730 geneprod ATP:0000069 two1843 Curated for GO (by WB) heme binding 2014-09-12 08:14:17.500177-07 1 1 00040739 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-04-08 09:32:36.515121-07 0 1 00040760 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2017-02-13 13:59:56.125097-08 0 1 00040823 antibody ATP:0000096 two1760 2014-11-21 09:19:33.11686-08 1 1 00040826 catalyticact ATP:0000061 two1843 Curated for GO (by WB) DNA endonuclease activity 2023-11-03 13:02:08.391605-07 0 1 00040839 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) svh-2 transmembrane receptor protein tyrosine kinase activity 2025-11-18 15:14:31.214777-08 0 1 00040869 rnai ATP:0000082 two557 methods paper - no curatable data, but positive for RNAi experiments 2018-03-17 19:07:21.09954-07 1 1 00040918 geneprod ATP:0000069 two1843 Curated for GO (by WB) human PPI 2018-05-01 17:18:25.54991-07 1 1 00040926 rnai ATP:0000082 two557 methods paper - no curatable data, but positive for RNAi experiments 2018-03-17 19:07:21.111063-07 1 1 00040950 geneprod ATP:0000069 two1843 Curated for GO (by WB) cholesterol binding 2014-09-11 07:36:56.06862-07 1 1 00040978 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) steroid dehydrogenase activity 2023-11-06 07:00:21.053281-08 0 1 00041030 rnai ATP:0000082 two557 methods paper - no curatable data, but positive for RNAi experiments 2018-03-17 19:07:21.115541-07 1 1 00041049 rnai ATP:0000082 two557 methods paper - no curatable data, but positive for RNAi experiments 2018-03-17 19:07:21.119936-07 1 1 00041203 catalyticact ATP:0000061 two1843 Curated for GO (by WB) monomeric actin binding and effects on actin polymerization (this is a borderline paper with physical interactions) but for now will keep as positive for catalytic activity. 2026-05-05 13:41:59.821204-07 0 1 00041233 catalyticact ATP:0000061 two1843 Curated for GO (by WB) IMP for two enzymatic activities of COQ-3 2025-09-03 12:48:20.869483-07 0 1 00041279 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein kinase activity 2022-04-13 14:14:38.641854-07 0 1 00041282 catalyticact ATP:0000061 two1843 Curated for GO (by WB) cysteine-type endopeptidase activity 2023-11-07 06:12:38.11256-08 0 1 00041301 rnai ATP:0000082 two557 Although this contains an RNAi experiment, it is to show that the effects of small molecules (named A!, B1 etc) are dependent on certain genes...basically not really curatable 2015-10-18 19:30:38.866925-07 1 1 00041321 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 14:27:53.15282-08 0 1 00041347 catalyticact ATP:0000061 two1843 Curated for GO by CACAO. 2016-11-30 15:03:12.503475-08 0 1 00041348 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-05-01 17:13:49.171519-07 1 1 00041372 catalyticact ATP:0000061 two1843 Curated for GO (by WB) IMP evidence for mboa-7 lysophospholipid acyltransferase activity 2025-07-30 08:56:00.832584-07 0 1 00041378 catalyticact ATP:0000061 two1843 Curated for GO (by WB) gna-1 glucosamine 6-phosphate N-acetyltransferase activity 2025-07-30 08:39:07.833458-07 0 1 00041416 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-11-30 14:08:53.709599-08 0 1 00041416 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI 2018-05-01 17:11:20.830988-07 1 1 00041419 otherexpr ATP:0000041 two12028 This is the transgeneome paper, data goes in through Cite Minus, therefore it would alway come up as not curated in postgres. Will flag as validated negative to make it disappear from the list. 2018-06-30 13:35:18.969108-07 1 1 00041475 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-05-02 12:38:50.831897-07 0 1 00041482 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) slx-1 endonuclease activity 2025-05-02 06:59:54.138636-07 0 1 00041503 catalyticact ATP:0000061 two1843 Curated for GO (by WB) endopeptidase activity 2023-11-03 13:06:37.357207-07 0 1 00041519 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:20:30.999475-08 0 1 00041578 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ipla-1 calcium-independent phospholipase A2 activity 2025-04-30 11:33:16.322075-07 0 1 00041610 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-04-13 02:04:02.574498-07 0 1 00041646 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) protein kinase activities 2023-11-08 07:55:10.098861-08 0 1 00041734 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 15:09:34.631524-08 0 1 00041771 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, double-stranded RNA binding 2018-04-26 16:45:19.0065-07 1 1 00041799 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, transcription regulatory region DNA binding 2018-04-26 16:27:43.526851-07 1 1 00041802 catalyticact ATP:0000061 two1843 Curated for GO (by WB) mps-1 protein serine/threonine kinase activity; acp-2 protein serine/threonine phosphatase activity; both on shw-3 (kht-1 in the paper) 2024-09-05 12:29:36.572147-07 0 1 00041851 genereg ATP:0000070 two557 2013-12-09 14:10:53.707619-08 1 1 00041886 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity 2023-11-06 09:30:12.197603-08 0 1 00041886 geneprod ATP:0000069 two1843 Curated for GO (by GOA) RNA 7-methylguanosine cap binding 2014-09-11 09:25:14.974019-07 1 1 00041946 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 13:16:38.836035-08 0 1 00041960 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) protein kinase activity 2023-11-06 07:28:54.336767-08 0 1 00041976 catalyticact ATP:0000061 two1843 Curated for GO (by WB) wts-1 IMP evidence for protein serine/threonine kinase activity 2024-06-05 10:36:35.186078-07 0 1 00042055 catalyticact ATP:0000061 two1843 Curated for GO (by WB) DNPP-1 metaolloaminopeptidase activity 2024-06-04 11:25:49.773668-07 0 1 00042062 catalyticact ATP:0000061 two1843 Curated for GO (by WB) cyclin-dependent protein serine/threonine kinase activity (GO:0004693); protein serine/threonine kinase activity (GO:0004674); protein kinase activity (GO:0004672) 2023-07-31 06:55:18.853232-07 0 1 00042067 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2023-11-06 07:30:27.954801-08 0 1 00042074 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) 2024-04-25 12:03:06.913402-07 0 1 00042106 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2024-04-25 11:53:52.261625-07 0 1 00042127 transporter ATP:0000062 two1843 2025-01-31 13:20:11.644038-08 0 1 00042132 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI 2018-04-24 12:28:38.695493-07 1 1 00042209 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ubiquitin-protein transferase activity 2023-09-25 07:22:46.111882-07 0 1 00042218 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) mannosyltransferase activity 2023-09-25 06:36:34.134256-07 0 1 00042232 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ubiquitin protein ligase activity | ubiquitin conjugating enzyme activity 2023-09-22 08:35:20.841823-07 0 1 00042271 catalyticact ATP:0000061 two1843 Curated for GO (by WB) glutathione-disulfide reductase (NADP) activity 2023-09-21 12:59:24.22844-07 0 1 00042295 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, RNA polymerase II regulatory region DNA binding 2018-04-25 15:50:34.51883-07 1 1 00042476 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) fucosyltransferase activity and children 2023-09-19 07:07:33.135804-07 0 1 00042545 catalyticact ATP:0000061 two1843 Curated for GO (by WB) UNC-43 - calmodulin-dependent protein kinase activity; TAX-6 - calmodulin-dependent protein phosphatase activity 2024-06-14 08:54:06.677137-07 0 1 00042585 catalyticact ATP:0000061 two1843 Curated for GO (by WB) NOT annotation for ppk-2 to 1-phosphatidylinositol-5-phosphate 4-kinase activity 2023-09-18 07:23:46.961041-07 0 1 00042586 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) protein serine/threonine phosphatase activity 2023-09-18 07:12:42.549499-07 0 1 00042588 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) cysteine-type deubiquitinase activity 2023-09-18 06:48:59.609923-07 0 1 00043905 rnai ATP:0000082 two557 All RNAi experiments are in non elegans 2014-08-19 17:57:15.530444-07 1 1 00043906 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, ChIP-seq 2018-05-01 14:35:06.819311-07 1 1 00043915 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2023-09-15 11:54:46.69774-07 0 1 00043926 catalyticact ATP:0000061 two1843 Curated for GO (by WB) thymidine kinase activity 2023-09-15 11:40:15.69157-07 0 1 00043942 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ribosyltransferase and synthase activities 2023-11-06 08:34:23.995285-08 0 1 00043972 transporter ATP:0000062 two1843 Curated for GO (by WB) voltage-gated calcium channel activity 2023-09-15 10:29:33.749531-07 0 1 00044007 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein-arginine omega-N symmetric methyltransferase activity | histone H4R3 methyltransferase activity 2023-09-14 17:15:53.945298-07 0 1 00044012 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Curated ppfr-1 to protein phosphatase activator activity with IMP evidence code. This paper was slightly borderline, but since I was able to make an annotation, I'm considering it a positive. 2023-09-14 16:56:44.46283-07 0 1 00044052 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-10-12 10:50:38.716671-07 0 1 00044102 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ATP hydrolysis activity 2023-09-14 12:31:04.143236-07 0 1 00044147 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI 2018-05-01 14:31:42.48224-07 1 1 00044189 exprmosaic ATP:0000033 two363 2014-07-24 16:37:56.921579-07 1 1 00044277 catalyticact ATP:0000061 two1843 Curated for GO (by WB) cysteine synthase activity | L-3-cyanoalanine synthase activity 2023-09-14 09:08:52.818591-07 0 1 00044317 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity 2023-09-14 07:52:47.25686-07 0 1 00044350 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein-arginine N-methyltransferase activity 2023-09-13 09:39:31.138687-07 0 1 00044427 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Consistent with this, our examination revealed LDH activity 3- fold higher in lbp-5(tm1618) mutants than in N2 worms (Fig. 1D). 2023-09-13 09:25:37.952245-07 0 1 00044443 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 15:38:49.34641-08 0 1 00044468 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-02-13 13:53:28.242947-08 0 1 00044498 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI, RDE-4 dsRNA binding 2018-04-26 16:19:27.000758-07 1 1 00044602 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) cysteine-type deubiquitinase activity 2022-04-07 10:42:27.497418-07 0 1 00044622 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-05-01 14:17:54.529641-07 1 1 00044726 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ATP hydrolysis activity 2023-11-09 15:08:14.184226-08 0 1 00044759 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 5'-3' exoribonuclease activity 2022-03-30 12:12:58.352894-07 0 1 00044808 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein kinase activity 2022-03-07 08:04:55.765255-08 0 1 00044960 catalyticact ATP:0000061 two1843 Curated for GO (by IntAct) IMP evidence for ubiquitination, but annotations made to the complex as a whole. Not sure if this is the correct way to annotate these experiments. 2021-10-29 07:39:39.32637-07 0 1 00044989 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ubiquitin-protein transferase activity 2021-10-29 07:27:09.159352-07 0 1 00045044 catalyticact ATP:0000061 two1843 Curated for GO (by WB) IMP for serine-type endopeptidase activity 2023-11-03 13:11:44.648995-07 0 1 00045091 catalyticact ATP:0000061 two1843 Curated for GO (by WB) RNA-directed RNA polymerase activity 2021-09-08 13:31:35.046532-07 0 1 00045092 catalyticact ATP:0000061 two1843 Curated for GO (by WB) histone methyltransferase activity and histone demethylase activity 2021-09-08 09:53:15.037803-07 0 1 00045105 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:47:09.245724-08 0 1 00045183 catalyticact ATP:0000061 two1843 Curated for GO (by WB) endoribonuclease activity, cleaving siRNA-paired mRNA 2021-08-30 09:20:59.03282-07 0 1 00045248 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ubiquitin conjugating enzyme activity 2021-08-30 09:01:58.984548-07 0 1 00045264 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2017-02-13 13:55:21.760716-08 0 1 00045320 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, Y1H and gel shift assays 2018-04-26 16:18:15.143531-07 1 1 00045350 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI 2018-04-24 14:55:51.51017-07 1 1 00045489 catalyticact ATP:0000061 two1843 Curated for GO (by IntAct) Annotations were made to a ComplexPortal id and not to individual gene products. glycogen (starch) synthase activity and glycosyltransferase activity 2021-08-20 07:59:44.081596-07 0 1 00045499 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-07-28 15:05:43.764787-07 0 1 00045518 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-07-14 09:31:43.009394-07 0 1 00045536 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ATP hydrolysis activity 2021-08-16 13:18:22.238042-07 0 1 00045661 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) phosphatidylinositol-3-phosphate phosphatase activity 2023-11-06 12:46:42.208454-08 0 1 00045692 catalyticact ATP:0000061 two1843 Curated for GO (by WB) human SUMO conjugating enzyme activity (IDA) 2021-08-16 12:00:40.620852-07 0 1 00045720 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 13:40:13.682173-08 0 1 00045849 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) IMP for UDP-N-acetylglucosamine 4-epimerase activity and UDP-glucose 4-epimerase activity 2021-08-09 07:37:09.843717-07 0 1 00045868 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 14:56:27.377428-08 0 1 00045909 catalyticact ATP:0000061 two1843 Curated for GO (by WB) DNA-(apurinic or apyrimidinic site) endonuclease activity 2021-07-30 07:51:57.502219-07 0 1 00045971 catalyticact ATP:0000061 two1843 Curated for GO (by WB) RNA ligase (ATP) activity 2021-07-28 13:48:15.799722-07 0 1 00045987 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protease activity 2021-06-11 12:50:24.895356-07 0 1 00046049 catalyticact ATP:0000061 two1843 Curated for GO (by WB) N-acylphosphatidylethanolamine-specific phospholipase D activity 2021-07-28 07:51:51.566506-07 0 1 00046051 catalyticact ATP:0000061 two1843 Curated for GO (by WB) RNA ligase 2023-11-07 06:16:33.107805-08 0 1 00046087 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2021-07-28 07:47:36.964775-07 0 1 00046097 catalyticact ATP:0000061 two1843 Curated for GO (by WB) histone-arginine N-methyltransferase activity 2021-07-26 09:36:20.484746-07 0 1 00046113 catalyticact ATP:0000061 two1843 Curated for GO (by WB) beta-N-acetylgalactosaminidase activity There may be more here, but would have to examine the assays in greater detail. 2021-07-23 08:05:38.770235-07 0 1 00046118 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Note that this resulted in an IMP annotation for mpk-1; the in vitro experiments were performed with murine ERK. 2015-04-16 13:09:06.027989-07 0 1 00046207 catalyticact ATP:0000061 two1843 Curated for GO (by WB) LIT-1 and MOM-4 protein serine/threonine kinase activity with substrates 2024-06-27 09:14:41.593867-07 0 1 00046221 catalyticact ATP:0000061 two1843 Curated for GO (by WB) GTPase activator activity 2021-07-20 06:56:04.622076-07 0 1 00046296 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-02-05 10:24:43.234758-08 0 1 00046365 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI, sequence-specific 2018-04-26 13:13:02.214096-07 1 1 00046369 transporter ATP:0000062 two1843 Curated for GO (by WB) 2025-01-31 14:46:03.994613-08 0 1 00046393 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-02-10 13:13:40.706828-08 0 1 00046398 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) Transcription elongation assays. GOA made a BP annotation; not sure if there's an appropriate MF annotation. 2015-02-10 10:37:19.694326-08 0 1 00046398 geneprod ATP:0000069 two1843 Curated for GO (by GOA) Inter-species PPI 2018-04-26 13:09:28.410067-07 1 1 00046405 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) Contacted GOA to update evidence code to experimental code. 2015-02-09 12:46:41.046353-08 0 1 00046409 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) 2015-02-09 10:27:39.301509-08 0 1 00046489 geneprod ATP:0000069 two1843 Curated for GO (by WB) UNC-87 actin and myosin binding annotations using IDA evidence code. Can't use IPI because the specific gene product isn't known, i.e. which myosin or which actin. 2015-04-03 11:34:09.482216-07 1 1 00046502 catalyticact ATP:0000061 two1843 Curated for GO (by WB) histone-arginine N-methyltransferase activity 2021-07-19 07:54:40.662271-07 0 1 00046515 transporter ATP:0000062 two1843 Curated for GO (by WB) ammonia transporter 2021-11-22 17:56:21.779027-08 0 1 00046543 catalyticact ATP:0000061 two1843 Curated for GO (by WB) DNA-(apurinic or apyrimidinic site) endonuclease activity 2021-07-19 07:37:42.255918-07 0 1 00046571 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Protein serine/threonine kinase activity. 2021-07-16 07:57:24.028904-07 0 1 00046571 geneint ATP:0000068 two38423 2017-11-15 10:41:43.173683-08 1 1 00046572 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-10-16 11:41:10.953387-07 0 1 00046585 catalyticact ATP:0000061 two1843 Curated for GO (by WB) IMP evidence for metabolic enzymes. 2021-07-15 07:33:35.138759-07 0 1 00046636 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) Protein kinase activity. 2021-07-13 10:53:34.917491-07 0 1 00046700 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Metalloaminopeptidase activity 2021-07-13 09:54:00.866567-07 0 1 00046705 catalyticact ATP:0000061 two1843 Whole animal extracts with wt and mutant proteins. 2016-07-05 09:14:15.409229-07 0 1 00046716 exprmosaic ATP:0000033 two363 2015-05-15 11:23:32.872584-07 1 1 00046746 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) 2017-02-13 13:53:32.309159-08 0 1 00046816 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Histone methyltransferase activity. 2021-07-13 09:02:07.201955-07 0 1 00046888 catalyticact ATP:0000061 two1843 Curated for GO (by WB) m7G(5')pppN diphosphatase activity (human, elegans, Ascaris) 2021-07-08 16:18:26.620736-07 0 1 00046915 catalyticact ATP:0000061 two1843 Curated for GO (by WB) GO:0005006 epidermal growth factor receptor activity - IDA Curated in GO-CAM: http://noctua.geneontology.org/editor/graph/gomodel:56d1143000000176 2023-10-13 11:59:29.25027-07 0 1 00046940 geneint ATP:0000068 two1760 2017-11-15 10:51:21.193188-08 1 1 00046955 geneprod ATP:0000069 two1843 Curated for GO (by WB) PRI 2018-04-25 17:02:44.485125-07 1 1 00046973 catalyticact ATP:0000061 two1843 Curated for GO (by WB) UNC-43 calmodulin-dependent protein kinase activity on DRP-1 2024-06-18 14:09:01.611712-07 0 1 00046974 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Poly(A) polymerase activity of GLD-2. GLD-3 regulatory function. 2021-07-07 13:41:15.595228-07 0 1 00046983 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PLK-1 protein serine/threonine kinase activity on KNL-1 2024-07-26 07:44:30.749851-07 0 1 00047043 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2015-11-13 13:28:05.250233-08 0 1 00047065 catalyticact ATP:0000061 two1843 Curated for GO (by WB) AIR-1 and AIR-2 protein serine/threonine kinase activity on KLP-7 2024-07-26 07:36:49.553243-07 0 1 00047095 catalyticact ATP:0000061 two1843 Curated for GO (by WB) DNase II activity of NUC-1 2021-07-07 12:13:56.262387-07 0 1 00048387 geneprod ATP:0000069 two1843 Curated for GO (by WB) PDI 2018-04-25 17:02:44.507313-07 1 1 00048424 catalyticact ATP:0000061 two1843 Curated for GO (by WB) DNase II activities 2021-07-07 10:40:19.933039-07 0 1 00048425 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-04-29 11:48:06.883788-07 0 1 00048594 catalyticact ATP:0000061 two1843 Curated for GO (by WB) An IMP annotation to the BP term for ULP-2. 2015-10-15 13:00:29.312442-07 0 1 00048677 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-04-29 11:31:15.845164-07 0 1 00048710 catalyticact ATP:0000061 two1843 Curated for GO (by WB) GEF activity for RAB-11.1 (technically an enzyme regulator activity) 2021-07-01 08:29:37.47624-07 0 1 00048791 catalyticact ATP:0000061 two1843 Human enzyme methylating human and C. elegans proteins. 2016-11-08 09:07:07.298515-08 0 1 00048842 catalyticact ATP:0000061 two1843 Curated for GO (by WB) GAP activity and GTPase activity 2021-06-30 07:35:30.91263-07 0 1 00048975 catalyticact ATP:0000061 two1843 Curated for GO (by WB) GTPase activity; G protein activity, GEF activity 2021-06-28 07:42:47.347118-07 0 1 00048992 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity 2021-08-17 10:12:50.095928-07 0 1 00049116 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PI3 kinase assays with VPS-34 and also with human proteins. 2021-06-23 11:02:20.379393-07 0 1 00049330 transporter ATP:0000062 two1843 Curated for GO (by WB) MEC-4 sodium channel activity. 2021-06-22 08:19:50.262955-07 0 1 00049350 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) serine-type endopeptidase activity 2023-11-03 13:10:19.793683-07 0 1 00049423 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-05-06 10:39:08.393202-07 0 1 00049591 catalyticact ATP:0000061 two1843 Curated for GO (by WB) glutathione-disulfide reductase (NADPH) activity 2021-06-18 07:51:15.596146-07 0 1 00049683 catalyticact ATP:0000061 two1843 Curated for GO (by WB) alanine-glyoxylate transaminase activity 2021-06-17 13:54:27.440291-07 0 1 00049842 catalyticact ATP:0000061 two1843 Curated for GO (by WB) double-stranded DNA endodeoxyribonuclease activity 2021-06-15 09:22:50.201952-07 0 1 00050075 rnai ATP:0000082 two2987 Methods paper 2019-04-17 08:04:34.166819-07 1 1 00050159 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) chondroitin 4-sulfotransferase activity 2021-06-14 08:44:53.477751-07 0 1 00050178 catalyticact ATP:0000061 two1843 Curated for GO (by WB) DKF-2 protein serine/threonine kinase activity on PIFK-1 2024-07-25 10:16:18.968979-07 0 1 00050185 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ubiquitin-ubiquitin ligase activity 2021-06-14 08:12:08.258849-07 0 1 00050212 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PAR-1 and PKC-3 protein serine/threonine kinase activity on LIN-5 2024-07-12 06:58:36.587373-07 0 1 00050258 catalyticact ATP:0000061 two1843 Curated for GO (by WB) 2016-12-08 13:48:43.545357-08 0 1 00050394 transporter ATP:0000062 two1843 Curated for GO (by WB) voltage-gated chloride channel activity 2021-06-14 07:51:18.599832-07 0 1 00050413 catalyticact ATP:0000061 two1843 Curated for GO (by WB) AKT-1 protein serine/threonine kinase activity OSM-9 target 2024-06-24 06:56:35.713712-07 0 1 00050470 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Curated for BP terms for lin-23. 2017-01-26 10:37:30.592402-08 0 1 00050783 transporter ATP:0000062 two1843 Curated for GO (by GOA) calcium:sodium antiporter activity 2021-06-03 10:09:16.492723-07 0 1 00051469 catalyticact ATP:0000061 two1843 Curated for GO (by WB) adenyl-nucleotide exchange factor activity 2021-06-03 09:04:37.925203-07 0 1 00051513 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine kinase activity 2021-06-03 08:48:41.592591-07 0 1 00052935 catalyticact ATP:0000061 two1843 Curated for GO (by WB) GEF activity 2021-06-03 08:32:11.314926-07 0 1 00053233 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PLK-1 serine/threonine protein kinase activity on NPP-1, NPP-4, and NPP-11 2024-06-25 09:00:08.609685-07 0 1 00053597 catalyticact ATP:0000061 two1843 Curated for GO (by WB) methyltransferase activity 2021-05-28 08:21:58.142244-07 0 1 00053631 catalyticact ATP:0000061 two1843 Curated for GO (by WB) epidermal growth factor receptor activity 2021-11-01 14:02:51.054257-07 0 1 00053669 catalyticact ATP:0000061 two1843 Curated for GO (by WB) AAK-2 AMP-activated protein kinase activity; ATIC-1 phosphoribosylaminoimidazolecarboxamide formyltransferase activity AND IMP cyclohydrolase activity 2024-07-17 08:50:39.041068-07 0 1 00053790 catalyticact ATP:0000061 two1843 Curated for GO (by WB) histone methyltransferase activity (H3-K36 specific) 2021-05-28 07:24:58.59515-07 0 1 00053836 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) Phosphatase activity. 2021-05-28 06:40:59.575628-07 0 1 00053882 transporter ATP:0000062 two1843 Curated for GO (by WB) IMP evidence for vitamin b12 transporter activity 2021-08-30 10:11:53.857655-07 0 1 00053896 catalyticact ATP:0000061 two1843 Curated for GO (by WB) IMP and IGI evidence for histone demethylase activity. 2021-05-27 13:36:50.530143-07 0 1 00054648 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) acyl-CoA oxidase activity; medium-chain fatty acid-CoA ligase activity 2025-11-05 10:58:14.086594-08 0 1 00054685 transporter ATP:0000062 two1843 Curated for GO (by GOA) 2025-01-31 15:33:22.186267-08 0 1 00054882 newmutant ATP:0000083 two2987 2019-03-03 18:03:39.37719-08 1 1 00056082 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein-arginine omega-N asymmetric methyltransferase activity 2021-05-25 06:31:19.813823-07 0 1 00056110 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ATPase, acting on DNA 2021-05-24 11:33:02.560412-07 0 1 00057135 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) protein tyrosine kinase activity 2021-05-24 08:47:05.176161-07 0 1 00058886 catalyticact ATP:0000061 two1843 Curated for GO (by WB) metalloaminopeptidase activity 2022-02-17 12:38:53.414803-08 0 1 00059048 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) protein serine/threonine kinase activity 2021-10-15 07:27:00.789779-07 0 1 00059645 catalyticact ATP:0000061 two1843 Curated for GO (by WB) MBK-2 protein serine/threonine kinase activity on MEI-1 katanin ATPase activity (shown separately) 2024-07-25 09:54:08.357622-07 0 1 00059765 catalyticact ATP:0000061 two1843 2022-02-03 11:24:39.941341-08 0 1 00059848 catalyticact ATP:0000061 two1843 Curated for GO (by WB) src-1 protein tyrosine kinase and ptp-3 protein phosphatase activities. 2024-07-29 07:11:32.012225-07 0 1 00060273 catalyticact ATP:0000061 two1843 Curated for GO (by WB) VRK-1 protein serine/threonine kinase activity on AAK-2 2024-06-25 12:33:25.526445-07 0 1 00060400 geneprod ATP:0000069 two38423 2020-10-05 12:01:13.571645-07 1 1 00060538 transporter ATP:0000062 two1843 Curated for GO (by WB) temperature-gated cation channel activity 2021-07-30 08:28:42.597223-07 0 1 00060555 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PLK-1 protein serine/threonine kinase activity on LMN-1 2024-06-18 14:05:56.503709-07 0 1 00060669 genereg ATP:0000070 two38423 2020-12-14 18:17:58.149011-08 1 1 00060704 genereg ATP:0000070 two38423 2020-12-14 18:45:16.453455-08 1 1 00060733 genereg ATP:0000070 two38423 2020-12-14 17:06:43.090531-08 1 1 00060736 genereg ATP:0000070 two38423 2020-12-09 14:13:38.132791-08 1 1 00060737 genereg ATP:0000070 two38423 2020-12-09 14:13:38.138861-08 1 1 00060738 genereg ATP:0000070 two38423 2020-12-09 14:13:38.14421-08 1 1 00060751 genereg ATP:0000070 two38423 2020-12-14 17:06:43.136474-08 1 1 00060754 genereg ATP:0000070 two38423 2020-12-14 13:29:50.61896-08 1 1 00060760 genereg ATP:0000070 two38423 2020-12-14 12:51:01.595732-08 1 1 00060771 genereg ATP:0000070 two38423 2020-12-15 14:08:09.664649-08 1 1 00060773 genereg ATP:0000070 two38423 2020-12-15 14:08:09.66715-08 1 1 00060774 genereg ATP:0000070 two38423 2020-12-15 12:37:16.636308-08 1 1 00060799 humandisease ATP:0000152 two324 Toxicology 2023-07-13 12:00:26.827867-07 1 1 00060977 catalyticact ATP:0000061 two1843 Curated for GO (by WB) deubiquitinase activity; NEDD8-specific protease activity 2021-06-28 08:43:24.583725-07 0 1 00061062 catalyticact ATP:0000061 two1843 Curated for GO (by WB) BRC-1 ubiquitin protein ligase activity on DGK-3; also commercial PKA protein kinase activity on BRC-1 2024-07-16 08:00:27.761546-07 0 1 00061339 catalyticact ATP:0000061 two1843 Curated for GO (by WB) chitinase activity 2021-06-25 09:27:02.093484-07 0 1 00061388 catalyticact ATP:0000061 two1843 Curated for GO (by WB) non-membrane spanning protein tyrosine kinase activity (GO:0004715) - IDA Kinase assay used human SRC and C. elegans EPHX-1 as a substrate. 2023-08-09 07:25:33.570101-07 0 1 00061567 catalyticact ATP:0000061 two1843 Curated for GO (by WB) NAD+ hydrolase activity 2021-07-26 09:01:59.117105-07 0 1 00061885 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) tubulin-glutamic acid ligase activity 2021-10-20 10:42:13.732415-07 0 1 00061912 catalyticact ATP:0000061 two1843 Annotated unc-45 to protein folding chaperone, but enzymatic activity was for a rabbit myosin used in the assay. | Protection of myosin enzymatic activity from heat by UNC-45B proteins was essentially done as previously described.21 Briefly, 0.4 μM of S1 Fragment (Rabbit Skeletal Muscle, Cytoskeleton #CS-MYS04) was incubated either alone or with 2 μM UNC-45B 2023-09-11 09:41:05.529992-07 0 1 00062004 catalyticact ATP:0000061 two1843 Curated for GO (by GOA) 2022-01-28 13:34:17.56094-08 0 1 00062085 catalyticact ATP:0000061 two1843 Curated for GO (by WB) CDK1 human - cyclin-dependent protein serine/threonine kinase activity; cdk-1 ISS evidence 2024-06-13 08:41:51.686921-07 0 1 00062085 geneprod ATP:0000069 two38423 2021-11-08 15:40:49.320336-08 1 1 00062147 antibody ATP:0000096 two38423 2021-11-23 14:19:10.762976-08 1 1 00062529 otherexpr ATP:0000041 two12028 Curated companion paper WBPaper00062293 2023-06-05 12:34:07.484539-07 1 1 00062616 transporter ATP:0000062 two1843 Curated for GO (by WB) DAT-1 dopamine:sodium symporter activity 2026-04-17 11:47:03.885987-07 0 1 00062649 catalyticact ATP:0000061 two1843 Curated for GO (by WB) methanethiol oxidase activity 2022-06-09 17:51:11.081698-07 0 1 00064064 catalyticact ATP:0000061 two1843 Curated for GO (by WB) let-363 protein serine/threonine kinase activity 2024-06-12 06:45:46.571891-07 0 1 00064160 catalyticact ATP:0000061 two1843 Curated for GO (by WB) IMP evidence for hasp-1 H3T3 in vivo phosphorylation 2024-06-11 08:21:39.09909-07 0 1 00064360 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity (GO:0004674) - IDA 2023-07-17 07:22:43.344283-07 0 1 00064616 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity; protein histidine kinase activity 2023-08-03 11:09:27.370496-07 0 1 00064771 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Recombinant mouse PKA (NEB) phosphorylates ALG-1; made an annotation to the mouse protein and then transferred, with extension, to C. elegans kin-1 2024-06-07 07:44:35.283522-07 0 1 00064972 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein farnesyltransferase activity 2023-03-28 16:11:20.810914-07 0 1 00064989 catalyticact ATP:0000061 two1843 Curated for GO (by WB) monooxygenase activity has_input (L-tryptophan) 2023-03-28 15:41:04.005828-07 0 1 00065028 geneprod ATP:0000069 two38423 2023-03-27 15:36:32.137097-07 1 1 00065033 geneprod ATP:0000069 two38423 2023-03-27 14:35:01.311645-07 1 1 00065045 catalyticact ATP:0000061 two1843 Curated for GO (by WB) mrck-1 myosin light chain kinase activity 2024-06-07 07:22:32.447938-07 0 1 00065045 geneprod ATP:0000069 two38423 2023-03-06 13:53:07.532366-08 1 1 00065170 geneprod ATP:0000069 two38423 2023-04-03 17:58:09.403303-07 1 1 00065175 geneprod ATP:0000069 two38423 2023-04-05 14:30:09.867947-07 1 1 00065284 geneprod ATP:0000069 two38423 2023-04-19 11:58:27.049958-07 1 1 00065285 catalyticact ATP:0000061 two1843 Curated for GO (by WB) plk-1 protein serine/threonine kinase activity 2024-06-06 07:29:27.481591-07 0 1 00065285 geneprod ATP:0000069 two38423 2024-02-16 16:56:21.337813-08 1 1 00065314 geneprod ATP:0000069 two38423 2023-05-03 15:53:59.933444-07 1 1 00065351 geneprod ATP:0000069 two38423 2023-05-12 13:37:35.739297-07 1 1 00065590 geneprod ATP:0000069 two38423 2023-07-06 13:38:09.274736-07 1 1 00065603 geneprod ATP:0000069 two38423 2023-07-10 13:49:38.325008-07 1 1 00065609 catalyticact ATP:0000061 two1843 Curated for GO (by WB) unc-43 calcium/calmodulin-dependent protein kinase activity 2024-07-16 07:44:53.974009-07 0 1 00065609 geneprod ATP:0000069 two38423 2024-02-16 16:39:43.438593-08 1 1 00065634 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein-lysine N-methyltransferase activity 2023-11-01 08:23:05.010274-07 0 1 00065640 geneprod ATP:0000069 two38423 2024-02-16 16:39:43.444202-08 1 1 00065647 geneprod ATP:0000069 two38423 2023-07-10 13:21:23.23365-07 1 1 00065650 geneprod ATP:0000069 two38423 2023-07-10 13:21:23.242684-07 1 1 00065652 geneprod ATP:0000069 two38423 2024-02-16 16:39:43.445707-08 1 1 00065675 geneprod ATP:0000069 two38423 2023-07-10 13:21:23.265445-07 1 1 00065721 catalyticact ATP:0000061 two1843 Curated for GO (by WB) methanethiol oxidase activity 2023-11-02 11:59:46.312991-07 0 1 00065800 geneprod ATP:0000069 two38423 2023-07-27 12:25:57.768105-07 1 1 00065825 geneprod ATP:0000069 two38423 2023-07-31 14:53:06.839743-07 1 1 00065876 geneprod ATP:0000069 two38423 colocalization 2023-08-09 13:59:45.699703-07 1 1 00065879 geneprod ATP:0000069 two38423 2023-08-10 14:45:46.024081-07 1 1 00065930 geneprod ATP:0000069 two38423 2023-09-12 18:42:39.594889-07 1 1 00065933 geneprod ATP:0000069 two38423 2023-08-31 22:39:19.715633-07 1 1 00065936 geneprod ATP:0000069 two38423 2023-09-12 18:42:39.607941-07 1 1 00065946 geneprod ATP:0000069 two38423 2023-09-12 18:42:39.610435-07 1 1 00065950 geneprod ATP:0000069 two38423 2023-09-12 18:42:39.615485-07 1 1 00066002 geneprod ATP:0000069 two38423 2023-09-26 10:37:45.768033-07 1 1 00066031 geneprod ATP:0000069 two38423 2023-09-26 10:05:39.176103-07 1 1 00066073 geneprod ATP:0000069 two38423 2023-11-03 16:43:41.510707-07 1 1 00066078 geneprod ATP:0000069 two38423 2023-11-03 16:43:41.51462-07 1 1 00066085 geneprod ATP:0000069 two38423 2023-11-03 16:43:41.521297-07 1 1 00066087 geneprod ATP:0000069 two38423 2023-11-03 16:43:41.524528-07 1 1 00066105 geneprod ATP:0000069 two38423 2023-11-03 16:43:41.528081-07 1 1 00066107 geneprod ATP:0000069 two38423 2023-11-03 16:43:41.529699-07 1 1 00066136 geneprod ATP:0000069 two38423 2023-11-03 16:43:41.542518-07 1 1 00066137 geneprod ATP:0000069 two38423 2023-11-03 16:43:41.544283-07 1 1 00066200 geneprod ATP:0000069 two38423 2023-12-08 14:00:27.372713-08 1 1 00066210 geneprod ATP:0000069 two38423 2023-12-08 14:39:08.981404-08 1 1 00066211 geneprod ATP:0000069 two38423 2024-02-14 14:19:30.993089-08 1 1 00066214 geneprod ATP:0000069 two38423 2023-12-08 10:46:28.046317-08 1 1 00066226 catalyticact ATP:0000061 two1843 Curated for GO (by WB) SAD-1 protein serine/threonine kinase activity 2024-06-04 07:41:12.287396-07 0 1 00066282 geneprod ATP:0000069 two38423 2024-02-13 16:07:56.514123-08 1 1 00066383 geneprod ATP:0000069 two38423 2024-01-23 15:24:54.565518-08 1 1 00066406 geneprod ATP:0000069 two38423 neurexin-urboID 2024-01-23 15:31:40.171776-08 1 1 00066419 geneprod ATP:0000069 two38423 2024-01-30 12:40:33.088712-08 1 1 00066420 geneprod ATP:0000069 two38423 2024-01-30 12:40:33.090528-08 1 1 00066428 geneprod ATP:0000069 two38423 2024-06-06 16:44:57.823667-07 1 1 00066440 geneprod ATP:0000069 two38423 2024-02-13 16:07:56.526531-08 1 1 00066448 geneprod ATP:0000069 two38423 2024-02-13 16:07:56.532935-08 1 1 00066457 geneprod ATP:0000069 two38423 2024-02-13 16:07:56.535089-08 1 1 00066482 geneprod ATP:0000069 two38423 2024-02-13 16:07:56.543439-08 1 1 00066507 geneprod ATP:0000069 two38423 ms, cryo-em 2024-02-16 11:40:52.9443-08 1 1 00066508 geneprod ATP:0000069 two38423 2024-02-16 16:39:43.485922-08 1 1 00066518 geneprod ATP:0000069 two38423 2024-02-20 16:33:15.673459-08 1 1 00066551 geneprod ATP:0000069 two38423 2024-03-06 11:41:21.003975-08 1 1 00066561 catalyticact ATP:0000061 two1843 Curated for GO (by WB) In vitro kinase assay was performed with C. elegans PLK-1 and the GST-LMN-1 head [H] or tail [T] fragments as substrates. 2024-06-03 08:18:35.370169-07 0 1 00066567 geneprod ATP:0000069 two38423 2024-03-14 16:01:38.476135-07 1 1 00066573 geneprod ATP:0000069 two38423 2024-03-14 15:45:34.081811-07 1 1 00066595 geneprod ATP:0000069 two38423 2024-03-22 16:31:58.160599-07 1 1 00066616 geneprod ATP:0000069 two38423 ip-ms 2024-03-22 16:31:58.171311-07 1 1 00066662 catalyticact ATP:0000061 two1843 Curated for GO (by WB) protein serine/threonine kinase activity (GO:0004674) 2024-05-14 06:46:22.851824-07 0 1 00066662 geneprod ATP:0000069 two38423 2024-04-18 23:42:52.61164-07 1 1 00066679 geneprod ATP:0000069 two38423 2024-04-23 16:54:13.73266-07 1 1 00066706 geneprod ATP:0000069 two38423 2024-04-19 20:11:40.470691-07 1 1 00066712 geneprod ATP:0000069 two38423 2024-04-19 20:11:40.474208-07 1 1 00066720 geneprod ATP:0000069 two38423 2024-04-23 13:51:44.38594-07 1 1 00066743 geneprod ATP:0000069 two38423 2024-05-16 14:31:37.845881-07 1 1 00066748 geneprod ATP:0000069 two38423 2024-05-16 14:31:37.859351-07 1 1 00066750 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PRMT-5 histone H4R3 methyltransferase activity (GO:0044020) 2024-08-27 07:11:37.428897-07 0 1 00066783 geneprod ATP:0000069 two38423 2024-05-13 17:47:17.907713-07 1 1 00066799 geneprod ATP:0000069 two38423 2024-06-06 16:56:44.536062-07 1 1 00066824 catalyticact ATP:0000061 two1843 Curated for GO (by WB) DYF-5 protein serine/threonine kinase activity on OSM-3 2025-06-10 11:17:23.468351-07 0 1 00066827 geneprod ATP:0000069 two38423 2024-06-10 12:00:01.007287-07 1 1 00066857 geneprod ATP:0000069 two38423 2024-06-10 12:00:01.016781-07 1 1 00066916 geneprod ATP:0000069 two38423 2024-06-25 15:26:42.914415-07 1 1 00066918 catalyticact ATP:0000061 two1843 Curated for GO (by WB) ZYG-1 protein serine/threonine kinase activity on SAS-5 2024-07-15 11:49:11.200781-07 0 1 00067044 geneprod ATP:0000069 two38423 IP-MS 2024-07-15 15:56:14.035656-07 1 1 00067142 geneprod ATP:0000069 two38423 turbo-ID 2024-08-28 15:25:07.798117-07 1 1 00067175 geneprod ATP:0000069 two38423 turbo-ID 2024-08-28 13:02:42.159981-07 1 1 00067208 geneprod ATP:0000069 two38423 2024-11-07 16:42:35.297773-08 1 1 00067211 geneprod ATP:0000069 two38423 2024-09-10 17:44:31.042542-07 1 1 00067291 geneprod ATP:0000069 two38423 2024-10-10 17:15:22.372324-07 1 1 00067308 geneprod ATP:0000069 two38423 2024-09-30 17:37:33.222305-07 1 1 00067364 geneprod ATP:0000069 two38423 2024-10-18 20:22:01.736953-07 1 1 00067365 geneprod ATP:0000069 two38423 turbo-ID 2024-10-18 14:49:42.280021-07 1 1 00067367 geneprod ATP:0000069 two38423 2024-10-18 14:49:42.285481-07 1 1 00067368 geneprod ATP:0000069 two38423 2024-10-18 14:49:42.289355-07 1 1 00067387 geneprod ATP:0000069 two38423 2024-10-28 20:30:06.634064-07 1 1 00067579 geneprod ATP:0000069 two38423 2025-03-07 14:17:39.939359-08 1 1 00067588 geneprod ATP:0000069 two38423 ms-spec 2024-12-23 17:55:31.283926-08 1 1 00067593 catalyticact ATP:0000061 two1843 Curated for GO (by WB) PLK-2 phosphorylates SYP-5 2025-04-21 06:44:17.487986-07 0 1 00067593 geneprod ATP:0000069 two38423 2025-01-13 16:40:37.244865-08 1 1 00067618 geneprod ATP:0000069 two38423 2025-01-13 16:40:37.269011-08 1 1 00067619 geneprod ATP:0000069 two38423 2025-01-13 16:40:37.271242-08 1 1 00067649 geneprod ATP:0000069 two38423 2025-01-23 16:34:44.332354-08 1 1 00067660 geneprod ATP:0000069 two38423 2025-01-07 15:17:59.667757-08 1 1 00067667 geneprod ATP:0000069 two38423 2025-01-07 15:17:59.684954-08 1 1 00067673 geneprod ATP:0000069 two38423 2025-01-07 15:17:59.690125-08 1 1 00067685 geneprod ATP:0000069 two38423 2025-01-07 13:08:40.198532-08 1 1 00067812 geneprod ATP:0000069 two38423 2025-02-13 11:32:18.2924-08 1 1 00067824 geneprod ATP:0000069 two38423 2025-03-25 16:06:50.319642-07 1 1 00067826 geneprod ATP:0000069 two38423 2025-03-25 16:06:50.331453-07 1 1 00067838 geneprod ATP:0000069 two38423 2025-03-07 14:17:39.945321-08 1 1 00067855 geneprod ATP:0000069 two38423 2025-03-07 14:17:39.949464-08 1 1 00067861 geneprod ATP:0000069 two38423 2025-03-25 16:10:36.145414-07 1 1 00067865 geneprod ATP:0000069 two38423 2025-03-07 14:17:39.955732-08 1 1 00067872 geneprod ATP:0000069 two38423 turboID 2025-03-17 13:47:45.983018-07 1 1 00067890 geneprod ATP:0000069 two38423 2025-03-28 17:30:32.168819-07 1 1 00067896 geneprod ATP:0000069 two38423 IP-ms 2025-03-28 17:30:32.179101-07 1 1 00068076 geneprod ATP:0000069 two38423 2025-04-28 13:39:32.109022-07 1 1 00068079 catalyticact ATP:0000061 two1843 Curated for GO (by WB) NEKL-3 protein serine/threonine kinase activity on OSM-3 2025-05-16 10:13:49.60895-07 0 1 00068080 geneprod ATP:0000069 two38423 2025-04-28 13:34:29.065678-07 1 1 00068108 catalyticact ATP:0000061 two1843 Curated for GO (by WB) Note that there are multiple potential CMK-1 substrates but TAX-6 is the primary substrate studied in the paper and I'm not sure that we'll want all the substrates in as GO MF inputs. 2025-06-10 10:52:14.919806-07 0 1 00068108 geneprod ATP:0000069 two38423 in vitro kinase assay 2025-05-19 17:43:24.733462-07 1 1 00068122 geneprod ATP:0000069 two38423 2025-05-19 17:43:24.744563-07 1 1 00068141 geneprod ATP:0000069 two38423 turbo-ID 2025-05-19 15:10:59.443689-07 1 1 00068151 geneprod ATP:0000069 two38423 2025-05-19 14:51:09.486006-07 1 1 00068182 geneprod ATP:0000069 two38423 2025-05-30 16:02:10.142449-07 1 1 00068194 catalyticact ATP:0000061 two1843 Curated for GO (by WB) cdk-1 protein serine/threonine kinase activity on sas-6 2025-05-27 08:35:22.977591-07 0 1 00068194 geneprod ATP:0000069 two38423 2025-05-30 15:24:48.036934-07 1 1 00068228 transporter ATP:0000062 two1843 Curated for GO (by WB) IMP evidence for purine nucleoside transmembrane transporter activity 2025-09-05 08:11:36.618879-07 0 1 00068274 geneprod ATP:0000069 two38423 2025-06-23 23:18:48.385031-07 1 1 00068277 geneprod ATP:0000069 two38423 2025-09-09 16:44:40.644189-07 1 1 00068291 geneprod ATP:0000069 two38423 2025-09-09 16:44:40.64717-07 1 1 00068326 geneprod ATP:0000069 two38423 2025-11-25 12:48:12.189706-08 1 1 00068379 geneprod ATP:0000069 two38423 2025-08-04 16:48:10.059896-07 1 1 00068382 geneprod ATP:0000069 two38423 KNL-2 IP-MS 2025-08-04 16:58:43.120926-07 1 1 00068391 geneprod ATP:0000069 two38423 2025-08-04 16:48:10.070645-07 1 1 00068415 geneprod ATP:0000069 two38423 2025-08-04 12:51:23.568939-07 1 1 00068416 geneprod ATP:0000069 two38423 2025-08-04 12:31:20.397654-07 1 1 00068447 geneprod ATP:0000069 two38423 2026-04-02 15:47:35.585014-07 1 1 00068465 geneprod ATP:0000069 two38423 2025-08-18 15:31:02.585575-07 1 1 00068491 geneprod ATP:0000069 two38423 2025-08-18 15:27:44.249976-07 1 1 00068525 geneprod ATP:0000069 two38423 2025-09-09 15:32:56.272975-07 1 1 00068598 geneprod ATP:0000069 two38423 2026-03-24 18:16:33.930228-07 1 1 00068601 geneprod ATP:0000069 two38423 2026-03-24 18:16:33.932492-07 1 1 00068723 geneprod ATP:0000069 two38423 2025-11-25 13:25:12.998289-08 1 1 00068743 catalyticact ATP:0000061 two1843 Curated for GO (by WB) fmo-1, fmo-2, and fmo-4 monooxygenase activity 2026-04-07 14:09:02.748098-07 0 1 00068749 geneprod ATP:0000069 two38423 2025-11-25 13:25:13.000298-08 1 1 00068820 catalyticact ATP:0000061 two1843 Curated for GO (by WB) fat-1 omega-3 fatty acid desaturase activity 2026-04-07 12:45:39.789396-07 0 1 00068835 catalyticact ATP:0000061 two1843 Curated for GO (by WB) dpf-3 and human DPP4 tripeptidyl peptidase activity 2026-01-30 07:04:32.421472-08 0 1 00068838 geneprod ATP:0000069 two38423 2025-11-25 13:25:13.00436-08 1 1 00068844 catalyticact ATP:0000061 two1843 Curated for GO (by WB) mei-1 and mei-2 - microtubule-severing ATPase activity and ATPase activator activity 2026-04-06 14:46:10.864252-07 0 1 00068844 geneprod ATP:0000069 two38423 2025-11-25 13:25:13.008319-08 1 1 00069040 catalyticact ATP:0000061 two1843 Curated for GO (by WB) dpf-3 dipeptidyl peptidase activity 2026-01-30 08:18:46.994368-08 0 1 00069101 catalyticact ATP:0000061 two1843 Curated for GO (by WB) zk1098.3 endo and exonuclease activities 2026-04-28 12:35:42.672987-07 0 1 00069288 geneprod ATP:0000069 two38423 turbo-ID 2026-03-24 17:07:42.7271-07 1 1 00069613 geneprod ATP:0000069 two38423 2026-05-05 17:36:43.966782-07 1 1 00069614 geneprod ATP:0000069 two38423 2026-05-05 17:36:43.971934-07 1 1 00069617 geneprod ATP:0000069 two38423 IP-MS 2026-05-05 17:36:43.9762-07 1 1 00069637 geneprod ATP:0000069 two38423 2026-05-11 17:46:36.880379-07 1 1 00069638 geneprod ATP:0000069 two38423 2026-05-11 17:46:36.883561-07 1 1